LOCUS       DAPBBV010000001       137823 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.001, whole genome shotgun sequence.
ACCESSION   DAPBBV010000001 DAPBBV010000000
VERSION     DAPBBV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 137823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 137823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..137823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.001"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            212..604
                     /locus_tag="RD486_000001"
     CDS             212..604
                     /locus_tag="RD486_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7661774.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="RD486_000002"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="RD486_000002"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HDT7661775.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="RD486_000003"
     CDS             3165..4775
                     /locus_tag="RD486_000003"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HDT7661776.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="RD486_000004"
     CDS             5067..5936
                     /locus_tag="RD486_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HDT7661777.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="RD486_000005"
     CDS             6101..7372
                     /locus_tag="RD486_000005"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDT7661778.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="RD486_000006"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="RD486_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDT7661779.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="RD486_000007"
     CDS             8763..9026
                     /locus_tag="RD486_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDT7661780.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="RD486_000008"
     CDS             9471..9920
                     /locus_tag="RD486_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7661781.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="RD486_000009"
     CDS             9977..11395
                     /locus_tag="RD486_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7661782.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="RD486_000010"
     CDS             11395..12255
                     /locus_tag="RD486_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDT7661783.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="RD486_000011"
     CDS             12429..13202
                     /locus_tag="RD486_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7661784.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="RD486_000012"
     CDS             13349..13714
                     /locus_tag="RD486_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HDT7661785.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="RD486_000013"
     CDS             complement(13862..15070)
                     /locus_tag="RD486_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7661786.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="RD486_000014"
     CDS             complement(15089..15367)
                     /locus_tag="RD486_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661787.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="RD486_000015"
     CDS             15521..16216
                     /locus_tag="RD486_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7661788.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="RD486_000016"
     CDS             complement(16658..17455)
                     /locus_tag="RD486_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HDT7661789.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="RD486_000017"
     CDS             complement(17452..18636)
                     /locus_tag="RD486_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDT7661790.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="RD486_000018"
     CDS             complement(18661..19908)
                     /locus_tag="RD486_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDT7661791.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="RD486_000019"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="RD486_000019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDT7661792.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="RD486_000020"
     CDS             21888..22202
                     /locus_tag="RD486_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDT7661793.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="RD486_000021"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="RD486_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDT7661794.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="RD486_000022"
     CDS             22887..23531
                     /locus_tag="RD486_000022"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDT7661795.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="RD486_000023"
     CDS             23546..23875
                     /locus_tag="RD486_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HDT7661796.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="RD486_000024"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="RD486_000024"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDT7661797.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="RD486_000025"
     CDS             24863..25687
                     /locus_tag="RD486_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDT7661798.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="RD486_000026"
     CDS             25680..26027
                     /locus_tag="RD486_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HDT7661799.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="RD486_000027"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="RD486_000027"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDT7661800.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="RD486_000028"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="RD486_000028"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDT7661801.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="RD486_000029"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="RD486_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDT7661802.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="RD486_000030"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="RD486_000030"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDT7661803.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="RD486_000031"
     CDS             31657..32451
                     /locus_tag="RD486_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7661804.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="RD486_000032"
     CDS             32441..34483
                     /locus_tag="RD486_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7661805.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="RD486_000033"
     CDS             34764..34913
                     /locus_tag="RD486_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HDT7661806.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="RD486_000034"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="RD486_000034"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HDT7661807.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="RD486_000035"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="RD486_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDT7661808.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="RD486_000036"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="RD486_000036"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDT7661809.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="RD486_000037"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="RD486_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDT7661810.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="RD486_000038"
     CDS             39330..40412
                     /locus_tag="RD486_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDT7661811.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="RD486_000039"
     CDS             40412..41215
                     /locus_tag="RD486_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDT7661812.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="RD486_000040"
     CDS             41285..42025
                     /locus_tag="RD486_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7661813.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="RD486_000041"
     CDS             42036..43040
                     /locus_tag="RD486_000041"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDT7661814.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="RD486_000042"
     CDS             complement(43085..44929)
                     /locus_tag="RD486_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661815.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45141..45659
                     /locus_tag="RD486_000043"
     CDS             45141..45659
                     /locus_tag="RD486_000043"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7661816.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45787..46470
                     /locus_tag="RD486_000044"
     CDS             45787..46470
                     /locus_tag="RD486_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDT7661817.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46779..46852
                     /locus_tag="RD486_000045"
     tRNA            46779..46852
                     /locus_tag="RD486_000045"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46813..46815,aa:Arg,seq:tct)
     gene            47011..47370
                     /locus_tag="RD486_000046"
     CDS             47011..47370
                     /locus_tag="RD486_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HDT7661818.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47493..49124
                     /locus_tag="RD486_000047"
     CDS             47493..49124
                     /locus_tag="RD486_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HDT7661819.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49186..49827)
                     /locus_tag="RD486_000048"
     CDS             complement(49186..49827)
                     /locus_tag="RD486_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDT7661820.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50013..50089
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50109..50417
                     /gene="rplU"
                     /locus_tag="RD486_000049"
     CDS             50109..50417
                     /gene="rplU"
                     /locus_tag="RD486_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDT7661821.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50444..50788
                     /locus_tag="RD486_000050"
     CDS             50444..50788
                     /locus_tag="RD486_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDT7661822.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50801..51094
                     /gene="rpmA"
                     /locus_tag="RD486_000051"
     CDS             50801..51094
                     /gene="rpmA"
                     /locus_tag="RD486_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDT7661823.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51528..54335
                     /locus_tag="RD486_000052"
     CDS             51528..54335
                     /locus_tag="RD486_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7661824.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            54526..55017
                     /locus_tag="RD486_000053"
     CDS             54526..55017
                     /locus_tag="RD486_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7661825.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55120..56109
                     /gene="manX"
                     /locus_tag="RD486_000054"
     CDS             55120..56109
                     /gene="manX"
                     /locus_tag="RD486_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HDT7661826.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56142..56945
                     /locus_tag="RD486_000055"
     CDS             56142..56945
                     /locus_tag="RD486_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HDT7661827.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56966..57880
                     /locus_tag="RD486_000056"
     CDS             56966..57880
                     /locus_tag="RD486_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HDT7661828.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVERWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            57963..58337
                     /locus_tag="RD486_000057"
     CDS             57963..58337
                     /locus_tag="RD486_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HDT7661829.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58476..58721
                     /locus_tag="RD486_000058"
     CDS             58476..58721
                     /locus_tag="RD486_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7661830.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            58893..59957
                     /locus_tag="RD486_000059"
     CDS             58893..59957
                     /locus_tag="RD486_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDT7661831.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60203..60628
                     /locus_tag="RD486_000060"
     CDS             60203..60628
                     /locus_tag="RD486_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7661832.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60621..61070
                     /gene="nusB"
                     /locus_tag="RD486_000061"
     CDS             60621..61070
                     /gene="nusB"
                     /locus_tag="RD486_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDT7661833.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61167..62021
                     /locus_tag="RD486_000062"
     CDS             61167..62021
                     /locus_tag="RD486_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HDT7661834.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62022..63359
                     /locus_tag="RD486_000063"
     CDS             62022..63359
                     /locus_tag="RD486_000063"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDT7661835.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63364..63588
                     /locus_tag="RD486_000064"
     CDS             63364..63588
                     /locus_tag="RD486_000064"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDT7661836.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63590..64480
                     /locus_tag="RD486_000065"
     CDS             63590..64480
                     /locus_tag="RD486_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDT7661837.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64489..65307
                     /locus_tag="RD486_000066"
     CDS             64489..65307
                     /locus_tag="RD486_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HDT7661838.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65414..65863
                     /locus_tag="RD486_000067"
     CDS             65414..65863
                     /locus_tag="RD486_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDT7661839.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            65881..67563
                     /gene="recN"
                     /locus_tag="RD486_000068"
     CDS             65881..67563
                     /gene="recN"
                     /locus_tag="RD486_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDT7661840.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67618..67734)
                     /locus_tag="RD486_000069"
     CDS             complement(67618..67734)
                     /locus_tag="RD486_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HDT7661841.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67807..68763)
                     /locus_tag="RD486_000070"
     CDS             complement(67807..68763)
                     /locus_tag="RD486_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7661842.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            68934..69302
                     /locus_tag="RD486_000071"
     CDS             68934..69302
                     /locus_tag="RD486_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HDT7661843.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            69471..69902
                     /gene="mraZ"
                     /locus_tag="RD486_000072"
     CDS             69471..69902
                     /gene="mraZ"
                     /locus_tag="RD486_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDT7661844.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            69923..70882
                     /gene="rsmH"
                     /locus_tag="RD486_000073"
     CDS             69923..70882
                     /gene="rsmH"
                     /locus_tag="RD486_000073"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDT7661845.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            70887..71288
                     /gene="ftsL"
                     /locus_tag="RD486_000074"
     CDS             70887..71288
                     /gene="ftsL"
                     /locus_tag="RD486_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDT7661846.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            71289..73481
                     /locus_tag="RD486_000075"
     CDS             71289..73481
                     /locus_tag="RD486_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDT7661847.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGMFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            73507..74469
                     /locus_tag="RD486_000076"
     CDS             73507..74469
                     /locus_tag="RD486_000076"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDT7661848.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            74483..75844
                     /locus_tag="RD486_000077"
     CDS             74483..75844
                     /locus_tag="RD486_000077"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDT7661849.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYRHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            75870..76958
                     /gene="murG"
                     /locus_tag="RD486_000078"
     CDS             75870..76958
                     /gene="murG"
                     /locus_tag="RD486_000078"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDT7661850.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            76973..78193
                     /locus_tag="RD486_000079"
     CDS             76973..78193
                     /locus_tag="RD486_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HDT7661851.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            78349..79674
                     /gene="ftsA"
                     /locus_tag="RD486_000080"
     CDS             78349..79674
                     /gene="ftsA"
                     /locus_tag="RD486_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDT7661852.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            79697..80938
                     /gene="ftsZ"
                     /locus_tag="RD486_000081"
     CDS             79697..80938
                     /gene="ftsZ"
                     /locus_tag="RD486_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDT7661853.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            80955..81632
                     /locus_tag="RD486_000082"
     CDS             80955..81632
                     /locus_tag="RD486_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDT7661854.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            81646..82245
                     /locus_tag="RD486_000083"
     CDS             81646..82245
                     /locus_tag="RD486_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDT7661855.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            82260..82547
                     /locus_tag="RD486_000084"
     CDS             82260..82547
                     /locus_tag="RD486_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDT7661856.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            82596..83378
                     /locus_tag="RD486_000085"
     CDS             82596..83378
                     /locus_tag="RD486_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDT7661857.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            83399..84106
                     /locus_tag="RD486_000086"
     CDS             83399..84106
                     /locus_tag="RD486_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDT7661858.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            84368..87166
                     /gene="ileS"
                     /locus_tag="RD486_000087"
     CDS             84368..87166
                     /gene="ileS"
                     /locus_tag="RD486_000087"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDT7661859.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVAWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(87215..88741)
                     /locus_tag="RD486_000088"
     CDS             complement(87215..88741)
                     /locus_tag="RD486_000088"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDT7661860.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(88756..89403)
                     /locus_tag="RD486_000089"
     CDS             complement(88756..89403)
                     /locus_tag="RD486_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HDT7661861.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(89587..89916)
                     /locus_tag="RD486_000090"
     CDS             complement(89587..89916)
                     /locus_tag="RD486_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HDT7661862.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            90093..90821
                     /gene="sfsA"
                     /locus_tag="RD486_000091"
     CDS             90093..90821
                     /gene="sfsA"
                     /locus_tag="RD486_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HDT7661863.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            90837..91850
                     /locus_tag="RD486_000092"
     CDS             90837..91850
                     /locus_tag="RD486_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7661864.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            91850..93127
                     /locus_tag="RD486_000093"
     CDS             91850..93127
                     /locus_tag="RD486_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7661865.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            93190..95892
                     /locus_tag="RD486_000094"
     CDS             93190..95892
                     /locus_tag="RD486_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7661866.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            96044..96361
                     /locus_tag="RD486_000095"
     CDS             96044..96361
                     /locus_tag="RD486_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7661867.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            96391..96711
                     /locus_tag="RD486_000096"
     CDS             96391..96711
                     /locus_tag="RD486_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7661868.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            96819..98279
                     /locus_tag="RD486_000097"
     CDS             96819..98279
                     /locus_tag="RD486_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7661869.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            98347..98568
                     /locus_tag="RD486_000098"
     CDS             98347..98568
                     /locus_tag="RD486_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661870.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            98599..98781
                     /locus_tag="RD486_000099"
     CDS             98599..98781
                     /locus_tag="RD486_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HDT7661871.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            98781..99194
                     /locus_tag="RD486_000100"
     CDS             98781..99194
                     /locus_tag="RD486_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDT7661872.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            99317..100498
                     /locus_tag="RD486_000101"
     CDS             99317..100498
                     /locus_tag="RD486_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7661873.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(100569..100733)
                     /locus_tag="RD486_000102"
     CDS             complement(100569..100733)
                     /locus_tag="RD486_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661874.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            100887..100960
                     /locus_tag="RD486_000103"
     tRNA            100887..100960
                     /locus_tag="RD486_000103"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100921..100923,aa:Arg,seq:cct)
     gene            complement(101029..102168)
                     /locus_tag="RD486_000104"
     CDS             complement(101029..102168)
                     /locus_tag="RD486_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7661875.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(102467..103102)
                     /locus_tag="RD486_000105"
     CDS             complement(102467..103102)
                     /locus_tag="RD486_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661876.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(103215..103850)
                     /locus_tag="RD486_000106"
     CDS             complement(103215..103850)
                     /locus_tag="RD486_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HDT7661877.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(103884..104345)
                     /locus_tag="RD486_000107"
     CDS             complement(103884..104345)
                     /locus_tag="RD486_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDT7661878.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(104475..104906)
                     /locus_tag="RD486_000108"
     CDS             complement(104475..104906)
                     /locus_tag="RD486_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDT7661879.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(104924..105244)
                     /locus_tag="RD486_000109"
     CDS             complement(104924..105244)
                     /locus_tag="RD486_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7661880.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            105543..106319
                     /locus_tag="RD486_000110"
     CDS             105543..106319
                     /locus_tag="RD486_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HDT7661881.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            106334..106537
                     /locus_tag="RD486_000111"
     CDS             106334..106537
                     /locus_tag="RD486_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7661882.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            106553..106891
                     /locus_tag="RD486_000112"
     CDS             106553..106891
                     /locus_tag="RD486_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HDT7661883.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            106878..107057
                     /locus_tag="RD486_000113"
     CDS             106878..107057
                     /locus_tag="RD486_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661884.1"
                     /translation="MGKFNRALVFSAPLIIYALELWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(107100..107570)
                     /locus_tag="RD486_000114"
     CDS             complement(107100..107570)
                     /locus_tag="RD486_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661885.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            107657..108355
                     /locus_tag="RD486_000115"
     CDS             107657..108355
                     /locus_tag="RD486_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HDT7661886.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            108533..108874
                     /locus_tag="RD486_000116"
     CDS             108533..108874
                     /locus_tag="RD486_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661887.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            108867..109538
                     /locus_tag="RD486_000117"
     CDS             108867..109538
                     /locus_tag="RD486_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HDT7661888.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            109544..110230
                     /locus_tag="RD486_000118"
     CDS             109544..110230
                     /locus_tag="RD486_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661889.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            110233..110982
                     /locus_tag="RD486_000119"
     CDS             110233..110982
                     /locus_tag="RD486_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7661890.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            110994..111263
                     /locus_tag="RD486_000120"
     CDS             110994..111263
                     /locus_tag="RD486_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661891.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            111268..111432
                     /locus_tag="RD486_000121"
     CDS             111268..111432
                     /locus_tag="RD486_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661892.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            111425..111727
                     /locus_tag="RD486_000122"
     CDS             111425..111727
                     /locus_tag="RD486_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661893.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            111724..111885
                     /locus_tag="RD486_000123"
     CDS             111724..111885
                     /locus_tag="RD486_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HDT7661894.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            111882..112187
                     /locus_tag="RD486_000124"
     CDS             111882..112187
                     /locus_tag="RD486_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661895.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            112187..112543
                     /locus_tag="RD486_000125"
     CDS             112187..112543
                     /locus_tag="RD486_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HDT7661896.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            112530..112748
                     /locus_tag="RD486_000126"
     CDS             112530..112748
                     /locus_tag="RD486_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661897.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            112745..113164
                     /locus_tag="RD486_000127"
     CDS             112745..113164
                     /locus_tag="RD486_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HDT7661898.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            113161..113718
                     /locus_tag="RD486_000128"
     CDS             113161..113718
                     /locus_tag="RD486_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HDT7661899.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            113715..114011
                     /locus_tag="RD486_000129"
     CDS             113715..114011
                     /locus_tag="RD486_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661900.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            114088..114501
                     /locus_tag="RD486_000130"
     CDS             114088..114501
                     /locus_tag="RD486_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HDT7661901.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            114810..114962
                     /locus_tag="RD486_000131"
     CDS             114810..114962
                     /locus_tag="RD486_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661902.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(114959..115234)
                     /locus_tag="RD486_000132"
     CDS             complement(114959..115234)
                     /locus_tag="RD486_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661903.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            115688..115894
                     /locus_tag="RD486_000133"
     CDS             115688..115894
                     /locus_tag="RD486_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661904.1"
                     /translation="MLGQCFGNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
     gene            116090..116257
                     /locus_tag="RD486_000134"
     CDS             116090..116257
                     /locus_tag="RD486_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDT7661905.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            116283..116627
                     /locus_tag="RD486_000135"
     CDS             116283..116627
                     /locus_tag="RD486_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDT7661906.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            116632..116913
                     /locus_tag="RD486_000136"
     CDS             116632..116913
                     /locus_tag="RD486_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661907.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            117016..117330
                     /locus_tag="RD486_000137"
     CDS             117016..117330
                     /locus_tag="RD486_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDT7661908.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            117308..119002
                     /locus_tag="RD486_000138"
     CDS             117308..119002
                     /locus_tag="RD486_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDT7661909.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            119022..120200
                     /locus_tag="RD486_000139"
     CDS             119022..120200
                     /locus_tag="RD486_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDT7661910.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            120163..120849
                     /locus_tag="RD486_000140"
     CDS             120163..120849
                     /locus_tag="RD486_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDT7661911.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            120849..122009
                     /locus_tag="RD486_000141"
     CDS             120849..122009
                     /locus_tag="RD486_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDT7661912.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            122019..122894
                     /locus_tag="RD486_000142"
     CDS             122019..122894
                     /locus_tag="RD486_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661913.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            122891..123202
                     /locus_tag="RD486_000143"
     CDS             122891..123202
                     /locus_tag="RD486_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661914.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            123192..123545
                     /locus_tag="RD486_000144"
     CDS             123192..123545
                     /locus_tag="RD486_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDT7661915.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            123535..123936
                     /locus_tag="RD486_000145"
     CDS             123535..123936
                     /locus_tag="RD486_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661916.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            123929..124333
                     /locus_tag="RD486_000146"
     CDS             123929..124333
                     /locus_tag="RD486_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661917.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            124345..124953
                     /locus_tag="RD486_000147"
     CDS             124345..124953
                     /locus_tag="RD486_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7661918.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            124973..125335
                     /locus_tag="RD486_000148"
     CDS             124973..125335
                     /locus_tag="RD486_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661919.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            125537..128968
                     /locus_tag="RD486_000149"
     CDS             125537..128968
                     /locus_tag="RD486_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDT7661920.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            129019..129756
                     /locus_tag="RD486_000150"
     CDS             129019..129756
                     /locus_tag="RD486_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7661921.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            129766..132057
                     /locus_tag="RD486_000151"
     CDS             129766..132057
                     /locus_tag="RD486_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7661922.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            132081..134207
                     /locus_tag="RD486_000152"
     CDS             132081..134207
                     /locus_tag="RD486_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661923.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            134224..134373
                     /locus_tag="RD486_000153"
     CDS             134224..134373
                     /locus_tag="RD486_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661924.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            134370..134816
                     /locus_tag="RD486_000154"
     CDS             134370..134816
                     /locus_tag="RD486_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661925.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            134818..134955
                     /locus_tag="RD486_000155"
     CDS             134818..134955
                     /locus_tag="RD486_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDT7661926.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            134993..135286
                     /locus_tag="RD486_000156"
     CDS             134993..135286
                     /locus_tag="RD486_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661927.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            135283..135507
                     /locus_tag="RD486_000157"
     CDS             135283..135507
                     /locus_tag="RD486_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDT7661928.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            135504..136529
                     /locus_tag="RD486_000158"
     CDS             135504..136529
                     /locus_tag="RD486_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7661929.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            136719..136792
                     /locus_tag="RD486_000159"
     tRNA            136719..136792
                     /locus_tag="RD486_000159"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:136753..136755,aa:Ile,seq:cat)
     gene            137469..137823
                     /locus_tag="RD486_000160"
                     /pseudo
     CDS             137469..137823
                     /locus_tag="RD486_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        45893 a        22982 c        28838 g        40110 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat
    45121 aaagaaagaa gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa
    45181 cgttgattat atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt
    45241 tgactcctta tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga
    45301 tatatgtacg accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg
    45361 aaaattcagg aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag
    45421 atttttatac aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa
    45481 atattatcgg tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg
    45541 catttgcatg gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag
    45601 catggaatac ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag
    45661 aatgttaaaa acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga
    45721 gaaaacactc atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg
    45781 agtagtatgc gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt
    45841 atgcgtaccc agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat
    45901 gtagcagaag taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga
    45961 cagcttcagc ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc
    46021 atggccacga caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg
    46081 atcgagaaag ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt
    46141 gaaggtcaag cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg
    46201 gatagtgcaa aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa
    46261 ggtggcgttt tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa
    46321 gagattcccc gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg
    46381 atggatcatc ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg
    46441 acaaaggaat cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg
    46501 attgaatcga gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta
    46561 aaggatacag gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc
    46621 aattgataac cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag
    46681 ttgggccaaa ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa
    46741 tttaattatc tataattatt gatgttccgc tgattcttgt catagtagct cagctggata
    46801 gagcatccgc cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa
    46861 ccgttagaaa ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt
    46921 ttcaaaggca aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa
    46981 ataaaactca tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact
    47041 ctagttgcaa ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac
    47101 acgacaagta gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca
    47161 ttgtttaaga accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct
    47221 tatctttctt ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt
    47281 gcattatatg gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct
    47341 ctgttggcat tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag
    47401 gaaactttgt gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt
    47461 ttagaaaatt tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa
    47521 aaaaagaatt ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca
    47581 cagtagctgc tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg
    47641 cggccgcagg tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg
    47701 gtttttatca aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg
    47761 caacaaaggg aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg
    47821 cagcaggact tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg
    47881 ggtttacttc aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg
    47941 ttcactcgga aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc
    48001 cgataaacac agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc
    48061 caaaaaaatg ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag
    48121 ttatgctatt gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca
    48181 gtagtaatcg tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc
    48241 cagctattag cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg
    48301 gccgaatggc aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa
    48361 atctgttgct tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg
    48421 tggccatcaa atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac
    48481 tgctctccat gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag
    48541 gtgttttgat tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta
    48601 ctaataaata ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct
    48661 ttgatttaag tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca
    48721 aaagcgctgc tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag
    48781 aaacggaaaa gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt
    48841 cttcagaaaa actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct
    48901 ccatgcgagg cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag
    48961 aaaaagcaga gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa
    49021 aacaactttc tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg
    49081 cgttgacagc tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac
    49141 agacaagact gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa
    49201 aagtgaagct agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa
    49261 aatagctgct ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc
    49321 atccttttgt tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt
    49381 aaccgtatat tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa
    49441 ttttggctgg accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga
    49501 acgagtaggt gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg
    49561 atgagtcacg cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt
    49621 taagccagtt gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac
    49681 atgcgtatca atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag
    49741 aggtccttgc ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc
    49801 ttgtatcagt tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat
    49861 aaaagaaaca caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt
    49921 attgcttgaa tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt
    49981 ctggtaagct agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta
    50041 ataagcacag catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc
    50101 tttatagcat gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac
    50161 aagcaatcta tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag
    50221 ttatcttagt aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg
    50281 ttgaaggtac tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac
    50341 ctaaaaaaca ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg
    50401 acgcgatcaa cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt
    50461 taagcgaaat gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg
    50521 tccttatgga agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa
    50581 cgggattgcc tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg
    50641 ttatctttat accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat
    50701 tctattagaa aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat
    50761 ccaaattaaa acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct
    50821 acaattattt gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc
    50881 aaaacgtcta ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta
    50941 ccgtcaacgc ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac
    51001 tttatttgca aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca
    51061 agtgtctgtt tatccagtag ctcaagaagc ttaattgaat cttatgatta aagaggttgt
    51121 gacaagactt ttgtcacagc cttttttgtt tataaaaata aaagttgtag tggaggctac
    51181 gaagtttact ttgtcttttt acacttaata tttttttgcc aatttggaat caggatgttt
    51241 tgataactat cgttttcaat tgatggaagc tatattgttt gctatcagtg aaataattat
    51301 atggtaaaca gtgttctttt tcttgtttcc attataaaaa tcgtatcggg atttttcgtt
    51361 cttttaaatt gaacatttct atctatccgc gtgttatcaa caaaacaaaa tcaggtaaat
    51421 agttgacgaa acagaaataa atacatagta ttatgttttg aagcctaagt acaatagtct
    51481 atagaaaagg agcgatacca ttggcaaaac gcattgaccg aatttatatg tatgtcaaag
    51541 aaaaaaccgc tcatttaaca aaggcagaat atgatcaagg agtaacaaca caggaaattg
    51601 ctgaagtgtt agggattcag cgaacaaata gcagtaaaga tctgaatcag ctagtgcgcg
    51661 aaggaaaact gataaagaca gacggacgac cagtacgtta catatatcaa acactcgtta
    51721 cgcacgtaaa gccagttaca aaacatgtag tcagttacaa agaaacgccg gtctctgaag
    51781 aaaaaaatac actccaaata gatactaagg atatctttgc aaaaatcatt ggagctaacg
    51841 gcagcatgaa aaattcagtg gaacaggcaa aagctgcgat tttgtatccg ccaagaggat
    51901 taaattgttt gattacagga cctaccggat caggaaagac ttattttgca cacgcgatgt
    51961 atcattttgc aaaagcgcat catgtaatag atgaggaaac ggaactgatt gttttcaatt
    52021 gtgctgatta tgccaataac cctgagcttt tgatgagtca tttatttggg tacgcaaaag
    52081 gtgcttttac aggcgcagat gaagaaaaaa tggggattat cgatcaagcg gatggcggta
    52141 tgctgttttt ggatgagatt caccggttgc cgcctgaagg tcaagaaatg atcttttact
    52201 ttatggatca tggaacttac agtcgtcttg gggaaacaac gaaatcccat gaagcaaatg
    52261 tacggatcgt aggtgcgacc acagaagacc caggttcttc tctattagaa acttttgttc
    52321 ggcgtatccc aatcaatatc aaacttccgg cttttgaaaa acgtcctgca aatgagaaag
    52381 tcgatttagt aaaaatcatg attgcccacg aagcaaaccg cacgcagcga aagatttctt
    52441 tgacagaaga tgtagcaaaa gcattgatcg gcagtgtgac ctatggaaat ataggacaat
    52501 tgaagtcaaa tatccagtta gtatgtgcac gaggatttct aaatcatatg caatcacccg
    52561 aaatctcgat cacaatcgat gatttgacag aagggattcg tagcggattg attcaattag
    52621 caagcaaccg cagtgcaatg gcagagcttt ctaaaatatt ggagccaaag ataactgtag
    52681 caccaaatga tacgatcatg aaaatccaat cggactccta tgagttacct tataatctat
    52741 atgatatcat cggagataaa gcagctttac tgaagtcgga tggtttggat caagaagcaa
    52801 tcaatcattt catttctaca gatatcaaca tccatctgaa gtctttctat aaagaccatg
    52861 gtttttcttt taatgcagac agcaaattag cagaatttgt agatccgaaa atcatagaag
    52921 tgaccaatca gatttatgta atggtcaaaa gatctttacc atatgagttt cagcaaaact
    52981 ttatttatgc tatgagcttg catatcagtt cttttttgaa aaaaatcaac ttaggagaag
    53041 aacggcatac gaatgataac atccgtgaga tggcttttga ttttccagat gaatatgctg
    53101 ttgcgaaaga agtgcgtagt tatatcgaaa cgtattttca agtggagatt ccagaaagtg
    53161 aagactatta cttgaccgtt ctactcgtct cgttacgggc aaatcaagca agcggcagaa
    53221 tcggtgtagt cgttgcagct cacggaaaca gcacagcaag cagtatggtc caagttgtcc
    53281 aacagttgtt agatgcagag aacgtacgag cagtagacat gcctttggat atggatccga
    53341 aaacagcatt ggaccgaatt gaacgcaatg tacaagaagt agatgaagga agcggggtca
    53401 tactcttagt agatatgggg tcccttgcgt cgtttaattc gcaaattcaa agagacactg
    53461 gaattccagt acgtactgtt gatatggtaa caacttctct agttttggaa actgtacgaa
    53521 aggtctcagt attagggaca gatctagata tgttgcatga atcattgaaa aattttcgag
    53581 gttacgcaga aatatcttct gtagaatctg ttcaggaagc aaaacctatt cataagaaaa
    53641 aagctgtttt ggctatctgc gcatctggcg aaggtacagc acaaagaatc aaagaattga
    53701 tcgaacgagc ggtaaacaag cgtcaagaaa cagaattaga agttctagct ttgtcgattg
    53761 tggaagtgaa agaagaactg ccagttatcc aaaaagaata tcagatcata gctactactg
    53821 ggattactga tttgaatatc caagccccat ttattccttt agaacgtttt attgatcaaa
    53881 atatcgaagt cattttggat cagttgctga tggaatcaga attggaggaa actgaattca
    53941 tctccctaga tgaagagtca gctaaaaata cgtgtgttga gtttatctct gataacttca
    54001 tctttattaa tggtagtaag ttaatcgatc caatgtggca attttctaca caaatctctc
    54061 agacgacggg aatcggcgat gaagaatatg gattcaaaat caacctagtg atgcacacag
    54121 caggaatgat cgaacgtatt attcggaatg aaccattgac tgtggaagaa aacgaattga
    54181 caaatacaac gaatgatcct ctttatagcc aattggcagc ctcagttgtt ctgttggaag
    54241 atcagataaa agtaaaagtg ccgatagaag aaatgtatta tctgctacgt ctagtccata
    54301 atcagttaga taaaaaagaa tacactgtgc catgaataca caaaaacgat acacttttat
    54361 agtgtatcgt ttttgtgtat tggttaagaa tcctttaaat tcaattagtg tatcgtaaaa
    54421 aagttggcac gctttttgct tatagtagtg tgtgctagga ggtggttgtt cacacagaaa
    54481 tgataggggt ttctgtgaag tagtgaggaa gaaggagttt tgcagatgga tattcgattg
    54541 gcacgtatag atgatcgttt aatccacggg caagtcgcaa cagtttggtc gaagcaaaca
    54601 ggtgttgaac gtatcattgt gatcagcgat gtagtcgctc aagataaatt gagaaagttt
    54661 ctactaaaag aagctgcacc gccggggatc acagcaaatg taataaccgt gcagaaaatg
    54721 attcaaatct atcatagtgg attattatca cgagcaaaag tgatgctttt attcaccaat
    54781 ccccaagatg ttgaagcggt tgtccgctgc ggtgtacagt tgaagtcgtt gaatatcggc
    54841 ggtatgagtt ttactgaagg caaatcaatg attaccaatt ttgtttcagt aaatcaacaa
    54901 gatattgatt cctttcgtta cttgaacagt caagaagtgg agttagagat tcgaaaagta
    54961 cctgctgaca ggaaaatcct tttgatggaa ctactagcga aaatcaaaaa ggtgtagcaa
    55021 gaatggttgt tggaaaaggt caaataattc tgttgtaatg gttagcaatt attaatattt
    55081 ttgaatttgt tacaacaaaa gtaaatagga ggtataaata tggtagggat tatcctagca
    55141 agtcatggac aatttgctga aggaatctta caatccggtt caatgatctt tggcgaacaa
    55201 gaaaacgtca aagccgtgat tttgaaacca agtgaaggtc cagatgactt gagagccaaa
    55261 ttggaagaag cggttgcttc ttttgataat caagacgaag tgttattctt agttgattta
    55321 tggggcggaa caccgttcaa tcaatcaaac acattattcg aagagcacaa agataaatgg
    55381 gcaatcgtca gcggtttgaa tttaccaatg ttgattgaag cctacgcatc acgcttttca
    55441 atggaatctg ctcatgaaat tgcagcacac atcattgaaa cagcaaaaga cggtgtaaaa
    55501 gtaaaaccgg aagaattaga accggcagaa gcaccgaaag cagcagttga agacgcacaa
    55561 cctaaaggag cacttccaga aggaactgtg gtcggagacg gaaaaatcaa atatgtatta
    55621 gcacgtgttg actcacgtct gttacatgga caagttgcga cagcttggac aaaagcagtg
    55681 caaccaaacc gtattatcgt tgtttcagat gcagtatcaa aggatgatct gcgtaagaga
    55741 ctaatcgaac aagctgctcc tccaggtgta aaagcaaatg ttattcctat tagcaaaatg
    55801 atcgaagtag caaaagaccc tcgttttgga aataccaaag cattgctttt atttgaaaat
    55861 cctgaagacg tattgacagc tgttgaaggt ggcgtagaca tcaaagaatt aaatgttggg
    55921 tcaatggcgc attcggtcgg taaagtcgtt gtaagtaaag tattgtctat gggacaagaa
    55981 gacgttgaag cgtttgagaa gcttgaacaa aaaggtgtga aattcgatgt acgtaaagta
    56041 cctaatgatt cacgcgataa catggatgat attttgaaaa aagcaaaagc tgaattagca
    56101 aaagcgtaat aaataatatt aaaatttata ggaggcttat catgtctatt atttcaataa
    56161 ttttagtcgt attagttgcc tttctagctg gtatggaagg tattcttgat gaatttcaat
    56221 ttcatcaacc actagtggca tgtacattga tcggtttagt taccggtaac ctcgaagctg
    56281 gtatcgtact tggcggtacg cttcagatga tcgctttagg ttgggcaaat atcggtgccg
    56341 ctgtagcacc agatgctgca ttagcatcag tagcatcagc aattatttta gttttaggtg
    56401 gacaaggtgt taaaggtgtt ccttctgcga tcgcgattgc cgttcctttg gctgttgcag
    56461 ggttgttctt aacaatgatc gtacgtacaa tcgctgttcc aatcgttcat ttgatggatg
    56521 cggctgctga agaaggaaac atccgtaagg ttgaaatgtg gcacatcatt gctgtatgtt
    56581 tacaaggggt tcgtatcgcg gtcccagcag cagcgttgct atttatccca gcacaaactg
    56641 tgcaatcatt ccttgaatca atgccagcat ggttaacaga tggtatggct atcggtgggg
    56701 gaatggtcgt agctgtaggt tacgctttgg taatcaacat gatggctaca aaagaagtat
    56761 ggccattctt cgttattggt ttcgttgtag ctgcaatttc tcaattaaca ttgattgctc
    56821 taggtgcttt aggtgttgca ttagctctta tttacttgaa cctttctaaa atgggtggtt
    56881 catcaaataa tggaggcgga agcaactctg gtgacccttt aggcgacatt ttgaatgact
    56941 attaatcttg aaggaggaaa ataaaatggc agaagaaaaa atcaaattat caaaaaaaga
    57001 tcgtttagct gttgcgtggc gctctacctt cattcaaggt tcatggaact acgaacgtat
    57061 gcaaaacggt ggctgggcat tttctatgat tccagcaatc aaaaaattat acaaaacaaa
    57121 agaagaacgt tctgcagcat taaaacgtca cttggaattc tttaatacac acccatacat
    57181 tgcttctcca attttagggg ttacattggc tctggaagaa gaacgtgcga atggcgcgcc
    57241 tgttgatgat gtagcgattc aaggggttaa agtaggtatg atgggtcctt tagctggtgt
    57301 tggtgaccca gtgttctggt ttacagtacg tccaatgcta ggtgcactag gtgcttcatt
    57361 agctatggga ggaaatatcc ttggaccaat catcttcttc ttaggttgga acattattcg
    57421 ttgggcattc atgtggtata cacaagaatt tggctacaaa gctggttcta aaattactga
    57481 tgacctttct ggcggattgt tacaagacgt aacaaaaggt gcttcaattt tagggatgtt
    57541 cgtattagct gcccttgtag aaagatgggt atcaatcaaa ttcttaccag ttgtatcaac
    57601 tgtaaaatta gataaaggtg cttacatcga atgggataaa ttgccttcag gtggtgaagg
    57661 aatcaagagt gcatttgaac aagttaataa tggcttagcc ctttctcctg aaaaggtaac
    57721 aacattacaa gacaacttag accaattgat tcctggttta gctgcattag gattaacatt
    57781 gttatgtatg tggttgctta agaaaaaggt ttctccaatc gttatcatcc ttggtttatt
    57841 cgtagtcggt gttgttggac acgtcatcgg acttttataa tccataaaaa tatagctcgg
    57901 gcgttgtccc gagctttttt tatatagtat actgttcata aacaaatatc tggagggaga
    57961 aaatggttca atcaatcaat acaaaagtag acttggtaat tgatgctact tcgtttacgg
    58021 gtctgacaga ttacgggcaa atcatgatag gtgataatgg ttttgagttt taccatgcgc
    58081 gagatagacg caaatatatc caaattccat gggaagaagt ggattatgta ctagcatcag
    58141 tcatgctaaa gggaaaatgg attcctcgat atgccattca aacgaaaaaa aatggtacat
    58201 acacattttc ttccaaagaa cctaaaaaag tgcttcgtgc gatcagagaa tatgtagatg
    58261 aagatagaat ggtacaatca ttgagtttct ttgatgtagt gaaacgtggt attcgtagta
    58321 tgtttaaacg caagtaaaaa ataaagaaaa cttctaagag gaggttttct ttattttttt
    58381 actttgcaga agaaaatatg aaatagcaaa accaattatt tgtccccttt aaatcccata
    58441 tgctaaaatt gattagcaaa gaaggaggtt atattatgag ttggttatgg acattgattg
    58501 ttggagccgt gatcggagca attgcaggtg cgatcaccag taaaggaaat tcgatgggct
    58561 gtgtaacgaa tatcattgct ggactagtcg gttcaagtat tggacaagcg attttcggcg
    58621 aatggggacc aaaagctgca ggtatggcac ttattccatc tattttaggc gcagtgattt
    58681 tggtagcagt tgtctcattt ttctttggaa aacgatcata agtttttaca aaatagtaaa
    58741 ctaaaaggag ttgcagcgag actgtgactc ctttttggct ttatttattt aaaataaaaa
    58801 gaagttttcc ggaaattttt atttaactgt cgtgtacgaa gaaaagtttg ctataatgga
    58861 aaaaagcgtg caaagaaaga gggagtttca ttatgatgct acgtgtagaa aaattgcgca
    58921 aaaaaatgca agaagaaaat ttggattcat ttttggttac cagtccgtac aatcttcgtt
    58981 acttaacgaa ctttacaggt acgacaggat tagctgttat tactttggaa aaagcatttt
    59041 ttattactga ttttcgttat accgagcagg cggcagcgca ggctcaaggg tttgaaatta
    59101 ttaaaaatgt cggacctatt tttgatgagg tagcaaactt agtacgcaaa gaagaactgc
    59161 actcattagc ttttgaggaa acaacagtct catttttaga atattcggtt ttagaagaaa
    59221 tcatcgatgc ggaattagta cctgtttcac agatgatcga agaactcaga gaagtgaaag
    59281 atgaagaaga aatcgctatt atcgaaaaag catgtcatat tgcggatatg gcatatgatc
    59341 acatcctgaa aatgatccaa ccgggcatga ctgagattga agtcgcaaat caactagact
    59401 tttatatgcg ttctcttggc gcttcaggtg tttcttttga tacgatcgtt gctagcggat
    59461 tgcgttcggc tatgccgcat ggtgtagcaa gcaaaaaaat catcgaacaa ggtgacttga
    59521 tcacattgga ctttggttgc tattacgaag ggtacgtttc cgatatgaca cgtacattcg
    59581 ctattggtga tcctggggaa aaattaaaag aaatttatca aatagtctta gatgctcaat
    59641 tagcagttat tgatgctgca aaaccaggaa tgactggtgt ccaattagat gcagttgcta
    59701 gagattatat ttcaaaacat ggttacgggg aagcatttgg acattctaca ggacatggga
    59761 tcggtttaga gatccacgaa ggaccaaacg tttcttctcg tgcagaaaag caatttgtac
    59821 caggaaatgt gatcactgat gaaccaggga tctacttacc aggaatcggt ggagtacgta
    59881 ttgaggatga cttgttgatc acagaagatg gaaatcgtgt gttgactcgt tcaccaaaag
    59941 aattgatcat cttatagttt catcaataga agaagtaagc gtaaaaatca gtgttcacag
    60001 actttgttat agaaaatcac tcgatttaat gatacactat agaagaactt ttaagctgta
    60061 agagataata aagttgggtg ttttctccaa ttcatagcag tttgcagctg atcggcggca
    60121 gttttcttac cacgtgatca ctatgccgca tcatagagaa ttcggatgta tctcgtgctt
    60181 aggcaaaggg aggaataaat aaatggcaga tgaaaaaaat ttgattttaa acgcaaacca
    60241 agatttagga gagatcgtga tcgctcctga agtcatcgaa gtaattatcg ggattgcagc
    60301 ttctaaagta gaaggcgtat acggaatgcg cggaactttt gccagcaatg tcactgaatt
    60361 attaggacgt gcagctcacg gaaaaggtgt ttacttagca aacgaggaag atggcttgaa
    60421 agtagatctt tactgttatc tagaatatgg tgtttcagtt cctaaagtag caatggaaat
    60481 gcaggaacgg gtcagccagc aagtcctttt catgacggat atcgatttat ctgaagtcaa
    60541 tatccatgta gtagctgttg ttcctgaaaa attagaacaa ccaacaatcg aagaactttt
    60601 tgaagacgaa gaggaagaga atgaataaag aattatcaag acacgagatt cgggaaatgg
    60661 cattgcaggc tttatttcca ttagacttca atgcagacct aacaaaagaa gatgcgattt
    60721 tcaacgcaat cgaattagac caccgcgaca tgatcaacga agatgaatca gagtttgttc
    60781 ctgtttatct tgatacgcta gttggcggtg tctgtgcaaa aaaagatgaa ttggataaag
    60841 tgattgaaaa acatttaaaa aacaattggc acatcaatcg gatctcaaaa atggatttgg
    60901 tgatcttgcg tatcgcgatt tttgaaatga cttatgtgac agatgtacca gcggctgttg
    60961 ctttaaatga agcaatcgag ttggcaaaaa catttagtga tgaccgttca cgtaaattcg
    61021 tcaacggtgt tttatccaat gtattgaaag aattagaagc tggggcgtaa gtcctagctt
    61081 ttttctatga atcatcataa acctgttata aatcgggaaa attctatggt agaatgaaaa
    61141 cacaaaaaat atctgggagt ggttagatgg cagaattgat taacggaaaa gaattagctg
    61201 aaaaaatgca ggcagagatt gctgaaaaaa tccaaaaatt gaaagataat ggtatccatc
    61261 ccggattagt cgttttattg gtaggggaaa atccagccag ccaaatctat gtaagaaata
    61321 aagaacgtgt agcaaaagaa atcggaatcc attcattggt agagcgttat cctgagacga
    61381 tttctgaaga cgaactactt gcagaaattg aaaaatacaa tcaagatcct agttttcatg
    61441 gtatattggt ccaattacca ttgccaaagc atatagatga agaaaagatc ctgttagcta
    61501 tccgccctga aaaagacgta gacggttttc atccgatgaa tttaggcaga ctccttgcgg
    61561 gtaaaccgga caagattcct tgtactccat acggcatcat gaaaatgttt gaagcttatt
    61621 ctatcgatcc ggcgggtaaa cgagcagtag ttatcggacg aagcaatatc gtcggtaaac
    61681 cgatggctca gctactcttg atggcagatg caactgttac tgttgctcat tctaaaaccg
    61741 aaaatctggc tgaactggca caagaagcag atattttagt cgtagcaata ggacgtggac
    61801 attttgtcac aaaagaattc gtaaaaccag gtgctgtagt gatagatgta gggatgaatc
    61861 gtgatgctaa cggtaagctg atcggtgatg tgaaatttga tgaagtggag cctattgcag
    61921 gctggatcac tcctgtgcca aagggtgtag ggccaatgac tatcacgatg ctgatgtatc
    61981 aaaccgtaaa atctgccgaa gcttttggag caggtgaata gatggcacaa gaatatttaa
    62041 ctgtcactac attaacgaag tatttgaaaa gaaaatttga tgccgatcct tatttagaac
    62101 gcgtatattt aacaggcgaa atatcgaatt tccgtttacg tgccaatgcc catcaatatt
    62161 tcagcttaaa agatgaccat gcaaaaatat ctgctattat gttcaaagga gcattccaaa
    62221 aattacgatt ccagccaaaa gaaggaatga aagtccttgt cgttgggcgt atttcattat
    62281 atgaagcggg aggttcttat caaatctatg tagagcacat ggagcctgat ggaataggtg
    62341 ctttatatca agaattggaa gaacgaaaag aaaagctgat gaaggaaggc ctttttcaag
    62401 ggcctaaaaa aatgctgcca cgtttcccaa agcgaatcgc ggtccttacc agtccaagcg
    62461 gagcggttat ccgcgatatc atcacgacgg tgaaaagaag atatccaatt gtccaattgg
    62521 ttttgttccc aacagttgta caaggaaacc aagcagcgga caatgttgtc aggaatatcc
    62581 agagagtaga agagatgggc aatttcgata caatgatcat cggtcgtggg ggtggttcga
    62641 ttgaggattt atggccgttt aatgaagagc gggttgctcg ggcgatttat caagctaata
    62701 cgccggtgat ttcatctgta ggacatgaaa cagataccac gatcgctgat ttagtagcag
    62761 atgttcgggc tgccactcca acagcagctg cagaattagc tgttcctgtt ttgtcagaag
    62821 agttgatgcg cattcaagaa cggcaagcta gattgcagca ggcgtttgta cgccagatcc
    62881 agcgcaaaca agaacggttc gagcgtgctc gacgttccta tgtatttcgg cagcctgaaa
    62941 gattgtatga aggtcagacc atcaaattag accagttgaa acagcgatta tatcaagcta
    63001 cacagcaaat ttatcatgcg aaagaaaaac aaacgatcgc attaagccac caattggaac
    63061 aagtggctcc gctttatcga gttaaagcag ctcgccaaga aactgcttat ctagaaaaac
    63121 gcttagaaga gaaaatccaa caatatatga aacaacagca gcagcgtttt gctcaagctg
    63181 ttcaatctct tgatttgttg agtccattga aaatcatggg aagaggctac agctatacga
    63241 cgttaaatga tcaagtagta aaaagtgtca ccgagattca tcaaggggat ttgctgacga
    63301 tccattatca agatggaatc gttaaaggac aagtacaaga gatagacaaa ggagaataaa
    63361 aatatggaaa atccaacttt tgaagagtca ctgcaagaat tagaaaaaat tgtcatgcag
    63421 ttagaacaag gagacgttcc attagaatca gctctagatt cgtttaaacg aggaatggaa
    63481 ttaagcaaac attgccaaga tacattagct aaagcagaag agaccttgac gaaaatgatg
    63541 acagaatcaa atgaagaagt tgattttgac ggaaacgagg aaagctgaga tgagattaac
    63601 tgacttttca gctattcatc tacctgctgt agaaaaagaa atcttgtctt ttttagatga
    63661 gcatacaacg gatagaggac tctatgatgc gatgagttat tcagtgaaag caggcgggaa
    63721 aagaatacgt cccttattac ttttaacggc cgttgcttcc tttgatgagc ctattgatgt
    63781 tcccgtctat caagtagcag ctgctttaga aatggtgcat acgtattcct tgatccacga
    63841 tgatttgcct gcgatggaca atgatgatct tcgtagagga aaacctacca atcataaagt
    63901 attcggcgaa gcattagcta tattggccgg agatggtttg cttacaggag cattccagct
    63961 aatcagtatg gcacacttag gtaattctcc taagcttctg ctgcttcagc aattagctgt
    64021 ttgtgcggga tcacaaggta tggttgctgg gcaagctgca gatatcgagg gcgaatcgaa
    64081 aaagctttct ttagaagaat tagcatttat tcatgaaaga aagacagggc atttgattcg
    64141 ttatgccttg ctggctggtg gcatattagc gaagcaacct gaagaaatct tattgctact
    64201 tcaacgatta gccgaacatt taggtttagc ttttcagata agagatgatc tactcgatgt
    64261 gattggtaca acgaaaacat tagggaaaac agctggtaaa gatgaacgta tggaaaaaaa
    64321 tacttacccg cgtttattag gcctagaaaa gacacgtgag gcgttggaga ttgagctgtt
    64381 atccgccaac aagatcatag acaaattaga agaggacgtt ttttcttttg atggcgggct
    64441 gatgcgccag atgatcaagc aatttgatgt ggagaaatga gggaaagaat ggaaaaagaa
    64501 cgcgtagatg tattagcggt caaacaagga ttatttgaaa caagagaaca agccaaacgt
    64561 tcagtgatgg ctggtttgat ttacaacgaa aaaaacgagc ggtttgataa accgggagaa
    64621 aaaattccag tgagtagtga attaagagtc aaaggtaaaa aacttcctta tgtttctcga
    64681 gggggattaa aattagaaaa agcactcaaa gcatttgatc tatctgttga aggaaaaaca
    64741 ttgttagata ttggtgcatc cactggcgga tttactgatg cagctttgca aaatggcgca
    64801 aaaatgagtt atgctttaga cgttggctac aatcagctag cttggaaaat aagacaagat
    64861 cctagagtcg tcgtaatgga aagagtgaat tttcgttatg caaaacccga agactttacc
    64921 ttaggaattc cagaagttgc tgttatcgat gtttctttta tttcactaaa actgatgctg
    64981 cctccattac atgctatttt aaaagaagag ggagaagtga ttgctttaat caaaccccaa
    65041 ttcgaagcag gcagagaagc tgtagggaaa aacggaattg ttcgtgaccc tcagacccat
    65101 caaaaagttt tagaagacat tttgtcattt gcggcacaag gtggatatga tgtgctggaa
    65161 ttaagttatt ctccgatcac ggggggagaa ggaaatatcg agttcttggc tcacttgagg
    65221 aaagtacccg aaagcggaac aatcaattca gctattaata tggcagaagt ggtttcaaat
    65281 gcacacgaac agtttgacca taaataaatt gtaactgtga aaatcaagtg agaagtatgc
    65341 ggattcttct ttattatacc aaggaaataa gctatcattg attaagaaga atatgctaag
    65401 gagcgaagac gtaatgagaa aaaaagatcg gcatcgtttg attactcgat tgttgagtga
    65461 gcaagatatc cgaaagcagg aagaatttgt tgaaatcctg aaaagcaaag gaatatctgt
    65521 tactcaagct acgatttcca gagatataaa ggaactgaaa ctgatcaagg taccggcttc
    65581 agatggcggc taccgttata gcataccagc tgaaacaaac gaagatgtaa atactaaatt
    65641 ggaaaaacta ttaaaagacg ctttcgtggc agttgaccaa atggaaaaat ttgttatttt
    65701 gaaaacattg ccgggaaatg cttcggcagc agcaaatttg attgataaac gttacaagaa
    65761 agaattattt tcgattatca atgatgacga taatgttttg atgattacac gaactgaaga
    65821 ccaggcagtt ttattgaaga aagacttcct gcattacctt taagttgagg agcgaatgtg
    65881 atgctacaag aaatcagtat tactaacttt gcgattattc cggaattgcg gctttctttt
    65941 cacgaaggaa tgaccgcgct gaccggagag actggtgcgg gtaaatccat tattatcgat
    66001 gctttaggtc tgttagcagg aggaagaggt tcaagcgatt atatacgtca aggagcagaa
    66061 aaatgtgtgc ttgaagggtt gtttgaacta ccaaaacaag aaggattctc tgaactgatg
    66121 gttgaattag ggatcgaaac agatgaggac aatctgattg ttcgacggga tatgtcctta
    66181 actggaaaaa atgtttgtcg agtgaatggt catattatca cattagctaa tctgagaaga
    66241 atcggcagtt atttagtaga tatccaagga caaaacgaac atcaggaact gctccagcct
    66301 gaatcacatc ttgctttatt ggatcgtttt ggagatgtag ctttccaaca gaagaaaaag
    66361 agttatcagc aagaatatat ctcttatcgt gagctggaaa aaagggtacg aaaagtgcag
    66421 caaaatgaaa aatcctatgt tcagagaata gatatgctcc atttccagca agaagaaata
    66481 gctgctgctg atttgcaagt cggagaagaa gagaaattaa aagaagaaag agaaaaactt
    66541 agcaattatc aaaaaattgc tgatggatta gctgcaggtt acggagcact gacgaataat
    66601 gaacaaaaca gtgtagatgg tgttggcttg gccgtttcag aactgcaagg gatcgcccat
    66661 ctagatgtgg agtatgaagc aatttatgaa aatatccaaa gtgcttacta tttgctgcaa
    66721 gatgcaatcg gcgatatgag tcgtcagatt gatttattgg agttagatga gagtcgttta
    66781 gaagaagtta cgcaacgttt agaattaatc cgacagttga aacgtaaata cggcgaatcc
    66841 attgagtcaa tattggctta ctatgacgaa atcaccgaag agctagcttc ttctgatttt
    66901 tcagaaggtc aattggacaa aatgaaagag gaactagagc aaaaagagct tctacttcag
    66961 caacaagccg cagatcttca tgaagcgcgt aaaaaaatcg caaaagaatt ggaaaaatcc
    67021 attctgcatg aattgaaaag tctgtatatg gaaaacactg agtttgaggt acgtttctta
    67081 aaagaagaaa atagacaatt gaatcatgat ggatttgacc aaatcgaatt ttacattacg
    67141 accaatccag gagagccact gaagcctttg gtgaaagtcg cttctggtgg cgaactgtct
    67201 cggatgttgc ttgctttgaa aactattttt tcttctgagc aaggtgtgac aagtattatt
    67261 tttgatgaag tggatacagg tgtgagcgga agagttgcac aggccatcgc agataaaatt
    67321 tctcaaatat cgaaatactc tcaagttttg tgcatcactc atctgcctca agttgctgca
    67381 gtcgccgact atcaatatta tattgtgaaa gcagtgattg atggacgtac gcaaacttct
    67441 gtttcagagt tgaaaacaaa agaaagagaa gaagaaattg cacgtatgct ggctggaagt
    67501 gagattacaa aactcacact cgaacatgca aaagaactat tgaaactcgc aaaaaggacc
    67561 tgagccacct cgcagtggtt caggtccttt tcagcagctg atagctatat tttattttta
    67621 catgacactc attacagcag tcaatacaac agatccaatc gttaaaatca gcattgtcca
    67681 aatgacaaat tttgttactt tagcaaaagt acttgtttgt tttttttcac gcattgtttt
    67741 caacctcgtc attaattagt tgattcaagt gtacaatctt ttttccattt ccacaagagg
    67801 gcttttttat aaaaacttcc ctttttttaa ataataggta gttacgatac aaataaataa
    67861 tgttaataga actagccata taaaggcatc atccctttca gcaataggta acttaatgtt
    67921 cattccatag atactgccga cgattgtcgg tatagttaaa ataatcgtta aagaagttaa
    67981 aattttcata atattattca gattattcga tacgattgct gaaaaagtct gattcatttg
    68041 ttctactagt tttaattgaa tgcgagaagt agtcattgcc tgctctgttt ccaccaatac
    68101 atcacgtaaa tgatttttca aagcatgatt ttcttggaaa agtttatttt gcgctagttc
    68161 tttcaatgca tctaaattag cagaagtcgc ttctctgaaa taaacgaggc ttttttggat
    68221 atccatgatt tgataaagtt gtttgttttc agtggatact tgaagtttgg cttccaaagt
    68281 atcgcattga gattgaagcg tagctaaata actgttgtaa gagagtgtga cctgccaaat
    68341 gaattgaaag aagatattga gattaggcga aatatcactt tttggaaagg tctggctaaa
    68401 gactttcttt aaaaacagtg gttcatgatt cgtaattgtg ataagcttct ttttgggcgt
    68461 caaaataata gagagcgggt atgtatccac ttgaaaataa ccgctaggac ttgttttagc
    68521 aaaaggatat tgtaacaata ataacgctgg ctttgtcaac tttgattgat tgaattcttc
    68581 tgtacgggaa ttttctgcat cgtccaatat ggaagtgatg taatctgacg gaatttcaaa
    68641 ttgatgtgtc agctgatgaa tctcttcttg attaggacgt tctacacaat accagatcgt
    68701 ttggtcagtt tcctttccgg tattacgcag tttctcatta tctaatgtaa aatatttgat
    68761 catgattttc ctcctgttgc ctgtttcttt tattataacg gatagggaat tggaatacat
    68821 ggaatgtgtt tgtaagatat agaatataac tgcataaatt taaataaaat gaaacagttg
    68881 tgtaaagtat atacagtata cttgaagcaa cgataaaaaa ggagtttacg ttcatgggca
    68941 cattcacacc acttatcttg ttttggtata tttacccggt aatcgttttg tttggttgcc
    69001 aatttcttgt aaaattattt tcgttaaatc gtcgttttaa aataaaagcc cctgatttgg
    69061 cgattccttt tttgtggggc ggtatgcatg cattgtctag aaatacaggg acaatttcta
    69121 tcttaccgtt tttctttatt tctgttttgc taatgggaat ttgtattgct gttttccaag
    69181 catattatta tgaagaaatt atttatccgc gttatttcaa gatgacttgg cgtttggttt
    69241 ttctgttgac aatcgtcttg tacgctgtct tgatcattgt gaacatactt tcttacctat
    69301 gaaaaaaata gaaaagctgt aaaaagtctt ttaaaaggct ttttgcagct tgatttttaa
    69361 aaaaatgttt atgaataaaa aaagttgttc ccggatttcc cagaaaaggt ggtagaaagt
    69421 gggggattgt ggtagactaa ttttagttag tggaggaatg ggggctttca atgttgatgg
    69481 gtgaattcca acataatatt gatgcaaaag gacgtttaat cgtgccctca aaacttcgtg
    69541 aagaacttgg cgaaaagttt gttctgacac gcggattgga tggctgtctt ttcggctatc
    69601 cgatgagcga atgggaaaat ctggaagcta aactgaacga aatgccgttg gctaaaaaag
    69661 acgcacgtac ttttgtgcga ttcttctatt cggctgccac tgaatgcgaa cttgataaac
    69721 aaggacgaat caatataccc agcacgttaa gaaattatgc agctttgaca aaaggttgcg
    69781 tagtcatcgg tgtatctaac cgaattgaaa tttgggatga gacacgatgg caagattttt
    69841 ctgcagcagc agaagagaac tttgacgaaa ttgctgaaag tatgattgat ttcggactat
    69901 aagaatagga agaggctgac taatgactga aacatttcaa cactatacag tcatgttgaa
    69961 agaaacggta gatggattga acatcaaacc ggatggcgtt tatgtagact gtacactcgg
    70021 cggtgccgga catagtgaat atttattaag ccaactaagt tctaaagggc atctgtatgc
    70081 gtttgaccaa gatcaaaaag caatcgatca cgccaagctg cgtttagctt cttatgtcga
    70141 acaaggtatg gtcacattta tcaaagcgaa cttcagagaa ttagaagaac gcttgagtga
    70201 gcatgtagat aaggtagacg gcattttgta tgatctaggg gtttcctctc ctcagctaga
    70261 tgaagcagaa cgtggattta gttatcatca agatgcaccg ttggatatgc gcatggatca
    70321 gtcagctcct ttatccgctt atcacgtaat taatgaatat tcctaccatg aattagtaaa
    70381 gattttcttc cgctatggcg aggagaaatt ttccaaacaa attgctcgtg aaatcgaacg
    70441 agtacgaaaa acaaaaccaa tccaaacaac tggtgagctt gtcgaaatca ttaaacaagt
    70501 catcccagct cccgcaagaa gaaaaggcgg gcatcctgca aaaagaattt ttcaagctgt
    70561 gcggattgca gtaaatgacg aactcggtgc cgaagaggcc tctttagaac aggcaatccg
    70621 gttattgaaa gtcaatggaa gaatcagcgt aatcacattc cattcattgg aagacagaat
    70681 tgtcaaaagt atgtttaaag aatatagtac ggtacaagat ctaccaccgg gacttcctgt
    70741 catacctgac gaattccaac cagaactgaa agtcattact cgtaaaccaa tccttccttc
    70801 agaggaagag ctaacagaaa acaatcgatc acgcagtgca aagttacgta ttgcagaaaa
    70861 aataagaatg aaagaggagt agaatgatgg cagaattaaa gaaaatgcaa gattacgaat
    70921 atgatttacc tgaattggtg gatcagccgg aacaacaaat gcctgattct tcttcgaatc
    70981 aagaaatcat tcttccacaa tcaccggcaa aacgattaaa gcagatttct gctttggaaa
    71041 aaattgctgt ggcaagcgtg gcgattgcta ttgttgcttt atgtgtttta acagttatgc
    71101 tgcgcacaaa tatcagcgga gctgaaaaag aaatcacgtc aatacaaaca gaaatcaatg
    71161 ataaaaagca agaaaaaacg agtttagaac aagaaaaaaa cgaactttct cgtactgaac
    71221 ggattaaaca aatcgcagaa gaaaaaggat tgtctattaa tgacgacaat ttaaggaaag
    71281 tgaagtaaat gagtcttaaa aataaaattc ggcggtttat ggaaaagaaa aatctaaatc
    71341 cgatgaacaa tcgcaaaaaa gtaggtatca ttttatttgc tacgagtatt ggaatgttct
    71401 ttttatttgc cgtccgtttc tcgtatatcg ttattggagg tcatgttgct ggtacctcat
    71461 tagctgaaaa aacaaaacag ttgtaccaag gaagtgaagt agtaaaagca aaaagaggaa
    71521 cgatttatga tcgtaacggt gtggcgctcg cagaagatgc ctcctcttat tcaattaaag
    71581 cgatactctc aaaaacatat acctctgggg ataaaaaact gtatgttgaa gaaaagaatt
    71641 ttgataaaat agcagaaatc ctgcataaga atctttctat agacaaaaaa gatgcactga
    71701 atattttaga ggacggcgca aaaaaagagc tgtatcaagt tgaatttggt agctatggga
    71761 aaaatatctc ccaagaaacc aagcaaaaca tcgaagcgga catgaaaaaa gaaggtgtcg
    71821 ctggtcttta ttttgtcgac catcaggctc ggatgtatcc aaatggcgtc ttttcttctc
    71881 attttattgg atacgcagtt ccagacaaag atgagaatgg cttagttggt aaactaggtt
    71941 tggagtctgc ttacaatgat atcttgagcg gtaaagatgg taagattatt tatcaaaaag
    72001 ataattttca aaatcctctg ccaggtacag tggcagaaga agaaaaagct gtcgacggac
    72061 aagatatcta cacgacttta gacagcagac tacaaagtta tttagaaaca ctgatggatc
    72121 aagtaaatga agaatatcag ccagaagaat tgacagcagt cctgatgaaa gcaaaaaccg
    72181 gagaaatctt ggcaatggga caacgaccta ctttcaatcc tgaaacaatg gaaggattga
    72241 ctggaaaaga tgctatctgg cgtaatttct tggtacaaga tagttatgaa ccaggatcaa
    72301 ccatgaaagt tttcactact gcagctgcta tcgaagaagg agaattcaac gagaatgaaa
    72361 ccttccaatc tggaaaaatc caagtagaag atgctacgat caatgaccat gactttggtg
    72421 aaaaaggtgt gctgaccatg cgtcaagctc tttcatggtc aagtaacgtc gggatggtca
    72481 tactggaaca gcgattaggc ggacgatggt ataactattt acaaaaactg ggatttggac
    72541 aaagtactca ttctggatta gatgatgaag taaacggtgc tttacctaca ttaaatattg
    72601 tcgaccgagc aatgagtgct tatggacaag cggtaggtgt gacgaatttc caaatgatga
    72661 aagctttcac ttctattgcg aataacggta caatgattca acctcgatat atcagcaaag
    72721 tggtggatcc ccaaactgga gaagagcgaa caactcaaac agaagttcta gggcaacctt
    72781 tttcaaaaga aacaacagaa aaagtccgtg aatatatgag agatgttgtc gaaagcgaaa
    72841 actacggtag tgcttatggt gtatatagtg tacctggata caatgtatcg gcaaaaaccg
    72901 gaacagccca aatcgcttct gatacagggg gatatcaaac aggagataca gcctacctgt
    72961 attcgattgt ggagatggtt ccttctgaag atccagacta tgtcttgtat ctaacaatga
    73021 aacaccctaa gacatatgat cgaatggcat tggctaaaat cgcaaatcca ttgatgaaac
    73081 gggcaatgga ttttaaagaa actgaagaag attcagatac agaaacaaaa acagaaaaag
    73141 tatccgtagc cgattatcgt aatcttgaag cggacgttgc agcagctgat gctcaaaaaa
    73201 gtggactgca acctgtagtg atcggtaatg gtaaaaaagt acaaaaacaa tctactgcca
    73261 acggtgatca gttgatctct ggagaaaaac tgatcctata tactggtggt gataagctga
    73321 tgcctgacgt aacaggatgg tcaaaagcag atatcatgaa gctggggaaa atcctcggta
    73381 ttgaagttag ttttgatgga gatggttatt gtgtcaaaca agaacttgct ccatatgaaa
    73441 aaatcactga agacaaactt agttttactt tagaagaata agaagagaaa taggagagaa
    73501 aagagcatgg aatggacaca agcattgatt cccattgtca gcagttgtgc aatgacaatt
    73561 gccgcaatgc cgctatttat tggttatttt caaatgaaaa agcaaggtca ggcgattcgt
    73621 gaggagggac caaagtggca caatagcaaa gccggaactc ctacaatggg cggcttagtg
    73681 tttctgatcg gctctatttt gacaggaatt tgggttggag cttggcaaaa acagctaact
    73741 cctactcttt tcatcttgct ttttgtatta gcgttatacg gagtaatcgg ctttcttgat
    73801 gattttataa aaatattcaa gaaaagaaac atgggactga actcgaagca gaaattgatt
    73861 ggacagattc tagggggaat catcttttat cttgtttacc gttctgaagg ttatccaggt
    73921 gtattgaatt tcttcggact agatctacct ttaggaatca tttatggtat tttcgctctc
    73981 ttctggcttg ttggattttc aaatgcagta aatctgacag atggcatcga tggattagtt
    74041 gctggcttag gaagtatctc ttttgcagct tacggtctaa ttgcttggca tcagcatcag
    74101 tatgatgtat taatcatttg cttaagtgtt ttaggaggtt tactgggttt cttcgtctac
    74161 aacagaaaac ctgccaagat ttttatggga gatgtcggtt cattagcgtt gggcggactt
    74221 ttagcggcaa tttctataat gctaaaccaa gaatggacat tgcttttgat tggtttgatc
    74281 tatgttatgg aaacagcaag tgtgatgctt caagttactt cctttaagct tacaggaaaa
    74341 cgaattttta aaatgtctcc aattcatcat cactttgaaa tgtgcggatg gtcggagtgg
    74401 aagattgata cagttttttg gttgatcagc attgtgactt cgttgatcac attatggatc
    74461 gtttggtagg agatgacggg aaatgaaaaa aatatcaaca tatgaaaata agaaagtgct
    74521 tgtcttagga ctcgcaaaaa gcggagtaag tgcggccaaa ttattacatg aattgggcgc
    74581 acttgtcacc gttaatgatg gaaaaccttt tgacgaaaat ccggaagcac aagagctgct
    74641 ttctttaggg ataaaagtaa taacaggtag tcatccaatc gaattgttgg atgaagaatt
    74701 ttcattgatg gtcaaaaatc cagggattcc ctacaggcat cctttagtag caaaagccca
    74761 agaaatgggt attccggtaa ttacggaagt tgagctagct tacgaagtag cggaatgccc
    74821 aattattggg attacaggaa cgaacggaaa aacaacgaca acaacgatga caggactact
    74881 actgaatgca ggagcagatc aaggaattgc acgtttagcg ggtaatattg ggtatccagc
    74941 aagtggtgta gcgcaagaag caaaatcaga agataaaatt gtgatggaat tgtctagctt
    75001 ccaactcatg ggaatcacag atttccgccc tcatatagcg gtgattacca atatctatga
    75061 agcacatatt gattatcatg gtacaagaaa agaatatgtc aaagctaaat ggaaccttca
    75121 aaaaaacatg acagaaaaag attatctgat ccttaactgg aatcagtcag aactacaaga
    75181 attagcgcaa agaacaaaag cacgcgtact gcctttctcg acaaaagaag tgttggaaga
    75241 cggtgtgtat gctgacgatt actcaatata ctataaaaaa gaaaaaataa tggaaatatc
    75301 tgaacttggc gtaccaggta agcataatgt agaaaatgca ctagctgcta tttctgtagc
    75361 aaaattgtat ggtatatcaa atgaagctat acgagaaacg ttgcattttt tccatggcgt
    75421 accacatcgt acgcaatatg taggagaaat ccaaggcaga aaattttata atgattcaaa
    75481 agcaaccaat attttagcga ctaaaatggc tctaagtgga tttgaaacgt ctaaggtcgt
    75541 gttattggct ggcggattag acagaggaaa tacatttgat gaattaattc cttcattaaa
    75601 aggaatcaaa gcaatggtcg tatttggcca aacaaaagaa aagttgatgg atgctggaaa
    75661 aaaagcaggc atcgagacaa tagtaacagc cgattctgta gaacaagcag ttcctttagc
    75721 attagaaaac agtacagatg gtgatgtagt tttattatca ccagcgaatg ccagctggga
    75781 tcaataccca aattttgaaa ctagaggaaa cagattcatg gaagctgtga accgattaaa
    75841 atagaaaaag tagaagcgag cgataaaaaa tgaaaatttt ggttacaggc ggaggaacag
    75901 ggggacatat ttatccagct cttgcctttg tcaattatgt aaagactcaa gaaccgaatg
    75961 ctgaattcat gtatgtggga gcaaaacgag gtctagaaaa caaaatcgtc cctgatacag
    76021 gaatgccttt ccataccttg gagattcaag gatttaaacg aaaaatttcc atgcataaca
    76081 tcaagacggt ccgattgttt cttaagagta tccgtcaagc aaaaaaaatc ctcagtgatt
    76141 ttcaaccaga tatcgttatc ggtactggag gatatgtttc cggagcggta gtgtacgctg
    76201 cagccaaaat gggtattcca acagttatcc atgaacaaaa cagtgtacca ggtgttacca
    76261 ataaattttt aagccgatat gtggatcgga tcgctctttc atttaaagat gcggcttcct
    76321 tttttcctga aaacaaagca gttcttgtag gtaatcctcg agcacaagaa gtagcagata
    76381 ctaaaaaatc agatattttg aaaacatttg atttggatcc agaaaagaaa acagtcttga
    76441 tttttggcgg tagtcaagga gcacttaaaa tcaatcaagc agtatcagtt tttttaagtg
    76501 aatatattcc ttcttcttac caagttttgt atgcttcagg agatagatat tatgaagaga
    76561 tcctaaataa aataaatcct gaaatacaaa atattagtgt ccagccttat atcaaaaata
    76621 tggcagaggt catggcttcc agtgatctgc tggtggggcg tgctggtgca acttcgatcg
    76681 cagaattcac agctctgggg ttaccggcag tgttggttcc cagcccatat gttacgaatg
    76741 atcatcagac taaaaatgca atgagtcttg ttcacgcagg agcagcaaaa atgattgcag
    76801 ataatgaact aacaggtgaa tcactaagtc agacagtcaa cgaaatcatg ggtgatgaag
    76861 aattgcaaaa gcaaatgtgc cgagcttcta aagaacaagg aatccctgat gcttcaaaac
    76921 gtctttatga cttagtaaaa caaataatca aaaaataaag gcggtggtct tagtgagtaa
    76981 gaaaaaagaa ccaaaaaaat tgtctcatcc gtcttctgat gaaaacaatt tgactccttg
    77041 gcaaaaggct aaccgaaaat atctggcaga acaagagatg aaaaaccaag agccaaaaaa
    77101 agaagacata acattagata cacccctttc agattctgaa gaagaaaaaa cggttcaaga
    77161 ggaacagcaa gaagaaagcc agtccgagaa aaaaatcgaa ttttttgaag agatcaagca
    77221 aaagaaaaac ggtggaccat ataacggttc ttttttgaac cggctgccca atttaaaaag
    77281 tcaacggcac aaagtactat ttcgtcggtt agctttgatc atcactgtat tgggtatacc
    77341 gctgattttt ttgatctatt atgtttctcc ttatagcaaa ttacaagcag ttgcagtatc
    77401 aggcaataag acagtcaaca gccaagaaat catctctgat acaaaattgt cattaggaga
    77461 aaatgtttgg ggacagtatt ttcatcgatc tacttatatc gatcgcctta aaaaagcaca
    77521 gccaagaatc gaaacagcaa atatacattt caaagggatg aatgaattcg atttggatgt
    77581 aacagaatat aaagagattg ctttgatcgc aaaaaacaat caatactacc cagtgattga
    77641 aaatggaaca gtattagatg aaaaagtagc aaatcctaca aaaaatctcc ctatcttgga
    77701 agagttcaaa gactctgcaa aaatcaaaga attaacaaag caatacaatc agttatcatc
    77761 agaattacaa aaagcaattt ctgaaatcaa gtacacgcca agagcaagca ataaaaatct
    77821 gatccaattg aatatgaatg acggcaatca agttattgta aatatcaata atcttgcgaa
    77881 ccaaatgaaa tattattcgc aagtagccaa agatatggat gaaaaaggtg tgatcgacat
    77941 ggaagttggt atcttctcgc atccttacgg tagcactcaa gaaacggaag aatcgggcca
    78001 atcggaagaa acaactgaaa gtgaagaaaa tgcggatcaa acaaacgaat caagtgaaga
    78061 ggcagaaacg caaaaagcac aaacacctgg atcgtctagc acaaacggat catctgattc
    78121 aaatgattca agtgaaacaa gtcaaataga agataatcca agtacaactc cgtcaagttt
    78181 aaatgaaaat tgataaaaca actttaaaaa gtaagaatgt actttctaaa aaccagtaat
    78241 ttatggtaga attggaagca gtgaatatat ctattaataa gtatatttta aaacggacgc
    78301 tagttgttcg cttgtatatg gaatagtaag taggagggaa tcccattcat ggcaaaaaca
    78361 ggaatgtatg taggccttga tattggaacg acatctgtta aagttgtcgt ggctgaatat
    78421 atcgacagcc aaatgaatat tattggagta ggaaacgcaa aatcagaagg gattaaccga
    78481 ggcattatcg ttgatatcga taaaacggtc caagcgatac aacgagcagt acgacaagca
    78541 gaagaaaaag caggtatcca gatcaaaggc gtaagtgtcg gtttgccagc aaacatgctt
    78601 gaagtagaaa attgccaggg aatgattgca gttaacggag attcaaagga aatcaccgat
    78661 gaagatgtca gaaatgtggc ttcagctgcc cttgttcgtt caatacctcc tgaacgtcaa
    78721 atcgtgtcaa tattgccaca agattttact gtcgatgggt tcgagggaat caaagatcct
    78781 cgtggaatga tcggcgtaag attagaaatg tacggtctgt tgtttacagg acctaaaacg
    78841 atcatccata acatacgtaa atgcgtggaa aatgccggat taatcgtcaa cgaaatggtg
    78901 attactcctt tagcgctgac tgaatcaatt ctttctgacg gagaaaaaga ttttggtacg
    78961 atcgtcattg atatgggtgg cggccaaaca acaacggctg ttatgcatga taagcaattg
    79021 aagtttacca atcttgacca agaaggtggc gaatttgtca ctaaagatat ctctattgta
    79081 ttaaatacgt catttaacaa tgcagaagcg ttgaaaataa actacgggga tgcataccca
    79141 gaacggacat caccagatga agaatttcca gtagatgtga ttggtcagtc agaaccagtg
    79201 aaagtcgatg aacgctactt gtcagaaatt atttcagctc gaatggaaca gattttcaac
    79261 aaagcaaaag atgcattgga ccaaatcgaa gcattagagt tgccaggtgg cgtcgtattg
    79321 acaggcggag ctgctagtct tcctggtgtt gtggacttgg cacaagaaat cttcggcgta
    79381 aatgtaaaat tgtatgttcc aaatcacatg gggctgagaa acccggtatt tacaaatgta
    79441 ataagtatcg tggattattc agcaaacttg agtgaagtgt atcaattggc aaaaattgct
    79501 gttacgggtg aaacctcagc agctcgtcaa atggtagttg aacaagaaac aacaaacaca
    79561 tatgagagct atgaagcacc tgaagaaaca atctacgatg agccggaacc aaaagagtcc
    79621 ggagaaaatg taaaaaataa aatcaagggt ttctttacaa atatttttga ttaattcatc
    79681 ctgggaggaa taagatatgg aattctcaat tgataataat atcaatgacg gcgcagtaat
    79741 caaagtcatc ggagtcggtg gtggcggtgg aaatgctgta aaccgaatga ttgaagaaaa
    79801 cgttaaaggt gttgaattca ttacagccaa cacagacgtg caagcattaa aaaattcaaa
    79861 agctgaaaca gttatccaat taggccccaa atatactcgt ggtttaggtg ctggttctca
    79921 gccagaagtt ggacaaaaag cggcagaaga aagtgaacaa tccttacgcg aagctttaga
    79981 cggtgcagat atgattttca tcactgcagg aatgggtgga ggaaccggta caggtgctgc
    80041 accaatcgtt gcaggtatcg cgaaagaatt gggcgcattg actgttggtg tcgtgacacg
    80101 tccattcact tttgaaggac cgaaacgtgg ccgttttgct gcagaaggta tcgctcgttt
    80161 gaaagaaaat gtggatacat tattaattat ctcaaataac cgtttattag aagttgtaga
    80221 taaaaagaca ccgatgcttg aagctttccg tgaagcagat aatgttttac gacaaggtgt
    80281 acaaggtatc tctgatttga tcacagcgcc aggttacgtt aaccttgact ttgctgacgt
    80341 gaaaacagtg atggaaaacc aaggtacagc attgatgggg atcggtgtgg ctagtggaga
    80401 agatcgcgta gtagaagcaa cgaaaaaagc aatctcctct ccattgcttg aaacatctat
    80461 tgatggagct gaacaagtac ttcttaacat cacaggcggt ttggatatga cattgttcga
    80521 agcacaagat gcttcagata tcgtagcaaa tgcagcaact ggcgatgtaa atatcattct
    80581 aggtacatct atcaatgaag aaatgggcga tgaaatccgt gtgacggtca tcgcaacagg
    80641 tatcgatgaa tcaaaaaagg aacgcaagtc tagccgacca gctagacaag cacaaatgca
    80701 atcacctgct caaaagactg tattagatat ggatcaagct aaaccaactt cttcagaaga
    80761 agaaaacagt tttggcgatt gggatatcag acgtgaacaa aatgttcgtc ctagagttga
    80821 tgattccaat tttgacaata tcgaaaaaaa agaatttgat acattcaacc gcgaagaaac
    80881 aaaatctcat ggcgatgatg aattaaatac gccaccgttt ttccgtcgta aaaaataaag
    80941 gagaggaaga gcacatgatt gctgacaact tgcagaaaat caagcaagaa attcaggatt
    81001 cgtgtgctct tgttcatcgt gatccgaaag aagttacatt agtagctgta acaaaatctg
    81061 ttgaatccgc tcaagctgaa gaattggtta gagctggcgt tatgaattgt gcagaaaacc
    81121 gagtagataa attattagaa aagaaacaag atttatttga ttttcctgaa ataaagtggc
    81181 atttaattgg taatttacag cgcagaaagg taaaattgat tgtaaatgaa attgattact
    81241 ttcatgcgtt ggacagttta agattagcag aagaaatcca gaagcggtta gagaaagaat
    81301 tatcctgttt tattgaagta aatgtttctg gtgaggaatc aaaacatgga atttcaccag
    81361 atgagctttt accgtttgtg gaatctttag ctgcctgcac aaaaatcaag gttgttgggt
    81421 tgatgactat ggcgcctaaa gaagcttctg atgagcaaat ccataaagtg tttggtacgc
    81481 tgaaagaatt gcgtgatctt gttcaagcaa aaggttatgc ccatgcacca tgtagtgaat
    81541 taagtatggg gatgagtcaa gactttcaaa ttgcgattga agaaggtgca acatttatcc
    81601 gtgtaggaac agcgctattc aaagacgaat aaaggaggaa caaaaatgcc gcttttaaac
    81661 agaggagcaa ttgctaattt tttcggatta gctgatgagg aagagtacga ataccaagat
    81721 tatcctgaaa caacaaaaaa ggctgtacag ccaactaaaa aaaatacaac acagaatcaa
    81781 tcaactcatt ctgtatctgc tgcgaatact catgaaaaac aaaaaacggc gacttcacgt
    81841 cctgtaacgc atgaaagtat tcagccggct gaaaagaaaa aagtaattga actacatcaa
    81901 tcacctacaa aaactgtagc gaaagaaaga acagcttcaa gaacctctac acaacctaaa
    81961 gcaaatcttg ctggaaaaat cactgtaatg gaaccaagag cttattctga agctatggcg
    82021 attgctaaac gaatcattgc tggagaagca accttagtga attttcattt agtagaagaa
    82081 aaacaagcga gaagaatcgt tgattttcta acaggaacag tttatgcact agatggagat
    82141 atcaaacgtg ttggagatga gatttttctt tgtacaccga ctgggatgga gattgacagt
    82201 tcaaccgctc aatcttttgc agatgcgaat ttgtttgatc tgtaagagga ggaactacga
    82261 tttatactat tgcactatta cttcatttac ttcaacgggc agcctatttc tatagcatta
    82321 tcttgatggt atatgcattg ctctcttggt ttccaggcgg gtatcaatca gggctaggac
    82381 gattattagc taagatctgc gaaccgtata tcagtttgtt cgatcgtctg cctttgagga
    82441 ttggaccctt ggatttcaca attttagggg caatcctgat cttgaactta gccgtacaag
    82501 gtttagcaca gatcgttata tggataactg tccatttagt ttattgattg aagcaacaaa
    82561 atctttattc tcagaataga taggagggga aaattttgga tgcaaatgta taccagcact
    82621 ttcgggcaga tgaacgtaca tttatcgatt cggtaggcga ttggattgaa caggttcaag
    82681 gacaatatgc accctatctg accgaatttc ttgacccaag acaatcctat attttagaaa
    82741 cactgattcg acaaagcagt gatttgcgtt tcatgtttta tggcggatat gaacaggcag
    82801 aaagaaaaag atgtttgatt ttccccgatt attacgaacc tgtagaggaa gattttgaaa
    82861 cagcattgta tgaaatccat tatcctagca aatttgccag cctaagtcat gggaaaatcc
    82921 ttggaacttt agtgggaacg gggatcaaac gctcttactt tggcgatatc atctcggacg
    82981 gtgatcgctg gcaagtattt attgcaaatg aggtggatca ttttgttgct gcacaagtaa
    83041 caaagattgg aaaggttgct gtacgcttgg aaccaatcaa atacacagaa atgattatgc
    83101 cgaaagatag ctggacacaa gaaagaggaa cagttagttc catgcgacta gatagtgtga
    83161 tctctgagat ttataatatt tccagacagc ggtccaagca gctgatcgaa gctggtaaag
    83221 taaaagtgaa ctggacagaa aatacaagac ctgattttgt acttgaacta ttagatatta
    83281 tttcagtcag aggttatggc agagtccaga tccaagaact tgaggggaag acgaaaaaag
    83341 aaaagtacag ggtactgttc ggtgtattac gtaaataaaa taaaaaggtg gtttactcat
    83401 ggctttaact ccattagata tccaaaataa gacattcccg acaaaaatgc ggggatataa
    83461 tcaagacgaa gtagatgatt tcttagattt agttgttcgt gactatgagg aattgactca
    83521 aagaaatcga gaattagaaa aagcagtcaa acattctgaa gaaaaacttg agtacttcaa
    83581 tgaattaaaa gatgctttga accaatcaat catcgtagct caagatacgg ctgataaagt
    83641 aaaaacaagt gcaagcaagg aatccgaagt gatcgttact tctgcacaaa acaaagcaga
    83701 tgagttagtt gcgaacgctg aaaaacgtgc acatcaatta acaactgatg cagaagaaaa
    83761 agcaagaaaa atcttgacag atgcaacaga aaaagcaaga cagcttgcga cagaaactga
    83821 agatcttaag aaaaaaacac gagtattcca tcaacgtatc agcttgatgc ttgagtctca
    83881 attagaacaa gtgaaaagtc cggaatggga tgaaatttta caaccattct ccagctacgt
    83941 gactgacagc catgaagtga tcaaagaagt tttagcaaaa cagcttgaca atgaaaatga
    84001 tactgatgta aactcagaca caggagtcat agaagcacct atgacggcat ttgatacaca
    84061 ggctattgat atctcgatcg tgcctggtga aaatgaaaac gagtagaaca gaaaagcact
    84121 ttgttattct taaagcgagc cgatgagagt ggaagttcgg taagacactg catggtgaaa
    84181 gatcctctac ttgagacctg cttttccgaa attagagtaa gaagcagcgg ctgacctcgt
    84241 tattggtcac agagagtttg cactagatag atgcaactaa atttgggtgg taccacggca
    84301 tgttcgtccc ttgcggctga acatgctttt ttgtgtccgg aaaacaaata aaggagtgta
    84361 tggttgaatg aaaatgaaag aaaccttgca attaggaaaa acaaaattcc ctatgcgtgg
    84421 taatttgcca aaccgagaag gcgagtggca aaaagaatgg gaagaaaatc gaatctacca
    84481 aaaaagacaa gagttgaacg aaggaaaacc tagctttgtt cttcatgatg gacctccata
    84541 tgccaatggt aatatccatt taggacattc attgaataaa atcagtaaag acattatcat
    84601 tcgttcaaaa tcaatgtctg gctatcgtgc accatatgtt ccaggatggg atacacatgg
    84661 attgccgatt gaacaagtat tggctaataa aggcgtgaaa cgtaaagaaa tgtccatggc
    84721 agaatacttg gaaaaatgtc gtgaatatgc actttcccaa gtagataagc aacgagcaga
    84781 tttcaaacgc ctaggagttg caggagattg ggaacatcct tatgttacat tagatccttc
    84841 ttatgaagct gcacaagtac gcgtatttgg taaaatggct gaaaaaagct atatttacaa
    84901 aggattgaaa ccaatttact ggtctccgtc aagtgagtct tctttagcgg aagctgaaat
    84961 tgaatataaa gatgtaaaat ctccatctat ttttgtagct ttcaatgtca aagacggcaa
    85021 agatattctt gatgaagata cagcttttgt catttggacg acaacaccat ggacattgcc
    85081 agcaaaccaa ggtattgctg taaatccaaa atttacgtat gtattggtgg aagccgatgg
    85141 ccgtaagttt gtcgtagcga aagatttgct agaaacagtc caatcagaaa tcggttggga
    85201 aaatgtaaca gttctaaaag aatttgctgg acaagaaatg gaatatatga ctgcaagtca
    85261 tccattctat gaacgtgaat cacttgtgat tttaggcgat catgttactt tagacgctgg
    85321 tactggatta gtccatactg ctccaggaca tggggaagat gactatatcg ctggtagcaa
    85381 atataaacta tctgtagtgt cacctgtaga ctcaaaagga ttgtttacag aagaagcacc
    85441 tggatttgaa ggtatctttt atgacaaagc aaatcctatg atcactgatc tattaaaaga
    85501 aaaaggagct ttgctgaagc tagatttctt tactcatagt tatcctcacg attggcggac
    85561 gaaaaagcct gtgatctatc gggcaactcc acaatggttt gcatctatcg ataaattccg
    85621 tcagaatatt ttggatgaag tagaaaaagt agcgtgggtt atcccatggg gtaaaacacg
    85681 tttgtataat atgatccgtg accgcggcga ttgggtaatt tcccgtcagc gtgcatgggg
    85741 agtaccactt ccgattttct atgctgaaaa tggagaagca atcatcacac cagaaacaat
    85801 cgaacatgtg gcaaaattat ttgctgaaca tggatcaatt atctggtttg aaaaagaagc
    85861 gaaagaactt cttcctgaag gatttaccca cccaggttct cctaatggcg aatttacaaa
    85921 agaaaaagat atcatggatg tctggtttga ttctggttct tctcatgaag ctgttttacg
    85981 tcagcgacca gaattatcat tcccagcaga tatgtattta gaaggatcag accaatatcg
    86041 tggctggttc aactcaagta tcacgactag tgtggctatc aatggtgtag caccatacaa
    86101 atcagttatt tctcaaggat ttgctttaga tggtgaaggc cgtaagatga gtaaatcttt
    86161 aggaaacatc attgcaccag aaaaagtgat caaacaattt ggtgcagata tccttcgctt
    86221 atgggtatct agtgtagatt atgaagcaga tgttcgtgtt tctatggata tcttaagtca
    86281 agtggcagaa gtatatcgta aaatcagaaa tacgatgcgt ttcttattag cgaatacaga
    86341 agatttcgat cctaaaaaag atactgtttc gtacaatgat ttacgttctg tagacaaata
    86401 tatgaccgtt cgattgaacc aagtaatcaa agaaatccga gaagaagggt acgacaaata
    86461 taacttcatg catatttacc gtacagttat gaacttcttg acggttgatc tatcgtcatt
    86521 ctacctggat tttgctaaag atgtagttta tattgaagca gaagatgatt atcaacgtcg
    86581 ttgcatgcaa actgttttct atcaaacagc tgtagctttg acaaaattat tgactcctat
    86641 cattccgcat acagcagaag aaatctggtc attcctgaaa gaagaagagg agtacgttca
    86701 gttaagcgag tttcctggtt atgaagagtt tgcaaaccaa gaagaattga tggatacctg
    86761 gactgctttc atggacttcc gtgataatgt cttaaaagca ttggaagaag caagaaacag
    86821 caaattgatt ggtaaatctt tggaagcaaa actaactgtt tatccaaaac aacaagttcg
    86881 tgaaatgtta aaagctttgg atgcagatat tgcacaatta ttgatcgttt caccagacta
    86941 ctttgaagtt atggcagcag atgaacaagt gccagataac gctatggtat ttgatgatgt
    87001 tgctattaca gtggaaaaag cagacgggga aacttgcgat cgctgtcgcc aagttcgtaa
    87061 agatgtagga gtagatgaaa aacttcctca tctatgcggt cgttgtgcaa aaatcgttga
    87121 agacttctat cctgaagctg tagctgaagg attcgaagaa aagtaaaagg gaaaaggggg
    87181 tgtgacatgt tctttgtcac accccctttt gttatcaatc gtttaatttt ccacgttcac
    87241 gataccagtt atctggttgc cagatccatt cgaatccgtc tttttcaagt agttcgaaag
    87301 ctgctttagg tcccattgat ccagctttgt agttgggaaa atccggttgt gtttggtccc
    87361 aagcttttcg aatgacatcc acgatatgcc aagattgagc gacttcttcc caatgagaga
    87421 agttcgttcc atcaccattc aacgcatcta atagtaattt ttcgtaagct tctgggctat
    87481 tttcaaccat ttctgcacta tttctaaatt ccaatttgat tggttccgtt tcaaatcctt
    87541 gccctacttc tttcccattc aaggataaag aaaatccttc agttggctga atatagatcg
    87601 ttagaacatt aggtggaagt gtcgtatcgt cacatggttc atcgacagat gttttgaata
    87661 cattaacagg aacttgtttg aatacgatgt tgatccgagt ccctttttca gtcaaacgtt
    87721 tgcctgtacg tacatagaaa ggaacacctg accaacggaa gttatcgata gtgaatttgc
    87781 ctgcgacgaa tgtttcagtc tctgattgag catccacttt gtcttcttcg cgatagccct
    87841 tgaattgtac accatccaat tcaccttgag catattgccc gcgaacgaag ttttctaaca
    87901 cttcttcttc gttataaatg cggatagctt tcaatgcttt gatcttttct gtacggattt
    87961 ctttttcgga aaatgctact ggcggttcca ttgcaagtaa tgctacaacc tgtaaaatat
    88021 gattttgcac catgtcttta agtgcgccac tatgatcgta gtagcccccg cgatcttcta
    88081 caccgaggtt ttcgccaaaa gtaatttgga tattgtcgat atagcgattg ttccattgag
    88141 cctcaaaaat attattggca aaacggatag ctgagatgtt ttggatcatt tcttttccta
    88201 aataatgatc aatcctgaaa atatcttgtt ctgggaatac ttctctgatt tgctggttca
    88261 attcaaaagc agactggtaa tcagaaccga acggtttttc tatgatcaaa cgattgaagc
    88321 cattttttgt cataatattt tgtgatttca aatgagaaac gatcgttcca aaaaattgag
    88381 gtgccatagc caaataatag acacggttac cgtttaattg atagtgtcca tctaatcggt
    88441 cagacaattc ttttaatgtc tgataatgcg ttgaatcatt tacatcatgg gattgatagt
    88501 aaaaatggct tgcaaaggta gttgcttctt catctgaagg attcaatgca cggattgttt
    88561 ctttgacaac ttcacggtag tgctcatcgc tccagggacg gcgagcggtt ccgattacag
    88621 caaaatgctc gcctaaattt ccttttctgt aaaggcggaa caaagacggg tacaatttac
    88681 gctgggctag gtcacctgta ccgccgaata tcgtaaacaa tacatttttt tcattagaca
    88741 tgtggataca ctcctttata ttttatcgac aaaaatcgtg ctggccgcct taaagctgac
    88801 ggggattttc tttctatcat tttggatagt gatcggtcct tcataagctg cgatgtcaac
    88861 gatctcatat tcttcgttga tattcaggtc aatagtgact aagtaatcca acaattcttt
    88921 ttcatcaagc actcgtgcga tacgcacttt tgtaccgaca ggataggact ccaatgtttg
    88981 tcggcgttct tcatggacaa cttcctcttt tttaggaatc gatcctccat gaggacaatg
    89041 ttcaggatga ttcaaatagt tttctaaatg atctgcaaga tgttccgaag tcacatgttc
    89101 caatacttca gcatcatcat ggacttcatt ccagctatag tctaaatgtt caactaaaaa
    89161 aacttcccat aagcgatgtt tgcgaatcag actgctagct ttttgcagtc cgcttgcagt
    89221 caattgtaca ccttgataag gggaatgttc tacaagctct tctttcacaa gtttagaaat
    89281 catttcactg acagatgcag ctgagacatc tagactagat acgatttgtt tattgttgac
    89341 tttcgttgta tctccaccta gttctaaaat gattttcaaa taatcttctc gatttggtgt
    89401 catattcgat catcctttca tggtaaaaaa ccatcattag taagtgtaac aaaaaaaacg
    89461 ttaattgact atttttctaa ataaaaaaca aaggattttt agacgttttt acaacaaaaa
    89521 acgaaagatg atagagaaga ctcattcttt cgtttataaa ggatatatat atacattggg
    89581 agggatctat ttttcagata acaacttata tgaagtgtct gcagattcgt cataaagagt
    89641 ttgttcggga taagaaaaga taagataaaa accatactga tcacgtacga ctaaacgata
    89701 ttcatctatt tctaccacag atgtgccaag agactgaccg ttgatcaaaa acgtgtaatc
    89761 agatgtaatc tgtaattgtt gtttttgctg gctatcacta aagaaccatg taccttgata
    89821 ctttgagagt ccttctgact tttccgcttg ttttttcttt ttcaagtaaa taaaacttga
    89881 gagaacggta atgagtgaac caagaaaata gatcattttt tttatcacca aatcactcct
    89941 ttatgagaaa ataatcgcat agacatattc tttcttcttt atttcattgt accgaataaa
    90001 agctaaaatt tctctaagac tttcgactgg tttttttact gtttttctac aaattatgat
    90061 aggatacata gtaggaagaa aggtgacata atttgaagta tcagcaagtg gaaatagctt
    90121 tttttattga ccgcccgaat cggtttatag cacattgtat gaaaaaagac ggagaaataa
    90181 ttattgcgca tgtcaaaaat acaggtagag gaaaagaggt cctgatacca ggcgctgaag
    90241 tggctattgt atttgctcct ggacctaaac ggaaaaccgc ctatgatctg attgctgtaa
    90301 aaaagaaggg tgactggttt aatatcgata gtcaattgcc taatcggctg gcaattgatg
    90361 gtattttaga cggcacgatc cttttaccag gattaactgg tccatttacg gtatacaagc
    90421 gtgaagtaac ttatcttcac tccaaatttg atatttattt agagacggtg gtcggacaaa
    90481 aagcatttgt tgaagtcaaa ggtatgacac ttgaaaataa agcgattggt gcttttcctg
    90541 atgcgcccac actcagagga ttgaaacata taggagaatt aacgtatgcc gcacaagatg
    90601 gttatgccgc ttatgtcttg tttattgctc agttcgaaca tcttcatctg gcaacgatcc
    90661 atgaagaaat gcaaccagca ctagctgata tggttcgaca tgcgcagcaa agcggagttc
    90721 aaatcctcgc ctataattgt caagtatcgg cagatgaggt aactgtcaag caggccattc
    90781 catttgatgt agatatccct tttgaagatc ctatacaata gaaagaaggt aaaataatga
    90841 tcaacttagg tattatcgga acaaattgga ttactcatca atttgtccaa gcagctttaa
    90901 gcacaaaaaa atatgaattg acagcggtat attctagaca tttggaaaaa gcacaggaat
    90961 ttggttctca ttatgaaggg gatatcgaat tcgcaacaga tttgaagact tttttcaata
    91021 ttactcatat ggacaccatt tatattgctt ctccgaatag tcttcacttt agtcaagcta
    91081 agcaagcaat tttggcagga aaaaatgtga tagttgaaaa gccagctttt tcgacgccaa
    91141 aagaaatgga tgaaatcatc catttggcaa atgaacacaa tgtgtatttt tttgaagcag
    91201 caagaaatat ccatgaatca ggttttaaaa agattgccga ttacttacca ttaaaagacg
    91261 agataatcgg tgcaaatttc agctatatga aatattcttc gcgctatgac caagtattag
    91321 atggagaaga accgaatatc ttctcgactc atttctcagg tggtgcattg atggatttag
    91381 gtgtttacct tgtatatgca gctgttgctt ggtttggaat gccaaaagaa gtccattatt
    91441 tcccaagaaa gatttctact ggtgtagatg gtcttggatg ggggatctta cgttatgaga
    91501 attttgatgt atcgatccag ccaggtaaaa tcggtgattc ttatttaccg tcagagattt
    91561 attttgactc aggaacgcta gtgatgaatg gagtcaatgc aattgaacaa gcacaatttc
    91621 atgatcgcgc gcataaagaa atcattgatt tggcggtaac agctgcagaa aatccaatgg
    91681 cagatgaagc agaggatttt gccaatgtca tggctcatcc gaaagatcca gcttggggat
    91741 tgttgtatga agagtggatc gagctagcta gaaatgtgaa ccaagtgatt tatgatttaa
    91801 gaaaaaatgg cggcatcaaa ttcgatgcag ataatgagga agatttttaa tgaacgaatt
    91861 tgtacaagta tttcccgaaa attggcagaa aaaatatgag gataaagggt ttatctcacc
    91921 ttctcttatt caacgagcag tttttcagcc actaagtaat aaacaaagta tagtagcggt
    91981 ttctcctaca ggttcaggta aaacactggc ttatctttgg cctctactac taaacgtgga
    92041 accaggtgaa gcaagtgcgt tggtcatttt tgcttcttct caagaactag ctattcaagt
    92101 agcagatgtt gcacgtgaat ggggaaaaga caaagagttg aaagtccaat ctttggtggg
    92161 cggagccaac gtcaaacgtc agattgaggg tttgaaggaa aaaccagaaa tcttgattgg
    92221 tacaccagga agaatattgg aattgatgaa agcaaaaaaa ataaaagcac atcaagtgaa
    92281 aacaatggta tttgatgaag cagaccagct atttgacgct gggaacagcc aaatcattga
    92341 tcaaattctt catcaagctc caacagagta tcagctagct tttttttcag cgacagcaga
    92401 tcgttccctt gaaagcattg aaaaaatcac tgggaaaacg tttgagacaa ttgacgtgac
    92461 agcagaggac gattctcgaa aaggactgag acattacttt ttacgtgtac cgatacgaaa
    92521 gaaagatgac tacttgagac gtctcacgca tatagaagat tttcatggtc tgattttctt
    92581 taatcaactg actgaattag gcgtaatgga agaaaaattg ctgtatagag gtgtaccggt
    92641 aggaagtctg gcctctgatc agaacaagct actccgaaaa gcagcgctag aacaattcaa
    92701 aaagaaaatg gtcagagcac ttttgaccac agatgtggcg gctagaggtt tagatattac
    92761 aggtcttcct tatgtagtga atgcagaagt tccgttaagt gaagaagctt atttgcatcg
    92821 ttcgggaaga actggtcgaa tgggtaatga aggaatagta attacactcg tacaagataa
    92881 taatctaaga gatttaaaac ggcttttacg tccatcaaat ataacacttg aagagatttt
    92941 tttatacgga ggtaagctgc aaactgagca gccaaccaaa gaagatgcag ctcctgcagt
    93001 aaataaaaag tatgcgaaaa ctttttctgg aaaggagcag aacccagaat ataacaaaga
    93061 aaaaataaga aaaaaagtta aaaataaatc aaaaaaagag agaaataaag gagcaaggcg
    93121 caaataagcg cctttttatg ctatgattat gaaaacggga acaaaattgg ttgccagagg
    93181 aggggttatg tgaaagaacg tcaagaagag atcttgcagc tattgacaga aaaccaacaa
    93241 ggattgacag caagtgatgt agctgagcgc ttaactatcg atcgaagcaa tgcaagccga
    93301 tatttaagtg aactatacaa ggcccatcat attgtaaaaa ccgctggccg accagtcgtt
    93361 tactctttgc caacggaaaa gtcaaaatct gatgaagtgc atgtcgactc ttctacgcaa
    93421 gtgacttttg aaacactcgt tggagaaaat gattctttaa aagtcagcat acagcaggca
    93481 aaagctgcga ttctttatcc accgcggggg ttgcatacga ttatttttgg agaaactggt
    93541 acagggaagt cgatgtttgc tgaatgtatg tatcattttg caatcgattc agagatgctt
    93601 tctgcagatg cgccatttgt ttctttcaat tgtgcggatt atgctcaaaa tccgcaactg
    93661 ctctttggac acatctttgg gatcaaaaaa ggggcttaca caggagcagc tcaagatagt
    93721 cccggtctaa tagccaaagc agacggcggt atattgtttt tagatgagat ccaccgttta
    93781 ccgccggaag ggcaggaaat gctgtttact ttcattgata aaggtattta ccgtccgctt
    93841 ggagaaagtg cacaagtaca tgaagcatct gttcagatca ttggggcgac gactgaatct
    93901 tcagaaagtt tcttatctac gttcaatcga cggattccta tggcaatcac cttgccgaat
    93961 cttgcttcac gttcactgga tgagcgttat gaaatcatct ctctttttat caaacaagaa
    94021 gcgaatcgtt tgaatcaacg tatcgatatc gaaaaagaag cgattcttgc cttcatgctt
    94081 tatgatgcgg aaggaaatat cggtcaagtg aaacgagact tgaaactagt ctgtgcaaaa
    94141 tcttttttac attaccgtac tcatcatgag aaaaagctaa tcattcgaaa agaagaactt
    94201 tcccttcaag tacaaaaagg attactgaaa atcaaggaaa taccggaacg tctcgaccga
    94261 ttcatggaca gcaaaagtca gtatttgaca tttgaaccag gatttgctga tgttgtctgg
    94321 tcacaagatc cagaacgaaa catgcaggtc tataacgata ttgaggaaaa agtcacttct
    94381 ctttccgaaa ccggtgtgga gaacattgat ctagagaccc tcatttcaaa agatgtggat
    94441 gcttatttcc agacatatgt caaagaattg actaaaagtt cgattcccaa agatcttttg
    94501 ccagatgaaa tctggcggtt aaccaatcaa ttgtatgatg tggctgaaaa acggttagac
    94561 cgtatttata atgaaaaagc tcgttttgct tttgctttgc atctgcaaag tacattggat
    94621 cgtgtgagag aaggtcatat gatcgtccac ccagatttga ataacgtacg gaaaaatttt
    94681 aagagggaat tccaggtagc aatcgatctt tcaacgatca ttgaagaaga agaacaagtt
    94741 gagattcctt ttgatgaaat cggctttatt agtatgtttc tttctatcaa tctaggagaa
    94801 agtgagcctg ttaaagaaaa caaagtagat gttctcatat tgatgcacgg cagacagact
    94861 gcttcaagca tgttggagat ggcacaagaa ctattaggaa caaaagtagg gaaagctttt
    94921 aatatgccac tggttatgga agttcaaaca atgtatgaag aagtgttaca atatgtcaaa
    94981 aactatcaag agcatttgac gaatggccta ctcttgttaa cagatatggg atcattaaac
    95041 accttcagtg atttgattta tgaagagact ggcattcgga cgaaagctat cacgatgaca
    95101 agtaccatga ttgtgataga agcgatacgg atggcaagtg ttggaagaag cttagaagat
    95161 atttatcaaa atatccagct ttcctttgaa tcgatcgtac gtgatcagtt caaagcggaa
    95221 aagtctgaaa ctttacagcg taaaaaagcc gtaatcgtga catgctttac tggtgaagga
    95281 gtagctgcca aattatatca gcgtattatg ccagtgatta atcaaaataa ggtagaactg
    95341 atccagatgc agtttttaga acgtgaatca ttcaaaaaac acatcgatgc cttattggaa
    95401 gaatatgaga tcaaagcaat tgcgggaaca gttgatgttg attatcaaaa tatcccattt
    95461 ttttcagcct atgacgtttt tgatgatgaa aaactaaata ttttaaagcg tatagctgat
    95521 gatgagatcc cgacagctaa aattgtcgat tcacttgctg gatcattaag cgatgtcttt
    95581 tctattgatg aactgatccg ttcattgcaa aagacagttc agcagatcca gaccgatttg
    95641 tcgattatcg tggaacctgg agtagatact ggaatcgtta tccatttagc cttcatgtta
    95701 gacggattga tcaaacaaga aagccatcgg caatttgaga aactgtctat tttctcaaaa
    95761 atttatcgtt tggaaatgga tatcgttcgg gcaaacttga tggcactaga acgaaaatat
    95821 caggtaaaaa ttccagaaga tgatatcgca tttcttacac aaatgtttct tgaaaataaa
    95881 ataaaaaaat gaacacacta atcatactgt ttacacacta aacatctgtg tgcgcactat
    95941 aaaaaagagc taaaaagcat gaaaacgcta tttcagctct tttttttatt ggcatgcttc
    96001 ttgcgttata taaaagtgta aaaaaataaa aggagtgtta aaaatggcaa aaaaaacaat
    96061 catgttagtt tgttcagcag ggatgagtac gagtttattg gtcacaaaaa tgcaaaaagc
    96121 agcagaagaa aaagggatgg aagccgatat ttttgcggtc tctgcctcag atgcagataa
    96181 taatttagaa tctaagaatg tcgatgtatt attattaggt cctcaagtac gtttcatgaa
    96241 agctcaattt gaacaaaaac ttgcgcctaa aggtattcca ttagatgtca tcaatatgca
    96301 agactatggc atgatgaacg gagaaaaagt tcttgcacaa gcagaaaatc taatgaaata
    96361 aatcaagtat gcagttgggg gtataacaac gtggaagatc aacaaaatct agaagccatc
    96421 atggggttaa tcatgtttgg cggtaatgca aagagcgatg caatggaagc gattgcggct
    96481 gctaaaatcg gtgattttga gttagcggat aggaaaatcg ctgatgcaga agaatcactt
    96541 atacaagcgc atcatgcaca aacagacatg ttgacacaag aagcacaagg aaatcatatg
    96601 caagtgacat tattgactgt tcacagtcaa gatcacttaa tgacatctat tgcgtttact
    96661 gatttagcaa aagaaatcat cgaactttat cgtcgcgtat acagcgaata aatacaactt
    96721 cttttttgaa cggaagaaga aaaatttttg aacggatttt ttattttgtt ataaggagaa
    96781 ctctctttat ataaaaaact tataggagga agtaaaaaat gaacggacta tcaagttgga
    96841 tggagaaata catcctgccg gttgccgcaa aaatcggagc gcaaaaacat ttagttgctt
    96901 tgcgtgatgc ttttatcggc acactgcccg caacaatggc gggatcagtc gctgtaatga
    96961 tcaatgcaat tattcgtgat ttaccgcaac agtttaacag tacctatgct gacagtttag
    97021 cagcagacaa aggaatcttt gccgtattga atgtcatcat cggaatcaat ggttttgtct
    97081 ggaacggtac actagcaatc gccggattga tctttgcctt ttcttggggg tataatcttg
    97141 cccgagctta tggagtaaat gatctagctg gggggatcgt tggtttagct accttgattc
    97201 aaggtatttc ctttggtcca gcattatcag cagcattaga tgtgaatgtt ccttcaaatg
    97261 tcgcagatgc aatcaatagt tctgagattg gtgcaacgat tgcagatggc acactgtcag
    97321 ttggattatg gggttggcta aaactagatc atttgaatgg aaacgcttat tttacagtta
    97381 tgatcatggg agctatttca gtcattattt tttgtaaatt gatgcttgcc aacattacga
    97441 tcaaaatgcc tgattcagta ccaccagcag tatctaaagc atttgcagcc attttaccag
    97501 cgacgatcgc tttatacgtc attgctatta tcaattatat cgtaggtcgt gtagctgatg
    97561 ggcaactgat cattgatttg gtgcaaaaat atattgcaga accattccta ggattatctc
    97621 aagggttggg agcagtattg atcgtcacag tatttgttca agtattctgg ttctttggta
    97681 ttcatggacc aaatgtattg gcaccagtgc tagagggaat ctggggacaa gcacaactaa
    97741 tcaatattga tattttccaa aaaggttata acggaaaaac tggtacacca gccgtgttag
    97801 atgcaatcga agatggaaaa gcttatatgt gggtccgcgg atcgttcgat gcttttgcat
    97861 ggtttggcgg atcaggcgga acgatcgtct tactgatagc tatcttgatt ttctctaaac
    97921 gtgcagatta tctaacagta gctaaattat ccattgggcc tggtatcttc aatatcaacg
    97981 aaccagtgat gtttggtctg ccaatcgtat tgaatgcaat catgtttatc ccattcttga
    98041 ttgctccagt agtagcaaca gcaattggat ggacagctac ttatcttggc ctagtcgctc
    98101 cggtatcgca gcaagtcaca tgggtagtac cgccgttctt attgtcattc ttagcaacag
    98161 gagcggattg gcgggcaccg atcgtaacat tagtatgtat ggtcgtgact ttcttgattt
    98221 gggcaccatt tgtcatctct gcaaacaaaa tggaccctgc cgcaggcgaa caacaataag
    98281 atgaacgtga ggagcgggac gctttaagtt tcgttcctca taatgaattt tcgaggagga
    98341 actgaaatga ttacaattgc cagtgcaatg caacaagatg aaatcaaaga attgttagaa
    98401 ggatacaatg aagaaggaat gacttttaca tttaaagaaa aacaaggaat caagctgttc
    98461 tttgaaacaa gtgcagaaga tccggaagtt gcggctaaaa aagcaaagga actaatcaaa
    98521 gcacagcctt ggggaacagt cctttatttt caatcaacag ctgtttagaa aatggtttaa
    98581 aaagatagga tggttgagat gataaaaaac ggtttatttt tatgtagtat tggttctttg
    98641 atcgtgttgt atagtttgaa tccacattcg caaaggtatg atttgtatag tatggtcaca
    98701 ggtctttttc taacaggatt aggaatctat ttcttcatga aggggaaaaa aagagaagaa
    98761 gcaaaggaga aaaataacta atggaaatca cgaaaaaatt aaatattcca gcatcgtttt
    98821 tttacgataa agttatggac tctgtccttt tcgatgtacg taaagcgacc ggcaaatcag
    98881 taactagaaa acagctgaaa aatttggagt acgtcaaaca attctcgcaa aataaccggg
    98941 ctcgcataaa aatcgaagaa gtcattgaaa accagtctta taagtttcgt acatcgacaa
    99001 cgaagaatga attcgtcgtt cattatcaaa tcaaaccatt ggacgattcg acctgtgagg
    99061 ttcattacac agaaaaaatg gagtcttatg gcatgcttca aaagttgaat gatatgcttt
    99121 taggaacaat cttgatgtat tttaaacgga gacgtttcaa aaaaatgcta gatatgatcg
    99181 aagcaacgta ttaaatcaat gaaacatggt actatttagt tattgaaaaa tgaagtaagc
    99241 tagaaggaat ttttcatagg aagatagatc tttcctgcga atcctcacta gcttttttgt
    99301 aggaaggggc agcaaaatga caaacaaagt aagagagcta ggtgtatctt cgattgagga
    99361 aatgtttgat ttagccactt atgcatttaa tggggcagat acacctgaaa ggcgagaacg
    99421 ttttcgtaca cttgcggaga attcttggaa ttacggattt tttgatgagg aggatcggct
    99481 aacaagtcaa gtcatggcga ccccttttcc agtgaatttt tacggacaag agtacctaat
    99541 ggccggcatt ggctatgttg cttcttatcc agaagcaagg ggacaaggcg ggatcaatca
    99601 gatcatggaa aagatccttg aagattgccg tgatcgtaaa gtaagcttat cttatctggc
    99661 gccattctcc tatcccttct atcggcgcta tggctatgaa caatcatttg ataaaatcag
    99721 ttatcaacta aacagtcgtg atgtgccgtt tatcaaaaaa aaatctggaa aaataaagcg
    99781 tatggatttt gaagatgcaa aagctgcaat cagaagaatt tatgaacaga tgccggaaaa
    99841 ccaacgagct ggtctgaagc gcgaagactg gtggtatacg tataaattca agcaaaaagg
    99901 caattaccag tttgctttgc attttgatga taatgaggaa gcaacgggat atatcgttta
    99961 tcagcttgca acgtcttcct ttattattgc ggagtgggga tttttggatc atgatgcttt
   100021 ttgcagcctt gttcgcttcg taagttctca caatggtgct tttgaaacat ttgaatattc
   100081 atgcggctac ggcggtaatg atcaaaatta tctattagaa aatccatttg cttctgtaat
   100141 gatcacacct tatatgatgg cgaggatcgt agatatttct ttgtttttgg aaaattatcc
   100201 atttaaaaag agacaagctg catttgccct acaaatagaa gaagatcatt atgcgaaatg
   100261 gaatgaagga atcgtggaag taacaatcga aaatggaaaa aatcatctct caaaagtaga
   100321 acaaacaaaa ctcccaatcg ttcgaggaag tatccaacat atcacgcagc tattattagg
   100381 gtatcgtaaa gtggaagagt tggtattcca agaaagaata caggtgacaa aagaatatga
   100441 agaaacgtta agctcaatct tgccacagca acagccaatt cttaatgact atttttgata
   100501 aaaaacgggt gatgacaata tttttgtcac cacccttttg tttttcattt ggcatttgaa
   100561 ggaaaatgtt aaagtaaatc ctcttttttc gtaaatttga attttttgtt ttcttttgtt
   100621 ttagggtttt cttttttgtg gtcttggatt gcttctttcg taatcttttc ccgatttttt
   100681 ttagatgaat ctaagcgttc tgcgtatact ttttcttttg gcttatcatt cattggaaag
   100741 gacctcccta cattatttca ttctacctct agtttatcat ctgttaagga ctagtggaaa
   100801 cgttttgcct aacttataag ctgatttttt tagcagataa gcttgcaagt aaaaaacaaa
   100861 caagctacaa ttgatttatt gaaattgttc ctgtagctca gtaggataga gcaatcgcct
   100921 cctaagcgat aggtcgctgg ttcaattcca gtcaggaacg tataaataac ccctgtatcc
   100981 tttgcggtac aggggtttgt tttgtatttg tgccaaaaat gtgccaaact agttatcatt
   101041 tttatataaa ctatcgaaca cagtattgat tttttcttta tcctgatctt caagctctcg
   101101 aacaatatga agataagtag acattgtagt ttctaaactg ctatgtccta aacgtttcga
   101161 tacgctaagt atatttactc cttgataaag taaaatagat gcatgtgtat gccttagtcc
   101221 atgcaaagta aattgctttt caatccctaa ttcttttaat tttttgcgca aatatttgct
   101281 gacggcgttt gatgaaacta atccattttt taagttgaaa aaaacaaaat tatgagggtt
   101341 tttgatttca aaattctcga ataattcttt ttgattgatt ttaaactttt ttaagagatc
   101401 aatcgtatgt ttatcaatgg aaattttcct atttgaagtt tcgttttttg tttttcccca
   101461 ttcatttaat ttataattcc atgttttatt aatagtgatg atttgatctt cgaaatcgat
   101521 atcttcccat gttaatccta gaagttcagc aaatcgcatt ccagtggcac cagcaactaa
   101581 cacgagcata ggagaagagt actgcgcaga aaggttttct tctacgagtt tcattaaaga
   101641 tttaaattga tcataatcta aatatttatc ttcttttggc ttcaatgaat cttttccttt
   101701 gattactgct tttctagttg gatcaaacgg aattaatcct tcttctacgg catctttcaa
   101761 cgacgctcta atatggttat taaacttaat aacggtagat tttacatggt ctttagcata
   101821 cttatttaaa aagcgttgat atcccactct atctaaatca gaaatcaata ccgctggcat
   101881 atatttcttt atgttcatta acgtatcttc gtattttcta taagtgatag gagatactgt
   101941 tccttcttta taaagttgca tccaatcctc aaagtaatct gataataata gatttttgcg
   102001 atccccttta aggcctttgt tcaagttata ttctaattcg ttggcggcat cttttgcttc
   102061 tccttttgtc ttaaatcctg attttcttat cttcgtgtat tttccgtcat cttttttgta
   102121 tgaaatttcg tattgccaac tatttccacg tttgactaat cttgccataa ttgaatcagc
   102181 tctctttctc tgatacaata ggaactataa agaagcccat tgtttgggtt ttattatttt
   102241 ttgcacatcc tttttgcttg ccggcgcaag gatgtgctat ttgtcgtttt aatggtataa
   102301 ttggatgtgt attagatcat ccaatcagag gtgtttatta tgattaaagt gatttttaaa
   102361 agaataactg aacttccaga gtttagatta tttgttgatt attggtatgt ctggtttttt
   102421 attgttgcat tgctgatagg tctagatgtc atattagaaa gaaaacttaa gtaagagttg
   102481 agttaataaa ttgaattcct aaatgagata ttttgtagcc catattttgt ttgccgacat
   102541 cacctaatac tatggagcta atcgtttttt ctaacagacc aaaatcagat aatctattta
   102601 agctaccatc tattagctct tgtgaatagc cagacatgct gatatttcca gtgaaatttt
   102661 cgtttccacg actcattaag catgctaaca attgaatctc aatcgatgtt aattgattca
   102721 gtacaagaag ataatactcc tcgttatccc atgaagcgtt gttaattcga agtaaacaat
   102781 tcttataaag atttttatac atatctattt tattttgtgc ctttgatttt tctacctcgt
   102841 catttatccc ttcgaatatt ccaatgagtt ggtccttgtt ctctaagttg aaaacatctt
   102901 ctggaatttg atcgcgaatg ttttctaatg attcgtttaa atttttgtag aatttctcga
   102961 tgcgtttgaa acgcttctcg tttttagacc caaaataaag tgactgcaca acgccaccaa
   103021 tataaggaat tgctccaata ccgccttcaa ctattaattc aagatattct tttttggtta
   103081 gtttttcatt gctattatcc atagttacct cctattttgt catttccttt acaagcattg
   103141 tgactcctga tggcactctt ttgtataggt tttattattg tgcacaatct aactcttagt
   103201 ggggcgtggt tcatttattt tttacttact ttactattaa tcatatccca ttgagcatag
   103261 gatttttcta tgttcgatcc tcttgaacta atttctcctg taaaagttac tttatcgccc
   103321 tttgtaaagg tatcagcatt gtttaagtcc ttcgcaaaaa ttacatatga aactttaggt
   103381 gttgcagaaa tatcattcca acttttatca tcgtactctt tgtctgctat aatggctatt
   103441 ctagtagtca ttgattcgat aacagttcct tcaaaagtat atgttttacc actaatatat
   103501 ttagtaaaag ctgtattttg ctcagtagct ggagtaatag aataataact atctaagaaa
   103561 gcaccccagt catgattatt tgtctctaaa aattcttcaa attgagttag gcttttattg
   103621 ctgctgttag atgtagtagt ttgagtatca gatgatgagc tttcctgttt gttattgtca
   103681 tttgcctcgt ttgatgagga aagcgagaaa cctacggtag taaaaataat cccgataata
   103741 aggagaatca taggtgtttt cttatttgtt tttttgataa atcttacaat taacatgatt
   103801 aaacctataa taaataaaac aataccagta aaaccaaata taccgtccat taatagatcc
   103861 tctttctctt ttgatattga atattataaa ccaagcaatt cttttttctt aaaatcgaat
   103921 tcttcttgat taataatccc ttcatctaac aactctttat actttttaat ttcatctgca
   103981 cttgaaattt gtgtttcttt ggaattatta tctaatatag attgttgctt ctctatatat
   104041 ttttttaaat tttccatttc attccaatat ttttttgtaa acataacggt gttttcatct
   104101 ttcgtggccg ctaatatacc tccgcgactt tcgtttccgc ctagcaaggt aaattgtata
   104161 taaccattac tcatacctgg tttttttaat tgtacggctg atatattttt aaaggggata
   104221 gttttttctc ctttaatacc ttgattaact aaatttataa atccttttct aataattgaa
   104281 atagaatcat cagttacttt aatcaaggtt tttcctggag attttattaa aatctctttt
   104341 tccatttttt cttcctcatt tctgtgatat gatttttttt gtagaagctc atatatgagg
   104401 aaagagcccg tgttgcagca cgggcttttt taatgttttg ctgaaatcgg tttttttaat
   104461 aattcttgat gtattcatac atattgcctt gcgtaagaat attttttctt aaaatagcat
   104521 tggcagacag cataacaagt gtatctgagc ttattctgaa tagaataata ctccataaat
   104581 ttttcgagat taaactgaga ttcatcagtc agttcgttct caatatagat atttaataaa
   104641 attagaatag ctattttatc tgcttctgtt tcaaattttg agtgaaaagt tgtagaagta
   104701 tcgtacaaaa ctgaaaattc aaaatgagag gcgctgaaat gtgcaagttc atgagataaa
   104761 tgaaaggctt ctgcagtttc accgtataga ttttcattca aaaaaatgat tctgggtttt
   104821 ggatagtaga aaccaggctc tttcatctcc atataaacta ctttcaaatt gtattcgctc
   104881 aacatttctt tcaatttcaa atacatacaa accatcactc caactattca ttttcctcta
   104941 aagctttagc aattgcaatc gctttacgca ttgtctcctt agatatttct tttccatcaa
   105001 aagaaaaaac agtatcgtct tctgataaat ccacatgttt aggggtttct ctttcttctc
   105061 tacctagaag gtagtctaca gagacatcga aatagtcagc aatccgactt aattcatctg
   105121 aattaggagt attatttttc cactttgcta gataaccgtt agaatatcca aaattaattt
   105181 ctaactgccg tatagatatc tttttcctct tcgccaagtc ttttattatt tcataggtat
   105241 tcatcgataa aacaaccttt ctaaatgttt acaaaaaaag tttagaaaaa tacgcagaaa
   105301 taatttgact aattctgagt aatgagctat actatatctt gtaaacagat ttaacaacta
   105361 aaaagacaac aaaaaacact attgatatgt aaatgcagac cgccaagaaa gctttaaaat
   105421 caatgttttt atgtcttatt taattatgct cttagtatag agtattactc agatactgtc
   105481 aattgaattt agaaaaaagt tgttaaattt gtttacgaat ataaaagaaa ggaatgagaa
   105541 atatgaacac accgcaaatt tttaatttcg aacaaaacga agttcggaca attttagtaa
   105601 atgatgaacc atattttgta ggcaaagacg ttgcgagtgt tttgggttat tcaaacacta
   105661 aagatgcttt gtcgcggcat gtagatttgg aagataagat ggggtcgcga atcacgacct
   105721 caggtcaatc aagagagatg acaatcatca acgaatctgg tttgtacagt ttaatcttaa
   105781 aatcaaaact tccctctgcc aaaaaattta aacgttgggt aacaagtgaa gtgttgccag
   105841 caattagaaa acatggaggt tatctaactc cagaaaaagt agaagaagct ttgcttaatc
   105901 cagatacaat cattcaatta gcaactcaac taaaagaaga aagaactgga agattaatcg
   105961 cagaacaaaa gattgcagag tacgaaccta aaatctccta tttagatagc atattatctt
   106021 ctacagattc agtaacaatt agtcagattg cagcagatta tgggatgtct ccacaacaga
   106081 tgaataaatt acttcataaa ctaggtattc agaaaaaagt cggtaaccaa tggttattgt
   106141 gcaaaaaaca catgaaccaa ggatacacaa aatctcatac aactgagatc ccgaaagccg
   106201 atggtggcac taaaattgta atgaatacca aatggacaca gaaagggcgt ctatttatct
   106261 acgaattact aaaaaaagaa ggatattacc ctcaaatgga tttagaggaa attggttaga
   106321 aaggagtttt agtatgactg acattgcaga aatcactcaa cgagatagag aaaaaatcaa
   106381 agaatatgtc gaaagttcaa agttcttaac ttacaccatg cttgctgaaa gatttggaat
   106441 tagcaaaagc tacttatctt taattttaaa cggtaaaaag acttctgcag aagcaaacag
   106501 aattatagat tcgattatca ctatgtacga attgtaaagg gaggaacagc taatgcaata
   106561 tctagaagca aaaatcccaa ttccagaagg ctatgtaatt atctcccaag tggattatga
   106621 ggagttaaaa aaagctgatg atactggtag atggatgacg ttgccagaag tgctagaacg
   106681 gattaacaga aaatatgatt ggtttacttc tagagtttta aagaacccaa gatatagaaa
   106741 tattatcgat atcgagaaaa acaaaaatgg atttgtctat tatccagttg aaggaagaga
   106801 cacatatcta tttttaagaa gtaaaacact tgaattttta gaaacaaatt tttcggaaat
   106861 cttaaggagg caagcggatg ggaaaattta atagagcgct agtgttcagc gcaccgctaa
   106921 tcatctacgc tttagaactt tggggaagca ggcaagcgtt gataggaacg attgtttaca
   106981 tggtttggat ttttatgggg cttgatgaag ctgaagctga gtacagagcg aaaaagccaa
   107041 ccgagggggc tgactaaaaa tgaatagaaa agagaaacta gaatgtatat tactattact
   107101 cagtttaatt ctttcactaa tttctctatt gggaagtttg tatttttgat atcaacaatt
   107161 ttgtggattt gggttctatt tagagtaaat atcatttttg tttggtgatt aaggagttta
   107221 ttaaaattaa ttttccctac ttcaaatgca aggtaacaag atatagcact tttaggagga
   107281 atatttagcg gtacagcttc agagtatatt ctattatcat cgactgatcc tcctttagca
   107341 attaatttct taaatggagt agctgaccat ctgcggttta agttagcgga tgaaagttct
   107401 aaattaacta acatagctgg ttctgttgaa tagttagaaa tgattacttt tgtataaatc
   107461 atatctgcag cgaagtaaga agcattaagt tcaacttcta gttgagggcg cattcctttt
   107521 atttttatcc ctgttaaaaa cgtactcaat ataaaactta ttattgacat ccattgaaaa
   107581 attgttaagt gaaaaaaatt caaaataaac accaccagtt tttaactaaa ttataccaaa
   107641 aaggagagaa gaaataatgc aagaattagt aattttgaaa aataaagaag ctgtgactac
   107701 gagcttacaa gtggcagaaa gcttcgagaa aaaacatcaa catgttttaa gagatattga
   107761 tgcactaaaa aaagatgtgt ccaattttgg acagatgttt gtagaaggta atgaaccaga
   107821 ttcatatggc agaaatcgac gagttttctt cattagtaga gatggatttt tcttgctggc
   107881 tatggggttt acaggaaaga aagctatcta cttcaaacaa aaatacattg aagcattcaa
   107941 cgaaatggaa gatgttattc gcaagaatac tgttcctcaa acaattgaag atatgatgat
   108001 ctatcaatta gaagaaatga aagatgttaa aaaagatgtt tccatgctta aagatactat
   108061 gcgaattagc ggacaacaag agtttgaaat taagcaaaaa ggaaatatga aagttatggg
   108121 agttctaggg ggaaaagaaa gccgagctta tgaagaaatc agcaaaaaag tattctcaaa
   108181 attttggtct gaatttaaac gtaccttttc aatcccaaga tatggcgagt tacctcgtaa
   108241 gagattcgat gatgctgttt catttattga aatgtggttg ccagaaactg cgatccgtat
   108301 ggaaattgat caactgaaca gacaacagag actttttggt gatgacaatg aatagagctg
   108361 aagcgctaag aatagggacg gcaattgcta attgctggtg gaaatactat aaaccaatca
   108421 tcctaagcca acaacatatt gacaagcaaa aagcatggca acaaataaaa aagtgactcc
   108481 gccggcaagc aaagagtcac aaagaaaaca catcataagg agattttagc atatggaaaa
   108541 agaactttcc actctagatc aatatttgat tgatcctgat tggggcaagc cgaaaattga
   108601 ggaaacaagt ggtcgaaaaa tcagacgaaa tcttttgacg aatgaagaac tagcttggga
   108661 tcaagatgat ttaggcaacc atgtaactat ttgggatcat gtttatctta tccatctatc
   108721 gaagcattcg aataaacctg aatatattta cgtcatcgaa gatggcttga ttgatgcgct
   108781 agaagagtac gacagagata acttgattga tatctcttat tacggaccag gtaagaaata
   108841 cattgctgaa atggaggcag aatttgatga gtgaaatcaa agggacaacg aactttgaaa
   108901 aactttttag tcgtaagtta aataaaattc tcaagaaaaa aggaaatttt gattatttat
   108961 cttgggctca cgcgtgggag attatgaaaa agaatgatcc acaggcaacg gtaactatta
   109021 atgagtacaa acactacagg gttgtttctg gaactcatca agactttctt gttgaggaat
   109081 ataaaccttt tcttatggat gaaactggga cttatgtatc tgtctcagta acggttaaag
   109141 gacacacgga aaccgaatta tttcctgttt tagattatcg aaaccaacca gttgttaaac
   109201 caaatgcaat gcaaatcaat aactcattga agcgatgctt tgtgaaagca ttggctctac
   109261 acggactggg attatatgta tttcaagggg aagatattcc aacaccacct agaatcgata
   109321 caaagaaatt aaacatgcta gagacgattc tagaagcttt caatgagcag atgggtaaag
   109381 atatgaccaa aaccttaatc gaatatgtta atgagcagac agataaatta gggctcttag
   109441 ctgataacgt tgaaactatt gaacagttaa gctatgagca atgtgccttg atggagcgag
   109501 caatagcagc taagagaaaa gaattagata agaagtgata tgagtgttta aaccattaat
   109561 cgattcatat tcagcggttc tgaaaaagtt caaaggaaaa gacataagcg caaccatcaa
   109621 tgaggaagtg aacattgatc gactaaagac gatgtatgac ggctacgatg gtgatcgagt
   109681 cattgaaatt cgttttattg atcctagacg tttcaccgta cagcaacgaa acttcatcta
   109741 tgcgctgata ggcgatattt ttatcgatac aggcatgcca acggacttct ggaaggaatt
   109801 cttctacttt cgttttgaag gtgtcacagg gcgcaaaata agcctgaaag acgaatcgaa
   109861 tacaactgtg agtgatgcca atgtcttagc aaatatcatc ttagatttca tctttgaaca
   109921 tcatattcct ttcaaagaag gctatgagat tttacctgcg aatcaagaat attacttcta
   109981 caaatgcatc acaaaaagag tctgctgcat ctgtggcaaa acaggagctg acatcgatca
   110041 ctttgacaaa gcgctaggaa gacgaaagcg caaagaagtt gatcatgcag agtacacatt
   110101 tgcagcactc tgcagaatcc atcacacaga gaagcacaaa ataggtgtga ttaatttcaa
   110161 aaataaatat caaatcaaag ggatcaaatt aaaccagaaa acaatcaaaa agttaaatat
   110221 tggagggtaa aaatgacaga acatcgaagt tattatgcga ttataccagc caacgtaagg
   110281 tacgacaaaa gacttaaacc aaatactaag ttgttatacg gagagataac ggccttgtgt
   110341 aatgaaagag gcttttgttg ggcaggcaat gagtactttg cagatttata tggtgtgaat
   110401 aaagagacca tatcgcgatg ggtaagtgat ttgattaagt ttggatactt gaatcgggaa
   110461 atcatttaca aagagggtac caatcaaata atcaataggt acctacgaat taatcaatac
   110521 cctattgacg aaaaacgcaa tacccctatt gacgaaaaag tcaaagataa taatacatct
   110581 attaataata catttaataa tacaaaagaa tatataagag agttaccgcc ttcgaaaaaa
   110641 tcgaaggcta agcccgtccg tcataaatac ggagagtata aaaatgttct tttgtcagat
   110701 gagcagatgg agaaactcaa aacagaattc cctaatgatt accaagagcg aatcgaacga
   110761 ctgtcagagt attgtgaatc atctggtaag acttataaaa actatttggc aactattcga
   110821 agttgggcaa ggaaagaaaa aagtgaacct aagaacgcaa gcagtggata caagcgcaca
   110881 ggaagacgag agaagcttcc tgaatgggca atcgaccaag aagcctatct caagaaaaaa
   110941 gcgctagaac gagctaatag acaatcaaaa gcaccattct aagaggtgga aaaatgaaga
   111001 tcgattatct agaactaatt aatgaaatag cgaattataa aaagggcgag gaattagacg
   111061 tcctgagaga cgtatatgat caactcgaag aagctggaat tgaaggaatt aagaatgatc
   111121 gttcgagttg gagtaagctc agatactatt tcgcacttta tatcgataca acacaattaa
   111181 gaaatttagc atataccaaa ttactatttg ttgattgtgt taaaggcttg caaaaacatc
   111241 ttaatgaact tgagcaggtg taatcagatg gacctaaaga catttacagc acagattgaa
   111301 ctaatgcatc aagaagcttt aagacaaagt gtatcgtacg aagacaagtg gctcaacacg
   111361 ttccatggcg gacgtgagag cgcacttgat caagtactca aattactgaa aggagaatgt
   111421 cgggatggat aagaaagcgg caatgcagcg aattatcgaa ttgacttatt cagaagattg
   111481 gcaaaatgac aaagaagctg cttcagaagt gatgaggctt ggaagagcga tgtgggcaga
   111541 caagagcaac aagccaagac cacgaaaaat cgcaatttgg cacggtgaca aacttctagt
   111601 gatagggaca gctgaacagt tagcaagtct cacaggcttg cacgagaaaa tcgtgaggaa
   111661 aagagcaagg tgtggctaca cagacgctaa gaagagaacg tttagatacg tggaggaatc
   111721 atcatgacaa cagaagaagt gattcaaatg cgtattcgaa gccttcagcg tgagattgac
   111781 gatctggaac gaacaaaggc agtgatggtc aatgaaacgg cgagaaaggc aatcgatttg
   111841 cacatagaga atttaagaag ggaaatccat cgattggagg aatgagcgtg gataagaaag
   111901 cagcaatgaa aagaattgct gaattaacca agtcagaatc ttggcaagaa gacaaagaaa
   111961 tagttgcaga agtccaaaag ctcggtaaat caatgtggac tgaaaagccc aaacggagaa
   112021 cgccgagaaa aattgcaatc tggcatgatg accgaatttt agtaacaggt actgctgaac
   112081 agttatctga aattactgga ttaagcaaaa acattatctg ggatagagct aggagcttat
   112141 ggattgattc aaaaggacga cagtttaggt atgtggagga gagataatgg atctcattac
   112201 acaatacagt gacatcatcc tcaagaaaat catgatgaag attcagaaag ataaaaaatc
   112261 aaaagaacga gctgaattag ttaagttaga aatggctgaa acaggagcag gagtgcgaag
   112321 tagcaggcat tggaaagcag cagcaaacat tgaattttat tacaacgaaa ttcaaaaagg
   112381 gttcgatcag atgcgtgagc tggatcggca aacaaattgg agcaagaaac ttcatcaaga
   112441 tcgtttcaaa tttgtagaga agtataaaga aatattagaa gagtatttga ggaggacagc
   112501 aaatgataaa aaaactcgtt caattcagca tggatttata tgatatcgaa tcaggagcaa
   112561 cactatctgt ggaatcggac catctaatca taaattttgg tggaaagcgc cagattattt
   112621 tgtgggtagt tgatgatgta ctgtttccag aaattgttca tgatttcgaa gaatcaaaag
   112681 cggttgagtt tgaaatagtg aaaaaagtaa tggaattgat tgaaaaatac gaggaggaca
   112741 gcgaatgata ccgaagttta gagcgtggga taaacgaaag aacgtaatga gagatgtagc
   112801 cgtcttgcat tttactaaaa acggcaaaac aaactttatt gaatattgga taaatcctac
   112861 cgaattgaaa tcatatcacg tgcgaaacat cgacctcatg caatccacag gaatgaaaga
   112921 taagaatggt gtggatatat ttgaagggga tatagtatta gtcagcgtgc gaaatggctt
   112981 cgattactta gataataaag tctgtattgt caaaaattca atagattatt ccggattagt
   113041 ttgtgccact gttgatgaag acttagagta tcaaattttt aacacagagc tgtttgaaga
   113101 atacacgtac gaagtcaccg gaaatatata cgagaatagc gagttattgg aggaacagcg
   113161 atgaataaac aggaagcaat caaaaagtta gaaagtatta aagcgatagg aaatgatgca
   113221 atagctgctt gctataacga gagtataaat tcaggtatta cgttaatgaa aaaaatagac
   113281 gaaccgcaga aaccagttat tccacaactc gtggccggtt ggcttgagaa atctacggac
   113341 ccttttacaa aagctgaaaa aatagcgtat ttaatcaaat ctaaagatgg tgattcatat
   113401 tatttctgtg attggtttgt acgagatggc atagtgacgc aagagcaagg agaagaatta
   113461 ctcgcttggg caacaagaca atcatatgaa acactattga gcctatacaa cggctacgag
   113521 gttgagaaag agccgttatg ggcaataaag aatgccgatg gaaactatct tactaaatgt
   113581 gctttatggg gaaaagatgg agtaaattat agttttgaat gcaatccatc tcatcgattg
   113641 cttttcactg ataaagcaac agcggatgct gcagcattgt tggtgaatgg aacagtggaa
   113701 gaggtggtag aaagatgaaa ctaaaagacg gattttacgc tagcagtcac ggtatcggcg
   113761 gtttaatgct agatatgccg acaaagaacc ctaaaacacg caagaaatca aaattcaaag
   113821 tcggtgacat ggtccgctgt gaagcagaag agttcgttta tccgttcaga ggatacgtta
   113881 aaaagatact gtcaaactca gcaatcattc gtattgaaaa tacaatgaag tgtgatcgtt
   113941 cgactgcaaa acacaagcat tatttagctg tagcgagatt agttgacatg gaagtaatca
   114001 agagcaaata aaaaaagccg gatcgctccg actgattcaa taaatccaac acatttatta
   114061 tatcacataa aggagcggtt tgacttgatg caattgttac gagaggtaga tttcaaacag
   114121 acaagatgta atgcgagaga tgtgctgaag aactttcggc gtttggagcg gatggcaggt
   114181 cgctctttga tagatattaa gtcgccgatt ataacggata tgccgaaggc accgaagcat
   114241 ggcaataagg cagaagacgc gattattcag atgatggata tagaaacgga gagagatgcg
   114301 attctagcgg ctttgatggc tcttagtctg attagtcgtc agatactcta ctacagcttc
   114361 tgtgtgccag atagcttctc aaactacaga attagccgtg aagtgggtta ttcagaaaga
   114421 agtatacaac ggatgaagtc ggaagctcta atagagtttg cagaagcata taaacacgga
   114481 aaaataattg cttataaata atttggcggt tttttggcgg aatgatggcg gtttttagac
   114541 atttaccagt gttattatgg tagtgtcgaa agattaggaa acaggatcga caaaataaac
   114601 gaagggaggc aatctccctc atcgttttaa acttcttctt agatagacag caactaatta
   114661 tgaagaaaag gatgtgaatt caactcctcc taaattcttc atcggttgct gtttattttg
   114721 attagacagc agcactcaca aaactaaaca tgttcttgtc gtctttcaac tgctgctgtc
   114781 tattaattta tgtattggag ggaagaaaaa tgaaattatc agtagaaggc actccagaag
   114841 aaatacaaga attgctccaa gctattggta gtagcaagga gcaaaaggta agtgtttcta
   114901 attcagatat tgacggtatt tgcaattgtt taaacagaga aaaaatatct aatccttact
   114961 aagagaaaat atgttcgtta atgaatttcc aattttcctc tgtagctcta ccttgataat
   115021 ttttttgcag ttcacagatg aataaggaat cgttattatc aagtactgta tttaattttt
   115081 cacacatttg atttggattc aaattagttt taactaacca aaaagatttt tgtagcttta
   115141 tatatgcccc aaattctttt attatttcaa atactttatc atacttttgc cctgggttat
   115201 taagatcata actaatcatg tagggtttat acatgttgtc ttgcacatcc ttgttttata
   115261 tttcagcgga ccactcgctg ataaataaaa ttatacgctt agtatttatt ttcacaatat
   115321 taatttatcg taataacttt tgagtaaata gaacaaaaaa cctgcactag tttccgctag
   115381 tacaggcagt gactatatcg gttgataatc tagcatatat taaaaataat tgcaagaaaa
   115441 gaaatttata gtggtttata ccaaattatc aaagcaatgt tattttgttg ctgtctattg
   115501 ttttttaatt attcacacga taactaaagg tgggtgaaga gaaatgattc cattaataat
   115561 ttcaattttt gcgctctgtc ttaatgtcta tatgattgga tttaaaaatg ggcaaaataa
   115621 aaaatagtag cagccaagaa taattttata gtgtcactgt ggcggaaagg gtagacgcta
   115681 agcatgtgtg ctaggtcaat gcttcggcaa ccatgcaagg ttcgattcct tgccagcgac
   115741 attaaatgcc tatgacggtt acgactaccg aaaaaagatc gttaagaagc tatacggtgc
   115801 tacgtacggc aatgtagtaa gtgtgctatc tgtacaccac caagcttcgg tcactgtggc
   115861 ggaagtagaa gacgcagcgg taaatggcga gtagcctcgt gagagcctgg taagttctcg
   115921 tgagtggtgc aatcccactc cagcgacttt aagcaaccga ggcatcggcg gtttaaaaat
   115981 ataggggtgc gcaatttcgt acgcgttttg tgcatcgtgc aagttactat tacatattag
   116041 atcactcttt gagtggtctt tttatttttg cacaaaggag gaaacaacaa tgtatagacc
   116101 acaatactta gaacagaagt atgaagtaat cactgttcat aaaggtaatg gcgaaaaagt
   116161 atatgagtat agaagaccaa taaagagcga tacatataaa cgaaaggaaa acaatgaagt
   116221 tattccattg tatggcaaaa gaatagctaa gcattaaata agattgcgaa aggagacgga
   116281 acatgaccga ggaattctat agatggctat tacagttgac aagagaagat cgtttggtta
   116341 agttctatca gtctcctaaa tggcgcaggc ttagagagaa agcgatgaaa cgagatcact
   116401 atgaatgcca agagtgtaga agactaggta agtatcatag agtagagaac gttcatcata
   116461 taaaggaagt caaggataga cctgacttag ctttagattt agataatctt atttgtttat
   116521 gtgttgaaca tcataatgaa gttcatggca gatatcttac agcattagat aaacaagaga
   116581 agaagataga aagctttgct aacttcgatg caagtgaaag gtggtaagtg catgatcatc
   116641 aatgataatg gcagagagta tgatacagaa aagattgaag agtattcatc ttatactcag
   116701 ggattaatta aacgtttgat atacgttcgc tatgtaggta ttagggatct gttatcagat
   116761 aactgttgta gtaaatacaa agtgaatcaa gtaagagaag cgttgaataa agataataac
   116821 gtcgaaagaa taaaaaatgt ttttggatat agtattgaag agattaatta ttacattgac
   116881 ttcgctgaag ctttcattcc gatggtgaga taaccccccc ttaaaataaa tcgcaaattt
   116941 tttgggggtg atgaaacgga gggggctgtc aggaaaagag attttttcga actttatcat
   117001 gaaaggaggg ctaaaatgtt taaaaacgaa ttgtctcaaa atcgctacag agaaaaatta
   117061 cgccgctctt taataagcca attggaaagt cagaaaacaa atattgagcc attcttagat
   117121 aatgttgatc gttatatcag tttatgggaa acggcgatat cactggaaga agatatatcc
   117181 gagaacggca ttagactgga gaatggtaaa aagaatgaat cagtagcgtt gcttgtttct
   117241 gtcaacaaac aaatgggatt gatgttggat aaacttgcca ttactcctga attggtaggt
   117301 gaagcaaatg aatcaattcc tgagttataa gcatattgaa aattggttca aagctataga
   117361 agaaggcact atcaaggtat gcaaagagca attattgcta aaaaattatc tagaagaaag
   117421 agtctttact agagaagata tttacttcga taagcagatg gtagaggatt caatcaatat
   117481 accagcacaa tactttccat tcgaattaat tccgtgggaa aaatttctac aatgttttat
   117541 ttatggtgtt cgatggaaaa aagataaaac actagtgttc aatagatatc tttcattaat
   117601 gggacgtggt aatggtaaaa ctggttttgc ttcttggaac aacttctttc tactaaccgc
   117661 taaacacggt attaaaaatt atgatattga tatctatgcc aataatgaaa gccaagcaaa
   117721 gactagtttt gatgatgtat ttaaagtaat taaagatcat cctgatttag ataaaaaagt
   117781 atttaaagct acgaaggaag ttattcaaaa tatcgctaca aacagcaaac ttcgttataa
   117841 cacggcaaat gctagaacaa aagatgggaa gcgaccaggt gcaaaccgct ttgatgaaat
   117901 tcacgaaaat gaagattatt caatgataaa tgtggctact tctggtggtg gtaaaattcg
   117961 agattataga gaattttatg atacaactaa tggtcatgtt cgtggtggtc cgcttgatga
   118021 cattatagaa gaatcaaaaa tgattctttc tggagaactt ggaattgaca aggatggagc
   118081 agaattttct agtttgtttc catttatttg tcgcttggat aacgataatg aagttgatga
   118141 tcccgacatg tgggaaaaag cttgtccaac tattaattac aatgcagatt taaaacggaa
   118201 aatgtttcaa gaatactctc aaatgcaacg taatgctggt ttaagactta cgttcatgac
   118261 caaacgaatg aacagaccta tggaagatac acgatttgct gttgcttcat atgatgatgt
   118321 tctgcatacg aaagaaaaag aatttcctga aaaaatggat gaagtgatag gaacagtcga
   118381 ttttgctgat agacgagatt ttgccagcgt tgggttgcta ggaaaatacg ataaagatgt
   118441 ttattttaca caacatactt ttatccacga atcagccctt cgattacaaa acatcaaacg
   118501 agaggttata gatatttcta tagatcaagg aaaatcacag atcgttcatg gaaaaaatat
   118561 agaagctgat tatattgtag gttggtttct tgaaatgagt aataaatatt atattaaaaa
   118621 aatcgctatg gatatgtacc gtgcaaaaat attgaagccc gctttagaag aagcaggttt
   118681 tactgtggaa attgttcgaa gcggatctgt tacacatggt atgttaaaag atctggttga
   118741 tgaccttttt attaatcaac gtttattttt tggtgacgat gcgattatgc gttggtattg
   118801 catgaatgta tatgaagagc atatttctaa tggaaatata cgctatgaaa aaatagaacc
   118861 tgaaactaga aaaacggatg gctttttttc attccttcat ggtttgaatt ttttagatga
   118921 tatttatgat tctgctcctg taacagtcac aaatagctca gtagaaaata caggaactgg
   118981 atttactcct ctagtattct aacttgaaag gaggtgagaa agtggggatt tttcaaaagg
   119041 cggtaggata cttcacaaaa aaagcaacgg ttcctttaga agaatacttt tgtaaattgc
   119101 aagttgattt tgtgtatcga aaatttgcga ttgaaacttg tattgatttg attgcaaatg
   119161 cgatgagtaa agcggaattc aagtcatatg aagatggaaa aaataaaaag aatgatcttt
   119221 actataggct gaatgtagct cctaataaga aaaataatgc aacagaattt agaaaaaaac
   119281 tgatcaggag attaatattc tacaatgaag tattgatcgt ttctccgtct aataattcta
   119341 gcgaaatatt tattgcggat agttgggatg tcacagaata tgcattgaaa gatgatgtgt
   119401 tttctcaagt gcaaattaac aacatagtcc ttgatagaga atttctagaa agtgatgtta
   119461 tctatataaa atacgcagat caacaaatta ggcaactagt cgatgcgtat tatcaagcgt
   119521 atgggaaact catttctagt gccatgaatg tttacaagcg ctctaacgct cgtagatacg
   119581 tactgaaagg gaatttattc cgaccgcaag acaatacaac acaagatcaa atcaataaaa
   119641 tgatgacatc acaatttaag gcttttatgg aagctgataa tgcaggtgcg gtatttcaat
   119701 tacaaaatga gtacacatta gaagatttca gcggaaactt ccaaagcaat tcaagagata
   119761 taaaaaactt aatagacgac atctttgaga tgacagcagc agcgtttcac gttccgaaaa
   119821 acctactaaa gggagacatg agtgggttat cggatcaagt ggacgctttt ttaatgttcg
   119881 aaatcatacc gattgctgaa cttattcagg atgcgtttaa cgctagtctc tatgaagtag
   119941 aagaatactt gtcagggaat tttgtacgtg tggatacaac tatgatcaag attactagct
   120001 tcaaagattt ggttgacgct attgatgtag gcattagaaa tggagtattt acaatcaacg
   120061 aaggaagaga acgcgttgga aatgatcgct ctgataaggc gatggcagat gaaatattta
   120121 taactaaaaa caatcaacaa gtatcgaaag gaggtgaggc gaatgacgac aatgaaaaca
   120181 tttctagcag taaagaatga aggcgcagta ccgcaaattt ttattcaggg atttattggt
   120241 tctagttggt tctttgaagg gaatactgac aagggaatca aaaatatttt ggatagtcta
   120301 ggtgatcaag aagaaattga agtagtaatt aattcaaacg gtggagacgt atttcaaggg
   120361 attgctattg ggaacttact taagtcaaat aaagcaaaag ttaacgttgt gattaacggc
   120421 ttagccgcta gtgctgcttc aattatcgca atggctggcg atactataaa aatctacaac
   120481 aatgcacaat tgatgattca ccgcgcttcc acatacggag aaggaaatgt cgatgacttc
   120541 cgtacgattg ctgaccaact ggaatcaatt gataaatcgg taaaggcttc atataaaaca
   120601 cgattcaatg gcacagatga agcattgcaa gaacttcttg aaaaagaatc gtttatggat
   120661 gcagaaacag ctttgagtta tggattggtc gatgaaatta tcgatgcaga aaatagctca
   120721 ggtactgaag ctaaaaaaga acaaagcgtt gaagaaattt tgaatgacgt taaagaaaaa
   120781 agagcagaaa aaattgctgc atttacagca gcattaaata aaacatttgg acaaggagat
   120841 gtaaaataat gacagttaaa aatttaaaag gtgtaacagc tgcaagcgac caattgatga
   120901 aagcttttaa agatggtaac gaagaatctt ttagcgcagc tatggtaagc ttatctaagg
   120961 aaattcagga taaaatttta gaagaagcaa cagcaaaaaa tcaagatcaa ttagtattaa
   121021 tgaaccgtgg tcagcgtgta ttaactacac aagaaacaaa attctataac gaagtagtga
   121081 aaaacgaagg ttttgcaggg gtcgaagaat tagtgccagc tactgtattt gaacgtgtat
   121141 ttgaagattt agaacaatct catccactat tgcaaaaaat tacttttgtt aacacaactg
   121201 gtgtaacaga atggattgtg tcacgtggag tcaatccagc atggtggggt aaactttgcg
   121261 aagctgttaa aaaagtttta gataatggct ttgatgtaat taacatgaag cagttcaagc
   121321 tatcaggtta tattcctgta tgtaaggcaa tgcttgattt aggtccagta tggttagatc
   121381 gttatgtccg tactgtttta gtagaatcat tgagaattgc attagaacaa gcaattgttg
   121441 atggtactgg taaagatatg ccagtcggaa tgatgcgtga catgagcaaa caaactagcg
   121501 gagaatatgc tgaaaaaaaa gcagaaccta ttacagcttt agatgctgta actatgggcg
   121561 gtttgatggc gcgactatca aaattcaata tcgaaggtgt gaatgatccg atttatcgta
   121621 atgtgaatcc ttctgatgtg gtcctaattg tgaatccaac tgattactgg tctaaagtat
   121681 tcccagctaa gactgtacta actgctaatg gagaatacgt acaagtattg ccagtaccag
   121741 tttcagattt gcagtcaacg gctgtgccag aaggaaaagc agttattggg gtagcctcag
   121801 attacttcat gggtgtagga tctacactaa aaattgaagc ttcagatgaa taccattttg
   121861 ttgaagacga acgcatttat ctagctaaac aatatgcaaa cggtcaacct aaacgtaacg
   121921 atagtttcat tgtattagat attagcgctt tgggaactac tactacaact acaaaaccaa
   121981 caaccacaac aactacaaca caagcgtagg tgatcagaat gaagtatatt ctttgtcagc
   122041 cggcaatcaa tcggtttaaa tgggagcttg aagtttgttt aactaatctg aagaaactag
   122101 gaatcaaaga tatcgtattg cttttcagca gacacgatga tcagattcct attttttttg
   122161 agaaggaata tggtgttgaa gttcatgtgt acgatgatct gcgggacgac aaagagtata
   122221 ttccttcgat taaaccatat ttatggtgga aatatttaga agaagatcat tcgcgtgagg
   122281 acgaccgata tttctatatc gattcggatg tcattttcaa taaaagaatt aatttgcgca
   122341 aattgccttc taaagatgat gtttggtatt gtagcgactg ctgtagttat ctaagtcttg
   122401 attatattag aagctgtgaa aacggagaaa atattctaaa agatatggca aacattgtaa
   122461 atgttacagt agaatctttg gaaactataa acactaattc aggaggcgca cagtgggtta
   122521 ttaaccgtcc taaagcgaat tattggaaaa aggtttatct ggattctaat cggctatatc
   122581 gctaccttag agggcaaaaa acaaatatac aaatctggac agccgagatg tgggcacagc
   122641 tttggaacat gatgtatttc aatattggtc ctaaagttca cgaggaatta gacttttgtt
   122701 ttgctactga tccaatagaa aaagttaaag aagtaaaaat cttacacaat gctggagtaa
   122761 caacaaacga tgaagattta tttttcaaag ggagatacgt gacttctacg ccttttgatg
   122821 aagatttatc atttgtaaac aagaaaaaat gctcttacgc atatgttaaa gcaattaagg
   122881 cggtggttag atgacgcctg aacaagtgac tgaagaattg ctaatagctg tgaaggataa
   122941 tatttacgtt acctggaacg aagaagatga gtcaattaaa aagatgatag ctaaaaatgc
   123001 tgtttatctt caaagtaaag tgagtacaac actttctttt tctcctgaaa gcttagaata
   123061 cggattgcta atcgaaagat gtagatacga ctggaatcgt gctttagatg agtttgaaca
   123121 aaatttcgct agtgagttat taggtttcat tcaacattat gcgctacaag aatatattgc
   123181 aggtgatgtg aatggcgaat aatcgtagac tcgaagaaac attcaacgat ggttggttaa
   123241 agattttgac gcaaactacc aaaagaaatg aactaggaaa aaagattggt gtagaagata
   123301 cagaaatcac ttctttaaaa tttagaaatc tttccatgag agatagtgat ataacagcta
   123361 tggatgcgat gggatcgaaa ttaactaaga aagtaaagac tccatttcat ccaatcgcca
   123421 agaaatttaa taaagatcaa tattttatcg taatcgatag tatgcgttac aacgttatct
   123481 atgccgatta cgataatttt tatatctatt tttatcttga aagtgtgggt gaatatggtg
   123541 attgataatt ctaaagaaaa agaacgttta aataagcaaa tttctgctat caaaacttcc
   123601 ttagaagagc attttggcct caaactcttt caagactccg taggcgagga tgagctacct
   123661 gatgatttta attacttcat tctcgaaaca ggagaaatag aaatgatcac tgagccaaaa
   123721 tatagcgtgg gtcaaaatct atatctaact ttctattcag aaaatagaga agatttaaca
   123781 ggagactcac tagatattat ttcattgatt caaaatcgtt cgattcgttt tcagagaatg
   123841 gatcccaatc atttaaaact agagaaccaa gatcgctata tcgatcaatt ggtatttacg
   123901 tttagacgat tattgaagag tgattgtcat ggctaaaaat agttgggagc taaaaataaa
   123961 tggacatgat gaacttcttg tgcggatgga acgctattca agcgagagcg aacgactgat
   124021 taacgaagca ttgaaatcaa aaggttcggc tattgcagtg gataggatta cagaaaaaat
   124081 tcctgtttct gaagcagatt taagaagagg gcaccaacac gcaaaaaata gtcgtccact
   124141 taagactcaa tacattaatt tgggtttcat cattagacct acaagaaaat ttgagtattt
   124201 aaaatatcct gatttgggga taggtacttc taaaagaaat cagccggacg aatttatgag
   124261 aagaggatta ggtcttgcac ttgatccaat tacagaactt ctgattcgtc aattcgataa
   124321 attaaataaa tagggggaac aacaatggct aaaacaaaaa ctgtagtaac aacgttcgat
   124381 aacgtaagta tcaaacgaat tgcttttaat tttaagaacg caggaaatgc aatcgcaacg
   124441 aattgtaatg gacaattaga tggcgaaaca gaaatgcaaa cggtggttaa aaaatgtgga
   124501 gcgacagaag taaaatcaaa atctaaacca atcaatatga cggtaacaat tactgcacat
   124561 gtaccgatgg aagtttatcg acgtttcaat gggttgaaac aagatggacg tattaaacca
   124621 ggcatttact cttacggtcc tgattccgta ggcgaagatt tctcacttgc tgcagagatc
   124681 gtggatgact tcgaagaaaa tagaaagtta gttggtatgt tagcatgcac ttcgaataca
   124741 ggattaacat tctctattga aaatggtgcg gatgaagtag ctgcgttaga actagaaaca
   124801 aaagttatgc aagatgaatt tggtaaattt tatcatgaag caattgttgc agaacttgaa
   124861 gaagacttaa cagatcaatg gatgacgaat ctatctgctg atgtgattaa aaaaacttca
   124921 gttgtgacaa ctacggccac tcaatcacag taaaaaaaac ggaggtagcg aaatgaacga
   124981 agattactca aaaattgaac taaacgatgg aacaattttg aatttagaac ctaaactgaa
   125041 tatcaagaaa ttattgatga tcaatagaga ttttaacaca gacgagtttg caaaaatgac
   125101 tgtgggaaaa ggatccatgg atatttctgt tattcaaggt gcaaaggctg tgtatattgc
   125161 ttaccgccaa gcgaacatga ctgattatat ttcattcgat gaatttatcg ataaatggga
   125221 ttttgatatg gctactgcca gctatattta tcaattgatg atgttcaaac aagcacgcga
   125281 tgcttatcaa aaagaatttg aaaaagcaaa taaggaaaaa aagcttcaaa agtaaaaatt
   125341 ccaaagctct tagttgaaac gtgggtcgat gtctattcga tgttgaccga cgttttttct
   125401 atgccttcag atttggtttt aagcgatatc tgtttagatg acattttgca aatggcttac
   125461 aacaagagtg cttatgaagg atggaaaaac tatgcaataa accaatccca gaaaaactaa
   125521 agaaaggagg taaaaaatgg ctaaaaagag aacagaagca gaagtaactt tcatagctaa
   125581 cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct gaattaacta aaaatagagc
   125641 agaattaaaa ctagaacaag ctcaattaca acagactggt tctgaatcag acaagttagg
   125701 aagtaaatta tcttctttag aaaagcagta tgaattacaa agtcaaaaag ttgaagtaac
   125761 tagccaacgt ttagccaatg cgaaaaaata ttatggagaa aattccaccg aagttcagaa
   125821 acttgaaaga gaactgatta atcaacaaac agcgcaacaa cgtttgtcaa acgaaattga
   125881 taaaacgagt aatgcactag ctcaagcaaa aggcgaaata cagacgtacg agtctacaat
   125941 gcaacagttg gatagcgaac aaaaaaatgt tcaagctagt gcttctctga ttgaatccga
   126001 atacaaaaaa tggcaagcaa ctgctggtca atcagcttct gaagccgaga aattagcgaa
   126061 agcccaagaa tatgtttctc aacaatctga aaatgcggag aaaacgatag atatcctaag
   126121 acgacagtta gaagctacac agtctgaatt tggcgctaca tccacagaag caatgcagat
   126181 ggaagcgaag cttaatgatg ctgaacgtga atttgaagag ttaggacaag ctgctaaaaa
   126241 tgtagataca actaacttgg acgatatcgg aagcaaaata gatatgaata atttaatgga
   126301 agcttctgac gttttaagcg acattggcga taagcttaca gaattaggga aacaagcagt
   126361 ggactctgct aacagtgtag gtagttccca gagtaagata caagctaatt ttggtttgtc
   126421 taaacaagag gctgaagaat taacgaatgt agccagagac atttattata aaggttttgg
   126481 agaatcgtta gatcagtcca cagatgcatt gattttggta aagcgtaatt taggagattt
   126541 aaataatcaa gatttacaaa atatcacgga acaagctatg gtcctagaaa acaccatggg
   126601 cgctgatatg gatgaaacgt tacgtggtgt aaatggctta atggtcaatt tcggcttgag
   126661 tgctcaagat gcaatggatt taatggtttc gggtactcaa aacggtttag ataaaacgca
   126721 cgaattaggc gacaatatgg cagaatatag ccaattatgg agtcaaatgg gatattcagc
   126781 tgatgaaacg ttcggaatgc ttcaaaatgg tttagatgcg ggtgcttata accttgataa
   126841 agtcaatgac ttagttaagg aaatgggaat atcgttaaca gatggtcgat ttgagcaaaa
   126901 catggatatg tttagtgaaa gtactagaaa agcttttgaa gagtggaaaa atggcggagg
   126961 aacacaaaaa gacgttatta attccatgat tcaagatttt agcaatatgg atggtcaata
   127021 cgaccaatta aataaagctt cgacaatttg gtctgcgctt ggcgaagata atgcgatgaa
   127081 agttgtccaa tctttaactg atgttaacca tacatttgat gatgttagtg gatctgcaca
   127141 aaaaatgaat gaagattcta ctactccgtt gcaagagttg aacgggaaaa tagctgaatt
   127201 aaaggattca ttagctccta taggcaacac aatcatagat gcactcgaac cagtaattga
   127261 ttttctagga aagatggctg atgcgtttaa taatcttcca caaccagtac aggatttcat
   127321 tgttgctata ggtggtctta cagcagcatt tggcatactg ttaccggcaa tactagccgt
   127381 gtcatattta tttggtccga tgatgcttat aattggagga attatagctg ttatagcagg
   127441 cgttattgtg gcaattaaga actggggtgc aattactgac tggtttagtg gtttatggaa
   127501 aaaatttact gattggttgg gtgatacttg ggaaagtata aaagacggag cctcatcagt
   127561 ttgggatggg gttaaagaaa cctggtctgg atttgtagat tgggttcaag atatttggca
   127621 aggagtttct gattggtttg gagagctatg gagcggatta gttgaaggag cttccaacat
   127681 ctggcaagga gtccaagaaa cttggcaaac attcgttgat tgggtttcaa atatttggaa
   127741 cggagtcaaa gaagtatggt cgattatttg ggcagacatt gtaggaattg ttcaaatacc
   127801 atggacatta ataacgtcat tgattcaagc tggtattaat attatcgtgg gtatttttga
   127861 tgtagctgga cagttattgg gcgcagcttg gcaagctgtt tggacaccta tttctgattt
   127921 ccttaaaaat acttgggata ctatgacaca atggataagt atcgcttgga atgggattgt
   127981 aactacattc catactatat ttgatccagt agtggcatgg tggaatggta tatggacagc
   128041 tattagtact acggcttcaa atatttggaa ttcaattagt gcaacagctt ctagtatttg
   128101 gaacagtatc aagaatacaa tcactagctt ggtacaagca gctgctacag taattcaaaa
   128161 tatttggtca actgtatcta gttggttagg tggaatttgg aattcaatca gctctacagc
   128221 atcaaatatc tggaatagtg tgactagtag tataagcaat gctataaacg cagctaaaag
   128281 tgccattcaa agtgtttgga atagtatatc ttcgtggatt agcggaattt ggaacggtat
   128341 caaaaatact gctttgaatc tttggaatgg aattacaagc actattagct ctaaagtaaa
   128401 cgatggaaaa aatgcaattt caagcggttg gtccaatcta acaggtattg tttccgacat
   128461 attcaataat gttaaaagta caattgctaa catatgggaa ggcatcaaaa agactgttag
   128521 cgctccaatt gattggatta gagacaaaat cagtggcatt tttgataatt tgaatatttc
   128581 tataccacat attccgttac cggaatttat catggaaggc agctttaacc cgctaaaagg
   128641 tcaaatcccc catttgcgtg taaaatggca tgctaaagga ggtatcttta ctaaaccaac
   128701 tttactaggt ggaatgaacg gtgtcggtga agcaggacct gaagcagttt tacctttgaa
   128761 aagatctgtt ttgcaagaaa ttggtgatcg tatcttgagt agcacatcag tttcatctag
   128821 ggcacaaacg attcaacctg tgaataacta cgaattcaat ttcacaattg atggtaacgc
   128881 agatgaggtt actatgaagc aaacaactca acaaatcatt gatagcatta caaaaattca
   128941 aaatgataat gcttcggcat ggcgttaaac aggagagtat ttctcctgtt tttttagtat
   129001 taaaaaggat gtgaaaaaat gactgattgt atacattcta taatcgatgg atttcctgat
   129061 tatttgcata aattggcttt agctgaaaga ccaaccatac cttctccaaa aagacagaga
   129121 gttgaaactt ctgttttagg taggttaggt ggcttagtac aagattactc gtttgaagat
   129181 atgtcgttta cattgcacta taactattta gaggatgtgg aagaccatca agcgttcaag
   129241 caatcgtttt atatcatgcg tcattggtta aactatgcaa agaaattaga attctctgac
   129301 gatcccaacg tctattacgt tatccagact atcgatattg gggatgcaga aaacgatatt
   129361 gttgaatggg gagagttcga tgtaaatatt actgcgaaac cattcgcaag agttcaagaa
   129421 gatgtaccta taaccgtaga taaaccacag tcatttaact tgctgaataa tagtttagaa
   129481 gaaagttttc caaagattat catcactcct tcagctactt catgccagtt catcttaaat
   129541 gattatgtgt ttagtttcga aggcttagta gcaggaactg atgtagtcat tgatagtgat
   129601 ttgatgcttt gctacgaaga gcaatcggac ggagatattt tagatcggtc caacaaaatg
   129661 aagaccatgc aatatccgac attgcaagtg gatatcaatc attttaattg cactggtttg
   129721 agcaaaatac aaatttatcg taacgggtta aggtaggtga aatagatgat cgataattta
   129781 ataactattt acgataaaaa tgacgcgaat aatttagctg aacatttata tgatacgcaa
   129841 ggtttaggcg ctttgtcaga ctggttaaca gctactgtta gcaataaact aaacggagcc
   129901 gagatatttc agggtactta ttcaataaac ggaactaatg cagatttgat tgtagacgga
   129961 cgtattattc agtgttatgt agatgaaaat cgagcaaaac agcgtctacg gatttattat
   130021 gcaaaaactt ctgtaatagg caatacgata gaagtaaaag ctgaacctat tttcaatgat
   130081 ataagaaaat cggtgttgaa taaatatgac agcggaacag aaaagatcac tgctactcag
   130141 gcatggcaaa acgcaaaagt tttagcgaaa ccagctatcc cttcgcagtt ttctttctcg
   130201 tcattagtag atacgcttgc taatgtgaag atagaaaagg cgaatttttt agaattcttt
   130261 ggtggaaaag agggatctat tctagatcga tttcatggtg agtttctaaa agataataac
   130321 acattacgtc atgaaaaaag tctaggtacg gatcataaaa tcaaagcgat ttatactaaa
   130381 aacttaactg gtcttgactt agagattgat gctcaaagtg ttttagttgg agtttatcca
   130441 ttcattagca gctcttcaga aggagaagac gagatcactc taccagaaga agttattttc
   130501 acggattacg tggatgatta tcctgctgga tatgtttctt ttgttgattt taaagacaaa
   130561 gcgactgatg tagccacatt aagggaagct gctaaagact ggttgaaaac aaacatagat
   130621 aaacaaaaac cacaagtgag tggttcgatt gaattagtac cattgaggca tcaaagaggc
   130681 tatgaaaaat ttgttgatct agaaaaagtt tcgatgggtg acggagtaga tgtgtatcat
   130741 ccacagttaa aagtgaatat gtcagcgaga attgtggaat atacgtttaa tgttctaacc
   130801 aattcatacg ataaattagt tgtaggaaac gtcaaaacaa acttcttaga aaacacagag
   130861 aataatgtca gcaatttgat taatgatgcc attgatcaat tgaaaaacgg tggcgaaatc
   130921 agtgatttac tcaatgatat tgtagatcat caaactgata tgattactgg tcaaaatggt
   130981 ggttatgttt tattagatcc taaagaagcg cctagtcgta ttttgattat ggacacacca
   131041 gataagaata ccgcaaggaa tgttttacaa atcaacaatg ctggtattgg tttttctaaa
   131101 actggcatta atggaacata tgaaacggca tggacgttag atggcggatt caatgcctcg
   131161 tttattacgg ctggtgaaat agtaggaatt actattagag gtactacatt aattagtgat
   131221 ggtgctgatt atagaacaag tattgctaat ggcaaaatga cttggtactc aaaaaaagtt
   131281 aacaaagata ttatggagct agaagcacgt gattatgtaa gtgctgatgc cggtattgta
   131341 tcatacacca tgaaaactgg tggtggtttc atgattagaa atccacaggg taacttggtt
   131401 tttagtacgt gggataatgg taataacaga ccgtttctat cttttggtgc gcccaatttc
   131461 aggtatagca atgctagtta tgtaacttct ggcgacggta gttctttaag cattaatggt
   131521 agtgcgggta actcatggga atttaaggta gctggtagga ctatgaaatt tactagtgat
   131581 ggtatgctaa cgttaccagg ttgttttttt ggttcatggg aagatgggaa acttgctagg
   131641 tttgaacaat caacggtaca agtatataaa gattttactg ttagaggtac taaaaactca
   131701 actgtaccaa cagaacatta tggacaacga ctattgaacg cttatgaaac tccagaatat
   131761 tatttcgctg attatgggga agccgttaca ggtgacaatg gtaaagttcg tgttgatatt
   131821 gaccccatgt ttgctgaaac agtaaatcta agtcggtata tgacacatgt gacacctaca
   131881 gaactagttt tgtgtgctgt tactcatgaa gatattgacc atttcatcat tgaaactagt
   131941 aagccaaacg tattagttag atggaattta gtggcacacc gtctagggta tgaagatatt
   132001 agattaaaag aggatacagc atatgatagc acagtgcttg accaaaaacg tttttaaaac
   132061 gaagacaagg aggtatataa atggctagca gtttatataa tttggcttta gatttcagca
   132121 aagaattaaa ctacaccaaa gctattatgg ctcgtcaagg tgataaaggg attacggtga
   132181 cggttaaacc gtttctaaat ggcttgcaga tggatacgag tggcggaaca tttactttaa
   132241 aaggaacaac accatctaac cgttacgtag ataatgttgc aactagtgta actagtgaag
   132301 aagtcacgtt ttctcttgat ggcacattta tgagtgaagc aggatattat aaacactgct
   132361 acgtagaata tagaaaagac aatcaaattt taacaacgca agatatcatt tttttctcac
   132421 taggagtgtc tgacatttcg caaggccaag ccgatgaata tgtttcgcaa ttagaagagt
   132481 tgattcgaaa gtacaacgaa acttttgatg cttttatggc tgaaatcaaa ggtagagtgg
   132541 atagcttaaa tcaacagatt actgatttaa ctggtcaagc taaaacgcta caagacaagt
   132601 tagatgctct gaaagaagaa atttctaagt taggtaactt acaagtgatg tacagtaaca
   132661 gcatcgactt cggggactat gattattcgg agaacccgaa tttaatgcca tatattacag
   132721 aaccttgggt tggacctttg ttaggtaatg gacatacagt taaagatagt gttaaaaggg
   132781 ttataactca tactaaaact agaacagcta attccggcga catattatcg cttggcttag
   132841 gtattccgtg tacagcggaa gctaataata ggtatcttat aaccacttta cgaccatcta
   132901 cgacatacac attaagcgtt actatgagtg tcggttcaga ttggactgga gagaccaata
   132961 ctataggggt taggcttaga tatttaaatg aacaaggtgg tatagaactg cccattaatg
   133021 cattaatacc agcaaatgta gaacgcgata aaatggtcac tcatacattt actggtataa
   133081 caaaagataa tgtaactagc ataacaaact gttatgttga aatattctca cttaatagtg
   133141 aatataaagg aacggttagt gtcagctatg acgttaagtt aaaagcacac taccctaact
   133201 tactagatgg cccttactgg ttaggtaaag ttcctttagg cgagaatatt gctgacccta
   133261 cagttgtctt tccacacaaa actagtgaat atatggttta tggtagacgc aatacagaaa
   133321 actatatcgc tgaccaaaca tataccatat caatgaaagc aactaaacta acagttcaat
   133381 cgtttgccgt gtatattgct gctggccgcg ttaaagtagg agacatgaag cctactgagg
   133441 ggttagctaa tacatgggag ttaactttta ctgtaactaa gcaacatata gatagtgggg
   133501 taactaatta tctggaaata taccaatacc cgtcagctac aaaaggagct gttcaaattg
   133561 agtggctcaa actagaaaaa ggcaatactc gaaccccgaa tattagtgag tataaatatc
   133621 gtggtactgg tatgcgtgat tcaaacaatc caaaagatta tgtttgggat ctagcaccag
   133681 aatatgtcga agataatttg gccacagata ttaaaatttc tgaaattact ggtaaagcaa
   133741 acaattatac cgatgggaaa gtatcggaga ttaattcgca gttgactgct tcaattaatg
   133801 aagtagacac cacagctaag gatgctcaaa caaaagcgaa tgctaatgcg actgctatag
   133861 atgaattaga caataagatc gatgaacgca ttaatgatac agctactacc acattaacag
   133921 ttacaaacgg gaataccgga tcagcaaagc tttatcgtga aggaaaaaca gtttctatat
   133981 attttgtggc tttaaacgga aaaagcagtg gtggaaatga ttcaacgata ctaacaattc
   134041 cagaaggcta tcggccacca attagttttg agcaactggt tggctcgata gaccgttcta
   134101 ctttgaacag tgctcagtta tctattggtg cagatggagc cattaaatgg cgaagaaact
   134161 caagttatgg atcggattat acctttgcaa ttacttacac gatttagaaa agcgtgaatc
   134221 gatatgaagg cagcatatag accaattgaa ccttacggat tcgagcaaat cattgtgaat
   134281 gatgaagaac atttaccgga agaatgcaca gaagtcgaac caccgattcc aaattggaaa
   134341 ccgaaattca attactggga gggaaataaa tgaaaaacat ttggaaatat ggacgtactg
   134401 gcggagagta cgcaggaaaa gtattggacg acatgcttgt atccgttcct tacacagatc
   134461 agccaccgct tgaaggaatt cgtgctgatg gcgaaccgtt aacaatcgct gatcaaatgt
   134521 ttgatcctaa attgaatcaa tggattattt tagcgaacgc actagatcac aacgatttaa
   134581 acaatctcaa agcaatgtat gagtcgttag aaaatgagaa cggcgattta aaacagatca
   134641 atgccaaact catgctaagc gatgtagcaa ttaaacagga aaatactgca ttgaaagaaa
   134701 aagcggatag tttagcacaa atcaattcaa aaatgatgct tgcttcgtta caaaatagca
   134761 aagacatttc agaaattaaa gagcaactaa atccagcttc aaagggaggt gagtagtatg
   134821 tttagtttta gcgatgtgaa aatgatgtat gattggggct gtttcactaa cgaacaagta
   134881 atggttttcg ttccgttgtg cattactgaa gaaaaagcag ataaaatcat tagcaaagaa
   134941 gagagcgcat cttaattgat gtgcttttta ttttgattca aggagttgtc acatgattaa
   135001 tttaggggaa tggggagcga tagcaggatc aataaccgct atcgtttctt tgattttatt
   135061 agtaataaaa ccaattactg catctttctc gaagattact gagactcttt caaaagtaag
   135121 tcacaattta gatttgctga ctaaagattt agaatcgagc aaatcagatc gattgatgat
   135181 tcatgaagaa ctaaagaaac acgatgaaag attagataca catgcagaaa aattggtaga
   135241 acacacgcaa caaattaaaa ctttatttag ggagagaaga aaatgaataa taaaacgttc
   135301 gaagtactaa aatggttcgc actggtaatt attcccgcac tagctacttt cgtggggtta
   135361 gttggtaaag cgctcaattg gcagtacaca gatatctgtg ttgtcatcat tactggtttt
   135421 ggcgcgtttt tagggagtgt gttgggtgta tcaaatcgaa cctacaaaat gttctcggct
   135481 gaaagcgaag aaggaggaaa caaatgaaaa agaaaattac tattactgcg atgagcctgt
   135541 taacggctct ttttttatta cccattaata cgtttgctta tactattaat gacgagtata
   135601 atttagcgcc gaatcaagga gactccagat tagcaattcc taacaaaatt attttgcacg
   135661 aaactggaat agatgcacca gcaagaaacg tagccgccaa catgaaaaat aattataacg
   135721 gaagcaattc ttatactaca gatgttattg gtgacggtgg gattgtttac cgtgtgggtg
   135781 agcaaggata tgtttcgtgg ggagctggta acgctaatcc ttatgcgcct gtacagattg
   135841 aattacagcg cacatatgat aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat
   135901 atacaagaga tagtgcaaaa aaatatggaa ttccattgac tcttgatcaa ggaacttctt
   135961 tatttacaaa aggaatcatt tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca
   136021 cagatccata tggttactta tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt
   136081 tagctcatgg atttaccgat gaaaatccaa caacttctga aaacaagcct gtcattgatc
   136141 caacacgagc tggtgcagct aatcctacgc tgacagatgg aacaaatcac gcccacattg
   136201 atcagtttgg ggaaatcgaa aacgcaaact tgcatgtggc tggatggcac attgctaact
   136261 ataaatacga gtatattttc attatggact acaatactgg gaaagaatta gctcgagtaa
   136321 gagctgatgg aatttataga ccagatgtaa accaagctta taatacttct ggaaatgttg
   136381 gttatcatgt atctttcaat atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc
   136441 gggcaacgaa tgatccagag ggaaacacta aaggcggtgc gcaagatttc catgacaaac
   136501 gttggtattt aaatattcct aaacgataaa aatagctcct cgttgaggag cagtacataa
   136561 ctatattgac aactataaaa attattcgat aaaatagtga tgttatcgca tatcttcact
   136621 atcacccata aatagtcaca ctccaagcta tgcgataaca ggtttgttgc cacacattct
   136681 actggttgat tgtttatggc tttatgtggc aacaaccagt acccttagct cagttggtca
   136741 gagcagacgg ctcataaccg tccggtcgta ggttcgagtc ctacagggta cattaacgta
   136801 gccatttgaa tcgttctgtg ttagaatttt tttgaagagt attatacaag ctaaagcttt
   136861 tcttcattgc cactcaaatg agtggctttt ttatgtatcc ttttatggat taatgaaagg
   136921 atgtttcaca tagttatact tctgtatatt tgaaaagttt tactttgatt tttaaataga
   136981 aagacatttg ggttaaattg tgagataata ataaagaaga gtttaaagcg caccccaaac
   137041 cacttcccca taagtgtgtt acgctttaaa ctcttttata tttgaagcca ttaaaaagca
   137101 taccatattt ttgaaaaaaa gtgagaaaaa aggcttacaa ttggagtggt agttaattag
   137161 tgacttattt ttgattttat agcactgata ctataaaata tagatatcat catattacac
   137221 aatcttaata ctaacttaaa aaatatctcc tttcacaagt atggtgataa aattcgttcc
   137281 gggctacctt tttaggtagc ctactttaat ctttatacct ttctggatca acgaaagtat
   137341 actttatata gtcataacgc cgatgatcgc tacgtgcgtc cggcacgtca gtcatgaatc
   137401 ggctacacta gactagacag aaaaaataag gtgtgtagaa taataaaaaa cacactggag
   137461 gatttttcat gtcaagacgt caacgaagaa cctattcaaa agaattcaaa caacaaatcg
   137521 tcgatctcta tctcgctggt aagcctcgcg cagaaattat tcgagagtat gagcttacgc
   137581 cttcttcttt cgataaatgg atgaagcaag cacaatcaac gggctcattc aaagaaagag
   137641 acaacttaac accagaacaa gcagaattga tcgcactaag aaagaaaaat aagcaactcg
   137701 aaatggagaa tgatatttta aagcaagcgg cgctgatatt cggacgaaaa gacaagtaat
   137761 tgatgccaac aagcataaat attccatatc agcgatgtgc aaaattctaa atatttctcg
   137821 tca
//
LOCUS       DAPBBV010000002       114421 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.002, whole genome shotgun sequence.
ACCESSION   DAPBBV010000002 DAPBBV010000000
VERSION     DAPBBV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 114421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 114421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.002"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..97
                     /locus_tag="RD486_000161"
     CDS             <1..97
                     /locus_tag="RD486_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7661930.1"
                     /translation="ILGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
     gene            complement(127..1443)
                     /locus_tag="RD486_000162"
     CDS             complement(127..1443)
                     /locus_tag="RD486_000162"
                     /inference="COORDINATES: protein
                     motif:HMM:NF014437.1,HMM:TIGR00826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7661931.1"
                     /translation="MRDDTKVDKAGLENLEDVKGTFNANGQFQVVIGPKVADIYEEVI
                     SQSGLSGANKEDVKKVAAELNLNWFQRAVKILGDVFVPILPAIVTAGLLMGLNNLLTN
                     PGIFFEQSLIEVYPNIADVADMINLIANTSFQFLPALITWSTVKYFKGNPLLGIVLGL
                     VFVHPDLMNAWNYGQAVTTGDIPHWTIFGLSISKIGLQAQVLPALVSGYVLAKTELFL
                     KKRVPETIQLLVVAPVAILFTSVITFIIIAPITIAIGNTIVAGIVWLFQKVPFIGGFA
                     YGIGLAPLVVTGMHHAFLPVHIQLMANGGDYIWPIGVMSSLAQGSAAIAMNFLIQNKK
                     LKGVGLAAGLSAYMGITEPAMFGVNLKYKFPFVVSILTSGIIGGFMASQHVIATSVGI
                     SGIPGFLSIPFEFWPIFFICMLASCVVSFGATYLYGKNKVLLQSFK"
     gene            complement(1535..1903)
                     /locus_tag="RD486_000163"
     CDS             complement(1535..1903)
                     /locus_tag="RD486_000163"
                     /inference="COORDINATES: protein motif:HMM:NF025668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin type III-like domain-contianing
                     protein"
                     /protein_id="HDT7661932.1"
                     /translation="MSYTTFSMSPISIKEKGKNCLKVTTTVSNKGSRDGYEVVQLYIG
                     AQYGRYIRPTKDLVAYKKVFVKSGDSVTVSFELTNKDFKYYDEEFNEIIDDGAYWIMV
                     GNDSSQALTNKEEIEVRINE"
     gene            complement(1895..2146)
                     /locus_tag="RD486_000164"
                     /pseudo
     CDS             complement(1895..2146)
                     /locus_tag="RD486_000164"
                     /inference="COORDINATES: protein motif:HMM:NF014026.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
     gene            complement(2990..6139)
                     /locus_tag="RD486_000165"
     CDS             complement(2990..6139)
                     /locus_tag="RD486_000165"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HDT7661933.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(6152..7369)
                     /locus_tag="RD486_000166"
     CDS             complement(6152..7369)
                     /locus_tag="RD486_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDT7661934.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWE
                     ERKLGELGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIER
                     KKWKPIKDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFE
                     TINLPRYSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLL
                     KETKKSFLQKMFV"
     gene            complement(7359..8954)
                     /locus_tag="RD486_000167"
     CDS             complement(7359..8954)
                     /locus_tag="RD486_000167"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HDT7661935.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            complement(9464..10246)
                     /locus_tag="RD486_000168"
     CDS             complement(9464..10246)
                     /locus_tag="RD486_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661936.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(10311..11147)
                     /locus_tag="RD486_000169"
     CDS             complement(10311..11147)
                     /locus_tag="RD486_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7661937.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(11165..12574)
                     /locus_tag="RD486_000170"
     CDS             complement(11165..12574)
                     /locus_tag="RD486_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7661938.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(12588..14411)
                     /locus_tag="RD486_000171"
     CDS             complement(12588..14411)
                     /locus_tag="RD486_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7661939.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(15254..15580)
                     /locus_tag="RD486_000172"
     CDS             complement(15254..15580)
                     /locus_tag="RD486_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661940.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(15626..15988)
                     /locus_tag="RD486_000173"
     CDS             complement(15626..15988)
                     /locus_tag="RD486_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDT7661941.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(16025..16240)
                     /locus_tag="RD486_000174"
     CDS             complement(16025..16240)
                     /locus_tag="RD486_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7661942.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            16367..16702
                     /locus_tag="RD486_000175"
     CDS             16367..16702
                     /locus_tag="RD486_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7661943.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(16778..18775)
                     /locus_tag="RD486_000176"
     CDS             complement(16778..18775)
                     /locus_tag="RD486_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661944.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(18873..19148)
                     /locus_tag="RD486_000177"
     CDS             complement(18873..19148)
                     /locus_tag="RD486_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7661945.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            19380..20114
                     /locus_tag="RD486_000178"
     CDS             19380..20114
                     /locus_tag="RD486_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7661946.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEKFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            20153..21295
                     /locus_tag="RD486_000179"
     CDS             20153..21295
                     /locus_tag="RD486_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7661947.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(21390..22781)
                     /gene="sufB"
                     /locus_tag="RD486_000180"
     CDS             complement(21390..22781)
                     /gene="sufB"
                     /locus_tag="RD486_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDT7661948.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKAVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(22786..23256)
                     /locus_tag="RD486_000181"
     CDS             complement(22786..23256)
                     /locus_tag="RD486_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HDT7661949.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(23243..24478)
                     /locus_tag="RD486_000182"
     CDS             complement(23243..24478)
                     /locus_tag="RD486_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7661950.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(24475..25761)
                     /gene="sufD"
                     /locus_tag="RD486_000183"
     CDS             complement(24475..25761)
                     /gene="sufD"
                     /locus_tag="RD486_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDT7661951.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(25774..26547)
                     /gene="sufC"
                     /locus_tag="RD486_000184"
     CDS             complement(25774..26547)
                     /gene="sufC"
                     /locus_tag="RD486_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDT7661952.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(26744..27592)
                     /locus_tag="RD486_000185"
     CDS             complement(26744..27592)
                     /locus_tag="RD486_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDT7661953.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(27616..28302)
                     /locus_tag="RD486_000186"
     CDS             complement(27616..28302)
                     /locus_tag="RD486_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7661954.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(28295..29329)
                     /locus_tag="RD486_000187"
     CDS             complement(28295..29329)
                     /locus_tag="RD486_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7661955.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(29392..29648)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(29724..30062)
                     /locus_tag="RD486_000188"
     CDS             complement(29724..30062)
                     /locus_tag="RD486_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HDT7661956.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(30064..30420)
                     /locus_tag="RD486_000189"
     CDS             complement(30064..30420)
                     /locus_tag="RD486_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDT7661957.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(30426..31613)
                     /locus_tag="RD486_000190"
     CDS             complement(30426..31613)
                     /locus_tag="RD486_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7661958.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(31804..32649)
                     /locus_tag="RD486_000191"
     CDS             complement(31804..32649)
                     /locus_tag="RD486_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7661959.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            32883..33848
                     /locus_tag="RD486_000192"
     CDS             32883..33848
                     /locus_tag="RD486_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDT7661960.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            34225..35268
                     /locus_tag="RD486_000193"
     CDS             34225..35268
                     /locus_tag="RD486_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDT7661961.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(35330..35794)
                     /locus_tag="RD486_000194"
     CDS             complement(35330..35794)
                     /locus_tag="RD486_000194"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDT7661962.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            36040..36987
                     /locus_tag="RD486_000195"
     CDS             36040..36987
                     /locus_tag="RD486_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7661963.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(37198..39270)
                     /locus_tag="RD486_000196"
     CDS             complement(37198..39270)
                     /locus_tag="RD486_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7661964.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(39203..39580)
                     /locus_tag="RD486_000197"
     CDS             complement(39203..39580)
                     /locus_tag="RD486_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HDT7661965.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(39709..40287)
                     /locus_tag="RD486_000198"
     CDS             complement(39709..40287)
                     /locus_tag="RD486_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7661966.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            40419..41711
                     /locus_tag="RD486_000199"
     CDS             40419..41711
                     /locus_tag="RD486_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7661967.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(41771..42889)
                     /locus_tag="RD486_000200"
     CDS             complement(41771..42889)
                     /locus_tag="RD486_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HDT7661968.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(42903..44324)
                     /gene="arcD"
                     /locus_tag="RD486_000201"
     CDS             complement(42903..44324)
                     /gene="arcD"
                     /locus_tag="RD486_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HDT7661969.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(44570..45691)
                     /gene="mnmA"
                     /locus_tag="RD486_000202"
     CDS             complement(44570..45691)
                     /gene="mnmA"
                     /locus_tag="RD486_000202"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDT7661970.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLIYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            46095..46694
                     /locus_tag="RD486_000203"
     CDS             46095..46694
                     /locus_tag="RD486_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HDT7661971.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(46832..48118)
                     /gene="efmA"
                     /locus_tag="RD486_000204"
     CDS             complement(46832..48118)
                     /gene="efmA"
                     /locus_tag="RD486_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HDT7661972.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(48389..48733)
                     /locus_tag="RD486_000205"
     CDS             complement(48389..48733)
                     /locus_tag="RD486_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HDT7661973.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(48870..50015)
                     /locus_tag="RD486_000206"
     CDS             complement(48870..50015)
                     /locus_tag="RD486_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7661974.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(50195..51169)
                     /locus_tag="RD486_000207"
     CDS             complement(50195..51169)
                     /locus_tag="RD486_000207"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDT7661975.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(51249..52124)
                     /locus_tag="RD486_000208"
     CDS             complement(51249..52124)
                     /locus_tag="RD486_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HDT7661976.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            52254..54161
                     /locus_tag="RD486_000209"
     CDS             52254..54161
                     /locus_tag="RD486_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HDT7661977.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(54702..57980)
                     /locus_tag="RD486_000210"
     CDS             complement(54702..57980)
                     /locus_tag="RD486_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HDT7661978.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(58251..58796)
                     /locus_tag="RD486_000211"
     CDS             complement(58251..58796)
                     /locus_tag="RD486_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7661979.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(58808..59500)
                     /locus_tag="RD486_000212"
     CDS             complement(58808..59500)
                     /locus_tag="RD486_000212"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDT7661980.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(59519..59803)
                     /locus_tag="RD486_000213"
     CDS             complement(59519..59803)
                     /locus_tag="RD486_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7661981.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(59816..60379)
                     /locus_tag="RD486_000214"
     CDS             complement(59816..60379)
                     /locus_tag="RD486_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7661982.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            60607..61269
                     /locus_tag="RD486_000215"
     CDS             60607..61269
                     /locus_tag="RD486_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDT7661983.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            61393..62589
                     /locus_tag="RD486_000216"
     CDS             61393..62589
                     /locus_tag="RD486_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDT7661984.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(62690..64066)
                     /locus_tag="RD486_000217"
     CDS             complement(62690..64066)
                     /locus_tag="RD486_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7661985.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(64103..64969)
                     /locus_tag="RD486_000218"
     CDS             complement(64103..64969)
                     /locus_tag="RD486_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HDT7661986.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(65058..66083)
                     /locus_tag="RD486_000219"
     CDS             complement(65058..66083)
                     /locus_tag="RD486_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7661987.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(66101..66775)
                     /locus_tag="RD486_000220"
     CDS             complement(66101..66775)
                     /locus_tag="RD486_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7661988.1"
                     /translation="MAKIMVVEDEEIIRQLVMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(66959..67852)
                     /locus_tag="RD486_000221"
     CDS             complement(66959..67852)
                     /locus_tag="RD486_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7661989.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(67926..69623)
                     /locus_tag="RD486_000222"
     CDS             complement(67926..69623)
                     /locus_tag="RD486_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7661990.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(69616..70929)
                     /locus_tag="RD486_000223"
     CDS             complement(69616..70929)
                     /locus_tag="RD486_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDT7661991.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(70929..74447)
                     /locus_tag="RD486_000224"
     CDS             complement(70929..74447)
                     /locus_tag="RD486_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDT7661992.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(74740..75198)
                     /locus_tag="RD486_000225"
     CDS             complement(74740..75198)
                     /locus_tag="RD486_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7661993.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(75495..76013)
                     /locus_tag="RD486_000226"
     CDS             complement(75495..76013)
                     /locus_tag="RD486_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDT7661994.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(76015..76632)
                     /locus_tag="RD486_000227"
     CDS             complement(76015..76632)
                     /locus_tag="RD486_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HDT7661995.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(76629..77483)
                     /locus_tag="RD486_000228"
     CDS             complement(76629..77483)
                     /locus_tag="RD486_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7661996.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(77480..78391)
                     /locus_tag="RD486_000229"
     CDS             complement(77480..78391)
                     /locus_tag="RD486_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7661997.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(78432..79766)
                     /locus_tag="RD486_000230"
     CDS             complement(78432..79766)
                     /locus_tag="RD486_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7661998.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            79974..80804
                     /locus_tag="RD486_000231"
     CDS             79974..80804
                     /locus_tag="RD486_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDT7661999.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(81048..81366)
                     /locus_tag="RD486_000232"
                     /pseudo
     CDS             complement(81048..81366)
                     /locus_tag="RD486_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(81488..81682)
                     /locus_tag="RD486_000233"
     CDS             complement(81488..81682)
                     /locus_tag="RD486_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662000.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(82187..82372)
                     /locus_tag="RD486_000234"
     CDS             complement(82187..82372)
                     /locus_tag="RD486_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662001.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(83222..83563)
                     /locus_tag="RD486_000235"
     CDS             complement(83222..83563)
                     /locus_tag="RD486_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7662002.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(83563..83793)
                     /locus_tag="RD486_000236"
     CDS             complement(83563..83793)
                     /locus_tag="RD486_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7662003.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            84080..84418
                     /locus_tag="RD486_000237"
     CDS             84080..84418
                     /locus_tag="RD486_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662004.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(84623..84862)
                     /locus_tag="RD486_000238"
     CDS             complement(84623..84862)
                     /locus_tag="RD486_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HDT7662005.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(84838..85185)
                     /locus_tag="RD486_000239"
     CDS             complement(84838..85185)
                     /locus_tag="RD486_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HDT7662006.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(85917..86498)
                     /locus_tag="RD486_000240"
     CDS             complement(85917..86498)
                     /locus_tag="RD486_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7662007.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(86681..87307)
                     /locus_tag="RD486_000241"
     CDS             complement(86681..87307)
                     /locus_tag="RD486_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7662008.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(87329..88660)
                     /locus_tag="RD486_000242"
     CDS             complement(87329..88660)
                     /locus_tag="RD486_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HDT7662009.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(88815..89216)
                     /locus_tag="RD486_000243"
     CDS             complement(88815..89216)
                     /locus_tag="RD486_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDT7662010.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(89302..89508)
                     /locus_tag="RD486_000244"
     CDS             complement(89302..89508)
                     /locus_tag="RD486_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662011.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(89603..91105)
                     /locus_tag="RD486_000245"
     CDS             complement(89603..91105)
                     /locus_tag="RD486_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDT7662012.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(91123..91578)
                     /gene="argR"
                     /locus_tag="RD486_000246"
     CDS             complement(91123..91578)
                     /gene="argR"
                     /locus_tag="RD486_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDT7662013.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(91676..92293)
                     /locus_tag="RD486_000247"
     CDS             complement(91676..92293)
                     /locus_tag="RD486_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDT7662014.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            92515..93888
                     /locus_tag="RD486_000248"
     CDS             92515..93888
                     /locus_tag="RD486_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7662015.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            93963..95075
                     /locus_tag="RD486_000249"
     CDS             93963..95075
                     /locus_tag="RD486_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDT7662016.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(95147..96784)
                     /locus_tag="RD486_000250"
     CDS             complement(95147..96784)
                     /locus_tag="RD486_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDT7662017.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(96952..97560)
                     /locus_tag="RD486_000251"
     CDS             complement(96952..97560)
                     /locus_tag="RD486_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7662018.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(97944..99095)
                     /gene="queG"
                     /locus_tag="RD486_000252"
     CDS             complement(97944..99095)
                     /gene="queG"
                     /locus_tag="RD486_000252"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDT7662019.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(99114..99866)
                     /locus_tag="RD486_000253"
     CDS             complement(99114..99866)
                     /locus_tag="RD486_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662020.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(100007..100957)
                     /locus_tag="RD486_000254"
     CDS             complement(100007..100957)
                     /locus_tag="RD486_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDT7662021.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(100958..101797)
                     /locus_tag="RD486_000255"
     CDS             complement(100958..101797)
                     /locus_tag="RD486_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7662022.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(101794..102540)
                     /locus_tag="RD486_000256"
     CDS             complement(101794..102540)
                     /locus_tag="RD486_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7662023.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            102778..104148
                     /locus_tag="RD486_000257"
     CDS             102778..104148
                     /locus_tag="RD486_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7662024.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(104203..105099)
                     /locus_tag="RD486_000258"
     CDS             complement(104203..105099)
                     /locus_tag="RD486_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7662025.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(105213..105383)
                     /locus_tag="RD486_000259"
     CDS             complement(105213..105383)
                     /locus_tag="RD486_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662026.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(105380..106057)
                     /locus_tag="RD486_000260"
     CDS             complement(105380..106057)
                     /locus_tag="RD486_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDT7662027.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(106148..107053)
                     /locus_tag="RD486_000261"
     CDS             complement(106148..107053)
                     /locus_tag="RD486_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7662028.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTGESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            107228..108682
                     /locus_tag="RD486_000262"
     CDS             107228..108682
                     /locus_tag="RD486_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7662029.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPTLSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVASASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            108698..109729
                     /locus_tag="RD486_000263"
     CDS             108698..109729
                     /locus_tag="RD486_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7662030.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            109736..110923
                     /locus_tag="RD486_000264"
     CDS             109736..110923
                     /locus_tag="RD486_000264"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HDT7662031.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            111079..112461
                     /locus_tag="RD486_000265"
     CDS             111079..112461
                     /locus_tag="RD486_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDT7662032.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            112433..112819
                     /locus_tag="RD486_000266"
     CDS             112433..112819
                     /locus_tag="RD486_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662033.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(113019..113687)
                     /locus_tag="RD486_000267"
     CDS             complement(113019..113687)
                     /locus_tag="RD486_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDT7662034.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(113876..>114421)
                     /locus_tag="RD486_000268"
     CDS             complement(113876..>114421)
                     /locus_tag="RD486_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HDT7662035.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSLVQFRKTTVTVV"
BASE COUNT        32990 a        23925 c        20079 g        37427 t
ORIGIN      
        1 cattctagga ttatataaga aaacccgaaa agaaggcact ctcttcgggt tttcggtctg
       61 tactgaaatc aaggtattat tgggaatccc agcttaaatc atagataccg taagggattt
      121 tattctttat ttaaaacttt gcaacagaac cttatttttc ccgtaaaggt aagttgctcc
      181 aaatgagacg acacaacttg ctagcataca aataaagaat attggccaga attcaaacgg
      241 aatagacaag aaaccaggaa ttccactgat accaacagaa gttgcaatga cgtgttgtga
      301 cgccataaat cctccaatta ttccagaggt cagaatggaa accacgaatg ggaatttata
      361 ctttagatta accccgaaca ttgctggctc agtgataccc atataagcag acaaaccggc
      421 agccagtcca acacctttca actttttatt ttggattaag aaattcattg caatagcagc
      481 agaaccttgt gccaaacttg acatgactcc aataggccaa atataatctc caccgttcgc
      541 catcaattga atatgaactg gtaaaaacgc atgatgcatc cctgtcacga ctaatggcgc
      601 aagaccaata ccataagcaa atccgccaat aaatggaact ttttggaata accatacaat
      661 acctgcgaca atcgtattac caatagcaat tgtaatcggc gctataataa taaatgttat
      721 aacactagta aaaagaattg caactggtgc aacaaccaac agttggattg tttcaggcac
      781 acgctttttc aagaatagct ctgttttagc taacacatag ccggaaacta gagctggcaa
      841 tacttgtgct tgtagtccta tcttagagat ggacaatcca aagattgtcc aatgtggaat
      901 atctcccgtg gttactgctt gcccgtaatt ccaggcattc atcaaatctg ggtgtacaaa
      961 gactagacct aacacaatcc caagaagagg atttccttta aagtatttta cagttgacca
     1021 tgttattaac gcaggcagaa attgaaagga agtgtttgcg ataagattta tcatatcagc
     1081 gacatcagca atattaggat atacttcaat gagtgactgc tcaaaaaaga ttcctgggtt
     1141 tgttaataaa ttattcagtc ccatcagtaa accagctgta acgatcgctg gtaaaatcgg
     1201 cacaaataca tcacccaata ttttaactgc acgttgaaac caattcaaat tcaactcagc
     1261 cgctactttt ttaacgtctt ctttgtttgc cccactcagc ccagattggc ttataacctc
     1321 ttcatagata tctgctactt taggaccgat aacaacttga aactgtccat tagcattgaa
     1381 ggtacccttc acatcttcca ggttttccaa tcctgcctta tcaactttag tgtcatctcg
     1441 caaggcaaac ctcagacgtg tcacacagtg agtcagtgct gcaatattct cttttccacc
     1501 aacaaagtta atgattgatt tagcttcttc tttattactc attaattctt acctctattt
     1561 cttctttatt agttaatgct tgagatgaat cattgcctac catgatccaa taagcaccat
     1621 catctataat ttcgttgaac tcttcatcat aatacttaaa atctttgttt gtaagttcaa
     1681 aagaaacagt cacactatcc cctgacttaa caaaaacctt cttgtaggct accaagtctt
     1741 ttgttggtct tatataacga ccatattgag ctccaatata tagttgaaca acctcataac
     1801 catctctact tcctttattt gaaacggtag tagtcacctt caaacagttc ttacccttct
     1861 ctttaatgct aattggtgac atagaaaaag tggtataact caacccatac ccaaagggaa
     1921 attgtggttc attggataca tctaagtatt tggtcgtatt aaacttttca cttgaatacg
     1981 gtctaccagt attgaaataa ttataataaa tagggatttg tcctaaatgt ctcggaattg
     2041 ttattgtaag ctttccggct gggtttattt tgccacaaag gacgtccaaa atagcattgc
     2101 cagcctctgc tcctagatgc caagcctcaa ctaatccctt acatatagat ttttaaatta
     2161 cacactagtt taaactaaaa caaacaagga aaaacttacc atttaatcaa aaaattagct
     2221 catatgaata tattagaatg taaattagac tggtcaaaat ctggtcaaaa aagaggacga
     2281 atacaggtag tcctcttttt tgttattttg atattctaaa tcatttttta ttggattatt
     2341 cccttgttcg atatagaccc aaattgatct atcaataatt atcaaactga gtcatataga
     2401 gacaaaaatt tcaaaaatga cctgttaaat ggtcatcgaa tatcatttaa aatcaatacg
     2461 acggagtcag acacggagtc aaaacaagcc cgctgagagt aaaaaatata cagtcccata
     2521 ggtaaagtgc cacaggactg tatatttttt tatttgagat tacctgaaat gattccattt
     2581 aatttttatc tcattttttc ctactagtta gtatcaaata ctctcctatt ttctcaataa
     2641 actattttgg gttacatggt atctgaaaca gctaaaacct tgtcattata gcaaaaaatc
     2701 actttatctc cgtttcattt cagatacatt tcacttaagc ggattccaaa aaaacaaaag
     2761 aaaaaggaac ccctagttag cctatgcttt ttattggttc ctctcaaaac acggtcatat
     2821 aacaacgggg tggggtaaat gaatgaaaaa ggtggaggaa acattattca atagctgtct
     2881 taaatacttc gttataaaat gtgaacaaat aaaagacatc tatccctatt ttctacactt
     2941 ccacttgact accatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
     3001 cattctcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
     3061 gtgggtattt aaatggcttc gcttctggat gtttggcttt atatccttcg taatccttac
     3121 tgttgataat tgctttcata ttaggaattg gatcttcacc tggtagatat tgcagattag
     3181 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaagacatga atcaaatcat
     3241 cactcgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
     3301 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
     3361 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
     3421 ttcctagtaa ttgatcaata taagttgaat caatatcata caacttagtg gtattttcac
     3481 tataaaattc gatcgttgaa aaatcttctc cttctttttc tggttcttcc tctattaatg
     3541 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
     3601 aagttggaga tttcaccatg tcatcattgt aatcgtcata agtcactaac gattcataag
     3661 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
     3721 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgt ttgaatcttt
     3781 ttttggattc ctgataactt ggataaatca aacctgattc ttcttttgct tttgaataca
     3841 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg cttacgaaac gtcacaatca
     3901 atccttttgt cttatcagga tacgtacgat tcgtacgtga aaaagcttgg atcaatcctg
     3961 catactctag attacgatcc acaaataggg tttgaatcgt aggggcgtca aaacctgtta
     4021 atagacgatc cactacaatc gctaaatcga tttgtttccc aaattgtttg aattccgctc
     4081 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctaatgacc
     4141 aggaagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     4201 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt ggaaaatcag
     4261 gatcctccat cgttcgtcct tcacgaatga gctgattggg aaactctttt gttaaccaat
     4321 caggctcttt cgtcatctct ttgatggccc gataatactt tttggccatg tcaatggaac
     4381 tcgtggttaa gattgcagat ttcgttggcc tgccatttcg aaaatcaaat tttgtatagg
     4441 cattatctgg acggaacatt ttatgaatga ctttttggat atgttcatct gcttcaaaaa
     4501 cagctgggtc caaataactt tcttttttga caggttccat ttgatcaatc atacgattga
     4561 tctgttctga tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     4621 tctctagtga agtcggctcc acggtgtttt catgctctac ttgaaatcct aagacagagc
     4681 catcttctag cgcattctta atggtatagg tatgcaagac ctctccatac tgatcatggg
     4741 ttgtacgtgc caattgccct ttggcttgtt tccgattctc aggaaaaatc ggtgtacctg
     4801 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     4861 ttaacgctcg atgacactca tctactacaa acacgatatg ttggcccatt aatttttgga
     4921 agcgattggt tccttttttc tcttcttgtt tctttgcata tttcaacgcc gcatctagtt
     4981 tttgacgggt tgtaatgatt acaacatttg cattggcatc tgccaacagg gtttcactta
     5041 attctttggc acttcccgtt ccaacgatca agctattcgc tttggcgttc ccggaagaaa
     5101 tcccagtatt aaattccgaa gcaaattttg taaactctgt ggtggtttga ttatctaaat
     5161 ctttgcggtc cactaacatg atcgttcgat cgatccccga ttttcgtgct aaaagcttag
     5221 tagatacaaa actagtcaac gtctttcctg aaccagtcgc atgccacaca taccctgatt
     5281 gatgtttatt tgcggcaata aacaaggctt gaatcgcatg tacttgataa ggatgtaaca
     5341 ccatgagggt tttattgtct tgatcttcac tgacgattgt ataatccgca atcaaacgat
     5401 gagcatccgg gatatttaac acttgtttac aaaactcata taagttttct actttttcat
     5461 tgtctttcgt tcgccaacta aataaaaact tagggtgcaa gtctttcggt aaggcatttg
     5521 caaaataccg agtggtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     5581 tgttccgaaa cataccttct tctgcatatt ttttgatttg gttaaatgcc tgataaacac
     5641 catcttttgc agttacttgt ttcagctcga tttggacaat cggtaatcca ttgattaata
     5701 aggtgacgtc aaaacgtcga tcccgtgctt ctatgttact tccacgtttt gcaatttgat
     5761 ggaccacttc ataagtagag attcctccac caatgtcttg attggaataa aggataagtg
     5821 agacagaacc caattgcgaa tcttcccgtt caatcgtgat ccgagccatc ccattttcac
     5881 cttttaacca tttcgcagca tcaaatgggg ttttcgttcg cagcagtaat tccgttttga
     5941 tcgtttcaaa ttctttatcg gtcaaaggaa aatcattcag ttctgcttga ttatttgaga
     6001 taattttttg gcgtaaattg acccaaaggt cttcttctga ttttagatcc ggacgatacg
     6061 tccactgatt atgcccttct ccaagtacac gaatcaactg ttcttcgact tctgcttcct
     6121 cacggtgact aattttcatt cttcttccct cctagacaaa catcttttgt aagaagcttt
     6181 ttttcgtttc ttttagtaaa tctaacttac gttgatgaag agcgatcgta tcatctagct
     6241 gtttgaagaa agtaccgatt ttttgttgtt catcctttac aggaacctta acactgatat
     6301 tctcaatatc agaactgtta taagaaggca atgcccctac ttgggagtat cttggcaaat
     6361 ttatagtttc aaacaatatt ttaccaaaat agatatccca agtattatta aataaataag
     6421 ccatggtatt gttatctatt aagaaagggc ttgtgaccaa acgttttcta ttaagcatta
     6481 ttgctgcgcc aactttagca aatataatcg ctggcacatc ttttattggc ttccattttt
     6541 tacgctcaat ttgctcatta gatacataat gatttgcatt tctcatttca tactcattac
     6601 caatgttatt catgtcggaa actttaaaaa atggagtacc ttcagaacca ccttgctcgg
     6661 catcaggaaa tccaattccc gattgagttt tacctaattc tcccaactta cgctcttccc
     6721 aatcttccgt aaaaccagga aaccggattt ctggcacttt tgctccgttt tcagggaaca
     6781 ttttttgtaa gaatcctttt ttcgtttcct tcagcaaatc taacttacgc tgatgaagag
     6841 cgatcgtgtc gtcaagttgt ttgaagaagg tgccgatttt ttgttgttct tcctcactag
     6901 gaaacattgc tactatattt ttaaactttt ttagagacag aacatgttga cctgttccct
     6961 ctgcttgaat agataattgt cgttggattc cattgttaat acgtcttaag aagaagtcgg
     7021 aatcagcaga ttttaaagta aatacaggat aaaaatagct tataatccct ctatcaataa
     7081 tgtcattacg gttaaacaca aacacatcat tatcacttcg actacggaac gtgaaatatc
     7141 ctctaggtag tacaaagtaa ccaatattat tttctgtagt tacttgccga tttgcaaaat
     7201 agtcttcttg caaaactatc cctttttgtt gagatgaagt tagcatagga aattgatttt
     7261 gtacacttgt cttttcaaca taatctacaa cgaagtcccc caacttcctc tgttcccaat
     7321 catctgtaaa tcctgggaaa cggatttctg gttgtgtatc attgctcatg tttgaacacc
     7381 tccagcgcac cttgtaacca cgcttcattt tcaggtgttg tttgcaggga agagatagct
     7441 tctaaaagtt ttttttctag cacttgctgt tcttgtcgta tcttcttgat gtcatttccg
     7501 acatgaacca tatcaattgg ttcttcttct tcgaaagtat ctacatagcg tgggatattt
     7561 aagttatagt cattttcttt gatttcatca aaggttgcca aatgagcgta tttctcgaca
     7621 tcttttcttt cagcgtaggt ttcgaggatt ttttgaatgt tttcttccga tagtttattt
     7681 tgatttttcc ctttaacaaa ttcacgacta gcatcaatga ataatacatc tcgagtttga
     7741 cgattcttct tcaacacaat caccgtcgtt ggaatcgatg tcccaaagaa caagttcgca
     7801 ggcataccga tcacagcata aatactgcca tcttctagta atttttgacg gatgacccct
     7861 tctgcagcgc cacggaataa aactccgtgt ggtaagacga tggccatggt acctgtttcc
     7921 ttcaaatgat agaacccatg aagaagaaac gcaaaatctg ctttggattt tggcgctaat
     7981 ttcccataac gattaaaccg agaatcatct aagaaagtcg tatctgctga ccaattagcc
     8041 gaataaggtg ggttcattac tactgcatca aatgtgtaag gttcatctgt tggccagtcc
     8101 ttattcaacg tatccccatt gcggagattc atttcttcgg cgtcgacacc atgtaaaatc
     8161 aagttcattt ttgctagatt gtatgtcgtt gtatttagtt cttgcccatg atatttaacg
     8221 ttatctgggt gtgttaagta gttacgtacg tttaacatca atgaacctga acccatcgtt
     8281 ggatcaaaaa cactaaagaa tcgtcgttcc ttttgatcga gcgttacgat ttgcgccatc
     8341 atatcagaaa ccatatgagg tgtgtaaaat tctccggctt tcttccctgc ttctgaagca
     8401 aattgactga tcagaaactc atacgcatcc ccgatcacgt ccccatcgtg ttctaaaaca
     8461 tctacatcat tcaatttctt gatgacttcg gtaatcgtca catttcgttg ttgctcatct
     8521 gttcctagtt tttttgattg gagatccaca tcatcaaata acccattaaa ttgattgtag
     8581 gtagatgcca attgcacaaa ggctttgttt agatcgttca attggaacgt tgcttgtttt
     8641 gcttgatccg ctaagacgtt gaaaagatac tctggtgcaa ttgcatatcc caaaatatca
     8701 acgattgtgg caatcagatc ttcttttgat tcttcatctg aaagtaattc acgatacaac
     8761 attgtttgtt tgcttactgt gtcatattcc tctaaggatt catctgctaa aagaaccact
     8821 tgttccaaca atcgatcgga taaatattta tagaaaatca gtcccaataa ataattttta
     8881 tattctgacg catccatttt actacggaga ttatctgccg cactaaataa tttttgattt
     8941 aattctgcac ccaaaaagat acactcctat ctcttattta aagttgctat ataccctctt
     9001 attttagcat accccctttt ataaaaagca aaaaaaaaaa gaaagaaact tattcttgct
     9061 aataaactac gcgaaaggag tctaacgttg tttgatataa cttagactga tcgttaactt
     9121 attttttata tttctacata gttatcttta gaaccatttc agatacatat gaaacaatta
     9181 catatgattt tttcataaaa aaacagtact gtctagtagt ataaaatata caaatttctt
     9241 aaaaattttt tcactaaaat cactacctga aacagtctaa aacacttata tatcaacgtt
     9301 taatgaaact atctccgttt catttcagat acaaataaat atagtcgggc tccaaatccg
     9361 aaaaaaaata cccccagtag cttatcctaa gctactggag atgtataagt acggtcatat
     9421 aacaacgggg tagggtaaat aaatgaaaaa gatggaagaa tcattattca ataacttttt
     9481 taaatacttc gttgtaatca gttacctgtc cgttcttaaa taccacagaa taatcttttt
     9541 tcccattttc aagtaaccga agtggaatgt ctttaccaac ttgctctgtc actgcattac
     9601 tgatacctgt tagattagct aataaatctg ataaagattg agcatctgta gaaatctctg
     9661 tatcagtatt tatcgtgatt cctttatctt catttacaag cttccaagta ggtggtatag
     9721 ctgtgtatgt ttcgatgaat gaatcaattc tttcatctat cgtcttccca gtatctactt
     9781 ctgtctcatt actcttagat gaatcgattc tttcatccat cgtctgctcc gtaactgctt
     9841 ctgtctcatt attctcaccg gaaactctct tcacacccaa acttatatat tgtccatctt
     9901 tagtgtgcat agttaaaatt cccacgcttt tactaataaa ttcactataa ccagttcttt
     9961 caatagagac ttcaatgtat ttcacactat catactcaaa agaaaaatag acatgtaaaa
    10021 gcattttgtt gtttacatct acataataat cctttgactc tacttgagac cttcctatac
    10081 ggaatacagc tttactgtct gatatctcta taccagcatc cttattatta atctgccaat
    10141 ctccaagtag ctcttctggc aagctagtag tttcttgtga acactttacc acttcactgg
    10201 tagaggtcga aacattcacc tccgcactgt tagaagaatt ttccaaggaa tcaggagcct
    10261 tagcacaacc aacaagtctt tatatattgt gcagccgata ttttcttcat tcagtacacc
    10321 cttgaaatat gcagtgttag ataaagcagt tcgtcctgat ttgctgaggc acccatctct
    10381 tcttgaacgt actccttgat tttcaaggcc gcccgatact ctttcggaaa acgctgcttc
    10441 actgaagcca gcaaaaaatc atccttctcc ggcaactctt ccttcttaat cattcgggca
    10501 ataaaaaact gtaaatgcgt cacaaatctt aagtaaagca tcgaatcttt atcaaccttt
    10561 ttttcgggaa acagatatcc tagcatagcc aagatatcct ttagtgctct taccgagagc
    10621 atggtttctt ccatatttgc ttgttcactt tgggcattta caatgtgaaa cgcaatgttt
    10681 ccagcctcct cttctggcaa ctgaacattc atttttttgt tgatcaattg gatagcatag
    10741 cagccgatct caaattcttt tgggtaatac ttttgaattt caatcagcag gcgattttga
    10801 aaaacaatgc ctttttgact gcgttcaatg gcatgcttca agtgatcaac caaggtaaaa
    10861 aatagacttt tattcagctt aaagtcaaac ttggcgttgg cataatcgat aattcgcttg
    10921 acgcaaataa ttagatcatc cggagcagcc tcaaacagtt taatgtaatc cttttttaga
    10981 gcatcagaaa gtgaatctaa tttaaatact ttttggattt tgtcagccgg aaccaaatcg
    11041 cctttcttta gttgaaatcc aatccctttc cccatcaaaa ttacttcttt gccttgctta
    11101 tctaagcaaa gaattaaact gttgtttaac gttttaatta ctctcattag attcaccgtt
    11161 ctctctaagc taagccattt cttgcgatta ctttttgata ccaaaagaag ctttcttttt
    11221 ttattcgttt taattcttta agattctcat cggttcggtc aacatatata aaaccataac
    11281 gcttattgaa gccttgatgg gtactaacaa catcaatcgc tgaccaaggt aaataaccaa
    11341 aaacatctac accatctgtt aaagctgctt gaatagccag aatatgtttg gctagataat
    11401 caattcgatc ctggtcatta attcgtctat cttcctcaac tatgtcgggt gccccatagc
    11461 cattttcagt aattaaaata ggtaaatcat agcgatcgta caatttcctc aatgttaatc
    11521 gtagtccagt agggtcaact acccagccat atggcgtttt atctacataa ggattttcag
    11581 ctgcccggta gacaccttct tctcccaaca tgatctgttg atcccccgct ctagcggaaa
    11641 catctgatcc gtcatttttg ctggcagcga tggtggcagt tgaataataa ttaatcgcaa
    11701 taaaatcggg tttaccggag gataaaattg cctgatcctc tgcctcaatt ttaggatata
    11761 atccacgatc attcaaatag ttttcaaaca aataattgta ttttccccga actgctacat
    11821 ctaagaaaga ccagcctctc aatgtttccc aattatgggc tgcaattgca tcttctggac
    11881 tggaggtagc ttgatacata gccgttaaat tgattgctgg accgattttt cctttaagat
    11941 tcaactgatg atacaagtga attactctag cttgagctaa taaaacatgg tgattaattt
    12001 gaaagagttc tttttttgaa ggcagctctc cacttggtgg caaaccaatc gctccaggat
    12061 gaaggatcat cgtgttttgc tcattaattg tcagccaata gttcaccttg tcaccatact
    12121 cagtaagcaa tacctgtaca tagtccacaa aataatcgat agttgctcga tttaaccaac
    12181 cgccctgctc ctctagaaaa taaggtaaat cgaaatggta catggtgaca atcggttcga
    12241 ttccctgatt caggcattca tcaattactt gatgataaaa agaaattccc ttttgattgg
    12301 ttttattatt ttcaatatcc ataattcgcg tccaagcgat ggaaaagcga aaagctttta
    12361 agcctaattc tttaaacagc tgtatatctt ctttatagtg atggtaaaaa tccgaggcaa
    12421 cttcaaaatt agctacccct tctgtatgct gatacttgtc aataatagac ggttgtttcc
    12481 catcctcctg ataggcaccc tctgcctggt aggcactaat ggaggcaccc cataaaaact
    12541 tctctggaaa tgctgaaagc tgtttgtatt gcacaaaaat cctctcctta actaatttgc
    12601 atcaatggtt cgtgttcctt taagcttccg cttgcttcac taattcctgc gtaattttca
    12661 ctgttggtca ctaccacaat cactgtatca tcgtagccag cgtttctaat ggcagcgaaa
    12721 tcggcgttga ttaataattg tcctgctgac acctgatctc ctgcttttac aaatacttca
    12781 aagggttccc cttttaaatt cacggtgtcg atccccacat ggatcaataa ttcaatacct
    12841 tctttagaac gtagaccaat cgcatgttta gattctaaaa tagtaatgac ttctccctca
    12901 acaggtgaat aaatgctgtt ttcttctgga tgaatggcta cgccctttcc caatagtccc
    12961 ttagaaaaga cagcatcgtt cacttcagaa ataggacaca cggttccttt taccggattt
    13021 tcaacaatga ctgcttcggc tattgccgtt tgctctgatt catcagaagt atcgtcaaat
    13081 ccaattagat aagcaatgat aaaggttgca acaaaggcga ttacacacgt aataattgcg
    13141 tgaacaatat tcattggatt ttctccaata aaggctggta aggctgctaa gccaggggaa
    13201 acaaaggcat atctgactaa accgctcaag ccagcataca aaccagcaat tgcaccacca
    13261 atcatggaag caactaatgg ttttttcagc ttcaaggtta ctccatagag tgaaggctca
    13321 gtaattccca ttaaagcagt gatcccagtg gacacagcta gctgcttcaa ctctttgttt
    13381 ttagttttcg cggctacagc aaaggtagca cctgattgag caatattaga agccagcatt
    13441 cctggcccat tgatcatttc agaacccgta ctgctcaatt gcatagtagc gattggcgtc
    13501 attgcccaag ctgtacccgt aaccaccaaa aatggctgca aaccacccat caaaaatgga
    13561 attaaccaag ctgctttgcc gttaatccat tcagccccca ttgctataag atcgttcagc
    13621 aacgttccaa acggtccaat gacaaccaac gctaaaggcc ccataattaa aaataccagc
    13681 atcggcttag taaagaattt aataaacgaa ggcgaaattc gatccgcaaa gggctctaca
    13741 taggacatga tccaaacagt aaagataatc ggtaaaactg atcccgcata atctgcagct
    13801 aataccggaa ttcctagaaa agaaacggca tcgccagtag aaaaaagctg tgaaatattt
    13861 ggatgaagca aaatgccagc aacagtaatc gccaaaattg ggttgacatc aaactttatg
    13921 gctgccccat aggctaatag tactggcata aaataaaagg ctgcatcagc aatagtattc
    13981 aaaatgatgt aagtttgact actgtctgat agtacaccag tcaaagtcaa gacggccaaa
    14041 atggctttta ccatcccggc acctgttata gctggaatca tcggtgtaaa ggtggtagaa
    14101 atgacactaa tcaatcttga aataatactt tcttgattgt ctgaagaggg gcccttttta
    14161 attgaagttc ccacttcctt ttgaatttcc ttgaaggctg tttggacttc attgccaatc
    14221 accacttggt attgtccacc gctatccacc acactaatta caccaagtgt tttttctaag
    14281 gctttcgtat cggctttcct tttatctttg agttcaaaac gcagtctggt ggcacaatgg
    14341 gttaagctga ccacattttc ttttccccca acctgttgca atacatttct tcctacttct
    14401 ctgtaatcca ttattctctc tccttaaagc agtaaaaaag accaagtcaa accacgcccc
    14461 aatcaacatt gaagtgttag tttgtcttgg tcttgcctgc ataatcagta acatgccaat
    14521 aacgttattt tgctgtaatc caataatagc acattatgat agcgcaatca acagggaatt
    14581 taatttttta tcttttcgtt tgaccgtata gggtaatata acagttagat cacatcaact
    14641 agggtatatc tgcgtatact tactgctaaa ataagtatat ctaatattaa ctataccagt
    14701 aaaaccattc ctacataacc agcgggaaat tcccaaaatc gtgaaagcat caaaaatgca
    14761 tataacggat cacacaactt caacaattct gctcttggga aaaattgatg aatttggtga
    14821 gtaaaggatg gaataaacag cattccaaca atataggcaa caatagtgat acttgttttt
    14881 ttggtaaaaa tcagtaagca atagccaatt tcaatcattc cgagatataa aggtatcgat
    14941 agaatgattt gggctagtat tcttaaaaat taactagcaa atgtttaaac tgatttattt
    15001 ctaatctaca tgtagtaagt atttcaattc caccaattat caataaaaat accaaacata
    15061 tccataataa ttttttcttt ttcatttctt ttatattgtt ataacagtga ataacataaa
    15121 aattcccgac aatcattgta atattttttt gtcacctgta ttagtattta atttatagga
    15181 aactataaaa actccctagt gaatttacac ctttgggagt tcctgtttgg acggtatgca
    15241 taatacattt aaatcaattt aacattaaca cctcagcata tggtatctcc acatatatac
    15301 ggtctttctt tggatagtac tcaatattta tgttgatagc acttccattg tctaatatag
    15361 ctttagcccg gtatgtgtta tctccatttt catgagtaat cgtcacatca tcacatgatc
    15421 gatttaagtt gtactgttct tgtaaaatct gtgttaccaa tggttttgat gacttctcta
    15481 atccagatgt acctgtcatt tttgaaaaaa taatacctat aatagccaag acaacaatac
    15541 ctataatgac aaacttcttg ttcatattta ctttattcaa ctttttatct cctatctcca
    15601 aaataatttg ctcttatccc tcttatcagt acattgacat ccctaaaagt acaccaaaga
    15661 ttgctccagc tacccctgct atcatcaaaa tcgtacccat tttctcatct ttttctcgat
    15721 ataagtagcc cataataaca gcaacagcac caaatacaac aggaataaat gctaacgata
    15781 ctaccataga aatccaacca ataatcaaat acagcttccc tgtctcttgt ccatgtacga
    15841 tttgttcctt catttcatta attgtctgct cagtactttt ctttactgtg tctgttccgg
    15901 ttgtctcatc tgtttcttgt agtgctccac aaaactggca atacttactt tcatctgtta
    15961 tttctttgcc acattttcta caatacatgt cttctcctcc taaaatcatt caattgctta
    16021 ttagttaact gtttacttta ttaaatacat cagaaaacag ctcattcatt ggtacactta
    16081 atatctcaga aagcatcttc atttgatagg gtttaggaat cgttctccct gtttgccacg
    16141 aacttacaca ttgctgtgta acattcattt tttttgctaa ctccgtttga gaaagtcctt
    16201 tttcttttct gtatcggctg agattactta cttttttcat gattctcccc tcctgtttta
    16261 ttatatacaa caatatgatg tatttcaact cataaaatat aaaaaacttc aaataccatt
    16321 acaaatacaa caacttgttg tactatactg agatgggggt gtattaatga aacagaaaca
    16381 atatgcaaag gtcattagag aaaagcgaaa agctctcggg tggacacaaa aagaattagc
    16441 tgaaaaaatc ttctctacac aacaggcagt agcaagatgg gaaaattctg taacagagcc
    16501 taacctcgat agcttaacag ctctttctag agccctagga acccctgtaa gccattttct
    16561 agacaatgtt gtcgtagatt atgaggaaga gtttttggct ctctatcgtt ctcttagcac
    16621 tgaagatgca gttcgaacaa ttgactatat gaagctatta aaaaggcaag aaaatgaacg
    16681 caatcagcta ttgaaagatt gaaaaataaa taacccaccg aactttaacg gtgggtgtat
    16741 tgagatgaaa taagattaag agctatggat aacctgtcta gtttaataca attgggtctt
    16801 ttctcttcct tactctccgt ccatcatctc ttgttacact tgtaaattga tacagaggaa
    16861 ctatcccagc tcctgataat atcaattctt ttattgtttc atctatccct gcccctttcg
    16921 ctaaatatat taaaaaacta ctacttgctt tcacattgta tagtttctta atatccttag
    16981 aagctcgttc aagagtgaat ccttgtttaa caaagtagcc tctgtttttt attaaagcat
    17041 ttttcacgct gttatcccca acattacgta ggcgttcaca aacagtgtta ataagttctt
    17101 tctctgtcat tagatatgtc ccttgccacg ataagccctg taaaacttca tgtgcttcat
    17161 ctaaaatcaa ttgtttttcc ttgctgagtt ctgatcggga attttgagga aatactcttt
    17221 tagcctcttt ttcgttaaaa catatcttaa cccattcata agaaaaatat tgatatgtaa
    17281 aatgaatttt ttccagaagt ggaaggatat cttcattcaa tttttgaatc acagaagttg
    17341 cattaaaaac gtctaatcga tagacattgc ttctcttatg attaaagttt cctaacgctt
    17401 tctcttcctt taacctattt aggtattcga gcatcttcaa aggaacatct tcatcatcta
    17461 atttttttat caatcctata aaagtcataa gtgatagtaa cttattacat ttatctatgt
    17521 cataagtttt accatagtaa gaactcattt ttttagctaa ttgttccccc gacaaaatac
    17581 aagtcacact ttccttacta tcatcaaaaa aattaacatc agaaagcaag acatcataga
    17641 cacgtcgcat ttcctctaga taattcctta ttgtcctgaa aagtttgtct ttcattgatt
    17701 caagagtgtc aaaaagtact tttgattcct ctttcaattt tcgaaaatgt gtaggataca
    17761 agtctaggtt ctctaatagc caattaaatg tttctacccg actgtctttc tttaaaatta
    17821 gcatcacaac tccaataaaa ttttcactga tatcacaatt actggaatga caataaaaaa
    17881 tggaatgccc agttttactg gtaaaaatac tagcagaggg attatgatcg ttgtgaaaca
    17941 gacatcttaa gtttttactt gacttaagta atttattcat atcaatggtt aacaatcttt
    18001 cataaatctc attaaaagac atgtcggagg aatcaaacag gcagtcttta aaccactgtt
    18061 tcatttcttc tttgtcgtca ttttttatca acttaacaaa atcggtttca ttgactagtt
    18121 catactctct ccctgaatca ctttgacaat ttttagaaca tgtcatggta aaatcaatcg
    18181 gaagctcagt aatatctaac atgttgtctt cattaattat tatcactgca tctgacttat
    18241 atcctccaaa aaacattcta ttcgaagcat ttacattgtc atcacacccg gggatgttct
    18301 ttttcaagta ttcgtaaaca gcaaccattt taccatagtc agtaattgct tcttttaata
    18361 gaaagacaat cttgtatttt tctagatttt cagagtaccg aatacttttt tgtatcgcaa
    18421 acgcagaatt atgaactaaa ttgatagata aaaccttttc tacgcttaag tatctactat
    18481 catctttact caaatctact accttcccct tctcatcttt aacagtgtta tcgacatcca
    18541 gaataattac tctggtttcc acaaaactct ccttgtcatt gcctttattc tttgtcttgc
    18601 ttggaataaa tgattgtgat gaatttagta tctctacaaa ctcatctctt gtaacttctc
    18661 tatagttatc taaacaccta tctcttacat cagttttttc tttttttgta actggcttct
    18721 ctaataattt ttcttgatct acataaattg gaatattaat cattgatgtt tccatttgtg
    18781 tttcctcctt ataaaattct gttaaagact aaaacataca gataataaaa acaaactctt
    18841 tattactata tgttttagtc ttatttgttt actcaacctt tataccgttc catgaaacta
    18901 tcaatatcag attttttaaa tctaatgacc gtatcaattt ttataacagg taacccgtat
    18961 tgagaaacat attttctaat cgttcctact gatacaccta gatattcact tgcctgctga
    19021 tagtccatat actctagagt gactccagaa ataatgtctt ctagcatagg ctttagcact
    19081 gtaattatct ctttcacttg ttgttcaact tgtatagaaa caatgctatc aatgatttgt
    19141 agagacatat ttccccctcc tttcgtgatt gcttgaacaa attttctaag aattatcttc
    19201 gtattttttg ctcaaaataa aagtattttg ttattaaccg attaatcaaa caaaaaatga
    19261 ttaccagttc atcgacatac acataatacc tcgataaaaa aggggtgtca acatctttgt
    19321 aaaatttatt tacaacaccc cttttttgag gtatactaat tttaggaggt gtggtcaata
    19381 tgataaaacg tccaccaata aattatttag aacgaaaaaa gatactcgga acaaaaataa
    19441 aagctataag aaagagtaaa aaattaacac aaccagcatt tggtcttatg attaacaacg
    19501 gtcaattaat tgacaaaaaa actatctacg aatgggagaa gggaacctat ttaccaatac
    19561 cagagcgatt atcccgaatt gctgatttgg gaaatatgag tatagaggag ttagtttgtg
    19621 gcaatgtaga agaatatatt ttgggaatta ttctttatag agatagcatt gtactagatg
    19681 gtataacatt tccagataaa aacctgttcc agcatcttcg tcaacagttc ccaccagtac
    19741 actctaattt agatacatgg ctggatagat attccaaatt agaaccagag atgcaagaat
    19801 ttattgctaa caagacttgt aataaagtta aaaatgaaaa aattagtctt ttcaatatct
    19861 taaaaataga agaattattc atcaatgcta ttgtagaaaa atttgacaat aacattcttt
    19921 tcctcactag cagtatagaa gaactactag aaagaatggt agatgaatgg ctacctattc
    19981 aattgaaaga catgtcttat cccgaagaag ctgtgagaga aattactgat aatataaaca
    20041 agctagaaca aacgatttca tcaattggga aaaaatacac taagaaaaaa atgaagggag
    20101 gtgataccat ctagtggtaa gtactccttg taaactaaga ggagatgatt taatggcaaa
    20161 aatatcaaag tacaaaaaga aaaacggtca agtggcgtgg atgtataaag gacacattgc
    20221 caccgatcca cgaactggtg aaaaaataaa tactacgaga agaggtttta gtagcaaaca
    20281 agaagctcaa aaagattatg acgagtacag acatcaaata ttatacggtg ttaaaaagaa
    20341 agcacctgat atgacatttg aagacctgta taatgaatgg ataactcatc agcgtaccag
    20401 tgttaaagct tcaacaatcg caatctcagt aagatacgca aataatcaaa tacttccagc
    20461 atttggtaag cttaaactat cgaatatctc tgtcccatat tgtcaaaaag tggtagatga
    20521 atggcacagt aaatatgaaa gttacgatta tatgagaaaa cagactgcac aaattttacg
    20581 ctacggggtt gcaatgcaat atattgacaa taatcctatg gaaaaaacac ttcttccacg
    20641 aaaaaaagag tatgagaaaa atcgtaaatt ttactcaaaa gaggagctta ataatttact
    20701 ggatgctttt aaagattttg gtaacatgaa acaatacgcc ttcttcagat tattggcata
    20761 cacaggtatg agaaagagtg aagtactcgc tttacagtgg aaagacatag acacgtttaa
    20821 taaagaacta catgtcaata aaactcttgc tgtagatgaa tttggtaaag ttataattca
    20881 atctccgaaa acaagagctt ctagacgagt tatctcttta gatactgaga ctctttctat
    20941 cctcaacaac tggaaattac agcaaaaaga agagtattta aaacttggat acaatactag
    21001 ctctaaagag caacatgttt ttacaacagt taaaaacact ctatacattc caaacactgt
    21061 taatgattgg ttaagatata ttttgaaaaa atataacttg cctcgtatta cacctcatgg
    21121 gtttagacat acacatgcta gtttattatt agaagcagga gaatctgtca aggtagttca
    21181 acaacgatta gggcatgaaa atagtaaagt gacattagac atctatgcac atattacaaa
    21241 taatgcacct aagaaaacag gtcaagactt tgctgatatg atggctcatc agtaaaagag
    21301 ctggtcaaaa tctggtcatt tctagtatac aggcaaaaca aaaaagctag aacccttata
    21361 tatcaagggt tctagctcct ataacaggtt tacccaacac tgccttccat ctcataactg
    21421 atcaatcgat tgagttcgac tgcatattcc attggaagtt ctttggtgaa tggttcaaca
    21481 aagcccatga cgatcatttc agttgcttca gattcggtca ggcctcggct catcagatag
    21541 tagagttgtt cttctgagat ttttgagact ttggcttcgt gttctaaaga gacttggctg
    21601 ttgtggatct cattgaatgg gatcgtatcg gatttcgacc attcgtccat gatgatcgtg
    21661 tcacattcga tatgagagat cgaacccgca ctgtttttgg caaaggttac ttgtcctcga
    21721 tagtttactt ctccgccgtc ttttgaaatt gatttagaga cgatagagct agatgtattt
    21781 ggtgcattgt ggatcatttt tgcacccgta tcttggattt ggtttgctcc tgcaaaggcg
    21841 atggagagca tggtgcctcg tgcacctttt ccatctaagt aaacacttgg gtatttcatc
    21901 gttgtttttg cacctaggtt tccgtcgatc cattcaacgg ttgcgccttc gtatgctttt
    21961 gctcgtttgg ttactaagtt gtacacattg tctgaccagt tttggatcgt tgtgtaacgg
    22021 caatacgcat cttttcttgt aaagatttct acgatggcgg catgcaggct gttacttgaa
    22081 taagtaggtg ccgtacaacc ttcgacatag tggatgcttg ctccttcgtc aacaatgatc
    22141 agcgtacgtt cgaattgccc cgtgttttcc gcattgatcc ggaagtacgt ttgtaatgga
    22201 acatcgactt tgacggcttt tggcacgtaa ataaaggtcc cacctgacca tacggctgaa
    22261 ttcagcgctg ctaatttgtt gtcggttggc ggtacaagtt ttgaaaagta ctctttgaat
    22321 aattcagggt attctttcaa agcagagtca gtgtcagtaa agacgattcc taacttttcg
    22381 aattcatctt tcatattatg gtacacgact tctgattcat attgtgcgga agcaccggct
    22441 agataagctc gttcagcttc tggtatacca atcttttcaa atgtatcttt gattttttct
    22501 ggtacgtctt cccagtcacg agcgggtttg tcacttggtt tttggtaata tttgatggca
    22561 tcgaaatcga tgtctgaaag gtcggggccc catgtttgca ttggcatttt gttaaatgtt
    22621 tctagagatt tcagacggaa ttcaagcatc cattctggtt cgcctttgat tcttgacatc
    22681 tcacggatca cttcttctgt caagccttct cctgtactga aaaccggttc gacatcatcg
    22741 tgaaacccga atttatattc ttctaattct ggtacgccca tgttctcact cctcttcctt
    22801 gtggtaatga tggaaagctg cggtaccatc gttttccatt gcttttccta gtgctttcca
    22861 ggcaagtgtc gcacatttga tccgagcggg aaatttagct acaccaccaa gcatagcagc
    22921 atcgcctaat tggtcgggat ctttgacttc ttttccttgg acaagctgta gaaagtctac
    22981 agttaaatgt tctgcttctt ctattgattt tccgatgacg gcgtctgtca tcatcgaggc
    23041 acttgccgta ctgatggagc agccactgcc gtcaaaggcg atatttttga tgattccgtc
    23101 ttttacatcg acttgcaatt cgatcacatc tccacatgtg gggttgttca attcgatctt
    23161 gcttgtcgag tcagtcaagc ttccacgatg atgcggatgg gaagaatgat ccaagatcac
    23221 ttgacggtat aaattgtcta atttagatag tcccatgttg gaaaaactcc tttgttgcca
    23281 tgattgcttc aactaaacgg tcggcgtctt gcgttgtgtt gtagaaataa aagctcgcgc
    23341 gagcagtcgc tgatacttca aggtacttca atagcggttg cgcacaatga tgacctgctc
    23401 tgacggctac cccttccatg tctaaagctg tcgcgacatc atggggatgt aacccatcca
    23461 aattgaatgc aacgactcct gtccgaaaat tcgggtcttg tggaccataa acagtcaatc
    23521 catcaattgc ttgtaatttt ggcaacacat aagcggctag ttcttcttca tatcgatgga
    23581 tattgtccat accgagtttt tgcaaataat cgattgcatg gcctaatgcg atagcgccgg
    23641 cgatatttgg tgtccctgct tcgaatttcc aaggtagttc tttccatgta ctgtcgtata
    23701 attcgacaaa atcgatcatt tcgccaccaa attcaacagg ttccatttct tctaaccatt
    23761 ttcgtttacc atataaaaca ccaatacctg ttggtccgca cattttgtgt ccgctgaaag
    23821 caaagaaatc acagtctagt gcttggacat caatggccat gtgcggggca gattgagcac
    23881 catctactac gatgaccccg ccgttttcat ggacaagttc agctaattct tgaacaggat
    23941 tgaagacacc taagacattg gatacatgag caatggagac gattttggtt ttgtccgtaa
    24001 tctttttcgc tgcatcctcc atatccagga agccttcttc tgttagttcg atatatttca
    24061 agacagcacc tgttcgtttt gccaactgct gccacgggat aacattagaa tgatgttcca
    24121 tgtaagagag cactatctcg tctcctgctt tgatatagcg gtcgccgaag gttctggcta
    24181 cccaattcaa gcttgtcgtc gtaccacgag taaacagcac ttctgctgtt tcttttgcat
    24241 ggatgaacgc ccgtactttt tctcttgctt gttcataatc atgggtcgcg cgttctgcta
    24301 acgtatggac accgcgatga acattggcgt tatcgtgttc gtaatagtac gctaatgcct
    24361 ggagtacttg ttttggcttt tgggtcgtcg ctgcattatc cagataaact aaaggttcat
    24421 cattgacgtc ttgaaataag ataggaaaat cattgcgtag ctttttagca tcgatcatcc
    24481 attcaacttc ccttcgatta cttcgactaa ttctttccga acttgttcta cagggattgc
    24541 tgttaagaca gaaccgagga atcctcgaat cactaagcgc tctgcttctt ctttatgcaa
    24601 tcctctactc atcagatagt acatttcttc tggatcaact cgtcctacac tggcagcatg
    24661 tccagcagtt acttcgtttt catcgatcaa aagaatagga ttcgcatcac cacgtgcttt
    24721 atcagaaagc atcaagacac gactttcttg ttgggcatct gcaccttttg cccctttcaa
    24781 gatgtggccg ataccattaa aggtcaatgt tcctttttct cggatcactc cgtgttgcaa
    24841 aatatgcccg atcgtatgag gggctttatt ggttactcgt gtatcgattc cttggatttg
    24901 tctgcccgag ctgattgcca cgattttgac ttctgcgtgt gcaccttctc ctgctaaatc
    24961 tgagtcaaag tcagcgatca catgaccgtc attcatgaca ccaattgccc agtcgacaga
    25021 agcatctcgt aaaatgtgcc cacggcgatt catataagaa gtaatatttt ctcctaattg
    25081 atctacggct gaatatttga tttttgaacc agctttagcg atgacttcca cgatgatatt
    25141 acctgatgat tttgctactt gttctttggt tgtctggaaa cgttccagat aagaaaattc
    25201 actatgttca tctgccacga tcaacacatg cttgaagaag tgctcatcgg atgcgccatc
    25261 ttgaatgaat aaggactcga gtggttcatc gatcacgaca tttttaggca catacaggaa
    25321 aataccgctg ttcataaaag ctacatggag tgcagtcaat tggtcttcgt tcatgtttac
    25381 tgcttttttc atataatatt cttggactag ttctggatat tcgatcattg cagtgaacaa
    25441 gtcggtaaaa atgactcctt tttctgctaa ttccacaggc agttgttcaa aaatcgtcca
    25501 tgaaccttgt tggacaagca caggattgtc tttcattgca tcaaatgccg gaatcgtgcc
    25561 tgtttcactg atggtttgtg tttctttcac atcaaataac gaccagcgat ggaatttcac
    25621 ccgatcgata tgcggcaatg gcagttcatc tgctttcgct agtgcgtctt gacggaaggt
    25681 tctcatccaa tcaggttcgc ctttacttaa agaaaaatca tttaccgcgt caagataatc
    25741 gagccagttt ttttctttca ttcttgctcc cccttacgct tcttcttctt tatagtcgat
    25801 tcctaattct ttactgatac cagcgtagcc ttctgcttcc agacgtttag ctaggtcagc
    25861 attccctgtc atgactactc ggccttccat catgatgtga acgacatcag gtgtgatata
    25921 gttcaataat cgttgatagt gggtgatgat caatgcaccg aaattgtctc cgcgcatttc
    25981 atttactcct ttagcaacga ctttcaaagc atcgatatcc agacctgaat cgatttcgtc
    26041 taaaattgca aatgtaggtt ctaacatcaa caattgcagg atctcattcc gtttcttttc
    26101 tccgccagaa aaaccttcgt tcagataacg ttcagccatt tcttctggca tatttagtaa
    26161 agccattttt tcatctaact ttttcaaaaa tgccataaca gaaattttgt cgttttcatc
    26221 acgtttcgca ttgatcgctg cacgcatgaa ttccgcattc gtgatacctg gtatctcact
    26281 tggatattgc atagctaaaa ataagccaag tcgcgcacgt tcatctactt ccaagtctaa
    26341 aacatttttc ccgtcaaaca aaatttcgcc ttctgttact tcatagtttg gattgcccat
    26401 gatagcggca gataaggtag attttcctgt gccgttaggt cccatgatgg catggatttc
    26461 tccggttttc attgttaggt ttacgccttt aaggatttct ttttcctcga tcgacacatg
    26521 tagatttttt atttctaaga cagacatgca ttataccccc aaattctctt tcgttctcac
    26581 tcattttaga ctaattgaga atgaagcgca atgaccttcc ttactaaaat caaatatctt
    26641 ttatttatta ttaaacaatt ttgatttcta aattagaata ggtataaaaa agatgagaaa
    26701 taagccatta cagacttatt tctcatcttt tttgttccat accttatttt gcatcagcct
    26761 ttactggttt aacagagccg ccccatttgt ctgttatcca ttcttggact tctttgcggt
    26821 gaagcacttc aatcagtttt ttgattttgt cactgtcttc atcaccttta cgagtcgcaa
    26881 taatattcac gtaaggagag ttgtcctttt caagcaatac ggcatcttct aatggattca
    26941 accctgcgcc gtaagcgaag tttgcgttga ttgcaactag gtcaccttca tcattttggt
    27001 acgtagaagc taaaagtgat gggtcgatcg tatggttgaa cttcaagttc ttagggtttt
    27061 cttcaatatc atcgaatgtt gctgtttcca gatctactcc atctttgact ttgactaagc
    27121 cagcatcttg tagaattgtg atgatgcgtc cccagtctga ttcagaattt gaagtaatga
    27181 ttgttgcacc atcttttaat tcggaaacat ctttgacttt tttagagtac aagcccattg
    27241 gttcgatgtg gacagcaccg gcattgacaa agtcatatcc tttttctttg atttctttgt
    27301 tcaaataagg aatatgctgg aagtaattgg catcaatgtc gccttcttcc aaagattggt
    27361 tcggtaatac atagtcatcg aatttgacga tttcaagatc gattccttca tctttcaata
    27421 atggtttcac atgttccaaa atctctgcgt gcggtgtcgg tgaagcgccg actttcaatg
    27481 tcgtgtcgtc tgctttattt gctgaatctt tgctgtcgct gttgttaccg catgctgcta
    27541 atcctacagt cagcaaaagc gctgctgcaa atccaaaaat tttctttttc atatcctaca
    27601 tccccctata tcctattatc ttttgtctgt tttcttagtt aagaaatcac cgattccttg
    27661 aacgataaat acgattagta aaataattaa agtcgcaacg aatgtcactg ttagattacc
    27721 acgctggtag ccttcctgcc aagcaagacc tccaagtcca cctgcgccga tcgcgccggc
    27781 catcgcagta aatccgatca tcgagatcgt tgtaactgtt aatccagaaa tcaatgcggg
    27841 aatactttca ggtatcaaga ccttccagat gatttcccag taacttgctc ccattgcatc
    27901 tgctgcttcc agtacaccag ggctgacttc acgaaaagca atctctacta gacgggcata
    27961 aaatggtgct gcggataaaa caagagctgg aatggctgct tgcgcaccta gcatagtgcc
    28021 tacgattgct ttagtaaatg gaatgatcaa aaccatcagg atcataaatg gcgttgaccg
    28081 gaaaatatta ctgatgatcg atacgattcc ataaatgatt cgagcatacg gtttgttttt
    28141 gcgtccaata gagtaaagga tcaatcccaa aactaatccg atgatcgtca ctaagaccat
    28201 tgagattaat gtcatatata gtgtatcaag gatagcctga ttcatcgttt ccgggttgat
    28261 ttgtttaaaa tctagatatg tttctgaaaa gcttttatcc acgatggatc acctcaattc
    28321 ctactccttg ttctttgatg aacacttctg cttgatctaa ttctttggtt tcaccagtca
    28381 tcaagacagt caatgaacca aaggaacctt ctttcacttg tttgatcttt ccatacacaa
    28441 cgttgacatc gatgttatag cgtcgaatcg cttgggaaat gactggctcg ttggcatttc
    28501 tttcgctaaa ggtcaaagtt gccaaacggc cgcttggatt ttctttgatg agttcagcta
    28561 atagttctgt cgaatcagct tctggttcga tgtcttgttg tacaaagcgt ttggttactt
    28621 cttttttcgg ttgtctgaag acagtcaata cgtctccttc ttctacgact ttccccaact
    28681 ccatcacagc gactttgttg cagattttgc ggatcacatt catttcatgt gtgatcaaga
    28741 cgatggtcaa attcaatttc ttattgatcg ctaacaataa gtctaatact tcttctgttg
    28801 tttgcgggtc caatgcgcta gtagcctcat cacaaagcag gatctcagga tcatttgcca
    28861 atgctcgtgc gataccgacg cgttgtttct gtccgccgga aagttgtgaa ggatatgctt
    28921 gtccgcgtcc ttctaacccg actaaacgca acagttcttc tgcccgttct ttacgtttgc
    28981 tctttggtac gccagctaat tccagcggca gctggatatt ttcaagtaca gttcttgacc
    29041 ataacaggtt gaaatgctgg aagatcatac cgattttctt tcggaatgta cgtaattctt
    29101 tgttttttaa ttttgtaata tcttgatcgt ttacgatcac ttcgccgctc gtgggaagct
    29161 caagtccatt caggagacgg actaatgtac tttttcctgc gccagaatag ccgacgattc
    29221 cataaatatc ccctttttca acgtttagtg aaacgtcatt gacggcttgg atgtttccgt
    29281 ttttcccatt gaatgtcttt ttgacattcg ttagttggat taatgacatg ccattcacat
    29341 ctttctctta tgatttttca aacaaaaaag ccttcgccct cttgccttaa gcaaaaggac
    29401 gaaagcttga acttccgtgt taccaccttg atttaccgtt acttcgcaat aacagcctct
    29461 tccagtactt ggacttagct tctttccgta tactgtcgcg ctgtaacggg cactcccgta
    29521 gtaagtttgc ttacgctcgc ttactctgct ctaagaccat cttccatctc attttcgtta
    29581 cccattttca gcaaacaggg ctctcttcaa acgtccgtga catgtactct tcttttcaaa
    29641 gctttctcgt ttcatatagg attgcttatg attatagcaa ctggaagaat cagtgtcaac
    29701 ttttttcaag tgattttctg attttataat tcgtcaaatt cttttggatc aacatctttg
    29761 aaacttaaga tccacgcatt catttcatct gaatcattca agatattgat atcttcaccg
    29821 attttatcat taacagaaga aactgtaccc gttagcgggc tggcaaattc attgaccgct
    29881 ttttccgctt caacttcgat cagaggttca tcttttttta gcgattgtcc tgcttttggc
    29941 agattggcaa acgtgatgtc tccaagttct tcttgcgctt catttgtcaa accaacacag
    30001 tattcttttc cattaaataa gatccaaagg ttgtcctttt tcttcaaatg cttgcctgcc
    30061 attttatatc agttctcctt cataaatttt ttcattgaat ccaattgcaa caagctggtc
    30121 ctctcgtaag atcagtggtc gcttgatcag cataccatct gtcgataaga cttggctcgc
    30181 ttttgaagcc gtaaactcgc ctacttgatc tttcagtcca agttcccgat atttcatccc
    30241 gcttgtgttg aacaggcgac ggattggtac ttgactcgtt tctagccaag tctcaatcgt
    30301 tgaggccttc ggtacttctt tgatcatatc aacggtttga taactaacgc catgctggtc
    30361 taaccacgct ttggcttttt tgcatgttga acatttcggg taccagtaaa aggtgtacaa
    30421 ttttcttacc tccttgaaga tcttgcaggt gcttcatttt ggtatctcat cgataatatc
    30481 aacccgatac cgatcatgtt ccctaaaatc gaggatcctc cctgactaat gaaaggcaat
    30541 gggatccctg ttaaaggaag taatccgata tttgctccaa tattctcaaa gacatggaac
    30601 agcagcatca tgatcaaacc gcttgcgata taggcgtaaa attcattatt cgtatcgaaa
    30661 cacacccgaa tcatacgata gattaaaata aaatacaaga aaatgacgaa tgcaccaccg
    30721 ataaagccga agttttcacc gataacggta aaaatcatat cggactcacg aacaggcaca
    30781 tagatattgc ttacgttgaa tcctttacca aacaagccac cggtaccaat tgccaaaagt
    30841 ccttgggccg gctgataact cattcctgac gtatcatgga aagggtccag ccatgaatca
    30901 atacgtgcaa actgataaga tttgaatcca actttataaa gcaagtctct tccgccttca
    30961 gtcgtaacca agaagatcgt tcctgctcca acgactactg ccaagattac tacaggtgcg
    31021 atgatgcgcc aagagattcc agacatcagg aaaatcccgc caaagatcgc aagaaagaca
    31081 agcatcgttc caaagtcatc ttgggccatg atcaatgcta aaaccggtat tgtcacgatc
    31141 aagagcttcc caatcagcca aaagtccgat ttcatcgtcc gttcttttac ttgcgtatta
    31201 tgtttagtta cgatcagtgc catcatcaag atgtacgcaa tcttcatcaa ctctgctggc
    31261 tggaaagtaa acgcaccgaa tcgaaaccag tttttagacc ctgttgaagc agctaaattc
    31321 tgatcataga atttgagcaa gagtcccatt accactaacc ccaaaccata aaggtaagga
    31381 gtcagtttcc agatccattt ggaattcaaa tgcatgatga caacgattgc tgccgctcca
    31441 actaaatacc agacaacttg catccctacg cctttcaaga ctgctggatt gttcggatca
    31501 tggctaagtg ctacatataa tgagagcaga ccaatcaaac ataacagaaa gactggtaaa
    31561 atcacgccat aatcaatacg attatcgttc gaagctttta attttttttc catgtttcat
    31621 cccttttctt aaaaaccata ctgctgatta ttatagcggt ccagttagat aatggaaagt
    31681 ctttccatag acatttggga aaaattaact ttccgtttgt gcagttgctt gagcaaatgc
    31741 agtacaaaag cctactgctt atctttagtg tatcatagaa ctttttttga tacatgcaat
    31801 tatctaccag ctgagattct cctcgctgtg agaagtttct gtgctttcat tgtatcgaag
    31861 gatctcttcg gcaatctcta gcagctgatc agaaaccaga ttggttcgtt ggatgaaata
    31921 aaaatatcga tggaaattca acggagtcat tggcacattt tctggaacag agcgcttaga
    31981 caaaatcgag cgaccgattc cttccttcag caacgcaaca attacatcgt tacttttcac
    32041 gatcatcttc ttatcttgga tattcatctc ttcaaaataa cgctgcgtgt aatgaaaaac
    32101 accagagttt gcttctctta caagccacaa tttgcttttt gggtccccag cgatgactag
    32161 ctggtcttcc atcaaagagt atctttgtac gccggaagtc tctaatggct tttcgataaa
    32221 accaaaatcg gattcatgtt tcgctacttg ttctaatgat tcatgagaat tcgtgatttc
    32281 gatctcaaaa tgcactttag gaaacctttt gatcagatgt ttcatcaact gaggcaaaag
    32341 atagacagca aaggtgtggg aagcaacgat ccgacatact tcttcttcat tttgttcatt
    32401 gagcaatttt tgctgagttt cttcccattc ttctaacaaa accagtgtcc gttcatataa
    32461 taagtcggct tgcttagttg gaagcatctc ttttcttccg ttacgttgaa aaagatcgat
    32521 attcaattcc cgctccaact gtttgatttg attcgagact gctggttgag ataaaaacag
    32581 tacttctgct gctctggaaa aatttcttgt ttcatatact gctcgaaaag tcgttaataa
    32641 cttaaacatg gcaccacttc cataactttt tatgataatt actataaaaa ctatttgatt
    32701 taaatataca aaaaaccatc tataatagaa atgtacaaca aaacagttgc tgatccaact
    32761 agtaacttag atgaagacaa tcagctgtct gcttgctcgt aatcatacat tcctattcat
    32821 tttacaatgt attcgttcat cttggtacta aaatctatta aataaaaagg agaatattat
    32881 atatgaagaa ctttttgaaa attattccga tcccgatctg cgggttgatc cttgggttag
    32941 cttcccttgg aaatctgttt aaagactatc accatgttgc tttaggcaat ctaactggcg
    33001 gtatctctat gattcttatg atattcattt ttgttaaatt gtttatctta ttcgaacaca
    33061 cgaaacaaac gttgcatgat ccaatcatcg cctccgtttc accaactttt acgatgtcac
    33121 tcatggttat ttgtacttat tttgtttcat atgaaagtat tgcaccaatt gtcaaattca
    33181 tttggctgtg cgctgttatc ttccaagtga tccttgtctt ttatttcaat tatcaccatg
    33241 ttatcaaagc tgatctttca attgaagcaa tttatccaag ctggtttatc atttacgttg
    33301 gatttggggt catcactgta actgccggga acttcttccc acttattgga aaaattttct
    33361 tttggatttc attgatctgc tatgcgttct tattgccgat catcatcaaa cgtgtctttt
    33421 tcgtaagaaa tatggctcat ccgacacgtc cgctgattac gatcgttgca gcacctggtt
    33481 ctctttgcct aacaggttat cttaaaaact ttgctgaacc taatttttat cttgtcgtag
    33541 cattgttcgc tttatctcaa gtattgtatt tcgttgtgct gtctatgctt ccacgtttgt
    33601 tcaagcttcg tttttatcca agctatgcag cctttacatt cccgcttgtt atctctgcaa
    33661 cagctatatt tactactgtt cattacttca acagtttagg tatctatagt agcgtattgg
    33721 atttcttaaa agttgcggaa tgtctgtttg caagtgtagt tgtcttctac gttcttgctc
    33781 attacgtacg tttcttaatt aaagaacata gcaaacatgg aaaatttgtt tctaaaaaaa
    33841 tcgcttaata atcgattcaa taggttgtga aaaagctgtt ctgcatcaag taataagaac
    33901 ggccaaacaa aaacagctgt tcatgttttt gtactggttg ggcttattac cgcagatgca
    33961 agcttttgaa caccgtttac caagaggtcg taaaagaagt ggtcagcttc aagaaataag
    34021 aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat ttccgtagaa
    34081 gctacttctg gaacaccgtt tattcgaaac aagaggtcgt acaagacttt tgtcacgacc
    34141 tcttgttctt ttgtcaaaat actggtttag tgctactatg ttcgagtatg cttttagtat
    34201 ttattgacga aaggaaccga tcaaatgaaa tcattgtcac atccaataaa atctgtaaag
    34261 gattcagcgg tccgcgaaat cttacccggt ttactgcttt cttttgccat cgctgccttc
    34321 agcaggcttc ttgctattta tctgccacag ttaggtggag cgactattgc tattttattg
    34381 ggtattttat taggaaatac tttttttaaa cagcctgttc tagcaatcgg cacaaaattt
    34441 gctgaaagca aactattaga attctctgtt tttttactag gtgcaactgt cacagctcaa
    34501 acgattgctc aaattggtgt aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact
    34561 atcatcggtg cttacttgat tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg
    34621 atggctggag gaaacgctgt ttgtggttct tctgctattg cttcaatcgc cccttccatc
    34681 catgcgaaag aggaagaaaa aggacagatc atcacactag tcaatctact gggtactgtg
    34741 atgatgttga ctctcccttt tcttggatta cagttgtttg gtggaaatct cattgaaaaa
    34801 agtgcacttt tgggtggtac actccaatct gttggtcaag tagtcgctgg ggcaagctta
    34861 cttgacaatt ctgttgtcga attcgccatg ctatttaaga ttctacgtat tatgatgctc
    34921 gttgttgttg tctatctgtt tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa
    34981 acgccaactg atacgcagaa aaaacgaaaa ttaccgcttc cttggtatgt attagggttt
    35041 gtgatctttt gtttggtcaa cagcttgttt tctttacctg tagttattga ccaatcggca
    35101 cattttatca gcagctggtt tgagatcact gctttagcgg caattggtct gcgtttagac
    35161 tttgcaaaat tcatgaaaga aggtacacgc ttcttatctt atggattagc tgtcgggctt
    35221 ctccaaacag tgatggcttt actatttatt tggctgatca aagtttagaa tgaacatgaa
    35281 aaaacagttg tgattctcgc atggaacaat gtccgaatca caactgtttt taattttgca
    35341 gatatccttc taacaacaac aattggcgtt tgatttcaac cccatctatt gcgtttccca
    35401 tatatcctgt cagttttcca ttttgcccga tcactcgatg acaaggaata acgattggca
    35461 atggattggt tcgatttgcc tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa
    35521 cggctacttc tttatacgtt cggatttctc cataaggaat ggtcgacaaa gctttccaga
    35581 cattttgctg aaaaggcgta cctctcttta tagataaagg aacatcaaat tcttttcttt
    35641 ttcccgcaaa atattcttca aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg
    35701 attcgctttc tgaaattggc tgaaaagata cagcagtcaa tccggattca tctgcatcta
    35761 accataaaaa gccgataggt gtgtgtattt tcattttgtt tgctcctagt caatagactg
    35821 gaacttcctc ctttttctct atccaaaact acttgccaac taataaaaat tgttcttaaa
    35881 agtttgataa accgaggaaa catggtaaac taaatacgtt agtttacaaa aagaatacct
    35941 gttcttttac gtaaaatcaa attttaaagg tgttatttaa ggtttattaa attttgaatg
    36001 taaaccatat ataaacatac gattgaaagg atagaaacga tgaaagtatc aattgttgtc
    36061 ccatgtttta atgaagaaaa aactgttcct cttttttttg atgaggttga aaaattcaaa
    36121 ggtgcccatg agttcgaata tttgtttatt gacgacggat caaaagacgg tacgttagca
    36181 gcaatcaaga agctagcctc agcttatcct tatgtccgct ttgtctcatt ttccagaaat
    36241 tttgggaaag aagcggctct gtacgctgga ttgcaagctt ctacaggaga tttagtgacc
    36301 gtgatggatg ttgatctgca agatccgccc gaactgcttc ctgagatgat caaccggatc
    36361 actacttctg atatcgattg tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg
    36421 atacgcagtt tctttgcgaa aaaattctac cagttgatca ataaaatcag cgatacagaa
    36481 atggtcgatg gcgctcgtga tttccgcttg atgactcgtc aaatggtgga tgccgtccta
    36541 gaattaacag aatacaaccg attttcaaaa ggattattta gctgggtcgg atttaaaaca
    36601 gaatatattt cttatgaaaa ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg
    36661 aaattattca actactcgat tgatggtatc gtgaacttct cggatgcacc gttaacgatt
    36721 gcttcattta tcggcgcttt gtcttgtgtc ggttctggta ttgcaatttt gttcattatt
    36781 ttgcgggcat tgttgtttgg tgatcctaca tcaggatggc cttccatggt ctcgatcttc
    36841 ctgttcattg gtggaatcca attgttatgt cttggaatca tcgggaaata tattgggaaa
    36901 atcttcttag aaacgaaaca gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag
    36961 ccaaatgaat tgaagcctca ccaataatat acgtcaaatg aagtaaacat ttttttaaat
    37021 gaaaaaggac tgtgacaaaa gtcttgtcac agtccttttt tccgaataaa tggtgttcca
    37081 gaagtagctt cttcggaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta
    37141 aattccttct tatttcttga agctgaccac ttctatcaca acctctttca tatcttatta
    37201 cttcttcatt gctgctttta gtgctgctgc taatgggctt tcttctggtt cttctgcttg
    37261 tgcatatttt ttcagcaagc gtcgttcttc atgtttggtc attttcttct tctgctcttt
    37321 tttatcaagc aatttttctg tcgttccatc gtatttacaa cggaaataag caccgttttt
    37381 accttcgatg atttccattt tccggtgaca ttgcgggcat cgatgattag agacttttgg
    37441 atcttttctt ctgcggtagt tgcaatctga attggtgcag acatagattt tgccgtcacg
    37501 tgtgtttttc tcgcgcagat tggccccaca ttctgggcat ttcttttggg taatcgagaa
    37561 atcttgatat tcttgtttgc ttgatttgat ctcattcacc aagcgttttg tttctttttc
    37621 gattccattc aagaaggttc ctgcttgttt ctttcctgca gcaatagctt caaggtcttt
    37681 ttcccagctt tctgtcaaat ctggtgttac taaagaggga tttaccaata ctaataattg
    37741 cttaccttta ggagatactt gcagtccttg aggggtacgt tccatcagtt cagatttgat
    37801 tagtttctcg ataatctctg cacgcgtagc tggggttccc agactgtatt tttccatttg
    37861 accaagcaag cttgcttctg acaatggttt aggcggtgca gatagttctt ttttgatggc
    37921 gaaatcggga ttgattctca ttcctttttc ccatttgact gtttccgtct cagtttcagt
    37981 ttcgcctttc catcctgctt ggacgacacg attttgccga aaaatgaatc gttctttacc
    38041 aaattcaacc gtaacttttg tttggctgac tttatggggt tgagcaaaca gtcctaaaaa
    38101 acgagagaca atcatttgat agatttttcg ctcttcatta cttaattttt cataacgtgc
    38161 tctgttttca gttggcaaaa gtgcatggtg atcggtcact ttactgtctt ggaatacttt
    38221 tgtctgttgg acgatggctc cgtttttcaa atactgcttg acctcaggag caaagtcgct
    38281 gactgcttgc aatcgttctt tcatcgtact tttcatgtca tttgtcagat atttgctgtc
    38341 tgtacgcgga taagtaacga tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt
    38401 tttctttgca gaatagccat agcgttgatt ggcttctctt tggatctctg ttaaatcata
    38461 aggcaatggc gcagattccg tttttaattt ttcttggact tctgtgacag ttcctttgct
    38521 tgtactgatc aattgaacaa gtttttgtgc ttcttcttgt gtttttaaag caaattgatt
    38581 tttttgaagc attttggctt gttcttttcc agcttgcaac gtgatcgtga aatacgtttg
    38641 tggacggaac tgctcgattt tcttttcttg gtctctcact aatgctagtg tcggtgtctg
    38701 cacacggcct gctgataaat tatccgcgta cttcacagtt aaggctctgg tcacattcaa
    38761 tcctaccagc cagtccgctt ttgcccgggc aagagcagat tcatacaatg catcatattc
    38821 tttcgcaggt cttagttgct tgaatccagt tttgattgct ttatctgttt gagaagagat
    38881 ccataaccgc ttcactggtt tattgaaatg cacatactct aagatccagc gagcaacaag
    38941 ttccccttct cttccggcat ctgtcgcaat gactgcttct gagacatctt ttcgctgagc
    39001 cagctgcttg attgctttta attgatgtcc tgttttagga agtggtttga ttcctagttt
    39061 tttagggatc attggcaacg tgtccatttg ccagctctgc cattccttat tcagatcttc
    39121 cggcattttc aatcctaata aatgaccaag ggcccaagta acgatcacct tgggtccttc
    39181 ataataattt ttgtgctttt gattagcacc aagcaccttg cttaggtctt tcgcaacgct
    39241 tggtttttcc gctagaatta gttgtttcat aaaattcctt tctgctttct actgtgatgg
    39301 gctgatgatt tttcaacaac gcaagtccct tgtattgctg taaatcatcg tcacactctt
    39361 cacaccagcg ctcatctccg tcattccaaa aggcgctgag aaagttactt tttgcattga
    39421 tatattcata attttgatgg atttcgttcc attgtttttc gtacgcttgt cgtgcttctt
    39481 cgaaagactc gaatgtttct tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc
    39541 aaggctcatt gtccccgaac atggtaatta cttgatacat actcgtgctc cttctttcag
    39601 cttttctaga ctcatcttag tcacttttca agaaagttgc aagaattttc tcttataaaa
    39661 gggtcattta atgaacatct taaaattgtt acaaatgaat ctgattgttt aaggcaaagt
    39721 agcgataaag ttattgatca tccaaaaata gctgtcttct ggatcgattg ttggttcttt
    39781 tgtaaagtat cctaaaaaac gtaaggaaag ataaccgtgg atcatactac gaagttccct
    39841 gcttcgatga actttttctt ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat
    39901 ctgattcgtt tcatggattc catctaataa aacagcttca ttggtatgcg gtacactgat
    39961 cagtaactca tacactgctt gatttgaaaa agcaaaggat cgataagttt ctgcatagat
    40021 ctgcagtgct tcctgaccac tttttcccac aagagcccgt cgcagctggt cattaagttc
    40081 ctgcagaagt ttcgctgtta gcgctgtttt gacatcacga atatttttga aatggttata
    40141 cagcgaggga gccttgatat ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac
    40201 atccatctct tctgctagtt ctcgaaagca gtcgatgatt ttctcttgag acagatttct
    40261 ttttttcatt tccatgtttc ctctcataaa ataaatcctt cactctttca gtttaccacg
    40321 aaaaagaaag agaaaaaaga gactttcatt gataaactac atattgtagt ttataataaa
    40381 gagctgtaga tgaaaatttt cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa
    40441 aattatttag gaaaagagaa acttgggaac aaaacttgtt tgtcttatgg tttggaacat
    40501 ttatggctgg tatcggattt agtttagtca tgccttttat gtcactttac atagatacgt
    40561 taggtaatta tagtacgtca caattgaact tttggagcgg attgactttt tcatctactt
    40621 tcttggtgac tacgcttatc tctccttggt ggggaaaatt agccgaccaa aaaggaagaa
    40681 aattgatgct gttgcgtgct tcattaggaa tggcaatcgt catttctttg atgggttgcg
    40741 tgactagtgt gtatcaatta gtcgcattgc gtctgcttca agggattttt tctggttata
    40801 tcagtaatgc cactgccctt gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc
    40861 ttggaacctt agcaactggt tctgttacag gaacattact tggaccgctt cttggcggga
    40921 tctctgcttc agcgtttggc tatcgcccta cctttttcat tacagggatc atcttatttt
    40981 tcgtcttctt gttgagtctg tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa
    41041 acatggtttc tgccaaacag attttcaaag acttgaaata tccacacgtc gtcatcggta
    41101 tgttcgtcac aacgatgatc atccaagcat ccaacaattc cattagtcca atcatcagtc
    41161 tgtacattcg ccaattgctg catggacatg ggaatgttac gttgatcagc ggaatcattg
    41221 cttcgatacc tgggattgcc actttgatag ccgctccaag atttggtcgc ttaggtgaca
    41281 agattgggag tgaaagaata cttgcgattg gtttgggttt tgcgattctg gtttatatcc
    41341 caatggcatt cgtcacgaat gtttggcaat tagctgcctt acgttttttg attggtatct
    41401 ctgatgcttg tctgctccct gctgtccaag cattgatcac aaaatattcg cctcatcaag
    41461 ctgctggacg gatcttcagt tataaccaat ctttccaagc aactggtaac gtagtagggc
    41521 ctatgatcgg ctccagtgtt tccagtgcat ttggttatcg tggcgtcttt ctttcgactt
    41581 ctcttcttgt tttggtcaac ttcttgcttg tacgacacaa tacacaagag atccatcagc
    41641 aagaaactgc agaagaaaaa gcttcaggag tctccatagc ttcagggcac tctccttctc
    41701 atagacaata agcgtaaatg aaaaacactg cttgaacagt tgtcacagac tgtccttgca
    41761 gtgtttttgt ttaggcctgt tttttcaaga actcagataa gaggaataat cccttttcca
    41821 aggtttcttt tttacaacag taacctagtc gggcatgctt cggtaaatca aaggcacttc
    41881 ctggtactaa tagtactcct gtttcttcta ataaattgat acaaaatgtc tggtcatctt
    41941 cttcgatggc taatttaatg aaagaagtag agacgtaatt gggagcgaca agttcaactt
    42001 tcggttcatt ggctacccat tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt
    42061 ttcgcgccaa tattttttct ttattcttca atgcatgtac agcaagatca tctgacagga
    42121 ctccgccgca aatcatcgtg tagtctcgat actttcgaaa aacttctgcc aactcaggtc
    42181 cagtagctgt ccagccaata cgaatacctg gaatggagta ggttttggat agggaattgg
    42241 ttgctatacc tttttcatag acatctacga tcgacaagaa ttcaccttta tccgttaaag
    42301 gcgcatatac ttcatctatc aatacatatg catctactgt acgagcaatt tctgcgattt
    42361 tttctaaagt tttccgatct agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga
    42421 tgatttttgt ttcaggtttg actaaggctt ctagctgttc taaatcaaac tgccaatctt
    42481 cttcttcctt caaatgaaca aagtcaacag cggcacctaa agatttgggg atgtcatata
    42541 attgctgata agtaggaagc atcgaaacaa catggtctcc tgcttccact aacgcgtata
    42601 aagctaaaag attagcacca gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg
    42661 tttgataaag agaagcgact tcttgtttga aaacatctga tccttcgatc cagccatagt
    42721 ccaatggttc gtttttgcgt ttttcgaaaa atttacttac gctagtccca tctaagccaa
    42781 cgagttcgtc taatgtcaat gcttcgatcg agctttgtgc aatatcatat accgctttct
    42841 tttcccattt atttagccat tcttctacac cgaaatttgc gattttcatg tttctttccc
    42901 ccttatatct tgatccagcc tacagcaagc aacccgattg aaagcagtgc ggccacacaa
    42961 atcagcccaa tcattacttt ttcttttccc gtaatttgat gtttggtttc acgacaagcg
    43021 atccagtaga agcaaaaacc aggaagatag gcaatactac ataaaaggac ataagaaaat
    43081 cctgctaaaa tgatgcccat caattcaaaa actacagcaa tcccaccgat cactacttgt
    43141 tttttgattc cttcttttaa agaaaactgg acttgataga tcccgacaag tagataacaa
    43201 atcaaaattg ccgctgtaca taaagaatag gcaaattgat aggcataatc agtaactaag
    43261 aaagtcaata agaatagatt agtcaagatt gcagtaacaa ctaacgaata agttggggca
    43321 ttttttttat tcgtttttcc ccaacctttc ggcaacagac cgtctcgagc catcaacatc
    43381 gttgtttctg ctgggagcat cgtccaagac aaccaagaac caatgatcga aataatcaag
    43441 ccgatattga tcagcgctgc tccccaattt cccacgattc cttttaaaat atttgccata
    43501 gcaggttgtg aaatagttgc taactcttct tgagataaga cgccgtatgg caagatcgaa
    43561 gcaaggatat agataaacaa taaacaaagc agaccaatga tcgatgcttg ctgggcttct
    43621 gaacgtttct tcgcgcggtt ggctaaaaca cttgcgcctt cgatccctac aaagacccac
    43681 atcataacca tcaaacaacc tttaatctgc aaccagatcg ttccttgctg ccctgttcca
    43741 ttcactagat tatcagatac gttaccccaa aaatcagcag tgaatatatt cactttaaat
    43801 gcgataaata caaatattaa aaataggaat aatggcacta atttacagat cgtcacgatt
    43861 gtattgatga cgctcgctcc ttcaactcca ttgtttacta ataaagtcag accccaaata
    43921 aaaatacttg caaataaaat agaaggaaca ttttgtccac ctttgaatat cgggaaaaat
    43981 tctcccatgg cgctcatcag catcgttgca aaagcaacat ttcccagcca cgcagacaac
    44041 cagtaacccc aaccactgat gaagccacct aatttaccaa atgaagcttc cgcgtaaccg
    44101 aaaataccac catctagatc tggacgcttt tctcctaaat gattcagcga taataccaaa
    44161 gctaaaatac caatcccaac gattatccat gaaaggatcg ctggccctgg agctgcagaa
    44221 ctagccagat cacttgtgat cccaaacaca ccgcttccga ttgacgaact gacaaccaga
    44281 gcaaccagtc cccatttgct aatacccgtc gatttctttt ccatttccat caccctcact
    44341 tataaaattg aacaaatcac ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt
    44401 aacaaaaagc aactttattc atattattgg atattatgaa ctttttacac aagtatttca
    44461 agtataaaat gaataaaaat taattttatt gcaaaaaaac agctatgcta tccaaaagaa
    44521 aaggtgtttc ttttgttagc catagctgtt ttgattcatt taatatcgct taaacgtatt
    44581 gtaaaacttt tgtttcttga tatgcgtggt cgatcaaacc accacccaga cattccattc
    44641 catcataaaa tacaactgct tgtccaggag tgattgcacg tacaggttcg tcgaatacga
    44701 cttctgcacg attatcatcc aataagcgaa ctgtcacagg aacgtcttgc tgacgataac
    44761 ggaatttcgc tgtacacttg aattcttttg gcattggttc attcgtcgta aagtggattt
    44821 cacttgcatc caagcttgtg gcatacaatg caggatgatg gaacccttgc cccacatata
    44881 atgtgtttgt cgctagatct tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc
    44941 caccgatccc tagtccttga cgttgaccaa tcgtataata tatcaagcca gcatgttgtc
    45001 ctttgacttc accatcaaga gtgaccatat ttcctttttt tgctggcaga tagttgctca
    45061 aaaattgttt gaagttcttt tcaccaataa agcagattcc cgttgaatct tttttcttag
    45121 cagtcgcaag gcctgcgcgt tcagcaattg cccgtacttc tgatttttcc atgccgccta
    45181 gagggaacat cgtttttgaa agctgttctt gtgataattg gctaaggaag taagtttgat
    45241 ctttattatt gtctactcca cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt
    45301 gcgcataatg tccagtagct acataatcgg cgccaagatc cattgcataa tccaagaatg
    45361 ctttgaattt gatttctttg ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt
    45421 attcggctag gaaatattca aatacacgat cccaatattc tttttcaaaa ttcacagagt
    45481 aataaggaat cccgatttga gcagctactt tcgctacatc cttataatct tccgtggccg
    45541 tgcatacacc gttttcgtcc gtgtcatccc aatttttcat gaatattccg atcacgtcgt
    45601 atccttgttc ctttaacaaa agtgctgtta cagatgagtc gacaccgccg ctcatcccta
    45661 cgacaacgcg tgttttgctg ttgtctgtca tgatatcacc atcatttcaa ttagattctg
    45721 aaacatctac gagttgaagg tcgcaacttt tcagtatttt acattatacg tcatatttct
    45781 gaaaatttca tcccttaatt atcaagtcgt aaaaatactg ttctactgga cctattcagt
    45841 acacaaacat gatagtcaac caaaaaatca ctcatctttt gagcattcga tataaaaaat
    45901 tggcatactc ataaaaaggg ccagcctttc ggcaataagg aataatttta taaattgtga
    45961 aaaactattt ttcaaaattg cttcttatcg cttaaagctg cacgtctcat ttacaacctt
    46021 ttctttttag atgttatgag ttgctcagat aagtgatttt gtttactcta agaaaaaagg
    46081 gaggcaaaag atacatgaat tactttatca gtgatatgca ctttttccat gaacgcttat
    46141 taggaaaaaa cgactttgct ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt
    46201 tgatcactag ctggaatgca gtaataaaag aaaccgacca tgtttatcat ctaggcgacc
    46261 ttgctatgca tccgcaatat gaaaaagcaa atgcagaaat tttggaactg gtcactcaac
    46321 tgcaaggaac aatccacttg atcaaaggga accatgacag tcgcgctttt ttccgttatt
    46381 tagaaaaaaa tgatcctagg cttactgacg gaagtcccaa attttatttt tatgatgtag
    46441 gtgccatcgt taaattcgac catcaacaat attacttgac tcattatccg atgttgctcg
    46501 ggcctaacga cactatccgc aatcttcatg gacatatcca tcattacagc gtacctatcg
    46561 agaacgatgt caatgtaggc gtagacgcac cggaaagaga actcttaaag gaaaaactac
    46621 catttggcac tccgttatct gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt
    46681 acgataggtc gtgaaaaaac tgccctatat caagtattaa acaaataaag ataattactc
    46741 atatttttca tttgagtagg cttattgcca caggaacatt aggatcagaa atggagttgt
    46801 aacaagactt ctgtcacaac tccattccat actattcgtc tttttgctca tggtgttctt
    46861 ttaccagttt tttctgtaat tctttatcat aatttcgggc agctgacgtt aaaaataaaa
    46921 cgattccgca taataaaatc ccgattccgg aaaacaagaa cattttttct acccctaaac
    46981 gatcagctaa tggtcctgca aataataatc caattggacc tgccaggttc atcaaagagt
    47041 tgaagttccc taagacacga cctaaaacat tcgattcata actctgctgg atcattgcca
    47101 tcagcagtgt attgaaatat ggcgttgcac aacctgctcc tgcattcaag ataagaaagt
    47161 acaagaaccc ttgactatcg tttggaacca atccgcttgc accgatcgtc aggcccataa
    47221 tgatgtaggc tataataata ggtttcattc ggtctttcca tgttcctata aaactgatca
    47281 gtgcaccgcc taagagcatt ccgactgcgt agactacttc cactgctccc gcctgtccaa
    47341 cggaaccacc aaagtaatct agcgtcatca atggatacag actgattgct ggcatgaaca
    47401 acagcatcac aaatgcacca ttgatcgtta tgtaccataa ccctttatta tccatcaatt
    47461 gctgcagccc aaattttgca tctttaaaaa tagtaagcgg aacttccaat atttcaggag
    47521 aaacttttgg gatcttcaca aaaatcaata agccgacacc aaaaactgcc cccaatacat
    47581 ctaataaaat aaggtaattg acaggaacga ctgaaaacaa agccgcacct agagctggcg
    47641 caatgatgaa attcgctgat tggaccattc ctaactgtcc attcgtcctt gttatgtgag
    47701 aagatggaac gattgtcggc ataatcgact ggatcgttgg catttggaat gtttgtgcga
    47761 ccgaacgcat aaacaaagac acaaaaacta gccaaatcgg gaaggattct gaaatcgttc
    47821 cgactactgc taaaataagc gcgaaaatcg ctacaataat atccgtgaca atcaaaagag
    47881 cttttttatc ccagcgatcc actagcggtc ctacaaatgg gcttagtaaa accatgggaa
    47941 tcattcctag taaagtagca aaactcaaaa ttgtcgccga accggtttct cttgtcaaat
    48001 accagatgat cgcatattgg acgaccatac tagtgattcc tgacaaaaac tgtcccgata
    48061 aaaagaacaa ataatttctc ttccaattcg ttaaaacgac cgactgttca ttttccataa
    48121 acatccctct tttctttttc attttgtata gtgtttgcac aacaatcatt atacgggatt
    48181 cttttttcaa aaaatacctt tttccctaaa taacaatcgt ttcaatttaa atttctttac
    48241 ttagaaacaa taaatcagca aaatattaaa aataacaaca tgtgttaaat ttaaaaataa
    48301 aaaagacaac taatttgcgt cgtccttaca aagttagtca tctaacaata ggccgtttca
    48361 aaactagttg tctttttata tccacagatc attcgacttt ttcgaataac ccacggctaa
    48421 tcatcccatc catcagaaaa taaaatttat cttggctcat tttctgtttt ggatctttga
    48481 aaatattgac tgctttcaat ccatttgctg tagtgatcga cattttcaat gtttgaatat
    48541 cttttgatac agtgattttt aatttgaatc cttctttgct ttgcggcgtg gcatctaatg
    48601 gtcggatcaa ttgataattg cctccgtttg tttctgtaaa tccattatcg cgcaatgtat
    48661 atctttttgc atcaggatgc aaacgatagc taattggtgc gcccagtacc gttgctgttg
    48721 tttcaaatgc catgattttc acctcgataa aattagtttc tctttattat aaaagtttat
    48781 cctgattttt actaggtttt tcagttaagt tccctaaaaa atgaaggcgt tctctcagac
    48841 atctgttcat ataagaatga cttcactagt tattttttga cagcacgaac taattgatca
    48901 aggaaatact ggatgtcgtc ttcggtattt cccaaaccaa agctgatacg gatggattct
    48961 tttagtatcg gtgtatcttc tccatacatt gcttctaata cgtgtgaagg ctcgatattt
    49021 cctgctgtac aagctgaacc agtagaaata gcgaccccat taagatcaag cttcatcagt
    49081 agcaaatcat ttgcttcgcc aattaagcga agattcaaca catgagggag tttattcgtt
    49141 aaatcaccat ttacttgata agggatttcg tttgcttcta atgtatcaag aatcaattgc
    49201 tggaatcctt tatatttgtt gttacgtgct tcacgttctt caggtgacag cagttcaact
    49261 gcttttgcca taccccagat ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc
    49321 tgctccccgc ctaaaagcaa tgcagggata tttactccgt ctcgtttata taagaaaccg
    49381 acgccttttg gcccattgat tttatgagca gagatactta ataaatcgat tcctaattct
    49441 tctggatgga tcgtttggtt tccgtacgct tgtaccgcat ctgtatggaa ataagctgga
    49501 tgatccgcta aaagttcacc gatttctttg attggcatca aatttccgat ttcattgttc
    49561 ccgtacatca cagagaccaa gatcgtatct tctcgtaacg cttttttgac ctcttcgatc
    49621 gacagattcc ctttttcatc tacaggcaga tatgtaacgt caaacccctt tgtctctaaa
    49681 tatttcatgg tattaagaac agcaggatgt tcgatagctg tagtgattag atgtctgcct
    49741 tctttttgac gcgagaacgc tgtttctaag atagctgtat tatccccttc tgttccccca
    49801 ctgttaaaga tgatctcgtg aggttttgct tgcagactgt ctgcaatgat ttgtcttgct
    49861 gtttccaatt tttcatgcgc gtggcgacca aatccatgta tgcttgaagg atttccaaac
    49921 gtgtcttgca tgattgccgt catcgcttca attacttgtg gatgcatggg ggtagttgcc
    49981 gcatgatcca gataaatagt tttcacttca ttcatccctt ccaaattatt gctaggcaca
    50041 ttctagcata aaatagcgaa caaaccaaag aagagctcat ttttgtctag aggacgtttc
    50101 atgggcatag aaaaaaggag ctgtgacaaa agtcttgtcg cagctccttg aagctgctca
    50161 cttctgtcac aacttctttc cctctttttt ttgtttattc gaattctttt tcttccagac
    50221 ggaataacgg actcatcggt gtattttcat ggatgcgttt gaccgcttca cccattaatt
    50281 ctgaacatgt aacgattgtt aagttttctg gatgacgatt ttcttctgtg aaaacagaat
    50341 cagtgataca aatatctttg attggtgcat tgtctaaaat acttttcgca tgatcggaca
    50401 ataatccatg tgacgcacag gcatatactt cttttgcgcc gttttctttt aatacatttg
    50461 ctgctcgtgc aagcgttgct cctgtgttca agatatcatc taccatgata catgtctttc
    50521 cttgaacatc accgatcaca taaccaccct cagttgaagc atcatctgca tgatctacga
    50581 tggctaatgt gctgttcaaa tattctgaaa gactacgtgc acgctgaaca ccgctgtttt
    50641 ttggcgaaac aactacgatg tcatctcccg tcagacctaa ttgacggtaa taatgagcaa
    50701 acaacggcat cgtaaataaa ttatctacag gaatatcaaa gaatccttgt acttgaaccg
    50761 tgtgcagatc taaagtcagt actcgagttg cccctgcttc ttcgatcaag ttagcgatca
    50821 atttcgcagt gatcggttca tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt
    50881 aaggcaatac gacattgatc gttttcgcac ttgctcgctt cattgcatcg atcatgatca
    50941 gtagttccat atagtaatca ttgacaggtg cattcgttga ttgaacgata tacacatgat
    51001 cccctcgaat actttcttcg atattgatgg aaatctcgcc atcactaaat tgcttcacga
    51061 cgcttttacc taattctgtt ccgaacactt tcgcgatttt ttcagctaat ggacggttgc
    51121 cattcaaact aaaaatcttc aacgtgtcat cctgatactt attactcatg tagtcctccc
    51181 caaaacttct ctattcttcg atagtttaac atatttttcc aagattttct gttaatttca
    51241 gcaaattctt aaggaagtga aactgttccg ttactccaac tggcaggaat gactttatga
    51301 taatcgcccc agttgtcgtg tactttgtaa taacgttctc ctgtttcagt ttcaaaataa
    51361 gcgtacgctg tcacccaatg attgccatat gtactgccaa gtactttcaa aataccaatc
    51421 atcacaggtt tgccttcacg tatacgtttt gtagctcgct gccatgaacc tagaagagtt
    51481 gctcgtgcac gctcatgatt gccattcttc tttaaaaaac tagaaatccc tgtactaacc
    51541 tgaaaaggaa tcgtaggaag tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa
    51601 accaacgaat cagccgtatt tttcttgcga atctcatttg gaagcatcca ccccttacga
    51661 tagtcttgat aataggcaag gagaactgct gccgcgtaag taccacaaag atagcctgag
    51721 ggggtagccc atttcttata cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt
    51781 gcgagttcct ttcctgacct tttttcttcg atcaaaacgg gaatatcttc ttttctgttg
    51841 atccatctag ataactcgat tggctcttca ttgatcagct tccatttttt acaagaaaga
    51901 ccctcttgat aagtatattt tgctggagaa tattctaccg gatgtcctga ttgatcgata
    51961 atcacataac tttgatcttc aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac
    52021 tgcagctgct gagtgctggc taatttttta atttttttat ctactttgaa atataaaggt
    52081 ttatccacta cttgattcag ttgggatcgc ctcctttttt tcattataag tgaaggattg
    52141 aaaaaaacaa atcagtttga ttgttcgaat tttcaatttt ttatgttcta tttgttaatt
    52201 ccttcatttt gtaagataat gggcacacga aacaaaaaag gagcgatcga tgaatgaaca
    52261 aagaacgatt gaaacaagat ttctatgaag cagtcaatga agaatggcaa aaaacagcaa
    52321 aaatccctgc agataaacca gctacaggcg gtttccaaga tttagttgac gggatcgacc
    52381 aacttttgat gggagaaaca gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa
    52441 aaatgaaaca tttccttgca tattatcaac tggcaaacga ttatgaccga agaaatgagt
    52501 tgcatgctca accgcttcaa cctataatcg aaaaagttga atcattgcag tctttcgacg
    52561 aattgaataa gcaatttcca gaatggctgt tggatacatt accattgcca tttaatctgg
    52621 atgtagatgc agatatgaag aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt
    52681 tattccttcc agataagacg tattatgcat cagaccatcc caacggtgca caactaatag
    52741 gcgttttctt tgatatggct gttcagttat tagagcttgc cggcaaagaa aaaagtcagg
    52801 cagaagcaat cacggaacaa gcagtgcaat ttgataaatt gattgctcct catgtaaaaa
    52861 gtgcagaaga aaacgcagat tacagcaaaa tgtataatcc gcaatctttt gatacattta
    52921 ttaaatacac agataaactg gacttgaaaa aacttgtcac gggtttgatt gggacaactc
    52981 cagataaagt gatcgtaact gatccagtgt acttcgatca tttgaatgac atcctgacag
    53041 aagctcattt tccgttattc aaaagctgga tgatcattaa aacagtacgt tctcttagtg
    53101 gttatctatc agaagaattc cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa
    53161 cagacgaagc aatgcctcag aaaaaagcag cgtattacct tgcctctgga caattcgatc
    53221 aagtagttgg cgattactac ggaaaaaaat attttggcga agctgctaaa aaagacgtag
    53281 aacaaatggt gaaaaaaatg atcgccgttt ataaaaaacg tctagaagaa aatgactggc
    53341 ttggggatgc aacaaaagaa aaagccgtca taaaattaaa taacttaggt atccaagtag
    53401 gctaccccga taagatccca gcattattcg accagttcaa aacagtacct gcagatcagg
    53461 gtggtacttt gctttcaaat actcttgttt tcagcaaact cacattaaaa gatcgtttca
    53521 gcaaatggaa caaaccagtg gatcgttcag aatgggaaat gagtgctgac acggtcaatg
    53581 cttattatca tccatttcgg aatgtgatcg tctttccggc agcgatcctt caagcaccat
    53641 tttacagtct agaacaatca agctctgcta attatggtgg aatcggagct gttatcgctc
    53701 atgagatttc ccatgcattt gataataacg gcgctttatt tgacgaatat ggcaacttga
    53761 acaactggtg gacagaagaa gatcttacac aatttcaaaa caaagcacaa gcaatgatcg
    53821 aagaattcga tggtctgcct tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg
    53881 aaaatattgc tgatgcaggc ggtctaagct gtgcattgga agcagcaaaa acggaatcag
    53941 atctttctat cgaggaattc tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa
    54001 aagaatacca acaactttta ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa
    54061 acgtgcaacc aaaaaacctt gacgaattct atgaaacatt tggtatcacg gaacaagacg
    54121 ctatgtatct agcgccagaa aaaagagtgc gaatctggta agaggttgtg ccagaagtgg
    54181 tcagcttcaa gaaataagaa ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt
    54241 cggcttattt ttcgaagaag ttacttctgg aataccatgt attagaggtt gtgaaaaagc
    54301 tgcttagttt caagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa
    54361 atttgactta ctaccgagaa actggctttt gaacaccgtt tatcgagagg ttgtgaaatc
    54421 agcgtcctga cctgagtatt agagaaaaaa acggaaaaat agttcctcat attttgccgt
    54481 ttgttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa
    54541 aagctgtcct gcatcaagta ataagaacag ccaatcaaaa gcagcaagga gaacctcatc
    54601 tataaaaaga tagaaggaag tgagacatct attggtctca tttccttcta tttttacttt
    54661 cctcagtcaa ttgttttaca tcataaaagg agaaattcca cttatttttt tcgctgtttc
    54721 atgacataaa caactacacc gattaacaaa attcctccag ctaatgctag caacgggtta
    54781 ttaaattctc ccgtttttgg gagtccttga gtgccatttt tttcactttc ttttgctgtc
    54841 ctatccggat gagaaggttt tccatttggt tttccatttg gtgattcatt tcctggattt
    54901 tctctttctg gtttgtcatt tcccgggggc acatcggcag tttctcgcac agtgatcgct
    54961 ttttgctggg taacagattc tgtatgagca gaccattttt ccccatcaaa tatttccgaa
    55021 cgataagtga cttctagcgt atattctcct tttgaaggtg ctgaaaaaat agcggtatga
    55081 ttagaaaatt gagcacttga ctgtgtttca acgatttgga tcttttctgg gaaataacgc
    55141 atatcttcaa agacaggcgt tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa
    55201 ggcttcagtt caatgatatt tccttctgca ttctccgcca caccatttgc ttcttgtata
    55261 ataatcggat tattttgttc atttggtttt gtctgatttg gttcttgtac gattgcatac
    55321 tctggatatt ccgaagacgg tgaggtttct ccgtcaaaaa tagcacctac agataatgga
    55381 agaccatcca ctctttcctt ttctgtttga cgattccccg gtttaatctg catcagtcca
    55441 tgaacatgga tacttccatt ttcatagcgc gtaacaggct gctgaccttc tttcgaacat
    55501 gtatttagag actcgatcca atcttttgat atggtatgtc caagagtatt ttctgattgt
    55561 ttctctcgtt cattccaata gtagttcaac gagtggtaga tttgatcttc gttttgattc
    55621 aatgggcgga tctgctctct catctcaaga ttctctgttc ggaaagataa gataccagaa
    55681 gcatggtagt ctgtgtttcc tgctgaagag gtataaagag ccacattata tgaaccgtta
    55741 ttaaaacttg tactgctatt gacgataata tctgttccgc tattggaatc gattcctttc
    55801 gcaagatttt cgaaagacaa actattgatc aattcatgag ggcccgttaa agaagaaccg
    55861 cccattttga atccattacc gttaccttct ccctcaattc ctggtaccca gccgtttcga
    55921 taagcaactg agtttttgat gattactttt ccgatcgaac ctgtttcatt tttagcaaaa
    55981 aggtcccaac cgtcatctgc attatgatac gcgatacaac cgtcaaatac atttccttct
    56041 cctattgtca gtttggccgc aaatccatcg gcatcttcaa atcctggatc ggcattttca
    56101 aaagatgtac agttcttgac taagttatgc gcgggccatg cttcgaaagg atcatttgag
    56161 ctaccgctga tttggattcc tgtatttcca ttccgataag catgaatctc ttcgatcaaa
    56221 ttatgatttc cagaaatctg taatcctttt tgcatagctg cactatttgt aatgtcaaac
    56281 cctcgtaaac cccagtagtg actgaacagt gtcatcccat ttccagttcc tttaaaatca
    56341 agtacaggac gcttgttttc tggatttttc tctgcaatca actgaatcgg gttttctctt
    56401 gtcccgttaa cgccttttgg aatcgtcaat cctctttcga aggaataagt tccaggcgcc
    56461 atgacgattg tctgcccagc atatgcgtat ctcaatgctt gtgtcagaga taatggattt
    56521 tgtctgcttc cgtttcctgc atctgaccct tctggtgtta cataaactgt cgaatattta
    56581 ggtttacggt agtccactgt atgaagaatc tcttttgttt cataactagt catctctacg
    56641 tattcttctg gcggatagtt tttatctggc gtaaaactga aagtaaattc gttcgttcct
    56701 tccatcagtt ttgtctgata atcaaattcc cgattcgcag tgatagccaa gttttttgcg
    56761 ttcttaagca cctctcctgt tgctttattt ttaattgtca ataatccgtc agcatttgct
    56821 ctaaaggaca tagtatgatc ttggtttcct gaatgattac tagaggtcac agtgtaaatc
    56881 ggatcaatca agcgagtagg tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa
    56941 gcaacttcga ttccttctac cttgatcgtc atattccttg ctgcagcaaa tcctgcataa
    57001 ataaccgatt catctgaagc gtataatttt tcccagtcat acatgatgtc agaagccatt
    57061 tcttctcctg tttcaggatc gtaataatat gcctctaaac cagtattcgt ttttttcatc
    57121 tctacgtcca gtttagtaat cgagttcgtg gccggaaaca gattcccatg accgtttccg
    57181 aatatattat aagaacctgt ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt
    57241 gtttccactg agacactccc aggagctggc gcagcttgcg gatcttcaga tgatattcct
    57301 gtgattgccc gtgtccccaa tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc
    57361 acttcttgtc tatccgagtc ccagacatat tcgatccgac tgcctagtat ggcaaatgaa
    57421 tttgaataaa atgcctgccc aaacaaatga ttttttggta ctgcgtctct taccattaaa
    57481 gcaaatcctt cttgggcatt cgtataggtc caagattcta tttcgatcgt cgcccgcatc
    57541 ctaaagttga tgtctttggg gattgcttga taataatagg tcattccatc tgatccgctt
    57601 gactggaatt ttccgccgtt attcgtggaa gagagccgca cgccgtcttc taatggttca
    57661 atggcatacc tactagcact tgtgctttct ccgaaaacaa cccctttcca ctcttcattt
    57721 gcttcttcag attgcttttt tgtcttttca ttttctgatt ctttcatcat aggatcattt
    57781 ccttcttccg tatccatatc ttcactagtt cttggtattt cctccattgt tgacatccct
    57841 tcaatgttca cgtgtgcatt ttcttcgttc acagactgtt gttcgttagc agcaacttca
    57901 acgacagaaa ttaaaaccgg ggtactgagc ataaggagat tcatcattag cgcactgtat
    57961 tttatacgtt tttttaacaa gtgtattcct cccgtaacaa attagaaagc gtttacttaa
    58021 agtattacct aatttatttt tactgtcaat aaaaaacaaa attataataa gtgtatttta
    58081 taaaaagaaa aaatataact taagttgttg ataataaaga gatttattaa cgtaaaaaga
    58141 ataagttttt ttaaaataac gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc
    58201 tcttctttta ttattttgtg ctttttattt tatcaaatca ctttgttttt ttataaaatt
    58261 tctgcgccta gtgtggactc aaaatgtctc aatgcccatt catgtccaac gggatcgaaa
    58321 cttgccacgg catctttgaa aatatggagt ttgtatccta gattatacgc atcgactgct
    58381 gtatgcaaca cacagatatc tgtacatacg ccggtcaaat aaatatctgt gatctggcgt
    58441 tctcgcaaac ggatgtctag atctgttcca ctaaaagcgg aataatgccg tttgtctatc
    58501 caataaacat tttcctcttg ctcatagtct tggtataaac tttttaaaga gccgtacaat
    58561 tcccgtccac ccgttcctat cacattatgc ggaggaaata agcggttctc cggatgaaag
    58621 gaatcttttg gatcatgcgc atcaatggca aaaacgacaa aatccttttg atcaataaac
    58681 ttctttgtat gagcagtcag ctttttttca attacttgtc ctgctgtccc agtagtcagc
    58741 tttccatcct ctgcaacaaa atcatatgtg tagtcaatcg agatcaatgc gttcatctta
    58801 gtcctcctta tacgagatgt ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg
    58861 cgtcttcgat aaattcgtca aagctttgtg tcgccgagtg atctgctgtg tcgctcattg
    58921 cacgtacgat caaaaatggg atattgaact gacgagctgt ttgtccaaca gcggctcctt
    58981 ccatttcgca agctaatgct tcagggaaat tcgttaagat ttctttgatt ttatctggcg
    59041 agtcgacaaa tgtatcacct gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt
    59101 ttgctgcttt aaccatttca ctgcgcaaat atgtgcttgc ttcataatat agaggcattc
    59161 ctggtaattg tcctgggttg tagccaaatc ctgttgcatc tgcatcaaaa taagctactt
    59221 tgtctgatat aacgatgtca cctacttgta agccttcacc gattccgcca gctgaacctg
    59281 tattgatcac catgttcacg ccgtattgtt ggatcaacag acttgtggta atagatgcta
    59341 agacttttcc tataccggaa cgtacgacga tcacttcgtg gttacctaat gaacctgaaa
    59401 taaataaagc gcctgcgcgt tcccatgata atggttcgct taggttctct ctcaaaattt
    59461 ttacttcttc ttccattgcg ccgataatac cgattttcat ctttttaatt ccttctttct
    59521 atataaatgc gattgctaaa aaaaccacac ataacattag gataacaata ataagagatt
    59581 tcatcaaaaa agagttccat ttggtcgtct tttcccgttc gctgatcctt gttttcgtga
    59641 ttggtttatt ctttttgctt tctttacgat aaaagctggc aatctttttt tcttcttgct
    59701 gataagctgt ttctgctttt cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc
    59761 gcttgcgaag ttcgcttcgc gtaataagcg gtcctttggc cataagccga tccctctact
    59821 ttcctttggt caatagttcc cagtattgaa tcgcataaat cgtctttgca tcacaaatca
    59881 actgatcttt catcgcttgt tgcgcctctt caagagttag atgatacaac tccagtactt
    59941 cgtcttcatc ttgtgctaaa ggattctcga ccttctctac cccttgtgca tgataaatat
    60001 gaaggacttc atttgcaaaa cctggtgaaa gatacatcga agtaagatgg ctcagcgact
    60061 tcgcacgata gccagtttct tcttctaatt ctctagctgc tgtcatttcg ggattttgtc
    60121 cttctcctgg atcgattttt ccagctggaa tctccaaaat cactttttct aaaggttttc
    60181 gaaattgttt gacaagaagc agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc
    60241 caggatgaaa taccagttct ctcttcgaag ttcctccatc tggcaaacga acttcgtcta
    60301 cagcaacatc aataattttt ccgctataga tttctttgcg actgattgtt ttttcttcaa
    60361 attgctcatt gttcagcata tcttctcctg ctttctttgt aatcataact gctttttttt
    60421 catttttcaa tttttctcaa aaactcctta ttagtttacc atagataaac cttagatttt
    60481 ctctaaatat agaaaatcct tctttagtcc gatactcttt atagtagtcc gtatgctaaa
    60541 ataagtatgt aatcgaataa cgaaaagaat tcaatactca acgataaatg acatggaggg
    60601 tttattatga taaaacgaaa ttggccgtgg cttctagcat tggtcttgct atttctcttt
    60661 gtccgaaaca atagtttttc ttttgttcta ggacttttat tgataggtgt agttttagtt
    60721 ttgtggggac tctttggttc gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg
    60781 actgacgaac ttgaaactca ctatgaaaaa agcggtatga cagcgaatga aatttcattt
    60841 tttcgacaaa caatgaatca aacaaaaaat gagatcaatc aattgcaaat gaatatgcag
    60901 cagacagcca aacttaaagc aatcgatctc cgccatgatc cagtcaaagc agcgaaagct
    60961 ttattcaaag aattggtgaa agaaccaaac cgactgcatg aagcaagtca gtttctttat
    61021 acgcatctgc cgaatctagt tgatttgaca aataagtata atgagatcaa tgaccatgag
    61081 atcaaaaaca aacagaccta tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg
    61141 tcagctttaa tcgcacaaga ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac
    61201 gtagagatat ctgttgcgaa acagagctta aagcgtgata ataaatatga accagaacaa
    61261 aaggattaac tcttttgttc ataaaagaag actcggaaca ttcagatgat gtctggctgt
    61321 ttcgagtact ttttctaaag tagagacatt catgtaagaa tcgagaacag attcaacaag
    61381 gaggaatttt ttatggatca taaaccgact gaaacaaaag atgttacacc agttaacgat
    61441 acacttgaag atttattgaa caacccgttt tcaactccaa cagatacgct gaccacttca
    61501 caacaagcgg agattgatca gctccaagag caacagacag ctgctcgttt aattgacaaa
    61561 ctaccggcgg aacgccaaga acaagctaaa cagctagcag caaaaatcga tgctaatgat
    61621 gcacagtctg tcatcagcta cggatcggct gcccaagcaa aattaagtga attctcacaa
    61681 tcgatgttga atcatgtgca agcacaagat attggtcctg taggagattc cttaactgaa
    61741 ctgatgtatc gtctccaaga agccaatcct gacgaactgc gtgccggaga agggaacatc
    61801 ttccagcgtg tcttcgggaa ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa
    61861 aagattggtg cacaaattga caagatttca gtgaaattag ataaagaaaa agacggtctg
    61921 ctaaaagata atctgatgtt agaacagctt taccagaaaa acaaagacta ctttgatgca
    61981 ctgaatattt atatcgctgc tggagaattg aaaatggaag aacttcaaac aacgatcatt
    62041 ccagaagcga tgaaaagagc agaagaaact ggcgatcaga tggatgttca gattgccaat
    62101 gattacacgc aattcctaga tcgtctggat aaacgtacgc atgatcttcg cttagctaga
    62161 cagatcacga tccagcaagc accacaaatc cgtttgatcc aaaacacaaa tcaggccttg
    62221 gctgaaaaga tccaagcatc tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg
    62281 atcgcattga ccttgcttcg tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa
    62341 acaacaaacg acttattgaa gaaaaattca gaaatgctga aaatctcagc catcgaaaca
    62401 gcgaaagaaa atgaacgtgg aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat
    62461 ttgatcgaaa caatccaaga gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt
    62521 catgcagaag tagagcttgg acacatggaa gaagatctga aacaaaaact gttggattta
    62581 acccaataga tcacctttcg cttgttacta aaacaaacgc ccaacaacag tttattacaa
    62641 ctgttgatgg gcgtttttct tatctttctt ctaacttctc cattggagtc tatttctcat
    62701 tcatcttgct gtgtccatag ccatagccaa aataaatgat cagtccaata accattacga
    62761 taccgaacac gatccatgtc acagtttgca gacgaagcat caatacaata caagtcaaga
    62821 tggagacgat tggcaatagc ggaacgaatg gcactttgaa ttctccagct tttggtttgc
    62881 caaacatttt tctcaacttc agtaagccta gactaacaag catcaaatag gcgagcgcca
    62941 tgatattcgt tagttccgct aatacattca atgggaaaaa tccggcaaag aatacagctg
    63001 ccacaccagc ggcataagtc gcttttttcg gtgtacgatg cttttgatcg atttctgtca
    63061 taaacttagg aagtaagcca tccttgctga cagcaaacag taaacgagca agtgaataca
    63121 tcatcgagat cgttaccgtc agtagcgtta aaattgcccc tacagcgatc accgcgccca
    63181 ctgttccatg tcctacatac ctcattgcaa aagccactgg gtcattgact cctagttcag
    63241 tatacggaac gattcctgtc aagatcagcg tcacgatgat gtaaaggaca gtagcaatca
    63301 gtatcgaacc aatgattcct cttggcacat ctttttgcgg gtttttgact tcctcggctg
    63361 ccattgcaac ggcatcaaat cccaagaaag caaaaaacac aagagctgca ccatctagca
    63421 caccggaaaa accaaaaggc atgaatggct gccagttatc aggtttaacg aaaaatattc
    63481 ctacaatgat aaacaacgcg atgataccaa atttgacata taccatggca ttattcaaac
    63541 gtaatgcttt cttggcttca agcgacacga tgtaagtgac gaatatcact acgagcaccg
    63601 caatcaagtc aatgtatgta ccattttccg gattgtaccc gccagttaat gcttgtggaa
    63661 gttcggcccc taaacttttc aaaaaacctt gcatatagcc agaccatccg gaagcaacag
    63721 aggaaaccgc tagtaaaaat tccccgatca acaaccaccc tgtcagccag gcagcaaatt
    63781 caccaaatac aacatacaga taggcatatg gcccaccaat cactggcact cgcgaagcaa
    63841 attctgcgaa acttagtcca gacaaaatga caacgattgc agctaagaca aatgaaagtg
    63901 acagtgctgg accagcattt tgattggccg caacccctgt caccacaaat attcccgtac
    63961 cgatgatcgc accaattcca agcatgatca aatcagacgt ttttagttct tttttcatct
    64021 cactcgtatg attgagattg atctctttct tacgaaacaa atccattgaa gttcctcccc
    64081 attttaggtt ggaaaacagc gattaaactg ttttcatata ccctaaaagg ataccaccta
    64141 aaatgactaa aaggcaacca acaataacat aaatgagctc ttttttcgtt tttctttcgc
    64201 caaggatgaa aatcccacct aaagtagaga taatgatccc catttgtgaa agtgagaagc
    64261 caacagctaa accaagtgat ttgactgtta gaagcatgca gatgtttcct aagccccata
    64321 ataatccaca gatcatgttt ttccacacaa actgatcgac tttaacttta cggaaagcaa
    64381 agaagcttgc gcctaagatc attccgatac tttgaggtaa gataattgac atcgcatcca
    64441 aattcgccca gttgacgatg atggtatata caccataacc aatcgtagag aagatcaatg
    64501 ctctaaaacc cttaccaaaa tcaagcattt tattatctgt atctattttt ccttcgtcat
    64561 cttgtcgggc agtcaaatac gcaccgctta caagaagagc taaagcaata ataccgtata
    64621 cataatcttt cgtttgtgtc cattcatgga agaaaacggc tcccgcaatc gtattcaaaa
    64681 ttaattgaaa accagtagac aatggtagcc ctacagaaac acccatgtac ttcattccat
    64741 ggaactgtcc attttgtcca acactccaag ctaagccgga taaaaatccg atcaagaaaa
    64801 tccaaggggt gattacagga ctaacaacga aaaagacaac taaagaaaac agaaatgcac
    64861 cgatcgtcat tcctagtgtt tgttgattgg catcgccacc aattttacca cttactaaac
    64921 caatactacc ccatgccaac atagggacta atgctattaa aatttccata accaatctcc
    64981 ttttatttca catgataaga aacttatcag cgaaaacgtt aacaacacaa gcactttttt
    65041 tcgtttctaa cgattttcta acgtttttca ttataaaaat ttaagattgg gaaaaataaa
    65101 gtcattgttg tcccttttcc ttcagttgat tcagccgtca aatggatacc taatttttcg
    65161 gccagatttt ttgctaaata aagtcctaat cctgttgaat gtgttttgct aagtcgacca
    65221 tttctcccag taaatccctt atcaaagatc cgtttcaagt cttccgctgg gataccgatc
    65281 cctgaatctt taactgaaag gctgactcct tgcgcttcct tttctatgct cacaatgatg
    65341 tttccgtgat ccggcgtata tttgatggca ttactaagca attggttgaa gataaaagcg
    65401 atccatttag catcggtcaa aacagtatga tcctcaccaa cgatctcgta gcgaatattt
    65461 ttttggataa aataatttgc ctgactgcgt atcacaggct gaatgattcc ttttagtcca
    65521 tattcttgga tgaggtagtc ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt
    65581 tctacgtatt catcgatttt tgataattca ttttctagta atgtatactt ttgatcgtca
    65641 atatcgaact cgatcgaacg aactagcaat ttagaagcgg aaagtggcac tttgatttca
    65701 tggacccatg agtcaatata atctttttgg tcttgttgat tactgattgc tgattgcatt
    65761 acttcttggt gttcacggat cagctgattg atatattctt ctaccagttt ttcttcttct
    65821 gtcctcccac cactcaaata attttgcaaa ggggaagttt tttgtatgtc ggctaatttt
    65881 ccccaccatc ttctcttgct caagtaacca cccagcagat aaaaaatcag aaagacgccc
    65941 tcaatcaaag ctaaataagc aattgtgctc aaatcaactt tgatgtttgg cgccagccac
    66001 atcacaaaga tcgtcaatgc aataaaaaac agccatccca agatcaatgt ccactgatct
    66061 ttcaaatatt taaaaaaatt catcttaacc gctcatcctt tcagggaacg atatatccct
    66121 gtcctacttt tgtttcgata tatccttgga tacctgcctg ttcgattttt cggcgtaacc
    66181 gattgatgtt gactgtcaat gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc
    66241 gcagcaattt ttcccgactt aagatctttc cattgtgctt catcaaaata aataatagac
    66301 gatattcatt tttgctcaaa tcaatgatct ctccgttgat ttccatactt ccgttgtcaa
    66361 cattcaacgt aatgccattg tggctcatca tttcactaga taattctgtg tagttgtaag
    66421 aacggcgaag taatgcattg atttttgcaa tcagtacatc gatttggaaa tgttttgtca
    66481 caaaatcatc tgcccccatg ttcatagcca tgatcatatc catattcgta ttcctgctgg
    66541 agataaaaat gatcggtact ttcgatactt cacgtatttt ttgacaccaa taatagccat
    66601 ccaaaacggg aagattaata tctagtaata caagctgtgg ttcttctctt tcaaagtctg
    66661 agaacacttg attgaaatcg gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct
    66721 ccatgaccaa ttgtcgaatg atctcttcgt cttcgactac catgattttt gccataaaaa
    66781 atccctccat ctttcttctt gctactacaa tatcaaagaa gcccttgtga aacaagttgg
    66841 cttacctgga aaatgtcatt ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat
    66901 cgcgtttgtc tcttccaagc agcttaaatt tattatgtta ttcttaataa ttggtctatt
    66961 atctgttatt tttctttcgt tgtttttgtc ttttaaattt tcgataacac caataaccga
    67021 aaagcgttag cactagcaat atacctagaa ggagtataag taatcgataa agatggtatt
    67081 tttttgtctg ttctatcttt gaagagactt cttctgtaaa gggaactcgt cttcctgtca
    67141 ctagtaatcg gtgagtgttc acggtgtaag gtgtacaagt gataagtgtg actagatcct
    67201 gcttttctct aattgctaat gtatttgttt ttgttggaag gacaacaatt ttctcaacga
    67261 cttcataagc gagcatccga ccatacactt caagatagaa tcggtcatct tgctccattt
    67321 cttcaagatc cgtaaagagt tttttctcag caataccgct atgggcggta atcacggaat
    67381 gtgtactctc tcctccagtt ggaaaagagg tgccttgcag gactgtcgct cctctatcta
    67441 acaaaagatc attcgtttca tcaaataaag gcaagctaac attgattttc ggaatataga
    67501 tggctccgat catatgttgt tcgtaatatt cttttcctgg attttggaca tttctaaccg
    67561 cttgctcaaa aggatctttg acttgtccca ttcctgggat tactgatgta tgagcaagcg
    67621 tctgattttt cttttcatgc actgctaatt gttgctcatg tttttcttct ttatcgcgtt
    67681 caagctgctt ttgataattc tcgatccttc tttgatccaa ataattgctg agagcatctg
    67741 ctaaaaatgg atatgtaaaa actgcagctc cggcaagaaa catcactgcc ataaataatt
    67801 gtaataaaag actgatttgg gtttgaggtc tattacctat tttctttttc attttcttca
    67861 ccttcttatt taaaaaaact gcagcaacct ttataaaacc gattgctgca gcttattttt
    67921 gttgcttata cttcagactt cattttagat ttacggtacc agctgtacgc tccaatcatc
    67981 aaacttattc cgattagtaa gaatgccaag agcccgttcc caccagtagc aggaagtgac
    68041 ccgcgtttca tattcggtac tctttctggc cctggatttt ctactcctac gatctgaatt
    68101 tcttcattat agcttccata agagatgata aattcagtaa aggctgcctc acctgttgga
    68161 agtacataac cttctggcgc catggtctct ttcatttgat aggttccata atctaaccct
    68221 tgaacctcaa agtatccatt tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc
    68281 cactcaattc tatctgctcc tgattcataa acagctaaag gcgactcccc tttataaaat
    68341 attgcgtatt cagaacggtc ttcattccac aattcgaatc ttgcatcttt aagcaattca
    68401 ctgcttgatg catcatattt ttcaaacttt cttccacctg ttgtgacttt ctctggcggc
    68461 tctactcctt cttcataatc aaattcatca tttcgtccga tttcaataac cgctgtgttg
    68521 ttatggaaat catccgcttc tagttctgtg gaaaccttca aattatacgt gatcgttaaa
    68581 tctcctccac gtgcatctgc taatctacct aaagtatcta ctttggctac tccattttct
    68641 tctgtcaaaa tcgtcacgac aaacccgttg cttactactt ctactatata atcttgtcct
    68701 tttgttaaaa tcgtctcgcc ggctcgcact tctatttcct gatcataata agttagacca
    68761 actgtaggcg tatctgtgat tttgtaattt ttgataacag cgcttccgtt ttcaaggaca
    68821 gaatcgatga aataaggaat aggtgctgtg atcgtgtaag aagccgtttt tcctctttct
    68881 agatcaatat aagaaatcgt ttcttgttct ccagcttcat taataatcgt tacttgtcta
    68941 aggtcgcttt cctctacatt catctgttta tctgcttctc tgatttcgtt tttcggatac
    69001 aaatgcacat ctgtattgta tgtgtctttc catgtagaac catcccacac gccatccacc
    69061 atatcaggca tcatcactgg catcataaca accattggag acgcgattct ggaaatatga
    69121 gctggcgaat aagtttctaa gaaaagatag actttatctc tagaagaagg tgcttcttcc
    69181 gtcacttgga cggtagagaa taccgcttct ccagcttcat tcgttgtttg tttgtcaata
    69241 cttgtcagtc gatattttaa aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc
    69301 gcttcggcag aattaagacc gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa
    69361 tcgtaatata cttccgttac gtcaaacaaa tcaaaatcga ctcctggaat attttcttca
    69421 ccaaaatccg tagaaaccaa tccgctattc ggtcgttctt ccggaacaga tgagaaacct
    69481 tttttgtgta atgtaatcgt cacttcactt ggtttttgtg cgacttcttc ggctttgact
    69541 agttttccgt tcccgaaaat ccctattccc gcagtaacga gtaacagtac actcattccc
    69601 gtgacaatca tttttttatt catttttttc tccccgttct ttttttatta ataaaacagc
    69661 acctaacaat aaaagaattc ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg
    69721 gaatacggac cattttcctg attgacctgg attgcttgga ccactcggct ctttcggttt
    69781 gtccgttgtt tcttttacgg tctcgttata aacacgtggt gttgcggatt cataggcaga
    69841 gactggaact ttcccggatt ctaattcagc catctcctgt ccgttaacta ctacatattg
    69901 tggttggcct tttgcatcca cccaaaattc agggatgatg acctcgattc tcttacttgc
    69961 ttcatccatc tcgtaacctt ccacaccttt taattcttca aaataatagg tgccagaagg
    70021 caagaaacgt tgtcctgtcg taacaaggcc ctctttatcc gaaatgaatt tgcttacatt
    70081 tttgtcattc aaaggatcat tgtctgctgg tttgatccat tgatttttca agtcattagc
    70141 aggagccata tctaaataat atttcccccc ttctatcatc tgatatagag caaaaacagc
    70201 accttctaat ggttttcctt tttcagttgt tcctctttga cgtccatact tgaagaagta
    70261 tggatctctt agataaccga catttttagg atagatatga atctcttgca gttcctcggt
    70321 tgattctgtc gggtgataaa ttggcaaaat agcagcaatt gggatagctg tctgatcgat
    70381 atcaacatcc aatccaactt ctggatcaat cgattcttcg aaaatcaaat aaactgcatc
    70441 ccgatcttgg tttttcttag gtgctttgat acgtgcaatc ccgtctccta atccgccaac
    70501 cgtatctttc ccagttgtta ccgaagtccc tatttggaca agcctttctt ctgtgattag
    70561 ctgacggata ttgtttctgt tcgtttcagc gatttgctgg acgaattctt taggagtcat
    70621 gttttcagca gctttttttt catgataata atcggtcatg tcgtaaatgg caaatgtcgc
    70681 tccatttagt ggcaccgtct gtgaaatgat atctgctgtt tcccctgctt cctcagagat
    70741 agccaagcca tcattttcat ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat
    70801 ccgtttatgc aacacgaatt ccacgacatc ttcccctgat tcttctgccg acatcgcatg
    70861 tggaagaagg actgctgcaa gcggtagtaa aacaagtaat tgaagcatca aacacaacag
    70921 ctttttcatt accttgctcc ctccttttta gattgtctga caaacaaacc ataggctgct
    70981 cctgcaagcg ccatgaagaa tgcagcaagc aggatataga ataatcgtcc ggatcctcct
    71041 gtagcaggca acggattttc aggatcgttc ccgacactaa gctgtaatct gattcgattt
    71101 gtctccaaaa gttcatattc taactcttgc tgtagatcag gcgtctctgc ttcttcgttt
    71161 ggataatacg aaatctcaac ttttagtgta cccgcttctt ttcctggaac tacccgatca
    71221 ttttctatgt caggttcttc tcgataacta atttctaaaa taaagtaacc tggaagtttt
    71281 ctatagctgt caggtgactt cacttccttg atccgataga ccccttccaa caagtctgaa
    71341 gcattgaata gggaagaatc gtttggatct ggtgccaagc ctccctcgat gatttcatac
    71401 tctcctgcac tattttgttt ctcaattgaa aattctgcgc cttcaagacg tcggctattc
    71461 atactgtcaa ttttcaaaag ttccaaatcg attggcgcta gttcatcttc taaggttact
    71521 tgtagtacac catcgatgat ttcatagcct tccggcaagg gagcagtttc gtcttcgatg
    71581 accgtatctt caatgataaa cttaccttct tcattcagtg caaactggaa cacttgatca
    71641 gatagccgat acccatttgg tgcgacagat tccgagacct catattcacc aatagacaga
    71701 tgcagaggtt ggtcgtaatt taaatcgaca tacttttcta ctcctacggc acgagaatag
    71761 aagtatccga tcccaggcaa acgtttcgat tcttctggtt ctaacggatt accagtgtat
    71821 gctcgataca gcgggaagga agaatccccc actttcctga tatcgaaacc tgcaccatct
    71881 aatgtatggc cttcatggtc taattttcta actcggatct cccgataatc aaacgtattg
    71941 taagcagtga atgctaccca taaacgatcc tcttcatctg ttgtatacgt gagatattgc
    72001 caattttctt cacctgtttg cttgagttgg atagtcccta tagcattatc gtaaagtcgc
    72061 aagatccatg tgtcattttc atcaggttct ttgaaacctt ctgggttctg gctctcaatg
    72121 attttgtatt ctgcatagtt ggtagtttct tcactatcct tataaacaaa tgaatctggc
    72181 tctccgattg gatgaataac tttctcacca tccacgatta catatttccc gtcttcatct
    72241 actgaataga acgtgagtct ccctttctct tcctctactt cgttcacacc agaaagccct
    72301 ttcgctactg gatatccgat ttccagtccg ttaccatctg tttcataaag ttcaaactct
    72361 gcgccattga ttggcatatt actgccttca attagtttat tgatattcat gtggattggc
    72421 ttgaattcat ttcgcatttc cagtttgaca tacaactcat catactctgt gccttctatg
    72481 ttaggctctt gtacaacaga aagcttgtga tattctcctt cataatagga attcggatct
    72541 ttaccttccg gtccgccgac tctcgaacca gatgtatatt catctacaag ctcgtagtga
    72601 cctaacatct catcttcgtt ggctgcatat tttttgattt ggaattgata cgtctcatct
    72661 actaactgat aacgtggtgg tccagcgatc tctctgatcc aaaatatgtc gctgactgct
    72721 ccagtttcat ctcctaaaat cggcatcttc gtttcaaaga tcgctattcc gtccgtggta
    72781 gttttacttg tttcgattgg ttcggcttcc ccactctctg gattttggtc atataatgca
    72841 aattcgactc cagccaacgg ctcgccattt tgacccttct tgctgacttg gaaattacgg
    72901 cctttatgtt cgtaacgaat ggaagaagat gggaaataca tccgtccagt agtgatatca
    72961 ttctcataat cctccaggtt ctgaatatag gccatattgt tcactgtgca aaaatttccg
    73021 tcttgagctc ccgcatcaag ttttacttgg tacttgatcc tgaccatttc cccttcacct
    73081 aaagaaatcg gagaaaattt ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc
    73141 gccactactt ctggtggggc ttgtccatga cgttcttcat cccatatttc tggctcttgg
    73201 tacttcatgc cgttttctcc tggatctaga tggtaaaact gaatatctgc cgatctgcca
    73261 gctccaaatg gtgagacatt aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt
    73321 ctcttgaagg tagaagagat atcctccaag gctgtaacaa tgtcattctt gttgttcgca
    73381 ttgtaatatc gcggtgttac gccatcttct tctaaatcag caatattttt caatacattt
    73441 cgtccaatag catctagtcg ttgtctcccg ctaacgtttc catcgattcc taaaccaatg
    73501 gagaagatac ttggcgggtt ctcttgatac ttgtttttca gccaatgatg ataagcaact
    73561 gtgttgatcg cagatgactt ttcttgcgaa gtaggactgc cattcgtatt gttattagaa
    73621 gaaccatcac caacccagtg agtcgcttta ttatctcctt cttttacctc tccataacga
    73681 tagtgtacat ttacttcatc ttctggacgg ttaaagtcag atgcataggt aactggatga
    73741 gtaaaccctg cattagaagt attcccagaa aactcctcaa aatttctgaa caaaacgtca
    73801 ttatcttcag caatcttatc ttccatcaca gtccagttgc tccaagctcc attagtgctc
    73861 gtacgataac ttgactgaat cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg
    73921 attaggattt tttctggatt tctattttct ccgccattgt ctttatacaa tgtttcatag
    73981 ccatttttaa gccctagtgt aagcggagtt cctccgattg gtgtacgatt taatgctgta
    74041 ttctcacttc ccgtcaaacg attgatatca tttgtcaatg gaaagatgtc cgaactgatt
    74101 tgctcatggt tattgatagc tgtactatta tggtaaaaat tcaccatacc gattcgaata
    74161 tccagactcg ggtcagagag cagatcttta ctcatttcgt ttactgcctc aatcaacgca
    74221 gcatttttag tttgactatt ggtcccagcg gttaattcac tcatactcgc tgacttatct
    74281 agaacaaaaa cgatatcgat tggactgatt tcctttttct cgcccccgat gacatctaga
    74341 tagacattgt aaagggttgt tgcatcttca ggatgtagat cagatgctgt gctgcttggc
    74401 agaacaggtt ctacccattt tttgatgtac gccccgttat aatccaagta actgttttca
    74461 aaattccgtt catttcccca aagctgaacg gtttgagctg gaacgtttct atcttcttcg
    74521 cctgcagttg atccattatt agtagcatag tcgtaatttc gccagttcgc tcccccgttt
    74581 gtataatcac tatcatcgat caagttctct ccgtcatatg gcgagccttt gtctccttga
    74641 tagcgttcat tgctttgtgt ccaatttcct aacacttttg tatagtcatt cgttgtaaac
    74701 ttcatctatt ctttcatcaa ccaccacttg aagaggtagt tacccttcgt tcacatcggg
    74761 gatcttttct gtttcaaaaa tcaatgtgcc ggtttctgct tcttttgaat aaacttttcc
    74821 gacataccat tcttgaccat cgatcgtctc gacttttagg tcttctccat cttcatcata
    74881 ggaggataga cctgttccac gaacgttttt tacggtacca atcccggcgg ctgccgcatc
    74941 gattgctaaa cgtattctac cttcattggc actttccttt ttttcaaaag ccagatgcca
    75001 ttcaagggtt tcttcttttt caatatactt cccttcaatt tttgcatagt cctcatctaa
    75061 gaatacctca tcctcctttg tttctgttga ctcagcagct acatccaggg tcgtcatatg
    75121 atagactgac tggaaatatg gtccaaatag caaactgaca gttactaact gcaaaagctt
    75181 caattttaac cctttcacat ccttatactc ctttcaaaaa tatttgtctt ctttcacaac
    75241 aatcaacaaa acaatgccca tctaattata atttaattta attttaattt taaatcaaat
    75301 gatatccttt ttagttaaaa acaccaatta tacaacattt attattaaaa ttaaattata
    75361 aaattttata acgttctcat ttaacaaaac ttaagttatt aagacaaatg aataaacaac
    75421 tacgctttcc tcgaaacaaa aaaataaagc acaaatgcgc atttacgcac tcatgcttta
    75481 ttcgtacaat taattcagat aacggcagcg cataggatgc caataacact tcctaaaata
    75541 gctcctccta aaatgtcagt aggataatgt aaaagtaaaa aaatcctcga ataagcgatc
    75601 aaacaagcaa ataaaaaggc taatattcct gcaactggac ttaattcgaa caacgcagct
    75661 actgataaaa aggctagcgc tgtatgtcct gaaggaaaag aagaagtctt cggtttactt
    75721 gtgtaaagga caagccgacg atttttttca taaggtcttt tccgtcttgt cgtttttttg
    75781 ataaaaagca aaccaacaaa aaaatagatc aaactgccga taagaatggc tagaccatat
    75841 tctctagtat caggtatcaa gactaaaaca gcagcaagga gcaaccaaat aaaaccacca
    75901 ttagagatat tactgataaa tttcaaaaaa ttgatttttc gactatccgt tttccgttgc
    75961 ttggcgaact tgttgataat actatcatcg attttagcaa tcaaacgcaa catgttattc
    76021 ctccttttta agaacctttt cttgcgtacg atggataaaa agcaggactt gaaaataaaa
    76081 caagaaactg aaacctaata aagcaaaata gattggtcct gcaaaccaga atgcgacaag
    76141 aaggatcaac gtgcctgcca aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa
    76201 aaatgcagta atccaagaag cttctttttg ttccagttga agcaagattt tgtaactaaa
    76261 gagaagcgcg cttaatagaa gcaaaaacaa cgtagtatac atcaatgtat agccaattcc
    76321 cccaccccaa tagcggaaaa tctgataatc gatcaataga agaagaaaat aaacacttgc
    76381 taaactatct tgctttccat aaagagagaa gttctcacga aactttttcc agaatagtga
    76441 accgagcttt ttctcttcat tttttttgta atgataaatc atatacagaa ctgttcgact
    76501 tgcagttcct aatgtgaaaa caggcaagac gcacaggaac catagtagct gtaaatggat
    76561 aagacgtgga atccattcaa tgatttctaa gaaataatca ttggcttttt taccaatcga
    76621 tcgattcatc atccttttga acctcctgtc aaatccatcc cttcaatgaa ataacgttgt
    76681 gcaaaaaaga acagcaaaat cgtcgggatc aagacaagtg ttgctcctgc catcagataa
    76741 ttccattgtg tcgttgcttg gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt
    76801 tcttgatctt ggatatataa cagaggacct aagaaatcat tccaagctgc gttgaaggaa
    76861 ttgatcgcaa tggtaatcaa ggcaggtttc gtcaatggaa gcatcaaatg actccaaata
    76921 tacaaatgat tcgctccgtc gatttcagca gcttcgatca attcattatt gatcgataag
    76981 taaaattgac gcatcagaaa tatattgaac gcattgccga agaacgatgg aacgatcagg
    77041 ggcaaataag tacctaccca gccgatcttg gagaataata catattgagg gatcatcgtt
    77101 acaaaccccg ggatcatcat cgtagaaaga accaaagcaa acatcagctt tttcccagga
    77161 aaatcaagct tcgcaaatcc ataagcaata aaagaatttg aaaggacatt accgatcact
    77221 actagcacag tgatgaataa tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc
    77281 gtatccagat agttttccca tacgattttt tctgggaaaa aggtcggagg ataacgaacg
    77341 atttcttcca ttggtttcaa tgaagtaaac accatccaaa gcaatggaat gatcaaaatg
    77401 attcctatta ctgtcatgag gacataactt agtatttttt ttgtttgccg attcacactg
    77461 gtctttttga aataatccat catttgccgt cacctccaga ataatagacc cacttaggtg
    77521 caagcttcaa attgacaaac gtcagaacca acacgatcag aaacaggatc attgacatag
    77581 ccatcgcata acccatatca aaagctacga acgccttgtt ccacatatgc agattataaa
    77641 aaagcaaaga atttgcaggt ccgcctgttc catttttcgt catgacataa gcttcttgaa
    77701 aaatttggaa agaaccgatc gtagaggtga tcacatcgta aaaaataata ggagtgatta
    77761 atggcaaagt aatacttttg aactttcccc aaacgcctgc tccatcgatt tctgctgatt
    77821 catataaaga tctaggaaca ttttgtaatg tagctaagta aagtagcatt gctcctccag
    77881 aactccatat tttcatcaaa atcaacgcag gtttcgtcca ttgtggatca aacagccaag
    77941 ctggtccagg gatatggaac cagcccagaa atgtgttgat caatcctgca gatggagaaa
    78001 gcagctgcat ccataagatg tagactgcta ctcctgataa gactgccggt aaatagaaag
    78061 ctgtacggaa tacactgatt cctttgattt tttgattgag tactgtggct aaaaacacac
    78121 tgaaaatcgt cgtcagcggt acattgaaga tgacgaaata aacggtgttg tataacgatt
    78181 tccaaaataa atcatcgtga acgaacattc ttttgaaatt tgctagacca atgaaattca
    78241 tcttggatgt caaattataa tcggtgaaac taccaataac tgaaaaaagc ataggcccta
    78301 gcataaatac caagaacccg ataataaaag gcgagataaa taaataggcc catcttgctt
    78361 cttttttctt tcggatagat aaacgcttca aattttcttg cctcctctgt acctagacag
    78421 tcaaaaatgg attattgatt ttgcttgact aagttttcta ctgctttttg tgcatctgcc
    78481 aatccttctt ttggtgattt tgttcctaaa agaatctggt caatctgttc attcactaat
    78541 gtcgtgtaat ccggagcatc taaaggaact ggtgtgatca ccgtattttt aaagttttcg
    78601 tccgccattt gatagatcat ttttccttta tccgttaggt tgtcattatt cactaaattc
    78661 tcattggctg tcttgctcgc catgatatca aaactttttt cgccgaattt ttcttgtact
    78721 tctggagaag aaagatattt gatgaattca taagaggcct caggatcttt tgctccgtat
    78781 ggtacttcca agacgaatcc gccaccccac gaccaatggc ctgaaccttc ttctttttct
    78841 gggagctgca tcacgccaaa atcaaaatca tccggtgcat tttccatcaa actagagtaa
    78901 taattgatat tttgggcacg catggctact aatccggaaa taaatggatc agatacacca
    78961 gacccaaatt cggcttctaa tttattgatc gtatttttcc cataataatc ttgccagtct
    79021 tggatccact ccaaggcttc cactttattt ttagtatcaa tcttgacttt ttcatctttg
    79081 tcaaaccaac tagtcccgtt atctgcgttt agcgcccata catcagcccc taaattccat
    79141 aatggataaa aaccgatgcg tgtaaattct tttccttctt ttttatctag tttacgtgct
    79201 gtttcttcta attcatccca agttgtcggt agatcttgtt cactgattcc agcttcttta
    79261 aataactttt tattataaaa aatgacttgt gtatctgtat tgaatgggat cgcataagga
    79321 tcaccttcat attctactgt atcccaaagc tgcggataaa aatccttaga agtgtctttt
    79381 tctacatatt tggagagatt agttgcttgc tgtgcttctg ctctttgggc aacggaattt
    79441 atgtcctgta caataacatc gggtgcattt ccagctgtta ttgcagataa agatttagtc
    79501 cagatgtcac cccatggctg atacttataa tttacatgga tctcgttttg tgattgattg
    79561 aaatcctcaa tgatttcttc gatagcttct tttcgtgcac cggatcccca aaaggaccag
    79621 aaatcaatat tttttcttcc atcacttgtt ttttcagaag aatttgctgc acttgaactg
    79681 gcatcgcttg cattacttga tccgcatcct cctaataaaa acaatgctga acttgccagc
    79741 aaccctgtaa acaataattt tttcatattt tacctccaaa ttttaatgta accgatgccg
    79801 gttttaatat aacgatatca ttttgttctg aaaataacaa tttataaggt atgattctaa
    79861 aaaaattatt aatgatacca atactttata taattcgcga gcgctttctt tgaatttttt
    79921 aatctttcgt agcagaatga gaatgtatta aaaatagatt aggaggaatt ttgatgttta
    79981 gacaccagaa agaattgcag tttgaagcaa aaccagatcg tccgaatcca ttaatcgcga
    80041 aatatctgca ggagctgatc ggcggccaat atggcgagat gagtgtagct atgcagtacc
    80101 tgttccaagg ctggagctgc cgaggagaag aaaaatataa agatatgctg atggacattg
    80161 caacagaaga aatcggccac gtggaaatgt tggcgacaat ggttgctcgt ttattagagg
    80221 gtgcgcctgt tgaagatcaa gaagcagcga tgcaaaaaga tccaacaatc ggtgccatta
    80281 tctctggaat gaatccacag cacgcgatcg tagctggctt aggacctcgt cctgctgaca
    80341 gcgtgggcaa tccatggagc ggtgcctata tcattgcgag tggcaacttg ttagcagact
    80401 ttagagctaa tttaaatgcc gaatcacaag gaagacttca agtagcacgt atttacgaaa
    80461 tgatcgatga tcgtggcgta aaagatatgc tgtctgttct ccttgcaaga gatagctatc
    80521 atcaaaatct atgggaatgt gcagtgaaag aattagaaga aaaagaaggt tcaatcttag
    80581 tcccaagtac tttcccgcgt gacaaagaac gaaaagacat tgcttatgac ttctataact
    80641 tctcagaggg agaccaaagt agtgaaggtt cttgggctag tggcaaagca ctggatggcg
    80701 aaggcgaata tcaatggttg aaagaaccta agatcgaagg cgctgcacca aaattagaac
    80761 cagtaacacc aaaaatgtat gggacacctc cattcaagaa ataaatatct acccgtagaa
    80821 acacccgttt tttgttccac acgctttgtg agcaaaactg actaaagtca ttaatcataa
    80881 ccacccttca aaagggtggt tttctctaga gctataagct caaatcaccg gccagcgcct
    80941 aaagacgctg gctttcatat tttatgttca agccatattg cctttgccag ttttgcccac
    81001 ctcttaaaag gtttatgtac tactccttag cccttaaaag gatcgtctta ctctcgtaca
    81061 ctcagcttat ctaacgcact atcatgtttt tcttgttctt gaatgtactt tttgatggtc
    81121 gcttcatttt gtcctacttt tgtcacatag tatccttcca cccaaaagtg tcgataccca
    81181 aatttatatt ttagatttgc acaatctctt gatgatctcc tgaatattgg ctcgatattg
    81241 attataaatt atttttcttc tatactttgg tgtgaataca atgtggtatt tacacatcta
    81301 ctttgtacgg gctaaactat ttccctttat tgctccaccc gcatagcaag tggttttgta
    81361 tttcaatcgc tcggcgcgct caattaggtc taaagacaat aaatctaaaa acccgctgct
    81421 tcactgacag aaacaacggg ttttcagaaa aaaatgaaat gaaaaagatc tcttacggca
    81481 atctatttta tttttttgat tttttataaa tggaaaatgc ttcaagaagt ccaagaaata
    81541 aagccgtata aaaacaagaa cctatgaaat ctttatttat tagatattca acagaaatcc
    81601 cgataacact agccaacaat atatttatca gaagtgtaaa ataaggatgc tttttataga
    81661 atagaactag tgttgttttc atagactctc ctttcttcat atttccaatt aatcacaaat
    81721 tcacggcatt actagaaaaa ttaaaggggc gcagaagtgg aaaaatactc ttcgactttc
    81781 cctacaaacc aggccatctt gtgtttaata actataccaa atctaaggta cctctaaatc
    81841 taaattccat ttgtggcggt gacctccaat ttttaactct tctatctccc atccagtata
    81901 cataaccttg atacttcgac cacttatata tcgaacacac aaatacctat ccattgcagg
    81961 agtactacct aacttagttg ctacttgcat ctaaataaca gctgaaaaga taggacttac
    82021 tcttagtaaa gtatctgaac tattaatttt taaactatca tttttatcct caactacatg
    82081 cacatctgtt gcaacttcac tttctgtctc atccagataa atgattaagg aatcgggaat
    82141 tgcaatatct tcagctgacg ctggaatagt tgagctaaat tagtcatcat atctttatta
    82201 taaaataacc aacagcaaaa aatacaatga aaaacaaact tggaactaat gtatcattaa
    82261 taaatgttga aaaattcagc aactcattac tgtatgattt tagcagccca accaacatat
    82321 accctataaa agctaataag atggttagga atcctttaga atttttactc attcatagac
    82381 acttccttaa ataactttta ttatagaagg tattgtaaat aataatattg acaaaaagtg
    82441 actcaaaata aaaaaaaact tacattatac tggaatgaac tgtattgata gtgtacctaa
    82501 aagctctact gacataagat cgtgtaatcg gtaaagtaat tttattaatt atacgggatg
    82561 taatcaatta gagaataaac taatcataaa aggtactttt acattcataa ttgtcgcttt
    82621 gagattctac tttggttcac tatctgaccc aattgcacat tttcgatcat tacaagtatt
    82681 ggtgtcgtta gaacaactaa ataaaaacta gcggtagatt tttcagaatc tatgctaatt
    82741 tctgtatgga tgttccagtg atggcaaatt tctcttttca ttgtttttct tgtcgcatga
    82801 tatgcctttt tgtgttattc agttaaacta tagaaattct ttcctagaca gatcttgatc
    82861 ccaaatttta cgtttttgag catcgatata gtttaaaatg acattactca tatctaaaga
    82921 gtttagattt tttaggacta aaactgtcag ttgttctttt tcttctttct gttaaagtat
    82981 tgtcgcgact tttcgtatac gttaagatat gtcgtgaaaa aacaagtttt gtgacacaaa
    83041 aaaacgaatg acttgaggaa atcacctcaa tcattcgttt aaaatgctat atattcttta
    83101 gtttaagata cggaaattaa tgccatcgac cacactagta gaatgaacga catttacttg
    83161 gccttttttt aatttcgtta tgtttagcat ataaaaatat tatagagttt acttacaatg
    83221 cttaaaacat atactgtata atctgatcaa ttttagccat gtcttgcaat ggtaagtttt
    83281 ctattttttt gagttttcgt tccttaaaat caagagattt taattgtgta ataattactt
    83341 gtccttttat atctagctct tcaggtaatg agtaacgtgt cggtaaattc tttatagtgg
    83401 aagtaattgg acatatgacc gaaaacattg ttttacggtt aaattcataa cgagagacga
    83461 ctagtcctgg tcgtcttttt tgaatttctt ttcctacgga gggatcaaaa tcaatccata
    83521 caatatcacc ttttttagga atataaattc tttcttctga cactataaaa tttctctccc
    83581 ttcaggagtt aaatcttccc attcgtcttt ctcataatac tcggcctctt ccccaccact
    83641 aaatggatct tcaatttttg gaactaacgt aattgttcca tcatcagaat acacaacgat
    83701 atattcttgg ttttctgaag gtttctttcc gttatcagaa ggtaaagtta ccactacaga
    83761 acttccttgt aatctagatt ttgtaacaag cattatcatc actcccttaa taaaagtata
    83821 ctatataaca ctaagtaacg caaaattccc ctttgtaaac tatctagaaa attgttttgt
    83881 ttaaagtata tcttattgga tataaataga aataaattgt agccagttca ttttttcttt
    83941 aactaaaaaa ataatccaag aaacattgaa cctatggatc caaaagctac ccaaatacta
    84001 tagctaaccc cccgctacct tcaattttgc agataaaacg ctttgggaga aaatttcaaa
    84061 gacaacaggc catcctatca tgcccgatta taaacaaaaa gctggctatt ccttttgctc
    84121 tgacaaattt caattgggaa agttcacgaa actagcaggt gaagaagttt caactgttcg
    84181 gatcaaagaa tgcccgcttc aaatagaaac attggttcaa cgaatttcaa ctagacaaga
    84241 ctttgctatt gtagaacgtg agatcgtagc tatttttgta gaagaaggga ttttacatga
    84301 tccaactcat atcaatgtgg ataaatggca acctcttatc tataaattca gagaatatac
    84361 aactgccaac cagtcgttaa ctttgaattt tagattccaa gaattcaaag agtcataatg
    84421 ataaacatcg ttaggtataa ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag
    84481 ctatacatta gaaaggtcga ctgtgaccct atagatgcag tatatgcagc ttatgagcat
    84541 ttcttctgtt ctctttgttt ttgggatctg tgctgaagtc tttttcgttt tttgccgctc
    84601 tttctttgaa aaatcgatta tgttatacct tctccattac taattcaggc atctgctgag
    84661 taatgatttt tcgcgcaaaa gaaatatctg ttacccaagg ttcgatttgt tcttcagtca
    84721 agacaagcgg cattcggtca tggattggtg cgactgtgcg gttaggttca gtagtcatta
    84781 tgattgattc tgccattttt tcatcctgat ggctacgata aaaaccgcca atatacacta
    84841 ttttttcctt atttgaaaac ataaatttgt ctttttcttc attccactca ttgggaaaac
    84901 acaacgattt tgcaaaaatg gttgatgaaa ggtctttttt tcttctactg tctctgcacg
    84961 ggcattaatc atcaattgtc cttttttaaa tccggtaaat ccccacttca tgatttccgg
    85021 agtgaggatg ttttcttcct cttttcttaa cgtcacaaca agatttgacg gaaaaacttc
    85081 tccagctgct aattctgctg cctgcttcgg ttgtttcgtc tgggcttctc gataataatt
    85141 ctgaaggagc tctgactcta gatcaaaaaa ataacgacca cacatcctaa tccctcccaa
    85201 tctttttttc tatcatacac tgcaacaaga agttcgcacc aacaaaacgc tttcaatttt
    85261 tgtagaacta aaaaagttgt gacaagtgac aaactctcca gtgaatggta ttctcctgcc
    85321 aactcctcgg tcacaagtca caatattcaa caaacatgag aagctgcttt ttgaaattgt
    85381 tccttgtgac tcggagtgaa acggcaggct tacgacctct gggtaaacgg tgttcaaaag
    85441 ccagtttctc ggtattaagc caaatttatg caaaaatgta gaaagctatt ttcacaaaat
    85501 ttttcttaat actcgaaact aagcgacttt ttcacaacct cttccttaaa cggtgttcaa
    85561 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tatgagcagc tatttttatt
    85621 tggctgttct tattacttga tgcagggcag ctttttcaca acctctccac taaacgatgt
    85681 tcaatcagct aaccttcggt attagctcaa aaaacggcaa aatatgagga actattttgc
    85741 cgtttgtttc tctaatactc aggtcaaagc gctgatttca caacctctaa tacacggtgt
    85801 tccagaagta gcttcttcga aaaataagcc gaaatttcac aaaaatttga gaagcaattt
    85861 tcgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc taattattaa
    85921 agaacctttt gcgaagttaa caatctttct ttgatcaatt gaaaattctg cctaagtagt
    85981 gatagatcct gtgtgacttt caacaataag atacttccct ggatttcagc aatcaacgct
    86041 ttggcttgac ggtctgcttc ttcatcggac agtttttctt cagaaagtgc caggatattt
    86101 tgtttcgtat acttgaccca ttgattgact aattctagta gcaacagacg gtattcttca
    86161 tccactgtac tcaactcaat aatcaaatta cctacaggac agccatgata agtgatctgt
    86221 gtctcatgat cagcgaaaat ccagtccaac atttcttcta atgcttcttc tggctgtttt
    86281 ccagcattta agatgtcttc gaacaattct gtctgccata cgtccatatg cgcatggatc
    86341 accgctagac aaacttcttt ttttgaagaa aagtaataat aaaattgacc ttttcctgta
    86401 tcagaagctg ctagaatatc tcggattgac gtttcatgat agcctttttt ataaataaga
    86461 tctttggtcg cttccaagat cttttccttt gttttcaatg atattctcct ttttcatttc
    86521 tcatagtcct atattataca gtaaattcat cattttttct tcttaatcgt ttaaaaaaga
    86581 ctgtgccaaa ttatctgaca cagccctcac tataaaactg ttctcatata gctagatgtt
    86641 cattgattca agaactgcga ggacaaaagc aattcctatc ttatgatagt tgctctaata
    86701 cttcctctgt tgtcatcact tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca
    86761 ttgcttcttg gccaggagca ccaattgcat ctgtcgctac cacaacattg aatccactct
    86821 ctaccaattc acgcatatgg gaatcgctac acaagtttcc gttcattcca ccaagaatta
    86881 ctgtgtcgat tccatttttt ctcaattgga gcgccaaatc attgctttct ggtccaaaga
    86941 ttttatgagg agagctgatg atcgtatttt catccaaata aggtttcaat tcttcgataa
    87001 aatcggctcc tgaaccttct tccactgatt catattgact ttttctagca aacatctgct
    87061 gctcaagcat catatgttct cctgcaccgc caaattgcca tttatggtca tgtgggtaaa
    87121 aataatgagg agaaataaag agtttgtatc ctttttcttt tgcttgtttt accatttcaa
    87181 tcatattttc gatcgtattg tatttttcta agatatcttt tgtcaaacca aagccaccgc
    87241 ctgctggttt caagaactcg acttgcgggt cagtgagaac tactgctgta tttttattat
    87301 tgaacatggt ggattctcca ttcgttattt attttaatac atcatttaga gcttcactca
    87361 ttgtcggatg agaatagatt tgatctctca ataacgtata aggaagtttt ccattcatag
    87421 ctagcgaaat caagttgatg acttcatgag aatcttccgc atagatactt gcccctagaa
    87481 tcaagtcagt ttcagggtcg actaaaactt tgaatacacc tttaggatct tctaatactt
    87541 gtgctttagg gacaccgctt gtcatatact tgaataattt gtaattgacg ccttgtgctt
    87601 tggcttgttt ttctgttaaa cctacattgg ataaagtcgg agtgataaat acactgtaag
    87661 gcacagcttt ccggttattc gttgttcgtt tattctcgcc cttcaactga tccataatga
    87721 ttcgataatc atctagagag atataagtga actgcaatcc gcctttgacg tctccaatcg
    87781 cccaaatgtt gtctgcatct gtacgaaggt attcatccac agcgattgct ccgcgatctg
    87841 ttagtttaac atctgtattt tctaatccaa gtgatgctgt acttggtttt cttccagttg
    87901 cagccaaaac ttttgacgct tggattgtta cttcttggcc atcttctgta aaggtgacgg
    87961 cagctgttga ttcttggtct gctacttgat ctacagatac acctagatgg aattcgattc
    88021 ccgcatttgt catgtcttct aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa
    88081 attcagaatg ggcatcaaga acgacaactt tagatccgta ttcattgaac attgatgcaa
    88141 attccaagcc aatatatcca gccccgatga tcactaattt ttccggtaat tgttcctgat
    88201 ccatcgcttg cgtagaatca atcaagtagc gacttgtatt caatcctttg attggtaaaa
    88261 tgattggttc agaaccagta ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac
    88321 cattattcgt cacttcgatt tgatggttag aaagaaaacg tgctgtaccg tccatcactg
    88381 tcccagttgc ctcatcgctg atcatatgat aatttttggc gcgaagcatg cccgtcaatt
    88441 tttctttccg agcaacagcc tctgtaaagt cgattcctct ttctccattg aaaatcaatg
    88501 atttagaagg aatacagccg atgttgatac atgttccgcc atacatacgt gttgactttt
    88561 caacgactaa aaccgattca ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct
    88621 ttccaaaacc gatcacaata ttttgatatt tttccatcat ttttccctcg cttctttttt
    88681 acctaccgat tggtacaaaa atatgataac cgataattgt ctattctcca aatcatctgc
    88741 tttatttgtc aaaaaaaacc agacaaaaag cggtcctttc acgtttttag tctggttcga
    88801 tttcctttat tcttctaaac aatcgttact tctacatcga tatttcctct agttgctttg
    88861 gagtaagggc agaattcatg cgcatcttct gcaatttttt gggcttcttc ttcgctgatg
    88921 ccatcgatat gcacttctaa tactacaccg atctgatagc cgccatcatc taaattataa
    88981 agagagacac gtgcttttac tgtggactct gctgtcattc ctgcttcttt gatcatatgt
    89041 tgtaccgccc cattgaaaca agaagcataa cctgctgcaa ataattgttc tggatttgtt
    89101 ccttctgcat ggattcctgg aggagtgatt ttcatatgca tcgagccatt tggtgcctcg
    89161 acttctccat tgcgcccgcc atggttgatc attgctgttt cgtatgcttt tttcattgta
    89221 ctgctccttt cgattgacca tttgctactt ggctataatt atagtgtatg acaagtaagg
    89281 cgctttctac aaaaattctg cttattcgaa taccagaatg ccgtcttcta ctatttttcc
    89341 aaaaaacaaa aaaatactac tcgtgaacaa cagcgtcata tttgttccaa aataaatagc
    89401 aatcttttct acataatctt ttatatgatt gattttaaga tacatatata ccagaaagtt
    89461 gaccccataa accaatactg ttaaaaaaat aaccatattc gttaccattt tttcctcctt
    89521 ttgctggtct ccctaccagc actcgattta accataccac tttttttgcc gtccaagcaa
    89581 ctagcctttc aaaaagactg gtttattctg ctgttaatga ttcaagatca gaaaaatgtc
    89641 cgaataattt tgctaatttt actaacgcca acttgttctt tccgaattca tcattttcta
    89701 tctgtaatac tagtaacggc tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt
    89761 atggctcttc tagatcatat cgaatacctt cttcattttc cgggtcgaag ttcatccctt
    89821 tttcttcttc caacagtcgc ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt
    89881 catcgctgaa caattttaat cggatttctt gtacttctac gggctgtttc aactctttga
    89941 tttgttcatc taatgtgata ccttttcttt ttaattctgg caaaagcatc aggatctttg
    90001 cgatgacata tgcaccatca tccagaaaat agttttcctt gaatgcagcg tgtccgcttg
    90061 tttcgatggc tagctgtgta tctttcccaa gacggttaag ttctaatgct ttattgatta
    90121 catttcgata gccggaaata taacgaactt ggatgcctcc tttttcttca atgaatcttt
    90181 gtagatgaga agaagtaggg gaattcgtca cgattcttgt tcctggatgc tcttttaata
    90241 cgattgtact taatactgcg atcaaattat ttcgattgat cactgttcca gaagcactga
    90301 caactgcaga acgatccaca tctgtatcga aaatgatccc aagatctgct tcatttgcta
    90361 aaacagcctg cttgatactt tccatcgctt ctttattatc aggatttggg atatgattag
    90421 gaaatcggcc atctggttcc aaaaattggg aacctgttga atccgcacct aagctattca
    90481 atactttttc agcaaagaat ccaccagcac catttccggc atcaacaatg attttccaac
    90541 catttagtgg tttgctttct agtgttccaa tccccttttt aatttttgtg actaaatctt
    90601 gcgcataagg tgtcaaaagg tctgcttttt ctacgcttcc agtttgttcg ctttttattt
    90661 tttgctgctg tgataggata aaagcaatat cttctttttc tgctcctcct tctgaggtaa
    90721 agaattttat tccattataa taatagggaa gatggctagc agtcagcata accgcagcat
    90781 cgcacgagaa ctgttcaaat tgagtggaca taaacatagc aggcgtagta gctaattcga
    90841 aatcgatgac atgtatccct tgttctttca gactttggat caacgcctct ttcagtgctg
    90901 gtccgcttat cctactgtca tgaccaatcc caatcgtcca ttttttattt ggatcggttg
    90961 atttcttctt tttctttatc cagtttgcta gtccccagcc gatctttttt accatgtctg
    91021 tcgtcaagtt tacttcatat ccttcaactg gtaatgcgat tcctcgaata tccgatccat
    91081 tttgcagcgc tttcatatct ttcatataaa agtcctcctc atttattccc tcattttttc
    91141 cagcttttct gcaaatcgct gtgcttcttc ttctgagcgg caaataataa tgaatgtatc
    91201 tacaccggcc atcgttccga caacttcagg gtaagccact tcatctagcc aattcgttac
    91261 cacatcggca ccatttcgtt cagtcaatac gataaccatg aactgaacag actggatacg
    91321 caaaacctcg cgtctaattg ctgtacgcaa acgttcttca tttaaagaaa cagatggctg
    91381 gttaaataat gtatagcgta ctattttgtt ttcattttga ctttttacta acttcatttc
    91441 tcgaatgtct cgagaaatcg ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc
    91501 aagcagctct tcctgtgtcc caataggttg ttctgtaatg atctggcgga tcagtgcttg
    91561 tcgctgtttc tttttcatat tagacacctc tcaatgttga ttatagcaaa agataagtaa
    91621 tatttcttca tattttggta ttttttactt ttattttttg ttttcattca ggttgctaac
    91681 ctttttctat tttaacacgc aaaatcgtct tcattttttc aggtgctgat tttcttggat
    91741 cgctgatgta aatctctttg tgttctttag aagctctttc atagccttct tttgcgatga
    91801 atgcttctaa tttctcaaac gttgctggtt cttcggcata gggcccgacg tgtaagattt
    91861 gggcacaaag accttcttcc atctttttga atactacttg ttctttcaag tcttccggaa
    91921 gtttgctaga acgctgaatg gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc
    91981 ggatcatcaa ttgataagaa aaatgttctt ttttcatcac tggttcatgc aaatactttt
    92041 cttgcagtcc ccattgtcct tccagtggat agacagtata catctgataa tcaggaatca
    92101 gccaattttt tttaggcgac atgcgtattg catagctgac tgcatataga caggctactc
    92161 ttcgtttaaa gtcttcctga ttcgggtcgc cgatccctct gatgctaaag aatgattttt
    92221 taggaacctc tagtatttgc gggctttttt tcatactata gctcttgtct ttacgccatt
    92281 caattttttc catttttctt cctccgcgaa attccattta gttatttatt tatcatacct
    92341 ctttttgagt gacttggcta atcgtgttga cactattttt cagtttgtgc tagaataagt
    92401 gaagtaaata aatcgtacag ataacacgtt tcggcgtgtc gagagagagg cggtttctat
    92461 ttttataata gaaatcactc tcttttttta cgaaattttt tagaggtgat gtaaatgaca
    92521 aaacaaaaac agctgctttt agtacctgca gtaattgcaa cagggatgat gtcttttgcg
    92581 ggcgtattga tcgagacggc catgaatgta actttcccaa ctcttatcag acagtttgat
    92641 ttaacgactg cacaagtcca atgggtaaca acgatttatc ttttgatgat ttcgatcatt
    92701 gttccgctgt ctacttattt gaatcgcaat tttagtctca aaaaactctt tttagcttca
    92761 aatctgcttt tcttggcagg tataatgatc gatttcttct ctcctacctt catggtccta
    92821 ttgtttggtc gattgctcca aggtgcagcg acaggtatcg ctcttccgtt gatgttccat
    92881 attatcttga catttgcccc cctcaatcga cgaggcgcga tgatgggtgt cggtactttg
    92941 acaacggcca ttgctccagc aattggcccc acttatggag gcattatgac ttcacatttt
    93001 acatggaatc atatcttcct gtttcttgtg cccgttttga ttctttcttt gattatcggc
    93061 tggtttgcta ttcccgagat ggcagtacaa aaaagtggtt atttggattg gataagcgtt
    93121 ttaggaattt gtcttttgtt tagtggaagt ctaacatttt tgagtacgtt gggaacagtt
    93181 tccagctgga ttgctttaat catcggcggt attggctggt tcctttttta ctatcgaagt
    93241 aaaaaagtgg agcatccact gatccgactg tctattcttt caaataaaac attccgcttg
    93301 tttttgattg gcttcttagt ttatcagttt ttattacttg gtgtatcttt tgtcttgccg
    93361 aatttccttc agatcgttca aggaagtagt ccttttgtcg ctggattagc gatgcttccc
    93421 ggcgcagcgg ttggtgcttt gctttctcct ttttccggga aaatgctgga tcaatatggt
    93481 ccgaagaagc caatttttgc tgggctgatt ctttctttga ttggttggct agcattattc
    93541 ctactcatag gacacgcttc agtgggtgta ttgattgctt gtcatgtgtt ttatatgatc
    93601 ggtatcggat tatcttacag caatatgatg accaccggaa tgaatgcact gaatgaagaa
    93661 ctacaaggag acgggaacgc aatgttcaat accttgcagc agttttctgg cgctgtggct
    93721 acttcattag tagcggtcat tatcaattac gtccagcatc atacttccca taactatgaa
    93781 gtgtctacta cattaggatc aaaagcagca ttaggcgtct tgttgctgtt gcttctcgta
    93841 agctttgctc gattcgccta ttatctgttc tttgctaaaa aagcgtagat tccatatacg
    93901 gcaggtgttg catctgccgt ttttttgtgt gaaaatggtt gtttgtaaaa ggaggctttt
    93961 ttatggaaaa aattgccatt atcggtggcg ggatcattgg tatgacccta gccagttact
    94021 tagatacatc aaaattcaat gttgctttat ttgatgaagg gacaggacag gcaactaaag
    94081 ctagcgctgg gattatctcc ccttggttgt cgaaacgcag aaacaaacaa tggtatcgtc
    94141 tggctaaaga cggcgctgct tttttcccta aacttataaa agatttccaa cttgatcaaa
    94201 cgatttacgc acaatcaggg acacttttgc ttcgacctga aaaagattta gctgaattgg
    94261 ctgttcttgc cgagaaacga aaagaagaag cgccagaaat tggaaacatc gaatggcttt
    94321 cacctgaaca gacatctcaa gcacttccgt tattgaaacc agcagtttca ctgcgtatca
    94381 gtggtggtgg tcgtctggat ggaaaagcat atttagaaca tcttggtcag cgtttagcac
    94441 aaaaacaaat ggagcagatc caggcaaaag tcactttgca taagaagagc gattcttggc
    94501 tcatcaaggg accgtttgga gaatacacag ctgatcgtgt aattttgaca cctggcccgg
    94561 cacttaagcc tttattacaa gaattaggct atgctgcaga tatacgtccg caaaaagggc
    94621 agctcttagc atttcagaca tcttataaga tgagtcaaga ctggcctgtt gctatgcttg
    94681 acggagaagc tgatttcatt cctttcatgg atggaaagat ccttttaggt gctacccatg
    94741 aaaacgatca aggctgggat ttggctccta ctagcgaagc ttataaggga ttgactaaga
    94801 gtacagaaca gttcttgact gatccagatc agataaaaaa ctggccatac gagttccgtg
    94861 taggtacccg tgcttatacg tcagattttt ccccattttt cggcgtactg ccagatgatc
    94921 caagcttact ggctgctagc ggtctaggct cttctggctt gaccacaggt ccttatatcg
    94981 gctatctatt agccaacttc ttaaatactg gtcattggcc tacggaagat tatcaaaagg
    95041 acatctccac ctatattacg aaaaatccat catagaaaaa cagctttttc aagtaaggat
    95101 cccgagcgat attgcgcatg gattacttct tgaaaaagct gttattttag ttcaatttct
    95161 gaatcaaatt ctccaaactt tcttttgctt catctggcaa gagatctttt cctatctgag
    95221 cttcaatgaa tcgtaaacga atatcaagtc gttgtttcac cagattttta taggacgtat
    95281 cctcaaaaga aacaggaaaa tctggtatag gtaaatagtg gatgtcttca aatggaccaa
    95341 acgacttgaa ttctgccgtt tgttgcacga ttctttcaac gattgacaat gtcgtttcag
    95401 gtttgatttt tttatcatcg aaatatccag tattcaggac atagcaggct gtttgctgtt
    95461 tcaaaaacaa ctctcgaaaa gcttgatagt cttccctaag aggatagaca cggaaaggat
    95521 tagcaaatgg ttcaatgact agctcatcta gctgtctttt tgtagtgata ttttccgcgt
    95581 ctgatcgttt tgttgctaat gttgcaccaa aagacgctgc taaaactggg tcattgatct
    95641 tgataattgg cggaagcgaa tcatctttca tgatccaaaa aacagcatcg atcttttcgc
    95701 taagatgatc gactcggtcg ggtgtcgcat aacgtgattt gactgtccgc ccatttccgt
    95761 ttcgtatatc tcctgttact aggacttttt ctcctttact tgtacatgtc acgcccacat
    95821 tctgacaagt aaggaaagaa gaaatggccg gatcatcaga cggatagtct tgtgttttat
    95881 caaagtaaga aggttccaag gcagtagcaa aaccattttt tcgagaaata acgaaagcat
    95941 cgtcatgcaa gatcgaaaca gagtgacctt ccgtatgttt tgctaaggta atcgttgatt
    96001 ttccagaacc ggacaaccca aatacagcca tcgtataggt ctggtcatta ctagcatatt
    96061 gtttcatccc accgtggcag gcaataaagc cattgcgatt tcccaatgcc caagcaagcg
    96121 tcaaagtcgc tttttttaat tctccaaagt aacgtaatcc tagcacagcc gctgtattat
    96181 ggagagcatc aaacaaaatg agtccatttg gaaatgtttc atgtgtccat tcgggatcac
    96241 aaaagatata aagatctccc tcatcaaagg aaacagactt ttgataagtc tctaagatct
    96301 tcgaattcgc tggctgaaaa ttcagcaaat aagaatacaa attgttctca aatccttctg
    96361 gaatcagcaa atgactttgc acagaaaatt cttcagatag gccaacgatt acttttgtat
    96421 ggtaaaactg gcgcttgcga ctttgataca cagcttctct taaaattttc tcgtatttgc
    96481 tttgttcctt gtctaagtcc tcaaagatcc gccgagcact tgctgttctt cccacaatgc
    96541 ttccatcatt gaatactagt gtcctaacat cagctggtaa atctagttct tcagcatgtg
    96601 agattgttaa atctgtgatg atcgttcctg gactcccttt tgctagttga taagctgtct
    96661 tcctatcaaa aacttcatga acattattac cgtaaaatgt cgtttctaca atcgatcgaa
    96721 tactggataa cagtggattt ccacttgtga tttcgtttaa ttcgagactc tcttttgtac
    96781 tcatggctcc tcctcattcc ctaaacaaaa aaacgttttc tttattatac attattcgag
    96841 tttttatttg tactgctgcg ctgtgggaag caaacgagtt atttttcaca caaaaaaacc
    96901 gagaacttga ataaacaagt ttctcggttt catcattttc cttttatcgg cttagtacca
    96961 gccgtttgct aaccagaatg ttttagcagc atcccatgaa ccataacgag atgttacata
    97021 ttgttctgct acacgttctt gattggcagc tgaatagtcg ccgtttaagt atgaagcatc
    97081 taattgataa cggccgatgt aacgtccgtt agtagctgtg tatgaaccgc ctgattcttt
    97141 ttgtgcgatc cattcttttg cagagcttga agttggcgct gttgcagcag ctggggcagc
    97201 aggagctact tcaactgttt caacaggtgc aacgtatgta tgttcttgcg ttgctgtttc
    97261 agttgtagat gctgtatttt ctgttgtttt gttttctgtt gttgctgaag aatcatttga
    97321 agttgggatt gttaattgtt caccaacata aatgcggttg atgtttgcga tcgaattttt
    97381 ttcagcaatt gcatcgatca ttgagttgtc tcctgcaaat ttttgtgaga tcttagataa
    97441 tgaatcacct gattttactg tataaacttc atcagcgtga gcatttgtag ttcctacaaa
    97501 cattgcagta gcaccagcag caaaagttgt acctaaaaca attttcttaa atgaattcat
    97561 attaaactcc tttttttctc cgttttttat tctttcgacg ctattaactt tatcatttag
    97621 aaatatttca taggtaaaag aaacatgaca tttaatgaca aaataacgaa ttatttaata
    97681 tttgtaacat ttaaacaaat atttttttga tacaaaacca taaaagcctt gttgtataag
    97741 caaagtaatc gtttttctat gtttttttat ttttgaatga aaaacgcaga ttctgtaaca
    97801 ttcactgcaa taatccataa aaaaaagcaa aaaaattttt gatttttatc aaattctctt
    97861 aaaaaaatgt aaaaaataca aaaaaaccag taattgttac aacaattact ggacaaaaac
    97921 tttgaataat gttaactatt tttttatttt aactttctcc gcaataattt ctgggcatgt
    97981 tccaattcgt ttataacgac ttcttctgtt tctttagcta atatttcatc taatacatca
    98041 agccattttt ccggttcttt tgttcctaga cgtccaatag cccaagctgc tgttcctctg
    98101 atgacagggc ggacatctgt taaacattct gaaatctcag gcaatgccgt tcgatcacct
    98161 agattagcta aagcaatcaa tgcgtttctc tgcaaaggtt tcttcccacg ccatgaacca
    98221 gctaaatgcc caaattgctg tttgaagtct ttattagaca tcgaaagcat tggctttaat
    98281 tttggatata tttcgtctac ttttggttcc atctcttcat gaaaatgaaa atcttttcct
    98341 tgattgtaag ggcagactaa ctggcagata tcacatccat aaatgacatt tcgcattttt
    98401 ttacgatatt cttccggcat catccctttt gtctgagttt gataagacaa acatcgctgg
    98461 gcattcattc ttccgtcacc aagcaatgct tttgtcggac aagcagtcac gcagcgcata
    98521 cagtcaccgc aaccaaattc tcctggttta tcaggctcaa atacaatatt agtaacgatc
    98581 tcaccaagat agacaaatga accgaactct tcagtgatca acaatccgtt tcgtccaata
    98641 aatcctaaac cagctcgctg tgctacagcg acatcgatca gttctccagt atctacttgc
    98701 ggagctagac gccattcctc ttctttttgc catttttctg ctcttgtttg gatgaattcg
    98761 atcaatcggt tcaaacggtc tctgagtata tcatggtaat cgatccccca agaagcacga
    98821 gcaaactgcc cgcgtttttc atccctaggc acttcttcat ggatcctagt aggatacgca
    98881 agtgcaatgg aaatgatcga tttcggctga tcaaatgtca tttctggata aagacgctca
    98941 tcgatatttg gatgttcaaa gccagaagta tggccagctg ctttttgttc ttccaacgat
    99001 tcttttaatg aatcaaaagg ttccgccgtg gtgaacccga ttttgtcaat tcctaatcgt
    99061 ttgctttctt gtatgatttc ttcttttaat gtcatggtct tcctcgcttg ctgttaacgg
    99121 ctgtataacc cataatatag tttttctttt ttcagctgga caaactggat ctgctgatcg
    99181 gcaatcttct tttcttccat ccattttttt cttgcagcaa atacttccca ataatttgtt
    99241 gaaattaatt ttcttttgtt atctaatgca ttaaaaaaat tcaatgaaac tggttttgta
    99301 cttaacagtt catggagcct tacctcttcc catggcgaaa actcagacag atcgcgggaa
    99361 tacaatactt cttcatagag atttttttgc tgtgtgtacg tgaatgtttg cgggattttc
    99421 ccaggcctag caatttctac tagacgatta taaaacatat tcattaattt gctgttggca
    99481 ataaattgac ttttataata ggccgactgg atctttttga ttactccttc tgctttgatg
    99541 actgaaaata atgcaggcca tgctttgacg gttatttcgt cgttttgttt aactaatacg
    99601 ccaggtgtga agccgactgg agaaaggaac acaaaataac cgataccggt attttcatct
    99661 aaaggctgaa attcatcaaa caaccatttg cctatgtaca gctcttcatc tggttctgtt
    99721 gtctcatttt gatttgctat gaataattta gctaattctg cttcaagaaa ttgaaggtct
    99781 tgatccttgt cggtattttc ctgctggctg atcaatcgaa agacttcttc tttaatcgta
    99841 tatttatctt tacgtgtaaa attcatagcc acaccttcct tccttactct aactataacg
    99901 gaatttcttc aaaaaaggta tctgtacgac gaaaaacagc ataatttttt ttcatatctc
    99961 ttataaaaaa tgcaaggtct gctcctcaag ctagaccttg cacttttcag ctttcttttg
   100021 tttgtgacaa accttcatgg atcgtttcaa tattccattt catcatctga tagtaagaat
   100081 ctccttgttc tccttctttt gctatggaat cagtgaacag tttatcatag attttcaaac
   100141 ccgtttcttt tgctacccgt tccatgcttc ttgagtctac actggtttcc acgaataaaa
   100201 ccggtacttc ttttgctctt atctgatcaa tgatcgcttt catttgatca ggcgtacctt
   100261 gactttctgt attgatctcc catatataag ctgctggcaa atcatatgct cgtgaaaaat
   100321 acttgaatgc cccttcactt gttactaata attttttgtt ctcttcgata gaagcaaaac
   100381 tttccttcgc ttgtgtatct aattctttta gtttttccac atatgcttct gcattttttt
   100441 tatagagtgt cgcattttct gcatcttttt cagagaatat acgtgcgatt tcctccacat
   100501 attttattcc gttagatagg tctagccaag catggggatc tgcttttgta tgttcttcac
   100561 cgctagttaa ataaagaggt tctacatttt tgctaactgc aaaataatct tttccttctt
   100621 cttttttagc cgtttccatc aagttatcga accagctgtt acctgtttca agattcaaac
   100681 cgttgtataa aataacatct gcatcgcttg cctttttgat gtcttctggt agtacttcat
   100741 attcatgcgg atctgttccg actggtacga tactgtggat atctatttga tctgttccga
   100801 cctcttttgc catgtccgcc aagatcgaat tggtagccac gactgacaac ttttctttac
   100861 ttccttcatc cgcttggtca gaagcctgct ttccgcaacc ggctaatacc aagaaactaa
   100921 ctgccaagat taaaaagagt gatttttttg ttttcatcta tctgcttcct ttctgaaata
   100981 aaattccttt tgttggagaa aataaaaaag caaggataaa aaatgcggta catgctaaca
   101041 cgatcgtagc tcctgatggc caattgtaac tataactgaa aaacacaccg acaactgcac
   101101 ttagcatacc gattcctgca gctgtaatga tcattttcag taaatggttc gttagcaagt
   101161 aagccgtggc ggctggtgtg atcaacatgg caatcaccaa gattgttcct actgtctgta
   101221 aactgactac agccactaat gtcaaaaaga acatcaaaag ataatggatc agcgatgtgt
   101281 tcagcccata agcttttgcc attgtcggat cgaatgatgt gatcttcaat tctttataaa
   101341 agaaaaagac aaatatcaag acgattccac taacgagtgc tgtcagcaac aaatcgcttt
   101401 ccctaacagc taagacattc ccaaataaaa tatgatacaa atctgtcgca ctctgggcat
   101461 atgaaatcaa gataatccct aatgcaaaaa aggagctaaa gacaattcca atcgctgtat
   101521 catttttcaa tcggctccgc tgagtcacga aaccaatcac tgctgctgtt agcatcccaa
   101581 aagcagtggc tccaaagatg taactaaaac caaacatata agaaatggct acacctggaa
   101641 gaactgcgtg agagatagcg tctcccatca aagacatccc tcgtaaaata ataaaagaac
   101701 cgatgactcc agaagcaagt cctacaagca tggaagtgac caaagcgtat tgcaggaatt
   101761 gataattcat taatccatca ataaaggatt ggatcatttt ttctctcctc cttttactaa
   101821 atgtctgatg atctcaccat aggccaattg aaggttcttc gatgtaaaga cttcttgtac
   101881 tggaccggaa gcgatcagct gtttatttaa aagaataacc tcatcgaaat attcttctac
   101941 tttatgaaga tcatgatgga cgatcaaaat cgtttttcct gaattcttca attcctgcaa
   102001 gatgtcaaag atctttcgtt cacttaacgc atcaatccct acgaatggtt catctaaaaa
   102061 gatccattct gctccttggg ctagagctct tgcaataaaa actctctgaa gctgtccacc
   102121 cgatagttcg ctgatctgtc ttttggcata ttcttccatc cctacttttt tcaaagcttg
   102181 tcttgcacgt tctttttctt ttttcccagg tctttgtcca attcgtaaag atggatatgt
   102241 tcctaaaagt acaacgccta atacatcaat tggaaaggaa agatccaatt cacttcgctg
   102301 ttccacgtag gctatttttt tacggactga gtttaccgac tgtccagaaa aggtgacttt
   102361 accagtagta gctggtatca actctagcaa agatttcata aatgttgatt ttcctgcacc
   102421 gtttggtccg ataataccgg taattttttg tggatttatc gtcaagttga tagttttcaa
   102481 aacagttttc ccttgataag cggctgaaag gtcttgaatt acaatggccg tacgttccaa
   102541 atcttacact cctttttagg tttacctaac tttttattta aatatagttt aactaaaatg
   102601 gaaagcattt tcaagtagaa tgatgaaaaa gtttttttcg aattttcctc gcattttatg
   102661 aaaattttct gtagaatcac atcaagagtt caataaggct aacctaataa tgaaaaacat
   102721 gtgttgaaac gtttgattat tttttcttgt tgactcaaca acgaaaggag tttttgtatg
   102781 gaagaagaaa agttaactcg aagtcttagt gcccgtcata tccaaatgat cgcactaggt
   102841 ggaacgatcg gtgtcggtct gtttatgggt gcctcctcaa ccatacgttg gacagggccc
   102901 tcagtgatgg gagcctatgc gattgcagga ttctttttgt atttgattat gcgtgcttta
   102961 ggcgaaatgc tttacgttga tccttcgact ggttcttttg caaattacgc gagcgagtac
   103021 atccatcctg tggctggcta cttgaccgct tggagtaata tttttcaata tattgtcgta
   103081 ggaataagtg aagtgattgc tgtaggatct tatatgaatt attggtggcc tgatttgccg
   103141 gcaattattc ccggaatcat tgtcgtcttg tttcttatgc tggcaaatct tatttctgtc
   103201 aaggcgtttg gcgaattaga attttggttt tcgatcatca aagtcataac gatcattttg
   103261 atgatcattg caggtcttgg ggtaatctta tttggatttg gtaatcatgg tcaggcagta
   103321 gggatttcaa atctttggaa aaatggtgga ttcttcactg gaggcgtcaa aggatttttc
   103381 tttgcattat cgatcgttgt tgcttcctat caaggaatcg aactgatcgg aatgactgct
   103441 ggtgaagcag agaatcctaa aaagacgatc attgaagctg tccagtccac tatcggtcga
   103501 atcttgattt tttatattgg tgctattttt atcattgtga gtatctatcc gtggaatcaa
   103561 ttgagtgaga ttggttcacc ttttgtacaa actttttcta aagtcggcat tacatttgct
   103621 gcaggactga ttaattttgt cgtgattaca gcggcattat caggttgcaa ttcagggatt
   103681 ttcagcgcaa gtcgtatggt ctatacactt gccataaatg gaaagatgtc taaaaaattt
   103741 ctgaaactat ctcgtcacgg tgcgcctttt tatcctgtcg tagcaatctc aggtggaatc
   103801 ttaattggtc tgatcttaaa ttatcttcta ccaatgttca tcaaccagtc agaaaatatt
   103861 ttcgttttcg tatacagctc aagtattttg cctggtatgg ttccttgggt agtgattttg
   103921 atcagcgaga ttcgcttcaa aaagaagcac gcagataaaa tgcatgatca tccttttaaa
   103981 atgccactat ctccttatac gaattatgtg acacttgctt ttttagctat cgtattgatt
   104041 ttcatgttta tcaatcctga aacgagaatc tcattgatta ttggactcgt tttcttgctt
   104101 tacatgacga tccattactt tgtacgcgaa aaaagaaccg gaaaataaaa aaagaacgaa
   104161 gcttcacctt agtggaagct tcgttctttt ttattgcttt tatcaattca attttagcgt
   104221 ctcaccggga gtcaggaaat aattctccat gctcatccca ttcagcgaca agatcgtttc
   104281 tactggtacg ccagttcgtt cggctatttg atttggacct tctccttcca aaactacggt
   104341 tgtcgcagcc tgtgaagtcg cgctgttggt attagtttca gaggaatctg ttgtgtcttg
   104401 tgttgttcga gcttgcattt cagaagcttc taccgactct gctgtctcag aatcagaaga
   104461 tgttgtgtct tgtgtgcttg ttgactctgc ttgaagagag gcgctagtct gcaaataaat
   104521 atcggaaatc ttagcgacat gattcgtata attagccgat aattgattga tcaaagtatc
   104581 taagtctaca ccgtctttat tttctgctgc ctgatacgct gcacgtaatt ttctgatccc
   104641 ttcgtcggag attgcttgaa gctcacgtgc tttttggtta gcaactgctg ataaaccagc
   104701 tattccctct tgatttccct gaatttctgt ctggtattct tcaatcaatg caggcgtctt
   104761 ttcttcgatc tttttcgaat aatcatttac gattgcttga agttgctctg gcaaaccatt
   104821 tgctgttttt tcttcagaag tttgtgtctc ttttgtttta gttgatgact cacttgtttg
   104881 tttcgtctct gttttctttg tcgttgtttc cgttatggtc gtacttttcg cttctgacga
   104941 attttttcca tgaaaatata gacccgcaac tcctcctgct atgatcaaaa acacggcaac
   105001 tgctgcccca atcatgatca tccgcttacg agctgcctgt ttttgctgtc ttcttcgggt
   105061 catccgaaca ttttctcccc actcattttc atcatacatt tttttcacca ccaattttta
   105121 tgtataatag cgttatcaaa cgcttcatat tcttattgta gcaaataatt gtcgctgtgc
   105181 acatttttat ctttgttatt tataagaaaa tttcaccagt tgagatgatt ccaagattgt
   105241 ccgtcgattt ctccttgcag ctgcattgtt cgttcgtcta tctcagccat cagtttcttt
   105301 atttcatata agagcgcacg gtcttgatat tctgattttt cgcttaattc atctaattgt
   105361 tggatcagcc aatcatttgt cataatgaag ttcctttcat ttcttgcagt gtaaaggtca
   105421 agtcttcgat ctgctctttt gcctcagtca gtgcttctac gatatatgct tgtttttcag
   105481 attcttcttc ctgcattttc tgattttcct gtactctttg aataaaccag tcaatccgct
   105541 gagtcagcga tggtttgcct tccaatgaga gatactgctg ataagcaatt agcttctccc
   105601 aacgtttttc ctgggataaa tacataaatt gtgctaaaac gaatggcgga agataggtca
   105661 tatggaattt atttgcgatt cgctgatacg gcctcaaaaa ttcggaaatc gtatattctt
   105721 cttttcctcc agcttggtat tctttttccg ccacacctgt tgtcaatacg attcctagtt
   105781 ctttcccttt taatacatgt gctgctcgtt ccaagacatt atcttgccaa atttttaaat
   105841 gagcaggaga actataccag taaaacggaa actggaaaat gatccgatca tgctgggcca
   105901 agagctgtag ttcagtctct atatctattt ttccgtctgg ataacttgat tccaaatgat
   105961 gccaagtagc tggtaaacca gcagaagctt ctttgaaaaa ttgctgattt aaagattctt
   106021 cgatcgttgg atggctaatg atgataagtg tacgcatccc ttttcctcct ttttagtctt
   106081 cgctttacag tgtagcataa ccgccacaag tttcttttgc cgatgcttgt cattttaacc
   106141 agactaatca ggttgtccaa gaaactgcgg tttgtttttc caactgtttt ttcaaggtat
   106201 ccaaagcaat attcttaaaa ttttcgtttt tcatacgttt acgatagttc gtagccgttt
   106261 ctccggtact ctttttgaac attcggctaa atacgactag actattgaac cctacttgat
   106321 aggcaatact ttccacggat tcacccgtca gagaaagaag aaacgcccct cgattgatcc
   106381 gtaccccgat caaatattcc ttgatactgg tacccatatg atttttgaat actcgcgaca
   106441 aatggctccg attgaccgct aaatgctggg cgatttcctc aacagacaat ttttcagcat
   106501 aatgtgcctc gatgtatttg actgtttcaa cagctaaaga ggaatgaacc ttttgtacac
   106561 caccgctgac ctttccgcca tcttttaaaa ggactgataa aaaacggtag gttaatgctg
   106621 ttaactgtaa ttcattttcc aaggtttctt ccgtatcttt catgcattct aaaataatgt
   106681 cgatatattt ttgtatgtca gaagagacca tcgtgtattg gtcttctctg aaaagcgact
   106741 gccgaatgat ttcttctgca gcactcccac caaatgaaag ccagcaatac atccacggat
   106801 cttctccatc tgataagtaa aacgtcgagt ctcctggacg aatcaagaac agatcacctt
   106861 ttttcaattg gaattgttga tttttcacat gataagatcc tttgccttcc atcacgacat
   106921 gcaggatgta atcattgcga atagcaggac caaaagaatg aaacggcatc gttttagaga
   106981 aaccacaaaa atcaaaatac aattcttttt ctacttgttg atgttccttt tttaaaaaaa
   107041 tcgattgctc cacgtctatc cctccttact cctttagtat aatgcaacaa aaagttaaat
   107101 aaaagtcaca gaaatatatt aaaaaggaag cgatttcttg ttaagtttaa gtcattaaaa
   107161 gatctttgtt attcgttgta accggtttac ttagtattat atattgaaca ggagaggaat
   107221 acagattatg aaaagcaaaa tgatccaacg tgtgtcctac gctttaggcg cttttggaca
   107281 cgacacattc tatgttacat taagcactta ttttatggta ttcgtgacaa gccagatgtt
   107341 cgcaggaaca gataaggcaa cgaatgcaaa aatgattgct acagttacaa gcttagttgt
   107401 aggtatccgc ttagttgaaa ttatttttga tcctttgatt ggtggcatca tcgataatac
   107461 tcgtacaaaa tacggtaaat tcaaaccatg gttagttatc ggcggcgttg ttagttccgt
   107521 actcttggta gcaatcttta ccaatttctt tggcttagct actcataata cgactttatt
   107581 tatcatatta tttgcaatcg ttttcatctt attggatagt ttttattcat ttaaggatat
   107641 cgctttttgg tcaatgattc caactttgag tacggaaaca aaggaacgtg aaaaatttgc
   107701 tacgtttgct cgtttcggct cttctctagg tgcaaatggt actactctag tcgttgtccc
   107761 tatcgttact ttctttacct atcttgttac tcataaacat attgaaggcg cttcaggctg
   107821 gttctggttc ggtgtgattg ctgctgttat ttcaggcggt actgcgatta tcactgcctt
   107881 gggcacaaaa gaagtcgata ctgcgatccg tcagcaaaat gaaaaagctg ggatcaaaga
   107941 tgtgttcaaa gcagttgctc aaaatgatca gttgatgtgg cttgcccttg cttatatcgc
   108001 ttatgcgatt gccaatgtag caacaactgc cgtattattc tacttcttca aatatgtact
   108061 tggccaacca actgaatttt ggatcgttgg tctagttgct gccttacttg gtttagtagc
   108121 tgttccacta ttcccaatgc ttacacgcgt catctctcgt cgctacgttt accttggagg
   108181 gatcgcaatg atgatttctt cttacttttt ctttacgatc gcaggttcaa gtttgccaat
   108241 cgttatcatc gggctagtat tgttctactt ccctcaacaa ttgattttct tatccgcttt
   108301 gatgacgatc acagactctg ttgaatatgg tcaatggaaa aatggtatcc gtaacgaagc
   108361 tgttactcta tcaattcgcc ctttactaga taaaatcgct ggtgctttgt ctaacgggat
   108421 cgtagggttt gtcgctagcg cttctgggat gactggtaat gctactgctg ctgatatcac
   108481 tgctcatggc gtaacgactt tcaaagctta tgcattctat gctcctgctg ctttgatgat
   108541 tttctccgct attatttttg cttggaagat tacattgaca gagaaaaaac atgcacaaat
   108601 cgttgagaaa ttggaaaaca aattggctcc agctgataca atggaagatg aacttcacga
   108661 tgcagtagtt ccttcccatt aagaaaggat cttgaaaatg aagattacag aaaaagattt
   108721 tggccaaggt tatcacttga taaccttgga gaacaaaaac aagctagcac tttctatctc
   108781 tgatttaggt gctagaatcg tcagtttaaa atcaaatgat cgagaattag ttttgggatt
   108841 tgacaccgct gaagaatata tcgaaaaaga tccgtatatc ggtgcttcta tcggtcgcac
   108901 cgcagggaga atcgaaaatg gccacttttc tctcaatgga aaaacttacc aattagccac
   108961 agatccaaaa actggacata atctgcatgg tggtgctcct ggatttgaat taaaaaaatg
   109021 gtcttatgtc attttgaatg gcgaaaatga agcttctgtc atttttacta ctacaagtcc
   109081 cgacggagaa catggttttc caggtacaat ggatgtggaa atccgctata ctttgacaaa
   109141 agataatatc tggcgagtga cctctcgcgg caccagtgac caagatactt tattcaatcc
   109201 gacaaatcat gtttacttca acttgacggg agatgcttct cagtcaatcg atcaacatga
   109261 gctttggctc aatagcgaag cttatgctcc tttgcgaaca gatagtattc ctataggggt
   109321 aaaagaaaat gctgcaggaa gtgctttcga ttttcaaata cctaaaaaat tagcgtccgt
   109381 ttttgctagt gatttggatc aaaaaaatct tgttgacgga atcgatcatc catttttctt
   109441 aaaagaaacc ggcttgggta aagaagccgc tcgcttgact agccccgata aaagaatcca
   109501 agtagatatt gctacagatg cttctagtgt ggttattttc actgcaaatt tcggcacaga
   109561 aacaccagaa atgcgcaacc gaaaactggc acatcacggt ggcatcacat ttgagactca
   109621 aacagctcca ggtgcagagc gcttctcagc atttggttcg attcatttaa aagccggatc
   109681 agtatttgaa acagtgacag aattcaaaat caaaacaaga aaggaataac tcatcatgga
   109741 aatcaaaaga agcttaaaca caaaatttgc cgaaacattc ggacctaaaa aaactacaca
   109801 atacttctca ccaggacgca tcaatttgat tggtgaacac acagattaca atggaggcca
   109861 tgtcttcccc gcttccatca cttatggaac gcaaggtgta gcagcacctc gagacgataa
   109921 taaaatatta gtttattcca caaactttga cgatatcggt gtcattagtt ttactttaga
   109981 tgagctagaa tatgataaaa aagcaaactg ggcaaattac gtaaaaggaa tggtccttaa
   110041 attaaaagaa gctggacact caatcgatca tgggtttgag ttattagtgg aaggaacaat
   110101 ccctaatggt gcaggacttt ccagtagcgc ttcattagaa ttattagtag gtgttgtatt
   110161 agaagatctg tttgatttaa aaacagatcg cttggaacta gtccaaacag gtaaaaaagt
   110221 agaaaatgaa ttcatcggtg tcaattcagg tatcatggat cagtttgcca tcggcttcgg
   110281 tgagctagat catgcaatct tattagatac aaatacgctg aaatacgaaa tggttccagt
   110341 gaaactagat ggttatgcaa tcgtcatcat gaatacgaat aagcggcggg aattggcaga
   110401 ttcaaaatac aatgaacgcc gtagcgaatg cgaagaagcc ttggcacgtt tgcaaaaaac
   110461 tttgcctatc tcttctttag gagacttaga tgaagaagaa tttgaatcaa ctattgacca
   110521 aatcggcgat gatacattga tacgcagagc tcgccatgcc gtttctgaaa atcagcggac
   110581 tttgaaggca aaagctgaat tagaagctgg gaacttagaa gcatttggtc aactgttaaa
   110641 tgattctcac cactctcttc gctatgatta tgaagtaact gggatcgaat tagatacact
   110701 agtagatgct gctcaaaaac aagaaggtgt cttaggtgca cgaatgacag gagctggatt
   110761 tggtggctgt gcgattgctc ttgtcaaaga agaaaatata cctgccttca aaaacaatgt
   110821 ctatgatgaa tacatgaaag ttgtcggcta tgctccggaa ttttatgttg cacacattgg
   110881 aaatgggaca acaaagatcg atccagaagc tgttcatgtt tgataaaaaa atcaacgatc
   110941 tcagctaaaa acaaatagat aaaaataacc tctcagcaat ttccaaatgt gagccttttg
   111001 ctcgtatttg aaaattgctg ttttttattg acacggaaag agaacgtgtg ttctaattgt
   111061 gttgaagagg tgattgttat gtgggcgaat caaaatccgg tatttgttta tgaaaaagaa
   111121 ccttcaagag atattttatg tattgactgc aaatcttttt acgcctccgt agagtgcgtt
   111181 gaaaaggatc ttgatcccct tacaactaaa ttagtagtca tgtcctatcc gtccgattcg
   111241 acagaaacac ggggtagcgg attaatcttg gcttccagtc ctgcagcaaa aaaagcttac
   111301 ggcatcacca atatcagccg tgccagagat cttcccttcc cctatccaag tgatttatat
   111361 attgttgccc caaggatggc ctattatatg gaaaagaaca gagaaatcaa ttctatctat
   111421 aaaaaatatg cagacgaagc gaaccatcat gtctattccg tcgatgaaag cttccttgat
   111481 gtaacaaata gcatggcact ctttggtaaa acaaatgcgt acgacatggc taaactgatc
   111541 cataaagatg tgtttgagca gaccggaatc tacacgacta taggaattgg cgataacccg
   111601 ctacttgcta aactagcctt agacaatggc tcaaaagacg gaaagcaaat gtttgctgaa
   111661 tggcgttatg aagatgtacc agaaaagtta tggaaaatct cagatatcac tgacttttgg
   111721 ggaatcggca aacgaacagc aaaacgtctg aaacaaatgg gtatacattc tgtttatgat
   111781 ttagctcacg cggattatta tcacttgaaa agcaagctag gggtcatcgg tactcagctt
   111841 tatgcccatg cttggggcat cgatcgaagt tttttgggac aagaatatac accaaaatca
   111901 aaaagtatcg gaaatagtca aatcctagat agagattata caagacgaga agaaatcgag
   111961 atcgttatca aagaaatggc cgaccaagtc ggcactcgct tgagacgatc tgcagcaaaa
   112021 acacaagtag tcagcttatg ggtaggatac tctttaggct atcttgatcc aaatggcaag
   112081 accgggtttc accagcaaat gaaaatcgaa gcgacaaatg ctagcagaga tctagcagat
   112141 gctttattga ccattttcca ccagcattac cactaccagg atattcggcg tgtaggcgtg
   112201 aactgttccg acctcgtata cgcgacaggt ttacagctta acctttttga agatcctgaa
   112261 aagcagataa atgaagcgaa agttgatttt gttgtcgata cgattagaaa aaaatacggc
   112321 tttcaatcaa tcatccatgc gcatagtctc ttgcaaggag gacgcgccat cgcacgtagt
   112381 tctctcgttg gcgggcatgc aggtggtatg agtggattag aaggtggaaa agatgagacg
   112441 gacagcaaaa aaattcattg actataacga gtatcgagat cggccatttg gattaaaatg
   112501 ggggactgct tttgcgatgg aagaactagt caacggtatc aaaaaaaatg aagaagaagc
   112561 acgcaaacag cctcttccta aacaacaaat gacattgcaa gaaatcgata gtatactgac
   112621 agaagccttt ttatctcgta aagcagtaat cattcagctc aatttaaaag atgaatttgg
   112681 aagactcttg gatgaggtcg aagggcactt cattggtgaa gcctatgaag attactttat
   112741 gattgaccat cagccgatat tgtgggaaga cgtacggtat attgagttaa aggaaacaaa
   112801 aaaatggttt gtgacatgag aggttgtgac agaagtgatc aacttcaaaa aataagaaag
   112861 gatttttcga aaattgcttc ttaaattttt gtggaatttt ggcttatttt tcgaagaagc
   112921 aacttctgga acaacgtata ttagatatca gaggttgtga aaaagtcgct tagttttgag
   112981 taacaagcca aggcgctgat ttcacaacct ctgtctatct atccatctat tcggtaagat
   113041 tcatgcatga cgtcttcttt atttagtatg tagagccctt tttcttctga ccattcaaca
   113101 taaatcagct gttttacatc tgcatagcct tctttcttca agttctccat aagccatgct
   113161 tcagtcaatt gattggactg aagcacttta tgctgaattt gcccttcatc tacaagcagg
   113221 atcgataaag ctttgtcttc atctgatttt ttcaatacac tcatttgacc ggcattctct
   113281 aggataacat gtttggcatt ttcaagaaaa aagcattctt gctgtcttaa gattgctcgc
   113341 aactgctcca tctcgatatg gttatttgtc aactctgtca tgttgatgac gccgtctttg
   113401 attagaacag atggctcgcc tttgacccaa cgattgacct tttcattttt ttggacgata
   113461 cgttcgatac cataaatcat tactgcccaa agcgcaatgg caaataggac atgccctaca
   113521 tggacattgt catcataggt tgattcttct aagatcccac ctaaaacaag cgtatagact
   113581 aaatcaaacg gtgtgatttc tgacatggat ttcttcccaa gcaaacgtac cactaataat
   113641 aaaccgatca acccgaacac cagtttcatt gtaattgaaa aaatcatttt ttctccccct
   113701 aactatctgt taattaaatt atatatgctt tctcacgaac acgcatggaa tatacaagga
   113761 agaaatgtat ccttttacta aaaaaaggac tgtgacactg tagtgacccc caaaagttag
   113821 acttttttgg agtggagaaa tccactcctt ttttttatgc tctaaaatga tatttttaca
   113881 caaccgttac ggttgtttta cgaaattgga cgagactttg ccagtttaat ttctgtttta
   113941 tccgttcatt attgtagtaa tagatatagc tatcgatggc tgattttaat tcctcgaaac
   114001 agttataaac tttcccgtga aaaatctctt gttttaataa gccaaaaaaa ttctccataa
   114061 gtgaattatc taagcagttc cctttccgag acatgctttg aaagattttg tactccttca
   114121 atttgtttct ataagctttc atttgatacg cccaaccttg atctgagtga aacgtacgac
   114181 gatagggaca atcgttagtg gtctggatag cttcctccaa accttccatt accgctaatg
   114241 cattgggctt ttcagagata cgataggata aaatctcact attgaacata tccataaaag
   114301 gatctagata caatttcttt tgacggataa tgcctttggc atccacttca tggtatttaa
   114361 attcagttgt atccgtcgtg attttctgat ggcagatact ggtgtagaaa cgacgatgga
   114421 t
//
LOCUS       DAPBBV010000003       110876 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.003, whole genome shotgun sequence.
ACCESSION   DAPBBV010000003 DAPBBV010000000
VERSION     DAPBBV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 110876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 110876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..110876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.003"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..548)
                     /locus_tag="RD486_000269"
     CDS             complement(<1..548)
                     /locus_tag="RD486_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7662036.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAA"
     gene            complement(587..1705)
                     /locus_tag="RD486_000270"
     CDS             complement(587..1705)
                     /locus_tag="RD486_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HDT7662037.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(1702..3801)
                     /locus_tag="RD486_000271"
     CDS             complement(1702..3801)
                     /locus_tag="RD486_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HDT7662038.1"
                     /translation="MTINEVIYSPKHPLFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(3852..4673)
                     /locus_tag="RD486_000272"
     CDS             complement(3852..4673)
                     /locus_tag="RD486_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7662039.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLGCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(4670..5479)
                     /locus_tag="RD486_000273"
     CDS             complement(4670..5479)
                     /locus_tag="RD486_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7662040.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFVMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(5501..5995)
                     /locus_tag="RD486_000274"
     CDS             complement(5501..5995)
                     /locus_tag="RD486_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7662041.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(6007..6495)
                     /locus_tag="RD486_000275"
     CDS             complement(6007..6495)
                     /locus_tag="RD486_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7662042.1"
                     /translation="MFLKVGTGIAYMKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDYEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQEIKMTILDEVHVVNEEED
                     FF"
     gene            complement(6572..9268)
                     /locus_tag="RD486_000276"
     CDS             complement(6572..9268)
                     /locus_tag="RD486_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7662043.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKEYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLKHILSSEMKPVEFNRLIQELIKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKAEEPNYDMKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(9696..10769)
                     /locus_tag="RD486_000277"
     CDS             complement(9696..10769)
                     /locus_tag="RD486_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7662044.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(10766..11593)
                     /locus_tag="RD486_000278"
     CDS             complement(10766..11593)
                     /locus_tag="RD486_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662045.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(11594..12400)
                     /locus_tag="RD486_000279"
     CDS             complement(11594..12400)
                     /locus_tag="RD486_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662046.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(12412..13497)
                     /locus_tag="RD486_000280"
     CDS             complement(12412..13497)
                     /locus_tag="RD486_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662047.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(13514..14056)
                     /locus_tag="RD486_000281"
     CDS             complement(13514..14056)
                     /locus_tag="RD486_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7662048.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            14314..15303
                     /locus_tag="RD486_000282"
     CDS             14314..15303
                     /locus_tag="RD486_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDT7662049.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            15300..16037
                     /locus_tag="RD486_000283"
     CDS             15300..16037
                     /locus_tag="RD486_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HDT7662050.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            16034..16585
                     /gene="coaC"
                     /locus_tag="RD486_000284"
     CDS             16034..16585
                     /gene="coaC"
                     /locus_tag="RD486_000284"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HDT7662051.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            16601..17233
                     /locus_tag="RD486_000285"
     CDS             16601..17233
                     /locus_tag="RD486_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7662052.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            17318..17965
                     /locus_tag="RD486_000286"
     CDS             17318..17965
                     /locus_tag="RD486_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7662053.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            17970..18953
                     /locus_tag="RD486_000287"
     CDS             17970..18953
                     /locus_tag="RD486_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HDT7662054.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(19356..20870)
                     /locus_tag="RD486_000288"
     CDS             complement(19356..20870)
                     /locus_tag="RD486_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HDT7662055.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            21008..21814
                     /locus_tag="RD486_000289"
     CDS             21008..21814
                     /locus_tag="RD486_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662056.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(21989..22558)
                     /locus_tag="RD486_000290"
     CDS             complement(21989..22558)
                     /locus_tag="RD486_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662057.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(22641..24701)
                     /locus_tag="RD486_000291"
     CDS             complement(22641..24701)
                     /locus_tag="RD486_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HDT7662058.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(24978..26456)
                     /locus_tag="RD486_000292"
     CDS             complement(24978..26456)
                     /locus_tag="RD486_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7662059.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(26754..27689)
                     /gene="murB"
                     /locus_tag="RD486_000293"
     CDS             complement(26754..27689)
                     /gene="murB"
                     /locus_tag="RD486_000293"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDT7662060.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(27762..28682)
                     /locus_tag="RD486_000294"
     CDS             complement(27762..28682)
                     /locus_tag="RD486_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7662061.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            28795..29547
                     /gene="xth"
                     /locus_tag="RD486_000295"
     CDS             28795..29547
                     /gene="xth"
                     /locus_tag="RD486_000295"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDT7662062.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            30411..30944
                     /locus_tag="RD486_000296"
     CDS             30411..30944
                     /locus_tag="RD486_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HDT7662063.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(31434..31958)
                     /locus_tag="RD486_000297"
     CDS             complement(31434..31958)
                     /locus_tag="RD486_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662064.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(31951..32424)
                     /gene="tsaE"
                     /locus_tag="RD486_000298"
     CDS             complement(31951..32424)
                     /gene="tsaE"
                     /locus_tag="RD486_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDT7662065.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(32547..33527)
                     /gene="pta"
                     /locus_tag="RD486_000299"
     CDS             complement(32547..33527)
                     /gene="pta"
                     /locus_tag="RD486_000299"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDT7662066.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(33680..34360)
                     /locus_tag="RD486_000300"
     CDS             complement(33680..34360)
                     /locus_tag="RD486_000300"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDT7662067.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            34486..35355
                     /locus_tag="RD486_000301"
     CDS             34486..35355
                     /locus_tag="RD486_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7662068.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            35381..35896
                     /locus_tag="RD486_000302"
     CDS             35381..35896
                     /locus_tag="RD486_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662069.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(35943..36536)
                     /locus_tag="RD486_000303"
     CDS             complement(35943..36536)
                     /locus_tag="RD486_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662070.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(36561..36740)
                     /locus_tag="RD486_000304"
     CDS             complement(36561..36740)
                     /locus_tag="RD486_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662071.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(36817..37326)
                     /locus_tag="RD486_000305"
     CDS             complement(36817..37326)
                     /locus_tag="RD486_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662072.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(37422..37802)
                     /locus_tag="RD486_000306"
     CDS             complement(37422..37802)
                     /locus_tag="RD486_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7662073.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            38132..38881
                     /locus_tag="RD486_000307"
     CDS             38132..38881
                     /locus_tag="RD486_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HDT7662074.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(39065..40342)
                     /locus_tag="RD486_000308"
     CDS             complement(39065..40342)
                     /locus_tag="RD486_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662075.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(40421..41065)
                     /gene="pcp"
                     /locus_tag="RD486_000309"
     CDS             complement(40421..41065)
                     /gene="pcp"
                     /locus_tag="RD486_000309"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDT7662076.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(41264..42208)
                     /locus_tag="RD486_000310"
     CDS             complement(41264..42208)
                     /locus_tag="RD486_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDT7662077.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(42210..42896)
                     /locus_tag="RD486_000311"
     CDS             complement(42210..42896)
                     /locus_tag="RD486_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDT7662078.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            43369..43689
                     /locus_tag="RD486_000312"
     CDS             43369..43689
                     /locus_tag="RD486_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HDT7662079.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            43850..44755
                     /locus_tag="RD486_000313"
     CDS             43850..44755
                     /locus_tag="RD486_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7662080.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            44752..45525
                     /locus_tag="RD486_000314"
     CDS             44752..45525
                     /locus_tag="RD486_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7662081.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(45702..47126)
                     /locus_tag="RD486_000315"
     CDS             complement(45702..47126)
                     /locus_tag="RD486_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7662082.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            47337..47783
                     /gene="nrdI"
                     /locus_tag="RD486_000316"
     CDS             47337..47783
                     /gene="nrdI"
                     /locus_tag="RD486_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDT7662083.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            complement(47853..49835)
                     /locus_tag="RD486_000317"
     CDS             complement(47853..49835)
                     /locus_tag="RD486_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7662084.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(49849..50745)
                     /gene="murQ"
                     /locus_tag="RD486_000318"
     CDS             complement(49849..50745)
                     /gene="murQ"
                     /locus_tag="RD486_000318"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDT7662085.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            complement(50748..51809)
                     /locus_tag="RD486_000319"
     CDS             complement(50748..51809)
                     /locus_tag="RD486_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7662086.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(52021..52587)
                     /locus_tag="RD486_000320"
     CDS             complement(52021..52587)
                     /locus_tag="RD486_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7662087.1"
                     /translation="MVKENFVNEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQALAEKVVDLPVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELISYE"
     gene            complement(52615..54117)
                     /gene="eat(A)"
                     /locus_tag="RD486_000321"
     CDS             complement(52615..54117)
                     /gene="eat(A)"
                     /locus_tag="RD486_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDT7662088.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            complement(54375..55496)
                     /locus_tag="RD486_000322"
     CDS             complement(54375..55496)
                     /locus_tag="RD486_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7662089.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            55622..56563
                     /locus_tag="RD486_000323"
     CDS             55622..56563
                     /locus_tag="RD486_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDT7662090.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(56706..57602)
                     /locus_tag="RD486_000324"
     CDS             complement(56706..57602)
                     /locus_tag="RD486_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDT7662091.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            57884..59224
                     /locus_tag="RD486_000325"
     CDS             57884..59224
                     /locus_tag="RD486_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7662092.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            59419..59862
                     /locus_tag="RD486_000326"
     CDS             59419..59862
                     /locus_tag="RD486_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HDT7662093.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(60124..61542)
                     /gene="nhaC"
                     /locus_tag="RD486_000327"
     CDS             complement(60124..61542)
                     /gene="nhaC"
                     /locus_tag="RD486_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDT7662094.1"
                     /translation="MEKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKKYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDILEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(61946..63169)
                     /locus_tag="RD486_000328"
     CDS             complement(61946..63169)
                     /locus_tag="RD486_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDT7662095.1"
                     /translation="MTTTLSTNQLKDLIQYRLPEYQALALAIHDHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTGFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDEIGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDAALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAALSTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSEKGLASIAIAAELLANTALDLLREPKLLEKIKQE
                     HQEIVARKKQEGATF"
     gene            complement(63201..64040)
                     /locus_tag="RD486_000329"
     CDS             complement(63201..64040)
                     /locus_tag="RD486_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDT7662096.1"
                     /translation="MKKIIRFAVITFVAIIWLAGCSQGKAATTEKKETTVKLGIIGED
                     TDVWDDVKDRLKKENIHLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNEEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENKKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDEHARPYVNIIVARKEDEDNKTYQKIVDAYQTEETAKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(64057..64737)
                     /locus_tag="RD486_000330"
     CDS             complement(64057..64737)
                     /locus_tag="RD486_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662097.1"
                     /translation="MTEFFKTYLPNVYLIPDEFIEATKQTLYMSFWTAFIGGIIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILVLVFLSQFISN
                     QLIKKVTH"
     gene            complement(64739..65812)
                     /locus_tag="RD486_000331"
     CDS             complement(64739..65812)
                     /locus_tag="RD486_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7662098.1"
                     /translation="MIELRDISVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEAGK
                     IIEKGSSIQIFSHPEEELTKDFIRTATHLDQALETISAHAAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKVTILQKNELDNRIKVIEGGN"
     misc_binding    complement(65871..66109)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(66152..66385)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(66462..67133)
                     /locus_tag="RD486_000332"
     CDS             complement(66462..67133)
                     /locus_tag="RD486_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7662099.1"
                     /translation="MKGAIFDLDGLLVDTERTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KKWKQSFDILVQAAGSPEKVQEVRAKREEYFYQQLTSGAIQLKPYAKEILTDLKERHM
                     KLGIATTTVTKRATDILDHFQLADYFDTFTFGDEVSENKPSPVPYLTALERTGLEALS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYSVEEKEKLNLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(67221..69899)
                     /gene="mgtA"
                     /locus_tag="RD486_000333"
     CDS             complement(67221..69899)
                     /gene="mgtA"
                     /locus_tag="RD486_000333"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDT7662100.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASPNGLS
                     EEQIERSRETYGENAISYGKKTPFIIEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGEYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNDTLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEAAETLDTDTINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVAPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELITGEKISEMNDHELAQVAEEHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKIPFIQSNATFAMLVITTLGIIVGSVLPFTGFGAELGLM
                     PLPGNYWLWFFITVVAYLALVTAVKKIYIRRFQELL"
     gene            70559..70996
                     /gene="ndk"
                     /locus_tag="RD486_000334"
     CDS             70559..70996
                     /gene="ndk"
                     /locus_tag="RD486_000334"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDT7662101.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFATMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKGADAVPGTIR
                     GDYALPGTENIIHASDSRDAATKEIARFFPPFDTNKPSEKAAK"
     gene            complement(71018..71884)
                     /locus_tag="RD486_000335"
     CDS             complement(71018..71884)
                     /locus_tag="RD486_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7662102.1"
                     /translation="MYDGELIKKLRVNKKLTQTQLAEGICSKTSLVGIETNSVKKVSF
                     GTLKSFLERMNMTLAEYEWIRNQLDEPKKLKKKRRMLDRIQEDSFDPYKEIANNRRHY
                     KKTEDLYYLVLNLHMSKKTEVSETEFEFLRYECRIIEEYLMQVPEYGQFEVSILADFP
                     WIFSDRFIENNYLKIKKRMRRIAQLNNHEQYLFTFLTNLTLFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKSENHQEFFAVIEYTLGKNQRNSL
                     EKKLLAIAKPSS"
     gene            complement(72118..74196)
                     /locus_tag="RD486_000336"
     CDS             complement(72118..74196)
                     /locus_tag="RD486_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7662103.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPATLGQTEGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTIL
                     YPVTGTNAEQ"
     gene            74689..75906
                     /locus_tag="RD486_000337"
     CDS             74689..75906
                     /locus_tag="RD486_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDT7662104.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETREKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEASPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(76365..76988)
                     /locus_tag="RD486_000338"
     CDS             complement(76365..76988)
                     /locus_tag="RD486_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662105.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWEEYKLTANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLVVLLLTHDGDKVARLKNGKVVTAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     ASSQKNESTELSPSDSGSGQTITGNEENQASIITNESSEGQYQTYGQ"
     gene            complement(77144..78541)
                     /locus_tag="RD486_000339"
     CDS             complement(77144..78541)
                     /locus_tag="RD486_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7662106.1"
                     /translation="MKRYQFPKNFWWGSAASGPQTEGRISGDGKGENIFDYWYKNEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HHYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFQLFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKAYHEMDQSGVI
                     GIILNLTPSYPRDESNPEDVKAARIADAFFNRSFLDPAVKGEFPSELIERIKELDLMP
                     EIHPDDLTIIKENTVDLLGINYYQPRRIKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEKGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDRNGFEA"
     gene            complement(78563..79534)
                     /locus_tag="RD486_000340"
     CDS             complement(78563..79534)
                     /locus_tag="RD486_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7662107.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMEKISEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISNRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHAIDGLIVFLSEEEWSGFEMLTKMSIPVVALNCPGGPAGIDTIVVNDR
                     ESVAKVIAHHGGQGHKTIGFIAAAQTDYVARERLAGAKEAVQKDPSIHLEIFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            complement(79541..81841)
                     /locus_tag="RD486_000341"
     CDS             complement(79541..81841)
                     /locus_tag="RD486_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="HDT7662108.1"
                     /translation="MYDYPYQNPKLTIRQRVEDLLSRMNIAEKVGQVNQHLYGWECYE
                     KNGDKIELTEKLKEHVKWGGGLGALYGLFRSDPWSKTDYKNGIPAKESWKVANLVQEY
                     VLQHSRWKIPVLLVEECPHGHQGLDGISYPTNIGRGNTFNVALLEQSSRLMAKELAAK
                     GVHLALVSTLDLAKDPRWGRTEECFGEDPILSARFSEAVVRGFQGEIISEKVSFLDQT
                     VEEINKKKDQIGVVLKHCIAQGEALGGHNSGTVTIGRREFSDIYGPLLKSTRNAVGVM
                     AAYNDIDGIPCHINRALFEQTLRKEIGYQGIVMADGVALDRLSDVFTDKKTAAAYALA
                     AGIDLSLWDETYTKIAEAIDNQVVDEKLLDQAVRRVLSVKFLLGLFEQPFANDPKEYW
                     DHLMEESEHLNLETAKESITLLKNDGILPLDQQVKNIAVIGPNAHDVYHLLGDYSAPQ
                     TEDRLKKKIVQEIKTEFPQSKVSYAQGCEVRNQEDQEEKLLEAVTLAQNSDVIIAVLG
                     GSSARNFDMEFLRNGAVSSKGINMDSGENVDVASLSLGGYQEQLIEQLYQLGKPIITI
                     LVQGRPYDLMKIESFTNAIATAWFPGQEGGKAIAQMISGRNNPSGRLSLSYPRNSRQL
                     PVYYYQRAASKQENYYDLSGSPFYPFGHGLSYTTFEYSQMEVKTDIDKVIISIKVKNT
                     GSVSGKTSTLVYVRLIDGVVIQRTKLLKAFRKDELRSQEERLLVFELTSEDFSYMDID
                     DKRHYAKKAVIMVEQQEKEIKCNWQE"
     gene            complement(81843..83168)
                     /locus_tag="RD486_000342"
     CDS             complement(81843..83168)
                     /locus_tag="RD486_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7662109.1"
                     /translation="MKVVDRLSEKMLPIVSKMSSQRHLLAIRDSFIVTMPLVMAASVM
                     VLLNALIFSNATVQRILDLSPLAELASIVNNGTMSILAIIVCYNIGWNLATHYIQTGV
                     IDDPSFSPVHAGILSTAVMFILMSLSSTVTLMDGNTAEATGVFLQSLTSSSGLATAMI
                     AALVSTELFIKLAKMKSFKIRMPEGVPPAVAASFNSLVPEIVVILFFSVVVFTLNHTT
                     GLNVPQLIELAIQTPLKAFVLSVPGILFLQFFSDFLWVFGMHGSSILAPIRQAPLLQS
                     IQENMDAFSVGKEIPNIITEPFTNAFGLIGGGGCILPLVIAILWASKRQEQRSIAKFG
                     LTTCLFNITEPIMFGLPVVMNPIYMIPCAIIPSINLVIAYAATSLGIISKTVAAAPWI
                     TPPVIQSFIATGGDIRAAVLTVILIILDVFLFLPFVLAANKAKLAEGGY"
     gene            83399..83824
                     /locus_tag="RD486_000343"
     CDS             83399..83824
                     /locus_tag="RD486_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662110.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGADSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATVTFTKIGNYRLKDKDGNIYSL"
     gene            complement(84322..85023)
                     /locus_tag="RD486_000344"
     CDS             complement(84322..85023)
                     /locus_tag="RD486_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7662111.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDTFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(85039..85479)
                     /locus_tag="RD486_000345"
     CDS             complement(85039..85479)
                     /locus_tag="RD486_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HDT7662112.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTITSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVLAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFEKLPVETYVGEYL"
     gene            complement(85479..86054)
                     /locus_tag="RD486_000346"
     CDS             complement(85479..86054)
                     /locus_tag="RD486_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HDT7662113.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(86465..86944)
                     /locus_tag="RD486_000347"
     CDS             complement(86465..86944)
                     /locus_tag="RD486_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HDT7662114.1"
                     /translation="MFLDSGVVLKETELERIEYTDFGLGAIETEGLNLFVYENNERYC
                     GKELVLLPYQTCPEHRHPPRDENEGKKETFRCRKGLVYLYVEGKETKKLSCIIPKGQE
                     RYYTAKKEIILHAGDQYTIEQNIKHWFQAGATGAVITEFSSSSDDPSDSFTNPAIYR"
     gene            complement(86982..87461)
                     /locus_tag="RD486_000348"
                     /pseudo
     CDS             complement(86982..87461)
                     /locus_tag="RD486_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(87633..88334)
                     /locus_tag="RD486_000349"
     CDS             complement(87633..88334)
                     /locus_tag="RD486_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7662115.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQEILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(88442..89884)
                     /locus_tag="RD486_000350"
     CDS             complement(88442..89884)
                     /locus_tag="RD486_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7662116.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCMDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            complement(89898..91763)
                     /locus_tag="RD486_000351"
     CDS             complement(89898..91763)
                     /locus_tag="RD486_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7662117.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(91884..92735)
                     /locus_tag="RD486_000352"
     CDS             complement(91884..92735)
                     /locus_tag="RD486_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7662118.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(93045..93758)
                     /locus_tag="RD486_000353"
     CDS             complement(93045..93758)
                     /locus_tag="RD486_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDT7662119.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(93826..94152)
                     /locus_tag="RD486_000354"
     CDS             complement(93826..94152)
                     /locus_tag="RD486_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDT7662120.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(94275..94538)
                     /locus_tag="RD486_000355"
     CDS             complement(94275..94538)
                     /locus_tag="RD486_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDT7662121.1"
                     /translation="MEKQANPYDHKKMLTQQLRELEQDESIHRKAYNQVPPKVEYSLT
                     EEGKSLREILVALSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(94823..96076)
                     /locus_tag="RD486_000356"
     CDS             complement(94823..96076)
                     /locus_tag="RD486_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7662122.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            96137..96877
                     /locus_tag="RD486_000357"
     CDS             96137..96877
                     /locus_tag="RD486_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7662123.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(96963..97721)
                     /locus_tag="RD486_000358"
     CDS             complement(96963..97721)
                     /locus_tag="RD486_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDT7662124.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(97718..98746)
                     /locus_tag="RD486_000359"
                     /pseudo
     CDS             complement(97718..98746)
                     /locus_tag="RD486_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(98793..101933)
                     /locus_tag="RD486_000360"
     CDS             complement(98793..101933)
                     /locus_tag="RD486_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662125.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEIT"
     gene            complement(102157..103041)
                     /locus_tag="RD486_000361"
     CDS             complement(102157..103041)
                     /locus_tag="RD486_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDT7662126.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(103136..103573)
                     /locus_tag="RD486_000362"
     CDS             complement(103136..103573)
                     /locus_tag="RD486_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662127.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(103790..104701)
                     /locus_tag="RD486_000363"
     CDS             complement(103790..104701)
                     /locus_tag="RD486_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDT7662128.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(105158..105586)
                     /locus_tag="RD486_000364"
     CDS             complement(105158..105586)
                     /locus_tag="RD486_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662129.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(105614..106252)
                     /locus_tag="RD486_000365"
     CDS             complement(105614..106252)
                     /locus_tag="RD486_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662130.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(106256..108238)
                     /locus_tag="RD486_000366"
     CDS             complement(106256..108238)
                     /locus_tag="RD486_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDT7662131.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            108418..109083
                     /locus_tag="RD486_000367"
     CDS             108418..109083
                     /locus_tag="RD486_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7662132.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(110574..>110876)
                     /locus_tag="RD486_000368"
     CDS             complement(110574..>110876)
                     /locus_tag="RD486_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7662133.1"
                     /translation="LGVKGQNLLADDSFWQIEAFYLAQCAYNTTLMLSPDRIIFGGGV
                     MKQEHMKKKVQDKFVELINGYVEIPPIASYIVTPELGDSAGIIGGLALARKAIRNK"
BASE COUNT        32488 a        23178 c        19024 g        36186 t
ORIGIN      
        1 gctgccatcc cctctaaaca atcttggtgg aagggacagt ttcctgaaaa attgtccttt
       61 ggatgtcgct tgatcaacat atgccccatt tccggatgac tgaacccttc cacgaaagtc
      121 ccattgaaca aggcaccacc tccgatacct gttcccacag tgaagtatgc aacacctgct
      181 aaccctttgc cagaaccagc aacatattca ccatagcaag ccgcattgac atctgttgtc
      241 cattcaatcg gaatattgaa atattgcttt agcgttccta caaaattgaa attttgccaa
      301 gcaagttttg gtgttgatgt gatatgaccg aaactcgttg atttgcattg aatatcaatt
      361 ggaccaaagc agccgacccc gatgcctgcc aattgttcct taaaaggttt aaaaaaatca
      421 atgacctgct tcattgtttc aactggagtt gttgtgggaa aactgactct ttccaaaatc
      481 gttaattcct cagtaccgac tgcacagaca aatttagtcc ctccagcttc aattgcccca
      541 tatatcatca taggttcctc ccttcgaata tgtgaaaaac acttcattaa cgcggcaagc
      601 gttctcgatc agtgaaatga cgtttagtat ttcctgaagc ttctgttgaa taccagtaag
      661 cgacactagc aacatcgtct tgccgctcaa ataagcgaac atcatcgttg ccgatttgtt
      721 gtaaagtgac cgataaatct tcggtaaaac agatggggtc ttgaagatgc caacgataaa
      781 gaccatgtcg tggcattgcg tcgtcaccaa aggcatgaac ggcattcaat tttcccgttt
      841 caaaacgatc tcttgtggca tctctatttg attggtaagg ataccctaaa aaggctgttg
      901 aatagttttt cgcatgtgga cgtccgaact catcgtactc atgaaaggcc cacgccccgc
      961 caaaataatc ttctgaacct gttgaggtta cggtcggata ctcactatcc ccatcaatgt
     1021 agaatttaaa ctcgccttcg ccccaccaat aacgttctag gcaggtaagc gcaaggtaag
     1081 tacccacgta atagccttga ccctttaatc gatcaattaa cttataatcc tcctgtaatt
     1141 tggtaatgcg ttcccgatgc caatttgcgt gaaaatatag gctattttct tccaattcgt
     1201 ccaccaaagc gtaatttatc gtataaaaaa atgaggacat atccttcgga tgtaaattct
     1261 cgatcgtaat tttagcggat gtttggaaag gcatttcgaa ataggaatta aagccccctg
     1321 taggattaac cactatcggc aacgagttca cctcgcaacg ctctccaaac ccattacaaa
     1381 agaaatcccc taaaggactt tcaacagcag ggctatccga cccatcccaa taaattctta
     1441 agattaaatc acgtaaaaca aaactgccaa attctgttcg atcacgaatc gtcatccaca
     1501 tatgacgaat tattcccgtt ccagtaatat ccgcaatcac agtttcttca ccagaagtca
     1561 gcggaattgc gccacgacct ttgcggcttg gtcctagctc gcttggcaac atcgcagctt
     1621 tacctttctc gcctgttgga ttttcgggag tgattgctcg actctggatt tttttaaatt
     1681 gggtaatatt ttttagtata ctcatctttt tctcctttga atgtgaatcg tttttccctt
     1741 ttctacgtga agaatttttt tcgtatcact tattttcaat ggcttttctg acaaatttga
     1801 aatactcaac tcggattgcg tacattcaat cgaaatgaag gcttgaccga acttcaaatt
     1861 cttccaagaa aacgttaaat tatcaacagg atcaatttgc aatactcctt ttttgaattt
     1921 caatccgaaa tattgactga tcattaggct gacaaaaaga cccgatgccc agccgcattt
     1981 gccgcagcca aagtctcgca cgacttctcc ttgttgagcc tctaagcgat acggccacca
     2041 ccaccacgaa ccgtctaaat ctgccaaaca aattagttct tctaatcggg ttacgaaagc
     2101 ttgagggttg tgcagctcgc tcattaaaac agtgataaag ccaggaaaag tggcgccgga
     2161 ttctaatccc caagtgatgc ctttgatttc ctcgctatag gttggattga aagaactagc
     2221 agaaaaggcc atggtgttct gatataaatg atctttatta tctaaaaatt gataaaaagg
     2281 catcaacgta gtgtctgatt cttctccatc atgcatcaat aaattaattt ttccatccac
     2341 aatcacatca cttaaaaaga ttaacccttg ctcaagaatc ggtttttgat agtgcttcac
     2401 tgaataggtt gttttctcct catcaccgat tccctccaaa aattgctcac caaaaggacc
     2461 atcgatagtc atttgtttac aaattgattc ctttagttta caggcaatgt ttttgtatcg
     2521 cttgctaaga ctcagttgtt ctagggcttc aaaaatttct gcaagtccaa tacaggcctt
     2581 ccaaagacaa agattgctgc cggtatgata ctttccaagt gcaaaggcgt ctgataacca
     2641 aacagatgga aaaagcattg gttcccctga ccgacgttga gctaatatgt cctcaataat
     2701 tcttgaagca ttcagtagaa cctgcggaca ccgctcaaag aattttgtat ccccagtatg
     2761 ttcaaaataa agactagcca gtaacgcact ggataacgaa ttactcagag aatgattgat
     2821 acctcctgta aattttgaac caggaaactt aacgccatat tgatcaaacc atagaaccgt
     2881 tttttgacat aactccggtt caaacatggt gaatggcaat gatgcgtaat acatatcctt
     2941 attccaaatt cgattagtag caggatagct gccccaattg ctgccgacga cctgtccctg
     3001 tcgattcata ccgaaactag aaaagctttg ataaagtgca cgacgataga gatggacaac
     3061 tctatcgttt ggcattgaca gctgcccaaa tagctgagca aaatagttca atgtttcctt
     3121 cagccatttt tcgatatcag attcctgaaa agtcattact tcttcaaaag catttgggtc
     3181 cacaaaagca atggcgaagc ttgccacttc ctgttgtgcg atcgtgtcct tatttccttt
     3241 ttgagaaatc aacacatttt gctgatccga atacttctct tgatacgaag gcacatcttt
     3301 cactgaaact tgaaggcttt cgtgtgtttc attcacaatg taaacctgtt gaacaagcat
     3361 acttaaacgc ttattagcca gtatgggagc aaaggatact acaatgacct taaacgtcga
     3421 ataatgatga atatatctag gcaaacagtc ttgaatcaca tcgacttcaa tacgatgatc
     3481 cgattctgac aaatggtaga caatcccgtt tacttcaacc tttaaggata acgaattggt
     3541 ttgagagagc tgtttattga cccaaacacc tggtttttcc tcagttagta aattttctcg
     3601 ataaaaggtc aacgtttgaa tcgtcccgca aacatcaagg tttgctaatg tcttttgatt
     3661 acttacatcg aaggtcaatc cctttacatc aggaatattc cgatagtagc tgtattcgtt
     3721 tgaagtagtc acatttccgt cgtttaactc agcattaaat aatgggtgtt tgggtgaata
     3781 aattacttca ttaatagtca tcttttccct ccttgctaaa aaaactgcag cctagtagct
     3841 gcagcttcct actatgcgat tccaagtaat gacaataaaa ttcccaagac gaccattcca
     3901 aaaataattt tgatgacgcc gactttttta tctagtaatt tgaaacagcc caatgttacc
     3961 aataacggta caattccttt aaaaatacta tcgaggattt cttggacatt cattagttct
     4021 tcgcccttca ttgaaaagct caaaacggta ttgaatttga ccatactgat cgtcattgcg
     4081 cctaccatga tcagacccaa gatactagca gcttttgtca gaatttcaat taacccgttc
     4141 gcatacagct tttcaatata tttagagcct aatgaatagc ctaaaacgcc gccatagtat
     4201 cgcatcaaat aattaggtat attgaacata actaaaaaga taattggtgc caaaatattt
     4261 ccggcattgg ctaagttgat cgctagtccc gcggtaacga cacgccaaac tccccagaac
     4321 aatgaatcgc caattccagc caatggtccc atcaaactcg ttttgatcgc gttgatactt
     4381 tccacgtcaa aaccagcttt ttcagaattt tccttctcca tcgatgccgc aatccccatg
     4441 acaaaggacg cgcaaggaat ggtcgtcgaa aaatactgtg tatgacgttc cagcgccgca
     4501 gctcgatctt cttcactttt gtagaaatga ttaatgaagg gcatcataga ataggcgaaa
     4561 ccaccgccgc ccatcgtcac cggattcacc gaagcataca tagtcatcga gcgccaaaac
     4621 atcttccgaa ccaatttttt ctcatcttta gaaattccat cagctaattt cattgaaaga
     4681 aatcctcctc ttcttggtca agcgttgcat ttacagcagc atcgctttga actgcatgaa
     4741 cagatatatt ttttagttgt agatctcttt gggctataac aattgcaata atcgttccaa
     4801 ctgcggcaat tgcaatcaat ggtaactcga gatacgccat aacaacggcc ccaaagaaaa
     4861 accacacagc aatattttta ctccaaagca tccgtaacag catagccatc ccaactgccg
     4921 gcagcagatt tccagcgact gttaatccgt tcatgatgac ctctggaata ttatccaaga
     4981 cgcttttgac aacatctgct ccaaataaaa cggcaaagaa tggaataaga gcataaagcg
     5041 catagtggac aaaccacata acgaagtgca gattgatgat tcctttttga tcaccagatt
     5101 ttgcaaattt gaaaaattta gcagccatcg gtccacatac aaaagaaaaa atcatattca
     5161 ttaactgtaa tcctaatact gctagtggaa agacaatggg aataatcgca tccacgtttc
     5221 ctcccatttt gattgcgaac gctgtagcca acccagcagc caaagaaggc tccgccgtac
     5281 tagagattcc gatattgacg acacccataa aaatggcttc tagtgacgcc ccgacaatca
     5341 accccgtctg caaatccccc atcaacgctc ctgctaacgg agcaacaaca atcggacgac
     5401 tcagcatgga catcccgaac atttcatgtc cagcaactcc aataaaaacg gccaaagcga
     5461 ctacaaatgc atcatacata atttttctcc ttcctttttt ctaaaaatca ctcaaaatag
     5521 agatagctga acgtttttcc atcgccggtg taggctgaaa aacggtatct ggataaagtt
     5581 caactaattc ttttaagtct tgaatttctg acgtcgttaa catcacttcc tttgataagg
     5641 ttttcttatc ttccgatggc ggtgtcattt tcccagcatt ccccacgttc attaattcga
     5701 tttccgttgg gaaagctttc gcaactttta ccgcatcttt gacattaggg actaaaacca
     5761 tcaagcgcat gtccttcgcc cgcggatctt ttaacaaatg aatcgcgtca tcaactgttt
     5821 taataatgac tttgacattc gatggtgcag ccatcttcaa tgtcatcttt tgaatatcgt
     5881 tggtagccgc ctcatcgctg gctactacta acccggttaa atttagactc tttgtccaag
     5941 tcatcgctac ttgtccatga attaatcgtt catcaattcg cactgcttta atcatttttc
     6001 ttcctcctaa aaaaaatctt cctcttcatt tactacatgt acctcatcaa gaatggtcat
     6061 ctttatttcc tgttggcatt tatttaccag ttcctgaata tcctcctttg ttaattcctt
     6121 ggttgccaat actatttcga gcagaattgg cagattaaag ccagacaaaa tagttacagc
     6181 aatctctttc tccaaaaagg ttttggtaat cttctgattg acacttccgc caaataaatc
     6241 ggtaaaaaca aaaatctgat cctgctcgtt cacctggttt acaaatacat tcaactcctg
     6301 ttcataatca cactcatcca cataagcatt aatcaccgta atctcttgaa ccttccccgt
     6361 cagtaattga atactgctaa gaaagcctga agctaagtga ccgtgagtcg ctattagaat
     6421 tttcttcata tggttaattc ctttctttct gttcactttc atataagcaa ttcctgtgcc
     6481 aacttttaaa aacattggtt taatcacgtt aattcacata aaaaaaagtg tctaacctga
     6541 aaaaatcaga ttagacactt ttttagacac tttatttttg aatatacggt cctaataatt
     6601 catagagcag cgaaagctca taagcattga ctttaaaatt atatttcatc tccattgatt
     6661 gaaaaatact tctcgaaaca taataaaatt catcttcatc tggtttcata tcataatttg
     6721 gttcttctgc tttttctgtc cgcgccaaga ataaacgttc catcatcaat gccgtatgca
     6781 tataaagatt tagttttacg cggccattta aagtgaaatg atagtaattt tcatatttag
     6841 aaatgactgt ttccacctca ctcatcacga ttgttgggtt cagaaagttc aaacggtctg
     6901 cgattccttc caatgaaaag aattttatca gctcctgaat caaacggtta aattctaccg
     6961 gcttcatctc agaactcaaa atatgcttca aattggctgc tccatcacca tctaaaatat
     7021 catatacatt gatattagga attgaaaagg aacgtggaag atccgaagtc gtgatgacca
     7081 attttgtctt gtcaaaataa gtttcatcat tttggtcgat taattcacgt agttctctgt
     7141 attccttcgt gaaaacttcg atggactcat ccgataaatg atgacgaaaa acatccttca
     7201 gtttatccga gatacccaat cccgacatgc aggaaatgat gatgttgcta ctttgagaaa
     7261 agccttcaaa gtattgaaca ttgattgaat acttgtctgc tgcatcctcc gcaatctgtt
     7321 taaatggcgc attcatcgtc atcttcaagc caatatcaag tgcaatggaa gtcgtcaaat
     7381 tattcagaag aagtaactcc ccttttaaat cgttcttgat ctgtgtgtaa atttgattta
     7441 aagagcccat atctacgatc agcactagac tatctgtatt cacttgccgt ttcacgaaat
     7501 tccttgtcga ttcgacaatc tctgacacat tactctctac tggcatatcc aacgcttcaa
     7561 aaacataatt gccgcataat tgattcacta ctgcttgaat gctgctagcc gtactatctc
     7621 cgtgagcaag caacaggccc ttcagctcga tggattcatc tacataatca gataaagtca
     7681 cgacaataag cagtcttaga aagttctcgt ccttttctga gagcggtggt aaatgctcca
     7741 agaactgatt acataagtaa gtcgtccgag gtagatttgc agctaatgta cgatttatcc
     7801 cggttaagtc tgtcttatag cttggggaaa tgacatagga tctgctaata atttctgcaa
     7861 caggtccact cgtcgtcaat ccgtacgttt ttcctaaaac ggatacccag acctttctaa
     7921 acatctgaat catcaatttt ctactcattg ataaaaaaga atccttatca atgtgatgca
     7981 ccaaatgctg tacttcattc tttatcgaag aaaaattttc attgaaatta ccttcattta
     8041 tcagctgagt aattttttcc aaaatcgaat cataatcaaa cggtttgatt cgatccgttt
     8101 ttatcttttg atttttcttt atcaataaac tagcaatcgg caagctttct acttcggatt
     8161 ccagcatatt taactgaatc aagatctcat ttttcccaat cgttaatggt tcttcttgtg
     8221 ttcgactata cacatccgca caactgattt taatgatatt cttcagctta ccaatattcc
     8281 cactaaaggg atgagataac attaaagaca aggcttctct tgaaacaata atatcttttt
     8341 gtaaaacatc cgcttcattt tgaaaaaata attgaatcag ctctaatcgt tctcgaatgg
     8401 ggcgatcttc aaaagttggc aacataacac taatttgaat acgccgatca aaggtgtcta
     8461 ataaataatt ttcacctttt tccgtcgtgg cgaaaataaa acgaacctta gcagaatgcc
     8521 aatttacatt ttcaccgact ggacgatagt ttccagtatc aataaataga aagagctttt
     8581 cttgattttc tttcgatagg cgatggacct catcgagaaa aagatagccg ttgttggccg
     8641 ttgccaataa accatcggta tccttttcag cccccgtaaa ggcccccttc ttgtatccaa
     8701 acagtgttgc cgaaagcagt tcgggattgt ccgcataatc ggcacagttt aagatagcaa
     8761 atggtgcatc tttttcaata atttgctcat ggatagcgta ttcaaaaatt tttgtggcta
     8821 aaaaactttt tccaacaccc gtggctccat ttattaatac actgagtccg ttaggcggat
     8881 atttgacagc ggctatacat ttttgaatga cctctctcag acttccgtca tgaccaacta
     8941 cagaatgaaa ggcttcgttt atttgctccg tattatctac aaccgcatat tcatctaaag
     9001 gcttccacaa aacaggcttt cccggtaatt tctcgacctt tttatcttcc actaatctcg
     9061 tcaaataatg gctggcattc tgacgagaga tacctagatt cttcgaaatt ttctcggcag
     9121 tgacagaaga catattccct gttagtcgta tcagctcatc aaaaactcga tctttagcgc
     9181 tctttttcat tttttcctcc agtttaatgt gtctaaaagc ataataaact atcggctgca
     9241 atatgtctat tctatatttg tattccaatt tttactttga aacacaaata gtcgaatatt
     9301 tgcctcagat atctgacaaa ataatttatc taccaattta gtttttatct aatatgattt
     9361 ttatgttttt tcatagctac aaatattgaa ctggattcat atattagttt tattaataga
     9421 ttacagaagg gttaagtata tttgcatagt ttccaattac tttatccttc tgtaactttt
     9481 tcaatcttag atttactagc ccgtctcggg ccctatttta caatggtttt gtccactttt
     9541 ctctggtaga aaaacgtggt agaaaaaata aaataacaca aaaaaagcgg cgtttcatcc
     9601 gcttttggta gaagattgga aaactcagat agaaaaagga cgatttttag ctctttagaa
     9661 cgttgataag tccccattct tactgagttt tgccattatc tcctatacat cttgaattct
     9721 aagaataggt cattatagat gcctaggtat ttcgatccta gatctttgta gacttcaaga
     9781 tgggagatcg tgtcatcaga tggatagaat tgttcgtccg acgaaatgtc ttttggcaat
     9841 aacgcttttg cttcttcatt tggtgtagaa taaccaatat actctgcatt ttgtgccgca
     9901 ttttccggtt ctagcataaa gttgatgaaa tcataggcac cttctttatt tttcacggtt
     9961 tttggcataa cgatattatc aaaccaaaga ttggatcctt ctggtgggat cacataatgt
    10021 aaatgttcat tttcccacat catatcggca gcttcgccag aaaatgtcac tgccacggag
    10081 gcttcttcat tgatcatata cattttgatc tcatctgcca cgattgcttt gacatttggt
    10141 gttaaatgat tcaatttatt tgctgcttct gtcagctgtg ccatattctt actattcaaa
    10201 gaatagccta aactattcaa agaaagcccc ataacttctc gtgcaccgtc aatcagcatc
    10261 aaactgtctt ttaattccgg cttccacaaa tcatcccaat gcttaatttg atttgcatca
    10321 aagaatttat cgttatatac gatccctaaa gttccccaaa aatatggaat cgaatactga
    10381 ttatctggat caaaatccaa gtctaaaaat cgtggatcaa tattatttaa tcctttgatc
    10441 ttcgaatgat ctaatggaag tactagtttt tctttgatca ttttttggat catatattca
    10501 cttggtatag cgatgtcgta gtttgtccca ccttgctgga tttttgtgaa catcgcttca
    10561 ttagaatcaa atgtttcata attcactttg tatccatatt ctttttcaaa tttcgtgatc
    10621 aaactaggat cgatataatc tccccagtta tagatggtaa gtacctttgc tccactcatg
    10681 ccacttgttt tttcaagttg acgaacacca agcagcagca ccgcaataat gatgagaata
    10741 cctaaaaaca gagattgtaa ttttttcatc gcagccgtgc caccccctcg cgtactcttc
    10801 tgtttttctt cagccgtttt ggacggtttt ctttactaat aaagtagtat ccaatgacca
    10861 atatcatgga gaacaagaaa actaacgcac ttagcgcatt gatttctaaa ctgattcctt
    10921 gtcttgcacg agaatagatc tctactgaga gcgtcgtaaa gccatttcct gtgacgaaaa
    10981 atgtaaccgc aaaatcatca agagaatagg taaatgccat aaaatatcca gctatgattc
    11041 ctggagaaag ataaggcaaa atgatatttt tgactacttg gaaattatta gcaccaaggt
    11101 ctctagccgc atcgaccatt gaatcgttca tttcctgcaa ttttggcaag accatcaaga
    11161 cgacgattgg aatgctgaaa gcaatatggg aaagcaatac actctgaaaa cctaatccga
    11221 atcctagtag tgtaaagaaa atcaagaaac tagcaccgat aataacatca ggagagacta
    11281 ataagatgtt attcatgctc aacaacgctg tccgtgcacg tcgttttttc gtgtaataga
    11341 ttcccatagc cccaaatgtc ccgatgatcg tggcgatcaa tgcagataag aaagccagca
    11401 tgaacgtatt caatacgata atgatcaaac gtgtatcttc aaaaacagct tcataatttt
    11461 cccaagtaaa tcctgtaaag ctgttcatcg ttcctccttc attgaaggaa taaaaaatca
    11521 gatagaagat cggtgcatat aagaataaaa agacgatccc taaataaaga tacgaccatt
    11581 taaatttttt catttatgag cgacctcctt ttttcttctc gcctgtcagg agcatcacga
    11641 tgaacatagc aatgattaaa atcacaccga ttgtagaacc catcccccag ttttgtgtaa
    11701 ccaagaaatg ctgttcgata gccgttccta aagtgatcac ccgatttccg ccaatcagac
    11761 gagtcagcat gaataaagaa agagaaggaa taaatactgc ttggacacca cttttcacac
    11821 catttaatga taacggaaaa atcactcgtc ggaaggtctc aaagctattc gcgcctaaat
    11881 ctctactagc actgatcaaa gaaggattca tctcttccaa tgcattgaaa attggcataa
    11941 tcataaatgg aatctcgata tacgttgcca cgaacagaaa actgaagtct gtgaataata
    12001 tctgtttcgg cccgatcccg ataaaatcaa agaaatgatt cacgctgccg tgcacactga
    12061 aaatcccaat aaatgcgtaa gctttaagca gcagattcac ccatgtaggc aaaataatca
    12121 gcatcagcca taattgcttg tgcttcagtt ttgttaaaaa ataagcagtc gggtaactga
    12181 tgatcagcgt gaaaaacgtg atcaaaaatg cataccatac agaattgatc gtcatagaaa
    12241 gcgatgtccc cgacgtaaaa taagatagat aattattcag cgtgaattgc ccattcatat
    12301 caaaaaaaga ttgataaatg atcattaata caggcgcgat cacgaataaa ccgagccaca
    12361 aaatataagg gacggaatag atcctgcgca ttgttttcat tcttgtcccc cctattcttc
    12421 gtagctgtca agacgtgcat cgaattcttc ttcagactcg ttgaaacgca tgacatggat
    12481 atcttctggc tcaaaggcca atcctacttt gcttccttct ttagcttttt tcgttgaatg
    12541 gaccatccat tcattttgct gttcatcata acagatgatt tcataatgga caccacgaaa
    12601 cagctgagta tcgaccgtta cgactagttt tcctttatct ggtgtcgtga tcgtcaaatc
    12661 ctctgggcgt aaaacaactt caactggttc atttagacgc atcccgccat cgacacattc
    12721 aaattgctta ccaacaaact caactagatt atcttcgatc attacaccgt ccacgatatt
    12781 gctctcccca acaaaatcag caacgaaatg attgattggc tcatcataaa tatctacggg
    12841 tgtaccactt tggacgattt tccctttatt catgacaaaa atctcatcac tcattgccaa
    12901 cgcttcttct tggtcatgag taacaaaaat aaacgtgatt cctaatcgtt gttgcagatc
    12961 ccgcagttca tactgcatat ctgtacgtag tttcaaatca agcgccgata acggttcatc
    13021 taatagcaat actttcggtt catttacaat tgctcgtgca atcgctacac gctgtctttg
    13081 accaccagac atttcactaa tctcccgttt ttcgtatcca ggaagctgga ccatacgcaa
    13141 agcatctttt accttctttt cgatatctga tttggacatt ttcttgatct tcaatccaaa
    13201 agcaacgtta tcaaaaacat tcatatgagg aaaaagtgca taatcttgga agactgtatt
    13261 tacttgtcgc ttattagctg gcaaatcatt caaccgtttc ccttcaaaat agatgtcccc
    13321 ttctgtagct tcggtgaatc cagctataat acgtaggatc gttgttttac cacagccgga
    13381 aggaccaagc agtgtataaa attttccttg ttcgatctca aaacttactt tttttaatac
    13441 tgtttcatca tcatagcgtt tcactacttg atcaaatgaa atgattggtt tccccacgtt
    13501 tttaccccct atattacaaa tatgattgcg ttgcaacaat caatactttt gttcgttttt
    13561 tgagatgatt ccttaattga tgttgttttg tcgcttgata atagatcgac tgtcctgctt
    13621 ttgccacata gaccgtctct cctaagctta actctaattc cccttctaat acaaaaataa
    13681 acgtttcaga taatgaaggt tcaaacgtct tatattctcc tgcaccttca aaagtcagca
    13741 agacaggctc catttctttt tcattcgaat cagccacgag ccattccaat tcatacccgt
    13801 tttcttcatc gaaataaacc gtatgatctt cttttgaata aaccacttgc agattcgctg
    13861 cttcttgatg aaaaaattct tctggagtca cacctaagac ttcaagaata gaaaagaatg
    13921 tttccattga tggtgaactt aaatctcgtt ccaactggga aatataccct tttgacaaat
    13981 ctgtgcgttc gcctagttct tcttgtgtca aattcttttg gatgcgcaaa tttcttaact
    14041 tctcaccaat ttccataatt tcctccgaat cgaagttttc taatagtaaa cttcctgttt
    14101 actaccactc gtattagtat acgaaattta ttgaaaaagg caaccctttg taaaattttt
    14161 tttgctgaat atttctttat cttttggaat aaattctagt tgtttgattc tttatttttc
    14221 acctaatttt tgtctaaatt tacggaagaa caagaataaa agagtaggct ttatggtatg
    14281 ataaaagaaa attttaaaag gagtgtctca cgaatgaacg cttttcgatc ttttcaggta
    14341 ataaaggaac ctgttttcca tacagcaatc agtgatctgc catttactga gttggctgaa
    14401 aatgaagtct tggtaaaaat tgcctattct gatgtcaatt ataaagatgc attggcaatg
    14461 agcgagtctg gtcaggtgat acgaacatat ccgatgactc cagggattga tttatccgga
    14521 actgtcgtcc aaagtaacaa tccacgtttt tcaaaagaag atcttgtact tgctactggt
    14581 tttgggcttg gcgtcaccca tccaggcggt tatagccaat atcaaaaagt accaggagac
    14641 tggttagttc ctctaccaaa aaatatgacg ctgcgtcaag cgatgatcct tggtacagca
    14701 gggtttactg ctatgttgtg tgtgaacgct ttaatccgtc aaggtatgac ctccgataaa
    14761 aaagttgtcg ttactggtgc ttctggcggt gtaggcagta cagcgatagc cctgttacat
    14821 aaactaggat tccagtcaat cattgccttt tccagaaaag aagagtctgt cacatggcta
    14881 aaaagtctag gtgctttgca agtcgtacga cctgatgaat ttctgccaga gacaacaaaa
    14941 gctttaggaa aacagcaaat cgactatgtc atcgacacag taggtggcga gcagctaagc
    15001 agtcttcttc cattgatctc ttataacggt gcagtagctt tatgtggcaa tgctggggga
    15061 atcaaactaa acgcgactgt cttgcctttt attctgcgaa acatccagtt gattggaatt
    15121 gattctgtca atgtaccaat agatcaacgt ctttctttat ggcaacagat ggcggatttg
    15181 cagattgcag atgaactggt cgtccaagag attactctgg atcaattgcc tgaaacagca
    15241 tctaaactac ttgctggaac acaccaagga agaacactag taaatgtagg tgaccataaa
    15301 tgaagattct aatcacagct ggaggaacga ctgaaaaaat cgatcaagta cgtgctatta
    15361 caaatcattc gacaggacga ttagggcaag cattagctga ttatttagct gccaatccgg
    15421 ataccacaat cgattacgtg actacgaaac aagcactgaa accgaaaaga cactccaata
    15481 taacgattta tacgatcgaa tctgcactgg acttattttt acaattagaa gaactaacga
    15541 aaaaagaaca ctacgatgcg attatccaca gtatggcagt cagtgatttt actcctgctt
    15601 ttagtttttc agaagaacag ctggcaaaaa acctacccac ttcttcaacg caagaagaac
    15661 tggacaattg gtttgcggaa aatgaacaga cagataccac tgtttcaaag atctcttcta
    15721 acaccgagca tcttgtgctc gttttgaaga aaacaccaaa aatcatttct tatctacgtg
    15781 aatggcagcc aaaagcaaaa atcattggtt tcaaactatt agtagatgta ccaaaggaat
    15841 ctcttctggc agtcgcaaaa aatagtctga taaataacaa aactgatttt attttcgcaa
    15901 atgatttgac ggaaatccat ggcgagacac accacggcta tctcttatct aaagatggaa
    15961 cagtggaaga agctcaaagt aaatctgaga ttgctgcatt gattactgag aaaattagac
    16021 tggaggaatc aaaatgaaaa agatcttact aggcgttact ggaagtattt ctgcttacaa
    16081 aagcgctgat cttacaagtc aattcgtcaa attaggtgcc caggtagatg tgattatgtc
    16141 taaaagcagc acacatttta tcacgccatt aaccttgcaa tctctgtcga agcgcgcagt
    16201 ccatacagac gtcatgcaag aatcaaatcc gcaggtaatc aatcatatcg aactagcaaa
    16261 acaagctgac ttgtttctca tcgcgcctgc tacagcaaac attatcggca agctagcaaa
    16321 cggcattgca gacgatcttc tttcaacagt cgcaatggcg cttccagtgg gaacaccaaa
    16381 attgattgcc cctgccatga acacgaatat gtatcaaaac ccgatcactc agcgtaatct
    16441 ggaaacattg agatctgtcg gctatcagga aattgaacca agagaatctc ttttagcttg
    16501 tggagatttt ggaaaaggtg ccttagctga tattcagacg atcatcgaac aggtcatgct
    16561 gactcttaat gaaagaaatg cttagaaaaa aggagtactt atgaaaaata caaaaaactt
    16621 tacattaact gcgatgtttt tagctatttt gattttatta gctgttacgc ctttaggttt
    16681 tatccctatc ggtccaatca atgcaacaac catgcatatt cctgtaatca ttgcttcgat
    16741 cgttttagga ccaagactag gtgcttttct tggcggtaca tttggactga tcagcatgat
    16801 ccgtagcaca gttatccaaa cacctttgtc ttttgtcttt tctccgttta tcccagtcat
    16861 cggaacagaa catggaagct ggaaagcctt gctgatcgcg tttattcctc gcatcttgat
    16921 tggggtggtt ccttatttcg tttataaagg tctgcgcaaa ctaatgaaac aaaaagcaga
    16981 ttccgtttct ttattcttag ctggactttc cggttcattg accaatacga ttttagtgat
    17041 gaatatgatc tactttttat tccagcaaga ttatgccaaa gtcatcggaa caaatttaaa
    17101 tgctgtttat tcagctattc tagcggttat ttttacaagt ggtatacctg aaggaatcgt
    17161 cgcaggtctt gcgactgcag cagtatgcaa tgtcttgtta agatacttca agcacccttc
    17221 tcttactaac tgatagtcat cgtagccgat ctctgatttt tttctctttt ggtgttacta
    17281 ttgaatggaa agatttgacg tcgaaaggat gatccaaatg aaaatttttg ttgtaggtgc
    17341 aaacggacaa attggccgac acctgataaa agatttagct ccaagttccc atgaaatttt
    17401 tgcaggggtg agagatgttg cttcccaaac attagtaaaa aaagagaatg tttcgtatgt
    17461 ctcttttgat ttaacttggt ccgtggaaaa aatgaccgaa gcattcaaag gcatcgatgt
    17521 attgattttt gctgccggct ctcaaggaaa gaatcttctg caagtagact tggatggcgc
    17581 aatcaaaaca gtgatcgcag ctgaaaatgc gcatgtctct cgctatctga tggtcagtgc
    17641 tgtttatgca gatgaaccag caaaatggcc tgagtccatg acagattatt atattactaa
    17701 acattatgca gatgaatggc tgaaacgaac taacttagat tttgtcattc ttcaaccagt
    17761 cacattgact aacgatgaag aagttacttc cattcaatta actaagccta atgagaaggc
    17821 atcaaaaacg atcactcgct ctacagttgc tgctgtactt gccgctctag tggaagaaac
    17881 ggatatttct cgtacgactc tagtactttc tgaaggtagc aaagagttga atacagcatt
    17941 ccaagaatgg gcaaaggagg aatagatcca tgcgtgccat ttcaatcaag catcctggtt
    18001 ctgtagatgt attagaacaa attgaagtgc ctgttcctaa accaaaacaa ggcgaattac
    18061 tgatcaaagt ccatacagca gctgtcaatc gaacagatat tatgaaaaga gaatcagtct
    18121 ctttgaaacc tccctaccct attttgggag tcgaagtagc tggagaggta gttgagaata
    18181 aaagtgatat ctccactttt actcctggga caaaagtata cggattagtc aatctaggtg
    18241 gttatgccga atatgctgtg atgcctgccg atcgtgcaat ccttctccct gatacgctag
    18301 actatgtttc tgctgctgga atctcagaag tttttttgac tgcttatcaa acactttact
    18361 ggcttggaaa attacaagaa ggcgaaactg tcttgatcca tgcaggagca agtggtgtgg
    18421 gaacagcagc gatccaatta gctagacagc tttctcacgc gaaaatcatc gttactgcag
    18481 gatcagaaga aaaactcgcc ttttgtaaag aacttggtgc agatgaattg atcaactata
    18541 aaaaacaaga ctttcaagaa gaggtacgaa aaatcactga aggtcgggga gtcgatgtta
    18601 ttttggattt catcggcgct tcttactggg aaaagaattt agcttctata gccgttgatg
    18661 gacgttgggt cttgattggt atgctaggtg ggaccatcgt gcctgagata gaccttggtg
    18721 tattgattgg gaaacgtgtc caactgcttg gtacattatt gacacctaga agtgatcagt
    18781 ataaagcaga gctcgcacaa acttttatgc aaaaagctgg gccttttcta gaaaatggca
    18841 agattcggcc aatcattgac cgtacattcc aattcagcgc agtcaaacaa gcgcatgaat
    18901 atatggaagc aaacaaaaac atcggaaaaa tcattttgaa gataactgaa taaaatcatg
    18961 ctgatcaaaa aagaggctgg gacagaagcg tttaactcca agaaataaga agaaattcac
    19021 gaaaattgct tttcaaattt ttgtgaattt cagcttattt ccgaaggaat ttcttctgct
    19081 tccgccgttt atacgtgttt agagcgtgag acaaaagtgt tctttacttt tgtcccacgc
    19141 tctttttccg aataaacggt gttcaaaagc ttgcatctgc ggtaataagt ccaaccaagt
    19201 taaaaacata agaagctgtt tttacttggc tgttcttatt acttgatgca gggcagcttt
    19261 ttcacaacct cttcactaaa cagtgttcaa tcagctgacc ctcggtatta gctcaaaacg
    19321 ctgatttcac aacctctttt tatttacgtt ctatttcatt cattttccga agcaaatcga
    19381 gctgcttgta tgcccgcttg tcgcccaaaa ataatgatct ccgcaactga atttccaccg
    19441 atccggttgt ttccatgtaa gccacctgtg acttcaccag cagcatataa ccccctaatt
    19501 ggctggtttt ctttatctaa tacttcagtg ttcgtattga ttttcacacc gcccatcgtg
    19561 taatggattc ctggtgcgat tttgatcgca taataattcg gagacgataa gtcatgttcc
    19621 atggctgtgg cacggttgaa ttgagcatct tttttctccg caacatccgt attccatcca
    19681 tcaactgttt ttgctagtgt ttcttttggt aaatcgattt tttctgctaa ttcttccatt
    19741 gtctttccag ttgtgacata tcctttttgg tcataaaatt caatagctgt ggcacgatca
    19801 cgcacgcctt ggtcaaaaat caaataagct gatttttcag gcaatgctgt aattgctgca
    19861 gatactttat cccttgtatc catttcattg acaaatcttt tcccctcttg atcgaccaag
    19921 attgctcctt ctccgcgaac aacctcacca atcaagaccc cctcatcctg ctgcacagtt
    19981 ggatgaattt gtattttatc catatcaacg gtttgtccac ctaatttttc aatcatggtg
    20041 ataccatctc cagttgatcc ttcttgattt gtcgtaatat aatcagctaa atcgggacga
    20101 tatttttcaa taaattcttt gctggcacca aaaccgcctg tggtaactac gattgctttt
    20161 ccggtgacct cttttggttc ttctccttga acatgtacag tcacttcatt gaccgtttcc
    20221 ccatttttct taatgtctgt cacatctgcg ttgacaaaaa tagggatttc ccgctcatgg
    20281 acgttattca ataacccctc cactaagtat ccaccaatag ccgagccatc agacggacga
    20341 tgtgtcctct tttcactcat ccctccagtg atcgttaagt tgtccagttt gataccgttt
    20401 tgatctagcc aatcgaccgc atcagcagag tgatcgacaa agtatcgaag catttcttta
    20461 tcattcgttc ctccaccacc ttttagcgtt tcttcataga aggcatcatt cgagtctttg
    20521 attccttctt ctttttgaaa ttttgtttct gaagcattca taccgcttga tgatttagat
    20581 gtgtttcctc cggcaacagg catcttttcc aaaattactg gattcaaccc agcatctttt
    20641 gcttcgatag ctgctgccat ccctgcacca ccagctccaa taatcacgac atcataagat
    20701 tctttcattt cttttggatc tgtatatact tgttcagaag cgcctgatga tacttcggca
    20761 gattccttcg tactagaact tgtctgcgct gtatttttct gatctgcgcc gcatgcgctc
    20821 atagcaagaa gtgcaacggc tgttaataaa ccagcaacta attttttcat ttgtatcccc
    20881 cttttctcct tatactatat taagtgattt ttttcacaat atcaactctg tttttcttta
    20941 agtcatatag ctttggtaaa cacacgcttc ttagtataat taaggatata catgaaggag
    21001 ttattttatg aatcatttga aaaccttttt tacgaacagt acaaaaactg caggtagaat
    21061 cacaaacgga atctatattt tattacgtat catcgtcgtt attatgctag tggatcaggt
    21121 ctggaaccaa cactggggaa atacaatgct tttattactg acattaattt tatttgaaat
    21181 cccttatttt ctggaaaaga tattaaagat acagattcca aatatgctag aaatcatttt
    21241 gttatctttt atttttagtt caacagtttt aggagagtta agtgattttt atggctattt
    21301 ttcaatgtgg gatacttttc tacatgcatt cagcggattt ttagctgggg gtgtcggctt
    21361 ttcccttgtt tatttgctca ataaaaatac aaaaaccatg aacttgactc ctttattact
    21421 agcagttgtt tccttctgtt tttcgatgac agttggtgtt atgtgggagt ttgtggaatt
    21481 ttcagcagat aaattactgc aattcgatat gcaaaaagat acgatcatcc agcaaatcaa
    21541 tagtgtggag ttaagtaaag acggaaacac tgtctatcat gttccagata tcactcggac
    21601 aatcattgaa agtcaaaatg cagatggtaa aacagataaa acaatcatcc aaaatggtta
    21661 cttagacgtg ggaatcatgg atactatgaa ggatttattt gttaatttta ttggagcagt
    21721 tgttttcagt gtatttggtt acctctatag tcgaaacgat taccaaaaat ttacgttcat
    21781 caagaatttt attcctaaaa aaatcaaacg ataaaacatg ctaaaaaaca agagaagggg
    21841 cagtgacaat acttttgtca ctgccccttc ttttttgaat gtatggcatg ccattagtta
    21901 tccgatagta ttaactcaaa aaagtaagat atgaggaatg actatttcgt tttttatccc
    21961 aatactgagg acttatttca ccatttcgtt atttatctaa tttacttaaa acctgcataa
    22021 ctttttcata atctggatta ggtgtgccgt ctagattttc agcaataaaa gtaaaaccca
    22081 tttttttata aagagcaatc gcctgatggc tccatgtctg tgtgtgaaga tagattggtc
    22141 cgtccgtatg gagggtagga aattcttgca agactctggc agtcaatgct tttgcgagcc
    22201 cttttccttg gtaatctggt ttcactgcta accaatgaaa aaccggatac acttgctctc
    22261 ttgatttttt tcgccaagcg gtacaggttg ctactttttc tccttttttt gtctctacaa
    22321 aaaacatcct tctttcaagt tcttcaggat aaggagcaaa gttttgttga aaatactcaa
    22381 gtgcttcatc tgtcgtttga aattccccaa cggaagtctc aatctccgcc caagcagatt
    22441 catcttcttt ttgataaaat cgaaattcaa aaccttccgc taaaggcgtg attggaacat
    22501 tttgttgaag tggtcttgtc atccagattt ctgcgtaagg taacgtttta tctaacattt
    22561 ttctatccct cctcgtctcc attatgccaa ataacatatg actcagctac ttatttgact
    22621 ataacagata gagatataaa tcagaaccag tcatctgcgt caaattcatt tcgattagcg
    22681 tatacccatg ttcctgccat acctcgcatg aaatctccta aagcagaaga aggaatacct
    22741 ccaccaggtg cgggtgttcc cggactagga agtggtactt gcggctgcag atgctcatcg
    22801 gtggaatcaa tagttgacaa gcgttttttc ttcgtttcct tctggtcatc tgattccttc
    22861 tgatcttccg actgtttagc aacaaattct ttttctgatt gttgttttat tttaggctct
    22921 aaaatttcat tttccaatcc agaaacttgt ggggccaaat gagcttcttg ccttatcgtt
    22981 ttattagatt ctgagatttt tctagatatt cttgctaact ctaggcttct tgtttgtttt
    23041 actttccctg ttggagaaac tgcatgagcc atttgttgtt ttttttctga caagctttct
    23101 tcttgtcttt tttgttcttt ttgatctatc tgtttgttta atggtaaaac atgtaatagt
    23161 gactgagcat ggagttcttg gagtgaatac gggtcatgat aactatacat aatcgtaaaa
    23221 tcacctgttt gtttggtcaa ataaccatcc tccaatggta cttcattgat tgtaaccgat
    23281 acatccttta acggtacggg tttacctaag gaatttgttg ctgattggat caactcttct
    23341 ttgtttattt tttcgtttgg atgaacaata agatcatgac cttctaatga acgattgtct
    23401 ggtatataaa cataagtaaa ggtaatttcc cctcctgatt gcttcctatt attcatcagt
    23461 tctgagtgaa gtacttcaag gatctccgac cagtgacttt ttctgtctaa tccgtttgct
    23521 tgcatccaat cagaaataga agtgactttc ccattttgtt cataagtcga taaatctata
    23581 tttggcactc gatcagaaaa ttcagcaggt aggcgcaaat caggaatacg atttacacta
    23641 ctcatatgtg tttctgcttg aagttcttta tttgtttgac tatctataaa atgagtgatg
    23701 acagtcgatg aagcagcaga tgcttctaca taaactacag ctgttgtttc tgccacattt
    23761 gatgttttcg agtctatata agttaataca acgggatatt ctcccggagt tgtagtatct
    23821 actgtcccgt tcattttgat ttcttcttta tttcctgaag ttccatcgct ttttgttaca
    23881 tattcaacaa gatctttagg ggcgtaactc tctcctgttc ttaagtgaag atcttttcct
    23941 ttgatagctg tttgatcagc acgaacatgg atcacagcag atgcagtcat tgtttttaaa
    24001 gcaattggat caaaatagga caaggaaata gtagatgttc ctgtattagt cgtatccacg
    24061 atattcccat tgtttgaaat tactttggac atatctcctt gtgttccatc tgcgttcttc
    24121 agcctttcta ccagatcaga tatcgaaact tttgtccctg ccagaacatc gattttcttt
    24181 ctttcaaact gtgaataatc tttttcatat acataagaaa cttgtgcgct tccaccgtcc
    24241 tttatatctg tcaaagcatg attcaaaata tcagtgatct gttttaactg atcacctttt
    24301 gtaggatcag tcatatcgga aaagatagaa agcggcacac tgcttccggt ttccgatgtc
    24361 cataatgttt tgttaggaat taaccagtag tggtttatcg ttggaggata actgacttta
    24421 ttataggaag tcaatgcagg aagtagctgt tttccatttg catcagtgaa agtatgagta
    24481 atagtgatag gggaatcagt ggtctcagaa acagaggtac gtacgacctt gatggtttgt
    24541 gtcgttgcct gaacgggtac atgcatatag acacctacag ataaactgat cagcatcgtg
    24601 cgcatcataa acttaacgta gtgtttttca gaacacgacc gttccttatc taaacgacaa
    24661 gcgtgtttat ttagttgttt tgaacgtctt tttgaacaca tttattctta gtcctcccta
    24721 ctcttgtcta aacatgaagt agtaattttc ataagatgat ttcattatat aaataaaatc
    24781 aaaagaagat ggactattag gagagtattt tttttgattt tttattgttt caagaaaatc
    24841 ggaataataa cttatgtact ttttaatttt gttaagtaat atatctagtt atatctagtt
    24901 atatctagtt accttttctt tgaaaaaaac ataaatcagc taataaatat gtgagacaaa
    24961 gctgccatcc ataaatacta gctgattttt tcagttaaat gtctattttt ttctctgatg
    25021 atggtatttc caaaatattc ccagtcatct ggagtcggtg gatttttcca aattatctgt
    25081 tctttattaa atttttcaag taaacaatca gataaataaa tattcgtacg agaagtgatt
    25141 cgactctcaa tcacaatatt gtaattttta aatcctttca cttgagaaat aatgtaatcg
    25201 gtataagcag atccttgcga aaaatcaata cagacatgaa tcggtgcttc aaaatatgat
    25261 accggacaaa taccgaccaa taaaaagaga taatcataaa ataagcgaat catgaaacgt
    25321 tcatcttttc ccaagaaata gcgtttattc tcttgtatga ccttttggat tgctgtactg
    25381 aatattggat acgtctcgaa gaaaaactgt agctgctttt tagacgtaaa gctagtcatc
    25441 tcaaagtcga atatccaatt ttttcgattg acatgcatca tacccatacg aagttctttt
    25501 cgtatatata gtctttcttc ttcagagatt tcaatcgaaa atggtaattg atcaatcaat
    25561 tccactgaca ttttttgact aatcatgtgg atatcatgaa aatgagcttc cgcaagtcca
    25621 aatgcgccat ctaattcaaa ttcttcttcc gtgatcaaaa acaacatgat ataagaaatc
    25681 tcatcaatga tctgctcttt agggatatga agaaaagaaa tatgtgataa atccttgatg
    25741 atcttcattc cttctgagct cttaaagtat tcatctgaaa agaaacgttt tccgattggt
    25801 tgattcccat aggccctcaa caaactaata gtggttagca aattgaattt gattcgtttt
    25861 gttgcagaca gttttaaatt gaacagatat tcaaaatatt gcacgatact ctttgcttca
    25921 ttcatgacgc tttctctaaa tggcatagaa aaaccattaa agaccccgaa atatacccca
    25981 aataatacgt tccgtatgtt tatttcttcc ccaactaata tgtttttctt taactttatt
    26041 tgatgctgtt caagaaaaga gactaattct cttcttttta cataggctct tgatatgctt
    26101 aaaaaatgat tctctgcaaa tttttcgatc gttacttttg aatccacgat ctccgttaac
    26161 agtcgagcaa tttttgatcg ttgaaagtag attcttctta aatttttgat atccgtcaaa
    26221 ttcagacgtt cgacatggat ctctgcttct tctgaaattt ggatctctgg ctttgttttg
    26281 aattcagtaa attctttatt taattctatg atataatttc ttgttttaaa tttagacaaa
    26341 cctaatgttt catataactt aggcagcact acataattct ttttctcaaa ttctaaatat
    26401 ctagctagca gcagtttttc tctatcttcc tcttctataa ggtaatccaa cttcatatcc
    26461 tacacctcaa aaaatgcctc ataccaatta cttgatatgc agatgaaagt tcatcttttc
    26521 acctatactg attttatgat ggattatgct tgttttttca tcagttattc tcatttttta
    26581 tctttttttt gagaatattg caaaaaatgg aaaaatttat gaggaaatat tctatatttt
    26641 ttgttttatt gtgttaaaat gtacaagatt tgcgccattt gcgtaaacaa ccacaaaaaa
    26701 gagcaggacg gccaccgtcc tgctctttta cttattttaa gttccattac ttattaattg
    26761 gctaaacttc tgcttgtttc tgatattgct tgtttttctc caatgatccg cacttctgtt
    26821 tctaaagaca catcaaattt ttctttgatt acttcttgga tgtgcgcaat caattcaata
    26881 taatctgtcg ctgtcgcatg atcgatattg acgatgaatc cagcatgttt ttcagagact
    26941 tgtgcaccgc cccatttcag gccttgcaat cctgcttgtt ggatcagctg acctgtatag
    27001 tgtcctactg ggcgcttaaa gacacttccg catgaagggt attctaatgg ctgttttgat
    27061 tgacgcaatt cggtcaactc atccattctt gctttgattg cttcataatc ccctgtttgc
    27121 aaactgaatc gagcttccaa tacgatagca cgtaattctt ggactttact gtgacgataa
    27181 gaaaatacca tttcgtcttt tgtcaaagtt ttcaatgttc catcttcaag caaaagatcc
    27241 acttcagcaa aaacatcttt gatctctccg ccatacgcac ctgcattcat ataaaccgct
    27301 ccaccgacac ttcccgggat gccgcaagca aattcaaatc cagtcaatga ttctgccaaa
    27361 gctgcataag tcgtatcaat cagtgaggca cctgcttccg caatgaccat cgttcctttg
    27421 acatgaatct gtttcatttc agtcagcatg atgactacac cgcgaatccc gccatcttga
    27481 acgatcagat tgcttgcatt tcctaatacc atccaaggta tatcatggat tcggcaataa
    27541 tcgatgattt gctttacttc ttcttgtttt ttcgggaatg caaggacatc agctggtcca
    27601 cctgttttcg taaacgtata gttcatcaat ggttcatcaa acaatatagt aatcgtggct
    27661 aagctttcaa ctatttcttc tttattcact gaggattttc ctttcttttc tcaaacgtcc
    27721 tcattattct atcacgctta atacaatctt gccagtcttg ttcaaagttg atgacggtag
    27781 tgatctttaa gcacttcctc acataattca tgacttctta caacttcttt ttgtttaagc
    27841 aattctgttt ccgatttacc taaacggatc tgagaaaaga aggcctctac cattggctca
    27901 aacccgcgtt tgactagcgt gtttgtccag tcgccaaatt ctttcacttt ttttccatca
    27961 gcatcttgaa tgacaagctg ggtcagatcg tttacttcat aagtaccatt tttacttgtt
    28021 acttgatatt tttctatatt agcgccactt gctaaatcca tcgttaaaat agccgtttga
    28081 ttttgtgttt ctaattgtaa aatggcatat tccaaaaatt cctttgtttc tcttatctgg
    28141 tattttgttc tcaaaatggg ttcatctaat aaatacacag ctgtatcaat aagatgtaaa
    28201 aacaaatcat aaaggacgaa ctctgtcgtt tcttttgccg ctattcgatt tttttgcagg
    28261 tggatcaacc gcttatctgg gatacgtttc aattcttcta ccataggagc aaagcgccgg
    28321 ttgaaaccga tcatcaaaat tatttggttc ttatcagcta attcttgcaa ttcacgaact
    28381 tcatttagat ggacactcag tggtttgtca atataaacat ggataccatt ttctagacat
    28441 tttttggcta attcataatg tacttttgtt gctgcgtgga tcatacatgc ttcgattttt
    28501 tcttctaaaa gctcatcgat cgtttcatat agatgttgga acccgtactc tttttgaatt
    28561 ctttcttttg tttctttatt tcttgttgca aaataaaaat caagtgttcc ttgttttttc
    28621 gcataagttg gtaaatatgc tttttctgcg atattcccta caccgattac accaatcttc
    28681 atctactttc ctcctggatc atttagttac tttcatctta caccattttt tactaaaatg
    28741 aggtacaata gtatcgcaaa ggtaaggaaa ttaattcgaa ggagtgtgct tttattgaaa
    28801 tttatctctt ggaacgtaaa cgggcttcgt gccatcgtaa ataaaaattt tttagaagtt
    28861 tttcatgagt tagacgccga ttttttctgt ctgcaggaaa cgaaactcca agcaggacaa
    28921 attgatttag atcttccagg ttattatcaa tattggaatt acgcggaacg aaaaggctat
    28981 tccggcacag cgatttttgc taaaaaacca gcattgaatg ccacttacgg aatgggtatc
    29041 gatatccatg atacagaagg ccgtctgatt actttggaat attccgattt ctttcttgta
    29101 acctgttaca cgccaaattc tcaaagcgaa ttaaaacgtt tagattaccg attagaatgg
    29161 gaagaagcct tttataatta tttggaaaat ctaaaaaaac aaaaaccagt catcgtgtgt
    29221 ggggatctaa atgtcgctca tcaaaagatt gatttgaaaa actggaaaac gaatcaaaaa
    29281 aatgctggat tcactccaga agaaagagcg gctctttctc gactgttgga taacgggttt
    29341 atcgatacat tccgttattt ttatccaacc caggaaggtg tctactcttg gtggaactac
    29401 cgattcaatt caaggaaaaa caatgctggt tggcggatcg attacttttt gacgagcaaa
    29461 gatttagagc caggactagc tgatgcaaag atccatacgg acattatggg cagtgatcat
    29521 tgtccagtag aattagattt gaaataaaga ggttgtgaaa aagtcgttta gtttcgagta
    29581 ttaagaaaaa ttttgtgaaa atggctttcc acattttgca taaatttggc ataataccga
    29641 gaaactggct tttgaacact gtttatcgag agattgtgaa aaagctgtcc tgcatcaagt
    29701 aataagaaca gccaaacaaa aatagttcct catatttttc gtttggttgg gcttattacc
    29761 gcagatacaa gcttttgaac accgtttatt aagaggttgt gaaaaagctg cactgcatca
    29821 agtaataaga acagccaaac aaaaatagtt cctcatattt ttcgtttggt tgggcttatt
    29881 accgcagatg caagcttttg aacaccgttt attaagaggt tgtgaaaaag ctgcactgca
    29941 tcaagtaata agaacagcca aacaaaaata gttcctcata tttttcgttt ggttggactt
    30001 attaccgcag atgcaagctt ttgaacaccg tttattgaga agttgtgaaa tcagcgtcct
    30061 gacctgagta ttagagaaac aaatggcaaa atagttcctc atattttgct attttttgag
    30121 ctaataccga gggtcagctg attgaacacc gtttagtgga gaagttgtga aaaagtcgcc
    30181 tactttcgag tcgtaagaaa tttttttgaa aatggttcct cacaactttg cataaatttg
    30241 acttaatacc gagaagtcat gatccccatc taactccaaa tcacaaggaa tgagttcaaa
    30301 aactagcttt tctcaacaaa tattacataa aaaattctat gttttttgtt aaatttattt
    30361 gcttttttca aaagtatgtt acagtaattt cccaaggagg ttttacagaa atgaattttg
    30421 ttgccatgga ttttgaaact gccaatcatc agccttatag tgcttgttct cttgcgctag
    30481 tcatggtaaa aaatagccag atcgttgatg aattctatac attgatacag cctgagactc
    30541 cttttttctg gcgaaatgtc caaattcacg gaatccatca agaagacgta cgcaatgcgc
    30601 cgaaattccc agaagtctgg caaactatcc aaccatattt tcaaaaaaat cgtttagtcg
    30661 ttgcacataa tgctgctttt gatacaaagg tcttagcggg atgcttagat tattatcatc
    30721 ttgaacagcc taattatctt tctttatgta cagtgaaaag tagccgtcgc ctgtttcctg
    30781 aatttccaaa tcatcgattg aacactgtgt gcgaaaattt gaacatccaa ttagatcatc
    30841 accatgatgc attggaagat agtcgtgcat gtgcggaaat cctgctttat caagaaaaaa
    30901 aattcgggac agatccattg aaaaaacttg tgactataaa gtaaaagaat acttatgaaa
    30961 cacacaaaga ggtcgtgagc ctgccgtttc actccgagtc acaaggagca atttcaaaaa
    31021 atagcttctc atgtttatta aatattgtga ctggtgaccg aggagctggc aggagaacac
    31081 cgtttattgg agaggttgtg aaaaagctgt tctgcatcaa gtaataagaa cagccaaaca
    31141 aaaatagctt ctcatatttt tcatttggtt ggacttatta ccgcagatgc aagcttttgg
    31201 acaccgttta ccaagaggtt gtgaaatcag cgttttgacc tgagtattag agaaacaaac
    31261 ggcaaaatag ttcctcatat tttgccgttt tttgagctaa taccgaaggt cagctgattg
    31321 aacaccgttt attcaaaaaa aatggactgc gacacgactt ttgtcacagt cccttcgtgt
    31381 gtttttctgc cttctcaaaa ggatgacagt ttctcactct tttcctattt cttctattca
    31441 atcaaataac tcattttata tacatctaaa aattcaccta gatctgttct tgcccctcta
    31501 ggcatgaccg cttcgatttg gaagcccatt tttcggtaaa ggtgtacggc tctttcatta
    31561 cgaacttgaa cgtcaagctc caatcgaaaa agtacaccca tttccttcgc ccaactgatg
    31621 atttcttcta gcataagagt gcctagtccc attccccaat attcctgcag aatactgata
    31681 ccgacttctc ccacgtgaga caaacgaaat tgactgtctg ccttgacaga tgctgttcca
    31741 ataatcgtcc cttcatagat tgcaagcagc aataaattat tattgctttc gtatatataa
    31801 tccaactctt cttctaaggt ttctggtggt aacaggagtt ctgcttcatc caaaactaaa
    31861 aattctgtct ccttattaac ttgtcccatc atcaaaagaa tgtcttttgc atctcctggc
    31921 actgcttccc gcaagatgat cccaacttct tcactcatga ttttcagccc atttttctag
    31981 aattcgctgt ttgaaggttt cactttgctc cccgtatgag attagtttca cataccgctt
    32041 ttctaaatct gtatcacttt tttctaaaat cagttccaaa taatcctccg gcagtgcttc
    32101 ttctaataga tttccccatt caacaacgga aagcccatca ccttcaaaat attcatctaa
    32161 ccctaaatct gctccgctag ctgctacccg ataaatatcc atatgataca acggaatccg
    32221 accttgacta tattctctaa taatcgtgta tgtcggactt ttgatcattt gcgttatccc
    32281 taatccttgg gcaattcctt tcgtcaacgt tgttttaccc gcacctagat caccagtcaa
    32341 tatcagattg tcacctggca ttgcggaatg accaattgcc tctgcgaatt gttctgtcat
    32401 tgttaatcct gatagttcga tcatttttca tcttctcccg ctcttctttc tttttgccag
    32461 tatatcgcgt aatgaagttt ttttaaagaa aaaatgaact agtcaagaac agcagctgct
    32521 gtttttggct agttcgcgtg tatttgttaa tcaatcaatg tttgtgctgc tgtgataatc
    32581 gataatttat atacatcttc ttcatttgct ccacgagaca aatcagaaac cggtttgttc
    32641 aagccttgta gaattggtcc gattgcttca aagttaccga aacgctgagc aattttatag
    32701 ccgatatttc ctgactgcaa ttctggaaat acaaagactg ttgcttgacc agctacttct
    32761 gaatctggcg ctttcagttg tgcaactgaa ggaacataag aagcatcaaa ttgcaattcg
    32821 ccgtcgatca tgtattgtgg cgctagtttt ttagcgattt tagttgcttc aactactttg
    32881 tctacttctg gcgatttcgc tgagcctttt gtcgagaagc tcatcattgc tacttttggt
    32941 tcgatatcga acaattctgc tgtttttgca gaatctacgg cgatttcagc caattcttgc
    33001 gcagttggat tcacgttgat cgcacaatcc gaaaagacat atttttcttg atctcttcca
    33061 cgtaccatga tcatcgctcc gcttgtccga ctgatgccag gctttgtttt gatgatctga
    33121 agtgctgggc gaacagtgtc gccagtcgaa tggatcgctc cagagaccat tccgtctgca
    33181 atccccatat acgtaagcat cgtaccaaag taattcacat cttttaaaat cttttctgct
    33241 tgttctttgg atgcctttcc atttctacgt tcaacaaaag tatccaccat ttcatcccac
    33301 ttatcgtaat tatcagggct gatgatcgta aagctagatg ttttgattcc tctggcatgc
    33361 gctgcatttc ttatttcttc ttcgttccct actaaaatgg gttccacaag ttcttctgct
    33421 ttcaaccggg cagctgcgcc taaaatacga gcatcagtag cttccgggaa aacgattttg
    33481 atcccacggc gaacaatttt aaatcttaaa ctatcaaaca attccacaag atgacctcca
    33541 gacgttttta tatgtattat catacactat tccagaaaaa aagaacagtt tattttatct
    33601 gtatcagtca aaaatgctgg aaaaattaag tttttcacat acaaagcgaa ctgcactata
    33661 acaggaaagc gctgttttat tacactgttt caggcagttg ccaatcaatc ggttcttctc
    33721 ctaacgcaag gagcgcatca ttcgttttcg agaagggttt ggaaccaaaa aagccacgac
    33781 ttgcagataa cggactggga tgtggagatg ttatgatgat atggcgactc ttatcgatca
    33841 ttttgatttt ttcttgtgcc ggttttcccc acaagataaa cacgattggt ttttcccgtt
    33901 catttaattt ttcaatgatc gtgtctgtta atctttccca acctttcccg cgatgagaat
    33961 acgcttgccc ttcccgaacg gtaagaacgg tgttgagtaa aaggactccc tgtttagccc
    34021 atgacactag atttccatgt tgaacaggtg cgattccaag atcatcataa agctctttat
    34081 agatatttct taacgatggc gggatcttta cgccaggttg cacagaaaaa gataagccat
    34141 gagcttgatt ttctccatga taaggatctt gtcctaaaat caccacttta acttcttcat
    34201 aaggagtcaa ttccaatgct tcatagatat gatacatatc tggatggatc ttttgggacg
    34261 catattcttt ttttaaaaat tctcttagat gcagataata atcttttgaa aattctgagg
    34321 acaaaacttc ttgccaactg ttatgaatga tttctttcaa aaactccacc tcctaataaa
    34381 aagaataact cacattttct tcaatcacaa gggacaatct tcaccctcag cacttgatta
    34441 atatggtaaa ctaggaacaa gaagcagaaa ggaacgataa tcattatgat caaattaatt
    34501 gcatcagata tggacggcac attattagat gcccatatga gtgtttctcc tgaaaatgcc
    34561 gaggcgatac gttttgcaaa tgatgccggt gttgagttca tggtcgctac tggtcgaaac
    34621 tatcaagaag ctcgcgcagc tttagatgag gtaggaatcg attgtgcgat gatcactttg
    34681 aacggggcac aggtatttga taaagaagga aattcattgt ttaccgtgtc gattccaaat
    34741 aatcaagcaa tctctgtttt agatattcta gatgctaacg gtatttacta tgaagtagca
    34801 accaacgatg gtctttattc tgaaaatcaa gcgaaacgaa ttgaaagttt tgcttccatg
    34861 gtggctaccc atttacctca ccttacgtat aaaatggcga ttgccatggc ctcagctaag
    34921 ctggagttat tgcacatcac atacgtggac agtattcgtg ctattttgga agaaaagaat
    34981 ctggaagttt taaaaattat ttgttttcat acagaagggc cagctgtatt aggtccagtt
    35041 ggaaagcaga tttctctttt aggcgatcta gccgttactt cctctggtca aaacaatatc
    35101 gaagtgaacc ataaaaacgc tcaaaaagga attgctgttg cccatgtcgc tcacgagcgt
    35161 gggatttctt tagaagaagt catgacgatt ggcgataact tcaatgatgt cagcatgctg
    35221 caagtagcag gagtcagttt cgcaatggga aatgcagaaa tcgaagtaaa agattatgcc
    35281 aaatatacaa cggacacaaa ccttgaatct ggcgtaggaa aagccatatt gcgcgcgatt
    35341 gcagaagact tgtagtttta tctagaaaag agggatatag atgtcagaat ttttcattca
    35401 ggaaaagcag cttggacgtg caactcggac aattgtcaaa aacgaaaaag gacattccct
    35461 gtttttgatg gttggtcgct ggggaacaaa gggcgatgca ttgtctcttt atgccatgaa
    35521 tggcgatctc gttgctcaca tcaagcagat aagcctgaca ttcggtacgc gttttgagct
    35581 gtataaagag ttcgaaaagg tgggaaccat gcagaaaata ttcaattggc ccggtgactt
    35641 ttattatatt cgtagacttc actggacagt ccaaggtgat atctataatc atcaatatca
    35701 aatccatcat ttcaatcagc aaatcatgaa aatggataaa gcaacacttt tttcaggaga
    35761 ttactatgta ttggatgtct caaatgatga agatgctcca gtttgtattt gtattgctgc
    35821 ggttttagat tactggctct accgtaaaga caaaagtcgc gataagcctg tttcttaccg
    35881 acttaactta agttaaaaag atgtacctga aatgcggaaa tacgcatttc aggtacatct
    35941 ttttagatat tcttttgcat atgatcataa agatgaccac tgatcatccg ctgaccgaca
    36001 actttgaagt catggcgttc gtataatttt ttagcctttg gatttttttc atccacactt
    36061 agaccgatga cggagcgatt agctttcttc gccaatttag gtaatgcttc taataatcgc
    36121 gaaccgatgc cttgtcctct aaaatcttct gatacactga tagagtccaa ataccattcg
    36181 ttgggaaacg tttctttatc aatgaacaaa cgtgtagacg catctagctg atatttctct
    36241 aagataggta ccagtggctg atcgatgatt gattcttctt catctgtata accgtaagca
    36301 actcctgcaa ctttaccgtc tatttcttct acgatacctc gtgaataact gtaacgataa
    36361 tttggatcag tgattgcttc ttctaaaatc tctaaagtct tttgttcccc tgtctgcttc
    36421 aaaaatggca gttccatatc ttttagaatc actaagatca atggggcgat ttctggagca
    36481 tcttcttttc tcgcaaaacg aatcatagtt tcctctcctt ttctccattc taacatgcag
    36541 aaaaagaaat cgcaaaatcg ttattttaaa aaatcttcaa tcttttcagt aatgaaataa
    36601 ccatgagtaa cgattcttgc cgcttcagtt cggcaataag ggcagacgac tggcatttct
    36661 ttatcattat gttcgactac attattgact tcttcgtatg caaatttttt tccgcaatta
    36721 gggcatttca ttttttccat gttatctcaa cttcctttca tctttactct cttagcttac
    36781 tcttatattg taaaaaagag aagcaatatc cttcttctat gcagatatcc atacctgacg
    36841 gtcctgttct ccatctatta atcggacttt ataataagga cgttcatctt tgactagaag
    36901 tgtccactct ttcacttttg cttttttccc gtagtagctg actgcttcct tcatcgctgc
    36961 ttgcggttgt ttgaactctt ccgttttttc tatatcaaaa agatgttctg cggccttttc
    37021 cgtgtcattt cgtacggttg ttttcccagt ggatggattg actgctatga cttgtccttc
    37081 acaaaaaaac tggtattcat atgttgcatt cgtaggattc tccaaatctt tttcaactgc
    37141 aaaatgaata gcagatatgt tatgttcttt tgtttcgttt tttacgattg ctgctgcttt
    37201 tttcaatgag atccgatatt cctggtcact aatatcatcc atgtgaaaag cggcattgag
    37261 cagtcccgtc ataccggtaa tccctattac gatgagggca gcaacaccaa acatcatttt
    37321 tttcattctt cattctcctg tttctttttt ttaaagaata tcaagaaatg aacgaatgaa
    37381 aaatcgaatg aaacgaaaaa aaagtgacaa ttttgttatc tttattcgtg cagttctaat
    37441 ggcaatccgt ctggatcaaa gaaaaacgtc attttttttc ctgtaaaggt atcttctcta
    37501 atcggttctg attcgatccc taaggactgc aattctgcaa ttgtttcttc aatatcgtct
    37561 actttgaaag caagatgacg caagccacaa gcttctggat agtttggtcg ttgtggcgca
    37621 ttagcaattc caaaaatctc caattcagca cttcctagtt tcagatctaa tttatagtca
    37681 tctcgttctt tgcggtaatt ttctctgatt acttcaaatc ctaatttatt aacataaaaa
    37741 tcacgtgatt tctgataatc tgaaacaatg atggctatat gatggatcgt tgtaaggttc
    37801 atatgagcac tcctattctt cgtttaagct cggatctata ttaatctcca gttccattgt
    37861 aaatgtgtca gattgaaaaa aatagctgtt tttccttttt ataagaaaaa aggcaaaaaa
    37921 aacagaaagt aggtcctcca agacactctt cctgttccca atataataaa tgaaagtaag
    37981 aaattatatt ttcaagaaaa caaacagaaa attatcataa cacaaattat ttataattga
    38041 aagactagtt ttttttcaag aaaagcatac aatagattgt gttagtaaat acagaacaca
    38101 ctacatttag tgtcttaagg agtcctcata catgaagtca tattttcagt ttttagctca
    38161 tcagctaaaa ggctggccgc aacaaaatta ttatcttttc tttttcagtc ttggctgcca
    38221 ggtcatgact cttgtcaata gtcccatcac ttggctgtcc gttattacat ttatcggtac
    38281 cacgcttggt gtattgtgta ttttatccat caatgcggca aaatcagtca acggtatttt
    38341 aggtattttg tctgcgattt gttttattat cgttgggttt tcagcaaaga actatttaag
    38401 tatcggtgaa cagattgctt atatgatcac attggatatc cccgtattgt taagtaaaga
    38461 atggaatcat aatatggctt caaaaatccg aaaattcact ggaaaaagct ggtttatcgc
    38521 aatcatcagt actttccttg tctatcttgt ttcaggattc ctgattggtc gttatacaga
    38581 tgatcctcgg ccgtgggtag atgccattgc tttttctatt agcttgactg ctggtatcat
    38641 cagtttcttg cgttacaaca accaatatta ctggtggtta gcttcagggc ttgctcaaat
    38701 ggtcctttgg tatatttcat ttacgcatgg atctgcaagt ttggcgatgt tcgtgaacag
    38761 ctctgtttac ttgctgaatg atgtccttgc atttaccgtt tcaccttggt ataaccaaaa
    38821 agaacgtgaa cgtatgcaaa aaatggaaga agaatactac aacgcacaac aacacgcata
    38881 aaaaaactga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    38941 aaacggcgga atcagaagca actccttcgg aaataagctg aaattcacaa aaatttgaaa
    39001 agcaattttc gtgaatttct tcttatttct tggagttaaa cgcttctgtc ccagcctcta
    39061 ttttttatag taattccttc agatactttc ttgcctcatc attgaaacgc agtgattctt
    39121 ctaacttctg ataatattcc aacgcttgtt tctgagcttc agtaaaacga taatgttttc
    39181 ctttccattt gtcgattgtc tcttgcacat ttccagattg gatatctttc actactagtt
    39241 gccatttttc ttttgagact gtacggtctt tcttatcagc agattgtata gcttctcgtt
    39301 ctttacgcaa tacttttaaa aaaccatttc tgactatccg aggaatgctg tcgaagaacc
    39361 cttctgtaaa accatagcga caatattgct tccaaataaa tagatagatt tttggttgga
    39421 tgaatcgttg gtttttcgca aaatattcca tctgagcagt gacttctggt gttcgttgac
    39481 gttttgtctt tctcaacacg gaaataaatg tttcaaaata agcattagga tgtactggca
    39541 cttcttcata tacgatggat tgccaatctt tacgtaaaaa tgcgcgatag ttgatcaaga
    39601 attcttctac atcctttact aattcttctg caaagtcgtc aaatagttct ttttttatct
    39661 gtcgcttttt tgactgccca ttgatgtgtt cacttatttt cttgatttca ttttccaatg
    39721 cttgataatc cgctatgtaa atcggcattt ctacttggcg aaattctgcg agccgctgag
    39781 ctaattttat atccggtaaa tatggctgtt tcatccgacg attttggtac aagacaaaac
    39841 agtatttttg ccatagtcct tcaggaaaat cgatattctt ctgcttaagc cataataatt
    39901 cgtctaaggc cagatcaact tttgtcattc cctgatggat cgaagctgcc actgtcggag
    39961 agacatgcag gtgatcggca aagtggttga tgcctagttt taggatcttt ccggtttttg
    40021 gcgatttaac gatgtattgc acttttaatt ctctaccaca ctcacaatac aatttttgct
    40081 ggcttcgttt tgttcgaaaa aacggattga tcttgaagtc agaaaacacc caatctgttg
    40141 cagctaaata atgttcttcc ataaaacgag agctgattag atatcggcgg tgcttatcga
    40201 ctagttcccg ctgttttttc gttaattttg catagatctc ccaacgttga ctgcttgtgt
    40261 attgtttaga aattttgatg ggatagcttt tgctgatttc ttttggaaac cattcttcaa
    40321 agacggattg ccattcttcc acggctgttt ctttcctttc taattacaaa aagctggcta
    40381 ctaacataac gttagcaacc agccagtgtt tcttgctaaa ttagtgagtt gttccggcat
    40441 ttccggaaat atcttcttta ttttctactg ctgcttcaac tgcataagtc aaagaagaag
    40501 caatgtcttc taaagacata gaaggcgtac ccactggacg atcgatcact tgatcgggtg
    40561 agaatggcac gtggatgaac ccacctcgaa ttgccgggaa ttgtgtttcg atcaaatgaa
    40621 gcaaacgata catgatatca ttgcagacaa atgttcctgc tgtataagag atgtacgctg
    40681 gtagaccatg atcttgtaca ttttttgtca ttgctttgat tggcaatgag gtaaagtaag
    40741 cggctggacc gttttcttct aaagccgtat cgaatggctg atttccttca ttatcaggga
    40801 ttcttgcttc tgctagattg attgcgacac gttcgaacga gactgctgac cgcccacctg
    40861 cttgtccgac acagatcacg acatctggtt ggtgctgttg gatggcttct ttgactactt
    40921 gactgctttt ttcgaatacg gtcggtactt ccactttgat gatttcagca ccgctgattt
    40981 catctggcat tttttttact gcttcatagg ctggattcac tttgtcccca ccaaatggat
    41041 caaaacctgt tactagtact ttcatctgtt gttcctccgt ccgattgatt taacatatgg
    41101 ttatctttta tcataccatt ttccttgaac agcgtaaata aaggaaacaa tagtttaaat
    41161 aacataacag atcaaactta atatattctt ataaaaaaat agtgttccac tacaatgtta
    41221 gaagaggttg cgacaattat tctgtcacaa cccctctctt ctattattta aatagaatca
    41281 tataagcaat ttggaaaact agcataaata acgcaataaa caactggttt ttgatcactc
    41341 cgtatttgtc tttcatctcc agcatcgcta caggcacgat attgaagtta gcagccatcg
    41401 gtgtcagcag ggtcccacaa aaaccgcaag tcaatgcaac cattcctatt aacgctggat
    41461 tcgctccatg actaaatacg aatggtgcac cgatcccaac cgtcatcacg gtgatggccg
    41521 caaatgcatt ccccatgatt accgtaaata tcaccatgcc aagagcgtaa atgatgatgc
    41581 cgatgttcac atttccttct ggaacgatcg tacctactgc attggaaatc actgtcccaa
    41641 ctccagcgct tgtaaatacc gcacctagag aagctaaaag cattggcaac atgcttaacg
    41701 gccctactgt gcccagcata tctgctgcat catctaaaaa tgtacttggt cgattatctc
    41761 gagaaaagaa catcaagatt agcatggctg caaaaacacc gacgcccacg ccgactaaag
    41821 cacctaaatt ggtaaataga gcaaacaaga tcgcaaagac accgatactc aaagctggaa
    41881 taaaaatttt cattcctagt ttgtctgaca ttttttccat atattctttt gatggaagcc
    41941 ggctttctcc tttgctgact ttcttagcaa ttgctggtat ggtcatcgca aagatcaagc
    42001 caccgttcac gattgccgga agccatcttc ctcctgcaat aactacccct aagaccgtcc
    42061 agaaaaaggc tgacccataa cgatgaggat tggttttatc tgttaaattt cttactccag
    42121 tgtaaatcaa tacgagtccc atcacgatat aaaggatctc cagtaattta tcgcctaata
    42181 aaatatcagg atttgtaaaa aagtccatct tattgcccct ttcctggata atatttcttc
    42241 gctaatttct tttctttaag atagaagtag acacttgcca caactaaagc cgtgatagcc
    42301 actggaactt ccactaaagc aagctgtccc aatgttacgt catatcctag atctttcagt
    42361 gttgattgga ctagcaacgc ccctgctcct ccgatgaata gtacttggcc aaagaaccag
    42421 cagacatttt ccatagctga agccatacct tttagttctt cttcatgctt aggatggact
    42481 tctaaccctt ttgattcgat ggtccccaat gccatcggta aaatgattgg acgaacaaat
    42541 ccagcaactc caccaaaact cacgttaaaa gccgcaaaga tcattcgaaa gatcccataa
    42601 atatctacaa tcataccagc agatactttc ttgaatcgct tgatcaagga agccgctgat
    42661 tctttcagac catttctttc aagcgttcct gttgccaaca taatgatgat aaaaatcgcc
    42721 atcccgcgat tgtttacaaa acttgtacct aaaagttcta acattccttg aatgccaaga
    42781 ccgccagtca aagctgtaac aactaaagca accattacga tcaatatcga gtctaattta
    42841 aatgcaaacc cgagaataac aatcaagacg cctaaaaggc taagataatt ttccatatat
    42901 tttcctccat aaaatgacaa tattttttta attataaagc aaaacacata aaaaatatag
    42961 ttgttttctc acgaaataga cactattttt aaatattttt cgttattttt ttattatata
    43021 attcacctta cttattgtaa gataaagctt tttttaattt attgcctgct aatatataaa
    43081 aataaggtct agttactgtt tttttaaatg attaataaat aacaactcct ttctatgaaa
    43141 ttgcaaagca ttcatcttct tttctgctaa cgatatatcc gtcaatgctt gttacacttt
    43201 actaaaaagt atgagattgc cgatatctgg ataggtgtgc tatactacag aaaaagatat
    43261 acgatctgcc accgggtagt aaaaaagagg atgatcattc cattaggtct ttgaagggat
    43321 gattctcctc tttttgtgta ttttttatat tgaaggagga acgtatgtat ggcatggatg
    43381 gaattaatca tagcaggaat tttggaagta ttctggtcaa cgatgatgaa atggagtgat
    43441 ggtttttcta aaatcaatta ttctttttac acagtgattg gaatgattgc tagtttttac
    43501 tttttgtcaa aggcaatcaa aagtttgcct atgagtctct cttatcctat ttggacaggg
    43561 attggcgcag ttggttcggt cattattggt gtggtcttgt ttcatgataa gctgaatctt
    43621 tccacttggt tctttgtcgg gttgctgctc atcagcatca ttggcatcaa aatcactagc
    43681 ggtcactaga tacttagaca agcagacaag gactgatcag aaaaagcggg gctttttatt
    43741 tgatattcct ctttctatga aaaaacaaga aaataagact aatgacctag cgacttctct
    43801 actcatcagg tgtatgcttg tactatctat agaaaaggag tgaatatttt tgaaaagtct
    43861 ttcggtccaa gaattatcca agaactttgg tcacaaacaa gccctcagcg atgtcagttt
    43921 tagcttatct cctggcaaaa tcgttggatt agtaggtcct aatggcgctg gaaaaacaac
    43981 gatcatgaaa gctattttag gactgatcca ttactcagaa ggaacgatcc gtattggtga
    44041 aaatgagatt tctccctcta gtcataaagg attagaacaa gtaggagcat tgatcgaata
    44101 tccgggtatc tatccattct taacaggtta tgatcatctg aagttattct ctgaaacaaa
    44161 cgatgtatct gctatcgaca ctatcgtgaa acagctcaag atggaaaaat acattcacaa
    44221 aaaagcgaaa tcctactcgc tgggaatgaa acaaaaattg ggaattgctc ttgccttact
    44281 gaaccatccg tctatcgtta ttttagatga gccgatgaac ggtttggatc cacaagcaac
    44341 aagagatgtg cgaaaaatca ttaccgactt ggctactcag ggcacctctt tcttgatctc
    44401 cagtcactta ctcagcgagc ttgaaaaaat ggtcgatgag ctgatcctga tcaatcaagg
    44461 aaaaatcatc aaacaatgta caatggctga attgaaccaa acagcgcaag atttcatcgt
    44521 tatctctacg acaaatgatc aagctgctcg aacgatcttg acagacgctg gatatccctt
    44581 ggaagatcct gataaaatca agcttctaaa aaaaaacgaa gagttattag gaactgttat
    44641 ccagttattg tctgcagaaa atgtccatgt gacagatgtc cagcatctga cgaatgattt
    44701 ggaatcttcc ctattggaaa ttctggattc agtaaagggg gaagaagaaa aatgacgttg
    44761 cttataaaac aagaattatt taaattgatc aagaaaaagt caactgctgt tttatctgtt
    44821 ctattagttg ctttgctcat aggaacagca cttctagcca aaaaatacac gacgatcatt
    44881 gatccagttg aaatgactgc tcagcttttc agtgccacat cttggattgt ctttatcatg
    44941 attgctgctg caagtacgat catttcaatg gaatcacaat atggtacatt gaaaaatctc
    45001 ctttatcgaa agtattctcg aggagaaata ttagtaagta aatggatcac attagttatt
    45061 tattctattt atttatacct tttagctatt attgtcaccg tgctgatgaa actgatcctt
    45121 ttcccttcga tttcctttac ggagaagatt tctactggtc agacactgat ccaaagctta
    45181 ttcacttata ctttgggtag ttatatcggt ttatggctaa ttttaagttt agtgttgatg
    45241 attgcttgtt ttatcaatag ttccggtgcc tccatctcag cagggatcgt cttttatttt
    45301 gcttcatcaa tcatatctgg tatcctcatc gcactcattc aaaaatggga gtggatcaaa
    45361 tggaatccaa tcagtatgct gaatctgcaa aaccaaattg gcaacgaaga gattatgaag
    45421 caattgactc atctttctac taatcaaatg ctgtttggca atttagctta cattgctttg
    45481 ttcttagcat tgggatacct cgtattcaag cgaaaaaatg tatgatggtt cattaacaaa
    45541 gaagttgtga cagaagtggc cagtttcaag aaatttcggc ttatttttag aagaagctac
    45601 ttcttgaaca ccatttattc aaaaaaagaa gcgatgacac gaatgttgtc accgcttctt
    45661 ttttgaataa accacaggct tcacagcctc tctttatact tctatacgtg aagcatccca
    45721 gtggcaaata aaaccattgc gattactccg accatcgtca caccgataag taaaatctta
    45781 tctaagtgga tatgttgtac aggttcgttt tgttctttac gtgctttgag gtaaaaataa
    45841 atacctggta agaaaagaac aagaacaagc atcacttcat taaaggctac aactagcatg
    45901 gcccatactt gaaaagcact tgctaaaaac cctactaaaa attggaccca ctctttccgc
    45961 tgataagaaa gcttcatttg gtacagccct aagaaaagcc acgtgaagaa aatcgctgct
    46021 gtaccaagtg tataagcaaa gttatatgca ctgtcagtga ataataatga aagtaaaaag
    46081 acattcgtac ataacgtcgt caatacgata gcataagttg gtgccccatt tttgttgagt
    46141 tttccccatg ctttaggcaa aagtccgtcc tcagccatat tccccattgt ttcaatcggc
    46201 aagattgtcc atgagagcca aaccccaact aaagaaatga tcaaaccgcc gttgatcacg
    46261 accgcccccc atttaccaac catcatttca aatacatatc ccatagcagg ttgcgctttg
    46321 atcgtttgca gctgattcat cgtcattgtg ccatatggaa gcatggaaac caagacgtaa
    46381 ataatgatca aaccgaatat tcctagaatc gttgctttcc caacatccga ttgttttttt
    46441 gctcgtgaac ctacgacaga agctccttca ataccaacga atacccagag catcaccatg
    46501 atgcaactca atacttgact agaaaacggg atcggctgcc cattcgcatt caatatgata
    46561 tcgctagaaa agttattaat gaattgttgg atcgaaaagg tgctgatagc tactacaata
    46621 aataaaaata atggcactaa tttacaaaat gtgacgatag cattgacaaa gctagcattt
    46681 tcaactccac gattcactag ccatgcatat ccccataaga agatcgtact catcacgatc
    46741 gatgccacat tttgaccacc ttcgaatacg gggaagaaat aacctaatgc actcatcaac
    46801 aatgttgcga acgccacgtt tcctaaccag catgtgagcc agtaacccca accgctgata
    46861 aaaccagcga aacggccaaa accttcttct gcgtaactaa agatcccgcc ttttaaatct
    46921 ggacgttttt tattgatatt attgatcgat aaggagagca tcaacattgc tgttcctacg
    46981 agtacccagc tgaagatagc tgggccacca gccgatccgg agatgtccgt cataatacca
    47041 aatacgccac ctccaatcgc tgaaccaatc actaaggcag caagtggaat caaaccaatt
    47101 ccttttttct gttgctctgt atccatgtaa gcatcctcca aagtaaaacc gcttttatca
    47161 aaaagtataa caaacctttt ttatttttac ttaattaata aaaactttaa tagaaatata
    47221 attctaccga cttttttctc attatacaag caaagcgcct agtccctttc caaattacac
    47281 caccaaaaaa acttaaaaag atgctatact aaagggaaag aattggggga tgatccatga
    47341 acattttata tatatcgatt tcaggaaata cgcgtgcttt tgccaaacat ctagcagaat
    47401 atgctgaaaa aatgcatgca gaagatcctg tcaatcctga agttacttta aaagaaatcc
    47461 atgaaaatag tgattttacg aaagaaacag aaccattttt tactttcgtt cctacttatt
    47521 tagacggcgg gaatgggtta gacaacggtg acacagaaat cttgaccgaa acgatgcgcg
    47581 aatatctgga atacgaagac aatcataaac tttgccttgg tgtagtcggt agcggtaata
    47641 aaaacttcaa caatcaatat tgtctgacag ccaaacaata cgcacaaaga ttcggctttc
    47701 ctttcttggc agattatgaa ttacggggaa caccatctga tgtgacacgc gtttatcaaa
    47761 ttttggcaga aaaaaataaa taacacaaaa gaagaagctg aaaaataaat ttcggcttct
    47821 tctttttatg ttctctattg tttctattct tattaagctt tgacatccat cacaggtgct
    47881 tttgctttcg ctttacctgt tttttccaag acaaagtttt ttacacgatc catattggtt
    47941 accaagacga tcatggaggt ttctttgtct gctgctttga ttgcttctaa gtcagcttct
    48001 gctacaagcg tatcaggtgt cacttgctgt ccttctgtta ctttcacatc gaatggcgta
    48061 ccgcctaagt caactgtgtt gatgcccatg tgaagcaaga tttctaagcc atttggtgtc
    48121 gtaatgccga tagcatgttt tgttgggaaa acagaactta ttactccagt aaccggggaa
    48181 tagatatgtc cgttttctgg ttctacaaag taaccttcac ccatcatttt ttgtgcaaaa
    48241 actgggtcac ttgctttatc taaagaaaca actgttccgt cagcaactga tgataagata
    48301 gtcacacttt cagctgaagc ttgaggtact gctttttcag gtacttcatt tactgtggct
    48361 gtttcggtcg ctagttcttc tttttctaaa cggtctttag gaataccgaa gaagaatgta
    48421 gcaacgaagc caccagcgta agcagccaat aaaccaagga tatagcctaa ccatttacca
    48481 tcagagatca atggaatcaa agcggctcct gaaggtccaa tagcgattgc tccgacattt
    48541 ccgatcattc cgatcactgc cccaccgata cctccaccga tacaagcagt aataaatgga
    48601 cgtcctagag gtaatgttac tccgtaaatc aatggttcgc cgattcctaa gattccgact
    48661 ggtaaagccc ctttgatcat ttctgttaat tctttgtctt ttttgcagcg gatccataat
    48721 gccaatgctg cacccacttg tcctgctccg gccatcgcaa ggattggaag caataaggta
    48781 cgaccagttt catcaatcat ttgtacatgg attggcgtca agatctgatg tagtccgaac
    48841 atgaccattg gcaagaataa tgtacctaga acgaagccgg caaatgctcc tccaacacca
    48901 agtacccagt tgatcccacc gaccatgccg tcagaaatga accctgctaa aggcatgatg
    48961 aagaaaattt cgatcagacc gatggcaatc agggaaagag ttggcgtaac gatgatatct
    49021 accgcatcag gtactacttt atgcagtttt ttctcaacga ttgacaataa ccaaactgcg
    49081 aagataacac ctaagatccc gccttgtcca gttgcaagag cttcaccggt aaacaagttt
    49141 ttcagtggtg cttctggatt catccctgtc agcatcacaa cagccccgat aactccacca
    49201 agcgttggcg ttgcaccaaa aacttgtgca gcattgatac ctgtatagat aactagatag
    49261 ctaaacatcc cgtttttcaa gatgttcatc acatcgatat attgttgcca tgttcctgcg
    49321 tctagtgttc cagctgtgac taagtttgct aaaactgcgg caatccctgc cacgatccca
    49381 gtgccgacaa atgcagggat cattggtaca aagatattag agatgtcttt taataccgat
    49441 ttgattttag agggtttttg tttcgatttt tgtgccgctt tcatttcttg tgcccgttcg
    49501 tttacacggt cttttccaga tgcagaagaa cttgctgtag ttgcactagc agaaggaagt
    49561 ttttctccta atttcacgcc tgctaagtca accatttcct gcgctacttt gttcactttc
    49621 ccaggtccga tgatgacttg gagctgttca tcctctacta cgccaagtac tcctggaatc
    49681 gcttttaatt ccgagacatt tacaagatca tcattgatga ccttcatacg tacacgagtc
    49741 atgcagtgga caatgctttc aacattgccc ataccgcctg ctccttgata aatttgtttt
    49801 gccagttctt ccaaagtcaa ttcgtttttt gccatggtct tttccccctc ataaggttcc
    49861 ttttacaaaa ccgtttgctt cagctaattt tgcttgagct gcctctttat cactatttgt
    49921 caaaatcatg acgatagcca gtttgacatt ttgatctgct tcctcaaagt acttttcagc
    49981 tgtttcgtag tcagcttctg tcgcttgcat gatgattcgt tttgagcgtt caattagttt
    50041 ttcatttgtt ggtttgacgt cgaccatcaa gttattgaat actttaccga taccgatcat
    50101 actgatagta gaaatcatat tcaaaatcag tttttgtgct gttcctgact tcaatcgagt
    50161 agagcctgtc aaaaattctg gtcctgcatc gacttcgatt gggaaatccg catgctcgct
    50221 gatttctgct tgtttattgc aagaaatcgt tcctgtaaca gcaccaatcg attttgcgta
    50281 atctaatcca ccaatcacat atggtgtacg accgctagct gcgataccaa taactatatc
    50341 attttttgtt aaattcagct tgattagatc ttcttgccct aattcataag aatcttcggc
    50401 tccttcgacg gctacagtca ttgcttcttc tccaccagca attaggccta tgaccatttc
    50461 cggttctaca ccgaatgtcg gtacacattc agcagcatct aatacaccaa gtctaccact
    50521 cgttccagct cccatataaa tcaagcgacc acctttttta aaggattcaa tcgtgttggc
    50581 gatcactggc tcgatacttg gcagttcttt ttcaacagca gcggccactt tctgatcttc
    50641 tttgttcatg agttggactg cttgagaaat actcatttca tctaatccaa aagtttcttg
    50701 gtttctgcgt tccgttgtta ggttctctaa attgattttg ctcattttta tcttccttct
    50761 tttcttataa attgatagtt cataccagct ttgatttggt tgatcagcgg tagttcttct
    50821 ttgatgactt tggctactac attcactttt tcatccgctg gcaaatcata tttagttaat
    50881 tggatctcac ccatatagcg caaatacttt tcgttatcta aagtaataga tcctttcata
    50941 cgcttagctg tatttcttac tgggattggc ggaatctctc gaaaacgcgc atctgcgctt
    51001 cgtatgacat ctcttgcatc atcttgccga ttcgtatgtt ttcctaatat atattcgtaa
    51061 aaaacttcat ctacaggttc cgtatggagc aagactgtct gttctttttg gaaagaagca
    51121 aattgctcct gaacgtgttc tgacagacct gcatctccga tataaacaat atccgtgtta
    51181 cttgctaata gatcaagagc acctgccaga ggatggatcc ctcgatgttc ttccaaagtt
    51241 ggtaatcctt gatacagtgg acctctcaac tctgtatctc ctggtacaaa gccttgtaca
    51301 aggaatcctt gagttttgag ccattgattt ttttcctgat accattcttt gtccaaccct
    51361 gtttcaagac gtggataata attatgccaa gcttcaatct gtgagaaatc agccgctgct
    51421 tctttcaact catcgatatc attaggcgtg atcgtgctgg cattcaaact gattttcaat
    51481 tgatgtgacc agtcggcgat ctgctgatta gaaatatgat aatccattct taaccctgtt
    51541 acaccaattg ctttcaaggg tgttagatct tctaatgaaa agccagctcg tttcaatgcc
    51601 tctcctgaaa tatcgaccat caactctagt ttattctttt tcgcttcgct tcctagttcg
    51661 atcaatcgat tttgataagc cgaaacatca tcttccggta tatgcatgga agtgaaaata
    51721 ccgacaaagc cattggatgc catttggcgg atatactgtt tcttctcttc tgacaaagaa
    51781 tcattcataa atattgaaaa gccaaacata ttatccctct ttttctgtat ccgtcttcat
    51841 ttctatgact agagtatata tctaaagaaa caaaatttca atacttttgt taaaataatt
    51901 aaattttatt tctaaaaatt ggatttataa tgccaaaaga attgacacag ccacaaaaaa
    51961 ggcactgcta agcaaaagca gtgccttgaa acattttatt taaataacac aaaagtctaa
    52021 ttactcataa gaaattaatt ctgtattgtc taccatgaat gtaaagaacc cttcattagg
    52081 cattggatga aaataagcat tgatcactct tatcaaggca ttatgacaga ctaacaagta
    52141 gacattttct tcgtcttcca tgcattcttt caataaagga acgatccgtg cgtacacatc
    52201 taagaccgac tctccatttg ggaaacgtac agcaaacgct aaacgcgctt tttgaaagtt
    52261 ttcatctttg cttggcagtc cgtcataatc cccaaaatcc atttctacca atcgctcatc
    52321 agcggtcatc ggcaaattga gacgatcaac tactgcttgt gctgtatctc ttgctcgttg
    52381 aagaggggaa tggatgattt tcgtgattgg aacaggcaaa tctactacct tttctgctag
    52441 tgcctgtgcc tgcatctgtc ctttttcagt cagcggcaca tctgctcgcc cgcaaactaa
    52501 tccttgtgcg ttccaagttg tttctccgtg tctcgttaca taaagcatgt gattctctcc
    52561 ttcgttgaca aagttctcct taaccatacc ttgttgtctt tgagattaca aggtttagat
    52621 tttctcaaga gaaataatct cagtagatac tttatctaga aaggtttgat catgttccac
    52681 tagtaacata gcaggtttca cgttcaaaat cagttgttct aattgttctt gattgaagac
    52741 atccaaataa ttcaatggtt catcccatat atagagctca gctggttggg ataaagattt
    52801 agccaattcc acttttttcc gttgtcccat actcatctgt tcgattttat tatgaaaaac
    52861 atctctttcc atcccaagct ttcggagatt attcaaaaat gcttgatagt ctactcggtt
    52921 tttcttcgcg aattccgcca atgtccctcg attgtcttca taattttggc gtacgtaact
    52981 aatggtcaaa tgtttgggct gggatttttc tcctacaacc ttgccgttga atgtccccag
    53041 aagataatgg ataatggatg actttcccgc gccgttagga cctgaaattg ccatccgctg
    53101 atgaggttcg atcgtaaaat gaactggctc gaataacaga ttttcatacc ctaattgaag
    53161 attttctacg cttaacagcc gtttatgatg agacacttgg ctattcatcg tcaaagcatc
    53221 gatatactcg atatctttta ataatttttc tttctcactg atctgggttt ccatccgatt
    53281 cacgattgct ttagatcgtt tcatcgtccg tgcagcatca gcgcctactg ctcctttatt
    53341 cactcgccta gattccgtat cgatgaatcc gacttttttc tttgttttgt ccccttctcg
    53401 ggaacgagac cattctgctt tttcagctgc tgttttcttt agcctgctga cttctttttt
    53461 caatttttca tttttagcta tttcaaattc atcacgaagt tttttctgtt cttcatagat
    53521 agagaaattc ccttgataaa gttccagttg gctcttttcg attgctaaaa catggtccac
    53581 tacttcatcg ataaatcccc gatcatgact caccacgatg aatccttgtt ttttcttttt
    53641 caagtaagcc gctacttgtt ttctgccaga gatatccaaa tgattcgttg gttcatcgat
    53701 taacgggaaa tgagtgtcat ccacaaataa gagtgccagt aggacttttg tcttctctcc
    53761 tcctgatagt gtgctgaatt ctctccataa gatttcagga tctgtttgca tcagttggag
    53821 ctctctttca atttcccata tctcaaaatc cataatctca tttaacacat aataggtcaa
    53881 acgctcttta tcttttgttt gctgcgggaa atagacaaac gcttgctgat ggatcacttg
    53941 cccttgataa gggagtttgt tttgcaggat attcagtaaa gttgtctttc ctcgaccgtt
    54001 tcgtccgata agtcctagtt tccattgtgt gtcaaagttt agattggctt gttcaaataa
    54061 taatgtgcct tggctgtcat agccgaatgt cagatttttt atttcgattt tagacattat
    54121 tccatcacct cgtaaaaaaa gaccagtcct attttcagaa ctggctaaag aggatgcaag
    54181 ggttggggca cacaaaaaga cccatacatc gaaagaacca agccaatccc gaaaatctgc
    54241 acactgctcc cttgtctcca caaggtacag tctgaatgca gctttcatca atcgacttaa
    54301 tttttcaatg cacggatccc tcactttgtc ctatatttga aattacgata gcataaagaa
    54361 attgtttttg tcaactactt cgggagaatg ttgaaaaatc tgctgagtgt ctgtcctaag
    54421 atttctgttt tttctaatgt ttgcctgtgt tccattgctt cctctaaatc gattggtcct
    54481 aattgaatgc ttaagacaat ggggagaaaa tcaaagagtc cttccagctc tcggtctcta
    54541 cttccgcaaa tagcgattat tggttttcga tatttttttg caagcactgc tacgccatat
    54601 ggaacttttc cgtggattgt ttgctgatca atccgccctt ctcctgtaat gatgacatcc
    54661 gcttgttcga tctgtttttc taatccagtg atttggctga ccaactcaaa accagagacc
    54721 atcttcgctc ctaacaaaaa aagggctccg ccaataccgc ctgctgctcc gcttcctggg
    54781 atgtcatcta aatccacctc ccaaacatct tttatctgct gagcaatctt ttcagcttgt
    54841 ttatccaaga aagctaacgt cgtatccgtt cctccttttt gtcttccaaa ttgccaagca
    54901 gctccttgtt gacctgtata tgggttggtc acgtctgcag cgatgatcac ttttacttta
    54961 gaaacaagaa cgttccttcg atccaaatga agttttctag tagataacaa aggatttcct
    55021 tctgtgtacc cttctaaaga agcacccaaa gattggagta atcctagacc accatcgcta
    55081 catccgcttc ctcctaaagt gacaatgatt tgttccactt cttgaagcag tgtatctttg
    55141 ataagctctc ccaaggcata actagaagca agtcggatgg tttgatccgt tggtttatca
    55201 agtaaatcta atcctaatac ttgtgcagat tcaatgactg cggtattttt tccttgccag
    55261 ttcgtcaata aataactgat ttttcgctga cgaaataaga gatccatccc atcaatcgta
    55321 cgccaggttc ccccgagcgc gtaatagatt gcttctgcag tattttctcc gccatctgca
    55381 atcggcacat tgatttttct tcctttacgg tcttcccaac catttagaac tgcctgattt
    55441 aattcaaatg aagaagcact tcctttaaat gaatcgattg ccgccaaaat atccatctat
    55501 atccctcact ttcttcttaa gtaagacact ttttttcact tttttcaaac aaaacaatgc
    55561 tattttcttc tgtttttcta tatactaaaa gggaactcat tgaataaagg agagaaaaaa
    55621 catgaaaatc gcaatagctg gagccggagc aatgggcagc cgaatcggat taatgttgca
    55681 tcaaagcgga aatgaggtcg tcttgatcga tcgctggcct gctcacattg aagccattcg
    55741 tacaaatgga ttgattgctg actttaatgg caaagaagta gttgcaaaac tgccaatcta
    55801 ttcaccagaa gaaatcatcg aaagcaacaa acacgtggat ttgatcgtag ccttgacaaa
    55861 agcgaatcaa ttagatgata tgtttcgttc gatccaatcc attattactg agaatactta
    55921 tgttttgtgt ttactgaatg gattaggtca tgaagatgta ctggaaaaat atgtaccaaa
    55981 gaaaaatatc ttatttggga tcacgatgtg gacagctggt ctagctggtc ccggaaaagt
    56041 cacattatta ggtgatggag aaatcgaact agagaacttg gaaccagaag gcgaagcatt
    56101 tacaaaaaaa gttgtagaag tctttcaaga agcaaaattg aatccaatct atagtcataa
    56161 tgttcgttat tccatttggc gaaaagcttg tgtaaacgga acattaaatg gattatgcac
    56221 gatattggat tgtaatattg ctgaattagg tgcgcaaaaa gcggcagagg gcatggttcg
    56281 aacgattgta tctgagtttg cttctatcgc agcaaaagaa ggaatcacat tagatcaaga
    56341 agaagtgtac caacatattg cttctactta tgatcctgac aacatcgggt tgcattaccc
    56401 atctatgtac caagacctga tcaaaaacca tcgtttgact gaaatcgact acatcaatgg
    56461 tgccgtttgg cgaaaaggac aaaaatatga tattgctaca ccatattgtg cctttttgac
    56521 ccaattagtc catgcaaaag aaggaatcct tggcgcagaa taaaaggctc tctgatgaga
    56581 atcagctgga tcagcagctg gttctcattt ttttaccccc atgaaagttc aaaaagaaaa
    56641 acacaattct catgttgcca taagaattgc gcttgtttat tttcatctat gattggttgg
    56701 cacttttatt tatttttaac agaggaaaga tcgtattcat attgttcata aatagcggag
    56761 tcagtagtga aaaaacgttt tgcccaattt tctgcatcaa aaaattccaa cagttctgat
    56821 gggattggtt gaaatggcgt atgcaaaaat tccggtaatt catctaaatc acgttcttga
    56881 agcaaaaaaa tattttcaga atgataaaac tgataatgag ctatggcttg attatctgtc
    56941 actagtttct tttgaaaata catagattca aacgttcgca aagtcactcc ttgctgccct
    57001 tcccgcaaca gttctagaat ccccctcgat tccccggttt ttttcagata ttcttcataa
    57061 gtaaggtatc caggttgttc atttcctcga agcggaagaa taaagtaatt ggtcgtaaca
    57121 cctctttttg taaattcctg cttatatttt tctgcccgtt cttttctgcc gttatttgtt
    57181 gcaccaaaaa atagatccgt ctttggttcg ctagaagaaa aatccatatg tttcgaataa
    57241 aaggaactat tatgttttag tccaagttct ttcgcttcta aaaaatcaaa atgataaatc
    57301 tcatcgattg ccggttcatc ttgtgcctgc ttcagcatcg cctcgtgttc tgctttaaag
    57361 tggttccaaa aaaataacac gatttttgca ttggtaaatg gacgcacgcg tcgagccatc
    57421 tccatatcaa atccataatc taaaaaaacg atcagctgat aatttgccaa ctgttgtcga
    57481 gctgatttaa tgaattccga ctgtagtaaa tcttttccgg accaaacatc taaagagcgg
    57541 atggaaggaa aaaaataaag tgatttattt ttcgcaatta gcaatacgtc gtttttgttc
    57601 atctgttccg cctcactttc tctgtcactt tttcctatga tagcctgttt aaatagtaaa
    57661 aagccagtaa aacgcttcct attattttta taaaaattta acatttctat gaaaatacga
    57721 tgaaataaat cattcttcca ttaaaatatg cccaaaagtt ttctgaatag ttgtaattat
    57781 ctgaaaattt gttatcatta gtcattatta ttattactat ttattcttac tatttattct
    57841 tactatgcat tttgattgtg aatttaaaag aaagaggtta tttatggaag ataaaaaatt
    57901 gaaaaaacaa cttagctccc gacatatcac catgctagct ttaggtggag cgattggtgc
    57961 aggtctattt aaaggaagtg gcgaagcgat tggaatcgcc ggcccttctg tattgatcgc
    58021 ttttttgatt ggcggcataa ttttatatat cgtgatgaaa ggtctgggaa aaattgtttt
    58081 aagtggtggt gatacgcacc acggattatc tggattgatt cgtccatatc taggtgctca
    58141 tgctgccgat tttaccgatt gggtctactg gtccatgtgg attatcaata tcattgctga
    58201 agctgttgca gctgcttcct ttttacagtt gtggttcccc cacatcccag cttgggtatt
    58261 tgtttttatg ttggctgttt taactactat catcaatctt tattcggtac gattattcgc
    58321 agagacagaa tattggctgg cctttgctaa aatcagtgtc attatcctat tgatcatttt
    58381 tgctgcttat cttgtcggtc agcaaatgtt gggtactggt gttttcccta cccttcaaca
    58441 attaactgat catggtggtt ttactcccca cggtatgaag ggaatcatca gttctttgct
    58501 tgtagttatc tattcttacg gcggttctga gttgattgct atcacagtaa gcgaagcaga
    58561 tgatcctaaa cgtgcgattc ctaaagcaat caaaggcgtc atgggaagaa tcatttcctt
    58621 ttacattatt cctttatttt tgcttttgat tatttttcct tggaatactt tagcaggcac
    58681 gaacgttagt ccttttgtga tggtatttga aaaaatgaat attccatttg cggcagatat
    58741 cgtcaatttc gtgattgttc ttgctctgtt ctcgtctatc aattcaggtg tatatgcttc
    58801 ttcgagaatt ttgttcttcc gcttgaaaga tcggaaaggt tcctctagaa aactagctgt
    58861 tttaaacaag catcaagtac cgcaacgtgc tgtgctgttt tgtaccagtg ttctttatct
    58921 aggtgtggct ctttcttatt ttgtcggtga caaattattt ggctatctgg caggttctct
    58981 ttcctataca gtattattga tctggatcat tatcagtgct gcgtcctttg tactgacact
    59041 aaggaaagga acgttatggg acaaaggaat cagctttttt gcattagcag tcttatggtt
    59101 gattttcctt ggtatcctat tcacgaactc cattggggta actgtattga ccggtttgct
    59161 ttacctgttc atttatttca gttatcaaaa aaagaatgat gctttcgtct tgacgaatga
    59221 atgaaaccaa tagagaattt tattctattt atattgaata tctggagcta ttgaaaaaaa
    59281 ggagctgcga caaaaattgt tgcagttctt ttttccgaat aaacggtgtt caaaaaccat
    59341 ctgtgcagat taattgattg ttctccacgc tcatgacatg atagaagaaa ggaatgaaga
    59401 aaaaggagtt tgttttaaat gaaaaagtat tggaagtttt tgttgatgat tggtgtttcg
    59461 acggtagtca tgtttggtat gatgtatttg aatgtttatg cgcttgatca tatcttcttc
    59521 agtcgcacac gtgtattcat ggcgttgatg atgggtgcag tcatggcagt catcatgttg
    59581 ttgttcatgt ggaaaatgta tgaaaacaaa aagataaatg ctatgatttt agccgctagt
    59641 cttcttgttt ttgccggttc cttatttatg gtacgaagcc aaacaactgt caacgatacg
    59701 gcgtggatga aggcgatgat ccctcatcac tctattgcta tcttgacaag taaacgagct
    59761 gatttaaaag atcctgaagt aaaaaaatta gcggaagaaa tcattcaggc acaagaagaa
    59821 gaaatcgaca aaatgaaaaa aatgatcaaa gaaatggaat gaccattatc catccaaata
    59881 aaaaaagagg atgttccaga agtgatcaac ttcaagaaat aagaagaagc tacttctgga
    59941 acaccgtgaa tcagaggttg tgaaaaagct gccctgcatc aagtaataag aacagccaaa
    60001 caaaaatagc ttctcatatt tttcgtttgg ttaggcttat taccgcaaat gcaagctttt
    60061 gaacaccgtt tattcgtaaa agggagtgtg acaaaagtct tgtcacactc cctttttacg
    60121 tttttattgt tctaattgcg ctgtcttgct tactgcttct tgcggtttca caaatttctt
    60181 tgagatcccc caacctgtaa aggcactgac catcgaaaac acaggtgaaa gcaaactgaa
    60241 aaacacgaat ggcaagtaag tgagtgtagg aatgccaaat gtacttgcta cgaaacttcc
    60301 ggcgattccc caaggcacta agtagttgat tactgttcca ccatcttcta gtgttctccc
    60361 taatacagtt ggatcaaatc ctgctttttc gtaagtttct ttaaatgcat taccaggcag
    60421 gataacagat agaaattgtt ctccaataaa gatatttact ccgatgcttg tcatcaatgt
    60481 tgtaaaaatc aattttgggg tgttcgtcat ctttcttgat actcgttcca taacggttga
    60541 gatcaaccca aattcgatca acaaaccacc taatgacaat gttagaataa tcaatgacac
    60601 agttggcatc atgctttcga ttcctccacg gctaagtagt gaatcgattt gttggtttcc
    60661 agtatttgaa acaaatcccg attcgatgac ccctgccaac ttcgttaagg aagtttgtgg
    60721 gttttgaata aagatcattc ctactgctac agcaatattc aacaaaatcg tcaaaattgc
    60781 cggtaccttt ttccatgcac acaagagcat taaaaataga ggaatcagtg accagatcga
    60841 aatagtaaag tttgcttcta aaatatcagt cacttcacga atagatgaaa gacttgcggc
    60901 tttacttgtg tgtcctaaaa tcatgaataa aaagaaagaa acaacaaatg ccggaacagt
    60961 tgaccacatc atatgcttga tgtgtttgaa caaatcggca tcaacaatag ctgctgctaa
    61021 atttgttgat tcggataatg gagacatctt gtctccaaaa acggcacctg aaacaatggc
    61081 tccaacaaca agggctggat ttagtcctag tgttgtccca ataccgaaaa atgcaatccc
    61141 aatcgttgac ataacagtaa aggcactccc tacagcgcta cctacgattg cacaaacaac
    61201 aaatacagaa gggacgaacc actggacact aatcaattta aatccaatga ccatgagggt
    61261 tggaataatt cctgcttgta tccatacagc aatcaatgaa ccgactaaaa taaaaataaa
    61321 gattggaatg atccccggtt tgatgccatt gatgatccct tcgtgcagcc aatctgtcgg
    61381 gtattttttt atcactgcgt acaacatgac cattccgata gctgccaaaa tcgtgatatt
    61441 aggtgaaacc tttaatccga caacgccaat cgcaatgcct aaaacaatga ccatcaatac
    61501 aagtgttgct tctaaaaaac ttggtgttcc ttttttttcc atgataatct ctcctttttt
    61561 agttgttctt atgttctaaa aaagttaaga tatcggatta ctccgccaca attcatccgc
    61621 gattcctcct ttataaaaat aaaaagacct gctttcaact aaggacgaat gactccgcgg
    61681 taccacctta attaaaaaca gatctgtttt tcactttcaa acgattattc aaatgtatgg
    61741 actttccatg taattcgtca attaggcttg atcggttcac agcgaccacc gactttctga
    61801 acaaaacacc taaccactac tgcgtgaaaa gttgacttgt atgaagttta ccttccataa
    61861 gatcatttgt caatgaaaaa gaaaatattt tttcattttt ctgaaaatta tttttataac
    61921 tttcgcgcac aactttatct ttttactaga aagtagcgcc ctcttgtttt tttcttgcta
    61981 ctatttcttg atgttcttgt ttgatttttt ctaatagctt gggttctctc aataaatcta
    62041 gagctgtatt ggcaagtaat tccgctgcaa tcgcaataga agcaagtcct ttttcacttt
    62101 tagcagcagc tttgaattct tctgtatgtc cggcaatata tgtctcagag attgctacag
    62161 taggctgtat cgttggaata acttggctaa catttcctac atcagaagaa cctagacttg
    62221 ttctttgttc cgtttctatt tcttcatcag gaacccctgc ttcttttgca tgttggaaga
    62281 ataagtcatc gaaagaaggc gttacgatga catcatcgac tgcattttgg aacaatccaa
    62341 actcaaaagt cgtacccgtg cttaatgcag cacctcgtac gatattttcc actttttcat
    62401 atactttgtc taatgtttgt cgatttcctg cacgtaaata gaaacgtcca gcagcgtagt
    62461 ctggtatgac attggccgcc acgcctccat ctgtaatgat tccatggata ttgacatctt
    62521 ttggcaattg caagcgtaga gcgttgattc cgttaaacac ttggatcaag gcttccaaag
    62581 catttactcc tttttcaggt gctgctgctg catgagaagc gacaccgtaa aatttgatat
    62641 cgactggatc atttgctaaa gattctgtcg ttttcccata acgaaaagct ggatggacac
    62701 ataatgctgc atcgacatcc tcaaaaaaac cttcccgaac gaagcttccc ttagctgatc
    62761 cattttcgcc tccttcttcc cccggagtac catacacacg aatttctccg ccaatctcat
    62821 caatgaattg tttcactatg ctggctgcta atacggagta agtaccaaat aaattatgtc
    62881 cgcatgcatg accaatacct ggtaaagcat caaattctgc caaaaaggca attgtcggac
    62941 ctggtttatt ggaaatataa cgtgcatcaa agcctgttcg gtgcccagct acttcttttt
    63001 ctacccagaa cccttctttt tccaattgtt tgattaaagc tgctgaggaa taaaattcat
    63061 aattacttac ttcaggatgg tcgtggatag ctagtgcaag tgcttgatat tctggtaaac
    63121 ggtattgaat cagatccttc aattgatttg ttgagagtgt ggttgtcata aaaatttcct
    63181 cctatgctag tcgttttttc ttattttctc ccgaatgttt cccacgcagg tacgcttgaa
    63241 ccttttgatg ttttttcgat tactttggct gtttcttctg tttgataggc atctactatt
    63301 ttttgatacg ttttattgtc ttcatcttct tttcttgcaa cgatgatatt gacataagga
    63361 cgtgcatgct catcgactgg ttctaagaag attgcatcag aagcgggatt aaatccagca
    63421 tctacagcta caccgctatt gatgactgaa atatctacat ctgacaaagc acgtgctgtt
    63481 tgggaagcat ctaactcaga aatgtctaga ttttttttat tctcggtaat atcagaaacg
    63541 gtaggcgctt ggccttttgc cttgtccact ttgatcaatc cagcagtttg caataacaga
    63601 agagctctgc cgccattcgt gacatcatta gggattgcaa cttttgctcc atctttgata
    63661 tcagccacat cttttaacgt attggaataa attcccaacg gtgcattaac cgtattccca
    63721 atcgatacta aatcagttcc gtgttcttca ttgtaattgt ctaaaaagaa ttgatgttgg
    63781 aaggaattca aatcgatcga tccatctgct aaagccgcat ttggctgatt gtaatctgta
    63841 aatttcacat attccaaatg gatgttttcc tttttcaaac ggtctttcac atcgtcccat
    63901 acatctgtat cttccccaat gatccctagt tttacggtcg tttctttttt ttcagttgta
    63961 gctgcttttc cttggctgca tcctgccaac caaataattg ctacaaatgt aatgactgca
    64021 aaacgaataa tttttttcat tttttctcct ccattttcaa tgtgtgactt ttttaatcag
    64081 ttgattactg ataaattgac tcaaaaaaac taagaccaga atcaataatg tagcgacaat
    64141 cgttacatct gtttggaatc gattatatcc tctcgatata gcaagattcc ctaatcctcc
    64201 ggcacctact gctccagcca tggtagtcag tccgatcaca ttgatgatcg tcaacgctga
    64261 gacccgaatg ataccaggta acccttctaa caaataaaca cgtaaaatga tgccgattgg
    64321 gctcgtgccc atcgcttctg ctgcttcgat caccccagga tcaacttcta gcagtgcatt
    64381 ctcgatttga cgggcaaaaa acgggacaac gccaaaaatc aaagggacta aagctgcttt
    64441 ggcaccaatc gtcgttccaa ctaagaaacg agtagtcaaa gctaaaagag aaagcaagat
    64501 aatgaaaggg atggaacgaa tgatattgat caacttatca agtatttcga acagcagcct
    64561 gttagctagt aatccatttg gacgtgtcac tactaacgtc acacctaaga tgattccgat
    64621 gatcccacca atgaatgccg tccaaaaaga catatatagt gtttgctttg tcgcttcgat
    64681 gaattcatcc ggaatcaaat agacattcgg caaatatgtt ttaaaaaatt cagtcatttt
    64741 agtttcctcc ttcgatgact ttgatacggt tatctaattc atttttttgt aaaatagtta
    64801 cttttacacc agatttaatc aaataatcca atgctttttg ccgctgtttg gtttctccag
    64861 ctaaagtaac gatcaaactt cctaagggtg tttcttgtaa tagctctaca ttaccgtata
    64921 agatattcgc tgttacttgg tacttgctgt aaagatgagc gattagaggt tcgttcgtct
    64981 ggttgccgat ataacttaat tccaccaacc atttatttgc aatctgatcg gcaaaagcag
    65041 catgggcact gattgtttcc aatgcttggt caaggtgtgt cgctgtccga ataaaatctt
    65101 tagtcaattc ttcttcagga tgactgaaaa tctggatgct gctacctttt tcaatgattt
    65161 tccccgcttc cataaccgct accttgttgc agatttcttt gacaacttgc atctcatgag
    65221 tgatcaggac gattgttaga cctagctgac gatttagttt ttttaacagt gcaaggatct
    65281 gaagggtcgt tttcggatca agtgcactag ttgcttcatc gcataacaac actttaggtt
    65341 catttgccag agctcgtgcg attgccactc gttgtttttg cccccccgac agttgtttag
    65401 gatacgcaga tgctttttct tccagaccga caagttccag tagttcattc actttttgac
    65461 gacgttcctg ttttgatttt ccagaatact ttagagaaaa atctacgttg tcaaaaatcg
    65521 ttcgactttc cattagattg aaatgctgaa agatcatacc gatggccttt ctttcttttc
    65581 gcaattcttt tggagagagc tggcttaaat tcgtctgatt gacgatgact tctcctgctg
    65641 ttggtttctg caacaaattc atcacgcgga ctaacgtact ctttcctgca cctgagtaac
    65701 cgacgatccc ataaacatcc cctttttcaa tcgttaaatc tacagaatct actgcctgta
    65761 tctctttttc tttttgtttg aaacatacag aaatatctcg caattcaatc attaacattc
    65821 ctccttgtct ataaaaaaag catcctcaag aaaatgaaaa tagtcatttt cttgaggacg
    65881 cctttttgcg tgttaccacc tcatgttcaa gctgtgttca cacacaactc ctcttcaagt
    65941 accatcatac tctagcaaga tatcggtcgc agccgtcacc gccttacatc tatgctcggg
    66001 atgaattgct cgatggccat tttccaatag tcgttccttg cttcttctca gctaccgaag
    66061 ctctctgtca aaggttcttc tatcgtactt accatttcaa tgcaaataat attcaaaaaa
    66121 aaaatccttt tactaacata aactatgtca gtaaaaggac gacgtatcgt ggtaccacct
    66181 tttttcggaa gtttccttcc ctcaagccca acatctcaaa aagagagatt ggcgttcgtt
    66241 ttaacggtcg aacatttccg aatttgccta cttatcgaca aattattctc caaggccatt
    66301 ttcagctttt cttacttgac tcttcacacc agccagagcc tctctgcaaa gtttccaagc
    66361 ttactttcct tctcaacgaa atcaatattt tgttgttggg aataatctac aggaggaaaa
    66421 ctgaaaagtc aagcatgaaa tccaaattat tttttctata tttatttttc tgttttttta
    66481 tctaacattt caataacagt tcgaagatct tttccttccg caagaaggtt caatttttcc
    66541 ttctcttcga cgctataatt tcgaacaaaa ctggaatcgg gaatcaaaac aacgcctagt
    66601 cctgcacgtg aagcggctgt cgctcctact aaagaatctt ccactgcaaa agctgaaaga
    66661 gcttctaatc ctgttcgttc caaagctgtc agataaggga ctggtgaagg cttgttctcc
    66721 gatacttcat ctccgaacgt aaacgtatca aagtaatcgg ctaattgaaa gtgatccaag
    66781 atatctgttg ctcttttcgt aacagttgtc gtagcaatcc ctagtttcat atgacgttct
    66841 tttaagtctg tcaatatttc ttttgcatag ggtttcaatt ggatagctcc acttgtcagc
    66901 tgttgataaa aatattcttc acgctttgct cggacttcct gcactttttc aggactgcct
    66961 gctgcctgca ctaaaatatc aaaactttgt ttccattttt ttccgcccca agcgtcaacg
    67021 atttctttcg ggatatgaat atcaaattgc tggaatcccc aaagccaacc atcccgatac
    67081 gttctttccg tatccactaa caaaccatct aaatcaaata ttgcaccttt catctataca
    67141 ttaatccttt ccaaaacaat acacctagtt tagcatgact gatccaaaat gaacagaagc
    67201 atagagccca gccgcatcac ttataagagt tcttggaatc gacggatata gattttcttc
    67261 acagctgtca caagcgccag ataagcgacg actgttataa aaaaccataa ccagtaattg
    67321 ccagggagcg gcatcaagcc taactcagca ccaaatcctg tgaatggaag gactgaaccg
    67381 acaatgattc ctaatgtagt gataaccagc atggcaaatg ttgcattgct ttggataaat
    67441 ggtattttcg gtgtacgcaa tgcatggagt actaatgttt gtgtccacag ggattcgaca
    67501 aaccatcctg catggaataa tgcgataaaa atcacttgtt gtgagctatc caatgtatgg
    67561 aaacttccac caactacagc aggacaaata acaaaataca tcaacaagta agtagtgata
    67621 tcaaaaatcg aacttgttgg accaaaataa accatgaatt ttccaatact agatgcattc
    67681 catttctttg gctcatccaa atattcttta tccatccgat cccatggtaa ggaaatgcaa
    67741 gaaacgtcat agatcagatt caaaaataga agttgcaaag gcaacattgg taaaaatggt
    67801 aagaacgtac tggcaatcag tacggaaaac atattgccaa aattagaact tgctgttgcc
    67861 ttgatatatt tcatgatgtt tccaaaagtt tctcttccag aaagaaggcc tctttccaaa
    67921 atcgtcaaat ctttttctaa aaggatcacg tctgctgatt cttttgcgat atccacagct
    67981 gtatccacgg aaataccgat atcagccact ttcattgctg gagcatcatt gataccatct
    68041 cctaaaaatc cgacagtatg cccattttta cgtaaagctg tcgtcaatcg tgctttttgc
    68101 tgaggattca attttacgaa tacttcgtgt tcttcagcta cttgcgctaa ttcatgatca
    68161 ttcatttccg agattttctc accagtaatc aattcattga tttctaggcc tacttgacgg
    68221 cacacagacc gtgtgactaa ttcattgtcc ccagtcagaa cttttacagc tacaccatgt
    68281 tcttttaaag ctttcaacgc ttgttttgtt gtttcttttg gtggatcaag gaaagcaaga
    68341 taaccaatca gaaccatgtc tgactcatct ttgactgaaa attctccaac aacgcttgga
    68401 ttggtctttt gtgcgacacc aatcactcgt aagccgtctt cattaagtga ttgtactttt
    68461 gcaagcaccg cttcttttcg ttcttttgtt aatggtgcga cagtaccacc aagatcaata
    68521 aatttagaaa tgttcaacat ttcttcaatc gcgccttttg tgatcatctg tgttttgcca
    68581 gccggatcag cgactacaac actcatacgg cgacgttcaa aatcaaaagg aatttcatct
    68641 actttttgat aattgattgt atctgtatct aaagtttctg ctgcttcatc aatgatagcc
    68701 acatctaaca aatttttcag ccctgtttga tagtagctgt ttagataagc atggcgcaaa
    68761 acacgatcat cttcatttcc ttcacaatcc atatgatatt caagaatgat tttgtcttgt
    68821 gtcaatgttc ccgttttatc cgtacataac acatcgatcg caccaaaatt ctggatagca
    68881 tttaaatttt tgatgactgt tccttttttg gccatcacac ttgctccttt gaccaaattc
    68941 gtcgtaacga tcattggaag catttcaggc gttaaaccaa ctgccacaga taatccaaaa
    69001 agaaaagctt ctaaccaatc tccttttgta agcccattga taacgataac tgctggagcc
    69061 atcaatgaca taaatttgat cagcagcatg gatgttttgt ggatgcctaa ttcaaaactt
    69121 gattggatgg gtttttcaga tagcgtttct gctacatgcc caaatagtgt gtcatttccg
    69181 acagaaacaa tgattccttc cgcgcttcca ctgatgacat tgcttcccat aaagacaaga
    69241 ttttcataac ttgtttcact ttgctgatcg tcttcacata ctttcgcatg cttttctact
    69301 ggatagcttt cccctgtcaa tgctgcttga gaaatgaata gatcctttgc ggacaataaa
    69361 cgcatatccg ctggtatcat atctcctgct gaaagccgaa caagatctcc acagacgatt
    69421 tcttccatag gaatctctgt atactcgcca tttcgtttga cagctgccgt tactttcaca
    69481 agtgatttca gtttttcagc tgcttgatta gaacgcacag actggatcaa cgtcatcgtc
    69541 ccactgacga taaccatagt gaagataatg gctacaccaa agagatcttt atctcctgga
    69601 gcggctaata cgtattccgt aatgaatgaa ataattccta atgcaatcaa cactaatgta
    69661 aagggtgtga tgtatgcttt caatatttct ataatgaatg gtgttttttt gccatatgaa
    69721 atcgcatttt caccataagt ttctcttgaa cgctcgattt gttcttctga caatccattt
    69781 ggtgatgcat ggaacaattc aaataattct tgcttcgttt ttccagcaaa agctgcatag
    69841 attttttgtg tatctttctt tttttccatc tcgatctctc ctttgtgtcc aaaagacagc
    69901 tgttctcgct gtttttggtc ttttgctatt catcggatcg atagagaaaa tgctgaaagg
    69961 ggctgagaac agatagataa tagccctggc ctttcctcta aatccttgtt tttcgaatga
    70021 ctgtcatcca tttgttctca tctcctttac taagtaattt taattcatga cttccaatca
    70081 tttttcgaat agttattttc ccaactcgct cacctccctt tttgtttttt cacctatggg
    70141 atttgcggca acaaaaaaac ctctcgccaa atactcagcg aaaggtttga aaaagcaaat
    70201 caaaaaaagc ttctcagatc tcatcgttga gttttgacac tgtacaacgt aaaaagcaga
    70261 tatctgcttt tagctacctt atgaaaagcc ttatctcgac aattcctgtt ctacccattg
    70321 gcgtctctcg acgtttttgg gcagtagcct atgtttgtat aggagcctca cctaacaaat
    70381 cctattcggt tttccctcgt taatataaca actaaaaaag aggatgtcaa atcaattttc
    70441 catgtttttc atactttttt aaaatacacg cgttatattt cctgtctcac gcagttttat
    70501 ttgtctcatt ttccacctcc cgctataata gaattatagt aggaaacgag gtgctgttat
    70561 ggaacgaaca cttgttatta tcaagccaga cggcgtaaga cgccatttgg tcggaagcat
    70621 catccaacgt tttgaagcaa agggactggc cattgctgaa atgaaatttg caacgatgac
    70681 acctgaacta gcaaaagaac attatcagca cttgactgaa cgtagttttt ttgatgagct
    70741 tatcgattac atgacttctg gtccggtcgt ttatcttgtg ctggtcggcg aggaagtgat
    70801 cgatatcgtc cgtaagatgg tcggagcaac aaaaggggcg gatgccgttc caggtacgat
    70861 ccgaggagat tatgcactgc cggggactga aaacatcatc catgcttctg attcccgtga
    70921 tgctgcaaca aaagagatcg cccgcttttt cccgccattc gatacaaaca aaccgtctga
    70981 aaaagcggcg aagtgataca aatcctaaac tgttggtcta actgctgggt ttagcaatgg
    71041 ccagcagttt tttctctaaa gaattccttt gattcttccc taatgtatat tcgatcactg
    71101 cgaaaaactc ttggtgattt tccgattttt cttcccctaa agcagcagaa atcagtcgtt
    71161 ggtaataatc cgccatcaat gtttcataaa tcactgtact tctttcttta tgcgctaaac
    71221 tccgtttcat atcttcattc acgctacgtg ccttttttaa gcgaccattt tctatataaa
    71281 acaaagtcaa gttcgtcaaa aaagtaaaga gatactgctc gtgattattc agttgcgcga
    71341 tccgtcgcat tctttttttg attttcaaat aattattctc aataaaacga tcactgaata
    71401 tccaaggaaa atctgctaga atagatactt caaattgccc atactctggt acttgcatca
    71461 aatattcttc aatgatacga cattcataac gcaaaaattc aaattccgtc tcagatactt
    71521 ctgttttttt ggacatgtgc agattcaaaa ccaaatagta cagatcttct gttttcttat
    71581 agtgcctgcg gttattagca atttctttgt aaggatcaaa gctgtcttct tgaatccgat
    71641 ctagcattcg tctttttttc tttaattttt ttggctcatc aagctgattt cgtatccatt
    71701 catattcggc aagtgtcatg ttcattcgct ctaaaaatga tttcaatgtt ccaaacgata
    71761 cttttttcac tgaatttgtc tcgatcccga ctagcgaagt tttagaacag attccttccg
    71821 ctaattgggt ctgtgtcagc tttttgttga ctcgaagctt cttaatcaat tctccatcat
    71881 acataatagt tctccttttt taattgaaat taacccttgg cttttccaga atgcttgcca
    71941 ataagaggaa tgattatttc aatttaaatt ttccgcattc aataaataga tacgttaaaa
    72001 ataaaaaata cacgaaaaaa ataaaaaaat gtttttctca taaaaaatac caaccttcaa
    72061 gcatgagact gctgtctaat ccctgaaggt tggtttgatt gtttattgat cattttttta
    72121 ctgctccgca ttggttcctg ttactggata taggatagtc gttgttttat tgccgttttt
    72181 tgaaaagaca ctggtcgaat gttcaccttt ttgcttttcg attgcttcat tacgttccgc
    72241 ttcgttttta tagtcatatt ttttcggatc aatcgtctca aatccgtttg gcacataaaa
    72301 ccgcaagaga ttttcctgat tcagcttatc tgaaagactt aacgcagtct tgactttttc
    72361 ctgatctttg gagatttcct cgtcgattcc tgctgctttc gtatcgatga tttctcctgt
    72421 ctgattattg taagcttttc ctcctaggac ggtgtatttg ggcgtcacga agttcccatt
    72481 tcgaaaagca actacttgat cgtgctgaga agataataag tctgtaccaa aatgaagata
    72541 atctttatca tcgattccca atagatgtag taatgtcggc aaaacatcga tttctccacc
    72601 atattcatga ttgactgtcc ctttagtgta accaggcata tggatcatca atggcactcg
    72661 ttgcatctgt gcgttgtcaa attcatccca tgtatctgga tctttaccaa gagcacttgc
    72721 taaatcttta ttatctgtat tcgagatccc aaaatgatcc ccgtaaatca caaagattga
    72781 attttggtaa ataccagatt ttttcaaata cgtaaaaaat tgttccaatg attgatccag
    72841 ataatgggcc gttcgaacat aattatctac tgtgctattg ccagtattca aagatggaaa
    72901 gtcgaaattc ttgtcatccg tataataagg cgtgtggttg gttacggaaa gaaatttcgt
    72961 gtaaaacggc tgttgtagat gttcaagata ttgggcagat tctctgaata aatctttatc
    73021 taatatccca taacctaacg tttcatcgga ttcatcaaaa taagatcgat caaagaaatt
    73081 gtcataccct aaatttttat atacatgatc tctattccag aaactagcta cattcccatg
    73141 gaaaacagca cttgtatagc cttctgtttg accaagggtc gctggtgctg cttgaaagac
    73201 attatctgac ccaagttctg tgaataatga gccttgaggt aaaccaaatg tgccagtttc
    73261 caacatgttt tcagcatcac ttgtctttcc ctgtcctact tcatgaaaga aattgtcaaa
    73321 actgatcgtt gcttgattct ggaaaatact atttaaaaac ggcgtgactt cttgtccgtc
    73381 taccttcata ttgatcaaaa actgttgaaa actttctaaa tgaaggacaa tcacattttt
    73441 tcctttagca atcccaaatg tttcaggatt tggctctgca taatgtttct ttgtatagtc
    73501 taaaacttca tcaattccat tactgcttgc atgcgcgcga acactgctag tcattcctgt
    73561 tttgattccg tcataaatag tgtacgcatc gattcctaga tatttgacaa tataggaacg
    73621 gtcaaatgtc cgctgtagca attggggacg gttggcttcg ctcaacgcta aatttcctga
    73681 aaaaatcaat cctgaaagac aggtaacagc gatagccatc ggtttgctga cagggttgct
    73741 tttgataggt attttcttga ccttcaacca aaccagtagc ccaatgaaca cagcgatatc
    73801 caaccaatag atgacatcat ggggtttcat caaagaaaag gagcttcctg acaacccttg
    73861 tgacactttc gaaaagccta atacagattt gactgtaatg aaatctgtga attcccgata
    73921 aaaaataata ttcaagtaca acaaaagcgt atttaaaata tcaatgatca aaagaatggc
    73981 taacgctggc tttggctttt taatatacaa agaaaggcca aaaaacaata aggtagtcgc
    74041 aatcgggttg atccacaaga taaagtactg gatcgtacct tccacaccta atgaaaaatc
    74101 tgcatagtag gcaatgatcg tcttcagcca gaaaaagaaa acagctgtca aaacgattgc
    74161 taaacgattt tggcacaatt ttttaagttg tgtcacgtat atcacttctc tctattcaca
    74221 ttttttctta ttttgctcct gaaaaatgaa aatttcctaa aaaagttgtt atcttaagat
    74281 ttttttattc tttctaaaga ttattccatt catttttcac agcataaaat cgtttcggtg
    74341 taagcggtta aaatagtaag gagataaaaa tcttgtggtg accgatttac tctatagtat
    74401 tcaaaagtag tttctcggta ttcgtacaaa aaaaacatac taagattaga ggggaacatc
    74461 attgacgaat gatgttctcc tctattttct atttttagat tatagtgaag agtgaaagaa
    74521 agttcgaaca aagccttgag gactacgagt ccctatcaaa aaccgaactt ctttactgtc
    74581 attttagaat caggtttacg tatgttgggg ccatgagccc gtgtatagga aattggaatc
    74641 gaaatgaagc agtaaagttc tttcaacact taaaaaggag gaaaacaaat gccttacatt
    74701 cttgcattag atgtttcaat gggacacagc tacagtgtcc tatacaaaga cgacacctgc
    74761 ttatttgaag acgagatcga acacactcaa agaggatttc atgcattact cgaagagatc
    74821 cagcacttgc ctgaacgtcc attgattgtt tttgaagcaa cgggtattta ttccagacca
    74881 gtcgaaaagt tctttcaaga tcatcacttt tcttactgtt tgttaaaccc gttagaagcg
    74941 aaaaaacaga tggaagaaaa caccttacgc agttggaaaa cagataaatc ggatgcccat
    75001 cggctcgcac agactcatct taaaaatcaa cgtcaaccaa aagaagtaca aagcaatttt
    75061 tacttagaga tgcgcgattt agcccgtttt tatcaagaaa ttgagaagaa aatcactcga
    75121 ctgcgcatgg atttacacaa ctgccttcag ttgacttttc cagagcttga acagttcttt
    75181 tcaaacaggc tgacccctta cgcattgaca ttgatccgtc tttttcccca tccagatttt
    75241 gtattggcat ctactcggac aaaaataaaa aataaactga tcaacgaaac acgggaaaaa
    75301 atctccgcga atcgtgccga gcaaaaggca gatcaaatca tccactatgc acagtgtgcc
    75361 tatccagctg ttgaaaaaga cagtattcac tgtcaaaaaa cgatctatta cgccgaactt
    75421 ctccaagatt tactcgaaca aaaaaaagca ctggcgacac aaatgatcaa aaaagccgaa
    75481 gcctctcctt gctttttgtt gtaccaaacg ttccctggga ttggcgcact cacagccgct
    75541 ttattgctcg gtgaattagg agatatcaca cgatttaaaa cccataaaca attgaatgcc
    75601 tttgtcggaa tcgacatccg acggtatcat tcaggtaagt atactggcca agaccgcatc
    75661 aataagcgtg gtaatcccaa agcacggaaa attattttct tcaccattcg aaatatgatt
    75721 cgccagcaac gcgcagctcc taatcatatt gtcgattatt actacaaatt aaaaaagcaa
    75781 cctatcccta agaaagataa ggttgccaca gttgcttgta tgaacaagct tctgaaatgt
    75841 atgcacgcta tggttagggc acatacagag tacgactatg cgtacgcggt ctcagtggac
    75901 cattaactaa accacttaca gtataccact tctttgccca gatcgaaaat tttttacgaa
    75961 cggggcttta tttagtgtgc cttgattttg tcgctttcgt ttacgagcta tttttcttgc
    76021 accttttact tgactaatcg taggaaagag gctgtgacaa aattcttgtc gcagctccct
    76081 atttcttgat gcaggacagc tttttcacaa cctctccact aaacggtgtt caatcagctg
    76141 accttcggta ttagctcaaa aaacggcaaa atatgaggag ctattttccc gtttttttct
    76201 ctaatactca ggtcaaaccg ctgatttcac aacctctgat tcacggtgtt ccagaagtag
    76261 cttcttcgga aataagccga aattttacaa aaacttgaga agcacttttc gtaaatttct
    76321 tcttatttct tgaagctgac cacttctgtc acaacttctg tttttcattg tccataggtt
    76381 tgatattgtc cttctgatga ctcattcgta atgattgagg cttgattttc ttcatttccc
    76441 gttatcgttt gtccactgcc agaatctgaa gggcttagtt ctgtcgactc gtttttttga
    76501 gaagaagcag ttgttttctt gacttgttcg ttggtctttt tccattccgc tagtcgatcg
    76561 gccaccactt ttttgtccac tttttcagaa taagctgtaa ccacttttcc atttttcaaa
    76621 cgtgctacct tgtcgccatc atgagtcaaa agcaaaacga ccaaatgttt gtctttgaat
    76681 tgatattgtc tgagagaaat cgcactaagt acgtcatcga tattgataaa ttgattttct
    76741 tcttttcctt ttggcaaata gatgtccaat tcaccttttt cgtaattggc agttaattta
    76801 tattcctccc accaataagt tgagaattct tttttgaaat tatctactga ttctttgctt
    76861 gctacgattt tttctgtttc tttctgagca agatctgctg tcatttttcc tgaaaatgct
    76921 gcggataaaa taagcagtaa gaaaaaaccg aataaccaaa agagaagaaa cggtcttttt
    76981 ttcctcatgc cttcctccac tcctatttaa ttttgactat tctattatat acaaaaaatg
    77041 aaatagaaag acaaaaaagt tgaaaaagat cgtaaataat tgaacttctt tttcctgaag
    77101 cggtaagaac gggaattttc atacattctc tcttggctat tctttaagct tcaaatccat
    77161 ttctgtctga tacatctttg aaccaatgac ccgatttctt gatcgttctt tttccatctt
    77221 gtgctaaatc tactgaaata aaaccgtaac gattcttata ggcattggtc cacgaccagt
    77281 tatccatgca tgtccacata tgataaccta aacaattggc accttcttga atggcttgat
    77341 ggacatattt cagatgagat tgaacaaatt cgatccgata atcatcgtgg atcataccat
    77401 cttccttgat aaatcgtgct tcattttcta cacccatgcc gttttcagaa ataaaacagt
    77461 cgatattccc ataatgatct cgtacattga tcaaaatatc atagattcct ttttcataga
    77521 tctcccatcc gcgataagga ttcattttac gaccaggcat ttcataattg tcgaagtaat
    77581 cctcaggcat aggaccgttt ttagtatcga ttggtgtttc ttttgctttt attcggcgtg
    77641 gttggtaata attaattccc aaaagatcta ctgtgttttc tttaatgatc gtcaaatcat
    77701 ctggatgaat ctccggcatt agatcgagtt cttttattct ctcaatcaat tcactgggaa
    77761 actcgccttt tacagctgga tcaaggaatg aacgattgaa gaacgcatct gctattcgtg
    77821 ctgctttaac atcttcggga tttgattcgt ctcttggata actcggtgtc aaatttaaga
    77881 tgattccgat cacaccgctt tgatccattt catggtaagc tttgatggct aatgctgaag
    77941 ccaacgcttc atgataacca acttggattg cctttttcat atctgattct tccggataat
    78001 gccatcgata caaatagcct gcctcgactg gaacgattgg ttcattatgg gtaaaccatt
    78061 tttttacttt cgagccaaac aattgaaaac aactttttgc gtatttttca taggcttcaa
    78121 ccgtttctcg gttcaaccat ccgccttttt cttgcagata catcggcata tcgaaatgat
    78181 acagattaac aaagggttcg ataccgtttt caatcaactc atcaaaatag tgatgataga
    78241 aacgaacggc ttcttcgttg attgttccag attcatcagg tatcaaacgg ctccattgga
    78301 tagaggttcg aaatgaatta tgcccagtct gtttcatcaa ctgtacatcc tcttgatact
    78361 tcgtataaac ttgcgaggtt ttttcaggtc ctacttgatc aaagaacttt tgcggttcgt
    78421 ttttgtacca ataatcaaaa atattctctc cttttccatc gcctgaaatt cttccttctg
    78481 tttgtggacc acttgctgca gagccccacc aaaaattttt tggaaattga tatcttttca
    78541 tcaaagcacc tctttttctt ttttagttga ttccatgtat gatattttcc atcacaatca
    78601 ctttttcatt ttcttcctct tcttttttga ttcgtttcaa cagctgttct gctgctcgtt
    78661 ccccgatttt atctgttggt ggcgtgatcg tgatttttgg aaggatactc agatcgtttt
    78721 tatctaaata atcatagtga ctgaacgcaa tatccttccc gattctgaca ccttcttgat
    78781 tgaaacattc gatggcacca atcgacatgt tgtaattgct gacaaaaata gcagttgccc
    78841 ctttttctaa taatgctttt gccccgtaat agccgctttt tctagaatag tctcctgtaa
    78901 agatctctaa atggatagac ggatcctttt gtaccgcttc tttggctcca gctaaacgtt
    78961 ctcttgctac gtaatctgtt tgagcggcag caataaatcc tattgtttta tgtccttgtc
    79021 cgccatgatg agcaatcact tttgctacac tttctcgatc attcactact attgtatcaa
    79081 tacctgctgg cccacccgga caattcaatg cgacaactgg gatactcatt tttgtcagca
    79141 tttcaaatcc agaccactct tcttctgata agaagacgat caatccatcg atcgcatgct
    79201 tcatcaggta ttcgattttt tgttcgattt tttctggctg atcggcaaac ccgcttaata
    79261 ataagctata cccattttct tcagctactc tttcgatccc tgaaacaacc tccgaaccaa
    79321 atcggttaga tatcccgttt atcaacagtc caatagagaa acttcgatta ttcttcaatc
    79381 ctttagcaat gatgttttct ttatagtcca acgctgaaat cgcttctgat attttttcca
    79441 tattcttttc cttcagctgc tgaccgttta aatagcggga aactgttccc actgaaacac
    79501 cagccatctt agccacgtca cggatcgatg ccatacattt tcactcctgc cagttacatt
    79561 tgatttcttt ttcttgttgt tcgaccatga tgaccgcttt ctttgcataa tgccgcttgt
    79621 catcaatatc catataacta aagtcttcag aagtgagttc aaaaacaagc agtctttcct
    79681 cttgagaccg caattcatct ttacgaaaag ctttcaataa tttcgttctt tggatgacaa
    79741 cgccgtcaat taatcggaca tagacaagag tacttgtttt acctgaaaca cttcctgtat
    79801 ttttaacttt aattgatatt attactttgt caatatccgt tttgacttcc atctgactgt
    79861 attcaaatgt tgtatagctt agaccatgtc caaaaggata aaatggactt ccgcttaaat
    79921 cataataatt ctcttgttta gaagcagcac gctgatagta ataaacaggt agttgccgac
    79981 tatttctagg ataagacaaa ctcaatcgtc cgcttgggtt atttcttcca gaaatcatct
    80041 gcgcaatggc ttttccaccc tcctgtccag gaaaccatgc tgttgcaatg gcattcgtaa
    80101 atgactcgat tttcatcaaa tcgtagggtc ttccttgcac aagtatcgtg atgattggct
    80161 tgcctagttg atacaattgt tcaatcagct gttcttggta tccacctaaa gaaagagaag
    80221 caacatctac attttctcca gaatccatgt tgatcccttt cgatgaaact gccccgttac
    80281 gaagaaattc catatcaaag ttccgcgcac ttgatccacc tagaactgca atgatcacat
    80341 ctgagttttg agcaagggtc accgcttcta ataatttttc ttcctgatcc tcctgatttc
    80401 ttacttcaca tccttgtgca taagaaacct ttgattgggg aaactctgtt tttatctctt
    80461 gtactatctt ttttttcaaa cggtcttctg tttgtggtgc agagtagtct cccaacaagt
    80521 ggtaaacatc gtgagcattt ggacctataa cagcaatgtt ttttacttgt tgatccaacg
    80581 gcaatatacc gtcatttttt agtaaagtga tactttcttt tgctgtctct aaatttaagt
    80641 gctctgattc ctccatgaga tgatcccaat actcctttgg atcgtttgca aatggctgtt
    80701 caaataaacc taataaaaat ttgacagata aaactcggcg aactgcttga tctagtagct
    80761 tttcatctac gacttgatta tcaatggctt ctgcaatctt ggtataggtc tcatcccaca
    80821 aactgagatc gattcctgcc gctaatgcat atgctgcagc agtcttttta tctgtaaaaa
    80881 catcggataa acgatccaaa gccacaccgt ctgccataac gattccttga taaccgatct
    80941 cttttcttaa tgtttgctca aaaagcgctc gattgatatg acaaggtatc ccgtcgatgt
    81001 cattataagc agccatgaca cctactgcat ttcttgtact cttcaataat ggtccgtaaa
    81061 tatcggagaa ctctctgcgt ccaatcgtta ctgtgcctga attatgaccg cctaaagctt
    81121 ctccttgtgc gatacagtgc tttaacacaa caccgatctg atccttcttc ttattgattt
    81181 cctctactgt ctgatcaaga aaagaaactt tttctgaaat aatctctcct tggaaccctc
    81241 gaacgaccgc ttcagaaaaa cgagctgaga gaatcggatc ttccccaaag cactcttctg
    81301 tccttcccca acgaggatct tttgccagat ccaaagtcga caccagcgct aaatgaacac
    81361 ctttagcagc cagttctttt gccatcaatc gactcgattg ttctaataat gctacattga
    81421 aagtatttcc acggccgata ttcgttggat aagaaatccc atccaagcct tgatgaccat
    81481 gtggacattc ttctacaagc aaaactggaa ttttccatcg cgaatgctgt agtacatatt
    81541 cttggactag gttagccacc ttccagcttt cttttgcagg aatcccattc ttataatctg
    81601 ttttagacca cggatcagag cgaaacagac cgtataaggc acccagaccg cctccccatt
    81661 taacatgttc ttttaacttt tctgttaatt cgatcttgtc tccgtttttt tcataacatt
    81721 cccaaccata caaatgctgg tttacctgtc ctactttttc agcaatattc atcctcgaaa
    81781 gtaaatcttc tactctttgg cggatggtta actttgggtt ttgatacggg taatcgtaca
    81841 ccttaatatc ctccttctgc caattttgcc ttattagcgg ctaatacaaa tggcaggaat
    81901 aaaaatacat ctagaatgat aagtattact gttaagactg ctgctcgtat atcgcctcct
    81961 gtagcaataa aagattgtat aaccggtgga gtgatccaag gtgcagcagc aactgtttta
    82021 ctgatgattc caagacttgt ggctgcgtag gcaataacca agttaataga tggtataata
    82081 gcgcatggaa tcatatatat tggattcatg actactggta atccaaacat aattggttcc
    82141 gtaatattaa ataaacaagt agtcagacca aatttagcga ttgatcgctg ttcttgacgt
    82201 ttagaagccc acaagatagc aataactaac ggtaaaatac acccgccacc tccgatcaat
    82261 ccaaatgcat tggtaaaggg ctccgtaata atattaggaa tttcttttcc tactgaaaaa
    82321 gcatccatgt tttcctgaat agactgtaac aaaggtgctt gccgtatagg agccaaaata
    82381 ctcgaaccat gcataccaaa cacccataag aaatcagaga aaaactgtaa aaataagatg
    82441 cctgggacgg ataaaacaaa agctttcaat ggtgtctgaa tcgctaattc aattaattgc
    82501 ggaacattca aaccagtcgt atggtttaaa gtaaaaacga caactgaaaa aaataaaatg
    82561 acaactattt ctggtactaa agaattaaat gacgcagcta ctgccggtgg aactccttct
    82621 ggcatcctga ttttaaaact cttcattttc gctaatttga taaataattc tgtactgaca
    82681 agggcagcaa tcatcgccgt tgctaagcca gacgaagaag tcagactttg taagaaaacc
    82741 cctgtagctt ctgctgtatt tccgtccatc aaagtgactg tacttgataa agacatcaaa
    82801 ataaacatta cggctgtact tagaattcct gcatgaacag gactaaatga tggatcatca
    82861 atcacgcctg tttggatata gtgggttgcc aaattccagc cgatattgta acacacgata
    82921 atagctaaaa tactcatcgt accattattc acgattgaag caagttcagc caatggactt
    82981 agatcaagta ttctttggac tgttgcattt gaaaaaatca gagcattcag caaaaccatg
    83041 acagaagcag ccattactaa cggcatagta acgataaaac tgtctcgaat ggccagcaag
    83101 tgtcgctggc tactcatctt agatacgatt ggtagcattt tttcagatag tctgtctacg
    83161 actttcatta tttcatctcc tagattctaa aattgaaccg gttcattttt aatatagcac
    83221 tttttttaaa gattgcaaca cattttttta aaacgctttc taaaggtggt ggatttttta
    83281 tgacttttga aaaattattc tatttaatgg tattttgtga attttttctc ttccatccgt
    83341 ttgaagtttt actttccaat ggtataattt ctttatccta tcaaatgggg gaagtatttt
    83401 gaagaaatta atcgtactat ttattttgtc tgcgggactt ttgacattga ctggctgtga
    83461 tttgtttggc ggctctgacc aatcctcgga cgaaacaacc gattcttctg tcttaaaagc
    83521 ggaaaaagca gatatcacca acagtgtata tacgctaaaa gtacgtaaag atatggattt
    83581 atccgcggga cagttgacat ttacagataa aaaaatggaa tggacacgca cgtatcagac
    83641 acaaggagct gattcttctg aatcatctga agaaaaaaca gtgctgacag atatcaagat
    83701 tactaccaaa gatgacgaat atattatttc aggaaaagaa aataaaaaag aagcaacagt
    83761 cacatttacc aaaatcggta attaccgttt gaaggataag gatggcaaca tctacagtct
    83821 atagtgccat ctgttggatc ttcttttgtt tctccccttc ttttctgcta tagtaaagaa
    83881 gcaagatgac tgtaaaggag acgaaatgga tgatcgatag tcctgattat tgtacatgta
    83941 ataacaacaa aaatatccat acagaattta atgatcaagg aagtttgagt atatgcgaca
    84001 attgccacaa actagtcaaa gattctttta aatcgtttga atcttatcct gtcaaaaatt
    84061 atgtaaaaag caaaagaaga taagcaaaat caagcaaaac tcactatggc tgatttttat
    84121 gaacttcaaa ctcagcttct tcctttgatc aagcttcaaa aactggaatc agtaaaacaa
    84181 acagtggatc atttcagttc acaaatcaaa gagtaacgtt ttatttattt cacatctttg
    84241 aatataaaat aaccaaacga tagaaagact tattctacat cacgtagtaa tttttctttc
    84301 ccgtcgtttg gttttttact tttagcctaa ttcttgacct ttcgcatgct gattatctgt
    84361 aaaatatttt ccagcaggct ttccttccaa ttcagctaat ttttcttgga tctgacgaat
    84421 cacctttttt gcatcttctg gattttctac aaaatcgaat gtatccccat ccacttgtat
    84481 tttaggacat acatcaaaat cctcatacca ttgattatag cgggtgttca gtgtttcgta
    84541 ataggtgtat aacgtttcat cgctttctag ctgttcatag tcacgcccgc gttttttgat
    84601 acgttctagc atcgtgtcca aagaaacttt gatatggacc atcaaatcag gacgtttttt
    84661 tggagcaaca tcatctaact cgtttagcat cgtatctaat aagctatcgt actgctgtac
    84721 ttcgatatcc gttacccgac ctaaatcagc atttagatgg aacaacagac tatcttcgta
    84781 gatggagcgg tctagcacat tgtcatcgtt cactaaagca tttttcattg ctaaaaatcg
    84841 cttattcaaa aagaagattt gcaataaaaa tgcgtactgc tcaggatttg aataaaaaag
    84901 cggcaatact tcgttatctt cgacattttc ataaaatggt ttagaatcaa tctcttttgc
    84961 aagcatatcc gtcaaactgc tcttacctgc accaatcgtt cctgaaatca aaatcactga
    85021 catacaaccc ttcctcttct ataagtactc gcctacgtaa gtttcaacag gcaatttttc
    85081 aaaatcatat tcacgtacag cttggtctga ttttaaatac gtgtgaagac tttgtgtaat
    85141 catcaagttc gtaggtaccg tctcttcttg tacgatgatc atcggttttt tcaacatagt
    85201 tgccacacct aattcgtaag ccgttcctgg atcgattgtt tgatgctcaa agtcaaggat
    85261 agccaaaaca aattctgcat ttgtcaactc ttccatatct ttttcgtata cttcctgcgc
    85321 ccatccagcg ctgaatagtt cataattgct ttcttggtga tgacgtggag agtagaaact
    85381 tgtgattgtt ttgttttcct ccaacgcttt ttcgatacga cttactcgat cgatttgctc
    85441 ctctgaaaaa aatggtcctg ctaaatatat ttgactcatt attttgcctc cttcaataat
    85501 aactgatttt taatagatac tgctcgtaat tcattgacca gttccaatgg attgttggaa
    85561 aagatcactt gatccaacca ttttttatcc ataaaatcct cttttgcaaa agtttctaat
    85621 aattgttgca agccgctgta ataaccgcca atattcaata ttccgattgg cttatcaggt
    85681 gtcaggccga tcgctatcca agaaagaagt tgcgaaaatt cctccaatgt acctagacct
    85741 ccagggaaaa cgaggacagc atctcctttt tcaaataata atacctttct ttcatcaatt
    85801 gtctctgtag gaataaatgt agtaacatct ttcccaggca gctcagtttc aaaaaggcca
    85861 tttggataga tacctgtgac ttttccgtta ttttccagta ctgttttact aatcactccc
    85921 ataatcccgg agtatgaacc accgtaaacc agttcgattt cttcttgtgc catatatttt
    85981 cctaacgttt gcgcaataaa tttgtaactt tctttattgc caaaacggga accgcaaaaa
    86041 acagtaagtt tcataaaaaa acactcccta actcaaaagt ctatcttcat tctacacgtg
    86101 tttttttaaa ataaaagact agattttgta gttttttagt ggtatataga tcaaacacca
    86161 ctatatatag tatttgcaaa aaaataattt ttcagctatt ttacagtaac caaaaaaata
    86221 aataactagt aaatataaaa ttgaaacgac ttacttatag aagaaattgg gatttcgtcc
    86281 tgcatgtcaa taacacgcat tatttaaata gtcacacact tgtttctcct attaatgaaa
    86341 aatccatttt attctcgtgt tatgtttcac caacgcctga tgtttctcta aataaaaaag
    86401 ccgacgaacc aaataatcga aatttgatca ttttggttca tcagcttgtt cccaaacctt
    86461 tgtattaacg ataaatagct ggattcgtaa aactatcact tggatcatca ctgctggaag
    86521 aaaattcggt gataaccgcg cctgttgcac ctgcctggaa ccagtgttta atattttgtt
    86581 cgatcgtgta ctgatctcca gcgtgaagta tgatttcttt ttttgccgta tagtaacgtt
    86641 cttgcccctt tggaataata caggaaagtt tttttgtttc ttttccttcg acataaagat
    86701 atactaagcc ttttcgacaa cgaaaggttt ccttttttcc ttcattctca tctcgaggtg
    86761 ggtgccgatg ctctggacaa gtttgataag gcaataatac cagttctttc ccacagtatc
    86821 gctcattatt ttcataaaca aataaattca atccttcagt ctcgattgct cctaatccaa
    86881 aatctgtata ttcgattctt tctaattctg tttctttcaa tactactcct gaatctagga
    86941 acatttgttg tactcttttc ttgtaatcca ttctgttcct cctaactgat tgtcaagtca
    87001 tcccaagata tctcttcttc ctctttttct tcttggatga cttctgcatt tgggtcaact
    87061 ggttttttca ataataaaat agttattccc gtagcaaaag aaccagctaa caatgcacca
    87121 atgaatgccc atggtctggt catcgtagcg actgcaaaca ttcccgatgc cggaatacgg
    87181 ctatctgcgc cccaaaacat gctcaatcca ccgccgactg ccccaccgac tcccgttgct
    87241 atgacattgc gtgccaagtc gttcaatacg atagggatac atccctctgt gatctgacag
    87301 atccccatag gaaaagcggt cttcaatgta tcgatttctt gacgattgaa tatattttta
    87361 cgaatgattt tccctaagaa ataagcgatc gtcaagccga atggggttac catcgaagct
    87421 aaaatcaata cagtgattgg ttcatagatt ccttctgaaa atcgtgccac acccccttat
    87481 ccagaataaa tggtaatcca gaaacagccg ggtatctgcg gtaataagcc taaccaaacg
    87541 aaaaatatga gaagctaata tgagaagcta tttttgtttg gctgttctta ttacttgatg
    87601 cagggcagct ttttcacaac ctcttttttt atttatgttt cataatcaat atggtaagga
    87661 tgcagctccg tatggtagac cgcctccgaa tattcaatca tttccccaat ttgcgtagac
    87721 gatttccgta tccgtttgat gccgatctgt gcgtctgttt tcagaatttc ttgttcttct
    87781 tctgttaaaa atactgccga gaaatcatca gaaaatgagt caatagtata tccttttttc
    87841 gtcagcaaac gatacaaaga ttctttgcca aattcttctc tgctgaattg catcatttct
    87901 tgtggaagat aatgaacaaa ataaatataa ggctgattgt tcaaataata taagcgctta
    87961 aaacaaacag cttgctcacc gaaaaaggaa aacaaaggat cttccttctt tatatggacc
    88021 aattgcaaat ccagcgtttc tttccggact tcatatcggg agttctccaa gatttgcgta
    88081 aagcttgccg ctttggataa tcgattgtaa ggacgattgc ttagaaccgt cgtcccacga
    88141 ccacttttct ttgcgacata ttcatctgat gccagcagtt cgattgcctt tcggacagtg
    88201 attttgctga cttgaaacag ttcttctaat tcactttctg tcggtaacat cgaaccgact
    88261 ggatattttc ctgagaaaat atcttcttta attttatctg cgacttccaa gtatagtaca
    88321 cgtgtccttt tcataacgtc accctttgct ttactattac taaaagaata gcacataaaa
    88381 aataaaaaaa gaacacaaat cacatgtgag aagtgtgttc tttttcattc agctgcttta
    88441 attacaagtt tacgccattt gaggcaatta cttctttata ccaatcaaaa gattttttct
    88501 ttgatcgatt cagtgtccca tttccttcat cgtctagatc cacatagata aagccgtaac
    88561 gtttactcat ttctcctgtt gatgcactga caagatccat acatccccaa ggcgtatagc
    88621 ccatcaaatc tacaccgtct gctactgcat tagccatcgc ttcgatatga cgacgtaaat
    88681 aatcgatccg ataatcatca ataatcgtgc catcctcttc catatgatca atggctccaa
    88741 gaccgttttc aacaatgaat aatggtttct ggtaacgatt gtataattca ttcaatgcga
    88801 ttctcagccc ttctggatcg atctgccagc cccattcact tgcctcaaga aacggatttt
    88861 ttactcctcc cagcaagttc ccttctgaag ttgctgcttg tggatcagtc tcattgattg
    88921 ccgtagacat ataataacta aatccgatgt agtccactgg atattctttt agcaactgga
    88981 agtctttttc cgtttgctct aatttttccg gatcgactcc atatttttta tgggtacgcg
    89041 ctgtgtatgc agggtattct ccacgtactt ggacatccgt gcagaaaaaa ttgaattctt
    89101 ggttttggat cattgttgct gcctgattga ctggattggc atcgatgctg taagttgttg
    89161 catagataat catgcagccg atttggatat ccgaacgcaa ttcgtggccg atttttacgg
    89221 ctttgctact tgcaacgaat tgattatgcc atgcttggaa aatattttgg tactctcctg
    89281 ctccattgct ttttactaat ccttgactta aagctggaaa gtgaaaggcc gaattgattt
    89341 cattgaaagt catccaatat ttgactttac tgctgtatct ctctaatact gtctgagcaa
    89401 atcgttcata gaagtcgatc agttttcgat ttttccagcc accgtattct tttgccaaat
    89461 gaagaggcat ttcgtaatga gaaatcgtga tcacaggttc aatatcatat tttaagcact
    89521 catcaatcag ctgatcataa aattctaatc ccgcttcgtt aggagtacct tcgtctccat
    89581 ttggaaaaat tcgtgtccag gcaatcgaaa aacgataaca tttgaatccc atttccgcaa
    89641 acaaggcaag atcttctttg aaacgatcgt aatgatcaat tcctcgatga ttcgggtaaa
    89701 tatatttttc ttgatcaatc gtccagtcaa attcttcact gccgataatc gcaaagcgct
    89761 gcttacctcc aggcatagca tctgcaacgg atagcccttt tccgtctcga tcataagccc
    89821 cttctaattg attggcagca gttgctccac cccataaaaa tttttctgaa aaacgtgatt
    89881 gcatcctgat ttcctcctta ttttacaatt gccagaacat cttcgtttgc aataatctct
    89941 ttttggtcta attcaagtat atcggcaaat gcatcagtat tcgtaatgac aactggagtg
    90001 attacgctat agccagctgc tctaattgct tcgatgtcaa aacgaatcaa taaatctcct
    90061 gctttgacga gatccccttg tttgactaag atctcaaagc cattcccatt taattctact
    90121 gtatccatcc cgatatgaat caaaatctcc gctccgtcag tcgttgtgat ccctacagca
    90181 tgtccagttg gaaaaatagt cgtgatctct ccgtctgcag gtgcaactag ttctcctact
    90241 tctggatcaa tagcgatacc ttttcccatc acgccagaag aaaaaacttg gtctggtact
    90301 tcactcaatg gcagtacttt acccgttaaa ggacttttta aggtatgccg tgctgaagta
    90361 atcggttctc ctgcattcgc atgtttgttt tctaattgat tgtcttgtgt ttgttcgtca
    90421 aatcctaaaa tcaatgtacc tacgaatgca agaacaaaag caattcctgt agctattact
    90481 gctactgtca catttgactc tacaccatcc accgtattaa tgaaagtcgg aatcgtcaat
    90541 aagctgacca aactgctgga gaaagctttt actccggaaa atccgataat agctccacca
    90601 atacctccag aaatacaagc ggcaatgaat ggtttcttca aaggtaatgt cacaccatac
    90661 acagttggtt cagtgattcc aaataacgaa gtcactgtag aagaaatccc taatgctcga
    90721 agtttcgtat cttttgttcg caatgctaca gctaaagcag ccccaccttg tgccaagatg
    90781 gctggaagaa gcattggcat caatacatca aacccatatt gttcgatatt caaaaacatg
    90841 atcggtacga atccccaatg catgccgaac atcacgaata cttgccataa acttcccatg
    90901 attagacctg ctacgattgg actaaatcca taaatcgagt tgaagagacc gcctaaagca
    90961 ttaccggcaa ccgtcccgat tggtcctaaa gcaagaaatg ttaatggaac catcactact
    91021 aaaacgacaa gcggaactaa aatcatttgc agaaattgcg gaatcacttt ttttacgaat
    91081 ggctctaatt tactttgaac ccatacggct agaatgattg gtatgacaga agaagtataa
    91141 ccagatggtg aaagaatcac tgggatccca aagaaactga tagcttctcc cgcaccagca
    91201 actgctgtga tagctggata cacaagtgcc atagcaattg ctactgctaa aaactggttg
    91261 gctttgaact ttttagctgc tgtaaaagca agcatgacag gtaagaaggt aaagacacca
    91321 tctgctgcag caaacaatat ttgataagta ccgctatcag ctgtcagcca gcccatcacc
    91381 gttgccaatg ataagaatcc tttcaatacc ccggcggctg ccatcgcccc tagaaaaggt
    91441 gtaaatatac tagagataat atcgatcaga cgattcaaaa tatttttgga ctcttctttt
    91501 ccatcctccg aaactgcaag accttcctca tccacgatcg attgataaac atctgctaca
    91561 ttactgccaa tcactacttg atactgaccg ccactttgta cgacttggat cacgtccggg
    91621 tcttctttta acttttgcgt atctgctaaa gattcatctt ttaatctgaa tcgcaaccgc
    91681 gtagcacaat gtactaaact tttgacattc ttttgtcctc ctaccgcttc ccatacacga
    91741 cgaccaactg cttgattatc cattgttttt tccttctttc ttttttattt aaaaaataaa
    91801 aacccagatt gaaaaaaaca gtcacaaaca ttcgtgaacc tattttttca atccaggttt
    91861 tgcctgccat acagtaacaa tccttatgat tggatgcttt ttttctcact tactactctt
    91921 tgaatatgaa tcgttaaata aatctgctct gcgatcccca tttcctgttt ttgcgtttgt
    91981 cgaagatact cattgatccg ttcgacacaa tgaaacgctt ttggatactt tccttgaact
    92041 aatgcgtaga gaaattcatc ttgctcgtca gatccttccc ctttgagata acgctgggca
    92101 aaaaactgca gatgagtaat gatacgctga taattcaaag attcttcatc gaacacgatg
    92161 ccgaagaatt tactgatgat actcagtata tctcttacca ttgtggtagc ggtcatcgtc
    92221 acttgcatgt cttcgtttcc ttgttggcta ttcacaaaat gaaaggcaat aaaaccggct
    92281 tcatcctcag aaagttccac acccgtcttt tgtttcacga acaaaagagc ctctttcgct
    92341 gcttgatatt ctttcggata aaattttttt gtttcaaata ataatggatt aggcagttgg
    92401 atattttctt ttgctcgtgt gatcgcataa tgaagatgat cggtcaatgt cagataaata
    92461 ttaggcgaaa attcaacttt tagtttatct tcagccagtt cgactacttg tttgacccat
    92521 tcgatctcct ctgccggaat atcagccatc agctgctgga attggttttt agcaaaagaa
    92581 tctcttaaaa caaattcttt ttggaccgct tctggcgaaa tctcgtcccc aatctttttt
    92641 tgaaaagcta gtccttttcc catacaaacg acttcttccc cgaatccatt tttcgaaatg
    92701 acgacattgt tattcaaaat tttatcaatt ttcattttgc ttcgccctct caagaaaaat
    92761 aaaaaaacct agaattcgcc tactgtttct tagctgaatt ctggttttgc ctgccgtaca
    92821 gtaacaatcc atttcttatt caaaatcatc ataccatcga atttttattt atgcaagcct
    92881 tttcatataa aaaataaaaa aactggaaca caagtctatc tagaaaacaa ccaaatcaga
    92941 gatgcacctc tttgcgtttc tctttttttc agcaaattgg tttttcctta tcgattcata
    93001 tcctttggct gtttttaatc tgtaacgact tatgtcccag tatcctaaaa tgtttttgtc
    93061 tctagattga aagcagatct catatcatct gtcgcatctt ttatcgatgt aacactttcc
    93121 agttctcctt gtacaactag tcgcgtgacg gcgtccatgt cgccacaagt aattagtgtg
    93181 acaatttctt ttccctcgac ttcattcagt aattgggtat ctgtaggagc aactttttct
    93241 ttaaaaaatg ttttgtatgt atacacattt tctaaatctg tcaaatagat cttggcaccc
    93301 atctctaaat tttctagcgg tgtaaacagc aattcagggt tcgttgcacg atggcttgct
    93361 aaggcataat ttccttttcc catttcttga tctggagata atgttcctgc tccgtaaagt
    93421 agtgacgtat tatccaagcc tttgaaaacc ggtaaattga ttgaaactga agggactgcg
    93481 atactagcaa tcactggtag atctgttcct ctcatttgcg acctcatgac cccttctgtc
    93541 gtcattggtt ctaccgcatc aaagtcaaaa ctgacatctt tatcgttatt ctttttcaga
    93601 tcttcttttg ttacattcgc tatagcatat ttatctcctg tctctctgac aaaataatcc
    93661 ttgatctgtt cattgaaaat caaagctagt cctactaata acaagaggaa caagaggata
    93721 ttgactagcc atctttttgc ttttcctttt tttttcattt tctctccctc cagactcatt
    93781 ttactgtttt tcttttgctc tttccaacag ccgaatgaca catttctaca actctgtgta
    93841 tttttttcgt acacctgcgc ttttttctac aggatatttc aaattatttt tgatcaattt
    93901 ttcttcaatg atctcatcta gatccaggtg aaggttgtct gccatcatgt atgaatagat
    93961 caatacatct gccagttctt ctttgattcg ttctaattgt gtttctttta cttcttccgg
    94021 cgttttccat tgaaaaagtt ctaacaattc agatgcttcc aaagaaatag agatagccaa
    94081 atctttttcg ttatgaaatt gtcgccaatt acgttcatct ctaaactggt tgactttttc
    94141 catactattc atttgcttgc cttcttccaa tcacttctta cttgattaat cataccattt
    94201 ttttacataa aaaatagatg atgcttttaa aaaaactcct gttttctttt atttaaaata
    94261 aatgtcatag aaaatcaata atttaggtag ccaccatgtg tatgcagtag cgtgtcttct
    94321 tcccttgagg ctttttgttt ttcgatacgt tcttcttccc aaacagacaa cgctactaga
    94381 atctctctta atgattttcc ttcttcggtg agcgagtact ctactttagg cgggacttgg
    94441 ttataggctt ttcgatggat actttcatct tgttctaact ctcttaactg ctgggtcagc
    94501 atttttttgt gatcgtaggg atttgcttgc ttctccacgc ctaaaataag cgatattgct
    94561 cttcccttta tctggtgtaa gcaaagcagt tagcattttg acgatcgtgg gttccgcttt
    94621 tcacttctta tctacttagt atcatgaagt atactttcgt actaatacta agtagcggaa
    94681 gtgtcaacta ctttgtttaa ctacatagca aaagaaacag aagggtgaca acggtcatca
    94741 cgcttctgtt tcttttgaat atgctgtgtt gttgtctcta tctccgtgta gactttcctc
    94801 aaacttatcc tttgacagta agtcagtagg ctgatttgct ctttctagat gccagataca
    94861 tttctacaaa aaaatagtga ttctgttttg aaaattcgat ttttagttct gcattttcgt
    94921 aaacatccaa catttttttc gcactgtata gacctaaccc gccatttttt ttagaggttt
    94981 ttcctctttt gaccatctcc gatagcgtca aattcgttgg atttgccttg ttcgctatac
    95041 taaaacgtga tccctctttt tcttccagca gattgatcgt aatcggactc tgatcggcta
    95101 cacgatgatc gaatgcgtta gaaataaaaa tagataaaca gcgaataaaa acaaccagat
    95161 caatcgggat tgttttcact tcgacaggaa taactacttg gatcgggatt ttctccgatt
    95221 ctgctttttc tagaaatttt aaaaagacac ccctgacagc tggggataca atatttgtta
    95281 gctgttgtat ttgcggtttt tcaaaaatag ctgcagaatg atcttctaat atttctaaaa
    95341 attccaacgt ttctttttta ttttcctgaa gagtaatttt taatgaaaac agtagacttt
    95401 tataatcatg tttgaattcc tctagatgat ggtaatattc ttcatttatt tgatacagtt
    95461 gaagcgattc ctgatgttgt ctttctttta cttggaaact gatcaacata atggaaaaaa
    95521 acaaagaaaa aaaactgatg actatcgaca aaagagatag aagcagataa ttagatgagc
    95581 ggaagtgaac acttcccaat accaagtaaa tcacgcccca gcttaataaa atacaaatac
    95641 ctccaaaata gtgttcagtt ggataagtaa aaagcaagtt gagaaatctc gtctgtttgt
    95701 ctatactttt tactaataga tagaaaataa atgcgataag tagtgcaaaa aaacttgctg
    95761 ttccaagatg tctctttcct aaataatcca tcagatcaaa aaccagaaaa aagctgagtc
    95821 cagtgatagc aaaaaaaaga ttactgatca aacagctgat aaacaggttt ttcgtagtaa
    95881 aataaaaaag aaacatcaat aataagccaa ttaggtaagg aaagctcact ttagggatag
    95941 gaagtaaaag tgtcaccacc atcaaagcta tacaaccaaa gctgtttttt actagcagtt
    96001 gtttcgaaaa gaataaatag atacctaaat ctaaaatcaa agtaaaggtc aaataaagtg
    96061 tcactgttgc gaccatctta ttcctccatt gttttgtttc aaaatgtaca catatttttt
    96121 taataggagc ctgcatatga aaaagtattt tatcatagaa gataaccagt ttcacagcga
    96181 atggatcatc agagaattgg tcaatcatca tatcgagaat atcgtgcagc tcacttctat
    96241 ctctcaaatc aatcagttga tccagttggg cactattgat aatcacgatg ttttctttat
    96301 cgatatcgac ttgaagcaat cactcacagg tattgatgtc gccgaacaaa tacgtaaaaa
    96361 aaatgcacat agtaatattg tttttttcac cgcttatacg aattttgcag tagagatcat
    96421 caatcggaaa atccttccga ttggatatat cagaaaagac aggaatttat ctgaacaaat
    96481 tcgtcaagtg ctagaacaga tcaattggaa agaacagcag atcgtaaatg tcgataaaat
    96541 ctttattgat caaaaaggtg gaagtctcgt cctgtatcct cgggaaattt tatatattga
    96601 aagtatcaaa ggtttgaaaa accaagttat ggtcaaaaca actacagaag ataaattagt
    96661 gaatacttct ttaaaacaat tgaagacaga gttagaaaag tatgcttact ttttactttt
    96721 aaaatcttac tgtatcaact tatcgcaatt gcagaaaatt gattctgctc attatgtgtt
    96781 agaatttttc aacggtgact ccttactcgt tggtcgaaag atctttgaaa agacaaagga
    96841 acgtttccat gacttccaaa aaactgcttc gagttgatga ataagagctg agacgtaagc
    96901 atagcagatt tcagggagtg ggccttgaat cggctccact ccctgaagtc gttgatatga
    96961 ttttacgctt cctcttctgt aggagcatct gttaacgacc atgtgaatgt tgaaacgtag
    97021 ttgtctacag cataattgga tacaggaaca aataattcca ctgattgtct cccttgttcc
    97081 acattctctc ctaatgaata aatccatgtg ccaatccctt catttgctcc tgcagttact
    97141 agatctactg cctgatctgc tgggatttcg attccttcag cgccagttcc agaaacggta
    97201 gatggcattc cactgctatt agttgcgcta tttcgaatca cggcgttttt gaatttcacc
    97261 tttgaaccag ttagtttatt cgtatcagat gttgtaccaa taaattctgt tcgtttgact
    97321 gataatttcc aaccggcata atttccgctt ttatccgtta cttgtacgaa attctgtact
    97381 tgtgtttgtg ctccagtact gtccgttccg ctttgtaatg cagcatatac tgtttttgct
    97441 gtacctaact tgattgttcc aaaatcaaga tctggagctt ggtcaatcgt cagtaatccg
    97501 gatgttccct gatttggttc gtcaggtgta aaaggagtat caggatcatt tggatcaaca
    97561 ggaggaactg gaacaacgtc ttcaggattt gcagcatctg gtttggtcac agaaatcgtt
    97621 ccttctgtag tggctgagct cttattctca gcaaaaacac tttgtgtaca taataataga
    97681 cttccagcta gaacggtact taatgcaatt gtttttttca tttctttttc cttctttctt
    97741 ttaaaataaa taatccagca aataagccaa taagaatgac tccaacaagt atcagccatc
    97801 gccagtcaaa tgtttctggc tgatttttta aatcaatatc cttttcattc aattggtccg
    97861 ctgcatcatc agttatttca aaatcggtat ggagattcca gcgtttttct ttccaagcac
    97921 ccttcacaac cgcttgataa tgtcccggag ctaatttttt tccttctaat gggacaagta
    97981 aatcaaaatt tgtattgggt gctacatcta ttttttcttt ttttattgaa aggtaaggct
    98041 cttttgtttc ttttttgtag atttcaaccg atgtagtcaa gccgaacata taagaagcat
    98101 ttggattttg aagattcgcc ttaatcacat ttcttccatc gctttgatcc gcataagctt
    98161 tttttaattt caaatctggg gaagactctt tttcgctatt tcaaatcaag attgctttca
    98221 cttgagaaaa ctgattgacg acaccaactg tacttttgtt agaaacgttc tctttttttt
    98281 cttgaaacgt gatccctcct gcgaccacac cagccagctc tttttctggc gctttcagtg
    98341 aaagtgtctc agtgaccgca ctttgaggag gaacagttat ttctcccact gtttttgcta
    98401 agtttttcat atcataactt aatgtttcat caaatttact ttttgattct ccatattcga
    98461 tcacaccgtt tgaattcgtc gtagcggagt ggatcaatgt ctcaactgtt actgatttat
    98521 ctgttcggtt aaagaccgtg taggggattt cctgtgtttt cccaggctcc atccttacat
    98581 ttatatatgt tttgttctta tcaatctgat tagccggtaa ttcaaaatct accgcaaaat
    98641 tgaattcgga ggcatggaca ggtgtctgcc aaaggatgaa tccaaggaga aggatcataa
    98701 gtaaagagca gttgtttcga tgacttttat tccatattcg attcatcaat catcctcctt
    98761 gatctttatt ctgtcggcgc atctgctaat gtctatgtta tctctgctga gtaattacca
    98821 gctatctgat tttctttggt taagacaagt ttaaacgccc gaccgttatt taaatattct
    98881 gaataatctg cttgcacatt cgttgaattt tgtcctctga caatttccag ttcttcttca
    98941 ttcactaatt gatactcctc tcctttcttg aaatatagga catcctgcat agaaaatcct
    99001 gcatcatttg tgaaaggctg agataatttt atcgttaaga tccacggatt tttcgtttct
    99061 cgctgatcat aaatccataa tttttcctgt atatccattt ggccaaatgc ttcttgtgtc
    99121 aaaccagttg ctttgatctg accaaaatcg agtttggaag gggcaagaaa tgagagacca
    99181 ccttctacta cgatcttcgt agcaggtgca aaaggcgggg catcatgata aacaactggc
    99241 gtatcacttg gattgtgatt cccaatttca tcgttggtac ttggcttgtt ctgcacaccc
    99301 ttagcagtag cttctcctgc ttggtcgttt aatacaattt ctaatacatc tcctgcaaaa
    99361 agttgatttt ctgggataga aagaacaaat tcccctgtat catcaatagt tgtttctgac
    99421 aaaacagctt gatttttttt caatgaaacc aaggctcctg cttcacctgt acctgtgatc
    99481 gtgcgagaag ctgcattgat caatgtggta cttaaattag caggttcagg aggaatcaca
    99541 tcgactgtcg ttttggcaga gtccagttct gtcacttctt ggccacctct tactttttta
    99601 gcagcaacaa cttgcacttg atcctccgtt tttaatctct catcattggg tacttgaact
    99661 tcgaacaagc cgccttgttc gccttctccc catgggttat atcctgcccc ttcattttca
    99721 tctgtttgtc cttgcgtgag agcagtaatt tctacagatg atttcgtcgt atctgcgtaa
    99781 gtaatacgta aagtcacttc tacttcgcct gtccaagcat ctcttggctt tgcctcgaca
    99841 ccttcgggaa caacgacatg cccatagatt tttttatctg cattcgttgg cactcttaag
    99901 gattcaatca tcgggagctg attattggca ctgattcgat tataattttt cattccggca
    99961 cctgtctgag caaattcatt tgttaaacct gcactagggc ttgatacgaa attgcctaag
   100021 tcggtcccat tgatcgataa gtctgtcata tcagaaaaat aatccgggtc tttttcaaag
   100081 ttatcgaatg ttgcgcctgt ttttcgccat aaagcgattt ctgaatgggc gatctttaaa
   100141 gaagaatctc catttccttg gaatacccag ccgcctatgc cattggtctc gcttccaatc
   100201 cgtttgtttt ggaaatcaaa ataggtagga gattctaagt ccacattcaa cacatcccca
   100261 ctgatgatgc cggtcttatc ttcccctgtt ttcccgacca tgactaaata agttttttca
   100321 cctgccgtaa aatttaaatc aatatctcca gttgtatcta cagttgctcc ggaatctgcg
   100381 cgtatatcga tatttgattt ttctccagtg actgtaaaat cagctgaacc tggactttct
   100441 agaaaaccag aagcgtcata aaattggatc gcttgatttc cttgattgag tctgttcacg
   100501 taagatttgc catcacctgt atttcttacc ctcaatgagc ctccattggt tactgtcagc
   100561 ttttgcgtac cattctcaaa acgaactgcg ctggaacgcc cactctgctt atcgatgtcg
   100621 ataactgatc cggctccttc tacgatcaaa gaaaggcctt ttcctacaaa acgcatccca
   100681 ttgttcccgg gttgatcgtc atctccagcc attttgaccg agatttgtcc accacttgat
   100741 acatggattt gactagaatc tccttgcaag cgaaatccgc ccgtagttgc tgtattgatg
   100801 gtgattttcc caccattcga tacagtgact ttcgatcctg aacctctcat ttggatgatt
   100861 ccgcgattgt tgtcattggt aatattgatc tttgtattta ccgaaaattc gcttcccgaa
   100921 ccactgactt caaacatgac attaccaggt agcgtatcga ctgcctctcc ttcatcgcta
   100981 acgccatctg cccgatcata atcaagagag acctttgaac cgcttaagat atggattcct
   101041 ggcgctgttt ttccactacc agtctcatct cctgaatcta gaaaaccgta gaatttccct
   101101 agatacggtc cataaagttg actaccattg atcacattca attgatagct tctacaaaaa
   101161 taggctttac ccggagcggc attcagtcct tccttcactg gttggacatc caacacaccg
   101221 gaaacaccat ctaatgtgac agttgcacga ggagcgtaaa tcagtcctaa tttggaccca
   101281 tcatacaaat caagtgtccc ggtaaatttt atttctcccg taaaatgata tctgcttccc
   101341 caaaaatcgg tcatataagc aatgataatg gcatttccat cgatatttgg tgtcaatcca
   101401 cctggatgtg cagctgttcc tttaaaattc tggaactcga tcgactgagg tatctcattg
   101461 atataaatat ggtgtgtgcc gaaattgtga gcgaatccac caaaatcaat aacgatatct
   101521 cgtttgatct ctaattccct gtctaaagtc aaaggctgaa tcagtcggat cttagttact
   101581 gattcgtctg cgagaagctg cgccagttct tctgttgtgg cagcttcgct gtacccatcc
   101641 gctgaaacag ctcttgccag tgccgcttca ctgctatcag acgtttgttc agctacttct
   101701 gaggtctcac ttgtcttatt ttcttcttgc cttttattag tagaagcctc actttgagat
   101761 tctgtagttt cagaagtaat cgattcttct gaaaaagtag tcttgtcaaa actttgattc
   101821 tctgattgcg ttgattcgtt tgttttctct acatcggcaa aaacggatgt caccatcaag
   101881 agagggaaga caaacaaaat cgacgcaatc agctttttta cacattgatt cattctccac
   101941 catcctctct gacgttttga caattttatt ttatcgtttt aatctatttc caattgtact
   102001 ttcatattta aaatatgtat ttttatggaa aaatttttct attaggtgta aatttctttt
   102061 ttgtacaaaa aaaaggctgt gacaaaagtc ttgtcacagt cccttatccc gaacaagcgg
   102121 tgttctcccg ccaactcctc ggtcacaacc tccattttaa caataaacct gtaaatgtga
   102181 gggcaatact ttgattgtca caggtaattt atccccttca tctccatcaa cattcgtcgt
   102241 caattcttcc tcatcagcta atgacacaac taattgctca caagtaaggt aggctagatt
   102301 tttcgtagat tcatctactc cttttaatag gtctggcaat gttttaagcg tatcgatcaa
   102361 agaagaatct tttaaataaa ccaaatggag cttaccatca tccacttttg catttggaag
   102421 taatgtttca aaaccgccga ctgagttagt tagtcctatc agcaaggtac tgctctcaat
   102481 ttcttccttc tttccatcaa cttctacgtg aaacgagtag gattgtgtgg aagctaactg
   102541 tttgattcct gacatgaaat aagctagttt tccaaatttc gtcttcttct ccgcatctac
   102601 atcattgatt gattcaggga tagagccaat tgcgacgaca ttcataaaat agtcgtcatt
   102661 tatttttcca atatccaatg gcttgactga ttcaatcgaa aaatgattga tcgcttcctc
   102721 aggttctagc ggtatcccta atgctcgagc caagtcattc accgtaccca atgggaaaaa
   102781 tccgaaattt ggccgatgtt cttgttcagc gattccactg attccttcgt tgactgttcc
   102841 atctccgccc atgacaaaca cactatgata cccttccgta gccgcttcgc gagtaaagtt
   102901 ttttgcatcc cctgcttttt ttgtatgcaa gacgaccact tcatcaaaca ccgattccaa
   102961 ttttgctatc gctaattgct caaattcctt tgcttgttca ccgcctgaac tggggtttac
   103021 cactaataaa acttttttca tcactttctt tcccttctga ttgatttctt taatataacg
   103081 atagcataaa gaaaaaaatt aggctgtgat gaagtactgt tcatgaaaca ttcatttatt
   103141 ttttgacaag ataaaacatc catactatga aactgaggaa aattaaaaca atgatatagg
   103201 aaataaaaga aaatgatagg cattgtatac ctaataaagt aaaaatctta ggtggcagat
   103261 aaaaacacaa aaatagcaag agaatgtaat agcgtttctt ccactttttg ttatcagacc
   103321 ttatagcgat cagaggaata ccaaatgcat aactgaaaaa ctcttgatgt actgttaata
   103381 tgtcacggcc ttgaataata aatgcgacaa tccccgctat aattagtgtg cctaacacca
   103441 aaacggaaaa ttgatgaata tattttatat acaaatgatc cattgtactt cctgcctttt
   103501 tatttgtgag aaaaacaaat ccgtatacgt gaataacttc tagaaataaa agaaatttgc
   103561 aaaaccactc catttatcta cttctacgtg cattttttga tattgttttc tttatttaag
   103621 attatacaga aaaatatcta gggtcgctgg attctaagta aaaaaaattt ttaaaataaa
   103681 aagaactaaa tcaagtagta attaaactac tgttgattta gttctaataa aaagatttag
   103741 atgaacagtt ttattgattt aaatagttca tattttttat ttataccgct tatttactac
   103801 ttgctgtact agaatctgaa gtgaatgtac tcaaaacatt ttcaaagtct ttgtctttga
   103861 tttttacatt agcgtctttc aatacttcgc caattacttt attctggaag gtactgtcac
   103921 ttaattttgt gtctgttgca atttctttca attctttttt gtatttatcc atgtcgttgc
   103981 ctttgttttg gtttttcacc attttaacca cataatattc cgtagtataa gttgaagcat
   104041 tggtagaagt gatcacatca gaaacttgac catctttcaa cttaaaggct gcttctttga
   104101 cttctgccgg aaccgttgta gtagtggaat caaatttcac ttttccgcca tcttcttttg
   104161 tcgtagtatc agttgacttg tctttggcta atttagagaa atcgtctccc ttatcagcag
   104221 ctttcttcac atcttttgca tcatcttcac ttgctacttg gataatttga gcttccactt
   104281 ctggatggaa agattcccaa gccgttttta aatcttcatc ggtcaatttg atatgtttct
   104341 ttagaccttc ttgaaaggct agactttgtt tgatactgtc tttgaatgtt tgttctgtgt
   104401 aacctgcaga tttcaattgt gaatcaaatg aatcacccaa ttgtttcttt gtttgatcat
   104461 attgagaatc gatttctttg gttgatacgt catctccata tttatcttca aatacttgat
   104521 aaacgatcaa ctgttgcaca gcggaatctg ctccttgcat ttttttcaag ctatccatta
   104581 cttcttgttc gctgattgta ccgcctttat aactaacggc tgttttttca ccggcattcg
   104641 tacagcctga caataagcca gtgcctagta cgatggcaag tgctaaaaat ctttttttca
   104701 tttatcaatt ctcctacttt tcgttttttg cgaattgcta aaaacaaagg tgttcaagat
   104761 gaaaatcatc aagaacacct ttactaatct gctcgatacg tcctgaatag atataaggct
   104821 acacaatcca gaaagttcgc tcagcagaat aaatgtcaag tagcacatca caccttaata
   104881 tactacttct tttgttaccg tttttcaagt ctatcttgcg ttccgtattt aacgtaacta
   104941 attcttagaa caaatgttat cgattttgtt tttcttcttc cgctgctggg atattcaaat
   105001 cagacacttt tatgttcgat tttccagaca tttttttgtt gtttttatta tgatatattt
   105061 ttatacaact aaaaatgaat atattaaaac taccaaaaat aacttttaac gctgtttcat
   105121 tatatgtttt ttctatttta tataaacttt tggatactta ataccaaccg gttggattgt
   105181 accaacatga gaatgtgtca gttctatttc ctgtcgcact tgcataggcc catactcctt
   105241 ttgttgcatt tgctgatcga atagagtttc caactttcgc ttttgcaccg tgacgattat
   105301 agacacgact atagtggtta gaatgacctg tttttctcgt acaagttgta tcactataat
   105361 aaacccatct tccagagcta tgattaattg ctgttctaga aatttcccgg tctactggta
   105421 aatttgactt aataatatta cctttagcat caaaatgaat ctctcctggc tttaaagatt
   105481 tgtaatagat ttcaccgtga actgaatttg cttccacttc agatgacata gcgtttcctc
   105541 caacaaaacc tatccctagt gcacaaataa taactgcttt tttcataaaa cgacatcctt
   105601 tcctttttga tttttaaagc atgatcttct tgtttcctat tttggtcaga tatggatcat
   105661 gcgtgactac gataactaac gtaccttggg aagcttgttg cgataagatt tcaactactt
   105721 tatccttatt tcttttatcc aatgacccag tcggttcatc ggctaaaatg attttgctat
   105781 tcttcaataa gactctcgca caggcgattc tttgcttctc accaccagat aatgtgtaga
   105841 taggcgtact tagcttcttg tttatattta cttttttcaa tgcctcatac tttgctgttc
   105901 gcttatctga aacatttaaa ttcgaaaact tcaatccaat atctaaatta aaatcgattg
   105961 tttcatattc aatcaaccca aaatcttgaa aaagaaaaga tatggtattt ctttttatca
   106021 agcgcttctc tctcccagtt aattgtttcg tctcttgatc gaacaaatag aattgtcctg
   106081 aactgaactg atcattcaat cctaatatat tcaataacgt acttttacct gctccacttt
   106141 ctccaacaac agtcacaaga tccccagcat ccgcagtgaa acgatccaaa tgaagaatcg
   106201 ttttgtttcg aatgattttt ttcgcacctt ttatcactat caacggctcc aattgttaac
   106261 ctccattcat cagcaataac tgacttttct tttctgtaga caaaataaaa acaactgaaa
   106321 gaataaaatc aatgaagcta aagaaaaaaa tattaaaaag atatttaggc tctctttcta
   106381 taagaaaaag gaagattaca cttgtcgttc cccatttgat gaggttcatc atgaagaaat
   106441 ctttatacgt ttcaaagagc gaataaccac ttgaacgaaa gatagcgatt ttccgacaat
   106501 tgtagacaaa atatatgcat aacatgacat agctcaacaa gaagaaagaa aagaaagtga
   106561 gtaaaaatat ctgtatcaag taatgaaatg atctgcttaa cactttgaca gctatctctt
   106621 cagtctgagt atacggaaat gataactgca agttatcacg taactgactt tcttcaatca
   106681 gctcaaataa cctttctttc gacaaagagc ctatcttgat ctttaacggt ggatagattt
   106741 ctccgctgag aatatttctt tccaaataca tactgttttt caatgtcagt atttcaacaa
   106801 ccggataatg ttcgatccag gggatagaag gaataaatgt ataaatgggt tgattgtttt
   106861 ttataaatag aaatttcggt tctttttcac tgatttcttg ataatattct gttatttgcg
   106921 ccaggtcatt ttttaaatct gtatgtctat atcgttcagg gatcaatata acagggtgcg
   106981 tttctttttc ggttatttgg atcaaccttc cagagacatc aatcaaagga aatttcttaa
   107041 gataattcag atttattttt atccctctgc caaactgttc attttcttca ttcaagtaat
   107101 ctgatacatt gactaatata cttccgtttt tattcaaagt ttcatataat tcctgatctg
   107161 ctgctgatgc aaaacgattg gaataaataa aatccacgtg gtttttcccg atggttactg
   107221 gataaaatac atgatagtcc tcaccagcga tttcttttgg tggttcatgg gaaacagcta
   107281 actgtgaaga agaaaaaacg atagttgcta attcgacatt ggcaacggtc aaaagaagag
   107341 aaaacaacaa tccaaatgta aaaagaatgt attggatata gttgaacgct tctcttaacg
   107401 aagcgatttt ttcaactaat aaaagagaaa tcaaagagat accatatatt ccgctgaaca
   107461 agaaaacgta catctggaac aaataaagaa attgctcctt ataatacata aaaataaaac
   107521 caccaatgat tcctgcaatt atgaatgtaa taatgatttt ctttttcccc aataaacacc
   107581 acaatacttg atgtaatgaa aagtcattat tcaacaataa actgatttct ttattcatca
   107641 ataagaaaaa ggatgataac aaaaggaata aaagaatcaa tccaatagtt aaatacactc
   107701 gataattata tacgtctgta tttgaaataa ccgaatacga atagctattt tcaaagtctt
   107761 caaaaatatt agtggcataa tcagtgtgaa atgcttgatt gaatcgatca gtgaatagtg
   107821 aaatgacccg ttcataggct tctttttctc tcgtcatcaa gaaaaattca ccttcaaaat
   107881 cttttatttt gatcgattct tcaatggacg ttacgcgaaa ggaggtatta gaatagggta
   107941 ccttctcgtg agaagatttg acatcccctt gataatacaa tgtcatttca agctttggct
   108001 gtatcttgaa gttccaagat gtatctactt cattggattc atttactgtt tttttcatat
   108061 aagaaagctc agtttctgat gagacatttt caaataccat gattagctgc tcatattctt
   108121 cttgcccaat aaaatgttgt ggcaatcgaa tcggagtata agtatctgtt tgatggaaaa
   108181 attcatttgt ccgatagagt acctgtttat ttatactaac caaggcaaaa ccactcatga
   108241 taccggtcac tatgattgtg agtaaaactg tgaacttttt tttgattatc accactctcc
   108301 cttacttaaa tgattctttg ataaaatcat accgtttttc atcaaaaaaa cgtatctatc
   108361 aagtgtatag gtcatgtaga ataaatctat atactgtaga atcgaaagga gaagaagatg
   108421 aacaccggag aaaaaatacg aacttaccgc agaaattgta agcttacgca aaaagaatta
   108481 ggcgaaaaaa ttggtgtttc cgataaaacg atttctagtt gggaaaattc tcgtacaatg
   108541 ccagactttg aaatgctgtc acttttacat catactttag gtctgccgat tgattttcct
   108601 tctattgaat cagctaccga atcaatagaa ccaacattgc cagatgaacc tcttgttaac
   108661 aagaaatctt attcatcaaa acaacccttc tcactcaaaa agacactatc tttctttctg
   108721 ctcgtctttt gtttggtcta tctttttctt atcaattatc aatacaaaaa tgaaacgatc
   108781 gatcgattca atcctttttt gaaaccacaa atcggctata ccacactccc tgtaggatac
   108841 gtggacaatt ccatcgaacg ttgggtatgt aatgatatct ttggccatgg tacatggctg
   108901 tcttttcacg ctggagaggt agaaaaagag aaaaaccatg ctgtaatcaa acacaaagga
   108961 aaacacgtca tgaacgttcg cctgctcact tgggaagcca ttccctcaga ttaccaagaa
   109021 atcctcagcc aagactatga cgacgcctta aaaagaagcc ctcaggagcc agataggcat
   109081 taagtaggag atgaacgtag agatagaaaa aatcaatgca catgatctta tccaaaaaac
   109141 aggggtacaa attaattgaa aaagccttga gatgaaagtt cctaaataaa aaagttcaga
   109201 atgataggta tttctggctt atagtataat atttacgcca cagccttcca atgattcttt
   109261 ttggaatcat aatcaaggat ggacattcac aaaaatattt tgctcattcg atccgaatag
   109321 attaacgacc aatctagtaa gtaatataga ttggtacgta gtcaagctgc acataattta
   109381 gatcaatttt agttcttttt tatatttcta tgatctgctc atttactttt atatgatggc
   109441 ttacagtaac ataaataaat atgataatcg ctggtagttt atccaagagt actcaataaa
   109501 atacaaaatg gattgttcaa gcgcctatca taatgataaa atgaaacaaa taaacgatac
   109561 aaggaggaag agactttgag taatggcaga acaatttttt cattgtaaaa attgttcagt
   109621 tgttaatcta tgggatttcg gtagcatggg cattttttta tagaggaatc acaccaacct
   109681 ggccgtttta tctcttgtta gtgggaatat tagtaggaaa ttttgcccct cttcactatc
   109741 gtacgaactt ttttccaact gattctggcc tttttcttaa aacaaagacg cgaaaattag
   109801 aaaacattat tgaaatgaca attacctgta taatcatttt cttagttata ttcctaaacg
   109861 tcttctaata agaatctctt aaaattagct tgttacagtt agttacctag tttatataac
   109921 acagttatct tatcttcctt atcaacatct tttgccaact ctttgtctta aattcgaaac
   109981 atataagcag agctacgaac accaagactg tttcggctct gttttttgca tcaaattcac
   110041 tcttatatag ctgataatct cggctcttta aaagaaatta ttttcgcttc attttattat
   110101 aaaaaggcta ggaaccttga tgttatcagg ttcctagcct ttatttaagt attaccccac
   110161 agacccttcc atatagattt tcaaattaca cactagttta agataaaaca aacaaggaaa
   110221 aacttaccat ttactcaaaa aattaactca tataagtaca ttagaatgta aaatagactg
   110281 gtcaaaatct ggtcaaaaaa gtagatgtga cacaagttcg cattcaaagc gatgatccat
   110341 gatttcgtaa tggtcaatta tatggatcaa agccacgcga caagagcgca atggatgtct
   110401 ctaccgattg gttgaataaa cgaaataaat agaatgtgaa aaaggatcgg acaaatgttc
   110461 cagtttgctc gatccttttt tatttgaatt cattttcgct ttatcaaaca tcatttgatt
   110521 actcagttaa atacttttga catgagtacc aatgaaacat ttattcatta aaattactta
   110581 tttcttatcg cctttctagc caatgccaat ccgccgatta ttccagcact atcacctaat
   110641 tcgggcgtaa caatgtagct agcaattggt ggtatttcaa catatccatt tataagctca
   110701 acaaatttat cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa
   110761 ataattctat ctggcgaaag catcagtgtt gtattgtatg cacattgggc aaggtaaaag
   110821 gcttcaatct gccaaaacga atcgtcagcc aataaattct ggccttttac acccaa
//
LOCUS       DAPBBV010000004        99944 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.004, whole genome shotgun sequence.
ACCESSION   DAPBBV010000004 DAPBBV010000000
VERSION     DAPBBV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 99944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 99944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..99944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.004"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(554..2167)
                     /locus_tag="RD486_000369"
     CDS             complement(554..2167)
                     /locus_tag="RD486_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7662134.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..3216)
                     /locus_tag="RD486_000370"
     CDS             complement(2308..3216)
                     /locus_tag="RD486_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7662135.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3399..4523
                     /locus_tag="RD486_000371"
     CDS             3399..4523
                     /locus_tag="RD486_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7662136.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4750..5667
                     /locus_tag="RD486_000372"
     CDS             4750..5667
                     /locus_tag="RD486_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7662137.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5660..6493
                     /locus_tag="RD486_000373"
     CDS             5660..6493
                     /locus_tag="RD486_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7662138.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6576..7694
                     /locus_tag="RD486_000374"
     CDS             6576..7694
                     /locus_tag="RD486_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7662139.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7688..9586
                     /locus_tag="RD486_000375"
     CDS             7688..9586
                     /locus_tag="RD486_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HDT7662140.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9580..10803
                     /locus_tag="RD486_000376"
     CDS             9580..10803
                     /locus_tag="RD486_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7662141.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10889..12823)
                     /locus_tag="RD486_000377"
     CDS             complement(10889..12823)
                     /locus_tag="RD486_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7662142.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13049..13705
                     /locus_tag="RD486_000378"
     CDS             13049..13705
                     /locus_tag="RD486_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDT7662143.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13779..14132)
                     /locus_tag="RD486_000379"
     CDS             complement(13779..14132)
                     /locus_tag="RD486_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDT7662144.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14324..15253
                     /locus_tag="RD486_000380"
     CDS             14324..15253
                     /locus_tag="RD486_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDT7662145.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15264..16100
                     /locus_tag="RD486_000381"
     CDS             15264..16100
                     /locus_tag="RD486_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HDT7662146.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16348..17124
                     /locus_tag="RD486_000382"
     CDS             16348..17124
                     /locus_tag="RD486_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7662147.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17300..18043
                     /locus_tag="RD486_000383"
     CDS             17300..18043
                     /locus_tag="RD486_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662148.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18036..19616
                     /locus_tag="RD486_000384"
     CDS             18036..19616
                     /locus_tag="RD486_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HDT7662149.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19867..20346)
                     /locus_tag="RD486_000385"
     CDS             complement(19867..20346)
                     /locus_tag="RD486_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDT7662150.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20362..21114)
                     /locus_tag="RD486_000386"
     CDS             complement(20362..21114)
                     /locus_tag="RD486_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDT7662151.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21231..21301
                     /locus_tag="RD486_000387"
     tRNA            21231..21301
                     /locus_tag="RD486_000387"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21263..21265,aa:Gly,seq:ccc)
     gene            21662..22387
                     /locus_tag="RD486_000388"
     CDS             21662..22387
                     /locus_tag="RD486_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HDT7662152.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22642..22908
                     /locus_tag="RD486_000389"
     CDS             22642..22908
                     /locus_tag="RD486_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDT7662153.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22905..23336
                     /gene="ruvX"
                     /locus_tag="RD486_000390"
     CDS             22905..23336
                     /gene="ruvX"
                     /locus_tag="RD486_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDT7662154.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23361..23666
                     /locus_tag="RD486_000391"
     CDS             23361..23666
                     /locus_tag="RD486_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDT7662155.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23747..24892)
                     /locus_tag="RD486_000392"
     CDS             complement(23747..24892)
                     /locus_tag="RD486_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7662156.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24953..25600)
                     /locus_tag="RD486_000393"
     CDS             complement(24953..25600)
                     /locus_tag="RD486_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7662157.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25794..26087
                     /locus_tag="RD486_000394"
     CDS             25794..26087
                     /locus_tag="RD486_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662158.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26131..26442
                     /locus_tag="RD486_000395"
     CDS             26131..26442
                     /locus_tag="RD486_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662159.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26439..27063
                     /locus_tag="RD486_000396"
                     /pseudo
     CDS             26439..27063
                     /locus_tag="RD486_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27204..27362
                     /locus_tag="RD486_000397"
     CDS             27204..27362
                     /locus_tag="RD486_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662160.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27363..27725
                     /locus_tag="RD486_000398"
     CDS             27363..27725
                     /locus_tag="RD486_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662161.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27762..28610
                     /locus_tag="RD486_000399"
     CDS             27762..28610
                     /locus_tag="RD486_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HDT7662162.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28600..30075
                     /locus_tag="RD486_000400"
     CDS             28600..30075
                     /locus_tag="RD486_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HDT7662163.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30341..30748
                     /locus_tag="RD486_000401"
     CDS             30341..30748
                     /locus_tag="RD486_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HDT7662164.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30751..30966
                     /locus_tag="RD486_000402"
     CDS             30751..30966
                     /locus_tag="RD486_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662165.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30970..31350
                     /locus_tag="RD486_000403"
     CDS             30970..31350
                     /locus_tag="RD486_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDT7662166.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31484..31639
                     /locus_tag="RD486_000404"
     CDS             31484..31639
                     /locus_tag="RD486_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HDT7662167.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31708..32181
                     /locus_tag="RD486_000405"
     CDS             31708..32181
                     /locus_tag="RD486_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HDT7662168.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32178..33872
                     /locus_tag="RD486_000406"
     CDS             32178..33872
                     /locus_tag="RD486_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDT7662169.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33838..34023
                     /locus_tag="RD486_000407"
     CDS             33838..34023
                     /locus_tag="RD486_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662170.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34027..35202
                     /locus_tag="RD486_000408"
     CDS             34027..35202
                     /locus_tag="RD486_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDT7662171.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35195..36718
                     /locus_tag="RD486_000409"
     CDS             35195..36718
                     /locus_tag="RD486_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDT7662172.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36774..37058
                     /locus_tag="RD486_000410"
     CDS             36774..37058
                     /locus_tag="RD486_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDT7662173.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37045..37380
                     /locus_tag="RD486_000411"
     CDS             37045..37380
                     /locus_tag="RD486_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDT7662174.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37675..38301
                     /locus_tag="RD486_000412"
     CDS             37675..38301
                     /locus_tag="RD486_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662175.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39043..39879
                     /locus_tag="RD486_000413"
     CDS             39043..39879
                     /locus_tag="RD486_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDT7662176.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39944..40378
                     /locus_tag="RD486_000414"
     CDS             39944..40378
                     /locus_tag="RD486_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662177.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(40446..41768)
                     /locus_tag="RD486_000415"
     CDS             complement(40446..41768)
                     /locus_tag="RD486_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HDT7662178.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41922..43562)
                     /locus_tag="RD486_000416"
     CDS             complement(41922..43562)
                     /locus_tag="RD486_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HDT7662179.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43892..44362
                     /locus_tag="RD486_000417"
     CDS             43892..44362
                     /locus_tag="RD486_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HDT7662180.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            44991..46094
                     /locus_tag="RD486_000418"
     CDS             44991..46094
                     /locus_tag="RD486_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDT7662181.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            46378..47058
                     /locus_tag="RD486_000419"
     CDS             46378..47058
                     /locus_tag="RD486_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDT7662182.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            47148..48182
                     /locus_tag="RD486_000420"
     CDS             47148..48182
                     /locus_tag="RD486_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDT7662183.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            48196..48531
                     /locus_tag="RD486_000421"
     CDS             48196..48531
                     /locus_tag="RD486_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662184.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48515..50995
                     /locus_tag="RD486_000422"
     CDS             48515..50995
                     /locus_tag="RD486_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662185.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            51051..52610
                     /locus_tag="RD486_000423"
     CDS             51051..52610
                     /locus_tag="RD486_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7662186.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52607..53971
                     /locus_tag="RD486_000424"
     CDS             52607..53971
                     /locus_tag="RD486_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7662187.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLTRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            54142..55212
                     /locus_tag="RD486_000425"
     CDS             54142..55212
                     /locus_tag="RD486_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662188.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            55227..55895
                     /locus_tag="RD486_000426"
     CDS             55227..55895
                     /locus_tag="RD486_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662189.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55915..56493
                     /locus_tag="RD486_000427"
     CDS             55915..56493
                     /locus_tag="RD486_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7662190.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56896..57807
                     /locus_tag="RD486_000428"
     CDS             56896..57807
                     /locus_tag="RD486_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7662191.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(58063..58980)
                     /locus_tag="RD486_000429"
     CDS             complement(58063..58980)
                     /locus_tag="RD486_000429"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HDT7662192.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            59182..59619
                     /gene="zapA"
                     /locus_tag="RD486_000430"
     CDS             59182..59619
                     /gene="zapA"
                     /locus_tag="RD486_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDT7662193.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59677..60225
                     /locus_tag="RD486_000431"
     CDS             59677..60225
                     /locus_tag="RD486_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HDT7662194.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            60340..62700
                     /locus_tag="RD486_000432"
     CDS             60340..62700
                     /locus_tag="RD486_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDT7662195.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62787..63101
                     /gene="trxA"
                     /locus_tag="RD486_000433"
     CDS             62787..63101
                     /gene="trxA"
                     /locus_tag="RD486_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDT7662196.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            63283..65061
                     /gene="uvrC"
                     /locus_tag="RD486_000434"
     CDS             63283..65061
                     /gene="uvrC"
                     /locus_tag="RD486_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDT7662197.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            65206..66105
                     /locus_tag="RD486_000435"
     CDS             65206..66105
                     /locus_tag="RD486_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662198.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            66098..67360
                     /locus_tag="RD486_000436"
     CDS             66098..67360
                     /locus_tag="RD486_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662199.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            67523..69421
                     /locus_tag="RD486_000437"
     CDS             67523..69421
                     /locus_tag="RD486_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HDT7662200.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(69720..70439)
                     /locus_tag="RD486_000438"
     CDS             complement(69720..70439)
                     /locus_tag="RD486_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDT7662201.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            70776..71108
                     /locus_tag="RD486_000439"
     CDS             70776..71108
                     /locus_tag="RD486_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662202.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            71095..73098
                     /locus_tag="RD486_000440"
     CDS             71095..73098
                     /locus_tag="RD486_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDT7662203.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            73117..73587
                     /locus_tag="RD486_000441"
     CDS             73117..73587
                     /locus_tag="RD486_000441"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDT7662204.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73608..74192
                     /locus_tag="RD486_000442"
     CDS             73608..74192
                     /locus_tag="RD486_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HDT7662205.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            74207..75193
                     /locus_tag="RD486_000443"
     CDS             74207..75193
                     /locus_tag="RD486_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HDT7662206.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            75183..75494
                     /locus_tag="RD486_000444"
     CDS             75183..75494
                     /locus_tag="RD486_000444"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDT7662207.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            75516..77297
                     /locus_tag="RD486_000445"
     CDS             75516..77297
                     /locus_tag="RD486_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDT7662208.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            77290..78666
                     /locus_tag="RD486_000446"
     CDS             77290..78666
                     /locus_tag="RD486_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDT7662209.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLLERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78673..79308
                     /locus_tag="RD486_000447"
     CDS             78673..79308
                     /locus_tag="RD486_000447"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDT7662210.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            79338..80693
                     /locus_tag="RD486_000448"
     CDS             79338..80693
                     /locus_tag="RD486_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDT7662211.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80885..82279)
                     /locus_tag="RD486_000449"
     CDS             complement(80885..82279)
                     /locus_tag="RD486_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDT7662212.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            82371..83342
                     /locus_tag="RD486_000450"
     CDS             82371..83342
                     /locus_tag="RD486_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDT7662213.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            83339..84121
                     /locus_tag="RD486_000451"
     CDS             83339..84121
                     /locus_tag="RD486_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDT7662214.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(84290..84661)
                     /locus_tag="RD486_000452"
     CDS             complement(84290..84661)
                     /locus_tag="RD486_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7662215.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84795..85238
                     /locus_tag="RD486_000453"
     CDS             84795..85238
                     /locus_tag="RD486_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDT7662216.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(85281..86090)
                     /gene="yidA"
                     /locus_tag="RD486_000454"
     CDS             complement(85281..86090)
                     /gene="yidA"
                     /locus_tag="RD486_000454"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDT7662217.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(86109..87476)
                     /locus_tag="RD486_000455"
     CDS             complement(86109..87476)
                     /locus_tag="RD486_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7662218.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(87460..88290)
                     /locus_tag="RD486_000456"
     CDS             complement(87460..88290)
                     /locus_tag="RD486_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDT7662219.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            88453..88890
                     /locus_tag="RD486_000457"
     CDS             88453..88890
                     /locus_tag="RD486_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDT7662220.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88966..89586
                     /locus_tag="RD486_000458"
     CDS             88966..89586
                     /locus_tag="RD486_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HDT7662221.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89775..90281
                     /locus_tag="RD486_000459"
     CDS             89775..90281
                     /locus_tag="RD486_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDT7662222.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            90298..91197
                     /locus_tag="RD486_000460"
     CDS             90298..91197
                     /locus_tag="RD486_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDT7662223.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            91284..92168
                     /locus_tag="RD486_000461"
     CDS             91284..92168
                     /locus_tag="RD486_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDT7662224.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(92360..92431)
                     /locus_tag="RD486_000462"
     tRNA            complement(92360..92431)
                     /locus_tag="RD486_000462"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92396..92398),aa:Arg,seq:ccg)
     gene            92491..93825
                     /gene="rpoN"
                     /locus_tag="RD486_000463"
     CDS             92491..93825
                     /gene="rpoN"
                     /locus_tag="RD486_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDT7662225.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93974..95065
                     /locus_tag="RD486_000464"
     CDS             93974..95065
                     /locus_tag="RD486_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HDT7662226.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            95106..96107
                     /gene="gap"
                     /locus_tag="RD486_000465"
     CDS             95106..96107
                     /gene="gap"
                     /locus_tag="RD486_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDT7662227.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            96217..97407
                     /locus_tag="RD486_000466"
     CDS             96217..97407
                     /locus_tag="RD486_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDT7662228.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            97511..98266
                     /locus_tag="RD486_000467"
     CDS             97511..98266
                     /locus_tag="RD486_000467"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDT7662229.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            98382..99680
                     /gene="eno"
                     /locus_tag="RD486_000468"
     CDS             98382..99680
                     /gene="eno"
                     /locus_tag="RD486_000468"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDT7662230.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        33162 a        17067 c        20602 g        29113 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa aattttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataaaagg gaaggattat ctagttctat
     3061 agatttatgt gcaaattcag catataaatt agcgctttca tttattagta gtcgaaaata
     3121 gggagcagca gataaatgaa gatgggtatc tatggaatag gttagtgttt ttttgacaag
     3181 attggaggat tggttgtttg ttaacaaaag aaccactttc ctttctcttt ttatataaaa
     3241 agctttctat ttataattaa tgactattat aacaaaaatg aaaagccaaa acgacaagta
     3301 aaatattttt ttatataaat atttgtgtta ctaattccgt taatatacat aagtgaaagc
     3361 gttttatata agaacttgaa aagaaagaag ggatagacat gaaaaaaaga tacaaattgg
     3421 tgatagcttt gctaaacatt accctattat tcagcttaag tgcatgtgga aaaactaacg
     3481 aagaagtaac agcaaacatc gcagatccaa tgataaaaaa agccactaca ttagaagtat
     3541 atgtcgcaaa cggcaaactg acaaactatg ttgaaaatgc tgcaaaaatc tataaccgca
     3601 aaactggagc aaatattgac ttaaaaattg tgaatgtagc ttcgggaaca gcaacagtac
     3661 aaatgatcac cccaaaattg gtaacacacg aagatatgcc ggatattatc tccatggcag
     3721 acacttcagc agcaggtgtg ctggaaaaat ttcaagatgc tttttatagt gctgatgaat
     3781 atggatttta tgacaaatat ggcgatcagt tttatgatca aaaattgaat attttgcgtc
     3841 aacaaacgag taatgaaacg attattcctt gggctagtga ttttacccca gcactttgtt
     3901 attatcaacc aaaaaaattt gctgaaatag gtgtagattt tgaagaaatc agttcttggg
     3961 aagaatatat ccaggtggca aaagcattaa aagaaaaaac tggtagtttt ggaattgcct
     4021 tgccagaatc tggggaccaa gaattgttta tcaacatgct agcccagcag aatcaatctt
     4081 tgcttgatga agaaggaaat atccgtctga atactaaaga agcgaaacat gctgcaaagt
     4141 taatcaaaga aatgatcgac tcagatattg tacatttcta cggtgcacaa gatgctgaga
     4201 aagcatttca agaatctgca atgtttgttg ctggcggctg gtatgctacg aatatgtctt
     4261 tgaattttcc tgatgcatct gacaaatggc gcatggctcc actgattcct ttttcaaaag
     4321 aaaatccagg aaaaggtgca gtatcaggag gatcaagttt ttatgtccct aaagatgcca
     4381 aaaatccaca agtggcacaa caatttctta catttatgct gacagatgaa gaatgcttag
     4441 ccaacgcact ggagctgggc gtggctacat ctaactcatt ggcctatcaa acagaagcag
     4501 ctgagaaaaa gtttgactac taaggaggac aaaaatacta tgaactattg aataaaatca
     4561 atgaaaatac atcaaatact gttttaccag ccacttattc agatgctacg tcttatttga
     4621 ctaccgctgc atataactat tggcaaacag gtgattttga aaattcatat ctaaaagaag
     4681 cagaaaattt tgctcataag tacggcgtaa aattaactgg tgattaaaaa atattaggag
     4741 gacttaacga tgatgcaatc ttcgttacca agcaagacaa taaagaacag caagaaaaaa
     4801 gcaacagata cgtctcataa aaaaagtgct tatggattgg tcacaccttt tgttattttc
     4861 tttattgtga cgattttgat tcccatcatt atctcgtttg cttttagttt tatgaaaatt
     4921 ggctactcat ttgaatttgt tggatttgac aattatctag ctatcttccg agatccattg
     4981 tttattaaat cttacacgaa tgttttgatt atcatggcag gatcaattcc aataacgatg
     5041 ctattagcta tttactttgc tgttttattg aattcagcac agttaaaagg aaaaggattt
     5101 tttagaactg tctattatat tccaaccatt acatcaacgg tggctgtagc ttccgtattc
     5161 atgacttttt tcaatccgac tgggttattc aatggatttt tgaatgcgct aggaattaac
     5221 ggtgtacagt ggttaacaaa tcctttttgg atacgaatat caatgatcat cacgatgatt
     5281 tggcttagtg taggatataa cactatttta tttttagctg gtcttcaagg gatttctaaa
     5341 gagatatacg aaagtgctga aatagatgga gcatcgaaat ttcggcaatt ctttttatta
     5401 acgatcccca tgctaaagcc aatcatttta atggccacag ttttagccac tatcaatggc
     5461 ttgggtaatt tcaatatccc aaatatattc tttgggactt ccaatggacc agaaaattca
     5521 gctttggtcg taggagtcaa tttatataaa acaagttttg aaatggttga ttttggaaaa
     5581 gcctctgcta ttgcctggac gatggtgttt gtatctgtta tattatcggc tattcaattt
     5641 aaattcggag gtgataaaaa tgactaaaca aaagatacaa agcagaattt ttacgtacgt
     5701 cattattgtg tttggtgcct taatattttt gatgccatat ttatatatga ttgtagcttc
     5761 aacgcaaagt aatcaagaaa ttttaagtgg cggaatcaat ttcaagtttg gggatatgct
     5821 attaaaaaac tggcaagcca tcatggcgag atataattat cccttgatta tttggaattc
     5881 gattgttatt gctgtaatca gtacagtttt agctacagcc agttctacaa tggcgggtta
     5941 tgcattagca aagtatcgtt ttatggggaa taaactgttg ttcaatacag ttatgctatc
     6001 taggatggtg ccttttttta ccacattgat tcctttattt tacattatga gtcgtttagg
     6061 attatcgaat acttatgcag gtgtgatcat cccttcgatt gccagtacaa cttcagtgtt
     6121 tatgatgcga caatatagca gtcaatttcc tacagcactg atggaggctg ccagaatcga
     6181 tggtgccaat gagtgggtga tttttacgaa aatcgctgta ccgattttat cacctacgat
     6241 tattactagt ggtttactta tctttatggg aagttggaat caatatctat ttccattagt
     6301 catgctttca gataaagata aatatacggt tcccttaatt atcaaaaata tgacggtttc
     6361 tagtacaggt gagccaatta attatggcgc aattatgcta attttagcaa cttcagtgat
     6421 cccaatggtc ttgatttatg tgtgggcgca gtctaaattt aaggagaatg acattggagc
     6481 tgcaaataag taaaaaaaat aacgaatgtt aaccatctag ttcgttctag gagcaactcc
     6541 acattcataa aaattaaaag aatggcggga tatccatgaa tgaacagacg aaggaatggt
     6601 caagaaaaat tttgaatgta gcttctgaaa agatagatgc ggaattagac agaatgggga
     6661 ataaaattcc atatatttct tacaacggaa aatatacaga cgtaataaag gacagaggaa
     6721 tcgactggtg gaccaatggt ttttggagtg gtattttatg gcagctcttt cacaagacaa
     6781 aacgagaaaa gttcaaagag gcagcaatac aacaagaaca attattagaa tctgccctgt
     6841 accatttttc agacgttcat catgatgtag gttttttatt cttaccatcg gctattgcac
     6901 attatcaaca gtctcaaaac aaacatagtc gacaactagg gttacatgca gctacggtac
     6961 ttgctggacg ctataatatt tcagggaact atttagtagc atggaatgac cataaacctg
     7021 gttggatgat tattgatagt atgatgaatt taccattact gtattgggct tcgagggaaa
     7081 ctggtgatcc gaggttctct aaaattgctc ggcagcatgc agatacaaca gctaagtatc
     7141 tagtgaggaa agatggatca accgggcata tcgcagaatt tgatgcagaa tcagggaaat
     7201 atattcggtt acttggcggg caaggataca atgagaattc ttgttggagc agaggaaatg
     7261 catgggcttt atatggattc gcgttaagtt atcgttacac aaaaaatccg tactatctag
     7321 ctatagcaga aaagatagca gtaaatttta ttcagaaaat cgaaaaaact ggttatattc
     7381 ctctcattga ttttgctgta aaagattcga atattgatac cagtgctgga gtatgcgctg
     7441 catgcggtct tctggaatta gcaggatatg tttcctctgt acgatcaaaa atgtatcatg
     7501 aagctgctat caatatactc caaaagacag aaaagcacta tgcaaattgg aatatggatg
     7561 aagatgggat cattggaggc ggagcagaag cataccatag agaactgact tataatgtgc
     7621 cactgatcta ttctgattat ttttttattg aaggcttact tcgattagaa cagtcggaat
     7681 tagctatttg gtagtaaaaa gaggagaaaa tacaatgaaa catccagtac cactattaag
     7741 gaccagacag gattactttg acttatttaa aaagataaat caaccactcc agccgtttta
     7801 tcgagcaagt ggcgcacaaa ttgattatat acatcaaggg gtaggatatg gaaataaaat
     7861 tgcaggaatg gaaggattct ctcgggtttt atggggagcg gggcccgcaa ttgaccaatt
     7921 agatgaacga tggttgaaat taattctatc aggaataaaa gctggaacag atccttccca
     7981 tcccgattat tggggagaaa tacatgaaag agaccagcgt atggtagaaa tgcccgcaat
     8041 gttattagcg ttatatcatc atgaacaatt attatggaaa aaattagata caggagaaaa
     8101 aagccagatt attcattggt tctcgcaaat ttttgaatat gaatgtgcag atggtaattg
     8161 gcaatttttt aagataattg tcggaacaat tatccaaaaa tttggttatc cagttaaaga
     8221 atcagcactg aaagaagcat ttgataatat agaaaattgt tatcttcaaa atggctggta
     8281 tcgagacagt tcaagaggtc gccaagatta ttataatcct tttgcatttc attattatgg
     8341 tttgatttat agcgtactag aaccagaaaa gcccattagc cagatatata agaaccgagc
     8401 tattgatttt tctagagact atattcattt ttttgcggaa gatggtgcaa atgtgccttt
     8461 tggtcgaagc atgatttatc gttttgcagt ttcaagcttt tggtcagcta tgttgtgggc
     8521 cgatcttttg ccttttaaat taggtgaaat caaggggtta gtcaatcgga atataagatg
     8581 gtggatgcaa aaagaaatat ttgatgaaaa aggtatcctg aatattggtt atacctaccc
     8641 tcaattgaca ttgactgaac cctataatag tacgttatct ccattatggc tgaataagat
     8701 ttttttattg ttggcgctac ctgaagacca tgagtattgg acggctaaag aaatgcctat
     8761 gcctattcgt gaaggaacta aacttctttc agaagccaat ttgctcatac aacatgataa
     8821 tggacataca ttttttttga atgcgggaca attagggcca aatttccata cattgaccaa
     8881 tgaaaaatat ttaaaatttg cttattctag tcaatttggt ttttcgatac cgcgagcgaa
     8941 tcaattgaaa gcagaaatgg caatggattc aatgctaggg attcagcgag cggacacata
     9001 tatcacgacc agttttaaga atgagagcat caaaacctat ggacagttca tcgttcgaaa
     9061 taatgtacga gacattgtat gtaagaaaga ggtacttgcc tctacatggg aacctacttt
     9121 acaggcaaaa atcagaactt ggcttattcc ttttgaaggc tggcagattc gcgtacacaa
     9181 agtagaatta gatacagaat atgttctata tgagacaggg tttgctattg aatgttctcc
     9241 tgagaaagaa ggaataatca tagaagaaga caaggaaaac tatagggtga gtgaagctgg
     9301 cttttcaggt attatctgtt taagtgacga tactattaaa cgaaaatcca cagctattat
     9361 gggtttgccc aatacaaact tgatgacatg ggaaaacact tttattcctg gattagaggg
     9421 tacatttgga aaaggaaccc attggctcgg aacaggagtg gttgctcatc aagatcggga
     9481 ttatagttta gaagtatgga acaatcgtcc caaaattgat tttgatggga caaccgggct
     9541 aactatccaa aataaaaaca ataaaaaaag actaaaatta tgctaaaggc tggtggggaa
     9601 atgcttgata aagtgatgtt tgaagagata atacatccag aaaaatggat aaatgaatgt
     9661 tataaagaat taatggaaaa agaatggaat aatgagatcg agcgttgtcg cagacacacg
     9721 gagaggttaa tcaaacgtat cagtaacagt cagtatcaat tcccaagcga gtgtcctata
     9781 aaaggacgtt atccattaag agacaatatt ggttggacag aaggattttg gacaggaatt
     9841 aattggttgt tatttgagaa gacgggtgat cctttatttc aacaaacagc tgaaaaagca
     9901 gatatagatt ttatccacag gattgactgt caaattatca ctaatcatca cgatcttggt
     9961 tttttgtatt ctttatcaac cgtagcagat tataaaataa cgggaaatcg aaaaatgaag
    10021 gaagcttcaa ttgatgctgc agaaacatta cttcagcgtt tttgggagaa ggcaggagtt
    10081 atacaagctt ggggagatcc tagtgatcct tcacaacaag gtagaatgat catggattgt
    10141 tgcatgaatc ttccattatt gtattgggcg agtgaagaaa ctggaaatca aaaatataaa
    10201 aaagctgctc aggctcatat tcaaaatgca gcagattatt tagtaagaga agatggttca
    10261 acttatcata cattttatat ggatgtcaaa gatggaaaac caagatatgg aagtacgcat
    10321 caaggttata gtgataattc ctgttgggct agaggccaag catgggggat ttacggtttt
    10381 gcattaagtt atcgttattt gaaagaacaa aaatattttg atttaagcaa aatattagcc
    10441 aattatttta tgaatcggtt gccagaagat accatttgtt attgggattt gatctttgat
    10501 gattctagca gagaagaaaa agatacatct agtatggtga tcatggtttg tggattatta
    10561 gaattaatag aatcaggtct attagacaaa acagaaaaga acttatacca gtctgctgtt
    10621 tggaaaatta tgcgacaatt gaaagaaaga tatgctacaa cggaagaaga agatggcttt
    10681 ttaacacagt ctgtttataa taagcccaaa aataatgggg taaatacacc ttgtatttgg
    10741 ggtgattact attatttaga agctttagtg agaatgacta gtaattggtc ttcttattgg
    10801 tgaaaaaggt aaatatggaa tttttgtttg ataaaataaa aaaagaaaaa ccaaaacagc
    10861 atgaatggtt tctgttttgg ttttttcgtt aattttcata ttcttctaat tccaagctta
    10921 gttcttccca ttccgtcaat tttgtttctt gatcttgtct agcagcttct aaatcttggt
    10981 tcagctcatt gagttttacg tgatcttcca ggttttctgg cgcgaccatt tcttgttcca
    11041 actgatcgat ccattcatcg atccgcgcca tttcttcttc aacctgagta atttttcgtt
    11101 gaaggctacg gataagcttt tgctgttctt tgctttggta ataatcagat ttgttcgtgg
    11161 gagcaggagc agattctggc tcatcttgtg ccaacaattc ggcgatttct tcttcttcct
    11221 gctttttctc taaataataa tcatagtctc ctagatagac tttgctgcca ttttcagaga
    11281 gttcgacgac ttttgtcgcg atccgattga tgaaatatcg gtcatgggaa acaaaaagca
    11341 gtgtgccgtc ataatcgatc aatgcatttt ctaatacttc tttgttgtca atatctaaat
    11401 ggtttgttgg ttcatccaaa atcaaaaaat tttctttgtt catcgctaac ttggctaaag
    11461 caacccgtgc tttttcaccg ccacttagca gagggattgg tttttctaca tcttcgccag
    11521 aaaataagaa agcacctaaa gcacttcgga tctctttttc tggagtggta ggatgctcat
    11581 cccacaattc tgctaggatc gtcttgtttg tatgcagatc agcttgacct tgatcgtaat
    11641 agccgatggt gacatttgtc cctagcgttt cttttccacg gataaaaggg atctggtgaa
    11701 tgattgattt cagcaacgtc gatttcccga taccattcgg acctactaga gcaatcgctt
    11761 cttgacgacg gatatctaga ttgattggtt cagataaggt gacattatca tatccgatag
    11821 cggcatcttc gatttgcaag actacatttc cagaaggctt ttctatactg aatagaaagt
    11881 ttgcttgttt ttcatcccct tgaggacgat ccagccggtc cattttttct aatgtctttc
    11941 tgcggctttg cgctcgtttt gtggtagagg cgcgaacaag gttccgagca acgaagtctt
    12001 ctaatttatg gatttctgtt tgctgctttt cataagcctt ccattcactt gctaactgtt
    12061 ctgctttcaa atctagatat ttcgaatagt tacctttgta atggcgcatt tttcttctgc
    12121 ttaattcata gacttcattg actactttat ctaaaaaata acggtcatgg gaaacaatca
    12181 ataatgcacc agtatagctt tgcagataat tctcaagcca ggaaagtgtc tcgatatcta
    12241 aatggttcgt tggttcatct agaatcaaaa tgtcagggtg ttgcaaaagc atgcgagcta
    12301 aagctaaacg tgtgcgctgt ccgcctgata aagtatcgat tttctgatca taaaatgaag
    12361 aatcgaattt aaacccatgc aatacggaac gaatttcatt ttcataacca tagccgtttc
    12421 gatctgaaaa atcgtgttgc agccggtcgt attcttttaa ataagaacta taagcaggtg
    12481 tgtctggcgt accttcgcta atgaaaatct ctagctcgcg catccgctct tccatttgtc
    12541 taacttgttc aaaagctttc agcatctcgt tccaaactgt ttcattggaa tcaagtcctg
    12601 tgtcctgagc gaggtatccg agagtcgctg ttttattttt agcgatcttt ccttcatcag
    12661 gtgcttcaat tccagcaatg atctttaata aagtcgattt tccagcgcca tttctgccaa
    12721 ctaaagcgac acgagcgcct gtactgattt ctaaatgtat gttttcaaat aagacttctg
    12781 caccaaaatg gcgagcaatc tgattggctt gtaataatat catggaatcc tcttttctac
    12841 tttgtgaatt ctcctcaaat aaaaaactat ttttcaatta gtagtctacc ataaattcca
    12901 ttatactgcg agatttgcag aaatgataaa taaatgaata aagaataaaa tttcacaata
    12961 tctgagcaat ggaattgatt ttttcctata aatactgcta tgatggagaa atcaaagatg
    13021 taattagaca atacgtggag gtcatttcgt gaaagatcat attattccaa aggcgacagc
    13081 taaaagactg cctttgtatt atcgctattt aaggatttta aataatgctg gaaagaaaaa
    13141 agtgtcttca actgaattaa gtgaagccgt tcaagtagat agtgcaacga tccgtcgaga
    13201 tttttcttat tttggcgaat taggaaaacg tgggtatggt tatgatgtag aagatcttat
    13261 gcactttttt gcaaagacat taaacgacga tcaattgaca aatgttgcgc tgatcggtgt
    13321 agggaacttg ggaagtgctt tactaaaata caaattccat caaagtaata gcatacgtat
    13381 cagttgtgct tttgatgtga atgaggaaat cgttgggcgc atcgtagacg gtatccccgt
    13441 ttatccaatg gaagatatgt cagaacaaat caagatccaa caaatcgaag tagcaatttt
    13501 aacgataccc gctgaaagag cacaagaagt agtcaatcag ttaacggaag caggaatcaa
    13561 aggaatcttg aactttaccg ctgctcgatt gaatgctccg tcagatgtat tgatccaaaa
    13621 tgttgatttg acgaatgaat tgcaaacctt gatctatttc ttgcattctg acgcaaatgc
    13681 gcattccgaa aatacagcag aataaaaata aaaagcgatt gaacaaatga aggcaaaact
    13741 ttcacttgtt caatcgcttt tttctgtttg gacaacgatt attttgttcg gaagatttct
    13801 tcataagaaa gggaatcatc ttctgctgtc agttcatcta gtagataacg gattttttta
    13861 aagtcgatga accgtgcttg ccgaaagact tcttttcctt gatgaaaaat caggacaact
    13921 ggcgcagtca gcacttcaaa tttactagct acttctggtg tttcaaatgc atccaaatga
    13981 agtgccggaa tatcataatg tgtgagaagt tcctctagtc gtggacgaac agcgtgacaa
    14041 acactgcaat taggcatcga aagataaatg acggcaacgg atgactgttg cagtatgtct
    14101 tgaacttcag tcaagttagt ggtttgtttc atttttattc tcccttttat gatagaagtg
    14161 atatgtatga gaccttaatt taatgggaat aacagaaaaa gtcaattgaa gtgctttggt
    14221 aaaaaataag agttgtgtaa aaatttacag agcaacttgt tttttttgaa taaaagcgta
    14281 tatttgcaaa gcgaatgaac tagaaataaa aaggaggaaa ctcatgtttt cttttattcc
    14341 aaattcggtt ttgcagatga gtacgatttt cttatcgatc gttattgaag cattaccttt
    14401 cgtattatta ggctgtctta tctcaggcgc cttacaagta tttttgaccc cagaacgtgt
    14461 gaagagatgg cttcctgaaa atcgtatctt ctctattttt actggttcga tcttaggatt
    14521 tttctttcct tcatgtgaat gcggcatcgt accgatcgtt catcaatttg ttaaaaaagg
    14581 cgtaccagtt cacacagcgt ttgcttttat gctgactgct ccgatcatca atccaatcgt
    14641 gattttttcc acttttatcg catttggcaa ttcttggcag atggcaagct ggcgggtgat
    14701 aggcagcttt tttgttgccc ttgtgattgg tgtctggctt gcctattttc aaaaagacgc
    14761 tgtattgaaa gaaaaaatca cgtctaaagt agcagaaaat caccatcatc atgtccatga
    14821 agaagaacaa agtgagaaga atgaaccaaa aaatcagctg atccatcaaa ctgggcatgt
    14881 gttgacacat tcaatcgacg aattttttga tacaggtcgt tatttgatca ttggcggatt
    14941 aatcgcagct gcgatgcaga cttatttacc aactagaatt atgctaacgc tcggctcaac
    15001 aaagatttta gccattatca tcatgctgtt attggccttt acgatgtctc tttgctcaga
    15061 agcagatgcg tttataggat cttctttgtt aagtctgttc ggcacagcac ctgtagctgc
    15121 ctttttggtc tttggcccaa tggtcgatat caaaaatcta ctgatgatga aacgatattt
    15181 tacaggacgc tttattttat cgctgatcgg actgattgcc cttagcgtta ttggattcac
    15241 attatttatt taggagggaa aatatgctgc ggtttttgat tttatctggg tatttcgaat
    15301 tgatgatgta cttgcaagtt tctggcaaac tcgatcaata tatcaatgtc cattatcgct
    15361 acttagctat tctttcaatg attttatctg ctcttttggc tttagttcag ctgtatttgt
    15421 gggtcaaaaa cggaaaagca gaagaaaagg cacacgagca cgatcatgac catgggttgt
    15481 caaaacctta tcaacgtgga atcgcttatg tactgctagc tttgccagta atcgtgggga
    15541 cgttgtttcc aacagttagt ctcgacacta cgatcgtaga agccaaagga tttaatttcc
    15601 cagtaagtaa agaatcagta ggggatccgg agatgcagac acaatactta aagccggata
    15661 ccagtattta tttcaacaaa tcagactact tagaccaaat gaatgagttg aaagaaaagt
    15721 atggggataa gcaaactatc aagatcacag atgaaaacta tttagaagtt atggagctaa
    15781 tttataatta ccctagcgaa ttcattggca aaaaaatcag ctatgaagga tttgtttacc
    15841 aaacaccgaa cgatagcaat acagatatct tcttgttccg attcggcatt atccattgtg
    15901 tggcagattc aggagtcttt ggtttgttga cgcatatgcc ggaaggagta acggttaaaa
    15961 atgatgaatg gtataaaata gaaggaacca tccaatcaga ctattatcaa ccattcaagc
    16021 gtgaaatccc atctgtagtt gttacaaacg ctgagaaagt ctctgctccg aaaaatcagt
    16081 atgtgtatcg ttctttttaa aagaacaaaa taaataaaca tagctcagac agctgacacg
    16141 caaggacgtc ggttgtctgg ctttttttgc atgatgtatt catttgtttg atatttattt
    16201 tagaagcagc atcctgaaag tatttgatat cggtttcaaa ggtgttggaa aagattgtga
    16261 agagaattac aatttattcc taacatgtat gttgaaaagt tgtatgaaat gattttgata
    16321 gtaaaatatc gagtggaggt actttttatg gtaacgcgta tatttatttt ggatgatagt
    16381 ttggtttttg aaaaaatgct agtagaaatt ttggaagaat ccagaatttt attaagtcct
    16441 tggaaatttg agatcgttca gggattgaac gttatacaat ttgttgaatt cattaaaaat
    16501 aatgaaatct attcctcaga tatttttttc ctagacatcg atttgaacgc ctattatagc
    16561 ggtatcgaac taggcgaaat gcttagagaa aagaatgaaa agtgtaaaat tgtttatcta
    16621 acgtctcatc cgaataaagc aataactgtt attaatcgaa agattacgcc tagtggttat
    16681 ttgataaaag aattcactta tgaaaaaaat aaaaaaagca tccaaagtta cttattgaaa
    16741 gaaaaagaaa actatcctgt tcaacatgct acgaaaaaaa ggtggacaac tgtccgttat
    16801 ggtaatagcg atcactatat ccattacgat gaaatccttt atctaatgag catgccaggt
    16861 tataaaaata aaataggcct agtattgaaa gatgaagaga ttctcgtaaa cggcacaatt
    16921 aaaaaatata aaaaatcact cgaatatgag tatttatgta aagatttaaa agcttatatc
    16981 attaatactg aaaacattac atctattagc agagtaaacg aaatagtaac atttgcaaat
    17041 ggagaacaac tagagatggg aaagagaagt attgataaac taaagaattt tatgcaagaa
    17101 aagatagaaa atgaatcatt ttaaagaaaa caaagactca tatcttacct gttagaagag
    17161 tgttttcctg tagaagagaa caacccaagt agcagcctag tcgtttctat ccttttttgt
    17221 tatgcactct ttttgacatt tactccacca ataacgaagg gtacaataaa aagtaataac
    17281 aaacaaaagg agtacagaaa tgattgaatt catcaatgta agtaaaagtt acgggaaaaa
    17341 acaagcatta aaagacttgt ctctctcgat aagacaaggg gaaatttttg gatttttagg
    17401 acataatggt gccggaaaat caactacgat taaaagttta gttagtatta ttgaaccatc
    17461 atcgggaacg attttagtag atggaatgaa attgacggaa aatcgattga gtatcaaaca
    17521 aaaaatcggt tatgtgcctg attccccaga tattttttta caattgacgg ctggagaata
    17581 ttgggacttg atttcagctg cctatgaatt agacacacaa aaaaaagaaa agcgtttagc
    17641 agaattgaca gcgctttttg atatgtatag tcatcaaaat gaaacaatcg caagtttttc
    17701 acatggaatg cgtcaaaaaa cgattttgat cggcacgttg ctgccagatc cagatatttg
    17761 ggtattggat gaacctttgc aaggacttga tcctcaagca gcatttgatt tgaaagaaat
    17821 gatgaaggct catgccgcaa aaggaaaaac agtcattttt tctacacatg tattggatac
    17881 cgcacaacag ttatgcgata aactggctat tttgaagaaa ggtgaattga tttatcaggg
    17941 ggcagttagt gaattattga atggctcacc tgatgaaacg ctagaaaaga tttatttgaa
    18001 aatggctgga aggcaagcga caggagatgg accgtatgta taagcgacaa ttattagaat
    18061 taattcgagt taatctttta tatgttaatc cacagctcac gaataaagca agagagaaag
    18121 gaaaaaaggg aaagcgatta actatctatc ttttgtctca aaatcttttt tcagggctga
    18181 tttttttact gatttacgga tttgctatgt ttgctatgaa ctttgttaaa ttgccaggtt
    18241 tctttactta ttacgtggca ctttttggta tgttaggttt aactcaaagt atatcagtca
    18301 tttataatat cttttttgaa ggaaatgacc tgcaagtatt tttgcctctg ccttttggac
    18361 aagaacaggt tttttcagca aagattttgg tagttgcttt gaccatcatt ccttttgttt
    18421 ttccgcttct agtcatgttt attttaaccg gatggcgagc tgatctaggg attttgctta
    18481 ctatcattat ctcaatcctt ttgttttctc tatttttgat tattcttttt tgtctggcta
    18541 gtttgattgt ttttggtttg gctcgaacag cagtgtttaa aaaacataga aaaacagttt
    18601 ctagtatctt gcttggcagc tcgatgctga tcgcatttgc tggaatcatg tggatgaatc
    18661 atcaaacggg gactattgaa aatgagttaa cagatcggca tccgatttcg atattattgc
    18721 cattctatga tgctgccagt cagccacttt ctcaacaagg tttattgggt tggggaatac
    18781 tagctatcac ggctctggga tttttccttg ctgtaaaaca gctgatagta ccaaagctta
    18841 cagagcaact gactgattca aacagtgagt tcaaaataaa aagaacccat aaaaagaacc
    18901 aaaatgtgca tcagctttta tttagttaca atgctcaatt agtaaaagaa cctaatttga
    18961 ttatgcaagt tctttcttct tccttgttaa ctccaatcat ttttattctt gcttttgccc
    19021 taggaggcga aataaaatta actgatttag ataataagtt aatcggtgtt gttttcctgg
    19081 tagggatcgc attggctttc ttaacagtta atcagacttc ttttatcagc aatcttattt
    19141 ctttggatca agaaaatttt ctgtttatcc gttctttgcc aatctctatg aaccaatatt
    19201 taaaagaaaa gttcagattc ggatggatat tgcagagttt tttaactggt gggatcgcat
    19261 tattaagcgg actgtctttt cagctgcctt tgttttttat ccctagcttg ctatttggtt
    19321 ctttattcgg ctgctactta ttgtcactac gttatttcgc tagagattat cggttgctgc
    19381 tgctgaactg gaccaatatt aaccaattat ttaacagagg ttcaggaagt ttgggtttag
    19441 tcgcaactat gatgggttca ttgatcatca gtattattct tatcgtctta tacggaatgt
    19501 tggctttgtt ttatccattt tggttagtga atattcctgt gatcggttta gttctaatac
    19561 tttccgctct atggatcgtt tattatcaac gaacgttttg gaaaaaattt gaataaagaa
    19621 gaggggccgt gacaaaaatc atgtcgcagc ccctttttta cagatagagg gtgttcaaaa
    19681 gtcagtttct cagtattaag tcaattttat gtaaaaatgt gagaagctat ttttacaaaa
    19741 ctttttttaa tactcataat tacttcttat tgctcctgcg gttacttgtc gcaatgtttg
    19801 tgagatattt tgtcatcgct caaggctgaa cgtctctttc acaacctttt ctttgttaca
    19861 cttcgtttat ttaaaaagcc gtttttttcg tttcatcatg attgcgtcac gctttacttt
    19921 gaaattacgg atgttatggt taaagacttc tgataataca agacctaaag cgattgctcc
    19981 agcaatcata attgcttgga ccgcataatg agccgcttct cgataggatt cagtaacgag
    20041 atttcgaacc gcttgataag ctaaaccacc agggactaga ggaaccatcc cgggaatatt
    20101 gaaaatcgtt acgggcattt tcaaacgttt agagaaaaga tcgctgatga atgctactcc
    20161 taaagaacca agcaatgaac caaaagcagc agatccgcct atttgaacac agatccagta
    20221 gatcatccag ccaaaagcac cagaaagacc acaacaaatc aatgaacgcc taggtacatt
    20281 tgtaataacg gcaaatgccg cagtcgctaa aaaactaaaa gaaaactgaa taaatatcgt
    20341 ccccatactt gtgttccttt cctaataaaa aagctggaaa ataaaagcaa tcgcaaaacc
    20401 gatcatcgta gcagtcatca tcgcttctgt tccgcgagaa actcctgaga cataatgtcc
    20461 agctagcaaa tcacggatag cgttcgtaat ttgaactcca ggaactaaag gcatcacaca
    20521 tccgataatg attagatcct gattgcttcc taagccaaaa cgtacgctgt agatagcggc
    20581 tatgccaatc aataaagaag ataaaaattc cgataaaaat ttgattctaa aaaatttcaa
    20641 actatataga taagctgcgt atcccaatcc tccaatgact aaagtcacag gtaaatcggt
    20701 catctttccg ccaaataaca ccataattgt tccactgatc actgccgcgc taacgatttg
    20761 caaccagaca ggaaagaaag aacggtctcg gtcgattgct tgcagttcgc agtaaagttc
    20821 ttctaatgtt agctctgaag caacatattt acgtgaaaga tcatttactt ttactacttt
    20881 ttctaaatta atcgaacggt tggtaatttg ttccattcgg atggtcgagg tacgatcaag
    20941 accaataaag agaccggttt gagtgacata gctgaccaaa cggaaatttc cagaagctaa
    21001 agcaattcga ctcatcgtat cttctacccg atacatctcc gcattgcttt ccatcatgat
    21061 tttcccagcg agtaaacaag tgtccagcaa cagatctaat tcttttcccg tcatagcatc
    21121 ttctccaata attgattgat tagttttatt ttactacaaa acataccaga agcgtaaaga
    21181 ataaaaaaac ttgaggaagg aataaaagag gcgtatactg tttttgtatt gcgggtgtag
    21241 tttagtggta aaatcccagc ttcccaagct gatgtcgcgg gttcgattcc cgtcacccgc
    21301 ttaaaatagg ttgtgaaaaa gctgctctgc aacaagtaat aagaacagcc aagcaaaaac
    21361 aacttcttat gtttttaact tggatggact tattaccgca gatgcaagct tttgcgcacc
    21421 gtttaccaag cggttgtgaa atcagtgtat tgtcttgagt atgaagaaaa tttttgaata
    21481 ataataaata ccttacagat agagtggtga ctgattagag acgaggaatc cgtctctttt
    21541 ttgtattttt aagccatctt aaaacaggtt ttattttttg ctgtttctat ttctttctag
    21601 tatttattta taggggaaca tatgttaaga tttagggagc tgttagtaaa ggagtaaaga
    21661 aatgagcaaa aaaacaacca aggcgatcgt ggggatcgtc gctgctgtga ttgcaggggc
    21721 attcggtgtt tccaccacac aaaaagattc agatatcttt cagcagatta caactatttt
    21781 tgattccaca ccacaagctt ctcaagtagc ggatgtgcca gaatatgatg gaaaacatca
    21841 agaaatagaa atcaatggga atcagccgga atttacaaaa gaggatctta gcctttccaa
    21901 aggaacatgg gaaagctatt caaatattga taaattgaac agagtaggac aagccaatgc
    21961 tatgcttgga aaagatttgt tccctactga aaagagagag cctttgtata ttgacccgac
    22021 aggttggaaa caaaagaaat taagtgacgg gcaatggtta tataatcgca gccatttaat
    22081 tggtttccag ctgactggtc aaaataacaa cattaaaaac ttgatgacag ggacacgttc
    22141 gttgaatgct ccatacatgc ttgctcacga aaatgatatt gcggcatata tcaaagaaac
    22201 aaatcatcat gtacgctacc gtgtcactcc tcattttgag gggaatgaac tggtagccag
    22261 gggagtgcaa ttggaagcag aaagcattga agacaaaaaa attgaattca atgtctttat
    22321 ctacaatgtt caagatggct acacgatcaa ttatgagaca ggacaagcaa caaaaacaaa
    22381 aaattagtag cagctattcg aattttttat gaatattatg aaaaaattgt gtaaaaacat
    22441 acattcaaag aaatatagcg tatactttat gaaaagagta cttttgataa agctacagaa
    22501 aaaaggaaaa aaacatacaa atagtgtttc ttaatttatt cggaagtttg gaatatttgt
    22561 ttgtagtttt ccctttcttc gagtaaaata aggttgtaga aggtaagctg gaattacctt
    22621 gcgggaaaga ggtgtagaat catgggtttt acagatgaaa ccgtacgttt tggttttgac
    22681 gatagtcgca aaaaagaagt gagcgaaaca ttagcgattg tttatcgggc tttggaagaa
    22741 aaaggctaca atccaatcaa tcagattgtc ggctacttgc tttctggaga cccggcctac
    22801 attcctcgtt atcgtgatgc tcgaaatttg attcgccgtc acgaacgcga tgagatcatg
    22861 gaagtaattg tcaaggacta cctctcaaat catggagtga atttatgaga gtaatgggct
    22921 tggatgtcgg ttctaagaca gtaggtgttg ctatcagtga cccctttggc tggacagctc
    22981 aaggagtaga gatcattcgg atcaatgaag cagaagaaga gtttggcttt gatcggttga
    23041 aggaattagt agcacaatat gaagtagacc ggtttgtagt tggattacct aaaaatatga
    23101 acaattccat cggaccaagg gcagaagctt ccatgtcata cggagaaaag atcaaagaac
    23161 tattctcctt gccagttgat tatcaagatg aacgattaac cactgttcag gcagaacgta
    23221 tgctagtaga gcaggcaaat acttcaagag ccaaacgaaa aaaagtcatc gataaattag
    23281 cagctgtgat gatcttacaa aattatttag acggctcagg taagcaatta ttttaataat
    23341 aaaagaaaag aggtaatctt atgacagaac ataaccattc ccacgaccat gaaggacacg
    23401 aacacatcac attggtggat gaccaaggaa atgaaacatt atatgaaatc ctactaacag
    23461 ttgacggaca agaagaattt ggacgtaact atgttctttt atatcctgct ggtgtttcag
    23521 aagatgaaga tgtagaatta caagcttatg catacatcga aaacgaagat ggaacagaag
    23581 gcgagttaga acaaatcgaa acagacgcag aatgggacat gattgaagaa gtattcaata
    23641 cattcatggc ggaagaagaa gaatagacta taaagctagg agaaaccttg atatgatagg
    23701 gtttctcctt tttttatttt ttactgtatg ccatattgta tgccatctag tcaatattta
    23761 agtgttgtac taatttttca acagtctttt ctttcgtttc ttttgccaag tgaccgtaac
    23821 aatcgatcgt ctgactaatt tttgtatgcc gtaatctagt ttgaacttct accatagtag
    23881 ctccagcgtc caagagcatt gaagcatgag tgtgtcttgc tacatgcaca ccgagaaatg
    23941 gaaccatagc tttttcacaa atagtaatca atcttgcata aatagcgtgg tgtgtgatta
    24001 gttctttata gataccacaa aaaatcatag tcggatcagt tacaccaagt gtcagcatat
    24061 atttccgctg attaatctgc cattttttta atatagaaat tgttctttca tctagtggaa
    24121 gaaccccagc actacaatca gttttaggat cactgatttt atagccattt ttggattggc
    24181 ttagtgtttt attgatggtg accgtatttt cttgaaaatc aatgtctgac caattcaatg
    24241 caagggcttc actgatccta accccgctat aaaagagaaa gcgtagtaac gttttatcaa
    24301 agtcgtttcg ataagtttca ggtttgctgt ttaggtaatc aaacaaggtg atcagttgtt
    24361 ctttactgta aactttgacc ttttctttat gcttagtggt ggttctttta ggcattaata
    24421 cgttgtctag tggattagtc tcaataatcc caagattgat agcgtagcta aaaatacgct
    24481 tagaagttga atgaagtacc ttgtattggt cagtagtttc agcccagcta tttacaattt
    24541 gttgggcttt ttttaccgtg acttcattca cacgaagatt tccatatttt ggaagaatcc
    24601 actttctaaa cttgatttca gttttcatga aggtggcttc tcggacagtg gttttatatg
    24661 tttctagcca caagtcataa acttctttaa acgtttcgtt gttcgctttt ttaataccgt
    24721 ttttatcgta gtccacttgc aagcgtgaca aggcaagctg ggcttctttt tttgttttgt
    24781 aacctcgtct acgaacctta tcaggtttgc cagtcatttt gttcattcca agataggctt
    24841 catagagcca aaatttacct tttttagttt catattgctt gaatgttgcc ataatagttt
    24901 tccctccata gtgtagcaag ccgtgggggc ggttggagga ggcagtttat tattattttg
    24961 aatagtgttt atttagctca gtaacaagag ctgtgaactc ttttagaaga tcattttcat
    25021 aaaattcttg atactctttt ttctcatctg tatttttttc tgaatcatta attaatgagt
    25081 catatcgtaa aagcgtattt agaagagctg cgagataagc aattggggta ctcccgtcag
    25141 gaaattcaat tcgagatcct gttttaagat attttattgc gtttgttaaa taaatcttct
    25201 gtgagacagt caggttatct tcttcgatgt tattgatagc attagaaaga ttagaatcaa
    25261 ttatagagtt atttttttca atagtttttt tcaattgctt ttcaagcaca tttcgcttaa
    25321 tttcgggcat catatgcata tctcttaatg tataagatcc gtttaataga taggtagtgg
    25381 atacatctaa tacctttgaa agttgtttaa gcctggtgtt attgggaaga ttatagccat
    25441 tttcccaatt actaacggca cctttactgg ccggtgggga taatttacct ccaagttgtt
    25501 ccattgagag tcccttttca attctagcca gtctaattct ttgtcctgtc tccactgctt
    25561 cggggtattt ttttctagcc acattttcac caccattcat atattttctc tactatatca
    25621 cgatttaaat atgtgtgaaa cataaaagtt caaaaaagta tgttaaaatt cttgcaaatg
    25681 aaaaggtatg atggtatatt gagtttataa gaggtataga aatgtattca agagcctctt
    25741 gcattttttt aaaatctttg tatagaaatg tatgctaacg aggggggata aatatggaat
    25801 taaaaattga caaactcacg cttgatgatc cagcttttaa aattattgac gatcgagttg
    25861 ttcaacaagt agagcaaact caaggaacgt tactttcatt attagaaaaa aagtaccagt
    25921 ttccaaaata tatgaacaag gcacaagctg ctaagtatat gaacgtttca tacaatacta
    25981 tgatgcagaa atatgttcct aacggtttaa agttgattat agttgatgga gtcgtaagaa
    26041 tttcacaaga tgaatgtgat cgctttatgg aagaatacca aaaataaacg caagccgtgg
    26101 gggcaaaggg attaatagga ggaaataata atggaatcga cacaaaataa agcaatcgaa
    26161 aaagtattat caacaattct tacagaagac acagcggcag aattagcaaa cttggaaggc
    26221 aaagcgctag aagaaacgtt tgaatgtttg tacgaacaaa tggactatca aaaattgcta
    26281 ccacaagaac caacggtaag cggagtattg cgtggcttga acgatttagt acaagcagag
    26341 tttaaagaac gactttctat tgaagagtat caagaaattt tgtatcagca agttgagttg
    26401 ttagcgagct tgctagggct tgaactggag gacgttgaat gaaaactgaa atttggaacg
    26461 gacacattat aagatttgtc gatattaatg atgaatggtg ggcagtggcg aaagatgttg
    26521 cggaagcgtt aggtcttaaa caggttacta gagccattca ctctttgcct aaagatgggg
    26581 ttactactag taaggtcatc gattcattgg gcagaacaca agatgtaaac atcatcaacg
    26641 aaaaaaaata tttaccgcat ggcattcaaa agccgtaaaa aagaagccga ggcatttcaa
    26701 gactggattt tcgacatcat caaagaacta cgccagtcca caggacttga aggctttcaa
    26761 gtattccgca tgctagacaa agaacaccaa aaagaagcaa tgactaaatt aagccacgct
    26821 attactgaac caaaaccagt agactacatt aaagcgaatg tgatagccaa taaagctgta
    26881 tcaactattt atggtcattc caaaatggta aaaaagaaag atatgactcc tgaaatgttg
    26941 gttgatcgtg aacctatttt agatgagaca gtagaattaa tgactgttaa agaaaaatat
    27001 gggttgcagt tttcagtgag tgagaaaatt tataatcgtt ctgctgaatt gcagacaact
    27061 taggagcatt aacatgatcg agaacaaaga aaaagcctta tccataacag tcttggcgga
    27121 caggataaag gcaacttaat tgggataaaa cccgatattc tttgttccga ttataccata
    27181 ttaaaaaatc ggagggaacc attatgaaac gaaacttaat tataggaagc attttaatcg
    27241 gcggaatttt cggcttatta ccattaattg caaaaatagc tatctttgca ggattagcgt
    27301 tatatctctt cactgcttat gacgagtacg actatcaatt aagaactgga gggcataagt
    27361 agatgtacaa aacaaaacta ttaaaccaac tcgatagcct tgaattagag gaaattaatc
    27421 aagggatcgc tgaactagaa aataatatcg ggaaaaccta ctttggaaat tcattcaatg
    27481 aaaaactaac agttttgtat gtactcaaaa aacatgcaga acacaaaata atttgtcgag
    27541 aaatcaacga gctaaaaaat cagattttaa ccgcatggtt aaacattact gatatgcaag
    27601 aagcaagggt gaaaacattt aatacatggg taaagtatca gaatcaatta aaaggtgctg
    27661 aatttgttcg ggatgggttg aaatacgaac ttgagcagtt gaagctcatg gaggtgtctg
    27721 aatgatttat accagtattt tgaaaaagga ggagaggttt attggcaaat aattatcaag
    27781 cagcaacgga attacaaaag tcgggatggt caatttatcc cttatctcct ggaactaaaa
    27841 ttccaataaa aggctctagt ggttggaatg atgcaactaa cgattctaat caaattaatg
    27901 aatggtggac ggaagatgca actagaaata ttgggttaat gcttgaagat catcaaatgg
    27961 tggtagttga cctagatcaa cattctgaaa cacgaaacgg cgttgagaat tataaaaaac
    28021 ttgcttcaat gtatgatcca tttccttcta cttatacgga aatcacacca ggtaaaggaa
    28081 tccatttctt ctttaaaatt cctgatggtg taattatcca acaagaaaca ggtgcatttg
    28141 ctgatatctt cgggcgtgat gataaaggta aaagtttaag cgggattgat attatcacta
    28201 aaggagttcc aatagcgcca actatgatta tttcaagaag tgttgggaga gcatatgaac
    28261 ctattgaaaa cgtatctcta aataatattg caccagctcc cgattggcta gtgaacctac
    28321 tgctaaaaaa accgcaagaa ataaagactc aataccgacc cgtagcaaaa acagggacag
    28381 caaaaaaatt agatatgatt gttcaaggcg ctggcgaagg tagtagaaac gatcatttaa
    28441 ctaagttatg cggttggtta ctatggcacg gtgtagataa tcaaacttta gcagaattga
    28501 tttatacagc aaatgcgtac aatgaaccac cgctaaaaga taaagaagtg aatcaaatta
    28561 ttcgatcgat gattaaaaaa gatttgaggg ggaaagctca tggctcataa gcataaatta
    28621 gatagtattt tagactttcc cgaagccagc gagcgtgaag acaatatcat tgaattgaaa
    28681 acctggatgt cacgattaag atgcaataaa gacgatcaga ttaaaagtaa cagtgttgtg
    28741 aatgcagaat tgattttaac caatgatagc aatttagctg gaacaattgc ttataacgaa
    28801 tttagcggat acattcacct attaaaagat tctccttgga tcaatcgtac cgctggagaa
    28861 tgggaagaca gttttgagga tgccttaacg gcatatattg aagaaaacta caatgtagtt
    28921 tttgatgaca acaaaataca caaagcagta gtaaatgtgg ctagaaagaa tgttttcaac
    28981 ccagtaaaag aacgtatcga aaaagttaaa tgggatcaac agcctagact ggaaacactg
    29041 tttattgacc ttttaggggt agacgacaac ctttacacac gagaagtaac aaaacgttgg
    29101 atagtcggat cagtcgcacg tatctataaa ccaggaataa agtttgagat cgttccagtt
    29161 ttggatggac cgcaagggat tggtaagagt accgttccag cattacttta cacggatgat
    29221 tttttcaccg attcattaga ttcgctaggt gaaaagaaag atgattatat gcagcttcaa
    29281 ggcaatgtaa ttattgaact tggagaatta tcttcaatga acaaaactaa aattgaacag
    29341 ataaaaaact tcatcagtgc caagatcgat aaaattagac ctccttatgg tcggaatgtc
    29401 atagcttggg caaggcaatg tgtatttatt ggaacgtcga atgatgggca gtatttgaaa
    29461 gatgatacag gaaaccgccg tttttatcct ttgccttgta agaataagcc aaagatgaat
    29521 ccgtttaaaa caaaggatga atattttctt caagtgttag ctgaagcaaa ggtgcttttt
    29581 gataaaggac aacgaatcta ttttagtccc gatgaagata aagaagtctt agaaattgca
    29641 aaagactatc aagaggatgc caagatggag aatccaatta aagaagcaat cactaaatat
    29701 ttggaaatgg aaatcccgta taaatgggaa gaagctccag cgtgggcgag acgttcttat
    29761 tatcagaact atcctgacag taaatgtaat gagaaaaatt tacagcattt ctataatgga
    29821 gctactatgc aacaagagtt ttatttagtt gatagcgtac tcaccgctga tattttggaa
    29881 gctgtttttg ataaacaagc aaaggattta ttgaatggtc gatcagatgc agaaactaaa
    29941 aagattgcct tgattattag cagtattcct ggttgggaac ggaagcaact gccaaaaaga
    30001 aataaacgac gaggatttta caataagtca aatgcctatg aaaataaaaa tcgagctgga
    30061 aagtacaaaa agtaacgggt agtaacgggt cagtaacacc tagcccgtta ctagtttacc
    30121 cttactgccc caagggatac agcaatttgg taacggggta acaccttatt tccttaaaac
    30181 ttttgaaata gttagctaat atgctgggga ataatgttac tggattttac ccgttacctg
    30241 ttaccaaaac gctagaaccc ttgtccccgt tgggattgag tggtaacggg tacctgttac
    30301 gtaggtgtta ccacgtgtta cgaatcaagg aggaaagtaa atgctcaata ttatttcaac
    30361 aaacaaagca ccgaactttc aatatacaga tgaaatggat cggtttctaa tgaacacgct
    30421 ggcatttagt gtgggattgg taacagaaga ttattccaca tttgatccag aagtattaaa
    30481 gataatggaa gaagaacctg attggctgca ggagtcagta gcgtggtgtc aatcgctagt
    30541 agtgggatca ttggtagata gtggcaacta tgatgataca ggtgagctaa tggatgaatt
    30601 taattgtctg cttaacctat atgatcgagc gagacaacga gagcttacat cgaatgagga
    30661 taatttgttt ttaaacatcc atgataagtt cttggctttg ctactaacag atgatgaatt
    30721 gataactaat ttattggagg tagaataatt atgcatatgg aaagtattag atacttcgat
    30781 ggtgagaaac acattgagta ttcaaacact caagaagatg tagactttat tagttttgag
    30841 gaagataaaa tcactaaagt taattttaaa gacggaacgt gcttgaagat agtttcgcct
    30901 tatattgaat acaaatcaaa atgggaacaa gatgattctg acgaacgaga tcgctttggt
    30961 tggtaatcta tggcagttaa aaaacaatgt aatcatgctg gatgtaaaac attgattgat
    31021 tataggcaga agtattgtgg gaagcataaa gcaaagcaaa cggcaattaa gcgtgaagaa
    31081 agaaagcaaa gcgaaggtaa atattttcaa ttctatcaaa gtagaacatg gcgaaaggct
    31141 tcatacttgt atcggttaaa tcatccagta tgtgaggatt gcctagaaga aggcttgata
    31201 aggaaagctg atgttgtaga tcacaaaatt gaactaaaag atgattggaa tagacggtta
    31261 gatgaaacta attttcgttc tttatgccat gcacaccata attccaagac agccaatgaa
    31321 agacaaagac gagaaaagag taccctttga gttaaggggg catagtgtga aacttactga
    31381 caatcgatgc ctactcattt tggtacaaat aaccgttgtg aaaaggcata agggtaatta
    31441 caaataacga ttacacttgt aatcacaagt gaaaaagtat ataatgaaag taggagattt
    31501 attgaaaaat acaattgtta ttactgataa aacagggaaa cagcgcacca ttgagttacc
    31561 tcattttggt caagtgacca ttcaaatgca gaacggaaaa atcatttata tagataaatt
    31621 agataaagaa aaattctgat cgaaaaacga aggaatgtga gcttaattgc ttacgttcct
    31681 ttttcttttg tctgaaagga ggacaacatg ggacacccta aaatattaca cgatacaaaa
    31741 ggcaatatat caagtgaaga aaaagcaatc cgtgtggacg ctagagaaga attgttcaag
    31801 cagcaaccat taataaatat cacgccccct gactggatgg cagcgagcgc tagaagtgaa
    31861 tggaatcgta tcgtaccaac attaaaaaaa gattatccat tgagtgaagc agattatggt
    31921 tcattggtag cctattgttt agcctttgct cgaatgaaaa cagccgaagc cgagataaga
    31981 aaatcaggta cgtttatcac atgcgaaaac ggagtaaaga aagccaatcc agcggttcgg
    32041 gttcaatcac aagctatgag tgatttgaaa aaacaagcca cctcactagg tatgacctta
    32101 gaatcacgat caaaactagc tttgaacaag gttaaaaatg atgaacccga agacccgttc
    32161 aaagagttga tgaattcatg aatgattaca ttgagaaagt cctatcaggt aagctgattg
    32221 cacccaagaa aattatccaa gcgtgtgagc gtcatataag cgatttggag cgttctaagt
    32281 cagatagctt cccttatgtg ttcgatgaag aacaagccac caaagcgatt aaattcattg
    32341 agttgctacc atctacggac ggtaaagcaa tcaagatgtt aggatttcaa aaattcattc
    32401 taggcagtct ttatggctgg cgtactaaag aagggaatta caggcgattc aatcgagcgt
    32461 ttaccagtat gagccgtaag aatgggaaaa cgtatatcgc aagtggcatg gctgccaatg
    32521 cgttgattat ggaacaagaa ccagcagaag caaggcaagt attgtttgta agtaacgctt
    32581 tgaaacaagc taaattgggc tatgatatgc tgtctaattc acttagaaac gtggtcaagt
    32641 ctagtaagtt tttaagacca caactgaaaa ttatgaactc taagattcag cacttgccct
    32701 ctaattcgtt cgctatggca ctggctagtg aaaccagcac gctagatggg tttgcaccaa
    32761 caaccgcaat tcttgacgag tggcacgaag caaaaactcg taaaacgtac aacgtcatta
    32821 agtcaggaat gacccaacaa aagaacggct tattgtgtgt tattagtacc gctgggcttg
    32881 atttaaacgt tcctatgtac gaggaatact tattgttaga tcgtgtgcta aaaggcgaag
    32941 aacaagccga caggtacttt atagcgatat gggaattgga cgatcccgaa gaaattcacg
    33001 atcaagagaa atggatcaaa gccaatccga tttttgaaag tgaagaaatc aaaaaagtaa
    33061 tgattccaac cattcaagat gatgtgaacc ttgctttgaa acaaaataac cttaattctg
    33121 tattggtgaa aaacttcaat ttatggagac aagcgagtga ggacagctat atgattgctg
    33181 aagactggca ggcaaccgaa gtagaaccac aagatattac aggcaagccc gtttatatcg
    33241 gagtggattt atctaaaaca gatgatttaa ctagcgtttc atggatcgta ccgctagata
    33301 acggcgaact ttattgtgat tcacatagct ttgtagccac caaatatggg cttcaagaca
    33361 aagaaaagcg cgacggtttg ccttatcgag aactagaaaa agctggtgag tgttccatta
    33421 ctcaattaga aagtggaatc gtggactatg accaagtatt tcagtttatt caagatttga
    33481 ttcaagaaaa tgatttggaa tgtatgggga tttgttatga cccgtataac gctaattcgc
    33541 ttatcagtaa agctgaaaaa gccaactacc caatgttaga agtaagacaa ggaacgatta
    33601 ctctaaacgt tccgacccga acttttagag aacaagttta tgaaggcaac gttattcaca
    33661 ataaaaatac gattctcacc catgcagtga acaacgctat tttaaaaacg gataacaacg
    33721 gcattcagat taataaatca aagaacagta acaaaattga tccaatagct gcattaatca
    33781 atgcctatgt gtttgcaatg gattacttca ccacaacgga aggagcgaaa gcagacaatg
    33841 aattttatac aagtgaagaa ttttctttct aattacattc ataccgttct tttacttctt
    33901 ggattggtgt gtgtgttggt tgctatcacc ttactaacaa atgtctacta tggcttgtta
    33961 gcgctgggca tagtgcttat tggggtagcg gtcatgctaa atacagaaca gaagggaggt
    34021 taaaagatgg cattttttaa agcgagacaa aatacaacgg gagatccttt cctacaacat
    34081 gtggtatcaa tccaatcgga tgattacacc accagcttta caagcgttcg tgcattaaga
    34141 aatagtgatg tgtttgcagc cgttcgaatt attgctagtg atattgcttc aagtccgatt
    34201 caattggtca aaaacaatat gccacaagct gataatgaac tggtgaagtt actaaacgag
    34261 aaacctaatt cagaaatgga tggttggcat ttaaagtttg ctttggcggt caatatgttg
    34321 ctaaacggta atagctttgc agagattaaa cgcaacggtg aaaaggtaga agaaattcac
    34381 ttattaccta actcaagtgt aacggttact caattagata atggtacgtt gtcttatcag
    34441 attggtgata aaaaaagacg tgtgaagtct agcgatattt tgcacttcaa atatttcacc
    34501 caagatggtt taacaggatt accaccactt tatgcgttac gtgatgaact gaaaattcaa
    34561 caagctggca accgcacatt gcacaatttc tttactcgtg gtgtcagtgg gtcaggtatt
    34621 ttgaaggttc ataagtcaga tttagacgga tcagcaaaga acgcaattcg tgaaaagttt
    34681 gaagaagcca acggttcaag tagtggagat aatgctctta gaacgatcat tcttgatgaa
    34741 acaatggact acaaaacatt agaaataaac accgatgttt tgaagcttat caattccaat
    34801 gattggaaca caaaacaaat tgccaaggcg tttggtgtac cgattgagcg tttaggcgtt
    34861 gaaaatgaac attctagcac cgttcaaagt aatctccagt atatccaaag tacgctgatt
    34921 cattacttta atgtgtttgt gagtgaatta gatacgaaac ttgaaaccaa tatccgcttt
    34981 aattccgatc agttactaga gactgatcct gaaacaaaag taaaaaatgt attggatcag
    35041 gtcaaagggt cacttctcac gattaatgag gggcggtcga aaatggggct accccccatg
    35101 gatggtggcg atcgtttact agcaagtttg aactttacgt atttagatac gttggagaaa
    35161 tatcaattaa aagaacagga aggagttaca ccagttgaat aatgaagaag aaaaggaaaa
    35221 acggctgaca gaagaagctg agctaacagc cgattctccc aaagtagaga aagaaaatga
    35281 aaaacaacca acagacggca aaactatttc aggctatgcg ttgaaattcg ggcaaccgtc
    35341 aaaagattta ggcggctttg tagaagtgat tacacccgaa gcattaaaag aggtggattt
    35401 atcaaatgtg ttcttattat atggacacga ttattcaaag ccactagcta gtgtcaaagc
    35461 aggtacgttg aaattgaatg tcgatgatac aggattacat tttgaagcag agctaaccga
    35521 cacgacctat tcaaatgatg tgtatgagaa tatctcaaaa ggggttgttg attctatgtc
    35581 ctttgggttc gtgcttggat tagattcatt cgacaaaaaa gaagatggca caattgaacg
    35641 atcaatagat aaaatcaaag cacttaatga aattagtgtc gtgaccgttc ccgcttatga
    35701 ttcatcaaat gtccaagtaa ataagcgttc ttacgaatcg tttatgagta acaaccaagc
    35761 aaaacaaaca aacaatagct tagaatccac ttctaaagca caaaaggaga gtaataacat
    35821 ggaaaaaact ttaatcgata acgaaaaaac agaattgcgt gggtatgaag aatatatccg
    35881 ttcacaaggc gaagtgcgtg atggagtcac tactgtaaat gcagcggcag ttgttcccga
    35941 agaagtaatc ggtgaagtct ttgatttgaa acgttcaaat tataacttag ctcaatatgc
    36001 aacagtaaaa acagtatcaa atggacaagg taaatatcca gtagcaacta accaacaagc
    36061 agtgttagca acaaaagctg aacttgctga aattggtgat attgacgctg aaatgtttac
    36121 ttcagttgat tataaagtag aaactcgtgc tggtaagatt gccttatcaa atgaggttgt
    36181 ggaagattca gcagtgaata ttgtacaaga ggtcaaagat cagttagcga aattggtaga
    36241 aaacactgac aataagcata tcatggattt attaaaaaca ttcactaaga aaacggctgc
    36301 tacgttggac gatttgaaac aactatacaa tgtggcatta gacccagcat taaataaaat
    36361 ggtaattcta aaccaaagcg gatattacca cctagataca ttgaaagatt cagatggacg
    36421 ttacatttta caacccgatg tgacagcacc tagtggtaaa tcattattcg gtatgccagt
    36481 agtattgatt gcagatacat tgtttgccaa tcctaaagct ggaacattcc ctatgattat
    36541 gggggatatt gcacaatcta tctttgttgc tcgtagaaat caagtaacga ctcaatggga
    36601 aaaattcgat tactactcac aaggacttgc agtgatcgtt cgcaacgatt ataagaaaat
    36661 tgatcaaaat gcttcagtgt atattgagtt tacgccagtt gtaacaccaa aagtatagaa
    36721 aaatattggg cggcggttta tcccactgcc tttttttcat taggagagat aaaatggtaa
    36781 ttttggatag cataaaaaaa agtatgcgga tcgatcacac tattgatgat gactttattc
    36841 aacaattgat tgatacagca ggcgaatata taaaaagtgc tattgatagt agcgcaacgg
    36901 ataaagatat ggataattat cagcaatttg atttggcggt gtcattactt actcaacatt
    36961 ggtatttgaa ccgtcaagaa gccagcagcg aacggatacc agtaacggta caagcattag
    37021 tacaacaaat gagaggtgct tattatgcca atcattaaga atgtaaatga attgactgag
    37081 agagtcaagt ttaaaaagac aaaacgggta aaagatgaag atgggcagat ggtggatagt
    37141 gaagaaactg tatttgaatg ttgggctaat gtgcgttcac aaatgctaaa agacgtgctt
    37201 gctagtgtag gtaccattct tgaaggaacg ttgacgttta ttattcgata cgatcaagat
    37261 tatgaactaa caaacgatat gaaagtagct tggaaaaaca agagttataa aattatttca
    37321 atcaatgaag gaacggcgtt taaagattat acaacgatca tagctaaaca gatttcttag
    37381 aatgattaca cttgtaaacg ttgtgggtat ttagtataat taaggtagta aatgaagggt
    37441 tagctgcctg aattttgcaa gacttagcta gtcgaaatct attgttggac tgaaaattgt
    37501 aggtgtggtt gcaaacatgc tggactaaga aagatgatag atgatgaacg ttcaatttta
    37561 atacaggcat gctaggactg attggatggt tttggcaagc tgattgtgta gaaatcaaag
    37621 aacacgtctg ttgtggacgt gttttttttg ttataattca aaagaggtga tttaatggac
    37681 aaagcagagt ttacaaattt ttattggaag tattatctac atttagaaaa tgagtttatt
    37741 aataccacag attttgtgat gctcgatgag aataatttca aaacattctc tattgaatat
    37801 caaaaactac tactagcgat tggttcggag tgtgagatta ttttcaaaga actttgcgga
    37861 tttgatagca gtagcaataa aagcataact gattttaaag ctgttattaa atctagcgaa
    37921 ttaatgtgtt tggataatgg tgttagggtt atgaattctt taacattgac ttcactaaaa
    37981 ccttttggag atgggtggcc tgaagataca ccagattggt ggaaaatata taacagagta
    38041 aaacatggtc gttcttcaaa ttataaggaa gcaaatttgg aaaatgtgtt gtatgcttta
    38101 gcaagtctat atttattaga ggaatatttg cataagaaag taatactaga aggtgaagta
    38161 gactttataa gtccagagtc aaatctattt acgttatctt gggaaagaaa acattcgtcg
    38221 atgcaaaaag tgacgtttga aaaagtggat tcaaattatg tagctccact cattgatttt
    38281 aaagaacaag aagaaattta aaaaccccca cggcttattg aagtttttgt atgccatatt
    38341 gtatgccatt tggtttaaat cgcttgaaaa atagtgatag ataactctaa ttcatttagt
    38401 cataaacgct gttttgataa cctttatagt tctttgatat gggtttctca ttcatggcgg
    38461 aagaagaaga atagaacaaa agaatgaatt aataagatat aaaaaaaggg attgtgacaa
    38521 acgtcttgtc acaatccctt tttccaaata aacgatgttc aatcagctgc ccctcggcat
    38581 tcgctcgaaa aacggcgaaa tatgaagaac tattttgcca tttgtttctc taataatcag
    38641 gtcaaaacgt tgacttcaca gtctcttcct taaacggtgt tctcctgcca actcctcggt
    38701 cacaagtcac aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact
    38761 cggagctgaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
    38821 cggtaataag ttcaaccaaa cgaaaattat gaggagctat ttttgtttgg ctgttcttat
    38881 tacttgatgc aggacagctt tttcacaacc tcttttcgtt tagcactaaa tttccttaaa
    38941 aagtagaaaa gctttcgaag cctcgtttgt ttcttttact gtataataaa agaaaagagt
    39001 aacaatcgct aaaagatata aacaagagaa aggaaataca agatgattgg tctgatttat
    39061 tttgtggtga tcgttctggc gaacacagtt ggcgctattt ccgggatggg tggaggcgtg
    39121 ttgatcaaac cgattcttga tcttatcggc gcccattctg ttgcagggat ttctttttac
    39181 tcaacagttg cggtattcac gatgtccatt gtttcgactg tgcgacaagt atcaagcggg
    39241 aaatcactga attggcagat tgtcggttgg gtatctagtg gagctgttgt tggaggagta
    39301 gtcggcaaca ttgtattcga agttttttta cagttatttg aaaacgagaa gcatgtgcag
    39361 ctgatccaaa tttttttgac ggtattgacc ttggtttttg cgttcttcta caccaagcat
    39421 catcagccaa aatttcattt gacgtcatgg acttggtacc ttatatgtgg gggggttctg
    39481 ggctttttag ctagtttttt aggtattggt ggtggaccag tcaatgtttc tttgttgatg
    39541 ctgatgtttg cattgccaat aaaagaagca acactatatt ctctatctac gattttcttt
    39601 tctcaactgg caaaattggt aacgattgct ttaacaagta gctttatgcg ctttgattta
    39661 tctatgttgt tttatgttat ccccgctgct gttattggag gtttgtgggg agcaagattt
    39721 agcagggttt tgtctccaaa aaaagtgacc tttatttttc aagtaattgt cctcgtggtt
    39781 cttttggtca attgttacaa tgcctttgtc atcttacaaa cattaggaga atctagacta
    39841 acgcaagtca aaatcactga aacatattgt tctaaatgaa aaaaagagta tactatgata
    39901 aaaaaattca ttttaaaaaa tcagaaattg gctggtgatt tggatgttac gggaaatgcg
    39961 tttagaagat gcagaagcac tacgtgaaat caatgcggat caattagggt atgatatacc
    40021 attaaccgtt acggtgagac aaatgaagaa actgctgaag gagccagaga aaaatttttt
    40081 cttggtttat gaagatccta cttctaaaaa agcagctggc tatgtacaag cggagtccta
    40141 tgaatcgatt tttagcgatc caatgttcaa tattatggca cttgctgtgt ctaaatatgc
    40201 tgaaaaaaga ggcatcggaa aggctttgat gactggcgta gaagaagaag cgaaaaaacg
    40261 aggaataacg acaataaggc ttaattctgc agaatacaga gtagaagcac accaatttta
    40321 tgaacacatc ggttatcatt ccgataaaat gcaaaaaaga tttttgaaaa tcctgtaaat
    40381 ctttatcaaa aaaatacccg atcaccaagc cgatacttga tgatcaggta tttttgtttt
    40441 tttgactaag aaagtaattg catcaagaaa ccagagatga tcaaaacgat ggcaccacca
    40501 agtcgattgc ccatttgagc aaaagcaata agttccatcc gattagctgc agataagacg
    40561 gctacatttc ctgttccgcc catcgagttg ttgcataagc cagcagtaat agttgattca
    40621 attggatata aaccaaacaa acgaccgaca aatcctgaaa caactgaaat cgcgataaca
    40681 cttgtcagac ataagacaac aaattgccat gtcaaagcag aagctaatac attcagattc
    40741 agcaacgcaa taccgatacc ggcaagaaca gctgctgtca agtttttgac aatcaagtta
    40801 ttgaacatga tagctgcatc ttcataatac tctggtaata ggttggcgat tttacagatg
    40861 acaacgataa taatcataaa tgcgtaagca tggactttag gaacaaaata gttaccaatt
    40921 tgtcctaaga tgaagaaagt caatgatacc atcaaaccaa cacctaactg tggaatggaa
    40981 ggtttcacag ttcgaggttt tccatcgcca agatcgcctt tttccattaa tttaccattg
    41041 ccgttgaatt ttggcattga ttgtccagca cgagcaacta atgctgcacc gatgatagct
    41101 aagacatttg tcattgctgt cgcaggaatc aggcgggaaa tgatagaaga agcatccgta
    41161 cctaaaacat ttgcataaat cgttgataaa ggaacggctc cggctccaac accaccagcc
    41221 atcgcaggta atgagatgta taaaacggaa tttgcaaaac catttccgat aagcatgccc
    41281 acgagtccta cggcaaaaaa ggagacgacc attgaaataa gtgcaacggg aataaaacga
    41341 acagaagctt tcatcaatag attacggttc ataccaagga tgctaccagt aatcaaggca
    41401 gcaatataaa agtcccaaaa gcccatattg ctgacaaagt tttctgtgga tttcactaca
    41461 tattcaggta agatcccaaa tgtagcaatc gcagcagaag cgaagatcgc aaaaacggaa
    41521 ccaccaccca aataactttt gacgataggg atttttgtcc cgataaaatg aaataaatta
    41581 ccgaaaataa ccaaaactgc gattggtcca atcatattcg tcggtaattt ccctaaagcc
    41641 attgcaatga tcaggacaag gaccatgatc aaataaagtg gcaaacttac gccggtgatt
    41701 tttgtggacc aaaaaccttc ttttttcttt tcctcaactg cagttgcagt tgttgttttt
    41761 tgtgccattt ttacagatcc tttcttattc tgtatcatat gaaaaaagcc aaagaaaagc
    41821 gacaaaagag caggagttgg ctggccgctg ttttgccgca gtcgcttttt tctttttaga
    41881 cgtcatacaa agtttctgta tgttctttta ctataacgat cttaatcttc taaagattta
    41941 tattcaggaa cccatttagc agattcaact gcttctttga tatccgtgat ttcttcacga
    42001 ttcaagtttt gtgcgacaac tgattttgcg acagtttcag caatcgtttg agaaaattca
    42061 gtgatttttg ctactggagg caagatagct gctcctggtt ttgttacatc aacgattccg
    42121 cctaatgctc gactagcttg agaaatgatt tcagcattta ctcgtgtagc tgttgaagca
    42181 atcaaaccaa gtcctaaacc tgggtacatc aaagcattat ttgcttgacc gatttggtaa
    42241 gttacaccat tatattcaac atcagcagca gggatacctg ttccaactaa tgcttttccg
    42301 tccgtccatt ctattaaatc ttttgctttt gcttctgcca attttgttgg attagacaaa
    42361 ggcatgatga tcggacgtgg tgtatgagca gccatttctt tcacgatttc ttcagtgaat
    42421 gctccaggtt gggtagaagt accaatcatg attgtcggat ggatcgcttt tacaactgct
    42481 tctaagtttg tcaattcatc agcattagtg aaatctgagc gtttgcgagc gaatgggatt
    42541 tgaccaggag tcaatccttc tgtatcttca aacaataaac cttgtttatc tacttgatag
    42601 aaatgttggc gtgcttcttc ttcaggtaca ccttgacgga tcatctcatc taaaaggatg
    42661 tttgcgatac ccacaccagc agtaccagca ccaaatgtca aaattatttg atctttcaat
    42721 tgttcaccgg atatattcaa tccgcctaat acacctgcta ggacaacaat tcctgtacct
    42781 tggatatcgt cgttgaaagt agtgatttga tcttcgtatt tttctaagat cgctgcagca
    42841 tttcctcgtc caaaatcttc ccaatgcaat aacaattctg ggaataattc ggtagctgat
    42901 tgaacgaatt gatcgatgaa ttcatagtaa gtttcgcctt ctacacgagc atgacgattg
    42961 cctaagtata agggattatt caataattct tcattattag taccagcgtc gatcgataca
    43021 ggcaaaactt gtgctggatt aataccagca gcagcagtat agaccatcaa tttgccgata
    43081 gcgatgtcaa caccgttcac accccagtcg cccataccta agattccttc tgcatcagtc
    43141 acaacaatca aacgaatgtc tcgtccatct gccgcgttct tcaaacttgc tttgatgttt
    43201 tctggttcgt cgattgaaag aaatgcagca tcttgcggtt tcaagaaaat ttcgttgtat
    43261 tgttcgattg aatccgcaac gacaggatca taaacgacag gcatgaattc aactaaatgt
    43321 tcgcccatca atttataaaa caatgtccga ttcgtattga atagattcat taagaagata
    43381 cgtttttcca aatctgtttg tttgcttaag tattgaccat aagcttgaac agattgttgt
    43441 tccagtgttt ggacagtact tggaagcata ccagtgattc catattttgc ccgttcttct
    43501 tttgtaaaag ctgttccttt atttagaaaa ggattattta ataagtttaa ccctgtaagc
    43561 atgaatgatt cctcctaagt tttaatacaa acgaagtata gaagtcagat gatgatatag
    43621 tcaaaaagag caggtatgat aaattttatt tatatgtaat atagccaaaa gaaatcaaaa
    43681 tagcagtatt tgttcttttt atatcgacaa tccttgcttg aatactatgc gtatctctta
    43741 tatgctagag aaagaaaagt agaagaataa gggatagatg gaatggataa ataggatttc
    43801 tgaggaaaaa agcacatgat agcgttgata ggagtcacct atgtcaggtg ataaaaatac
    43861 ataagtagaa aattaagagg aggaagagaa aatgaaagaa gttcaattga ttagaaaaag
    43921 cgaactatca gaaggcggtt gcaatgcatg tggcgtagta gaagcgacaa gctatacatt
    43981 aaaattagat tccaatcaag caataatctc tgaactgaca gtaggcggtc ttgtggacag
    44041 tctggcgctt gctgaaggtt ttactggaga agatatttat gagatgtttt cagaagtccg
    44101 tcagttaaaa aaaggagaaa aatgcataga ggttcatcat gagagcccga atgtgaggtt
    44161 caaacgtggt gataatgaga tgatcttcaa gaatcatgtg tctgatcaca ctgaactata
    44221 tgaaatcgtg aatcaaatac tgtctgggat ttttgaatta ggaccttatg agttcaagga
    44281 agaaaacggt aatccaaaat taaatgaaga atggcaagaa acgattgaaa cacaaagaaa
    44341 caatccacac ttatttcaat agtcttccac agtatttcgt aaaaatgttg atgaaaaaga
    44401 aacaccgtga atcagaggtc gtgaaaaacc tgccctgcat caagtaataa gaacagccaa
    44461 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagtttt
    44521 tgaacaccgt ttaaggaaga gactgtgaag tcaacgttct gacctgagta ttagagagac
    44581 aaatggcaaa atagttcctc atattttgcc attttttgag ctaataccga gggtcagctg
    44641 attgaacacc gttttatcga gaggttgtga aaaagtcgct tagtttcgag tagtaagaaa
    44701 aattttgtga aaatggcttt ccacattttt gcataaattt gacttaatac cgagaaaatg
    44761 gcttttgaac accgtttatt caaaaaaagg gactttgaca ctacttttgt caaagtccca
    44821 tcggtttttt atctattttt attacaatca tttcttccag agtagtgaca tctggaatgg
    44881 ctgaaatgta aacagattat ttgcctgtat caatgtcgaa gagtaatata aaaagtgtaa
    44941 acgctatcat attgttcatc attcaaattt tatagagaga aggcattgag atggaaaaaa
    45001 catatcaagc aggtacaaat gaaggaatag tagattttat caatatggaa gatttagaaa
    45061 tcgcggcttc acaagtgatt ccagctggtg gttatggtta catcagcagt ggtgctggcg
    45121 acttatttac ttatcaagaa aatgaacggg cattcaatca tcgtttgatt attcctcatg
    45181 tattaagaga tgtagaatta cccgatacaa ctacacattt tgacgaagaa atgctgactg
    45241 caccaatcat catggcacca gttgctgctc atggattagc tcatgtgaag gcggagaaag
    45301 cttctgcaaa aggtgtagca gattttggga cgatctatac agcaagttct tacgcttctt
    45361 gtactttaga agagataaga gaagcaggcg gggagaaagc accgcaatgg tttcaatttt
    45421 atatgagcaa agataatgga atcaatttgg atattcttga agtggccaag cgtaatggag
    45481 caaaagcaat cgtattgaca gcggatgcaa cagttggcgg aaaccgtgaa acagaccgca
    45541 gaaacgggtt taccttcccg ctgccaatgc cgatcgttca ggcttatcaa tcaggagtag
    45601 gccaaacgat ggatgctgta tataaatctt ccaaacaaaa acttagtcca aaagatgtag
    45661 aatttatcgc tgctcattct gatttgccag tctacgtgaa aggtgttcaa tcagaagaag
    45721 atgtctatcg atcattagaa tctggtgctg gtggaatttg ggtatctaac catggtggcc
    45781 gtcaattaga tggggggcct gctgcgtttg attcgttgca atatgtggca gaagcagtag
    45841 ataaacgtgt accaatcgtg tttgacagcg gtgtacgacg tggacaacat gttttcaaag
    45901 caatcgcatc aggtgccgat cttgttgcta ttggcagacc cgttatttat ggattgtctt
    45961 taggaggaag tacaggagtc catcaagtgt ttgatttctt taaaacagaa ttggaaatgg
    46021 tcatgcaatt agctggaaca caaacagtag aagatatcaa aaaaataaaa ttgcgtgaga
    46081 atcgttttat ttaagaaata aatgacgaaa aaaataggag tgcggcagat gatgccgtac
    46141 tcctattttt atagttcaag gatgtcacta atagaataat ttgaaacgaa aaaataaaat
    46201 tgaaatattt tttcatactt aataaaaaag gaagaatatt catgtaaacg attttattgt
    46261 ttttttctct tttatacaaa aagggtcata atttcaagta agcggatgaa ttcatgagga
    46321 ttttttgcat actgtctcta ctatacttag gtcactaaga aaaaggagtg atttattatg
    46381 aaaaagaaca tgattgggac attattactt tcaacacttc ttctaggcgg cttggcaaca
    46441 ccagcttttg ctgagggtca agcgacttca aaaggagata ttacctttac tgaaccaaca
    46501 aataccgttg agcctcttaa ccctactgat ccttcaaaac cagtagagcc agcagatccg
    46561 gaaaatccag caactggcca gacaggttct ttaacattgg atgtagttcc tgaattgcca
    46621 tttggtacac acgagattga aagcggaaca aaaacgtatc aagtagacgc ttcaaaaaac
    46681 gatacacctt atctccaagt atcagatcgt cgaggtgtag gtgcagatgg ccaagcacaa
    46741 gggtggaacg tgacagtttc ggtttcagat tttgtaaacg gttcacaagt tttgcaaggc
    46801 gctgaattag attttggaac atccactgtt aaaagtacgt cagataacga atccactgga
    46861 ccaactagtc aaactgtaac tgggttgagt aaagcaagtg cagcgacacc aatatttaca
    46921 gcagcaaaag atcaaggtct gggaacatgg ctttctgttt atgatccagc aaatatcaca
    46981 ctgaaagtgc cgaaagcagc agctggaaca ttcacggctg atttgacttg gaacctcgtg
    47041 gctggcccag tagcatagag tatgaaataa attcaacaaa ctgcggtgaa aatactatag
    47101 gtgaaggatt ttttaccgca gttgttgttg aaaggatgtg gtggacaatg aatcaaagta
    47161 aacgactgtt tgtttcgttt ttttctattt taagtctatt tttcattttt ccgtcaatca
    47221 gccaagcaaa ggattcagca ggagactttg gaatcaaacc ggtatttcca gagaaccaaa
    47281 tagataaagc aatcggttat tttgatttat tagtggcacc ggaacaaaat cagacactag
    47341 aagtaattat cagcaattct tcagatgaag aacgaacatt tgaggtctct gtcaatccgg
    47401 cggtaacgag tgatggtgga acgatcgatt atagtcaaaa aaacccaacg ttagatgaga
    47461 cattgccgtt tgatgtccgt gacgttttgc tcattgcgaa aaaggaaatc aatgtatcag
    47521 cacatgcaga aacaactata cctatagaag tgaaaatccc agcaaaaagc tttaagggac
    47581 gtgtattagc gggtattcat gtttcaccta aagaagaagc tgaaacagaa aatgctacag
    47641 aaggagcaca aatcaaaaat cgtattgctt ataatctcgc agtcgtttta caagaaagtc
    47701 aagagacgat agaaccggat ctgaaacttt tatcaggaga tttggacgag gtcaacgcaa
    47761 agccaactgt tcagcttcgt ttccaaaatc ctcagcctag gattatcagc aatttgatat
    47821 ttacgagcaa gatcttttat gaaaatcagc tttatattga aaatacgtct aatgaatttt
    47881 tagttgcacc aaattcgaat tttcacttga atcttgattt agctggtgat aaagcaaaag
    47941 ccggcgatta ccgcgcagaa atcatagcaa aatcaggcga cagtaatgaa tggcgattta
    48001 cacaaaactt tacgatcaaa aaagaaaaag cacaaaaagt aaatgaaaat tccgtttttg
    48061 cagtacaaga acaatctttc ccatggcttt atgcaggatt ggttgctgca gttctagtgt
    48121 tatggttgat tttgctgttt ttgtgggtcc acaagaaaaa gaaaaaagga gaaacaacat
    48181 gatgaggtga tttcgttgaa aacatcgatc ttattgggag ggattattgc aagtttgctg
    48241 ttcttcagct ggcaagagcc agtccaagca gataccaaaa gttcaggtac gattacattt
    48301 tatgatctaa gtccagttcc gcatccaagt ggttcagtca atggcgcatc aaaacagcag
    48361 acacagctac cgatttataa agaatctaat caacatggcg tattcccgga gacgaatgaa
    48421 gaaaagatcc gttttcttta tttgatcatt ggtatagaat tatggcttct tgcgtggttg
    48481 ttgttatgga gaagaaagga aaaggaggat gaacatgttg ctacaaaata aattttcatt
    48541 ttttcgctcc ttctttttta cttcgctttt tgttttaagt atatttatct tttcaccttc
    48601 ggcagaagct gttggagcaa cgcctcctgc catttcttat gatccataca cgtatgaaaa
    48661 tatcgtacct ccaaatggtg gacgtagtgc agtcaatggc gggaagcttg tccaactaac
    48721 tggggctaac caattgccta aattgactgc tacttatttg aacgatggtt caaatgatcc
    48781 ttggaaaggt ggcacggtcc gttttcattg ggaaagccat gtgaaactaa caaatgtact
    48841 tgatttggtg aatatcactg cacaaggatt tgcatttgtg gcgatcatca atttgccgga
    48901 acatgtatca agcagtgatg tattaaaagc aattgactgg aacaacgcct acttgtatat
    48961 tgccggtgcc cccatcaagg ttactagcgg tagtttatta tcagcaggaa gccatacctt
    49021 gcgttttggg atggggtcgt gggatacaaa tactctattg gcagatatta ttgctattat
    49081 tacgcgaggc gaattcaacg tggacgatat cccgcttcaa tttgatgtta cagctaatgt
    49141 cgcgaagatg acagaaaacg gagataaata tgatacgagt ccaaacaaaa ttttgaccaa
    49201 gggtaaatta caaccttcta tgtctaaaaa ggccgttttt tctgttgatt tttatgattc
    49261 gaataatatt atccaagatc gtatgttcaa ttcgatttta gctccagctg caggtagatt
    49321 ttatcctaaa ttaactggcg gaaacttgaa tccaggagca tatgcatttt ctgcaagtgc
    49381 agagataaat acgtggaata gttacatctc aacaagtgat tcaacaggaa aatataatac
    49441 atttgctgat accacagaat acgtggatgg aaataaccag aaccttccag gctctaccaa
    49501 tagtcggaca ttgacgatgg ggctgactga aggacgtttt gatcagttgc catttagtcg
    49561 ctttgatcgc gtagtcaact attttacagg aaaaaacgtt acacaaggag caatactgac
    49621 tcatactcca gcaagcacaa gtggattgaa tcagacagcc aatatcgtgt acagtgggaa
    49681 agatgcgcaa ggcggattgc tttctcctgt tgctttaaag gtattggagc agtacaagct
    49741 agacggaacg gttttaccaa caaacttaac agccgatagt cagtggggaa agctcctttc
    49801 ttctgcatcg taccaagtca cggccaattg gtcagcaact gaactaaaaa agggttcgat
    49861 ccattacagg ctttattcga aaggaaccca aaaattagcg acaggatgga cagatcaact
    49921 tttccaaacg atccaatcaa ataacggggg tgtaaataca gctacttcta cactacctgc
    49981 attggcttca gggcaatatt attttgatta tcgcttggtg gacgatgtac ttactaacat
    50041 gtatccgtct tttgcgtaca aatggcagtc tgaacaagct ggaatcacca ctcttcctca
    50101 aataacagtg gctaattttc catctgtgag tgcagatagt cagctaaaaa accttagcag
    50161 acaacctgag acaggagatc ccctgtctgc tctatcagga gatacgattc aagaaaatgt
    50221 gacattcacg ttaacaaaat ctggggatgc gataaccgac aaaaaaatca cgatctcact
    50281 tcctgaaaat actacttata tcaatggttc cttaaaatta aatggtacaa ctatcgcaga
    50341 taccggcatt caacaaggag tttctgtccc agcagatcta ttgagcaaaa taggagatac
    50401 cattcatctt acttacaact atcaattaaa tactgtagat acttctgtac aatccgtcag
    50461 catactgaca aaggcagctg tactttccag caatattaca ttagcagatg gtgctaagct
    50521 tcctaaccca gttgtccaaa catctgctaa aacaattctt gtccccaaac aagaattaac
    50581 attagttaat gtaccagatg attttacatt tggtaacgat ctccccaaac cgttgaagac
    50641 aagttattat gaagcaaaag gcgatttttc ttttgatgtg cgggatactc ggcttccaag
    50701 cacgtctcct tggcaactga cagggacatt gacttcttta tttaagaatg atcaaggtca
    50761 agaattaagc ggaacaaaat tatacttcaa tcattctgga tcaaaacaat tgattcagca
    50821 aggtcaaaac acgttgattt atgagagtga tggaacagct aaaggagagg ttctcgttga
    50881 ctttcccgat accgatggtt tactcttaga ggtaaatagc agtacgaatg ctcaacctgg
    50941 cgcaacgtat caaggcatgg tcacatggga actgacagct gggccaacca gctaagtgat
    51001 tagaatttgt atggatctgt gataactgtc acagatcctc tttttcaagg atgagaagga
    51061 aacttctgct gttaaaatca gaaatgcttg gaggagtgga cttggaactt ttcagtttgc
    51121 ttgaaaaaaa tgaacaacgg caaatcaaac ttttccaact tttattagag gaaaaaggag
    51181 agatttccgt taataacgta cttacccgct tatcagttga tcgggctacc ttgaaagaag
    51241 atctgtttta tttacaagct aacttggaaa atatcaaaca attggaaatt gttatccaag
    51301 aagggaatat tttattaatc agacatggaa atatagcagc agtcgatgtt tattatcatt
    51361 gctacttgcg ctattctaca aaatatcaga tacttcttta tctgttggaa aatggctcat
    51421 ttgatcggca gaaacttgtc atggaactta atatcagttc ggctactttg tctcgcagag
    51481 tgaaggaatt aaatgattct ttaaatgagt ttcatctgaa aataaaaagc gggcggctga
    51541 ccggtccaga aagtcaaatt tgttattttt atttccaatt attttggttt ggacgtcctt
    51601 atcttgaaaa caaaaaagaa tacagtgatt tatcaggaaa cactttttta gatctgctgc
    51661 aaaaagagtt tagttttact attacagaag aaggacgatt gaaatttgaa atatggcttt
    51721 ccattatgaa gaagcgaatg cgctgtacga aaaaatccaa accagattat agcaatcttc
    51781 ctgttggatt gtttcaaacg acacaatttt tattggacct ccatacattt ttgacccgtt
    51841 acttctttca atatgccttt ccttggaatc aaaatgaaac gttggttttt tatcttttca
    51901 tgatcagtaa ctttacatta gatacacata actcgcatgt ccaggagttt ttgataagcg
    51961 aaaaatacaa agacgacgta gtagctcaat tgaatcgaac gtttaaacaa tcgatagaag
    52021 aatatttctc tttttatgtt tttccagaag agatttcgca aaagattgcg ttgacagtga
    52081 tgcaaaatca cgctcatttt gcctatttta gaggatggat gaatattttt ggccaagaag
    52141 gattaaaaca gcggttaact gaagtagaag ataaacaatt cctggtttta tgtgaaagat
    52201 tggtcagaca aacatttgct attgttgatt ttactgaagt agacgaggaa aatgcccgct
    52261 ttgaattatt tgctcgctat gcatctattt tgcggacgct gatcaagcag ttagaattac
    52321 gtctgcaaat tgcttatgat cttccttatg aaaggctaat ggcggatatc gtgaaagaaa
    52381 tcatccagga acaattgctg aatacgatca aatatgattt agtcgaatac gagaaagaaa
    52441 agcagtatga tatcattttg actagccaat tgaaagagta cccgtcacag aagtccgcta
    52501 aagtttttgt attcactagc aacgaatata attatgattt cccctatttg aaccaatttt
    52561 taaaagaatg ttatttagaa aaattgaatt taaggatgaa taaaacatga aaatcgtgat
    52621 cattggtgct tcccatgcag gcatcacagc tgccctaaat ctaagaaaac ttcaaccgaa
    52681 agcagaagtt ttactgatcg atgaagatca taaagatgga ctaggctatg tttcaaatgg
    52741 aatcaacctt tatttaaaag gaaagatacg tagtttagct gaagttgccc ataacatgcg
    52801 gactcttcaa gaaagtgggg caaaactgat caccgaatgg agagtaactg aacttgatcc
    52861 agacaaacat cagctcatcc tcgcatccaa agaaggaaaa aacgagacca taacctatga
    52921 taaattaatc gtagcaacag gttcctctcc tgtcaccttg tataaacaaa ttgaagctga
    52981 aaatgtctac acctataaaa atctagtgca atctaagcaa gtacttgccg ctttaaaaga
    53041 agcaaaagaa gtagtgatct tcggtgctgg ttatattgga ttggaattag cagatgcttt
    53101 gagaaataaa ggatacatta ttcatctagt tgattatatg ccgaatgttt taacaagata
    53161 tttcgataag gatatgatca acagttttca aaatcagctg caaactaagc aaatcaattt
    53221 ttatccaaat gaattcttga tcgattggaa aaaatcagaa gagaaagtag tatccgtaca
    53281 acttctatct caagcaataa aggcagatat ggtcattttt tctgcccaaa ctcgtcctaa
    53341 tacgacattg ttaaaagaaa aagtggcttt gtatgaggat gagactgtga tagtcaatga
    53401 atatctgcag acaagtgatc cggacatcta tgcgattgga gatatcgtcc cagtcagttt
    53461 tgacaaaaat aaacggcatc tctttttacc tttagttact cgagctgtac atatggcaag
    53521 agcagtagcg ctaactttga gtggtcagcc aaccgcttac gacctcagac aaaagataac
    53581 agcagcagtc attatagact actttttagg aactgtaggg ctgacagaag atgaagcgcc
    53641 attcttggaa caaaataccg gttcgtgttc aggagaattt gatctatttc cacaatacga
    53701 tgaagaaaac aaaacagtaa atgcaaagct gatctaccat ccggatacat tagaaataat
    53761 tggcggacag ctgataagcc aagaattctt attatcagat ttgaacctgc ttgcggatat
    53821 cgtgaaacac aaaactacga ttccacagct agcagttgag gattttggat ttctgtctga
    53881 acacacctct cgttttcact acctcaatga gttagctttt aaagtactag ctaagagagc
    53941 aaatagcaat agagtagata aaagactgtg agaaatatca cggtctttta ttgtgtgggg
    54001 atataataaa tattaatcaa tcgagaataa aaaattcata taatgaaata gcggaagaat
    54061 tttttgagca taatattcgc caaaaattta tcaagtgata aaattgttgt ataaaatgat
    54121 tatttcagga ggaggagtta aatgttttta gcattaaatg aaattatgca ttcaaagtta
    54181 cgttatgcgt tagttgcagg ggtgatgttt ttgatcgcct acctggtatt ttttttgact
    54241 gggttagctt atggcttagc tcaagataat cgaacagcag tcgacaagtg ggaggcagat
    54301 tcgattgtgc tttcgaaaga tgcaaattca aatctaggga tgtccatgat tactaagaag
    54361 atagcagaag aagtcgaagg tgggaaagtg gcgtatcttg cccagacacc tggagtcgtg
    54421 actagtaaag acagtacaga agaaggaaaa atcaatgtta gcttcttcgg tatcgataaa
    54481 aatcaattca tcatgcccaa tcttgttgaa ggaaaagctt ttgataacga tgatgaggca
    54541 gtaggcgata ttagtttgaa agaagaatat ggtctagccg taggagatac agttaagtta
    54601 tctggtagtg acaagacgtt taaactaact ggctttacgg atcatgccaa attcaatgtc
    54661 tcaccagttc tctatacaac catcaatgct taccaagaga tccgcttcga aaaagaagat
    54721 acaagtgaaa atgcacggat taacgcaata gttgtcagag gtaaaatcag taatttacct
    54781 gaagatttag aacagatcaa aatttctaaa ttcatcaatg aattacctgg atataatgcg
    54841 caagtattga cttttggatt tatgatcgga tttttgatcg ttattgcggc tattgtgatc
    54901 gggattttca tttatgtact gacgatgcaa aagattaata tctttggtgt aatgaaagca
    54961 caagggatca caggaggatt tattgcgcgt tctgtagtgg cacaaacatt cattttatca
    55021 tttgttggta ttcttcttgg tctattagga acagtgggaa catcccttgt tctacctgat
    55081 gcggttccat tccaaagcaa ttggctgttt tttggcgtca ttagcttgtt gatgctggta
    55141 gtagctgtgt taggcgcact attttctgtt cggacaatcg taaaaatcga tccgttgaag
    55201 gcaattggat aagaaggagg aagagcatga aagcaataga atttaaagaa gtagaaaaaa
    55261 gtttccaaga tggcgaccaa gtagttaaag cattgaaaga aacaaccatg agtatcgata
    55321 aaggggaatt tgttgcaatc atcggtcctt ctggttcagg taaaagtact tttttgactt
    55381 tggcaggcgg attgcagacg cctagcagtg gctctgtatt tatcaatgat caagaattca
    55441 gtaatcaaaa agaaagtgaa cgcgttaaac tacgttttaa agaaattggc tttattttgc
    55501 aagcttccaa tctggttcct tttctgacag taaaaaagca gttattatta gtagataaga
    55561 tcaaacatga acatcgtcaa aaagaagcaa aagaattatt tgagcagctt ggcgtggata
    55621 agttgatcaa caagtatcca gaagaactat ctggtggaga acggcaaagg gtcgcaatcg
    55681 ctcgtgcatt gtacaatgat ccgtccatta ttctagcaga tgaaccaact gctagtttgg
    55741 attcagaaaa ggcacgagaa gtagtcgata tcttggcaaa agaatcaaaa gacaaaaata
    55801 aagcaacgat catggttact cacgatacac ggctgattga caaatgcgat agaatattta
    55861 tgatggaaga tggtgtattg aaagaaaaag aataaccaaa aagcaggtgg aaaaatggtc
    55921 catcgataca acaaagatac acagcaaaaa attttgaaag aagcgactga cttgtttatg
    55981 tccaagggat atctcggcac ttcaacaaga gagatcgcac aaaaagttgg gatcacccaa
    56041 cccaatctct atcattattt cggtgataaa gaaaaactat atacggcagt tttagaaaac
    56101 cacttaaaag atgttggaaa agctttgaga gaaatcgttc aaacaagcga aacgggattt
    56161 caagtaacct tgacaaaaat ggcgcagttt ttgattgaga cacatctggt cgatttgttt
    56221 ctgatgcttc acgatcttga aagcaatctt tcaaaggaaa caagagatca tcttttcttt
    56281 ctatggaaga aaaattatcg tgaacctttt gaagaaatct tttcagcaaa ccaatctgtg
    56341 ctaagaaatg ggatttcaaa agaaatcgca gcaaggcatt ttttcttagt gttagcacct
    56401 tacatcactc ggtcgaaaag acctgtggaa gaaccgctaa atgtggcgca attgatcgat
    56461 ttatatttga atggtgtatt aggagaagcg taaagctgtt atatagggag aaaaatagtt
    56521 aggtgaagaa gcaagatatg acgaagatcg ttatatcttg ttttttttat ataggtagtt
    56581 tttcataaat acaaatttgt tattctctca tgattatcag ggtatatttt tatttattat
    56641 gtcggtgttc caggaagtgt tttaatttaa taacgaagaa attaattgtt tgtagaatga
    56701 aggaaactat ttattgggta gatgaatcac cacgaatagt caaaaggaga tttcaggata
    56761 tgccaaaaat gaaaaaaatc attttagcag taatgttatt ttctacggtt atatctttta
    56821 cagccccttt tttgcgtact taagctgatt ttaagttttg acccttagtc tggatctacg
    56881 aggtgagagt caagaatgaa aaaaataatt ggagcttttg tatttgcaat cattatcatt
    56941 attatctgtt ttcaaataga tgtttttggt caaaaaaaga tagttggaca aacggtcagc
    57001 agtacgaaca gtacggttac aaagacaaag gaatcatttg atgatacaga acaagagaca
    57061 ttaatcaaaa tcggaaaaaa tgaccgtaca ctatatacag atgactcgct aactacccca
    57121 cttgcaacta taaacggcgg agagctggcg gagtttcttt ctgaaacaaa aaatgcttat
    57181 cagatcaaga caaatgatgg ctatactgga tatttagccc tcgaagatgg aaccaaagtc
    57241 acaaagaata tacaaacaaa accggaagag ctatctgatg cagtgattgt attagatcct
    57301 gggcatggcg gaaatgatac tggggcatta agcaatgatg aacaaacaga agaaaaagat
    57361 ataacattaa gtacagccat aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt
    57421 tatttgaccc atactacaga tgaattagta cagcttggag atatatgcga ctacagtgaa
    57481 gaaaaaaagg cagatgtctt tatcagttta cacgcagact ctacggaata tgcgaatgaa
    57541 gcaactggaa tcacgacata ttattactat ggacaagagg aaacattagc acagacaatt
    57601 gctgactcct tcactgatct gcctctggat tcaagaggaa tctccactgg gaactatcaa
    57661 gttcttcgag aaaatcttca accttctatt ttaatcgaga tgggttatat gaataatgat
    57721 agtgatttaa aggaattagt aacagacagt tatcagcagc agattgctgc aagtttgaca
    57781 caagcattga ccacttattt tcagtaataa ataagcccag ccaaacaaaa atagctcctc
    57841 atatttttcg tttggccggg cttattatcg cagatgcaag cttttgaaca ccgtttaagg
    57901 aagaggttgt gagcctgccg tttaactccg cgtcacaagg agcaatttca aaaaacagct
    57961 tctcatgttt gatgactatt gtgacttgtg accgaggagt tggcatgaga acaccgttta
    58021 ttcggaacaa gggactgtga catgactttt gtcacagttc cattattttt ttagcagctt
    58081 caaagctttt tctgtattgg caaaatgaag tttggcatat ttttcaagca taggcatgcc
    58141 gcctttctcc aatagttttg ccgctacttg gtcagatttc gttccagctc ctgatggaag
    58201 ggtgattcca gcttcagctg atgctttgtg taactcttcc aaaaagctgg cacgactgat
    58261 gatagaagca gcagcaacag ctaaatgata ttgttctcct ttagtaacga agtacagttt
    58321 ttcttgtaat tgattttttt ctaaacgcgc atatttttta aaatttgctt ccggcgtaaa
    58381 ctgatcgatc aaaatcgctt ctggtttttc tggctcgatt ttttttagca gcaaatggat
    58441 cgcttgattg tgcaaagcga ctttcatccg aacggcattg tattttggtt ggatctcatt
    58501 gtatttttct ggagataaga caagcagttt ataggggatg gtttttttta agatgtcagc
    58561 aagctggatg atttggctat cttttaactc ttttgaatct ctaacaccaa gtttacgtaa
    58621 ttctgcaagc tgatcacgtt tcacataagc agcacatact gttagcggac caaaatagct
    58681 gccatttccg acctcatcac tacctaaaac ggataattga ctgatatttt ttggcaaaga
    58741 agaggctgtt tttgctggct tggcttgttt atcctgtgcc tccccccatt tatcagcttc
    58801 tattgctgca ttcgtacctt gaaacatcac ttttccggat gtataagcgg taatggtcgt
    58861 cccgtctttt tttgcagcaa agctagtata aggaatctgt ttatttaaca aataagagcg
    58921 atagtatgct ttcatttgac taagttggtc gtttgttgct ttgataatga cgttgctcat
    58981 aaaattctcc tcgtttttat acataaaact ataccgcaac tcacgacttt tcgttttcta
    59041 agagattgcg agacatagca tttttttaaa gtttatcata taatagttaa gtatgtgaaa
    59101 aatatttgtg gagaacggtg aaagaaccaa cttcatggta cactaaataa aactttcatc
    59161 aaataggagg aaatgattcg tatggcgcac gaaaaaacac gctacaaagc agtgattgcc
    59221 aaccaaacat atactattat cggacgggaa accaagcatc atatggatat cgtaacgaag
    59281 ctgatcaatg aacagttagc agaattgaaa caattatcac cacaaatgga taatgaacaa
    59341 gcagcaatct tgatggctgt caatgcgctt tcggatcaat tgaagaaaca agaaagaatc
    59401 ttggagctgg aagaagaaac agcagaatta aagaaaaaaa tgatcaaatt tacagagctt
    59461 gaaaatcgtg tgaaacgcat tgaagcaatc gagaacgaag ctcgggaagt attgaaagaa
    59521 aatggtcaag cagatcatac cattaaaaat catgtggaag cacaacagat tttaaacgag
    59581 aaacgaaaag gacaaattaa acaaaaatct tctaattaag atccttttat caaaataaga
    59641 aaaatttaaa aaagttagaa gagaaaggaa cgtagcatgc tgagtttgct gattttattt
    59701 ttattgctaa ttgcgttttt ttctggagca cgtcgcgggt ttgctttgca aatcatattc
    59761 gcgattggat atgtattgtc atttattgct gcccagcatt tttacaaacc attagcaagt
    59821 catttggaat tatacattcc atacccagct gtcaccccaa catcaaagtt agcatttttt
    59881 gatcaggtat ttgcttttca cctagatgaa gctttttatg caggaactgc ttttctgatt
    59941 attttgctaa ttggctggct gcttacccga tttgtggggg tttttgtcca tggattgacg
    60001 tatgtgccga tcttgagaca ggtagactgg attgcaggag gcatcctgtc actaatcatg
    60061 gcttacgtta ctatattttt gattttgcag ttacttgcct ttgttccatt agatgtggtc
    60121 caaaatcaat tcggcgagca tagtttcgct cgttttatcg ttgagagaac gccatttctt
    60181 accaacaaga tgtatgagct ttgggtaacg aatattttga attaaggaaa atagtgctgg
    60241 aaaatatttc gttttttgta cagagtagtt tatttaagaa ggctgcgtag cgtatgtccg
    60301 gcacagctct tttttcatag tgaaagataa ggtgataaaa tgaataaccg aatccttgaa
    60361 acattggaat ttgaaaaagt caaacagatg gtcagacaat ttgtagtgac tgcacaagga
    60421 aaagaagaac tggcagaatt ggtaccagtg agtgagaaac aaacgatcac aaactggctt
    60481 caagaaactg aggatggatt gaaagtgcaa cgtctgcgag gcgggatccc tatacctaaa
    60541 cttgaaaata tccgtcccca tatgaaacgg atcgagatcg gagcagactt gaatggagtg
    60601 gagcttgcac aagtttccag agtattgtct acgacaagcg aattgaatcg tttcattgat
    60661 gatctttctg acagtgaaat cgaatttgca cgtttgtata tgtgggcaga tcagttagtc
    60721 acgatccctg ttttgagccg ccgtttaaag gaagcaatcg atgaagacgg acgcgtgact
    60781 gatgacgctt ctcctgagtt aaagagcata agacagaaca ttcggcgaag tgaacaagct
    60841 gttcgtgaac agttagatgg gatcgtccgt gggaaaaatg caaagtattt aagtgatgcg
    60901 atcatcacca tgcgaaatga ccgctacgtt atcccagtca aacaagaata ccgcggtgta
    60961 tttggcggtg tagtccacga tcaaagtgct tcaggacaga ctttatttat tgaaccaaaa
    61021 caagtggtgg atttgaataa tcgtttgcgt caataccaaa tcgctgaacg aaatgagatt
    61081 caacgtattt taagtgaact ttctgctgaa cttgttcccc atcgtcaaga aatcatccac
    61141 aatgcttatg tgattggtaa aatggatctg atgaatgcaa aagcacgatt tggtaaagaa
    61201 gtaaaagcca tcgtgccggg aatcagtgaa gacaatcatg tcgtcttgaa acaagcaaga
    61261 catccactga tcgatcagga aaaagtagtt tctaatgaca tcacaatcgg aaaagactat
    61321 caagccatcg tcattacagg acctaacaca ggtgggaaaa cgatcacgtt gaagacttta
    61381 ggtctgttac aactgatggg gcaagcagga ttaccgattc ctgcaggtga agaaagtcaa
    61441 atcggtattt ttgaggaagt atttgcggat ataggagacg aacagtcgat tgagcaaagt
    61501 ctatcgacct tttcttctca tatgacgaac actgtagata ttttatcaaa agtcaatgaa
    61561 aaaagtctgg tattatttga cgagctcggt gcaggaacag atccgcaaga aggtgctgct
    61621 ctagcaatcg caatcttaga tgatcttggt aaaaagtctg cttatgtgat ggcaacaacg
    61681 cattatcctg aattgaaagt ttatggatac aatcgggcaa atacgattaa tgccagcatg
    61741 gagttcgatg tggatacact aagtccaacg tatcgtttgc tgattggcgt tcctggacga
    61801 agcaatgcgt ttgaaatctc tagccgatta ggtcttgata cagaagttat tgatgaagcg
    61861 aagcagttga tgaatgatga gagccaagat ttaaacgaaa tgatcacaga tttagagaat
    61921 cgccggaaaa tggcagagac cgaatatctg gaaatgcgtc attttgtttc tgaggcacaa
    61981 gaacttcacg atgatttgaa agaagcttac agctatttct ttgaagaacg tgaaaaagaa
    62041 atggaaaaag caaagaaaaa agcaaacgaa gtcgtgtcag aggcggaaga aaaagcagaa
    62101 aaaatcattg ctgatattcg taaaatgcaa cagcagattg ggcaaggaaa tgtgaaagag
    62161 catcagttga tcgatgcaaa gacccaatta gcaaatctac atcaagaaga aactttgaag
    62221 aaaaataaag tattgaagaa ggcgaaagaa caaaaaacgt tgaaaccggg agacgaagtg
    62281 ttggttacga cttacggcca aagagggacg cttttacgta aaaacgggaa tcagtggcaa
    62341 gtagaaatcg gtatattaaa aatgaatgtg tccgaagacg agctgacgcc tgttgctcct
    62401 caaaaagagc cgacacaacg agttatccat gctgtacgat ctgaatctag tagtcacgtg
    62461 ccgaatcaat tggaccttcg aggaaaacga tacgaagaag cgctaagtga ggtagatcaa
    62521 tatttggatt ctgccattct agctggttat cctcaagtga ctattgtcca cggaaaagga
    62581 acaggcgcac ttcgcaaggg aattactgat tatcttaaaa accatcggag cgtcaaaagc
    62641 tttgagtttg caccggcaaa ccaaggcgga aatggtgcga caattgttaa atttaagtaa
    62701 agcttactaa aggtaagcag atggttcgct atccaagtat agaaatgcta tactaatcat
    62761 agattttaaa aatggaggtc tttgatatgt cacaagtaat tacagataag acatttaatg
    62821 aagaaacaga taaaggactt gtattgattg atttttgggc aacttggtgt ggtccatgtc
    62881 gtatgcaagc accgattttg gatcagttgg aacaagaata tgatgaagaa gaattcagaa
    62941 ttgctaaaat ggatgtggat gaaaatccag aaactcctca acaattcggt atcatgagca
    63001 ttccaacatt aatgttgaaa aaagatggtc aagtagtaga aaaagctgtt ggtgttcatt
    63061 caaaagaaca actacgtcaa atgatcgatc aatatttata aaaacttaca gcaaaaataa
    63121 gctgagggtg ggactgaatc cagttccgtc ctcggttttt ttgcggttga gttaaggtta
    63181 ttcaaattaa tattttttga gtataattac gttgtcaggc tggattgttt ttttgacaga
    63241 catgctataa taactttaat tgaatatgaa ggggagtacc agatgaacga acgaatcaaa
    63301 aacaaattag ctttacttcc tgatcagccc ggctgttact tgatgaaaga taaaaatgga
    63361 acgatcattt atgtcggcaa agccaaaata ttaaaaaatc gtgtccgctc atattttact
    63421 ggcagccata atacgaaaac ggaacggctt gttagtgaaa tcgaagactt tgaatacatc
    63481 gttacagaat cgaatatcga agcattgctc ttagagatca atctgataaa gaaaaatgat
    63541 cctaaataca acattatgtt aaaggatgat aaaacctatc ctttccttaa gataacgaat
    63601 gaaaaatatc cccgtttggt gattactcgt aaagtactaa aagacaaagc actgtatttt
    63661 ggaccatatc ccgatgtcgg tgcggcgaat gagacaaaga agatcctcga tcgattattt
    63721 cctctgagaa aatgcaaacc tagtcagacg aaggagcctt gtctttacta tcatttggga
    63781 caatgtctgt gtccttatta tttcgacgta gatccgaaag tctatacgaa aatcgttgat
    63841 gaagtgaaaa agtttttaaa cggaggacac gaaaaaatcg agtcagagat ccatcagaaa
    63901 atggaaaaag ctgctgaaaa catggagttt gaaaaagctg cagaataccg agaccagatc
    63961 cgtgccattg agacaatcat gactcgccaa aaaatgacaa atactgattt actggatcga
    64021 gatgtatttg gttatgcgat tgacaaagga tggatgtgtg tccaagtgtt tttcgtaaga
    64081 caaggaaagc taattgaacg agatgtttca atgtttcctt tctataacga agcagaagaa
    64141 gatttcttga cttacctcgg tcagttttat caggaaaatg agcatttcat tcctaaagaa
    64201 gtcttgattc ctgatacgat cgacaagccc agtgtagaag ctttgttagc tacgaaagtg
    64261 ctgcaaccaa aacgaggaga aaagaaaaaa ttagttgaat tggcgaataa gaatgcctca
    64321 gttgctttga atgaacggtt tgatctgatt gccagaaaac aggaacggac gatcggagca
    64381 gttgaacgtt taggaaacgc gatgaatatc ccgaccccaa tacgtatcga gtcttttgat
    64441 aactctaata tcatggggac gaatcctgtg gctgcgatgg tcgtattcat tgatggaaaa
    64501 ccggcaagaa aagaatatcg gaaatataaa ataaaaacag tcaacggacc ggatgattat
    64561 gcatcaatga gagaagtcat ctatcgcaga tattcacgag tgattcgcga agggttgcct
    64621 ttacctgatt tgatcttgat cgatggagga aaaggacaag tagatgtggc aaaagatgtc
    64681 ttagaaaatc aattaggaat cgatattcct attgctggca tggcaaaaaa cgataaacat
    64741 aaaacaaatg agttgctatt cggtatagat ttggctgtag taccgcttga gcgaaattca
    64801 ccagagtttt tcttactcca gcgaatccaa gatgaagtcc atcgattcgc aatcactttc
    64861 catcggcagc tacgcagtaa aaacagtttt gcttcccgat tagatgaaat tgaagggtta
    64921 ggaccaaaac gaaaaaaaat gctgcttaaa gagttcaaat cgttgaaaaa tatcacagca
    64981 gccacgacag aagaattaca agaaatcgga ctgccgaaaa atgtcgcaca aaacgtattt
    65041 gataaattac atcaggaatg aggaaagggc actttacaaa gaaagtaaag tgtcctatca
    65101 ttttatgtac aacaaaaaga gcgtttacgt tttgttggta aataataaat cgcttacgtc
    65161 tggtgtctaa ggatatatgt gatttcttga agaaggagtg aagaaatgtt agaagtcaag
    65221 gatcttgtta aaacttttgg gaactacaca gctgtcgatc atgtctcttt ccaaatcccc
    65281 gatggaaaaa tcatggggct aattggccaa aacggggctg ggaagacaac gacttttcgt
    65341 ttgatcttgg attttttgac acaagaccaa ggagaagtgt tatggaatgg ccatcatctt
    65401 ggggagaaag attatgatgt catcggttat cttccggagg aacggggact ttatccgaaa
    65461 gtaacgattc aagaccaact gctttatttt gcagaactta gagggaaatc aagaaaagag
    65521 attgaaccaa aaatcgattt ttggatggaa aaatttcagg taaaagggaa aaagacggat
    65581 aaagtaaaat ctttgtctaa aggaaatcag caaaaagtcc agctgatcgc cacgttaatc
    65641 catgaaccta aattgatcat tttggatgag ccattcagcg ggttagatcc ggtaaatgct
    65701 gaattgctaa aagatggaat attggaattg aaaaaacatg gttcatgtgt cattttttct
    65761 agccacaata tggataatgt agaaaaaatc tgcgatcatt tgatcatgtt gcgaaacgga
    65821 aaaatggttt tgaatggaaa agtacatgag attcgtgaat catttggccg tacgaagtta
    65881 ttcttggaat ctggtttaag ccaacaggaa gtagaagaaa tcgaaggcgt gaaaaaagtg
    65941 atccttcatg aagacaatac gttagagatt accttagaag atcctgaagc tgggaaagaa
    66001 atctttactc gtgcgactca gttcggctac attcctatgt ttaaccagca accgccaact
    66061 ttggaagaga ttttcaaatt gaaagcaggt gaaatcgatg cgtaagtttt ggattattac
    66121 caaagatgtc tatttaaaaa atgttaagtc gatttctttc ttgatcatga tattagtccc
    66181 ttttatcatg ctgggtatca tttatgtagc aggaaacttt gctcaacaaa atagtgatgt
    66241 caataaaatc ggcgtattgg ctgataatga gcaaatcagt cagcaaatga gccaagtcaa
    66301 aacagatgat tttgagttca aagcagttga ttctgaagaa aaagcacaaa aagagctttc
    66361 ggaagaaaaa atcgatgcgt atttagtagt ctcaactgag aatgataaga taaatgggat
    66421 gctttatagc gaaaattcat taggacaaag tacacaacta ctgatacaac aacaactgac
    66481 tggcttgcaa tcgatgcttc gagcaagtca attaggcatt tcaccagaag aagtagctag
    66541 cttgagccaa caagcaagtt tgactcgaca aaaagtcaat tttgattcaa aaggaaaaat
    66601 gacagttgga gaagataact cgacagtcca atatgtcgta agttatgtag caacgattgt
    66661 cttgttcatt attattttga cgtatgcgca gatcattgca caagagatcg cttctgaaaa
    66721 aggcacgcgg atcatggaag tgatcctgtc cagtacgact gcacaaaagc atttttacgg
    66781 aaaactaaca ggtgttttac ttgttgcatt aacgcaaatg gcattatacg gtattatttt
    66841 tggtatagga tacagtcaat tcaaagatat ggaaatggtc aaaaatatat tagacggtat
    66901 ctcattggat aacttgattg gaccattctt gtggtattct cttctattca tgatctttgg
    66961 cattttgatt ttttctgttt tagcagcttt atgtggctct ttggtcaaca aagcagaaga
    67021 tacagcaaaa gcaattttgc cagtgactta tctatctcta ggcggatata tgcttggatt
    67081 gatactagga gcttcagatc caaacaatat cgttattcgg atcacttcgt atattccatt
    67141 cttatcttca tatattatgc cggttcgctt agcaaatgag acagtcggta tgggtggagc
    67201 attgatttcc ttgttggtac ttgtagccgt aacattctta ttgatgatct tgtctgcaaa
    67261 catgtacaaa tcgaatgtac tcgtgtatag cgaaggcgga ttatggagtt cattgaaaca
    67321 atcgatttca attatgagaa atgaacgaaa aaaagcataa aatatagaaa aatatagaag
    67381 gaagctggac atttattgtt cccagcttct tttttgtata gacctatttc tattttttta
    67441 ttatattgga tatatatatt cattgaaaat agagcataac aactttataa tgttgagtat
    67501 accaattttt ggaggcgttt taatggaccg ctatttagat ttactttcag agaagttccc
    67561 tacaacggaa gatgtcatca cggaaatcat caatctcgaa gcaattttgc agcttccaaa
    67621 aggaacagag ttatttttga gcgatataca tggcgaattt cctgcttttg atcatattct
    67681 gcgtatcggt tcaggaaatc ttaaagaaaa gatcaaagac cttttctctg aacaaatgac
    67741 ggaaacggag atcagccaat tcactatttt tacggcttat ccagaatatg tgttgacgac
    67801 tgattggtac aaaaaacaag ataaatccca gctgatccat cgtttgatcg atcttttacg
    67861 gtttacgaca gtcaaataca ctcgatcaaa agttcgaaaa ggattgccga aagaatatag
    67921 ctatatcatt gaggaactct tgtatatcga tgatcgtatc aacgggaaaa aagactatgt
    67981 aaaaaaaatc attgaacaac ttgtcttgat gaaggaagaa gaaaaatttt taacaaaact
    68041 tgcgcagacg atccaaaaat ctgtcatcga tcatttgcat atcgtgggtg atatttttga
    68101 tcgaggaact caagcagcca aagtaatgga tcgaatcatg gatttttcct ctgtagatat
    68161 ccagtggggg aatcatgata ttttgtggat tggtgcgtat tgcggctctg aggcatgttt
    68221 attgacgctt ttacggattg ccgcacgcta caactattta tttgaattag agaaagaata
    68281 tggattaaat ttacgtccat tattttcttt tgcccatcaa acctatcaga agaatccagt
    68341 atttacccct aaaaacagga aagatctatc tgaaagagag caagaagaat tagaaaagat
    68401 ccatcaagca ctttctatcc tccaattcaa atcagaacat cagttgttga atcgacgacc
    68461 tgaatttaaa atggacgatc gtaaattgtt ggaaaaaatc aactatgagg aatcaacgat
    68521 cgttttagaa ggtcagctct atgagttgaa agggacttgt tttcaaacga tccagccaga
    68581 tgatcctaaa aaattcttgg aagaggaaca aaaagtgatc gatagtttga tgtattcatt
    68641 ccagcactcg ttaagaatgc aaaaacacat gacgtttttg atcgaaaaag ggggaatgta
    68701 tctcacgaac aatcagcatg tactgttcca tggctgtata cctgtagatg aaaaggggca
    68761 gctcttagca tttgaattag accaatctta tcgcggaaaa gaactgctgg gattttttga
    68821 aaaacagata actgaaagcg caaaagattt gactgcaaat gaagatttgg cgaccgattt
    68881 gatttggtat gcgtggagcg ggccattttc gcctttattc ggcaagagta aaatggcaac
    68941 ttttgagcgc tattttctca cagagcctca tacgcacgtc gaaaaaagca atccctatta
    69001 tcacttgcga gatgaagagt ggttcagtga aaaaattttg gcagaattcg atgcaaaaga
    69061 agaaggttca gcaatcatca atggacacac gccagtaaaa gtaaaaaaag gagagtcacc
    69121 gatcaaagca aacggaaaag catttgttat tgacggaggt ctatccaaag cttatcaaaa
    69181 aacaaccggg attgctggct actcattact atgcaattct tacggtttcc aaatcgtgac
    69241 acattatccg ttcttgccta ttgaacaaca atttgcaaaa aaatctgatc aaacgaatgt
    69301 aaaaaaagtg atcgagcagc agctcccacg caaacttaat cggaatacga caaaaggaat
    69361 ggaattacag caacagatta ctcaactcca aaggctgttg gattatcgaa aggacgattg
    69421 agaaaaatgc tagccaacat tgctcaatag actaaaaagc gactgcaaca aaaggcgtgt
    69481 cgcagtctcc ttcggaatta gctcaaaaaa cggtaaaata ttagaagcta tttttctgtt
    69541 tatttctcta atactcaggt cagggcgctg atttcacgac ctcttcctta aacggtgttc
    69601 tcctgccaac tcctcggtca caagtcacaa tatccaacaa acatgagaag ctgttttttg
    69661 aaattgctcc ttgtgactca gagttgaacg gcaggctcac gacctaatca gaaaaacgat
    69721 taaaattcat tcacaaagaa atcgaataaa cgctgttcag atgaatctac acgatgagaa
    69781 agttccggat gccattggac accaaggatt ttgtgcatat tatctttact ttggactgct
    69841 tcaatgagtc catcgttgga aaaggcgatg gcttttaaca aaggagaaag atctttgact
    69901 gcctgatgat gataggaatt cacaaagtat gaatcaggga gaaggtcact taataaactg
    69961 tccgaaacga ttttgacttc gtgagttgca aactgcgggg cagtgggctg ttgttcgtgt
    70021 tttacggacc attttggata taatgaaaga tcttgataaa gtgttccctc caacacgaca
    70081 ttcaatagtt gaagtcctcg gcagactgca aaaatcggtt ttctttgttt caatgcttcc
    70141 aagatcaatg cctgttcgaa ttggtctcgt tgaatatttg tttccgtcag ttttggatga
    70201 gggtcttcca tgtaaagttg cggactaaca tcctgaccgc ctgcaagaat gagtttgtcg
    70261 attttctcaa ttagttgagg cgctgaatct ggagacatga ctggcagaat aagaggtaat
    70321 ccttgagcat ctaaaactgc atccacaaat ccctgcggtg tatagcttac ttgatttcct
    70381 tggaaagtat ctgtcgctcg aatcagttga ttcccggcaa tgccgatgat tggtttcatt
    70441 tttattcccc ctaaagtaga ctaattgtaa caaggattta aaaaaattta aactatgtaa
    70501 gacttgcccc tatacttatc tgttcttgct gtgttactat ctgtaaagag aattttcgtg
    70561 tgaaattcat gacgatagtt gaaaatattg cttaatttgt tataataaaa agtaagcaga
    70621 aataaaaagg ttgggcgtaa gcttcaagga tctagttctt caaggggtga gaaggacatt
    70681 ttattgaagg ggcctgccta tactaagtta tctttagagg tacatacttt caatgaaaaa
    70741 agaaagcatg tacctctttt ttaaatcgaa aggaagtgaa gcaagtgtta gaagctttgg
    70801 aacaaatccg aaaagcagaa gaagaaaatg agaagcgtgc tcgaacccta cggcagcagt
    70861 tgaagaccta tgcagaagaa aaagagcaag aattggagat aatccaaacg aacagtcggc
    70921 aacagctgaa acagttggta gaagaaaaag aacaattcga aaagcaagaa ttagaaaaag
    70981 aaaaaatgaa attgaaagca gaagcagaca aggtgcaagc aactttaaaa gaccaatatc
    71041 aaaagcatca gagtcaagca atcggtgcaa tcattgaaag ggtgaaagaa acttatggcc
    71101 gtcactaaga tggaaaaagt gaccctcatt tcagataaaa gaaatcagga gaggatttta
    71161 caagcagtac aaggaatcca aaatgttgaa atccgggatc tgtatcaaaa tagaacaaac
    71221 aaccagtggg tagaaaaata ttttccagat accacgatta ttgataaaga agcaaaatta
    71281 agcgctttag gcaatcggct gaaagacatc caagaagcta tccaattcat acaacaccac
    71341 ggcgatagcc gtcaaaagaa actccatttg aaacgtcaag aactttcctt acaagacttg
    71401 gaagcaaatt attccgaaga aaatttcatg aataaattag aagaagtcct tgatttaaaa
    71461 gaaaagtggg aacagctaac tgaaaaacgt gatcgtttag aagaagagga agaatggctt
    71521 cttcattggc aacagctgga tattgctcca agtatgtatg caagtaagac gaccattttt
    71581 gagatgggga ctgtgagtgc agcaaatttt gaaagtttca aggaagaact aagtaagctt
    71641 gatgacgttt atatggaaga aatagattat acgccaaaac aagtttatct ttcgtatgtt
    71701 gctttaaaaa aatcagttgc tgctatagaa gaaattgctg ggaaatacgg gttcaataaa
    71761 gaaacgtatc cttatgaaca aaatcctaaa gaaaaattgc aagaaaccaa acagcaatta
    71821 tccattgttc acgagcagca aaaaaagata acgacagcgt taggtcagtg cagcggctat
    71881 atccaagaat ttgaatgggt agaagaagtc acacttgccg ttgcagaacg ggaaaaagta
    71941 aaagaacggt ttatccatgc cacttatctg atcgttttgc aaggttgggt agatgcagaa
    72001 gaaaaacaga atttgatgca tgtgttaaac gaaactgtat cagaagaaga tatatacgtt
    72061 agtttcgaaa caccaaactc agaagagatt cagcaggaag tccctactaa attgaaaaac
    72121 catccgctta tcgaaccttt tgaattgctg actgaaatgt acagtctgcc aaaatatgaa
    72181 gaagtagatc caacgccttg gatgacacca ttttatcttg tcttcttcgg gatgatggtc
    72241 gcagatgttg gttacggatt gctgatgctc attgggacaa tactagctca aaaactattt
    72301 gttttacccc gcgggatgaa acgtttcgta aaattctttg agattctctc ggtaccatcg
    72361 atcatctggg gattgatcta cagttcattt ttcggacagg cattaccaaa agaactattt
    72421 ggtatccgct tgcctttccc aatcctatct acgacggatg acgtcaatac gattttgatt
    72481 ttatccgtga ttttcggtct gatacagatc ttggttggat tattcgtggc agcaaaggaa
    72541 aatatcagga ggaaagatta cttgagtgct gtcagtgatg gttttgcctg gcaagggatc
    72601 ctgattggga tcgttattgc attgattggt gtcatgttga taaaaaatac agcatttgtt
    72661 tatcttggcg cggggctatc gatcattgct gctttatgta tcttaatcgt gccgattatc
    72721 caatcgccgt ctaaagtcaa gggtgctgcc aaaggagcgt ataatcttta cggattgact
    72781 ggttatatcg gtgatttagt cagttataca cgtttgatgg cactaggtat ttcaggcgga
    72841 agtattggcg cggcattcaa tatgctagtt gctttcatgc cgccagccgc tcgattcagt
    72901 gtagggatcc ttttgatcat cgctttacac gcactgaata tgtttttgac actgttaagt
    72961 gcctatgtcc atggtgcacg attgcagtat gtcgaatttt ttggaaaatt ttatacagga
    73021 ggcggacgtg cctttgaccc gctgaaaacg gcggaaaaat acgtcaacat caatcataag
    73081 aaaaaaaaca ataaataatt ggaggatttt tatacaatga tggattactt aattagtcaa
    73141 aatggtggaa tggtatttgc agtattagcg atggcaacag cgacgatttt ttcagggatt
    73201 ggttcagcta aaggtgttgg aatgacaggt gaggcagcag cagcgttaac aacaagtcaa
    73261 cccgaaaaat tcggacaggc tttgattctg caattgcttc caggtacgca agggttgtat
    73321 ggattcgtta tcgccttttt gatttttatc aacttaggaa atgatatgtc agttgtacaa
    73381 ggattgaact ttctaggcgc ttctctgccg attgctttta caggtttgtt ttcaggtatc
    73441 gcccaaggga aagttgcagc agcaggtatc caaattttag cgaaaaaacc tgaacatgct
    73501 acaaaaggaa tcatttttgc tgcgatggtt gaaacatatg cgattttagg tttcgttatt
    73561 tccttcctat tagtattgaa tgcctaagca taaaggagga aaagcagatg aacgccattg
    73621 aaaaaatcat ctctcagatg aatgaagcag cagagcaaga aagagcggcg ttagagcaag
    73681 aagagcgaat gaagatcgat caaaactttg aacaaaaacg tacgcaaatc gaaacagaac
    73741 atcaaaaaca aaaagaaaaa caaatcgaat tacttgaaaa aaaataccgt cagcttagga
    73801 atcgccaaca agtagaagta cgacaagaaa atttgaatgc gaagcaggaa tttttacgac
    73861 gattgtttgc agatgcaata gctgaaatgg agaattggga tgaatctgaa caaatccagt
    73921 ttatcaaaaa ttcattgtat tcattacctt tgacaggcaa agtaacattc attgctggag
    73981 aaaaatcagc agcttatctt tctcagacat tgctggatga atggaacaat gaacttccct
    74041 ttatgatggt tttaagtgat gaaactgttg ctgatcaagc gggttttctg ataaacgatc
    74101 aaggagttca gtataatttt cttttcagca gccttgtaca agatatccaa ggaacgatga
    74161 gttttgagat tgccaatcaa ttattcgaat aaggagggat cagtgtatgg aataccacga
    74221 actaaatccc ttgattcgcg gaagagagct tgaacttttg tccaatgaga catttgaacg
    74281 gatgattcaa acaaattctg tcgaagcact tggtgaaata ttgaaatcca cgatttacag
    74341 tccatatatt tatgacggat atgaatatga cttcgaacag aatcttttaa aggagcagag
    74401 ccgtctattt cgctggttaa aggaatcagc accggagcct gaaatcgttt ggatctatac
    74461 gatgcgctat actttccata atctgaaggt tttgacaaaa gccgagatga caaatcaaaa
    74521 tctggaccat ttgtatatcg acgatggatt ttattcatta gaaaccttga aggatgccat
    74581 tcatacgcaa gtttcaaatg aactccctga aagcattatg gacagtatac gagaagtacg
    74641 tgattatttt gaagagtcta ccattcttca gggaattgac gtgatttatg atcgacagtt
    74701 tttgacagag cagcgacggc ttgccgataa gctaggatat caagaattgc tgacagaagt
    74761 cattgctttt attgacttga ccaatatcac aacgatggct cgaggaatat tgcagaaaag
    74821 aacatatggg ttcatgacga cggtactttc cagctcggga agtatcgaaa aagaagtatt
    74881 tttgaacttt gtagataaag atatggaaga ttacacgaat tttctattag agacagatta
    74941 tgctgatttt ctgcgccctg tcatccgtga gggaaatctt gatctcgtaa agcttgaaca
    75001 gttgaaagat gattatctaa gttcattgta tcaagaagca caaacccagg ctttcggacc
    75061 actgccacta ctagcctttt tgaacgcaaa agaggtagaa agcaaaaacc ttcgtttact
    75121 ggttatcggc aaaagaagcc atttcgaacc agaaacaatc agaaagcggg tgagacaagt
    75181 ctatgacgca taagatcggt gtagttggcg acaaagattc tgttttgcca ttcaaattgt
    75241 ttggctttga tgttcgttat ggtacaacca agcaaaccgt tcgtcaggca attgaagaaa
    75301 tggcaaagaa tgagtatggc gtgatttatg tcacagagca atgtgcagca ttgagcccag
    75361 aaacgatcga acgttacaag gaacaaatga tacctgctat cgtattgatt cccaatcatc
    75421 aaggatcatt agggataggg ctggaagaaa ttcaaaaaaa cgtagaaaaa gcagtaggtc
    75481 aaaatatctt atagtatgaa aaggagatag aaattttgca aattggaaaa atcataaaag
    75541 tctccggacc tcttgtaatg gctgagaaca tgtctgatgc cagtatccaa gacatgtgtc
    75601 tagtgggaga tctaggagtt atcggagaaa ttatcgagat gcgtggcgat gtggcgtcta
    75661 ttcaagtata tgaagagact tctggaattg gtccaggcga accggttcgc tctactggtg
    75721 aagctttatc tgttgaatta ggaccaggga tcatttcaca aatgtttgac ggaatccaac
    75781 ggccattaga tacctttatg gaaatcacac aaagtaattt cttagggcgc ggagttcaat
    75841 tgcccgcatt ggaccatgag aaaaaatggt ggttcgaacc aacagtagaa gccggagaaa
    75901 cggtgagtgc tggagatgtt atcgggatcg tagaagaaac aaaagttata aaacataaaa
    75961 tcatggtgcc aaatgggata aaaggaacga tcaaaacaat cgaaaaaggt tcattcacta
    76021 ttgatgaaac agtatgtgtc attgaaaccg aaaatggtga caaaaatttg acgatgcttc
    76081 aaaaatggcc agtaagacgt agtcggccaa tcaaagaaaa attaaacccg gatgcaccca
    76141 tgatcactgg acagcgagtg attgatacat tcttcccagt gacaaaagga ggagcagcag
    76201 ctgtacctgg tccttttggt gcagggaaaa cagtcgttca gcatcaaatt gcaaaatggg
    76261 ccgatgtgga catggttgtc tatgtgggat gtggcgagcg tggaaatgag atgacggatg
    76321 ttttaaatga attccctgaa ttgattgacc ctaatacagg agaatcgttg atggaacgta
    76381 cggtattgat tgctaataca tcaaacatgc cagtagcagc tcgagaagct tctatctata
    76441 cgggaatcac aattgcggaa tatttccgtg acatgggtta tgacgttgct atcatggcag
    76501 actccacttc acgatgggca gaagcacttc gtgagatgag cggacgtttg gaagaaatgc
    76561 ctggtgatga aggttatcca gcttatcttg gttcacggct tgcggaatac tatgaacgat
    76621 ctggaagagt cattgcatta ggatcagaag gtcgcgaagg aagtataacc gcaatcagtg
    76681 ctgtatcccc gtctggaggg gatatttcgg aaccagtcac acaaaataca ttgcgggtcg
    76741 taaaagtatt ctggggtctt gattccagtt tagcccaaaa aagacatttt ccttcgatcg
    76801 attggataca aagctattct ctttattcaa cagaagtagg gaagtatatg gatcatatcc
    76861 ttcaagctga ctgggcatcc atggtcaccg agggcatgcg tattttgcag gaagaacagc
    76921 agctgaatga aatcgtgcgt ttggtaggga ttgattccct ttcagataat gaccgtctga
    76981 cattagaagt ggcaaaatcc attcgtgaag attatttgca gcaaaatgct tttgatgatg
    77041 tcgatacatt cacttcaaga gagaaacaat tcaaaatgtt gaagatgatc ttgacctttg
    77101 gtgaagaagg acgccgtgcg ttgtcgttag gtgcttattt aagtgagatc atggacggta
    77161 ccgtatcgat tcgtgaaagg atcggacgaa gcaaatatat cccggaaaca gaattagaaa
    77221 aactagatca aattattggt gaaatcaagc aaacgatgca aacgatcgtt tcagaaggag
    77281 gcatgagcaa tgattaaaga atatcgtacg atcggtgaag tcgtcggtcc attgatggcg
    77341 gttgaaaaag ttgctggtgt caaatatgaa gaattaatcg aagtccgtat gcaaaatggc
    77401 gagattcgtc gtggacaagt attggaagtc caagaagata aagcaatggt ccaaatattc
    77461 gaaggaacaa gtggtatcaa tttacgtgac tcttctgtac gatttttagg ccatccttta
    77521 gaactaggtg tatcggaaga catgatcggt cgagtattcg atggtttggg acgaccgaaa
    77581 gataacggac cagagatcct gcctgaaaag catttggata ttaacggaga agtaatcaat
    77641 ccagtagctc gggattatcc agatgagttt atccaaacag gtatctctgc aatcgatcat
    77701 ttgaatacat tagttcgtgg gcaaaaatta ccagtatttt ctggctctgg tcttcctcat
    77761 aaagaattag ctgctcagat cgcgcgacaa gcaacggtac tcgattcatc agatgatttc
    77821 gccgtagtct ttgctgctat tggaatcact tttgaagaag ctgaattttt catggaagat
    77881 tttcgtcaaa cgggcgcaat cgaccgttct gtcatgttta tgaatttagc aaacgaccct
    77941 gcaatcgaac gtatcgctac tcctcgtatg gctttgactg ctgcagaata tcttgcttat
    78001 gaaaagggaa tgcatgtttt ggttatcatg acagacatga ccaactatgc agaggcattg
    78061 cgagagattt ctgcagcacg gcgagaagtt ccaggaagaa gaggatatcc tgggtatctt
    78121 tacacgaact tagctacttt attagaacga gcaggaagaa tccgcggact aaaaggatcg
    78181 gttactcaaa ttccgattct aacaatgcca gaagacgata aaactcatcc aatccctgac
    78241 ttgactggtt atattacaga aggacagatc atcttgacta gagagcttta caagagtggg
    78301 attcagccac caattgatgt actcccgtct ctttcgcggt taaaagataa gggaactgga
    78361 cccggaaaga caagagaaga ccatgcagct acgatgaatc agctttttgc agcctatgca
    78421 caaggaaaac aggcaaaaga attagccgta gttttaggtg aatctgcttt atctgatgta
    78481 gacaagatct atgcgaagtt tgctgagcgg tttgaaaaag aatatgtcaa tcaaggattc
    78541 tacacgaacc gttcgattac tgaaacactt gatctagggt gggaactgct atcgatgttg
    78601 ccaagaaccg aattaaaacg aatcaaagac gacatgctgg acaaatatct gccagaaggg
    78661 aagtgagttc tgatggcacg attgaatgtg aatccgaccc gcatggaatt gactcgattg
    78721 aaaaaacagt tgacaactgc cacaagaggg cataaattat taaaagataa gcaagatgaa
    78781 ctgatgcgtc aattcatcct gttgattcga aagaacaacc agctgcgtca agaaatggaa
    78841 gagtctatga cagaagcaat gtctgatttt gtattggcaa atgcttcgat cacggaacct
    78901 ttcatcgaag aattatttgt tttgccggcg gaaaacgttg atttgtctat cgtagacaaa
    78961 aatatcatga gtgtaaaagt acctgtgatg aattttgaat atgatgaaca gctgacagac
    79021 acacctttgg aatacgggta tttgaattcc agtgccgaac tggatcggtc aatcgatcgg
    79081 tttactaccc tgcttccaaa acttttggaa ctgacagaaa tcgaaaaaac ttgtcaactg
    79141 atggcgagtg aaatcgaaaa gacacgtcgg cgagtcaatg cattagaata tatgacgatc
    79201 cctcaattag aagaaacgat ctattatatt cgtatgaagc tggaagaaaa cgagcgcgca
    79261 gaagtaacaa ggttgatcaa agtaaaaaat atgggtacca ctgactaagt ggtatctttt
    79321 tttaaaagag gaaaacgatg attaaacaaa gcaaacaaat aaagaaacgt ttgccggctg
    79381 ttcagcttct cgcattagga ttttttctcc tgattttagt tggcggcggc ctacttaccc
    79441 taccattttt tagtaatagt gggcatggga caaattttat cgatgcgctt ttcactgcaa
    79501 cttctgctgt ctgtgtaacg ggattgacaa cattgaatac agcagagcat tggaacagtg
    79561 ctggtcaatt tttgatcatg cttttgattg agatcggcgg tcttggtttt atgatggttc
    79621 cgattctatg ctttgcattg ataaagaaga aagtcagtct cagcacacgt attatattaa
    79681 aagaagcgct gaatctagaa gaagtatcag gtgtgatgaa gctcatgctt tacatcctaa
    79741 aattggcctt tgttatccaa ttgattggta cggttgcttt atcttttgta tttgtgcctg
    79801 aatttggctg gttgaaaggt atctggtaca gtttgttcca tgcaatctct agtttttgta
    79861 atgcagggtt tgatttgtta ggagacagtt tagccaatca ccagcaaaat gtttatttga
    79921 tcatggtggt atctgctttg atcatttctg gtgggttagg cttcatcgta tggcgtgatt
    79981 tactggaata tcatcagaaa aagaagatga cgattcattc aaaaatcgca ttaaccgtta
    80041 caggtaccct tttattaggc ggattcgttg tgttcttttt cacagagcgc aatggggcaa
    80101 cgctagtgga agggaatatg tttcaacgat tggcaaacac cttttttatg agtgtgacac
    80161 ctagaacggc tggatattat tcagttgatt acctccatat gagccatgca ggtctgattt
    80221 taacgatgtt tttgatgtac atcggcggaa catctgggtc gacggccggc ggattgaaaa
    80281 caactacgtt aggtgtgttg ctgatccaga tgcgttcgat gttgaaagga cgtacgagag
    80341 cggaagcatt tggccgtacc atccgacaag gcgcagtgtt gcgggcactt actttatttt
    80401 ttgttacgtt gacgttgtgt gtagtcgcca tcatgatttt atcggtgact gaaacgatac
    80461 ctaaaacttc tggcatcgaa tatattgctt ttgaggtctt ctctgcgttt ggtacagtag
    80521 gtcttacgat gggattgacg ccagacttga ctgcaatagg gaaattgatc attatagcgc
    80581 ttatgtacat tggacgagtt ggtgtattga ctgtggtctt ctctctgatg acaaaagcac
    80641 aaagaacaca atcaaaatac aaatatccag aagaaagtgt catgattgga taatttcatc
    80701 ttctgacaga aacctagtga tttagtaaaa taagaaaata aaataatttt tcttgcttct
    80761 tggatacttt aagtgcaaaa tgttcgttta ttttttgagg cactacccgt tgttgaacct
    80821 cgggtagtgc ctctttttta ttgaaaggaa tcaataagat ttgattcctt tatttatcaa
    80881 taggttataa ttcatatttt tttatttttt cttttacgat acttagtcca gaagctaaaa
    80941 tttcaaggtt attagaggat agggaaattc gaacgaatgc atctggttgc gcacgtgtag
    81001 taaagcgtct ggaatgataa agtcggatac cgttagcaag aaagtcattc tcaattatct
    81061 tagggtcaat ctcaggatca actggaagaa ttcgatagta agggacacga ttcgttggtt
    81121 tttctacttt gaaaagagaa tcaaaaagct gattggctct ttttgtaaga cttaatttag
    81181 tttctaagat cctatttgct tcatttgaat ggaggatttg agtgatgact tccacatcta
    81241 atccagaagt tttcacattt atattaaaaa ttgcttgttc tatcttgctt tggacatgta
    81301 ctggaactac aagataagca actcgcaatc cagaacaaat aaattttgtc attccagcta
    81361 agtagattgt ttggttaggt aataaatttt ggaaaggagg aatgatcgta tgttgatagt
    81421 aagttgttaa aaatgaatgg atatcatctt caataaccca tagaccttct ttttcaatca
    81481 cttcggctaa ttgctctcgt cttttgtgag agatttgaaa ccctatagga ttattacaag
    81541 aaggcataag aaagacacca tgaatcttct tttttctaca ttcctgaatc aatatatcag
    81601 gtcgcattcc ttgctcgtca aaatcaattg gaacgatctc taaatgatat aactgagcca
    81661 attcaatgaa attagcgtat gtatatcggt ctgttgctat tctatcacct ggagagaaaa
    81721 gtgcagaaag tgtgatagcc aatccatttt gaacaccgga aacaatagat agagattcta
    81781 aggacggaat gactccttga gtttttaacc aatttgctgc agtagtcaat tgaaaatttg
    81841 tgcctttggg atcttggtaa ttaagcaaac caacaagatt tgggttatta ctagttgatt
    81901 gaataaacgg gacaacgaat ttattacatt cttcaaaaga actaaccaga ccaaaatcaa
    81961 tgatatgttc ggttacttca ttggtagaga tggtgatgga ctcaaagaca ttgggagaaa
    82021 taaatgtgcc acttccaata ttcgtataca gcaaaccttt ctcaattcca tatttataag
    82081 ccttgccaac ggtagtaaaa tttaaatcta aataatcagc tagctctctt tgggagggta
    82141 actgagtgtt tttctgtaat ttattcttta aaatatcttg ttctaattgt tgaatcaacg
    82201 atcgataata aggacgcttc aatttttgtt tgtctggtcg ccaagttaac gggtaattgt
    82261 cataagaatt aataggcatt ttctccactc cttaaaattg tataccatac aattttacca
    82321 ttgattgtat tgattttaga agttaatctt ttgtgaggag ggaattgtct atgaaaatta
    82381 ttaattttga ggaagtagta gcttctttta gttttgaaga agcgattcaa gtaatgaaaa
    82441 aatgtttttt tgattatgaa agtggtaaaa tcagccaaaa tcctcgattg gtggaaattt
    82501 tacctgacgg aaaaggcaaa aatatgtttg cgatgatgcc tgcttatttg ggggagaaca
    82561 gatattttgg cacaaaagtc attaccgctt ttccggataa tcatcagtat catttacctt
    82621 ctcatttagg agagattttc ttgtttgatg ctcaaaacgg actacccaaa gcattgataa
    82681 acgcaaatgc agtcacctgg attcgaacag ctgctgtatc tgcgctggca acagattact
    82741 tagcaaatcc gcatgcagaa acacttgctt taattggagc tggtcaacaa gcattgtcgc
    82801 atttgactgc gatttctacc attcgtccca tcactacagt gtttgtttac gatattttag
    82861 aagaaagacg aaatactttt atcgctaaag ctaaaaaaca gtatcctaaa ataacgttta
    82921 taaatgcaat atcagtagaa gatgcagtac gtccagcgga aatcatttgt acgttgacct
    82981 ctagtaaaga ggcatttctt caaaaagagt gggtaaggga agacgcacat atcaatgctg
    83041 tgggcacatt tactcctgat acaagagaga taagtacatc gttgatggaa acttctcaaa
    83101 tctatgtaga tgattactca gctgccttaa cagaaagcgg ggacctgctt atagccatgg
    83161 cagaaggaga tttagaggaa tcttgtattg ttggtacatt aggcgaatta gtttctgaga
    83221 aaaaaacatt ttataaagga gaatcgaggc cgacgatttt cgacgcagtt ggtctagcta
    83281 ttgaagatct ttgttgtgca gaatatattt ataacaaatt agagaaaggg gctttaaaat
    83341 gaacttagat tattacgtag ttgatgcatt tgcagatgag gtgttcaaag gaaatccagc
    83401 agcggtttat gtgctagaag aatggctgcc agaaggtacg atgcaaaaaa ttgccattga
    83461 aaacaattta tctgaaacag catttacagt gaagaaaaac caagaatttg agcttagatg
    83521 gtttacgcca gatcgagaaa tcgatctttg tggtcacgcg acattagcaa cagcatttgt
    83581 tttatttaac tattacaaaa tacctgatga aacgattaaa ttttctactc aaagcggtaa
    83641 tctatttgtg acaagaatta aagattatta ttacatggat tttcctagta ttatgccgaa
    83701 aaaagtgccg atattgtctg aatatgaaga agcgattggg gctaagatta aagaagccta
    83761 cttagcacgt gatttatttt tcgtattaga agatgaaaaa acggtggcta aattgcagcc
    83821 agattttaca gctatcaaaa attttgaatt aggaatagga gtcatcgtga cagcagaaag
    83881 tgtgcaaaaa gactttgttt ctagaacctt ctttccaaaa ttaacaatca atgaagatcc
    83941 agtatgtgga tcagcacatt ctaatcttat tccttattgg gcagaaagaa tgaataaaac
    84001 aaaattgtca gcttatcaaa tgtcatcaag gggcggggat ctagaatgtg aattaaaaga
    84061 agatcgtgtg ataataggag gaaaagcagt tttgttttct aaaggtacct cgtttatttg
    84121 atttctttca aatgaattaa aaataaattg gtggagagtg gcaaccttat agctacaatg
    84181 gttgttaaaa aaagacgcaa actttttcaa tttaatgaaa agtttgcgtc tcattttaat
    84241 tattggtgtt tgttttttat tcaatcaaga gtaaaatgcc ccatactaac tatcctcgga
    84301 tgacttcgat tttataacca tcagggtcaa tgacaaagta gtaagaaggc gcagtgccag
    84361 gtaatccttt taagtcagta atctcaagac cggcagcttt atgttgctcg tgtaattttt
    84421 ctagatcatc agctgctata gcgatatgac catagccgtc tcctagatca tacgcaccat
    84481 gatcatagtt gtaagtcaac tctaattcat agtcatcccc aggaagtgtc aaataaacaa
    84541 gtgtaaattt gttttctgga aaatcacggc ggcggctttc ttcaaaacca aatgcctttt
    84601 gataaaattc gattgatgct tcaagatctt tcactcgaac acatgtgtga gccattttca
    84661 tagattcatc tctccttttc cttttactca atcataacaa aaagaagtaa ggaaatagtt
    84721 gatttgtgct tgttcatgag aaatttctca tgtaaaatgg atagaaaata aaactgttaa
    84781 ggtggaaact attcatggat aaaccaattt ttggtgaaaa aaagcaattt gctgattatc
    84841 aaacccgtta tgcagcatat attgtcatag aaagagatca gcagattgca gtaatcgagg
    84901 ctccaaatgg tgcttttttt cttcctggcg gggaaattga aggagaagag acgaaagaag
    84961 aagcgattgt ccgtgagctg atagaagaaa tgggaattgt ggcagaaatt tcttcttatc
    85021 tgggagaagc tgatgagtat ttttactcga attatcgtgc aacttattat tataatccag
    85081 gatatttctt tgttgctgat tcttggaagc gtataggaga accaactgaa aagaccaata
    85141 aaatttggtg ggtgagccct caagaagcgc ttgtgaaatt gaaacgtggt agccaccgat
    85201 gggcagtcga gagatggatc gaaaaaaata aaaactgaaa gaaagcgagt agatcagctt
    85261 tctctcagtt tttttattta ttacagtaca tattttttga ttgcttcagc tacaccgtgc
    85321 tcgtcgtttg atgaagtgat gacatttgct gcttctttga caagagaaac ggcatttccc
    85381 attgctactc ctagaccagc atattcaatc atggataagt cgttctcgtt atctccgata
    85441 gccatgattt catcttgatc aataccaagg tgctgtgcga gattcgcaac tgccgcacct
    85501 ttacttgctt ctttatttag tacttcgaag taatagggcg cacttttgac cgttgtgtat
    85561 ttatcacgga aagtttgcgg taaacgcgca attgctgcat ctaaaatttc tggttcgtcg
    85621 atcatcatca ttttgacgat gttcatgtct ggtgtcattt cttcaggtgt tcgatatttt
    85681 agcggcatct tgactaaact tgcttcgtgg atcgtataag cgctgatatc tcgattaggc
    85741 gtgtagatcg ctttgtcatc gatcgaatgg agatgactgc cgacacggcg tgccatcact
    85801 tcgatctcta ggaaatcttc atgtgtcagt ccgtgacggg cgatgatttt acctgatttc
    85861 gtttgttgta cgagtgcccc gttataagta ataacgtaat cattatcttg aaaaaggttc
    85921 aactcgttta actgttcctg gacacctggt aagggacggc cagtgcataa aacgatcgaa
    85981 acaccttttg caacagcagc ggcaatcgct tcttttactt cttttgttac ttctcttttc
    86041 tcatttaata aagtaccatc gatgtcgata gcgactagtt tgatagacat aatttcctcc
    86101 aatatatttt aatttatttc aatcaatgcg ccattacgga tatggctggc aaattcttga
    86161 taagtttcgt caaataaatc ataatgatca cgcaaggacg gatcaaccat ttcttttgga
    86221 aagaaaaatc gctcatctcc ttgttcttgt cccgctaatg cagcaacaag ctgactaacc
    86281 tgtgataatt ctatcaaagt tccgtcattt cgcaaaatct cgatttgtgt gcgatgtctg
    86341 ccttgttctg ggcgataaaa atcataaggt agatcgtagc tagaattcac agcagtgtaa
    86401 taaacaggat tatatccgac cttttctact aacaaagtga gttcttggac taattttgaa
    86461 tcccggttgc cagaaaaagt agcagatttc agtggtttac gattcaaaaa acgtttagct
    86521 aaatcattta aaataggatc agcagattca gaccattgag taaagtaagt gcccaagacc
    86581 ccatcatcaa gtttgaggta ttcttctaaa gtaaagcttc cgtcaagaaa tggcagaagt
    86641 aattgagaat ggagttcaaa actgctggca tcttcttgat acaactcgtg tgcgcgatga
    86701 agcagatgct ccaaaattac ttccatacca cgggaaacag gatggaagta cacttgcaca
    86761 tacatttgat atcggctaac gatataatct tccactgcat gcatgccact catggaaaaa
    86821 gcgatcccgc cttcataagg acgaatcaca cgtaatattc gggtaagatc aaatgttcca
    86881 tattctgttc cagtgaaata agcatcccga agcaaatagt ccattcgatc tgcatcgatc
    86941 tgactagaaa tcatttggac aacttgtggg ttggggtaag ttttttggat cacactagct
    87001 accttttcag gaaaaccttc ttctactcgg ttaagaatct gatacacttc tgtttctgga
    87061 gaagtgatga tctctacagt gatggcttca tgattcgtat ggaagatatg ttcaaatgta
    87121 tgagagtaag gaccatgacc gacatcatgc aacagtgccg cacataaagt caccagccgt
    87181 tcctgatcat cccagcctcc gttgcctatt ttttcttttg aaaaatttcg agaaaagata
    87241 tcgcagattc gtcttgaaat ctcataaacg cctaatgaat gagtaaaacg gctatgttct
    87301 gctccgtgaa aagtgaaaga agaagtgcct aattgtttaa tgcgtcgtag acgttggact
    87361 tctttcgaat tgatcaaatc taagattact tgatgctgga catggatata gttatggact
    87421 ggatcacgaa aaactttttc cataggcagc atttgatatt tataaggggt tgtcataatg
    87481 tagctccttt atgttattac gttgttccat tctctggatt tggttgttcc attgctccag
    87541 ctggatttct ttttttagcc agtcggtaga atcctgtaaa tcacttgcag aatacagctt
    87601 ttcaaaagct tttgcaaatg cttctttgac ttcttttaca aaaaggggtt ggtcaagcag
    87661 ttcttcaagt gttgccattg tagcaggatc cactgcagga tagccatttg taccaaagtc
    87721 ttcttttaaa gcagattgat aaaatcgctt catgacttgc ccgcgttttt cctgattacc
    87781 gttgacactt aagtacatca taacagaaat cccatttttg atccgacgct gagcgatacc
    87841 ggcaaatttt ttgccatgga tgcttaaatc ataagttcca ggacaataag aatgggtgat
    87901 ttcgaatgct tgtatcggtg cctttggaaa agcgtattta gtcaatagga gcatttgctc
    87961 gtaagcgtca tctatggtta ttttttttgt gtcactttgg gggaaaatca aagaaatatt
    88021 caaaattcct tcatctgata cgatccctaa tccacctgaa tttctgatca ctggagcgta
    88081 acctgcatct ttcagtgttt ggatcccgtc acttagaaaa ggagttcgaa catccttcat
    88141 acctaagatg actgtgcagt catattgcca gaaatgtaaa aagatttgct ggtgttcttt
    88201 agaatattcc gttaatatat ctgttaatgc aaaaggggaa aagtcgtttt tttgataaat
    88261 gtgctgatct agtcgaatcg cagggttcat tcaaccggct cctttgtata aattcatatt
    88321 ttctacaata ttatactcta aaatcaaaga gttgttttgg aaaaaaggtt ttctgtaaaa
    88381 atggacaagt tggttgacaa aacaaaagaa actaggaaca atgtagctat gagaagtaaa
    88441 ggagaatgaa taatggaatt atcacaagga acaccgattt caatcaaatt gcgtacaaaa
    88501 gtaaaacagc aaggggaagt gcaagatttt tattttgatt tgaaagggca aatggtgaca
    88561 attggcgata cgctgtacat acgttataaa gagattcagg aggagacggg cgatgagatt
    88621 cctgtaacga tcaaattagt tccagatggt catgtacagc tgatccgtgc aggagaaatg
    88681 cggatgcgtt tgaaatttgg ctataaagaa cggttagaaa catcctatcg aacaccatac
    88741 ggtatgatcc agattgctac ttttacgaaa gaactgcatg ttagtttgaa agaccgtccc
    88801 acaggaggga aggttcgaat cgattatgat ctgttcatgg gaccggaaaa aatcggcgaa
    88861 tattatttga ccttggattt tacagcgtaa atataaaaga aaagtttgat tttttgtgtc
    88921 tgattttgta tgataaggag tagactgtga aaggacgtgt cctgattgga aattagtgta
    88981 tttgaaggtg caaacaaaag cgaattatca atgatcgaag tagcacacgc gatcttagaa
    89041 caacgtggcg atgtcatgga tttttctgat ttagctaacc agatccaaaa ctatcttggg
    89101 aaatcagaca gtgaaattcg tgattcactc gcacaatttt atactgactt gaatattgac
    89161 ggcagcttta tctcattagg ggataatcgt tggggcttgc gttcatggta tgctatcgat
    89221 tcgatcgatg aagaagtaaa ccatggaatg gacgaagagg atgaagatac tccacgtcgc
    89281 cgtaaacgca agaaagtcaa cgcctttatc aatgatgatg aagacgcgat cgattacaat
    89341 gacgatgacc cagaagatac agatctgaca gaagaagatg acgatgatct gtttgatgac
    89401 gatgatgatg aagatgaaga aatcgctgct tataattctg acttgcaaga aatcggagca
    89461 gatgacccga cagatgatga agaagacttg ccaggaaata tcgaagaaga tttaagtatc
    89521 atagacgaag acgatgatga tgaagattat gaagaggaag aattttctga ctctgaaaaa
    89581 gaataaacat tattttctta cgagaggttg tgacagagac gatcagccta tcagaataag
    89641 gaggtgtgac acgatttttg tcacaccttc ttttttgtat ataaaaatcc caagtaaata
    89701 cataaaaaat aaaaaaattg aaacttttag cgcaccttgt acgtcatatt aagtgaggca
    89761 gaaaggagtg gagaatgatt tttactggat ataagaaaaa acggcagatc gaaaaatacc
    89821 gtcacctgct gaatggactc atcgaaactg attatcaaaa aatgttccgt atcacgatga
    89881 attacgtaca tgataaagaa gaggccttag atgtgatgca agatagtttt cataaagccc
    89941 tgaactattt tgaaaaagaa aaagagatcg agcattttag tgcatggttt tatcggatat
    90001 tgatccgcac ggcattagat agttggcgca gacaaaaaag gacgcctgtg gacttatttg
    90061 aaattcaaga tatcccccaa cagttacctt tagaaacttc cgttgcagag ctccatatga
    90121 ttttagataa aatagacagt ccggaaaaag agattctgat cctctacttt tttgaaggat
    90181 ttcgtttgaa agaaattgcg actatcttgg atatgaatga aaacacagtt aaaacgaaaa
    90241 tgtaccgctc attgaatgct ttacgtcaaa tcctagaatg aaggagagaa gagtgccatg
    90301 tattcccaaa aagaaaattt aaaaaaacta aagaaaactt ataaagaaca agcaattccc
    90361 aaagggctta aagaggagat ccgccagcgt tttattatcg aagagcaatc atttataaaa
    90421 gcaaagcgga gaaagagacg tctccaaggg ttcggagtat ctttggctat cgtaatgatt
    90481 acaacaagta gccttctttt taatagtcaa gttcgaagct ttgcagaaga tttacccatc
    90541 ttaggatcag tcattgaatt gatcttaggc gaacgcttta ctgatcgatc tgaaaaaatc
    90601 gatattcagg taccgaagat caatacacaa aatgagaaag aaaataaaac aattcatgga
    90661 ttaaatcaaa aatactttcg cgaaggacaa gcagattttg aaaaagctga aaaagaatat
    90721 ggaaattttg aaacggatca ttaccaagtt ttgggagatt atcagaaaat cgtagacgat
    90781 aaccggtttc tcgtgattga aaggcagatc acccaaacag cagcagatag ccatgttgaa
    90841 aaaagatacg acacaatcga caagaaaaac agtgtccagc tctcacttcc acttttattc
    90901 aaagatgaca cctatctatc tgttttgaca aaagaagtca aacggcagat ggccgaacaa
    90961 gtcaaggaag atccatctaa gtactattgg actgagcaag atattcaaga agggacgata
    91021 gaaaaaccaa cacttgttac gcctacacga agtttttatt tgaacaaaga gcatcaatta
    91081 gttttgactt tttctcaata cgaaattgct cctggttata tgggtacacc agaatttgtc
    91141 attcctaagt ccgtgacaaa aacgattttg gcatcggaag attatttgga tcattagacg
    91201 agaagtagtt gcgactagca gtttcaattt tcaagtaagt acaagtaaat aataagaaga
    91261 gaaaaagaga aagaagagat atagtgaaaa gaaattattt agttatcagt attattgctt
    91321 tatccgtgct tttgtttttc gaaattactt cggtggcctc cttgatcacc gaagtaaaag
    91381 gacaaacaca ctcttcggag cattcgtcac aatctttcaa acaatcagaa caatcaacca
    91441 ttaaaagcca atcaactgaa acagctaacg tcaaagaagc cattcaagaa tcagcggaaa
    91501 aggtacaaag tcagtcatca caatcaacac aagacagtac aaaaacgagc cgagatccgg
    91561 ctgtcaaaag cgtcgcaatc agctttgatg atggaccagg agcgaccaca acaccgcagc
    91621 ttctgcgaat cttaaaagaa aaaaacgtgc atgccacttt tttcgtctta ggagaaaata
    91681 cggcgcagca tcctgaaatc gtgaagcaga cagctgaagc agggcacgag attggcaatc
    91741 acacatacga tcatcagaat ctggccactc tttctgccca gtcgatgacg gaggaagtga
    91801 cgaaagcaga cactgagatc aaaaaagtca ctggcaaaac ccccactttt gttcgtccgc
    91861 cctatggttc tgtcacgaat gtaggagcaa cgatcatcca gcgaccgatc atcgaatggt
    91921 ctgttgattc agaagattgg aagacaagaa atcctgattt gattttgcag aagatccaag
    91981 caacagtata cgatggggca attattttat tccatgatat ctatcctgaa acgattcgtg
    92041 ccgttcctca agtgatcgat tatctgaaag agcaagggta tcgcatcacg acagttgggg
    92101 atttattagg gcatccaacg gctgtcgaga actattatgg cagaaacgat catcggccag
    92161 ttcagtaagt gagacaagta tctttaataa ataacacatt ttaataagta gttgaacaca
    92221 taactacctt acttgcaaag gcttaacaat atctatacag gtacaacaaa aaactgtcca
    92281 ccaattttct ttggcggaca gttttcactt aaaaataaag aagcaactat tcgtaaatta
    92341 tgctaaaata gcagtagaac gcgtcctgag ggaatcgaac ccccgtctca agaaccggaa
    92401 tcttacgtga tatccactac actaaggacg caagcactgg gataattgta actaaacaga
    92461 taaaaaatta caaggggatt ggacaaaaaa atgaaatttg agcaaaattt ttcacaaaaa
    92521 cagcagcaga cacagaaact agccatgacg caacagttgc aacagtccat ccaagtttta
    92581 caatataaca gtgaggagct gttggcattc gttgagaatc aagcaatgga aaatccattg
    92641 gtggaagttg ttgagccgga atggcagcca gattacataa aagcttcttc atcttcttat
    92701 gaaggagaag agacaaatta cctaaatcag attcctgata caaaagggtc tttatttgat
    92761 tcattgatcg aacaagtcca tttgaattac cgagatactt ttttgaggaa aatcgttctt
    92821 tatcttgtag aatacatcga tttgaacgga tttttgacga ttagtttaga agaagccgga
    92881 aaagagattg gagctacgcc tatccaaatg ctcgatgcgt tgactctgat tcagcaatta
    92941 gaaccagctg gagtaggtgc acgtagtttg caagaatgtc tcatgcttca aacagaacga
    93001 gatgattatg cgccggaatt agcttatatc gtgttggaag aatgttttga ggaactggtg
    93061 gagcgaaaat ggaaagaaat cgcacaacgt ttttctgttg atctacatgc tgttcagcag
    93121 atattcgact atttacaaac gttgagtcca agccctggcc ggattttcga ccgtagcagc
    93181 gaattgtaca ttattcctga tgtccgggta ttagtggacg acgataaaaa tgtacaagtt
    93241 atctcaaacc gaaaaaatca gccaaatata cgctttcaag agagttactt caaacaaatg
    93301 tcacaacaag cagataaaga aactgaaaat tatttaaaag aacggaaaca ggaattcgaa
    93361 tggttgaaga aaacgatcct acaacgtggg gatacaattt tgcgggttgc tcaagtcatt
    93421 gtttcccggc aaaaagcttt ctttatcgac aaggaacgtc caatcaagcc tcttacgtta
    93481 aaggaagttg caactgagat agatgtgcat gaatccacgg tcagtcgtgc agtcaacggg
    93541 aaatatttgg aaacagactt cggtgtattt gaattaaaaa aatttttcac tacacgaatt
    93601 cctacgaata gtacagaaca gacagaagac ctttcagcag atacagcgaa gaaaaagctg
    93661 caggaattag tcgatcaaga agacaaaaac aagccgttgt ctgaccagaa attggttgaa
    93721 ttgctgaaaa aagatgagat agcgatctca agacgaacag tagcaaaata tcgtgattta
    93781 ttaggaatcc cgagttcatc aaaaagaaaa cgttatgata actaatcagt caaaagacta
    93841 gaaaaagtat ttcacttttt ctagtctttt tagttgaaaa acgagagcaa aactgttaga
    93901 cttacagtcg tgaggttgag atttcccttt attgatgtga aattcgaata gttaatttct
    93961 ttttttatcg tatatgggtc gttttaagtc tacattggac gtaaagtgtc caactaagga
    94021 gatcgctatg ctggatgaaa taaaaatgat tgaatctgtt gcaccagata ttatcgaagt
    94081 gttgcaagaa cgctataaaa ttttacgaaa tatctattgg atgcagccga ttgggcgtcg
    94141 aagtttatcg gaaagtatgg ggatcacaga acgagtctta cgaacagaaa cagacctttt
    94201 gaaaaatctg aatttgatcg acacctcaaa aagcggtatg acgctgacaa ctaagggcga
    94261 agaagtttat caaagccttg aaaacttcat ggatcagctt ttaggtacgc atcaaaccga
    94321 acaacagttg gcagaatatt ttggtaacca acgctgtatc gttgtttcag gaaacagcga
    94381 agagcagacc aaagtggctg atgcattcgg cgaagcgctg agcgaagcct tagaccgact
    94441 acttccagaa ggcgagaata tcatcgctgt gatgggagga actactatgg ctgtggtagc
    94501 cgaacaattg tctaatctgg aaaataagaa acggcataac ctgtttgtcc ctgcaagagg
    94561 cgggattggt gaagcgataa ctgtacaggc aaattctgtc agtgcaagaa tggctgctaa
    94621 agcaaacggt aaccaccgcg cactttatgt tccggaacaa ttaagtctgg caacttacaa
    94681 ttctttactc aatgagccat ctatccaaga agtcttaaac ttgattagtg aagcgaattg
    94741 tgttattcat agtattgggc gtgcattaca catggcagca cgtcgtaaga tgactgaaaa
    94801 agaattagtc atgctgaaac aagcaaatgc tgttgcggaa tcttttggct actttttcaa
    94861 tgaaaaaggt gaagtcgttt ataaggtccc tagaatcggc atagaattgc aagatttgga
    94921 aaaagtcccg atcatcatgg caatcgcggg cggaaaatca aaagctaaag caattcgagc
    94981 ttatatgaaa aatgcaccaa aacaaacgtg gctcatcact gatgaagctg ctgcaaatga
    95041 gattttaaaa ggggtaaccc tttaaaataa atattttttt gattttcata aggaggaaat
    95101 cttaaatgac agttaaagta ggtattaatg gttttggacg tattggacgt ctagcattcc
    95161 gtcgtatcca agatgtagat ggaatcgaag tagtagcaat caacgacttg acagatgcta
    95221 aaatgttggc acacttgtta aaatacgaca caactcaagg acgtttcaac ggaacagttg
    95281 aagttcatga aggttcattc aacgtaaacg gaaaagaagt taaagtatta gctaaccgca
    95341 acccagaaga attaccatgg ggcgaactag gcgtagatat cgttctagaa tgtactggtt
    95401 tcttcacttc taaatcagca gctgaaaaac atttaacagc tggtgctaaa cgcgttgtta
    95461 tctctgctcc tggcggaaac gatgttccaa caatcgttta taacacaaac cacgaaacat
    95521 taactggtaa agaaacagtt atctcaggtg cttcatgtac tactaactgt ttagctccta
    95581 tggctaaaac attgaacgac aaatttggtg ttgttgaagg attaatgaca actatccacg
    95641 cttacacagg tgaccaaatg actctagacg gacctcatcc taaaggtgac ttccgccgtg
    95701 cacgcgctgc tgctgcaaac atcgttccta actcaacagg tgctgctaaa gctatcggtt
    95761 tagtaattcc cgaattgaac ggtaaattag acggagctgc tcaacgtgtt cctgtaccaa
    95821 caggttcatt aacagaatta gtaacagttc ttgaaaaaga agtaactgtt gacgaaatca
    95881 atgcagcaat gaaagaagct tcaaacgaat cttacggata caacacagac gaaatcgttt
    95941 cttcagatat cgttggtatg acttacggtt cattatttga tgctacacaa actaaagtaa
    96001 tgacagttgg cgacaaacaa ttagttaaaa ctgttgcttg gtacgacaac gaaatgtcat
    96061 acactgcaca attagtacgt actttagaat acttcgctaa cttataagat agacaaacgt
    96121 acaagtgtaa attatagaca tgtacattta aaagcgggga agcaatcgcg cttcttccgc
    96181 tttttttgat aataagttta ttcaggagga aataaaatgg ctaagaaaac agtgaaagat
    96241 atcgatttaa aagacaaaaa agttcttgtc cgtgttgact tcaacgttcc tttgaaagac
    96301 ggcgtgatca ctgacgacac tcgtatcaaa gcagcattgc caacaatcaa ctacgttcta
    96361 gaacaaggcg gaaaagcaat ccttttctct caccttggac gtgtaaaaac agaagaagat
    96421 aaagaaggaa aatctttagc tccagttgca aaacgtctag gcgaattatt aggtaaagaa
    96481 gtaacattcg tacctgaaac tcgcggagaa caattagaag aagcaatccg caacatgaat
    96541 gacggcgacg ttgtcgtatt cgaaaataca cgatttgaag atattgacgg taaaaaagaa
    96601 agcaaaaatg atacagaact aggtaaatac tgggcttcat taggcgatgt atttgttaac
    96661 gatgctttcg gtacagctca ccgtgcacat gcttctaacg taggtatcgc ttcaactggt
    96721 atcccaacag ttgctggatt cttgatggaa aaagaaatca agttcatcgg tgaagcagta
    96781 gaagaaccaa aacgaccaat gattgcaatc cttggtggcg caaaagtttc tgataaaatc
    96841 ggcgtaatcg aaaacttgat tcctaaagca gataaaatct tgatcggtgg cggaatgact
    96901 tacacattct acgaagcaaa aggaatcaag atcggtaact ctctagtaga agctgataaa
    96961 gtggaactag caaaagaatt aatcgaaaaa gcaggcgaca aacttgtctt gccaatcgac
    97021 aatgtctgtg caccagaatt ttcaaatgat gttgaaacac aagtaatcga aggagacatt
    97081 cctgatggtt tgatggcttt agacatcggc ccagcatcag taaaattatt tgctgataca
    97141 ttacaaggtg caaaaacagt tgtttggaac ggacctatgg gtgtatttga aatgagtaac
    97201 tttgctaaag gtacaatcgg tgtttgtgaa gcaatcgcta acttagaagg cgcaacaaca
    97261 atcatcggtg gcggagactc agccgcagca gcagaacaat taggatttgc tgacaaattc
    97321 acacacatct caacaggtgg cggcgcaagc ttggaattgc ttgaaggtaa agaattacca
    97381 ggactagcag caatcaacga taaataaacg accaagtttg ctcaattctg acgagtaatc
    97441 gaacaaaagg tgaagggagt tttcatgact ccctagccat ttttcaataa attaaggagt
    97501 gtgttcctca atgcgtaaac ctattatcgc aggtaactgg aaaatgaaca aaactgcatc
    97561 agaagcaaaa gaatttgctg aagcagtaaa aaacaaaatc ccttcaaatg acaaagttga
    97621 ttcagtcatc ggatctcctg cattattctt acaagaatta atgacatcag ctgaaggtac
    97681 agaactaaaa atctcagcac aaaactgcta ctgggaaaac tcaggtgcgt tcactggtga
    97741 aacttcacca gcagctcttg ctgatctagg tgttcattat gtgatcatcg gacattcaga
    97801 acgtcgtgaa tatttccatg aaacagacga agacatcaat aaaaaagcga aagctatctt
    97861 tgcaaatggt atgacaccaa tcctatgctg cggcgaatct ttagaaacct atgaagcagg
    97921 caaaactgct gaatggatcg aaggacaaat tacagctggt ttagctgatc tttcagctga
    97981 acaggtgtca aacatggtta ttgcttatga accaatctgg gcaatcggta ctggtaaatc
    98041 agctgacgca caaatcgctg acgaaatttg tggagttgta cgtcaaacag ttgaaaaact
    98101 ttatggaaaa gaagtatcag aagcagttcg tatccaatac ggcggttctg taaaaccaga
    98161 aaatattgct gaatacatgg caaaagaaaa tgttgacggt gctttagtcg gtggcgcaag
    98221 cttgcaagca gattcattct tgtcattgtt agacgctgta aaataattgt tgaaaatttg
    98281 cgaaaaatgc aagaaatgtt tgcactaatg agcaaaatta actaaaatcg tatatgaggg
    98341 aaatccctta ggaaaaaaca aactcaaagg agagacaaaa catgtcaatt attactgatg
    98401 tttacgctcg cgagatctta gactcacgtg gtaacccaac aatcgaagta gaagtataca
    98461 cagaaagcgg agcttttggc cgcggaatgg ttccttcagg tgcttcaact ggtgaatacg
    98521 aagcagttga attacgtgac ggagacaaag ctcgttatgg cggtaaaggt gtaactaaag
    98581 ctgtcgacaa cgtaaacaac atcattgctg aagcaatcat tggctacgat gttcgtgacc
    98641 aaatggctat cgacaaagct atgatcgctt tagacggaac tcctaacaaa ggtaaattag
    98701 gtgcgaacgc tattttaggt gtttctatcg ctgttgcacg tgcagctgct gactacctag
    98761 aagtaccttt ataccactac ctaggcggat tcaacacaaa agtattgcca acaccaatga
    98821 tgaacatcat caacggcgga tcacatgctg ataactcaat cgacttccaa gaattcatga
    98881 tcatgcctgt tggcgctcca acattcaaag aagctctacg tatgggtgct gaagtattcc
    98941 acgcattagc ttcaatcttg aaagctcgcg gattagcaac ttctgttggt gacgaaggtg
    99001 gatttgctcc aaaccttggt tcaaacgaag aaggttttga agtaatcatc gaagcaatcg
    99061 aaaaagctgg ctatgtacct ggtaaagacg ttgttcttgc tatggatgct gcttcttcag
    99121 aattctacga caaagaaaaa ggtgtttacg tactagctga ctcaggcgaa ggcgaaaaaa
    99181 caactgacga aatgatcaaa ttctacgaag aattagtttc taaatatcca atcatctcaa
    99241 tcgaagatgg attagacgaa aacgactggg acggattcaa gaaattaact gacgtattag
    99301 gcgacaaagt tcaattagtt ggtgacgact tgttcgtaac aaacactcaa aaattatctg
    99361 aaggtatcga aaaaggaatt gctaactcaa tccttatcaa agtgaaccaa atcggtacat
    99421 taacagaaac tttcgaagct atcgaaatgg ctaaagaagc tggctacaca gcagttgtat
    99481 ctcaccgttc tggtgaaaca gaagattcaa caatctctga tatcgctgtt gcaacaaacg
    99541 ctggccaaat caaaactggt tctctatcac gtactgaccg tattgctaaa tacaaccaat
    99601 tactacgtat cgaagaccaa cttggtgaag ttgcagaata caaaggtttg aaatctttct
    99661 acaacttaaa aaacaaataa ttcttttcta atgaagatac atgatcgact attgaaagat
    99721 agtcgagtat gatcacttag ttaagtaatc gaactctcta cttgctgaaa tatcagcagg
    99781 tagagagttt ttttgcaact agcttctgta tatgatgttt acaaagaatg gtacaagaaa
    99841 agatcatcct tgaaaaagga aagctaacaa taactagcat catataagag cttttaagga
    99901 tagaacagta gaataggaat ctatgggcaa gtcctctcgt ataa
//
LOCUS       DAPBBV010000005        94607 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.005, whole genome shotgun sequence.
ACCESSION   DAPBBV010000005 DAPBBV010000000
VERSION     DAPBBV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 94607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.005"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            169..1227
                     /locus_tag="RD486_000469"
     CDS             169..1227
                     /locus_tag="RD486_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDT7662231.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1231..2265
                     /locus_tag="RD486_000470"
     CDS             1231..2265
                     /locus_tag="RD486_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HDT7662232.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2367..3083)
                     /locus_tag="RD486_000471"
     CDS             complement(2367..3083)
                     /locus_tag="RD486_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7662233.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3052..3837)
                     /locus_tag="RD486_000472"
     CDS             complement(3052..3837)
                     /locus_tag="RD486_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HDT7662234.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3828..4577)
                     /locus_tag="RD486_000473"
     CDS             complement(3828..4577)
                     /locus_tag="RD486_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7662235.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4875..5399
                     /locus_tag="RD486_000474"
     CDS             4875..5399
                     /locus_tag="RD486_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDT7662236.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5415..6914
                     /locus_tag="RD486_000475"
     CDS             5415..6914
                     /locus_tag="RD486_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDT7662237.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(7002..7604)
                     /locus_tag="RD486_000476"
     CDS             complement(7002..7604)
                     /locus_tag="RD486_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7662238.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7708..8664
                     /locus_tag="RD486_000477"
     CDS             7708..8664
                     /locus_tag="RD486_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDT7662239.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8969..9925)
                     /locus_tag="RD486_000478"
     CDS             complement(8969..9925)
                     /locus_tag="RD486_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7662240.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10099..10659
                     /locus_tag="RD486_000479"
     CDS             10099..10659
                     /locus_tag="RD486_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662241.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10652..11476
                     /locus_tag="RD486_000480"
     CDS             10652..11476
                     /locus_tag="RD486_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDT7662242.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11486..12103
                     /locus_tag="RD486_000481"
     CDS             11486..12103
                     /locus_tag="RD486_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7662243.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12121..12804
                     /locus_tag="RD486_000482"
     CDS             12121..12804
                     /locus_tag="RD486_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDT7662244.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13487..14770
                     /locus_tag="RD486_000483"
     CDS             13487..14770
                     /locus_tag="RD486_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7662245.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14786..15673
                     /locus_tag="RD486_000484"
     CDS             14786..15673
                     /locus_tag="RD486_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7662246.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15690..16526
                     /locus_tag="RD486_000485"
     CDS             15690..16526
                     /locus_tag="RD486_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7662247.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16529..17152
                     /locus_tag="RD486_000486"
     CDS             16529..17152
                     /locus_tag="RD486_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662248.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17149..18441
                     /locus_tag="RD486_000487"
     CDS             17149..18441
                     /locus_tag="RD486_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7662249.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18800..18897
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            19013..19594
                     /locus_tag="RD486_000488"
     CDS             19013..19594
                     /locus_tag="RD486_000488"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDT7662250.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19597..20904
                     /locus_tag="RD486_000489"
     CDS             19597..20904
                     /locus_tag="RD486_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDT7662251.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21320..21808
                     /gene="purE"
                     /locus_tag="RD486_000490"
     CDS             21320..21808
                     /gene="purE"
                     /locus_tag="RD486_000490"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDT7662252.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21801..22925
                     /gene="purK"
                     /locus_tag="RD486_000491"
     CDS             21801..22925
                     /gene="purK"
                     /locus_tag="RD486_000491"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDT7662253.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22938..24233
                     /gene="purB"
                     /locus_tag="RD486_000492"
     CDS             22938..24233
                     /gene="purB"
                     /locus_tag="RD486_000492"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDT7662254.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24413..24790)
                     /locus_tag="RD486_000493"
     CDS             complement(24413..24790)
                     /locus_tag="RD486_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662255.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            25046..25774
                     /locus_tag="RD486_000494"
     CDS             25046..25774
                     /locus_tag="RD486_000494"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDT7662256.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25774..26028
                     /gene="purS"
                     /locus_tag="RD486_000495"
     CDS             25774..26028
                     /gene="purS"
                     /locus_tag="RD486_000495"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HDT7662257.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            26030..26701
                     /gene="purQ"
                     /locus_tag="RD486_000496"
     CDS             26030..26701
                     /gene="purQ"
                     /locus_tag="RD486_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HDT7662258.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26702..28924
                     /gene="purL"
                     /locus_tag="RD486_000497"
     CDS             26702..28924
                     /gene="purL"
                     /locus_tag="RD486_000497"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HDT7662259.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28909..30348
                     /locus_tag="RD486_000498"
     CDS             28909..30348
                     /locus_tag="RD486_000498"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDT7662260.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30371..31423
                     /locus_tag="RD486_000499"
     CDS             30371..31423
                     /locus_tag="RD486_000499"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDT7662261.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            31420..31998
                     /gene="purN"
                     /locus_tag="RD486_000500"
     CDS             31420..31998
                     /gene="purN"
                     /locus_tag="RD486_000500"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDT7662262.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            31995..33530
                     /gene="purH"
                     /locus_tag="RD486_000501"
     CDS             31995..33530
                     /gene="purH"
                     /locus_tag="RD486_000501"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDT7662263.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33546..34820
                     /gene="purD"
                     /locus_tag="RD486_000502"
     CDS             33546..34820
                     /gene="purD"
                     /locus_tag="RD486_000502"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDT7662264.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34942..35856
                     /locus_tag="RD486_000503"
     CDS             34942..35856
                     /locus_tag="RD486_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7662265.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(35989..37554)
                     /locus_tag="RD486_000504"
     CDS             complement(35989..37554)
                     /locus_tag="RD486_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7662266.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37547..38998)
                     /locus_tag="RD486_000505"
     CDS             complement(37547..38998)
                     /locus_tag="RD486_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7662267.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(39012..40028)
                     /locus_tag="RD486_000506"
     CDS             complement(39012..40028)
                     /locus_tag="RD486_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7662268.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            40248..41336
                     /locus_tag="RD486_000507"
     CDS             40248..41336
                     /locus_tag="RD486_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HDT7662269.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41390..42916
                     /locus_tag="RD486_000508"
     CDS             41390..42916
                     /locus_tag="RD486_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDT7662270.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42918..44123
                     /locus_tag="RD486_000509"
     CDS             42918..44123
                     /locus_tag="RD486_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7662271.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44380..45357
                     /gene="guaC"
                     /locus_tag="RD486_000510"
     CDS             44380..45357
                     /gene="guaC"
                     /locus_tag="RD486_000510"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDT7662272.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45621..47045
                     /locus_tag="RD486_000511"
     CDS             45621..47045
                     /locus_tag="RD486_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDT7662273.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            47506..48615
                     /gene="pdhA"
                     /locus_tag="RD486_000512"
     CDS             47506..48615
                     /gene="pdhA"
                     /locus_tag="RD486_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HDT7662274.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48618..49595
                     /locus_tag="RD486_000513"
     CDS             48618..49595
                     /locus_tag="RD486_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDT7662275.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            49620..51263
                     /locus_tag="RD486_000514"
     CDS             49620..51263
                     /locus_tag="RD486_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HDT7662276.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            51271..52677
                     /gene="lpdA"
                     /locus_tag="RD486_000515"
     CDS             51271..52677
                     /gene="lpdA"
                     /locus_tag="RD486_000515"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDT7662277.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            52839..53114
                     /locus_tag="RD486_000516"
     CDS             52839..53114
                     /locus_tag="RD486_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HDT7662278.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            53120..53887
                     /locus_tag="RD486_000517"
     CDS             53120..53887
                     /locus_tag="RD486_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HDT7662279.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            54055..55884
                     /gene="typA"
                     /locus_tag="RD486_000518"
     CDS             54055..55884
                     /gene="typA"
                     /locus_tag="RD486_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDT7662280.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            56145..57917
                     /gene="recQ"
                     /locus_tag="RD486_000519"
     CDS             56145..57917
                     /gene="recQ"
                     /locus_tag="RD486_000519"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDT7662281.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLRKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            58031..58333
                     /locus_tag="RD486_000520"
     CDS             58031..58333
                     /locus_tag="RD486_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HDT7662282.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            58336..59499
                     /locus_tag="RD486_000521"
     CDS             58336..59499
                     /locus_tag="RD486_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7662283.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            59525..62953
                     /locus_tag="RD486_000522"
     CDS             59525..62953
                     /locus_tag="RD486_000522"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDT7662284.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            62974..64098
                     /locus_tag="RD486_000523"
     CDS             62974..64098
                     /locus_tag="RD486_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662285.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            64088..64525
                     /locus_tag="RD486_000524"
     CDS             64088..64525
                     /locus_tag="RD486_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7662286.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            64509..64847
                     /locus_tag="RD486_000525"
     CDS             64509..64847
                     /locus_tag="RD486_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HDT7662287.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            64966..65526
                     /gene="rsmD"
                     /locus_tag="RD486_000526"
     CDS             64966..65526
                     /gene="rsmD"
                     /locus_tag="RD486_000526"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDT7662288.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            65523..66014
                     /gene="coaD"
                     /locus_tag="RD486_000527"
     CDS             65523..66014
                     /gene="coaD"
                     /locus_tag="RD486_000527"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDT7662289.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            66004..67047
                     /locus_tag="RD486_000528"
     CDS             66004..67047
                     /locus_tag="RD486_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HDT7662290.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            67206..67934
                     /locus_tag="RD486_000529"
     CDS             67206..67934
                     /locus_tag="RD486_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDT7662291.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            68050..68295
                     /locus_tag="RD486_000530"
     CDS             68050..68295
                     /locus_tag="RD486_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7662292.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            68292..68510
                     /locus_tag="RD486_000531"
     CDS             68292..68510
                     /locus_tag="RD486_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDT7662293.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            68646..69185
                     /locus_tag="RD486_000532"
     CDS             68646..69185
                     /locus_tag="RD486_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HDT7662294.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            69178..71451
                     /locus_tag="RD486_000533"
     CDS             69178..71451
                     /locus_tag="RD486_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HDT7662295.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            71489..72535
                     /gene="holA"
                     /locus_tag="RD486_000534"
     CDS             71489..72535
                     /gene="holA"
                     /locus_tag="RD486_000534"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDT7662296.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(72624..72878)
                     /locus_tag="RD486_000535"
     CDS             complement(72624..72878)
                     /locus_tag="RD486_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDT7662297.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(73278..73547)
                     /locus_tag="RD486_000536"
     CDS             complement(73278..73547)
                     /locus_tag="RD486_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662298.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(74017..74472)
                     /locus_tag="RD486_000537"
     CDS             complement(74017..74472)
                     /locus_tag="RD486_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HDT7662299.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(74610..76538)
                     /locus_tag="RD486_000538"
     CDS             complement(74610..76538)
                     /locus_tag="RD486_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDT7662300.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(76735..77568)
                     /locus_tag="RD486_000539"
     CDS             complement(76735..77568)
                     /locus_tag="RD486_000539"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDT7662301.1"
                     /translation="MFFANIIKAVILGIIEGITEWVPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(77760..78464)
                     /locus_tag="RD486_000540"
     CDS             complement(77760..78464)
                     /locus_tag="RD486_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7662302.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(78487..79113)
                     /locus_tag="RD486_000541"
     CDS             complement(78487..79113)
                     /locus_tag="RD486_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7662303.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            79439..81814
                     /locus_tag="RD486_000542"
     CDS             79439..81814
                     /locus_tag="RD486_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HDT7662304.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(81838..82329)
                     /locus_tag="RD486_000543"
     CDS             complement(81838..82329)
                     /locus_tag="RD486_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HDT7662305.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            82516..83436
                     /locus_tag="RD486_000544"
     CDS             82516..83436
                     /locus_tag="RD486_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7662306.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            83590..83934
                     /locus_tag="RD486_000545"
     CDS             83590..83934
                     /locus_tag="RD486_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HDT7662307.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(84124..84624)
                     /locus_tag="RD486_000546"
     CDS             complement(84124..84624)
                     /locus_tag="RD486_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662308.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            85152..85235
                     /locus_tag="RD486_000547"
     tRNA            85152..85235
                     /locus_tag="RD486_000547"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:85186..85188,aa:Leu,seq:cag)
     gene            complement(85559..86197)
                     /locus_tag="RD486_000548"
     CDS             complement(85559..86197)
                     /locus_tag="RD486_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7662309.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            86532..86966
                     /locus_tag="RD486_000549"
     CDS             86532..86966
                     /locus_tag="RD486_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7662310.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            86989..87309
                     /locus_tag="RD486_000550"
     CDS             86989..87309
                     /locus_tag="RD486_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662311.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            87450..87641
                     /locus_tag="RD486_000551"
     CDS             87450..87641
                     /locus_tag="RD486_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662312.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(87712..87969)
                     /locus_tag="RD486_000552"
     CDS             complement(87712..87969)
                     /locus_tag="RD486_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDT7662313.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            88127..88390
                     /locus_tag="RD486_000553"
     CDS             88127..88390
                     /locus_tag="RD486_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662314.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            88414..88602
                     /locus_tag="RD486_000554"
     CDS             88414..88602
                     /locus_tag="RD486_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662315.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(88685..88870)
                     /locus_tag="RD486_000555"
     CDS             complement(88685..88870)
                     /locus_tag="RD486_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662316.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            89085..89456
                     /locus_tag="RD486_000556"
     CDS             89085..89456
                     /locus_tag="RD486_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7662317.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(89606..89678)
                     /locus_tag="RD486_000557"
     tRNA            complement(89606..89678)
                     /locus_tag="RD486_000557"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89643..89645),aa:Gln,seq:ctg)
     gene            complement(89724..90152)
                     /locus_tag="RD486_000558"
     CDS             complement(89724..90152)
                     /locus_tag="RD486_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662318.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(90212..90970)
                     /locus_tag="RD486_000559"
     CDS             complement(90212..90970)
                     /locus_tag="RD486_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDT7662319.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            91265..91462
                     /locus_tag="RD486_000560"
     CDS             91265..91462
                     /locus_tag="RD486_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662320.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            91568..92050
                     /locus_tag="RD486_000561"
     CDS             91568..92050
                     /locus_tag="RD486_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662321.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(92108..92704)
                     /locus_tag="RD486_000562"
     CDS             complement(92108..92704)
                     /locus_tag="RD486_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7662322.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            93091..94557
                     /locus_tag="RD486_000563"
     CDS             93091..94557
                     /locus_tag="RD486_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDT7662323.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        30688 a        16252 c        20142 g        27525 t
ORIGIN      
        1 ttttttgtgt tctagtaaaa atcactttac ataagtttca aaagtttctt taatttccta
       61 ttgttcaata agtaacaatg taaagataaa attaaaaatg ttaatacgta ttagcaaaat
      121 aaaagctttt tttattgtga ataaatgaac ataattagga ggagaaagat gaacttattt
      181 gacatttttc gatcgacttt gacagatatg tcgattgtca gtgcaatcac ttcaacagtt
      241 tttattatat tattagggtt tgtttgtaga aaaaagggga ttttttctga atctgttgga
      301 aaaattctat cgaaagtcgt cttaacagtg gctttgccag cactggcatt tcgagctttc
      361 atgcaagata tcaatacaga attactgatg caaggaatca atgtcttgat ttggggatta
      421 gttatttata ttattcttat tctagtttca aaaccttttt tcttaagcta taaaggggat
      481 aagcaaacaa cgttgcgtgt cctgacgatc tttggttcta cgaccttttt cggaacgcct
      541 atcgtcagtg cgatttatgg tcctgtcggc gtgatgtatt cctcaatttt caatattggc
      601 taccgaatct ttttgtattc ttatggatac ataaaaatga gtggcttgaa gatggaagct
      661 aaaaatatca aagcgatgtt cgtcaatcca atcattatcg ctacttttgc cggccttttc
      721 atttggctgt tccaagggta tctgccacaa gtgtcagtta caggtgcaga aggagagata
      781 agccaagtag cgtttttgcg aattgaccag actgcaccgt ggctatttca gccgatggat
      841 tatttagctg gtttaagttc accattggcg tggctagcaa tcggcgcaac attaggtgaa
      901 gtaagcttca aaaaagctgc atctgaaaaa acttcatggt attacagtct agtcaaagtg
      961 gtatttgtac ctgcattgaa tatcgtgatt ctagcagttt tgacggcaac gaatattcta
     1021 ccagtcaatt ttgaagcact ggcaacaatc gttatcatga tggctacacc agctgcaaca
     1081 gtggcagcag cctatgctat cagttttgat agggaggcac ttttagcctc caatgcatcc
     1141 ttactgtcaa ctatttttgc tgtggtactg acacctgtat ggatcgttgt attacaaatg
     1201 attcatggca taggtttatt ttcataagaa atggaggaag aaagtatgag aatcgcatgt
     1261 tacggtgttc gtccgaacga gatagatttt tttgaaaaat tgaatattta ccattatgat
     1321 ctcagtcttt atgaagaact gttgacacat gacaatatcg tgtcagcaaa ggaccatgat
     1381 gctgtattgt tgaggggaaa ttgtatagca gatgagacca atcttgcaaa aatgcaggaa
     1441 tatgggattc gttatgtttt tacacggact gtgggagtca atcatatcga tctacaagcg
     1501 gcagctgatt ttggtatgac agtagcccgt gtaccatcgt attcgccaaa tgcgatagca
     1561 gagttatctt tgacttttgc catgatgctt ttgagaaata ctgcgtatac gacgatccga
     1621 acatctttca aagattttcg agtggatgag caaatgttta gtcgtgaaat cagaaattgc
     1681 acagtaggga tcataggaac aggcaggata gggttgacgg aagctgtttt gtttaaggga
     1741 ctaggagcca aagtgatcgg ctacgatatt catcagacag aagctgctaa aaaagtattg
     1801 acgttccact cgcttgaaga gttattagcc aaaagcgata ttgtcagtat tcatgtacct
     1861 catatcccag gtgaaaacga tcaaatgatc aatgaaggat ttttagctca aatgaaaaaa
     1921 ggtagcatct tgattaatac agcccgtgga gagcttcaag ataatgaagc tattttaaga
     1981 gctttgaaaa gcaatcattt agctggtttt gcaaccgatg tttttgcaaa tgaaacagag
     2041 gtttttttcc gatccttcaa gccatgggag acgattccag accctgctat ccagcaatta
     2101 gtagaaatgt accctagagt tcttgtaacc ccgcatgtag gttcaaatac agatgaggca
     2161 ttatcaaata tgatttcgac aagtttcgag aactttcgtg aaataataga aactggaaaa
     2221 acgaaaaatg aggtatctct tcctaaagcc cgtcaattaa gataagaaaa catggatatt
     2281 cgtcaataaa atgtttaaaa atagtccaag taaacagttg ttacttctgt atacttggac
     2341 tattttgtat gggataattc gatgactcaa cagtaatctg tgagcttttt ccgcccattc
     2401 tttgtcaatt cataacaggt tagcggccgg ccgatttcca aatatttgat tctttcgttc
     2461 aatatatctt gttctactaa aaaattcaaa tatttcttga cggatatacg tgacagtgag
     2521 cttttttgag ccagttcttt tgttgaaaaa atagtatctt cttttagaat aaatgcactt
     2581 atttttttta aagtcagttt tgacagacct ttaggcaaat cgatgaatga tggtatttcg
     2641 tgaatgggag tggtgtggtt gaatacttga tcgatcaatt tctgatcggc tttttcagtc
     2701 gtttggattg tctgagagaa agcaagatac ttttcgatcg ccagctgaaa acgttgcaaa
     2761 gtgaacggtt tgatcaaata atctaaggca ccgtagcgga tcacattctt tatggtttcg
     2821 atatcatctg cagcagtgat caaaatcact gggatatcat ttccttgctg tctaagccaa
     2881 gataaaaaat ggataccact ttcgccaggc atgtatacat caagcagcag cagatctgcg
     2941 tttttttgtc tgaaatattt ttttccttct tctacatttc tgaaactttc gattacgttc
     3001 atattaggga tgctttccac aaaagtacga ttcaattctg caaccattgg atcatcttcg
     3061 attatcagga catttgtcat cattttgatc ttcctttttt ggtaattcta gatagacgat
     3121 tgtaccgcca tttgtttgtt tggaaaattc taaaaatcca ccgtggcgtt tgacgattga
     3181 atggatgaga ttcaatccaa acccacgatt gattcccttc gtcgaaaaac ctagcgtaaa
     3241 tattttttct gagatttctt ctgatatccc gacaccgtca tcgcagacgg tcacgatgaa
     3301 tacttcagct tctgtgtcat agtttaaatg aatccggacc tgtccgtttc tttcatgttt
     3361 ttgtagcacg gcttcttttg cattatcaag taagttccct aacacttgca aaagtgaatg
     3421 gatggagtca tccatctcca ttttagggat aaaagaatcg ctttctaaca gcatttcaac
     3481 agattgttct ttggcttcgt ttattttgcc taataaaaaa ccggcaattg caggtacttt
     3541 gatcagactt gagacttggc caatctcttt tttataattt tgatttagct gctggataaa
     3601 atgggtgact tcttcatact tcttcaaatc aatcaaacca gaaatgacat gaagtttatt
     3661 catgaattca tgggtttgag ctctcatgga gtttatatat tgtttcgtcc ccccaagctc
     3721 ctccattaat ttcattactt ctgatcgatt tcgtaaagtt gcgactgctc ctaaaaaacg
     3781 gtcattgcta aaaagaggtg taacgctaga aatagtttct atcccattta aatacatgga
     3841 ttgagtccga acggtcgttt gatgctcaat cgtctcttta aacaaaacgt catatagatt
     3901 atcactgatt tttttcctac ttcgaaatcc aatagctgct ctgtttggta gaaaatgttt
     3961 tttgcaggtg tattgatcaa gaggatagtt ttatcagaag agatggctaa gattccttca
     4021 tctacttcat tttcgataat cgttttttca cttaactgtt ctgctatttc ttgtggttca
     4081 agtccaagca gtactttttt cattttttgg gcaagaaaaa cggcgcctat gatgcctacg
     4141 ctaagtccaa taatcaatga aaaaacaatc attttttgtc catctttgac ttgattgtca
     4201 atcgtgttgt ttgttaagcc aacacaaact gcaccaataa tctcttgatc ataataaata
     4261 gggacgaaat agcggaagcc gaaccctaac attccttctt tttcagagaa aaattcttgt
     4321 cctccaatca cttttttcac atcttcatga cttgagaaag gaagaccgat gtaacttggg
     4381 tctgcgtgag aatatcgaat gccttcaggg tccatgacaa cgataaaatc taaattcgat
     4441 gcaatcatga tttcatttgt tattccttga atcgcatgtg tcgggtcacc agtctgcagc
     4501 tttttttgga tgagtttatc attggcaacg attttagcaa tgctagagat tttatctgac
     4561 acactagatc ggttcatcga aagaataaaa ttcctgatca atatggcaga aacaatcaaa
     4621 gaaacgaatg tggagaaaca aacgacaagg atgatcgtgt tctggagctt taatggtttt
     4681 ttcttaaaaa aaggaaacat aggctacctc gaaagaattt attgtgaaaa ttttaacatg
     4741 aaaacaaaaa tttaacaaat tgtcaacgat aaacacaacc ttcctataaa aaacaccact
     4801 gagtcggtaa aagaagctat acagaatttt caaacattgg tatgatagac gtagaaatgg
     4861 aaggaggcgt gtatatgata gggggaatcg cacttgagac gatttattgg tatacattgc
     4921 tgatttgtgc aggattggca gtcctattga ttatttttgg agatgtattc gattttgatg
     4981 gcccgcttga tccgatgctt attatccctt ggttaacttt cacaagctta tttggttttc
     5041 taggtgagcg tttaacagat caatcatctt tatttttatt tattgctagt ggaggcatat
     5101 cgatagtgtt ggtatttttg cttaatttct atatattgat gccgatgaaa catgccgaat
     5161 caacgatgtc gtcttctgaa aaaactctgg aaggacaagt agctgttgtg atcacaccga
     5221 tccctgtacg aggtatggga gaaattcagt tgaaaagtgt taccggttcc attagtcgtc
     5281 cagcttgttt ttacagcccc caagaacaga cagctgagcg gggaacgaaa gtattgatca
     5341 ttgagatcaa ggaaagaatc tgttatgtca tgccttatga aagcatgata aaagcttaaa
     5401 ggagcgtgtg ttaaatggaa ataccagttg tttttatcgc gatcgcaatc gcagctttga
     5461 ttttactgat gttgctgatc gtctttgtag cgaagtacca gacagcaaaa ccggatgaag
     5521 cgttgatcat cagtggaagt tatttaggaa gcaaaaatgt gcacattgat gaaagcaata
     5581 acaaaatcaa aattgtgcgt ggaggtggcg cattcgtctt gccagttttt caacgttcga
     5641 atcggatcag tctattatcg agtaaattgg acgtctccac ccctgaagtg tatacggaac
     5701 aaggcgtacc ggtgatgtgt gatggtactt cgatcatcaa aatcggttca tctgtagaag
     5761 agattgctac agcagcagaa cagtttttag gcaagacaag agaagaactg gaaaatgaag
     5821 caagagaagt attagaagga cacttgcgct cgattcttgg ttctatgact gtagaagaaa
     5881 tctatcaaaa tcgcgataag ttcagtcaaa gcgtacaaga agtcgcttct gtagaccttg
     5941 caaaaatggg gttgatcatc gtttctttca ctatcaaaga ggtcagagac aaaaacggtt
     6001 atcttgactc tttagggaaa ccaagaatcg cccaagtcaa aagagatgca gatatagcag
     6061 aagcggaagc tctaaaagaa acgcgtatca aaaaagctca agcagaaaaa gaatcacaag
     6121 cagctgaatt acagcgacaa acagagatcg cagaatcatt aaaagaaaaa gaactgaaat
     6181 tagcaaccta caaacaagaa caagatgttg ctaaagcaaa agcagaccaa gcctacaatt
     6241 tagaaagtgc ccgagcacaa caacaagtaa tcgaacagga aatgcagatt aaaatcgtag
     6301 aacgtcaaaa acaaatcgaa ctggaagaaa aagaaatcac acgtcgtgaa aagcaatatg
     6361 attcggaagt gaagaaaaaa gcagatgccg atcggtacgc taaagaacaa gaagcacaag
     6421 ctcaaaaagt caaagaagtg actgaagccg aagcagaacg attccgtgtg gaagcactgg
     6481 cagaagcgga agccaataag acacgtttag ctggacaagc agaagccgaa gcagcactag
     6541 caaaaggaaa agcagaagcc gaagcaaaac aaaagatcgc caatgccttc aaggaatatg
     6601 gcgaagcagc tgtcttgagt atggttatcg atatgctacc gcaattgatg cgcgaagcag
     6661 cacagccgct aggaaatatc gaaaaaatct ctgttgtcga tacaggaagc agttcaggag
     6721 aaaccagtgg agcgaaccga gtgacaaatt atgccacaaa tttgctttct tctactcaag
     6781 aaacactaaa agcgacaaca ggacttgact tgaaggaaat cgtagagaat ttgtcgacac
     6841 gtgggactac tagccaagta aatatgtatg aagcgccaaa agaggcagaa caaaactcga
     6901 tgaaggaaga ataaagtagt acacttcacc gttcaatcaa aaatggagga agacttttta
     6961 aagttcttct ctccattttt ttattttatt gcaaaagaaa attagtcctc gctatttttc
     7021 ttttgttttt ggatcttagc ttctatctct tgtaaatttg ttcttagcaa tcgttctttc
     7081 ttttggagtt cgaccaaatc ttctgatagt tcttccttct tttctgtttc aggaggacga
     7141 agaaagaaat tgataccgat tgcaatgaat gtccctataa aagtatctag tacacgttgg
     7201 atagcataca aagcggattc gccttgaggg atgctcaacg caatcagcaa caacgtagct
     7261 attgcggaaa tgataccgga attattgtta ataccatctg acacgacgat cacaataata
     7321 actagaatag gaagcaagat caattctacc aaaaaatcat tgtgaaaata gcttttgaca
     7381 aaaaaataaa tgatagctaa tgtaccacct aatgtattgc cgatgatcct agactttcca
     7441 aaagaaacgg ttgtagtcaa gtcctgacgc aaagaaaaaa cagcagataa tgcagcaatc
     7501 atcgggattc ctcgttgagt caaatgaaaa aacaagatac ataaaaaaac agctaaggca
     7561 cttttgatcg tacgcatacc tagtcgaaaa cggccaaatt gcatagagat tctccttttt
     7621 ggtcttttta ctatcatacc taaacttttg tctgatagct agtttttcat tattcaagta
     7681 taattaaaat aaaaaagggg gaagtaaatg cgtataggaa tgcgaacagt caaaacagtg
     7741 atcagtgtct tcttttcgat ggtcacagcg ggtagcttat cgctgttgta ttggccagct
     7801 gcagggatca ttgcattatt aagtgtagga aataccaagc gctctacatt gcgtacgggc
     7861 atgaatcgaa tcgcagcctt tatattagct acggcaacag cactgttcag tttttttgct
     7921 gttgggtata ctatttttgg cttcagtctt tttttattcc tgttcatccc gcttgcctct
     7981 cgcttcaaat taaccgaagg gatagtagta aattcggttt tggtcactca ttatttagtg
     8041 gaggaaaaca tgtcttggca gctgatcggc aatgaagcgg gattaatggc gattggatta
     8101 gtatttgctt tgcttgcaaa tgtttacatg ccagatcgta cgaagcagct gaaggaaaac
     8161 caaatacaga tcgaaaaaga atttcgaaat attttgagac aaatggcaga atttctttta
     8221 tcagaaaata aagaagatgt gcagatcaaa tgcgaacatt tactgacatt cattcgcgaa
     8281 agccaagaag atgccagaga acatcaagaa aactactggc tcagacagcc gctatactac
     8341 gaaacttact tctctatgag aagagcacag gccaatgtga ttaaagacat gctggaaaat
     8401 ctagagagaa tccagcaacc agcttattat ggaaaacata tctatggttt attgatttat
     8461 actgcagaaa cattttcaga gtcaaatgat ggcagacaaa ttttaacacg tattgaagaa
     8521 gtttatgtat tgtatcggca aatgcctctg ccgactagtc gccctgaatt cgaggatcga
     8581 gcagaattgt tccagttttt gcagtctttt aaaagtttta ttgaaatcaa ggcagaattc
     8641 tcccaacaaa aaatccaaaa atagaggttg tgaattcagc taatattcag gtcaaaaagc
     8701 tgatttcaca acctcttctt taaacggtgt tctcctgtca actcctcggt cacaagtcac
     8761 aatattcaac aaacatgaga agctgttttt tgaaattgct ccttgtgact cggagctgaa
     8821 cggtaggctc acaacctctt tcttaaacgg tgttcaaaag ctttcctctg cggtaataag
     8881 tccagccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat tacttgatgc
     8941 agaacagctt tttcacaacc ttttaaaatt acatattttt ccatagaact tgcatttgat
     9001 ccaagatttc gatgacatct tttgtcaaga agagagagcg attgggcaag tcaccttcaa
     9061 tcatgtgtac catattcttt atttcgtaat tcattgcttc agatgtattc ccgctttcga
     9121 tgaattcctt tgtaccatct gtaaataaga tctccgcacg atcagcacgc gggtaatcag
     9181 caatcgtcac ataaccgttc tcaaaggcaa cgataccgac ttttggcatt tttgcctgaa
     9241 aagtcaagct gacagcagca agttcatttt ctttgttacg caagatagtg acggattgtt
     9301 cgtccacgcc tgtttcaaaa ggaaccattg tagaggcaac tacttcaggt tgagagctca
     9361 aaaagaaacg agcgaaagat acagcatacg taccgatatc caacagagct cctccagcta
     9421 attctggatt gaagaaccgg tttttagggt ctggttcttt gtaactgccg aaaggtgctt
     9481 ggatcatttt taaagccccc agttttcctg tatccattat tgagcgtaac tgctgataaa
     9541 gtggcatgtt gaagattgtc atcgcttctg ctaagatcaa attcttttct tctgctaagc
     9601 gcatagcgtc agccagttct tttttattca tcgtgatggc tttttcacat agaacgtgtt
     9661 tgcctgcttc caatgctgcc aagatatggt cgatatgctg tctatttggt acagcaatgt
     9721 acacgatgtc gatttcagca tcgtctaaca tttcttgata gcttccgtaa gcttttggaa
     9781 tattgtaacg gtgagcgaag ttttccgctt tttctgaagt tctggaagca actgctgtta
     9841 gttcgctcgt ctcttgattg aagctttcgg caaactcatg tgcgatggta ccaagaccaa
     9901 cgattcccca ttgatatttt ttcatctgaa aacgctcctt catagttgga ttgagtttct
     9961 tgtctgtcta ttattataac aaaaatcacg aagaataaag aggagaggac ttgaaacatt
    10021 aaaaaaaatg aaagcagcga tttaagaggt gctttttgat caaaacttaa gtagaatagt
    10081 taaaaggagg ggataaacgt gcatcaagta tatattgatc ttattatgag tgtattatta
    10141 gaacagtttg aaactgaaaa aaatttttta gatgaatact tgctgatcag tccagaacaa
    10201 tggcaaaaat ggaaagatgg cgagaaaaat ctgccatctg aagcgatgca gaaagtaaaa
    10261 aatcttttca ctgattatga atggatgcta acgcaaaaga ttttgcgtca aacgattatt
    10321 tttcccgaaa aacgaaacgt tgccgttgca gagtacaagc aaatcaaaac acgcatcgcg
    10381 caaaaatggc ttagcagcaa agcagcaaaa gtcgagctga tccctttgaa aaataatcag
    10441 caggctggta gataccttga cttgaaagta agtattcaat atgatgaatg gggctatgat
    10501 gatattttga attttcgtct gccagcagat gttcaaaaac agatcgaagg agaaaaaatc
    10561 gaacttctcg attgggtgaa tgaaaatctg gaagaaactt acgttcatga ggcgaatggg
    10621 gaacgtgaag aacaacgaaa ggatttttca agtgaataaa tttttaggat ttggagcagt
    10681 tgtgattatg atcgcagcaa tgggctatgt tatttttagc gatgatgatt cgcatgttca
    10741 agccggcaat caagcagtcg aacgaacaag caccaaaaca actgctagta aagaaaagaa
    10801 cagtcaaaca accagcagca aggtaaagga caaagaaaca aaagatcgta cgtccaaaca
    10861 attgccagat gttaaaacag acgattggaa gctagttttg gttggtccag atcacaaatt
    10921 agaaaaagaa attgatgagt ctactcaatt ggcatcatta agtaacggat acttgatcga
    10981 caaacgcatt gctccagaat atgaagcatt tgccaaggct gctgaagcag ctggatttcc
    11041 attagtgatg gtctcagctt accggtctgt atcatcccaa caacaagttt tcgaacaaaa
    11101 tgtccaagat gtgatgagtc gtcaaggtgt atcagaagag gaggcgacaa agattactaa
    11161 agaaacgatt acggagccag gatacagcga acaccacaca ggtctggcag tcgatgtcgt
    11221 cgatcaaaac tggtacaaca gttatccttc tactgtattg gatgcaagtt acggagatca
    11281 gcctggagct aaatggatcg cagataatgc tgcgcagtat ggatttatcg ttcgttatcc
    11341 aaaaggacac gaagatataa ctaagatcac atatgaacct tggcacttac gttatgtcgg
    11401 taaagaaaac gctgagtata tcaccaaaca ccaattgacg ctagaagaat atctgaatga
    11461 attaaatgaa aagtaggaat tgatcatggc gaaaaaaaag tggaaaaagc aaaagcgcaa
    11521 gaatatccgt tggccagcag tggttgccgg tgtagcagtg atactcttag cctttgtttt
    11581 ttccttgaag aatctgtctt ctccttttac tgataatcag caagaaaatg aagcgcaatc
    11641 ccatcagcaa tttattgaac ggcttgttcc gcatgcccaa gaactacaag atggttatgg
    11701 agtgcttcct agtatcattt taggacaagc tatattagaa tcaaattggg gaaaaagtac
    11761 cttggctagc aaatacaata atcttttcgg gatcaaggct tatggggatc agaagaaagt
    11821 aagcctggaa acaaaggaat ttgttaacga agaatggata actatccaag gagacttcaa
    11881 agtgtatgat tcatgggaac agtccatgga tgaccataca caactgttcg tccaaggagt
    11941 agattggaat cctgcgctgt atgaaaaagt gattacggcc accaactatc aggaagccgc
    12001 acaagcattg caagatgcag gttatgcgac agaccccggt tatgcgcaaa aaatcatcca
    12061 ggtcatcgag acgtatcaat tgaatcagta tgaccggaga tagcaaagga gaagtggctg
    12121 atggcagaac aatttacgcc agaaatcatg acggaattga gaaaagatat cgtaagagta
    12181 ccggaaatca ttttagaagc aagcgggatc aagatatttg gaaaattgat ccgttcgatc
    12241 atctttacta cggatattgc gatcatacgt aatacaaatg cgaatgcagt aattgctgtg
    12301 tatcctttta cacctcatcc agcgattact aaaagcatta ttgaggcagc tgacattcca
    12361 gttttctccg gtgtaggtgg tggtttgaca caaggtgctc gttcttccta catgagcatg
    12421 ttcgcagaag cgcaaggttc gttaggggtc gttttgaacg gtcctacgcc tttagagaca
    12481 gtaaaagaag tttgtcgagt agttgatatt ccagttatca gtacggtaac gtcgaaatat
    12541 acagaaatag atgaaaagtt agcagctggt atttcgatta tcaatatcag tgcaggtaaa
    12601 gaaactgcag aagcagtacg ccattttcgt aaaaaatatc ctgaacttcc tatcattgcg
    12661 acaggtggtc caacggaaga aagtattgct gagaccattc aagcaggagc aaatgccatc
    12721 acatatacgc caccaagtag cggagagctt tttagtcgta aaatggaaaa atatcgggaa
    12781 actgagaaaa agaatcatga ataacaggtg agaatcaaaa gacgaggaag agcagatagt
    12841 ggctcttcct cgtcttttgt actccagtac tatttgttca gaattcaaaa aaaagagaaa
    12901 tttttttgtt tttttacctg taatgtacat aagaagagtt aaaacctttt gttattatta
    12961 gcattctaac aaaaaaatgt cttgatttat tgaagcgctt tctatagaat gaaaaacgaa
    13021 taaaaactaa aaaaggcacc cgacaattta gtagcagcta aattgtcggg gcttgaaaag
    13081 tcagcgggaa ctgaccaatc aagttgccat agtcaatgct tgtgcatcga cgtgtatatt
    13141 gtacctaatt tcatacagaa ttactagtta tttttctgtt ttttagggaa gagcgcacac
    13201 gaagaagcat gcttatttag ctatgtcaag gatattgggc agttgtctga tatccttttt
    13261 tctttgcgta attatcctcc catcattgaa gcaagaagtg tttttagcga tgaaagaaga
    13321 atcagcacta tctaattttt cttgaaagta ttgagttgtt catcctaggc agaacgataa
    13381 ggcaagtctt ggtttttatt ccccttgaaa aagatcgttt aataaatatg ttctgtataa
    13441 aaatacagta tattgaaaaa taacaatgga agtagaggtg cagagaatga agaaaagaat
    13501 gagaatcatc ttagctttaa gtgttatgtt attcttcttg acggcttgtg ggcaagaaga
    13561 tgacaaaaaa atcacgctga acatggcttg gtggggttcg caagtccgac acgatgcaac
    13621 agtaaaagta atcgagcttt atgaagaaaa aaatccccat gtgacgatcg attatgaatt
    13681 ttatgattat gaaggatatt acacaaaatt aggtacacta gcagcatcag atgatatctg
    13741 ggacattttc caactgaaca atcaatttcc tcaatacatc aatcagattg aaccattaga
    13801 tgaatatgtg gagcaaggga taattgatat ttctaatgca gatgaatcct atttagcaac
    13861 gacgacttac gacgggcaat tagttggact gtctaacggg gtgaattcgt ttgcgattgc
    13921 ttacaataaa aatatatttg aacaattaaa tatccctgaa ccagcttcaa attggacatg
    13981 ggatgaattt gaacaaatca gctatcaaat cactgaagaa ttaggaatct atgctatttc
    14041 aagattcgaa gattttatag ctggctgtat tattcaaata ccacaagttg agaaaggatt
    14101 gaatttttat aatcgggaag atctatctaa cagcttggga tttgaaaatc cagactatct
    14161 aacagatttt ttccagctgc gtaaaaatct ggtagacaaa ggggcccatc cagaaccagg
    14221 tggtggagct gcaagtacga cggatctgtc ttttcaggcg gttagggata gagaagcggc
    14281 aatggtgttt ctatcaagta accagttgac agaaatattg tcaggggctc ctgaagatat
    14341 ggagattcag ttgattaatc cacctcgcag aaaagcagat ggagaatctg gtatcccttt
    14401 acgttcttcg caaatgctga gtatggcaaa aagctcagcc cataaagaag aagctgctaa
    14461 gtttattgat ttctttcaaa acagtgaaga agccaatgaa attttaaaag gagaacgtgg
    14521 tgtaccaatc atgtcgaata ttcgagaaca gctcgctcgt gcagatgatg caactttgca
    14581 agcgacattt gattatttag aaatgatttc cgatatggac aacggcgaag tgaatgtctt
    14641 tgatagtgct ttgaatccgg aaattcaaga ccaatacaat cttttagttg aaaaagtcat
    14701 ttatgaagaa gtaacagcag aagaagcagc agagagtctt tatgagtttg cgtcaaacat
    14761 tctaggatag cagcaggagg aaggcatgaa aaaagaaaaa ctaaaacggt tcttggatca
    14821 agacaatgtg gtcggttacg tatttgcttc tccattcatc ctaggatttc tattgataac
    14881 agtgataccg atgatcttgt cactttatta ttcgttcacc gattatcgtt tgggaaatcc
    14941 agtctcatgg atcggcttgg ataattatat aaagatgctg agtgatgccc gttttttgaa
    15001 ctccatccga gtcacttttc tctatgtatt tgcatctgta cctgtgaaac tgatctttgg
    15061 tctattgatt gcttatcttt taacgaggaa tatcaaagga acgactttct ttcgttcttt
    15121 gtattatgtg cctagtttga tcggtggcag tatttctatc gctctagttt ggcgggagtt
    15181 gttttctaaa aacgggttag tgaatatttt cctggaacga ttaggcgcac ctgcgctttc
    15241 ctggtttagc gatcaaaaac tggtcatgat ccctcttgtt ttgatgtctg cttggcaatt
    15301 cggttcggca atgatcatct ttgctgcagg tatcaaagag atcccaggct cgtattatga
    15361 agcggcagag atcgatggag cgaacaaatg gcagacgttt tacaagatca cgttacctct
    15421 tctttcgccg atcattttgt ataacttggt tatgcagaca atcgcggcgt ttatgacttt
    15481 tacgcaggca tttatcatta cccaaggtgg tccgaatgat gccacgaact tttatgctct
    15541 ttatgtgtat aaccaagctt tttcttttaa ttctatgggg tatgctagtg ctatttcgtg
    15601 gatcatgctg ttgattatgg gagctgtcac ctttctgatt ttcaaatcat caaaaaaatg
    15661 ggtcgttgtg tgaatgagag gaggaagaaa tgaataatac agtaacgaaa tggtttcaat
    15721 acggttttat tttgctatta ggtctagtca tgatttatcc ggtcttatgg atgatcgcag
    15781 gttcttttaa aacggatcaa gagattatga gtggttcgct gaatttgatt ccagagactt
    15841 ttcaatggga aaattacgca aaaggatggg cggggtttgc tggaatttca ttttttactt
    15901 tctttaggaa ttcgtttgtc atctctgcag tttcgacgat agggacagtt ctgagctcga
    15961 cttgtattgc ttacgcatta tcgagaatcg atttcaaagg aaaaagattc tggttcgtcg
    16021 tcatgttagt aacgatgatg attcctgcac aagtgatttt gattccgcag tttattattt
    16081 acaatcggct gaatttggtt gggacgtatg tgccgctgat tttaccacat ttttttggac
    16141 aagcattttt catttaccag atcatgcaat tcatggtcag catccccaaa gagttagatg
    16201 aatcagcgat tattgacgga tgcagcaagt atagtgtctt taccaaaatt atttttcctt
    16261 tgctgaaacc ttcgatcatc acgacgatca tcatccagtt ttattggaaa tgggacgact
    16321 tcatgggacc attgatttat ttaaacaagc cgagatctta cacggtatcg attgccatca
    16381 aattatttgc agacgctgga tctagtacga cttacgcgag tatgtttgcg atgtctacgt
    16441 tgtcgctgct accggttttt ctgattttct tattcttcaa taaatatctt gtccagggga
    16501 tcagtacaag cggtctgaag ggctgaatat gaaaaagcca atagaagaga tgtttcttta
    16561 caagctcaac tactatgtct gtcggatttt tttaaccagt cttatcagta atgctctttt
    16621 cgctttagtt ctaggatgtt tgttcacttt aggattagtg ctgtctgctc gtgttgtcta
    16681 tctgatttat tttttgatga tgtatccttc ttattatcta tctgtccatt acttggcaga
    16741 aaaaaaggta tgttggagga aaggaaaaat caaacggatg tgtttcatca ttacgttgtt
    16801 tcagctgttt gtcattattt ttgcagttga ttggtattta ttagtgggaa agattggagc
    16861 ttggtatctg attccttttc tattgtgtct gttgcttttt gtatcccata gtttttttag
    16921 tacgctaatt gatatctgca aagaagataa agcagatagt cttgtttatt tgatcaaaag
    16981 gaatatctgg ctgttgtcaa aaaacgtcaa ggggtttctg tggtatttat gccttttgta
    17041 tggactgttc tggtgtatac agcatgattt tttactcact gcattactgt atccagggct
    17101 gccatttgtc acagtatttt gcttaaaaga aaaggagaat gactttaaat gaagaaaaaa
    17161 tatgtacaag tcggacttgg tgggagagcg cgtttttttt atgaggcaat tgcctctacg
    17221 tatcatcaaa cttgtgaact agtcggtttt tgtgatgtat ctcaaacaag gatggattat
    17281 gcaaatcgga tacttgtgaa caagtatgga cagaaaaaag taaagacatg tatgccatca
    17341 caatttgagc aactactgga tgacgtacgg ccggctgaag tcattattac gtcagtagat
    17401 cgaacgcatc atgattatat cattcgtgca atgaaaaaag gatatgatgt tatttgcgaa
    17461 aaacctctga ctatcgatga ggaaaaagct caagaaataa taacggtcca aaaacagacg
    17521 ggaagaagcc tgcgagtcac ttttaattat cgttatgcac cgtatcacac gaagataaag
    17581 gaactgatag aaagtgatgt gattggtgat gtgttttcta tccacttcga atggctgtta
    17641 aatacgcaac acggggcaga ttatttcaga agatggcatc gaaataagca caatagcggc
    17701 gggcttcttg ttcataaatc tacccatcat tttgatctag tgaatttttg gttgaacagc
    17761 cgtccccaaa aggtatttgc attcggtgga ttaaactttt atgggatgca taatgcggag
    17821 aaacgcggag tagaaatatt ttacagtcga tgctatggaa gcgaactagc taaagctgat
    17881 ccatttgcta tagacctgtc agccaatgag gaattgcgag aaatgtattt agaagcagaa
    17941 aaagacagtg gatatattcg tgaccgcagt gtattttccg atgatatctc tattgaagat
    18001 acactaggcg taacggtcaa atatgaaact ggtgcgattt tgacgtattc gctaaacgcg
    18061 tatatgccgt gggaaggatt caatgtttct ttcaatggca gcaaaggacg gatcgaaatg
    18121 aaagtgatcg aaaagtctta catcaatgca ggtggagata aaaaggatga aggagcagcc
    18181 gttcttcagt ccatccatgt ctatccgatg ttcggtgagc catatgaggt aatcgtcgaa
    18241 caagaagcgg gcggacatgg cggaggagat ccgcgtttat tagatgatct atttggtgaa
    18301 gaaaaagaag aagatccgtg gaatcgggca gcaactcacg tagatggtat tttgtcgatt
    18361 ttgacaggaa tcgcagcaaa tcattctatt gcttcaggaa aagcagtagt gattgacgag
    18421 cttgtcagct taaaagaata agaatagatt tacggaaatt acttcccgta gtttataaaa
    18481 tcttgcctta ttgccgatag gctgtctttt gaacactatt tattcggaaa aaggggctat
    18541 gacatgcttt ttgtcatgcc ttctttttat gtgggctgct tttttagata ggagaaaata
    18601 aaaataacta tttaaacccg aacaaaaagg aataatgcat taaaaatcat tagattttac
    18661 aaaaaaataa gtaaaccacg ttgtcagttt cagaaagtag tgttagactg ttttcaatat
    18721 ttgaaacaac attttttatt caaatatggc aaactgcctt cacgtgcaaa acagttgcaa
    18781 gaaaatgaat ttacactatt attagtttta catacctact tatatatcgt cataatatgg
    18841 atgacagttt ctagccagta ccgtaaatgc tggactataa gtaaaagatt ggctatttca
    18901 cccttctttt cttatgataa agtggagggt gtttttcttt aacagaaaca tagtaggttt
    18961 ttgcacaaaa gcggttattt cggtattaat aaatgataaa ggagcaaata aagtgaaaga
    19021 attagttgaa cgtattcaaa aagacggacg tatattaggc gagggcgtat taaaagtcga
    19081 cagcttcgtc actcaccaag tagaccctgt attgatggaa caaatgggaa aacggtttgc
    19141 agaagtattt aaagaacaag gaatcacgaa agttgtgacc attgaagctt ctgggatcgc
    19201 accagcttta tttgctgcaa gagaattaga tgttccaatg atcttcgcta gaaaagcaaa
    19261 aagtttgacg atggatgaag aattattgac agcttctgtt tattctttta cgaaacaagt
    19321 gacaagtacg atttctattt ctcgtaaatt tttatcttca gaagacaaag tattgattat
    19381 cgacgatttc ttggcaaacg gacaagcggc aaaaggattg atcgaattat gccagcaagc
    19441 tggagcgcaa gtagaaggaa tcgggatcgt catcgaaaag tctttccaag atggacgtca
    19501 gttacttgaa gaaatgggat tgagagtcgt ttctcttgcg cgtattgctt ccttgacgaa
    19561 tggacaagtt gagtttcttg aggaggacgc ataatcgtgg aaaaagaaac acaaaatgga
    19621 aaagctgcgg ttttagggct gcagcatctg ctagcgatgt atgcaggagc agtagcggtg
    19681 cctcttttga tcggtacagg actaggcttt aatcaagaac agatgactta tttgatttca
    19741 attgatatct ttatgtgtgg attagcgaca ttattgcaat tgacagttaa ccgatttttc
    19801 ggaattggct tgcctgtcgt tttaggatgt gcgatccaag cagtagctcc actgatcttg
    19861 atcggaacca atgaaggagt aggagctatc tacggatcta ttatcgcttc tgggatcttt
    19921 gttgtgttag tttctggtgt cttttctaaa attaaaaaac tattccctcc tatagtaaca
    19981 ggaacggtta tcaccgttat tggtttgact ttgattcctg tagcaatcga gaaaatgggt
    20041 ggaggtaatg caacagcagc tgattttggt gacaaaacaa atctgctact tgcatttgtg
    20101 acgattctcc taattgtagg cgtgcaaatg ctggcaaaag ggttcattcg ttcaatcgcg
    20161 gtattgattg gtttagtcgg aggaagcatc ttagctgctt tcatgggaat gattgatctg
    20221 agcgcgattg gagatgcgcc gttgttccat gttccacaac ccttttattt tggtaaacca
    20281 actttcgacg tatggtcgat tttactaatg atcatcattt ccatggtcag catggtagaa
    20341 tcaacaggtg tatattttgc acttggtgac attactggga aaaatgttgg agaagaagaa
    20401 ttgaaaaagg gatatcgtgc agaaggactt gccgttatct taggcggtat tttcaataca
    20461 ttcccttata ctggcttttc tcaaaatgtc ggattggttc aactttcggg aatcaaaaca
    20521 agaaaaccca tctatttctc tgcattcttc ttgattgttt taggattatt ccctaaaatc
    20581 ggtgcgttag cacaaatcat ccctgagccg gtacttggtg gaggaatgtt agtcatgttc
    20641 gggatggtgg cagtccaagg aatccgtatg ctgttggaag ttgatttcag caatgataaa
    20701 aatctattga ttgttgctgt ttctgttgga tttgggctgg gtttcaatgt tacgccgaca
    20761 ttattcagtc aaatgccgca aacattgcaa atgttcactg gaaatggcat cgtaatgagt
    20821 agcattacgg ctatcatatt gaatttgatc tttaatggat tgaaaaaaga tgaagaaata
    20881 ttggaagaag ccttcaagaa gtaatagagc aaaagaaagg ttgtgaaatc agcgttttga
    20941 cctgattgtt agagaaacaa acggaaaaat agttcctcgt attttgccgt ttgtttgagc
    21001 taataccgag ggtcagctga ttgaacaccg ttgaaggaag aggtcgtgag cctgccgttc
    21061 atctccgagt cacaaggaac aatttcaaaa aaaagcttct catgtttgtt gaatattgtt
    21121 ccttgtgacc gaggagttgg caggagaaca ccgtttatcc ataaaaagga atgtgaccta
    21181 acttttgtca cattcctttt ttttatcttt aataaacacg aacaataaaa tgtttttctt
    21241 tgttaacatt cgaaatttct ttgacatcaa aaaaagtgat tgttaaaata tgaatgtaga
    21301 aaaactggga ggaaaaacaa tgacagcaaa aatctctgtg attatgggga gtacttcaga
    21361 ttgggaaaca atgaaagaag catgtcaaat attggatgaa ttcggtgtgt cttatgaaaa
    21421 aaaggtcgtt tctgctcatc gaaccccaga tttgatgttt gaatatgcac aaaacgctcg
    21481 aaaaaaagga atcaaaatca ttattgcagg agcaggggga gccgcgcatc tgccgggtat
    21541 ggtcgcatca aaaacaactt tgccggttat cggtgtaccg gtccaatcac gaacattaaa
    21601 tggtttggat tcgcttcttt cgattgtcca aatgcctgga ggagtacctg tagctactac
    21661 agcaatcgga aaagcgggag caattaatgc tggactactt gcgatacaga tgctttccat
    21721 gtatgattta gaattggagg ctaaattggc tgaaagacgt tcaatgttgg ctaaaactgt
    21781 tatagaaagt agtgatcaac ttggttaaac ctttgttgcc tggttcaacg atcgggatcg
    21841 tcggtggcgg tcaattaggt cgtatgatgg cgattagtgc aaaagaaatg ggctttaaag
    21901 taggtgtgct ggatcctgtg agcgattgtc cagccgcaca agttgcagat tggcatattg
    21961 aaagtgtcta tgatgacacc tttgcgctga aagagcttgc cagaagaaca gatgtcatta
    22021 cctatgaatt cgaaaacgtc agtgtagagg cgttaaatgc gattttaccc atgtcattta
    22081 ttcctcaagg gacagacttg cttgcgatta cgcaagaccg cctgttagaa aaatcttttt
    22141 tggaaacgaa taacatcgtg attgctcctt atgcaacgat cgtcagtccg acggatatcc
    22201 aagatgcgat tgacgggatc ggctatcctt gtgttttgaa aaccactcga ggcggctatg
    22261 atggcaaggg gcagtatgtt ttgaaaagtc gggcggatct agctcctgcc atggaccttt
    22321 taagagaagg aacctgtgtt ttagaagcat ggatcccgtt tgaaaaagag atttcgatca
    22381 tggtggcagg aaatggtcaa ggagatttca cgacttttcc ggtcgtggaa aacatccacc
    22441 acaacaatat tcttcatgaa acgattgctc cagccgcgat tgatcaggat gtgatcgagg
    22501 aggctgagcg tattgcccgt gtgattgcag aagcagtgag cctttcaggt gttttagggg
    22561 tagaaatgtt tttaacaaaa acaggcgggc tatatgtgaa tgaattagct cctcgtcctc
    22621 acaattctgg acattattct attgaagctt gttctatgag tcagttcgat gcccatattc
    22681 gaggtatttg tggttggcca ttaggagaaa aagtacgttt gataagcaat gcagtaatgg
    22741 tcaatgtttt gggagaacaa ctgctggaaa gctatcgctt gattgagaat aagccagact
    22801 ggcaattcca tttctatgga aaaaaacaag caaaaaaagg tcgcaagatg ggacatatca
    22861 ctatcttgac agaagacatc cagcaaacgc tggaagaaat caaacaaacg aatatttggg
    22921 attagaggag aaaaaacatg ttagaacgtt atacacgccc tgaaatgggg aatatctgga
    22981 cggaagagaa caaataccgt gcgtggctcg aagtcgagat tttagcagat gaagcttggg
    23041 cagaacttgg tgaaatcccg caagaagatg tgaaaaaaat tcgtgagcat gcatcatttg
    23101 atatcgatcg gatcttggaa atcgaaaaat taacacgcca tgatgtcgtt gcgtttacac
    23161 gagcggtttc tgaaacattg ggagaagaaa gaaaatgggt ccattatggt ctaacaagta
    23221 cggatgtcgt agatactgct tatggctatc tcatcaagca agcaaatgat attttacggg
    23281 aagacttgaa acgttttacg gaaatcattg gcgaaaaagc aaaagaacac aaatatacag
    23341 tgatgatggg tcggacacac ggtgtccatg ctgaaccaac tacttttgga ttgaaacttg
    23401 ccacatggta ttcagaaatg aaacggaaca tcgaacgatt tgaacatgcg gcaaaaggag
    23461 tagaagcagg aaaaatctca ggagcagtgg gaacgttcgc aaatatcccg ccatttattg
    23521 aagagtatgt atgtaaacaa ttggggatcc gtccacaaga aatttctact caagttctcc
    23581 ctcgggatct acatgctgaa tatttctcag cgatggcgct tattgctaca agtattgaac
    23641 gttttgcaac agagatacgc ggattgcaaa aatccgaaac acgtgaagta gaagaatttt
    23701 ttgcgaaagg tcaaaaaggt tcttctgcta tgccgcacaa aaggaatccg atcggttcag
    23761 aaaatatggc tggtctagcc agagtggtgc gcggacacat ggtcactgcc tatgaaaatg
    23821 tcacattatg gcatgaaaga gatatttctc attcttcagc agaacgaatc atcttgcctg
    23881 ataccacgat tttattgaat tacatgttaa atcgttttgg caatatcgtt aaaaatctaa
    23941 cggtctttcc tgaaaacatg aagcggaata tgtctgcaac atttggtttg atttatagcc
    24001 agcgcgttat gctgaaattg atcgataagg gaatgacaag agaagaagct tatgatcttg
    24061 ttcagccaaa aactgcgtac gcttgggaca accaagtgca gttccgcccg ctgttagaag
    24121 aagatccaac catcacatcg gtattatcta aagaagaaat agacgatgcc tttgattatc
    24181 atcatcattt gaaaaacgtt gacgtgatat tcaaacgagt aggtttggaa taaagaagag
    24241 tgagttgcaa aattcaatta aaatagaata gcaaaaataa ccaaaaaaga agcagatccg
    24301 ttagcggttc tgcttctttt agtttattat attttcttat caataatagg aacctgattt
    24361 taaaagcggc tacctcttta ccgtgcctct ttacatacaa aaaatagagg aattaagcgt
    24421 aaatggcttg gctattataa ctaaaatgct ggttatggag atgttgcagc aagttttcga
    24481 gaaaagcgta ttccatctct tgtccattga ataagatctg gatacgataa tgatttttga
    24541 aacgcttctg ttcatgaatc tgactgattg aaagttcgcc tttgtgttct gtctgataaa
    24601 gaaaagtcct tttacggcat tcagcacagc gcttggttgc tcggcggatt tttcggaatg
    24661 tataaaaact agtatcttta ttgcataaat aaacgtcttt gatcgacagc aaatcattat
    24721 atagacagga acgttcttca gctgttaatt ctgataaaaa aagctgacct tgttttattg
    24781 catcttccat cggcaagtgc ctcctcgaac ccattaacca aatttttagt taattctaat
    24841 ataccatcat taagtataaa tgtaaacgct tgttgatggt ataagatttt cgtttctgat
    24901 aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac atatttttgt tgatttataa
    24961 aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa aaacgatgta tttgctttta
    25021 atgtaaataa aaaggagaga cgtacatgga gaagaaagaa cttttgtatg aaggaaaagc
    25081 caaaaaaata tatcttactt ctgatgagaa cttgatttgg atagaatatt tagatcaagc
    25141 aactgcgttg aatggcgcga ggaaagacca gataagtgga aaaggagaat tgaataatca
    25201 aatcacaagt gcaattttcc gttatctgac tcaaagagga ataaaaaatc attttattga
    25261 acaattgtct aaaaccgaac aattagcaaa aaaagtacaa attatccctc tggaagtggt
    25321 tatccgaaat attgcagcag gaagtttctc aaaacgtcta ggtgttcccg aaggtaaaga
    25381 attcatcaaa ccaatcattg aattctacta taaggatgac cagttggatg atccatttat
    25441 caatgaagag catatctatt tcttacaact tgcaaagccg gaagaaatca gtgagctgaa
    25501 agcccaagcg ttggctatta atgaaatttt gaccgaatta tttgctaagg tcggtttggt
    25561 tttagtagat ttcaagctag aatttggccg gtcgaatgga caaattttgc ttgcggatga
    25621 agtaacaccg gatacttgcc gattatggga tgaacgtacg aatgaacata tggacaaaga
    25681 cgtttaccgc agagatctag gtgatttgat cccagtctat caagaagtat ataaccgtct
    25741 atcggaacta actgaagaaa aggagcgagt atgatgtatt tcgtaaaagt atatgtaacc
    25801 tataaagatt cagtgttaga tcctcaaggg gaggcagtaa aaaaagcagt ccatcgtatg
    25861 ggatatgaaa caatcgaaga tatccgaata ggaaaatact ttgagataca acttgctgat
    25921 gcagaagaac caatcgatac agtgattgaa acgatttgtg acaagctgct tgcaaatgta
    25981 aatatggaaa cataccgata tgaaatcaaa aaaatggagg aagtataaca tgaaatttgc
    26041 ggtcatcgtt tttccaggtt caaattgtga cgcagatatg ttatgggcag ttcgcgagat
    26101 catgggcgct gatgccgaat ttgtacggca tgatgagtcc tctttagaag gatttgatgg
    26161 ggttttactg ccgggaggat tctcctatgg tgactatttg agatgcggtg cgattgctcg
    26221 gttttctaca atcatggaag aagtgattcg ttttgctgaa gaagggaaac cagtattcgg
    26281 tacatgcaat ggattccaga tattgacaga agcaggactt ttgccaggtg tactgagacg
    26341 aaatgagtct ttgcatttta tttgcaaaac tgtaccattg aaagtcaacc ccaagacggc
    26401 ctttacttca gagtatgaag ccgacgaaat aatctatctt ccagttgctc atggggaagg
    26461 aaattatttc tgtgacgaag aaacacttca agaactaaaa aaaaataatc agattgcctt
    26521 tacttataat gacaacatca acggcagcgt ggaaaacatt gcagggatta cgaacaaagc
    26581 agggaatgtg ttaggaatga tgcctcatcc agaacgtgca gtagaagact tgctaggatc
    26641 agaagatggg aaacggttct ttgcttccat tttaaaaaac ttcggaaagg tgaccgtata
    26701 gatgaaaaca ttgaaagaac cgacagctga agagatcaag aaaaaaagaa tctatgccga
    26761 atggggattg actgatgaag aatatcgaat gatcgaagaa gatatcttag gaagaatgcc
    26821 taattatacg gaaactggac tgttttctgt tatgtggagc gaacattgtt cctataaaaa
    26881 ttctaaaccg gttctacgca aatttcctac tagtggacct catgtgttgc aaggccctgg
    26941 agaaggcgca ggcatcgtcg acatcggtga tggactagca gttgtcttca aagcagaaag
    27001 tcacaatcat ccttcagccg tggagcctta tgaaggagct gcgacaggag ttggcggaat
    27061 catcagagat attttcagca tgggggctcg tccaattgcg ttgctagatt cattgaggtt
    27121 cggcgaatta gataatccaa gaacgaaata tttactagaa gaagtagttg caggtatcgg
    27181 cggatacggc aattgtatcg gcataccgac tgtaggcggc gaaattgcat ttgatccttg
    27241 ttatgaagga aacccattag tcaatgcaat gtgcgtaggt ttgattgaac acaaacatat
    27301 ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg tatgtaggtg caaaaacagg
    27361 tcgcgacggt atccacggag caacttttgc ctcagaagaa tttaatcaag aagaagaaca
    27421 gcaacgttct gctgtacaag taggcgatcc ttttatggaa aagctgctgc ttgaagcgtg
    27481 tttggaatta atcttgcatc attcggattc tctaataggt atacaggata tgggagcagc
    27541 aggacttgtt tcatctagtg cggaaatggc ttcaaaagct ggctcaggac ttatattgac
    27601 attagatgaa gtcccacaaa gagaaactgg gatgacacct tatgaaatga tgttatcgga
    27661 atcacaagaa cggatgttga tttgtgttaa atcaggagag gaagaaaaaa tccaagaact
    27721 atttcagaag tatgatctag atgcagtcac tatcggtaaa gtaacagacg acgggcaata
    27781 tcggctatat catcaaggag aagaagtagc aaatctgcca gtcgatgcat tagctgaaga
    27841 tgcaccagtt tatcataaag aaatgaaaga accagctcga atcgtagaat ttcagcagtt
    27901 agctccttat cagccagtta tcgaagaacc tggacaagta ttgcttgatc tgctgcagca
    27961 accgacgatt gcttcaaaac gttcaatcta cgaaacttat gattcacaag tacaaaccaa
    28021 tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg gttagaggga cgaataaagc
    28081 gttagctatg accacagact gcaacgcgcg ctatctgtat ttggatccaa aaatcggagg
    28141 acaaatagca gtggcagaag ctgctagaaa tattattgct agcggtggta agcccttggc
    28201 gatcaccgac tgcctgaact atggttctcc tgataaacca gaagtttttt gggaattatc
    28261 gacttcagct gacggaattg ctgctgcgtg tgaaacgtta ggaactcctg ttatttcagg
    28321 aaatgtctct ttatataatg aaacggatgg tcaagcaatc tatccaacac caatgattgg
    28381 tatggtcgga ttgattgagg atcataaaca tatcactact caggaattca aaaaatcagg
    28441 ggatctaatc tatatattag gtaagacgtt tgcagatttt gatggcagtg aattacaaaa
    28501 gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt gatctatcca ttgaaaagag
    28561 aaaccaagag ttagtattga cagccatcca aaacggattg attgaaagtg ctcatgactg
    28621 ttcagaaggt ggcttggcaa ttgcactggc agaatcagct ttcaaacatc agctagggat
    28681 atctgtacag tttgaattgt cctctgctca attatttgca gaaactcaat caagatttgt
    28741 gttgacagtc gcaccggaaa ataagacacg attcgaagaa atgatgggag atgctgctgt
    28801 tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt tcagcaactg acggtcagat
    28861 caaaatagaa actgcagtag caagaaagtg ctgggaggat gcaatcgtat gtcttatgaa
    28921 gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt ggggtcatcc agacgccgct
    28981 agtgtggcat acttcgggct ccatagtctt cagcatcgag gacaagaagg tgcaggtatc
    29041 gtgtccaatg atcgaggaaa gcttaagggg catcgagatt tggggctgct ttctgaggta
    29101 ttcaaagatc aaagaaaatt gcagcagtta acaggagaag ctgcaatcgg acatgtacgt
    29161 tatgcaacag caggcaatgg aagtgtggac aatattcagc cttttctatt caaatttcat
    29221 gatcagtcga tcggcttagc gcataatggt aacttgatca atgctcgttc ccttagaaaa
    29281 gagttagagg aaaatggggc gatcttccat tctaactccg atacggagat attgatgcat
    29341 ttgatccgac gaagtgaaga aacagatttt ttaaataaat taaaaagtgc tttgaatgaa
    29401 gtcaaaggtg gctttgccta tttattaatg acagaaacgg caatgattgc cgctttggac
    29461 ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa acggagcata cgtgattgcc
    29521 tcggaaactt gtgcattaga agttattggg gcacgtttta taagagatgt ccagcctggt
    29581 gagatagtga tcatcaatga cgaaggaatc cagattgatt gctttacgaa ggacacgcag
    29641 ctttctattt gttcgatgga atatatctat tttgccagac cagattcaaa catcgcaggg
    29701 atcaatgtgc atactgcacg gaaaaatatg ggacggaatt tagcgaaaga atcgccagta
    29761 aaagcagata tggtcgttgg cgtacctaat tcttctttgt cagccgcaag cggttatgcg
    29821 gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa atcaatacat tgcccgaaca
    29881 tttatccagc caacgcctga gctaagagag caaggtgttc gaatgaaatt atctgctgta
    29941 cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg attcaattgt tcggggtacg
    30001 acaagcagac ggatcgtcca tcttttgaaa gaagcagggg caaaagaagt ccatgtgagg
    30061 attgcttctc ctcctttgaa atatccatgt ttttacggga ttgatattca aacgcgtaaa
    30121 gaactcattg cggcaaatca cacgattgat gaaatcaaag aatgtatcgg tgcagattct
    30181 ttaggttttt taagtgaaga gggtctgatc gaatcgatcg gtctggaaaa agatgctccg
    30241 tattcaggat tgtgtatggc ttatttcaac ggagattatc cgacgccgtt atatgactat
    30301 gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt tcttttaaaa gcagaccaag
    30361 aagggagtat atgaattcaa tggcaaatgc atacgcaaaa gctggcgtag atgtcgaagc
    30421 tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa aaaacggaac gtttaggtat
    30481 gatgggcgct ataggaggat tcggcggttg ttttgattta tcggtctttc aattaaaaga
    30541 gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa ttagcagtgg caatcgaagc
    30601 agacaaacac gatacaatcg ggatcgactg cgtagcgatg tgtgtcaatg atatcttagc
    30661 acaaggcgca gagccgttat atttcttaga ctacttagca acggggaaaa atgatccgtt
    30721 acgtttggaa aatgtagtaa aaggtgtagc agatggatgt gttcaaggaa atatggcgct
    30781 gattggcgga gaaacagctg aaatgcctgg tatgtactca ggtaatgatt atgatctagc
    30841 cggatttgct gtagggatag ctgaaaaatc tcaattattg acaggagaaa cgatcaaccc
    30901 aggagatgtg ttgcttggaa tagcatctag cgggattcat tcaaatgggt actctcttgt
    30961 tcgcaaaatt ttctttgagc agcagcagtt ttctttatca tcaaaactgc cagaattgaa
    31021 aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc tatgtttctt ccttgcttcc
    31081 gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc actggtggag ggtttgtaga
    31141 aaatatcccg cgaatgttac cagaatctat ggctgcacaa atcaaacttg gctcatggcc
    31201 gattcttcca atattcggct gtttacaaaa atatggtgaa attcctgaga tggagatgta
    31261 tgaaatcttc aatatgggca tcggtatggt cctggcagtc gaagaatcga aagtaaaaga
    31321 aatagtacac gaaattgagc aagctggcga aaaagtttat gaaatcggga aagtgatcgc
    31381 caaagaaaaa catcgtgtgg tgtttatagg agaagaacga tgagaatcgc tgtttttgct
    31441 tctggaaacg gaagcaactt tcaagcgcta gccgattatc tatcgaaaaa aggattggaa
    31501 tcttcgattg actggttgtt ttgtgatcag cctgaagcat atgttttgaa acgtgcaact
    31561 gcgttgagtg taccggcaga ttgtttttca cctaaagaat ttgattcaaa aaaagagtat
    31621 gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg atttgatcgt attagctgga
    31681 tatatgcgaa tcattggacc ggtattgctg aaaaattatg ataaaagaat catcaatatc
    31741 catccgtctc ttttacctgc cttccctggt ttgcatggca tacgtgatgc ctttgaagct
    31801 ggagtaaaag aaacgggtgt cacaattcat tatatcgacc aaggtgtaga tactggacca
    31861 atcatccggc aggaaaaagt gagaattgaa caggaggaca cgttcgattc tttagaagaa
    31921 aaaatccata gagtagagca tcgaatctat ccagaagtga ttagtgaaat tattgaaaat
    31981 ggaggctatc tgaaatgaca agagcattga tcagtgtatc agataaaact gggattgtag
    32041 cattcgccca aggtttgatt gaacaaggag tagaaatcat ttcaacagga ggaacaaagc
    32101 atgcgttgga taaagctggg atcaaaacgc tttcgatcga agaagtgaca gggtttcctg
    32161 aaatgatgga tggccgtgtc aaaacacttc atcctaaaat ccatggtggt cttttaggaa
    32221 gacgcgatct ccctagccat atggaggcaa tggaaacgga aaatatccaa ccaatcgact
    32281 ttgtttgtgt caatttatat cctttcaaag aaacgattat gaaaccagat gtcgaaatag
    32341 cagaagctat tgaaaacatt gatatcggtg gtcctagtat gctccgtagt gcagcaaaaa
    32401 accatgaatt tgtcacctct gttgttgatc catctgacta tgaagaagta ctttcagaat
    32461 tacgtcagta tgggcatact tcactttctt tcagacaaaa actagcggca aaagtctttc
    32521 gtcatactgc ggcatatgat gcactgatcg ctcaatactt aacggattgg gtggaagaaa
    32581 aagaaccgga aaaattgaca cttacgtatg aacgaaaaca aacgcttcgt tacggtgaaa
    32641 atagccatca agccgctgcc ttttatcagt ccgctcttct ggaaaaatat tcgatcgcag
    32701 cagcaaaaca actccatggg aaagaacttt cttataataa tatccgagat gcagatgctg
    32761 cgctacggat catgaaggaa tatgacgagc caacggtagt cgccttgaaa cacatgaatc
    32821 cttgtggtat tgggacagca tctacgattt tagaagcgtg ggaagcagcg tatgaagcag
    32881 atcctgtttc aatctttggt gggatcatcg ttttgaatcg agaagtagat ctgccaacag
    32941 cagaacagat gcataagctg tttctagaaa tcatcattgc cccttcttat acacaagaag
    33001 ctttggaatt actgcaaaaa aagaaaaaca tccgattact gacagtagac tttgcgcagg
    33061 aagaaaatca aaatcgagaa gaaacggtct cagtcttagg tggacttctt gtacaagatc
    33121 aagatctggc aatagaaaat gaagaagagt ggaaagtcgt gacaaaacgt aagccgactc
    33181 cagcagaagc aaaagcatta gtgtttgctt ggagagctgt caaacatgtg aaatctaatg
    33241 cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg agccgggcag atgaatcgag
    33301 tcggttcagt aaaaattgcg attgaacaag cgcaagagaa aatggaaggt gcagttttag
    33361 ctagcgatgc ttattttcca atggatgatt cggttgaata tgcagccaaa catggtataa
    33421 aagcaatcat tcagccagga ggaagcatca aagaccaaga ttctattgat atggcgaata
    33481 aatacgatct agcaatggtc tttactgatg ttcggcattt tagacattag agaggagtcg
    33541 gataaatgaa cattttggtg atcggtgcag gtggtcgtga acatgcaata agtaaaaaac
    33601 ttttagccag tccgaaggtg gatacggtgt attgtgcgcc aggaaatccg gggatgacaa
    33661 aagatggtat caattgtgtc gctatcagtg agcgagatca ttcagcgtta atccattttg
    33721 ttaagaaaga ggctattgat tggagtatcg ttggtcctga agttcctttg ttaaatggga
    33781 tcgtcgatga ttttatggcg gaaggattga aaatcttcgg tccgacaaaa gcagcagctc
    33841 tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga tacttatcaa atcccgacag
    33901 ctaaatccag aagttttgaa tgttacgaaa aagcagcagc gtatatcaaa gaaaatggtg
    33961 cgccaatcgt agtgaaagcg gacggcttag cagctgggaa aggtgtagtc gtggctacca
    34021 cagtgaagga agcgctggat gcggcagaac aaatgttgaa ccagcatcga tttggggata
    34081 gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga agaattctcc cttttggcgt
    34141 ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca agatcataag cgggcatttg
    34201 ataacgataa agggccaaat acaggcggaa tgggtgctta ttcaccagta ccgcaaattt
    34261 caaaaaagat gattgaaaaa gctgtggaag aagttttaaa accagcggct ttgggaatga
    34321 aagaactagg acgctctttc acgggtgttt tatatgcggg tttgattgct acgaaggaag
    34381 gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc tgaaacgcaa gtcgttcttt
    34441 ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt attagagaat cgtacagtag
    34501 agttaaagtg gcagcaagaa ggatacaatg taggcgttgt ggttgcagct gccggttacc
    34561 ccgaagaata tgagacagga atggttctac cagattttct ggaagaagag ctttctgttt
    34621 actatgctgg agtttcctca aataacggca aactagttgg agcaggagga cgtctttatt
    34681 tagtagaagc atacggtgag acgatcaaag aagcacagaa aaaaatttac accgcgttaa
    34741 tggataaaac gacagatgga acattttatc gtacagatat tggagaaaaa gctgccaata
    34801 gcgaactgat cgtgaagtaa atcagctgct tccatttata aaaaatacaa caaacataat
    34861 cggaagcgcc gattttagtg aagccttttc ataaagagtg tggtacactt ttgttgtgta
    34921 tataaataag gaggagttca gatgaaaaaa attcaattag gtacttctga tcagaaagca
    34981 gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg aagatccagt aaaagtgatt
    35041 gagacagctt atgaaaacgg cattgatttt tttgaccatg cagatattta tggaaacggt
    35101 gaatgtgaag aaatctttgc agatgctcta gcaaaaacat caatcaaacg agaagatctt
    35161 tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt ttgatttttc taaaaaacat
    35221 atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa tggattatgt ggatgcttta
    35281 cttcttcatc gtccagatac attggtagaa ccagaggaag tagctgaagc gtttgatgaa
    35341 ttggaacggt caggaaaagt tcgttatttt ggcgtcagca atcaaaaacc aatgcaaatc
    35401 gaattgctga aaaaatatgt tcgtcaacca ttagtagcta atcagctgca atttggcttg
    35461 aaacatactg gaatgatcga tcaagggatt catgtcaata tgacagatga agcaagtatc
    35521 gatcatgacg gtagtgtact tgattattcc cgattgcatg atatgacgat ccaagcatgg
    35581 tcaccatacc agtatggatt ttttgaaggt gtatttatcg ggaacgaaaa attccctgaa
    35641 ttaaaccaaa cattagaaga actagcagct aaatatcaaa cgacaccaac tggcttggct
    35701 tctgcttgga ttttacgcca tccagccaat atgcaagtga tcgccggtac gatgaacgta
    35761 gggcgaatca aggaaatcgc tcaagcttca gaaattaata tgtctcggga agattggtac
    35821 gaattgtacc gtgctgctgg aaacatttta ccttaaagat tgtcataagc aggtcaaaag
    35881 ggctataaat taaaaagaca gaataacttg aaagctgttt tcagcttcga gatattctgt
    35941 ctttttttat tgcaaatgga aagagtatca ttgtacggat ttcgtttatt agttattttt
    36001 gtttttaagg aaaagctgtg tccgatattc ttttggagaa atcccttgtt ttttcttaaa
    36061 taaataactg aaatagttag ggtcattata accaatttca aaagcaatat ctgaaatacg
    36121 atagtctgat tgctgcaata atttttttgc taattcgatt ctttgttctg tcagataatc
    36181 gatgaatgtt tggttaaacg attgagaaaa aatcgtactg aaatgagagg gacttaatgc
    36241 aacttgttga gcgacccaag ttaaggacat atctggatcg gtaaaatttt ctttgataaa
    36301 atccaatgca tggttcaaaa ttggctgata tttgttcctt gaaggctgtg agggcagagc
    36361 agttaagaaa gaaatgaaca tataaactgt cgaacggtaa agcgagtcgt cggcgctgat
    36421 tgctaagcgt tgactggtgg atgtgcaatg aaccatttct tgcgggattt tcttttcttt
    36481 caggcagaca tgctggagta gcttagtcaa gacaaataaa cgatataatc gtgttcgagt
    36541 tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta gatacttcgt ttttcgataa
    36601 tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa tcaactggaa gtttcgcttc
    36661 ttgaatcaaa tcctcatagc tgataatttg ttctttaagg gaactggcgg tttcaagtat
    36721 catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt ctttctgcga caggaccaat
    36781 ggcgacagaa aaattatttt tttgtccctt ttctaattca tggaccaacg tttgggctac
    36841 ctgataactg gtctcgatca cattttcttc aagagaatca actattaaaa atttgatgaa
    36901 tcgagaggaa acagcagaga agatcacttg ttgattctcc ctaaataaaa acttcaaata
    36961 atcactgaga tgagcgtaat cttcaaagtc tgtactgact tggtttgctg ctaataatac
    37021 ggtcattttt ttccctgcta aagagcgatt gaaagattca gcaagtttca atgtttcact
    37081 gatcgtaagt gagcctttga acaaaccgtt caagaaatga ttttttttca attcgaaaac
    37141 aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct aaagcagtta ctgctttttc
    37201 tattgcttgt ttcaattcgc tacttttaat cggtttaagc agataatcat ctgcctgtac
    37261 ctggattgct cctttcatat aatcgaaatc gtcgaatcca ctaataaata tgagacgagt
    37321 ccaaggaagt agtttccttg cttcttttga aaaagtcaac ccgtccatga aaggcatttg
    37381 gatatcagtc agaatgatgt cgggctgtaa gtcgataatt gaagacagtg ccatctcacc
    37441 atctccagct tcgccgacat aagtgattgg ataataagaa ccaaggacag ttatttgttc
    37501 ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata aaaactttat acatgtttgt
    37561 ttcctccaat tgttttggga gatagaggga tcatcagtgt gacagttgtt ccttctcggt
    37621 atttgctgtc aatcgtgata ggtttttgat catttccgta ataaagaagg agacgcttgt
    37681 ttacgttgta aagtccgtag ccgatactga aatctgaatc gatccctttg gctaactctt
    37741 tacgtatttc tgccagtttt tctgcaggga tgccaatccc gttgtctata actttgaatt
    37801 ggatcatctc atcaattttg catgtggtaa tacgaataaa tcctttgtga cggacgtact
    37861 tcgttccatg gtatacagca ttttcaatca atggctgcaa gatcattttt aaaatagaaa
    37921 caggaaaaag tgtttctggt atatcgatct tatagtcaag catatggccg tatcttattt
    37981 ttaagatgac tagataatca ttgatatggc taatttcttt ttcaagagga atccagtctt
    38041 gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc atgggtcata gtcagagctt
    38101 cttcaaagca gtcttgttcg atcaaagaaa taatggcatc caaactgtta taaataaaat
    38161 ggggagtaat ctgagcttgc aatacacgaa cttcactttg tgctaaatgg tattgtttca
    38221 aagcgttctc ccgtaaagac tggtttagat cttccgccat tttattcatg ctagcggtaa
    38281 gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa gccaaggttc cctgaagaaa
    38341 gttgttctga catctcgatc agctgattga tcggttcttg gacctttctc tctaaaaagc
    38401 gacgattctt tttcgcatag aaaaaaatgg tactaagaac tccaagttcc actattgtta
    38461 atagaatgag cgagcggaca agtgtcgtat tttttttgct tgctaagtcg atctccacac
    38521 gaacaaaatc ttgtaagata tctgacagca gttgagtgac agaatctacc tgattgatga
    38581 tctcttcatt ggtatccata aaatcttttg ccaagatatt attgatcagc tcgttttgat
    38641 aatcttccag tgtatcgatc gtacgtagcg atacatctaa cgtactaatt tctttaagtg
    38701 tatttgtatt atttttgctc tctcgaatat cattcctaag ttcttctagg atattttcct
    38761 cattgaactc atctacggtt acttggccag aaatcaagtc ccacatactt tccaaaactt
    38821 tttgatcaac cttcaaagca attgcatctg ctttttggat atttgcgatc gtctgttgat
    38881 aaatcaaaag ctgttgcgaa tataacagta tgctcagtag caaagggata acagcaaata
    38941 gaagcatggc tttgtttgct tgggcaaaaa tctgttttat gcttaaattt tttgtcatga
    39001 tacttctcca gtcaataatt tctggttggg atgttagcta tattctgctg ggaaaagaca
    39061 gtctcggaaa taaaaatatc tttaggtaat gtttttcctg tttgaatatt tccaaaataa
    39121 cgagtaacgg tattggctac ataccagccg acatcaggtt tacactcgac tacacaattg
    39181 acgattcctg agcgtagctt ctcgatcata tcttcttgtc catcaatagt tacaatgatc
    39241 aaatcttctc caggtttgat tgatgtttct tttatcgcag ctaaagcacc gtgagtcatt
    39301 tcatcactat ggctgtataa tacatcgatt tcggataaat catttgtttc taaatatcgt
    39361 ttcatctggt cttttccttt catccgaata aaatcaccga caattcggtg aacaatagtc
    39421 atcggaggtt tatggtcgat ggttccatct ttttttaggg ttggtttacg attgattgat
    39481 tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt tctctgaacc agcaagttct
    39541 aggattctga tttcctgttt ctttgaattt gtgaagtgat tgctgacaaa taaacccgcc
    39601 cgatttcctt ctgctttgaa actggggcca atgtgggtga cgaaaagctc gggatcattc
    39661 gtttgaatat gtctgtcgac aagtatgaca gggatccctg ctcgctttgc ttcttttaat
    39721 acagagtccc acccggattc ttgcaaagga gtaaaaatga tcatatccac tttataggca
    39781 atgaacgtcc gtatatcttg gatttgccgt tcctgattca tgtagccatt tcggtagaga
    39841 acttggtaat cttctttttc aagcgcagtg ataattgatt cagtatgctt tttccgccag
    39901 ctactctccg ttcctgattg cgaaaaacca acgactagtg ggtcaggtgc ttcctttgta
    39961 ttaggtgtac accccatcat ttggtaagcg attacaacaa gggctaaaaa aaataaaaca
    40021 cgtttcactt taaatcactc catctggatt tgttagtact atcttatcag ataaaaggga
    40081 aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga aacttaaaaa aatccaagac
    40141 aaaaaaagta cacctaaaaa atttaaagta aatcccataa aaaaatcaat gttaacgctt
    40201 tctttattag ctatactcgg tgtatcaatt gaaatggggg ataaaaaatg aaaaacaaat
    40261 ttagaaagat tgttgggact atcgctattt tgaccgcaag cattctatta agtgcgtgtg
    40321 gcaattcagg atctgcagat gatagtacgg ggtatgtagg aatcgctatg ccgaccaaat
    40381 cagcagaaag atggatcgct gatgggaaca acatggtctc ggaattagaa aaactgggtt
    40441 ataaaacaga tcttcaatat ggagaagata aagtagaaaa tcaagtagca caaatagaaa
    40501 atatgattac aaaaggggta gatacacttg tgattgcttc tatcgatggt tcggctttaa
    40561 ctgatgtgtt agctaaagca aaagaagcag atatcaaggt gatcgcctat gatcgtttac
    40621 tgatgaattc agaaaatgtc gattattacg cgacttttga taattttgga gtaggtgtat
    40681 cgcaagcagc ttatattgaa gagcacttag gattgaaaga aggaaaagga ccattcacga
    40741 ttgaattatt tggtggctcg cctgacgaca acaacgcact aatcaattac aacggagtga
    40801 tgtctgtttt acaaccatat atggacaacg gtcagttggt cgtgccatct ggacagacga
    40861 gtttcagtca aatcgctacg cttcgctggg atggttctac ggcgcaagca aggatggata
    40921 atctgttaag cgcaaattat actgaccaaa cattggatgc tgttttgtcg ccatatgatc
    40981 caataagttt aggaatcatt tcgtcattaa aaggcgtggg gtatgggagt gaaagtaaac
    41041 ctttacctgt gattactgga caagatgcga cagttgctgg cgttaaatcg atcattgccg
    41101 gggaacaaac acaaacgatc tttaaagaca cacgtatctt agcaaaaaat acgattgaaa
    41161 tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa tgatactgaa acttatgata
    41221 atggggtgaa aactgtccct acgtatttag caaatacagt atctgtcgat aaagataatt
    41281 atcaagcaga gctgatcgac accgattatt ataaagaatc cgatctgaaa aattaagagg
    41341 aaccaaacaa ggaactaaag agatctaagt cagagagagg ataagaatta tggcggattg
    41401 tattttaaaa atggcagata tcaccaaaaa attttctgga atccgagcgt tagattgcgt
    41461 gaatctgatg attgaacgtg gggaaatcca tgcattgtgc ggagaaaacg gagcgggaaa
    41521 atcaacattg atgaatgtct tgagcggctt gtatccatat ggctcctatg acggggaaat
    41581 cttttatgat ggaaagctgt gtcaatttaa agatttgaaa gatagtgaag aaaaaggcat
    41641 cgtcatcatt catcaagaat tagcactaag tccttatctt tcaataaaag agaatatttt
    41701 tctcggaaat gaacaagcag aaagaggcgt gattgattgg gaactgacag aaaagaaaac
    41761 atatgaactg ctgaataaag tcggtttgtc tatcgacccg aatcttctag tatcccagat
    41821 tggcgtaggg caacagcaac tagttgaaat agctaaagca ttatcaaaat ccgtccgtct
    41881 gttgattttg gatgagccta ccgctgcatt gaatgaagaa gaaagcgcga atttgctgag
    41941 attgatccga gagttgaaag agcaaggtgt aacctccatc attatttcac ataagctgaa
    42001 tgaaatcgtg gatatcgcag atcgaatcac cattttacgg gatggacaga cgattgagac
    42061 actagaaaat gaaatgatca gcgaagagca tattattcgc ggaatggtgg gcagagattt
    42121 agttgatcgt tatcctgaaa gaaaaccgga tattggagaa gtttatttta aagtagaaga
    42181 ctggacggtc tatcaccctc ttgatcacga gcgaatcata aacgaccaca tcaacttgca
    42241 tttgaaaaaa ggagagattg taggaatagc tggactgatg ggagcgggca gaactgaatt
    42301 cgctatgagt ctatttggac attcttatgg aagcaagata tccggacgta tattaaagga
    42361 aggggcagag atatcagtta agaccgttcc ttcagccatt gcaaacggac tcgcttatgt
    42421 ctcggaggac cgaaaatctt taggactgaa tctgctgatg gatattcggg aaaacgtgac
    42481 gctgagcagt ttggataaaa taagtcaaaa aggagtatta gataaagaaa aagaagtaac
    42541 tgaggcagaa aatttccgga aaaagatgcg tataaaaaca aactccatcc atcaaattgt
    42601 cagtagtctt agtggtggga atcaacaaaa agtcgtttta tccaagtggc tgatgacaca
    42661 acccgatatt ctttttttgg atgagccaac ccgtgggata gatgttgggg caaaatatga
    42721 gatctacacg attatcgaag aaatggcagc aaatggcaaa gctgtctgtc ttatctcttc
    42781 tgaacttcct gaaatattag ggatgtgtga tcgaatctat acgatgaacg aaggacgtat
    42841 tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc ttgatgaaat taatgacgaa
    42901 agaagaggtg ggttaagttg gaacaggcaa aaaatcttac ggataaaaaa gagaaaaaac
    42961 taaatttgaa aagtagagca gctgatcttt ttggtcgcta cagcatggtg atcattttag
    43021 cgggactact tattgcgttt caattgatga cggatggtat tttctggcgt ccattgaata
    43081 taactaacct tgttctgcaa aatagccata tattagtact agctgcaggg atgttattag
    43141 ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt gatggcgttt gttggtgcaa
    43201 ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg gatgacagtt atcgcatgtc
    43261 ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg ggtagcttat gcagggatac
    43321 cggcgtttat cgtgacttta gcaggattgc tgatgtttcg tggactgaca caagttgttc
    43381 taggaggcca atctctagca ccttttccag ctgttttcca aaaaatgtct acgggttatt
    43441 taccagactt aagcgaagga agcagccttc acttcttgac attgatttta ggaatgatca
    43501 tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa tcgtcggaaa aatcatttat
    43561 ttgaagtgga atctccaaca gctttcttgg taaaggcggt atttacagca gtcgttgtac
    43621 taggaataac ttatatcttt gcctcttatc aagggtatcc gattattttg atcattcttg
    43681 gtttgatcgt tgcagcatat gggtttttga caaataaaac agtagcaggt cgacagattt
    43741 atgcgacggg cggaaatcga aaagcggctg aactatcagg gatcaaaaca aagcgaatca
    43801 cgttctgggt attcgtcaac atgggagtca tggcagcttt agctggatta gttttagctg
    43861 ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat ggaactggat gcaatggcgg
    43921 cagtatattt tggtggtgct tcgacttccg gcggcattgg aacaatcatg ggtgcgattg
    43981 tcggtggctt ggtcatgggt gtattgaaca atggcatgtc gattttaggc gtcggggtag
    44041 actggcagca ggcaatcaaa ggattgatct tgcttttagc cgttgtgcta gacttgtata
    44101 ataagaaaaa acgaacaacg taggagaacg ccggttattc agaaaaaaga ctgtgacaag
    44161 acatttgtca cagtcttttt ttcgctaaaa gcgaacattc attgtttcgt ttgtatagac
    44221 taaaaataat atatgttttt ttaccattcg tataaattct ctttttgctc ttgatttttt
    44281 tgcttaattg agttaaatta catagggcgc taaaaaaagc cttgattaaa ttaataatgt
    44341 tcgtgttttg ctggatgtga acatcaggag gataatgtaa tgaaagtatt tgattacgaa
    44401 gatattcaat taattcctaa taaatgtatc gtaaatagcc gttctgaatg tgatacaacg
    44461 gtcacattag gtaaacatac attcaaaatg ccagtagtgc ctgccaacat gcagacgatt
    44521 attgatgaaa caatcgcaga attcttagcg gaaaatggtt atttctatat catgcatcgg
    44581 tttgatgaag cagctcgaat tccgtttatc aaaaaaatga aaaagcgtgg attgattacc
    44641 tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta tagagaagtt ggcagaagaa
    44701 tcgctaaatc ctgattatat cactatcgac atcgcgcatg gacatgctaa ctcagttatt
    44761 gatatgattc agcatattaa aaaatatttg cctgaaactt ttgtgattgc cggtaatgtt
    44821 ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg cagatgcaac aaaagtcggg
    44881 attggtccag gaaaagtatg tattacaaaa atcaagacag gctttgggac tggaggctgg
    44941 caactggcag ctcttagatg gtgtgcgaaa gcagctcgca agccgatcat cgctgacggt
    45001 gggatcagaa cacatggcga tattgcaaaa tctgtccgtt ttggtgcgac aatggtcatg
    45061 attggttcat tgtttgccgg tcacgaggaa tctcctggcg aaacaaaagt cgaaaatgga
    45121 atcgtgtata aagaatactt tggttctgct tcagaattcc aaaaaggcga aaaacgaaat
    45181 gttgaaggaa agaaaatctg gatccaacac aaaggatctt tgaaagatac actagtggaa
    45241 atgcaacaag accttcaatc atctatttct tatgctggag gaagagatct ggaagccatt
    45301 cgaaaagttg actatgtcat cgtgaaaaat tcgattttta atggagacac aatctaaaaa
    45361 ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc attaagtaat aagaacagcc
    45421 aaacaaaaat agttctttat atgttttgtt tggctggaat tattatcgca gatacaagct
    45481 tttgaacatc attattcaga ataagggact gtgataagat ttttgtcaca gtcccttatg
    45541 ttttgcaaaa aaagtttttc ttttttctcg taaattcggt aaaatcaaaa gaaaaaatag
    45601 acaatagaaa agagaagctt atgtgggaaa aagtagagaa aaaacaagga ccgatttatc
    45661 gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg aaggatcaat cctggaagtc
    45721 aacttgaatc agaacgaaaa ctagggcaac tttttggtgt gaatcgttcc accgttgtcc
    45781 atgcattgga agagcttagg gagcttgggg tactaacgag caaacgtggc agcggatggt
    45841 ttgttaatca gactgaatgg gggaaattcg ctgttccaag aatcgattgg cggcaaatga
    45901 tctctcctcg ttatgagcag acggactggt atgagcaaaa aataagagaa gcaaagcaga
    45961 tccaaaaaac atcgtttctt gatttatacg ctagcgagat gccagatgag cttttgccga
    46021 attttgagtt tccttcttat tctcttgaag aaatcttagc ggaagaaaaa gaaatggatc
    46081 ttttaggcta tactccgtta cgtaacaaaa tcaaacggta tttggaaagt aaatttgaat
    46141 tggcattttc ccccaaccag cttcttgtga ctggtggcgg tcagcaagca atctttttga
    46201 ttttacaaac gattctttca gctggagagg ggatagctgt agagtcacct tctttttttt
    46261 accgattacc tcttttcaaa gcttcaggaa cgcgtttatt tgggataccg atggatgaag
    46321 aagggatcga cttagaaaaa ctgaaagaat cgatccataa aaataaattg aaagcagtgc
    46381 ttatcaaccc gaattttcaa aaccctacag gaaaagtgat gagtcaaaaa cgacgagaaa
    46441 agctagtaga attgtgtcga cagtatcggc ttccaattat tgaagacgat gtatttacgg
    46501 atctttcatt tctaaaccaa gaagaagtcc ttcctatacg aacgattgat ccggataatg
    46561 tgttatacgt cggttcgtta tctagggttt taggaaaaac aacgaaaatc ggttgggtga
    46621 taggacctga gacttttatc tcgcaactag ctcaagcgca agaaatgatg gagttttcga
    46681 tgaatatcct tacacaaatc acagtggcta atgtatttaa tgaagcaatt gatttgaaaa
    46741 tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact gataagcgct tggggagatt
    46801 cacaatcgtt tttcaagctt cattcaattt taggtggtta ctatgcctgg attacttggg
    46861 atgggaaaaa actagacccc gaactagcag aaaaagtagt agatatgggt cttggaattg
    46921 caccaagtct actttttggg caagatataa atggaatcag aatcaattac agtaggctgg
    46981 atgaaaacca aataccgttg ttttattcaa agatgaaaat tctagaaaag tggttaacag
    47041 aataatttca caaagtaaat agattaaaga atataacagc ttggatttaa atttcaagct
    47101 gtttcttttt tttcggaaaa agaatacgat ataaagaaac taagaaaaaa ccattatttg
    47161 tacgtccgtt cacgatgtgt aaataaaata aatgtttgca acaaaactgt ataacaccaa
    47221 cgtttttaaa tagaaacaga tggttgtaag tttgattaga aaatagaaaa aatgcagatg
    47281 aaatataaaa cgctttcctt attgtgattt tattcactaa tgctgttaat atgcggattg
    47341 gcataatttc ctttcatcgt gaaaatttgt gcttttagct tgtatttctc ataaatccat
    47401 gataatttat taatgaagac ggttaaatag tgatacagtt ttattcactg tttcaatcgc
    47461 agaatgaaga gattttctta tagatgagag aggaatgtgt gacaaatggc aaacaaaaaa
    47521 gcaccgatcg acttccaagc actgctagat gaagtcaatg cagatttccc agtatatcaa
    47581 gcacttgatc aagatggaaa cgtagttaac aaagatttag tacctgattt atccgatgat
    47641 gaactcgttg aattaatgac tcatatggta tggtctcgtg tattagacca acgttcaaca
    47701 gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa ctgctggaca agaggcaagt
    47761 cagctggcta gtgcttacgc atttgataaa gaagatgttc ttcttccagg ttatcgggat
    47821 gtacctcaac tagtaaaaca tggtttacct ttatctcaag cttttttatg gtctcgagga
    47881 catgctgcag gtaattctta tccggaagaa ttgaaagctc taccaccaca aattatcatc
    47941 ggtgcacaat atgtacaagc agccggtgtt gcattaggtt tgaagaaacg aaacaagaaa
    48001 aatgtcgtct tcacttatac tggtgatggc ggttcatcac aaggtgattt ttacgaagca
    48061 atcaatttcg ctggcgctta ccatgcaaat gccgtatttt atatccaaaa caacgggtat
    48121 gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa cacttgcaca aaaagctgtc
    48181 gcagctggga ttcctggtat tcaagtcgat ggaatggatc cgcttgcagt atatactgta
    48241 tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac cagtcctaat cgaaacactg
    48301 acttatcgtt atggaccaca tacactatct ggtgacgatc caacccgcta ccgtacaaaa
    48361 gacacagatg acgattggca gaaaaaagat ccattgatcc gcttccgtaa atatttgacg
    48421 gaaaaaggac tttggtctga agaaaaagaa gaacaagtca tcgaagcaac taaagaagaa
    48481 atcaaagcag ctattgctga agccgacaaa gtaccaaaac aaaaggtttc agatttcttg
    48541 aaaaacatgt tcgaagtatc tccacaatca atcaaagaac aaattgcaat ttatgaagcg
    48601 aaggagtcga aataatcatg gcacaaaaaa caatgatcca agcaatcaca gatgccttag
    48661 cacttgaact agaaaatgac gagaatgtcg ttgtttttgg tgaagatgtt gggaaaaacg
    48721 gaggagtttt ccgggcaact gaaggattgc aggaaaagtt cggagaagac cgagtattcg
    48781 atactccttt agctgaatct ggaatcgcag gattgagttt cggtcttgcg ttagaaggat
    48841 ttcgtccagt tcctgaaatc caattctttg gttttatttt cgaagcaatg gacgaagtag
    48901 tagctcaaat ggctcgtaca agatatcgaa tgagcggcac tagaaatcta cccatcacaa
    48961 ttcgttcgcc atttggtggc ggtgttcata caccagaatt gcattcggat aatttagaag
    49021 gtttgatcgc tcagtctcct ggtattcgag tagtgattcc ttccaaccct tatgatgcaa
    49081 aaggactatt gatttcttct attagaagta acgatccggt tgttttccta gaacacatga
    49141 aactatatcg ctcattccga gaagaagtgc cggatgaagc ttacgaagtt cctttggata
    49201 aagcagcagt tactcgtgag ggaacagatg tatctattat cacatacgga gcaatggtgc
    49261 gtgaagcaat caaagcagca gacaatcttg caaaagaaaa tatatctgtt gaaatcattg
    49321 atcttcgtac agttgcgcca ttagatgtag aaacgatcat tcaatccgtg gaaaaaactg
    49381 gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg cgttgccgcg caagtagttt
    49441 ctgagatctc agaacgcgct atcctttcat tagaagcccc aatcggacga gtttctgcac
    49501 ctgatacagt cttcccattt ggacaagcag aaaatgtctg gttgccaaat gcaaaagata
    49561 tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa gaagggacga aacaaagtca
    49621 tggcttatca atttaaattg ccggatatcg gtgaaggaat cgcagaaggt gaaatcgtca
    49681 aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta gaagttcaaa
    49741 atgacaaatc agtagaagaa atcccgtcac ctgttacagg aacggttaaa aatgtgattg
    49801 ttccagaagg taccgtagca aatgttgggg atgtattagt agaaatcgat gcaccaggac
    49861 acgaagacaa tgaaggggac agtggtgtag ccgcagaatc ccaaactcca gctaaaccgg
    49921 ctgctgaacc cactgttgat acagaatcag ctggatcgtc aagcgaagga gtcttccaat
    49981 ttaagttacc ggatatcggt gaaggaatcg cagaaggtga aatcgtcaaa tggttcgtca
    50041 aaccaggaga tacgatcaat gaagatgata cattactaga agttcaaaat gacaaatcag
    50101 tagaagaaat tccgtcacct gtcacaggga cagttaaaaa cgtgattgtt ccagaaggca
    50161 ctgtagcaaa tgttggggat gtattagtag aaatcgatgc tcctggacac aatagtgcac
    50221 cgtcaactag tgcgccatca gctgaagcac caaaagaaaa agtggaaaca tcaggttcag
    50281 caagtgtcgt tgaagctgcc gatccaaata aacgtgtatt ggctatgcca tctgttcgtc
    50341 aatttgcccg tgaaaaagat gtagatatct cacaagtaac tgcaactgga aaaggtggca
    50401 gagtaacaaa agaggacatc gaaaacttct tggcaggtgg tccaagcagt gcaccagcga
    50461 aatcagaagc gccagaagcg gcagcaccga aagaagcagc tcctgcagca gaaagcaaac
    50521 cagctgcacc agcaaaacca ttcaagtcca acttaggaga cttggaagaa cgtgtagcaa
    50581 tgacgccaac acgtaaagct atcgctaaag caatggtcaa cagtaagcat acagctccac
    50641 acgtgacatt gcatgatgaa gtagaagtgt ctaaactatg ggataatcgg aaacgattta
    50701 aagaagttgc tgctgcaaat ggtacgaaac ttactttctt gccatatgtc gtgaaagctt
    50761 taacagcgac tgttaagaaa tacccagtat tgaatgcatc tatcgacgat gcaaaccaag
    50821 aaatcgttta taaacattac tacaatatcg gtattgcaac tgatacggat cacggactat
    50881 atgtaccaaa tgtgaaagat gcagaccgca aaggaatgtt tgctattgca gacgaaatca
    50941 atgagaaagc aaaattagct catgacggca aactatctgc agaagatatg cgcaatggaa
    51001 caattacgat cagcaatatc ggatctgtag gtggcggttg gtttacacca gtcatcaact
    51061 atccagaagt agctatttta ggtgtaggaa cgattgcaca acaaccaatc gtaaatgctg
    51121 aaggcgaaat cgttgtcggt cgtgtgatga aactgtcatt aagtttcgat caccgtatcg
    51181 tagatggagc aactgcgcaa caagcaatga ataatatcaa acgtctttta gctgatccag
    51241 agctattaat gatggaagga tgataaacaa atggtagttg gagattttgc tgtagaatta
    51301 gatacagttg taattggtgc gggacctggt ggctatgtag ctgccatccg cgctgctgaa
    51361 atgggacaaa aagtagcaat cattgaaaga gagtatattg gcggtgtttg tttgaatgtc
    51421 ggctgtattc cttcaaaagc actgatagct gcaggacacc attatcaaga gtcactagat
    51481 tctgaaatgt ttggagtaac tagtgaaaac gtcaaactag attttgcaaa aacacaagaa
    51541 tggaaagaaa acaaagttgt ccatacgttg acttctggtg ttggtttcct attaaaaaaa
    51601 cataaggttg aaacaatcga aggagaagcg ttcttcgtag atgatcacac actacgcgtc
    51661 attcatccag attcagctca aacttattcg ttcaataacg caatcatcgc aacaggttcc
    51721 cgtccaatcg agattccagg atttaaattc ggaggacgtg tgttagattc tactggcgga
    51781 ttagcattga aagaagtacc taagaaattt gtgatcatcg gtggcggtgt gattggtgcc
    51841 gaattgggcg gagcgtacgc aaacttagga gcagaagtaa cgattcttga aggctcacca
    51901 caaattttac caacttacga aaaagatcta gtaaaattag tagaagatga tttcaagaaa
    51961 aaaggcgtaa cagtcgtaac gaatgcaatg gcgaaagaag cagtcgataa cggtgacagc
    52021 gtgacagtga aatatgcagt ggacgggaaa gaagaatccg ttactgctga ttatgtgatg
    52081 gtcactgtag gtcgtcgtcc gaatacagat gatatgggct tagaacaagc gggtgtcgaa
    52141 gtaggagaac gaggattgat cacggtggat aaacaaggac gtacgaacgt acctaacatc
    52201 tatgccatcg gtgatatcgt tccaggggcg gcattagcac acaaagccag ttatgaagca
    52261 aaaatcgctg ctgaagcaat ctctggcaaa aaagtagctg tagattataa agcaatgccg
    52321 gcagtagcct tcactgatcc tgaattggct tctgtaggta tgacgatcaa agaagcaaaa
    52381 gatgctggta tcgaagcaaa agcatataaa ttcccatttt cagggaacgg tcgggcatta
    52441 tcgcttggta aaacagaagg attcatccgt ctagttacga cgatcgaaga taacgtgctt
    52501 attggcgcgc aaatcggtgg agtcggcgca agtgatatgg tctctgaatt agctttagca
    52561 atcgaatcag gaatgaatgc tgaagatatc gccttgacga ttcatcctca tccatctctt
    52621 ggcgaaatcg tcatggatgc ttcggaatta gcattaggtt taccaatcca tatttgattt
    52681 gaataataca ggcgaaacgc aactgaaaaa tcagttgcgt tttgtttttt agaattatca
    52741 ataatattat tatgtaaact taaaaatatg acaacttctt ggtttattac cacttcctat
    52801 gctacactga agaggaatat gaaataggag agttgaagat gcaagaatat cagtatccac
    52861 ttgatttaga ttggacaaca gacgaaatgg tcattgtaat gaagatgtgg gaagatctgg
    52921 aacgtgcgaa tgaaaaaggg ataaacaatg aagctttttt gaagacttat cagcagttta
    52981 aaactgttgt caaatccatt ggtgaggaaa aacgattggg acgggaattt gaaaaagctt
    53041 ccggttattc tttatatcgt acagtgcagc aagcaaaaaa aaatccaaac aaaactttga
    53101 gaatgaacgg gtgagataaa tggaacagat gattgatcat atcaagtcct ggcttgaaga
    53161 agctggtgag aaaatcaaat cttctcaaca aacattaaca atctcgcaaa aatcaaatcg
    53221 aacggatcta gtaacaaatg tcgatcgaaa catccagaat tttctaatcg aaaaaatcca
    53281 ttcctttgat ccagaggcga aaatattggc agaagaagaa gggtgtaatc aattatcgga
    53341 tctcgatgga agagtcttta tcatcgatcc tattgatggc accttgaatt ttgtgattga
    53401 aggggaaaat ttttgtatta tgctcgctgt ttatgaatcc ggcgttggaa agcttggttt
    53461 catttatgac gtgatgagaa atgaactttt ttggggtgga aaaggaatag gcgtgtataa
    53521 aaatgatgag ccattgccta gaccagcaaa taaatcctta tcggaaggct tacttggtgt
    53581 gaatagttat cttttcggtc ataataaata tggaatccga gaaattgcgg aaagcagcat
    53641 ggggacacgt atgtacggat gcgctggtct tgaactagtg gcaatcttga aaggaaacca
    53701 cattgcttat atttcaaacc ttagcccttg ggattatgca gcgggaaatg tcttattgga
    53761 agagtttggt atggtaacaa gcggtctttt tggtactcct ttgacatttg aaaaaaggga
    53821 atactattta gcagggactt cttgtgcata tgcagaaatc gcagaccttt tgaaaaaaga
    53881 aggctgaaaa aaaggtagaa atcattcaca aaaatgataa aaacgagcaa aagattaatt
    53941 ttctcgaaaa aatgaaaaca ttttactata tttcatgaaa aaagtctgct ataattagca
    54001 gtcgagtaaa atttgccctg tcataaagaa ccaataaaaa aggagttagt tacattgaat
    54061 tatagaaacg atatccgtaa cgtcgcaatt attgcccacg ttgaccacgg aaaaacaaca
    54121 ttagttgatg aactattaaa acaatcagat acattagacg cacatacgca attgcaagaa
    54181 cgtgcgatgg actcaaatgc gctagaaaaa gaacgtggta tcacgatttt agccaaaaac
    54241 acagctgtag actataaagg tattcgcgta aacatcatgg atactccagg acacgcggac
    54301 ttcggtggcg aagtagaacg gatcatgaaa atggttgacg gcgttgtgtt ggtcgtagat
    54361 gcgtatgaag gaacaatgcc tcaaacacgt tttgtattga aaaaagcact ggaacaacat
    54421 atcacaccaa tcgttgtcgt aaacaagatt gacaaacctt ctgctcgtcc tgagcatgtc
    54481 gtagatgaag ttcttgaact attcatcgaa ttaggagcag atgatgatca gttagacttt
    54541 cctgtgattt atgcatctgc actaaatggt acgtcaagct tgtcagatga tccagcagat
    54601 caagaaccaa ccatggcacc tatttttgat acaattattg aaaaaatccc tgctcctgtc
    54661 gataacagcg acgaaccatt acaattccaa gtttcattac ttgactacaa cgattatgta
    54721 ggtcgtatcg gaatcggacg tgtatttaga ggaacaatca aagtaggaga ccaagtagca
    54781 ttaattaaat tagacggaac agttaagaaa ttccgtgtaa cgaaattatt tggtttcttt
    54841 ggactaaaac gtctagagat tcaagaagca aaagctggag acttgattgc tgtctcaggt
    54901 atggaagata tctttgtcgg tgaaacagtt actcctgtgg atcatcaaga tgcgttacct
    54961 atccttcaca ttgacgaacc aacattgcaa atgactttct tagttaataa ttcaccattt
    55021 gccggtcgag aaggtaaatt cgtaaccgct cgtaagattg aagaacgttt gatggcagaa
    55081 cttcaaacag atgtatcctt acgagttgaa ccaacaaact ctccagatgc atggacagtt
    55141 tctggtcgtg gagaattgca tttgtctatc ttgattgaaa acatgcgccg tgagggatac
    55201 gaattgcaag tatctcgtcc agaagttatt gaaaaagaaa tcgacggtgt aaaatgcgaa
    55261 ccgtttgaac gcgtgcaaat cgatacacca gaagaatata tgggtagtgt tatcgagtcc
    55321 ttgagcttac gtaaaggtga aatgcaagat atggtccata caggaaacgg acaaatccgt
    55381 ttgacattct taacacctgc ccgcggtttg attggttatt caactgaatt cctttcaatg
    55441 acacgtggtt acggaatcat gaaccatact tttgaccaat atctgccaat gcttcctggt
    55501 caaattggcg gacgtcacca aggggcgctt gtttcgatcg atacaggaaa agcaacgact
    55561 tattctatca tgagtatcga agaacgcggt acagtcttcg tagaaccagg tacagaagta
    55621 tatgaaggaa tgattatcgg ggaaaacagc cgtgataatg atttgactgt caacatcacg
    55681 aaagcaaaac aaatgacaaa cgtacggtct gctactaaag accaaacatc tgtcatcaaa
    55741 aaaccaaaac aattgacgtt ggaagaatct ttggaattct tgaatgatga tgaatattgc
    55801 gaagtaacac cagaaagcat tcgcttgaga aaacaaattt tagagaaaaa tgctcgtgaa
    55861 aaagcatcta aaaagaaaaa ataatctgta aaaggatgaa gagagaaacc agcttgttat
    55921 aaaaaatagc tggtttcttt ttttgtccaa ctcttttctg tggagaagtc atctttgtca
    55981 atggacataa attcagaaaa tacgccgaaa gacgtttaaa agacttttaa aaaacttatt
    56041 tctagagagt ttttgtttca taataagata atgtttcacg aaaggagatc aacttgtcct
    56101 tcgaagaaaa tcgaagtaaa atggcaagag aaaggagcgg gaagatgaac gacttattaa
    56161 aacaatactt tggctatgat gagtttagac ctggtcaaaa agaaattatc cagaaagtca
    56221 ttgatcagga aaatgtatta ggaatcatgc ctaccggaag tgggaaatca atctgttacc
    56281 agcttccagc tttactatta gatgggctta ctgtggttgt gtccccttta atctctttga
    56341 tgaaggatca ggtggacgcg gcgaatcaat taggtatacc cgccactttt atcaatagct
    56401 cgttagatgg ttacgaaaca gctagacgct tccaagaaat cgatagacag cagtaccgtt
    56461 tactttatat cgctcctgaa cgttttatca tgccggattt tatccaagca atgaagcgat
    56521 ggaacgtccg tatgatcgct attgacgagg cacattgtat ctctcagtgg gggcatgatt
    56581 tccgcccaag ttatttacag atggcgaacc agctagatca actgccaaat cgtcctgtaa
    56641 ttgttgcttt gacagctaca gcgactgtgc aagtagctgc tgacataaaa agacttttaa
    56701 aaattccaga aaacaaccat attcagactg gttttgaacg agaaaatcta cgatttcaag
    56761 taattaaaga tcaaaaaaaa gaacaatatc taatcgaata tttaaagatc aacaaaaatc
    56821 aatctggtat catttatgca gcaacgagaa aagaagtaga ccgtctctat catttgctta
    56881 gaaaattcga tttttccgtg ggtagatatc atggtggtct aaatgagaat gagcgaacag
    56941 aaatgcaaga agccttttta tacgatcgct tgcagctgat tgtagcgaca aatgcatttg
    57001 gtatgggtat aaataaaagc aatgtccgtt ttgttatcca ttatcaaatt cctggctctc
    57061 tagaagcata ctatcaggaa gctggtcggg cgggaagaga tggtctttcc agtgaagcca
    57121 tcctgctttt ctctcctcaa gatatccaag tccaaaagtt ttttatccag cagtcccaaa
    57181 gagaagaagg gcaaaagcaa aaagaatatg aaaaattaaa agcgatgaca gaatacgtgt
    57241 atattgagtc ctgtcttcag caatacatcc taaactattt tggcgagaca agcagtccgt
    57301 gcaaccgttg tggtaactgt ttagatgaca gagaaatagt agaagtaacg acagaagcac
    57361 agatggttct ttcttgctta aaacgtatgg gtgagaacta tggtaaacaa atgctgatga
    57421 aagtcttagc aggatcgaaa gaacaaaagc tgcaagcttt aggttttgga catttatcta
    57481 cctatggact gatgaaaaac caatcgcaaa aagaaacgat gcagttaatt gaatatttga
    57541 tatcgaatgg ctatcttctg accatcaatg gtgagtatcc tgttttgaaa gtaacagaaa
    57601 gagggataca agtattgaaa ggacaagaat ctgtttatcg aaaggaaccc aagaaagtcc
    57661 agcagctatc ggatgaagaa accgatacac tatttgaagt gctgcgggaa ctgcgaacgg
    57721 atctagcatc agaagcaggc gttcccccgt atgtcgtatt ttcagattcc acattgaaag
    57781 aaatgagccg aatacgtcca tcaagcagat tggagatgct tcagataaaa ggagttggcc
    57841 aaagcaagct tgataaatat ggcgaagcct ttttatctcg gataaaaaat gcggactcta
    57901 acgttctgga taagtagaaa gaacgaatac gtaaaaatga ataaaaacaa ctggttaaat
    57961 ctgttttttt tgctccttat gaaaatcaaa tatgttataa ttaaggaatt agaatgggag
    58021 gtaagcacag atggattctt tgtcgaaaaa acttgcgatc caagtattaa atgatgaagc
    58081 agaacggatc aaacgattaa tccgaaatca aaacaacagt ctctgtatct cacaatgcaa
    58141 agccttcgaa gaagtggtag atacacagat gtacggcttt tcccggcaag tcggttttgc
    58201 tgtccgtata ggagtaatcg gaaagaacga gggccagctg atgttaagtg agctagaacg
    58261 agaattgaat cagttatata gtgaggttta ccaagaaatt tatgataaaa aagaagttgg
    58321 caaggaggaa tagacttgcc taagaaagtg aaaaaaaggc atctattaga ctatagcatc
    58381 ttgattccct atttaatttt atgtgtattg ggattgatca tggtatatag ttctacgtcg
    58441 tatctattat tagaaaacgg acaaaatccg tccgcatcag tcattaacca gagtattttt
    58501 tgggtgctta gcttgattgc tatcgcacta ctttataaaa tgaaaacaga tgttttgaaa
    58561 aaccagcgtt tgatcatggc agccatcgca gttttgacga ttttgctgct gattgttgtg
    58621 ttttttggta aggagatcaa tggggcgaaa ggttggctgc aaattgcagg attctcgatc
    58681 caacctgccg aatacctaaa aatcatttct atctggtacc tgtctctgac tttatctaaa
    58741 agacaaaaca gtgtacaaaa agattttctt gggactgtga aacgtccact tgcaatggtt
    58801 atcggactta ctgcattagt cgctattctt cccgattttg gtaatgcggc agttatcttt
    58861 ttgattattt tggttctgct tttagccagc ggagtcaatt atgtgtatac tttgattgta
    58921 ggagtaggag gcttttgtct aagtactttt acgatctggc tgatcaatat cacaaacgga
    58981 aagatcttac ccggacgttt acagtatatc tataatcgat ttgctattta ccaaaatcct
    59041 ttctcagacg aattaaataa agggcatcaa ctagtcaacg gctactatgc catgttcaac
    59101 ggaggactat ttggcagggg attaggtaac agtatccaga aaaaaggatt tttacaagaa
    59161 gcacaaaccg attttattta tgcaatcgta gtggaagaac tgggagtgat tatggggatt
    59221 ttgatattag cgttgctatt ctttatgatt gtgcgcattg tccttgtagg tatccgttca
    59281 aaagatccgt tcaattcgct tttgtgcatt gggatcggcg caatgttttt gatccaagta
    59341 tttgtcaatc ttggagggat tactggcgtt attcctttga cagggatcac gttcccattt
    59401 ttaagtcaag gaggctccag tttgctgatg ctttcgattt gtgtcggctt tgtcctcaac
    59461 atcagtgcgg atgaaaaacg caagagctta ggtttataat aaaaaaagat gtaggagtgg
    59521 ttcgatgaaa aaagttttag ttgctaacag gggtgaaatc gctgtacgtg tatttcgtgc
    59581 ttgtacagaa ttaggaatta aaactgttgg aatctatgca gaagaagatg aatattccgt
    59641 acaccgtttc aaagcggatg aagcatattt agtaggacaa ggaaaaaaac cgattgatgc
    59701 gtatctagat attgaaggga tcatttctat cgcgaaagaa tgcggagctg acgctattca
    59761 tccgggttac ggtcttttgt cggaaaactt gaattttgcg caacggtgcg aagaagaagg
    59821 catcattttt gttggaccca aactgcatca tttagatatt tttggagata aaatcaaagc
    59881 aaaagctgca gctatcgaag cggggattgc ttcgattcca ggcacagatg gaccaatcgc
    59941 ttctatagac gatgccttgg agtttgcgaa acaatacggt tatccgatta tgatcaaggc
    60001 agctctaggc ggcggcggac gcggcatgcg tgtagctcac gatgaaaaga gtgcaagaga
    60061 gggctacgaa cgtgcgaaaa gcgaagcaaa agcagccttt ggtagtgatg aagtgtatgt
    60121 tgaaaaatac atcgctaatc ctaagcatat cgaagtacag attctcgggg atacgcatgg
    60181 aaacgtcatc catctttttg aaagagattg ttctgttcag cgccgtcacc aaaaagtagt
    60241 agaagtagcg ccttgtgtct ctatgaatga acagcaacgt caaaaaatct gccaggcagc
    60301 tgtccaattg atgaaatatg tcgggtatgt caacgcaggt acagtagaat ttcttgttga
    60361 aggagatgat ttttacttta tcgaagtcaa ccctcgcgtc caagtggaac atacgatcac
    60421 agaaatgatt acagatattg atatcgtaac aacgcaactg ttgattgctc aaggtttgga
    60481 tctgcataaa gaaatcggat tgcctcagca agaaggaatt aaattaaatg gttcagccat
    60541 tcaatgccga atcactacag aagacccgtt gaataacttt ttaccagaca cagggaaaat
    60601 cgatacgtat cgttcacctg gtggttttgg cgtacgtctg gatgtcggaa atgcttacgc
    60661 gggctatgta gtgacaccgt attttgattc attgctagta aaagtatgta cgcatggtgc
    60721 tacctttgaa acagccattc agaaaatgga acgttgcttg aaagaattta gaatccgtgg
    60781 agtgaaaaca aacattccat ttatgctcaa tgtcatcaca catcctgaat tccaatcagg
    60841 aaatgcaaaa acaaccttca ttgatagtac agcaacatta tttgaatttc ctcgactacg
    60901 agaccgcgga aacaaaacga tgaaatatat cggtgaaatt actgtgaatg gttttccagg
    60961 tatcgaaagt ggcgaaaaac cattttatga agaaccacgt atgcctaaag atctaatcac
    61021 aagaactgat tacgtaacgg ctaagaatgt attagatgcg aagggtgccg atgctttggt
    61081 cgaatggatc aaaggacagg aaaatttgtt gttgacggat acgacattta gagacgccca
    61141 tcaaagtctg ctagcaactc gtgttcggac aaaggatttc aagcagattg cacgtttgac
    61201 tggagaaggt cttcctgaac tcttttcaag tgagatgtgg gggggagcaa catttgatgt
    61261 ggcttaccgc tttttgaatg aagatccttg gcaacggttg agaaaaattc gttctttaat
    61321 gcctaatacg ttgctgcaaa tgcttttcag aggttcaaat gccgttgggt attctaatta
    61381 tcctgacaat gtattggtgg aatttgtcaa agaagcagca gcgcaaggaa tcgatgtatt
    61441 tcgaatcttt gatagtttga actggactcc acaaatggaa aaaagtatcc aagctgtacg
    61501 ggatactggt aaaatcgcag aggcagctat ttgctatact ggcgatatca acgatccaag
    61561 tcgggcaaaa tacaatgttc agtattataa agacatggca aaggaactag aacaactggg
    61621 tgcgcatatc attgcaatca aagatatggc tgggctgctt aaaccgcagg cagcttatcg
    61681 tttgattagt gaattgaaag aaacgacaga tctgccaatc catctgcata ctcatgatac
    61741 cagcgggaat ggaatcatca cttattctgc tgcttcaaaa gcaggagtag acatcgttga
    61801 cgtggcaatg agtgcaatga gtgggaatac tagtcagcct agcatgagca gcttgtatta
    61861 tgcactggtc aatggtccac ggctgccaga aatcacgatt gaaaatgcac agaaattaaa
    61921 ccattattgg gaagatgtgc gcatgtatta caaaccgttt gaaaacggct tgaatgctcc
    61981 tgaaacagaa gtatatatgc atgaaatgcc aggaggacag tattcgaatc tacagcaaca
    62041 ggcaaaagct gtcggattag gtcatcgctg ggatgaaatc aaacaaatgt atcatactgt
    62101 caacttgatg tttggcgata tcgttaaagt aactccatca tctaaagtag ttggagatat
    62161 ggcactattt atggtccaaa atgatcttac agaagaagat atttatgaaa aaggcgaaac
    62221 actaagtttc cctgaatctg ttgtgacttt cttccaagga gaactagggc aacccgttgg
    62281 cggatttcct aaaaaattgc aaaagattat tcttaaaggc agacctgcat tgaatgaacg
    62341 tccaggtctt ttggctgaat cagtcgactt caacgaagta aaaaaagaat tggcagaaaa
    62401 aattggctat gaaccaaaac aagacgaagt attaagctat ttgatgtatc cgcaagtctt
    62461 tttggactat caaaaagcat ataatcaatt tggcgatgtt acattactgg acacaccaac
    62521 atttttccaa ggtatacgtt tgggtgaaac aatcaatgta caaatcgaac gcggaaaaac
    62581 gcttatcatt cgtttagatg aaatcggaga acccgatatc gaagggaatc gcgtactgtt
    62641 cttcaatttg aatggacaaa gacgtgaaat cactatcaaa gataattcga tcatcagtac
    62701 ggtccaaacc cgattgaaag ctgaaccgac aaaccgagaa caaattggag caacgatgtc
    62761 tggttctgtt ttggatgtat tagtgaaaaa aggcgataac gttaaaaaag gtgatacgtt
    62821 gatgattact gaagcgatga aaatggaaac ggccatcgaa gcacgttttg acggagaagt
    62881 cgcacatgta tatgtgtctt caggagacac tatttcgtct ggtgaccttt tgattgaagt
    62941 gactgagaaa taataagcga aaggtgggga aacatgaaaa gactgggttt gttttggctg
    63001 attctgctat tagttattgt ggcattctac atggaaccag tcttgtttcc gccaaaactt
    63061 gaagtgaagg aaaactctga tcaacaaata tcaaaccaaa tgacaacgtg gaaataccag
    63121 gagcttaaag caactggttt ttctacttat atcggaaaac cgatcgatca gctggaaaag
    63181 gattttggcc aagcctatga tcgattaact agcggatttg gttttgaaac aagatattat
    63241 gaaaataaag ctagtcatct cacatttgaa gcgaacatcc aagacagcag agtcacaact
    63301 gttaaagtac tgcaaacagg gcctgctgat atcgcgccgt tttatttagg gatgacgatg
    63361 caagatctta cgaaaatcac tactatctat actaatttca cttttgagta ccatgataca
    63421 gaagttggaa tcgaactaat ggaagaggat atgaattatc gtccgctaat tgcttttgat
    63481 aacgacactt ttgctatttt attttttgat caaacaacaa acggcctatt ttcagttgtg
    63541 tatttagata aagatagtct tttgaaacta ttgccatatc aagtgtttgg tgaaggcctt
    63601 ccacattatc aagcagataa atcggctgat tgggaatcaa tcaatcgcgt taaagaacga
    63661 aaaagtacga ctttattaaa tatgcttaga agagaagacg aacttcccat atacaatcaa
    63721 acacttgcct ttcaaaacca cagtcagctg ctactacatg attttttgac aaggcctgag
    63781 gaaatattgt cagaggaacg tatggctgat tggcaaaaat cgctaggcag tgctcaaacg
    63841 acagtgaaat tctcactgac gaatgatgaa ttggagaagt taatcagtaa acaaaaatta
    63901 gaaaatacta gtgggctatt tattcatccg gcgattgacg ctactttttc gtttttatat
    63961 tggtacagcg atccttacaa ccatgaccgt ttcatggacc cgggaacgga ttctgtaggc
    64021 attgcttttt ctaaagaaaa tatgttagtc ttattgcaag aagaaaacgg agaaagtagt
    64081 gatagcagtg atcgttaacg aagagctgtt tcaactggag gatcaatgcc tccaagtcgc
    64141 tgaaatgata aaaaagagta aaacgatggc ttcttatctt gaacataaac agtcaatgga
    64201 agaatctgca aaagtttgcc agttgaaaga agcgttcttg tctaagaaag aagcatttga
    64261 aaatgtagcg gcatatggtg agtatgcacc tgattatcgt gaaaaaaaac gagctgttcg
    64321 aaaagcaaaa agacagcttg atatggatga gcatgttgca gctttccgat atagtgaaac
    64381 acagctgcaa agtctgttgg atcaaattgt ccaagtactt gccgaagaag tttctaatga
    64441 aatcaaagta gatgcaggta gcccgttttt tgaaacgaaa aaacactttg gatgcggagg
    64501 taattgtcat gcaattagac aatagtgaat ttgaaataac aaaacgacgc gggctgatcg
    64561 tatgggtcta cagcttaaaa caattaaaga atctgaaaaa gttcggcttg ttgcattatg
    64621 tctcaagaag aatgaaatat gtcgtgcttt acttaaatga agagacattg gaagaaacag
    64681 aagaacgaat ccgtaaatta cattttgttc gaaacgtaga acgttcttac cgaccggata
    64741 tcgaaatgaa ttttgccgaa aaaataggaa acaaaacagt attaaaagac gaaggtttcg
    64801 aaattgaaga gctaaataca gaaatccgat tagctgaaca tctttaaaaa tctcttatga
    64861 gcagttttta aataaaaaat aacttggata acgatcgatt tttgatcatt gtccaagtat
    64921 ttttttggta tactagtacc agtaccattt ctaaggagtg agtagatgcg gataatatca
    64981 ggaaattatg gcgggcgccg tttaaaaagt ttagcagggg cgaacaccag accaactaca
    65041 gataaagtaa aagaatccat attcaatatg attggaccat attttgatgg agagacagta
    65101 ttggatctgt ttgcaggaag cggtggttta gctatcgaag cagtatctag aggctgcagt
    65161 catgcggtat gcgtagacaa aaattaccaa gcgctaaaaa tcatcaaaga aaacatcgaa
    65221 attacgaaag aaccagagaa atttaccaca ataaaacttg atgcggacaa agcaatcgaa
    65281 cggctagcag cggagaaaca acaattcgac tacttgtttc ttgatccgcc atatgcaaaa
    65341 caaaaaataa tcgatcaaat ccataaaatg gaagaactgg gacttttttc taaaaccgca
    65401 gttatcgtat gcgaaacgga taaaacagtc gaattgccag aaactgtggc tggattccat
    65461 caaataagaa aacagattta tggcataacg gccgtaacta tctatagaaa agagggaaat
    65521 caatgaaacg tgcattattc ccaggaagtt ttgatccttt tacaaaaggt cacttagata
    65581 cggtggaacg tgcggctaaa ttattcgatg aggtagtaat tggtgttttt atcaatactt
    65641 caaagaaaag tttgtttccc ccagaagaaa gaatgacatt gatcacaaaa gctgtttctc
    65701 atcttcctaa tgtaaaagtc atgcatcaag aaaatcaatt gacggtagaa acagcaaaag
    65761 agattggtgc agatgcgttg atcagaggca tacgaagtat caaagacttt gaatatgaac
    65821 gagagattgc tcagatgaat catcatctat atgatgaatt ggaaactgtc ttcttattag
    65881 caaaaccaga atatagtcac gtgagttcca gtattttaaa agaagtactg cactttggcg
    65941 gagatgtgag cagctactta ccgccagtga tcaacgaagc tttagctgga aagcgtgaat
    66001 caaatgaaag ctaaacaatg gttgaaaaca gtactgatta tcatatttgg aatgttgatc
    66061 attggatttg tagtagttcc cttgccgtat tatgtagaat caccgggagc cacgatcgat
    66121 ctgaaagaac taattacggt caatgataag gaagataaag gttctgggtc tttctctctt
    66181 acctctgttg gtatcaggca agctacaggt ttcttagctt taaaagctaa aatgacccct
    66241 tttgaagaat tgatcagtga agaagaattg actggtgggg cgacaaatga agaatataat
    66301 caaatgcaac agtattatat ggattcttcc caaaatgcag caatcgaaca agcgttaaaa
    66361 cttgcagaca agccttataa aatggaattc aaaggcgtat atgtcatgag tgtagagaaa
    66421 acatcgaatt tctttggcaa gctttcagtt ggagatacag taacaaaagt agacgggaaa
    66481 agctttcaaa gtacagaagc atttatggat tatgtaaaaa gccaaaaagt tggacaaaca
    66541 atcgaaatca gttatttgca taatggtgaa gaaaaaacag cttctggtga tctgatcgag
    66601 ttaccaacag ataaaaaggc aggaataggt atcacgctta ctgaccatac cgagatcgaa
    66661 tcagatacag atgttcgtat taattctggc tctatcggtg ggccatcagc gggattgatg
    66721 ttcactttag aaatctatga acaagtcact ggtaaaaact tgcgacatgg taagcaaatt
    66781 gcaggaactg gaacgatcaa cagtgaagga gaagttggcc gaatcggagg aatcgataaa
    66841 aaagtggcaa gtgcggataa agctggcgta gagattttct ttgcaccaga tgatacgatt
    66901 tcagacgatg ttaagaaaga atatcctgaa ataaaaacca actacgaaga agcaaaagct
    66961 gccgctaaaa aattgaattc ctcaatgaaa atcgtaccag taaaaacagt acaagaagcg
    67021 cttgactatc tagagaaaat gaaatgaaac taaataatta aagaggggtt gtgacacgag
    67081 ttctgtcaca acccctcttt ttcgtcaaaa atcttcacga taaaaataaa aacaaaagaa
    67141 aaaattgacg taattagatg ttgaagggac gattttgcca gagctcactg tttcttcaat
    67201 tttaaatgaa aggagtaatg aatgattttt actggtcatt ctttgaaaaa agaacaatga
    67261 tagaaaaaat cagcaagaaa atactagctt cacccaaatt gatcatttgg atgtctatga
    67321 tagttcttat cttttgtatc gcaagtggtt ttttattatc aaatttgcta ttttatagag
    67381 aaacagaaga gactgctgca aaagaaatac tttcttcgtt tagttccagt ggagaagatc
    67441 catcagctga aggaaacgat gtagaagagg atgctcgtcc aaaggtcatg tacaccgata
    67501 tcaaaggaag tgtgaaggag cctggtatct attccttttc ttcagaagaa cgggtctatg
    67561 atgtactaaa gcgtgcaggt ggattattag aagaagcgga tagcgatcga atcaactttt
    67621 ctgcgaagat agaagatcag caagtcctat atatccctgc tgtaggtgaa gagctgccag
    67681 aacatcttga tcagttggca tcctcggaag gaaaacagcc tacagcagat tccgagcctc
    67741 ccaaaataaa tatcaataca gccactccat cagaacttca gcagattcct gggatcggat
    67801 cagtcaaagc gcaagaaatc attcgattta gagaagaaaa cggatccttc cagaaagtgg
    67861 aagacctgca ggagatttct ggtatcggtg aaaagacagt tgaaaaacta aaaaacttcg
    67921 ttacaattaa atagaatgat tcaaaatcga ctggcacgag caataaatgg acgctaatgg
    67981 atactaagaa taatccaatt ctaagagctt ggcaggacga ggaggtagta tttttggata
    68041 ggaaatagct tgattgttcg caaagaaaca ttaaaaaaac caatgctgaa tgtctatctc
    68101 caaaataaaa tatctgggat tcatattatg aatacggctg tcagcggcaa taacagtcaa
    68161 gctctacgag aacgctttgc caaagatgta cttagctata cagcagataa agtatttatt
    68221 ctcattggga cgaatgatct agcagagcat aaacaacttt ctaaagaaac gtaccaaaaa
    68281 atctgcagtg gatgatagtt cagctgaaaa aagactatag ttctgatcat gctttcttta
    68341 tcacgccacc agcagtcgat gagacaaaac aaaaatatcg gaataacaag ttgatcaaag
    68401 aatatatctc tgttctcaca gaagtagcaa aacgccatga ttgtgaagta tcgattttta
    68461 tacggaattt cttgaacaaa tggattcgaa gaatttttat aatgggctaa tggatgacgg
    68521 acttcatttc ggcagtgaag ggtaggatct tttgtcagac aggatgattc gttatattta
    68581 aagaatattt tgtttaagca atgagtactt tttaatcaac ttgaaaaaac ggaggaatat
    68641 aaaacatgtt agaaaaatct tcaaaagcat gcgatacgaa taaagaaaaa gttactgata
    68701 agtcacataa tgaacgcatt ccttgggacc agtactttat ggctcaggca gtactgttat
    68761 ctttacgtag tacgtgtaca cgtttagaag taggagcgac actcgttcga gaaaaaagga
    68821 tcattgctgg cggctataat ggagcagtca gtggagatgt ccactgcata gatgaagggt
    68881 gttacgtcgt ggatggacac tgcttgcgaa cgatccatgc agagatgaat gcactcctac
    68941 agtgtgcaaa acttggtatc ccgacggaag gttcagaaat ctatgtcaca cattttccat
    69001 gtttggcctg tacaaaggct ttgttgcaag ctggtgtgaa agggatcaat tatctccatg
    69061 actatcgaaa tgatccttat gcccaagcgt tgatcgaaca attaggtgta tctgtacacc
    69121 aagttgcttt agactcacag catttttcaa aacttcaaaa tgaattaaca ggaaaacatg
    69181 tctagcgttt tagaaaggca tgttcgaaat cggttgattt ttccggcaat tacgtcgatg
    69241 attatctgtt tgttgtatta cactgacaat tggggttatc gtttgcttct tgccggaatt
    69301 tttttatggt tttcgctaaa agaaggacgt tttatcgcgt acttgtgtat tttgtgtagc
    69361 ataacggtat ccatttctta taggctacaa gagtattcat ttttagagga aaaaacaaca
    69421 tctgcgcaaa ttactgtatt tacagatacg attcgtgcaa atggtaattt tttgacaatg
    69481 gaaggaaggt tatcagagaa taaacaaaag ctccagcttt cttatcaagt aaacacagaa
    69541 gcagaattga aaacatggct taacttccga ggaaagggaa tagaattgac tgctgaaggc
    69601 gagttcatct ctccagcaaa aaagcggaat ctttataatt ttgaccaaga agcttacttc
    69661 aggaaccata gaatttctgg acggttccaa attcaaaaga ttgaacagat caccatgcaa
    69721 aatcactggc gaaactggct tcagagaaaa agaggatctt ttatctcctt tgtccaatct
    69781 gaatttccgc aaaaaacaag tgtatatatt aattctttat tatggggcta taaagatgca
    69841 ggattcagag aaccagaaga aatttttagg gagagtggtt tgctgcatct gttcagtcta
    69901 tcgggtctac acatccaatt ttatttaggg tggctgtatt atttatttcg acgtatcgga
    69961 tggccactac acgtcagtat tattccgttg agtctactaa ctatctgtta tgtttctatt
    70021 gcaggaagtt ctatttctgt tttgcgtgct agtttgctgt ttttattgcg attgctagtc
    70081 aaattgctga ataagcatta ttccaccatg gacttatttg cagttgtctt ttggcttctt
    70141 ttactatttg atcctcgatt tctttttcat gcgggtggac agcttagttt tttcatgagt
    70201 tttttgttta tcctgatttc ttttgatgga gattggttga aaaaaacggc ctctcacgtc
    70261 ctgtttacta tgatcacgat gccgttgatt gtatggcatt tttatgagtg gcctatttta
    70321 ggtagtcttt ttacattact gattgcaccg gtattcaagt ttctttttct tcctggtgtg
    70381 ttatttctca cactcttcaa tcgctggctg ccggaaactt tacttttgct gatagaagag
    70441 ggattaatct tatttgagcg aataatcgat ttttcttcag ggtcgtctct cattatagga
    70501 cgtttgcccc ttgtgctatc tgggatgtat attttcggat tactgatttg tatggatagg
    70561 ttgaaagaac aacctgtgaa acacttgttt tatgttggtc ttttttcttt tatttttttg
    70621 actttgccat ttttacgctt ttcttcaacg atcgctttta tcgatgtcgg tcaaggagac
    70681 agtatctttt tgcaaagtcc ttttcgaaaa gaaacgattt tgatcgatac tggaggtcag
    70741 ttacactttg aaagagaaaa gtgggcgcaa ggtatgatac gtcctcctgc tgaaagaaat
    70801 atcgttccat atctaaaagg tcaggggata agtgtaatcg ataaactcat cttgacacac
    70861 gacgatacgg atcatgtggg agaattaccc acgttatctc agcattttac tatcaaaaaa
    70921 atttatatcg gttggggcgc tggacgaaat gagccattac aaaggcattt atctgaagct
    70981 caaaaaaatg gtactgagat cattgaaatc aaacatgggg acaggatcag cggttattat
    71041 gatctttatg tattgactcc ttttgaaaag ggagagggaa gaaatgaaga ttcgattggt
    71101 ctatggatgg aatataacaa taggcgcttt ttatttttag gagatttgaa tcaagcaatg
    71161 gaaaaacaat tgcttttgat ttatcctaat ctgaaagccg atgtagtcaa attaggtcat
    71221 cacggtagcc gtacgtcaag taacacagat tttctttccc atattgaagc aaaacatggg
    71281 attatatcct gcggcgtaaa taatcgttat ggtcacccgc acagcgaagt attggagaca
    71341 ctagaagaaa atcagataaa aacatggcga acggatcaac aaggaatgat cacctatcgc
    71401 tggcatccag tttttcatcc tcatgggcta gtggaaacaa tgatagacta gtaattctca
    71461 tctgctcatg gtaggataat ttttgaaagt ggtgagtaat ttgagtatac aagcagagtt
    71521 acaaaaaata cgtaaagaaa aacttgcatc ttgttacttg attttaggaa cagaaaagtt
    71581 tctccaagat caagttcgga cagaaattgt caaaaaaatc caattagagg gcgaagatga
    71641 cttaaatttt ttaagttttg acatggaaaa tgcaagttta gatgaggtag tagctgaagc
    71701 agagacgttg ccgtttttcg gagatcaacg gttagtattc gtagagaatc cttatttttt
    71761 aacaggtgaa aaagtaaaca atggaatcga acaaaatact gatttattga cggcttattt
    71821 gaaagaacca ttagaatcga ctgtattagt attctttgcg ccatatgaaa agttggatga
    71881 acggaaaaaa gtaacgaaac aattgaaaaa aacagcaatt atcatcaatg tccaacagtt
    71941 gaatgaaaaa gaagtacgtc aatatctgat gaatacctta gagaattcct caatcaaaat
    72001 ggaacgaagt gcaattgatt tattcttgag gttgaccgac ttagatttat ccaaaatgat
    72061 gagagagtta cagaaattgg tcctttatgg acaaaatcaa cagcaaatca cggtaagaga
    72121 agtagaagaa ttagttccta aaacgttaga acataatatt tttgacatga cccaatatat
    72181 tttaaaaggg aagacggaac aagctttgcg tttatacgaa gatttagtta tgcaagggga
    72241 agaaacaatc aaaattaatg cgattttgct ttctcaatta cgtttatttt tacagacaaa
    72301 atttcttgta aagattggtt atcagcaggc aaatattgct gaaacattga aaatccatcc
    72361 atatcgtgta aaacttgcca tgcaggaagt aaaaaaattc gatgaacatt tgctggtaca
    72421 gttgtttgat caattagttg agatggatta tcaaatcaaa acgggacaaa tcgaaaaaga
    72481 attaagtttt caactattcg ttttgcgcac agggcagttg ttaagaaatc gataagaaga
    72541 aagacgaggg caaagcatgc gggaaggtcg tttgtttttg tccttttttt gacaaataaa
    72601 aaaatcggcc gaagccgatt cttttattta gcgatttttt tgcttaaacg agatttgtcg
    72661 cggttagctt tgtttttgtg gattagacct tttgattcag ccatatcaat agctttaaca
    72721 gcttctttat ataacgcatc tacgttgtca gcacctgaag ctacagcatc ttcaaatttt
    72781 ttgattgcag tacgcatagc gcttgtttga gatgaatttt tcacattagc gttttcgctt
    72841 gtacgaacac gtttgattgc agattcaatg tttggcatta gtttcacctc cgataactta
    72901 agttcttacg cgtgttaccg cataattcaa cattcattat tatacctaaa ggcagcgtgc
    72961 tttgcaatat gaacatgaca agtttttttc cttaacagtc ttttattagg attttttttc
    73021 agtaaaaacg gatagtacaa gctgaaaaaa atcaaaaaga cgctattgtg ggaggcaata
    73081 gcgtcaaacc aaactagatt tttatttatc tatttaaaca aagtttgaat gggaatgttt
    73141 ggtactaagt tattatataa caaagagaac cgtttgcaaa gttttttttg aaaagggata
    73201 cgattccctg ttgttctttg tttttctatt aagaaactgc agttatttta taaccagtat
    73261 cctttgatca gtaaaggcta ttctggtgta ccgattattt taatgtattc atcgatattt
    73321 tttatcaaca ttttttttat gaccaactgg ttccgacggt tccatttgcc acttacttcc
    73381 agcacatatt tatttagggg caaacgtaag atatattttg ccaaatagcg atctttaagc
    73441 aggccattga tcacacggtc ctcaagctgc aagttgatcc cagtcagcat cattggctgt
    73501 tcttgtaaaa cgtacgtatc aattaaaaga ccttcaaaag tttccacaag cgtcttcctt
    73561 tcttttcaaa gtaacctgaa aacaggcact aattcttcca ttttgatatt cgttgaagtg
    73621 gatgcgatca ttctttcttt tgtccactgt aatctagtat aacaaaaaag agcagaagag
    73681 ccaaaaagaa aaaagagcat cgaattctat aggaagtctc attggcacgg cctaaattat
    73741 tacaaaacat tgattaaaaa aagcccctgc atcgcaggag catcccctat atcgttttaa
    73801 taggtcaatc aaaaagcagt atcaaacaca ttttgtatca aatcaggaaa taatagataa
    73861 gctaagccca gaatcaaaag taccgctaga agaaaccagc cgattgttcc tatgaaatac
    73921 tttaattttt cgaacattgt atcacctcgt tgtcagtata tcacggatca gtaaattggg
    73981 ggtgttaaga atctcctaaa atagacaaaa tttgttctat tttcctaaag caaatacttg
    74041 taagatacag taagtgatac cagaagcaat gaccggtccg gcggcgattc ctcttaagaa
    74101 gacaacacct aaaatcgtgc cgaaaacaag tgcaacagtg atttgtggat cagaagcaat
    74161 caatcctaca cccttggaag ataagacagc cactagccca ccgcaaaaaa cagctaccca
    74221 gccaataggg gatttaaagg cttctaatag atcacgtaga ccgatttctc ctgttgcgat
    74281 agggattaga atagccgctg tgatgatcgt caccccaata ttgattcctt tgccttgaag
    74341 ccaagggaaa aaggaacggg aggctggtat gagcttcata atcaaaacaa aagctgccgc
    74401 tatcatcaga ctttgatttt tagctaaaat tgctacaagt aaaataattc ctaaaaaaag
    74461 ccaactttcc atgaaatata ttcctcactt tcttcgaaac aatcataaca tgtttttaga
    74521 aagttacaaa agtaggaatt catccttcaa gacctattca taagctgttt ttttcataaa
    74581 ataaacaaaa tcataaaaaa acactttgct tatttgacag aagacagccg cgctttgtat
    74641 agtggacaag acttacattt ttttgaagaa tcagaaagat caggtaaagg tcttagtaaa
    74701 cgcaagccat tcagaataac caatattgtg cttccttcgt gtcctacaac tccaagaggt
    74761 agatttaaaa attgcaggaa gttagaagca atcaacaaga gaataacaag aatcgaaaaa
    74821 ataatatttt gtttgatgat ccgccgcatt tttaaagata gccgatgact gtagacaaat
    74881 ttatttaagt cgcttttcat taagacgatg tctgcgatat ccatagcggc atctgtccct
    74941 tgccccatag cgacacctaa agaagcggct gctaaagcag gcgcatcatt gactccatca
    75001 ccaaccatcg catttacttg gtaaagttca ttctcttttt tgactagttg tgttttttct
    75061 tccggagtac agcttgcata gtaatgttca atccctactt gttcagcaat ggcctttgct
    75121 gtgccagaat ggtcgccggt tatcatactt gtatggatgt tttgggattt aaagtaggaa
    75181 attacttgtt gggtatttgc ttttggaata tctagcagac ctaaaacagc aattaactgc
    75241 tgatctttag aaagataaat cacggttttg ccttgatttt ccaaacgttc gatcatttcc
    75301 gcaatctctt tgctgattat catcgtctca ggatcatatg cgtgcttgcc aactttccat
    75361 tgcgcaccta aataggtagt ttgtaatcca aaaccagtaa tttcttctat tggtaagtat
    75421 tggatttctt caggtattgt gcaatcgaaa tattgcaaaa tcgcatgagc aagtggatgc
    75481 gtcgtttttt gttccatagc aacaagaagt tgttgtgcca aatccttttc atcaaagaaa
    75541 aagctgtcag ttacaactgg ttttccttta gtgagcgttc ctgttttatc aaaggcaatc
    75601 gcttttaatt cagaaagctt ttctaaatgg ataccgcctt tgattaaaat cccatttttt
    75661 gcagaatttg aaagagcagc tagagaagct ggtgtagcag atgcgacaag cgcacaagga
    75721 gaagccacaa ctaataatac cattcctcga taaaagcttt catcccaact ccaacctagg
    75781 aaaaagtggg ggagaaggat cattagagga acagcaagca aaatcaattt tacataatta
    75841 ttttcgattc gttcgataaa tgaagctgtt tgagttggcg tattctgcgc ttcttctact
    75901 aattggataa tcttagcaaa gacagtttcg gaactcgttt ttgttactcg aatcgtgatg
    75961 ggatttcctt gattcagcgt tcctgcatac atctcatcgc ctaaatattt ttctacaggc
    76021 acagattcac cgcttaatgc agactcatcg atcgttgcct gtgtgctttc taaaaagcca
    76081 tctatcggaa cagctgctcc tttagcgaca aataccaagt tatccacctt tagttgagaa
    76141 acatctactt cttgcatttg tccattttct tttaataatt gggctttttg tggttgaaga
    76201 ttcatcaaag cagtaatttc tttttgactt ttattagttg tgtattcctc taatgcaccg
    76261 cttaaacaaa agatgaatgt caacattgct ccttcaaagt aattaccgat caaacaggca
    76321 ccaatagcag ctaaagccat caataaatcc acattcagtg tccgatcatt ccacaattct
    76381 ttcaagcctt ccgatgtttg tttatatcca ccgatgataa tggcactgat ataaaaaagt
    76441 ggggtgatgg taagagagaa tcggtcgaag ataaaaccga agatcataaa taaaaggcag
    76501 ccgattgttg ctgcaaaagc ttttttctga ttagtcatcg ttattagacc tccttgtcaa
    76561 aacaaggata gcataataaa aatgtaattg ataataataa cagctaaatg agaacgataa
    76621 tggttatcat ttggtgatta agcttgatgt tgtttttatt atttataatg attattatta
    76681 aagaaaataa aaaaccagaa catttctcaa ataagagaag tgttctggtt ttttctacat
    76741 tgcaataaac caataaccaa tcaaaatgat accaaggata atacgatacc agccaaaagc
    76801 ggtaaagtcg tttttcttca aatagcttag taagaatttg atagctaaga cggaaaccac
    76861 aaaagatacg aatgttccta caagaagaac aacagtttct tccattttga atgaattccc
    76921 ttcagctaaa tatttgacga tcttcaagcc gcttgcgcca aacatgacag gaatccctaa
    76981 gaaaaatgaa aactctgtag cgacaaaacg cgaagcacca atcaagatag atcctaggat
    77041 cgttgcgcca gaacgggatg ttccgggaac aagtgccaag acttggaata acccaacaag
    77101 aagagctgct tggtacgtaa agtcattcag agaagtccaa cgaggtgttt tgtttttgtt
    77161 gcgtttttcg acaataataa aggcaatacc gtaaacgatc aaaacaatgg caactggtaa
    77221 gaacttgtgg aaatttgctt ctaaccaatc atccaaaggc aaaccaatga tgatggctgg
    77281 tatgcaagca acgatcactt taaaccaaag tgtccacgta tctttttttt ctaccgttga
    77341 tttacttgga gaaaatgggt ttaacttgtg aaaataaaga acgacgacag ccaagatcgc
    77401 ccctaattgg ataacgacat tgaacatcga cataaattgt gaactggcat ccagtttgat
    77461 gaattcatct gctaggatca aatgaccagt actactgatg ggcacccatt ccgttattcc
    77521 ttcaataata ccgagaatca ctgctttgat aatatttgca aaaaacataa attccttcct
    77581 tcccaattaa gatacatctt atagtatacc gttatttttt gagaaaccca atctgttttt
    77641 taatattaag aaaaacttga gaaataaagc agataagtac acgaagagaa aaaagaagac
    77701 aaagccctcg ttcagacttt gccttttatg attctctggt aaaaattaaa atatccccat
    77761 tatagaaacg agtcgcgact atgtgttttc ccgttatcga tataagacgt atcattgatg
    77821 ccgtggatag aaaatcgacc gtttgcataa gtgacctttg ttacgctgcc atttaaaagc
    77881 ccagcacgaa caggctgttt aggatcgatc agattaagca aaaaggcgat cgtcaaacca
    77941 tgagatacga ctaaaacatt tccaccacca tttttttcgc agtgatgggc gatatcttca
    78001 aatcctgtcc atacacggtc tcgcaatgtt tcataagttt ccgcccaccc agcggtatct
    78061 aagttgtata cagcattagc aatttgttca aaagaaactt ctgtggtaaa catttcatca
    78121 tatgttttaa aattcaatac acgagggatc acaccccaca tttccatgtc atatccacct
    78181 tcaagagacc cgaaacacca ttctctaatc cttttttcaa taaaataagg aatttctttt
    78241 cccttagaat gttctcctag aataatacgg gcagtttcga ttgcacgacc actgtcacta
    78301 gaataagcaa atgaaaagtc gacatttttt aacccgcgac ctaaataatg aatgccttct
    78361 tgtccttgct ttgtgagggg tgtatcacac cagccttgta ctcgttcaat tgtattgaac
    78421 atcgtttttc cgtgtcgtac gatataaagt gtagtttctg tcattttatt ctcctcctaa
    78481 gtcgttttaa cgattgaaaa aaggatttgt ccttttttcc tgttcaatcg tcgttgcatc
    78541 gccatgtcct ggatagactg caaattcatc aggtaataca aacagctggg tccgaatact
    78601 atgaagtaat tgttctaaat tccctgtata cagatcggtt ctaccgatac ttcctctaaa
    78661 cagggcgtcg ccagaaacga caaaatcatc aaaaataaag ctgacgcttc ctatagaatg
    78721 ccctggggta gggacgacgc gaaaagacat gtttcctaaa gtataagttt tcatttcaaa
    78781 ttcatattct gcaggcgaga caataacatc agcaatatca tcatgtctac cgagtccaga
    78841 aagattcaaa atcggatcac ctagccattt ttgctctagt gggctgacat aaactgggat
    78901 ttgataatac gcgcgtaaag gttccactgc accgatatga tcgtagtgag tatgggtaag
    78961 caaaatcgct accggctgtt ggtttgtttt tttgatttct tgtttgattc gttccgcatc
    79021 ttctccaggg tcaatgatca aaagtgcttc ttcgttgtag accaaataac agttttcttc
    79081 aatcattcct gtttttaatc tttcgatatg catgtgcatt cctccttgat agccaaaact
    79141 tctttcatcc attagtataa cgcattcatt gctaggaaac aaaaacaggt acttatttct
    79201 ctttacttat ctgaattatc agactatatg aaaagtattt ggatattcta aagagaagga
    79261 aagtaagttt tcatagcatt ttaatatgtc cttgttacat tagattcatc caaaaatcca
    79321 aattctatat cctatatccc tgcctaatca gcagggtgtt tttttatgtt tggaaagaga
    79381 gctctttttg ctaaactagg ttttttcagg taatcttaga gagaaagagg tggtggaaat
    79441 gatcaaacag tcaaaaatat ctgtgcggca cttagtagaa tttattttgc gacgtggaag
    79501 tatcgacaat cgtaaaaaaa gtaaccatac tgcattagaa ggagcgagaa tccaccgcaa
    79561 gctccaaaaa gatgcgggag aaaactatga aaaagaagtc tttttaaaaa caacagttca
    79621 attagatgaa tattacctga tcgttgaagg ccgtgcagac ggtattttca aaagagacgg
    79681 tatttattat atagatgaaa tcaaaacctc cgaaccacga tttgaagatt tagaaccaga
    79741 acaagtggaa cttttctttc atcaagcaag ggtgtatgcc tatatctata gtcaagaaca
    79801 tgatttacaa gaaataaatc tgcaattgac ttacttccag acggcagaag aagtgatcac
    79861 gagaaaggtt gaacatcaga caagagagca gttagaaact ttttttaaaa agctgactga
    79921 agattataaa gaatggcttg tttttcaaga aaactggcgc actgtacgca atgcctcttt
    79981 gatggctttg aaattccccc atgatgagta taggaaaggt cagcgtgaac tagcggtagc
    80041 tgcttataaa acgatccgta cgaaacagaa attgtttgta gaagcaccta ccggaacagg
    80101 aaaaacaatc tctacgttat tccccgcttt gaaagctgta ggggaagaag agggagaaaa
    80161 gatcttttat ctaacggcta aaacaataac tagacaagta gctgaagatg ctatgacagc
    80221 attaaaagat acaggagctg aagtaaaaag tgtcactttg acggcgaaag acaagatctg
    80281 ctttttagat gagacgacct gtaatccaga tcagtgccca tatgccaatg gttattacaa
    80341 tcggattaat gaaggtttat gggatctttt gaatcatgag aatcagatca ctcgtgaagt
    80401 catcgaaact tatgcaagaa agcatacact ttgtcctttc gaactatcat tagatgtcag
    80461 tatctggtgt gacgtaatca ttggggatta caattattta tttgatccaa ctgtttattt
    80521 aagacgtttt tttgaagatg aaaaaaacga ggactatctg tttttgattg acgaagcaca
    80581 taatttggtg aatcgttccc gagagatgta ttcggcagaa ctatcttatg aaaaaacgaa
    80641 acgaagtaag gaagctatac caaaggaatt caaaaaactt catcgccgtt tcaacaaact
    80701 attaaaagaa tttgattcga tccgagaaat agcaaaagaa gatcattggg attatcatca
    80761 tcaaaaagca ccggctgaat ctttagtaaa ggcaggttat caattaagcg aaaaaattaa
    80821 agaatggctg gcagaatttc ctgagcaccc atcacaagaa caattgcttc cttattattt
    80881 tgatttgctt cattttttga aggtcagtga attttatgat gatcactacg aaacaacagt
    80941 cgaaaaaacg tatcgcgatc tgatagtaaa agagttttgt attgatccaa gcttgtttct
    81001 tgagcagtcg ttggataaag gaaaaagcag tattcttttt tctgctagtt tttcaccact
    81061 ctcttattat caggaaacac tggggggaca aaaaagtctg gcttacaaac tgccgagtcc
    81121 tttcccagaa ggaaaccagc aagttttcat cgcaaattac ctagagacga cttatcgaaa
    81181 aagggaacac agtctggcaa aattagtaga gacgattcat gcttttgctg atggaaaggt
    81241 cgggaattat ttcgttttct ttccttctta tcaatattta gatcttgcgg tggaagcatt
    81301 cagacagcaa tatcccgaca gcaatgtgct aatccaagaa acggacatga atgaggaaga
    81361 acgcgaacga tttttaacaa aatttcaaac aaatcccgct gaaacattga ttggattttg
    81421 cgtacttggc gggatttttt cagaaggaat cgatttgaga ggggaccgat tgatcggcag
    81481 tatgatcgta ggtgtaggtt tgccgcagat gaatcatgag caggaactga tcaaatcata
    81541 ttatgatgag aaggaacacc ttggatttgc ttacgcttat cagcttcctg gaatgaacaa
    81601 agtcttgcaa gctggtggtc gagtgattcg tggcatggcg gatcaaggaa tcgttgtatt
    81661 ggcagatcaa cgattttcta gtttttctta tcgacgttta ttcccacaac attggcaaac
    81721 agcaagagaa gtacgaagtg ttggggaatt ggaagaagga atacagcgtt tttggttatc
    81781 aaaagaagca gtaaatcaaa aaaacgagga atgacagacg tcagcctcgt tttttgatta
    81841 acgatagtta gtgaattgca actcgattgg taagtcaagt ttacgtaata aagcaatcac
    81901 agcttgtaga tcatcacggt tcttacctgt cactctaatc tgatcttctt ggatttgtgc
    81961 ttttactttc agtttttcat ttttgatagc tgtagtgatt ttcttcgcgt tttcacgatc
    82021 gattccgttg accaaatcgg cagtttgtcg agctttgcca cctagagcgt gttctgattc
    82081 ggaaaaatgg atatttttga ttggcacatt tcttttgatc agcttaccaa ataatacatc
    82141 tttgatctgt tcgattttga aatcatcatc gctcaataca actagattgc tgttctctaa
    82201 tttgatttct actgtagaat ccttgaagtc aaagcgattg gacaattctt ttgttgtttg
    82261 ctgaatcgca ttttttactt cttctgtatt gacttctgat acaatgtcga agctagcatc
    82321 ttttgccata ggaaccctcc tgatatacat ataaatattt accatacatc tatcttatca
    82381 taggattagg gcagattctt acctgtttgc taaaattctt ctcatttgag ttcgaagtat
    82441 tttattttaa tagataaact gttattctta catttggaat accaaagtag gggagaggtg
    82501 cttgtgagta aaattatgac tgcgtatcat aaaaatgaaa gattaaagaa aatagtggtt
    82561 attttgataa ccggattgac cgctgcggtc gctttaaatt attttttgat tccagccaat
    82621 gtcttttctg cagggatgaa tgggatcgct caaatcattt cctcgctttt atatgaatgg
    82681 tttcatatca agatagacac aggaacattt atttttcttt tgaatatccc tgtgtttgta
    82741 ttagggtttc tcaaagtagg aaaacgagca acgatcctta gttttgtgaa tgttgtatgt
    82801 gtatcggtga tgacgatgct gcttccagtc ggacagatca ctgataatat tttgatgaat
    82861 gccctagtag gcggtgtttt attaggtctt ggcgtaggat tatctttaaa aatgggcttt
    82921 acaactggtg ggatggatat catctctctt gtactttcac aaacaactgg aaaaacagtc
    82981 ggaaactaca tgctgattct aaatggtatc attgtagtca tcgcaggctt cttctttaac
    83041 tgggaaagtg ccttgtatac gattatttcc atttatgcaa tgactcaagt aattgatgcc
    83101 atccacacga gtcatcaaaa agtaacagca atgatcgtta ccgtcaagcc agaagaggta
    83161 acagaagaac tagcaaaacg gatggtacgt ggaatgacat tactgccgtc tgtcggtggc
    83221 tattcaaaaa aacaagggaa catgatcatg atggtcatca cccgctacga aatgtatgat
    83281 cttgatcaga tcgttcatga aatcgacgac gatgcattta tcaatatttt accaactcat
    83341 tcagtatttg gccggtttgc aaatgaaaac gaacaaaaaa tgtatcgaac aactggcgta
    83401 ttgccagaaa taaaaaatcg ttcacaaaaa aaatgaggaa tcaggtttat tttagaataa
    83461 atttaatcta ttacatctaa taagaacatt tttataaatt taaacgagaa tcttacttct
    83521 aaattctcat ttacaagcag ctaaaaaaag agtatgataa ataaaaatcg tgttaaggag
    83581 tgtcgtacga tgagcgaagc aaaccaagaa cggtctggac aagaaataga actaatcaaa
    83641 gaacgtattc ttgctgcctt ggaaatggtg attgatcctg aattaggaat cgacatcgtc
    83701 aatttaggct tgatttatga tatagaattc aatcctgaaa atggagaaac agtcattaag
    83761 atgactctaa caactatggg ctgtccatta gcagatattt taacagaatc tatccatgac
    83821 gcattaaaag aagtgccaga agtaacgaaa gcagaagtca aactagtctg gtatccagca
    83881 tggacgacag ataagatgag ccgttatgca cggattgcgt tggggatacg atagaaatct
    83941 tggctgacta gctatgagaa gcaaatagga aaaacaaaaa agccttttat cctttctaga
    84001 agaaaagaga taaaaggttt ctttgtttat aaaattttgt ctgctatatt ataagttaat
    84061 taaataaatg tgttctattg ataaaggaca ttcaaatccc tttccttttg gaatccttct
    84121 tttttacatc agtttgattt tcgtatagta ttctttctca tcttcacgat aaatcgcagc
    84181 cccatttttt tgttgtgctt taagactgcc aagatttttt ttatttacag acaaaagtgc
    84241 ctcatcaatg ccgatttttt ttgcctcttg tagtactaat gctaatcctt gtgtggcata
    84301 tcctttttta cgataattag gggagatgcc gtaaccaata tggccagcgc cgtttcttaa
    84361 tgtttcgttc agtttatggc gcaaattaaa aattcctaca tactcatgtt catcactttc
    84421 taaaataaag acggttgcgg gaacgtaact ctcaggaaga tcgattccta aagacgtttt
    84481 ttcgcatttt tttacataat ctaaaaattc agcaaatgta tagccataag cattgttgat
    84541 aaatccactc tcatttggtc caaagctagt ttgtagctga taagctttct ttaaatctgc
    84601 ttcccatagt ttgatcagtt tcatcgtatt cacctcttta agtaacctta ttcatttgtt
    84661 ttctactata gcactattgt tgtaaatagc catgcctatt tttatttatt gtgtcatatc
    84721 gtattaagaa tcatcgaaca atacaaatat gaattacaat aaaaaaatta tttgaagttc
    84781 gttcattcgt tacttatgat ctctagaaga aagaaaacgt gaattacttc agcgtctaga
    84841 attccagaag gatagtaatc aacagaagaa ataatcaata tccaaatgaa agaagatagc
    84901 tgaatcgaga aaaagaggaa aaaagaaatg aagaaaaaaa taaaatagtt actaatccca
    84961 gagtcgttcg tttaacattg aaatcgatca tatggataaa acagattttt tcaccaaccc
    85021 tcaatagatg atggagttgc tcggatgaat tatttgtgta gatggcataa gggagggcgt
    85081 acagaaatga aaaagaacaa aaatatgttc ttgacaaaaa acacatgtaa tcctaaacta
    85141 aaagatgtga tgcggctatg gcggaattgg cagacgcgct agcttcaggc gctagtgagg
    85201 gtgacctcgt ggaagttcga gtcttcttag ccgcataatt tgttttttta taaagagaag
    85261 gtacacctgg agcgatgaga aagaaaataa catattatct aaaagaatat aggaaaaatt
    85321 ttaaacaacg gaaccagatt caaataaatc aaaaaaaatt tgtgtgaagg tgggacagtt
    85381 taaaacctaa tagattgatt caaatagtag atttatagat tctgatacaa gaaatactgg
    85441 caaacgatag ttaaggaata aagactaaac ttaaactcaa aaagaggtca tgcgaaagaa
    85501 taaatcgcat gacctcttac tatattttga atgtgtttaa acgttcaaat aatgaatctt
    85561 agtaccaacc gtttgcttcc cagaatgctt tcgccgcttc ccaagaacca taacgtgaag
    85621 taacatattg ttctgctact ctttcttggt ttgcagcaga gtagtcacca tttaagtaag
    85681 aagaatctaa ttggtaacgg ccgatgtaac gtccgttcgt tgctgtgtaa gaaccgcttg
    85741 attctttttg tgcgatccat tcttttgcag agcttgtact tgctggagta gcagcagttt
    85801 ctgttacagc aggagcaggt tgtgtttcag caacaggcgc tgcttgtgtt tccgtttgaa
    85861 ccgtttcttg tacaacaggt tgttcagctt gaacaggttc agcttggact ggtgcttctt
    85921 gaacggctgc ttgaggttca gcagctgctt gtgcagagcc ttctgttggg attgttaatt
    85981 gttgtcctga gtagatcagg ttaatatcag aaattgaatt tgattctgca atggcattga
    86041 tcaaggagtt atcaccaacg tatttttgag aaatcgttga tagagtatca cctgattgaa
    86101 cggtataagc ttcgtccgca tgagcagtcg ttcccatgaa gaatgcagcg ccggcagcca
    86161 aagttgttcc aaaaagtaaa gttttaagtg atgtcatgaa aaatctcctt tattcgttaa
    86221 aaagttttat ttgttgtgtt caacgaggaa tactttaaca cgtgaaaata tttcataggt
    86281 aaaagaagca tgacaattta tgacaaatcc acgttttttg taacagaatg atgttcgctc
    86341 gatgtgaaaa atgatgagga atttcacata atgcagaaat aatgggatta gaacaggtgt
    86401 tctgatgaga aaagaaatgt ataaataact tgaaagaaat tgcttttgtt catcatttta
    86461 tttacatatt gcgtatattt tttgtatttt tgcttgagat gttacaataa aagaaaaagg
    86521 aggcggttcc aatgagtaaa agataccaga acatcatggt agcagttgac ggatcaagac
    86581 aatcgatcaa agcgttcgct gaagcccttg acttagcaaa ggacaatgaa gcccacttat
    86641 ttatcgtgtc aatcatcaac aaagttgagc tgacccatag tgcctatgcc ttttcaaaaa
    86701 tctatgcaga tgaaaaacaa agaacagaag tagccatgct gaaaaaaatc aatgatgcca
    86761 aagagtacgg cattgctgag atccacgcaa tagttgaaac tggagatcca agaaatttga
    86821 ttgccaatgt catccctgga caagaaaata ttgatttgat cgttatggga gcgacaggaa
    86881 aaggtgctat acaacaagca ttagttggat cgaccgcttc ttatgtcgta tcacatgccc
    86941 cttgcagtgt gttggtcgtg aagtaatgag ataagggagg aatagaaaat ggttcgtcct
    87001 caagaagtcc gtgcgccaaa agaaaaaata gaaattttag caattattga agacggcaca
    87061 caaacaaaga agggatactc gatcgcttta gtaaagtgga aaggaaaaaa aggtgttgct
    87121 ctgagatggg atggagataa ccaacaagat aaaggattcc ctgtcacagc taacggttat
    87181 catccagcgt ggtttgttct gcctgataaa tttatggaat tatacagcta tgattatgca
    87241 agagccgcag catcaatcaa agcattagat aaattaacag aagagcagaa tgaaatggag
    87301 gaaaaataaa aaagacgaac caatcagcct ttagaaaact gattagttcg aggagtaaaa
    87361 atgaaaaaag gttatttggg atgaaactag aataatgcgt ataacttaaa taaaacttaa
    87421 agcaataaaa tggcaagagg gtgaggcaaa tggaagcagg aaaagtatta caggaagtaa
    87481 aagcactatg tgcagataaa aaatatgaag aagcgaaaag cctgatcgaa aagaacaaag
    87541 aaaatttgga agaaaagtac ccgatcgcac aagaatttat agaattaaaa caaggaacga
    87601 tccttcaccg attcaaacat ttttttggta taacagaata gaaaaaacga ttaaagatcg
    87661 gcagaaattt gctgcatctt taatcgtttt ctttttaaac atgcgaggga ttcaattctg
    87721 attcttatat aaaaaataga tccaaataat aagaaaaatt actgaaagcg tcaattcgat
    87781 gatgtgtgtt attaatacag acgttgtttc ccaatgccta aaagaaaaaa tttgataagt
    87841 aaaatataca gcaggtaaag aggccagtaa aactgaaaac ttcttttttg tccattttat
    87901 gtaatagaaa agaatgctta tcataataaa aaaaggaata taaaaaacaa attgaccgat
    87961 cgcgatcata ctattgcctc cgataaataa agtccatgat acaaaataac actttgtgcg
    88021 aaatggcgca agcagttttg tggatttatc cggtaaaatc tgtatcgatt ttgaaattag
    88081 aggagaaact tgctataatc aaagtgaaag aaggagtggg attttcatgg atcatgtagt
    88141 gttagaaatc gatttgcatt tgatcaataa tattcgggtg atttactatg ttgtaagtaa
    88201 cagtgtcgaa caacgtgtac tgacgaataa aataaatggt attttagcaa agaaagacgt
    88261 tcaccgattc aataatggtg aaggaagtta ttatagtatc ccagtagaaa aaattattta
    88321 tacgacagtc aaagtcagag aagatctaga taccaaaaaa gcatatgaac ctatttttac
    88381 aacttattga ttgacagcag atggaggaaa aaaatgaatc catatgaaca acttattcaa
    88441 gatttgatcg atggaaaaat cgaaaagatt gatgtaaaaa gagaagaatt aatggctttt
    88501 cgagaagcgt ggctgaagtt ggagaatcgt aaatatgtgg tgggaaaagc ctcactgaac
    88561 ggcaatgtga cttatcatta cgatccgaca cgtttatttt agtatgaagt attcagaaaa
    88621 gaaccaaagg aggacgatgc agcagcattg tcctcctttg attttacaaa agtgaaagtt
    88681 ttacttattt gaatagattt ttaaatttgt ttttgacact gtcgatattt acatctttta
    88741 aaagattttg ggctttctct ttataaggtc ctaattgttc tttatgttct tcgataaatc
    88801 gttttgcgcc atcgaaattg ccgttcttaa tcatttcctt gactttttga aataattctt
    88861 cttgattcat tttgaacaca tcctttgcta tcaacatgat tttttacatg gacaaaacga
    88921 gaaaaactga tttatccaca cgtcaataat atcaaataac gatcattttt actaaaaaaa
    88981 cactcgattc tcgcttctaa agtaggagaa aaatctccaa cttgggacgg atggaatttc
    89041 tttaactgac ccatatactg aatatataac aaggaggtag aaagatgaaa gtgattaaat
    89101 atttgattgg actggcggcg attagtggta ttttgctatt tggactgaaa tattatactg
    89161 aaggaagtta tggagaaatc cctggtatac ttgatcagct aaatccatta gttgaaaaag
    89221 gagaggtcta tgtaaagaca caaaaaccag aggaagtaaa tgaatatggt acagcaaggt
    89281 atgtgcagaa agctgctgat gccaatggga aagaacgaac ggttgaattt aatggtcttt
    89341 ctgtgttaaa agaaaatcat tatttgaaaa ttagcaataa aggagcacac atagaaacgt
    89401 atgaggaagt tcctagagaa aaagttccgg agaaagcatt agcaattatt gggtaaatca
    89461 gtttttgtat taagaatacg cccgatttta ttattcataa tttaattatg taaactaaat
    89521 tctagtagta aaaataatac aataatcccc ctgcaaaaag attgttcttt tacagggggt
    89581 tcattttttc agcaagcaca tcaaattggg atggcagggt tcgaacctac aattgcttga
    89641 ttcagagtca agtgccttac cagtttggct acatcccatt tattcaacaa aataatcata
    89701 gcactttcct aaaaaaacgc aagttatttt tcttgatcgg atagttgttg ctttactcgt
    89761 aaaaggcggc gtactagttt cttttctaat ccagcaggaa gggcaatcag ttctgctact
    89821 gacaagacgg tgtccaataa ctgatattct ttgacaggtt cattcataat atgatagatg
    89881 tttgctaaac gttcaatata ttcaaagcga gtatactctg ttcgagcaat tagaaatttc
    89941 aataaatcgg tggctttctc gtactcttga tctgcgtaat aaacaagaga ttgacgatac
    90001 aatttgattt ccagttcatt gagggtagca ggtctgcgac gctcgttcca ctcattaata
    90061 gagactttac cttgaacatt tcccttgcag tcacggacaa aaataatcgg aatttcattt
    90121 ggatccattt ttttatgtgt gaatttttcc attatctacg ctcccttcaa aggtttggta
    90181 tcttgagtat aagggatttt tgtttgaatt actagctttt ctccaaagtt agcatctgtc
    90241 cacccattgc agtgaaaatc gccgaaaaat cgttgatcgg tactgctcga ttttttacac
    90301 catagggatc gttgacataa atattttctt tgtcatatcc agtgactaca caagcatgaa
    90361 caagaggagt gactcttact tctccattat ttgtggtcca agtcataaaa tcagtttcat
    90421 ctgggacttc aaaattgata gtcacagaag tccagacagg atttccttta gatagtgctt
    90481 ttttgatatc atcgagttga gcatcggttt ttggaaaagt gtgataatcc gtttggacga
    90541 tttgctgagc aagggaggca actgggggaa catagacgac catagcccag tctccgccac
    90601 tgatatcacc aacaaatcct tcattaggat cgccatgagt cccatctgca ttgaaaacag
    90661 ggacgtaatc caattgctca gctaactggt ttttagttgt ttcataacca taaaaagata
    90721 aaagcataga aagcgaagtg acttcacagc cattttctaa agaaggagaa tcaaactggc
    90781 tctctaatgg aacatctagt aaaacttctg ctttctcttt tgtctttttc gttttttgtg
    90841 ttgaactttt ttgtgcagtg ttcattgtat gttctggaga atggatatgt aggtaataac
    90901 ttgtaccgct taataaaaga gcagctgtgc cccctagaaa caatagtttt ttgaacgttt
    90961 ttttcttcat ttgaaatctc ccttttcagc tgtttatctt tcctattata aatgtatttt
    91021 tattggaaat ggaagtatta tattttaata tgtaggaaat aattagtttt taaggaatat
    91081 gttttaattt tttgaaaaaa attcttctaa atacaacagc tgttttaatt gtgaaaacga
    91141 aaacagtacg ctataatgcc tgtaaggttg atttttaact gtaaataaaa atcaatgagt
    91201 taaatctcca aagaaatagc agtggtaatg tggagaaaag ttccagcagt ttaggaggat
    91261 tttgatgacg gaagaaatga ttaatttagg agaacaatat gcatgcaaac caattggttt
    91321 tacaaaaacg gtcattggtg aagttgtatc aaaaatgaca aactgcgccg tggtcaaagt
    91381 tgcccaatgt gctgcagagg accaagaatt attagatgaa aaagcaagca tggttgttgc
    91441 aaaatatgat acatttgaat aaagaaaaca attggacgtg cggcgtgctg caagtccaat
    91501 ttctttgaga aggtaaatca gtattctttt cctattttct ggagaagaaa aagcgaggcg
    91561 agttgtcatg gtaacattct ttacggttct attgttttta ttcgttgttg tgatgttttt
    91621 atttctttgg ctggttcgaa aagaaattat ttatcggact gtgcgaaatc gatgggtcta
    91681 cttggtgata cccttcttag tgtcactagt catttggtat acactcatca gtcatcctac
    91741 agcagatgaa ttggcaaaag ggatcttgtc agcaatgatt tttattagtt ttttgttgga
    91801 cagtagagga atcacagaag aaggacttgt tttgaatagc tttgacaaaa aaggtgttcc
    91861 tttttctgag atcaataaaa ttgtattata tcagccaaaa ggttctaaaa tcgtaaaaat
    91921 gaattttttc cgaaacggat ggcgaggacc gatgctgaaa ttttctgcat cattagaaga
    91981 attagttcca tttttgtccc aacgcttaaa cgatgaggca gagattgata ttatgattga
    92041 tccagaataa aaacagaggt tgcgacaaga tgtttgtcac aacctctgtt ttttatttca
    92101 aataaaatta tccaaatacg cggaagcgat cggcatcgtt catgtattct ttttccccag
    92161 ccggtgtttc tggtgaaccg aatactaatt gcgaacgtag tttccagttt gaagggatat
    92221 tccattcttt tgcaactgct tcgtcaataa ctgggttgta atgttgcaag tttgcgccca
    92281 atcctttatc aactaatgct acccaagtat tagctgttgc gattccgttt gattgttctg
    92341 accaatctgg gaagttgtct gcatataatt caaattgttc ttgtagacct tttaccacgt
    92401 cagtatcttt gaagaataat actgtaccat aaccattttt gaaaccagct aatttgtttt
    92461 gtgtatttgg gaaagcttct gctggagtca atgggcgaag tgcttcttca gtgatttccc
    92521 aaagtttttc atgtgcatct ccgaaaagga taactgcgcg tgttgattga gcattgaaag
    92581 cagttgggct ttctttaatt gcttctttga tcaaagttgt taattcttca ttagaaagtg
    92641 aaacattacg tcctagatga tagattgaac ggcggttttt caaagtgtca gtaaaagttg
    92701 tcataataaa atttctcctt tgatttgcgt tttgcatttt tttaattgat tacgaaatga
    92761 agtatagcac cttacaaaaa gtaagtaaac agatatgctc acaaaaaata agcgaagttc
    92821 aaaaaacaat tttaataaga aaaatcgtta tgtaaggatt ttcttagtta tcgctttcat
    92881 tgttgtgttt taggaatttt tgcttatttg aaaaaaacag ctgatatata attattaaat
    92941 ctctatcttc ttttttttat gatattgcca ttaaaaatta cttgctttta tagaaaatta
    93001 gtttatattt cttaaataag ttttttagtt aaatttttcg gtaaagatgt ataatatttt
    93061 ctgaaaattt aaagaattgg ggtatagatt atggaaaaac agcaagacaa gggcttcttc
    93121 gggcagccga agggattgtc aactttgttc ttcactgaga tgtgggaacg atttagttat
    93181 tacggtatgc gtgcattact tatctattat atgtacgata cagttgccaa cgggggactt
    93241 ggattaccac gagcaacagc attagctatc atgtcgatct acggatcttt gatctacatg
    93301 tctagtatcg tcggcggatg ggtatctgac cgagtgttag gagcaaaacg cactgtattc
    93361 ttcggtggag ttttcattat gcttggccac atcgtcttgg ctttaccatt tggtgtaagt
    93421 acattgtttg tttcgatggc attgattatt atcggaaccg cctttttgaa accaaatgtt
    93481 tctggcatgg tcggacatct ttattcaaag actgacttgc gaagagatgc aggattttcg
    93541 attttttaca tgggtgtcaa cttaggggca ttattagcac cactaatcgt tggtacaatc
    93601 ggtcaagaat ataactatca tttagggttc tctttagctg ctattgggat gttctttgga
    93661 ttattacaat acatcatcca aggacgcaag acattagacg gagtgggtac aacaccgccg
    93721 aatcctttga caactgaaga acgtaaagga ttcatccgta acttgatcat cgcacttgtt
    93781 gttatcgctg cagtattcgg cggggcacaa ctaactggtc atctgacaat tgactttttt
    93841 gtcaatacaa tcagtgtatt ggggattatc ttaccgttgt attactttat caaaatgctg
    93901 acttcaaaag atgtaactgc tgaagaaaaa ccaagagtat gggcttatat cccattattc
    93961 cttgcagcaa tcattttctg gtcattacaa gaacaaggtt catctatctt agctttattt
    94021 gctagtgaac gtacacaatc tacgctattt ggtgtaacga tccaagcaag ctggtatcaa
    94081 tcattgaatc caattttcat ctttattctg acaccagtat tcgtaacgat gtggacgaaa
    94141 cttggtgaac gtcaaccatc tacagtagtg aaattctctc ttggactttt atttgcagga
    94201 ttatcgtact tgctattgat gttgccgggt atgctttatg gtacaagtgg aaaagtaagt
    94261 ccattgtggt tgttgggaag tttcttcatc gtggttattg ctgaattgtg tctttcacca
    94321 gttggtttgt ctgtgacaac aaaattagca ccacgagcat ttgaatcaca aacaatcgct
    94381 atttggttct tagctgatgc ttcttcacaa gcaatcaatg cacaaattgc acgcttctac
    94441 acaccgggaa cagaatctgc ttacttcggt attatcggtg cagtagcaat cgtcggtggt
    94501 atcttgctat ttactgtgaa agaaccaatc aaaaaactaa tgggctctat tcattaatca
    94561 atgaacataa aaacaggaat tgcttatttg cagcagttcc tgttttt
//
LOCUS       DAPBBV010000006        92657 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.006, whole genome shotgun sequence.
ACCESSION   DAPBBV010000006 DAPBBV010000000
VERSION     DAPBBV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 92657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.006"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            21..1658
                     /locus_tag="RD486_000564"
     CDS             21..1658
                     /locus_tag="RD486_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662324.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(1803..2543)
                     /gene="truA"
                     /locus_tag="RD486_000565"
     CDS             complement(1803..2543)
                     /gene="truA"
                     /locus_tag="RD486_000565"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDT7662325.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2734..3369)
                     /locus_tag="RD486_000566"
     CDS             complement(2734..3369)
                     /locus_tag="RD486_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HDT7662326.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3516..4757)
                     /gene="sstT"
                     /locus_tag="RD486_000567"
     CDS             complement(3516..4757)
                     /gene="sstT"
                     /locus_tag="RD486_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HDT7662327.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4955..5953
                     /locus_tag="RD486_000568"
     CDS             4955..5953
                     /locus_tag="RD486_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662328.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            5966..7984
                     /locus_tag="RD486_000569"
     CDS             5966..7984
                     /locus_tag="RD486_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HDT7662329.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8044..8760)
                     /locus_tag="RD486_000570"
     CDS             complement(8044..8760)
                     /locus_tag="RD486_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HDT7662330.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(8987..9529)
                     /locus_tag="RD486_000571"
     CDS             complement(8987..9529)
                     /locus_tag="RD486_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDT7662331.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(9534..9761)
                     /locus_tag="RD486_000572"
     CDS             complement(9534..9761)
                     /locus_tag="RD486_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7662332.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(9840..11720)
                     /locus_tag="RD486_000573"
     CDS             complement(9840..11720)
                     /locus_tag="RD486_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDT7662333.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(11909..12523)
                     /locus_tag="RD486_000574"
     CDS             complement(11909..12523)
                     /locus_tag="RD486_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662334.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            12665..13225
                     /locus_tag="RD486_000575"
     CDS             12665..13225
                     /locus_tag="RD486_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7662335.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(13530..13844)
                     /locus_tag="RD486_000576"
                     /pseudo
     CDS             complement(13530..13844)
                     /locus_tag="RD486_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(14098..15733)
                     /locus_tag="RD486_000577"
                     /pseudo
     CDS             complement(14098..15733)
                     /locus_tag="RD486_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16056..16535)
                     /gene="rlmH"
                     /locus_tag="RD486_000578"
     CDS             complement(16056..16535)
                     /gene="rlmH"
                     /locus_tag="RD486_000578"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDT7662336.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            16963..18252
                     /locus_tag="RD486_000579"
     CDS             16963..18252
                     /locus_tag="RD486_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDT7662337.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(18291..18896)
                     /locus_tag="RD486_000580"
     CDS             complement(18291..18896)
                     /locus_tag="RD486_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HDT7662338.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(19101..19565)
                     /locus_tag="RD486_000581"
     CDS             complement(19101..19565)
                     /locus_tag="RD486_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7662339.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(19587..19907)
                     /locus_tag="RD486_000582"
     CDS             complement(19587..19907)
                     /locus_tag="RD486_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDT7662340.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(20051..21130)
                     /gene="pepA"
                     /locus_tag="RD486_000583"
     CDS             complement(20051..21130)
                     /gene="pepA"
                     /locus_tag="RD486_000583"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HDT7662341.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            21330..21680
                     /locus_tag="RD486_000584"
     CDS             21330..21680
                     /locus_tag="RD486_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDT7662342.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            21903..22850
                     /locus_tag="RD486_000585"
     CDS             21903..22850
                     /locus_tag="RD486_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7662343.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(22907..24325)
                     /gene="pepV"
                     /locus_tag="RD486_000586"
     CDS             complement(22907..24325)
                     /gene="pepV"
                     /locus_tag="RD486_000586"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDT7662344.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            24474..25319
                     /locus_tag="RD486_000587"
     CDS             24474..25319
                     /locus_tag="RD486_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HDT7662345.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            25323..25763
                     /locus_tag="RD486_000588"
     CDS             25323..25763
                     /locus_tag="RD486_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDT7662346.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            25813..26007
                     /locus_tag="RD486_000589"
     CDS             25813..26007
                     /locus_tag="RD486_000589"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662347.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            26143..26828
                     /locus_tag="RD486_000590"
                     /pseudo
     CDS             26143..26828
                     /locus_tag="RD486_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(27236..27925)
                     /locus_tag="RD486_000591"
     CDS             complement(27236..27925)
                     /locus_tag="RD486_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662348.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(27900..30029)
                     /locus_tag="RD486_000592"
     CDS             complement(27900..30029)
                     /locus_tag="RD486_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDT7662349.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(30077..31414)
                     /locus_tag="RD486_000593"
     CDS             complement(30077..31414)
                     /locus_tag="RD486_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HDT7662350.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWGLL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(31666..32025)
                     /gene="rplT"
                     /locus_tag="RD486_000594"
     CDS             complement(31666..32025)
                     /gene="rplT"
                     /locus_tag="RD486_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDT7662351.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(32078..32278)
                     /gene="rpmI"
                     /locus_tag="RD486_000595"
     CDS             complement(32078..32278)
                     /gene="rpmI"
                     /locus_tag="RD486_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDT7662352.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(32350..32874)
                     /gene="infC"
                     /locus_tag="RD486_000596"
     CDS             complement(32350..32874)
                     /gene="infC"
                     /locus_tag="RD486_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDT7662353.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(32918..33043)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            33194..33826
                     /locus_tag="RD486_000597"
     CDS             33194..33826
                     /locus_tag="RD486_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDT7662354.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(33828..34733)
                     /locus_tag="RD486_000598"
     CDS             complement(33828..34733)
                     /locus_tag="RD486_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7662355.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(34818..35477)
                     /locus_tag="RD486_000599"
     CDS             complement(34818..35477)
                     /locus_tag="RD486_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7662356.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            35793..36737
                     /gene="mvk"
                     /locus_tag="RD486_000600"
     CDS             35793..36737
                     /gene="mvk"
                     /locus_tag="RD486_000600"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HDT7662357.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            36730..37707
                     /gene="mvaD"
                     /locus_tag="RD486_000601"
     CDS             36730..37707
                     /gene="mvaD"
                     /locus_tag="RD486_000601"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HDT7662358.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            37720..38805
                     /locus_tag="RD486_000602"
     CDS             37720..38805
                     /locus_tag="RD486_000602"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HDT7662359.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            38802..39866
                     /locus_tag="RD486_000603"
     CDS             38802..39866
                     /locus_tag="RD486_000603"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDT7662360.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(40115..40918)
                     /locus_tag="RD486_000604"
     CDS             complement(40115..40918)
                     /locus_tag="RD486_000604"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HDT7662361.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIAGSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(40938..41780)
                     /gene="kduI"
                     /locus_tag="RD486_000605"
     CDS             complement(40938..41780)
                     /gene="kduI"
                     /locus_tag="RD486_000605"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HDT7662362.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(41796..42803)
                     /locus_tag="RD486_000606"
     CDS             complement(41796..42803)
                     /locus_tag="RD486_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDT7662363.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(42810..43454)
                     /locus_tag="RD486_000607"
     CDS             complement(42810..43454)
                     /locus_tag="RD486_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDT7662364.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(43554..44312)
                     /locus_tag="RD486_000608"
     CDS             complement(43554..44312)
                     /locus_tag="RD486_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDT7662365.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(44439..45590)
                     /gene="fucO"
                     /locus_tag="RD486_000609"
     CDS             complement(44439..45590)
                     /gene="fucO"
                     /locus_tag="RD486_000609"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HDT7662366.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(45672..45983)
                     /gene="rhaM"
                     /locus_tag="RD486_000610"
     CDS             complement(45672..45983)
                     /gene="rhaM"
                     /locus_tag="RD486_000610"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDT7662367.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(45985..46830)
                     /gene="rhaD"
                     /locus_tag="RD486_000611"
     CDS             complement(45985..46830)
                     /gene="rhaD"
                     /locus_tag="RD486_000611"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HDT7662368.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(46844..48100)
                     /gene="rhaA"
                     /locus_tag="RD486_000612"
     CDS             complement(46844..48100)
                     /gene="rhaA"
                     /locus_tag="RD486_000612"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HDT7662369.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(48097..49557)
                     /gene="rhaB"
                     /locus_tag="RD486_000613"
     CDS             complement(48097..49557)
                     /gene="rhaB"
                     /locus_tag="RD486_000613"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HDT7662370.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            49710..50579
                     /locus_tag="RD486_000614"
     CDS             49710..50579
                     /locus_tag="RD486_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HDT7662371.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(50705..51604)
                     /locus_tag="RD486_000615"
     CDS             complement(50705..51604)
                     /locus_tag="RD486_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7662372.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(51769..52593)
                     /locus_tag="RD486_000616"
     CDS             complement(51769..52593)
                     /locus_tag="RD486_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7662373.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(52604..53899)
                     /locus_tag="RD486_000617"
     CDS             complement(52604..53899)
                     /locus_tag="RD486_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HDT7662374.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(53915..54394)
                     /locus_tag="RD486_000618"
     CDS             complement(53915..54394)
                     /locus_tag="RD486_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDT7662375.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(54400..55428)
                     /locus_tag="RD486_000619"
     CDS             complement(54400..55428)
                     /locus_tag="RD486_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HDT7662376.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(55445..56551)
                     /locus_tag="RD486_000620"
     CDS             complement(55445..56551)
                     /locus_tag="RD486_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDT7662377.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(56780..59377)
                     /gene="adhE"
                     /locus_tag="RD486_000621"
                     /gene_synonym="adhC"
     CDS             complement(56780..59377)
                     /gene="adhE"
                     /locus_tag="RD486_000621"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDT7662378.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(59682..60062)
                     /gene="yajC"
                     /locus_tag="RD486_000622"
     CDS             complement(59682..60062)
                     /gene="yajC"
                     /locus_tag="RD486_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDT7662379.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(60159..61304)
                     /gene="tgt"
                     /locus_tag="RD486_000623"
     CDS             complement(60159..61304)
                     /gene="tgt"
                     /locus_tag="RD486_000623"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDT7662380.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            61522..62220
                     /locus_tag="RD486_000624"
     CDS             61522..62220
                     /locus_tag="RD486_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDT7662381.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(62388..65027)
                     /locus_tag="RD486_000625"
     CDS             complement(62388..65027)
                     /locus_tag="RD486_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7662382.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLEGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(65646..66677)
                     /gene="queA"
                     /locus_tag="RD486_000626"
     CDS             complement(65646..66677)
                     /gene="queA"
                     /locus_tag="RD486_000626"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDT7662383.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            66870..68045
                     /locus_tag="RD486_000627"
     CDS             66870..68045
                     /locus_tag="RD486_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7662384.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            68049..68690
                     /locus_tag="RD486_000628"
     CDS             68049..68690
                     /locus_tag="RD486_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662385.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            68687..69604
                     /locus_tag="RD486_000629"
     CDS             68687..69604
                     /locus_tag="RD486_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7662386.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            69601..70272
                     /locus_tag="RD486_000630"
     CDS             69601..70272
                     /locus_tag="RD486_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662387.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(70813..71301)
                     /locus_tag="RD486_000631"
     CDS             complement(70813..71301)
                     /locus_tag="RD486_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HDT7662388.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(71502..71768)
                     /locus_tag="RD486_000632"
     CDS             complement(71502..71768)
                     /locus_tag="RD486_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDT7662389.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(71768..72031)
                     /locus_tag="RD486_000633"
     CDS             complement(71768..72031)
                     /locus_tag="RD486_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7662390.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            72507..72692
                     /locus_tag="RD486_000634"
     CDS             72507..72692
                     /locus_tag="RD486_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7662391.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(72834..74657)
                     /locus_tag="RD486_000635"
     CDS             complement(72834..74657)
                     /locus_tag="RD486_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDT7662392.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(75255..77960)
                     /locus_tag="RD486_000636"
     CDS             complement(75255..77960)
                     /locus_tag="RD486_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDT7662393.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(78266..79213)
                     /locus_tag="RD486_000637"
     CDS             complement(78266..79213)
                     /locus_tag="RD486_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HDT7662394.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            79403..79672
                     /gene="rpsN"
                     /locus_tag="RD486_000638"
     CDS             79403..79672
                     /gene="rpsN"
                     /locus_tag="RD486_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDT7662395.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(79848..80210)
                     /locus_tag="RD486_000639"
     CDS             complement(79848..80210)
                     /locus_tag="RD486_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7662396.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(80221..81342)
                     /locus_tag="RD486_000640"
     CDS             complement(80221..81342)
                     /locus_tag="RD486_000640"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDT7662397.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(81358..81708)
                     /locus_tag="RD486_000641"
     CDS             complement(81358..81708)
                     /locus_tag="RD486_000641"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDT7662398.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(81838..83349)
                     /locus_tag="RD486_000642"
     CDS             complement(81838..83349)
                     /locus_tag="RD486_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7662399.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(83671..85023)
                     /locus_tag="RD486_000643"
     CDS             complement(83671..85023)
                     /locus_tag="RD486_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDT7662400.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(85176..86252)
                     /locus_tag="RD486_000644"
     CDS             complement(85176..86252)
                     /locus_tag="RD486_000644"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDT7662401.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            86448..88193
                     /locus_tag="RD486_000645"
     CDS             86448..88193
                     /locus_tag="RD486_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDT7662402.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(88473..88910)
                     /locus_tag="RD486_000646"
     CDS             complement(88473..88910)
                     /locus_tag="RD486_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDT7662403.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(88894..90267)
                     /locus_tag="RD486_000647"
     CDS             complement(88894..90267)
                     /locus_tag="RD486_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662404.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(90589..91077)
                     /locus_tag="RD486_000648"
     CDS             complement(90589..91077)
                     /locus_tag="RD486_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662405.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(91099..91701)
                     /locus_tag="RD486_000649"
     CDS             complement(91099..91701)
                     /locus_tag="RD486_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7662406.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
     gene            complement(91770..>92657)
                     /locus_tag="RD486_000650"
     CDS             complement(91770..>92657)
                     /locus_tag="RD486_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HDT7662407.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT        27018 a        19429 c        16521 g        29689 t
ORIGIN      
        1 cttttaaata ggagaaaaaa atgaaaaaaa acaaaaacca aataatagat atcattttta
       61 tgttatttct aagttttgct tacgtcatcc ctctattcat gtctaaggga atctatcata
      121 gtgtcaatca ggatacttac tttcatttat ctcgaatcat aggactagat aatgtatgga
      181 gttctccagt aaacttcaat aacttcgatc atcatggaac aatgatgaat attttttatc
      241 catggcttac tctttatcca gcttttttat tttataaaat gatgggaaat cttgttttaa
      301 gttataatat ctactatttt tttatcactt ttttaacaat ggtcgtttct tatttttcta
      361 tgaaacaaat aaaaaacaat cgttatattt cgctgttatt ttcgattatt tatacatttt
      421 ccgcctatcg tgccattgac atattccatc gtgcttcatt gggagaagct gtcgctttaa
      481 catttttgcc tttgatacta atggggtgtt acgaaattta tattagagat taccaaaaat
      541 ggtactggtt gtctattggc atgacgctag tagtgtatac tcatttactt tctgtcgcta
      601 tggtttctgt atttattgga ggaacgttgt ttctttcttt ttatttttgg gaccaaaaaa
      661 tcgctagact cttaagtctt ttaaaagcta ccgtcctcac ctttttttta agtgcgggat
      721 tcttaattcc ttttattcaa caatctagag cacaagaatt gaaagtccca ctgggaaaag
      781 aattaagtgg tatggctcct agtgatatgc tgacacatat tttaaataat aactataaca
      841 actatactat tggattattc ttatttctcg gattgattgg tgcttttatt tttataaaaa
      901 aattaactgc tgatgattta tttattttct ttcttggtgt atttgttctt ttttgttcaa
      961 ccaatttatt tccttggcaa ctttttaacc atacaccagt taagagtcta caatttgtct
     1021 ggcggttaaa tggtttttct tctttattta tagcctatac gatgagtata gtgatctatt
     1081 atattttttc tactaaaaat aattcatgga aaataatggt ctttacgttt cttgcactaa
     1141 tattgcatct ctcaggagta agcaattcta tccatgctaa caaagattca ttaacactta
     1201 tagcacctga agacgctgtt gctatagctg aaaattacaa tcatactgat tatgcaaaca
     1261 aagagtcaat ctatcatcct gatatgatta ataatgatca atatttacta ggtaaccagg
     1321 aaataaatcc aacaactcat tttatgagta acaaacttac aattgaatta gataattcga
     1381 ataataaaaa tactgtcttg acgacaccta tttatcgtta taaagggcaa gtggcttcta
     1441 ttaatggcaa actagtacaa acaaaattat ctaagtttgg cacaactgaa ttaactattc
     1501 ctccaggtat aaataaagtc gttattactt atcagtacac aaaactagca attgcttcaa
     1561 gatatttatc tatcgttact ttgattttat ttttacttta tcgatttact ttttctaaac
     1621 aaaaacaacc gagaagagaa gtacaacatt ctcactagat ttttatttaa gaaagacttt
     1681 ttagctgtac acataaacag gctaaaaagt ctttttttat atttctttaa tttgcttcat
     1741 acattattta acatcgatat ttatactgtg aaacatgcgt ttcatccatt atcaaagtat
     1801 ttttatcgat aataaacttc atccaaaaac agaccttgtg cagggacggt ttctcctgca
     1861 tgttgccgca ctttgctttc aaatatttca tcgattgttt ctatcggcat ggcacctgtg
     1921 ccgatttcta gtaatgtccc catgataatc cgcaccattt tatataagaa tccgtctccg
     1981 acaaaagtaa aatgaagcat ttctcccttt cgttcgatag ataattcatc aatcgtacgc
     2041 actgtggatt tttttgattt tttcaatgca gaaaaaccaa tgaaatcatg tgtacccact
     2101 aatttttcgc aagctgcatt cagcttgtcc atatccaact cttgagggaa ataaaagctg
     2161 tggtttcgct caaatgctga aggaatcacg ttgttccaaa cataatagct gtattttttg
     2221 cccaccgcat tatatcttga atggaagcgc tcaggcattt cttcgattct tttgatgaca
     2281 atatcccgcg gaaggtaacg attcataaag tcgatcattt ctgccagtcc aatttctgtg
     2341 tttgttttaa aatttgctac ttgtcctcgc gcatgggtgc cagcatctgt tcttcctgat
     2401 ccaataattt ctatctcttc atttgtcatc tgatgcaata ctttttcgat ttttccttga
     2461 atggttttat cgtcatctcc aagtctttgc catcctgaat atctttttcc gtcatattcg
     2521 attgtcaact tgatgtttct catattttag tggctcctct gtcttccatt tggtcttctc
     2581 tctacctttt taagattgta gcacaaaata tagctccttg cttctctaag acagaagcta
     2641 tacaagaaaa ctgtggaaat atatatttca gaaaaacaaa aaacagccac cggatgaagt
     2701 atccgctgac tgttcaattt gacggctcaa gttttactgt ttgagatgca agatactcaa
     2761 ccaggcaatg ggcacataat taaagaaaaa actgattctt tggcaaaaac ctattttatt
     2821 cagtaatggc caagaattta tagaaggaat tcttgccagt ccataaatcg ccgcaaaaag
     2881 caaactgatc acagacagtc caaggtataa gtggcttacg tccatttgcc cattttttcg
     2941 atagatcaag aaaagaagaa ctggaaacaa taaaaaacca ctgtaaccta aacctgatcc
     3001 gatattatgg acccatgtcg agacattcca cgaagattca tgggtattga tactgaacaa
     3061 acctgtaaag atacaatcac ctataccata gaacgcgatg gctgctgtaa ctagggtagc
     3121 taacacacga gatgtactaa caaatgcagc atacaatgca ggcaatgaca ggatgaaaaa
     3181 gatccctgaa accacagacc aaataagaaa cgcttttctt acaggactgg aaacctctcc
     3241 aaatacactg atcacgctct tcatttgatc taattcagga taatacaatc ctaatacgta
     3301 cggagtcaaa aaatcactca gcacgcctaa taataaaaag aaaaaaccaa atttacgtaa
     3361 aaaatccatg atacgcctcc aataacaatt acctatgctt ttaattgtta ttataaacga
     3421 ctttatcttg atttaacaga aacctctatt tacacgaaca tctatataac tcattaaaaa
     3481 ctcgaatcat tttaaaaata ctaaatatct aacgttcaac gttcacttaa tccatctaaa
     3541 caatctttca atttgatttt ttccccactt cttttacgcg cgcctagctc tcctattgca
     3601 gtaaacaaca gatcacttga cgaatttaag gcagtttcca ttgaatcctg gataacaccg
     3661 ataataaatc caataccgac gatttgcatc gcgacatcat tagagatacc aaacaaacta
     3721 catgctaatg gaatcaataa cagtgaaccg cccgcaacac ctgaagctcc acaagcagct
     3781 aaagcagaca aaatacataa aaggactttc aaaacaaaag gtgcttcaat ccctaaagaa
     3841 tgtacagcag tcaacgtcat caaggaaatg gtaatcgcgg caccgcccat attgatcgta
     3901 gcacctaacg ggatcgatat ggaataagac tcttttgtca atttcaatct ttcagccaac
     3961 atcatgttta tcgggatatt tgcggcagaa cttcgggtaa agaaagcggg aagtgcgctt
     4021 tctttcaaac aaaagaaaat caatggatag ggattttctt taataaacaa aaacgtgagg
     4081 aatgggtaca caactaatgc gacaaacagc atcgtaccga tcaaaacaag taaaagctgc
     4141 agatactctg ccaatccagc gattccagtc gtagcaattg attgataaac caatcctaaa
     4201 atccctatcg gagcaaatgc aataatcact tgtacgactt gtgacaacgc tatagatatc
     4261 tgatccacca actcttttgt cgattctgaa cgtgctcgaa aagctagtcc caacaataca
     4321 gcccagaata agacgccaag gtaattcgca tcaataagag attgaacagg attttgtgtg
     4381 acattcgtca acatagtaga taaaacactt tccaaacttt gcggtgcttt ttcagatact
     4441 gtttcttgta aagtaatagg aacagtaaaa attgaactta caataactgc tacaagtgca
     4501 gaaagcaatg ttcccactaa atataagatc aaaataggct tcacgaatgt cttattccca
     4561 attttatgct tggcaattga cgccatcgtc aagaaaaaaa ccagaatagg tgcgattgcc
     4621 ttcaagcaac tgacaaacaa cgttcccaat attgaaataa atgtccatgt ggggaaaaag
     4681 ataccaaaca atattccgac taaaatacca acaacaatac gttgaactaa cgacatatcc
     4741 aaaaacttct ctaacaaatg accacccttt cacaatttta acaatcattg tatcatttta
     4801 tgcaaagaaa ctaaaggtat aattttctaa aaattctaac aatacaaaca accatttctt
     4861 gctaattttg tactttttct gtctacacgt tgttttttga gatattctaa gttaggatgt
     4921 tattaatggg caacttatca ggaaacgttt tcttatgttt ttgtccaatt tttttgtgag
     4981 gtgtttattc ttgaaaaaaa taaagaagga gagttatggc ttcctgacaa tctttgtcgc
     5041 ttgtataatg atggttttac agcgtatatt gatttcagca gtcactattc ctacatatgc
     5101 aacaaaccct ggtcgattct acatctatac atttttacaa acttccgttg ttattggtgc
     5161 aaatttgatc ccactttaca tgggttacca atatcaaaaa atcgcccgtt taaaagtttt
     5221 acattattta agtcgttttg cctttatatt cctaatagcc acactagttt gcaatatctt
     5281 tttttacgta caagctggca gcttgaatat tcgtgattat tggcttatcc taacacctat
     5341 cagtcagaat tactttactt atgctgtttc ttgtactttg cttttttgta gtattcctta
     5401 tacagttgga tttttaaata aattatcgaa aacaacaatt aaatatctac tattattttt
     5461 aacaattgga ttagttggct gctctactct atttaataaa gacccgtttg cattacagaa
     5521 tggacagagt attttatgga ttttttattt atttttaatg ggttatggtt tgaaagaatg
     5581 gaactggaaa gaaaaggtcc gctataagct tcctcaagta tttatcagct tgattgtttt
     5641 attcggtttg attattttga tgacacaaat ttcactcatc atcagaggaa atacagatac
     5701 agcgctgagg ttttctaaac catattctct cttcgcaatg tattatactt tctcttcgtt
     5761 tttattttta gaaatgctat ctgataaatt aggtataaaa ggaagaggaa attttcttgc
     5821 tgtatttttg attgtcactc aagttatatg taatttccct ttagtttctt atcgcgtatc
     5881 tacatttatg aaacgtgaat ttccaaactc agggaaggca tggctgataa atatcgggca
     5941 gttttttatt tgatatttat tagcagtgtc cctcctagtt atctttttat tttatataca
     6001 aaaaatccgt ttcattcatc gtttcatcga atacttcgct tttgattcga ttgaacaatt
     6061 aactcagcgt tggaaaaaaa gaattcattg gctttttgtt cataaaagtt attttttagt
     6121 tgcagcattt ttttactgct ttaccttcgt gcagattttc gttttagaac caaaagaagg
     6181 ttggaaagaa actatccagg ttgccttaaa aatatttact cagcgacaag cacccatgat
     6241 cctgacaatc atcattatta tgggattttt cttcttacta ttgttgattt ccaatcgttt
     6301 ttggtacgcc ttgactgcta ccttgatcat taacttactg ctcactattt cgacagtaat
     6361 caaaatggaa atgcgggaag agcctgtctt tccttcagat ttaaaaatgc tgaccggatt
     6421 gtcagaacta ttatcgatgg ttagcccagt cttattaatc gtgggcggat tgatccttct
     6481 cctattattg attactagta ttattgtaca acgtagacta caaaaacagt attccttgaa
     6541 gattcattgg aaacgtcgat ttatcagtat cgctgtatta ttaggatgtt tttcgggtgt
     6601 ctttttcatt aatcacaaaa attcgccttc tttcttgctg tttaatttat ttaaagtaaa
     6661 caagactttc tttaaccagc aaggcgccgt aaaagataac ggaccagtca ttcaattcct
     6721 aaacaatatc gacattaaaa tcatggaaga acctgctggc tattcgaaag aaaaaattaa
     6781 tggaataatg aaaaagtaca acacaaaggc agatgaaatc aaccaaacaa gaagtgactg
     6841 gttaaacaat cagacgatcg ttctcaattt aagtgaaagc ttcagtgatc ctgcacgtgt
     6901 ccctaatctg acagtaccta cagaccctat tccttacatc aaaagcatta taacagaagg
     6961 aacaggagga ttgatgttat ccgtcggtta tggtggcgga acagctaaca tggaatggga
     7021 aggactgaca ggcttgagta tcagtaacct gtctgcttcg ttagttacac cttataccca
     7081 gctagtggag cgtcagaaaa taagtccaaa tattaccgat ctattcgatg aaaaaatagc
     7141 catccatcct tttacagctg ctctttatcg cagaaaacaa gtgtttgata aatttggttt
     7201 tgacaggttc tattatttag acagtccgga taaattaact tatacggata aaatagaaca
     7261 aagcccacgc atatcggatg attcagcata caaagaaacc ttgaaagctt tacaaagcaa
     7321 tacggaaacg tcacaattca tccaattatc cactatgcaa aaccatatgc cttatgatga
     7381 ttactatagt gaattgaact acactgctga aggaactgct gtcattccta atagaagaaa
     7441 agaattacaa acttatatgc aaggccttca ctataccgat acagcagtaa aaaaattcat
     7501 ccaagaaatc gacaaaatcg ataaaccgat tacctttgtt ttttatggtg accatttacc
     7561 cgcaatctat agtgggaatg attcgaaaaa atatggatta gaacagcacc agacagatta
     7621 tttcatttat aacaacaagt atagtcgtga acaagcagct acgttaaata aagaagttgt
     7681 tgctcctaat aactttggtg ctatggctct tgagcatgcg aatatcaaag taactcctta
     7741 ctatgcgttg ttgacagaag tatctaatca tctacctgca ttaacaattg atcctacaga
     7801 aagcttgtct aatcgtttta atggaaaaca ggtctttgtt acagaggata gtcaaattat
     7861 ccaagaaaaa aatttaactg agaaacaaaa agaaattcta gaagattatc gtctgataca
     7921 atatgatctt gttgcaggta accagtacag tgcaacatgg gcgacacaaa aaataaaaga
     7981 ctaacaaata aactgagcaa ggggttgtga taaaagacat gtcacaaccc cttgtttatc
     8041 tcattaattt gcttgtccat aaacgatttg attaaagcca tttttcaatt cattattcgc
     8101 tgtctcgttg aagtaaagat aattatcggg attcccctga ttttgttgtg tcaccaatac
     8161 ttttggctga ttttgctgaa acccgaatag atagacgtgc tttttcagat atggttctgt
     8221 ctctgcatcg gaatagacgg ctgtgatttg atagtctgct tgacctgtcc cactttctga
     8281 ccattctgca gaaacaggca ctccaccaat agccatcttc cactccccgt tcaaaatagc
     8341 ttgagggact ttaagaccat ataagtccac actcatttga ttcgtataac ttttgtattg
     8401 ttgtcccatt gtttggcccc atttggtcat aaatgcctct aattgtgcgg atttgtctgc
     8461 attccacagt gtttgttcaa cttgttcgct gctttctgaa gaggaagatg aagcctctac
     8521 agaagaactt gaagtagatg tttgagttgt ttcagtcgtt ttggaagact ctgacgaagt
     8581 agaggtatct gctgtttctg tacttgctgc agttgacttg ctctctgtgc tagttgttgt
     8641 agtagttgca actgttgctt tcgctgtttc ttttgttgat tcttttttcg attcattccc
     8701 gttggtacaa ccagctaaca aaaaagctag accaattgtt actaaaatcc tttttttcaa
     8761 ttaaaaaact cctttcgatt actcccactt ctttattcta tcaaataagc aatgtgattt
     8821 tattgatttt tcgtattttc tcatcaatct ttcaaatctt ctaaaaactg agaagcaccc
     8881 gctgatgttg tctgtaatac atcagcgggt gcttctttta ttttaatctt cgtgattttc
     8941 caatttacct cacgctttat atttgtattt gaagaaacat agacttttag tcatcatcgt
     9001 cttcctcatc caaatcttgt cggacagttt ttccttggag tctttgtact tggtagatga
     9061 tttctttatt gaaacttaaa agttcaacaa gcaattgttg caagccatat ttttcttctt
     9121 tttcagctaa tttgattgcc cgtgtgataa agacattttg gaaatcaaaa tcttttgcaa
     9181 agttttccaa cattgttgag gctggtaaat atttgttttg accatgttcg taaatttttc
     9241 cataacgcat gacttcttct aaagtagacg gaacgatttc attttcaatc actaactcat
     9301 gagagatttt attgaaccat ctcgcttctt gatcagcata ttctgaaaaa agggtactta
     9361 attcttgcga agatgtaccc aaaacataca attgtgcttg gatcaatttc atttcttcta
     9421 atttaaaatt tgctaataca tgccccacca tggcgccagc agttggttta tgatggtcga
     9481 tatctgcttg ttttgtttct tgaacaaatt tttcttccac tatattcatt gatttacgcc
     9541 tcttttactt ttgctgattg gacttcataa cctaattttt ccacaactgc agctaattgt
     9601 tcagggtgga cttcatctgg atcaaagttt gctttgattt tgctcgcatt aaacaaaact
     9661 ttcgtattgc ttaccccagg ctgttgagaa accgcatgtt cgattttttg catacagctt
     9721 ggacaagcta gtgtatctaa ttgcataata atttttttca tcgtagttct tccttccttt
     9781 ttcttgatag tcttattcta gattacagct tccataaaaa aattgattct tatcaagttt
     9841 tacgattttt cttctttgct ttcgtgtcca aaatacaata aacgcatcgc gttaaagata
     9901 acgatcaaga tactagcttc gtgaacgaac atcccactag ccatgtaaat aaacccggca
     9961 aataagccgt tgagtaaaaa taagacgaca ccaatggcaa tcactacatt ttcacgggta
    10021 tttaaaacag ttttcttagc caagcggtag gcatgaacca acgattcaaa attagattgc
    10081 atcaagacaa cgtcactcgt ttcgatagca acatccgttc ctgatcccat agcaatcccg
    10141 atatcagccg cagccaaaga gggagaatca ttgattccat ctccaataaa agcaacgcgc
    10201 aatccttgtt cttggtattt tttcacaaat tgaacctttt cgtctggtaa taattcagca
    10261 tggacttcat caatgcctaa catatcagct acataatcag cagtcatctg attatcacct
    10321 gtcagcatca ctaactgttt tgctcctgct tgtttcaact tagctaattg ttcagcgact
    10381 tctggtcgaa tcacatctga cacacctatg atttgagtga tttttttgtc gattgctaca
    10441 ataatgaccg agctgcctgt ttgttgtaat tgatgtaaat cttgtacttg ctttggtgtg
    10501 agagaaagtt tgtgagcggc aatcaatttg gtgttgcccg cacaaactgt atgaccatca
    10561 atctcagctg tgattccttg tcccttgatt gtctgattat ctttgactgc taattgttga
    10621 aaatcaatgt ctttctcctg agcataatgg atcacggcgc gccccagagg atgatcggat
    10681 aacgtttcta atcgagccac taaagctaag ctgtcccctt catcctctgt atagttcttg
    10741 atagtggata cagcagtagt tcctttggtc aatgtaccag ttttatcaaa gacaaaagta
    10801 tcgattttgg aaaaagtatc cattgcttca ccgcctttga ctaagatgcc ccgtttcgct
    10861 ccattaccga ttcctgctac attcgaaaca ggcgcaccaa tgactaaagc gccaggacaa
    10921 ccaagaacca aaacagtgat tgctaaacga aaatcacgac taatcagacc aacaaccaac
    10981 gcaataagta aaacggttgg agtataatac tgagaaaatc gatcaatgaa tttttccgca
    11041 tgggatttgg tatcttgtgc ttcttctact aattcgataa ttttggcaaa ggtcgtatca
    11101 tctccgacct tagttgcttc aatcgtcacg tagccatctg ctaaaatcgt tccagagaag
    11161 acttcatctc cactgatttt gacgacttgt cgtgattcac cagtcactgc ggcttcatcc
    11221 gcataccctt tcccgtcaat gactcgtccg tccacaggaa tagctccacc agtttttact
    11281 aagacgatat cgccttcttc cacgtcatcg atttccactt cttcagtcgt tccatcttct
    11341 tggacaacac tagcagtaga tggggccatc tcggtcaaag ccttgattga ctcccgcgtt
    11401 ttggtcaatg ttttttgttc cagatagcta ccaaacaaaa acaagaatgt aacgatagct
    11461 gactccttgt attctccgat cataaaggca ccaagcacag caatagtaac gagtaaatca
    11521 attgagataa ctttgacttt cactgcctga tacgcatgga tcataatagg tatgaccgca
    11581 ataatagaag ctatggctag agcaatgtta tagaacaaga caaaaccagt aaattttccg
    11641 ataaaaccaa aaataatcaa cacagctgat aaggcggtga tatgatttcg atgctcttgg
    11701 atccactttt gtaatttcat ctttctccct cttttccttt cattcttacg agactaagta
    11761 tagatactta tccatcataa aaaattgacc actatcaagt ttagtcaaaa aggcggtttt
    11821 cttttggtag aatacactac aaaaaatagt tagcaagaag actcactaaa agtgatcttg
    11881 ccaactattg tcgtttctat cgaaattttc attgaatgat tttcctgtac agcatacatc
    11941 ggagatctat ttctttatct aagattttta tcttgctaat tttttccttt agtctttcaa
    12001 atccacgtcg ttcatagaat tgatacgtac agccactatc tgtaaaaagg aatatttctt
    12061 ttcctttctc tcttttttca aattctgtta gcaacttggt accgatgcct tttgttttca
    12121 aatcaggatt tgcagctaaa aaaatgatct ctccatctgg cgaatgcttc tttaaatatg
    12181 ctgcaagcat ttgttcattt gctgtctcgt aagctccttt actttcttta gcaaatatat
    12241 tttgtaaaaa atcgaatatc ttaacatata tttgctgtcc aaaagaacga tgtttctttt
    12301 tttctccttt tatctccgcc agcaaaacac ctgccaactc gtcctctgca tacaaagcaa
    12361 gaatttgagt tgctcgattc aactccatat acaaaaaata tcttccgtaa agattcagca
    12421 gaagttcatt ttccatatat ctctcaaagt tcattccttc aacagcaaaa tagatagctt
    12481 ttttgtaatc tttcttttct aagggtttaa aagttagttt catcatttcg cctcctcaac
    12541 ttcaatgatt gtgttatact tacattataa tagacacagt gtctactatc tataatcaat
    12601 catctataag tttgtcgatt aagcgacagc tttgctttga tatgtcggat aaggagatag
    12661 gtaaatgaaa aagacagata gacgcgtcaa aaaaacagaa aaagctttgg ctgaaacact
    12721 atccacatta ttagtaaata aaaagattca agcaatcact atacgcgaac taacagaaac
    12781 ggcagatgta catcgttcga ctttttatac acattataag gatatctatg atctatatga
    12841 tcaattagaa agcaactttt ttcgggatct aaatgaaatt ctctcttatg atccagccca
    12901 tagctatgag gaactataca ctcgcttgat tgactatgtt tacgcaaata cttttttata
    12961 tcgcttattt atcctcaacc atggtgatat ttcgtttcag aagaaagtta aacaagttat
    13021 tgaagaaaac tatctgaaca tatggctata tgaagacaag aaaacgatta tcacagaaga
    13081 aatgagattc tttactacgt accacgtcca aggttgtcta tccgttctca atcggtgggt
    13141 agaaagcaat tacaagtact ccaaaaaaga attattagaa ctcttacaga aactgaatga
    13201 tcacatagag aaaatcatgc cttgaataaa aacatactaa gcttagttaa gaagaaccgt
    13261 aaccttctcg tataacaact gaatcttatt tagccaaatt gtttactgaa gattttttga
    13321 gtaaaatttc tataattcct acttattgaa aagtagtttg tagtgctgct tctccctctc
    13381 taagtgatat atcttgttgt accaatcaaa ttcacctcat cattaataaa ttacttttag
    13441 gctaatttat tacaacttat aggttgaagc tgtaaccaat ttatagtcat attatatttt
    13501 tatcatccag tttattgaat tcttctcgtt tacctcaatt cattttcaag gggaatcagc
    13561 tcatcatcta acattttacg ccatgctcgc ttcatttctt gtgggtattt aaatggtttc
    13621 gcttctggat gtttggcttt atatccttcg taatccttac tgttgataat tgctttcata
    13681 ttaggaattg gatcttcacc tggcatatat tgcagattag aagcatgtaa ttttttctca
    13741 gaaacaaacc actcattgga aaagacatga atcaaatcat cacttacttg tgtaaaatag
    13801 cgacgtttaa tgacaaagat atcttcattg ctatctagtg taccttcatt tctttgtgct
    13861 taaattcaaa gataattttc tcaataaaga tttttgattc cagtaagatt cctttactcc
    13921 ttttacaaca tagcgttgtc ctttgttttg aaacatcttc ttcccctctt tgccattaaa
    13981 aatagcccaa ttctctataa agaagattaa gcttcattat tataatataa agtttaaatt
    14041 tggtttatta cttacttttt cttattctct agtaagctaa tattgaaaaa aatgtaatca
    14101 gatcattatt tttatatgtt gtaacttcct gataagaaaa ctaattaaaa gaaagaggta
    14161 actacataaa ctaattaaaa aagctaactt catagttgga ggataaatgg aagaaacttc
    14221 aatgattgtt tctccttgtg ttccttcaat cgacactagt cctattatca atctctcttt
    14281 tttgtccatt tacttttgcg actgttcccc aataatcaaa tacaggaagc gttatttttt
    14341 gtcctttaga ttcatgtact gtatagacta ttttcgaatc catcacttga taaggcatag
    14401 tatgccattc cttgccaatt cttacttcat gattctgcaa atgttctttg tattgtaatg
    14461 cttccgtggg tgcatagtca taaagtcctc cgggaaggag tgtcgtgtaa cgaataagat
    14521 tttcttgatt cattaccaag tgatctctct gagtgacaac tttatgttca tagtttgctt
    14581 ttgttgcagc agatacagcc aacagtaata aaacaattgc cgttatatta actacttttc
    14641 tttgcttagc tgatgtgctc ttcatgaaaa cgaacgataa aatcaacgag ccaaacagta
    14701 cttgaaagcc taagattcgc caaggaaatt gaatcatttg aatgggtgta ttttgtaata
    14761 aagaccatgg aaaaaatttg gtggataaga gccaagagac taccgcacta aggtaaatca
    14821 ctttttcttt gcgattaaat cctttaaaaa agaagagtgg acagatcaaa gaaataatac
    14881 caatgattcc taccgtaaag gttgtcaggt cattattcat cgcaccaatc aaactatccg
    14941 agacatttaa tgcttggtgt tgtaaggtcg ttttatctgg ctcattaatc gattgaacca
    15001 tgatttgtcg gaacatcgga taccaaaagt atgctgttaa aagaatcgtc attcctactg
    15061 cctttgacaa ctccacaatc aaccggatgc tttctttttt tcttgtttca cttactacaa
    15121 agccgcctaa gactagtaag ccaacggcta ttacactcat aaaagtggaa agaacatgtg
    15181 tataaatgag taagctcata ctgactgcta atggaattgc acatggcttt ttctcataaa
    15241 tcagtgcgta agcataatac ataactatcg gtataaccgt aagtgcaatc gcttcagcaa
    15301 tagcagaacg atgataaata tcaatcgtac ggtacccata aaatgtatat aaacagctaa
    15361 atataaaagc cgcatcgatt ctttttaaaa attttagtcc ataatgaaac atcagcatga
    15421 tagtacaaac attcaatagc caaacatata agatataact aacgattaaa ttattactta
    15481 tccaataaaa aatgactgcc ggaaaaaagg tcaagtaggg ataaaaataa ttcactccgc
    15541 tcccataatg attaaacgtc gtaaaattga ttggaccaga aaaaattgaa gataaccctt
    15601 tgactctagc aaaatggaag gcaatatccc ccgatgtaga aatagtatga acatttctaa
    15661 aataattgat tgaataaagt ccagcaataa ttgctaggag aatggacaat attatttttt
    15721 tctttacttg cattacttaa ttatatactc ctttcatgga ttgctttatc tagtataact
    15781 taaattttaa ataaatcgtt atttattttt actctcactt aaaaaagcac taaaattata
    15841 agagagggag gtaatggtct gaacaccaag aattgttcca acatcgaatt gcttaactaa
    15901 tgagttcaaa gcttaattat gtggctctta tatttaccga gcgtggattg cgatctcttt
    15961 agcgaaacaa acatctttca taaaaaaaac agccatatcc gctttcttgg atatgactat
    16021 ttactactac tttactatct ttcattcttc ttgtctcact tatgataagg cgcccccgca
    16081 ttgatccgga aggcacggta gatttgctcg acaaggatca gacgcatcaa ttgatgtgga
    16141 tacgtcattt ttccaaaaga gatctgagca ttgcttcttt tcatgacggc ttcgctgagt
    16201 cctaaagagc cgccgataac aaaaacaagg tggctttttc cttggatacc taattggtcg
    16261 atttgtttag caaaagattc acttgtagga tttttccctt caattgctaa ggcatagacg
    16321 tattcttgtt ctttgatttt cgctaagatc cgttcccctt ctttttcttt tacttgtctc
    16381 atttgcgctt cgcttaaatt ctccggggct ttttcgtcag gaacttcgat caattcgatt
    16441 tttgcatagg cattcagccg tttgacatac tcattgatac cttggatcag gtatttttct
    16501 tttaattttc ctactgagat aattttgata ttcatgtttt ctctcctttg gtcttcatgc
    16561 tcactttgtt tattataatc aattttttcg tctatatgtt tattttggct atttttgtta
    16621 aaaagatttc cccaacagtt atgcacaaca tccacaggtt tatccacaga aaacagtgtt
    16681 attttacctt atttcatcac attcattagg caaacatacg ttttataaga atttatccac
    16741 tttatacaca ggctgtggat atgttttatc ccttattttt ccaatcctat ccgcgtagtt
    16801 ttacacagta tctgtggaaa aagaaaatca aatattttca tctgaaaaca atgatttttc
    16861 ctaaagtttt tcataaaaag ttcacagtct caaagtagac taaagtcaac aaataagact
    16921 atactaacag tagataaatg aatgtaattg gaggaggaac acatggatag aaaaaatgtg
    16981 acaccaaaga tgaaaaaaag taaaaataat agcctctggc gtaagttagg tctggggctt
    17041 gttggaggga tcgttggagg actactgaca gctggcattt tttatgcagc gatgggcact
    17101 ggcaacaata gttctactgc tacaagcggc aatcagaatt ctgccggtga aacagttgtg
    17161 gaaaatgtca aagtcaatgt agattctgat atcaccaaag cggtagataa agttcaagac
    17221 gctgtcgttt ctgttatcaa cttacaaagt caaaaccaat caagcggttt tggcggacta
    17281 ttcgggcagc aagaagaaag tagcagctca gatgatagta atttggaagc ttatagtgaa
    17341 ggaagcggcg tgatctacaa aaaagacggg aatactgctt atgtagtcac gaataatcac
    17401 gtagtagatg gccagcaagg tcttgaagtc ttgatgaaag acggtacgaa ggtaaaagct
    17461 gaattagttg gaacagatgc ttattcagat ttagcggtgt tgaagatcaa ttcagacaaa
    17521 gtcgaaacag ttgcctcttt tggtgactca agtgctctga aggttggtga gcctgcgatt
    17581 gcgattggtt ccccactagg atctgaatat gcaaattctg tcacttcagg aatcatttct
    17641 tccttgaacc gacaagtgac aagtacgaat gaatcgaacg aaacagtcaa tatcaatgcg
    17701 atccaaacag atgcagcaat caaccctgga aattctggtg gtcctttagt taatatcgaa
    17761 ggacaagtta tcggtatcaa ctcaagtaag atcgcaagta cttctgaatc tacttctaat
    17821 gtaagcgtag aaggaatggg atttgctatt ccaagtaacg atgtagtgaa tatcatcaat
    17881 caactggaaa aagacggaaa agtgacacgt ccagctctag gtatcacaat ggtcgactta
    17941 tctgccgttt ctactcagca acaagaacaa atcttgaaga ttccttcatc tgtaactaac
    18001 ggtgtcatcg tgacaaatgt ccaaacagct acaccggctg aaaaagctgg attgaaacaa
    18061 tacgacgtca ttactaagat cgatgacaaa gaagtttctt ctggtgtaga acttcaatct
    18121 gctttgtata agaaaaaagt gggagattct gtcaaaatca cttactatga aggctcgaaa
    18181 gaaaaaacaa ctactgttga attgacgatc gatcaatcgg cattaaaaca aaatcaaaat
    18241 agtgaaaatt aataaaaaag aggttgtgac aaagacttgt cacaacctct ttattttgga
    18301 aatgcttctc cgactacggc atcctcaggc aatactaaga ttcctttttt tgctggagca
    18361 tttggcaaat gcaattcacg agcggaacag atcattccat agctatctac ccctcgcaaa
    18421 gttcctggcc agatcatcat tccatctggc atcatagctc ctggttttgc aacgacaact
    18481 ttttgtccag cttcgatatt gggtgcaccg caaacgattt gcaatactgt accattgtct
    18541 acttctgtct cagtaatcga taaatggtca gaatcaggat gtgggacgca tgtttttacg
    18601 tacccgacaa cgatcttcgg ttcatgatca gcttcaagct gttcttcgaa tcctgcttct
    18661 ttgatcaatc gattcaattt cgctaattcc tcatctgtta agcttacttg gccgttccct
    18721 tcgattgtta gatgatcgga gatatggaaa aagttccaag caacaacttg accttgttca
    18781 tctttgatcc gagcaacatt ccatttgcgt tcaacagtgt tttctgttcc tttatcgtcg
    18841 gctataataa ccatcaaggt gtctccgacg tgtgctttgt tataagcaaa aatcatgttc
    18901 tttcctccat tatcctttgc tgagatttat cttaacaaaa aattgcattc actgcatgaa
    18961 atttttttca tgctttattt ccgaagaagc ctcttctgga acaccattta ttcgtaacaa
    19021 gggactgtga caagactttt gtcacagtcc ctttactgtt ttagttaatt gattaaaaag
    19081 gtcgtacaag ttccacttgc ttaattactt ggctgttctt cttcgtcaga aacgatcaag
    19141 acatcacaag gtgaatgacg tatcacgtag ctggctacac ttcctgtcat aaagcgttcg
    19201 actgcattta gacctgactg cccaaccatg attagatcga tctcatattt ttttggcaat
    19261 ttgactgcca tggattcacg aacagaacca tatgcaataa ttccttctat atttgtgtaa
    19321 tcaacagatt tcccatattc tttacattct tcgatcattt ccttggctgt ttcagtttgc
    19381 tgatcgacta gattttgatc aataggtgca tagcccataa agttataaaa ttgctgatcg
    19441 attacgtttg ctacatatac tttcccatta ttacggcgag ccacttctac cgcttttttg
    19501 aaagcagcaa gtgcttgttc actaccgtcg atacctacta aaatattctt atattcttga
    19561 ttcatcttga cccctcctaa cagatgtcag ccttttgtta cactttctag gaacgattcg
    19621 atttcctgtt ttgttttacg atctttattc actagacgac ctaattcttt tccgtcttgg
    19681 atcacgacaa aacttgggat accaaaaatg ttccattcag cggctacatc tatgtacttg
    19741 tcacggtcta cttcaataaa ttgccaatca gaaaagtcat tttcaatttc aggcatttgc
    19801 ggtttgataa aacggcagtc tccgcaccag ccggcagtaa agaaaaatac actctttcca
    19861 gtttctacgt agcctgctaa ttcttctaaa ctatttggga taatcattct ttgtcctcta
    19921 ctttctgttt atgtattttt caattaaatt atacaccttt ctttcgaact aacaaacatt
    19981 gatcctcttt ttataaaaaa aatctggcaa aaagcaatct tttgccagat tttatagttt
    20041 cactatcgca ttattttccg tatacgatcg tatttactgt tgatttatcc aaacctttca
    20101 gtgtttgaat caacatttct cgtgcagctt caaaatcgcg aatactgaac atcgtttgat
    20161 gcgtatggat ataacgtccc actacgccaa tcactgtact tgggattcct tcgttttgtg
    20221 tatgagcagc acctgcatct gtaccgcctt ttgaaacaaa gtattgataa gggatattgt
    20281 ttgtttcagc gatatccagc aagtactcgc gcaaacgagg aagcatgatc aaacctggat
    20341 cttggatacg catcaatgta ccttctccta aatgtccgaa tgtgccattt ttcgtcactg
    20401 tatcatctgc tgcagagcag tctactgcaa agaacagatc tggcttgaat ttattgacag
    20461 aagctttaga accacgcaag cctacttctt cctggacatt cgcgcctgca atcaatgtat
    20521 gacctaatgt ttcattttgc aacgcttcta aagcttctaa taccattgta cagccatagc
    20581 ggttgtccca tgatttactg ataatattct ttccgttggc tgttttgatc gtttcagcgt
    20641 aaggaacgat tgtgtctcct ggaaggacac cgtaactcat tgcctcttct cttgattcaa
    20701 acccagcatc gaacaaaata tcggttactt ctactgattt ttgtccgctt gttcctcgca
    20761 ataaatgtgg gggaacggaa gaagaaatac atggataatt cttaccagta gaggttttaa
    20821 gtgtaaaacg ctgagcagaa acaacgtaag gattccagcc gcctagaggt acgactttaa
    20881 aaagcccgtt ttcttggatt tgtgtcagca tgaatccgac ttcatccata tgtgctgcga
    20941 ccattacacg gggtgcatcc gcttcttcat gatggcgcag accaaaaatg ccgcccaaac
    21001 catctaactg taactcatct accagcggtt ccatatgact ttccatataa gcgcgaacat
    21061 cttgttcaaa accgcttgtt ccttgtaatt ctgttaactc tttgattcgt tgaaatgttt
    21121 tttcttccat atgctattcg tctaaatttc agactaaact cctctcagac ttatattgat
    21181 ctgcggataa aatatgattt tttctgcaga ccgatcgtat ttattatagc ttattttttc
    21241 tggtagcggt tatttatttc aaagaaaata tgagagtgtg gtaaaataag cacaaggagt
    21301 aacaagtgag aagaaggagg tatgtccaca tgtatgaaga aagcgaacta agctatttta
    21361 aaggcgggtt agcagttgga atcggtctag gattattgag cggggtagct tcaacgattt
    21421 ggtatcatcg caaaaaagta ttgtcagcag accaagtact tgaaaatatc aagtcatctt
    21481 ttctaaaaga aggtgcaatc gaaggttctt ggatctcttt tgaaaaggaa cctattagga
    21541 aattcgccgt tcggtcgagt gcttatcggg gaggtctttc tcgaatagaa gatggcgaaa
    21601 ctgtttatta tgaattttta gcagatgctc atacaggaac cgtattagaa atttcaagaa
    21661 aaaaaggtgc aacagattaa tacgtcaaaa aagtgagaga acgaatacgc acccactatt
    21721 caaaagagag gtatcatgtc cttcttttgt agtgggtggt tttttagata gagctttcca
    21781 aacatatatt ccagtatttt ctttttaaat aaatgatatt tagcgggaaa aactagcatt
    21841 tcctttgatt atgaggtatt tttaatttag cttttgtttt ctatagttaa ggagagtgaa
    21901 aaatggaaca acaagaaaaa attgctgttc tgattccttg ttacaatgag gaagcaacaa
    21961 tttcaacagt cattgcagac tttaaacgag aattaccaga agcagatatt tatgtctatg
    22021 ataataattc gaccgatcga acatacgaat tggccgttca aggtggagca atcgtaaaaa
    22081 aagaacctcg tcaaggaaaa ggaaatgtga tccgccaaat gttctttgat atcgatgccg
    22141 actattattt aatggtagat ggcgatgata cttatcctgc agaagctgta catggtttgc
    22201 tcgagaaatt acgttctggt gaagcagata tggtcattgg tgatcgccta tcaaatggaa
    22261 cctactttga tgagaataag agacctttcc acgattttgg aaataacctt gttagaaata
    22321 caattactag aatgtataaa acaaaaattc ttgatgtcat gaccggctat cgaggattca
    22381 atcgtatctt tgtcaaaagt tttcctatta tgagttctgg ttttcaaatc gaaacggaat
    22441 tgacgatcca tgctttagat aaaaaattca agttcgttga aatcccaatc gattatcgtg
    22501 atcgtcctga aggcagcgaa tcaaaattga atacattctc tgacggattc aaagtgatca
    22561 tgatgattat taaaatgttt aaagattata agcctttgct tttctttggg atttggacca
    22621 ttttcttctt tttatttgga ttggtcacgg ggattcctgt gattcgcgaa tatatgctga
    22681 caagctttat tacacgcatc ccttctgcga ttttaagtac tggattgatg actttagcac
    22741 ttctttcatt agtaacaggg ttgattttgg atacagtcgt cacgaacgct aagaaagaat
    22801 atgaattgaa tctatatcat gtttatcatg aataccacag tagaaagtaa aaaaaggatc
    22861 aagactgcaa aaataatttg caattcttga tcctcttttt aattaattat ttcgccaaac
    22921 gatagatggc atctgcatag attgctgttg ctctgaacaa gtcatcaaga ctcataaatt
    22981 cgtttgcttg atgcattgta tcagtatatc ctgggaacat cgctccataa gcaacgccac
    23041 gtttcaacaa acgtccgtaa gttccgccac cgatgatttg ttcgtagcct ttttctccag
    23101 tgtggtcttc atagacttgc aataatgtag ccaccaatgg atcatccatt ggtacgtaat
    23161 gtggttccat tacgcgagca cctcgagtaa ctgttgcgcc ttcttgcccc actgtttgtt
    23221 cgatgtcact ttgcaatccg tctactgtta caccttttgg aaaacggaaa ttcatattga
    23281 tgaagttcgc ttcctctgta ccattttctt caaaagcaaa tagtccagca ttcattgtca
    23341 atttgcccat tttttcatct tcataagcga ctcctagttt ttctccataa aaatcttcat
    23401 ggacataagc agctgctaca tggataaatt gtttagcaga tcctaggaat tcatagttat
    23461 ctaagaacaa tgccaagaaa gaacctgcat tgataccaga ttgtgggctt gcaccatgtg
    23521 cgcctttacc aactaattcg atttttacat acgtattgtc cgcttcaatc gttccgctta
    23581 ctggatttgc ttcgatgaat tggtaaaatg cttcttccat cgcgatagct gcatctgcac
    23641 ttggtacttg aagtgctgca gttgctgttc ctggcaccat attttcgcga agtccggaaa
    23701 caaaagattt caagacataa tctcctgcat tgtcgccttt gaagcgtaaa gctaaagaaa
    23761 catttccttt ttcaccattg atgattggga attcagcatc tggtgagaaa ccaaaatctg
    23821 gttcttcttc atgttcgaaa taataagcca tatcgcccca gccgctttct tcatcgctgc
    23881 cgactacgaa gcgaactttt tttgatagtt tcaagtcaag ttctttaatg atcttcatcg
    23941 catagtaagc tgccatactt ggacctttgt catcgcttga tccgcgtgca aagatctttc
    24001 catccttgat tactggttca taaggatctg tgtcccagcc atctcctgca ggaacgacat
    24061 ccatgtgtcc aaatatccct agcgtttcgt ctccttcgcc aagatcaata tgccctgcat
    24121 agttatcgac attttttact ttaaatccat cacgttcgcc ataagctaac atatgtttca
    24181 atgcgtcgcg aggtccaggt ccaaatggtg catctggtgt tacttttgag tcatcgcgct
    24241 cgctgttgac acgtaaaaga tttttcaagt cttcaagcaa gtcttcttta cgtgcttcta
    24301 cttctttttg ccaatcaatt gtcataaagt taatcctcca cttatttaag tcttcgtgtt
    24361 catgatacca caaattacag aaaaaaatag ttcaaaaaat ctgacaattc cttttcttat
    24421 ctgtttttct ctaaaaaaaa tatacgctat aatgagtaaa aggaggtttt tagatgctga
    24481 taaacgaaca actagtgaaa agagtcatca cacctcgtcc aaaaatttca cataaaggaa
    24541 catttggacg tatcgttttg attggcggca atgaacaata tggcggagca atcattatga
    24601 gtgctttagc tgccgtacac agcggagcgg gtctcacgac tgtagtaact gatgaaaaaa
    24661 atcggagtgc tcttcacagt catctgccag aagcaatgat tgtagtttgg acggatactg
    24721 accagtttct ttccgtaata aagcaagcag atgtactctt gattggtccc ggattgggta
    24781 cttcttctaa gagtttggaa cgtttcaaac aagtactaga aaaccaatca aaagaacaat
    24841 ggctggtgat tgatggctct gctttaagtt tacttgctgc taatcatctt ttgctaccct
    24901 atcccgaaca aactgtactt acacctcatc aaatggagtg gcaacggttg agttctctac
    24961 cgatacaaga acaacgggat aaagaaaaca aaaagaagca acaggaaatc ggtgctgtgc
    25021 tcgttttgaa aagtcatgag acaaaaattt atggtcacca gcacttctac accaatcctt
    25081 taggttctgc tgctatggca acgggcggca tgggtgacac tttagctggg atgatcacag
    25141 gatttttagc ccagtttcct caaaatgacc aaacgattgc agcagctatt tatcttcata
    25201 gtttcattgg agaccagctg gcaaaagaac aatatattgt tttgccgaca caaatcagcg
    25261 aagcacttcc gaaatggatg aattattttt gtaaaaaatc aatggaaaac gaggcatgag
    25321 tcatggagaa atttacaggt tatgtgcgag aaccttttta ttatgaaaca gatcaaatgg
    25381 ggattattca tcacagcaat tatatccgct ggtttgaaga ggctcgggta gccttattgg
    25441 tacatctagg gtttccctat aaaaaaatcg aagaatctgg gatcatcatc cccgttctgg
    25501 aagtaaattg cagctataaa gaaatgatcc attacggaga aaaagtgagc atccatccaa
    25561 ctatccaaaa gtatacgggg acacggttgg attttagcta cgaaattgtg ggaactgaag
    25621 acaaaaaatt aaaaactact ggcagtagta aacactgttt tttactttct gattcgcaac
    25681 gattagtgaa gctgagcaaa gtcaatccgg agttagatca gttattccaa gcgtacgctt
    25741 ctttggatga tgtaaattct taataaagac cgtctaagca tttttcttgt attgtgtcga
    25801 gtagttcgta taatgaaaag aaaaaagcag gtgatcccca tgtatgtcgt taaagtaatg
    25861 cacggttaca tcgataaaac tggctgtcgc actcgggaaa aaaacttaga caatctgctc
    25921 attttcaaag acaaaaaaga atccgaagct tttgctaaaa gaatcggcgg tcgtgtcaaa
    25981 ccgatccaag aggtacgacc agattgattc aatatttttc ttttcgaggc tctaataggc
    26041 atgcctatca gggctttttt tgcagactgt gtttttatgc ccacacgatt tgtaagcgat
    26101 ttatgttata atagattata tctgcataga aaggaaggtt aaatggttat caataatttg
    26161 caacagcaag cttatgaatc tatacgtaaa caaatcattt attccgagtt agcacctgga
    26221 agtaaaatct ccgataaagt gttagaagaa caactagcta tcgggcgtac accgattcga
    26281 gaagcactga tccaactgcg caatcaagag cttgtaaaaa ccattccaca gtccggcact
    26341 tatgtttcaa aaatcgatat ccgatctgct tcattagccc gttatacgcg ggaaaagttg
    26401 gaaaaaccga tcctgcaaga atgcagtgcg aaaatgacca agcaagatca agctaaacta
    26461 gaaaaaatac tagaacaaac cgatcaggca gtaatcgctc aaaataaaaa agcttttttg
    26521 atttggatac tgattttcac cgaacttgtt atgaaattgc tggaaaacga gaaatttggg
    26581 attggctaga aagttatagt acgcacttga accgtttcag atggttacgt ttgacgattt
    26641 cagaattaga ctggggtcga gtattagatg aacatcagac aatgcttcaa tcaatgattg
    26701 atcataactt tgatgaagtc ggatttcttt gcacgatgca tttacatatg attatcgagg
    26761 agcaagaata cgtgattcat aattaccccg attattttga agatattcag gacagaccca
    26821 tcaaataaga ggttttggaa tcagcgtttt gacctgagta ttagagaaag aaacggcaaa
    26881 atagttcctc atattttgcc gttttttttg agctaatacc gagggtcagc tgattgcaca
    26941 ccgtttattg agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaagta
    27001 aaaatagctt cttatgtttt taacttggct ggacttatta ccgcagatgc aagcttttga
    27061 acaccgtttt ccaagaggtc gtgagcctgc cgttcatctc cgagtcacaa ggaacaattt
    27121 caaaaaacag cttctcatgt ttgttgaata ttttgacttg tgaccgagga gttgacagga
    27181 gaacatcgtt tattcggaaa aaaaggactg tgacacgact tttgtcacag tctctttatt
    27241 tgtaatctaa atcatactcc gtacatcttt tttctatttt ttttatttct tctaagatcc
    27301 cttggctacg aatttcatta tatggccaaa gtaagactgc ctctaataca taaggcgaaa
    27361 aatcgctttg attcatctct tttgaaaaac tcatcgctgc tatctcgctc aatgcacgaa
    27421 tgtttgattg atgtgtataa aaaggcaacc gccacagcac aattttttcg ctttgcgtat
    27481 aaattccctt aacagaagct tcgatgtggt gaaatagttc atgtccaata atcaaagctt
    27541 gcgctgtttc tttagagatc gaagctagtc ctgaacattt taatttttct aacggctccg
    27601 tcatcaatcg aatcccttca tcttctgcat aagttgcaaa agtgattcgt tcgtttattt
    27661 gctctgattc acaggaaacg attggaacag ccatttgttc acaaatttct cctacatcgg
    27721 caaaagggta cttttttttg atgctacatg ccgtttcgat accacaatcg attgattgtt
    27781 gtataagaat tttctgcttg gacaaaggaa tctttttcca aaataaatct cgccgaaact
    27841 ggtagaatcc ccaaatttct tcggggatct gttgtaattc gtttagtaac tcttctaact
    27901 tatgtttgtt tgatatttcc ggcaacgacg atcacttctt cctccggttc catagtagat
    27961 acttccagat ccatcaaaag ctgtagttgt tccagatccg tcgctgtaaa atcagagact
    28021 cttgctccta agcagagata aaattctggt cgggcaatca attcagtttg ataaactgcc
    28081 atatcttccc aaagttgttc gacagctgtc atataattgg ctgcagttgt tttcatacat
    28141 gaagcatgtc cacgttggac cttgataaat cctttttgat cgatgatccg aagacttcca
    28201 gcattttttg aacgattctg ttcgccgcat acataaaaga aaggtgtatt ttccaataag
    28261 caaacttcat ttttatttaa tcgcatatcc tctgcagcaa gctctagtgc ttcttctgtt
    28321 gtgatctcct tggttagatc ggttgctttc acttccgtag aaccagtagc gatagccgtt
    28381 acttttgaag tctgtggatc gatttctacg tggacttcga tcgattctgg tgtagcgcct
    28441 gattcaatcg ctttattcat cgcttcattt ttcaacgatc gtatatcttc tttacttggc
    28501 gaagggatga tacgttctac aacatctcgg accattgcaa gtgctacacc aatagaagaa
    28561 atcacttcgg cgttttcagg aatcgaatat ttcacaccca ttttattact aaagtaagta
    28621 atcaatgagg cagcgccgcc ccctacacct acaagagaaa tctgatcttt ctccaagtga
    28681 tacttgtctg ccaattctaa aatcaccggt tcaatcttag cataggattt ttccatgatc
    28741 tgttctgcga tgtcttcaac cgtcgtatga caataatcag ctaatgcttg gatggctttt
    28801 cgtgcagatg ggacatttcc ataagaaaaa tgttcttctt gcactaatcc aaggacattg
    28861 gctgcacatg tatttgtaat agtcacttct tctccgtctt ccatcactac cttgacgtaa
    28921 tcagcagggt ctccttcttt aggagagaaa aattcaacct taggaccttt gattttttct
    28981 gtctccgtaa atactgcata atctagaccg gcaatatgtg cagaacgtgg accgacatcg
    29041 atgattcctg actgattagc ccgtaccatc gaaccgcctg ccacacctag aacccgaaca
    29101 tctaatgaag agatatatgt tgggtggcca cctacaattg aataatcgat tgctggacgt
    29161 ccatttttaa tgaccccgat attggttgtt gttccgccta cttcaaaata aacaccatta
    29221 gacgctctca agtacatcaa agagcccatg actgatgctg ctggaccgga aagcatggtt
    29281 aaaacaggtc gttttttcat ttcattgatt tccattactc cgccgtctcc gcgcataatc
    29341 atcaaagaaa cattgacccc tgcttctcgt acggaatctt ctgtagaggt tgccgtatct
    29401 agcatttttg gtaaaataga tgcattgatt gctgctgtcc gagttcttct tgtcaatcca
    29461 tataattttg tgatgtcaga agccatcgtt gtagggatcg attttaccga tgctgcttca
    29521 taaacaactc gttctggttc cccattatct actccaaatg ccatagaaga aaccaagacc
    29581 tccgctcttt ctctttctaa agaagaaatc gtttctgaaa cacggtctac atttaagtgt
    29641 ttgacaggta agaatgcatt gacaatctct atttttttct tattccctaa atcgatatcg
    29701 ttcaatctag tttgtcgttt tgctaaaaaa ccttctaatc caccttttgc catcccgatt
    29761 acgccgactt ttgctacgtc tccttcaatc agtgcattag tcgcttgtgt ggtagaatgt
    29821 gcaacaaaca caacatcttc tggactgata ttattttcca gcaaacaatt ttgaaaagac
    29881 tgaacgacac ctgcggctac tccacggaca tcatcgtggg ttgttttcac tgaagatttt
    29941 ccgatgattt cgtgcgtcgc attatcgatt gcgactgctt tcgtatgtgt accgccaaca
    30001 tcaattccca ttcgcacaaa acgtttcatt ttcttttcct ccattcatct aatcgttttt
    30061 atcgacgttt tgtttactag gcgttcccgt acaataagaa cgtgatcagg cataagatcg
    30121 ctccgatgat ccaaccagtt gggatggatt tcttcatata ttctcgagaa gttacttttg
    30181 tataacctaa tccccaagca acccaagatt gtgtaatatc taaatgctga ggagcaatcg
    30241 ttgtgattgc aaataacggg aacaaaaagg ctggcgacat cgttggatta acagctaata
    30301 cgacagctaa aatagctgag cctgaaccga ctagattcat tggaccgcgg aaaaatccta
    30361 gtggtgtcaa tatagcaaat acgattgcca agactaatgg tgattgcggt atccaatctc
    30421 caaaaatagc tgaaaaataa ggagaagcat acgcagctga attattgaac atcgctaagg
    30481 tcatcaagaa accaaccatt ggcgcaacat ctactgcgcc atctgtaaat aatttcgcaa
    30541 actgacgaca gatttcttta taacctccgc gcaattttcc agtaaacagc aatccccaga
    30601 tacctgctag aataaaacct aagatgattg gaagatctaa aagaacgacc cctaaaactg
    30661 gtaataatac ggctaaccat gagatcattg gtgcgtcgcc accttcagct ggtacgtttg
    30721 ctgccattgc atagcgtttc tttttgttca ttgatatatt agcgaccgtt agtaccacaa
    30781 ctaagcttac aatcatccca atcataccaa tttggaaata gtcattataa gtatagcttt
    30841 cagccgctgg attgaaacca gcataaatcg tttgatattg tttgaaattg acgatattag
    30901 caaagattcc agccataatc gagcccataa atgagaacag tgcaaccggt actgaaatac
    30961 ctaatgacat caagattggc aacacaataa ctgcaataga aatcactggt ccgattcctg
    31021 tcatcgacat gaatataaca gcggttacaa tacatagtaa gctcatcgtg attcttggct
    31081 tgtcccctcc aagttcaact acctttcgaa tcagggtagc tgcgattccg ctatctacta
    31141 gaacacgccc gaaaaaggca ccaaagaaga catttaccaa gatcgatttg gcgtactcag
    31201 ctggccccgt cgtatagata tgcgtcaaca catcaattac tccttgccct tccatcgccg
    31261 ggtttggtga aaacgtgttt ccgactagcg ctaatcccat ccatacagta gccatgatgg
    31321 caaagccgac catcaagttg tagcctttta cacagtacca gaccatgaaa aagaatgaga
    31381 taactaacaa aataccaata ataatatcac tcatgttatt cctccgtcca ttttgttttt
    31441 ctgataagca aactaatata tcagtcaaac tcattctaac ttatgtagtt agcgctttca
    31501 ttaaagggtg accataaatg ttcagttttc aattaaaaaa ccttaattat gctattttag
    31561 acttatacgt tattgtcctg tttcatttga tggaggattg taaataaaaa aagaggaaag
    31621 aacataactt ttcgttatct tctttcctct ttataattgt ttagcttatt tagccaaagc
    31681 ttcttttgct tggtcagcca atgcagtaaa tgctgctgca tcgttaacag ccaagtcagc
    31741 taacatttta cggttgatgt cgatttcagc aactttcaaa ccgtgcatta attttgagta
    31801 gctcaagcca ttcatacgag ctgctgcgtt gatacgagca atccacaatt tacggaagtc
    31861 gcgtttcttt tgacgacgat cgcgatatgc gtagttgtat gaattcatta cttgttcttt
    31921 tgctgtttta aataaagtgt gttttgaacc gtagtaacct tttgctaatt ttagcactct
    31981 tttacgacgt ttacgagtta ctgttccacc tttaacacgt gccatgtata attcctccta
    32041 ataaaaataa atcttcagat tctgttattt gtacttctta tttcattttt gctagttgtt
    32101 ggcgaatacg tttgaagtcg ccactagaaa ccatgcttgc tttacgcaat tgacggcgtt
    32161 gtttttttgt tttgccgtgg aaacggtgac ttgtaaacgc gcggaagcgt ttcaatccgc
    32221 ctttaccagt acgtttgaaa cgttttgctg atccgcggtg tgttttttgt tttggcatga
    32281 ctatatttcc tcctcaaaat ctttcgttat ccgactatcg gctgtccaac agccagttag
    32341 tcattcaaat tacttactgt cgtttttcgg tgccagcgtc aagaacatgc tgcgtccgtc
    32401 cattttcgct ttttgttcca ctgttgcaat atccgcagtt tcttcagcta agcgattcaa
    32461 gactttttga ccaatttctt tatgggtaat ggcacggcct ttgaaacgga tagaagcttt
    32521 cactttatcg cccttttcca agaacttacg tgcattacga agttttgtat tgaagtcatt
    32581 caagtcgatc gtaggactta agcgaacttc ttttacattg atcacttttt gttttttacg
    32641 cgcttcgcgg tctttctttt gttgttcgaa acggtattta ccgtagtcca tgattcgcgc
    32701 aactggtggt ttcgcaccag gggcaactaa cacaagatcc aagtttgctt gttctgcaat
    32761 attcaatgct tctgcttttg tcttaactcc taattgctca ccatctgaac cgatcaatcg
    32821 taactctcgt gcacgaatgc cgtcgttaac catcatatcc tttgctatgg tcattcacct
    32881 ccaaatatta tgagagaaag aaaagcttac cgaataaacg gcaataaaaa aacgagttct
    32941 cttacagaac ccgcgcgtac ttcacctaat agaaccagtg aaaactatct agcccagtga
    33001 cattatcaac taaggcgaga agcgggtgct tctgctttta tttctcaacc atcatagtat
    33061 agcaaaaact aatctttttg tcaatgtttt tcatacagtt tgtcttcctt ttctgaaaat
    33121 gattagatta gcagactttc tagcagtgat tcccgcttct ttgctatact aaagaaaaac
    33181 gaggtgaacc cacatgaaaa aaatcgaacc tattccacct tctcttcctc ttcttacaaa
    33241 gggagagttt tatttagaag atgaggagat cttctctggt cttctgatca acgggggtga
    33301 ccaaagctat ctcgatgcca aaaatatggt attaagagag agtcatatcc aaaaacttac
    33361 gatgcaaaaa acagttttac gtcattttga atgcagtaat gtcatttttg aaaaatgtga
    33421 tttttccaat ctggagtgga ttggtggcag tttccaccaa gtcgtgtttc atcaatgtaa
    33481 attaacaggt acgaattttg ccgaaagtta tcttcgagac tgtactttca ctgattgtat
    33541 tgcttcgatg gcttccttta gtagtacaaa cttgaaagct gtctccttcg atcattgtca
    33601 attagaagac agcgaatttt atgaggtcac ttggaaaaac ctttttttgt ctgacaatca
    33661 gttgaccggt tcgaactggt ttcgaacttc tctgaaggga ttagacttta cgactaattt
    33721 cttcacagca atcgctttat ctcaagattc tttggcggga ctaatcgtca accaagagca
    33781 agcacttgtg atcgcccaag cccttggttt gcagatcaaa gactagatca acgaatccgc
    33841 cgccacagtg caataagcat ccaaatagat aagaccaaac tgatgatcaa ggcgattccc
    33901 catccgaaaa cggaatgggt aaagggtaac tggagattca ttccgaagaa tcctgtcaca
    33961 atagttggaa cggtcaagat cagcgaccag accgtcaaaa atttcatcgt gtcattcaag
    34021 ttgttattca gcaaattatt ataagtgcca gagagctggt ctaaaatctg cgaagctaag
    34081 ttcgtcattt caactgcttg tcgtgcttcg atcagcgcat cgtccaactc ttctttttcc
    34141 ttttctgaca acttgcgata aatagccaat gccttgattt gttctaaaag tactacattt
    34201 tgttttgttc ctgtaactaa gtaaaccaaa ccgatctcta aatctgaaag ttgcagcaga
    34261 ttcttgttcg ttgttttttc tcttaatttc agattaagcc gctgacgttc actattcact
    34321 tcctcgatta aaggaaaaaa ggaatcagaa atcaaaaaca atgtacgaaa caataaactg
    34381 tatacactca tgtctggcat tcgttccaaa agcgatcgaa ttagtcgaat cacgtactcg
    34441 gtattcggcg tggtaaatgt aaacaaaccg tcttctttta aaataaaagc gataggacta
    34501 gtttcataat gattatcgac tttttgctgg tgcggaacat ttgatacaag cagtaacgct
    34561 tcatcaaaag aatcgtactc tacgcgcgcc cgttcatttt tatctagaga ataagtcagc
    34621 atctcgtcac taatgccata ttcttctttt aagtttttaa cagctagcac atcgttttgc
    34681 tgtacattga tccaaaaatt acggtcttga ttaaaatagt gtttttcccg catactctat
    34741 cctcctgaca tttgtttcca gtataaagaa aaaagtcgct caaataaagg tttacccttt
    34801 atttgagcaa ctgtaaatca aatggctact ttggtttggc gaatctctgc taatttttct
    34861 tcgatcattt tcaagacttc ttcttttgct tgaggatctt ccacaaaatt atagcggtct
    34921 ccatcgattt ggatttttgg actttctttg tattcttcat accattgatc gtaacgtctg
    34981 ttcaattctt tgtaataatc gtatagactt ggatcaaagg acaattgttc atacgaacga
    35041 ccacgttttt cgatacgctc caacatcgta tcaaaagata cacgaatatg aactaataaa
    35101 tccggatgtt ttttatgggc agcataggga agttcttcca tcatgttttc cagcagttca
    35161 tcatacacac gaacttctgt ttctgttgct cttcctagat ctgcatttag atggaaaagc
    35221 agtgaatctt cataaatcga acggtccaat acattattgt catctttcat tgcttgtttg
    35281 atgcttgcaa aacgtttatt caaaaaataa atttgcagca aaaaagcata ctgttcaggg
    35341 tttgcataaa ataagggcaa gacttcatta tcatcaatcg attcataaaa tgcctgacta
    35401 tcaaagtgtt cagccatcat ttctgttaaa cttgattttc cggcaccaat tgtacctgct
    35461 aaaacgatca cgctcattta cctccagctc acttcatcac taaatattgt gtttaactcc
    35521 aaccttttta aatatacccc caatatctag tagtgtcaat tgtatttttt tctagtcaaa
    35581 gaagaaaaaa agtcaaaaaa ttcttaagaa aaaagtgttt tttctttaga aaacgtattc
    35641 ttagttttac ttctgagatg gttttagtaa aataaaggag gaatgttttt tgagaccctt
    35701 agtggacaaa aaaattcgtg aagcagcgca actcgttttg ggcgctttat tttttgctta
    35761 aaaatcactt ttacgtgaga aggagttaga ttatggcaaa ctatggccaa ggagaatcaa
    35821 gcggaaagat catattgatg ggcgagcacg cggttgttta tggagaacca gcgattgcct
    35881 ttcctttcta tgcaacaaaa gtcaccgcat tccttgaaga gctggatgca atggacgatc
    35941 aactggtttc ttcctactat tcaggaaatt tagccgaagc tcctcatgca ttaaaaaata
    36001 tcaaaaaatt attcattcac ttaaaaaaac agcatgacat ccaaaaaaac ttgcaactga
    36061 ccattgaaag cacgattcct gctgaacgtg gaatgggatc aagcgctgca gtcgccacag
    36121 cagtcactcg tgctttttat gattacttag catttccttt gtctcgtgaa atactattag
    36181 aaaatgtcca gctttcggaa aaaatcgccc atggtaatcc tagtggaatc gatgcagccg
    36241 ctactagcag cttgcagccg atttatttta caaaagggca tcctttcgac tacttttctt
    36301 tgaacatcga tgcttttttg attgtcgctg atacaggaat caaaggacaa acaagagaag
    36361 ccgtcaaaga tgtcgctcac ctctttgaaa cccagcctca tgaaactgga caaatgatcc
    36421 aaaaattagg atacttgacg aagcaagcaa aacaagcaat cattgaaaat tcaccagaaa
    36481 cgttggcaca gacaatggat gaatcacaat cacttctgga aaagctgaca atcagcaatg
    36541 attttcttaa tctattgatc caaacagcaa aagataccgg ggcattgggt gccaaattaa
    36601 ctggcggtgg acgcggtggc tgtatgattg cattagcaca aacaaaaaca aaagcccaag
    36661 aaatcagtca agcacttgaa gatgcgggtg ctgctgaaac ttggatacaa ggattaggag
    36721 tacataccta tgtttaaagg caaagcacgc gcatatacca acattgctct aatcaaatat
    36781 tggggtaaga aaaatgaaga actcatcctt ccaatgaaca acagcctttc gttaacattg
    36841 gatgcatttt atacagagac agaagtcatc ttttctgata gctatatggt agatgaattt
    36901 tatctagatg gcaccttgca agacgaaaaa gcaacaaaaa aagtcagtca gtttcttgac
    36961 ctttttcgta aagaagccgg cctctcacta aaagcttcag taatcagtca gaatttcgtt
    37021 cctaccgcag ctggattagc ctcctctgcc agcgggctag ctgctttagc aggcgcttgc
    37081 aatactgctc ttaagcttgg attagatgat ctctctcttt caagatttgc tcgacgcggg
    37141 tctggttcag cttgccgaag tattttcggt ggtttcgtcg aatgggaaaa aggccatgac
    37201 gacttaagtt cttacgctaa gccagtccct tccgattctt tcgaagacga tttagcaatg
    37261 gttttcgttt tgatcaacga ccagaaaaaa gaagtgtcca gcagaaatgg gatgcgtcgg
    37321 acagtcgaaa catccagttt ttatcaaggc tggttagatt ccgttgaagg ggatctatat
    37381 caattgaaac aagcaatcaa aacaaaagat ttccaacttc tcggagaaac gatggaaaga
    37441 aacggactaa aaatgcatgg aacgacttta gctgcccagc ctccattcac ttactggtct
    37501 cctgacagct taaaagcgat ggatgcggtg cgacaattga gaaagcaagg cattccatgc
    37561 tactttacga tggatgctgg ccctaatgtc aaagttttag tggaaaacag ccatttatct
    37621 gaggtacaag aaacatttac caaattattt agcaaagaac aagtaattac tgcacatgct
    37681 ggtccaggaa ttgcgattat tgaataaagg gagattttta tgattgaagt atctgcacca
    37741 ggcaaactct atattgccgg agaatatgca gttgttgaaa caggccatcc agcagttatc
    37801 gctgcagtcg atcaattcgt gacagtcact gtagaatctg cacgaaaagt cggaagtatc
    37861 caatctgcac aatatagtgg gatgcctgta cgttggacaa gacgcaacgg agaattagtt
    37921 ttagatattc gggaaaatcc ttttcattat atccttgctg ctattcgctt gactgaaaag
    37981 tatgcacaag aaaaaaacat tcttttatcc ttttatgatc tgaaagtaac aagtgagtta
    38041 gacagttcaa atggccggaa atatggattg ggttctagcg gtgccgtgac cgttgcaacg
    38101 gtcaaagcct tgaatgtttt ttacgcgttg aatttatctc agttggagat tttcaagatt
    38161 gcagcactag ccaatttagc agttcaagat aatggttcct gcggcgacat cgctgctagc
    38221 tgttatggtg gctggatcgc tttctcaacc ttcgaccatc cttggctcca agaacaagaa
    38281 actcagcatt ctatcagtga gttacttgcc ctggattggc caggtctatc cattgagcca
    38341 ttgattgctc ctgaagattt acgtttattg attggttgga cgggtagccc tgcctctact
    38401 tctgatttgg tcgatcaagt tcaccgttcg agagaagata aaatggtggc ttatcagctt
    38461 ttcttaaaaa atagtacaga atgtgtcaac gaaatgatca aagggtttaa agaaaataat
    38521 gtaacgttga tccaacagat gattcgaaaa aaccgacaat tactgcatga tttatctgca
    38581 atcactgggg tcgtcatcga aacgcctgct ttgaacaaat tgtgtaattt agctgaacag
    38641 tatgaaggag ccgcaaaatc ttctggtgca ggtgggggcg attgcggaat cgtaattgtt
    38701 gaccagaaat ctggcattct tcctttaatg agtgcatggg aaaaagcaga aatcactcca
    38761 ctgccgttac atgtctatag cgatcaaaga aaggaaaacc gatgaatcga aaagacgaac
    38821 atgtttcact agctaaagcc tttcatgata aacaaaaaaa cgaatttgac ttcgtacgga
    38881 tcatccataa ccctttgccg caaatagcag tttctgatgt cgatctaagt acacaggcag
    38941 ttgggtttac actaagcagc ccattttata tcaatgcgat gactggcgga agcgaaaaaa
    39001 caaaaaaaat caaccaagat cttgcaatcg tcgcaagaga agcagatttg atgattgcca
    39061 ctggttcagt cagcgctgcc ttgaaagtcc cttctttagc cgatacttat acgattatgc
    39121 gacaagaata tcctcacggg aaaatcattg ccaacatcgg tgcagggact tctgtcgaaa
    39181 gagccaaaga agctatccga ttgtttcacg cagatgcctt acagattcat ttgaatgcac
    39241 ctcaagagtt ggttatgcct gagggagacc gtgattttac caattggaaa gtacttattc
    39301 aagaaactca aacagccatt gacgtccccc tcatcgtaaa agaagtcggt tttggcatga
    39361 caagagaaac gctcaatgat ctagctgctt taggagttca tacagttgat atcagcggtc
    39421 gaagcggaac aagcttcacc cagatcgaaa acgcccgtcg ctccaagcgg gaactgagtt
    39481 atttagctga ctgggggcaa tcgacagtct cttcattgct tgaagcaaat gaagcagaca
    39541 cttctatgga aatcctagcc tccggaggta tccgcaatgc ctatgacata tttaaagccc
    39601 tttgtctcgg cgcaaatgcc gtgggtactt caggaaccgt actgacgcat ctgatgaatc
    39661 acggcgtaga agaaactatt atactgatga agcaatggca agaagagctt cgtctgcttt
    39721 atactatggt cggcgcaacg aataccgcgg ccctacacca acaatctctg atcttttccg
    39781 gaccagtgaa ggattggtgc gaagcaagag ggatcgactt agtgaagtat ggaagacgca
    39841 cagaaaagag cgtgggacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtaca
    39901 aacggcggaa gtaaaagcaa ctccttcgga aataagctga aattcacaaa aatttgaaaa
    39961 gcaattttcg tgaattcctt cttatttctt ggagttaaat gcttctgtcc cagcctcttt
    40021 tttcgaataa atgatgttta atcagctgtc cttcggtatt cgttcaatcc gctgatttca
    40081 caacctctcc actaaacagt gtactaaagc tcttttaagg ttgttttccg atataggcaa
    40141 gtatgcctcc gtccacatac aagacatggc cgttaacgaa atcagatgcg ctagaagcca
    40201 agaagacaga tggtccagcc aaatcgattg gctcgcccca gcgtgctgct ggcgtacgtc
    40261 caacgataaa ttgatcgaat ggatgacgtt caccgttttc ttgtgtttcg cgtaatggag
    40321 cagtttgcgg tgtagcaata taacctggtc caattccatt acattggata ttgtattgac
    40381 cgtattcaga agcgatgttt ttcgtcagca tttttaatcc gccttttgcc gcagcataag
    40441 cactgaccgt ttcgcgtcct aattcactca tcatggagca gatattgatg attttaccgc
    40501 cgcctttttc gatcatatcc ggaataactg cttttgaaac gatgaatggg gcatttaaat
    40561 ccacgtcgat tacttggcgg aagtctgccg catccatttc gatcatcggt gtccgtttga
    40621 tgatccctgc attgttgact agaatatcaa ctgaacctac atcttctttg atctgttgaa
    40681 ccatcgcttg aaccgcttct tcatcggtca catcgcagac ataacctttt gcatcgatgc
    40741 ctgcttcttt ataatgcgct ataccttcat caactgattc ttgattcaag ttattaaata
    40801 cgatttttgc tcctgctgta gctaaagagc ctgcaatctc aaatccaata ccatagacag
    40861 caccggtgac taatgctact tttccatcta aacgaaacat atccatacta aattccatca
    40921 ttttctctcc cttatgctta ttttaattga tccatttgca ccatatccat gtctgtatag
    40981 gtgatatttt ctccgcacat tgcccagatg aatgagtaat tgcttgtacc tacacctgaa
    41041 tggatcgacc agcttggcga aataatggct tgttcattgt ctacaactaa atgttttgtt
    41101 tcatctggtt tgcccatcat gtggaacaca cgtgtatctt cattggcata atcaaagtag
    41161 acataagctt ccatacgacg ttcatgtgta tgacaaggca tcgtattcca agcgcttcct
    41221 ggttctaaaa tcgtataacc catttgtaat tgacagcttt cgcatacatt tggatggatg
    41281 tattggtaga ttttacgttc attcagtgtc aggccttcac cagtctccat tggttttact
    41341 tggtcgatac tgatttttac atttggatat ttatgatgag ctggaacaga actaatatag
    41401 aatttagctg ggttttcagc atcttgagaa gaaaatacaa catgtcgtgt ttcttttccg
    41461 atatagtatc cgtcttgttt tttcatttct tctttttgcc catcgatctc gatgaatcct
    41521 ggtccaccga tattgatcac acctagttca cgacgctcta agaagtaatc aacacctagt
    41581 tctttgtcta atgtgatttc taattctttt tcagtaggtg tcactccacc aaagatcatt
    41641 cgatcgttgt gcgtataagt caaactgatt ttccctggtt caaatacctt ttctactaaa
    41701 aattcttttc tcaattgttc cgttgaataa tgacggatat cttctggact gtgtgtataa
    41761 cgtgtttcca tttcttgcat tttcttctac tccttctatc gaatgatttt tccagagccg
    41821 catgctaaaa attgtgcgac ttcttcttga ctaaattggt tgcagtcccc atggatcgta
    41881 tgcttcaagg cagaagctgc cgtagcaaaa tcaatgattt cttgcggaga catattggat
    41941 aaaatcccat ggagcacgcc acctgcaaaa gcatctccgc cacctactcg atccacgatt
    42001 ggggtgattc tatggacttg ggattccaca tattcatggt tcatccacaa tgtccccttc
    42061 aattcatttt cacttgctga atgaacggta cgcttggtcg aataaaacac ctgaatattc
    42121 gggaactttt cctgcatttt ttgataataa taaattagag gttgttcttc tgcttctggc
    42181 gctttctcga tacctaacaa ataaagagca tccatttttc cagctgagca gatatctact
    42241 aaaggtaaaa gctgatggat tacttcgctg gcttcttgct gtgtccataa ttttccacga
    42301 tagttgatat cgaagctgat caggcagcca gctttttttg cagcttctat cacctgtttc
    42361 gtcatttttt gccatttttt agacaaagct ggggtgattc ctgaaacatg aaatatatct
    42421 attccttgga ataactcctc tagcgaccat tccaaatgat ccatttcagc aaaacttgat
    42481 ccggcacgat catagatcac tgaggcggcg cgttcgccac taccagtttc catataataa
    42541 gtacctagtc ttgatccacc agataatacc tgtttcgtat ctactccata acattgcaag
    42601 tgctttttga ctgcttttcc caatgcgtta tcaggtactt ttgtagcaaa aatcgcttca
    42661 tgtccgtaat tagctaaaga aattgctacg tttgcttccc ctccgccata atgggcagcg
    42721 aatcgttcac ttgaatcgat acgggttccc tgctctgtgg acaatcgcaa catgatttct
    42781 ccgagtgtca ctacttttcc cataagcagc tacctcttga tttctttcat ttttgctgca
    42841 tactgttgcg cgacttccgt tactttgtca aaatctcctg tagctgcggg tgctaaaagg
    42901 ttcccaccta ctccgactgt tacgacacca gcatcgaacc actctttcat attgtccaga
    42961 ctcacaccgc cagttggcat gatattgact tgaggcatcg gcgccttgaa ggcagaaatg
    43021 atacttggtc cataagcgct tccaggaaat agtttgacga tatctacccc gcttttcagc
    43081 gctgttttga tctcggtaat agtcatacat cctggtaagt aaggaatttg atacagattg
    43141 cacatctctg ccgtttcttg atcaaaggaa gggctaacaa tatactctgc gccagctaag
    43201 atagccaagc gagctgtgac agcgtctaat actgtgcctg cgccaatcac tatttctggt
    43261 tggtctttgt agaatgacaa aagttctttg attacttgat ctgcttgagg gactgtaaaa
    43321 gtcaactcaa taccagttag accacctttg atgattgcgt ggcaagcatt caaagcttct
    43381 tctttgcttt ttccgcgtac caccgcaatc actccggcgt ttttcaatcg agataaaata
    43441 tcaatttttt tcatcttctc cacctatttc ctatttagaa attttatttt ataacttgga
    43501 aatctatacc catattatac ggcagaaaag aaaaattgca aacgcttttt tcattatttt
    43561 tgaattcttt gctcgatttc gctttttgtt tgcttgaggg cactgattat ttgttctttt
    43621 gtctcatctg ttaaacgata tttcggcata cttacactaa atgcaccaat gatttgttcg
    43681 tttttcacga ttgaggctcc tatacaaaaa atatcacgtt cgatttcttc atcgtcaaat
    43741 gcgatgtggg tttcttttac cgttttgatt tcctttttca accgtaatgc attggtgatc
    43801 gtatattctg tgtaagggat caacggatgc ttttcaagat aatcagtgta ctgctcttca
    43861 ctgaattctg ctaatacggc tttgcccatc gcagaattgt ataatggtcg ggtgattccg
    43921 atttttgaag acatgcggat cgtttgatgt tttggatcta gtttgttcac gtacaagatc
    43981 tcattgttgt ccaatacccc taagtggata gtctcatcga tcttttgctg cagctgttct
    44041 aaaaacggta aagtcaactc taccaaatcg atttgttcaa tgtttttatt cgcgtagcga
    44101 ataagctttg cacctaaacg atagtttttc tctgaatttt tatttacgta gccgatcatc
    44161 aacaaagtat ctagtatttt caagactgta gaagaggtca ttcccacacc ctttgcgatc
    44221 gtctgcaaag agacatcttg gttttccgct aaatagtcta gtattttaga ggctttgatc
    44281 aatacagttc cataaggctt tttattttcc atataatatt ctcctatttc tttataagaa
    44341 aaattatagc ggaaatacca tcaatttaaa agagatatcc agatataaac taccatttct
    44401 ctttacaggc aatttaatgt tgaagatccg cttcgttttt acatcaaact ttgatataaa
    44461 gcaatgattt cttctactgt cgtttctctt ggatttcctg gtgtgcatac atctcgcaaa
    44521 gcatcttctg caattgctgg aatatctgct tcttttacac ctaattcaga aatggtttct
    44581 gggattccaa ccgctttgct caaccgatcg atctcaccac aagccgcttc tcttacatct
    44641 tctaaagaca tttcagctgc tcctttaatc cctagaacaa gagcgatctc acggtacttt
    44701 tctccagtat attctttgtt atatttcatg acagttggca aaagtgctgc acacgctacg
    44761 ccatgaggaa tgttgtacca tgcacttaac gggtgagcca tcccgtgtac cagtcctaaa
    44821 ccgacatttg agaagcccat tcccgcaata tactgtccta atgccatttt ttctcgccca
    44881 ttttgatcgc catctacaga agcttccaaa gaatggccga tgatttcgat tgcttttaaa
    44941 tgcagcatat cagtcatttc ccaagcgcct tttgtgataa acccttcaat agcatgcgtc
    45001 atagcatcca tacctgttga tgcagccaat tttttcggca ttcccatcat catatcgctg
    45061 tcgatgaacg cgacgattgg gatatcatga ggatcaacac aaacaaattt tcggtgattt
    45121 acttcatctg tgatgacgta gttgatcgtt acttctgctg ctgttccaga agtcgttggt
    45181 atagctaata taggtaaaca tggatttttc gtatcagcaa caccttctaa actaatgacg
    45241 tctgaaaact ctggattcgt caaaataatc ccaatggctt ttgccgtatc gattggcgaa
    45301 cctccaccga ttgcgatcaa acagtctgcc tctgcctctt taacaaaagc cactccatct
    45361 tttacatttt ggatcgttgg attaggtacg atcccgtcgt ataaagcata agcgattgct
    45421 gctttatcta gaagttctgt tacttttgtt gctataccgt gctcgatcaa tcctttgtca
    45481 gtaatgacag ctgctttgcc gaatcctcgc tgctgaaatt cagggacgat cgactcaatc
    45541 gctccttttc caaaatacga tgtttcattt aaaatcattc gattactcat tttctattcc
    45601 tcctaatttg tattattttt cacaataaaa acgaaagaac cccaagcaac cggttgccca
    45661 gttgcttgtt gctacagttc aaagactggc atcaattccc aactgactgg agaggcatct
    45721 ggatttgtct ccatgatatc ttccatgtac ttccaccatt tttgattgat agatgtattt
    45781 gccatttttt cccataactt ttcatcttcg atcactaagt aaccaaataa caaacttgta
    45841 ctcggatcaa gatagatcga atagtcgatg accccgtgtt cacgaagtgc tgtacgcatt
    45901 tctggccaaa gttcatcatg tctttttttg tattcttctt gtttttctgg gtaaactttc
    45961 atgcaaaaag cttttttcac catgtcagac acctgctttc gtatgaactt cctccaaata
    46021 acctgctttt ggagtgacac caaacgcatc tgctaaatgc cacaggtttt cgtccgtgat
    46081 tgtttgcaag attggtcctt gcgctttgac gtacgtatag acttctgctg ccttttctgc
    46141 tgtctcgatc aaaccaaaga cttcatccat gtcttttcct gacccgtaga ttccatgttg
    46201 tggccataaa accaatcgag tttctttcat tttttcagct gttgcttccc caatctcatt
    46261 tgttcccgga accatccacg gaatgatgga aattccttct ggaaaaacaa ctaagcattc
    46321 cgtacacatt tgccatagcg tacgactaaa ggaacgttcg tctaattcat gcgtaaaact
    46381 catcgctaat agatgactag catggcaatg cataacgatc cgattatctg ggtctacttc
    46441 taaacgggcg atatgactca tgaaatgact tggcaactcg cttgtaggaa ggcattcgtt
    46501 ttccagcccc cacaaaagtt ccagtgtttt gccatcttca gcaactcgaa cgattccaag
    46561 attctcggca ggttcgctcg ctacattttt aaaatatctt cctgaaccag ttacaataaa
    46621 atagcatcct gctaaacggc tggcatcaaa aatcatcgag atgcggcgga tcactttttc
    46681 aggatccaag aacggtgtga tctcttcttc ttttagtaaa taagaaatat tcccgccatt
    46741 tctttcatcc catcccaagc gataaagatt cgacgtcgtt tcgatcattt ctttcacata
    46801 aggcgcttgt aaaatatcta tttttttcaa tatagccaca ctcctatttt cttaattcca
    46861 acacgtcttt ttgatattcc tggacttctt ccagccaatc caaaccaact ggaacttgat
    46921 ttttgtaaca gaaataattc catacatcgg catacgggaa atctttcaat tcttccgtat
    46981 aagccattct tgaagtaaag tcaaaagcca gctccatttc tttcaatcgc tcaactggtt
    47041 ccagcatagc tttcagcagt gctttttgtg tatttctcgt accgatgacc caagcagcga
    47101 tacggttgat cgttgcatca aagaaatcca gaccgatatt tgttttttcc aacaattcgt
    47161 tacggactaa ttctttagcg atttcctgca attcatcatc catcaaaacc acatggtctg
    47221 aatcccaacg cactggacgg gaaacatgca acatgattcc tttgctgaat aaagctaatg
    47281 aagataattt attggaaatc acttctgttg gatgaaaatg tccagcatct agacaaacaa
    47341 gtttgtcacg agtcaacccg taacccatat aaaattcatg ggaaccgact gtataagctt
    47401 cagcgcctaa accaaatagt ttgctttcta ctgcatcttg tacataccgt tcatctaact
    47461 cttctgtaaa aatttcatcg agtgattcca ttaaacgttc ccgtggggta aaacgatcaa
    47521 tcggattatc tttcatccca tcaggtaccc aaaagttatt gatacttgtt tgcccagttt
    47581 ctttcccaaa gtactccgcg attttgcggc ttcttttccc gtgttcgatc cagtattcac
    47641 gaacttcttt atctggatga gccaatgtaa agccgtcttt catcattgga tgcgaaaaga
    47701 aagtcggatt gaagtcaaga ccgatttctt ctttttttgc ccactctacc catttttcaa
    47761 aatgtttcgg ctcaatttca tttagatcga cagattcttc tgtatccaaa tagatagcat
    47821 gaaggttcaa tttgtgtttg cccggtatca acgaataagc cttctccaga tcttgtctaa
    47881 gctcttcagg tgttcgtgcg gctcctggaa aattccctgt cgccatgatt ccaccggtca
    47941 attcgccatc cggtgtcaag aaacctttga catcatctcc ttgccagcaa tgcatagaaa
    48001 ttttgatgtc ctgtatcttt tctagtacag catctgtatc tacaccgata gttgcatatt
    48061 tttcttttgc ttgttcgtaa tttctttcaa tcgtgttcat acgattactc ctttgatttt
    48121 attcacgtac cattccatcg tgttttgctt attttcatct gggtaaaaag tttcacatgg
    48181 aaacgactgt ttgattacat ttcttgcttg ttctatattc gaaaactgac ctgtactgag
    48241 catttgcatg gcaacattcc cgattgctgt ggcttcacta ggtcctgctt ctacaatgat
    48301 tccggcataa tctgctgtca attgattcag tagacgatta ttcgatccgc cccctacgat
    48361 gtgcagcttt tccaatttcg ttccagttaa gtgttctact ttgatcagct cttgtgcgta
    48421 acaaagagca agattatcat acacacaacg agcgatagct cccgatgaga cagggactgg
    48481 ctgctctgtt tcaaaacagt attgctgaat ctcttctatc atatttgggg gattcaaaaa
    48541 tcgagggtca ttgatttcca tcacttgctg cagcggtttt tcttttgcag caagctctgc
    48601 caattccgca taactgtact cgtactcttg cattcgggca acttcctgga tcaaccacat
    48661 ccccatgatg tttttcaaaa aacgcaccgt gttatgggca ccccattcat tcgtataatt
    48721 ttcagaaaaa gcattgcgag aaacattggc gatctttgtt tcaatcccta aaagcgacca
    48781 tgtcccactg ctgatataac cccaacgttc tccttgacct ggcgttccta atacagctga
    48841 cgccgtatca tgacttgcta ctgtgataaa ggtcacatct ggcaaatcat attttgaaaa
    48901 ttgttctttt tgcagatctc ctagtatcgt tcccggctct gtcaatggtg gaaataattc
    48961 cttcgagaca ccgatttttt caagaagttc tatttcccat tcttttgtcc ctgcattcag
    49021 cagctgcata gtagatgcat tagttttctc cgtcaccatg ttaccagtaa agacataccc
    49081 taaataatca ggtatcagta acaatttatg tgcttttgcc aaattttctt tttcttcagc
    49141 aaacaattgg aacaaggtat tgaaaggctg gatctgaatc cctgtctgct catacaactt
    49201 atctagagaa tagatttcag aaaactgttc tactgctcca ttggtacgct tgtcccgata
    49261 agcaatcgga tcatttatcc gatccccttg ttcatcaatc agacagtaat cgactgccca
    49321 tgtatcgatc cccgcaaaaa ggcgatcaat ccctgtctgc tttaattttt caaatccaat
    49381 caaaatctct ttgataagat aatcgatctt ccagcgatcg tgaccgtctt tgttccgaaa
    49441 gccgtttttg aaccggtgta cttcttccaa gatcaaagaa ccttttgcat ccctcgtact
    49501 tttcattagt cgtccgcttg atgcaccgat atcgatggca acaaatgttg gattcatttc
    49561 tccacctctt ttactttatt gttgattagc actttattaa taaagcgtta tcatttattg
    49621 acaatgctat cataatacag aatcttatat tttgcttcac actattttgg tatataattg
    49681 cattatcttg acaagttggg agtgtttaca tggattactg ggaaaaagcc aaccactcat
    49741 ggtcggaaga ctcaaaaaga gtgatcttga cgcctacaca aagaagcagg aatttatttt
    49801 tttatatcca agaaatcggt tacttcaaag caccaatccc ttactatact gaacgagcac
    49861 atttaccttc ttacttgata aagtttactt tgtctggcaa aggttcgctt acatataatg
    49921 ataatcagca acagctaaaa gctggagact tattttttat tgactgccaa gaatatcagc
    49981 gttatcaaac gatcagcgaa gaaccatggg aaatggattg gatccatttg aatggtcaga
    50041 acgtccaatc attttatcag gagttcacaa aagacggcca taacaccttc cattcaacag
    50101 gagatccatc agaaaacaag atccaccatt tgatcacaga attgatccac atgcaacaag
    50161 gcacgaatgc ccgtaccgat ttccagtcct ctgtagctat ccacgagttg ctgaatgaac
    50221 tgattttgca aaagtatcag ctagatttcg aagaagagga tattcccgcc tacgtttaca
    50281 aactgaagca atacttagac gaacatttca aagaaacgat tacacttgat caattagaac
    50341 aacaattctt attgaataaa tatcagctga gcaaagattt ttccaaattt atcggttctc
    50401 caccaatcga ttatttgatc agcaaaaaac tttcttacgc taaagacctt cttcggtata
    50461 cagaatttac ggttcgaatg atttccgaag aaatagggat tgagaatttt gcttacttta
    50521 gccgcctgtt caaagcaaaa acaggactat cgccgagaga ctttcgtaaa ttcagctgat
    50581 tcatataata tgtacgtcat tttttcaaaa tattttgaaa tatatagata aaaataaaat
    50641 aaccgcagtt tctgcttcta tgtaaacaac agcagctact gcggttattt tttagtgatc
    50701 attctcattg ttcatcttca aaatgttcat aatgaaccaa ctgtttctgt gtatcacgtt
    50761 tcaaaaattc tttaggcgtt atgccgaact ctctcttgaa tgctttcaga aaatgcggat
    50821 aagaagaaaa accactttta ctatatacag cactagagct gcggtattct cgcaacaagt
    50881 gcttggcata gatcagcttt ttcttcatta catactgatg aaacgtaaat ccagtgtact
    50941 ttttaaattc tcgtgtgata tggtatttgc tgacaaaaaa ctgcttttcc atttcctcta
    51001 aagaaagcgg atgagataaa ttttttgaga tatattgtaa catttgttcc acacgctcat
    51061 taggaactac agcattctgt tcttgcgcac tctcttcttt ttgtacaact tgattgagaa
    51121 aaatcaagta ttctaccaga gcttgttcat attttatgtc ttcaccgtaa atttttttat
    51181 caggaggatg gtcgataaat gataattttt gcttcaatac ttcctgttct atttgcaata
    51241 cacgactcct cttctctccc attggttgaa aacaagccga tagattagac catggcgtgg
    51301 aacgactttc tagaaaagaa ggggtgacaa agatatagac acgctcgaat acatctgaag
    51361 attggcggac gatacgatgc aaatcattgg aatggatgag cagcacactt cctgctttga
    51421 tcgtaaattg tcgtccgttc aaataaaaag tcgcttctcc ctttaatgta gcatggatct
    51481 catagaaatc atgatgatga tagatcgttt tattttggct gacgacatct ttgacatgat
    51541 agatttcata ctgatcagaa accatcgtat tgacttgttc accgctgatt ttcttttgga
    51601 gcatgtgccg cacctccttt tgttcactta tgcacaattt tattatacca cgttttttgt
    51661 aatcaaaaag agctgctttt atatactctt ataaaaaaga agagacgtgg catcttctag
    51721 ccccgccccc tccattctaa atattagtta accaacgtct tctttacatt attcaagaag
    51781 acttcttcca taacgaatcc catcatcttt tgtttcttca agaaccacat acaggtacgg
    51841 acgattcttc atgatgattt ctttgatttt tgtgtactcg atcacaccgt ctcccaaatt
    51901 taccggcacg attttttcct gttcgacacg aaaatctttc aaatgaaccg cacatatctt
    51961 ttcaccaaaa cgttcaaaag cttcttctac caattggact tgttcttgat aatcactact
    52021 tgtgatcaaa ttggtcggat ctaaaatgat tcctagatag tccgaatcta ctgcttggat
    52081 cagctgctct acccttgcta aagaatacac cggatgattc aaacctggtt ctatccccac
    52141 catcatttgg tatttttctc cagcttttac caagcgacgg ataacggaca cagcttcagc
    52201 aaatgcttca tctgtgaaat tttcttccgt atattggatt tccggcaaaa cacatccagt
    52261 ttccgaagca accatcgacg caccaaagga agaagcatag cgaagatact gctcgaactt
    52321 tgtcagcaac tcttgtcgta tcgttaaatc tggatgaatc atattgatat agcaacttaa
    52381 aattcctacg gtcacttctt gcttttctaa aactcgtttg acataatttc ccatcccaga
    52441 attgatctca tttgcgccag aaggtatttc aggaaacgaa agacctaagg cgagctgcag
    52501 tgtatgaatc ccttgttctt ttgttttttc tgcaagatct tctatcgttt ggacttcgga
    52561 aagatcatgt cctctaattg taatgttcaa cataactatt ctcctaactc agcatattgg
    52621 gtagccacat gacgatttgc gggaagtaag taatcaaaaa caagacgact aagataaccc
    52681 cataaaaagg aagaagcggt ttcagcattg cctctgcttt tacgcctcct acacttgcac
    52741 cgacatatag tcctgtacct actggcggcg tgatggagcc tacacacaga ttcatgattg
    52801 aaaacaaccc gtaatgtaca ggatcaaccc ctacacttgt gacgattggt aaaaatattg
    52861 gtgtaaaaat caagatagca ggcgccacat ccataaacat acccaccagt aataacacaa
    52921 gattgactaa taacagaata ataaatttat tatccgttac gcccataatc aacgaactaa
    52981 ttgcctgagg aataccggta aacgccatgg cgaaagacat catggaagaa gtagccaata
    53041 agaacatgat cgtccctgac attgctactg attgaaacaa catattaggt atatctttta
    53101 gttttaccgt tttatagtaa aacatagcaa tcaacaggga gtaaatgaca gctatcgctg
    53161 aagcttctac tgctgtaaat atccccgtca agataccacc gataatgatg acaatcaata
    53221 gaaggctagg aatcgcctct tttattattt ttccagcatg agccatctgt cctttttcga
    53281 caacagggta tttattcttt ttagcaacga tgaatgctac tagcatgatt cctagcgccc
    53341 acaaagcgcc tacgagataa cctcccataa acaaagcaga gatcgaagca ccaccagcaa
    53401 caagtgaata catgataaaa gcagtacttg gaggaatgac catacctgtc ggagctgacg
    53461 cgatattgac cgctgtcgca aacttccggt catatccttc ttccacttgc tgagggatca
    53521 acactccgcc aatcgcggta gaagcggcaa tggccgagct agagatggaa ccaaataaag
    53581 cattccctaa cacattcgta tgagccaaag cccccggcac gcgcccgacg aacaacatcg
    53641 caaaatccac tagtttctta gctatccctc cattattcat gataatgccc gagagaacga
    53701 aaaacggaat agcgatcagc gaaaaactat tgatacttcc caccattttt tgagctgaac
    53761 taaaagcaga aacatcaaac ggtataacta acaataaagt catcatcgat gagaatgcaa
    53821 tacttatagc aatcggcatc cctaatacaa gcaacacaac aaatacaaaa aataacacta
    53881 atccggcttc tattgccatt ttattcctcc atttttatat tttttcttga attgctggct
    53941 tgttgcttaa tgtatcgatt agattgatca ggctatagat aatgatgagt acccccgata
    54001 caggtactga cagataaaca tatcccatag gaatacttaa agaaggcgag atctgcccca
    54061 ttgtcaatgt gacagcattc catccgccat acaccatgat catcgcagca aataccagaa
    54121 ataaactttg aacaacaact tctaaaattt tacttttttt gccagttaat ttttcactta
    54181 aaaccgttac ggctaaatgt gctttttgtc ccacaacata cgcggaagac aacatggcaa
    54241 accagacaag accgaatcga acaagctctt ccgtgaccgt atttggattt cctaaaaccg
    54301 ttctggaaaa tacttgccat aaaacaacag cgaccatccc aacaagcaaa acagctccca
    54361 ggatctctaa taccttgttt aaaatcattt tcatcacagc tacgctcctt gctcttggat
    54421 cttttgataa aggtctttgt aggtaggatc gtttttgaat atatcatgaa gtggggcaac
    54481 tgcctctcga aacggtgtat tatctacatc attgaattgg actccatgtt cttcttgtgc
    54541 taaagctttt tcttcttcaa ttgcttttgc aaaagcttca atttcaaaaa ccgttgattc
    54601 tttcgctgct tcttcaatgg ctttttcctg ctcatcagtt agctgttctt tgatggcatc
    54661 attcatgatg atgatatctg gcacacgtgt atgctcatca taggaatagt atttagccac
    54721 accaccatgt ccagctgtat acaagacaaa ttcattgttt tctgatccgt tgatcaaatt
    54781 ggattgaaga gacgtgtaca cttcatcact tcccataggt acgggcgaac cgcctaaaag
    54841 ctctaccatt ttgatagcgg tttcgctttg catcacacgg atcttctttc ccttcaaatc
    54901 ttccggcgta tggatcggac cgtctaccat ataaaagctg cgctgaccag aatcataata
    54961 ggtcaatccg gtaaatccta aatttttggt cgattggtag attggctcca ttatttcttc
    55021 attatccatc accttaaaga aatgttcttc atcattgaat agataaggaa ctgaaaaaat
    55081 cgaataatct ttagagaaac tttccaacgc tgaggcactt acttttgtga aatctactgc
    55141 tcctgactgt gtcaattcga tcagttcacg ttctccaccc agttgtccat ctgggaaata
    55201 ctggatctgt acggaaccat ctgttttttc ttttactaaa cgcccaaatt cattcattgc
    55261 atcaattact ggctggctgt tgcttgcata agcaaagcgc aaggtaacta tctcatttac
    55321 atctgcatct gcgacagttg ccacactaga attatttccg cagccgctta gacctagcag
    55381 acctaggcta agcgaacttg ctgcaaacag cagtgatgtt tttttcatat gggtttcctt
    55441 tcttttaaca ataagagacg agcaattctg tcaaacaaag caccgttaac gactgtccat
    55501 aaggcattgc tgtgattccg atattccgat aaaaatctaa actgtccccc attcctgtcc
    55561 cgattgaaac gttttgaact tctccttttt catcgatttg ttcaagcaat ccttggatag
    55621 cacgataagc gacttcttta tattcttgtg gtaaataacg tttatggacc gctttcaaaa
    55681 taccgtaagc aaatcctgca gttgcagaag attctacgta agaagaagga tcatccaaca
    55741 acgtatgcca taaaccgctt tcagactgat aagtttttaa tgcacgcact tgtgcttcaa
    55801 gtgtttcgat caataatttg cgcaatgcat cttctttcga taattctaag atttcaatga
    55861 tctctggaat agcaatcgtc aaccagcagt ttccacgagc ccaaaatgct tcggcatagt
    55921 tatgatttcc ttcaaacgtc cagccgtgat accacaatcc tgttcgttta tccatcaagt
    55981 atttgatatg gatcataaac tggtaacgag cttcttctaa atattctggg cgattcaaca
    56041 gtttcccgat ttttgccaaa ggaagcactg tcatcatcaa tgtatcgtcc cacaactgat
    56101 tcttattttc cggtccatat gtggcatgct gtaacccgtc ttcatttgtc cgaggcatgt
    56161 cattcatgac ccattctgcc cattgttcta aataaggcaa atagcgtgaa tctttcgtgt
    56221 cttcatacaa gtaagccata gtcaatagcg gtgccattgt attgacgttt ttgggcggag
    56281 cgccttcttc catacgatcc tcaaaccatt cattgaccac ttgataagcg cgaggatttt
    56341 ttgtcatctg gtaattttta taaataccat atagaccgac accttgtggc caattccaca
    56401 ctgtccagct tttgtcatct actttcagtc catcaaagtc caacaaaaat tcaccattat
    56461 cgtctttgat cgttgtcagg ttttcaacga gcaggtcaat tttttctttc actaattctt
    56521 taggtacaaa aatctcttct ttaataatca tctttacgcc acctttttaa acgctttcat
    56581 tttatatcct taatatagca gtaataccgt ccactataaa tatcgctttt tgaacaaaaa
    56641 ctgtctaaaa ttgacctaaa tgttaaataa caaaagtaac tttcagttac ttggaaatta
    56701 aaaaaagaac ttggagaaac aacgttttcc aagttctttt tcatctattt tcttatcttt
    56761 tttctacgct ttcttttgct tatccgttgt aagcatcaat gatgatctgt ttcaattcag
    56821 agatcaatgg ttctttcgga ttagctgtcg tacattggtc ttcgtaagct aattcagcca
    56881 tacggtctac ggttgtatct agtgtttctt gtgtgactcc ttgagctttt agactcatgt
    56941 tgatgccgac agattttcct aattcataaa cagccgttgc taaagcttcg actaattcct
    57001 ctgttgtttc gcctttcaga cctaagaatt ttgcgatatc tgcgtaatct gtatctgcac
    57061 ggaaatagtc atatttaggg aacatcgcat gtttttgtgg atcttttgca ttatagcgga
    57121 taatatgcgg taaaagaatc gcatttgtcc gtccatgagg gatcccgtat tccccgccga
    57181 ttttatgtgc gactgagtga caaataccta ggaatgcgtt agcaaacgcc ataccagcca
    57241 ttgtagaagc gttgtgcatt ttttcacgtg attccatatc aggtgttttt actgattttt
    57301 ctaaatagtc aaagactaac ttgattgctt gtaggctcaa tccacgtgta taatctgaag
    57361 ccatgactga aacataggat tcgattgcat gtgttaacac atccatcccg gtatctgctg
    57421 tgacagatgc tggaactgac atgacgaatt gaggatcgac gattgcgaca tctggcgtca
    57481 atgcataatc tgctaacgga tatttcacat gtgtttcact gtcagtgatg accgcaaatg
    57541 gcgttacttc agaaccagtc cctgatgttg tcgggataca tacgaattgt gttttttctg
    57601 gtttgtcgat cttatatgtc cgtttacgga tatccaagaa tttttgtttt gcaccaaaga
    57661 aagatgtgtc tgggtgttca tagaacatcc acattccctt agctgcgtcc attgcagaac
    57721 cgcctccaag agcgattact gtatctggct tgaagtctgc catcagtttc gttcctgcgt
    57781 atacggtatt tgtcgatggg ttcggttcaa catctgagaa gacttcgatc ttcacatcat
    57841 ttttacgtcg tgccaatact tcacgaactg tatcgcagta accgaattgg accataccag
    57901 ggtcacaaac gatcatgaca cgttcaacgt tttccatttt ctctaagtac aatagagagt
    57961 tcttttcaaa gaagattttt ggcggtaatt tgaaccattg catgttattt ctccgtttcg
    58021 ctacagtttt gacattgatt aagtttacag cagagacgtt acgagaaaca gagttcttac
    58081 cataagaacc gcatcccaaa gtcaatgacg gaatcatttc gttatagata tcaccgatgc
    58141 cgccttctgc agatggtgta ttcactaaaa tacgacaagc tttcattcga agaccgaatt
    58201 tgacatgcaa ctcttcgttt tctgaatgga taactgctgt atgtcctaat cctccaagat
    58261 tcaacatacc ttcacacaaa tcaaacgcat ggtccgtgtt gttagctttg atcatggcaa
    58321 gaactggaga aagtttttct cttgatagcg gataatctgg gcctacgcct tccaattcag
    58381 caatcagcat tttcgttcct tttggtacac tgattcctgc caattttgcg atttccatcg
    58441 cagaatgtcc aacgattgat ggattgaccg catattttcc ttcgttcatc actgcatctt
    58501 ctaatttttg caattcatct ggttttacga tataaacttg gtgtgcttgg aattctgctt
    58561 ttactgctgc atagatttct ttatccacga tcacagcttg ttcagaagca caaatcattc
    58621 cattatcaaa tgttttcgaa acgatcaaat cgttcactgc acgtttaatt tttgctgttt
    58681 tttcaatata agctggtacg ttacctggac ctacacctaa agctggtttt cctgtagagt
    58741 aagcagactt gaccattcca gctccacctg tcgctaagac gatcgcgata cctggatggt
    58801 tcattagcat agaagtcgct tcgatcgaag gatgttcgat ccattggata caattttcag
    58861 gagctccggc agcgatagca gcatcacgta ccactcgtgc tgcttctgca gaagattttt
    58921 gggcacttgg atggaaagca aaaacgattg gatttcttgt tttcaacgcg atcattgatt
    58981 tgaaaatcgt tgtggaagtc ggattcgttg ttggagttac tccgcaaacc acaccgactg
    59041 gttcagcaat ttcaatcaac cctttttgga catcttcatt gatcacacca actgttttat
    59101 catgtttgat attatgccaa atatattcgg acgcatacat atttttgatt gctttatctt
    59161 cgtaaacacc gcggcctgtt tcctctacag ccatcttcgc taatggcata tgttgatcca
    59221 aagctgccat tgccatttca tgcacgatat ggtctacttt ttcttgatca aagctttcca
    59281 tttctttcaa tgctgcattt gctttttctg ccaaatcatc aatcattgct tgtacgtcaa
    59341 ttgtcttcgt tttttctttt tctattactt tagccatcat tatcctccta atgggtcatg
    59401 gttatttgtt aaataattca catgtatatc atacaatatt tatttttcta tgtaaacact
    59461 tttttgtgat ttttttcaca gttattttta aatataaaat tgctttattt acaggtgttt
    59521 gtatagaaaa atatataaag ttatttatta ttatttatat gacacacccg attattcaat
    59581 attgagcaat atatcccatg ctcttatctc tttctttttt gaataaaaaa tgaggtagga
    59641 catctttctg ccctacctcg tctttaaata agctttgata cttatttttc ttccttctct
    59701 tctgtctctt ccagcgtttc tgttgtttca gtttttactt caactgtctc agctggttct
    59761 tctgttgttt caacagtagt cgttgcatca tttgttacga cagtccctgg tttgaccgtt
    59821 ttgattgctg cacgatcgta ctcaaggaag atcccttcgc agtctaaaac aactgtccgt
    59881 ttgtcattgt cgatttctga aacaactcca tgtaatccgc cgatcgttac gactgaatca
    59941 cctggtttca tgctatctaa caagttttga cgttcttgct gttgtttctt ttgcgaacgt
    60001 gacataaaaa accacattgc taatagcgcg ataaacatca caagcattgg taatgttccc
    60061 atttttttca cctcactaat tctgtatcta caaaaaacac tttagcagaa aaatgctgat
    60121 aacactagtt ttttacttaa tttttaaaag attttccttt agaagctttt tgcgttttct
    60181 ttattgaacc cgtattcttc aaaaaaggct tctctaaatt caagcaaatt atcatccatg
    60241 attgcttgac gtacttgttt cattagattc aacaagaagt ataaattgtg gtaagaagtc
    60301 aaacgaatcc caaatgtttc atcacatttg atcaaatggc ggatataggc acgtgtatag
    60361 tttttacatg tataacaatc acatttctca tcaattggac ggaaatcatg ggcatatttc
    60421 gcatttttca ctactagacg gccttgagaa gtcatacatg tgccatttcg agcgattcga
    60481 gtaggcaaga cacagtcaaa catgtctact ccacggataa caccatcgat caatgaatca
    60541 gcagcaccga cacccatcaa gtaacgtggt ttgttttcgg ggatcaacgg tgtagtgaat
    60601 tctaatacac gattcatttc tgatttaggt tccccgacag ataacccgcc gattgagtaa
    60661 ccagggaaat ccatcccgac tagatctttc gcgctttgac gacgaagatc ttcaaaccct
    60721 gctccttgga tgattccaaa taatccttga cggtctggat tagcatgagc tttcaatcct
    60781 cgttctgccc atcgagacgt acgttctact gattttttca cgtagtcgta actttcatcg
    60841 aatggtggac attcgtcaaa actcatcatg atatcagagc ccaatttatt ttggatgttg
    60901 attgcttttt ctggtgataa aaacatacgc gaaccgttca agtgattttt gaaatgcacg
    60961 ccttcttctt cgatattccg catatcactt aatgaaaaaa cttgaaagcc gcctgaatct
    61021 gttaaaatcg gttgatccca gttcataaat ttatgcagtc cgccagcttc ttctactaag
    61081 tcttcaccag ggcgtagcca taaatgatat gtattactta aaataacgcc agcacccatt
    61141 tctttcaact cttctgggga cattgttttt actgtagcta atgttcctac tggcatgaac
    61201 attggtgtgg ggaaagttcc gtgtggcgtg atcaattccc ctaaacgcgc gccagtatgt
    61261 ttttctttct tgattaaacg atagcgaatg gcaggttgcg tcattcattt ccctactttc
    61321 tatataaaat atcttgacaa ctcccaccat cataatcgtt tcaagtgctt tttgcaagtt
    61381 ccctcggctt ccttctactt tatttaatat tctttttttt atcctttttt tatgaataac
    61441 aaaaaaaaga aaaacattat gacagaaata ttttttgata catggtatat tggtgttatt
    61501 aaagaaaagg agggaaaaat catgcaatct tctgcagaat taaaacgcca agcaaaagag
    61561 agtctaaaag gacgttgggg acaagctgtt ttactaaatc taatccctac attgattggt
    61621 attgctacta ttcttcttat tatgattcct attatcttgt ttgccaccac catatatgat
    61681 ggatcagcga gcgtctcaga agcgacaact tcaggaggcg gtagttcagg aggcggtggc
    61741 ggaattattt ccagcatcat tagcgctttg ttcatgagcg gtatttcttg gacttatctt
    61801 gatattttac gtggacaaaa agatcagatc gaaccattca aagatgcatt tcgtggattc
    61861 aaaggtttgt ttatcggcgg agtgatcagc ttagctgtgc tgatctcgat ctttacaaca
    61921 ttatggggtt tgctattagt tattcctgga atcattaaaa gctattctta ttctcaaagc
    61981 tattttattt actacgatat cgtccaagaa acaggacaaa cacctaaagt actggatacg
    62041 atcactgcaa gtcgaaaatt gatggatggt tataaaggac aacttttctg gttagatctt
    62101 tcatttatcg gctggcatat cttagcatta gcaactgctg gtattggtta tctatggctc
    62161 agcccataca tttctgcaac aaaagcagca ttttatgaac aattgccaaa agatatttaa
    62221 aagagagtgt gacttgtgac cgagggggtg gcaggagaac accgtttatc gagaggcagt
    62281 aaaagaaaca ttcagcccat tagcaaaaag gaggtgtgac aacattcatg tcacacctcc
    62341 tttttgtata gttccagtaa aaagaaaatc aacttagaaa cagttaatca ttcctcttct
    62401 tctgcttccg gtaatcgatg gaacttgatc agttcattca ccgcgattgg tacgatagat
    62461 aaaatccctt ccaagaacca gtgattcaaa ctgatgtgta ctaggccgaa tagttcttgc
    62521 gtaaatggca gcaaagcaac agccgttgta atagctaatg ccagtaacgc catttctacc
    62581 aaagctttat tggtcgctaa attgactttg aagatcgatt ggctgctgcg tacattgaac
    62641 acatgcagaa tcgatgaata agctaagatc aagaatgcaa cagtttgacc gacatgctga
    62701 cttgcgtcta cccatgggct gatagtatcg acataactac ctaaataata accaaacaag
    62761 gttacgatgg tgaagacccc tgcatttatg gcaatttttt gcaataaacc tcgagcaaag
    62821 atcccttcat ttttcggaat gggtggctga tccatgatgc cgtgttccgc tggctctctt
    62881 cctaaagcaa atcctggaag tccatcagca actacattga caaacagtag ttgcacagct
    62941 gtaaatggtg ctccccatcc taacagcatc gcaatcaaaa caataaagat ctccgaaata
    63001 ttacagctta gcaaaaagtt gatagcttta cgaatattct gataaaccga acgtccttga
    63061 ctgacagcgt ctacgatcgt cgcaaagttg tcatccgtca aaatcatatc tgcggcactt
    63121 tgcgccacat ctgttcctgt gatccccatg gcacacccaa cgttacttgc tttcaacgct
    63181 ggtgcatcat tcacaccatc cccagtcatc gctacgactg cacccgtacg ttgccaagat
    63241 ttgacgatcc ggatcttgtc ttctggcgtt acccgagcat agacagagag agctttgaca
    63301 cgcgcatcta attcttcgtc tgataattga tgcagttctg atcctgaaag tgcttctgac
    63361 ggatcattca agatacctaa ttctttcgct atggcactgg cagtcaccac atgatctcca
    63421 gtgatcatga ctgttttgat gccagccttt ttcgctcgct tgattgctcc tttactttct
    63481 ggacgtggtg gatcgatcat tccgatcaga ccaatcaaac gtaagtcttt ttccagtgct
    63541 tcagaagaaa tatcttgcgg ttcttcgtca taagtagcat aaccaacagc aatcactctc
    63601 agtgcccgtt taccaaagcg atcattaacg atcgccgctt gttctacatc gcctgaacta
    63661 aagcgcggag caagaacatc gaatgctcct ttggtgattg agatgtattt ttcgcccatt
    63721 tggtgaactg ttgtcatcat ttttcgttca gaatcaaaag gaagctcgtt tactcgtgga
    63781 tatttttctt ctaattctgc ctttgtatga taattctctt caacagccct tacgatggct
    63841 acttctgttg gattaccttt gataacaagg tcgtcatctt cttgctcgac cgtcacatct
    63901 gtacatagtg cagccatttt caatatttcc atcgcgctgt tcgtcattga atcttcgata
    63961 ttcgttactt catcttcttt gctccatacc cggcggacgc gcatttcatt ttgtgtcagc
    64021 gttcctgttt tgtctgagca gataacatta gcggttccta gcgtttcaac tgctggcaac
    64081 tgtcggatga tcgcatgttt cctcgccatc ttctgcacac cgtatgcaag tgtcaacgta
    64141 acaataacag tcaaggtttc cggtacagct gcaacagcca aggaaatcga agtcatgaac
    64201 atctcaagga gtggttctcc ttgcagttca ccaatcacaa atactaaagc cgcagccgct
    64261 aaagcgatca tactgattcg tttgcctagc tgattcaatc ggacctgtaa aggtgttttt
    64321 tgcatagtat tttcgttcaa aagatccgcg atcttaccca tttctgtagc catgccaatg
    64381 gcagtgacga tcgctttccc acgacctgca gcaaccgtac atcctttaaa taccatatta
    64441 agttggtcac ctaatgactc atcttcttca gcaataaatg ctgcatcttt ttcaactgct
    64501 tcactttctc cagtcaacgc cgattcttct acacgtaatt gtgatgcttc gatcaaacgg
    64561 gcatcggcag aaatagcatc accggactct aaaacaagaa tatcacccac taccagttgc
    64621 tctgactcaa cagtggtcac tttgccgtct cgtatgacag ttgccgtttg tttattcata
    64681 tcttgcaagg attccagtgc tttttctgcg tttccttctt ggacaatcgc caataccgag
    64741 ttgatcacaa cgatagcgat gatcagcagt ccttcaaata aatccccatg ttctgtagca
    64801 aatgcggtat aaaaggaaat caccgctgct acaagaagga tgatcgttgt aaaatcggac
    64861 aagcttcgaa agaatttttt gatcatcgat tctttcggcg cctcatcgaa tttattcaat
    64921 ccctgctttt ttcgccgttc atccacttct tgtgaagaca acccagtatc tggatctgct
    64981 tctgttacct tctttacttc ttctattgtc tgcttgtatt cttccatcct attcctcctt
    65041 taaaatcttc gtacaaaaaa aggtacttat tttactataa catccttttt ttatttactt
    65101 caaataaagg gcttatcgat tatttgttaa gaaagcgtaa aatttaaagt gcttatattt
    65161 gcaaacgcta ccaaaggatg ctattatata gatgtaagga aggaggatac catcaaatag
    65221 acagaagaat ttctcgatag aacagtgtaa gcaaacaaag ttgttagaag tacaggtttc
    65281 acccagacat gcgtgtagag tacaaaccta taaatagtga atgcgtatgg atgtttggat
    65341 cacgaagtat ccgaaacaag aagtaatgcg atacgtaaca attgaataac gtaaacgtct
    65401 gaaaattgaa taggaacaag agatgtttca aatgttgaag atgtaacgaa aacaaaattt
    65461 ttgtttaaca tgaagaaatt caacaccgtg ctttgcatgt atgatggaaa gttacaatca
    65521 tttctgttta tttgaatcct tccgaggtac aagaaagccg agcttatcga gagctcggct
    65581 ttttctttgt cataaaatct ttgtaaagct tttttgttat tcaaaactag cggcttttca
    65641 taaccttatt tcacgaacat cgcatctcca aaactaaaga aacgatagcg ctcttcaatc
    65701 gcatgctggt aagcagataa agtcaattct cttcctgcaa aggcactaac taacatgact
    65761 aaagtcgatt ttggcaaatg gaaattagtt gagaaagctt ctaccacttt gaattcatag
    65821 ccaggcgtaa tgaaaatatc agtccatccg ctgtctgctt tgatttctcc attaaatttc
    65881 gttccaatcg tttctaatgt tcgaattgaa gttgttccga cagccacgat tttcccgcca
    65941 tttttacgta cttggttcaa tcgctcagcc gcttcttccg tcaaacggta gaattcacta
    66001 tgcatatggt gttcttcaat tttatctacg ctgacaggtc ggaatgtacc taaccctaca
    66061 tgtagtgtca gatagactaa ttcaacaccc tttgcttcga tctcatcaag taattctttc
    66121 gtaaaatgca atccagctgt tggcgctgca gcagaaccat tttctttcgc atagacagtt
    66181 tgatagcgat ctgggtcttc cagacgttct ttgatatatg gaggcaatgg catttctccc
    66241 aatgattcaa gaatctctag aaaaattcct tcatactcaa agtcaatgat ccgtccgccg
    66301 tgttccaatt cttctttcac tactgcttgc aatctgccat caccaaaaga gattcttgtc
    66361 ccaactttgg cacgtttcgc aggtttgatc aatgtctccc acgtatctcc ttgtgtattc
    66421 gttagaagaa ggacttctaa atgcgcacca gtatctggtt tttctccata taaacgagca
    66481 ggcagaactc gtgtattatt cataactagc gcatcaccag gctgtaactc ttcaatgatt
    66541 tcatggaaat gtttatcttc catctctcca gttttccgat ccaaaacaag taaacgagaa
    66601 tgatcgcggt cttttaatgg tgtttgtgcg attaattctt ccggcaagtc aaaatcaaaa
    66661 tcttctgttg ttaacatatc gtcactcact ttctatcatg tgcttcatca ttctatcatg
    66721 tttttcgttc tgttggcaaa atcagcactt tttcacttct attttttgtt ttcctaaata
    66781 aaaaaactac cctatttgta ttttttcatt gttttaggca tactagtaat agatagttct
    66841 tcattgaaaa tagaaaaaga ggtggcacca tgattgaatt tcaaaatgtg tcaaaaattt
    66901 ataaaggtgg aaaagtcgct gtagaggacg tcaatctttc atttgaaaag ggtgagttca
    66961 tttgttttat cggtacgagc ggaagcggaa aaacgacgac gatgcggatg atcaaccgaa
    67021 tgactgatcc aacacaaggg aaaattttga ttgatggaaa atccatccaa gaaattgatc
    67081 cagtggaatt gcgacgtcag atcggctatg ttatccaaag tattggattg atgcctcaca
    67141 tgacgatccg tgaaaatatc actcttgtcc aaaaattgtt gaaagtcagt caagaagaac
    67201 ggaataaaac agctgaaaaa atgattgatc ttgtggaatt gccccgtgag atgttagatc
    67261 gctacccaca tgaattatct ggtggtcagc agcagcgtat tggagtcgtt cgtgcccttg
    67321 cagcgaatca agatatcatc ttgatggacg agccattcgg tgcgcttgat ccaatcactc
    67381 gtgattcctt gcaagacctt gtcaaagatt tacaagagcg tttgggaaaa acgatcgtat
    67441 ttgtaaccca tgacatggat gaagcgatta aactagcaag ccgtatcgcc atcatgagtg
    67501 aaggccgtgt gatccaattt gatacaccag aaaatatttt acgtcatcct gcaaacgatt
    67561 tcgtagaaga gttgattgga gaagatcgcc tactacaagc caagccaaat gcgacaagag
    67621 tcggcgaagt tatgctaaat acagcaatca cgattacacc ggaaaaatca ttacaagaag
    67681 caatcaaact gatgagggaa aaacgtgtag atacgttgtt agttaccgat aattcgaatg
    67741 tattaaaagg atttatcgat gtagaaacgt tgaataaaaa acgaggaaaa gtatccagtg
    67801 tcggcgacat tttgaataaa catgtttttt acgtaaaaga atccgcctat cttcgtgata
    67861 ccttgcaacg cattttaaaa cgcgggctga aatacgtgcc ggtcgttgat gaacagaaca
    67921 aagtcgtagg tatcctgact cgtgcatcat tagtggatat cgtctacgat gtgatttggg
    67981 gagaagatcc cgcaactact gatgttgcag agtcagctac tcctgaagaa tctaaggagg
    68041 tctgacctat gcagcagttt tttcatcagc acggttcaga aattctctca aaaggttttg
    68101 aacatcttta tatttcagga cttgctttga tcattggtat catcattgct gtaccgcttg
    68161 gtgtcttact gacacgtttt ccaaaagctg ccacgattgt gattggctta accagtgcct
    68221 tgcagacaat cccttctctt gctttattgg cattgatgat cccgctattt ggcgtaggta
    68281 aattacctgc gattatcgca ctctttattt attcattatt gccgatttta cgtaatacgt
    68341 acattgggat gaaaaatgtc gattggaatt atcgggatgt ggcaaaaggc atggggatga
    68401 ctgagttcca atccattttt tccgttgaat tgcccattgc tatgccaacg atcatggctg
    68461 gtattcgttt agctgccgtt tacgtgattg catgggctac acttgcctct tatatcggcg
    68521 ctggtggttt aggcgatttg atttttagtg gactgaataa ttaccaacca gatctcattt
    68581 tggcaggtac gatccctgta acaattttag cactattggc tgattggctt ctaggtctct
    68641 tggaacaccg gctgacaccg atcgcactta gagaggagaa tgaagaatga aacgtatact
    68701 aaaaatgacc atggttcttt tctctcttct tatacttgcg agttgttcct tccctggtct
    68761 tgccagcaat acagatgaag acaccatttc gatcacaggt ggaatcactt cagaagcaca
    68821 gatcttagca agtctagttg ccggaatggt tgaacattat acagataaaa ataccgcaat
    68881 catcaacaat ctggctacta caactatcaa ccatcaagcg atgatgaacg gagatgcttc
    68941 aatttcagcg gctcgctaca caggaacaga tttaacgact acattgaacc ttcctcctga
    69001 aaaagatccg aaaaaagcgt ttgctaccgt gaaagatgaa tttgagaaaa gatacggtca
    69061 aacgtggttc ccgtcctata gttttgaaaa tacgtatgtc tttcttgttc gaaaagacac
    69121 cgcacaaaaa taccatctat ctaaagtcag cgatctgaaa aatgtagcgg atgaattagt
    69181 agctggtgta gatacttctt ggatcaatcg taaaggagac ggttatgacg gcttccaaga
    69241 aacttatggc ttctccttca attcgatatt acctatgcag attggacttg tttatgacgc
    69301 agtcgaagca ggaaaaatgg atattgttct tggctactct acggatggac ggatcgccag
    69361 ttatgatcta gtcatgttgg aagatgatcg tcaattcttc ccaccatatg atgctgctcc
    69421 agttgtagac aacaagatat tagctgatac gcctcattta aaagaagcct taaataagtt
    69481 aggtcatacc atcagtacgg aaaaaatgca ggaattgaac tacgaagcag ataataatct
    69541 agtggaacca tcagtagtag cacaacgttt cttacaagaa aaccactatt ttgaagggaa
    69601 gtgaagcaat tggataaaat gaatgtcttt caacaatttt tctattattt ccaggaaaat
    69661 ggctcctata tctttgcaca atttatccgt cacttcctga tttctatcta tggtgtcctc
    69721 tttgcagcag ttgtcgggat tccggttggg atcatgattt ctaggagacg taaattagca
    69781 aactgggtga ttcgtttggc gaatatcatc cagacgatcc cttctctagc catgatctcc
    69841 attttaatca ttggattagg cctgggagtc aatgtcgtga ttgttactgt atttttgtat
    69901 tccctcttac cgatcatcaa gaatacgtat accgggatga tccaagtaga caaaaacatc
    69961 cttgatgtcg gcaaaggcat ggggatgact gctagacaac gactattcat ggtagagtta
    70021 ccactctctg tttctgttat catggcaggc ataagaaacg cgttagttgt tgccatcggg
    70081 ataaccgcga tcggtgcatt cgtcggtgct ggtggtcttg gagatatcat tatccgagga
    70141 accaatgcaa cagagggcac atcgattatt ttagcaggtg cattgccaac tgcattaatg
    70201 gcgatcatca cggactggct tttaggtatt ttggaaagac ggctagatcc agccagccgt
    70261 acatcacgct gatgttattg taaaaaacaa aagcttctgc gaccatttgt tggtcgcaaa
    70321 ggctttttta gttctgtcat ttttaaggca ataatccact ctgattcttc cctccttatg
    70381 ggcaaagagt tgcttttctt agctatttat ccattccgta tactccaact tcatactgcc
    70441 aacgggttca tatctgcatc caccgactaa gtttttttct tatccgctaa ggcattttgc
    70501 caatccattt tcccatcact cgtcatggaa ttcataccac atgatctcta aatactcgtc
    70561 tgcttgttct ttgaattggg catcaattct tacatccttt ggcgtggctt tcatttaagc
    70621 cttttccatc agtcctcgat tgttcgatgc cttcagctgc atcatcaaaa ctggtgactg
    70681 ccgtatcggt aacttcgatc atcttttata caatcgggaa cttgccatcc tcatccttgg
    70741 ctaaaaacat atctagccat tccagcttct cgccatggga ggtttgcggt tcctaaaacc
    70801 ggtacacgat tcttatggac tgcatccgtc gcaactagac ttggcgatac gatgatcctt
    70861 caccagaaga gcacccccgt aaaccaattg atcgatatat tgccaataag aaaagacatt
    70921 ggcgtaaaag atatcgatcc ctcgtgatgc attgccgttg atactgctat tcatggccga
    70981 aagcgccacg actttaactt cttccgtttg agtgacattc atgttcggca atgtcgcttt
    71041 ggatacccgc tctgctaaag gaacgacact ggtattgtat ttcgtatctg tatcttttcc
    71101 aaaagaccat gccaacgaat cctctgggaa ccaataagac gactccggtt gattgtccat
    71161 tgcttttttc aacatacttt tggctgtttc tcgataaacg acatttccaa ttgtcttcgc
    71221 ctcactttgg cgataatcga tggtcgttgc cactgccaac actaacaacg atgctccaat
    71281 tttactgatt ttccttgtca cacttcttcc tccttgtttt acataaaccc gtcaacattc
    71341 cattcctaaa ctcaaacaat gacccttcaa aggtggagat ataggaacaa attaaagaaa
    71401 tcatgcaata aatccaagaa ggttggtttt agaacaaaaa aagagtctcc tttttgggga
    71461 gactctttgt taactatcta aaaaggttgg ctcttctcac ttcactcata atgtgtccag
    71521 gcagaataaa tttctacaac tttattttcc tcatcaactt tgtaaaccac tcgatgctgt
    71581 ctattcagcc tgcgtgagta tctgccttca tgtgtaggtc tcagcttttc aaaagactgc
    71641 gtgggcatat atggatcttc cttcaatgtc tgaatcactt cttcaaattg tttctttaaa
    71701 ttcgtttgct tgatttttct taaatccact ttcgcagagt ttttgattgc gactgtatag
    71761 ttactcatca aagagcttcc caatcaatat catcgatatt cgtaaagcta ctgtcgtctt
    71821 tttcgcggtc tcgtacttta tctaaagtac ctgtttgctc aagaaaaagg gtttcttgaa
    71881 tcgctctcca gtcttccagc ccaatcaata cagcattgtt tccactacga tcactaataa
    71941 tctcgatttc agtatgattt tcatttacct ctttcaataa ctgataaaaa tttttacgag
    72001 cagtgctagg attcatcgtt gtattagcca ttgtctctcc tcctttttct gatataatta
    72061 tagcgtactt gattaagtac gtcaaaaaaa tacaataaag cacttaaatt cagcaaactt
    72121 ttcctctttt ttacatagag aaaaagaccc ctttttaggg aggatctttg tccacgctca
    72181 cttcttactc ctttacgact agcggtagcc aaacgtaaag taattggtaa caacgtatca
    72241 tctttagcaa aggtcgaatc caaagcctgt gagtctatgc aacaacacca atacacgaag
    72301 gttcctcgtt gcagtgtgac ttgattgata tcttgaataa cctgaggata cgcacgaaag
    72361 atttgtaacg gttattcaaa actgattttg gccgtcaagt cttctactgc ctcaaaaatg
    72421 attgcctctt tcgtctcctg tcattcatgt tcactatcga tttgatactt gcttagaccg
    72481 ttgggtttgt gaatcaccaa ttaaaaatgg cactgagtta tggtaacaaa aaatggtcac
    72541 ttgacgaggc tgagattcct acttatgaag acacatggca cttaagagtc gaggtaaagg
    72601 aagaagctga aaatatagga ggctgtacat tatttggcaa aggattcgga aattatgatc
    72661 aagacatcaa aatcaaaatg ttttacagct aaataggaag aataataaca tttcatacgc
    72721 tgttcccatc tttaatggct tatagagggc acctttagct gagaataaga caaaacagac
    72781 cctctagctt caattaagag ctagagggtc tgtttttgat tttaaaactt ggtttatttc
    72841 ttcaaatggt agctataggt gctgacaacg atattttcac gccaagacaa tcgcaatctt
    72901 aaccgcaaac ttgtttggtt atggagaata ttctgccagc gtctgtttgg tacaaattga
    72961 ggaatcaaca cagtagttgt atagttttgt ttcgctgcat ttttacttac gatatctaca
    73021 taacggataa ttggattttc aatcgagcga taagaagagt ggacgattga aaaacggaca
    73081 tctgggaaat gctttttaaa ttctgcttcg atttcttttt ctttttcgac atcttcgtct
    73141 agcgaaacat gcatcgcaac gacataatca ccgatcgaac gtgcgtaatt caacgcaccg
    73201 atatttaccc gtgtcacatt cccgactaat acaagaacgg tattcccgtc ataatcatgt
    73261 agttttgcat cattttctaa acgaagctgt tctgctactt ttttataatg atcatggatc
    73321 ttataaaaaa tgaacataac gattggcata atgatgaaga aaggccaaat gtcccctaac
    73381 cgatagacaa acaaaatcgc aatgattgca tatgagatga acgcacccgt aatattggca
    73441 atcgatttgc ttaaccatct ttttccttct tttttccatt tgacgaccat ccctgtttga
    73501 gataaagcaa atggaatgaa cacgccgata gagtataacg gaatcaagcg ttctgttgag
    73561 ccatggaaaa taaacagcaa tacgatcgaa cctagcgcta gtgtgataat cccattggaa
    73621 tagcctagtc gatccccacg atcttgatac atgtgaggca tgaatttatc ttttgccaga
    73681 ttgtatgcaa gaactggaaa agcagaaaaa ccggtgttag cagcaactgc taaaatcagc
    73741 gctgtagcaa attgaaggac gtaatacaaa ataccatgtc caaagacagc tttaccaatt
    73801 tgagacaaaa cagtgacttc tttttcagga acgatcccat accaatagtt gataaatgtg
    73861 atccccacga agaagaaacc taagatcaat gccatcatcg tcaatgtagc agcggcattt
    73921 tttgctcttg gcttcttaaa gaatggtaca gcattactaa tcgcctccac cccagttaaa
    73981 gaggaagaac cagaagaaaa tgctcgtaaa atcaaagcga tagaaacacc cggcacagcc
    74041 gctcctggaa gtgcagtagc ttgcaatggc acagcacctg tcacgatatt atataaacca
    74101 acaacgatca gtaacgagat cacaaggata aatgtgtaca ccggaaataa taggaacgat
    74161 gcagattccc tcagcccacg aagattcagc atcatcagta gcaaaacgat tgtcacagaa
    74221 atagcgactt gatgaccgta gagtgctggc accgctgatg tgatcgcttc agcacctgct
    74281 gagacagata ctgctactgt caacatgtag tcgatcaata aagagccacc ggaaatcaag
    74341 ccagcattct ttccaagatt ctcactgctg acgacatatg ctcccccgcc atgaggataa
    74401 gcatggatga tttgacgata tgatagcgtt aatgaaatca ataaaataat aacaaaagcg
    74461 gcaatgggta gcgaatacca gatggctgca gcagacaaag cgactaaaac gacaacgatt
    74521 tgttccgtac catatgcaat agatgataac gcatcagacg acaataatgc caaagcagca
    74581 aatcgggtta atttgtgctc atcattttca gcagatttta aaggcttacc tactaacaac
    74641 ctttttaagt aatccaattt ctaaactcct ttacacacaa ttttacttca agttttatag
    74701 tcgaaaattt atagtaaaca agatgttata gtacgctcac tgaccttaaa agtcaataaa
    74761 ctttaagaaa ataattggaa aaaaacagaa aaatatcaag cgctttttca aacgctttaa
    74821 tacagcaaaa atctaacatt tttttatggg ctttttcttt gaattctata ataaaaggat
    74881 agaacttgac ttagaaaatc aagttctatc ctttttgata tcttaacttt tggaagagag
    74941 atgtaaggct gctttctacc catcattctt actactcgaa gcatagcgca gttgtcacaa
    75001 cctcttgata aacggtgttt aaaagcttgc atctgcggta ataagcccaa ccaaattaaa
    75061 aacataagaa gctgttttta tttggtcgtt cttattactt gatgcagagc agctttttta
    75121 caacctcttg gtacacggtg ttcaatcagc tgaccctcgg tattagctca aaaaaacggc
    75181 aaaatatgag gaactatttt tccatttttt tctctaatac tcaggtcaaa acactgattt
    75241 cacaacctct ttttttaatg aaaaatatgg ctctcatgcg ccgcttcttt gaatttcgtc
    75301 attttttctt cgatgaacgg atagattgcc gttcctacga ttccaaagac aacaaacaaa
    75361 ccgatcatga tccagattgc tttcgtagca tttggccaat aaattcctcc tgcagattcc
    75421 cgtaacaagt ttaccgcatg agtaaatggc aagaacggat tgatcatttg gaagaatttc
    75481 cctgagactt ggatcggata gttcccgcct ccgccagaga tcgacagtac taagatgata
    75541 atagcgatcc ctttaccgac attatcgaat aatgcagcca agacatagac gatcatcatg
    75601 aacgctaagg cgatcaagac agcaaatgac acgctgtaga ccggattttg gacatctact
    75661 cctagtaaga aaatattccc taatgtaacg atcaagcttt gcgcaatcgc cattgtcaaa
    75721 aatgtcagca tacgagcaac gaattgttct cgtttcgtaa aattgtttcg gtctttcttt
    75781 cctaaatagt attctgtcgt agcaacactt gaaagaagaa cagcgccgac ccacagacat
    75841 agtgcagtat aaaacggggt gctagctgaa ccgttatttg cgattggata aagcgcattg
    75901 gtttgtagct caacaggttg tgtaaagaag tcactttctt ttgttgcgtc tagtttcaat
    75961 aatttgatga cttcgcctag atcgacttct tgttcgcctt ttcggatcgc gtctgctgct
    76021 ttttggatac cagctttgat atttggccag tcattgttga tcaagtccgc agcagcgttc
    76081 acagctgttt cgacttctgg cattttttca tttactgttg tcaatgtacc ggtgatttca
    76141 ttttttagtg ctggccaatc attttggata aaatcagcgg ccaatcctaa tttttgctga
    76201 atgatcggta attcattgtt gtataggtct gccccttcat tgatgccatt gacgatggta
    76261 tccatatttc cattcagcat tgtattggca tcatggattt cttgtccaat tgcaggcatt
    76321 tctttttgat atttttctaa aattgccact gcattcgtta cagttgcttt cgttgagctg
    76381 agaagcgaat caaagtcgat ctggtccgct ttgctcagtg cgccttgtgc agtcccaatc
    76441 gtatcgatga cttggtctag tagagaagtg acagtggaac tgatttgacc tgtattgata
    76501 ccagcaatga tgccattgat attattaaca acggcatcaa tttgatctag caattcatca
    76561 atagccttcg tgtcttcatt ttgaacagct gtgttcaaag cagataggcg gttttgcaga
    76621 ttgcttagca agggttttaa ttgatttagc tgatcaataa ttggctgtaa tttcgtattt
    76681 ccagcacttg tttgcaattt agtcaggaac tcgaccagtt tatcgattgc attttgttgt
    76741 tgagatattc cgtcaataaa gccgttcaat acattgctga tgtttttctt ttcatcatca
    76801 gtcagcttac catcttcaat agctgttctt acagtatcta ttaacgaacc tgtcgttgtt
    76861 gccacttgtc caattgactt caatgtaaca tctacactgt ttgtgatgct tggtatcgca
    76921 tctttcagct gagaggcacc tgattttgtt tggtttgcta gatcacttgc ctgattttct
    76981 aaatttttca catctggcaa gatatcttgt acttgttgga tgatcgtcaa gccttgtttt
    77041 gcttcatcga ttccttggtt cattgtctct tggatcgaag caaaatcgcc gtcgatctct
    77101 gctagttgct taccggcatt ttggatctct gggatttttt cttgcaaatc aaggatgatt
    77161 tttgcttgat ctttcaactc aggcattttg tcattcaatg caacgacttt ttcacccatc
    77221 tcatctactt tagggatgta atccacgaat tcatttgctt tattcagttt ttccttgatt
    77281 tcaggtagtt gactttgtaa ttcgaggact tgttttgtgt agccgtcgat cgtgtccaaa
    77341 ttttcatctg ttgataaaat catatcttta actttattga tacttactag gttcgtatcg
    77401 atgtcgtaac ctatctcatt gaatactttc aataaagtcg aactggctgt tttgataaat
    77461 tcatttgtga tttgcgattg gatcgaactt gctcctttat cggtgatttt cggtgcaatc
    77521 gcattgattt tttcatttac cgtatattcg atttttggtt tcttgatatc accactagta
    77581 aaactcagca gatcttctga gaaatccttt ggcaagtaaa tacctgcgta atactttccg
    77641 gaacggactc cgtcttctaa ttgttctttt gaatcaacga attgccatcc taattgttta
    77701 tttttatgaa gcgattcgat gacttgctcc ccaatggcca cttctttacc ttgaaactct
    77761 gctggcttgt ctgcactgta aacagcaatt ggcagctctc cagtatttcc atatggatcc
    77821 cataatgctt tgatgttaaa ccacgcatat agcgaaggga tgatcatgat cgcgatgatc
    77881 agaagtgttg caatcgggtt tttgaaaatc cgtttccagt caagcaaata taatcgaagc
    77941 gtatttttga ttgactgcat agttctcccc cttcttcttt tttcagctga attactttac
    78001 catgtatttc atactttttt caatcggctt ttttcaaaaa agtcgaattt ttggacatat
    78061 cacggcaatt gtctcattgt aatctcttac atattgagaa ataattaagg attacagcct
    78121 ttactttatc atgaaataaa agggaaagat aattttatgc caaagttttt atctattata
    78181 cgtatacgca aaaaagctaa aacatttttt gtctttgccc ctacaaaaat gtttcagctt
    78241 ttttcgtttt ttattcctgt atttcttatt tttcgaatga caggatgatt ttcccagcag
    78301 gaggatgtcc ttcaactagc tgatgtgctt ggatgacatg cttaagtgaa gcagacagat
    78361 tcattgaaat aaaaacatga aaggctcctt tttggtaggc tttgattatg ccagcaaagg
    78421 cttctgcatc tagatattcc tttcttggaa caaacgattc ataaaagcct tccttttttt
    78481 gccgcaaatc tagatctggg aggtcattta atgcaacata cctgccgcct ggtttcatga
    78541 tctggatgcc ggtttctcct ttgatacttc ctttcgtcgc atcgattaca aggtctgcct
    78601 gatcagcaaa ttgcagacct ggatttgttt tatcataagc agcaaatgct gaagctccta
    78661 atttttttac cttttcctca tttttactgg atgcactggt taagattcgg attccctttt
    78721 catggagaag ctggatcaga cttgacccga ccgcacctga tgctcctagt atcattacag
    78781 tatctgtcgg ctggatttcc gtcaaatggt tgattagatt ataagccgta attcctggcg
    78841 tgaccattcc ggctgcttct tcccaactca ttttatctgg aatttttgct acttttgctg
    78901 atggcaacac gacttcttct ccgtaagtcc cgccgactgc atggacagct actcgatcac
    78961 ctacatgaac agttgtgaca tctgaaccaa tctctgtcac aataccagcg ccatcattac
    79021 ctggtacata agggaatttc aatgttcgta tctctttcat ttctcctaaa cgcaaggcaa
    79081 catcataagg attcacactg aatgctttta tttctacacg aacatgtcca gaaccgactt
    79141 ctctgggatg agcatcgatt tcttcaaaaa catcttgtgc ttctccgtaa ccgttaattg
    79201 caaatcttcg catggtcacc atctcccttt ttctttaagt ttacgtttat gcctttattt
    79261 tgacaaaaaa aatgtctttt cgttttggcg catgattcaa aacaaaatag ttgtcttttt
    79321 tcgcgtaacg tgttaaatta tttatctaaa agcgtaaaga ttacgattta cgctaataaa
    79381 aaataattgg aggaatttgt tgatggctaa aaaatcaaag attgccaaag caaaaaaaca
    79441 gcaagaaacg attgaacgct atgctgcttt acgccaggaa ttaaaagcgc aaaaagatta
    79501 cgaaggcttg cgtaaacttc ctttagatgc tcgtccagaa cgattgaaaa atcgtgattt
    79561 aatcgatgga cgccctcgcg gatacatgcg taaattcggg atgtcccgta taaaattccg
    79621 tgaattagca cataaaggtt tgattccagg agtaaaaaaa gccagctggt aatccaagtc
    79681 tggctgtaat gtaaaggagg agggcgcatg gaccactcct tggatcatca aaaaagatac
    79741 gttcgcttct tctagcagaa atgctggtac tagaagcaga cgtatctttt tttacgcaca
    79801 gctggtcctt ttttatatgt aaaggctgca tggttacttc gctatattta tttagtaaca
    79861 ggagtcagtg cttcgatacc cacactaatt ttcaatgctc ggtcaacttc tgccataatg
    79921 ggtcgatcca aatggcagac cttttctttc aatcttgatt tatcgatcgt tctgatctgc
    79981 tccaacagga taacggagtc tctttctatt cctgttccag tagctttgat cccaatgtga
    80041 gtcggaagct taggtttagc catttttgcc gttatggccg caacaatgat cgtcgggcta
    80101 aaatggttac ctagattatt ttgaataacc aaaactgggc gtgttccgcc ttgctccgat
    80161 cccacgactg gagaaagatc agcaaaataa atatctcctc tttttaccat aggatcctcc
    80221 ttattcttga tattctcttg gtatccgctg tcctaatccg caagccactt catagtggat
    80281 cgtacctaat tgatctgcta tatcctgcat agtgatttct ttgtctgcat ttttgccgat
    80341 aagcgtcact tttgttccga caggaaattc ttgaggcaat cggatcatca gttgatccat
    80401 acatacacgc ccaatcgttt cacagtagtt cccttctacc aatagagaaa aaccctgcat
    80461 ctttcgtggc cagccatctg cataaccgat cggtatcgtt ccgatccact ctgcttcagg
    80521 agtgatatat gtttctccat agccgattcc ttcacctgct gggagttttt tgacttgaat
    80581 caattcagaa accagctcaa gtgctggctg caatggataa acttccggta gtgcgtgccc
    80641 agagggatta agtccgtaca ttgctactcc ataacgaatc atattgccga ttgtttcatc
    80701 atgccataaa gccgttgcac tattgctgac atgtacatat cgaggaagtt cgggaagttt
    80761 tttcagcact tctataaagc gttctttttg cagattccaa tatgtatcat ctgcctgatc
    80821 tgctgtagaa aaatgggtaa ataaaccttc ccattctaat acacgacttt ctttgatgaa
    80881 tgcagctgcc tcttttactt cttcaggtgt acaaaatccg atacgaccca tcccagtgtc
    80941 tgcttttaga tgaatcgaaa gaggcgtctc tagcttactt ttctctaaaa cagcagctgc
    81001 tgcttgcaac cattcccgtg tacctgcagt tactgataaa tcatgagcaa cagctacagt
    81061 cagtgcgtcg taaggaacca tattcaagat aaggatgggc tgagtaaatc cagcttctct
    81121 caactcgact ccttcatcta aatttgaaac acaaaagccc gaagctccac ctgcaactgc
    81181 tgcctcagct gtttcaatag ctccatgacc gtatccgttc gcttttacta ctgcaaacaa
    81241 ttcttttcct tgcggaagtc ttgcaacttc atttgctaca ttttcagtta tagctttttt
    81301 atgtatcact gctttcgttg ggcggtgcca agcgacaacc atcgtttttc cttctttcta
    81361 gtcttccaaa ataatttgtg caaaagctgt ttcatttgta tgagtaatac tgacccatac
    81421 attgccttca tgaggtgaac gcgtcacaac aggctgacca ttttcatttt ttaaaatctc
    81481 gacatcttga aaggtaactt ttccgatccc agttccccaa gctttagaga aagcctcttt
    81541 gcaagcgtaa cgcccgccta aaaattctac ttggcgatga aaaggcaagg actggaatag
    81601 tttcatttca tcagaggtca agattcgtgc aatgaatttt ggtttttctt cgatcagccg
    81661 agtgatccta ggaagttcga ctgcatcgat cccaattcct tttatcatat gcttttctct
    81721 tttcaataaa tttagaacac tctcattcta ccaaattata accattttgc cacaaataag
    81781 tccacaaata acaaaaatga aagtttctct taaaaaagag aaactttcat tttatgttta
    81841 atcgttattt gaacggatta caaatccgcg ttttttatca ttgtgacgtt taccgccatc
    81901 tttttggctg ttattatttt tgctataacc gccttttgat ttgtttccac gataattacc
    81961 gccgtcacga cgattacggt tgtttccgcc accacgtttg ccatttttat tgtatccttt
    82021 tttctgcatt ggcaatgggc gttctggtgt gatcttcact ggcactgcat cagctggatc
    82081 ttttgctgtc gtttttagca aaagtgcaac taaatcttgt gcagaatatt cttctaataa
    82141 tttatctgct gtttgcaggt atttatctag accattttct gcaagttttg tttcgatttg
    82201 ttcaactgca gcacctaatt gacctttgaa tgcttctttt tcggttggtg gacgtaaagt
    82261 cgtcatccgt tttttcgtca agttttcaat cacatgcaag tagtccattt catttggtgt
    82321 aacgaaagtc acagacatac cgccttttcc ggcacggcct gtacgtccga tacggtgaac
    82381 gtagctttct ggatcttgag ggatatcata gttgtacaca tgagtgacac ctgaaatatc
    82441 taatccacgt gcagcaacgt ctgtcgctac aaggatatct aaatgaccgc tcttaaatga
    82501 acgcaatacg ctcattcgtt tttgttgaga caaatcgcca tggattcctt ctgcacggta
    82561 accgcgtgct tctaatccgc gtgccaattc gtctacacgg cgttttgtac gtccgaagac
    82621 gattgttaat tcaggtgttt gaacatcaaa caagcgagtc atgatatcga atttttcgta
    82681 ttcttttgcg cggacatagt attgatcgat caagtcagct gtcatttctt tcgctttgat
    82741 cttcacatga tgtggatttt tcatgaattt aacgccaata ttcttgatag ctggcggcat
    82801 cgttgctgag aaaagtaatg tttgtctttg atcaggaact tgtgaaatga ttttttcgat
    82861 atcttccaag aagcccatat tcaacatttc atctgcttca tccaaaacta atgtttgaac
    82921 ggttccaagt ttcaatgtgt ggcggttaat gtggtcaagc atacgtcctg gtgtacccac
    82981 aacgatatgt ggacgatctt tcaagccacg gatctgacgg ccaatatctg ctccgccgta
    83041 aacggcttgt acacgtactt ttttgtcgcg ccctaaacga tataattctt cttgtgtttg
    83101 gatagctaat tcacgtgttg gtgcgataac taaaccttgt aattcgtgac gatctggatc
    83161 gattttttct aacattggta atccaaatgc agctgttttc cctgtacctg tctgtgcttg
    83221 tccaataacg tcttttccag ctaatgctag tggaatcgtt tctgcttgga taggcgttgc
    83281 ttcttcaaaa ccagcgcgtt cgactgattt caacaattct ggtgataatt ctagttcttt
    83341 aaatttcaaa tgaatcctcc tatatggttg ttaactgagg atgtagcttt tttgctaccc
    83401 cgtcgatttg ttcggtcaaa gtgtattgtt tctttttgac agtggccacg cacgttttta
    83461 tccattctta gcccctgtgg caccaccgaa aaatcacttt gcgaagttta ggcattagaa
    83521 aagccaaacg ggtcgcgttc agctttatca ttattatgac atctggcttc aacaagttgt
    83581 ttctatggca aaaccagtcc aatttctctt catctttcgg caataggtta ttctaacata
    83641 gtttttcgtt ttctgcaagt ttacagattt ttatttcatt tgctgaagtt gttctaccac
    83701 ttcaaataag cccatgctgt tgctgccttt tagcataata ctatctgttg cttcaagatt
    83761 ttgtttgata gcatcaatca atttattctt ttctttttca aaatagaaca caggtagttg
    83821 ggggtatttt tggttcaatt cttcttttag tgcatgcatt tgttccccat aaaggaaaat
    83881 catggcgaat ttctcaggat cgatatgttc actcatttgc gcatgcatat ttaaagactc
    83941 tttccctaat tccagcatat ctgctaacac agcgattctg cgtccttttg ttggcagatt
    84001 tttaaaagta tctaatacca gtcccatggc tgttggattt gcattgtaga catcgctcaa
    84061 aatagctgca ccatttcctg ccgttagcca ttcggttctg ttttgagtga tagaaacatg
    84121 ggcgagccct tggcgtatct caggtatgga cagtccaaag aagcgcccga tcgtatacgc
    84181 aatcaaagca ttcgttacat tataacttcc aggcagcggg atcgtaaatg tttctccttc
    84241 tactacaaaa tcggtttgtg cttttccttt tgctgtcact tccgcatgaa catcgccatt
    84301 tccaataccg aatgttgtga ctgtttgtac taatgttgcc gttaaaggtg tcagcaacgg
    84361 ttcatctgcg ggcacaacga gtaatccgtc tgatacaagt ccgtcagtga tttccatttt
    84421 ggctttagcg attccttctc gcgacccaag attttctatg tgtgcttcac cgatcattgt
    84481 gattgctgca gcttttggtt gagccataag tgaaagttcc gtgatttcat tggcgtgatc
    84541 catgcccatt tccaaaacga tcttttctgt atcttggggc atgtgcaaaa tcgtgtaagg
    84601 aagaccaata ttattgttgt aatttccttg cgtcttatat gttttgtatt tttcagacaa
    84661 gacagacgcg gttagatctt tcgtggtggt tttaccattg cttcctgtaa ttgcaacgac
    84721 ttctgcgcct actttttcca agtaataggt tgccaattgc tgcatggctt tcaaaggatc
    84781 tgctacagga ataactggaa aattttttgg agcttgttca acaggcaagc tccaaaatga
    84841 agcagatgct ccgtttgtga tcgcttgctg gataaattca tgtccatctc gcgtaccagc
    84901 aagaggaacg aataaacttc cttcggttat cttccggctg tcaaattcga cattggtaat
    84961 ctttgtcagt gcagagcatt cgctgcccac ggcttgtgca atttcttgta ttgttagatt
    85021 cattgagatc tctcctaaaa aaggttgtga aaaaagcgtt tggcctaaac ggcgggttcg
    85081 catgactctc acttccaagt aaatttctct attcgtattt agaagctaga atgaacgcgg
    85141 ttacgcaatc actccagcct cttctttatt tctctttatt catttttttc aaaaaaagat
    85201 tgacgctgat ggtatcgatt cattcctaac tggatcagtt cttcaatcaa atcaccgtat
    85261 ttcaagccca tattttccca taagagtggg tacatactga actccgtaaa tcctggcata
    85321 gagtttaatt cattcaggaa taattcattt ttatttgtca aaaagaaatc gcaccggctc
    85381 aatccgcttc cacctaacat cgtgtaagct aacttcgcgt actcttgcgc tttttgataa
    85441 acttcttctg gcacttcggc tggaatctgc atttcgattt tattattgat atattttgct
    85501 tcataatcat agaatgctac gtcttttacg acttcaccag gcaaagtcgt ccgaacgtct
    85561 tcatttccta atacagcaac ttcgatttcg cgcgcttcaa ttccttgttc aacgattgct
    85621 cgagaatcat actgataggc tgttgctaaa gcattttgca gctcttctcg gttttctgct
    85681 tttgtaatgc cgacactaga acccatattc gccggtttga caaacatcgg ataaagcaaa
    85741 gaaccttcac attgatcaaa tactttttta ggattttctt tccattgatt cttaagtact
    85801 ggtacataag gaacttgcgg cacaccagca gcttgtaaaa tatacttggt catgatttta
    85861 tccatggcac atgcactggt caatacgcct gcgccgacat aaggcatatt caatgtctct
    85921 aagaagcctt ggatcgttcc atcttccccg tttggcccat gtaaaactgg aaaaacgatg
    85981 gctccttctt ctttgatttc gcccggattg atcacttttc ctgtaaagcc ttcctctgtc
    86041 tgtccacttg ggtcccatga aagatgcaag acatctttgc tggcaggttt ttctgttagt
    86101 aatggacctt tgacccattg tccttctttt gtaataaata cgagttgaac ttggtaataa
    86161 ttataataaa tggcatttaa aactgaaaat gcggaaagaa tggacacttc atgctctgcg
    86221 ctgcgtccgc catatagtaa agtaatcttc aaaagattgt cctcctgtat tctaaatcgt
    86281 tcagtgattt actctcatat tttagcacaa aacaaaaata aacgaataac ttatttataa
    86341 aaaaacgagc cagcttctaa aagaacgagc gtcatttatt ttttgtcagc tagattattt
    86401 gtcccgtttt ttataaaaag ttatgataaa gaaaaggagg gatgatgatg gcgcaaacaa
    86461 atccacgcag ccgcttggca gaaatcattc gagtgttcat caattacaat gtagtgccaa
    86521 actttgtaca gcaaaaaaat cccgaacagg taaaaaaagc ctttgaagaa ctaggcccca
    86581 ccttcatcaa gataggacag atgctttctg ttcgagaaga tttgctttct tctgccttca
    86641 ctcaaacatt caaaacatta caagatagtg tacctagcga cacattttca acggtcaaaa
    86701 agacgatcga aacagaactt tctctttcat tatcagatat attcgatgat ttttcaaaat
    86761 cgccttttgc ctctgcttct atggggcagg ctcatcgtgc caagctgaag aacggtgacg
    86821 cggtagtcgt taagatccaa caccctaaca tcgccgaaga gatccgactt gatcttcaac
    86881 tatttgaacg agcgatccct ttgatcaaat acattcctga aactagcgta gttgatctaa
    86941 aaggggtact ccaagaagta aaacgttcct tgatcaatga aatggacttc ttaaaagaaa
    87001 gtcaaaatgg cgaacaattc tatcaaaaga acaatggctg gaaagagatc cgcagcccca
    87061 agatttatga cgctttttgt tcgaaaaaag tgatcgtgat ggaagaaatg tctggtaaaa
    87121 acttgaatca tttaatgaac gccgaaaaca aaactgaaac ttttatcact ggaattcaaa
    87181 acaagcagct gaaacaagaa gttgcaaagc ttttagttga gaactttatg aaacaggtgt
    87241 ttgatgatgg ttttttccat gctgatcctc atccagggaa tctgctattc catgtactaa
    87301 caaaagaaga acagacacaa gctagccgaa aaactgaaac agtccatgaa aaagagttcg
    87361 gttcctttgc ttttcgagcc tccacttctg cagaagaccc tgttgcgcca tataccatca
    87421 actacatcga ttttggtatg atggggcatc tttctgcagg acttaggcaa aaactcacac
    87481 aagccgtttt agcgctgtat acgaaagatg cttatcgaat cgaaaaagcg gtccttcgac
    87541 tttgtcagca agaaggctcg tttgatgaaa gtcggttcca ccaagaactg acaagttttc
    87601 ttgaacagta ttatgattct cctattgatg aaatcaactt gcaagaagta ttcacacatg
    87661 tcgtgacgat ttgtcatcaa aataatctgc agttcgatcg tgatatcacg cttttgctga
    87721 aagcatttgg gacattagaa ggggtgatcc gcgtcctcga tcctgaagtt tccctcatgg
    87781 aagtcgcttc gccttttgct caacattatt ttctcactca tctggatgta gaagatacat
    87841 tgaaacaaag cggattagac ttattggaag ggatgaaggc tgcgcctaag atccctcaac
    87901 agctccacca tctattagaa atgtggactt cgggacaagg aaaagtcaat ttggaattga
    87961 aaaagcaaga caaattattg agcaggatcg aaagtatgat caatcggctt gttttcggta
    88021 tgattttagc tgcattgatc gtagggtcct ccctgcttgt ccaagcagca cctgtagaaa
    88081 acgcagaggt cgtttcctta ttagggatat ttacgtatgc tattgccgca ttcgtcatta
    88141 tttttttggc aatcgatgca ttgatccaaa tgtataagaa gaggaaaaag tagaaaaagg
    88201 ttgtgacaga aagaatcagc ttcaagaaat aagaaggggt tttacataaa ttgtttctca
    88261 aatttttgtg aaaattcggc ttatttttcg aagaggctac ttctgaaaca ccgagaataa
    88321 aaaatgtgaa aaagctgttc tgcacccagt aataagaaca atcaaaaagg gaacatggaa
    88381 cacatttatc ctgtttccct gttccctttt tgatgtattc gagcataaat aaaatacctt
    88441 cgttacctac tatcttctgt acttggtaaa ccttagtcaa ttgccttttt taacgcttga
    88501 cgaaaagaca tatgatcttt ctccgtaaag ggttttggac cctttgtcct tatgccagct
    88561 tttcttaact ttccactatg ataacgttgt tctagaagcg tgccgatatt cgcttcgtca
    88621 aattcttttc cagagtgatg gaacactcgc acacccttcg gcaatacaag tgaagctaaa
    88681 ccataatctt gcgtgatcaa aaagtcattc ttcttaacca taccgacgat tttataatcc
    88741 gcactatcag ctccgcggtc tacgtagacg atttggacat gattagcgta ttctttggtc
    88801 gtataatggt ccacactggt cacgataacc acgtcaagac cataggattc tcctaatttt
    88861 atgacatctt cttttactgg agaaccatct ccatcaatga atagcctcat tctttttcgc
    88921 cttcttccat aaatgataaa cagttactaa tccgctcagt aaaagaccaa cattgatcca
    88981 ttttgccaag ataagcagtt gtacactttc tatcggcact gattcatggt tcagcgtgat
    89041 caataataga tggattggct ctcccatttc ttttgctaaa acaaacaaaa gcgtcatcaa
    89101 taaaaactgg tggatcacac tccctttatt ttgagtagta tacttgacaa cgatccggcg
    89161 atccattgga atagctgtat cagtttgata atattcctta tttagccagc tgcctgttac
    89221 tacgtgccag aaactaagca gaaagacacc tatcgcaaaa ccatttggaa tcaagaggac
    89281 caataaagaa gaactcagtc caagcaattg catagccaat ggagaccatg ttaaacgttt
    89341 caaaatccat ggtccgacta tttttgctgc aatcaagcct gctgcataag gcaaatacat
    89401 aaaaatcgaa agtttttcta atccgtacag tatgccaaca taaaaactgc taaataaaaa
    89461 aaggaaattc cctagcattc catttagaaa agtaaacaga tttagccagc ttggcaactt
    89521 ccattccttc ttctggtgtc ctaaaacaaa cacgaacaag atgaacagca gcaagaaacc
    89581 ataaatagca agatcaaaaa gcctttcatc gaataacaat cgggcatttc tcaaaagaaa
    89641 caataagcca aagaatatca aaaataaaac aagctctcgc gtagctacca gatttctttt
    89701 gatgtctttg aaatccagtt cgtaacgcgg ataatgacta accgtatggt aggccatgac
    89761 gtaaaaaagt gtataaatag taaagcttgc tgcaatctga gtcggtgcag gcaactcaat
    89821 cgcttgatac aggagaaata gccagatagc tgcaaataag tactttttcc catccatatt
    89881 gataaaacct tgcgtctttt cgtgaaaatt gaccgtggta ttagcaggta caagccatgc
    89941 tgcactcagc cctagcaaaa cacttgaaaa ataaaataaa ggaaaataaa atacgcctaa
    90001 tattccaagc aatgaaccag caccaccaat cagcagagcg atcatcagca acgtgtaact
    90061 atctagacca aatcgtagac tgttgactaa aaatagtcca gtcatccgaa aggcataaaa
    90121 cagcgtaaat ggcaaaatcg tcagccaatt atgcgagtct gttagtccca aaaataaaag
    90181 ataaggaata aaaataaccg tgttacttaa gataaagggc gttgtttgtg taaaattacg
    90241 cccaaatcgt ttgagttttt cgaacatgac aatggctcct taaacagtct tataactaat
    90301 ctgctcttcg attttagcat taaaggggaa ataaaccaat tttacagaat atattcttgt
    90361 aaaaaaaaat acagaaagaa gcataagctt ctttctgcat ttttacggta cttgattact
    90421 caagcagaca agcccttctc cacaaaagtc ttgcccgaca cccctgcatc cggcaggtga
    90481 taaagataga aatcaattat cctgtgcctc caaaatcaat taggagctct gtaaaccaga
    90541 gtccttctcg acccgtcgca taaatttact ttaacacagt tcctatgttt atgcgagagc
    90601 ttttttcatt ttataatcga ccatttgaaa tccttgaccg atatctgaaa taagttcttc
    90661 tgtaatctca aatccttcat gcttataaac ctcgattgct tgatgattcc cctgattcac
    90721 tcgcaaaaag atctctcttt cctttgtttg cgcagcaagt tcttcatacc agcgaaaaac
    90781 tgaagaagtc aatccttgac cacgtacttt atttagcaaa tataatttac ttaaataaat
    90841 ttttccattt atctcttcat aagcagtgta accgacagtc ttttcttcgc tttttaataa
    90901 aaagtaggac acaccttctg tcagttcttt ttgaatctgt ttttttgact gataagtttt
    90961 cagcatgtaa tccacttgtt tttgaccaat gatcggcaca aaaacttccg gccatacttc
    91021 ttgtatgact gccatcagct catccagttc attttctgtt acttttattt tttccataca
    91081 cccacgtcct tttttacatt ataaatgacc ttgcgcttga tggaataaaa agagcatgat
    91141 catgctatac acacccaccg accacggttt caagaaaatc acaatctgca taaattccct
    91201 aaaagataat ttcgtcaaac cagctactag acagatcaag tcgtctggcg caaagggaag
    91261 cagcaaggta acaactagta cttttttaat atctttcgtt tttcttgtca gcaattcatc
    91321 aaatttctga tacttttttg gcgataaaat aagctggaca aaggctacgc catagtaacg
    91381 gacaagcaaa aatccgattg cttccccaat cactaggcca atacaactat ataaaagccc
    91441 aaatccattg ccaaacatca gcatgcccgc tactgaggag atccctcccg gcaaaatagg
    91501 aatgatcact tggatcactt gcaacagaac aaatatcatc actgcatact tgccaaattg
    91561 ctggataaac gcttgcaaag acgtgctcga tcgaaaaatc ccatgatgat aagcataaag
    91621 aatcaacaca aagaaaaaaa acagaccaat aatgggcatg atctgaagac atttttgtaa
    91681 aactgatcct tttttagaca tctatattcc ccacatcttt tttcatttat taaaactgcc
    91741 tccttatgaa ctgaacccca aaagttgaac tatttaatgg actgtttccg atattctact
    91801 ggagatagtc catttaactt tagttttatc cttttgttat tataccacct aatatactca
    91861 tttaatttac tttgaaatat ctcaattgat cggaattttt ctcgataaaa aaactctgat
    91921 ttaagcacac caaaaaaatt ttctattaca gaattatcta agcaatttcc ttttctagac
    91981 atgctttgaa taatgttatt ctcttttaat tttttttgat attgtggcat ctgatactgc
    92041 catccttgat ctgaatgtag aatcagtgaa ccctcagttc cctttttttt aattgcttgt
    92101 tgaagcattt cttcaatcag tttatatgtt ggactagttg atatactata actaattatt
    92161 tctccgttaa ataaatcaag tataggagat agatagattt ttcttccttt tatcttgaat
    92221 tcagtgacgt ctgtcaccca ttttttattg ggtgtatcta ctgaaaaatt tcgttttaac
    92281 acattcttgg caatttttcc tactgttcct ttataagatt tatatcgctt tattcggatt
    92341 tgacaggtaa gtcccatttg ggacattaat tttctaactg ttttatgatt gattgtatat
    92401 cctttcatct ttaacgctaa agtgactcta cgataaccat aagagtttct tgattctttt
    92461 acaatcgctg taatttcttg ctttatcttg ctatatttat ctggcttatc taattttttt
    92521 acccagtaat aataagttga cttcgctaat tgtgcaattg aaagtaatag attcaattta
    92581 aattcttttt tgagctgaag gattgtttta accttgattt cttcttgctc aaatcttgtt
    92641 cttgaatcaa ggtttct
//
LOCUS       DAPBBV010000007        72219 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.007, whole genome shotgun sequence.
ACCESSION   DAPBBV010000007 DAPBBV010000000
VERSION     DAPBBV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 72219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.007"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..1086
                     /locus_tag="RD486_000651"
     CDS             <1..1086
                     /locus_tag="RD486_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7662408.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1304..2446)
                     /locus_tag="RD486_000652"
     CDS             complement(1304..2446)
                     /locus_tag="RD486_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7662409.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2451..2636)
                     /locus_tag="RD486_000653"
     CDS             complement(2451..2636)
                     /locus_tag="RD486_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HDT7662410.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2990..3235)
                     /locus_tag="RD486_000654"
     CDS             complement(2990..3235)
                     /locus_tag="RD486_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7662411.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3229..3630)
                     /locus_tag="RD486_000655"
     CDS             complement(3229..3630)
                     /locus_tag="RD486_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7662412.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3817..5625)
                     /gene="uidA"
                     /locus_tag="RD486_000656"
     CDS             complement(3817..5625)
                     /gene="uidA"
                     /locus_tag="RD486_000656"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HDT7662413.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5648..7414)
                     /locus_tag="RD486_000657"
     CDS             complement(5648..7414)
                     /locus_tag="RD486_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HDT7662414.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7427..8221)
                     /locus_tag="RD486_000658"
     CDS             complement(7427..8221)
                     /locus_tag="RD486_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7662415.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8231..9607)
                     /locus_tag="RD486_000659"
     CDS             complement(8231..9607)
                     /locus_tag="RD486_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7662416.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9727..10374)
                     /locus_tag="RD486_000660"
     CDS             complement(9727..10374)
                     /locus_tag="RD486_000660"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HDT7662417.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10458..11885)
                     /gene="uxaC"
                     /locus_tag="RD486_000661"
     CDS             complement(10458..11885)
                     /gene="uxaC"
                     /locus_tag="RD486_000661"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDT7662418.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11959..13038)
                     /gene="uxuA"
                     /locus_tag="RD486_000662"
     CDS             complement(11959..13038)
                     /gene="uxuA"
                     /locus_tag="RD486_000662"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7662419.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13041..14672)
                     /locus_tag="RD486_000663"
     CDS             complement(13041..14672)
                     /locus_tag="RD486_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDT7662420.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14976..15647
                     /locus_tag="RD486_000664"
     CDS             14976..15647
                     /locus_tag="RD486_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7662421.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(16372..16707)
                     /locus_tag="RD486_000665"
                     /pseudo
     CDS             complement(16372..16707)
                     /locus_tag="RD486_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16804..17256)
                     /locus_tag="RD486_000666"
     CDS             complement(16804..17256)
                     /locus_tag="RD486_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662422.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(17263..17811)
                     /locus_tag="RD486_000667"
     CDS             complement(17263..17811)
                     /locus_tag="RD486_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDT7662423.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(17856..18188)
                     /locus_tag="RD486_000668"
     CDS             complement(17856..18188)
                     /locus_tag="RD486_000668"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662424.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18202..18459)
                     /locus_tag="RD486_000669"
     CDS             complement(18202..18459)
                     /locus_tag="RD486_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662425.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18654..19196)
                     /locus_tag="RD486_000670"
     CDS             complement(18654..19196)
                     /locus_tag="RD486_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662426.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(19217..20308)
                     /locus_tag="RD486_000671"
     CDS             complement(19217..20308)
                     /locus_tag="RD486_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDT7662427.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20316..22526)
                     /locus_tag="RD486_000672"
     CDS             complement(20316..22526)
                     /locus_tag="RD486_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662428.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPFPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(22542..25070)
                     /locus_tag="RD486_000673"
     CDS             complement(22542..25070)
                     /locus_tag="RD486_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7662429.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(25122..25532)
                     /locus_tag="RD486_000674"
     CDS             complement(25122..25532)
                     /locus_tag="RD486_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662430.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(25545..25763)
                     /locus_tag="RD486_000675"
     CDS             complement(25545..25763)
                     /locus_tag="RD486_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662431.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(25760..26752)
                     /locus_tag="RD486_000676"
     CDS             complement(25760..26752)
                     /locus_tag="RD486_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7662432.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(26831..27742)
                     /locus_tag="RD486_000677"
     CDS             complement(26831..27742)
                     /locus_tag="RD486_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7662433.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(27761..28105)
                     /locus_tag="RD486_000678"
     CDS             complement(27761..28105)
                     /locus_tag="RD486_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662434.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28125..28681)
                     /locus_tag="RD486_000679"
                     /pseudo
     CDS             complement(28125..28681)
                     /locus_tag="RD486_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28762..29262)
                     /locus_tag="RD486_000680"
     CDS             complement(28762..29262)
                     /locus_tag="RD486_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662435.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(29263..29808)
                     /locus_tag="RD486_000681"
     CDS             complement(29263..29808)
                     /locus_tag="RD486_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662436.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(29805..31061)
                     /locus_tag="RD486_000682"
     CDS             complement(29805..31061)
                     /locus_tag="RD486_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7662437.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(31422..31733)
                     /locus_tag="RD486_000683"
     CDS             complement(31422..31733)
                     /locus_tag="RD486_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662438.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(31756..33066)
                     /locus_tag="RD486_000684"
     CDS             complement(31756..33066)
                     /locus_tag="RD486_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HDT7662439.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(33680..34132)
                     /locus_tag="RD486_000685"
     CDS             complement(33680..34132)
                     /locus_tag="RD486_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662440.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(34134..34499)
                     /locus_tag="RD486_000686"
     CDS             complement(34134..34499)
                     /locus_tag="RD486_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662441.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(34598..38881)
                     /locus_tag="RD486_000687"
     CDS             complement(34598..38881)
                     /locus_tag="RD486_000687"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HDT7662442.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(39028..39267)
                     /locus_tag="RD486_000688"
     CDS             complement(39028..39267)
                     /locus_tag="RD486_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662443.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(39357..39629)
                     /locus_tag="RD486_000689"
     CDS             complement(39357..39629)
                     /locus_tag="RD486_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662444.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(39712..39963)
                     /locus_tag="RD486_000690"
     CDS             complement(39712..39963)
                     /locus_tag="RD486_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662445.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(40959..41870)
                     /locus_tag="RD486_000691"
     CDS             complement(40959..41870)
                     /locus_tag="RD486_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7662446.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(42066..43901)
                     /gene="lepA"
                     /locus_tag="RD486_000692"
     CDS             complement(42066..43901)
                     /gene="lepA"
                     /locus_tag="RD486_000692"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDT7662447.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            44048..45268
                     /locus_tag="RD486_000693"
     CDS             44048..45268
                     /locus_tag="RD486_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662448.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            45288..45782
                     /locus_tag="RD486_000694"
     CDS             45288..45782
                     /locus_tag="RD486_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HDT7662449.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            45760..46446
                     /locus_tag="RD486_000695"
     CDS             45760..46446
                     /locus_tag="RD486_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662450.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(46597..49206)
                     /gene="clpB"
                     /locus_tag="RD486_000696"
     CDS             complement(46597..49206)
                     /gene="clpB"
                     /locus_tag="RD486_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDT7662451.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(49457..50503)
                     /locus_tag="RD486_000697"
     CDS             complement(49457..50503)
                     /locus_tag="RD486_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDT7662452.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(50514..50786)
                     /locus_tag="RD486_000698"
     CDS             complement(50514..50786)
                     /locus_tag="RD486_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDT7662453.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(50821..51729)
                     /locus_tag="RD486_000699"
     CDS             complement(50821..51729)
                     /locus_tag="RD486_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDT7662454.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(51861..53093)
                     /gene="pepT"
                     /locus_tag="RD486_000700"
     CDS             complement(51861..53093)
                     /gene="pepT"
                     /locus_tag="RD486_000700"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDT7662455.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(53108..54229)
                     /locus_tag="RD486_000701"
     CDS             complement(53108..54229)
                     /locus_tag="RD486_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDT7662456.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(54226..54927)
                     /locus_tag="RD486_000702"
     CDS             complement(54226..54927)
                     /locus_tag="RD486_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HDT7662457.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(55071..55511)
                     /locus_tag="RD486_000703"
     CDS             complement(55071..55511)
                     /locus_tag="RD486_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDT7662458.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(55640..56566)
                     /gene="dnaI"
                     /locus_tag="RD486_000704"
     CDS             complement(55640..56566)
                     /gene="dnaI"
                     /locus_tag="RD486_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HDT7662459.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(56566..57939)
                     /locus_tag="RD486_000705"
     CDS             complement(56566..57939)
                     /locus_tag="RD486_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDT7662460.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(57962..58453)
                     /gene="nrdR"
                     /locus_tag="RD486_000706"
     CDS             complement(57962..58453)
                     /gene="nrdR"
                     /locus_tag="RD486_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDT7662461.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(58765..59097)
                     /locus_tag="RD486_000707"
     CDS             complement(58765..59097)
                     /locus_tag="RD486_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDT7662462.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(59149..59778)
                     /locus_tag="RD486_000708"
     CDS             complement(59149..59778)
                     /locus_tag="RD486_000708"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDT7662463.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            complement(59742..60578)
                     /gene="mutM"
                     /locus_tag="RD486_000709"
     CDS             complement(59742..60578)
                     /gene="mutM"
                     /locus_tag="RD486_000709"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HDT7662464.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(60623..63268)
                     /gene="polA"
                     /locus_tag="RD486_000710"
     CDS             complement(60623..63268)
                     /gene="polA"
                     /locus_tag="RD486_000710"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDT7662465.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(63394..64077)
                     /locus_tag="RD486_000711"
     CDS             complement(63394..64077)
                     /locus_tag="RD486_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDT7662466.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(64070..64555)
                     /locus_tag="RD486_000712"
     CDS             complement(64070..64555)
                     /locus_tag="RD486_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HDT7662467.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(64862..66196)
                     /locus_tag="RD486_000713"
     CDS             complement(64862..66196)
                     /locus_tag="RD486_000713"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDT7662468.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(66327..67088)
                     /locus_tag="RD486_000714"
     CDS             complement(66327..67088)
                     /locus_tag="RD486_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDT7662469.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(67104..67586)
                     /locus_tag="RD486_000715"
     CDS             complement(67104..67586)
                     /locus_tag="RD486_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HDT7662470.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(67606..69786)
                     /locus_tag="RD486_000716"
     CDS             complement(67606..69786)
                     /locus_tag="RD486_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDT7662471.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(69930..70661)
                     /locus_tag="RD486_000717"
     CDS             complement(69930..70661)
                     /locus_tag="RD486_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HDT7662472.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(70730..71671)
                     /locus_tag="RD486_000718"
     CDS             complement(70730..71671)
                     /locus_tag="RD486_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDT7662473.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            complement(71851..72219)
                     /locus_tag="RD486_000719"
     CDS             complement(71851..72219)
                     /locus_tag="RD486_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HDT7662474.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
BASE COUNT        21126 a        15161 c        11246 g        24686 t
ORIGIN      
        1 gatatcaatg atgatggctc aagaaaaaaa gtggagaaag ttggcggaga cacccgacca
       61 gaggccgaag ctgctttacg aaaagtttta tcagatattg acgaaacagg acaatacttt
      121 ttaggtacgg atactcgagt aaaacaatac cttgattttt ggatggagga atacgttaaa
      181 ctaaatctaa aatacaatac ctatgaaaac taccgattta ccatcaaaaa tcatataaac
      241 ggttatttag gaaagaaaaa acttacggat ctctcccctg ctcttttaca aaatttcatc
      301 aatgctgaat ttaaaaaggg ttactcgaag aaaacaatga ctattactca ctctgtcctt
      361 aagaatgcgc tgaatatggc ggtttatcct tggggattaa tcaagcaaaa tcctatgctg
      421 tatgtaaaaa taccaaaata tgaagcacga ccaacgacta aaaaagatct aaaaatcatt
      481 tctcttgagg actttgatca tatgctagaa attactcctg aaggacatcc tttctatatt
      541 cctttgaata ttggatttta tacgggaatg cgcgttggcg aagtttgtgg tctgacgtgg
      601 gatgatgtcg atttttcaaa tggaacaatt actgtagaga aacaaatggt aaagaatgac
      661 ggcgcatggg tatatggtac gccaaagaca agcagttcca atcgaacgat ttttattgga
      721 caaaccttgc tagcaattct gaaaaaacat aagaaacaac aattagaaaa tcgaatgaag
      781 tatggaaagc tctacattga ttcaaatgca gtatgtacga aggaagacgg tgagctagtt
      841 acgccaagtg tagtgaaatg gaatactagg aggatatcga atgcactctc cctctctttt
      901 aacttccatt ctctcagaca tactcatgct acacttcttc tcgaaaatgg cgcaaaaatg
      961 aaagaaatct ctgaacgatt gggccacagc agaatttcaa ttacgatgga tacttactcg
     1021 catgtaacag ataagatgag aaatgaaacg gtcgatatca tggaaaatct tagaaagaat
     1081 tcttgatttt tgccaccgaa aaaaaccacc ggtggcaaac cggtggcaaa tccatgtaaa
     1141 catggtttat tttttacact gttttcaaac aaacccttgc tatttcttcg gttcgtcctc
     1201 gtccattttc gataccgaca gctagcttat aacccaaggt atatcaacat aaaaaaataa
     1261 aaataggcta tgacagcagc gtgacagcaa aaaagatgga aagttaaata tcaaacctcg
     1321 taatttcatt tgcgagtgct tgatttgttt ctggatataa gtgtccatat ttgtccaaag
     1381 tagttttaat agaggcatga cctagacgct tagatattgc atagatattt ttattatgtt
     1441 caattaaaaa ggcaacatgc gagtgtctta atccatgcat atgaattggt tttactcctg
     1501 caatttcagc tagttttttt attctgctta aaatagttct tggagatggc ggtaatccat
     1561 caaaagaaaa aaccaattct atatttttcc caattgattg ttgagttttt ttccatgttt
     1621 ttaaatcttc aacggtttgt ctgtctaacg aaattatccg aatacttgat gtattttttg
     1681 tttcagcaaa ttcataatct tgtcttgtac ggatgtaaat tgacttattt acgctacatc
     1741 tgccatttat taagtcaaag tctttccatt gtaacgctaa gagctcctca ctccttacac
     1801 ctgtaacaaa aataaaacgc atcaaacgtt tataaaattc ttcataaaaa tccccgtgat
     1861 aaacactatt atatactttc ttaaattcat caactgtcca aaattctact tgaggacgct
     1921 gagtttttat tttacctata gtatctacag gattttcttc aataatttca agtacaattg
     1981 cccttttaaa aactactctc aacttattga atatctgttt aatataattt ggtgataatg
     2041 gttgctcaat gccctttttt acaacatgga ttttcgataa aaactgttga aattcctgta
     2101 tatgaattgg tcgaatcttt acaacctgca tttctccaaa aaaatccaat gcacgttgta
     2161 aaatatgatc tgttttcata tatgtttttt ctacagttcc caacttatac caaggaaaaa
     2221 aatactctcg ataaaaatca tgaaacgtta ttccttgcag ataaattcct tgtgaatcag
     2281 aaaaactttg ttttaactct tcgagtcccc ttctagcttc tccttgagtt ttgaagcctc
     2341 ttctggtcac ttgaattctt tttccaaagc gatcttgtcc taaagttgca gaaaaaaacc
     2401 aagtgcctct ttttctgtct ttataaacat tcgcaatttt cctcatttta ctattcctcc
     2461 caagaaatat ggagaacttc ttctaaaatt gaaataggaa ttctttttat ttttgaatta
     2521 cgataaaaaa agtatccttt ctcaactaaa agttctttac attccttgaa gattttatta
     2581 gcatagtact gagaaaaacc tagattaatc aaatcttttc gagtagctgt tttcattata
     2641 gcaccttcct tacttttttt catttatttc tatcagctgc ttttgtcaaa agcacatagg
     2701 aatttcacct ctccccaagt ttacggcgag ccttacggaa gtatcattat cccaacttta
     2761 aatcatcgct ttttattgac tataaaaatt attttagaat atttatcgct ccttctttac
     2821 agcaagaaat catggcgcaa ctaaaatatg ctccttaaag tgttaacgta ctgatagaat
     2881 ctatttaatt ttcaatgaac aataggtttt ctacctaaaa gaatctacta attccttaac
     2941 tattagaaga ttcttttaaa cagaaaaagt ggaaagggga tttttttaat tagttaattt
     3001 taaattttaa gatcgcttct attaatttaa tttctagctg acttatcata tattcatcta
     3061 cataggtaac gaattgacct acctcgttaa atccatttgt caaacataac ttagccatat
     3121 aagaatgata atgtttgagt atcatcttga tcgaaattgg atctccttct agagcagata
     3181 agataatgga tagtggaact aataggtact gccgcttttt agatttatct accataggtc
     3241 ataccccatt ttcaattgtt caactgcctt ctttcgttga taccagatac cacttgtgct
     3301 catattgaga attttaccga tttcagcatc attaaaacct gcaaaataat aaagtaggat
     3361 aatctttctt cttatctccg ataactgatc aattgctgct gataactttt gatctgaaat
     3421 taatatttcc attccaaata agaaatagac atcttgttca tcaaaatgag tttgggaata
     3481 cctgccttca tttgaatctg ccaatggttc ctcattatcc tttatgttag cgtttcgttt
     3541 tcgaatagac ttagcttcgt ttcgtaatac ttttttacag taggcatcaa attggtgttg
     3601 tatagatatg tcattgtaat gttgttgcat gataatatgc tcctttttcc ccctttccac
     3661 taatacaaca atcagaaagc cccttttttt cgaaaaaact agaaaaaaaa cataaaaata
     3721 tttatcattc tttaaacaga aaatctttct ataaaaaaca aaaaaaaacg attaggctag
     3781 gctaatcgtt ttttgaacat tcttaaaaaa tccaaattat tttttataac tgaaattggg
     3841 tattgatgac catcgtttct gtagatagta agcaatcatt ttaggttttc tatctctagt
     3901 aaagattcct ttcttatttc cttgcactct taaaatccct tgacttgttg caaaatctgc
     3961 aaaattccac acttgttcac caacaaaatt ttcacatgta tctattactt cgtgatttgc
     4021 ttcgtaataa gccacttgat actcttctgt aaacattgtt ggtactgtat catgaaatcc
     4081 agctactgta tctgctccat attctgtaaa cattattggc gtatcaggac atctttccat
     4141 ccatccatct agctcttttt tcaacagata ttttgcatgt gccagatccc ctcccgaaac
     4201 ataccaacca taataacgat ttaaacataa aacatcgaca atatctccta ccttacaaac
     4261 atctggcgtt gattttagat aagtaacgat tgttacaggt cttttctgcg gatcaagttc
     4321 tttagttaat tcaactaaag gttcaaaata ttctttagca ccttcggaat ccgaatctgg
     4381 ttcatttgca atagaccaca ttacaacact tgggtggttc ttgtcgcgtt ctatcaattc
     4441 cttgatcacc gttttatgag aattttctgt tcgtatctct ttccacgtat tatgtttttc
     4501 cacattatca tctaataaag tggccatgaa atttaaatgt aaccctactg caggtacttc
     4561 atcaataact acaatacctt ctcgatctgc taatcgcata atttcttctg agtaaggata
     4621 atgtgatgtt ctaaaagaat tagcacctat ccatttcatt aaattaaaat ctttaatatt
     4681 tacagcctca ttcaaaccac gtccattaac atacgaatcc tcatgcttac caaatccttt
     4741 aaaataaaaa ggtttattat taatcaaaaa tttgccattg gtaacctgaa cactgcgaat
     4801 accaaattct tctgtatagg tatcgatcac tttattatca tcaattaaac taattttcat
     4861 actatataaa taagcgtcta gaggttccca aaaaattgga ttcttaagct gaatcattcc
     4921 tttctttcct tcagcttcag ctacaagttg agcctcttcg tcatatatcg ctattaagat
     4981 ttttccggtc cattctgtat cgatattgaa ttctacactt gcatccaaat cagttattct
     5041 tgtattaata gtaatatcac ttatatagtc tttcggagtt gtatataact taacaggtct
     5101 atgaatacct gcataattga agaaatcaaa attaactaag ttttcctttt ttatatcccc
     5161 attttcctgt actgtttcct tcataatccc cacaggtaaa gtactatcgt caataatatt
     5221 gtttacagca actgtaattc gattattccc gtcttttaca aaccgattaa tttcagactc
     5281 aaatggtgta aacccacctt tgtgttgagt aataaacttt ccattcaaaa aaacttttgc
     5341 ttcatgtgtt gcagatccaa aacgaagaac taatctttct tctaataatc ttttaggaag
     5401 agtcacttct ttttcatacc acacccatcc aacatgattt ctaatgttct ctgtttcaaa
     5461 taaatcatta taagaagagg gaactgaaat cggataactc tctttttcat ttattggttc
     5521 taaagcaagt tcttcctgta agtcatcatt tgtatctaat ttaaatctcc agagaccgct
     5581 taagtcaatt acttgcctcg tctctgtcat aatgggatac aacatataaa ccactcctat
     5641 ctaaatatta aataaatgta tcctttaaac cacaataagc atctattgga cttactccct
     5701 taaattcaga aagacccatt agtttgtcca ccaatatttc taaagtttct tgttttccat
     5761 cataagtatt aatataagtc tttacttgag gtacatcagc caaatgaaac ggacactgta
     5821 cagatacaaa aattgttgga atttcatgaa tgtaaaacgg tatatccgga gttcctttac
     5881 ttgctggcca gacaattcgt tgaactgtgc ctggattaac attagctata ttaatgatca
     5941 agtcatattt tttagttaaa tttttaattg gtctcttagc agcatatatt ccagctatat
     6001 ttttaatttt ttcttcttgc gataatcctt tcaattcttc ttcaggtgaa atgtattttt
     6061 caacttcaaa tccttttgct gacaaaatct gtttcaataa atcaatggct tgaggtctat
     6121 ttccagcaac tacttcacca aacccacctt ttaccccatg tacatctact agtaaaatcc
     6181 ttttatattt ttctggtaca ataggccaaa tatcttgttt atctttaact aatgtaattg
     6241 cttggtcagc cacctcttta aaaattgatt tattttcaat taaaccaatt ttttccagag
     6301 cttcttgctt aggtaataaa atttgttctt ttgctttttt gtgtaatccc aatttagctt
     6361 ttaaccctaa aattcttttt aaggcatcta ataaccgatc atcagtgata attcctttac
     6421 gatagccttc catcatataa ttaaagtctt catctggatc attaaaaaat agaaatagat
     6481 cacatccagc tgcaatagaa gtgggcaata attctgatcg tttcattgcc ccagtcattc
     6541 ctaacatatg actagcatca gtaactacta atccattaaa tccgagtttt cctctaagta
     6601 agtcagtgat taattctttt gataaagttg caggaagtaa atcttcatct ttcagatcag
     6661 gattaaaatg ttttgaataa gctggcatat ggatatgacc tgccataatt gaaggtaatc
     6721 cagcttctat taagcctgag tatacttttc caaaagaatt atcccattct tccgtaccta
     6781 aactattaat actaaaagat agatgctgat ctcgttcgtc aataccgtca ccagggaaat
     6841 gtttagctgc aggcaaaatt ccactctcct gaataccttt catataagct aaactaagtt
     6901 ctaaaacttt atcagggttt tgtccaaaag atcgactaga aatgatagga tttctccaat
     6961 ttctattaat atctacaata ggagcaaaac tccagttaca tccaatagcc gatgcttcaa
     7021 tcccagaaac tctccctaat tcataagcat atttcgcatc atttgttgca ccaattttta
     7081 cttctacacc aacttcagta ccatctgtac aagctccgtt accacctgct tccgtattag
     7141 cagcaattaa tagaggaatt ttactttctg tttgtaagat atagttttga tcatatacct
     7201 catcagcagt tcctggatta tatcgtacag ctccaatatg gtactgattg accatattac
     7261 tcaagtaatt tttatcacga ctagatccca tattaacaaa caattgacct attttttctt
     7321 ccaaagtcat agaatcaatc gtctcttcaa tccaagaaat agcatcttca tctaaattat
     7381 atggtttttt tcgtaaatct acttttatag tcattttctt tctcctctac ttattagtaa
     7441 gatttttcca aaaagtatct atatattttt gttcaatatc tacataatct cccgataaac
     7501 atttaaataa aacatcagtt cttaagtttt cccatgattc tttttcttta ttgaccaaaa
     7561 taggataaaa gaaaacttta tttttatttg cagcttctag atcaccagga gaatcaccaa
     7621 tcattaatat cttatccaaa tcacaaccat tttcaattac acttcgaata atatcttctt
     7681 tttttccttt atcttgacaa cacagttcat caactaatga taataattca tgtctttccc
     7741 attcttcttg aacagcttcc ttattagctg agcttacaat aattatcttc ccatattttt
     7801 tcagagcttt tatagtatct ctagcactta aaaagggttt atctaatcct tttgcttgac
     7861 taatctgttg attgacttct tccgaccatt ttaaagcttt taataaatcc tctgactgag
     7921 aatattctat ttccctcttc aaagatggat tagacaattc ttttgttaga gatacccagt
     7981 gctttaatcg attaatcgat gttacatcat ttttttctaa tgttttaact aaacctaaaa
     8041 atctgtttat tccacgagtc tctgaatata aattaatatt attccaatcc tgtaggaatt
     8101 tttctctatg atgaacatca aaaatctctg cagcaattgg tccgaaaaag agattgtgtt
     8161 tataagtcat cgtatccata acacagccat ctgaatcaat acaaaatatc caattattca
     8221 tatttctctc ctatttatgt ttttgtttta aaagctcgca attttctaag actttatctt
     8281 tagataatgg ataaaggaaa aataaaatta atcctacaat cagaaaacaa attgatggaa
     8341 ttaatgttga agcgttatat aacttttcta aaacatctcc cgtttgtaca tttgctaaag
     8401 agtcatagcc tataatagaa agagtccaac ctccgacgcc tccagctaga gcttgaccta
     8461 tttttctagc aaaagaatat accgcatata cggtcccatc ttctctttga tcagacttta
     8521 cttcttgatc atcaataaca tcagtaatat ttgcccaaat aacagtatta aacacaccca
     8581 aacccatata gccaaccgaa ctaagaatta agaatacata catattacta gcttttatca
     8641 aaaataagat caaatatact attgctgaaa agaacattcc tactgatgcc agttcttttt
     8701 ttccatattt tttacttaaa aacaaagtta aaggcgaaac aactattaaa accaaaatag
     8761 gattgataaa attcattaaa actattccct gtgcatcatt atagtaatca ggaaatacat
     8821 aattattcat actcataatt aataattgag caaggagtaa gaaaatagcc gcaccaatta
     8881 tagaaagtaa tgccctattt ttaactaacc cttttaaaga ttttaacaat gaaactttgt
     8941 attgagattg gtcaattctt actcgttcag tagttagttt ataacatatt aaataacaaa
     9001 taagtgcaca tatcgaaaat attcccgcaa caattgtaaa agttgatcca ccacgaacta
     9061 tttgagcgcc tgaatcatct cttgtataaa taaataatgg tgttaataca ccaatgacca
     9121 aacttgctaa agtagctcca acatttcgga atgtcgatag cattgttctt tcttctgtaa
     9181 tagaagtaat agctgatgcc attgatccat aaggaatatt tatagatgtg taaaaaatac
     9241 tcccccataa tatatacgta acatacatgt atactacctt aacgctcata gaagctgaaa
     9301 tcatagaagt ttgatacatt aaaaaacttg ctaaagcgac tggaccactc attcttaaaa
     9361 tccacggttt aaacttaccc tgcttagttg ctttcgatct atcaacaata cgccccatag
     9421 ttacatcagt aactgcatcg ataaatcttg ctactaaaaa taatgttcca acggcagctc
     9481 cgcttatccc caatactttt gtataaaaga tcattaaaaa agaactagca aaaatgaaag
     9541 taaaatcgtt tccaaaatct ccaaacatat atcctatttt gtctcttata ccaaattttc
     9601 tttccataca attctctccc ttctgttgtt aagcgttttc attctgatga aagtacgtac
     9661 tatactctga agcgtaaaga gtcagtattt attttttaca tttcagagta ttatttgttt
     9721 tttctcctaa taattcttta tctcataaaa cttatctata tatttactag ctactcgact
     9781 tacttcttca aaatcacctt tttcaacaga agccaataaa ttcccaccta caccaactgc
     9841 aacaactcct acttcaaacc aatcttctaa gttctctata cttactccgc cagtaggcat
     9901 tatatttacg tgtggtaatg gagcttgata ggcttttaca atggatggac caaaagcaga
     9961 acctgggaat agtttaatga tatctacgcc agcagtaagt gcctccttta tctcagtaat
    10021 tgtcatacaa cctggtaaat aaggaatttg atataaatta caaatctcag ctgtttgtcg
    10081 atcaaaagat ggactaacga tatattctgc cccagccata attgcgatac gagcagtaaa
    10141 cgcatctaaa accgtaccgg ctccgattat tacatctttt tgatcagcat attttttagc
    10201 aatttctttg attatttctt cagcattagg aactgtaaaa gttagttcaa tccctttaat
    10261 tccacccgca ataattgaat ttattgcttt aatggcctca tccttatttt tcccacgtac
    10321 aaccgcaatg actccagccg cttctaactt acttaaaatt tctacttttt tcatatctat
    10381 ctccttcctt tatggataca tactttgtct agctgtacta acttacaaag aataaattta
    10441 agcttttatt tcaagtatta ttttctactt ccgatttcaa aaaaattaaa ataattatac
    10501 gcattacgat aacaaatatt ctccactatc tgactaagat acatttcatc atctggaatt
    10561 cggcctgctt taacccactc gcttagtaat tgacataata ctcgacgaaa atactcatgg
    10621 cgaggatagc ttagaaaact tcgagaatca gtcaacatac ctgtaaaatt cgacaacaaa
    10681 ctttgttgtg ccatcgtagt caactgttga cgcattcctt cagctgtatc attgaaccac
    10741 caagcacatc ccaattggat tttttgaatc ataccccctt ggaagctttg cattgctgtt
    10801 gctagtggaa gccaatcagt tggatttaat gaatataaaa ttgtttttgg taagcaccca
    10861 ctcttttcag cggtatcgaa caatgctaca acattttgtg tcaaactagc ttgatccccc
    10921 atcgaatcac caccgacatc tactccaatt tgttccttta atatacttga attatttctt
    10981 aaagcattta aatgcatttg catcgtccaa ccatatcttg tatactcaga catcaaatgt
    11041 aattgaatac ctgtaacaaa ttgtgcaatt tctgataaat ggaaatccgt ttttcctgct
    11101 aaagctttta ttaacagatt gtcgagtatt ttttcatctg ctatttcata aaaataagta
    11161 ttcaaaccgt gatctgctaa tcgacagcca atttgatgaa aatgatccac tcgttggctc
    11221 aatgcttgct tcaacccatt aaagtctttg attggtatag ccgctgtttg actaagtttt
    11281 aaaatatagt tcgaaaagcc tgatgatttg atactccaga ccttatctgg acggaaagta
    11341 ggtaatacct tgaaagaatt atcctgttta gaaagctcag tatgatacca caagtcatct
    11401 gtaggatcat ccgttgtaca gatggctttc acatccatca tctccaacaa ttctttcggg
    11461 cgataggaat ccgtttgaat tttttcgtta gcacgtcgcc aaatttctgg tgcattcttc
    11521 tcagaaattg tcaaatcaat atcaaagtaa cgttgtaatt ccaaatgaga ccattcaaaa
    11581 ataggattac ctggcgcctt ctccactgtt tttacaaaag ctaaaaattt ttcataatca
    11641 tcacctggac cactgatcaa ctcttcttct ataccattag ctcgcatcaa tcgccattta
    11701 taatgatctc cagctccttt atcatttaac catacctgag tcaaattctt gtattgctta
    11761 ttttctagca aatatgctgg gtctaaatga caatgatagt cgataattgg ttggtgtttt
    11821 gcaaatttat gaaaaagtct tttagctatt tcattctcta ataaaaagtt cttatctaaa
    11881 aacatattta aacactcctt tccttccgtt agtttttaga agagaaaatt tttcctctaa
    11941 ataaactccc ttatataatt atttactcgc ccccttttca agcgcttccc aaataccatt
    12001 taaataaact gcacctagag ctcggtcata taatccataa ccaggtctac cggtttctcc
    12061 ccaaatcatc cgaccatgat ctggacgaat atagccatta aatccattat cgtacattgt
    12121 ttttaatatc ttatacatat ctagagaacc atattctgat ttatgcggcg cttcgtaaaa
    12181 atcgagtcca ttgtcactta aatatttgat attacgaaca tgtgcaaaag gaatccgatc
    12241 ccgttgacaa aattcagata gaatttcata gacatcatta tctggtcgtt ctgcaatact
    12301 tccagtacat aatgtaatac cattagaagg agaatccact acattacaca accaatctaa
    12361 atcgtcacga tttttaacaa tacgaggtaa tccgaaaatg gaatatggtg gatcatctgg
    12421 gtgaactgcc attttaatcc caacttcttc acatgtcggg ataattgctt tgagaaaata
    12481 tgcaaagttc tctcgtaatt tctcttcatc aacttcttta taggcttcta ataattgctt
    12541 aatttgtgat aaccgatgag gttcccaacc cggcaattca aaattattag tagaattttc
    12601 tacttctcta ataatttcct ccggatcagt agggatattt tttgaaatat aggctaacgt
    12661 agaagaccca tcatctaaac gataatccaa atccgatttt acccaatcaa atactggcat
    12721 aaaattataa cagataacct caatcccaaa ttctgccaaa ttgcgaatcg tctgtttata
    12781 attctcaatg tattgatctc gtgttggtaa accaattttg atatcatcat gaacattaac
    12841 actctcaata actttcaagg taagtccatt ggcttcgact tcatctttta aagatttaat
    12901 tcgttctctc ggccaaacct ctccggctgg tatatccatt aatgttccaa caattccttt
    12961 cattgctggg atctgacgaa tttcttgtag tgagattttt tcttcatttg ccccatacca
    13021 tctaaaagtc atttccatag ttactttcct ccaacttctg ttatatattt attgattgtt
    13081 ttacgaactg cttgaggacc tactagcatt tcgcaaaaga ttttttcagt tttctttcct
    13141 accccaactt gatataaatc taaaccaaag atttctttat tttctaaaat ttcctgtacc
    13201 gcacaatgaa tctttgaagg atcttgttca cctaatttca atactgataa tttatcctgc
    13261 aactctacca ataacggatc aggacttggc acaaaatttt ccccttgatc atcgactgcc
    13321 agtaaataac gtaaccaagc agcaatagcg ataggaataa atgttagatt ttctgcattt
    13381 ccgtcttttt cgacatactt tttaattgtt tcaccatagc gaatcgctac tttttgagaa
    13441 gtatctgttg caattcgttg tggtgtatct ggaatatagg gattaggcaa acgtttatta
    13501 attacttcat caataaattg ttttggatca ataatgcctg gattttcaac tactggtaaa
    13561 ccttctaaat aacctattcc tttgattaaa ccaaccaaat catcatcctg catctctgct
    13621 gaaattgatt gatatcctag cagacaacct gttactgcca aagcagtatg aagtggattc
    13681 aagcttgtcg taaccttcat gatgtctgct ttatcaaccg tctctctatc tgtcataatc
    13741 acaccagcct tttccaattt aggccggcca tttggaaaac tatcttcaat aactaaataa
    13801 tgaactacct cagtattagt gaaagcagca atattggtat gtttttttgt gtgaatgata
    13861 tctaaatcct cgagccccat catcaataga tcttccttta cattctctga aggatttggc
    13921 gtaattcgat caatcatact ccaaggaaaa gtcacttttt ctttatcctt taaataagca
    13981 ataaattttt cagaaacata tccttctttt tgccaagctt ctgcaatcgt aaaaatacta
    14041 tcttgaaaac gttgaccatt ctgtgagaaa ttgtcagtag aaaccatcgc aatcggcaac
    14101 tctccagcat taaatctgct atataacaag gatgttacaa tactcatcgt atgttgagga
    14161 ttgctaggtc cagatttgat atcagctttg actaccgaaa agaattgccc tttagaatct
    14221 tttaaactgt aacctttttc agtaatagta aacgttgtaa actgtaattt aggatcttca
    14281 aaatatttaa ccactctttg atagtccgct atattcttcg gattgcaata taaactatca
    14341 gccgttactg ccaaaagtct ttttttgagt tcaccatctc cactcataac aatttccaaa
    14401 atgtcattgt tatagtcatg ataagctttt tccactactt cttcatcaaa tgtttcacac
    14461 acaactactc ctgtttctaa ttcattttga tctgctaagc attgagcaat ttctgcatga
    14521 aatcctcgat aaagatttcc tccaccaaaa tgaagccata ctggatgttg ctggccttct
    14581 tgcttaactt ctttgacatc aaaacacggc agtagaatct gcatttcatt gaattcttcg
    14641 atagaatttt gccaattttt aatcgaaacc ataattaacc tcctcaaact gatatgttag
    14701 ttttgataca ttttatattt taaaacccat tgtaaccgtt gtcaatataa aaagggaata
    14761 aacttgcttt tttctaccat atcagaatga ttgtattttt tattcagaaa aataaaatac
    14821 tccttctttt tggactgatt ttatcgaaac ttattttttc tttttttcat gtattctttt
    14881 atttttataa ctagtgtatt acttcaaaat ttgatattat atggcatgaa cagaattaaa
    14941 atatcagtta aaataaaagt taaggagcat tgtgtatgac aattaaaact agtctccaaa
    15001 atcaagctta ccaatctatt cgccgacaaa ttatctatgc tgacttagaa cctggaaaaa
    15061 aagtatcaga aaaaaaatta gaagaaacac tttctattgg tcgtacacca atacgtgaag
    15121 cactgattca actccgacaa caaggtcttg ttgatacaat tcctcaaagc ggaaattata
    15181 tctcattaat tgatttagat tcggccaaaa atgctcgatt tgtcagagaa catttggaac
    15241 gacaaattat gttagagtgt tgtgccaaaa tgaataacca aaaaaaacgg attttagaaa
    15301 ctataatttc agaacaagaa aaagctgtta gtcaaaaaaa tgctcgtagt ttttttcata
    15361 atgataattt attccataaa gcttgttttg aaattgcaga gcgagaagaa gtatggcaat
    15421 ggttagaaaa taacaataca cacttagaac gatttcgatg gctacgagta aaaacggaag
    15481 gattaaagtg ggaaaaaatt atggaacaac attatcaact atttgaggca ttaacaaaac
    15541 aagatccaga agaagctaac tttctaacat cgttgcatct tcatttaatg cttaatgagc
    15601 aaaatattgt tttagctact catccaaaat atttcaaaaa tatataactt ttaactcttt
    15661 ttaaattaaa tggttgttct gatcagaaaa atatcgcttg ttttcttatt atgtaatata
    15721 tttcataaac tattctgcat aacaactatt gtttgtactt tttacattgg ataactaatt
    15781 atgactgctg ataacttttg atattaaact agtatctcca atacaaataa aaaatagata
    15841 tcttgttcat caaaattagt tcgtggatac ttaccttcat ttacatcatt cagcggtttc
    15901 ccattttctt ttattctatt atttcatttt ctaatagact tggcttcatt tcgcaatact
    15961 ttttttcaat aggcatcaaa ttggtgttgt ttagatattt agttgtagtt ttgtgacatg
    16021 ataagtatgc tcctttttct cttttccact aatacaacga tcaaagggtg cttttttcaa
    16081 aaaactagaa aaatcaaaat aagattcgta ttttgattct atatatcctg tttcaactac
    16141 atcttatatt tcacaataga ataaatagcc ttttgcatag ctgcttaact tataagaaat
    16201 tgcaatttac ttcttcaaag tgaaaacgaa tatgagtaaa ataaaattat tcttcttaca
    16261 gataattaaa aatagcgcgt aacaaaaatc ggcattcaat cacataatta ggattgatgc
    16321 cgattactta tattctacgt atagttttag tattcttatt ttttatcacc agtaaccaat
    16381 tgagaacagc cctaaagcag aatagtcttt tatctcaaaa cgcttaattt caggcttagg
    16441 aatatgaata atcttttgag tatattcttt ctcttttaat cttactgaag aaataccact
    16501 gcctatcttt tttacaaata tttcatttgg tgtacagact aataaaacaa tatttgtaat
    16561 caatccttgc actaaagaat taaaaggaag actatttaaa acagggtgtg cataactata
    16621 acatgtgaag tagttatttt gaactttaac ttttaaaaac tttaaaaata atcttatttg
    16681 ttcttctaaa caatcatcta tactcatata atcactccac taattaatct ccccaaaaag
    16741 acacagcatt aagagatata ccaacacaac agtgcaaata actctacatc ttccttcgca
    16801 accttatttc aataaaccat aaaaattatt ttttaataga aactgaaaat taaaactaga
    16861 aaaagtagtt ttaccgaatg taagagcatc atcaccatca atatagaaat acattctttt
    16921 ccagttacat ttaattttta aacaaaattc tccccaaaaa ggaacttttt ctagtgaaaa
    16981 cttggtaatc tctttgtaat taattcttgt taaagaataa ttaaacactt catttttact
    17041 tgttattttt tcattgacta taactagttc atctggtaaa aaaattaacc aacaaacatc
    17101 gacaaacagt aaatgatata atccatttcc acctccaagc atattcaata ctggtgaaca
    17161 tgccttagaa acacgaatat agttatggtt taaatagata ttttctttaa acattgcttg
    17221 tttaaaagcc atatgctctt gttctaaact tttcataaac ttttactcta atgcacagct
    17281 agcagcagct gctgcaattc ctgctacaat atttacctta gctaactctt tagctgcagc
    17341 ttttcctaat tgtttttctg caatttttaa taataaatcc gcagcttttt caaaattaaa
    17401 agcttttaat gcttcaataa aatctccctg cgtacctata gcccaagcca ctcctcctcc
    17461 aggaagagaa ttaatggcta cacatccagc atatcgtttc caatcaactt tctccattct
    17521 aggaacaata atatgttcat aaaagactct tgctgctctt ccttgttcgt tatcttgact
    17581 gattcgttca cgaatagcac caaaatcctt tatatggtat acaccatgtt cgtctaaaaa
    17641 accaactgta tcaaaataaa aagttaattc atctactaat ttattcttta tttctaaatc
    17701 aactgtattc actttttctg tggcatacac acttgttcca gtactaacaa aagtacttaa
    17761 acctaataag aaaacaccta aaacaccaaa tattttaatt attcttttca taatttctcc
    17821 tccataaaaa ataagttact ttttaaatat cttgtttatg aattcattcc ccaaaggcct
    17881 tttaagattg atacagcagt ccgttcactt cttttagact tgtcatacaa gtcttttaaa
    17941 tgatcccata tcagactagt ttgtctatct agcttcaatc cattaaacgc taatgaacgg
    18001 ttcatttttt ctattacttt agataaagct acagaaattt ttataccttc acaacgcgca
    18061 tcttggattt caataatagt atcatcaatt agtttttgaa tttcttgcct atcaacatat
    18121 tcaatcttag aaagagaatc ttttaaagct actaatgatt caacgatttc ttttttctct
    18181 tcagacattt tcttcctcct tctagtgacc cgtaaagcca tgtagagcag agtccattga
    18241 accagtaatt acactatcta caacgccatt ccaatttact ctacattttc catttttcag
    18301 atttgtcggt ccatacggat agcctttttg acattcaatg ttcggattat accagatagg
    18361 attataccat tcagccgcag aagcagattc agtcgataca aacaatccca caccaacaaa
    18421 tccaatacac atcacactat agccaattag ttttttcatc tcgtatccat ctcctaaaaa
    18481 atagaatagt tcttatagtt attcataaga catatttttt ccgtttttgt tttatccttt
    18541 ctgtcctata acaacttttt tcaagtaaag aatgacatag tttttcttaa aaaaacagtc
    18601 tgtttttttc tatttcttcg gtgtataata aatatgagtg ttcatttttt attttaatac
    18661 gcactccgta cataataaat cttgatcgca tcaatctttt gagcttcttg atctactttc
    18721 aattgaagta atacaaattg agtaacctta ttcattgttt cttctccaaa taacaaatat
    18781 tgatccggat tctctatatc ttgtgtcacc tggtaaagtt tcccagttgt tttcatttgt
    18841 acatgcgggt ctacatcaat actattgtct ttaatacaac gatctgtcat atagtccctc
    18901 acagcttgat tgcgtttata aacatctgtg aaattactcc attttctagc aaaatctttt
    18961 aagaaatttt ttgtcatttc atctatttgc atttgttgcg ctgtctcgtc ttctaatgaa
    19021 ccaatttgac tgttactttc agtactttga agagttccac ttgtttcttt tactgcttcg
    19081 attgtttctt ctgtcgttct caattgtgtt ttttgttttt cagaagaaaa ccaatgacaa
    19141 ccagtaagac ctatcaaaca taaccaacta aatactaaaa ttatcccttt tttcacgttt
    19201 ctagtcactg cctttcttat ttcaccttac gaaccagact acgaattttt gtttgattgt
    19261 acgtgcgttg ataccgagcc ataatccgtc cttgctcggc attctgttcc acactagaga
    19321 aatgttgtcc gccatatgaa acatctgtta taattccggt gtgaccatag attccaggag
    19381 acaatgcacc acctgcttgc caattcacca catctcctgc ttgtaaatca cttggttttg
    19441 ggttcatgat tacttgccaa ccataggttg tccagttata atcttcccct attaacatcg
    19501 caaacatgtg tccagaaccc attaactgtg ggccacctaa ttgagataca taccatgccg
    19561 taccaccata acattcccca ttatttacgg atcgtccaat gatccgatcc aaaaccttcg
    19621 cattgccttt actttttcct gcaataagcg aagttttttt tgttggtagg ctattccaat
    19681 gcttgatcgc aaaagtatca tattccgtta agttatagga cgttatgata ctcattgctc
    19741 ctcgataata cggactccct tcggtaatac ctgctgccgc atagcctcca cgacctagaa
    19801 tcaataaaca acttccagga tctttattgc ccacacattg attaaagttg ctttggctcg
    19861 ccaccataaa gccataatag tcataacaag cttttaagtt cggaaacttc atatagaaac
    19921 caccttcaga accaccaatt ccacgtgcag aaccttgtgg gtagggacaa ccaggaaacc
    19981 aggtaatccc aaaaaagttc gtatcgtttc ttccagattg tgactgtcca taagctgatt
    20041 catagcctaa ttgagaaaga atcacactcg gtaataactg atactttaca gctgcaccaa
    20101 ctgctgcttg cgcatgttca tctgtgattg gaccacgtcc tttaatctct gaaaaaatcg
    20161 gtaatccttc ggtatattcc ccattaaaag cgacagctag acctgtagct tctcctccat
    20221 gctcagaaag ttctcctgaa aaaaagaatg gcaatagaaa aaagggaaga ataaagaaaa
    20281 gaagacaacc tagacaccct ttcttcattt cttcctcatc ctttcttcga taatggtttt
    20341 tggactgttc gtccttttgg taaagtaaaa tcagttcctg gttttgcgtc caaaatcggc
    20401 agtgttttag gatccttttc tattttttcc gattgctctg ttggcttatc taaagaagaa
    20461 aatgcaggtt gtaacgattt tggtgcggaa atcgacggtt tactttcaga cgaacgttgc
    20521 cccggttgtt gcacagaacg atttcctgat agagtggcta ccgacgaatt aggaacagag
    20581 tattggttca ataactgctg cattgctgga taactcccat ttttcgcctg atttttcact
    20641 tggcgaatct gttgtgaaag agaaccagca gctgttaatt gtggcacggg tacttttcca
    20701 gaaggaaacg gaatcgattg accaacaaaa gcgatacctt tatttaacaa tggttttctt
    20761 tgattattcc cttgttgctt actcaattgt gccaatgatt gtacctgttg ttttggtctt
    20821 actgaattca tggacgaatt tggaatcaaa ccatttgaaa gaccagaatt ccactctgtt
    20881 ttcgatttgg tagaagacat ttcaggctct accccatgat aacgaacatg acgaccacta
    20941 taaggcaagg cttgatttga acgcccacct agttcaaagg gattaaccac ttgcctccct
    21001 tttaccgatt cttgtggtgt acgtttttgt tgaaactttt gaaatccatg tatcgctgca
    21061 gaagcgagtg gattcgttgc tcgatacaca ttccctgcta atcctgcacc tttgattgcc
    21121 aaattttgtc cagcagttga tagttgacca ggcagttgtt tcatttgaga caaagaatga
    21181 cttgctatgt ttttcgtgtt gtttatagtt tgatctgcag ctcctaaccc tagtttcttt
    21241 aataaatctt tccgttttac aatgagtaaa attgatagga gtgctttgac aaacatattt
    21301 cctaaaaaac caaaaacagt attcattgga attaaatcgt ctactatgtt atagatcaaa
    21361 aatgccacca aaataatcac actgtaaaaa gatttttgaa acatcaagcc caaaaaggac
    21421 tttaaggtat tcatgagcat ataatcaaat actggaacaa aagaagcgag taatgaaaaa
    21481 ggaatcacaa gtaataaaca caacaccaac atttgaaaga taaaacgaat catgccaatc
    21541 actacaagtg gtaatccaat acttagatta agcaatggca ccatagaacc aacgactgct
    21601 ttataaacag ctttagttgg ttgaatatag acacgataag ccttcttttt ccctctatct
    21661 tctcctgcag cagtggtcac ttttgtctca atatcagata attcttcact tgacgcttcc
    21721 ttggctagaa attcttgtgg ttcaatctct gcttgataca attcttctaa atttgttgtc
    21781 ccataattta acaatatata cggatcaaca acagccgctt tataataaag ttggcgcact
    21841 ttttgaatgg cttccttttg tgtcgttggc actaaaacac cattgacatc ttttgtcgcc
    21901 aattcatcta gactatttgt agcagaaaaa ataaagcctt ctacctccac ggacaaatca
    21961 tttaaccctt tggtaaaagc ttctccttta ctaggtacgt tactaccata gccaaaccaa
    22021 accattgaaa aaatgacaac gaagagaaat cgaataaaca ccatttttgc gtaatgtttc
    22081 cctctaaata tacgaagagt aaatagatat aacacataca agacgacaat ccccgcacca
    22141 ataggatcgt atatttttga ataaatagta tccgaaaaag tgaaaaactg gtgaattaac
    22201 tcgttcattg cagctccttc atagagcttc tcaatgacaa aatcaaggcc ttgccaaatc
    22261 aatttactta aactaaagaa catattcgtc atcattttta gaaaatctgt gccatttgcc
    22321 ccaaataaca ttttgcctaa tgaaaattca ctatcagata aataagaaga aaaggtatca
    22381 atatgaaatt tcccaatctc atagatcgat tgatccacct gcttttctgc cgcatacacc
    22441 aatccaccaa caaaaagcag tccgaatcca atcgttaaaa aaaacaaaac gcaccatttc
    22501 ttttccttat gctttatata agccattgtt tcacctcatt tctattgcat gattaacgta
    22561 tcctgttctt ctacttgaga gtgacttgtt ttttccgttg tttgtaatgc agcggtcatt
    22621 tcttcaaaca aactgtgtac attgagtttt cctacacgtc catagggatc taacatccaa
    22681 cactgtcctt taatcatgtg gctcatttca gctaagttcg cttcatttac ttccaaacgt
    22741 aaatgattca aaatcttttc tcgctcactg tcttcatcaa aagcaaagac gacaccaaaa
    22801 ttcccttttt ctttatctga acctaagtca ccaataaatt gtgtatctaa cactaattga
    22861 ttcatctggg aacgccccac acgtgccatt gctgcaataa tactacgtcc tgcgttcgaa
    22921 ttattaaata cccatgcttc tgtaaaataa atcgctgttt tcttactact atctcgtttt
    22981 ccaaacattt cacaaaaacg acctaaacta atcatcaaac acaaagactt tcgatccgca
    23041 tctgtatata gttctggtcg gacattgtca tttggtaatt tcaaatcttg gatctctaaa
    23101 atcgttgttt tggcattaaa gtctaatccc gggttttctc cataagaaaa tcctaaacgt
    23161 aaaatcgaat cttctaccgt caagcgtaaa aactcaccat attctcgaac ctctttttgt
    23221 tccatttgtt ctaaatagtc gaccacatgc atcaagccaa cttgttgtcc ggcttctttt
    23281 tgaactaaaa cttcttggat tccctttaat accgcccctt ttaaaaggtg attggtacct
    23341 aacggactta actcatcaat catatcctgg gctacttgtt tcgcatctac tcgggataaa
    23401 caaacaattg gatctaatac accataatta cggggatttg tagcatctaa cgtgacataa
    23461 ctcatttttt gcaaatgttc tacaaacaaa gggtaatgtt tctgataata cgggtcttga
    23521 atgagtttcg taaaccattt gcgcttttct cctttgggat ccacaaataa actttgtaca
    23581 ttcataaacg aactatacaa aaagagcaag ccaactaaaa aggtcttccc tttaccggtt
    23641 tttccagtta ctgctacatg aggcgcatca aacaacgcac ctttgattcc ttccgcaatg
    23701 gctagaagat tcaaaaagac aaaacgattt gacgcataaa ttaattcttc taatggtgtt
    23761 ttttctcctc gagaaccacc atcccctaat gtatcttgcc gaccaatata ccagccggat
    23821 tccataccta attctgatac tgctgaaaac aaccattcgc caactgcttc tacagttgtt
    23881 cggtgcttcc aatgtaactg ccgtcccaat ggttgcccta ataaacattt atagaacaat
    23941 tctcgttgat cattttttgc acggtggata tggataatcg tatgaagttg ttgaataacc
    24001 gttgcactat tttgacgaac ttcttcaacc gtttgaccgt atacaataaa acatgcgatc
    24061 caatcgacga caggttgccc attatctact cgttgcttta aatgttttac taatcctcga
    24121 acagttaata agcgttcact aggttcttca tcattttgaa ccaattcctt atgctctgtt
    24181 ttgaaccgtt ccgatagcca attcagtttt aaaccaatac ctccctgtcc tttcaagcgt
    24241 ggatagtgaa ttttcattcg caattctgct gggaaagaaa gatcctgagc aaattgaaat
    24301 agatcacaat ttctcatatt ttcaggtgtt tccccaatag gcaacaatgc taaataacta
    24361 ctccctaact catcttctaa ttgaagaagg cctttatgtt ccttcggtat acgtacatac
    24421 gttccttgat tgtctttcag tacttcccaa ttattttgtt cttctacttt gtgagccatt
    24481 cctcgaatat attgcagacg attgagatac aacagctctt tttttactaa gggacgaata
    24541 gaaaagctat aaagtaattg tgtcacttct tttacataag gatcactttc agaaaacaaa
    24601 gtttccaaat catctacttc taatccaaat aagcgtgcta aacttcctgc taaatctaac
    24661 cagattagat ttattacatc atgaaaactc tccaccgttg ctttttcttt gactttgatt
    24721 cctaaaataa atgaaggacg atagacttga ccttctcgtt ccaacaatgt cactgtttct
    24781 tttgcataat acgcaccaat tgcttgacta tcgggagaaa atccctttcc taatgtgtca
    24841 aacttcgtcc gtaaattcat tgttcgtgga tacatcacca actccacatc ttcataatct
    24901 gctaaaagca acagtaaacg agccatcatt tcttttattt cctgtgtctt ttttggtgtg
    24961 ttttttgaaa ttgttcgtgg aaaaacatga tagtaggccc agatacaatc ctctccattt
    25021 aacaaacaat ttttcttgaa tgcttttact ggttctttta caagcaccaa tgaatttcac
    25081 ctcccaataa aaaaggaaca accagttgat tgtccctttt tctaatcctc taaataaaca
    25141 tacttattca caaaaagtaa ttcttccaat gcattgtttg ataccttgtc ccagttataa
    25201 tacacacaat caccattcat catacgaatc atataacaaa accaatccca taaataaaaa
    25261 tgcacttttt ttccatcagg ttttagtttt gccagtgcta acacacataa ataggggagt
    25321 cctatataaa aaacaactcc tgctggtgga aaaaaagaaa tgacccaacc aataaatgaa
    25381 cgtaaaaata aatattcaaa gattacgacc aacaaaaaag ttgctgcatt gactaatgca
    25441 actggaaatg gaagacgcca attgcttgta atctgttgta cgcgataagg ttccgcataa
    25501 acaatcgaat aatcataagg ttcccaatcc acttcactat cctcctaatc cataaataat
    25561 ttttcaatga ttttaccaaa cgcatcaaat acacgtgttg gatcatttaa gaagaaataa
    25621 actgcggcac ctgctgcgat agatattaat gcatttccta cttttgattt cataaaattt
    25681 cgcaatccca gataaacaac caccattatt aaaaaatagc caccttgcgt taatataaaa
    25741 tctacaattc ccttcagtgt catttccgtt cttctccttt cctatccaac caattatgtg
    25801 ttaatttttc aacataatac tgatttgttt ttttcgtaat gacaatcgtc atttgttctt
    25861 tttgtaaaag tgacgtatca ccatctcgaa agacgaccgt tgcttttaca ataaaaggtt
    25921 ttttcgtttc tttataacgc aatactttca tctctacttg atcaacttta gctgtttgat
    25981 tgagtccttc aggttctttc atcatgtatg acatatcttt tgcattgttt ttcgcatact
    26041 tatctaagaa atcttccaca aatccttcaa catctttcgc ttccgacgca tcaaccgttt
    26101 cgtataatgt gtcatcataa gtaatcattc gttgtttttc tgtattcttt ggtagtgccg
    26161 taaaataagg ataagcaata atacgacagc ccttgtttga aatagaaaag ggaagattga
    26221 gtacttgtgt gattgtcaca cttgtttctt tcttactctc tggattcatc gagcgaatat
    26281 cataagttac tttataacta gcagttggaa tggtttcaat ttcttttaat ccaataaacg
    26341 aagcagcagt taattttcga acacctgaaa cacttcctgg ttcttgaata aagttttgtg
    26401 cataaaactc tttttttaat gtttcttgac gttgttgttc ttgttcatga ttatcgaatg
    26461 tattcatata caaagcaaca aaacgattca taaaggattc aatttcaggt gtgtacgtta
    26521 attctgaccg actttgtact tctttctttt gtaattgttg gatttcatct ttcaaaaacg
    26581 acacttgaac cttcgttttc atggattgaa aaaatgccaa gccccctgaa aaacaaagaa
    26641 ataaaaccaa acaccaaatc catttcactg ctttttttga atggattttc ttttgcttcg
    26701 gtactttctc tgtataaact ttttctttcc gccgtagttg tcgttttttc ataagctact
    26761 ccttctagta tgtttttact agtacgtacg attgacaacg ataagcttgt ttttctgaaa
    26821 aatagtccat tcaattaccc tcattttcta ttccttttct ctttctttta tatccaacaa
    26881 atccagcaat acttgtcaac actcctccta gaacagaaag tgcaacatgt atttcttcac
    26941 cagtctttgg taagactttt gtttttccat ctgctgtttt gatttcaata ttgccacttg
    27001 gaagtttctt tacaggaatc gacaaatcct ttaccaaatt cccttcacta tcttggatta
    27061 atggaatacc atcttttaca ccaacaattg tttgatcacc tgctactttt aatggggtgg
    27121 ttggtgttgg aatatgggtc aattcctcta cattactagt gacaatcggt acactcattc
    27181 cttgagaagt attcgtcgta atttcaccgc ttggggttac cgatactgtg acttcttttg
    27241 ctggaacaat aggtttattt tcttttggaa ttgcttctga tttttcaaca ggttgtttcg
    27301 gttcttcttt ttgttcttca ctggtagacg acatcgttgg ctgttccgta cttgacgaat
    27361 cagtattctt ttcagaagaa ctggttgttc ctgattgttc cggagttgtg actatacttg
    27421 aatccgttgt tgttgaacta tgcacacctt cttcttcgat cgaatcagtc ggtaaagttg
    27481 attcaggaaa ctctggttct ggtgtcactg gctctttttc aggtttctct gactgcaatt
    27541 gttcaggttc tgctggtttt tccgttgttc ctccatttag ctctgtctca acatctggta
    27601 atccttcccc tggcaatgtt tctacaattt ctgacttagg tgtttctaca gtttcatctg
    27661 cataaaccaa tgaactccct aattgaaacg aaaataatga aattcctagt gttgttacga
    27721 ctgctaatgt tgtttttttc atgattattc ctccaatttt ttatgcaatt cgtgttttgt
    27781 tcatagacgc cgcactaata ttatctgaac gataaaagaa ctcccgtccg ttttcttcta
    27841 acccaacata tggattattt ttgaataatt gaatcaatag ttcactggtg ttgtattttg
    27901 gatagtttgc aaaaaaataa tactgtgctt gtcgcccatc cgaaaattca acaagtaatt
    27961 cataacgata ccgcttcaat ccttttcgtt gttttaaagg atctctatac caacttgtcc
    28021 atcgttccat tcgtggatag agatagacac gatacacata gaacaatgcc ataccacata
    28081 ccaccaaaaa taataatcgc cacataaaaa ttcccccttt tcttctacct ttcttgaatc
    28141 atcgaacatt cataccctct atagagattt gaaaaatcca tcatcaattg ttcatataaa
    28201 cgttgttgca aatagcgatt gtttcgaata cataattctt catagccatc aatcacttga
    28261 tcttcttttt catagcatct tgtagctcta tgacgctcag cttgcaagac ataaccaaac
    28321 tctgcaccat atcgttctac tgttaataac tgttgactac gcaataatgc aatataacaa
    28381 tcacaaaaat gttcaaccga catttgattt ttctcacgtt tgtgaaatag gtattcttta
    28441 gaaagcacat tattcgttaa acaatctgat aaatagcgat aatctggcgg tcggttattt
    28501 tcatctgtga atttttccca taataaactg atttttattc gttcagcggc tagatagtct
    28561 tgttcgcgtg gataaaattc atcaatcgca caaagttttt tatcacctga ataaacaaat
    28621 ccatataatg cgaaacgaac tcttcctttt caattggctc tcctaaaaat tccagtgaca
    28681 taccatcttc tccttcctaa aaaaaataaa aaagcagaaa ccgatttggc ttctactttt
    28741 ctttcctttt atagctcttt tttacggaag aatccgcaaa tgacattttt tcaaaaaatc
    28801 aatcggcaca agttcacgaa aacttggagc aattttggat agaatcactt ccccatcttg
    28861 taaaatacaa tcataaaaat catcagttac ttgatactta cgcttcttac aataattgat
    28921 aaaatagtag cgatcatttt ctatttccat tcgttgttct actaagcgca tacgaacatc
    28981 atcatagaaa taagccacaa atcgcccttc aagttcatgt ttttcaatgg gatactcttc
    29041 tggtaacaat ctattttttc gtcgtttata cattgctgga taccttagaa gaagttcatc
    29101 taaacgtctg tcagtatatg gtaactgacg aatcaacgat tctaatcgtt ctttatacag
    29161 atagaataat tggcgcaagc aatagtgtac cgcctctgga ttttctaata ctgttggatc
    29221 acgtgaccaa tacgcaccaa cataaatcat aatttttttc atttagacaa tcacaccagc
    29281 aatactaatg accgatccac aataggtaga acaagtggca tagcgaccaa tttcctctaa
    29341 ttctatctca atctcttcta aagaaagata tgtctgttct tctgttggct ggcgactcat
    29401 ttcccaagtg acagtcacca atgaaatttc ttccataaga ggtttttcgc tgctaagtgc
    29461 tgccacacag ttttcatata tcttcatttt atcgcagcct tttttaaccg ctaaaatcgc
    29521 aggtattggc aatgaaaatc gataaaagcg aatgaattct agccttcctt tccttcggct
    29581 aaattccaac tcttcgagtt cttgttcgta tcccttacga acttctaata agcgtgcaat
    29641 ttcttgccag ttctcttttt cctgataacg tccagctttt accgcttgtt caatataagg
    29701 aactcgaaaa cgaaaataag acaaatcaac catcttttca tttaatgctt cgattgcagc
    29761 ctttaaatcc aacaggcgca gccattctgt tgtcgtatat gcattcatgc aattttccct
    29821 cctgacgttc ccatccattc tagatagttt tgttgctcgt catttagttc ggcattatca
    29881 atcccttctt gtacaaagtc tcttcctaaa atacgatctg cttcttgtaa caactttaat
    29941 gtcggagcta cttgtttcaa aaaccagcgt tctgaacgat ctaatgagaa tttttctggc
    30001 tttactgtaa aatccaattc ttccatcgaa cgaaataatt ttgcccatcg tttatcaaca
    30061 atccgtgcat cactttccag tctatcccaa acaataagtt ttgcattaat taaaccaacg
    30121 ccaatctctc ctaaacgttt cggtgaatca cctaaaataa atgcttctac tgcttgtgtt
    30181 gctttctcat tggctaaccg taactcatat cgattataaa taccatattt cgttaatgct
    30241 tctaattctg aaattttttc tcggttcgca atttcaaaac gtttctcata aaaattaaaa
    30301 aagagaggac tctttcgcga tccaaaatac aaagataatc cttcacttcg aaaatagcca
    30361 tcatctaaaa aacaaccgcc aatattctgg aatctcttaa agtccatttc taataaacct
    30421 gctttttgtt tttctagtaa ttcaaagaga tcgaaatgtt cttccgtttc caatccccaa
    30481 agttcatcta acgcaatatc gaatcggcta cattgcacac gtgtataacc agcttccaac
    30541 tttccttgat ttttccaaat ggaatatagc catgttcgcc aatctgtttg ttgttcacgc
    30601 atgacttcct catattcccg gcaaccttgt cctgaaaatt gcacaagtac attttctgtt
    30661 acagttcgtt ttgaatgcca gaacacccag atattcccac gaacagaaag acagtcaaaa
    30721 agatacaagc ccgttggacg tgtttcaaat tctgtcagat ccattcgtaa tacacgttga
    30781 atcactgttt tgtagtctgt cccaaaaaag gaaagacgca aataatcaat cattgctcga
    30841 agatctattc cgcttttcat atacaatcga aagcgttcct tgattcgttg ttcaaaatcc
    30901 tctgggattt ttcttttccc ttgttccatc tttctaatgt aatcttttga gcagcccatc
    30961 aattgcgcaa atcttgcttg tgatagcggc tttttatctc cacttatatt atgaattgca
    31021 cttaacttct ttctgtagct ttttagctca atcggtgtca ttttctcgct ccttttataa
    31081 aataacaaaa tcgatttttt ttaacccttt agaaacaccg atatatcaac tagtccccct
    31141 cgttttttgg gaaaagtagt acaactgctg accttagata atcacttgat acaaaagggt
    31201 ttataaaact tttttctatg tgttatgtta tttctgcccc ccatattata tatcgggggg
    31261 ctttacacaa agaggccgtg cgcaagcgca cgacctcttt gtgagctgca cacgctgcta
    31321 gcgagtgcgc attataggcc catgcttcgc agccttaatg cgcaccgcca ggcagagtgc
    31381 ggctaccaga ctacgtctag agccctcccg atagataata actacaaaat taaatgatct
    31441 aattttgtta tttcactata tttttcagga gaaaaaacgc gataaattga caaagttaaa
    31501 tcctcttcta aatctactcg ataatgatac aatcgagtca atcgttctat atcttttttc
    31561 gttagcaata cttgattaat aacttttcct gtaaaaacac gttctttgcg caaaaagcgg
    31621 taatcagtta cttgttcaat acgattcaac caatcataaa acgttctgga agaaagagaa
    31681 ggattaatca ttcgtattgc tgtagctact ctataataac aactctctgc catttaactt
    31741 cacctcctta gttgattaca aaatatgcgc atcagaaaaa cttgttcctt ttggatcttt
    31801 tgctaaatac atttggcgct ctagttgttc ttgtaacaac tgattatcat ctcccatcgt
    31861 ttgatcttga ctatcctctt ttactgtaaa atcatagaca atcatttcag taaatttctc
    31921 aaattctttg ataaagtgat aatctttgta aacaaatggc gcaaaaaact ctacaggtac
    31981 atcaaatcct ggaaaagcat atccacgacc aggttgatct ttgttgtaaa atggcttatt
    32041 tttaaaatct tctccaaaag tcattaaata accaatggga gacaatcgac caacagaaat
    32101 acggaatgtt aaattatccc gaacaccact tggaaaatat tctgcatctg gtcgttgcat
    32161 tgctaaaata atgtacatcc ctgcttgacg accctttaat actaatggct gaatcaattt
    32221 atcgactcta tttctcgctt ccatatccaa cgaaccataa aaagctgccc attcatcaaa
    32281 aaagataaaa tgcggtggta acccataata agcataattt ttccctggtt catatttagg
    32341 atctttcatg gttttcatat aggcataccg ttgattcatt tcttttaatg catttcgtaa
    32401 acaaataatc atttcttcat ttattttgta aaacacatgt cctttgaata catcgacgtc
    32461 acctaatgct gctaaatctg ccgcttttcc atcgcaaata tctactgtcc caacacttaa
    32521 acaagcttga attaaagaat acaataaata ggttttccca ccaccgattg caccagcaat
    32581 caacatattt ggtgattgat catataccca atccaaagtt ttcattaaat gaatacgtcc
    32641 attttctgct atacattgat caataggaat ccgaccagaa tctgaaagga atacataatt
    32701 gattcgggct ttttctcgtt cttcacgaat taaatcacgc aaaaatactt cagataacaa
    32761 atgacccatt tttaaaaatc gttcgtgaaa acgcccacca tctaaaggaa aagaaaccac
    32821 taattcttgt ttcttttgat aaaaataaac ttttggtaat ctcatttttt cccttgtttg
    32881 tttctcacta acttgtttct ttgtataaac aaaccgattg tcaattaaca ttcgaacaag
    32941 taactgacgc caataaacag aggcaaaata tccttctttt agtcgcgacc aatgcatcaa
    33001 ccctaaaatt aacccactaa ccagcaacaa atacaacaca atacttattc caggaataag
    33061 atacatttgc caattcgaaa acgtacttaa acgtggataa aatactttcc aactaaacca
    33121 acctaacaga atcaaaaatg gaaacaaaaa gaaaccataa tagcaaaacc ataaataacg
    33181 attgaaatag cgaattcgcc gaccacgata cttgaaaaaa tgagctttca attgtcacat
    33241 tcctcctttc tgtttttact tttcctgtgc taaaaacttt tgacaaaaag caactaatac
    33301 aggaatatca catttagtaa aaaaacataa tcgaaaaaga tttaatcgat ttttataagg
    33361 gtgtgcacac atattacata ttcgtactat acgaatccaa atcacttcct gatgatcttg
    33421 tttccactgg tacggtaatg aaaaacgaac aagatcacgt aaaaacatac actgcccaat
    33481 aaccgcacaa atatatgcat ttgtttgtac aaaaatcgtt ggattgtctc caaaatactc
    33541 aatcaattgt tggatatttt gataacaagc acaatctctc aaagtatttg attggtttta
    33601 tctgaattca aaatctcccc ttccttctat cttagataaa aagaatagga agactccttc
    33661 ctattctttc aaaaaaacct tattttttct ctttttcctt agaatcaaca cttggttgtt
    33721 tttgatctaa acctttttct tgtgattgtt tcatattagg attatttgtt ggagcttcta
    33781 ctttctctaa tcctttcgca taaatcacta aatctgaata ttcacgattg ccatcttgtg
    33841 ctggaatata taccacatga tattctggat caattaattt cacaggatca cgtcgtttaa
    33901 aaccagtcaa atctacatct gctggaaatt taactcgtcg tgcaatcttt ggttcatctg
    33961 gatttccaaa aactaattgt gctcgctgtg atcgaatttc tcccgtataa tcgcctgttt
    34021 cattatcaaa tacacgatca gactcttcta atgcgccaaa gcgtacggct cctaaacaag
    34081 tttcatctaa tgcttctgta atgtcataat tatttggaaa ttttaatccc atcttacaaa
    34141 acctccccaa tttttacacc agttaaaaag acaccaacat cttgatagcc agttgttcga
    34201 cgctctgttt gtcccatatc atttgtttca cgactattca ctcgttcttt acgaaaaaca
    34261 aaataagctt cttcaaatga aatacgcacc tctttttctg gtaatcgtaa tcttttatcc
    34321 tcttcagctg tgagataaac aaaaaaagca ggctgttctt ctcgcgaaca ctctgcttgt
    34381 aattgaacat atcgcccaga cacaccatta atttcctttg gtggattagg ttcccgtgaa
    34441 cccaataaaa atacttgacc taaaaactct ttcttcatac gcaatgcttt ttctgccata
    34501 aagtttttcc tcctcttaaa aaccaaaata aattctaaat atttctacat tacaatcaaa
    34561 caagcggtta aaaatcctaa ccgcttgttc ctcatgacta atctttggct ttacgtactt
    34621 tataaagtgt tatacctaaa gcaatgacta atactactaa tccaagaacc ataagtatac
    34681 tacttgtttg ttcacctgtt tttggcaaca ttggtacaac agtagctggt ttaacccgtt
    34741 gttctggttt cactggttgc ggtggttttg gcgcttccac aatttgaacc gtttgatctt
    34801 tgtttgttag atctacattg tgtttcgcca cttcttcaaa cgtttctttc tcatcttccg
    34861 ttttcgcttg gagccattcc gcaaaactca agccttttcc tgcaagattg cgaccgtcca
    34921 ctaagaattc aaataagaat tccatcattt ctttatcggc cgcaaagact ttttccgcat
    34981 gagtgccttc aaatggtgtg ccgtctggtg ttaagtagcc ttgaacaatt aagcgataga
    35041 tttgaccaat cgcaagaccg tctactttga cccattcaag cacagtttga tttggcaagg
    35101 ccaagatctc ttttccgcca tttttattcg tcgctttcgt cgtaatggtt ggattactga
    35161 ttttgatggt ttggtcattg tcggtaatat ctgcgtgaga agccaataat acgccttctc
    35221 taaacagatc ttcaaagacc acgacttctt tgcctcgcaa cgcacgtgcg tctagaataa
    35281 agtctagatt gactgtacca tccgttgttt ctgccacaaa cgttaaggta cttgtgactt
    35341 cttttccatc tactagcact ggtttttccg ttactttgtc cattagaaca ccgttgactg
    35401 tgtatgtttt tccaacgacc aaatcgtggt atttcacagc gtctgtaatg gtgactttcg
    35461 ttaatggatt aacctctttc aagccagtgg gtttatgtgt agccgttgta cgtacacttg
    35521 ggttagttac tcgtaccgtt tgccctttgt cgttgatgtc tttatggttt gctagttctt
    35581 catcatttct aaaaagactt tcaaacacga cgatttcacg accatttata cctgtcaaat
    35641 caaaggtaaa tggtacgatc accgtttcat tttctgcttt ggcaataaag ccaacactcg
    35701 tttctaccgt atttccatgc acaagcaagg gttcaccggt tgctttatcc attaagatcc
    35761 ctttgaccaa gtatgctttt cctggaagaa tctcggtaat ttcaacggta tcgtttaagg
    35821 taaacaatcc tgttgggtct gcgactgtca atccgtcttc aaagacagcc gtggtatgaa
    35881 cggttggatt attcactttc acactttggg cttcatcgtt gatatccgca tgtgctgcaa
    35941 cttcaatgcc atcacggaaa agtttttcaa aaacaacgat cgtttgacct ttcagaacac
    36001 tagcattaac cacaaattca aggtcttttg tgccattgac tttgtctgca ataaaggcca
    36061 aggtacttgt gatttctttg ccatcttgta aaattggcgc attcgttgcc ttgttcatca
    36121 atactcctga aatggtgtat tcttttccga caaacaagtt ggtataagaa acactgtctt
    36181 taatgacgat cgtttctaat ggatcaacca ctttttcacc atcggcttta tttgacgctt
    36241 gtgtttctag ttttggtgga atcaagtaat tacgtacaga aaccactaac gtttccccat
    36301 catctggcgc attttgtttg aatgcaaccg tgaatgcttg tttatctgta tttggttgga
    36361 aactttctaa tggggcattt tccaagaagt aatagtcatc ggcaactaga cctttcacta
    36421 aaatttcccc gttttgatca gtggtatatt caccaattgc ttgattttta ccgttataca
    36481 aggtaaagtt cacacctgcg agcggcgttt tcttcttgtt ccattcttca tacttgaata
    36541 attttacact tttccgtgct tgacggttcg caaaatggat cactttgatc ggttctgtat
    36601 cattggtaat cgagaacact aatgggtttt gattcaaaac gtaatttacg ggggctttga
    36661 tttcttccaa acgatagcga tcttttccat aagtaagtgt accgttagtt aggaaaaagc
    36721 ctttttcatt ggttttaaag atatccgttg tttctgtatc atttggaatc tccattgtga
    36781 cataacgatt ggctaaagta tcaaaaatct tgaattctgt attagcaagt ggaatcactt
    36841 ttcctgtttc ttgatccact ttcaccactt taagacgttg ttcaattact ttatcttcta
    36901 aaacataatg gaaagtttgc ccattttcag aaattgtgac ttcaagtggt tcaaatagtt
    36961 tatacccttc ttttcctttg gtttcagaaa gaatgtacgt atcaaagaca acggtatttt
    37021 taccaaaagt agcataacca tcattgtctg tcacaacggt tttcaccact ttgccagttg
    37081 tttttgacgt caaagtgatt tcaatgccag ctaattttgg tttgttatct ggattcgttg
    37141 aatcgactaa atctttatta gcaactttca ctaaatcaat ggttcctttg atcacttgat
    37201 cttttgcggt cgcattgaca gtttttccag gttcaacaac aatttcaatt gcttcatcag
    37261 aaagcacata accttttggc gctttgattt cttttaaaac atatttgcca ggatcaagat
    37321 ctttaatttc tgcctgtact ttgccgttaa tttttttcaa ggtaatttct ttaatctttt
    37381 tcccatctgc ttgatacaaa ccatagaccg cattttctaa agaagctgca ccttgtgctt
    37441 tcacaccagt ttccgcatct tctttaaaca cacgaatgtt tccttgtttt agaatttgta
    37501 aattaataac agacgcatta ggttctgttg gatgtaacac accaattgtt tgagctcctg
    37561 gacgacgata ggctaatggc gcaccttgaa ctttaatttt attcaattga atttttgctt
    37621 tatccggtgc ctcttttgtg actgtaatcc atacttcatt gccgtgaata gatacattga
    37681 caccttttgg tttttgaatg tctttcacat atttcaaaaa atcattttta ttctttactt
    37741 tcaacgtttc gccaattttt accgtatgtg tttgattatt aaaagttgct ttttcaccaa
    37801 agttattaat caaacgttga atttctgctt ttcgacgatc ataatcaaca cgtatatttt
    37861 tgattgggat ttttgtgccc aaagcttccc aaatcataaa ttgtgccgca atgtattgtt
    37921 catcggattt gtctttattt gtgacatatc ctaaataaga gatcaagctt gtttttttcc
    37981 gtacatttga atttttcaaa tagtttttca aagcagtagc tgtataaact tgaccttctg
    38041 cggctgagac accaggctca atacaaaacg ccacttgtcc attaatctca aaacgaacca
    38101 tataatttaa agtgaagttt agattgttcg gactagaagt aacaccaata ttttcgcccc
    38161 aatcaatttt ccgaccacct aaaacagctg cattggttgc acggcgaaca cgaaccgaac
    38221 gattggttgg tactgttact aacagtgtag gtgtacctgt ttttggaatg ttctgctctt
    38281 ttttcttttg attttcaata ctagccgtag attctttgtt tggtttcgtt ggttgatttt
    38341 gactagctgc ggttgaagag attgtttttt caacgttttc ctcatttttt ccttctttgt
    38401 cagcagtagc cgctggttgt tccactgttt cttctattcg tttcttttct tccgcttgtt
    38461 tctcagaaga ctctggctgc acagaaggcg ttgcttcggc agctttttct ccttctagag
    38521 tggacgtttc tgaagcaggg gttgtaattg aggcagtttc ttcaactggt tgtgaagtac
    38581 caggactatt ccctgggtgt tgtgtttccc caatcgtctg atcgagagtc gttttggaat
    38641 tgaccgttgg cgcttctgtc acaggggcct gttcaacagt ggcttcacca gctgggaccc
    38701 cggcttctgc tggttggact tctgtcactt cagaagcgac ttgggcaatg gcttccatcg
    38761 taggttgtat agccgtcgtt tcttctgcat gtgcttgagc agttcccacc aagaaacaga
    38821 attgagaaaa agccaccaat gcgagtgctt tcaaccaatt cattttcgtt tttgcataca
    38881 caagaattcc tccttttcct gagaatttta tataataaaa caaaacgccg ttaccaaaag
    38941 tgataacgac gtgaactgtc tcttctattt ttatctggcg ctcttatctg aacacatttc
    39001 atcaatgatt ttaccctccc actataatta cagaacaaaa aaagaacctg cttcgtggaa
    39061 atcaactgtc catttcccaa ttggaatacc agcttttttg gcaacttcac catcaccaaa
    39121 tctcatgcca taccaattac taccttcatc cttaatttct ttccaaccat atgacatagc
    39181 ttcatctaat gaatcaaaaa tcatgacact attgccaatt gttacaggat ctggcttaag
    39241 atcttctgga agagaaatat caatcatacc ataatgatcc gattcctcag tattattgtc
    39301 attactagct actggtttgg ttgttctact ggcttatttt gatacaacaa gtactcttat
    39361 tcttctttta cttctccgtt ttcaatttcc cattcaaacc actccgcaaa gtcttgctta
    39421 aaaccatcta ctcgatacct attttgtaaa taggcatctt ctgacgtcgt aggatctaaa
    39481 taggtaggtt tattctctgg acgagcatag acacctaccc atgtttcgta atctccttca
    39541 aaataactat ctaccaaata gccttttttt ctaagaatct cccgaacttg atttttaatt
    39601 attgatactt gttcaaaacc atcactcatt ctatcacctc aaataactct agattctcat
    39661 aaatattccc gacaatttca atcctatcaa tgatctctaa caaatcgcta cttatgcttc
    39721 cccattcgta taagaatttc ccttccgcaa aataaatttt ccataaactt cttcatgatc
    39781 gtcccaacca atatcactct cgaaaaattc cacgttgttc ttatctttta gctcagtaaa
    39841 tgccataagt tcaacatgtt ttccaacctc gaaacaatca caccacccat caaccgttac
    39901 acgtgtgcct tcaataccta agaaactttg tcctcgtgta ttaaacacta aaactttccg
    39961 cattttttgc tcattaatta atcacgcgcg aaatctagga atcacaactt attcgcttct
    40021 tctttataaa taaaaaaact ccaataatcg gaaattacta tcttttcctc attccttttt
    40081 taaatcttca tacttcttct tatctttgtc ctaacctaat aacacaaatt ttgaagaaaa
    40141 actcagtaaa acctgattct ttttttatct tcacaacaac caactttttc ttcagatcct
    40201 tttactagaa cttgtataca aaaattgttg aatgctgata taatttgcgg ctacttgaaa
    40261 aaacgataga tgtaaaaaga taaatagaat cattttttat tctatatcag tctatgattc
    40321 attgcttatc aatcacccaa cccattcgat gccgtttttt ttagagaaat ttaaaaaaga
    40381 ccgtacgaat ctcgcattat ccgattactt ttccagaaaa gatccccaat tctgtataaa
    40441 taaccctatc ttcttgttgg tttcattttc tcatataaga attcagtcaa tctacccact
    40501 atgaccatta ctacgtccaa cacaactgac atattaacca cgtaagtatt ccctcacaga
    40561 tctccgaatc tccatggtat ggattcccat cctgacgctg cagaggacaa catatttcat
    40621 gtggctctgt acccttttga tttggaaaca ctacaaatca atactcatct ataacttatc
    40681 aagcgaactt tcgctaggct tctagtgatt actaaattgt tggataacat acatagccca
    40741 ttttatctag ctgttattca taacagttag ttcttgtatt acttcttccg cttgtgttgc
    40801 cattgagctt gtcaaaaagt tacttagaaa aaagctgcca gtaaagcaac tttcaacaaa
    40861 ccctttttgt ttcttatcat atcaagaaac ctccttttat aaattttttc tataataaaa
    40921 aacgtcgata acttaataag tatcgacgta aactattttt atatcccgta aatcaaaaat
    40981 tctaaagaaa gatttcctat ataagcatat tggataattc gattagtatt gggtatatct
    41041 ctaccattct catacctatc tatggaccat tttgaaattg aaggagaaaa aagctttcca
    41101 aactcctccc tttctagata ataatctttc ctaattttcc tcatccttaa tcccatacta
    41161 aaagaattta tctttttaaa atcgctaact ctttcatctt ttggaagtat attcttataa
    41221 tcttctccgt acataaggta aggaacagtg accttaccaa gataggcaat attcattagt
    41281 ttttcaatat ctggaatatt aatacctttt tcccatctac ttataacatt tttgcctgta
    41341 tagatggtaa agtttttacc aaatttttca agcgtctctt cccggttctt tcggacttct
    41401 cgtattcttt ttcccataac aattttatcg tcttttgata aactaaatat ctcactatca
    41461 cgattaatct ccttcaaaat ttctttttca ttacttaata gaaaaatatc gatttttttt
    41521 tgcatttctt ttgacggatt tctctttcta tttaacacat aactgagtaa tacttcacta
    41581 attcctatat tatcagctaa ctctttgtta agtaacttat tcatatctct gtatgcaatt
    41641 agtttaccga tgagaatctc aatcttatct tcctcatctt ttattagagt ttctatattc
    41701 agaatcttgc ttagagtatt atctacgtct ttagggattt ttcttgaccc tttttcatat
    41761 ttaactaaag tactttgtga aatacctgct aaatcagcta actttttttg agatagtttt
    41821 ttctcttttc ttagagattt aagaaccctt ccacttgaat tatcaaccat gaaaaaagca
    41881 cctcctatga gatgctttca tcatatactg acagctaaaa atcttcaaga aaaatattcc
    41941 aattttgtta attttagtat cgccgtgata accaaatgac agtttaaaat cttttataca
    42001 gataatcctc agtgttgcat ctactcaaaa aggtttattt aataggtttt tcgattgatt
    42061 ataagttatt tcacactatc ttgctcatcc attttcagaa cggccatgaa ggcttcttgc
    42121 ggaacttcga cggagccgat ttgtttcatc cgcttcttcc cttctttttg tttctctaag
    42181 agtttacgtt tacgagaaac atctccacca taacatttag ccaagacgtt tttacgcaag
    42241 gctttgatgt ctgaacgggc aacgattttt tgtccaatag ctgcttggat tggcacctca
    42301 aattgttggc gtgggattag ttttttcagt ttttcaacga ttgcttttcc acgttcatag
    42361 gcaaagtctc ggtgaacgat aaagcttaat gcatcgactt tttctccatt cagcaagatg
    42421 tccatcttca ctaacttgct tttttgataa ccagacattt cataatccaa tgaggcatag
    42481 cctttcgtgc ttgatttcaa tttgtcgaaa aagtcaaaga caatttcaga aagcggaata
    42541 ttatagacga catttactcg gtaatcatct aaataatcca tcgtaatgaa ttctccccgt
    42601 tttcgttgag aaagttccat tactgcaccg acaaaatcat ttgggaccat gatctgtgct
    42661 ttgacgaatg gttcttctac atcctgaatc gttacaggtt caggaaaatc tgccgggtta
    42721 tctactgtag cagtcgtacc atccgtttta ttaacatggt aaataacgga tggtgcagtc
    42781 gtgatcaatt ctagattgaa ttcccgttcc aagcgttctt ggacgacatc catatgaaga
    42841 agtccgagga atccacagcg gaacccaaaa cctaatgctt gagaggtttc tggttcgaat
    42901 tgtaaagcag catcattcaa ttgcagtttt tctaaagctt cccgcaaatc gttgtaacga
    42961 gaagtatcaa ttggataaag accacaataa accatcggat tcatttttcg gtaacctggt
    43021 aaagcttcag cggcaggatt gtctgctaac gttactgtat cccctactcg tgtatcttgg
    43081 acagttttga tacttgctgt gatataaccg acatcaccga ccatcaaaaa gtctctagca
    43141 actgcttttg gcgagaagac cccgacctct gtaacatcaa atgttttgcc attactcatc
    43201 agtttgattt tgtctccggg tttgaccata ccgtccgtga tccggacatt tagaacaaca
    43261 ccgcggtaac tatcataaat agagtcaaag atcaaagctt ttagcggtgc atctaagtct
    43321 ccacttggtg caggaacata ttccacgatc tgctcgagaa tatcttcaat cccaatccct
    43381 gatttggcac tggctaatac agcttcacta gcatcgattc cgattacgtc ttcgatttct
    43441 tgacggacac gttcgggatc tgctgcgggt aggtcgattt tattgatgac tggcaggatc
    43501 tccaaatcat tgtctaacgc taaataaaca ttggccaatg tttgtgcttc gattccttgt
    43561 gctgcatcga ccactaaaac ggcaccctca caggcagcaa ggcttcgaga gacttcatag
    43621 gtgaagtcga cgtgccctgg ggtgtcaatc aagtgaaaga tatatgtttc tccatttttc
    43681 gctgtgtaat tgagttctac agcatttaat ttaatcgtga ttccacgttc acgttccaaa
    43741 tccatcgagt ctaacagctg atcttgcatt tcgcgagacg tcacagtgtg cgtcatttct
    43801 aaaatacgat cggccaatgt agatttccca tggtcgatat gagcgatgat cgaaaaatta
    43861 cgaatctgct cttggcgttc tttcattttc tttatatcca tagcgtctcc tcttttcata
    43921 taatcagcac tttccattat accaacgaaa agcagtaatt taaagagttt ttaattagtc
    43981 agctatagaa gttttttttg tagaattttg ctatactgtt atcaagctaa taaatggaga
    44041 tgaaaaaatg gatcaaaaag attttagaga aaatcttgaa ttaaaaccgg tcactcaaga
    44101 acatatcgat caattcaatg aattgctttc ctatgtgttc caagtgactg aagcagacat
    44161 cgaggaaagc gggtttgaga ataaacgagc ttttatccgt tccaaaaaac cgattttgga
    44221 agtatcgaaa gtgttcggat ggttccacga aaataaactg atctctcaaa tcgctatcta
    44281 tccttgtgaa gtcaatattc acggtgcacg ttataaaatg ggtggtgtga ctggagttgg
    44341 aacttatcca gaatatgcta accatggatt gatgcaagat ctaattatcg ttgcattgga
    44401 taatatgcgc aagaataagc aatggatctc ttatttgtat ccttacagta tcccctacta
    44461 tcggcgtaaa ggatgggaaa tcatgtctga taaactttcc tttaaaatca gagatacaca
    44521 gctacctaaa caaatcccag taagtggtat ggttgagcga ttaccagttg atcatccaga
    44581 cgtattttcc gtttatgaca aatttgccca acaaaaccat ggtgctttat tccgcagtga
    44641 ttttcattgg gaagagtatt ggcgtttcga aaatgaagat gagcgcacag ccgctgtcta
    44701 ctacgatagc aaccatgaac caagaggtgt tctgttctac tgggtagctg aagaaatatt
    44761 tcacgtaaaa gaaatgttct atcttgatca agaagctcga aatggcttat ggaactttat
    44821 ttccgcacat ttttccatga tctactgggt acatggagat atttataaaa atgagccttt
    44881 agcatttttg attgaagata gtcagatcaa agagcagatc gaaccatatt ttatggctcg
    44941 gatcgttgat gtaaaagaat tccttcaacg gtttccgttt gttggaacag ctgatgcttt
    45001 tcatttcatc attgaagatc ctgtcgctcc ttggaataat ggtgtcttcg ctttaacatg
    45061 ggatgaacag ggacaagtcc gtgtcttaaa tgaacctata ggaaaatccg ttcgactgga
    45121 tatccaaaca ttgacttgct tgatgatgaa ttatcgccgt gcttcttatt tggcaagaat
    45181 cgaacggtta gaaacagatg aagaaacact gaagtcacta gagcgtatca ttccaaacat
    45241 ggaagcttac tttagcgatt atttttgata aaaaggatga tgtttagatg aaaatttatt
    45301 ttgccgcacc aatgtttgct aaaagtgatt tgttatataa ccaacagtta gttaaagaaa
    45361 tcagagagct ctcttctgag ctttcgatct atcttcctca agaaaatgaa gcaatcaatg
    45421 acaaaactgc ttatgcagac agtcgaatga ttgctcttgc tgacacagaa aaagtgttgg
    45481 ctagtgattt aatgattgct ttactagatg ggctgacgat cgatgccggg gtagcatcgg
    45541 aaatcggtgt ggcttatgcg aaaggcatcc cagtgatcgg cttatatact gatactcgac
    45601 agcaaggcgg aacccacccg aaaaaaatcg ctgcactaca agaaacagct gaaaatcaat
    45661 ttcactacct gaacttatat acaataggtt tgatcaaatt gaacggaaaa gtggtttctt
    45721 cagaaattga gttgctttca gaagtaaaaa gatttttaga tggagggact ttcagtgatt
    45781 aaagaaatca aaaaggtgca aatagcttta cttgcttttg gtgtattcgt tgtctgctat
    45841 aatttttatg aatttatcac acaaaaatat tcgacttctc aaggaatcac atttatcgtg
    45901 gaatctttat tagggattgc attgattttc atgccacaag tcattttgaa agttttcaaa
    45961 cttaaaatac cagcagcaat cgttttgttt tactggtttt tcttgttcat ctctgtcttt
    46021 ttaggcacag ggatgcattt gatcagtatc atctcttttt gggacaaaat cttacatgcg
    46081 gtgagtccaa tggtcctgac agctcttggc tatggattga ttggttactt gatgaaagat
    46141 gctgagatat caaaaaccag tccttggttg ttcctcttat tcggctttgc gtttgctgga
    46201 ctttgcggcg tgttttggga gttctgggaa ttcttatgcg accagttctt aggcatgaat
    46261 cttcaacgtt ttgctgcttc tgatggcaca ctgtttgtcg gacgagcagc attgatggat
    46321 acgatgggcg acttgctgac aaatacgata ggtgctgcct taatgggatt gtttgcatgg
    46381 tctcaaagta aaaaagatga gcgttacttt gaaagttata aattagaaaa agtgaaaaat
    46441 acctaataaa agaggttgtg acagaagcgg gcagcttcaa gaaatttcgg cttatttttc
    46501 gaagaaacta cttctggaac actgtttatt tgaaaaaagg aggtctgaca ctagttgtgt
    46561 cagacccctt ttttctttta tagtctcaat ggaagattag acgatttctt ctagctcttc
    46621 tgttttgaaa tgaagttgtc catcaagtaa agtaatcgtt acttttgatt taggcataac
    46681 atgtcctgca acgatttctt tagctagtgg tgtttctact tccttagtga taaatcgttt
    46741 caatggtctt gcaccatatg ctggttcata agcattttca gcaatccacg ttttggcttc
    46801 atcactgatt gtcagcagga tttcttgatg ttccagacgt tgtgccaatt gcgccaccat
    46861 tttgtcaacg attcctttca cgttgtctag gctcaatggt gtaaataaaa tcgtgtcgtc
    46921 gattcggttc aagaattctg gtttgaagtt tccacgtaat agcgtgttga cttgttcagc
    46981 cactgcttct ggaatcgttc catcagcagt cacgccttcc agcagtaact gtgaaccgat
    47041 attgctggtc atgatcagaa ccgtattttt gaaatctact actcgccctt ttgaatcagt
    47101 caagcgtccg tcatctagga cttgtaacaa gatattgaag acatcgggat gcgctttttc
    47161 gatttcatcc aacaagacga ttgtataagg atttcgtctg acagcttccg ttaattgacc
    47221 accttcttcg taacctacat agcctggagg agctccgact agacgagaca cagcatgttt
    47281 ttccatatat tcactcatat cgatccgtac catatgatct tctgagtcaa acaagttctc
    47341 agctaacgct ttcgctaatt cggtttttcc gacaccagtt ggtcctagga aaaggaaaga
    47401 acctagagga cgatttgggt cttgcaatcc agcccgtgaa cgaattaccg cgtcactgac
    47461 cgcatcaact gcttcatctt gaccaatcac tcgtttatga agtgtttcat tcaatttaat
    47521 tagtttttct cgttcacctt ctacaagttt cgttacgggg atacccgtta atctgccaac
    47581 gacttgagca atctcatttt cggtaacgga ctcttgaacc atcttaatct cgctgtcttt
    47641 tgctttagct tctaattcct tcaattcttt ttctaattga ggtatcgtac catgacgcaa
    47701 tacagcagcg cgttctaaat catagttatt ttctgcatct tctaattcgt gttttgcttt
    47761 atcgatttca gcacgttttg ctgaaacaga attgacttct tctttttctg tttcccactg
    47821 catcttcatc gcatttgctt cttcacgaag ttcagctaat tcttcttgca aatttttcaa
    47881 gcgtttttta cttgcatcat ctgattcttt tttcagtgca gcttcttcga tttccaactg
    47941 catcaaacgt ctagtaactt gatctaattc cgttggcata gagttcattt ctacccgaat
    48001 cgttgcactg gcttcatcga tcaaatcgat tgctttgtcc ggtaagaacc gatcagtaat
    48061 ataacggtca gataaagtag ctgctgctac taatgcgttg tcatggatgt taacaccatg
    48121 gtggatctca aaacgttctt ttaatccacg cagaatactg atcgtatctt ccactgttgg
    48181 ttctttgact aatacctttt gaaagcgacg ttccaacgct ttgtcttttt ccatatattg
    48241 acggtactca tctaaagttg tggcaccgat caaatgtaat tcaccgcgag caagcattgg
    48301 tttcaacaga tttccggcat ccatacttcc ttctgttttt cctgccccta cgatattgtg
    48361 gatttcatcg atgaacaaga ggatacgtcc atcacttttt ttgacttctt tcaagactgc
    48421 ttttagtctt tcttcaaatt caccacggaa ttttgctcca gcgatcaatg cacccatatc
    48481 taatgaaaaa atcgttttat cttttaaatt ttcaggcaca tctttgcgta cgatacgttg
    48541 agcaagccct tcaacgattg ccgttttccc tacaccgggt tctcctatca gaacaggatt
    48601 attttttgtt tttcgtgaaa gaatacggat gacatcacgg atttcttcat cacgaccgat
    48661 gattggatcc atttttccgc ttttgacttg ctgtactaaa tcaacgccgt atttttctaa
    48721 tgctttgtat tgttcttctt ggttttgtga ggtcactctt tctcctcctc tcatctcttc
    48781 gatgttttta cgcaattctt tttcagataa tccgttttta ttcaaataaa cagttaacgg
    48841 ataatttttt aatttcatca acgctaaaat aacgacttcc gttgaaagaa actcgtcgcc
    48901 gaagctttca cgtatttggt ctgcttcatt caataatcga aagaaattct ggctgaggtt
    48961 ttgtccatat tggacgtttc caccagaaac aactggatac tcatccagta gacgatcaat
    49021 ttcatgttca aaagattcga catccaatcc ggcatccgta tagaaatttc gaccaaaatg
    49081 attagattgt aaaaagattt tccatacatg ggcaatgtcg atatcttgat gttttcgagt
    49141 gaccgcaatc tgttgagctt cagcaatcgc ttcttgaagc gtcgtagtca ttttctcaat
    49201 attcatacag gtataccctc ctaattaaag gtaagatcac ttatttcttt gatctttaca
    49261 aaaactatta tatcgctttg gtcaattttg gtcaaaatat acacatagtt ttttgacttt
    49321 ttttctcgac ttatataaat cttaaaaaaa caaaattgat tgtatgtata taaaaaaaga
    49381 gccaaacaaa cgtaaaatta tcttatccat aacgtttttc tttgatttga taaaaagggt
    49441 agatcttata aaagacctac ccttgatttt ctttattctc tttttttact tctattattt
    49501 cttctttgat cactcttcgc cgttcagcaa tcacatacac aaatccatag agaaatggca
    49561 agataaagga actgaaacga tacagtaaaa gcgaagaaac tgcgtcaact gttccaacaa
    49621 ctggtctgaa taataacaaa tagacaaatt caaaggaacc aataccagca ggcgtaggaa
    49681 taacccctga aagcactact gcaaagctga taaacgaaat ggtcagtaga aaatctattt
    49741 taggatggtt ttcaatcaga atcaaataag gaagtacata ccaaaataca agttttaaca
    49801 tattccatag ataaatccgc aatagcgcag tcctgtcttg gataatggtt tggaccgttt
    49861 cccttaaaga gtagatctgc tgattgcatg tatccaccca tttccgcaaa cgctcacttt
    49921 taaataactt attcgataag ctgacaaaaa atatttgaac attcaagctg acggacatcg
    49981 ccaataaaaa ggcaacaatc acgatcgtca aaaggatacc agcgatgata aaccagatca
    50041 ttgatggacc attagaataa aaaagagaga attggatgac caagccagct aatgcataag
    50101 tgatcactgc cagtttgtac ataatcatat ggagtgctgt cacccctgct ccctgggata
    50161 gcttcattcc ttttttgtta taaaaataaa tctccgagat cagcgttcct gtaccaaacg
    50221 aaacgattcg gtaaaacgca atatagctag aggtcaagaa cccatctttc gttgtaaaat
    50281 tcggcgcgaa aggttcagca atttctttga ttgagcgccc ttcagcgatt tggtaaactg
    50341 tccctaatat aacagccgct gccaaaacaa caacactggt agacagcaat tcggcaaaga
    50401 tatctgcaaa tgattgattg attaaataat aaataatggc aaaaatcaca atcagcaaaa
    50461 gcagattcag aatgatttta gttttcgttc ctttagacga catctcctgc tccttaatgg
    50521 aaaaaataaa tgagaatcaa atcaacaagt acacctgcag cgaatcctat agtaaacttc
    50581 tttttccgag ttttatgatg gaaaactttt cgagagatca atcctcccaa accaccgcct
    50641 aacaggctga caaatatcaa attattctca ggaacacgcc agccgctagt tctagcctga
    50701 tgtttatcat accccatcag acaaaataag taaaaattca caatgaaaag gtaaaaccac
    50761 aaaggattgt gtaacaatac atccattact cttcttccaa ctttctgtta actactattt
    50821 ctaagctttt tcttctttct ttggtgaata aactgttaat ccttttgata caacagataa
    50881 ttcaactgga agatcatctg tcgtgtctcc atccgttcga gtgcccacag atttttcctg
    50941 cgcttggatt ttcatgcgtt tggctgtgaa ataagtaatg ccggggatcg tatagaattt
    51001 gcctctcatg attctaggca aataaaaaat aaatcggaaa atatctaagg aaggtacgat
    51061 cgttacatga aattttccat catctagggt cgctgagtcg tcaaaatttg taaaaccgcc
    51121 cacggagtta gacatcgtga ctgtcaacag ttgggatttt cctttccaat gctcctcgtc
    51181 tgtttctaaa tccaaatgat attttttctt cttcagcaat aacttaaaaa acttcttgat
    51241 aaagatccac gagccgtaac gctgtttttc ttcttgactg atccaaactg ctgtatctgc
    51301 taagattccg attgtcagtg tagagataat gacttcatca ttgacttgac catagtctat
    51361 tttccgtaca ttgccttcca ggatcacgtc agcagcttct tcttttttga ggggaatctc
    51421 aagaacacgt gcaaggttgt tgacagttcc acctggaagt aatccgacat ggtattgaga
    51481 taatgttttt tggaacgctt ggacgatatg atgaatcgtg ccgtctccac ctataattac
    51541 taaagtatca gcttctatgg cttctgcttt cttgactaat tccgcatcat caatcgatgg
    51601 gccagtttca gctagttcta catataattc tggctgcttt tcttttacat aatcttgaaa
    51661 ccagcgtgct aatttctcac cctcatcttt ccctgaactt ttgttataaa aaactagcag
    51721 cttttccatt ctttacctcc tatttactct tcaaaaaaga gggcgggaca accaattcca
    51781 ttgtcctgcc ctttagcctt agacagatga cattccatca ttgggacgaa cgccttgtca
    51841 taagctgttc tttttcgatt ttaactcttt gtgttcaatt ctgcaatttt tacaatcacg
    51901 tctgttgctt tttccattac ttgtaaagaa acaaattcga atcgtccgtg catattttct
    51961 cctccggcaa atagatttgg cgtcggaata cccatgtaag agatttttga accatctgtt
    52021 cctccacgaa ctggttcgat cactggagag ataccaagct cgatcattgc ttgtttcgct
    52081 aattccacga tgctcatatc tttttcaatg atttctttca tgttgtaata ttgatcatac
    52141 atatctactt tgattcgttc ttgatcaaat cgctgattca actcttcttg gatatgtgtg
    52201 atttgtgctt tgcgtgcttc gaatttttca cgatcatgat cgcgaatgat ataactcata
    52261 gaagcttctt caggattccc atccaatgcc atcaaatgga agaaaccttc gtatccttcc
    52321 gttttttctg gaacttcatc ggctggaagc tgattatgaa aatcgattgc taactgtaga
    52381 gcattgatca ttgtatcttt tgccgtccct ggatgtacat ttttcccttg gatcgtaata
    52441 tttgcttgag cagcactaaa cgtttcatac tgcaactcac ctaaaggacc accatcgact
    52501 gtataagcaa aatctacatc gaattgctca acatcgaatt tatccgctcc gacaccgatt
    52561 tcttcatcag gaccaaaagc cactttgatg gtaccgtgag ggatagaagg attattgatc
    52621 aagatctcca ttgcagtcat gatttccgca atccctgatt tgtcatctgc tcccagtaat
    52681 gtactgccat ctgttgtgat caatgtgtgg ccttcataat ttttcaaatt tggaaaatct
    52741 tttgtattca atgtatagcg ttcttccgca tctagtacga tcgtagactc gccatcatag
    52801 ttttcaatga tttgtggatt gactcctact gcattaaaat ctgctgtatc catgtgggaa
    52861 ataaatccaa tggaacgcac ttcatgatca acattgcttg gtaatgttcc cataacgaat
    52921 ccgttatctt cattatagaa aacatcagct aagcctaact cttctaattc ttttttcaat
    52981 tcttgcgcaa aagcaacttg tgtctgagtc gatggagtcg ttttgcttgt tgcatcggag
    53041 cgtgtttctg ttttgacata tcgtaaaaaa cgtggcaaaa gattttcgta catagtattc
    53101 tctcctttta attaaattga aatgggtttg tatttgtttc agaaacgaaa aagttaatat
    53161 cccaattttc ttcttgtttc caagattcaa atttctcgat aaatcgttgc ttgcataacg
    53221 attcaatata atgaccggga tcaattgcaa tcaacccagc gctttgcata tcatgagccg
    53281 tatgataata gatatctccc gtgatataga catctgctct ttgggcgatt gcttgcggat
    53341 aaaatttttc accgcttcca ccgcaaatcg caatgcgctt cacagaggat tttgcatttt
    53401 ttggctggac tattctcagt ccatctagtt ggaacgcttc ttttacttgt tctacaaatg
    53461 cctctataga aatttcttgc ggcaattcac ctactcgtcc taacccaaac atttcgactg
    53521 gttcatctat agcgaaaaga tcataagcag gttcctcata aggatgagct gaccgcatgg
    53581 cttgaatcac ttgtttttcg atagtttccg gcaaaataac ctcaactttt gcctcttgaa
    53641 cttgttctgt cttccctact ttcccaatcg ctggttgtgc accagcttcc ggagtaaatc
    53701 gaccgtgtcc aatcgaggta aaacttgtac cggtataatc accttgtgta ccagcaccag
    53761 ctgcagctaa tacttcacgc attttctgtg catgatccac aggtacataa acggccagtt
    53821 ttttataatg aatctcatga gtctttacta aataactctc cacttcaata ccgagaagtt
    53881 cacaaaacca gtcattcagt ccatcccaaa taatatccat gttcgtgtgt gctgcataga
    53941 cggcaatatc atgtttcaac aaatctgcat acattttttc ttgtggctga tcagtaacca
    54001 gccgttttac aggacgaaag attggaggat gtttagcaat cagcaaatcg atttttttct
    54061 tgattgcttc ttcgaccact tctggacgaa cgtctaatgt catcattact cgttggattg
    54121 gcttatccaa tgttccgata tgcagtccga ctgggtctcc ttcttcagct agccactgag
    54181 gacaatagct ttcaaacttt tggatgaaag tgcgtccgct gattgtcatg gctttaaaac
    54241 ctcctcaatc atttggattt cctgctcgat ttgtttttga cgtgcctctt gattagctgc
    54301 ttgtttgagc tgttcacgga tagcttttct ttgttgaagc tctcttgtcc attttgattt
    54361 gaagatctca cttttctctt caagcagaaa tggcccgaac atcagctcca tttcattgta
    54421 agtaactggt ttttgttctt tttcggctac aatgatttca tatatttttt tattttcttc
    54481 aagtattttt tctgattgga ttttatactg attttcttgc agccaagatc gtaatgtacg
    54541 ctctccgatg tttggctgaa ggatcaaacg ttcttgtccg cttaagcgtt gattcaactt
    54601 gccagcttct aggatatctc ggatcagtga acctcccata cccgcaatcg tgacagctgt
    54661 aataccatct tgtggctgga tagcatctag accatttgca aggcgtacgg tgatacggtc
    54721 ttctaatcca tcttttttga cttgcttacg tgctgattca taaggacctt gaacgacttc
    54781 accagcaact gcatattcga tttttcctct taatatcaat gcaacgggta agtaagcgtg
    54841 atctgatcca atgtctgcta aacgagcgga ttcagggaca aagtcaccca ctgcggctaa
    54901 gcgctgagat aaatctaaat ggttcatagc ttcactcctt ctagataatt atagcatttt
    54961 ccaaataaaa taaggagact aggaataaaa aaattcccat atctccttaa aaaatatacc
    55021 ttttcgttct ataaaacaac attttcttat ttttgaaaaa atgttattgg ttatttgttc
    55081 aatgaaacat caataatcga atctccagga acttgcggtg ggatagacat cgtcatgatc
    55141 ggcatctcaa ctaatgtaaa ttggactttg tcaccgattt tcaattcatt tatgtccacg
    55201 cttatttttt cagcagtagc atttaagatc actccgtcat tgctgaatga cgttcccata
    55261 ttcgctggat cttctttggc catgacatcg acgagtttca actgaagcgt ttcttcttct
    55321 gcttctactt gagtgatact ttcaatcgtt ccgacaaata tgctttgtct ctccgttttc
    55381 gtactgcttg tttttactgt ttgacccgca tcaatcgaat caacagaacc tgtgttgcta
    55441 tctgcgctac cgcagcctgc taaaagaaaa aatagaccaa ctacagatat actagaaaaa
    55501 atagccctca taaaaaatcc tccgtttaag tttctgcatt acttgttgcg gtgattgtct
    55561 ccggtcattt ctgtccatat aatgattcgc tgacctgctt ttactactag gtcaaatgtc
    55621 agttggactt gtcaactgtt caaccattgc gtcggttgcg accagtcatt tcgatttctt
    55681 ttgtcaaata acgtatgcgt tccattatcc gtttcgcttt tagcggctct tcatctccac
    55741 gttgagtgac ggacaaatgc tgttccaatt catccattgt aaaattcgat gagaagaagg
    55801 ttggtaactg ttcctgcatc cgatattgaa ggataacacc gaatacttcg tctcgtatcc
    55861 aactactcat cgcatctgca ccaatgtcat cgatcatcaa aataggtgaa cgtttcactg
    55921 catctaactt ttctgccact tgatcttttc cgattgcctg tttcatctca acggcaaatg
    55981 tcggaaaatg gactagcgtc gtggtgaatc cagcaatcgc taattctctc gctgttgctc
    56041 ctaataaata tgtttttcca ataccaaaac ttcctactag atacagtcct ttatgatacc
    56101 cttttggatc agcagtatat ttctctacaa aatctagggc ttctaagctc gcatatcctc
    56161 gtccatctgt acgttcaaag ttttcaaaag aagccgattg aatatctttt ggcatatcca
    56221 ttgcttttac tcggcttctg atttcttctt gtctttgccg tgctaacaat gcttccgttg
    56281 gtacataagt gacatccaca taatgaaaat tcaacgtcag cttcggctca tagccgggag
    56341 cgatcatcgt tggatcgttt ttttgatatt tacgcttttc ttgcacgaat tcatacaatt
    56401 tagcgtaact tttttcaata tccgcttgtg tcaattcttc ttggtgtgcg cttagaaaag
    56461 cttgaacatc cgcatcattt aagacttcag cgatcatttc agcatacttt tcttgataat
    56521 tgcgtttgct gatgatcctc ttcaattctt tgcctacgtc ttccactaga tatcaccctc
    56581 cttttttgcc aggtattctt taaaacggcg gtcaatctct gcttttttct cgctgctgat
    56641 ctgtttttca tcttttggct ggttgaccca atcaggaagc ttttcccgtc gaacatttcg
    56701 cttgccagtt tgataatttg tttgcttctt ttgttttgat tgttttgctt gattacttat
    56761 ttgccgaatg tgctggatcg cttcttctgc tgtggcgatt ttcttttgtg cccattcatt
    56821 tgccactgta tttacataac tggcatttaa gctagcatta ttcttgatca ctagtacata
    56881 attcagcaaa acattgatca cgctactgga aagacctgat tgagaaacaa gatcttgcag
    56941 taaccagttt tcttgtttag aaacatatcc gcctttttct gacttgattg cttccagata
    57001 tttcatcggt ggaatgctct gtgcttcttt tatcagctga agcgctgcgt ttgtcaaatg
    57061 ttcgtttgac gagggttcat tactgttttc agaaaccgca actgtttctt ttgtttgctt
    57121 caccggacgt ctctgcattg ccaaaatggc tttttgcagt tctttttcag atactttttg
    57181 ttcactaaag tcataagatt gactgatcag ttcgccaagt gtcaattcat cgaaaccgta
    57241 aagctgatga tacatgtcga cttgtttgat gattggatca tcaagacttg caatatgttt
    57301 ttttgccagc caatcattca aaaactgcca atcgaatgtc gaatctgctt caagtaatgc
    57361 tactgattca gattcttcaa aagatttatt cagcgattcg atgttttctt gattagcagc
    57421 gtacactgct tcattgaagc gataaacatc taaaaatttt tttgtgattt tttgatatcc
    57481 ctctgctgta tgccttttag gttcaaagaa ttgggtaagc ttctggaatc gtcgttcacc
    57541 aactttttcc agaagaagaa aagccagaac agagtctttg aaaaatgctt taggaatgag
    57601 tggttctaac agctcataaa taaaacgagg tcccagatca ctatcttctt taaaataaac
    57661 atccagtaag ccgattcctt ctagcttttt tcttgcatca taaaattgcg ggataccgca
    57721 gcctagacta ctaagcagat ctgcatgcat cccttcagga cctttgccag attcttgaga
    57781 gatttctgat aacagggtga aatagatact caaggcttct ccgccgatta gtggctgata
    57841 aagatacagc aaggcgttct tgctgtcttc tctcagcgga gccgcttttc ttccttggta
    57901 aatatttttt ggttgaagct ctttccaagc attttccaag gaaatgcctc ctttttgttt
    57961 cttaattgtt ttctttatta ttctctttat tattttcttt tgctttatcc acgatatctt
    58021 gcaactcttt taagaaaaca gacatatctt tgaactggcg ataaacactt gcaaaacgaa
    58081 tataagcgat ttcgtctaaa tcaactaaat cttccatcac atattcacca attagattcg
    58141 tcgatacttc gttttctccg agactgcgta cgcggttttc gacatggttg acgatttgtt
    58201 ccatttgttc catagctaca ggtctttttt ctgctgaacg gatgagtcct cttaaaattt
    58261 tatcgcgatt gaactcttcg cgttccccgt ttttcttgat tactaataac ggagcagctt
    58321 caattcgttc aaatgtagtg aatcggaacg aacaattctc acattcgcga cggcgacgga
    58381 tcgcacgtcc atcatctgct tgacggctgt cgattactcg tgaattatta tgttgacatc
    58441 tgggacatct cattttgtct cacctcttgc atcgcatttt atataaagga tgtgtctttc
    58501 tttacaacta gttgtattat aacacgaaac aaatcacaaa cgcgactgtc ctacccaaaa
    58561 aacacggata taagaacaat tttttctact ttcatgcgta attgtgtccc ctgtccttac
    58621 taaatttcaa ttttccaata ctgatcacct tgattactga gaaataactt acacaaaagc
    58681 tgatttagtc atctagcaca aaaaacttga agcagatgaa caccttctca tctgcttcaa
    58741 gtcacatctc gattttttac tattttataa cttctcttcg attcctgtat agtgtttcat
    58801 tcgctgttcc tcgatttttt gctcatcggg aatgtggtca ctttctggga gcggtgtttt
    58861 actacgatca ggtgtcggat tttttcgttc ttgagtcaaa tcttgccgct tcgcttcttc
    58921 ttctgcctgc tggtcttcta tttcatcgat tcttgcttgg tactgctttt ctttttcttc
    58981 tgctgtttct gattgcgtac gaccttcatc gattagattt tctttattga gcatctcgcc
    59041 gattttttct tttgcgttac ctacgacttt atccttttga ttttttaatg atcccatcgc
    59101 tatccctcac tttctatata ctcaggatag caaaattgac acagatactc aaagaaagcg
    59161 attagcaaaa agccaatttt cgatttgtcc cacaagtatt tcttttgttc cattgttgtc
    59221 gaacaaaata tccgcacgct gctttttttc ttcgattgga agttgactac taattctctg
    59281 ctgcgcttgt tctagcgtca gttgattacg tttcatcaaa cgctgaagct gagtttctgg
    59341 cgtagtataa acgacagcta ctgcatccat atagtggtca taatgacctt cgtagagcaa
    59401 tgggatatct acaattacta aaggatgatt ggaacttaga gaggcgattt gatcttttat
    59461 cgcttttcgg ataaacggat ctaatagctg atcaagtttt tgccgttttt cctttgatgg
    59521 aaaaacaatc atcccaagtt tccctcgatc tagttgccca tcaggctgca atacctcttg
    59581 gccaaacact gatacaattt tcctcagagc aagcgttcca ggctcaacag tttctctggc
    59641 aatcacatcg ccatcgatca aaggaaatcc atgagactga aagactttgg ctgccgtact
    59701 tttaccggta gctattccac ccgtcaaacc taaaacaaat cctactttgc gatttttagc
    59761 ctttgacaat tcggacaata gtgcgtcccc ctttgtgcca cttttgtttt cacgatcggc
    59821 gttccacaac gtatacatgg tttgccagtt tgctgataga catgcagtgc tacttgaaat
    59881 ccgcctgatt ctcctaatgc attcaaataa ctgcgaatcg tggtacctcc ggcttctatt
    59941 gcacgatcca aaacatcaat gatcgataga cgtaattgtt ctacctcttt ggggcgcagt
    60001 gtgttcgccg gttgttctgg atggatcttc gcttcccata atgcttcatc tacataaata
    60061 ttacctagac cagtcactag acgttggtct agcagcaatg gcttgattgc tttgtgggac
    60121 tttttcagtc catttgcgaa atctgctaat aagaagctat ctggcaaagg ctcaggtccc
    60181 aatttcatga ttcctcggta agttgcactt gctccttttt cgacgattgt catacgacca
    60241 aattttcgta catcgttgta gcgaagttgg cttccatcct caaaaaagaa aagtacatgc
    60301 gtatgtttat cgattggtgt attttctttc gtaaattgat attttccttc cattcgcaag
    60361 tgtgagatca gttcacaatg atcgagatga aaaattaaaa acttccctct acgtccaatg
    60421 gattggatgg tttcgccaac aagagaagcc tcaaagatgg gtgtctctgg ttgctcgatg
    60481 atcttgggcc acaagacctg aactttttga atcgtttttc ctactactaa ccgttccaat
    60541 cctttacgaa cggtttctac ttctggtaat tctggcattt tttcttttca ccttcattat
    60601 attgctctgt cttaaacaat gtttattttg cttcgtacca cgtttttccc caactgctgt
    60661 cagtgatcag tggtacatga agagaaacag cttgttccat aacttccttc accaatttat
    60721 ctaatgattc aagttctttt tccggtacct cgaagacaag ttcatcatga acttgtaaca
    60781 gcatcgtagc ttgaagacct gtttctttta atcgtttatc caattcgatc atcgcgattt
    60841 tcaaaatatc agcagcactt ccttggattg gtgtattgat agctgttcgt tccgcaaaag
    60901 aacggatatt gtaatttctt gaattgatgt ctggcagata tcgacggcgg tgatacagcg
    60961 tttcgacgta gccttggtct tttgcttcgc gtacgattct ttccatatat tctttgacac
    61021 ctgggtattt ttcaaagtac gtatcgatgt attgctgtgc tgcttttcgg ctgattccta
    61081 gattttgtga aagtccgtaa tcagagatgc catacacgat accaaaattc actgcttttg
    61141 cctgcctacg catatttggt gtgacatcct ctgccttttc gattccaaat acacgcatcg
    61201 ctgtgctggc atggatatct tgaccttcta ggaaggcagc tttcaaatgt tcatcatttg
    61261 agatatgcgc aagtacgcgt aactcgattt gtgaatagtc agaagaataa atcagccagt
    61321 ctttttctct aggaacaaat gcctgacgta tctttctccc ttcatctaat cgaatcggga
    61381 tgttctgcaa attaggatca acagagctta atcgtcctgt ttgggtcaat gtctggacat
    61441 aacgggtatg cacttttcca tctgattgga tcactttcag cagtccctcg acataggtag
    61501 attgaatttt tgcaatttga cgataggtga ggatatcctc tacgattggt gcttgttcac
    61561 gaagctgttc cagtacatct acggctgtgg aatatccagt ttttgttttt ttgataacgg
    61621 gtaatcccat tttttcaaat aagatcactc ctaattgctt tggtgaattc aaattgaatt
    61681 cttcgccggc ttcttcgtag attttttgtt cgatctctct taagcgagca gagaactcgc
    61741 ccttcatttc ttgtaagcga gtcgcatcta ctttgatccc gcttatttcc atctctgcca
    61801 aaatgataga caatggcagt tccattttcc ggaaaagatc ttcttggttt ttttctgcca
    61861 gttcttggct caattttggt gtcaacgcat tgattgcagc tacttttcgc gctaaatgag
    61921 caaaaaagag ttcctcttct tctggtaaac cttttttcgc ccctttgccg tatacagctt
    61981 catctgattg gatatcgttg tatccgtaat gagcagctat tccttcgata tctgtgcttt
    62041 tttcattcgt atcgagaagg tatgcaccta gcaagacatc aaaatcgatt cctttcgttt
    62101 ttccagtata gcggtttaaa gcaacataag ttcgtttcgc atcatatact tttttcagcc
    62161 gagtcggatc agtgatccaa gaatggaacg ctcggttttc gaatacagat agatcgttcg
    62221 tgacataaat tttcttttct gtcccccacg ctactccgac gatttcctct gtatgataat
    62281 tgtcgcccat catttccacg tacaacgcca tatccgtagt aaacatttcc tctttgaatt
    62341 catgaacgac ttcaaacaaa atatcatcca tttttacttc ttcttctacg atattcaatt
    62401 tagaaaggaa ctgattgaaa tccatttctt tataaaacgg aacgagttta tcgagatttt
    62461 tcccttcata cttcaatgag tcgatagaga catccacagg cgctgaagta ttgatggtcg
    62521 ccaatttttt cgataagaaa gcctgctctt tgtcatttat cagattttct ttcattttgc
    62581 tttgcttcat ttcatcgata tgttcataaa ttccttcgac tgagccatat tgtttcaata
    62641 gcttgatagc tgttttttca ccgattttag tcacaccggg gatattgtca gaggcatctc
    62701 cggctagtcc cttcatgtca ataatctgtt ttggcgtcaa cccatcatat ttttccgcta
    62761 catgttctgg tgtatagctt tcgatatcgc tgacaccttt tacagtgata tccactttta
    62821 cttctttact agctaattga gtcaaatccc gatcacctga aagcacgacg acatcaaatt
    62881 gatctttgtc tactttttct gccaaagtac cgataatatc atctgcttca taattgggca
    62941 attcgtaata ctgtacccct agtcctgtca acaaatcacg tatatatggc atttgttctt
    63001 tgaattcgcc aggtgttttg gatcttccac ctttgtactc cgcatacatt tctgtccgaa
    63061 aagtcgtttt tcctgcatcg aacgcaacca gaacatgagt cggttgctct ttttgcataa
    63121 cattttcaaa catcgtattg aatgcataga ttgcatttgt atgaagaccg tttctatttt
    63181 tgaaacgttc aagagaattg tgaagcgcaa agaatgcgcg aaaagccaca ctgttcccat
    63241 caacgagtaa taatttattt tttgtcatct tcttaactcc ttactgtaaa gttcttattc
    63301 attctaacaa agaatcctgc ggaatgcgaa aagaaaaagc gggaccatac caaataattc
    63361 ggtatagccc caactgatga atttttttct tttttagttg ttccgtccaa agattctcag
    63421 aaacgccaag aacaagttga taaagtccaa atacagcttc aatgccatga atacagcaat
    63481 tccactatgt gctgttccgt ttgtctggac atagatatta cggatgcttt ggttatcata
    63541 agctgtaatc cctgcaaaga tgacgactaa cagtagggag atgaacagct caactacgct
    63601 acttctcaaa atgaagatgt tcaagactag tgcaatgatc actccgatta aagctgcctg
    63661 tcctgctctt ccaaccccgc taagatctct ttttgttgtt actccgacaa cagacatccc
    63721 catgaacatc aaagtagctg tcaagaaagc ttgcgttact gttccaatat cgtagtatgc
    63781 aagagtaacc gctaatatta tgccattcaa aagagagtag gcaataaatc caccgattgc
    63841 taagctcgga ttcttttgtg cttttacgcc tagaaccatt actaaaatca gttcaacgat
    63901 ccacagaccc acaaagccta gtggaaaatt attgataaaa gttgctaatt gcaaaggaaa
    63961 tacccaaaga gccaagtaag aagtgactgc actaagggca agtcccatac ctaaaaatcc
    64021 ataaactttt gcataaaaac gattgatacc tgacattgat gtacttggat tattcattca
    64081 attcaccttc actttcgatt gctatttcca attcaggaac ttgtggcggt tggaccataa
    64141 cgacagcatc caacacacga tcttcgttcg tattctccgc ttctacagaa atcgtcacca
    64201 catccttcat cttatctact tttatgacct caaactgaaa agtcagtgtt tcataatgga
    64261 aaaccggttc aataaaattg acagaaaaat tgacaacatg tgatcctggt ccaggaagat
    64321 gctttgaaat tgcacttgtg atgatcccca tcagcatcac tgatggaacg attggctgtt
    64381 gatattctgt tttttgtgca aagtcatgtt ggatatacaa aggatttgca tcattcgtca
    64441 atcccaaata cagcaaaagc tggttatctt caatagattc tgttaaggat aacgagtcgc
    64501 cttcctcgat ttcatttatt gtttttccta gttttctcgg cttacctatg ttcaagatag
    64561 aaaccctcca gtttattttt aatcatacat tattgtacca aaagtagcgt aaaaggcaag
    64621 ttctgctccc ttgatttaac agattcctat agtttacaga ggtcgtgaaa aagctgtcct
    64681 gcatcaaata ataagaacag ccaagaaaaa acagcttctc atgtttttga tttgattggg
    64741 cttattaccg cagatgcaag cttttgaaca ccgtttatca taagttgcaa aaaagggggc
    64801 ttggcaagat ttttgccact ccccctcttt ctatttttat aaggacactg cagtaattgt
    64861 attacagtac atttttcgtc gtgctgctta aaagtttttc atacgcttgt tcaaattttt
    64921 gaacatctcc agcacccatg aagattacta ctgcatcatg ataatctaac aatggagata
    64981 cattattttc tttgatgact tctccacctt ttttgatttt cgctccaagg tcttcaatct
    65041 taacgtttcc ttgttcttcc cgagccgaac caaaaatatc gcataagtaa actttatcag
    65101 ctaaatcaag tgcttctgca aattcatcca tcaatgcaat cgtacgcgta aacgtatggg
    65161 gttggaaaac tgcaattatt tctttatctg gatatttttg gcgtgcgcca tcaatcgttg
    65221 ctttgatctc tgcagggtga tgcgcataat catcgactac ggtcatgtct gctacgatct
    65281 tttcactgaa tcgacgtttt actcctggga aagtcagcat ttcttctgca acttctttca
    65341 gatccagttt ttcgaaataa gctactgcaa taacacctaa agcatttaag atattgtgtt
    65401 taccgaatgc tggtacagtg aagtgcccaa caaattcatc cccatgatag acatcaaaag
    65461 cagaaccaga agttgtgcgt tcgatgtttc gtgcttggat atcatcgttt tctgtgacac
    65521 cataataata aatcggcaca tttgctttta atttgcgtaa ataagcatcg tcaccatacg
    65581 caaaaatagc ttttttcact tgtccagcca ttgtttggaa agctgtaaat acatcgtcga
    65641 tacttgtata ataatccgga tgatcaaaat cgatattggt catgattgca tagtctggtg
    65701 aataggcaag gaaatgacgg cgatattcac aggcctcaaa tgaaaagaat tccgcttgcg
    65761 gatcaccatg tcctgttcca tctccaatta gataacttgt tggacggaca ccactcaata
    65821 catgagagag cagtccagtc gtacttgttt ttccgtgaga gcctgttaca gcgatactcg
    65881 tataattttg gataaaatga ccaataaagt cgtgatagcg aatcacttcc aaacctaatt
    65941 cttttgctcg ctggatttct tcatgtgaat caggaaatgc atttcctgca atgatcgtca
    66001 tccctggttt tacattatct gcgttaaatg gcagaatcgt gatatttgct ttttctaaat
    66061 ctctttgtgt aaagaaatat ttttcaatgt ctgatccttg gacatttaga ccttgttcat
    66121 gtaaaacaag agccaaggag ctcattcctg aacctttgat accaacaaaa tgatacaatt
    66181 tattttgatt ttccatttga atcctcttct cttatctagc gtccattctt ttagctatta
    66241 cattcaacac gctcctcatt atcttataaa cgattgaaaa tttcaaccaa atttatttgg
    66301 aaaggaggat tcgcttgcta aaatggtcaa gtacgagaaa aatccgtttt tattgactct
    66361 ttaattctgg tgtaagaaga ccaaacttcc tctgatatat caatgtgagg aataaaatct
    66421 tttcctttcg gaccatagcc gttctcatcg tcatggagac gttccatttc tcctaatact
    66481 agcgcatgga aatattcctt aggccattga tgattcagtt cttttgctgt aaagatgatc
    66541 tcttcagaaa agtgaaggat ttccggcaca aatggcacag cattcgcgaa aatagtttgt
    66601 tcattttgcc atactttctc aaaagttgct cgagtcctgc gttgcagtgt cggatcattc
    66661 atcaataaga ttttttctgg tacagctcct aaggaatgaa gaatctccag tgaaaaagtg
    66721 gcgttctctc cagaatttgt agacttcgat tctatcagaa aagccttatc gggcaaatca
    66781 tagacttctt ttagatactg acgacagatt tcactttcac tcatgccatc ttcaaaatga
    66841 aatccttgct tttcaaaatt ctcataaagg attctagtcg catgccccac ccctccgacc
    66901 aaaaacaatt gatctacttg gccatttaaa tacatttgtg ctgctttatc agctaagata
    66961 ggaagacagt ttccagctaa aataagtgta ggtgccgtca gttcctcaaa atttccctct
    67021 tcaggtgcgg ctaaaaaatt taatagctga ttccagtctt ttagattcct ctgctcactt
    67081 ttttccaaag gccttctatc ctttcatctg attttttgtg cttcattaaa gtcttctctt
    67141 tttgtctcaa tccatttgat ttctccatga catcttccac aacgatattt gcgtacatcg
    67201 attcttctct tgcggcagat cgtggcagaa caatcttggc atcgataata ctccatcttt
    67261 atctgtttct tcgtcaaggc tggtgcatag cgcaaccctc ctgttttttt caaaagatac
    67321 ttgaaatcca tatctttatg ctgataccct cttccagcta gatgaagatg ataatggcaa
    67381 agttcatgtt tgatgattcc tgcaatcgtc tcttcgtctg actcttcaaa tagcttcgca
    67441 ttaaaatcta aatgatgatc gtttaaatga tagcgcccgc cagttgtacg taagcgtgga
    67501 ttgaacattg cttggtgctt gaaaggaagc tggaagcttt ttaatgatat ctcttctact
    67561 aactgctgca gttcttcttg tgtcaatttt tgttactcct cattgttact cttcataagg
    67621 ggaaagcatc gtcaaactga ttctgccttt tttcgtatcg acttgttcta tccaaactgt
    67681 tacgatatct cctactgaca cgacatctgt aggatgcttg acgaattttt tgctgagttt
    67741 cgatatatgg acaagtccgt cttgcttcac accgatatca acaaatgcgc cgaagtcaat
    67801 gacattacgg accgttccag tcaattccat ccctggtttc aagtcttcca tactcaatac
    67861 atctgtacgt aataagggcg ctggcatctc atcacgcata tctcgtccag gttgtgtcag
    67921 cccagctaaa atatcggcta acgtttcttc tccgactgat aggctttcag ccagtttctc
    67981 tacggataat cgtgtcaatt tttctactgc ttcttctgta ccaagctctt tttctgaaag
    68041 ttggactgaa gttaatattt cttttgcaat agaataactt tcgggatgga tacctgtgtt
    68101 gtccaaaatg tttttcccac cagggactcg caagaatccg attgcttgtt catatgcttt
    68161 tggtcctaag cgtggcactt ttttcaattg agttcgtgcg gtgaattctc cgttttcttc
    68221 acgataaatg acaatgtttt gggcagttgt tttattcaat cctgatatat gctgcaagag
    68281 ctgcgggctt gctgtattca catccacacc tacttggtta accgctgttt ccacaacaaa
    68341 atccaattgt tcagccaaac gtttttgaga aacgtcatgt tggtactggc ctactccgac
    68401 agctttagga tcgattttga ctaattcagc taaaggatct tgcaggcgac gggcaataga
    68461 aacagcactt ctttcttcaa cttgtagatg cggaaattct tttcgtgcaa tttcgctagc
    68521 ggagtaaaca gaagcgcctg cttcgttgac gatagcgtaa taggttttat ggtcggcgga
    68581 tttcaactgc tcagccacaa aaagttcaga ttcccgactg gctgtaccat ttccgatagc
    68641 taccatatct acttgatatt tattaattaa ttggataaaa gctggtccag cagcttctct
    68701 ttttgcttgc gctgcaggtt tatgaggata aataacttcg attgctaaaa ctttccctgt
    68761 cgcatctacg actgctagtt tacatccagt acgataagcc ggatcaaatc ccaggacaac
    68821 tttacctttt agtggcggtt gcaacaaaag attacggagg ttttcgccga aaatagcgat
    68881 tgcttgctca tctgcctttt cagtcaattc attgcgcagt tctcgctcga ttgctggctg
    68941 aataaagcgt ttataactat cctgataggc ttctctgacg aatgaagaag aaggagaggc
    69001 aggatttttg actatttggc gatccaagta agctaaaatt gctgcttcat ctacttgaaa
    69061 gaatactttc agaatatctt ctttttctcc acgattagta gctaatattc gatgagaaac
    69121 cattttatgg acgggttctg caaagtcata atacatttca tatacgcctt tttcatctgc
    69181 ttgctcatcc ttgacattgc tgacatacat acctttgtta tacgtataag accgaatcca
    69241 agtccgaaat tttgcattat cgctgacttg ttcagcaata atctcatgag caccgtgcaa
    69301 cgcttcttcg gcagaagaga cttctttttc tttgtcaata tatttttctg cttcagattg
    69361 cacctctcca tctgtaagct gcatcagcca cttcgcgagt ggttcaagtc ctttttcttt
    69421 agcaatcgtt gcttttgtcc gtcgtttttg tttgtatgga cgatacaaat cttccacttg
    69481 ttgcattttc acggcttggg tgatttctgc ttctaactcg ggagtcagtt tcccttgttc
    69541 atcgattagc cgaatcactt cagttttacg tttttctaag ttttcaagat aggcataccg
    69601 ctcttcgatt tcacgaatct ggacttcatc aagacttcca gtcatttctt ttcggtaacg
    69661 cgcgataaaa ggaacagtgt ttccttcatt taacaaatta agtacagtag tcaactgctt
    69721 aggacgatag tctgaaagtt ctttttgtac aagctgaatg atcgtctggt tcaaattttc
    69781 cgtcattaaa atgcctcttt tctgctaaaa attgcttctt tattctatca tactttttat
    69841 cctgggttaa actactgaaa gaaacaatat tctctataaa aataaaaaga gccgcaacaa
    69901 agtcacagct ccttcattct ttccattagt cagattccat gccaaggtcc ttcgttgttc
    69961 tgatattcaa tatcttgaag aataccttcc ttgtcaaaaa caaccccatg caatgaccct
    70021 ccgaatacag ccccaccgtc cattccgatt ttatgatcct gaatccagag gtctgttgtc
    70081 tgcatatctc catggagcat tggtgtaatc gtatgtccaa atacaattgt cttacctgta
    70141 ttgtttttcc cttcatgaaa tggttccctt atccaaataa agtctcttag acttgtctta
    70201 cgccagtctt tctttgtcaa atccacaccg gcatggacaa aaagataatt ttcccattca
    70261 taatacaagg ggcgctggac taaaaattta atcagttctg aatatctcga ttggatcatc
    70321 atcgagattt cagttgggga gtattcctcc gatgcccctg ggtgaatcag gctttcaaac
    70381 gtttcttttc caccatttct catataaggc gcataccagt cctccggtga ttgcagaaat
    70441 tgcaaaaaat attcttcatg gtttccccgg aggtaaatgg ctcctgtttc ttcgactaat
    70501 tgctttccta ataaaaaaca ttcttttgta cgaggacctc gatcattgag atcccctaat
    70561 aaaacaagct gatggatctt tggatcataa tagtgaataa gtttttcaaa aagctcatgt
    70621 ttgccatgga catccccaat agcataaatc aatgatttca tgtggatcac catcctcaac
    70681 gctagtatag cgcatattgg aaatggtcga caatcaaaac tattgttttc tatttaatta
    70741 aagctgtaaa ccgcagttct gcttcttctg gagagattcc atggtcttga acatagcgat
    70801 tgcgcggatg tttcgcacac tctatgctac atgctcctaa atgtttttct tcattttcaa
    70861 tggaagcaag aatctgacga ttgcactcag gattgctaca attgatatat cgttcacatg
    70921 gtgttccgtc aaaccagtcg cgaccgacga tttgtttatc tacttggttg atatcgacag
    70981 cgatccgttc atcaaacaca tacatcttgc cgtcccataa ttctccttgg acttcaggat
    71041 ccttaccata agtagcaata ccgccatgca gctgtccgac atctttgaat ccttcacgga
    71101 caagccaacc agaaaacttc tcgcaacgaa tgccaccagt acagtaggtc actacccgtt
    71161 tttccataaa ttcttctttg tgctcgcgga tccagtctgg aagctctcga aaactgcgta
    71221 tatctgggcg tacagcccct cgaaaatgtc ccaagtcata ttcataatca ttccgtgcat
    71281 caatcaccac tgtctgttca tctaaaatag cttctttaaa ttcttgcggt gaaagatagg
    71341 cacctgtcac ttggtttgga tcaatgtcct cttctagctt taaacttaca agctctggac
    71401 ggtatcttac aaacatcttc ttaaaggcat gtccttcgct tggatcgatc ttgaacatcg
    71461 tatcagcaaa tcgaggatca gctttcattg ctttcatata ggcagtcgtg ttttcaacgg
    71521 ttccagacac agtaccattt attccttctt cagctactag aatacgacct ttaagatcca
    71581 aagatttgca aaaggctaaa tgatttttgg caaattcctc tggttcttcg atttttgtat
    71641 aattgtaata aagcagtact tgataatcca tgtatttctt ccttccttct tttcgttcct
    71701 aaacagtata aagaaggcgt tcgcatttga cgatttattt gcttgtgtat aattacgcat
    71761 ggaaagtttt ttgtttacat aatattatta tttgaattaa aaagacttcg ctttcctgtt
    71821 tcgcacagaa aaacaaagtc tttatttcta ttatttacct gtaaccgcaa agtagttgcc
    71881 atcgggatca gcaaagttaa agacatattc ttctccaagc tgtaccatat cacctaatgt
    71941 gactgattgc gtctgcattt ttttatatag tccaaagata tctttactgt aaaacatcaa
    72001 agatggggca ctagtagctg tgccaggtga atgggactca acaaatgctc gatcatataa
    72061 cagaaatgag gtttgactgt cctcaactcc tacttcaatt ataagcgtcc catccatttc
    72121 ttgacgatct ttttccgcaa agccaactgc tctccaaaac gttgcatttt tttctacatc
    72181 gtccacataa agcatgattt ttatttcatt cgtaaacat
//
LOCUS       DAPBBV010000008        68199 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.008, whole genome shotgun sequence.
ACCESSION   DAPBBV010000008 DAPBBV010000000
VERSION     DAPBBV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 68199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.008"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(41..484)
                     /locus_tag="RD486_000720"
     CDS             complement(41..484)
                     /locus_tag="RD486_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662475.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(500..1660)
                     /locus_tag="RD486_000721"
     CDS             complement(500..1660)
                     /locus_tag="RD486_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7662476.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            2167..3867
                     /locus_tag="RD486_000722"
     CDS             2167..3867
                     /locus_tag="RD486_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662477.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(3969..4802)
                     /locus_tag="RD486_000723"
     CDS             complement(3969..4802)
                     /locus_tag="RD486_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDT7662478.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(5106..7271)
                     /locus_tag="RD486_000724"
     CDS             complement(5106..7271)
                     /locus_tag="RD486_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7662479.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKNPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7531..9825
                     /locus_tag="RD486_000725"
     CDS             7531..9825
                     /locus_tag="RD486_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDT7662480.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            9818..10483
                     /gene="pgmB"
                     /locus_tag="RD486_000726"
     CDS             9818..10483
                     /gene="pgmB"
                     /locus_tag="RD486_000726"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDT7662481.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            10476..11483
                     /locus_tag="RD486_000727"
     CDS             10476..11483
                     /locus_tag="RD486_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7662482.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            11505..12524
                     /locus_tag="RD486_000728"
     CDS             11505..12524
                     /locus_tag="RD486_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7662483.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(12805..14172)
                     /gene="nhaC"
                     /locus_tag="RD486_000729"
     CDS             complement(12805..14172)
                     /gene="nhaC"
                     /locus_tag="RD486_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDT7662484.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(14281..15702)
                     /locus_tag="RD486_000730"
     CDS             complement(14281..15702)
                     /locus_tag="RD486_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7662485.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(15945..17822)
                     /gene="tdc"
                     /locus_tag="RD486_000731"
     CDS             complement(15945..17822)
                     /gene="tdc"
                     /locus_tag="RD486_000731"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HDT7662486.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRNVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(18113..19369)
                     /locus_tag="RD486_000732"
     CDS             complement(18113..19369)
                     /locus_tag="RD486_000732"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDT7662487.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(19481..19686)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            19949..21250
                     /locus_tag="RD486_000733"
     CDS             19949..21250
                     /locus_tag="RD486_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDT7662488.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(21319..21918)
                     /locus_tag="RD486_000734"
     CDS             complement(21319..21918)
                     /locus_tag="RD486_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7662489.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            22172..23053
                     /locus_tag="RD486_000735"
     CDS             22172..23053
                     /locus_tag="RD486_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662490.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            23066..24676
                     /locus_tag="RD486_000736"
     CDS             23066..24676
                     /locus_tag="RD486_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HDT7662491.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(24753..25412)
                     /locus_tag="RD486_000737"
     CDS             complement(24753..25412)
                     /locus_tag="RD486_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7662492.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(25695..26360)
                     /locus_tag="RD486_000738"
     CDS             complement(25695..26360)
                     /locus_tag="RD486_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HDT7662493.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(26507..27112)
                     /gene="dhaL"
                     /locus_tag="RD486_000739"
     CDS             complement(26507..27112)
                     /gene="dhaL"
                     /locus_tag="RD486_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HDT7662494.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(27140..28150)
                     /gene="dhaK"
                     /locus_tag="RD486_000740"
     CDS             complement(27140..28150)
                     /gene="dhaK"
                     /locus_tag="RD486_000740"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDT7662495.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(28125..28571)
                     /gene="dhaM"
                     /locus_tag="RD486_000741"
     CDS             complement(28125..28571)
                     /gene="dhaM"
                     /locus_tag="RD486_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HDT7662496.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            28674..28994
                     /locus_tag="RD486_000742"
     CDS             28674..28994
                     /locus_tag="RD486_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDT7662497.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(29106..29975)
                     /locus_tag="RD486_000743"
     CDS             complement(29106..29975)
                     /locus_tag="RD486_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7662498.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(30071..31375)
                     /locus_tag="RD486_000744"
     CDS             complement(30071..31375)
                     /locus_tag="RD486_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7662499.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(31372..31881)
                     /locus_tag="RD486_000745"
     CDS             complement(31372..31881)
                     /locus_tag="RD486_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662500.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(32056..34191)
                     /locus_tag="RD486_000746"
     CDS             complement(32056..34191)
                     /locus_tag="RD486_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7662501.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(34274..35929)
                     /locus_tag="RD486_000747"
     CDS             complement(34274..35929)
                     /locus_tag="RD486_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7662502.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(35931..36245)
                     /locus_tag="RD486_000748"
     CDS             complement(35931..36245)
                     /locus_tag="RD486_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7662503.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            36415..36675
                     /locus_tag="RD486_000749"
     CDS             36415..36675
                     /locus_tag="RD486_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDT7662504.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            36689..37003
                     /locus_tag="RD486_000750"
     CDS             36689..37003
                     /locus_tag="RD486_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDT7662505.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(37733..38287)
                     /locus_tag="RD486_000751"
     CDS             complement(37733..38287)
                     /locus_tag="RD486_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDT7662506.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(38413..40342)
                     /locus_tag="RD486_000752"
                     /pseudo
     CDS             complement(38413..40342)
                     /locus_tag="RD486_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(40648..41364)
                     /locus_tag="RD486_000753"
     CDS             complement(40648..41364)
                     /locus_tag="RD486_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDT7662507.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(41365..43188)
                     /gene="glpO"
                     /locus_tag="RD486_000754"
     CDS             complement(41365..43188)
                     /gene="glpO"
                     /locus_tag="RD486_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HDT7662508.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(43202..44698)
                     /gene="glpK"
                     /locus_tag="RD486_000755"
     CDS             complement(43202..44698)
                     /gene="glpK"
                     /locus_tag="RD486_000755"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDT7662509.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(44834..46294)
                     /locus_tag="RD486_000756"
     CDS             complement(44834..46294)
                     /locus_tag="RD486_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7662510.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(46284..47579)
                     /locus_tag="RD486_000757"
     CDS             complement(46284..47579)
                     /locus_tag="RD486_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7662511.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(47911..48588)
                     /locus_tag="RD486_000758"
     CDS             complement(47911..48588)
                     /locus_tag="RD486_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HDT7662512.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(48618..49709)
                     /locus_tag="RD486_000759"
     CDS             complement(48618..49709)
                     /locus_tag="RD486_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDT7662513.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(49810..50244)
                     /locus_tag="RD486_000760"
     CDS             complement(49810..50244)
                     /locus_tag="RD486_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7662514.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(50828..52285)
                     /gene="ascB"
                     /locus_tag="RD486_000761"
     CDS             complement(50828..52285)
                     /gene="ascB"
                     /locus_tag="RD486_000761"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7662515.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(52282..54177)
                     /locus_tag="RD486_000762"
     CDS             complement(52282..54177)
                     /locus_tag="RD486_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7662516.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(54235..56010)
                     /locus_tag="RD486_000763"
     CDS             complement(54235..56010)
                     /locus_tag="RD486_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDT7662517.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(56060..57556)
                     /locus_tag="RD486_000764"
     CDS             complement(56060..57556)
                     /locus_tag="RD486_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7662518.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(57750..59372)
                     /locus_tag="RD486_000765"
     CDS             complement(57750..59372)
                     /locus_tag="RD486_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDT7662519.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(59700..61013)
                     /locus_tag="RD486_000766"
     CDS             complement(59700..61013)
                     /locus_tag="RD486_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDT7662520.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(61258..61482)
                     /locus_tag="RD486_000767"
     CDS             complement(61258..61482)
                     /locus_tag="RD486_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662521.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(61502..61924)
                     /locus_tag="RD486_000768"
     CDS             complement(61502..61924)
                     /locus_tag="RD486_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HDT7662522.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(62066..62776)
                     /locus_tag="RD486_000769"
     CDS             complement(62066..62776)
                     /locus_tag="RD486_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662523.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(62794..63291)
                     /locus_tag="RD486_000770"
     CDS             complement(62794..63291)
                     /locus_tag="RD486_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662524.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(63328..63780)
                     /locus_tag="RD486_000771"
     CDS             complement(63328..63780)
                     /locus_tag="RD486_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7662525.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(63915..64520)
                     /locus_tag="RD486_000772"
     CDS             complement(63915..64520)
                     /locus_tag="RD486_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7662526.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(64970..65590)
                     /locus_tag="RD486_000773"
     CDS             complement(64970..65590)
                     /locus_tag="RD486_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7662527.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(65592..66461)
                     /locus_tag="RD486_000774"
     CDS             complement(65592..66461)
                     /locus_tag="RD486_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HDT7662528.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(66484..66891)
                     /locus_tag="RD486_000775"
     CDS             complement(66484..66891)
                     /locus_tag="RD486_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDT7662529.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(66910..68199)
                     /locus_tag="RD486_000776"
     CDS             complement(66910..68199)
                     /locus_tag="RD486_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7662530.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        19619 a        14441 c        11829 g        22310 t
ORIGIN      
        1 aaaaaattag gctgggagca ttatttcgtt attctgttca tcaaaaatca gcgttttgat
       61 tccatttcat cacaagttcc tcctcattta ctgcttcatc tttttgctgt gtttgaattg
      121 taaaaccttg tgaaagatag aaatgaatag ctgattgatt tttttgatag actgtcaaag
      181 tcagtgtttt attggtttct tttatttttt tcattagttg cgtaccgatt ctttgttgcc
      241 ggtattccct tttcacaaag attcctgcga taaactgatc aatcacccca gcaaaaccaa
      301 taatttcttg atctatttct gctaagtaaa tcactgcatc tggtaaagct ttcctaacag
      361 attctacttg attctcccaa taagttgatg gaatgaattc atgagaatcc aagttagcat
      421 gcagccaaat cgatagaaca gattccagtt ctttggcaga caattttgtt gttgtgcgga
      481 tcattttttc tctccttact tattcattga ttttaaaata aaaaccattt ttttgaagct
      541 cttttacaag ttttcgcccc tcaaaaaagt atatcttctc ttgttttact tttctaatac
      601 caaaagaaac agcaacttta ggatcatcag ctgaaacgat tcgataagtt ccaccaggca
      661 attgatccag cttgactttc ccatgatggt cgctttgtac tgaaaacggc acaccatttc
      721 tagtaagtgt ttttttctta tgtttcaaaa tgaatgaact accatttacc ggtttccctg
      781 acgaatcact aataataaat gaaaaatcaa gcactttttt acttaatcta tactgataga
      841 ttagtcgtcc gataaacact aacagtatga ctacagctat tatcgttcct gcaagaataa
      901 accattgccg catggttctt tcctgatttc cttttccttc ttcttttttt accgattcgt
      961 tataaggaat ccgatgtcct gtcactagca aacgatgcgt gttgatcata tacggcgtac
     1021 atgtaagcaa ggtaactaag tcttctcctt ctgaaatcgt tagaacagac gtgtcatctg
     1081 gcagtaccac ttgtatattt ttaacttgat aagccaattt ctcccccaaa acagtcaaaa
     1141 taaacgtgtc tccgttttct aaacgatcta attcggtaaa taaccgtcga ttaggtaaac
     1201 cgctgtgagc agagatcact gaatgcgtcg aatttccacc aagcgggaaa gaggttcctt
     1261 gcaagacgcc tgctccattt tcaaggatcc taccattgag ccgatcataa agtgaaatat
     1321 ttaattggat cttaggtata ttgatacttc cgatcagcca ttcctctaat tggctggatg
     1381 ttgtactttc atttctgttc ttttcattga aaggatcagt accaggattg aatccttggt
     1441 cagttaatcg ttggtttttc tcctccattt tctttcgctg cacttcaatt tcagctgcgg
     1501 tccgtttttg tacttgttcg atacgttttt gatcaataaa actatttaaa gaatccacat
     1561 aaaatggata taaagcgatc agtaacccta cgacgataca tattaataaa aacaaacgaa
     1621 acaaaagtcg acgagactgt ttttgcttac tctgcttcac atgtgtcctc ccttgcaagt
     1681 ttttttgttc tttcttttat tatatgggtt caggaaaaaa atagaaaatg aaagccgatg
     1741 aggttgtgaa aaagctgtcc tgcatcaagt aataagtaca gcccaaaaaa atagctactc
     1801 atattttttg ttgggttggg cttattaccg cagatgcaag cttttgaaca ccgtttaagg
     1861 aagaggttgt gaaaactgcg ttatgctttg agtaataaga gcgctagtca gaaaatagct
     1921 tctcatattt tctaggctag tgagcttatt accgagaagc agctgattga acaccgttta
     1981 ccgagaggtc atgaaaaagc tactttgttt cgagtattaa gaaaaattct gtttcaaaac
     2041 aaggagatgc aacaaaactt atgtcgcatc ctctctcctt agaactttca cttatgtttt
     2101 tcttgtaaaa ttcataaata ttttcatgaa ttttctaatt tcttgcctac ctctcgcata
     2161 ggatatatga tgaatttatc taaagtttgc aaaggagttc gacaattgaa aaaatatggc
     2221 ccatttttag caattttttt cattgctttg gcatttctca tgcctcattt attcacacat
     2281 aaactaattt tgggtgctga tgccccattc cattacaatc ggttctatga tgccgcgcaa
     2341 caaattaaat atggggattt ccattatttt ccttcccttt atggattcca gcaaagtggc
     2401 aggatcgtga atgccgttta cggcccattt ttcgcttatt tacaaggatt gatcgtgttg
     2461 cttgcaggta gctggtttca ttatcagatt ctttcaaatt tcattcttta tcttatttca
     2521 ggattttcta tgctgatttt actgagatat gtcaatgttc gaaattgggt aagtgtacca
     2581 gtagccgttt tattcatgag tacgtattct attcaatact ggtctatcaa ccaaggattc
     2641 actagctggg ggacttgttt ttatccttta tgtatgatcc ctattgctga tttcgtcctt
     2701 cataaaaagt tccctgttat caaagtcgct gtctcagtgg gacttatgac acagatccat
     2761 ttactgtctt cgatcatgtt agctttgatg tatatccctt tttatcttta ttactttttt
     2821 aaccagactg aaaaaggaaa agcactgctt caactgatta agtcggtctt gctttatttt
     2881 gttctgacag caaatatttg ggcaggatta gctattgttt acagtgggaa taagattctt
     2941 cctccttttg ttaacagaga aatgagtcaa aaggcgatag atctggatgg cagttattgg
     3001 ctccattacc ctaaggcctt tcctatattg atattatcag gttttttgct ttttattttc
     3061 tttcaacaaa agaacacctt attccaaaaa atcgtgttgt acacaagtct tgttttcttt
     3121 tttctttcta ctagcttgat tccatggacg acattgatcg aaaaaaatgt gccttttatt
     3181 agtttgatcc agtttccatt tcgatttttc gtgccattta cgctattgct tctactttac
     3241 cttgcccttt cactgaacca gtggtctgaa caaaagtggt tccgtctttt aagtatattt
     3301 ggcattctta ttttttcagc acagacgatc cagaacttat accagcatct ggaaaagtgg
     3361 gaaaatgaaa catttgtcag tcgacatact tatctattcg atacgccgga agaagcaagg
     3421 aaaacattct tcagcaaaga tatgtctacc agcttgttcg ttttccaaaa aaccacacct
     3481 gactatctgc caatctataa ggagacaaaa gacaataaat acgaccggta taacgaagaa
     3541 atactagaaa acgaaacaac ttttataaaa acacatccag gcggtctttt gacaatcaag
     3601 tggaaaaaca ctggggacaa aactgttcat atccctgtta tcgtctacga tcggactgtg
     3661 ctacagcaaa atggaaaaac attgactgat tatgaagtaa cagatatcgg gaccccaatc
     3721 gtgaagcagc aaaaaggaat caacgagctc acgcttcatt atcaaacgcc aatctatttc
     3781 tatttcattc tttctcttac tttgattggc tggtttacct tgctatgttt atttatttat
     3841 catagataca agcttttacg tgcttaggca aaagggataa atacatccga tcaaaaaact
     3901 ctccaaacgg tataatcgtt tggagagttt tattttaatc agttttttta tgttatatgt
     3961 tatatttttt attcgttcac atctaattcg atttccaccc cgtagtgatc actgatgatt
     4021 ggactatcga tcccatcaaa aatccgttga tattttttaa cctgcattcc ttcagggacg
     4081 aaaataaaat ctatacgcaa tttttctgta ttttgttccc aaccatctat tttcttttcc
     4141 acagtagctg cttttccttt ttcattcgcg acaacatacg aatcttgaag aagaaggcaa
     4201 ctttctctta cagtataata accttgagag tctactggat tattgaaatc acctaggaaa
     4261 aaaagtggta cgcgagtttc caaaaagtag ttttccaagt ttttccactc aaaataaaag
     4321 ccactttttt tatctgtcca ccaagaaaag tggcagctcg agacaaaaat gtcctgatca
     4381 tctatctttg ttttcccaat caagatcttg cgtgtctgat aatcttcttt cttttgaaat
     4441 tgggagacgg taaggacctg actttccaat gtttttttcg taagcagtgc atttccttct
     4501 tcatatttat cataaccgat gtggctcatt tcccaactcc aaaaatactc ttttccgtgt
     4561 tcctttaaaa gctgaactaa acggtaggca aaattatctt tacggatagg tacttgattc
     4621 tttaccggac agaacttcat tagcttcgca ggttctactt cttcagattc cagtaattgg
     4681 ttgatttctt gtaaagcaat cacttcataa tcttctaaca ggatcttatc tgctaattct
     4741 tgcaattttt tctctggttc tggctcaagc cagctatgcg tgttgagtgt catgaatttc
     4801 attggttttc tccttgtctt catttcgaaa caaaagggtt gtgacaaaat ttttgtcaca
     4861 acctctccag caaatagtgt tctcctgcta actcctcagt aataagctca atggaccagg
     4921 agctattttt tgtttggctg tttttatcac ttggtgcagg gcagcttttt cacgacctct
     4981 ccactaaaca gtattcaaac tgctgcttct cggtaataag cccaaccaaa cgaaaaatag
     5041 gaggagctat ttttgtttgg ctgttcttat gacttgatgc aggacagctt tttcacaacc
     5101 tctccttaca ttttaatgga gccgatcact ttaccagctg tcactgtacc taattgcttg
     5161 atcactactt cttctacttt atcgtttgta aatacgatca tgatcgttgg atctttttct
     5221 tcgttttgga tcacatcaag atccatctca gctaatttcg ttcctgttcc tacttcttgg
     5281 ccttctttga cagcaatctc aaaagctggc tgattcattt ggactgtatc gattcccata
     5341 tggatcaaaa cttcgatacc atctttcgtt tccagcccaa ttgcatgttt gctagggaaa
     5401 atacttgtca cttttccagc gatcggcgca acaacttctc ttgatgttgg aataacagca
     5461 aagccgtcac ccatcatttt ttgtgagaat accggatttt ttacttcaga taaaggaatc
     5521 acttctccag aagctgcgga aactagttct tgttctatac ctaagtattg cttactacct
     5581 gcttgtccat ttcctgtaga aaccatttct ggctctggaa tctctgctcc tgattgcagc
     5641 agatcttcga tatctgattt caagacatct gcttttggtc cataaactgc ttggactcca
     5701 ttgtctttga cgatcaatcc catcgcccct gctcgtttcc aggcttcttc agtccctact
     5761 ttttctcgat catttacact tacgcgtaac cgagtcatac aagcatcgac atctttgata
     5821 ttttcttttc ctcccagcaa atgaatgatc tggaccactt gctgatctgc tgttcctgtt
     5881 ccgctgttag atacaacggt ttcttcactg tcattgtcgt aatttccgtt acgtcccggt
     5941 gtagcaaagt tgaatttttt gatcaagaaa tttgctaaga aatacgtaac aacaccaaaa
     6001 gcgatcacac acaacacgaa gttgataaga tctccaccta gacccgcttt gatagctaac
     6061 ggtgtccgag tcagcaattc gatattccca aatgaatgga cccgcaatgg caagatatct
     6121 gccatcgcaa atgcagcccc ttggatcact gaataaatga catataatgg cacagcagca
     6181 aacataaaca tgaactccaa tggttctgtt acacctgtta gaaagacagc caacgctgct
     6241 gaaaaataca ttgatttata tcttgctttc ttatcaggat cgacattacg atacatcgca
     6301 aaagccattc ccatcaagat acctgaagaa ccaatcattt gtcctacttt gaaacgagcc
     6361 ggcgtccagt tatgcaacac aaactcatat tgcgacatat cccctgcacc tttaagattc
     6421 actaaatcag tggcccaagc caaccataac ggatcttgcc caaatacttg tgtccccgcc
     6481 tgtgcgcctg ataaaatctc atacgatccg ccaagctgtg tatagttgat aggaatcgtc
     6541 agcatatgat gcaatccaaa tggcaatagt aaacgttcta atgttccaaa taaaaacggt
     6601 gctagaatcg gtgcgctttc ttgtgattct gcaatccata aaccaaaatt attgattcca
     6661 gcctgtacgt ttggccacac cacagcaaga atcaatgcca cgattgttga ccataagata
     6721 acaacaaacg gaacaaagcg ctttccattg aaaaatgaca aagcatccgg caattttcta
     6781 taattatagt acttattata agccattgcc ccgacaaatc cagcgatgat ccctacgaat
     6841 actcccatat tcaaagctgg tgcttccaat acacttgtaa aaaatccttt aaccatgatc
     6901 ttcgtaccga acagagtgtg ggtaaatgca tcttcattcg caagcatgtc acttgtgaca
     6961 ccaaagatag ccccagtgat ccgattgatt aaaataaatg agatcccagc tgcaaatgct
     7021 ccgcctgctc tttcttttgc ccaacttcct cctattgcta aagcaaataa aatatgaaga
     7081 ttaccaataa ttgcccaacc aatattttca attactccgc ccgttgtgac aagcggcgtc
     7141 caatcaggat tgatcaaggg aattgatttc cctatactga tcatcaaccc agctgccggc
     7201 ataactgcta ccacaaccat taaagccttt ccaaattttt gccaaaactc aaaactaaat
     7261 atctttttca ttccgtttag ctcctttacg caatcggttt cgttaaacgt attatagcgt
     7321 gcgttttctt ttttgtaaat gctttatttt ttatttttct gtctatacca ttctataaaa
     7381 cctataatac gtgtgttccc ttctataatt ttctcctaaa aatttatttt tttaagcttt
     7441 tttctatgaa atattttctt ttgtctattg acttgtgcaa tcggttgcgt ttattatgaa
     7501 cgtataaaac agctcattag gaggagaaaa atgaaacaga tcaaacgact atttgctatt
     7561 gatccatgga aaatcagcac gacacaatta gataaaaaaa atcttcgact gcaagaatct
     7621 ttaacaagta ttggaaacgg ttatatgggg atgcgcggga actttgaaga aacttactca
     7681 ggggaccacc atcaaggtac ttatttggcg ggtgtctggt atcccgataa gacacgtgtc
     7741 ggctggtgga aaaatggtta tccagaatac tttggaaaag tgatcaacgc cttgaacttt
     7801 atcgcgatag atatttcgat caacgatcag ctgatcgact tggcttcttt ggaaccagaa
     7861 gacttttact gggaattaga tatgaaaaat ggtgtattat ctcgtacatt cacaatcact
     7921 acttctacta ataaagtacg catttccttc gaacgttttc tgagcattgt caaaaaagaa
     7981 tcagcttata tctatttaac tatagaaatg cttgaaggta gcggaacagt caaactcgta
     8041 tcaaaattgg atggaaatgt tcaaaacgaa gacagcaact atgatgaaca tttttggaat
     8101 gagattgatc gtggaactat agaagaaatc ggctatttga cgactaaaac tattccaaac
     8161 aactttggga ttgaacaatt tactgttact gcagcaatgc gccatttcgt taatggaaaa
     8221 tcagtcatcc ctgactatca cgaagatact ttagcattac atggttgctt gtctgcagaa
     8281 ttatctcaag gtgagacatg gtcagtggaa aaagaaatta tcgttcttac tagtagagat
     8341 attccagaag cgcagcaagc agaaaaagct gtctcagaat taacgaacca gacaaacaat
     8401 tatatccaag caaaagaaga gcaaacagcg gcttgggcag aacgatggaa gcttgccgat
     8461 gtggtcatcg aaggagacga agaagcacaa caaggtattc gattcaattt gttccaacta
     8521 ttctctactt actacggcga agatgaacga ttgaatatcg gccccaaagg attcacagga
     8581 gaaaaatacg gcggagccac ttactgggat acagaagcgt atgctgtccc tctttatctt
     8641 gctttagcca aacctgaagt aactaagaat ctgctgaaat atcggcataa tcaactgccg
     8701 caagcaatcc acaacgctca gcaacaagga ttaaaaggcg cgctttatcc tatggtcacc
     8761 ttcactggtg tcgaatgcca taacgagtgg gaaatcacat tcgaggagat tcaccgaaat
     8821 ggcgcgattg cctatgcaat ctacaattat acgaattaca ccggcgatac ggaatatttg
     8881 aaaaatgaag gactggaagt tttagcagaa atcgcacgct tctgggcaga ccgtgtccat
     8941 ttttcaaaac gagcaaataa atacatgatc cacggtgtga ccggcccaaa cgaatatgag
     9001 aacaatatca ataacaattg gtatacaaat acgatcgcag cttgggtctt gcgttacacg
     9061 cgagaaaatt atttaactta tcaaaaagaa gctgctatca ctatcagcga agaagaacta
     9121 gccaaatgga aagatatcgc agagaacatg tacttcccag ttgacgaaga attaggaatc
     9181 tttgtccagc atgacacatt cttagataaa gatctcatgc ctgtatccga tattcccaca
     9241 agcgatcttc ctctgaatca gcattggtct tgggacaaaa tccttagatc ttgcttcatc
     9301 aagcaggcag atgtactaca ggggatttat ttcttcaatg atacttttac aaaagaagaa
     9361 aagcaaaaaa actttgattt ctatgaacca atgactgtcc atgagtcttc cctttcgcca
     9421 agtatccatt cgattttagc agcagaatta ggaatggaaa gcaaagctgt agaaatgtac
     9481 cagcgaacag ctcgcttgga tttggataat tacaataacg acacagaaga cggcttgcac
     9541 atcacttcca tgactggtag ctggttgtcg attgtccaag gatttgctca aatgaaaact
     9601 gcccatgatc agttgagatt cgcaccattt ctgccaaaaa cttggaaagc ttattctttc
     9661 catatcaatt atcgcggacg tttattgttc atctcagtca cagatgaaca agttactttc
     9721 gagttattag aaggttctcc tctagaaatt tacgtctatg aacagtctta ttctttagcg
     9781 gatcgtctag aaataacgct aagaaaggag gaagcaaatg tttaaagggg tattgtttga
     9841 tttagacggt gtcattaccg atactgctga attccattat cgtgcttggc gaaagcttgg
     9901 tcaggaaatc ggcattacga tcgaccacac attcaacgaa cagctaaaag gcgtcagccg
     9961 agaagactca ctctctttgc ttttagctta tggcggaaaa gaacactctt tttcaaagga
    10021 agaatttgca gaattagcga aaagaaaaaa cgattattat ttagagatga tccagacgat
    10081 cgaaccaaaa gatgtcttcc ccggggtcgt gcctttactg gattctttaa aagaagaaaa
    10141 aatcaagatt gctcttgctt ctgcaagtaa aaacgggcca ttcctacttg aaaaaatggg
    10201 tcttacacct tactttgatg ctattgccga cccggcagaa gcaacaaacg gaaaacctgc
    10261 gccagatatc ttcctccttg cagcaaaagc tgtcggacta aaagcagaag aatgtatcgg
    10321 gatcgaagac gcgcaagccg gtatccaagc catcctctca agtggcgctc aaccaattgg
    10381 cgtgggacgt gctgaagacc ttggagagga gatcccgctt gtccctgata cgacttttct
    10441 tacgatcgat tacttgaaag aaaagtggca tgaccatgga taatccagag atctccgtcg
    10501 taccagttcc agagactgaa ataaagaaaa tcacattgaa gaacgactac ttagaagtcg
    10561 ttcttctcaa ttacggtgcc cgcctgcacc aaatcttcgc accagacaaa gaaggaaaat
    10621 cagaaaatgt tttattgtct tacgatcgtt tcgaagatgt tctaacagac aaaagctttt
    10681 ttggagcaac tgtcggacct gtagccggaa ggatccggga tgcttcttgg ggtgagcata
    10741 gattggagaa aaactgcgga tcacaccata tccacggtgg cacgaaaggc tggtctttcc
    10801 aattttggga agtagaagtt ttcaaaactc catcatcaat aggtgtggtc ttttacttaa
    10861 aagatgaatt ttctacctat ccaggaccaa tcactgctac gatcacttac cgtttaacaa
    10921 aaaacgaatt agagatgaca acctctgcta gtagccttgt tgaaaccatc tgcaatccga
    10981 ccaaccatgc ctacttcaac ctttcaggaa atggaacaag agacatctat gaacatcagt
    11041 taacggtctt tttagatggt gtgcttgaat tagatcaaga aaaactgcct actggaaatt
    11101 ggacaaaaaa agaaaaactg ccaatcgact ttagaaaatc cccaacactg caagagatcc
    11161 ttgcatgtta tccagatgga ctagatgatg tatttctttt gcatcatcct aggctttcca
    11221 aaacttcctt acaattattc gagaagcatt ctggtcgcca aatgactata gcaacttcta
    11281 ataaaagtat ggtattattt tctacgactg gattcgaagc tgatttctct gtcaatggaa
    11341 aacagatgca ttcaaactac ggattagcaa tcgaaccgca agaaatccct gatatcgttc
    11401 atttccccaa atttggatcg atcaacctcc atcctggtca agaacggatc agtcagacga
    11461 tttatcggtt ctctgcacaa taacaagaga aaggtgtttt tatcatggct attaccgtaa
    11521 aagatgtggc gaaaaaagcc ggtgttgcca cctcgaccgt ctctcgtgtc atcaacgatc
    11581 atcctagtat ttccgagaca acaaagaaga aagtccgaaa aattatggat gaactaggtt
    11641 atgttcctaa catgactgcc cgcaatctag gaaaacgcat ttccagtgcc atcggcgtaa
    11701 tcttaccccc tcttgattca aaagagcgga tcggtaaccc attttatctt gagatcatgg
    11761 aagcaatcaa cgaagaagcg cggaattatg atatgactac agcaatcgct actgctaaaa
    11821 attttgaatt gctgttagag aacgtccagc gtatgcattt acaaaaacaa gtagatggtt
    11881 ttattctagt gtattcagat agtcaagata ctgtcattga ttatttatac caaaaccaca
    11941 tccctttcac tttgatcgga cagccttatc atcatgagaa cgaaatcgtt tatgtagata
    12001 atgataacca gcttctaggt aaacaagcaa cagaattttt gatccagaat ggacataaga
    12061 atatcctgtt tgtgacaaac acgactcatg aaagtttgta tttcgaacga tatttcggtt
    12121 atcaaaaagc aatgatgatg gctggtcttc ctgcgttatc cagtgtagta ctagagcatc
    12181 cggaggatta tctgtccttt gagaaaacgt tgaaagaaaa cgaagccaca gcattggtgg
    12241 tcattgacga tatcttcgcc cttcgcacga tgcagttggc gcaaatgtat ggctatgtca
    12301 ttccagagac actctccgtc attagcttca acaactcgat cttctcaaca ttaacacacc
    12361 cttaccttac aagtatcgat atcgatatct ccgaattagg acgtgtcgct atgcaaaagc
    12421 tgcgcgaatt gatccatgaa gaattgagca gtggcgtacg tttggtcatc cctcatcgct
    12481 tgatcaaaag agagacagtc gttcctttag aaaacccata ctaaatagct gactcactaa
    12541 atacgctgac catttatcct atggtcagct ttttatgtaa aagaagatac tacttctaac
    12601 acattgttta tctgtaaaaa agagcgtggg acaaaagtaa agaacacttt tgtctcacgc
    12661 tctaaacacg tataaacggc ggaagcagaa gcaactcctt cggaaataag ctgaaattca
    12721 caaaaattta aaaagcaatt ttcttgagtt tcttcttatt tcttggagtt aaacgcttct
    12781 gtcccagcct cttttttcct tccttcaatt ttttacacgt cgacgattca ataaaaaacc
    12841 gcctaatatt gtaaagacag gtgcaagaat cgagaaaaag gcgaatggca agtaatgcaa
    12901 cgcgctaact ttcatcgttc ccataatgaa tgtgccgctg actccccacg gtacgagaga
    12961 attgacggtc gcacctgaat ccgctagtgt tcgtgtcaaa taggtttttg ataagccaac
    13021 gtcatcaaaa gaacgcttga atgtttctcc tggaagaatg atggacagat actgttctcc
    13081 aacgatcaga ttgattccga tacagctcaa ggcagtaaac ccgactaaac gagaaggtcg
    13141 gtccatcttt tcttttaatt cttgaacgat ggtatcaacg atcagatatt tgatcagtaa
    13201 cccacctaat gccaatgcaa gtaaaatcaa actagcagaa cctaacatac tcatgatccc
    13261 gcctcgagaa agcagttcat ctagctttgg atcaggtgta tttgcgacat aaccattcat
    13321 caagatgtct gctgcttttc cgaccgtcaa acttttctca tggataaaag aaagaacgag
    13381 agcagctgtc gatcccgcta gtaatgtagg gatagccgga atttttttga ttgccccccc
    13441 aaataaaata actagtggaa tcaatgtcca aggagagatc caaaagctcg ctttcatgtt
    13501 ttggatcatt tcattgatac tagctagatc ggctgaatga ctgttatgtc ctaatatcgt
    13561 ataaaaaatc aacgaaagga cgaatgctgg gaaatccgta taacgcatac cagcgatatg
    13621 ttcgaataga ttaactcctc caatacccgc tgccaagttg gtcgtatctg ataaaggcga
    13681 gcagttattc cctaaaaagg caccggaaac gactgcgcct gtagtcattg catcattgaa
    13741 tccaagtaaa tgaccgatcc ccaaaaaagc aattccaatc gtcgaaatcg ttgtaaatga
    13801 actgccgaca gtcactccga caattgcaca aacaagaaat gctgtcggta aaaagaaacg
    13861 cacagaaaca agtttaaatc cataaaccat aatcgtaggg atggttccag ataaaatcca
    13921 tgaagcaact aagacaccaa tcaaaagaaa aatcaggatt ggaatgatcc ctggagtgat
    13981 tcctttgatg atcccgtcat ggatctcatc ccatgtgaac tttttaaatc tgccataaaa
    14041 caacaaacac atgaaagctg caaggatcgg gatatgtggc gagagctgga atccgatgat
    14101 cagtactcct aggagtgcca acaacacgat caatacagcg atactttctt ttaaagaaat
    14161 atttttattc atcgtcgatc tcctatttca aatgaaaagg ccctgccatg aaaaaactat
    14221 tcacttggca ggacctccta ctaaatcagc gacaaaacgt cggctgaaag acttattttt
    14281 ttatttttct tctaaacttt tttctacctc aatcccccaa gaatctttct tgaagtgatt
    14341 gatgatcaat ggaataacga acatgaccac tgtgatagct gctactaata atgcatcact
    14401 caatgtcgct gtacctaatg tagcaaatac gacaacgatg atagagaaga tcagcatgca
    14461 gctgactacc caagctaatc cgtttccgtt tttaccaatt cggtaaggac gttcgaattc
    14521 tggatgtttc ttacgcattt taagcaatga aacagcaatc aaaatgtaca cgatacaata
    14581 aataacagtt gtagcatttg taagtgtcaa gaatacagca cttacgtcat ccattacacc
    14641 ataaagcaaa gcaaataatg aaataacgat tgattgtgtt agaacgacat ttctagatac
    14701 gccgtatttg ttttctttat ggaatccgaa ttttggtgga aggaatcctt cacgagctac
    14761 ttggatgatt gtttttgatg gtccagtaac ccaagctgat aattgtaaaa gcacaccaat
    14821 aaataccatg aagctgaaga tatttccgat cacttctggt aagcctagga tttgacagtc
    14881 aatcaagata ggctgcgtga tatttgctaa ttccattttt ccatctggta cgacatttgc
    14941 tacaagcatc gcattgatga cattcaataa aactaatccg atcaaagcga taaatacgcc
    15001 ttttgtataa ttttttgttg cgtctttcaa acgaggcatg taaacagaac tcatttcgat
    15061 cccaacaaaa ataaatgtga taccagctaa gtatttcaat gaatcaatat gttccaagtc
    15121 agggaaagct tttgaccatg aaaagtcacc tagatagccg tttgagacta gtccgacttt
    15181 gaaggctgcc aaaacaccta aaacgaacat gatgactact gggatatata cccctagcca
    15241 tacaccgatg ttcccgccga cttttgccat atcgaatttc aagttcaaga tcgtgatgat
    15301 ccagtagata actaaaatac aacctaaaac gaaccagtga ttattgccaa gttctacatt
    15361 accaaatgtg tttcctaaca atggtcctaa agtagaagcg accattacca tacctgggaa
    15421 catttgcacc cataatagcc atgcaacgac aaatccccat ttgctgccca gtgctgtttt
    15481 tacccataac tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac cggaaaccat
    15541 tgatatcgga ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca atgtccaacc
    15601 gactgcggct aacgtaggaa tactccgaac cgttgcacac agtgccattg tcagaccgat
    15661 aaaggtccca agacccattt tacttacttc agatttactc accgttgaca ctctccttga
    15721 ttttttggat aaaataacgg tgtctttgaa gtagtttcag caataaacga aacaattcag
    15781 cgaatatttg aggggattct ttgagtttat tgcttgaagg gtttcttcaa agacaacctc
    15841 aaaacaaagg gatcgaagag cttaggtctc cccttgctct tcagatccaa acatgcgtca
    15901 gaaacagtta gtattcaagc tgttttctaa catgattacc ttgcttattt tgcttcgctt
    15961 gccaataatt ggtctgcgta gattttttcc aatttttctt gaagagctgc tttgattttt
    16021 tcagcatatt cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac gctggcacgc
    16081 aatacagtta cttttccggc acggttccat tcttcatctg agaatcctag ttggttcaca
    16141 aattgtaatg ggctgttgcc atagtctggg atagcaaagt cagtatgtga agttaagaac
    16201 tcattaccgt aaatgcttcc tttcacgtat gaagaataat catatacgtc atggttcaat
    16261 ttattcattg caactaagtc atcgttgcct ttttctttga atacatagtc taccatattg
    16321 aaatctggat aagttaatgg atgaacttcg atttctttgt ctcctacttt aaatgacaag
    16381 tcattcaaga agttgtagaa acgatgtgca ccttcgattg atgcacccat taatttacca
    16441 tatcctgtga cattcaaagg taagacatgg tgtgctgccc aaacgctggc tgctgttgcc
    16501 cctgcttttg aaccttccaa gatataagcc ccaagtaatg ctgggatatc tgcgcctttt
    16561 tcaaatacat atgtcgcaaa gtaagagata acgtttctca tgcggatatc tttgatgacg
    16621 ataccaccgg cagaatatgg aacatagccc attttatgtg ggtcaatcgt tacagattct
    16681 gcttcttcga ttgctttata tgcactgtgt acttcttcta agatataatc tttgttttct
    16741 gtaaagacat tgtatttgta atgaacatct tttaaatctt caaatggaat gaagttgttg
    16801 tcttcgtcta agaaaatcgc acggccgtat ccgccataag cagcatctac gtgtaagtag
    16861 aagtaaatac cgtctttttc taatacgcga cgcaatgcaa cgattttatc gataccgtcg
    16921 attgctcctt cttctgttga tcctacaaca ccgactacac ctaggattgg tgttttttca
    16981 gctgctagac cacgaacgat tttttcaagt tcgttgatgt ccatgcgata gttgtggtca
    17041 actggcactg gaatcacttg gtctaaaccg ataccgatga tgtcggcagc ttttagccat
    17101 gaatagtgtt tagtttgtgg aaccaaccat tttcctaatt tttctaaatg ttttccgcta
    17161 cgtgctgagt gagctttgat ttcgtcgatt ttttctggga cgctgtctaa cagattcatg
    17221 atttcttctg ttgacaagtt cattaattcc caatcgcttt ttccagcaac tagttcaggt
    17281 gtcacttctt tcattgcaag cggcaatgat ttgatgttgc gggcatacca aagtccttct
    17341 aagtttgcta aagaaccatc agcaacgatg tggccccagc catctttata gctcattaat
    17401 tttgcaaatt ccattcctac ttcttcttcc atttggcttg ttgcaggaga agattcatag
    17461 gcaacgttat taccattcca tagcatagca aaattgtacg ctagtaaaga tggcatcaat
    17521 gtttcagagt tcatatgacc ccagtaacgt ccggcattat gccaaggaac ggaatgggta
    17581 cgcatccgcg ctgaaatttc tgatagaaca tcctttgttt tattcacagt gtgttcaaaa
    17641 ctagcactgc ttttttcttc tggcgtaata ataggcatgt cttgaggcat gtagttttga
    17701 cgccagccta aatgttcatc caccaattca ttcaacaaag ctttatagat ttggccgttc
    17761 tcagctttgt ccccaatgaa tagggcattt aggtttagat ctttcgacaa tgattcactc
    17821 atagtgaaac cctcctaaaa aaatatttaa attttgtcga gccctacatt acacctgttc
    17881 ttctattctg taaactaagt tttggcctga tttttaatca tattttaata tgtatcaatt
    17941 atccgaattg ttcacacttt tgaaataatt aaaaaaaacg agggaattta caaatgtaaa
    18001 ctccctcgca aagattgtat taacgacaac cagcgttcta ttttaggatg ggtttcaaaa
    18061 ttggaatgtt gtaatagtat ttcccttttt caaggtaaaa acttactaaa ttctaatcaa
    18121 ttactttggc caaaaagtaa tttttcttac cttttcgaat aaccacaaac ttaccatcga
    18181 attcatcgga tggatttatg acaaaattta aatcggtaac gcggtcaccg ttaatactta
    18241 tagctccgtt tgaaacatct tcacgtgctt gacgtttaga tggttcaatt tttgtggaaa
    18301 caagcagttc cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc attttaccga
    18361 atccttgcgc gatttcttcc gcatttagtt ctttaatatt tccagagaac aatgcttgcg
    18421 ttattttttg cgcttctttc aagtcttctt cactatgcac aaatcttgta acttcttctg
    18481 ccaaacggcg ttgtgcttca cgtttctcag gttctgtctc tacttttttc gctaagtctt
    18541 cgatttcttc ttgagacaag aaagtaaaga atttcaagta tttcactaca tcgcgatcat
    18601 cttgattcaa ccagaattgg tagaactcaa atggtgaagt tttcttcgga tcaagccaaa
    18661 cggcaccgcc tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc aatgggatcg
    18721 ttaaaccgaa cgcttctgct tctggtcctt ctaattttcg gattaggtct aatccagctg
    18781 tgatatttcc ccattggtct gctccaccga tttgcaattg cacatcgtat gttttatgca
    18841 gatgcaaaaa gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat gagattccta
    18901 cttccaaacg gctggcaacg atatcttttg ctaacatcgt gttgatgttg aagtttttac
    18961 cgtagtctct caaaaattca agtaaagaga tttttgacaa ccagtcgtag ttgttcacaa
    19021 atgtgatatt tgcatcttta ccaaacaatt ttctcatttg attggaaagt gcgtccacgt
    19081 tatgttgcac ttgttccatc gtttgcaaca cacgttctgt tttgcggccg cttgggtcgc
    19141 cgatcgttcc tgttccgccg ccaatcagaa tatatggatg atggcctgcc aattggaatc
    19201 ttttcatcat cataaatgga atcaaatgtc cgatatgcat cgaatcacca gttggatcaa
    19261 cgccgcaata aagtgaaatg ctcttttctt caacgagctc gcgaagtctt tcttcgtttg
    19321 tttgctgatt aatggcgtcg cgccaagtta attcatcaat aatattcatt ttactgacct
    19381 ccgtgtagtt tttttatgaa agcaggaacc tgctagcata tgtaattaat tatttcttca
    19441 ggataggata ggaaataaaa aaagtccctt ggcatataag ccaagggacg aaatctcgcg
    19501 gtaccaccca atttgtatgt ctagatatcc aacatacctc tcgaacattt aacgctgtcg
    19561 cgtggcaatc actgccaaag actcctgaaa tgtaattcgc tttaaagcat gtactggttt
    19621 gcagcgacca ccagctttct gaaacattgg ctttaacaac tacttcgttt cgatcttcgt
    19681 cttgttatta ttaatatgtg tctatcatag agcgcaactt tttctttgtc aacagaaaaa
    19741 ggatattttt tttaaattcc tcattttttc ttttttgaat ccgctctaat tccgaacatt
    19801 ttattttcaa ttattgttaa aagaaataac tttttctgta ttttttctgc aatttatcga
    19861 gaagtcactt tactttgcct cttattcttt cttcgttaca ataaggaatg ggacaagtaa
    19921 aaaaatgaaa aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta ttttaggagc
    19981 cacttctgct ttaactatcg ttattttaat tctaagtttg ttttttgtca tccgatcatc
    20041 tacaaaaaaa gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa aagaaccgac
    20101 agatgataag caacaactag ttactcaagc aaaaaatctg gctcaaagct acgattatga
    20161 ccaagcgatt gcgttattgg aaaaagatag taagaacgga tctactgaaa cacaacagct
    20221 tcttcaaaca ctaaaaaagg agaaagaaca actgatcgac tggtctgatc ctactcagat
    20281 ctctcatgtc tttttccaca gcttgatcgt ggacccgcaa aaagccttcc actctcaaca
    20341 ggcacaagga tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt cgatcgaaca
    20401 actttatcaa aatgattttg ttttagttaa tttgaatgat ttgatccaaa aagacgaaca
    20461 aggaaatctt tcctttaacg ggcttgcgct acctgaagga aaaaaaccat tggttctttc
    20521 acaagatgat gtcagctatt atgaatatat ggataattcc ggttttccta gccgattggt
    20581 cgtatcaaat aacaatgaaa tcaaaaatgt ctataaagag aaagataaag aagaaatcgg
    20641 tgactttgac atggttcctc tgatcgatgc ctttgtcaag aaacatcctg atttttctta
    20701 tcgaggcgca aaaggtacct tggccctgac aggttacaac ggagttttag gttatcgaac
    20761 atcaaaatct caatatggag acaatgaaaa aacaaaaaaa gagattaaag aagctaaaaa
    20821 agtggcggaa cagttgaaga aagacggctg gagctttgct tcccatacat ggggtcactt
    20881 gaatatgact caagcttcac tagaagatgt aaaaaaagac aatgaattgt ggcagcaaga
    20941 agttgcacct atcctaggaa aaacaaatat tctgatttat ccatttggtg cagacatcag
    21001 cgactggcag ccttattcag cagaaaatca aaaatttgct tacttgaaga gtcaaggttt
    21061 cgatattttc tgtaatgtcg atgcttctac accagcttgg ggacaattag gtacggattt
    21121 ctatcgaaat gctcggatca atatcgatgg cattcgtttt caatctgatt tagacggaaa
    21181 aaatcctatt cttgatccat tcatcaatgt ccatgatgtc tatgacaaag aagcacgcga
    21241 atctgcttga ttttacgtca tttatgaacc aaaaaagccg aactgacatt ttatcgtcag
    21301 tttcggcttt tttatgcttt atttcttctt cggtgcgatt cccttgatca ggacttctgt
    21361 ccattctgct gtatatggaa gcagttttgc gtatatctcc ggcttagaaa ttccttctac
    21421 cattgcttga aaatagagga tcaagaactc atccgaatat ttcaaatcca cttttccttc
    21481 tttccgccct cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg tatacgcatc
    21541 catcgcgtca gaaaattctt ttttttcttt ttttgtatag tatgtcatca aatcgatata
    21601 aaattgtttg ttcactcgat tgagataacg gattttgttt tcactcatgg caatcagtgt
    21661 ttcttcaaat ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta aatcattcat
    21721 aaatgcaaaa aatacttcat aaatcagccc ttccttgctg ccaaaatatt taaaaatcgt
    21781 cgctttactt acctgagcgt tctcagctac cttatccatt gtcactccag cggttcctat
    21841 gtctgtgttc atcaagtcaa aagctgcttg taaaatctct ttctttttct cttgtgctct
    21901 cttttcaaaa ccgttcattt gtagagcctc ccgtaatttt aaacttttat aatatatata
    21961 gttcaaattt attctgaggt ttattataac tatctattga gaaagtatca agctagcaat
    22021 tccttgttta tgaattcatt gacagaaatt tataaaaaga atattatgta ctaaaataat
    22081 aaaaaaagtt ttataaaaag gtataaaacc tttttattaa actatttaat cttgtttagt
    22141 atatattttt agaaaaagga gtggggtttt tatggcagaa atcgtcaaag tcacacattt
    22201 gaaaaagagc tttggtcgtt tcgaagcttt aaaagatgtc tctttcaccg tacattcagg
    22261 tgaagtcgtt ggatttatcg gaccaaatgg ttctggaaaa tccacgacga ttcggacact
    22321 tttagggatt ataaaaaaag acggcggaac ggcaacgatt tttgggcaag atgtatggga
    22381 agatagttta tctatccatg aacgtctttc ttatgttcca ggcgatatct ctttgtgggg
    22441 aaatttgact ggaggagcga tcatcgatct cttcatgaag cttcatggaa aagggagtgc
    22501 tcaaaaaaaa gatgaactga ttcaacgttt ctctcttgat cctaagaaaa aagcaaaaaa
    22561 ctattcaaaa ggaaatcgcc aaaaagtggg cttgattgct gctttggctg ttgattcgga
    22621 tctctattta tttgatgagc ctacttctgg tttagatcct ttgatggaaa cgattttcca
    22681 agaagaagtt gaaaaattga aagaacaggg caaatccatc ctactttctt ctcatattct
    22741 cagtgaagtc gagcgactag cggataaagt cgtgatcata cgcgaaggaa cactcgatga
    22801 agaaggaaca ctcgatgaat tgcgtcattt gactcgttcg accatcacta tagaaacaga
    22861 agcagagaat agtcacttag cacaattgaa cggtgtccat gactttgtgc aaaaaggtca
    22921 cctcgctcaa tttgctgctg ataacgaagc tttcgatgtg attttagctg aagcgtccaa
    22981 attaggtgtg aaaaaatttg aatctattcc accgactctt gaggatttat tcatgagaca
    23041 ttatgaagga tgaggaggaa gcgaaatgac tgataaattt tcacgctggt ccaccctttt
    23101 ttctcaaaac cttagccgtg actggaaaaa gatcctgata tggctagtcg gtgtcactgc
    23161 tttttctggt ggttttgtcc ctgcgtttga agaattgact tccggacaag gattagctgg
    23221 attatacgaa accttgcaaa acccggcaat gattgcaatg gtcggaccaa ctccagcttc
    23281 gaatgctgct gagtatactt taggagcgat gtatgcaaat gaaatgttgc ttttttgcag
    23341 tttgtttgct gctgtgatct ctgttttaca cgtggtgagc caaacgagaa aaaaagaaga
    23401 acttggtctg attgaactta ttcgttcctt tcgagtcgga cgtcaagcaa actctttagc
    23461 tgtcatcgct gaaagtattc tgatcaattt gcttttagca atatcgatca gctgtacgat
    23521 gatttttttc caagcggatt cgatcactgc agaaggtgct tggctttttg ggctatctgt
    23581 aggtagtatg gggattttgg ggagtgccgt tgcactgttt gctgcacaac tgatgccaag
    23641 ttcagccagt tcgaatggtc tgtctttagc gtttttaggt ggactttacc ttctacgagc
    23701 aataacagat gtagctgatt cctccctttc gatgtggaat cctttaggct ggtcttattt
    23761 gacctatcca tttacaacta acaactggat tcctttgctt tatttgtttt tgttcagtct
    23821 aatcttgata atcagttcat ttgttttaga ggaacatcga gatttgaaca ccggctatat
    23881 ccccgaacgt gaaggaaaac cgtatgctaa acgttctctt ttatccttgc gtggtttatt
    23941 attctatcta aataaaggga tgacaatcag ttggcttatc acttttggtt tgatgggggc
    24001 ggcatacggc tctatctacg ggaatatgca acagttttta gaaagtaacg acttaatgaa
    24061 acagatgttt atccaatctg gcgtctcaat tgaaaaaaac tttacaagca cgatcatggt
    24121 agtcttgatt tgtctagctg ctattttacc aattgctagc atcaatcgtt tatttacaga
    24181 agaaacccac ggacgtatga atcagctgtt cgcaacaaaa atttctagga accaacttta
    24241 ttggaccaat atgttactag ctattctatt tgctatattg gcaatcctga ttagttctgg
    24301 tgcactaggg ctttctgctt tggcttcgat gaaggatgcg aaagacatgg atctattgat
    24361 gtttcttaaa gccgggttca atttcctgcc tgccgtttta gtgtttatcg gaattagtgg
    24421 ctttctattc ggatggcttc ctcgaatcgg taaacttgct tatatctact tagcttactc
    24481 ctttgcactc aattactttg gcggaatttt ggatttacca gaatggtttt ccaaaacagc
    24541 tgtccctagc tgggttccac ggatgccaaa cgattctttt gatctttccg tgttccttac
    24601 gttatcatgt atcagccttg cactgttcgt ccttggttct attggttata ggcgaagaga
    24661 cttactagaa ggataataaa aaagcatgta caatttcatg ctagcctcca aatctgggtc
    24721 aaaaatccaa catttggagg tcattttttt atttacaagt cttctaactg ctctttatca
    24781 atgatccaga cttctcgatt ctttcttttt acataaccat tctcctctaa taatttaaat
    24841 tttctagata aagtttcggg ggtcgtaccg ataaatgcag caagttcttt cattttcatt
    24901 ggcaggaaaa agtgatcctt ccctgtcgct ttagctaagt caagcagata gacagcgact
    24961 cgttcttcta ctttttccat catcaaaaaa gttgtctgct gctgtacttt tgttaatttc
    25021 tcaacgttga ttgctaaaag tttcagacta agggcgggat aatgcagtaa gagttccgag
    25081 aaatcttttt gtctcaatat gcaaatttcc gttttttcta gtgcttcgcc aaataaagac
    25141 tcatttggaa cgcctagcaa ctggctctct ccctcatatc cgcccggctc tattactcgt
    25201 aaaagctgtt cctttccgct agcagataat tgatacactt tcatactgcc ggaggccacg
    25261 atcactaatt gaggttctcc attcggcgca agaatctgtt ctcctttttc cacatagtga
    25321 tgtttgacaa gtgcgtgtac tttttcttga tcttgctgta ctaagtgatt gaacaaagga
    25381 acaaatgaaa cacataaatg atcatgactc ataatctctc ctccttctaa acagctattt
    25441 ctaataaaga aacataactt cccttattcc aactgataat tttcttttat catagcataa
    25501 acgtcaagcg aaccagatac cagcaaatag agtggatttc tttttgtccc ttgctttatt
    25561 ttccttcttt tgagacctta agtaattgat tcctatcaat tttttaaata tttacttttt
    25621 gaataatcaa aaacaaacct tcactcgcaa gccgagagta aggtttgttt ttcgcattgc
    25681 ttatttcgtg ttgtctattg aaatttttcc gcacctagct tttgatatag tggtgctagt
    25741 tcttgtaagg tttcagcggt tatttgctca acgtgttcga tttcttgcgg atagaagaat
    25801 agtttaccca tttgaaaggt tcggtctctc atcgcttttt tcaactcttc ttgtttcttt
    25861 gtatcggaca aatagtcaga caaagctaag tggtcgtcaa gttcatgttc tggttgcggc
    25921 catatgtaat aatccttgat atcgactgtt ttgctccact ctttcagtat cgcaagcaac
    25981 tggttatacg ctgcaatgct accatatcgt tcttcgcttt tataatgttg gtacatcaaa
    26041 tagatttggt attgtttttg attcaacaaa actgctagac aggcattctc gtcttgacga
    26101 gattcgcttc ggtacgcgct ccaaaaatga ctgcgtaaat tccagccatt cgtccagctt
    26161 tcgattttag gtttgctcat gccgtacata tcaggcaaaa gtgcagctgt ctggagctga
    26221 atctctttcc atttttgcca gtgttcttta tattctttct tgatttgttc aatcttatct
    26281 gttggatggc tctctttgag ctgtttgaat gcgtagattg gtcgatcaaa caactgataa
    26341 tctgattttc caagttccat tgtttcgcct ctttccgtta tcttttgtat tctacctgaa
    26401 ttttgcgata tggacaaata gaggttgtga aaaagctgtt ctgcatcaag tcataagaac
    26461 agccaaacaa aaaactgcga tgagcatcac cgcagtttta ttgaacttaa ggttgattga
    26521 tcacatctaa aagcgttgaa aataaaatgg cactagaagc agctcctggg tcgatatgtc
    26581 cgattgcacg ctctcctaga taggaagctc gtcctttttt agctaccaag actttggtgt
    26641 gttcttttgc ctggtcaatg atttcttttg ttaaattccc tgccttcaat gcctctgtga
    26701 ctggcagcca aacatctaac atcgttttat cgtcagcttc tgcctttcct cggctttgaa
    26761 tacccgctgt tccctgctcg atcacttcgc ctaatttttc ttgagaatca atagaatcga
    26821 cctcttttgt cgctttcatc atgttcatga atgcagatcc gtataacgga ccagaagccc
    26881 caccgacttt cgatatcatc gccatagaga atactttgaa tgtatcgctg attgtttcag
    26941 gatgatcggc ttgaaaagct tcttcataag ctgaaacccc tcttcccatg ttatttccat
    27001 ggtctccatc gccaatcggg gtatctagat cactgagata ttgtttgttc tgattgattg
    27061 cctctgcaaa ttgcgtgagc cattcttgga tttcttgaac ggttagtttc atattatcac
    27121 ccttttatct tgagattttt taccatgaaa tcgtctgtac attgctttct aaagaatctt
    27181 tccattgtgt ctccgtcaag tcgatcagtg ttagagaaag accttgcata tctagtgagg
    27241 tcataaaatt accgactttt cggaaaacta cattgacgcc tctttcttcc aacagagcta
    27301 aaacatcatt catgaacacg aactgttcca tcaaaggcgt cccgcccatt ccgttgacta
    27361 gtacacctgc ttcttttggt aaattcgagt aatcatctaa aatcttagta acaagttcct
    27421 ttgccagtac tttagaaggc tgcatctttt ctcgacgata gcctggctca ccgtggatac
    27481 caacaccata ctcgatctca tcttctccta gttcgaatcc tggtttccct acttctggta
    27541 cagttgctgc tcgaagcgct agaccgatcg tcttagttgc ctgtacgacc ttttctccca
    27601 gttctttcaa ctcagctagg gaagcaccgt ttcttgctgc atcgcccacg attttgtgta
    27661 caaggacagt acctgcaact ccgcgttttc cagcagtata cgtactattt tcaacggcga
    27721 tatcatcatc tacgatcaca ctttctactt caatatcgtc catagcagct aattcctttg
    27781 ccatatcgaa gttcaatgca tcccctgtat aattcttaac gatcagcaaa actccttttc
    27841 cactatcggc ttccttaata gccgtctgaa tctgatctgg agttggagaa gtaaacacat
    27901 caccaagcac cgctgcactt aacatccctt cccctacaaa cccggcatgg gatggttcat
    27961 gtccgcttcc tccaccagaa accaaaccaa cttgttccgc tttctgattc ttggctacaa
    28021 cacgggaaga ttctacacga tgaacaagtt ctggatagct ttttactaat ccttccagca
    28081 tttcttcgac aatattgctt ggatcattca tgattttttt caatttattc ccatcctttc
    28141 tttccggcat tttgtgcttc tgttaagatt tgctgagtat catctgttat accggcagtg
    28201 atggctgctg caaaagctcc ttccactaaa ggcgcatcca ccagatgata acgttgctgc
    28261 tgctcttctt ccaacatgtc ttttgccagt tccgagttca ataccgcgct accgatatcc
    28321 gcaaaaacaa aataactagc tgcatcgctt gattcattga ctgcttctac gattttcatc
    28381 gggtctgatc cgatctcgcc atttattccg ccgagagaaa aaatttgcac ctcttcggat
    28441 ttttgcatct gctcaatcat ttctttaata ccatctgtta ctttttgact atgagaaata
    28501 agcaaaatac tttttttcac aagaatcttc ctttctttta catagttgct aacgattggt
    28561 ttcgctttca ttaatgaaca attcaagtat ataataaatt tctaattttg ggaaaatatg
    28621 tgtagtgctt cttgaagttt gttatacttt aattaaaaga gaggagtgat cgaatgatta
    28681 caacaacaac gaacagtgta gagggaaaag ccgtagtagc ttataaaggg atcgtttttg
    28741 gtgaggtcat tactgggatc catgcattta aagacttgga ggcggggttg cgaaatatct
    28801 ttggcggccg ctcaaaaagc tatgaaaacg aactaatggg tgcaagagaa gaagcacttg
    28861 ccgaaatggc cgaacgtgca aaagcattag gagctgatgc gatcattggc gtaaaaatgg
    28921 actatgaagt attaggcagc gacaatggca tgctgatggt cacatgtagt ggaacagctg
    28981 tctccacgag ataagtaggg gacatctgtt ttaataacta aagagagatg ggacatgtag
    29041 tggcactcaa gaattagatt tttcagtcta acttcgaggt actctacctt cccatcctct
    29101 cttttttatt tctttttgcg gatgattccg taagctgctg cgactaacac acccgcccct
    29161 gctaaggaat aactgacaga agctgttttt tcatttgttt ttggcaaagt ctgacttgtt
    29221 gatttggatg gctctgtcgt ttgctgaact gtttctgtcg tgcttccaga ggtcactgat
    29281 ttttctcctg ccgaatgcaa aatatctttt attcgttgga aactagctgc taagtcagct
    29341 ttttttgctt caaaatcatt agcaactgtt tgtgcttcgc tgatctttcc gtggattgct
    29401 tgactggccg ctgtgatatc cgcttgagtt tgacttagct ttccagaagc tgtttgagca
    29461 acctgattta attgctgatt gaattctttt gcttgttgga tcttcccgtc aagatctgtt
    29521 tggacagctt ccgcttttgc tttcgcttcg gcaagctttt tctcaagttg tgcacggtca
    29581 tttcccactt tatttttaag atcagctaaa tcttgatcga ttgctgcttg gtcttctttc
    29641 aatttgtttt ttgcagcttc taatgcttct tcgagttctt ttcttttatt ttccaagtct
    29701 tgcaaatgat cgatttggtc agaagaggta gaactattta ttgatgtatc ttctgaagat
    29761 gaaatcgttt ctcctgaatt atctgtcggt acattggaag tcatttctgt ttccgaggca
    29821 ccgttttcag caccagaaga gcttatggtt gttgaaggtt ctgtttgagc aggttcagaa
    29881 gtttccgcaa aagctgtctg tcccaataag aaaatactgg aaacagcaat tggccagatt
    29941 aacggcttca ttcttttttt catcactttt cccatcctta ctacttttta actaatttct
    30001 tattataagc aaaaatgttt ggaagaacca taaacacaac aggctgtttg tctaaaaaac
    30061 ggtgcatctt ttattttttt gtacgttccg ggcttttcca tgtcccgctt ccataaccta
    30121 aaatcgtttt gactgctgga atgaaagtcg tcacgatcgt tatcgcgttc actatccaga
    30181 acaaaagcat atatagtggt gcgaaaagaa ggtatttcaa ttttcttcgt cgatcatcta
    30241 caatcagcga agctagcaac tggaaaaatc ctgcgaccat ttcaaagcag atgaacacaa
    30301 aactgaatgt aaaagtaata taaatctgtt cgtagtttcc ttgatataca taatgcccga
    30361 ttaatccagc aaaaagaact acggaaatac aaaagaatat tgaccagaca atactcaatg
    30421 tttgatcaat gaagatgatc gttcttccaa tatgtttaaa aggatggagc atcacttttt
    30481 tgaaattcgt cagccagact tctgttccac cttttgccca acgttttctg tgtcgatata
    30541 gcatcttcaa cgtcacaggt acttccatga aaaagataat ctcaggagca aaaacagata
    30601 accagtcatt taactgatga tcccaagcaa tactgatgtc ttctgtcgct cgatcttgtc
    30661 tgaatccgcc cacatcgatc aaggcttctt ttcgatacat cgtatttgct ccactgtacg
    30721 cataaagacc accgaaaaca gctgactgtg ttcgtttaat gatgcccacg atacttgaga
    30781 attcaaccgt ttgagatttt gcaatcaatt tggtacgatt ttggacatcc atatttgcag
    30841 tgaccgcagc aatatgtctt gcaccagggc gaatgaaata attcacatac ctaatcagtg
    30901 catctggctc cggtaccgtg tctgcatcat tgcttaaaat caatttccct tttgcaaagg
    30961 caagtccgat attaaacgcg tgggcttttc ctttattttt ttcgatccga accacacgaa
    31021 gattagcgta ttttttcatc agtctagcta atatttctgg tgtttggtcc gttgaaccat
    31081 cgtctgtcac taatacctca tagttgtgat aattcaattt cgtcatcaaa tactcgattg
    31141 tatattcgat cacaatttct tcattatggg ctggcaccat gatcgtgatg aacggttcga
    31201 cactcaaggg aacatctacc cattcttttt gcttatgttt gtataaaaac acataacacc
    31261 agacaccaat aaaccataca aatccgccta aaatcggata agaaacgaga aaaaaataca
    31321 taatagacaa acaagtatct aagaataaat tacctgtatg ggtgattgag atcatttcag
    31381 ttccacccca ttttctttat acaaatctgc aatgaatgtc gtatctagat ttttctcttc
    31441 ggagacagaa taaaaacgga ccgtttctct ctcttctttt gttccaaaac gttccgtata
    31501 cacttcttca agtaattctt gtcttttttt caatttttca tcttcatatt caaaagattt
    31561 atttactttt ttgtatagat ttcgattgtt ccacctagtc aatacaaatg aggtaatcag
    31621 gaaactgaaa aaaatcaata caaaaaagcc gattaagaaa tacagcattt tcttttctga
    31681 taaaaaagcg tacaaggaaa aatccttggc tctttctggt ctcgttaatg ggaaaaagac
    31741 ccatataaaa ggaagaacaa cgatcatcca tcctaaaaga gccactaacg tttgccaaat
    31801 ctttaaccag taattacctt ttgaaaaata cttatctttc accaaaattg atgcaacttc
    31861 ttctcttgtt acttttttca tatcctcacc tcacgttttt ttgttacgac gtaggagttt
    31921 accatacatt tcatttcttt tcacataaag tgttcctaaa tttttcctaa gaaaaagaac
    31981 aaaacatttc tcatcagcaa atgaaaaata ttttgttctt tttatcagtt gttcttttta
    32041 ttttttatct cttaattatg ttgctctttc caatacgaca atgcttttca ttcctctaga
    32101 tatcgccgtg tacatttgtc tgcgtcttct ttgctcatct ccatcgtttt caaatggata
    32161 taagattaca tgatcaaatt ccagtccttt tgctagactc aaaggaatga tttggcagtt
    32221 ttctaatcca tatgaatttt ttttaatcga ttcttgtagc gtttgggttt cctcttctgt
    32281 ttgggtgata actgccgctt tttctccttt tagagaaacc aaaatctcag ctagtatttt
    32341 caacaattct tcagaggatc gaaaagagcg gtattcgggt tcttttcctt gcggtcggat
    32401 cgatacgatg tcgatcttct cttgatccac agcataggtt ttgaaaagct ctgtgattgc
    32461 tccgctagaa cggtaactat ttctaagatc ataccgatgg atcggcagat ggtagtcgtc
    32521 gaaacaacgc ataatatcag caaaagtagt ggaagaatta aagattgcct gattctcgtc
    32581 acctactaaa gtaaagtgag tttttggaaa taattcgatc aatagaccta attgtgccag
    32641 ggtataatct tgtacttcat caatcaatag atagcgaaat gctggtacat ttaccttttc
    32701 aacaagtaaa tgacgaatag ctaatataat gactgcttca tcaacagtac gtgtgggttg
    32761 ccaagcataa gctgagccat atcgtttttc ataaattctt tcaaacaact gatgctcatc
    32821 cacccatgcc atttcttcga tttgtctggt tatttttcga tatttttttt gtaaaagttt
    32881 ccttgcataa gctacaatac tttgttccga atcatcagaa atcaatttac cgaataattc
    32941 caactgccta tcttctgtca acgagagtac ctgattctgc acagcaggac tttttgcttg
    33001 tttcaaaaga tgattcttcc attcgctcat cagtgccttt ttcgttgctt gaagcctatc
    33061 gatcaattta ggatgagcag gaactttctc atatattttt tcgatcgttt ttttagaaag
    33121 gactgttttt ccatttttag taagtccacg gataaaattc ggatgatcta aaaacaaagg
    33181 atctgattgt tttagattat cgataaactt tttgctacgc aaacgttctg tctgctccga
    33241 tacattttct cccgtgatac gtttgaaata agcctcttca ccttctattt cctctgctga
    33301 aagctgtgaa accagctgta tgatggttag attcagtgga tttctttcac ctaatgatgg
    33361 taggacattc gaaatatagt cgataaaccg atgattaggt gatagaatca gcaagtcatc
    33421 ggatgtcatc gtatctcgat ataaatagag cagatacgca atacgctgca tgatagcaga
    33481 ggttttacca cttcctgcta cgccatttac caagatattt tgacttttca catcccgaat
    33541 gattgtgttt tgttccgatt ggatcgtagc agtgatagcc ttcatttcat tggtctcatc
    33601 ttggcctaag acttctaata atacgtcatc ttgaatagct acagacgtat caaaaaactt
    33661 gaccaaacga tctctttcca aaagaaattg tcgtctttct ttaataaccg tatcgatttt
    33721 attttgacga accgtataag aagatggacc aatcatgtta ttgtaaaaaa gttcggcaat
    33781 tggtgaacgc caatcataaa caagattttc atctgcatca tctgtgaaat ttgctgtacc
    33841 gatataaaag gattcttttg gctcattatc cagaaagtct acaacgactt ttccaaagta
    33901 gggacttttc aataaacgtt cgatctttgc tagctgattt tctgcgtttt tctgtttgat
    33961 attcatctga tcgatttctc tatttttcat ttcaatcatc gaaaaagtat ccaggttatc
    34021 taagtaactg tcaaaattca atcgaagctc gccagccatt tctttcaacg actggtttcc
    34081 ttctattttt gccgtatcca tcgattcccg cagttcgttt tttttatcaa ttagcttttg
    34141 atacacgttc ttcagatatg cttcttctaa ctgtttttgt gtgttgacca tacacattct
    34201 cctctttttt taaagtggtg gaaccgatta gtttacctct tttaagagtc gaatgcaagc
    34261 tttttaacga gtatcatttg ttaggatata tcagttcttc aggtcggaca gtttgatata
    34321 aagaaaatgc accatcaagg ttttttacgt ggtagccaga ctgcttcaag attctttccg
    34381 ctagatagct acgtaatccg ctatgacagc tgacgatata ttcttgttgg ctgtctaatt
    34441 catttaatcg gtcccgaagt tcattcaaag ggatatgttt ggcttccttg aatttgccct
    34501 tttccaattc ttctgctgtt cgcacatcta ataaaatttt tccttttgct agttctgtcg
    34561 gcaattcatg ccattgtacg gtttcactaa gcccttctgc aatgttcatt gctgcatatc
    34621 ctagcatgtt tactggatct ttggctgagc caaatggcgg tgcatacgtc aattctaatt
    34681 ccggtaaatc gaagatcgtc aaatgccctt tgattgctgt tgctaaaata tcgatccgtt
    34741 tatccacacc ttttgcccca acaccttgtg caccataaat ctcgccagtc tctggatgga
    34801 agatcaactt cagtaaaata tctgttgctt ctggataata gcttgcatga tcttttcctg
    34861 atacatgaat gacttcaaaa gacagttcgt tttctttggc tgttctttca cttaaaccgg
    34921 tggatgcggc agtcattcca aacgttcgta taattgctgt tccaataccg ccttgatttc
    34981 ttcgagaaat tccggaaatc gtgtccgcaa cttgtctacc ttgacgattg gctggtgaag
    35041 caagagaaat aagtgcatct tttccagtga tttgctgttt tacaacgata gcatccccca
    35101 ccgcataaat atcaggaata ttcgtttgat aacgttcgtc tactaggata cccccgcgta
    35161 tgcctaattc gattccagcg gtcactgcta gctggttatc aggacgaaca ccaatggata
    35221 aaataactaa atcagcaggg atggtacgcc catcatccag tcgcaatcgt ttcccgtggt
    35281 cttcaaatcc agcgacagca tgagaagtaa tcacttctac tccttgatga gacaattctt
    35341 tttctataaa agctgccatt tcttcatcca gtgttggaag aatatgtggt gcttgttcga
    35401 tcaccatgac ttctaaacct cttcttttta ggttttctgc catttccaat ccgatgaatc
    35461 ctgcaccaac gatcacggca cgctttggct gtttttctaa tgcatgcatc actttatcga
    35521 tatctggtac atttctaata gaaaaaacat tgtcggcttc tgttatccct ggaatcgatg
    35581 gaacaactgg ttttgcacca ggagataaaa ccaatgcatc gtactgttca atgtgttttt
    35641 gaccctcatg tacgacttct accgttttgt tttcgggaaa gatggctgtc acttcatgat
    35701 ttggacgcac atctaaacaa aaacgagcgg ataatgattc tggcgtttgg acaagaagat
    35761 tttcccgttc actgatttct cccgaaagat aataaggcaa gccgcaattt gcaaaagaaa
    35821 catacggtcc tttttcaaaa acaacgattt ctgcatcttc cattaatcgg cgaagccgtg
    35881 tagcagcaga cattccacct gctacacctc cgacaataac gattttcatc ttatttccct
    35941 cctactgttc gatcaaacca ttgattcatg ccaccacgta cattcactac atcataacca
    36001 gatttcttta attctttagc tgcttgttta ctcctcatcc ctgattgaca aatcacatag
    36061 acggtctttt ctttgtctcc atcatatctg tttatacttt gtaatggaac atttttagct
    36121 ccttttatat gcccgccccg gtattctgca ggtgttctaa catcaagtaa cgctggattt
    36181 tccaaaagct tttcctttaa ttctgggact gttatcgatt ttattgattg aaatagcaaa
    36241 ttcattttct gcacctcatt tacattttta taaatacctc atggggtata ttaaacagga
    36301 gctttattaa tatgtcaacc agaatgactc ttcatttttt tcactacttt ttatatttgc
    36361 ataaaatacc gataaggggt attatctaat tataaaaata gaggagaatg tgttatggag
    36421 attgataata aaaatatcct gaaccgtttg aaacgtacag agggacaaat tcgtggtatc
    36481 caaaaaatga tcgaagacga aaaagaatgt atggatgtca tcactcaatt aagcgctgtt
    36541 cgttctagta ttgatcgcgt aatgggcatg atcgttgcag ataatctgaa aaattgcttt
    36601 gagaaacctg atagtaatcc agaagaacaa gcggctaaac tagaacaagc gatcaagatg
    36661 attattaaaa agtaaaggaa tgatttcaat gaaagtcgtt ttccatattg atgaattaga
    36721 aaaatggtca gaaacaggga aaaacgtaaa aaacctgata aaagcttctc cagaaacgac
    36781 gattgtcgta tctgtaaatg gcatcgcgat taccggttat ctagactctg ccaatgcaga
    36841 attcttagat ttgcaaggag tcgtttttca cgcttgcgcc aatgctatgc gtgctaatca
    36901 tatttcagaa agttctttac ctgaacaagt aatcgttgta ccagcaggtg tccttgattt
    36961 agttgaactg caatcccaag gttatgctta tatcaagcct tagtcagtag aggttgcgac
    37021 agaagtgatc agcttcaaga aatttcggct tatttttcga agaagctact tctggaaaac
    37081 cgtgaatcaa aggttgtgaa aacgctgtcc tgcatcaagt aataagaaca gccaaacaaa
    37141 aatagcttct catatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac
    37201 accgtttaag gaagaggttg tgaaatcagc ggtttgacct aagtattaga gaaaaaaacg
    37261 ggaaaatagc tcctcatatt ttgccgtttt ttgagctaat accgaaggtc agctgattga
    37321 acaccgttta aggaagagat tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt
    37381 tgtgaaaatg gatttctaca tttttgcata aatttggctt aataccgaga aactggcttt
    37441 tgaataccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagaaac
    37501 aaacggaaaa atagctgctc atattttgcc gttttttgag ctaataccga aggtcagctg
    37561 attgaacacc gtttaccaag aggttgtgag cctaccattt aactccgaat cacaagaaat
    37621 aatttcaaaa acaacttctc ctgtttttgg ttcggttggc ttattatcga gaagtagcta
    37681 ctgggagtct atttatcaaa aaaaggaatg cgacataggt cacacccctt ttttattttc
    37741 tttgaaacat ctttcggtac tcgacagcat acaagacaaa agattgtaaa agaccgtaag
    37801 tgatgacggc aaaaatgact ctcacccaca gcgttggtaa ttctgggaaa agcagcaaaa
    37861 ggatcatgcc aacatagatg acagcagtcg ctactttgcc ataccacttc gctccactta
    37921 atttgatatt tttagatagc ccgattaatc cagctacaaa cataaagcct tcttttatca
    37981 agaatagacc aaacaacagc caaagccacg gtcgatacca tgccatagac aaaatcagaa
    38041 aaagttgtgt caatttatct gcaaacggat caagcacctt ccctaagtct gttacctgat
    38101 tatatctccg agcaatgacc ccgtctagat aatcagacaa acctgagaca acaatgaccg
    38161 ctcctgctat ataaaatgac tgtctcagca caaaataaag ataaatcggc agcaaaaaaa
    38221 tacggaatat cgataaaaga ttcggaatcg tttgtatttc tttacgccag tctgtgctta
    38281 atttcatttt atcgccctac ctcctcagca ctcttttctt tttattttag cttacacggg
    38341 gaataaaacc aatgatttca ctgtttttat ttttctttac agacactgat attatgagct
    38401 aatttgagat aatcacttgc tgttttcatc gtttactctt ctttcttcct gtcgtttgcg
    38461 catttctttt actagtactt tatgagcttt ttttgatcct cgctctaggt cacgctgccg
    38521 tttacgtgtt ttataatcga taaacagact gtctaaatcg taacctgtcg ggtacagatc
    38581 ttctgctgaa cgcaccagac gaacacgctg acgaggcacg tggattattt ttttgtctaa
    38641 atatacatca atcgtatctt cacctatatc ttcataaact aacgcttctt tttggtattc
    38701 attgacaaat atccgatcac cttttgcaaa gagctgacgt tcttttttat tctccttcct
    38761 atttgtaact gctgtcttag gaagaaattc ttttttctgt gtccgatagg ctttttccgc
    38821 caagtaacgc tctgcttgat ggatcaattt catcgacata tccattttat gagcaatcca
    38881 caaagcttgg ctttctcctg tttcttccaa cccgcaactg atatttagga cgaagtgctt
    38941 cccgatcgaa agccatagca gccggcacaa aatcttcatg atctccggcg aatttcttga
    39001 tttctccata atgggtcgtg gcaatgatca atgccccttg ctcatacata gattccatga
    39061 ttgcgatcgc tagtgcagcc ccttcatttg gctctgttcc actgccaatc tcatctaaaa
    39121 gtaccaacgt attccttttt atctttttca aaatagcagc gatgttttgc atatgaccag
    39181 aaaatgtact caacgcattt tctaaatttt ggtggtcacc gacatcgacg aaaatctcat
    39241 caaagacagc aagctctgtc ccttcttttg ccggaacttg cataccgaac atcgccatca
    39301 aagtcaataa accgactgtc ttcaacacga ctgttttgcc tccggcattt gctccggtga
    39361 taatcaagcc tcgatagtct ttaccgattt caacatccaa tggtaccgca tgctcaggta
    39421 aaaatggatg tctgccttgc ttgataatga tatgttccga tttattgatt ctaggtgtgc
    39481 ttccattgat ttctcggcta aattttgccc gagcaaagat gatatctaac accgtgatcg
    39541 tttcgatcaa taaatcgatc acttcttcgt tttctgcgat agcaccagtc aatgccgcca
    39601 ggacttgata ttcttcactg atttcttcag cttttaacaa ctgatagtgt tcattcaatt
    39661 tagaaatcac agttggttca ataaaaaccg tcgttctttt atttgattca tcgataatcg
    39721 ttccatctat tttattttta tagctggctt tgataggaat cgtatagtat tcgccttttt
    39781 gaacaatcat tgcttcttgg atcatttctt tgtttttcgg atgacgcaag aatttcagta
    39841 attttgactg gatttctttt tcgattagtt gtaattgttt gcgtacttta cgcaaattac
    39901 gtgacgcgtc gtcactgact ttattatttt ttattttctg gtcaatcaac tcttctacat
    39961 ttatcaaatc aggaagatgt ttgctataag caaacaacaa gggtgtctgg tattgattct
    40021 tatcaaaaaa ctttgtgatc atccgactgc ttctaagaaa atccgcatat tcgatcaaat
    40081 cggttggctg cagaatcaac ccttttttga cttgttctgt cagtgcatcg atcctcggca
    40141 accccataaa tggaacatgc tgactgcttt ctaagatcaa gcgtgcttct cttgtttctt
    40201 cttgacgatc caagacagtt tgtaggtttg tcgagaccgt catatcgctg attcgttttt
    40261 tgctatagtt tccaattgct cttgcttgga tttccttttt gatccgatca aattgtaatt
    40321 gactaatcat ttcgttgtcc atattctctc cttttcttga agagatacct gtcccaaaat
    40381 aaataagggc ctagagataa ataaaaggat agaacacagc ttaaaaaagt catgtcctat
    40441 ccttattaga atacaaagat attgttttcc tgacaggtac cgtttcataa gcacaccaaa
    40501 taaactttgt ttattggcta ttcgacttac tgattagata ccagctacac tcacaaaaca
    40561 taccccattc ttctaggtct tatttatttt ccacttaact atagcaagac acattttggt
    40621 tgtcaaactt tagtatgttt tatagattta caccattaat gaatagacac ctaccgcgat
    40681 aattgctccg atcattggac ctgcgattgg tacccatgaa tatgcccaat ctgaagttcc
    40741 tttattagct attggcaata ccgcatgtgc taatcgagga ccaaagtccc gagcagggtt
    40801 gattgcatat cctgttggcc ctcctaatga aagaccgatg gctaagatca atccacctac
    40861 agcgaatacg ttcgttccag gtgcaaattc gttttgtcca aaagctagca acccaagaac
    40921 taatacaaat gtaccaatta attctgtgat cacatttgct ggataattcc gtatagcagg
    40981 acctgttgca aacgttccta aaatcgcgct ttcatctttc gttgcattcc aatgtggcaa
    41041 ataagaaagc caaacaagaa tggcccctgc aaaagctcct aaaacttgcg caatgatgaa
    41101 aggaacgaca agattccaac taattgcccc tgtcatcgcc atagctagag agactgcagg
    41161 attcaaatga gctgggccca tgaatccaga aatatagaca gccattgtta cagcgagtcc
    41221 ccaaccaaat gcgatgacaa tccagccaga agcctgtgct ttacttttgt ttaaattcac
    41281 agccgcacac acaccatctc caagcaaaac taggatcagt gtcccaataa actcccccat
    41341 gatttgagtc atatcactgt tcatttattt ctcccccttt agttcccgca gatctgattc
    41401 tgcaatcaat gcttctaaac gtttagtctg ttgcgccttc tcctcttctg tccattcaaa
    41461 atatccagca attgcatcga tcacaggttg cttgatctca tcaagctgat ctcgttcaaa
    41521 caacagatga tttgtacgac gaatgagata atcgcctggg gccaaaacca tttcttcttc
    41581 taaaccataa cgtaaccgag ctgactcagc gagactcaaa ccaggataag gtgccatttc
    41641 ttttgctaat tcaaagatac gtcgggcatt agtcccgtaa aaatcagcga tataagtagc
    41701 atcttcttcc tctaaaccgg ctgctactcc ttcttttgct aattctgtca ctgtttcttc
    41761 taatttagtt ggatcgaagt ttccacctga aatctgatat tttttagagt cgatttcttt
    41821 cgtctctatt ccgtattctt cttttaataa ttggcgtatc aatcgcaaag ctccttctgc
    41881 catcttacgg taatcggtga ttttcccacc agataaagtc agcaaaccat ctggttctct
    41941 ttctaaagaa ctacctctgg aaatcgtaga aggtgctttt tcatcacggc tgttttccaa
    42001 atggttcaac acgtcttcta cttcagcacg agaaactttg ttttccttat attcacttac
    42061 tgtatcgaca actttattga agctcttgtc tgaaatcgat ccattatctc caccattgta
    42121 atcagaacca gaattaccaa tcaacagtgg acgaagtcct gcccagcttg cttcgatatc
    42181 attcaatgtg atatttgctt ctggatagcg atgattgatc acatccaata gataatctac
    42241 atcttcttgt gtgactttcg gatccgtaaa atctccttgg taatccgtat ctgtcgtacc
    42301 aaagtaagtc ttgttttctc ttggaatagc aaaaaccatc cgcccatctt gctttcctgt
    42361 atcgaagtat gtgggttgcg gtacaggcag ttttttcgca tctacaacta aatggatccc
    42421 tttagttgga cgcattttag gagagactgg acgcgtaaaa ttcaagtttc gtactttatc
    42481 tacccaagga ccactcgtat tgatcactaa ttttgctttg atttcgatca cttcatctgt
    42541 cagcaggtca cgagctttga cgccaacgat ttgatcgcca tcatataaaa agccaaccgc
    42601 tttcatttta cttactagat aagccccatc ttcggcagcc tttttgatat tatcaatcac
    42661 taaacgggca tcattgttgc ggaaatctag atagacaccc gcgcctttta gcccttcttt
    42721 tttcaaaaac ggttctcttt ccaatacttc ttctggtgtc agcgtataat tctcatattt
    42781 ggttcctgtc acatttgcca gtttgtcata aaggtccatt gctactttga ccgagaacat
    42841 attgaaggtt gttgctcctt cgccctcata gattggcaaa agcattggat ctggttttgg
    42901 gatgtgtggg gcaatacttt gtacgactgc acgttcacca actgtgtcag ctactacttc
    42961 cacatcaaat gtcttcagat aacgaatacc gccatgaaca agtttggtcg agcgagagga
    43021 agtcccttct gcaaaatcct gcatttcgat caatcctgtt ttgattcctg atgctgctga
    43081 ctggactgcc acaccggcac cagtgattcc gccaccgatg atcaacagat ccaattcttc
    43141 ttgctgcatt ttttgaatgc tatcttgtct tgtcttgttt gaaaacatat ggatttcctc
    43201 cttattcaaa tgcttgggta gcttttactg cttttttcca accgttgtaa agtttttctc
    43261 ggcgctcttc ctccatttga acttcaaata gcttgccagc ttcataaaat tcgcggatct
    43321 cgtctgtatc tttccaataa ccgacagcta atcctgctaa aaatgctgcc cctagcgccg
    43381 ttgtttccaa gttttctgct cgttggatcg gtacattcaa gatatctgtt tggaattgca
    43441 tcagatattc attgtttgct gcaccgccat ctactttcaa tacaggaatc ttgattccag
    43501 tgtcatcttg catcgtatcg atgatatctc tcacttgata agcaatcgac tgtaaagtag
    43561 ctttaatgat atcttctttt gtcgtaccac gtgtcaagcc aaacatagcc cctcgtgctg
    43621 cctgatccca ataaggagca cctagcccaa cgaatgcagg aacaacataa acctcatctt
    43681 cgcttgtaga gcgtttcgct gcgtcttctg aatcgctagc tttttgcaac atttgaagtc
    43741 catctctcag ccattgaatc gaagaaccag ccacaaaaat acttccttct aaagcatagt
    43801 aaacctttcc atttatgccg taaccaattg tcgtcaataa attatttttg gataattgcg
    43861 gtttttcacc ggtattcatg acaataaatg aacctgtacc ataagtattc ttgaccatgc
    43921 ctggttcgaa tgccatttgt ccgaataatg cggcttgctg gtctcctgcc atccctgaaa
    43981 ttggtgcttc gcttccataa aaatgataac cttgcgtata accataaact tctgagttag
    44041 aagtgacttt tggtaacatc actcgaggaa tatttagtaa atctaaaatc tcctgatccc
    44101 aatctagctg atggatattg aacaacatcg tccgactggc attcgagtaa tcagtaacat
    44161 gtgcttgtcc atcggtcagt ttccatacta accaagaatc gatcgttcca aacatcaatt
    44221 cgcctttttc agctcgttct tgcgcgcctt ctacatgatc aagaatccag cgtatcttcg
    44281 ttgctgagaa ataggcatcg atcactaacc ctgttttttc gtggaaaaat tcttgatagc
    44341 cttcattttt taagttatct gcaattccag ctgactgtct ggattgccaa acaactgcat
    44401 gatagattgg acgtcctgta tctttttccc atattactgt tgtttcacgc tggttcgtta
    44461 tgccaatccc agcaatctga tttggtttga tccctgattc gatgaacgct ccggcaataa
    44521 ctgactgtac agaattccag atttcatttg catcatgttc cacccaactt tcttgcggga
    44581 aatattgcgt gaactctttt tgagaactgc cgatgtgtct tcctttcttg tcaaagataa
    44641 ttgctcgtga gctagttgta ccttggtcaa tcgccatgat atacgttgat tctgtcattg
    44701 tgattccctc cattatatgc aaacgctttc tttaactact cttatcatac tactgtttta
    44761 aaaaaagaaa ctgtcaaaat tttattcttt ttttcttttt ttgacagttt tttattatga
    44821 agctattttt taatcaattc ttttcttttt tcagcgtctc tattcttctt ttcaatcgaa
    44881 taatgtcgta aggtgacgca aattctgaca gataatattc acactgtttt ttgtttctct
    44941 ggcaaaatgt gatcaccaaa tcatattctt taccttcttc ataacttcca atctcaatac
    45001 cgccgattcc cctcagttct ctgatcagat attgttgaaa agcaatacga taaatcggca
    45061 gactttctaa atcgattcca atcactactg gttttgcaat ataaaaatcg atcatcaaaa
    45121 gaacattggc atactggatc atcaggtaac taagctcact atcttcagct cttttcctcg
    45181 gcaattgctg caccgctgtt tcctgtaatt tcgccagtaa ctgtgttaag gaatgcccga
    45241 gcattttctg ctgctgttcc aaaagccgat cacgctcata gacttcgatc tttccaacaa
    45301 agaaaaacca ttcattgttg atctgggaaa tttggtagcc tactgccttt tcttctttga
    45361 ttttcaaacg acgaggacga taatgccata acatcgtttc ccgaatgtaa gtatctaaaa
    45421 cagcggttgg taactttttg ctccgtgtca aatcatactg ataaaatatt tcttcgtcta
    45481 ctatcgaaaa agaaacaaaa aagctgtaaa acatcattgt ttcgtataca ttcagttctg
    45541 ctgctgttcg actaagatgc atcacgatga ttggatcgat tgcttgataa agccggtccg
    45601 actgatagag taatttcttt tctttcaaag ttgcgtacgt acttttttca ttcaatagtc
    45661 tttttttcgt aatcccgagc cagcaagcaa tctgtgcttc tgctgatgcc gtaaacgttg
    45721 tttctaatac acggtccaat cctagaatga acggtctttt ttctggtgta ttttgcaaaa
    45781 aaagcggtcg ctgatcttcc gggatatatt ggaatagttc ataataaaaa tatcgtatct
    45841 gtagctcttc tccgtataat tgaccgtttt tgatttgtaa tccaaattcc tctaagagct
    45901 ggttcaattc tttgatcttt cgaaaaacag aagactcact gatattaaac gctgtcgcta
    45961 atcgaacgat ggatacttgc tgatgttcta ataaatagac gagcatctta aacttcaagc
    46021 tttcctgcaa taaaaacaat agaatttttt ccaaacttac atcttcgtcc aacacaagca
    46081 gcgcctgata ctcatttcgc tgtacttcta cttttttttc catcattcgg ccaatcaatt
    46141 caatatcttc caaatattga tcaaacgagg cttttgacag ttggacatgc tctctcaaac
    46201 cattgataga ggctgttccc ccttgcagaa caaggtttcg caaaatcagg atctgtaact
    46261 gctcttttct ttctaataat gcttcaatct tcataggcag tattcgccac ctttgaccac
    46321 accatatctg gcacacggta ttctggctgg aaaaatagct catgttcttc taactgttca
    46381 aacgtccatc cttcttctac tgcaattgtc agttggtcaa gaaggtggaa catctctttt
    46441 ttgctttgga gctgtgctcc aagaatcttt ttttcagaat caaatagaaa tttgagttta
    46501 actttgcttt gatttattgc tgtaagcttg tagtctacgt atcctgtttc aattttttgg
    46561 ggataaaaaa tgctctcttc ttctgtcaaa cctacgcttc ctaagaaata gccaaaccac
    46621 tgattgccga ctggacgata ggttccctga tcctttgtct gtgagccact aattgtcttg
    46681 ctgacatttc gtgctgtacg gacagcgtta tttactagag aaacatacat tttttcattt
    46741 gttggacgaa aagttacttg gatcgcatcg ccaatcgcat aaacgtcttt ttgagacgtt
    46801 tgcaagtagt catctaccca gatcgttcca tcatcattca atgttaattg ttcttcccac
    46861 atctgattgt cgggacgaga atgattagcc agcaaaacaa gatcatagtt ctcctttctt
    46921 ttttccgtct ctacaatagc ggtttcattt tcggtcaaag acacaacttg ttcttctaaa
    46981 aaaagtgaaa gcccttgatt tttcatttcc tttactaacg gttctgtcat ttcaggatct
    47041 agataacgaa aaagaattga ctttcggctt tcgtaaagat ggatttgttt ttttcttgat
    47101 gccaaccctt cagctatttc gattcctgct tgtcctgcac caataattgc aattttcttt
    47161 gcattcatga tcttttgctg aagagccgtt acgttttgta tctttttaac tgggtgaata
    47221 agcgttgatt ctgcagaaat atttcgaaac ttttgatttg aaccagtcgc tagaatcaaa
    47281 cgatcaaaat ccaatttttt tcctcctgct aaaacgactt ttttttcttt caatcctatt
    47341 actgtctttt ctgtgtaaac atggattcga tagcggtcag tcagttcttc tttcgtgatc
    47401 caagaaagtt gtttttcact ggtaaccttt ccttttaata tcaaattgaa cccgctggga
    47461 atccatccta acttcgattg cttttcaatc aaatatattt cacttgttgg catcaattgg
    47521 cgaagataaa tagccgcatg aatccctgca aacgacccgc cgacaattac aatgttcatc
    47581 tgcattcctc tttcttataa ggtgttctac tgctaacttc tcaatcagaa aacacagtat
    47641 tcataactcg ctttcaacct tatgatacat agcgatgcag cagaatcaac cctctccatc
    47701 ataccgtgtt ctaggtctgc ttctcaataa tgtactagtg gacctaattg aagagtatca
    47761 tttctgaaga gatgtttcaa aaaatgtact cttataaaag aaaaaaactc gccttttacg
    47821 tacctctgtc caaataggaa acagaaaaga acgaaaagac gagttttagc gtgtgtaatg
    47881 taatagttag aatagacaca tcatttattt ttaattcttt aatgcttcaa caactgcttc
    47941 gcctaattga tgagcagatt gaggattttg ccctgtaaga agccgcccat caatttgaac
    48001 cacttctgaa aaagctgctc cagactgata gtttgctcct ttttctttca aagcatcttc
    48061 tgctaagaat ggtacttcat tcgttgtacc atttgcttcc tcttcttcat tactgaaccc
    48121 agtcactgta cgtccagcta aaatagattt tccagactca tctgtaactg gcaacaatcc
    48181 tacaacaccg tgacaaacag ctgagaccag cccttcattt cgatagattt gtgaagcgac
    48241 tttcccaaga tctattgctt ctggaaaatc ccacattgtt ccgtggccac cagcataata
    48301 aaccgctgca taatcatttg catccacatc atcaggacgt aaggtatttc ccaaggcccg
    48361 atttctgaaa tcttcatctt cataataggc ccaatcgatt tcatccatat tcaaaacact
    48421 ttgcggttct aaaggtacat atccgccttt aggactgaca aaatctgcat cgatcccatt
    48481 ttttactaat acatcataaa aatgagtcag ttcacttaac cacaaacctg taggacgctc
    48541 gatcttttcg tacttttcta catttgttaa tacgatcaat actttcattt tcccatcctc
    48601 tttctataaa aattgcgtta ttgataacgt gctttcaaga aattatataa tgggcttggc
    48661 aaataaagct ctttatatgc tttttcaaaa ggtttcgtta caaattcatc ctcacggttt
    48721 tccaataatt tctctgccca gtcaggatcg acgatcattt gctgtccaat tgctgcaagt
    48781 tctgcatatt tcaatacctg ctctacatct tcgcgattgc ggatcccacc gacaccaact
    48841 aaagggatct ttccttgaat cgtgttatgg accacttcaa gaatcgattt atcgttgtat
    48901 ttatcagaac gagctattcg atcatacata tttaatgaaa catgcagata atctagtttt
    48961 gactcacgta atcgttcaag aagccagatc gtgtcttcaa aacggatacc tggtgtttca
    49021 tattcttctg gtgagaaacg ataccctacg atgaatggtt ttttagcata ttgttcaacc
    49081 gctgagaaaa ccgttgttaa taattcttca ataaaacgat aacgattttc caagctaccg
    49141 ccccattgat cctctcgtct attcgaatgc ggagagaaaa attgttggat caaatacgta
    49201 tttgctccat gcaactcgat tccatcaaat cctgattcaa tcgctctacg tgtggctttg
    49261 ccaaatgctt ggattgtttc aacgatttct tcttcactca ttgctcgtgg tgtttccgca
    49321 tcaggacgtt ttgctgcaac tgcacttgca gatacaggct gttctccaga taaagttgct
    49381 cgacttgtca ttcgtccacc gtggaaaatc tgaataatcg cttttgcgcc ttctccttgg
    49441 attgctttcg ctagctcact taatcgagga atcatttcat catgagcgat gctgagttca
    49501 cctggccagc cttttccgat atcttggaca tttgcagcac cagtaataac agcaccaaga
    49561 cctttagaac gttgtttata ataagtgatc tcatcttcgg tgatcactcc attgaaaaag
    49621 ctgagttgtg tcgtcatagg cgacagcatc aatcggttct tcaattgaac tcctgaaggt
    49681 aaagtaattg attgatcaaa ttgtgacatt gtcattcctc ccataattcg ctctgattaa
    49741 cctatcgaga atcatctatc attaaaccac tcgattagtt gtacatgcaa ctaatttgct
    49801 taaaaaattt tatttttttt gtaacttatc tgttgcatca ttcattgtct gggctaattc
    49861 tttacttgct tcatttccca aaactgcttt gtatgactga tgaagttctt cccagctacc
    49921 atcgacttcc ttagcaaatt ggcgtccttg ttctgtaaga taaactaatg acaagcgacc
    49981 ttcgctaact gttttgacgt atcctttata ttctaatttt tcaacaaaac gagcaatcgt
    50041 tgatggggcg gaatagagca tttgtgcaat atctttttgt ggtattccat ctttttcttt
    50101 taatatcaat aaaataaaac cataagttgg tgccagacct gtccttctaa acgcttcatc
    50161 agctaattta ttcaacatgc gatctagctt tttcacgcta aagaaaagac attcatctaa
    50221 cgctttttca attggctttt ccatttcatc ccctccattg gcgtacatat catagtatga
    50281 tttttatttt ttgtcaaaaa acacggaata atgtccgcct cctctgtcta gatttgaaaa
    50341 aaagaagtag ccatcttcaa agaatttcgg cttgttttcg acaaaactcc ttctggaaca
    50401 ccgtgaatca gaggttgtga aaaagtcgtt tagttttgag tatgaagaaa aattttgtga
    50461 aaatggcttt ccacattttt gcataaattt ggcttaatac cgaaaaactg gcttttgaac
    50521 accgtttata tcagaggttg tgaaaaagcc gtcctgcatc aagtaataag aacagccaaa
    50581 caaaaatagt tcctcatatt ttgtcgtttt ttgagctaat gccgatggtc agctgattgt
    50641 acaccgttta ttgagaggtc gtgagcctgc cgttgaactc cgagtcacaa ggagcaattt
    50701 caaaaaacag cttctcatgt tttatgacta tggtgacttg tgatcgagga gttggcagga
    50761 gaatactgtt tattcgtaaa gaaggggctg tgacaagact tttgtcacag tcccttattt
    50821 ccttttatta taggatttcg ccatttgatt ggatgacttg tctgtaccaa tcaaatgatt
    50881 ttttctttaa ccgtttcttt gtgccattcc cttcgtcatc ttgatcaaca tagatatatc
    50941 cataacgttt tgacatttgt gaagtagaag cgctgacgat atcaatgcag ccccacgacg
    51001 tataaccaaa taaatctact ccatctttga tagcttcctt catctgctca atatgctgct
    51061 tcaaatagtc aatgcggtaa tcgtcttgaa cggttccatc ttcttctact ttgtctatag
    51121 ctccgagtcc gttttcagct atgaacagtg gtttttgata cctatcatat aattgattca
    51181 aagcaattct caaaccctta ggatcaatct gccagcccca ttcacttgat ggaagatacg
    51241 gatttttaat tcctccagtt attaagtttc cttggacccc ttcccaattt tctggatgag
    51301 cactgactgc actagacatg tagtagctaa aagaaacaaa atcaacaggg taggctgcta
    51361 agatttcttc atcacctact tctattttta agttgacacc tttttcttca aacattcgtt
    51421 gcgtatacgc tggataatat cctcttgctt gaacatcact aaagaacaaa gaagttcttt
    51481 gctgctcaat tgttttttga atatcatccg gatcacaaga atacggaaca agaagctgat
    51541 agctgatcat acaaccgact tgtgaacctt tgataatttc atgacaagct tttgtagcta
    51601 aagcacttgc tataaactga tggtgtgcac cttggtattt cgcttgttcc aaatggggat
    51661 ggttttcttc aattactcct acgctaacaa aagggtgatg ttttacacag ttgatctcat
    51721 tgaaagtcat ccaatatttt actttatttt tatagcgttt gaatactgtt tcagcgaaac
    51781 gaacgtaaaa ctgaataagc tttcgattag gccatccacc atattctgta accaaatata
    51841 acggcatttc ataatgggaa agagaaacga ctggctcaat cccatatttt agacattcgt
    51901 caaacacttg atcataaaaa aataatcccg cttcattggg tgtttcttca tcaccatgag
    51961 gaaaaattct tgtccatgcg atagacatcc gatagcattt aaaacccatt tcagcaaata
    52021 aacggatgtc ttctttaaag tgatgataga aatcatttcc gtgtctttta ggataataat
    52081 acttgctgtt gggatcctgc gccgctttta cttgctgatg cgtcatcata tgccattgat
    52141 ctgtccattt ttctttaggt aaatcgctgt cgaatgtata cacatcagac acagataatc
    52201 ctttttcatc tacatcccat gcaccttcac attgattggc cgctgtcgct ccgccccata
    52261 aaaatccttc tggaaatttt ttcatatcga tccccctaaa cttgctagtt ttcttgtttg
    52321 attatttttc ttatgactag taatgatatt tttgaatcta ctactatttg taacaataac
    52381 cattgtggtc ggatcatatc cctctttgat taattcttgc aaatctactt ccatcaataa
    52441 atcgccttta cgtacttttt ttccatcaga tactgcactt tgaaagtatt tgccatttaa
    52501 attcactgta tcaataccga tatggatcag tatctctgct ccttcttcac tgactacccc
    52561 aattgcatgt ttcgttggaa aaactgttga aacttccccg tttacagaac tgtagatttt
    52621 tccgtccgtt ggaatgatcg caaacccttc tcctaaagat ccactagcaa atgttggatc
    52681 gtttacttca gataaatcaa ttatttcacc tgctgcagga gtacttaaca ctatatcctt
    52741 tgaggattct tcttcgattt catccttgta gccgaaaaga aaagttagca tacaggaact
    52801 gatcatcgct aagaaataac tagcaactag ccaaacaaat ccttcaccaa tataaatcgg
    52861 gaaagacaaa atacttcttg tagcaactgc caaagcaccg gctcctgcgg caccagctac
    52921 tccaccaaat atagctccac atatacaagc aatgtaaaat ggtcgtttat atttaagagt
    52981 cacaccataa acagcaggtt cagtgattcc aaataatgct gtgataaatg cagataaaga
    53041 taaacttttt actttcttat ttttcgtttt caaaaatacc ccaagtactg ctcctgcttg
    53101 cgcagctacg gcagtcatac atgctggacc tagcgtatca cgaccgtaga aagaaagatt
    53161 gttggtcatt actggtacaa gtccccaatg taacccaaaa atcactaaca cttgccaaaa
    53221 tccgccgata acagcaccag ataaaacagg gctaaagtta taaacagcta aatatccagc
    53281 tgcaatcagc tgacttgcat aatctgcaat tggacctaca actaataaaa taattgggac
    53341 catcacgatg atacaaatga atggtgtcaa taaatttcga atactttcgt gcaagctttt
    53401 gcgaatctta ggctcaatat aagaaagaac ccatacagct aaaattgctg gaataaccgt
    53461 acttgtatac cttgctagaa tcacgggcat ccctagaaat cgcaaggtta tgctatcact
    53521 atatgcactg acaatcgtag gataaacgag agctgctgca ataaccatag cgatgaaacg
    53581 atctgtattg aacttttttg cagcagtata tgccaaaaat ataggcaaga aatagaaaaa
    53641 tgcatcagct gctgcattca aaatgatata agttcctgat tcagtagtta ataaattcaa
    53701 actcgtacat aaggcgagta ctcctttgat caaaccactt cctgccaaga cgcctaaagt
    53761 cggggcaaaa acagcggcga tcatgtctat aaaagagttt aaaatgcctt ttttctcagt
    53821 tcctctcttt ccactagatg catcatcttc tagtttcatt tgtttggata atacgtcata
    53881 cacttcattt actgcatttc ctactacgac ttgaaacatt cctccagctt cgactacagt
    53941 gatcacacct tctagttgct ctaccttctc cttatctgcc ttcttattat cttttagggt
    54001 aaagcgtaac cttgttgcac aatggtaaac attgctgaca ttttcttcgc ctccgacaaa
    54061 tcggacaata tctttcgcta attgtgaata gtccattttt acttccccct tgttaattaa
    54121 tgccgtagca atccttctta caagataagt atagttctta gaaaacggtt tctccattca
    54181 attagtaccc cttctaatag cgaacgaaac tgtacaatag tgtgtatggt ttacttagcc
    54241 gagcaaatca ctcactgctt gaaagaaaac aagtatatcg tttctcttat agtcaaagga
    54301 gacaaaaaaa acacgcttga tcttcctttg ctgatgtata agtggtatct caagctgata
    54361 ctctgtgatt tttgtttcta cttggctttt gataagacag cacaacaaag tctcggcatt
    54421 taacggaagc ataactaggt cagaactagg agagattagt tgctgaatgg aatctatctt
    54481 tttatggatt tttatttgat tttcttcttt gtagtaatga tcaagcagtt ttgttttctt
    54541 tttttcttca actatggtca gcttttcacg caaaatctga taaatctccc aagattcaaa
    54601 ctcatctaga acactaggta gataaatcaa atcatcccac tcaaaaataa gctcttgctc
    54661 agtagtcaaa attgcatcat attccgttat tttgtttgat tgatttttga aaagatacac
    54721 tggttctatc cggcattctt tgatccacat gttcatactt tgttgaatct gtttttttag
    54781 tgtattcaaa atactaattg gctggttact aacaatcagt atctcccctt gttttcgaaa
    54841 aggattcaac gcttcggcaa gatacaaaac aaaataagcg ctttcagcta aattgggacg
    54901 taattgaaaa tgtattggga agaaacgccg aattaaataa atttctaaag gataacggga
    54961 gatgatcttt tgtacaaaat gattcatggt attatgtccg gcatccatcc tcgttttcat
    55021 ttgtttgata tgggttagca aaaattctgt ttcatggaac aataacgaaa caggaagatc
    55081 taaaaaacga ataatcgttt gctcaaatgc tcttagattc ttctctattt ctttgttttt
    55141 ttcatcatta atcatcaaat aatttaactc taatagtcga ttttcaattg cttgtttttc
    55201 ttgattggaa aaagaatagg gtagttctga tgataacttt tttgtgaggg tctctaccat
    55261 cggaataaat aatgtatacc tgtttgtttt ttctaaaagt tcttctcttc gaagaatggt
    55321 caaaacgaga taccgagaaa atcgtatgaa gtcctctcct gaaacaatat aattatatga
    55381 tataagaacc tcttttaatg tcttttggac agtcggcatg atattggaaa aaattgtact
    55441 gatttgttga ggaaaccttg cgtgttggat caccgtttct gttccaacaa gagataagaa
    55501 aattcttttt gaattttctt cagcaatgat ttttagtcct tttgtcgacg aaacttccag
    55561 ttctaattta ggattgcgct cgatccaacg caaaatcgtt tttatttgta atgatacggc
    55621 tgtttttgaa agaaagaaaa tgtctgctat cttttgcata ctgacatacc ctttttgaaa
    55681 caataagtac gtcacaatag ttgaagctcg gaaatccatg ctggaataga ttttatgttt
    55741 cgtcacctct tgtatgattt gctgtttagt ttcagattca attgattcta aaaaataacc
    55801 tgaacgttta tttgactgga taatgatttt cttctcgtag atagcaagca tatttttgat
    55861 ttcagtttgg atcgttttct tgttggtacc taaagcttca gctaattctt cgcttgttat
    55921 ccaatgattc ttatttctta atactacaag aatttggagt tgtcgtttat ttaagtccat
    55981 ttgcttacac ctcctctttg ttataaacat acaggaaaaa cctctcaaat gacaatagtc
    56041 acttgcagag gtttaaaaat catttgaaga aagatctata ttcaaggttt ttaccattag
    56101 actggataat ttgtttataa tattcaaaac tatctttttt caatctccta aagcttccgc
    56161 tcccatcatt ttgtctatcc acataaataa agccatatcg cttcctcatt tcccctgttc
    56221 ctgccgatac gatatcgatt ggtccccacc ataagtaacc aatgatttgg caaccatctt
    56281 ttattgcctc agcaatttcc tgaagatgta tttttagata ctcacaacgt tttggatcgt
    56341 ggattcgatt caattcatct ggtgcttcat ctagtccaat gccattttca actatgaata
    56401 atggtaattc ataacggtct gtcaattcat tcatgacata acgaaaccct agaggatcaa
    56461 ttggccaact ccaaggttcg ggagattttt ccttcaaaaa gggattatcg aaaccatttg
    56521 ctccgccagt atctacgcgc atttctgctt cttttttata gacagcgcta cgataataac
    56581 taaatgcaat ataatctgcc gtgttagctt gcaagcactg ttcgtctcca tctaacatta
    56641 ctggtgcaca gtcttcttcc ttccatgtcc tgtaaatata agctggataa tgccctcggc
    56701 acatgacatc ggagaaaaac catgaattgc gtttaaattg cagtgaacca aatacattct
    56761 ctggatcaca gtcatatgca taagtcgcta atgcagaaaa gctacacata atacccatct
    56821 tagcatttgg atcgattttc tttaataatt gagtagcacg ggcgttcgct agaaacatat
    56881 gatgacaggc ttgataaatc actttttttg ttagtgtagc aatgggttca agtttatctc
    56941 tagcagggaa tgtaaccaat ccagcagctg cataaggcat acgaaaagca ttattgatct
    57001 cattaaaggt catccaatat ttcactttcc cttggtagcg ttcaaagacg gtctgcgcat
    57061 aaaattcaaa aaagtcgatt aattttcgat tttgccaccc cccatactct cctaccaatg
    57121 ctaagggggt ttcataatga ctaagagtaa ttactggctc gatatcatat cgatttaatg
    57181 tattgattag tctgtcataa aatacgagac cagcctcatt tggcttctgt tcgtctcctc
    57241 ttggaaatat tcgtgcccat gagatgcttg ttcgaaaagc ttttaaacct aactccttca
    57301 gtaaacgaat atcctcttca aatcgatgat aaaaatcaat cgcttcatga gaaagataat
    57361 ggagtgattc gtctaaagca atctcccaaa tctttttttc ttcattccac tgaatactag
    57421 gatgctggtt catgatcccg ataagcgtat ctgtcacatt aggtaatttg ccgtcttcca
    57481 accatgcacc ttcacattga ttagcagcta ctgctccgcc ccataaaaaa ttttctggaa
    57541 atatttcctg atccataact atctctcctc gctatcaaca atttcttact tgaagtatag
    57601 ctcgattcat caaaacaaga tattctaact atttcggcag aagagaagaa aaaaattgaa
    57661 tgctactctt catttttaat atttatatat aacaaataca taagacgatc cccgaaagaa
    57721 aacactcgtt aaccatctaa gcaaacgatt tattttactt ccaacacaaa tgcttcataa
    57781 ggtcgtaaat caactttgcc gtctggtaac tgtttcagag gataatttga cacaataacc
    57841 cttaaagctt cacgtggaat agtgaacgtc tgcttttcac tggacatatt acaaataacg
    57901 agccattgct ggtcttcata tatgcgagaa taggcaaaga catgctcagg cgtcttttcc
    57961 actaattcat agtctcccca gacgatgatg tcatgttttc tacgcaaatc gatcaatttc
    58021 ttgtacatat aaaaaacaga atcttgatct gctaacgctt cttctgcatt gatttcttta
    58081 taatttggat tgactcgaag ccatggaatt ccagtagtaa acccagcatg ttcacgggcg
    58141 ttccattgca taggcgtcct agcattgtct cttcctttcg ccttgattga ttccaagatt
    58201 tcctcttttg taaatccaga agaaatcctt tcgttataca tattgattgt ctcaatatct
    58261 tttgcttccg cgatatcatc gattgggcaa ttcgtcatgc ctaactcttc tccttgatag
    58321 atataagggg tgcctttcat catatggagc aagatagcaa acatcttggc actttctttt
    58381 cgatacacat cgtcatttcc ccaacgagaa acaattcgcg gaagatcgtg attattccaa
    58441 aataaactat tccatccttc atcacctaaa gatgtttgcc atttggataa tacttttttc
    58501 agttcagaga tactcaaggg tttcaaatcc catttgtctt tgccttcttg ctgatctaat
    58561 cctatgtgtt cgaattggaa gaccatggat aattcatttc ttttaggatt ggaataaagt
    58621 ttagcgattt cggtagttgc tccccatgtt tcgccaacag tcatcagatt tttgtcacca
    58681 aaagttgctt gattcatttc ctgaagatac tcatgcagtt taggtccatt acttgtgatt
    58741 tctttatccg gttctttgcc aatcatatcg atcacgtcca tacgaaagcc cccaatacct
    58801 ttatcgatcc agaaattcat catttgataa atctcttggc gaacctgttt atttttccaa
    58861 ttcaaatcag gttgacgctt gctatacaag tgcagaaaat attgccccgt tttttcatcc
    58921 aactgccaag cagaaccact gaatattgag cgcaatctat taggctcttt tccattgacc
    58981 ggatcacgcc aaatataata gtcccgataa ggattttctt tatttttacg ggcctcaatg
    59041 aaccacggat gttcatcaga agtatgattc accaccagat ccatgatgat acggatattt
    59101 cttttctttg cttcttcaat cagttcttcc atttcttcca tcgtaccgaa ttctgccatg
    59161 attgcttgat aattactgat atcataccca ttgtcatcat tcggagactc gtatactgga
    59221 gaaagccaaa ttgcatcaat acctaaatac gccagataat ccaacctgga aataatcccc
    59281 cgcaaatctc caataccatc ttgatttgaa tcttgaaaac ttcttggata gatttgataa
    59341 acaactgaat ggtgccacca tttttgttcc atgattttcc tcctataaat ggatgtttct
    59401 attttttgct taatcattta ttttagtctc tctcactaaa aattgtaacg ctttcaaata
    59461 gctattgcac cttgttatcg gtaacagaat aaaacaaaaa aacagctgag gaaattccct
    59521 caactgtttt ttgaaaggat tgatttatgc agggaagaat gctgatttca caacttcttt
    59581 ataaacggtg ttcactcagc tgtcccttgg tattagctca aaaaacggca aaatataaga
    59641 aactattttt tcgttttttt ctctaatact caggccagaa cgctgatttc acaacctctt
    59701 tatttcacat tcaatatcca catgaatccc acaaatacaa agaacagacc atacatgatt
    59761 ggagatactt cttttcctct tttagctgct aacatggtaa ttggatagaa gataaaacct
    59821 aatgcaatcc catctgaaat actataagtc aaaggcatgc cgatcaagat caagaatgaa
    59881 gggatcgcaa tctctaagtt tccccattcg atttgtcgca aagattgtgc catcaatact
    59941 cctaccataa tcaatgctgg tgcagttact tgtgaagtaa caactgatag taatggagaa
    60001 aagaacaagc ctaacaagaa gaaaatccct gtagtaatag ctgtgatacc tgaacgtcct
    60061 ccaacggcga taccagctga tgattctaca aatgcaccaa caggagaagt accaaataag
    60121 gaacccgcaa gcatagctgt tgaatcagaa gctaaagctt tccctacacg aggcatcttg
    60181 ttgtctttca tgaaacctgc ttggtttgct aatccaacta aagttcctgc tgtatcaaag
    60241 aaagtcacaa gcaagaatgt cagcactacg acccacattt gaagagaatt gatgtcccct
    60301 acatgtttta atgcaactaa aaatgttggt ttcaaacttg gtgctgcggc aacaatttca
    60361 gaaggcattg gaatcaaacc tgtgaccaga cctaaaatcg ttgtagctgc catcccgatg
    60421 aagatgccac ctggtacacg ccgaacaagc aagatagcag ttacgactaa tccaaaaatc
    60481 gtcaaccaag tagaaccaac gttgagtgat cctaatccta ctaatgtaga ttcattcgaa
    60541 acgatgatcc caccttcgct cagaccaagg aaagcgataa atagaccgat accgccagaa
    60601 atcgcatatt tcaaatctgc tgggatcgca tcaatgatca tttcccgcag cttgaagatt
    60661 gtgatcaaaa taaaaatcaa agaagcaacg aatacgccgg ctaatgctgt ttcccatgga
    60721 atccccattc ctaaacaaac agaataagca aaaaaagcat tgatcccaag agcaggtgcc
    60781 gttccaattg gataacgggc taataccccc attaaaacac agccgatcgc actggctaat
    60841 gcagtcgcag taaacactgc tccttcatcc attccagaag cacctaatac agttggattt
    60901 acaaataaga tataagccat tgagataaat gttgtaaatc ctgccagtac ctcacgtttt
    60961 accgtggtgt tcaatttttc tatttcgaag taggaaagta ttttttcctt catcttccat
    61021 ccccctaaat ccgaacatta taaataaagt ccgttaaaat ttcgatttat taataaaaca
    61081 acgtgtttta tcatatacta aaacaaaaca taagtaaaca aaaaattcgg attttaagca
    61141 aaatccgaac gttccatctg attaaatccc tttatctcaa agttcatgaa cattcacttt
    61201 ggattacaag aatttcttta ttgtgttaat aaagtttctt cattctagtc tcaaaaatca
    61261 atagtgtgat ttgattttac catttcgttt ctgttcttct ttgatgaatt cttttgtatc
    61321 gacaggattc agattattta gtccgccaaa acctgtatcg accatttttc cccagccttt
    61381 tgtcttcttt tttcctgatt tgagattctt tgctcgaagc ttctcactat gttttgctcg
    61441 ccgatacttc aaataacctt ctaatcttcc cattagatcc actgtttttc ctccttttta
    61501 ttcaatcaga cgactcagct tttcctataa caaaataatt gccttcaggg tcagaaaaat
    61561 tgaaagtcaa gatgccattg ttatctgtga tttctcctgg ttcttccatg ttctcgtaga
    61621 tagtttcaaa ttcatccgta aaaaatacta aagaaggcgg tggtcctaat acctctggtg
    61681 aaaacttctg cacaaatact tttgggaata cgcctaattc taattctttt gagatgctga
    61741 gtacaatact cttaaattct tctggcaatt cgattgtttc agaaatttct gcaccaattt
    61801 tttctacaaa gaatcggcaa atcatctcta cgtcattgac ataaagcatc acacgtgttt
    61861 tttgtatcat catttgaccc ttctttctat ttgattttct ttcctgtcta taaactgatt
    61921 ccattatatc acgaaagcgc aaacaccttg tgtttgatac tattcaagaa aaataaagca
    61981 atagtttcta ggattgcttt cctccacaaa ctttttttac aaaaaaaaaa cggcaatgaa
    62041 tgccgctctt cttatttcga ttcttttata attctgcttc tgattcatct ttggttagtg
    62101 tgtgtctaac actagttacg ccaaatgttt gatcgatttt ttccttcaac gcttcgattg
    62161 cctgtgcgcc acgtgccgct tgttcagcat tgatggattc aatgaccagc accgctgctt
    62221 gtgtttcttc cgtcagcatc gttctttggg cttcacgcca gttgagacag cgacagatcg
    62281 ctccttgttc atcatagtag atgatttctt ccggaagtgc cggagcatcg gaatctgcac
    62341 ctaaaggcag gaatgattcg ccaccttggg cttttcctaa atgcagattt cctgcgatct
    62401 tttcgatatc ttctccgccg caaggtacgc caaaagacaa ggaaatacta ttatagatat
    62461 ctacaagcgg attgattggg aaaaattccc gttcttgatt tgcacgtttc agtaaagctt
    62521 caatagaaga acgtgcacct tttttagtct tgaatgtggt aaatgcctga cgccactgag
    62581 caatgacttc gttttggctg aatgtttctt ctgtaaggta atttcttgct tcttttgctg
    62641 cctcattcaa taattgatga tacgtttctt cactttcttt tgttacgtgg ttatcgatac
    62701 catttacgga taagatttcg atggttgctt caggaaatac ttcccagaaa ttggtatcca
    62761 ctattacttt tttcatctgt tcacacctct tgattagaat aattgcttga tgaatagata
    62821 gtctgtttgg ggatcatctc ccatataaaa aacatgttcg ctgtatttga taaatccttt
    62881 tttacgataa aaagcgagcg caacatcgtt gtgttcccaa acaccgagcc aaatggctgt
    62941 tttttgcttt tcttttgctt tttcaatagc tgtatctagt aaaaatgtac cgataccttg
    63001 atgtttaaat ttttttcgta catagattcg ctcgatttct aaaaaatgat cagccatttc
    63061 ctcagattga ctcgttcctg tatttagttt caggtaaccc gcaggctctt gatcgatact
    63121 cactaggaaa aaatcggttt ctttatcttt tagctcttct gtaagttttt ctagtgcata
    63181 agcttgtgtc aagtaatcag ctaaatgctc cggtgaatta tcttttccaa atgtatctgt
    63241 aaatgtttcg atactaattt gttgtagtaa gtctacatct gaaggcgtca tttttcgaat
    63301 ttcgtattta ttcacggctt cttcctttca atagatcctt ttattgcctt ttttgacaaa
    63361 attccaatct tcgctaacat tcttgcatac tttatttaaa agatattcca attgttttgc
    63421 ttcttcgtca gaaagaccat ttaatgcgac tgcattggag tagttgtttt ctcgaatgat
    63481 gaaaggatag atttctgctc cttttttagt cggatagagt ttcttgattt ttttattttc
    63541 tttatcttcc aaacgttcga tcatcccatt ggattctaat ttcttgattg ctcgggcagt
    63601 cgttgtacga tctactttga tcatttctgc tagtttttct tggatgattc caggattttc
    63661 gcaaatacgt actaaataaa gatactgtcc tcttgttaaa tcgacttctt tgaattcgat
    63721 attgctaata gaatctagcg ctcgggcaat cattccgatg tctcgaagga tttcagccat
    63781 ttcatcccac ctttattttg tttgtaagac tagttcacct ctttttgttg caaatgcaac
    63841 tattttcaat aaaaaaatca agttcttttt taataactag taaagtatat tcttttcttc
    63901 ttttacgaaa aagctcaatc acaatagatc tggtttttgt tttctaaaat aagtaactgt
    63961 ttcttcgttg ttcgcttttc tgatagcttt ggcaactctt ctatactaaa aaatcccatg
    64021 ttggaagttt cattattctc aataaacttg gcctcttcac cgtggatcgc acaagcaaaa
    64081 acaagtttat aatactgaaa aagctgtgga atatcttttt gtttattcgt atcaaaaact
    64141 gctcgcaact gagtagtttc tactgttaat cctgtttctt catagacttc tttacgcaca
    64201 ttttcttcag gagacaatcc tatttcagca aatccaccag gaagtgacca ttctttcgtc
    64261 cgtttatctt cgattagtag gaccttgcca tcttttttga tataggcacg aacatctact
    64321 tttggtgttg gatgtccttc tccaatcgtt gtgagcgctt ttatttcttc gaaagtttct
    64381 tttcctattt cactgatcag ttccaatgaa atcgtccgga tctcctcaaa acgctcttta
    64441 tcaaatacat cttttccata atatagacca gcttgagaaa gtgcgagtag tcttttgtat
    64501 tgagccaact tcttgttcat tctcttccct tcttttttag caaatgtatg actatgtaat
    64561 caagtataga agactggttt aattacggca aataaatata atgaaatctg caataaataa
    64621 aagaatgtta aaaaactcga gaacaaaaga cattcgactt ctctggggct gtgaataaat
    64681 ggcgttcaaa agcttgcatc tgcggtaata agccccacca aacgaaaaat atgacgagct
    64741 attcttgtct ggctgttctt attaattgag gcaggacagc tttttcacaa cctccccact
    64801 aaacggtgtt ctcctaccaa ctcctcggtc acaagtcaca atattcatca aacatgagaa
    64861 gctgtttttt tgaaattgct ccttgtgact cggagctgaa cgacaggctc acgacctctc
    64921 ggtaaacagc gttcaaaagc caatttttcg atattaagcc atttctttgt tacttattgt
    64981 cattgatttc tttttctaat ttatccaata gtggagtgta atccacttga gtatagtctg
    65041 ttacatcaaa ttcatatagt gttcctaact ggaatttgtc atattttcgg tcggcgatga
    65101 tctttttgaa tgcttctttc gtaatatgat tggtcccttt cgttcgatct tccaatacgt
    65161 caccatagtg ataatgatcc atgatatagc tcaaatgacg atctgattca cgatcacgtt
    65221 tgtaccgacg ttgccataac acttcaaagt ctgctgttag gcgaatcgtg atcacctgat
    65281 atccgtatct atctgctaat tcttggagtc gtgctttttg cttatcacta aaaggatact
    65341 cggacacaat cactttcttt cctgcttcca tatacaaatc aagtgctttg taatagaaag
    65401 gataaacttt cgtcctttct tgttccgccc gttcttccaa attgttaaac ccgatggatt
    65461 ctgcatagta ttccttgatt tcatcgagcg tgatggcata catatctgga aatcgttccc
    65521 gtagtttatt cataagatat gtttttcctg taccaggact accagccaga agaatgaaat
    65581 actttttcat ctcatttatt tcctaagtta attggacttt ccaagttcat aaacagtcca
    65641 atcttatgct tgacaatttc ttttactgct tcatttgctg gaatcacatt atggcgaaga
    65701 gacttgttga tttctgtttc actaaaggtt tctttagcta ctttcgtcca gttgactaaa
    65761 agctccgttc caacattgaa tttgcggatc ccgttattga tcaattcagg ataatcttct
    65821 tctttcacac ctgttcctcc atggataact agggggacat caactactgc atcgatttct
    65881 ttcagcaagg gaatgtttac ttctgttttt gatttgaatt gtccatgatt cgtaccgata
    65941 gcaatagcta atgcatccac gcctgtagct tctacaaatt tcactgcgtc ttccggtctt
    66001 gtatatacct tgtcattttc agcgacatgg attccttctt ctgtaccgcc gattgttcca
    66061 agttctcctt ctacggaaac accgtgcgca tgggcatatt ctactactgc ttttgtcttc
    66121 aggatatttt ctttgaaagg cagatgggac ccatcataca tgacagaagt atatccgctg
    66181 tcgattgctt ctttgatatc atcaaagtct cgggcgtggt ctaagtgcaa gactgcatca
    66241 accatttctt cttctgcaat agctgtcatt acattgacta acacatgcat gccgatatat
    66301 ttagcggtat cgacacttgt ttgaataatg atcggcgaac ccatttcttt tgctgcgcct
    66361 agcatagcag gaagcatttc taggttatgc gtattaaaag ctccaactgt aaaattcaac
    66421 tcttctgctg tttttgttac ttctttcaat gttgtataca tcttttattg ccaccttatc
    66481 tttttatttg tttcctttga tcgttacttg ttttgcaatt tgtcgcatct catccatttt
    66541 gcccatgtag taatcgatcc cttgatcatc accagcacga gcagcatctg cacgcttctg
    66601 gttatagagg ctcatcagtt ttttataccc atctccgatc gtctgtttat tttccaaact
    66661 cttttctaaa tattggatgg cttgatcgtt cacatacaat tcagaaaatt taagtccaac
    66721 ttgttcataa agtttcgcta atttatgctt atcttgggta gtggaaatct cttgtttcaa
    66781 ttgtgtaatc tctgattgaa tcttttcggt cgcttctggc gatagggctt tttcttcttt
    66841 tgccagaact tttttcggtt ctttttcttt tttcttaaaa aatccaaaca tcattttccc
    66901 tactttcaat taaaatgctt tcaaaactgg gcttaagatc caggcatata agagtgctgc
    66961 ggctactgta tctacatcgg ttgctgtagc attgttgaat cccatcgaat taaagatcgt
    67021 tactagcaaa gcgggcaata atgtaataaa gaaaccatga gcaataccgc caatgatcgc
    67081 tcctcggcgt ccgccaactg cgttgccaaa tatccctgct gtccctccgg caaagaaatt
    67141 ggttagcata ccaggtaaaa tcatcgctaa gccgaacatg ggcaaagtaa acatggcaat
    67201 aatcgtacca atcgttgtcg taatgaaacc taaaatgaca gcatttgggc tataaggaaa
    67261 gaaaactgga caatctaagg cagggatcgc atcaggaact aatttcatag ctatccctcg
    67321 aaatgccggc acgatttcac ctaacagtag acgtacacca gctagcaata catacacacc
    67381 cactacgaat tggatggctt gtaaaaaggc aaacatgata tagttttgat ctcctgataa
    67441 ttcagaagcg aatggttcgc ctgcaaataa aacagtgatg atatatagcg ggaccatcac
    67501 gaccatgaca gacaaataag tatcttgcag aaattcgaaa tgtgtcggca acttgatatc
    67561 ttcgatcgac tttttatttt cgcctttctc accaaaaagc ttagcaacac cggcttcaaa
    67621 taagtacccg atcgtacaaa aatgacctaa agcaatatca tttgatccag tgattttacg
    67681 aatgatcggt tgcgctactg ccggcatagc aatggcgaaa caagctccga taaaaccacc
    67741 gaccaagatc aatacgatcc ctcgcagacc ggcaaaatag ccaaagactg tcgtcatcgt
    67801 tgccatccat aaaattgctt gaccagttaa aaaaatgtac ttccattttg tgaaacgagc
    67861 caaaataata ttgaatacaa aaatggctaa gaacgtcagt gcaatatctc tacctaaacc
    67921 caaatcattc attgcttgac cattgataga ttcaatagaa gggatgatcc cttgcatatg
    67981 aaatccttca gtaaagattt tcccgaaata agttaaactt ccaacgatga tgctcgaacc
    68041 ggcactcaac acttgaaatc ctaggagtgt ctttaacgtg ccagagatga cttgtcctgc
    68101 tgatttcttc tgcagtagta gacccaacat agcaatcaat gcaatggtga tcgatgcctg
    68161 agtcaaaata ttttcgatga taaaattgat aacgcccat
//
LOCUS       DAPBBV010000009        66155 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.009, whole genome shotgun sequence.
ACCESSION   DAPBBV010000009 DAPBBV010000000
VERSION     DAPBBV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 66155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.009"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(165..464)
                     /locus_tag="RD486_000777"
     CDS             complement(165..464)
                     /locus_tag="RD486_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7662531.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            815..1447
                     /locus_tag="RD486_000778"
     CDS             815..1447
                     /locus_tag="RD486_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDT7662532.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            1570..2208
                     /locus_tag="RD486_000779"
     CDS             1570..2208
                     /locus_tag="RD486_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7662533.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(2327..2399)
                     /locus_tag="RD486_000780"
     tRNA            complement(2327..2399)
                     /locus_tag="RD486_000780"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2364..2366),aa:Thr,seq:cgt)
     gene            2520..2762
                     /locus_tag="RD486_000781"
     CDS             2520..2762
                     /locus_tag="RD486_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662534.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            complement(2901..3530)
                     /gene="upp"
                     /locus_tag="RD486_000782"
     CDS             complement(2901..3530)
                     /gene="upp"
                     /locus_tag="RD486_000782"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDT7662535.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(3664..4611)
                     /locus_tag="RD486_000783"
     CDS             complement(3664..4611)
                     /locus_tag="RD486_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7662536.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            complement(4764..6008)
                     /locus_tag="RD486_000784"
     CDS             complement(4764..6008)
                     /locus_tag="RD486_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDT7662537.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            complement(6183..7208)
                     /locus_tag="RD486_000785"
     CDS             complement(6183..7208)
                     /locus_tag="RD486_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDT7662538.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            complement(7230..7409)
                     /locus_tag="RD486_000786"
     CDS             complement(7230..7409)
                     /locus_tag="RD486_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662539.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            complement(7402..8241)
                     /gene="prmC"
                     /locus_tag="RD486_000787"
     CDS             complement(7402..8241)
                     /gene="prmC"
                     /locus_tag="RD486_000787"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDT7662540.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            complement(8234..9307)
                     /gene="prfA"
                     /locus_tag="RD486_000788"
     CDS             complement(8234..9307)
                     /gene="prfA"
                     /locus_tag="RD486_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDT7662541.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            complement(9310..9894)
                     /locus_tag="RD486_000789"
     CDS             complement(9310..9894)
                     /locus_tag="RD486_000789"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDT7662542.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            complement(10000..10469)
                     /locus_tag="RD486_000790"
                     /pseudo
     CDS             complement(10000..10469)
                     /locus_tag="RD486_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            10575..11177
                     /locus_tag="RD486_000791"
     CDS             10575..11177
                     /locus_tag="RD486_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7662543.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            complement(11281..11850)
                     /gene="lepB"
                     /locus_tag="RD486_000792"
     CDS             complement(11281..11850)
                     /gene="lepB"
                     /locus_tag="RD486_000792"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7662544.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(12080..12847)
                     /locus_tag="RD486_000793"
     CDS             complement(12080..12847)
                     /locus_tag="RD486_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662545.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            complement(12844..13323)
                     /locus_tag="RD486_000794"
     CDS             complement(12844..13323)
                     /locus_tag="RD486_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HDT7662546.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            complement(13448..14185)
                     /locus_tag="RD486_000795"
     CDS             complement(13448..14185)
                     /locus_tag="RD486_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HDT7662547.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            14346..15746
                     /locus_tag="RD486_000796"
     CDS             14346..15746
                     /locus_tag="RD486_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDT7662548.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            15969..17321
                     /locus_tag="RD486_000797"
     CDS             15969..17321
                     /locus_tag="RD486_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HDT7662549.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            17314..18012
                     /locus_tag="RD486_000798"
     CDS             17314..18012
                     /locus_tag="RD486_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDT7662550.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(18074..19225)
                     /locus_tag="RD486_000799"
     CDS             complement(18074..19225)
                     /locus_tag="RD486_000799"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDT7662551.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19238..19675)
                     /locus_tag="RD486_000800"
     CDS             complement(19238..19675)
                     /locus_tag="RD486_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7662552.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(19690..21456)
                     /locus_tag="RD486_000801"
     CDS             complement(19690..21456)
                     /locus_tag="RD486_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HDT7662553.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            21720..22397
                     /locus_tag="RD486_000802"
     CDS             21720..22397
                     /locus_tag="RD486_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662554.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            22400..23527
                     /locus_tag="RD486_000803"
     CDS             22400..23527
                     /locus_tag="RD486_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662555.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(23727..24167)
                     /locus_tag="RD486_000804"
     CDS             complement(23727..24167)
                     /locus_tag="RD486_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7662556.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(24178..26211)
                     /locus_tag="RD486_000805"
     CDS             complement(24178..26211)
                     /locus_tag="RD486_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7662557.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(26213..27916)
                     /locus_tag="RD486_000806"
     CDS             complement(26213..27916)
                     /locus_tag="RD486_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7662558.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(28010..28960)
                     /gene="manA"
                     /locus_tag="RD486_000807"
     CDS             complement(28010..28960)
                     /gene="manA"
                     /locus_tag="RD486_000807"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDT7662559.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            complement(28999..30024)
                     /locus_tag="RD486_000808"
     CDS             complement(28999..30024)
                     /locus_tag="RD486_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDT7662560.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(30233..31102)
                     /locus_tag="RD486_000809"
     CDS             complement(30233..31102)
                     /locus_tag="RD486_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HDT7662561.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(31806..33698)
                     /locus_tag="RD486_000810"
     CDS             complement(31806..33698)
                     /locus_tag="RD486_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662562.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(33695..35422)
                     /locus_tag="RD486_000811"
     CDS             complement(33695..35422)
                     /locus_tag="RD486_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662563.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(35438..36088)
                     /locus_tag="RD486_000812"
     CDS             complement(35438..36088)
                     /locus_tag="RD486_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDT7662564.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            36292..36588
                     /locus_tag="RD486_000813"
     CDS             36292..36588
                     /locus_tag="RD486_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7662565.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            36780..37400
                     /locus_tag="RD486_000814"
     CDS             36780..37400
                     /locus_tag="RD486_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDT7662566.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(37492..38658)
                     /locus_tag="RD486_000815"
     CDS             complement(37492..38658)
                     /locus_tag="RD486_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7662567.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(38670..39023)
                     /locus_tag="RD486_000816"
     CDS             complement(38670..39023)
                     /locus_tag="RD486_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDT7662568.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            39151..40173
                     /locus_tag="RD486_000817"
     CDS             39151..40173
                     /locus_tag="RD486_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HDT7662569.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            40192..40353
                     /locus_tag="RD486_000818"
     CDS             40192..40353
                     /locus_tag="RD486_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662570.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(40612..41046)
                     /locus_tag="RD486_000819"
     CDS             complement(40612..41046)
                     /locus_tag="RD486_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662571.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(41156..43015)
                     /locus_tag="RD486_000820"
     CDS             complement(41156..43015)
                     /locus_tag="RD486_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7662572.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(43133..44293)
                     /locus_tag="RD486_000821"
     CDS             complement(43133..44293)
                     /locus_tag="RD486_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDT7662573.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(44600..46024)
                     /gene="araA"
                     /locus_tag="RD486_000822"
     CDS             complement(44600..46024)
                     /gene="araA"
                     /locus_tag="RD486_000822"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDT7662574.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(46040..46738)
                     /locus_tag="RD486_000823"
     CDS             complement(46040..46738)
                     /locus_tag="RD486_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDT7662575.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(46695..48356)
                     /locus_tag="RD486_000824"
     CDS             complement(46695..48356)
                     /locus_tag="RD486_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HDT7662576.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            48574..49974
                     /locus_tag="RD486_000825"
     CDS             48574..49974
                     /locus_tag="RD486_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HDT7662577.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(50226..51305)
                     /locus_tag="RD486_000826"
     CDS             complement(50226..51305)
                     /locus_tag="RD486_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7662578.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(51391..52350)
                     /locus_tag="RD486_000827"
     CDS             complement(51391..52350)
                     /locus_tag="RD486_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDT7662579.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(52362..53873)
                     /locus_tag="RD486_000828"
     CDS             complement(52362..53873)
                     /locus_tag="RD486_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDT7662580.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(53895..54458)
                     /locus_tag="RD486_000829"
     CDS             complement(53895..54458)
                     /locus_tag="RD486_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HDT7662581.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(54464..55327)
                     /locus_tag="RD486_000830"
     CDS             complement(54464..55327)
                     /locus_tag="RD486_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7662582.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(55341..56237)
                     /locus_tag="RD486_000831"
     CDS             complement(55341..56237)
                     /locus_tag="RD486_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7662583.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(56412..57701)
                     /locus_tag="RD486_000832"
     CDS             complement(56412..57701)
                     /locus_tag="RD486_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7662584.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(57673..59190)
                     /locus_tag="RD486_000833"
     CDS             complement(57673..59190)
                     /locus_tag="RD486_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDT7662585.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            59388..60278
                     /locus_tag="RD486_000834"
     CDS             59388..60278
                     /locus_tag="RD486_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HDT7662586.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(60351..61175)
                     /gene="nadE"
                     /locus_tag="RD486_000835"
     CDS             complement(60351..61175)
                     /gene="nadE"
                     /locus_tag="RD486_000835"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDT7662587.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(61187..62659)
                     /locus_tag="RD486_000836"
     CDS             complement(61187..62659)
                     /locus_tag="RD486_000836"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDT7662588.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(63296..63658)
                     /locus_tag="RD486_000837"
     CDS             complement(63296..63658)
                     /locus_tag="RD486_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDT7662589.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            63881..64633
                     /locus_tag="RD486_000838"
     CDS             63881..64633
                     /locus_tag="RD486_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7662590.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(64773..65696)
                     /locus_tag="RD486_000839"
     CDS             complement(64773..65696)
                     /locus_tag="RD486_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7662591.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(65711..65983)
                     /locus_tag="RD486_000840"
     CDS             complement(65711..65983)
                     /locus_tag="RD486_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662592.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        19149 a        13543 c        11484 g        21979 t
ORIGIN      
        1 atactagctg tttttgtgtt aattaaagga taaaatacaa tataaagaaa catctgtttc
       61 tttatttaga ataaaaaaat acagactctg ttcaaataaa tgaacctagc ctgcattatg
      121 agattgacta tactttttaa ttcattgaga tgaataactc gtttttataa atgcccaaaa
      181 gtaatcggtg ccgaagccat tcctcgacct aattcttttt caaattttcc tattgttgat
      241 atctccatat aaaacggtga tactggttta gacaattctc ccctgattgc taacggacgt
      301 aaactacgtt ccaaattatt tatgacttta ggataatact gacctttttc taagcctgtc
      361 tttgcgtcta tcaaaagtat acgttccttt tctttgatct ctggatttaa aacgagatca
      421 tataatttta gtaccatgtt ttctatttct tcacttttag acatcacgat ttcctcccaa
      481 aaatatattt cttcccacta cattctataa acaaagtata cgctacatct agattttttt
      541 aaatcattac tggattgtta aaacctttca atacactgtt atggcaacga tttttatttt
      601 aaaaacattc taaattaaat cagtaaaaat ttttattcta agatttttat tagaattacg
      661 cctaatttgt gtctctcagg gcaattctaa gaacgtttca agagatagcg acactatcgt
      721 tatcgaaaaa ggcgaaaacc tatctcattt tctgctaatg taagttggtt tagcttttgt
      781 taatatgact ttatgaaaat ggaggtaatt aaatatgatt tttcctaaag ttaatgaagc
      841 aagcttgaat aaaggatcct tttttcatat ctatgaaaac gaagattttg aactgtataa
      901 tatcctttca caaaaagagg tcatcgaaaa ccaaataatc tgccatccaa ttatttacaa
      961 atctattttc aagtatgcat tttttgcttc caatgatttt caaagaatgg agattaccga
     1021 ctgtatattc gaaaactgtg atttttcagg ctgtatattg acaaaaagca tgttgcatcg
     1081 cgtgaaattt gtcaattgta aattaacagg tactaaattg atggaaagtt atattgggaa
     1141 cacgttattc gagaattgta aaatggacta tgtaaattta tctggttcaa acataaaaga
     1201 aagtaccttt gagcactctg tcttatcaag cgcagatttt gtagactgtt ccctcactaa
     1261 aataatgttt tctactaatg atttagaaaa tgctagcttt tttgatactg atttaaaaaa
     1321 tatcgattta agtagcaact cctttgaaat gattgaagta cgctcggaac atctaaaaaa
     1381 ttgtacgctt aatcagttgc aagcacttgg ttttgctaga aaatttttac aaataaaagt
     1441 agtataatca aaatgaatat ataagataaa tttttagcaa tacaaatatc cataaaaaaa
     1501 cattgcctat tttaactctt catgtatact gactctatct tcaaaaactg aatagtagga
     1561 gttattatca tgaataacat tttaggaaaa aaaatagaac ttaaaaaagg gatattgggc
     1621 actattgtcg ttgtactcgg tttgttaggg ttgctatttg cgccatccat tattagcatt
     1681 ttttctttaa ctatcactgg atttatagca tttacacttg tttttggtaa aaaagatacg
     1741 aaaaaaatgt tctcgaaacc tgtcgctcct gtcaaaaata tagccaaata tttttttatc
     1801 aatgtagtaa tcagtgccgc agtctcggta tttttgcaac aaattttgaa atggggttta
     1861 acaggcaatc caataaatga ggctttcagc ccgttattat ttattatttt gcctatcatg
     1921 atacttggag aagaattgtt ctcagtgtat tttctcgcta ttttttctag taagttcagc
     1981 attcctgtcg ctagtttctt gtcagcaatc atctttggat ttatccatta cagtacttat
     2041 gataatggaa atattttaca cactgtagca cacatccttt tgatacaagg ggtggcaaga
     2101 ttgttattca accaagctgc cattaaaagc aactcgatca ttacaagttg ggcagttcat
     2161 gtgatatttg atttcacagc tatattgcta gtcgttttat tctcctaaat ttttatagaa
     2221 ataatacatg ctctattgct aagaaagcat actttatttc ctttaaacaa aaagacagat
     2281 gtatcaatgg attaaaaatc cttgatatat ctgtcttctc ttttaatgcc agctataggg
     2341 atcgaaccta cgacctacgc gttacgagtg cgttgctcta ccaactgagc taagctggcc
     2401 ttatccaaaa gaaattatat actctatttg gctgattgta aagagtccga tggaaaatta
     2461 gtttaatttc atgatatttt tcataaaacg tggtataatt gatgtgaaag gcaggtttta
     2521 tgaaaatggc aacttttgga aaatttgata caactatcgt accatcggaa attggtgaaa
     2581 aattcaagat caatactcac gtaatgttca caattcacgg caagtcgcaa actggaacga
     2641 tttcaaagca attgaaaaat tccgctgttg ttgagattga tgaaactgca gaaaatgcga
     2701 acttgatgac gcaaagtaag ggtgtagtaa tcgttaacta caaagaacta aaaaagattt
     2761 gaatttgacc atctctgcat ttttgggatg gtttttttat atgcaaacga aagctgtgaa
     2821 aaagctgttc tgcatcaaac gttaaaaatg accaaaaaag gatgtgacaa aagttgtgtc
     2881 acaccctttt tcgtatttac ttattttgta ccaaacaaac ggtcacccgc atcccctagt
     2941 ccaggaacga tataaccatg ttcattcaat ttttcatcta gagaagctgt atagatgtca
     3001 atatcaggat gcgcttcttg caaagctttt actccctcag gtgctgctac caaacaaaca
     3061 aatttaatgt tcgacgcgcc acgttctttc aatgcatcga ttgccatgat tgctgatccg
     3121 cctgttgcca acattggatc tactacaaac aactgacgtg catcaatgtc ttctggaagt
     3181 ttgacgaaat attcatgtgg ttccaatgtt tcttcatctc gataaagacc gatatgtccc
     3241 actttagcag ctggaatcaa ttccaagata ccgtcaacca ttccaatacc tgcgcgcaag
     3301 attggaataa tcgctacttt tttaccagac aacgtttttt gtgttgtttc agtgatcggt
     3361 gtttcgatca cgatgtcttc caatggcata tcccgtgata cttcatatgc catcaacata
     3421 gcgatttcat cgactacttc acgaaaaacc tttgttccgc agtttttgtc ccgaataata
     3481 gttagtttgt gttgaatcaa tggatgatcg atcacttgaa atttgcccat tttttaagct
     3541 ctcctttgtt ctgtcgtttc tttttaattg taaaacaaaa tcaagtgatt gactagtcaa
     3601 actcgccatt tttcctaaga aaatccgttt ttgaaaagaa gttttcctgc ggacaagcaa
     3661 agcttattct tttttcttga tccaagaagt agataatgcc attgctgcac gcgttgcctt
     3721 tgtctgatcc atagcattta ccatgacaaa atcatggatg attccttgga agcgtacttg
     3781 tgtaacagga acccctgcat cacgaagttt gcgcgcataa gcctcacctt catctcttaa
     3841 tacatccgct tctcccgtta aaatcattgc tgaaggaaga tcatttagtt catttatatt
     3901 tgctctcaaa ggcgaagctg tgatttcagc acgctcttct tcattcgtcg tatattggtc
     3961 ccaaaaccac atcattcctt ctcttgtcaa aaaatagttt tctccgaatt catgatagga
     4021 atctgtatca aaatcagcgt ttgtgactgg ataatacagc aattgcttgg atattgggag
     4081 gccctttcgt tcttttgtta agatcgtcat gactgtagcc atgttaccac ctactgaatc
     4141 tcctgcaacg attagattct cgagatccag attttttgac ttggctaatt tattcagctg
     4201 ttgcaacaca gcataatttt gttcaattgc tgttggatat tttgcttctg gtgatcgact
     4261 atattctgga aagacaacga cggaattcgt acgaaccgca agttctctga tcaatttatc
     4321 atgggtttga gcactgccaa aaacccagcc tgctccatga atataaaaaa taactggtaa
     4381 tttatccata ttcccttctg gtcgtacgag acgaatattg agttttcccc attcgccagt
     4441 atccaccatc aagtcttcaa tatcgacgga atatttgttc acaggtgatt cttgtacttc
     4501 ttctagtaaa actcttcctt cttccggtgc tagttcatag atacgcggat gaggcgcatt
     4561 tgcatcactg aatgctactg cttccttttc taacgagata cgatcagtca tgacttttcc
     4621 tccctgagat ttagtgtgaa gactaaaatt acacctcata tactagagag catcaccgat
     4681 attgtcaaag aatccgtttt cccaaaaaat aaacagaaaa gcccaacatt gaacttttct
     4741 gtttactaat ggaatttaaa tttttatttt ttatgcaacg gaaatttttc agttaattcg
     4801 cgtacacctg ttttgacttc gtctagttga gcgttatcat cttttgcttg taatgctttg
     4861 acaactagtt cagccacttt tacagcatct tcttctttga acccgcgagt agtgattgct
     4921 ggcgtgccga ttcgaatacc gcttgttttg aatggactta gtgtttcaaa aggaatcgag
     4981 tttttattta cagtgatatt cacactgtcc aaaatgctct ctgcttcttt tccatttata
     5041 cctaactcgc gaacatcgat caacatcaga tgattatctg tcgcccctga aatgactctg
     5101 gttccaattg cttgattgaa aactttgacc attgcttttg cattggcgat gatttgttca
     5161 ctatattctt taaatgcagg atctaatgct tctttgaatg ctactgcttt acccgcaatc
     5221 acatgctcta gagggccgcc ttgaatacca ggaaataccg cactatttat tttttttgct
     5281 aatgcttcat cgtttgtcaa aatcatgccg cctcgagggc cacgcaatgt tttatgagtg
     5341 gtagtcgttg tgatatctgc ataaggaact ggattaggat gaagtcctgc tgctactaat
     5401 cctgcgatat gtgccatatc taccatcagt tttgcgccta cttcatctgc gatttctctg
     5461 aatttcgcaa agtcgatcgt tcgtccgtaa gcactggcac ctgctacgat caattttggt
     5521 tgatgttttc tagctaaaat acgtaccaca ttataatcaa taacttctgt tgtcggatca
     5581 acaccgtaag caacaaagtg ataggttttg ccactgaagt tgactggtga tccatgtgtt
     5641 agatgtccgc ctgcggaaag atccattcct aagatcgtgt cccctggttc taccaaagcg
     5701 agataagcag ccgtgttggc ttgagagccg gagtgaggct ggacgttcgc aaatttcgct
     5761 ccgaataatt cttttgcacg gtcaatcgct aaattttcaa cgatatcgac aaattcacac
     5821 ccaccataat agcgatgccc tggataacct tctgcgtatt tatttgtcaa gatacttcct
     5881 tgtgcagcca tcactgcttc ggagacaaag ttttcagagg caatcagctc caaattatgt
     5941 tcttgtcttt cttcttcttt ggcgatcgca gcccaaagat cagggtcaaa cgttttgtaa
     6001 tctaccacaa acaacagctc ctttttattt tcctacaatt ttatttttcc catcaaaaac
     6061 aaattgccaa atattcgtat ctcttctatt acgattagtt acgcttagtt tttcgttcac
     6121 tgatagaaga tttacttgat agcattgtat catactaaaa gaatgcgaca ataaccaatt
     6181 gatcattttt caaaataatt ttgtcctgct gcttttttca agcgattcat gtaagcattc
     6241 cccaatccag tttctggata cacttgtaca aaaatcaaat ctaatccaag tgttggttca
     6301 tctaatcctc ttagacctgc aaacaatcct ttagccgccg cttctactga gttgtcgtta
     6361 tacatataaa cagctgcagt atctgtccgc acttgatccg caatttcggg gcttgctatg
     6421 acacctgcac ggatcttctt attttttgcc cattgaactg cagttgacca atcgccatct
     6481 ctgaccatca gaacacgtgt atcgggtgag tagtgtttgt atttcatccc aggggctttt
     6541 ggtgtttcat tttcttttac aagatgctga tcaatagcaa caggagattc gatgactgct
     6601 tcgatttgtt ctttcgttac tgcacctggt cgtaaaatca taggcatggc tgttggatca
     6661 cttaaatcaa gaacagtgga ttctacacca attcgcgtag ctccatcatc aataatcccg
     6721 gtaatttttc cttgtagatc atgatataca tgatctgcag tcgttggact tggttttccc
     6781 gacgtatttg cacttggacc gacaagcgga acaccggaaa gttcgattac ttctagtgtt
     6841 tttttgttat ccggtatacg aaatgcagct gtggataatc ctcccgtcac aactgagggc
     6901 aaagtgtctt ttttgatctt aaatatcaaa gttaatggtc caggccagaa gttcttcaca
     6961 atcttctctg ctgccggatg aaagttgtcc acatactctt ttacttgttc aaaagaggcg
     7021 acatggacga ttaatggatt atcttgcggt ctccctttta cagaaaacac tttcttgaca
     7081 gcgtttggta aaagagcgtt ggcgcccaat ccgtatactg tttcggtagg aaaagcaaca
     7141 agttctcctt ctttcagtgc ttcggctgcc tcttgcaatt ctgtttcatc atatcgtttc
     7201 gtttccacag tttatccaca accccttttt catacattct tattttgtct gagtttatcc
     7261 tcaagttttc cactgtttgt ggataatcta tttgtcaata gtggataaac ttgttgataa
     7321 accaaaaagt cgtttacatc cttgtcaaat aagtgttttt ttataataaa aaaacaaata
     7381 aaaaattttt catccacaac ttcaaccata aacttggatc attcgttcat tgccaaaaag
     7441 atcctttttt atcgccactt ttttatctgg aaatgcttgc tgaaatattt tttttactgc
     7501 ttcaccttgg cgaaatccga tttctaaaaa aatctttcca tttgatttta gtacgcttgg
     7561 tgcttcaact gctatttttt cataaatagc taatccatcg ttctcagcaa aaagggccat
     7621 tttaggttcg aatgaccgga cactttcatc catcagttcc cattcattcc gactgatgta
     7681 cggcggatta gaaataatca catcaaattg ctgatccatt actggtccta atgtatctcc
     7741 atgataaaaa ctgattttcg ttccttcttt ctgagcattt tctttcgcta cttctaatgc
     7801 ttcttctgaa agatccacag cagatatatg ccaatttttt cttgctgctt tcaaactaat
     7861 agcaattgct ccagtccctg tcccaatatc tatcacttct aacggtacac caggcgtctc
     7921 gtctaaacac cattcgacta actcctctgt ttctggtcga gggatcagtg ttgcttcagt
     7981 tacctttaac cgatgatcat aaaaatctgc atatcctagc aaatactgag gtggatgatc
     8041 tgcaagcaga agtcgcagat cggtttcgat caaccgctgt tcttcttctg aaatctcttc
     8101 gttcatatga aggagccaat caagtttttt ccattgtttt cgttccaaaa ataaaaattg
     8161 gatactatat gcttctttcc catgatcctc taaaaaagaa gaagcccgtg acaggacttc
     8221 tcgataggtc attttaccca ttttgcatag cttccagttt tgatgtttga tcatacatga
     8281 tcaatgcatc aacgatctca tctaatttcc ctgctaaaat ctgatctaat ttttggatag
     8341 ttaatccgat acgatgatca gtcacacgat tttgcgggaa attatacgtc cggatccgtt
     8401 ctgaacgatc cccagttccg actgctgatt ttcgattggc atcatactcg ctttgtgctt
     8461 cttgctggat cttatcgtac acacgagcac gcaagatttt cattgctttt tcacggttct
     8521 tgatttgaga acgttcatct tgcatagcaa caacgatccc tgttggtaag tgagtcaaac
     8581 gtacagcaga tgctgtttta ttgacgtgct gtccgccagc acctgaagca tgatagatat
     8641 ctgtacggat atctttgtct tcaatatcga tctctacttc ttcagcttct ggcatcacga
     8701 caactgttgc ggtggaagta tggatacgcc cttgcgattc agttgaagga acacgctgga
     8761 cgcggtgcgc accactttca tattttaatt tcgaatatac gttgtctccg gtgatcatca
     8821 tgatcacttc tttatatcca ccgattccgg taacgttagc ttccatcact tctgttttcc
     8881 agccttgtgc ttcagcatac ttttggtaca tattgaaaag atcgccagcg aataatgctg
     8941 cttcgtctcc gcctgctgct ccacggattt ccatgatgat atttttatcg tcatttggat
     9001 cttttggtaa aagcaagatc ttgatttttt cttctaagac ttctttttct ttttttaatt
     9061 cagataattc ttcttttgct agttcagcca tttcatcatc cagtttttca ccaagcagtt
     9121 cttctgtatc ggtgattcct tgtactactt ctttataacg acgataaact tcgactgttt
     9181 cgcgcgtgtt tgcttcttct tttgaaagct gcataaaacg ctttgtatca gaaatcactt
     9241 ctgggtcact taaaagttct ccaagctctt cataacggtc ttcaattgct tgtaattgat
     9301 cgtacatgct tattctcctt ctgtaatcat tgatgggtga aagtaatgtt ttcgacaaac
     9361 ggggtaataa gcttcatttc cgccaatttg cacttgatcg ccttcataaa cagggtttcc
     9421 atcaatataa tgtaaattca tgattgcttt tttgtggcag aaccaacaga ttgttttcat
     9481 ttcttcgatt ttgtctgcat aaagcaataa atattttgat ccttcaaata actcgtttcg
     9541 aaaatcattt ttcaaaccaa atgccataac cggaatatcc aattcgtcca caattctcgt
     9601 aaaagcaatg acatgtttct tttttaagaa ttgcgcttca tcgatcagca cacaataggg
     9661 tttgctttcc attttctgaa ttacgtcaaa tacgtctgtt tcttcaaata tcggcatcgc
     9721 attacgtttc agtccgattc ggcttgaaac aacgcctaaa ccatctcttg tatcaatacc
     9781 gcttgtcatt aagacaactg gcttattttg ttcttcataa ttatgtgcga cttttaggat
     9841 ctcgatcgtc ttgccgctat tcattgcgcc atacttaaaa aatagttgtg ccatgctctt
     9901 tttcaccttc cagtttgttc ctatggtatt atacttgatt ttcagcattt tttacagtga
     9961 gaattttcat caagcacaga ttagtattaa atctattgct cacttttgtt ccaatttttt
    10021 gacaagaact aaacatgggt tccattcatc ccataaattt ggaaaaactt ccaaccttga
    10081 aaatcctaat gattcgtaga aacaaatagt ttgatcatat atagagtagt gcccctcgtc
    10141 tacagtcttc acttgcaaat atttgtaatg ttttgctgcg taaccttctg cttctttaaa
    10201 aagttttgtt cctaatcctt ggtgatgata gtcttttttt attcccatac aatagaatag
    10261 atttcggcag tatcttcact tgtctgtgaa agagtgataa agcctaaata ttcttctttt
    10321 cttttttcac accataaagg tagtttactt gattcctcga tatatttttc cgttgattca
    10381 ggaagcccaa accactcagg caagtctagt aatatttctc ggacacactt tcctttttcc
    10441 tctctatctt ttacaaacga tatcggcata ttctttctag attctccctt tttgaattga
    10501 gtatagcatg ctttctttct tttcacgtgc tataataagt taaaatttca aagttttacg
    10561 taaggagcta tttgatgaca aaaaatattt ttgattccat cgctaaccat tatgattccc
    10621 ctgaccgtca agcattagcc aagattattc gcgaagaact aactacttat ctaccgcgcg
    10681 acagccacca aaaagtcctg ctggattacg gaggcggaac tgggcttgtt agtttaccgc
    10741 ttgcggaaag attcaaagaa ctgatcattg ccgatgcttc agaaactatg ctgaaaatgg
    10801 cagaagaaaa gatccaagca gcagatctga aaaatgtccg aacgatccac gctgatgctt
    10861 ctgtcgaatt tcctgctgtc caagctaatc tcatccttct atcacttgta cttttacaca
    10921 ttcctgatac ggagaatatt cttacaaaac tttatgaaat tttagctcct ggcggtcaat
    10981 tgatcatcgt agactttgac aagaatgaac aaattagtca tccgaaagtc cataatggct
    11041 ttagccaaga agaattgaat aatcgattgg aaaaaacggg ctttgtctct gctactagtc
    11101 ataccttcca tcgtggggaa aagctattta tgaacaaaaa cgcttcgctt ttcttatcca
    11161 tcagccaaaa agcttaaaat gagattgcaa aaaaagtgag caactccaag aaataagaag
    11221 gaattttcgg aaaaagaagc tgtgacaaaa aacatgtcac agcttctttt tattttttca
    11281 tcacatgatt ttaatttctg aaagaggcca ataacggaaa acaacttttc cttggatcat
    11341 atctttgtcg actaacccaa acattcggct gtcttttgaa atcaagcggt tatcgcctag
    11401 aacaagatac tttccttttg gcacagtata ttcaaagtca ctcgtaaagg tggatgaact
    11461 ttctgcttgt gcttggaatc ctgagctata agcatattct ccttgtaact tatcttctga
    11521 aaattctttt ttgaactcat ccagataagg ttcatcatac tttttgccat taatggtcaa
    11581 ctggtcattt tccatcttga ctgtatctcc aggcataccg atgatccgtt taacaatcat
    11641 ccgttcttca tcccccggtt cctttgtagt aataatatcc attcgttcat agtttgagat
    11701 cttagatgaa atcaatcgtt gtccatcact taatgtaggg tccatcgaat gcccgtttac
    11761 agtaactggt gtaaacacgt acactctagc taataaaata gccgctaata caaggatcaa
    11821 aatcccccaa tttttcaaaa attctttcac agcttacctc ctacttgtat tttcctcgtt
    11881 atttattacg ttttttcaca atacttcgtt gtactttctt tattctacaa tgtttataaa
    11941 tgaaaggaaa gaataagtga tgtgttcgtc ttatctttct cgttatataa aaaaggaacg
    12001 tgacaaaaga cgtgtcacat cccccttatt ccgaataaac gtttttatcg caaccactga
    12061 tacacggcgt ttcatcacat tatgaatgtc ttcttctttg gctacgacta taaaccactg
    12121 gttcttcctg cgactgtgcc ttttttgcaa tcaatttcag acgataaggc tcatgatagc
    12181 gtaacccgtc tttgacaaaa tcaccgccga cgatgaacaa tccgacaggt tccaatgtgt
    12241 cttctgttga gtcaagtcga atggtcccta ctttttccat gtccgagtag cttcgtccaa
    12301 tatttagaac atactctttc tctcctgttt tcttgacata gtaataagga tacaatgtat
    12361 ttctatcgac cagaaatcca tccatgcgac cgagttcatt tgttttgatc tcaccatttc
    12421 caatcaaata ccgcatattc tcggctaatt tcaattgata atcttcgtca taagaaacca
    12481 tgacctcttg tgtattcact ttatcgatcg aatttccatt atctatcgat tcttctgtct
    12541 ggatgttgaa cgcttcatca ggtaaatact tcacaaaaag ctgagtgaca tcggctttcg
    12601 tgtttttatc taaaaagtaa taaaatacat ttaaaacagt aaaataaaca agcactagaa
    12661 atgcaagtcc atataagaaa aattgaagat agttttggtt ttgccaaagt ccataaacaa
    12721 ttctcaataa ataaagcgtg ggaatcacac ttaaaatcgt atatccacgg ttaagatatt
    12781 taggactgat gtctaaatag ccaaggaatt tatgcacccc gttgataagg tctagtaaaa
    12841 atgtcattga gaatcacctg cttgctggtt atacgtttgg gtatttcctg aatcttggtt
    12901 ttgctgtgct gtacgtgctg catcatcatt ttgcgtgtta tcatctacag tcgtactgct
    12961 tggtatcgtt tcggagctag cacttgtatc cggacttgta cttggattgg ttgaatccga
    13021 tggagtgcca tctggtaccg tattacttgt ttcgcttgag ctgtcagttg tatatgtctc
    13081 atcatacgac gaactagttg ttgtatcgtc ccatgtactt gtcgtagtgg tttcattcaa
    13141 actttccgtt gttgttggtt cagatgtcga gactgaagta gttggtgttg tttcttctac
    13201 agtactagaa cttgaacttg gtgcacggta gctggaacta ttcacaatac ctgtagtagt
    13261 cgcgacaatc gtcgagattg ttaatacagc gattggcttc aaaataggtg ctacttttcg
    13321 catcttatct cttccttcat tgaaatttat tcttgtttcc ttactttact acggacaaat
    13381 tatacagtct accttatttc taccataaat tctttatttt tttcttacgt ttttccgaaa
    13441 gatttcttta attttcctca aaaactacgg ttgatgtttt taagtaagct tttgcttccc
    13501 gattgatttc tttcagatcg catccttgct gcttggcagc gaacacgcaa ccacaataac
    13561 attggcgata aatatcatac tctttgcaca tttgcaaaga gcgttcatag cctttgtttt
    13621 tcttgaaatc acttggcaag tattgtgtcc cgtaaatctt ttggatatcc attccgatct
    13681 gattgatcaa agctgcattt ttctttggcg agatggtcag ggcacttcca aagtaatcgt
    13741 atcctagttc ttgcgctttt tgcgcaacaa gatctaatcg catattgaag catgcactgc
    13801 agcgagcacc accttctttt tcgttttcaa gatggtttgt taaaaccatt ttggtgaatt
    13861 catttggacg gtattcatca acgattagcg caacatgatg gtcagttttc tcattaaatt
    13921 ggtctacaaa tcgtttttgt tcatgtaatc ttcgcaaata ctcactttta ggatgaatat
    13981 tcgaatttga aaaaaataac gtgatctctg catattgaga catgaattcc aatgtgtgcg
    14041 tactgcaagg agcacagcat gtatgtatta atatcttagg ctttacttct tctttctccc
    14101 attgcatgat catttttttc agaactgtat cataatttat tttttgattt ttcatttttt
    14161 ctacgatttg ttgagcatta atcaatttgt tattcctcct ccttcttttt tctaggattt
    14221 tccttattat aagccatttc tattttaatc gaaagctgta ttgttatctg tttgataatt
    14281 tctttgagta ttcctaattc cccttgtata ctggtagaaa cgactattgt caggaggata
    14341 gtactgtgca tgttgattta ttctttcgaa ggctgcagcg gcgaggacag aagtttgctg
    14401 ccaatcattt ctcatcgatc caaatcatcg ttttttatta tatattgatg acggtcttat
    14461 cactcgttct attttatatg ccgatttttc gcgaaccaga tagccatgtt tcttttgtgg
    14521 acatgctgtt catggcaatc agtacagtga gtgtgactgg actatcgact tttgatatca
    14581 attctgtgtt caatgataac ggtattatac tgctggaaat attatttcaa gttggtggtt
    14641 tggggatcat gatgatttct actgcttttg tcattttttc taaacgacgg atcacactga
    14701 aacagcgaca gctgatcatg acggatatga atcaaccgcg tttgtctggt atcgtccgac
    14761 tgattcggat cacttttgct attttaatct ggtttcaatt actttttggg acattctttt
    14821 ctatttattt ttattacaga ggctattttg atcgttggcg tgatgccgtt ttttacggtt
    14881 tttatcaggc gatatcggct gtcacgaact ctgggtttga cgtcactggg gattccatca
    14941 agccctttgc acatgactat tttttcttga tcctgatcat gtttttgatt tttgtcggag
    15001 gaattggttt tcctgtattg atggagtgcc gggaatggct attatacaaa cgttccaatg
    15061 cgaagcttcc gtttcgtttt tccttgttta ccaaattagc tgtgttagct tttgttatct
    15121 tgtttgtttc gggaactgtc ttgatttatc tattggaaaa ggaccattta ttccaagatt
    15181 ccaatatgag tgtcaaatgg atcaattcga tgttttattc gattacgact cgtaatgctg
    15241 gtctgcagat tcacgatttg ggtgattttc aaatcacaac actgatcatt ttttctttac
    15301 tgatgtttat cggatgcagt cctagttctg taggcggcgg gattcgaaca actactgtag
    15361 caatcatcgg tttgtatcta tattccttcc tcaaaagtga agataacatc aatatttttg
    15421 gacggagaat cgatcaagat gatgtgcgaa aatcagtcgt tgtctttatg ctttctcttg
    15481 gtatgtgttt cttttgtatc gtttttttat ctgctacaga agaacaaacg ctgatctcga
    15541 tcatcatcga agtaacttct gcgtttggaa caactggttt atctttaggg attaccggag
    15601 acttgtctgt tgtgggcaaa atcacgattg ctacactgat gtttattggg cggatcggaa
    15661 tgctatatac attgatgtta ttcgtgccaa aagaaacacg agatctaggc tatgaatatc
    15721 caagcgagaa aattattatc ggttaaaatg ggaatatagg taagagggaa taataaaatc
    15781 acagcagctt gaaacaatca ttttgtttca agctgttttt ttgttaaatc atgcgatttt
    15841 gtccgatttc atgcactttc agccgtaacc ttttcttaag aataagaaaa gcaatttaac
    15901 ctttttttca acatatggta tgattagttg aatttattcg tcagcaaatc gtttttggag
    15961 gttacataat gggaatacgc agtcattttg cgattgcagt tggaaaaacg tcgcaatggg
    16021 cattaaaaac tttttttaaa ggcggatcaa gtttaccagg taaactagcg ctgaaagtcg
    16081 atccacatat actagatagt ttggcaaaag actaccaagt cgtcgttgtc accggaacaa
    16141 acggtaaaac attgactacc gctttaacag tcaatatttt gcgccagcaa ttcgatgaag
    16201 ttctaaccaa ccctactggt gcgaatatgg tacagggaat tgtatcgact ttcttgcagg
    16261 caaaaccaaa aaaaggacag aaaaagtttg ctgtcctaga aatagatgaa gcaagtttga
    16321 gcaaagtcac agaatatatg aaaccagaac tgttcttatt tacaaatatt ttccgtgatc
    16381 aaatggatcg gtatggagaa atctatacga cctataaaat gattgtagac ggtgccgcaa
    16441 agtcaccaaa tgcaacgatt atcagtaacg gtgattcacc aatcttcaat tctatcgaaa
    16501 cagtcaatcc tagaaaatat tatggctttg accatgaaga agatcgtgaa caaatggctc
    16561 attacaatac agacggtgtc ttatgtccaa attgtcatca catcttgcat tataaaatga
    16621 tcacttatgc aaacttaggg aaatattact gtccaaattg tgacttcaaa cgtcctgaat
    16681 tggattatcg attaactgat atggtacgga tggacaatgt gtcagcagat ttcgtgatcg
    16741 atggtcatga atacggaatc gaagttggcg gtatgtataa tgtctacaat gctttagcag
    16801 ctactgcagt ggcagagtac ttcaatgtcg atcctgataa aatcaaacaa ggtttaggat
    16861 atgacgagaa agtattcggc cgacaagaag tcatcaatat caatgggaaa aaatgtacat
    16921 tagtacttgt caaaaatcct gtaggtatca atcaagtaat cgatatgatt ggtctagctc
    16981 cttatccatt ttctttagtg gctttattaa atgccaatta cgcagacgga atcgatgtca
    17041 gctggatttg ggatggtaat tttgaaaact ttgccgatat ggatatccca gctgttattt
    17101 ctggaggaga ccgtcataca gatatgactt tacgtctaaa agttgccggg attccagaaa
    17161 ataaattgac agaaacaaaa gaattaccag aagtaatcga aaaaatcaaa gaattgccaa
    17221 ctgagcatgt ctatatttta gctacttaca ctgctgtatt gcagcttcgt aaagaactag
    17281 ctgctcaagg atttatcaaa ggaggaatga accgtggcta attatgaact caatatcgcc
    17341 cacctttatg gaaatttgat gaacacatat ggtgataacg gaaacctttt gatgttgaaa
    17401 tatatagcag aaaaaatggg ggtttcttgc catacggaga tcgttagtat acatgaacct
    17461 tttgatgctg ataaatatga cttggttttc tttggcggtg gtcaagactt tgagcaatta
    17521 atcatttcaa aagacatcca gaaaaagaaa gattctttga tcaactatat cgaaaatgat
    17581 ggcgtcatgt tagccatttg tggtggctac caattgctag gtcactacta catgggagct
    17641 aatggagaaa agatccaagg aatcagtgca ctggatcact acacgttaag tcaggaaaat
    17701 aaccggttta tcggtgatat cgttatccat aacgaagaat tcaatgaaac ttattatgga
    17761 tttgaaaacc acaatggtcg gactttctta ggtgaaggtg aacgaccttt ggggaaagtg
    17821 gtacaaggtc aaggaaataa tggtgaagac caatctgaag gtgtcattta ccgaaatgtc
    17881 ttcggttctt atttccatgg acctatcctt gcaagaaatg agaacctggc agctcgtttg
    17941 atccgcctag ctttagaaca acgttacggt aaagaattgg atctgcccta tcttgaagga
    18001 caaacagcct agttattcga aaaaggggaa tgtgacaaaa atttcgtcac attccccttt
    18061 ttcgtatcct attttaagcg acttgcttgg cataacggtt cacgttttgc ttgatattcc
    18121 cgattgtttt cggatcattg attcctgtga cttcttgaat caattgttcc aagttttcat
    18181 ggatcttcat ttcatgcaat tgacggcttt gttcatcttc aggatcatag taattaaaaa
    18241 taatccccat tgttgccgtc aaatgtgggc aagtcaagtt atgttcttgt agttctctca
    18301 ctggacgtgt aaatctttct tgataaccta acttacgtaa tggtgtccga gcgacacgtg
    18361 tgatcgcatc agagatattt ttgttttgga agcgatgaat gattttttca atatacgcat
    18421 gatgctgctc tgcatcaaac ccccatttgg caatcagcaa acttcctgtt tcctgcaaaa
    18481 ctgattttaa ttgtgccaca actaacgcat cttgcattgc ttcatcaatg gtctggtaac
    18541 ctaacaaggc acctgtataa gcgacagtcg catgaccagt attgacacta aatagtttgc
    18601 gttcgatata tggttctaga tcatctacat ataaaacccc ttttaattgg atttttttat
    18661 tttttctttg gctatcgtca atgacccatt ctttgaaagg ttccacttgg acgaataaag
    18721 gatcttcatg gtgttgtaat gggacgattc gatcgactgc tgcatttgga aagccgatat
    18781 atttgtcagt aaatgatgtt tccggaagat atttatacac ttctttttct agaaatgctg
    18841 aaccgccaat catattttca caggcaatga tatctaaaga tgttgtgctt ccttcctttt
    18901 ctctttcttg gatacctttt gcaatcaact cagcaataaa aggtaagata ttcgggccaa
    18961 tggcggtagt aactaaatct gcttcagcga tttcttggat tactttttct ggatttgttt
    19021 gattgttgat tcctttgaca ttttttacag tgattttttc ttttgattca tctgctaatt
    19081 cgatttcgta ttcttttctt tcatttaaag catcaatgat cgtgtgattc acatctacga
    19141 aagtaatctc aaatccatta gctgccaaaa cctctccaat aaatcctcga ccgatatttc
    19201 ctgcaccaaa atgtactgct ctcatttttc tctctcctta agcaattgct agattttccg
    19261 ttacttcttc tttgctgagc gcgtctgcta gctggacaac attgtccata tcactgcaat
    19321 aaagtgcgat ttgctgtaca agttgcaaat gctcatctcc gactcctgca ataccgaaca
    19381 aaacagtcgc aatcttttct tcttcttcgg taccaaaatc tacaccatct ggtacttgaa
    19441 cgacacagat gccggatttt ttcacatatt tttttgcttc atctgttcca tgaggaatcg
    19501 cgataaaatt ccccatataa acagataaca ttttgtctct atctaccatg gcatcgatat
    19561 attcctcatc aacgcaccct gcttctacaa gcatctgacc gcaatagcgg atcgcttctt
    19621 ctttggtttt aaaagatcga ttgagctcga tcatgtcgaa tggcaaactt tgcatgctgt
    19681 tttcctccct taagctgtct gtttcaaata ttgtgcaatc gattcgtatt tttgcggatt
    19741 gaccatgctg ttgactgata aatgaatgga ttgaggtgca gccatctgta ctttttccgc
    19801 taaactttct ttggctacga tcagtgaatc aggttcatct tttaaatctt ggatattgac
    19861 ttttcttaac gggatagtta aatggttctt gtctaatata tctttgagca cggtcatccc
    19921 cattgttgct gatccggaac gatcatcgtg gacaagtaga atctctttga tttgtttgat
    19981 gtttgctgaa agaaactctt ctgctggctc attctcaatt tcagaaactg atgttttctg
    20041 cttgctgctt aattcttgaa tgatttcatc atatcgaggt gaattcaaaa agttttctac
    20101 tgagacaaaa cgcgcgctcg gtgctttttg ttttgctctt tcttgtagtt cgacctgagt
    20161 aacgatcaat gtattcgagt catctgtcag ttggctgatt gcttgattgg tcaccgtttg
    20221 aggcaagtct gcttcctgta ctttttttct caagatcgaa gcgcccatcg cacttgatcc
    20281 cattcctgca tcacaagcaa aaatgatttt ttgtacgcca gagaatgtag ctccttgagg
    20341 aataccttgg gcacctttgg aagcttgctt agctgccttt gtctcttgaa cagatttttc
    20401 gaagtcttca tttgtatctt tcgcatccgc tttcaaaatt actgcagaaa taccaaacga
    20461 aacagctgcg gcaacaatca cgcccaaaat aacaggaagg taagaattga acggtgtcat
    20521 cgctagaatc gcaatgatcg accctggaga agctggcgct cttagtccag catccatcaa
    20581 ttggaaaatg aaacttcctg acattcctcc gcctataact gataagaata ataacggttt
    20641 catcataacg taaggaaaat agatttcatg gatcccgcct aaaaagtgaa tgatcatggc
    20701 tcctggtgct gaagattttg ctgctccttt gccaaacaaa gtaaaagcaa gtaatacgcc
    20761 aagtcctgga ccaggatttg cttcaagcaa gaatagaata gattttccag cctctgctac
    20821 ttgttcagtt cccaatggtg tcaaaatccc atgattgatt gcattattca aaaataagat
    20881 ttttgctggt tcaataaaaa tacttgtcaa tggaatcaaa tgggcagata aaatgatctc
    20941 tacacctttt gccattgctt gagtcaatgc atcgacaact ggaccaatcg cagaaaaacc
    21001 taataacgct aatccaaaac cgataagacc tgctgaaaaa ttattgacta gcatttcaaa
    21061 accggatttg atccgttttt ggaatagctg atcaaatttc ttgatggcat atccaccaag
    21121 aggtcccatg atcatcgcgc ctagcatcat tggaatatct gttccgacaa tcacacccat
    21181 cgttgcaatt gccccaacaa ctgatccgcg gtcaccagca attacttttc cgccagtata
    21241 accgatcaat aaaggaatca gataagttag cattgggctt accatggtag cgaaagcctc
    21301 atttggtaaa taaccatctg ggataaatag agccgttaat acaccccagg caatcagtgc
    21361 tccaatattt ggcatgacca tgcttgataa agtactgcct aatttttgta ccctcgcttt
    21421 tagcgaaatg ttgtttttgg gaatcgtccg ttccattttg tctctccctc tctccttttg
    21481 atactctaat tgtatccgct tactaaaaag agaaatagtc gtactttggc acgaaacttt
    21541 gtgccaaagg tttgagtatg tcaacaaaat aaaaagattt cggtatcaga aaacttcaat
    21601 tttaaataaa actgttattt taattttttt ataatatgca aacaataact tttgttagca
    21661 tttaatttag atgttttcca ttctattatg ttattaaatt ttatattgga ggcctatcta
    21721 tgacattact gatcaaaaac atgaacatga aacgtggtaa aaaacgtgtg attcgacaat
    21781 tgaatctttt agtagaatca ggagaagtag ctgctttgat tgccccgaac ggatttggca
    21841 aaacaacttt gctgaatggc attgcccaac tgctgccaac aacttatgat caattgtccc
    21901 ttcacaacat ctctcctact gcttatacag attatcgccg gtctttcttt tttctagaat
    21961 caacgaatca gttatccgac tatctatcgg ctgttgatta tttgactttg atcaaatact
    22021 attggcagag caaagtagaa tgccaaactg ttttccaacg attgaagatg actgagtacc
    22081 ttactttgcc gattggaaaa atgtctctag gaatgaaaca acatgtcttg cttgctgctt
    22141 acttgatcag tgattcatct gtcatgttat tcgatgaacc gttgaacgga ttagacccag
    22201 gaagtattga tatcttgaat agcctcatca gacaatggca gaaagagggg aagacgattc
    22261 ttctttcttc ccacgctatc gcgaatatcc aatcgatttg ttctaaagca tgttttctaa
    22321 aaaatggaga aatcgtcaca gaatcctcaa atatggaaga gattttagct atttatcgta
    22381 aattatatga ggtgtaacta tgtctttact tacatttgaa cgcaatctct tactaaaaaa
    22441 caaagtaaac tttttatttc ctctattgtt ggtcgtgctc tttgcattcc cacttttttt
    22501 tgatcataaa cttgcttata cagaattcga tgaactgaat cataactatg aagagatgca
    22561 acgtttgatt gaaacgttga aagaagatga gaatgagaaa gaatttgtgg aaagtttaga
    22621 gaaaagcaac aaactgatcg aagcaatctt acatgcaaaa aacacaggga atgtccagca
    22681 aatggtcgaa gcaacttatc attatgaaaa agatatactg gatcgactga tttctggtca
    22741 aagacaagga attccaatca ttgaacaaca aaaacgtgtc gagttgctcc gttatatgaa
    22801 agaacatcag atccaaagat attctatttt tgacttgcca gcgcatctct ctttagcaaa
    22861 ttactacgaa aatatttttt caggaatgat ttctagtttt ttgattttat gtataaccgc
    22921 cttgtttctt tcttccatca tctcttatga aaaaagaaag caggtaatct ctctagtcaa
    22981 tctattaccg gatagtatgg taaagaaaca tagcatccgt tttaccattt attatggtgc
    23041 agctatgcta agtctcgtga tgccattttt gatcgtctct atactagtaa taatcaaaaa
    23101 tggtttggga gacttccgtt atcctgtagg aacgatcatt ggtcaggaga tacgaatcct
    23161 gccgatgtat gagtatcttt tccagagctt tctgttcctg ttgttgtggg tgctcttttt
    23221 aagtacaatc agttttcttc tatctgcttt atttgaacat tctctagtca atcttttagg
    23281 tacacttctt tgtcttttct tagcagagta tcgcttgttt tcttcgattg gatggataga
    23341 atcaatcagt cattacttgc caacttctta tgttgatttt caaaatgtga tcataggagg
    23401 agatattttc tcgccactag cttcagaaca ggttactttc atgaatggta tcttgacact
    23461 tggtatatgg agtatcgttt tattattcat aggtatgggc actatctata taaaaaagag
    23521 ctattaaaac acaaaaataa taggggcggt gacaaaaacc ttgtcaccgt cccctatttc
    23581 aaataaacgg ttttctagaa taaatagttt tcaaaagctt gcatccgcag taataagaac
    23641 ctcccaacaa aaatagctcc tcttattttt atcttggttg aagttattac ttgatgcaag
    23701 gcagcttttt ttactgtgaa cattggttat atatgtccat gttcaaaaat catttggact
    23761 tcttcaatgg tttccgcatc actgagcgcc attacttggt cgatgtctga acagaaaaag
    23821 gctaaatctt ggagcaccgc taactgatgt tcttttttta aagccactac aaataagagt
    23881 gtcgcgattt ttggttcctc ttttgttcca aagtccacac catcaggcac ttggactaaa
    23941 tagattcctt cttctactac ttcttcatct ttgtcagtcc catgtggcaa ggctacgaaa
    24001 ttcccgatat agacactcgc tttttcttgt ctttcgatca ttgattggat atatgccggt
    24061 ttgattcccc cttgttgggt catccactgg ccgatctcgg tcaacgcttc tttccaattt
    24121 tgataggatt gatcgagcaa tattttttct gctggtagct gtatcatctt ttcaccttca
    24181 tttctttatt tcttcaatca ggattttcgc taacaactga taaacgattt ctttatttcc
    24241 tgagcggaag atctcggtgt tcaagtcatt catgatgatt gctccactga tctttcctaa
    24301 aagaatcccg tctttttctt ggattggcga aggcgccagc ataactaaca tacgggacaa
    24361 atcgactggc tgtctatcca tcccttcaat ggtcaacgga tgtttcaaat tgaaaataca
    24421 aaagatcggt ttagaaatca atgagctgga tgtatggaat aaccccatat ttgtatgagg
    24481 aataccgata ggtgcttgtt catatcgctt aagcagccgg cgatgaacca cctcttcatc
    24541 cgttactagt ccttcaggaa aataaggaaa taagctgcga atcgtttcgg aaatcgtctc
    24601 aggattatcc agttcttgga taaaaaaacg accgagtaat tgattgattt gatccatgaa
    24661 atgcattgtt tcctcataag tatcttctat catccactcg ttattgctgt tatacgtaat
    24721 tttttgcctt tttttcttct caatatgcga aaaagcttct tttagctgct tgacttcatc
    24781 ttctagcagt agcggggaga ctaaaatata ttttccaccg tatcctggta aaatagatgt
    24841 agaaataaca acatcatatt cttcttgtaa atcgattttt tttaaatcag caatccgata
    24901 gaaatgaatt tgttggatga agggaaaata ccttttcaat cgtagttcca acatgctagt
    24961 agaagctaat ccacttggcg aaaatcctgc aatactgata ttgctttctt tcggacttcg
    25021 ttccaatgaa ttcgcaaaat gaaggaccat ataagcgatc tcttcttcgg ataatttttt
    25081 ttcttgaaaa atccgctcta ctgctttacg gattgcattc gcaacttcct cgtattgaac
    25141 catgattttt tctaaaatcg gattggtcag tgtctcttct tgtaaaacgg ctcttgaaaa
    25201 cacaccagat aaatgagtca acagcatttt gtacaaagtt tcatcttcat aaaaatggac
    25261 attcgtctct tcacttactt cttgaatcag ttgttttact aaataagcaa gctgtgtatc
    25321 gaacgtctct tcaaagaaat tctgatcaaa tgagttcgtg aagtcattta ataatcctgc
    25381 aaaaaagacg atctcattta ctggataaag ttgttttgtc tcagaagcga tccgtgaaaa
    25441 caatcgttta gctgtctgta gtaattcttt gtttgccaga ctattatatg tctcatttgt
    25501 cagtaaatga tttttcgtca cacgctccat cgtcaatgtc agcatcaaaa ccaaatgttc
    25561 aagctttcta tcacttagat tggtcttttt ttggatcaat tcttccccga ttactttgcg
    25621 tgcaagagat agatgttgcg gatcaacgaa tcgaaaaaaa taattcagtg atgcatcgaa
    25681 agaaatacta tgaaaaagtt catattcatt gatttctaat tctaatacat tcgctgtcag
    25741 aagccggcgg tatttttccg gtccttcgat ctcgtatccc tggttccgaa tgatttccaa
    25801 aggcagttgg cgaatacttt cttccaactg tttgatatct gcataaaaag tggtattact
    25861 gatgcgatat gattccatga aatgagcaag actcaacggc tctgtcgtca gtaacaactc
    25921 ggctaaaatc gcgtgttgtc gtttagcagt ggataagtca ttacttttcc catctgtatt
    25981 ttcttttaat tgctctaata cttcttctga tgcctcaatg acaaatgagc ctctagctgc
    26041 ttttttcaaa gaagcattta ccgatttcaa tgagacttca agattatcta attcgcggta
    26101 aatagtccgt ttactgacct tcaataaatt catcattttt tggatagata caggtgacgg
    26161 gctactgaga aattctgcta ataattgttt ttctctgggc gataaataca tcttatattt
    26221 ctcccttcac gagtttttcg tattcattcg tagctaccca atgttcaact agaactagcc
    26281 gagggatctt ttcttctagc tgttcagtta cagctagttc tctttgtgcg atataaatcg
    26341 tttcttcttg gattttgatt ttttctattg attcttttga gataacaaac tgttttttcg
    26401 ctttttttgc taattgactt aaaatcgtca tgcccatagt ttgtgagccg cgtctgttgt
    26461 ttttatacaa aaatacaata ttagcaggcg acgttttttg ttctgtgata tctgctatct
    26521 cttttttttc ttcccgcttt ggaaattgga tcgcttcttt tattcgtgac agcaagatat
    26581 ctgtttccaa aaagtgatcc agtacataga tttgactttg aggtactttt tctcttgcaa
    26641 gacccgctag ttcatgttgc acgataacca gctgatttac ttggttattc aattcataga
    26701 tagagctgta tccgacagaa agatcgattt tttctgctgc taatttcttt ttcagcaggg
    26761 cggctcccat agcacttgat cccatacctg agtcgcaagc aaaaatgacg gaatgaatga
    26821 tagatggttc caagatttct cccctttctt tgaccgtttt gttctctttt tctttatttg
    26881 gtaatttcaa tagtatcgct gcacaaatga aggtcacaaa tgtactgatt gctatcccta
    26941 tacttacccc agctagttgt ggataaggcg cattggcaaa aatcacgagt agtgacccag
    27001 gcgatacagg tgcagctaat cccgtatcta accattgaaa tatcaacgtg ccgcttgccc
    27061 caccagccat tacagctaaa aatagatacg gtcgcagcaa gacaaatgga aaatagattt
    27121 cgtgaatccc gccaatcgca tggatcatca atgctccact cgcatttact ttttcctgtt
    27181 tttctgcaaa acaaaggata gaaagtaaga tccctaaacc aggtccagga tttgcctcca
    27241 tcaaaaataa ggaagagtac ccgactgttt gtgagaattc gattcctaaa ggtgtcaata
    27301 caccatgatt gattgcatta ttgaaaaata gtacttttag aggttctaag atcagactga
    27361 caagtggtaa cagattcatt gtgactagcc aagacacaac ggaggcgagc aacaagtgaa
    27421 cactatttaa aactggttca ataaaaacga ttccaattat acaaataacg ctaccagtca
    27481 gtcctactag taggttgctg acaagcattt catatccagc cttgaatttc acatggaatc
    27541 tagaaacaaa ttgttcatat acgatgccgg caagcggccc gataatcatc gctcctacga
    27601 tttgtggagc attggaacga gcgatcaacc ctaaagaagc aattgcaccg gcgactgccc
    27661 ctttttgtcc ccctaccgat ttcccgcctg aataactgat caagatgggt aaaagcagct
    27721 ggatcatcca atggcatacc tcttctaatg tggtgtgcaa atcgccagac acaccttttg
    27781 ttgctaatga caagattccc caagcgataa acagacttag atttggcatg atcatttcat
    27841 ttaagtgatg tccagctttt ctcagttgtt tcatagacac gcgactgctg ttgtttgctt
    27901 tccatttgta ttccatcttt ttcaccagac ttctatttat tgatggacgg attttatgta
    27961 gaaaaagcag caaacgaaaa accgtctgct gctttcagct atctgggaac tatttgcctg
    28021 gttcagacgc aatgattgct agttcacctt ggaccgccca ctcagaaacg ccatttggaa
    28081 taatacagct tgttcctttt tctaatggat atgtttttcc gtcaacgaca aggtctcctg
    28141 ctccttcgat taccgtcatc aatgtataag gggcttgttt tttgaaagat gtgattcctt
    28201 taatatccca ctcatataca ttgaaaaact cagtttctaa ataagtgacg atcgatgaat
    28261 tcccttttcg gacttctttg atttgtaatt ctggtgtttt cgcagggaca gttgttacat
    28321 cgatcgattg ttggatatgc agctctcttg tttgtccttg cgcatctttt ctgtcgtagt
    28381 catacacgcg gtaagtcgtg tcagaacttt gctgtgtttc taaaatcatg attcctttac
    28441 caatagcatg gatcgttccg cttggtacat aaaagaaatc acctttttta actggtactt
    28501 tcttcaaaag gtcatcccag cgcccatctt tgatcatctc agctagttct tctcttgtct
    28561 ttgcatgatg accatagatg atttctgcac caggttcagc atcgatgata taccagcatt
    28621 cagtttttcc taattcacct tcatgtttca tcccataggc atcatctgga tgtacttgta
    28681 cagatagatc atcttctgcg tctaagatct tgatcaataa tggaaacact ggttctgaag
    28741 gatggccaaa caattccttg tgttctgacc atagttcatc taatcttttc cctttgaatt
    28801 cgccattttc tactacactg acaccatgag gatgcgcact gatcgcccaa tcttctccga
    28861 ttttatcgtt agggatatca aaaccaaaga ctgaacgtaa acgacttcct ccccaaattt
    28921 tttcttgaaa aactggtttt aaaaacatag gttcctgcat aattcaaact cctctcattt
    28981 ttcatagcta ttatagcatt atttcggtaa taccgctttc tctttcaaaa agttttcaac
    29041 aatttcatct cgacatatga gatactccgc acgatgatcg acaggatgta cgcgatttga
    29101 caaaaatatc aacgcttctt gtgtttttat atcaatcaag aaaaacgtac ctgtataacc
    29161 agtatgaaaa agaatcgcat gaccgtcttc tacatccttt tttaagtccc atcctaaaga
    29221 acgatagcca ttttttttcg gtgtttgatc ttgcagtaaa gaatcaatcg tctcttcttc
    29281 taaaaaacga ccattacgga tttttccctt gttcaaatac atttggacaa aagtaatgct
    29341 gtctttcaaa tcaataaaga gacccgcgtt acctgcatgt tcagccaaaa ctcttgcttt
    29401 cggatcatga gtttgtccac gcaaaacctc acccgaaggc agttgttctg tgggaacgat
    29461 ttttttggaa ggaaaaggaa gaaataagct gttcatcatt cctaatggtt ccaatacttg
    29521 ttcttgaaag atttccactg cagtttcttg gtaaatttcc tctagcatca acccaagaag
    29581 aatcgtaccg gcatctgtat attttacttc ttttcctagt tgctcacctg gttctagctt
    29641 caaataagcg gcgatcaatt cttcctgaga tagcttatct ctgtttggta tccatgtttt
    29701 gatatcagaa gtatgtgtca gtaaatgacg caaagtgatt gtctgatttt caaattcagg
    29761 aagatattta tgaagcggtt gatcgagttc tatctttcca tcttctaata gacgtaaaac
    29821 taatgaagtg gttgcaacga ctttcgtcag tgaggctgca tcaaacaaca gatcttctgt
    29881 catcagctgc ttttcaggaa cgacttgggc aaagccggct gtaaatgttt ctacttgatt
    29941 ttcttttatg aaggcgactg ctacacctgg ataaaatcct tcttccatct ttttcaaaat
    30001 aagctgtttc gtgtgtggat acatcttttt ctcctgcttt tctatcagat tcttacagtc
    30061 caagcttaaa gcttaatcta tgaggaatca acctttttta cacaaaaaaa ctgcgcgaaa
    30121 aaccgcgcag tttcccccgg tatactattt tctctttcta tctctagaat aagcgatagt
    30181 atgaccgttc ataaaatgac gagacatgcg acaatcgtta agaaagaaaa agttaagcgt
    30241 cgcatcgaat gtcagtttta ttcttttctt ttggctcact gacgaaccac cattcgattc
    30301 ctatagcatc atagattgtg agtactgtgt gctttttgtc taagaagaaa tcaactgata
    30361 gttgctgcaa gtgagcaatc agtccttcca tgctttcagt atcgatcatg aatttcagaa
    30421 aatcaagtcc aatcacttca tctgtaggca aatcaattgc gcctccgcta gcttctgtca
    30481 aaccaacatg gaaatctcct tcattcaata catggatgcc ctcttcttca ttatgtacct
    30541 tcaaaccaag tacatgatta agaaattggc gttcttttgt taagttagta acatttaaat
    30601 ggattttttc aaaataagaa cctgttgata gtttactgaa tttttcttca gattttctta
    30661 ataatgcttc ttgatccatt gtttctggaa tttctctttg gtcgttctta ttctcttcat
    30721 ggtaaatttc caattcattc tcttctgggt ctacgagcaa aatccccata cgtccatgat
    30781 cttctaaagc ttctttgatt ggataattca ttttacggat acgacaaagg atatctgcca
    30841 tttcttctgt gctagggata atcaatgaaa aacggttcag ctttttgatc acccccatgt
    30901 gatcattcgc tctaggactt tcttccagca gcaacatttc acttccagct tcttctgttc
    30961 ctaaaatggc taattcgttt tcttctcttt tcaaatcaaa gccaacaacg ttcttgtaaa
    31021 aatcaatcat tttatctcgg tctttcaccc gaatggctac actttttaaa taggtggcag
    31081 cccccaattg aaaatctttc atatttcttg ctcccctcta cgtcaagctt tattttaacg
    31141 atggattctt cttctttcaa gcaataactt tgattttgtt aaaaaaaatg tgagaaaatt
    31201 cgcattttgc ttgttttttg taaattaatg agtaaaaact cttataaaaa gaggttgtga
    31261 aaaagctgtt ctgcatcaag taataagaac agccaaacaa aaatagctcc tcctattttt
    31321 cgtttggttg ggcttattac cgcagatgca agcttttgaa caccgtttaa ggaagaggtt
    31381 gtgaaaaagt cgcttagttt cgagtagtaa gaaaaatttt gtgaaaatgg ctttctacat
    31441 ttttgcataa atttggctta ataccgagaa actggctttt gaacaccgtt taccaagagg
    31501 ttgtgagcct gccgtttaac tccgagtcac aaggagcaat ttcaaaaaac agcttctcag
    31561 gtttgttgac tattgtgact tgtgaccgag gagttggcag gagaacaccg tttaaggaag
    31621 aggttgtaaa atcagcggtt tgacctgagt attagagata caaaacggaa aaatagcttc
    31681 tcatattttg ccgttttttg agctaatacc gaaggacagc tgattgaaca ccgtttattc
    31741 ggaaaaaggg actgtgacac gacttttgtc acagccccta aaaaaaataa taaatttgta
    31801 ctattctatg aagcttcttc ttcagaaaac tgactgttat aaagatctgc atagaatccg
    31861 tctttttcca tcaatgtatc gtggtttcct gtttctacga tcgaaccatg attcatcaca
    31921 ataatgttgt ctgcatcgcg tattgtagac aagcggtgag caacaacgaa acttgtccgg
    31981 ttttccaata ggcggttcat cgctttttga atcagtattt ctgttcgtgt atctacacta
    32041 gatgttgctt catcaaggat caggacatct ggatttgcta agaatgcccg cgcaattgtg
    32101 attagctgac gctgcccttg cgaaatattg cttgcatcct cgtttaatac agtgttatat
    32161 ccttctggca atttacgaac aaaatcgtct acgtgagcag ctttagcagc ctcaatgatt
    32221 tgttcgtctg ttgcatcgtc gttcccatat ttgatattgt catagatact tcctgtaaac
    32281 agccaagtat cttgcagtac cattgaaaac tgtgcgcgca attcatcacg tgaaagatca
    32341 cgggtatcta caccatcgta acgaatacta cctccagaaa catcgtagaa ccgttcaaga
    32401 aggttgatca gtgtcgtctt ccctgcacca gtcggaccta caatagcgac catctcacca
    32461 ggtttgacat ccaagttaaa atcagtcatt agcaagttat ctggtgtgta gccgaattga
    32521 acattttcaa aacgaacttt gtatggtgta tctttttctt ctggaaggcc agatttttca
    32581 ttggacatct cttcttcatc caacacttca aatacccgtt cggctgaagc aactgttgat
    32641 tggatagtgt tcatcaaact tgcaagttga gtgattggtt gagagaactg tgttgtatat
    32701 tgcaagaacg cttgaacatc ccctaatgtc atgttcccat ttgcaacttt tactccgcct
    32761 agtacagcga cgaacacata gcctagattt ttaacgaaat tcatcaacgg catgatgatt
    32821 gccgaaataa attgagcttt ccaaccagcg gcatacagat tctgattttc tttttcaaat
    32881 acttcctggt ctttttcagt atgattgaat gttttaacaa tggtatgacc accatatgtt
    32941 tcttctactt ggttattcaa taaacctaaa cttttttgct gatctgcgaa aaacacttgt
    33001 gatttcggcg ctacgatcat cacgatgatc aagcttaaag ggatcatcaa taacgcgact
    33061 aacgtcaatt gccagctgat tgaaagcatc atcacgatga ccccaatcaa tgtgactgca
    33121 ctagttacaa attgagtcaa attttgctgc agcgtgcttg cgatgttatc catatcattg
    33181 attgctcgag acatgatatc cccatttgta tgtgtatcat aataggaaat cggtacacga
    33241 ttcattttgg cttccaaatc atgacgtaat tcataaactg ttcgttggga aacacgtgtc
    33301 ataataaatt gctgtaaaaa gttgaataca gcagaaatca aatacatcac gattactgtc
    33361 gcaatgatct gcgcgatttt atcaaagtct atcggaaatt ttgttacttg ttggccttgt
    33421 tgcatctgtt gagcgccagc cattacacct ttgaatattt ctgtggttgc tttccccaag
    33481 acctttggtg tttggatttg gaagatcacg gctgctattg ctagtacaaa tacagcgatg
    33541 atcgcaacca tacgtttaga catatagcca aacaatcggc gtaccgttcc ccagaaattt
    33601 ttaggctttt caccttttac accgagattt ctgccaggtc caccatgtcc tggaccgcct
    33661 gctggtccat gagagggacg tgtgtttgtt ttactcatgc taagtcctcc tctcttagtt
    33721 gtgaatgaac gatttcttga taagtttcgt ttgttgctaa tagttcttca tgtgttcctt
    33781 tgccaaccag ttttccttca tctagcacaa ggatcatatc tgcatccatt actgtactta
    33841 ctcgttgagc aactaaaacg gtgatacttt ctttcatatt cgttttcaat gcttggcgaa
    33901 gattggcatc cgttttgaaa tccaacgctg agaaggaatc atcaaacaca tagatatctg
    33961 ctgttttgac taatgcccgt gcaattgcca gacgctgtct ttgtccacca gagaagtttc
    34021 ctcctccttg ttccacatgg ctatctaagc catcttccat ctctgaaaca aaatctttag
    34081 cttgtgcgat ttctaatgct ttccaaatca tttcatctgt tgcatccggc ttaccatact
    34141 gcatattgtc tcggatcgtt ccagagaaca gaactgcttt ttgaggaaca aagcccatta
    34201 attctcgcaa attatattga gtcatgtcac taatgtccgt tccatttatt tggatcgaac
    34261 cagattcgat gtcatataat cgagggatca aattgactaa ggtcgtttta cctgaaccag
    34321 tcccccctat gattgcgacg atctcgcccg acttggcttg gaaatcaata tcttccaatg
    34381 caagtttttc tgctccatga tatcgataat tgacatgatt gaaggccaat gttgcgtttt
    34441 ttccagcaaa agaaactgtt ttaggatttt cagggtcatg gataccgatt ttttcatcca
    34501 acacttcatt aatacggtca gctgaagctt gtgcacgagg caccatgata aaaatagcgg
    34561 aaagcatcat aaagctgatc aagatctgca tcgcataagt cataaatgca atcagattac
    34621 cgacttccaa agtcatatct gctatgtagt gtccaccaaa ccaagtgatt gctacgtttg
    34681 taccgctcat gatcaatgtc atcattggca tcatcaatgc gacgatcgta ttaactttga
    34741 ttgccgtatt tgtataatct ttattcgcta aatcaaaacg attttcttca aagcgtgtct
    34801 tatcgaatgc tcgaatcact ctgacccctg tcaatccttc tcgaaatacc aggtttaaac
    34861 ggtcagtttt cttttgcata cttttgaata atggaacagc aaagtacatg attccgccga
    34921 tcaaaataat cattactggg atgacaacta agaagatttt tgtcaactga tgatcttttt
    34981 gataagcaag tatgctcgcg ccaatcaacg tgattggtgc attgatcatc atacgtaaaa
    35041 acatttgtgt aaccatttgg atttgagtca catcattggt cgttcttgtg atcaaagagg
    35101 ccgttccata tttatcaaac gcatcttttg tcagactctc tgatttttta tagacatccg
    35161 tacgcaattg cttacccagt ttctgtgatt cacgagtagc aaaaaatgta tttgcgatag
    35221 cagctaagat actgatcaaa gaaaagccga tcatcacaaa acctgtatgc caaatataat
    35281 cgacatctcc ttgcgctacc cctttatcaa taatattgga ggtaagtgtc ggcaaatata
    35341 aatctgccag tacttggatc accatgaaaa ctgcagctgc aattgctgaa gtcaaggaga
    35401 tccgttttac gatttttagc atctagttcc cttctttcta tttatatact ccgtttttca
    35461 gccaagaaag tttcaaattg aattcactga ttgcttgctc tactgagtaa tcttcagatg
    35521 ttgaaaataa gcgatacgaa tgcgcaattg ttgtaaatac agtattcatc actaattgga
    35581 tcagtaattc caattcatga tcatttttta ctttcagctt cgtccgatcg atcaattcaa
    35641 gcaactcttt tgcatcttgt ttgtgttctt tatgtggatc gtgaggcgtt ttttggcgac
    35701 tcgtatgagg agcgactttt cttgaggcac ggtaatccat gttcataaac aagttacgat
    35761 aaaaagaagc attctcgcct tccaaaatct cataaatcat tttagaaaaa taggattcga
    35821 atcctttgaa tagatcacca tcggattctt tcattagttg taacatatct ttagagctgt
    35881 cacgtctcat tgtctcaaag taataaaaat aaagatcctc tttatcttca aaatactgat
    35941 agaaactgcc tctagggata tccgctaatt tgacgatatt agcaatcgaa gcttctttta
    36001 agggtactct agaaaactcg attctcgcag cctcgattag tcttttttgt ttttctttag
    36061 gcaaatggaa aaatgtctgt gtcggcatat ggattctcct ttctttcaag atgacacatt
    36121 gtcatatgac gctatgtcat tataacacct cctacctgtt ttgcaagaca tttgcatagt
    36181 ttttttcatt atcatccgat acattaaaaa agtgataaga ggaatccttc catttgaatt
    36241 aatgagagtt gcccattaaa atagccacat actaaacaaa ggatgagata aatggcccaa
    36301 tcaattagtg tccaagactt caataaattg cctctcgatg ctgacagcat cgttttagat
    36361 acaagaaata ccttagatta cacaaaaaac cacttaagcc actcgctttc tatccccgct
    36421 gctatcttgc caagacaatt aaaaaatcta gatccaaaga aactttatta tattctaagc
    36481 tatacaggca ggcgatcaga agcattagcc gatcaactta ctgctaatgg ttttcgtgct
    36541 gtttatatca ttggtgggat ggaagctctt cagtcgagtg ttgcttgaat attgcttgtt
    36601 agattcaaaa gaggctgtga caaaaaatcg tgtcacagcc tcttttatac cctgtctttt
    36661 tttagttatt tattcttcaa ccttatcaat atgacttgat agccttttct ttttcgagta
    36721 aactgatttt gttagtcata gttataacaa tcatagcaat aaaaggagaa ggtaagcata
    36781 tggcatctgt tttagtagtc aaaggtcatc ccctaactgc agaagaatcg cgcacagtta
    36841 aggcattgac gtctttttta acaagttata aagaaaatca tccagatgat gaagtgactg
    36901 ttttggaact ttatcgcgat gatattccgg aaatcgatga agaattatta tcaggttggg
    36961 aagcattacg tgctggtgca gaattcactt ccttatcaga aagtcaacaa caaaaaattg
    37021 ctcgtttcaa tgaattgact gatcagttcc ttgctgctga taaaatcgtt atcgcaaacg
    37081 ccttatggaa tctaaatatc ccaacaaaat taaaagcttg gttcgatacc gtcaatgtag
    37141 ctggaaaaac gttccgctat acagaaaacg ggccagaagg attagtgaca ggtaaaaaag
    37201 cactgcacat ccaatctaat ggcggtgtat acaacggaca agactttgcc tctcaatatg
    37261 taaaaggtat tttaaacttt gtaggcatcg atcaagtaga tcagctattc atcgaaggaa
    37321 tcgattatga ccctgaccgt gcagatgagt tgatgcaaaa tgcattagat aaagctgctg
    37381 ctttaggtaa atcattttaa aaattgagat aaatgcatac aaaagagaca gaggaaaaaa
    37441 tcttcaaagc agcatttgtg ccttggatat tttcccatct gtctcttttt gttattcttt
    37501 ctgctttttc aacggatttt cttcataaag agaagagatt gttgtgtacc attcaaaaac
    37561 atgagtaatc actactttag ctgctgcata aacaggaatc cccaagatca caccgatgat
    37621 tccgaacaat ttcccagaag tcagcagaac taataaaatc gttactggat ggattgctaa
    37681 ctgattccct agtactaatg gagagatcaa gcgtccttct attgtctgct ctactgcaaa
    37741 aacgatcagt actttgatga tcatgaatgg acctgctaca atggctaaaa agatagccgg
    37801 aatcatcgct aaaaatgatc ctaagtaagg gatcaggttt aaaaaacccg caataatccc
    37861 caacgtgaca gcatactcta aaccaatgac cgcaaaacca atcataaaca tgattgccac
    37921 agcaaaagcc acagttagtt gtcctcttat ataagaagaa acttgactat tcatttcact
    37981 cagcacattc aacgtcggtt tttgcatgcg tgtcggtaaa aatttgacaa aataaggtgc
    38041 taattgttta ccgtctttca atagataaaa taagataaac ggcatcgtca gcagagccac
    38101 taaaatagtc gctaccgcgc cgacaaaact tccaagactc tgaactgtac tcttagatat
    38161 atcttggatc atatcgcctg ccgaattcat gaacttatca cctgctgttt ccaactgttc
    38221 gcgaaattgg ttgaacagcg ggtcccgcaa aatctcggtt aatttattat caatcgtatc
    38281 tacatattga gggaagttac tgatgaagct cactgtttgt tcctgaatct tagggatgat
    38341 cactacgctc ccccatgcga ttagtgcaac aaccaaaaca aacagcccaa tgatactgta
    38401 aagccttggt acttttcgct tttcaaagta atcaactacc ggattcatca agtaatacaa
    38461 gattcctgct aaaatgatag gcagacctac gattgctaaa aattgccaga ttggtgcaaa
    38521 caaatatgaa acttttgtaa ataaaaagac gatcagcaat attaacaata caacaagtaa
    38581 ggctgtgact acttgattat ttaaaaacca gcgccaaaac cacgataccg gtctgttctt
    38641 cttatttttt ccttccataa ttcctcctgt tagttataaa aaatttggct tcccaaacca
    38701 atagcaggca gtctatgcgg atgaagatag attccatttg caatttgtcc ttcttctgga
    38761 caagcatcaa aaatcaatga tacgtgagct actgtcttta aattcccatt ggccatcgga
    38821 ccgacataat cgatcgtata tacctgatca tcaaaagcaa ttgttccgcc tgctttcaaa
    38881 gaaaaaggtt cgtcttttga tacttcttga atcaccgaat attttcgtaa ggcagctgtt
    38941 gctgttttat cgaacaaaat cagcatgggt tcttccttgt ttattgcttc tgtcccaatt
    39001 tctgtaatct ttgcctgaat cattgcactc tctcctttaa ttgctttcaa aaacagtata
    39061 acacattctc attctttagc cgtgtggaat aattatgtga tagaataaaa acgaaaacta
    39121 tttcattaca attaggagga atcagctcat atgatcgaaa agataatttt aggaacctat
    39181 acgcgtcgcg aaagtaaagg aatctatacg atcgaccttg atacagaaaa agaagaatta
    39241 gccaaccttt cattagctgt tgaagaaaat agccctacct atgtagcaaa aagtaaagct
    39301 ggcaatcttt acacagttac tagtgtggat ggattaggtg gtgccggtgc gtacgataag
    39361 gattttcatt ttttgaatgc ggtaacagag tctggcgctc ctttgtgtta tgtagcggtt
    39421 gatgaagcac gtcaattact atacggggcg aactatcata aaggtgaagt aaatgtctac
    39481 catatattag gagatggcga actgaaagca gcagattcaa tattccatca agaagcgaca
    39541 ggtcctcata aaaaccaaga tcatgcgcat gtccactata cggatctgac tcctgaccaa
    39601 cgattagtcg tatgtgatct tggtacagat cgtgtgtata cttatgatgt gtccgaaaac
    39661 ggcaaattga atcttgtaac taccttcact gcagagccag gaacaggccc tcgccatctt
    39721 gtctttcatc caaatggaca attcgcttat ttatttggtg aattagacag cacagtccgc
    39781 gtgctttctt ataataaaga aacaggtgct tttgaagaat tacagaaaat atcgaccttg
    39841 ccagaagaat tcgacggtga aaatggaggg gcagctatcc gcatttcaaa tgatggcaag
    39901 ttcctttatg cttctaaccg aggacataac tcgattgctg tattcgcagt ttttgaagat
    39961 ggttcccaca ttcaaaacaa gcaaatcatc tcaacagaag gggattttcc ccgcgatttc
    40021 gcactagatc caagcaataa ttttgtcgtg tgtgccaatc agaacaccga taatctgaca
    40081 ttatatcgcc gtcatcctga aacaggatta ctggaattac tgaaaaaaga tgtctatgta
    40141 ccagaatgtg tctgtgttta ttttgatcgt tagtaagaaa aggagaatga aatgaatcag
    40201 caagacgtat tagacagact acgggaagaa ctaaatattc ctttctttga tgggaaaatc
    40261 gaagataaag agtatagcga agaggaatat cagaaactca aagccgattt acagaactac
    40321 tttgaacaat atgtacagaa tgtagaaaac taatcagctt tccatactat ctgaaaagaa
    40381 catcaggaca agacttttcc gtctatcctg atgttctttt ctacaaataa aaaaccgccg
    40441 agatggttag actcgacgga aaaggagtat ttactcgatt ttgagtaagt acaaggttgt
    40501 tgttggttat aggtatgtca ttatcataaa ggattttgat cactctatca taaaggtaat
    40561 attacattta tattagataa ctctagtttt tattgttatc aaagatttct tttatttttt
    40621 caacaacaaa ttagtcattt tttggatggc agctgtcaat tggtctgtcg cttggtcttg
    40681 ttttgcttca gatgtattga atagatcttc atctacccct gattcaagat cgatactttg
    40741 gatcatttct tcacagcctg ctacatatga aagataagct ttttcaaaat ttttatgaat
    40801 gcccattgct tttgctggtg gacgcaaagt actgactttc ataagcattg cccgatattt
    40861 ttttgttcct tcttcaaata acaggatgat ctcttcaaga gtcgatttgt ccagttcact
    40921 tgtttttcct tcatcaattg cgtttctgat cacttcatat ttcggatgca ttccttctcc
    40981 gattgcttct gtttccttga cgatttgatc gatggactgc acataatagc caatattcgg
    41041 taacatgttc gttttcctac tttctccatt gttgttatta tttattctac ttgtttttat
    41101 cctcaaatga caagtacttg aaaaaattta atggtttcta tacagctcgc cattcttatt
    41161 cgtgctcaaa gaaaccatct gctaaactat attgtttccc tgcgacaatg tcatattgga
    41221 tcaattgata ttcgtcgtaa atctcttgtt gcgagcgatt gaattgcgct tctttatacc
    41281 actgtccgtt ttgatagtac agttctcgtt caaacgccgg aagttcctgt tctaatgata
    41341 aaagcagctg ataaaagcca tttgttgtct gattcgtctg ttccattaga ttcgctgcaa
    41401 aataaaacgg actggtgatt gcatcgtgag tcgtttgctt ttctaattct cctttactgt
    41461 cgaacataag aaattgtgtt tcatgcaatg tttgtttgtc attttttgct tggatcgtat
    41521 ctgaatagat ccctggaaga tgatcccccc aaaaaacaac taaagtcctt ctagaaagat
    41581 tcttcaattc ttccgtgaac tgcttcagtg ccgtgctgct ataggaaata tcttgcagat
    41641 aattctctaa gtcaagtgtc ccacttccat ctgaagtttt tgcaggatag tctagattat
    41701 catactttcc atcgtagggc atatgtgtct gcatcgtgac taaatgaatg aactgaggtg
    41761 ttttttcttc cttgagaagt gtcattactt ctttgtaagc tgactcatca gaaatatatg
    41821 gattattctc tatcgtatcc gtataggtca tcgtacgctc gctgatgaac tggtcaaatc
    41881 ctaatgtctg ataaacatcc tctcttttat acatcgaagt attgtatgga tggatcgctg
    41941 tcgtctggta tgattgtgcg tttaacgctg aaacgataga aggaagctga tccatttttg
    42001 gtacaagcat cgtgtaaggg gtggtgagtt gcgcattaaa taacgccata gaaaaaccag
    42061 tcaatgcttc aaattcgata tttgctgttc caccgccata gttttgagaa agcatattgc
    42121 cactatatgt ttgatcagct acttcataat aatctgccaa tggctcacca gatacttcta
    42181 cgccgtttaa tcgactagga tctgagaaac tttcactcat cacgaacacg atgttcggcg
    42241 actcttcctc tacagtttta tttttttcat cggctagctt ctggtatttt tcagtgattt
    42301 ctttgatctt ttctttcgaa tatccttcag gttcatccat tggttctacc ttcagattgt
    42361 acaaaaaccc accgataaaa ccagtgttat agtagttcat tttctggctg taaggtatcc
    42421 atagtgccgt tttattatat gcttttcgca acaaattatc gggattgttg aaattactga
    42481 tataccctag cagtccaatt gccacaagca gtgtcgttaa tcggatcaat tggaatcgcc
    42541 ttcctttttt caggcttcga aacatgtacc agcaaaacaa tcctatcacg gttcctgcgg
    42601 cagctaagat cactgtaaac agcatagtgc cggtcatatc tttcagcaat ccgatttcag
    42661 tgatcatctt caaatcgtct ggataaatcg gttcttgccg ataactcatt ttcatataat
    42721 ttgcaaaacc taatacaccg atggctacga catacgtaag ggaacctaaa gggacagatc
    42781 ctgctagtgc aatcagaaaa ataagaataa tcagcaagac gagacaggct aagaagaatt
    42841 tttccgtatg ccaagaaaaa gcaaatttca acgcaaggtc tacggataga tcattttgac
    42901 accactgcaa aaataaatta ctaaaaacaa caagaaaaaa gatactgatg attgctgctg
    42961 ttccttttaa aatctttttc tgtttggtcg aaagtctgct tatatatctt ttcaaatgct
    43021 tgctccttca tttctatcaa taaaagaatg ttgcttctct tattttagtt gtacgaaatt
    43081 cgaaagtaaa gaacggaaag aagaattaat gaaatccaaa tattctcttt ctttatggcc
    43141 tttctggttt ctttaataag cggacctttc gtactccaga aattttttct agctgttgtt
    43201 tcacttgatt gagctgttca aaatcagtac tgtctatgtc aatcaatatg tagacatgct
    43261 cattcttatg gttacgcgat atatctgcga tcgctagctc gttctcattc agcagagaaa
    43321 atatctctgc taatatattg gttttctttt gataaaatat agtgaatcga aacggcgctt
    43381 ggaaaaacat tcgtgcggat ggataattga ccgcttctct aaccgtaccg aacaaaagat
    43441 aatcttttaa ggcttcaact gccaaacgtc cgctgtctgc caaagcttcc tgagtcgatc
    43501 cccctagatg aggcaacata agtatacggt cattttctaa gaactcttct tctggaaaat
    43561 cagtcaagta tttagccaga tgttgttttt ccaatgcttg cataacagca tatttatcaa
    43621 caatttcact tcttcctaca ttgataagta cagcatcttt tttcattttt tctatattcg
    43681 cctgatcgat caatcctttt gtatcttctg tcaacggcag catgactacg atgtaatccg
    43741 aggtagaaag aactgtttct aaatctgctt gccgaacata atccaactgg gcatcgcgga
    43801 tagaataacc caagacatcc atccctaagc tatagcaact tagcgctact tttgtgccta
    43861 tcgctccaag accaagaaga ccgatggttt tgccttgcaa ttctcgtccc acataagcac
    43921 ttcttttgtt ttctgcctgt tctaaaatat taggacctgt tagtgtttgt accatacgac
    43981 ttgcttcgat tatcggacgg gaagataaga gcaaacagca caaaacaagc tcttttactg
    44041 cattagcatt tacacctggt gtattcatga cgatcgtccc gttttcagaa gctttttcaa
    44101 cgttgatcgt gttcacccca acaccagctc ttgaaattgc tagcaaatct ggtgtaagcc
    44161 attcatcttt cactttcgta ctacgaataa ctattccttc ggctggcaaa tcatctatta
    44221 ttttgaaata ttccccttgt aacttttcta tctcttgttc tggaatagca tcaatcaaat
    44281 gaacgtgata cataaaaccc cctccttact aacaagtatc tcgaaatttc tgcaattaga
    44341 caactgttta ccatttgact tcctagaagc aaaaagagca gttagagcag agtaggctga
    44401 gtgataaaaa taaggctatg acaagttact gccataagcc ttattttcga gagcaaaata
    44461 ttgagggtga gatatcttga taaatggtgt tccgttagct gacattgata ataagactaa
    44521 atttcaaaaa agttgaaaag caaatttcgt caatctcttc ttatttctta aaactaagtg
    44581 gctttttcac aacctctttt tatctaataa ccactgtttc caactcaact aattttgccc
    44641 acgtttcaat ttgatctgtt gttagattta gcgagacaac ggtatgatga ccgccacctg
    44701 cctgaatcca tgaatggaca ccttcatgga aattcggttt agttttccat aacacacgtg
    44761 caacaggtaa attaggtgct tcagtcgttg gttcaaaggc ttctacttca ttgatcagca
    44821 gtttataatg cgtaccgaaa tctgccatcg atacgactac cccttctcct gctttcccat
    44881 caaatacaag acgcgccgga tcttctctat ctcccattga taaaggagaa acaacgattc
    44941 ttggtttcgt cgcagcaagc gtcggatcta cttccatcat atgggattcc aagattgctt
    45001 cttggccact agctagctcg taagtataat cttccatgaa tcctgtatct ttccctcgag
    45061 ccatgatttt cagcaaccga tcaatcgctg cagttttcca gtcgccttcc ccagcaaaac
    45121 cgtatccttc tgccatcaaa cgttgtacag ctagtccagg tagttgtttc attccataca
    45181 ggtcttcaaa attagtcgta aaagcgttat agcctccttc ttctaagaaa cggcgaatac
    45241 cgatttcctg ctgagcttgt acttttacat gttcctccca tgtcttttct tcataatcac
    45301 catagtcgaa ggtatacaat tccttgtact cttcaaataa ttgatcgact tcttcgtctg
    45361 atacgcgatc gattacttgt acaagatctc cgataccaaa ataatcaaca gtccaaccaa
    45421 attgaatctg tgcttccact ttgtctcctt ctgtgacacc cacgtttctc atgttgtcac
    45481 caaaacgagc cacttttatt ccaaaacttt cattataggc tactgcaaca tccatccaat
    45541 cagcaatctc tttttggatc tcaggtcgtt tccagtagcc aacgacgatt ttattttgtt
    45601 tatttaatcg agcattgatg aacccatatt cgcggtcacc atgagcggat tgatttaaat
    45661 tcatgaaatc catatcgatc gttttccaag gaatgctttc gttatattgc gtagctaaat
    45721 gaagcaatgg tttttgtaga agctttgtcc cgcggatcca catttttgct ggtgagaaag
    45781 tatgcatcca agtgatcaca cctgctactt cttctcgata attgacctct ttcatgattt
    45841 ttgtgatcgt atcagcagta actgctaatt cttgaaggcg gattggataa ggcaattggc
    45901 cattttcatt cagttcatcg accatttctt gtgcatgttt ctttacttct cgcagtgctt
    45961 cttccccata taaatgctgt gatcctacaa caaaccaaaa ttctttttct ccaatattca
    46021 acataattag ccactccttt tatttgtttt gtccgtaata cgcatttttt ccgtgttttc
    46081 gtaaataatg tttatctaaa atccgttgag gcagctcttc tgaaaatgaa ttgagctgtc
    46141 tggtaaataa attcatcttg catacttcat ctagtacgac tgcgttcatt accgcacttt
    46201 gcgcatcttt cccccaagta aatggaccgt gtccgtgtaa aagtacccct ggaattgcta
    46261 agggatcaat tttgcgttct ttgaatgttt ctatgataac ttttcctgtt tcatattcgt
    46321 acccgctgtc gatttcctgt tgtgtcaaaa atcgagcaca aggtaccgat ccataaaaag
    46381 tatctgcatg cgtcgtcccc atcgcaggaa catccaatcc tgcttgtgcc cagatcgtcg
    46441 cccatgtcga gtgagtatgg acgattcctc cgatttgagg aaatgaacga tataaaacag
    46501 catgagtagg cgtatccgaa gagggattga gtttaccttc aatgatatga ttgtccaagt
    46561 ccacaacgac catgtcgtct gctgtcatct cttcataact gactccgcta ggtttgataa
    46621 cgaaatatcg tgtttcagga tcaaaagcgc tcacatttcc ccatgtatat ttgacgagtc
    46681 cgtgtttagg caagtcaaga tttgcttggt atacttcttc tttcagttgt tccagcattt
    46741 tctatcactc ctttttcttg caattgatga atcgctgttt tttcaatgtc gatcccctca
    46801 cggtaacgtc tcataaatat ctgatagcct gctatttctt ctgctgaagg tgtgatggtg
    46861 attccttggt cttgtccaaa cacgtcttct gccaagaagt tttctaaaga cttcccatgt
    46921 cgatccatca tataggctgc taataacgcg attccccacg ctccaccttc tccggctgtg
    46981 tccatcactg taactggtgc ctccatagca gatgctagaa tccgctgtcc aacttctggt
    47041 gttttaaaaa tccccccatg ccccactaaa cgatcaattt ggacattctc agatttcaat
    47101 atatccattc cgattctcat tgcaccaaaa gcactggcta aatggatccg catgaaattc
    47161 gctaaatcaa aacggctacc tggtgtacgt acaaataatg gccttccttc atttactcct
    47221 gtaatgtttt caccggaaaa ataaccataa gaaagtaatc ccccgcaatc cgtatcgcct
    47281 tctagcgctt tgttgaataa taccgtgaat aatttatctc tgcttatctc catacccaaa
    47341 gaattggtaa attcttcaaa aatactgacc caagcattga tatccgaaga gcagttattc
    47401 gtatgaacca tgcctactag ttctcctgaa ggtgtagtga ccatgtcgat ttccggatgg
    47461 acattttcta gttctttttc taatacgatc atagcgaagg cggaagtacc agccgaaatg
    47521 ttccctgtcc ctttggctac actgttcgta gcgaccatac cggttcctgc atccccttct
    47581 ggcggacaaa ccgggattcc tggtctcaaa tttcccgtag ggtcgatcag ataagcccct
    47641 gattcgctta acttgccagc ttcttctcct gctactagaa ctttaggcaa aatgtgatcc
    47701 aagtcaatcg ctacgtgcgc tttttcgatt aactgaccaa aaatattttt catttcttga
    47761 tggtaggttt tcgttgaagg atcgatagga aacatgcctg atgcatctcc tacgcctagt
    47821 actttctcac cagtaagctg ccaatggaca taacctgcaa gcgttgtcaa aaaattaatt
    47881 tctttcacat gttcttcttt attcaaaata gattgataca aatgagcgat actccatctc
    47941 tgcggaatat tgtattgaaa tttttccgtt aatattcgtt ctgcttcttc agtgattgta
    48001 tttcgccaag tacgaaatgg tactagtaac tgttccttgc tatcaaatgc tagataaccg
    48061 tgcatcattg cactgaaccc aatcgacccg attgtcgtaa gattctcgcc atagatttcg
    48121 aatacttctg ctgccatttt tcggtaactg acgcgcagtc ctttccaaat atcttctaat
    48181 gaataggtcc agataccatt ttctagtttg ttttcccact cataactacc agcggcaata
    48241 ggagtaaaag atgaatcaat caatacagct ttgatcctag ttgatccaaa ctcaatccct
    48301 aaagatgtac gaccatctat gacatctaac atactttgcg catttacttc cttcataatg
    48361 atttaactcc ctccttctcg tcaaacctga tcaaaccgtc tttttagtag cgcttacaat
    48421 gattattgta tacttttgta cgtacatgtc aagcagttat ttacaagaat acaataaaaa
    48481 acacttgttt tgtacgtaca taagttataa aatgaaattg cttacaaaat ctgatcaacc
    48541 gccttctcga aattctagaa ggagagaata cttatgaaaa aagaaaaaaa agtttcctca
    48601 tcgtttattt atttttttgg cgcatttggc ggcattctat ttggatatga tattggtgtt
    48661 atgaccggcg ccttaccttt tttacagcat gattggggtt tggcaggtaa agcttctttg
    48721 ataggatgga tcacgtcttc ggtcatgtta ggtgcgatcc ttggcggctc tttatctggt
    48781 cttctttctg ataagcttgg acgacgaaaa atgattcttc tttctgcact tatttttatg
    48841 gctggttctg tcctttctgc atctgcccct cacaatggtt cttattttct gattgcagca
    48901 aggattcttc taggtttagc tgttggcgct gcatctgccc tagttcctgc ttatatgtct
    48961 gaaatggctc ctgctagact aaggggaaga ttgtcaggga tcaatcaagt gatgattgct
    49021 tctggcatgc tcctttccta tgttgcagat tatttgctaa aagggttgcc tgaaacgatg
    49081 gcttggcgcg tgatgttagg gctcgctgct gtccccgcgc tgattttatt tttcggtgtt
    49141 ttagctctac cagagtcacc gcgttttctt atgcaatctg gccgcttgga agaggcaaaa
    49201 agagtattga actatattcg gacaccaaaa gaagctgaac aggaattcga acaaatccag
    49261 ctgaatgtca aacaagaaaa gacaaccgga acttcttggc atactttgtt tttagaaaaa
    49321 tatcgttcct tagtcattgc cggtattggt gtagcagtat tccagcaatt tcaaggagct
    49381 aatgctattt tttactatat tccgctgatc gtagaaaaag cgactgggca tgcagcgagc
    49441 gatgcattga tgtggccgat catccaagga atcattttag ttgctggttc tttgctcttt
    49501 ttggttattg cagacaagtt caatcggcga actttattga aaataggcgg tagcgtgatg
    49561 ggactttctt tcatcctacc agctgtttta ggaactgtac tggatgctca tacaaattcg
    49621 ttgttgattc tcttgttttt atgtatttat gtcgcatttt attcttgcac atgggctcca
    49681 ctgacatggg taatcgtagg cgaaatattc ccactagctg tccgcgggcg agcatctggc
    49741 ctagcctctt cttttaattg gattggttct ttcctagttg gcttgctttt tcctgtgatg
    49801 actgcttcta tgtctcaaga aatcgttttc ggcatttttg ggatcatctg ctttttaggg
    49861 gttttattta ttcaagagat cgtaccagaa actcgtggga aatctttaga ggaaatcgaa
    49921 caaagtgcat ctaaaaaaac ttatcctaaa cgtatttcta tccatcattc ttaaagaggt
    49981 tgtgacagaa gtggtcagct tcaagaaata agaaggaacc gcttagtttc cagtcacaag
    50041 gaacaatttc aaaaaacagc ttctcatgtt tgatgaatat tgtgacttgt gaccagttgg
    50101 taggagaaca ccgtttagtg gagaggtggt gaaagaaacg ttcagccttg agcgatgaca
    50161 aaagctctca caaacattgc gacgagtaac cgtaggagca ataagaggcg gtaaaaaccc
    50221 gtctcttatt tttcgttttc tttcactgtt tcccgttcaa ctagtacagg ttcatagaga
    50281 atatttggct gtgcctgtcc tttttcaatc gttgtgacga tccaccgtgc ggcatcttgt
    50341 cccaactttt cttttggatg cgtcaatgtt gtcaattttt tattccctaa atggcttaaa
    50401 gaagaatcgt ctgttcctac gatcgatagg tcatctggaa tatgatagcc attttctgtc
    50461 aacttatcta gcattaaact agctatttga tcgttatagc aaatgatgcc atctaaagct
    50521 tgttcttctt tcaaccgttg tactgttttt tcagcgattg tttctcgtgt ttccgtggtg
    50581 aaagtaatga tatcttccgt caaaaaacgc acattatact gttcacacgc gctgataaaa
    50641 cctttcatcc tgtattttcc ttgaagatcg tcgatttttg tgatgaacaa cagacgctga
    50701 tgtccttttt ttatcaaata ttctgctgcc ataaaaccga ctttcacatc atctaaacaa
    50761 atataagagg catttaactc ttcataagca gcattgatca tcaccatcgg aatgccttgt
    50821 tctctcaaag caacataaag tgctaagttt gggttatact gattactttt cgtaggctca
    50881 acgatcaaac catctacccc ataagcaatc attttcttca aacactcttt ctccaattcg
    50941 tgatcgttat tcgtactggc taaaagcaat gaatacccag attctcgtaa ttcattttcg
    51001 attcctcgga taatcgacgg aaaaatataa tcagagagat atgtggtgat gacaccgatc
    51061 gtttttgttc tgttcaatgg tgttttttct ttcttatagc tgtcatctac atatgtgccc
    51121 gacccttttt ctttacgcag atagccctca tttaccaaca cagcgattgc ttgccgaatc
    51181 gtatgtctgc tgacgtcata tatttcttgc agcttgaatt ctgagggaat ggttgtattt
    51241 acttcgtatt cctcacgaag gatcttttgt tttatctctt ctgcaatatc ttgatatttt
    51301 gccatttgcc ttgccccttt ttatttgtac gtacatatat cataacgagt ctgcaaggtt
    51361 tattcaagca aaaatcaagg tttcttgtgc tcataaggca tacggaacag gttcaccaaa
    51421 ttctggaaat ccttgctcat tccacgtaaa gcattgcgcg ttcgcgtgcc gattaggatt
    51481 gtctaacgga tccccttttt ggttcttctc tggtcgagca tgatagatca aaatatcaaa
    51541 gcacccgtct tctgaaaccg taaacgagtt gtgaccagga ccaaattgct tatttttttc
    51601 agaagaaacg aatactggct ccgataattt atgccatgat tcttttaata aaagattctt
    51661 gtgctcatca gcccacagca ggcccatggc atagttttca tctgttgcac taccagaata
    51721 cgtaatgaat attttcccat tgcgagtaag gactgctgga ccttcattta ctgaaaaacc
    51781 ccgtttttcc cattcatact caggtataga aaggaggatc tgcttcccct ttaacgtcca
    51841 aggattatcc atttcggata gataaagatt agaattccca gtaatttcag gatcttgttg
    51901 ggcccacaca taatatagct ttccttgaga agagaaagtt gttccgtcta aactgaaagt
    51961 ttcccttttc gtttttattt gtcccttttc tatccaatct gtattcattg gatctatatg
    52021 ctgattttca agtacgaaca tgcggtgatg atgagattca tcacgtatag ttttatgatt
    52081 gcttgcagca aagtaaatat accattttcc attgatataa tggacttcag gtgcccagat
    52141 caattcactc atcggtcctt cttcatgagc ctgccataca atcaggcttg cagcatgttc
    52201 taattcattc agtgactttg cccttcttaa ttcaatcact tggtagcctg gaaccgatcc
    52261 tgtaaaataa taataaccat ctgtatgttt atatacccaa ggatctgccc gttgccgaac
    52321 gataggatta ttataaagtg tcttcatcat aacaaatttc ctcacatttt ctttattcta
    52381 attacattcc aagagtattt ttctatccct acatttaatt cgtcatgttt ttctattgaa
    52441 aaatagttta tttcaggttt tattttttct ggttcttcac gtgtattttt gtccaacaga
    52501 tcgctactgg ttaatgtgta gtgctctcct tgatctagca aattgaaatc atgttcaatc
    52561 gttatctttt gttgttcatt tgtgcgattg atcaagaaaa tagtcagctg attgccgtta
    52621 tctacgatca cactgtccac ataaggaaca ttttttatct tttcacaatc ataaacaggg
    52681 caaatgattt gttgtttcaa tacttgacct ttagcatatt tcgataagtg ttgcatcaca
    52741 taataagttg gattcctcca tgcttgtcct ttagcatctg tcagtattaa aggtattgtg
    52801 tttactaaca atgattgaca actaatcttt acgcgatctg cgtgtcgtaa aatagccagc
    52861 cctaatgaac caaataataa tgtatcttcc atagtaaagt aacaccaatc gatgggacta
    52921 ccgacttcaa aatccctatg tcttttttcc ggttgggcat gtacattcca ttcatcaaac
    52981 gctagataca ttgttttctc acttctcaaa tatcctttta cataatcaca agtagcaacg
    53041 atttcttcaa tttgacgatc gaatcgataa gcttttgcaa ggtatgtcgc tgtatcatca
    53101 cgctcatttt taggaggttt agtcaagtct tcttcatcat acttatcaat atagttatgc
    53161 aaagctaaat aatctacatt ctcataagct tcttctaatg cgatacgatc ccattcaggg
    53221 tacgatggta aacgtggcgt agagcttcca actaagattg tttcaattga atcatccact
    53281 aacttcatga cttttgaggc ttcatttgct aacctaccat attcataagc actcttagcc
    53341 cccacttgcc atggaccgtc tagctcattc cctaaacacc ataatttaac gccaaaaggc
    53401 tttttttgcc cattttttat tcttaaatca ctccagaagg ttccttttgg aaaattacaa
    53461 tattctacta aattttttgc ttcatcaatt ccttttgttc ctaaattcac cgtgaatatc
    53521 ggtttcgctt gtacatgact gatccattta aaaaattcgt ggagtccaaa agaatttggt
    53581 tctatacctc gccatgctaa atcaattttt tttggtcgtt gttctttcct acctacagta
    53641 tccacccaat cataaccaga tgtaaagttt cctccaggat agcgaatgac acctaattct
    53701 aattccttta cataagagag gacatcttgt ctaaacccgt caccatcagc tgtttcatgg
    53761 cccggttcat aaatccctgt atagacgaca cttcccatat gctcaacaaa tgagccaaac
    53821 agccgagaac tgatctctcc taccgtaaaa tcctctctga tttttacttt cacttcttcg
    53881 tccaacagct ttccctacct ttcatttcct atagtcaaga taatagatac aagtttccat
    53941 acgccaccag caaagataaa aataaaagga gggaaaagaa atatgagcag tacaaatcct
    54001 aataacaata cgcaacaaag aatatttctc aaaaaatcaa aaaatacttt ccatgcactt
    54061 tgttcaaaaa tttgtaaaaa tgtgatatct ttgttttcag aaatcacata tatccaggat
    54121 aaaagaaaca tggaataaat aagtaaaact acatatccac taattgaaag tacgattgtc
    54181 tgttcttcta ataattgatt aacaagaaaa taaataatga tcgttaacag actaaggaac
    54241 aagttcttac caaaatgttg ctttattcct tgaaagaaaa aataaatgat atttcctgat
    54301 ccctcacctt tccattgcgc cattacataa aaaacagcac atgtagcagg cacgatagta
    54361 ataacaggca aacacacgat tacccagaga atacctaata agatgtaatc agaaaccaca
    54421 atcaactgtc cataaagttt agtctcaact attttcatct tcctcactct ttcattccag
    54481 acatagctgt tccttgaaca aaatatttct gtgcaaaaat ataaaccact agtaatggca
    54541 gcattgaaat aaccgttcca gccattacag gtccataaaa agaaatgttc tgccctgtaa
    54601 ataaagctaa ccctgctggt aaagttctca tttttgaact acttgtcaat atcaatggat
    54661 aaagcaagtc attccaacta ttcatcagcg tgaaaatccc taatgataaa agagtaggtt
    54721 tgctcaatgg caacatgatt ttcaaaaaaa tattaaactc acttaatcca tcaatgcgtg
    54781 ctgcctcttc caaagaatct ggtaaagtaa taaaaaagga acgcatcatg aagataccaa
    54841 atgcagttgt catacgagga atgatcaaac ctgcataagt atcaagcatg ccaagcaaat
    54901 tgacttcaat aaatagagga atcatgaaga cttggaatgg gatcatcatt gtcagcaaaa
    54961 cgaaatagaa caaaactgat tttcctttga aacgcatacg agcaaatgca taccccgcaa
    55021 gagaatcaaa gaatacagaa gtgatcactg tccctccagc aaaaatcact gtatttttga
    55081 tgtaatctaa taaagggatc gttgtccaaa ccttaatata gttatctagg gtatagctat
    55141 ctgcaaatat tctaggcgga aatgagataa tgtctttttc gtgtttaaaa gaagaaataa
    55201 tcagccacaa aaaaggaaac gcaataacca acaatataac tagcatacta atcgttcgaa
    55261 tgattttttt accactaact gcttttcgac tattcacagt aactgtaatc gagctttctg
    55321 gtgccataca ggtttccctc ctatttcatt tgtttttctt tccgtgacat gtacacatta
    55381 gtggagatag ctatagttgc aacaatgata aacaaaaccg aagacagtgc tgatgcatag
    55441 cccaattcat aaggtgctgt aaatcctcga ctgtaaatat attgaacagc tgtttctgtc
    55501 ttaaattgtg ggccaccagc ggttgcaaca tatacttggt caaacacttg catcgaacca
    55561 atcagattcg ttaaaataca aaaacctaag gagggaacga tctgaggtag cgtaatgtta
    55621 aaaaactgct gtcgatttgt tgcaccatcc atttgagcag attcatacaa agagggagag
    55681 attccctgaa tagcagtcaa gagaatcgtc atagtaacac caaaattctt ccaaacagtc
    55741 atgatggcta ccgtcggcat agcaagggtt ggatcgcgaa aaaattgagg gatcggcaag
    55801 ccgacttgtg aaaacaagta aggaatcgcc cctacattcg gatcaagcaa catagaaaaa
    55861 ataatcgcaa ttgacgtcaa tgaacaaata actggaatgt aaaatgtcga acgacaaaaa
    55921 cgattgaatc tggtattttt agataatgct actgctgcta ataaaccaac gataatttgt
    55981 gttggcgttt cgagtacggt gaaatataaa gaatgaatca acgaattaac tgctcgttca
    56041 tcactaaata tacgtgtgaa attttcaaaa cttacaaaat ttcttgatgt aaagaaaata
    56101 ttcaaatctg taaaactaat agcaaatgtt cctaaaagcg gtatgacagt aaataataat
    56161 aaaactaaaa aagatggagt taaaaacaaa tacgcagcac gatcaggacg attccaatat
    56221 ttggtgaatc cgttcatata gtccacctca tctttcattt tgataaaata tacaatcttg
    56281 gtttaaacga atctgaataa gatatccgaa caatcgctgt gatttttgca ataacaccta
    56341 tctgcaaata ctaggtcgat cattcagata tctgtatctt gccaacagtc tatcctgtat
    56401 aaagttctgt actatttttg cagtaattga ttgatggcat catctgcatc gttcatgagt
    56461 gtctcaggat cttctcctgc taataatttt tcaatcagtg gattgatgat atcgttattg
    56521 atcgcagaga tttgggtaaa acctggtaaa tatggctctg catagtccat ttgtttcgat
    56581 aattcagata caataggatc attttttact tcttcatctt ttgctactga atccaagtag
    56641 gcaggaaaac cattttcgat actccatttt ttaccaattt cagttgtatt ccaatatttc
    56701 aaaaactcat agacagcttc ttttttatta ttatctgtac ttgccggaat ggcatatcct
    56761 acgccatcta aaatagctgt ttttttgtct gaatcactcc cttgtggtaa ggtagtcaca
    56821 ttataatcaa tctcgtttgc tttcaatccg ttatttaacc atggcccatt gatttcaatg
    56881 gctagttgac cagcattcat taaattgtcc atttcggcgc cagaaatcga ttctggacca
    56941 gtcttgtcta catggatcat tttttggatc gcttttaacg ttttaaggtt ctcaggagac
    57001 gcaaattcag acttagtata atcatcgttc actaatttac cgccatttgc taacatccag
    57061 ttatataacg gtgcagttcc atccttattg aagacaaaac ctgatacatt tttactacta
    57121 tcagttaatt ttggtgccat ttctgtcaat tcttcccaag tagtaggtgg ttgttcagta
    57181 tctaatccag cttgtttaaa caaatcatta ttccaataca tatacatgcc ttgtacctgc
    57241 atggggacaa aatactgttt accttctact tcacctaatt caatagccgt ttctttaaaa
    57301 tcagatttat ctactccatc atattcccag aaatcgtcta atggttgtac cgctccgttt
    57361 tctacatact gtgcaaaatc tggataattt aatgcaataa agtcaggtgc ttttttagaa
    57421 gaaatcgctg taggaagttt ttcattcaaa ttggcccaag tcatgatatc catttcaatt
    57481 ttgatgtttt tatcatttgt tttattaaat tcattaacga tttcttgcaa tatttcacca
    57541 tcagatgcag taaacccatt ccaaaaagtc aaagtcactt ctttatcaga atcagattct
    57601 gctgaacttc cgccaccgca agctcctaaa atacctgttg cagctaccaa caaagagcca
    57661 attaaccatt ttttaccttt cattttttgt tcctccttca tctgataaac gacatctgac
    57721 cacattccaa gatagcggtt tcaataaaca attgattttc ccatcttcag cttttacatt
    57781 tgttgaatga cttggtttta cttgttcact tttaggaaga ttagttgctt ttgtatcaaa
    57841 tccactcatt tcagaaaaat caatcactcc ctctaatgat aattcagaca agtgaacagt
    57901 tagattcatt tcttcttctc cacggttaac tgcaaatatg acaagttctt tgtcatttat
    57961 tacggctata ctttctaaat acggcacttc ttcaaaatct tccgtcgcat agtttgctga
    58021 acgaatttgt gggcttaaca cctctccttg tccatacaca gcagcttgca taaatggata
    58081 atagatcgtc tgtctccaag cttctccgtt tgtttctgtc ctgattggtg caataacatt
    58141 taccaattga gcaagacaag caatctttac tctatctgca tgtttcaata aagtgattaa
    58201 tagacagcct aatagtaatg catcttcaaa attatagtta tcttctagta aaggaggagc
    58261 aatctgccaa ggcgctgctt gctcatcttg ttccgctgaa tgataccaaa tattccattc
    58321 atcaaaggac aggttgatct gcttcttact atgtttcttc gccttgactg tatcgcacat
    58381 cgctgtcact tcagaaatga accgatccat gtctaaggaa cgtgcaagat aatgagaaag
    58441 atcatttttt tggttgccat aatattgatg cagagacaaa taatctattt gatcgtacgc
    58501 ttgatcaaga actgttaact cccaatcacc aaatgtaggc atttgccgat tcgaacttcc
    58561 gcataaaacc acctcaattg aatcatctac gagtttcatc gccttagccg tttcctctgc
    58621 taaccgtcca tattcttccg ctgttttatg tccaatctgc caaggaccgt ccatttcatt
    58681 ccctaaacac catgtcttaa ttccaaaagg gctctcttga ccattcgaac gccttaaatc
    58741 actccaataa gttcctttag gaaaattaca atattcgact aaattacgag ctgcatctac
    58801 tccacgagta cccagattga cagccatatt gatttcggcc cccacatgct gacaccagtt
    58861 ataaaattca tgaatcccaa cttcattcgt ttcaattgtc cgccaagcta aatccaacct
    58921 tctaggtcta tttgctatgg gcccaatact gtcttcccaa cgaaatcctg acacaaaatt
    58981 tccaccagga tatctaatca tgggaatgtt caattctttt accaagtgaa tgacgtcttg
    59041 gcgaaatcca cttttattag ctgatggatg atctggctga taaatccctt catatactgc
    59101 tcgtcccata tgttcaataa atgaactgta caaccgcgga tcaactttgc ctacacgctt
    59161 gacactacta atcaacattg tggcttccat aactgacctc ctttaattta tacatgaata
    59221 atacacctcg ttgaaagcgt tgtcaataat ataaatgtta aacttactta ttttttatcg
    59281 attttaatta accaaaatat taataatgat taaaacaaat aatttaatat aacttttatt
    59341 aacaaatatg ttaatatata agaaaaacct tttaagaggt gatatatatg caactacaaa
    59401 taaacgaaga atccttaccg gtatatgaag cattagctag taaaacaagg atcaagatca
    59461 tccagctact ttccaaaaaa aagatgaatg tcaaagattt ggcaaaagaa cttggagtga
    59521 gcagtgctat cacgacgatg cacgtgaaaa agctagagga agcaaacatc atcaaaacag
    59581 aaaaagtagg acaacaaaaa atttcgagcc ttcgtgtcga taaaatcgat atcagttttc
    59641 cagaaaaaat attcaatgct tttgatacga aagaaacatc gatacctatt ggtcactata
    59701 caaattatgc aattgaacca acatgcggtt tagctacgat ccatgatttt atcgggaaag
    59761 tggatgaacc acgctatttt atggatcctc gaaggatgga tgcccgcatt ctctggttta
    59821 ccagcggatt tgtcgagtat caggcaccta attttttaaa tacagaggat acattggaga
    59881 tgttggaagt ttctgtggaa atttcttctg aatttccttt ttcaaatgac aattggcctt
    59941 cagatatcac tttcagccta aatggtgtgg agctaggaac atggacgagc cctggagatt
    60001 ttgctgatat ccgcggtaaa tatacgcctg attggtatcc agataatctt aatcaatacg
    60061 gcttgctgaa gacgatccga attaccaaac acttgacgaa tatgaatgga gaacccttgt
    60121 caaacatcac gatcaacgac atccctaaag agcaagacac ttggcatttg cgaatcgaag
    60181 tgaaagacga tgccaaacat gtggggggct gtactttatt tggtaaagga ttcggtaatt
    60241 acgatcagga tatcaaatta aaagtttact acagctgata tttttctttt ctattttata
    60301 aaacaaaaac agccaatccc tatgaaggga cggctgtttt tgctttattg ttatttccag
    60361 aaatcatcca aaacggaaat tggcaaatgt cgtttatgtt gtgtcttgtt ccaccatgct
    60421 tcgatttttt cttgtgcttg agcgggaact tcttttcctt ctagataatc atcaatttca
    60481 ttatatgtga cacctagtgc gacttcatct gcaatcattg gtttcccatc ttcaagatct
    60541 gcagtcggaa tttttgtgta taatttttcc ggtgcattca atgcttgaag caattgtttc
    60601 ccttgtcgtt tgtccaaacg gaataatggc aaaatgtcgg ctccaccatc accaaatttc
    60661 gtgaagaatc cagtaatgtt ttctgcagca tgatctgtcc ctaatacggc tcctgctctt
    60721 tctccagcta cggcatattg cgtaatcata cgttgacgtg ctttgatatt tcctttgtta
    60781 aaatcgctga ttcccacacc tgcttcgctt aatacttgta cttgtgcatc aacagctggt
    60841 ttgatattta ctcgcagact aacatcgggc tggataaagt caagagcagc ttttgcatct
    60901 tcttcatctg cttgttcacc ataaggaaga cgaacagcga taaattgata gttttcatct
    60961 tttgtttctt cacgcatttc ttccatcgtt agttgcgcca aacggcctgc taaagtagaa
    61021 tcttggccgc cgctgatacc tagtacaaaa gttttaagaa acggatattt tttcaaatat
    61081 gctttcataa agtcaatact tttacgtatt tcttcttttg gatcaattgt tggtttgaca
    61141 cctaattcat tgataatttc tgtctgcagg ctcatttatt ctcctcctat gcttctgtat
    61201 gaagttctgc tacgcttttt ttcattcgtt ccatgatagc cattttatgg ttccagcatt
    61261 cagtagacag atcgactggg tatttttgcg gattcaagtc tcgtttatac tcttcccata
    61321 gtgaatctag attttctttt gtatattctt tgatttcgtt tagtgcaggt aattcgtaaa
    61381 ctctttttcc ttcgataaag atatcttgta aaactgggcg agctgtaaag tctcgaacag
    61441 ttttattgat aaacgtatgc actggatgga acatgaagat agcttcttct tctcgagggt
    61501 cttcatccca taatgtcacg tagtctcctt cagatttccc atcaaaattt cgagtgatgc
    61561 gccacacttg ttttttccct ggagtagtta ctttttctgc attgcttgat aacttgatcg
    61621 tatccatcat ttttccttca tcatcttcga tcgatactag cttgaatact gcaccaaggg
    61681 ctggctgatc ataggctgtg atcaattttg tcccaacacc ccatacatca attttagctt
    61741 tttgcatctt taaattcaaa atcgttgctt catccaagtc attcgaagca tagatttttg
    61801 cttccgtaaa tccggctgca tctaattgtt cccgaacacg cttagatata taggccatat
    61861 ctccactgtc gatgcgtacg ccttggaagt tgattttgtc acctaattct ttcgccacgc
    61921 gaatcgcact tggcacacct gatttcaacg tatcataagt gtcgactaag aacacgcagt
    61981 ctttatgggt tttagcgtag gccataaatg cttcataatc atttccataa gattggacta
    62041 acgaatgagc atgggtcccg ctagctggta tcccaaatat cttcccagca cgtacattgc
    62101 ttgttgcatc tgctccgccg atatatgccg ctctagttcc ccagactgct gcatccagtt
    62161 cttgtgcccg tctagttcca aattccaata gtggatcttc tccgatgaca gatttgatac
    62221 gagctgcttt tgtcgcgatc aacgtttgga aattgaccat attcaacagt gctgtttcta
    62281 ctaattggca gtgcgctaaa ggcccttcca cttggattaa tggttcattt gcaaaaacta
    62341 gttctccttc acgagcagaa cgaactgttg ctttaaattc aaaattttgt aaatactcca
    62401 aaaaaccttc aggatagact tctaatccac gcaagtaagc aatatcggaa tcattgaacg
    62461 tcagattctc taaataattg actaaccgtt ccaatcctgc aaaaaccgcg tatccgtggt
    62521 taaaaggcat ttctcgaaag taacattcaa aaacagcatg taaatcagct cgacctaatt
    62581 cccagtatgt ctgcatcata ttgatttgat atagatccgt atgcagcgtc aaactgtcgt
    62641 ctgggtaagt attattcatc ttgtattact cctcttggca agttttcatt tcctacccat
    62701 tataacaaaa aaaattaata ggaaaagaaa tcttccattt tttctgaaaa agcacatgtt
    62761 ttacggatat ttcttgctaa aaatgaactc catctgctaa aactatcctt tcttattggt
    62821 atttaaccta aacgagaaag aatacttatt ttattcaatg tatccgagac acgaagaaat
    62881 tagcgttttc tatttttctt acttgataaa ataagtagat tttcctacta caatcgtagc
    62941 cgttaagata ccgatgattg aacaaatata accaaatgtc tctacaacat aatcaatggc
    63001 aaaagttttt gaagcaataa tacgtctttc cttttttgct tcttatcccc aaagaaacgg
    63061 atataactta ttatgtattg aatttttttg gaaaggcgaa ttatgacaag atataccttg
    63121 cgttgaaaaa actcgcggaa aaaatatcac acgtttttaa aaagatacaa agtaagaaag
    63181 cagctgtcaa tagaatggaa acaaaaatgg cgagacatca atcagtctcg ccttgttttt
    63241 tattgtatac attagatatg gagcaggtta ccataaagat gattattagt cgttattaaa
    63301 tagaatcctt cgtatttttt tgttctatca ctacaatatc tttatttgga cgtttgaatt
    63361 gtattccggc acgttctagc tcctgtttca ctcctacatg gactttgaca tcttctcgtg
    63421 tcatttttaa aacgtgatga atcgcatagt cgatttcttg ccttgtgatt tttttcttcg
    63481 tattgatcat cacgacttgc tttttatcat atgtgtctac caatagcagt tgtgttcgat
    63541 ctaacgaaaa taatttgtaa taattaatag ccgtattccc aaaaaagaat tccactactt
    63601 taggataaaa tgtcttaata tttaaattac tattcacagg tgtttcgatt agcttcatct
    63661 cattcctctt ttctatatag tcgatttaga tccaatctta agttatgtta ccatctttcc
    63721 tagcattaag gaatcggtta caattgaacc tttaaagaca aaaggattta ccttttatca
    63781 cttaatagta taacataatt tcgtgagaaa aaaatacaat tttttcttga ccatctcgtt
    63841 acgtaaagga ttatgcttac atttgtcagg aggaaaaata atggagtaca caataaagaa
    63901 aatgtcagag atatcaggag tcagtccgag aaccttgcgc ttttatgatg agattggact
    63961 gctaaaacca gctaggatca attcttcagg ttatcggatt tatggcaaaa aagaagtcga
    64021 tcgtctgcaa cacatcttat tttatcgaac aatggcattc aagttggatg atatccaaga
    64081 ggtcttagac aatccatctt ttgaccacca gaaagcttta atcaagcatc agcaaatgtt
    64141 gctggaaaaa cgggcacaaa tcgataccct cttgacaact gtccaacaga cacttgatat
    64201 gtacgaagga ggaagaaaaa tgagtgacaa agaaaaattt gaagggttta aacaacaaaa
    64261 gttgaaagaa aatgaagaat cctatggaca agagattcga caaaaatacg gaaaaaaaaa
    64321 ggttacagca tccaatgaaa aatggatgaa tatggataaa gaaacgtatg aagaaatgca
    64381 aactgttgaa aagcagatgt tatttgatct cactctttac ttaaaagaac cagaagatga
    64441 aagcttagca gaccgtatct tccaagctca taagaagtgg ttctcttaca gctggcctga
    64501 atatcagcca aaagcgcata aaggactagg aatgatgtac gaagccgatg aacggttcac
    64561 tgcatattat gacgagcgaa gtggtcatgg tgcagcaaaa gctttaaatg aaattatcca
    64621 aaaaaaggcg taatctttta catgatccaa caaaaaagta cacgtaaaat gacctaataa
    64681 caaaacagca gacacccaag ttagattttt atgctaactt ttggtgtctg ctccattctt
    64741 tcacaagttt tttcatccta ctttaaatat attcatcgtt gaataaacgt ataaggtatt
    64801 ttcactttat cctttttttc tgtaagaaac aattgaaatg ccatttctcc gcaagcttcc
    64861 agatggtggt cgatggttgg gaaaccaaga agctcgctga tcagcaaatt atcgcgtcca
    64921 atcaccactg gtgtcttatc ttgcagatag ctttgcaaga tgcctgctgc aaccatatcc
    64981 gaatttgtaa agacaccatc aactccaagc tctttaaaaa agaagcctgc ttgttttcct
    65041 ttctctgcat ctatacaatc ccaaaaaaca agtgattcat caaaagatgg aaaaagttga
    65101 tgacatagct gcaaagtgat ttttgagtta taacttagcc tgccacttcg ccccaacgtg
    65161 atgcccaatt gctttatacc ttgctgcttc aaataagtaa gaccttctgt aattgattgt
    65221 tctcgatcaa taaagacaca gcttgcctgt tttcccttga tttcttcaca aaaaactaga
    65281 ggtccatatt tttgatatgc caataaatca tctagtgtat tggcacgaga cgtaatgatc
    65341 aatccatcga aagctttagc tgcaaattct tcaagatacc ttcgctcttt ttctttatga
    65401 tagcccgtcg gtaaaagtgt cactttgtaa tcataatcaa acgctgcttc aatgatccca
    65461 ctgatcaact gatcaaaata cggatgattg gtataaggca gaatcactcc aatgcttttc
    65521 gtttttccat aacttaactg tctggcattt gcattaggga tataatcgac ttctttcatg
    65581 accgcaagta tttctttcct tttttcctca tctacatatg gatgtccatt gattacacgt
    65641 gaaatagtag aaactgaata acctgtgagc tttgcgatat ctcgaatgtt tgccactgct
    65701 gcttcgccac ctatacaaaa agattttctt gtaaatagtc taccacagct ggaccgcatt
    65761 caaaaaactg atacattttt ccttcatgcg aaaaactgat ccgctgcccg ccccaatata
    65821 tatcttttgt caaattttcg atttcattca ttggtatttc ttttactata ttcctattca
    65881 acccttgaaa actgtacaac gttaatacgg atcccttgaa ctcgacaaac gcataaaaat
    65941 aattgttcgt tgtgccatct gttatctcta cataagtatt cattgcaagc cctccttttg
    66001 atactttgag tatagtgtat gaaacgcgtc tcatagcaag gagtttgttt tgccaaagaa
    66061 aagttttatt cctctttcat tattaccaaa gtctcttatt ttaaattgaa tacattataa
    66121 tgatactgta aatatatctt tattattagt gaatg
//
LOCUS       DAPBBV010000010        65599 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.010, whole genome shotgun sequence.
ACCESSION   DAPBBV010000010 DAPBBV010000000
VERSION     DAPBBV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 65599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.010"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(176..2347)
                     /gene="copB"
                     /locus_tag="RD486_000841"
     CDS             complement(176..2347)
                     /gene="copB"
                     /locus_tag="RD486_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HDT7662593.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(2367..4553)
                     /locus_tag="RD486_000842"
     CDS             complement(2367..4553)
                     /locus_tag="RD486_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDT7662594.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(4553..4762)
                     /gene="copZ"
                     /locus_tag="RD486_000843"
     CDS             complement(4553..4762)
                     /gene="copZ"
                     /locus_tag="RD486_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HDT7662595.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4775..5215)
                     /locus_tag="RD486_000844"
     CDS             complement(4775..5215)
                     /locus_tag="RD486_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HDT7662596.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5289..5828)
                     /locus_tag="RD486_000845"
     CDS             complement(5289..5828)
                     /locus_tag="RD486_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HDT7662597.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(6443..7909)
                     /locus_tag="RD486_000846"
     CDS             complement(6443..7909)
                     /locus_tag="RD486_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7662598.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(8220..10301)
                     /gene="cadA"
                     /locus_tag="RD486_000847"
     CDS             complement(8220..10301)
                     /gene="cadA"
                     /locus_tag="RD486_000847"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDT7662599.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(10825..11184)
                     /locus_tag="RD486_000848"
     CDS             complement(10825..11184)
                     /locus_tag="RD486_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HDT7662600.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(11214..11555)
                     /locus_tag="RD486_000849"
     CDS             complement(11214..11555)
                     /locus_tag="RD486_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662601.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(11552..12226)
                     /locus_tag="RD486_000850"
     CDS             complement(11552..12226)
                     /locus_tag="RD486_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7662602.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(13403..14701)
                     /gene="asnS"
                     /locus_tag="RD486_000851"
     CDS             complement(13403..14701)
                     /gene="asnS"
                     /locus_tag="RD486_000851"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDT7662603.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(14741..15931)
                     /locus_tag="RD486_000852"
     CDS             complement(14741..15931)
                     /locus_tag="RD486_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7662604.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFLKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(15952..16479)
                     /locus_tag="RD486_000853"
     CDS             complement(15952..16479)
                     /locus_tag="RD486_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HDT7662605.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(16526..19315)
                     /locus_tag="RD486_000854"
     CDS             complement(16526..19315)
                     /locus_tag="RD486_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDT7662606.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFIYVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGTGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMTTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(19462..19662)
                     /locus_tag="RD486_000855"
     CDS             complement(19462..19662)
                     /locus_tag="RD486_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7662607.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(20114..20434)
                     /locus_tag="RD486_000856"
     CDS             complement(20114..20434)
                     /locus_tag="RD486_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662608.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(20818..21936)
                     /locus_tag="RD486_000857"
     CDS             complement(20818..21936)
                     /locus_tag="RD486_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662609.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            22441..23715
                     /locus_tag="RD486_000858"
     CDS             22441..23715
                     /locus_tag="RD486_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDT7662610.1"
                     /translation="MASLILCLASFLPAVAVQAEDTFKVNAKAAFAVDAQSGKILYDQ
                     DGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSITPDLSNVPLHKE
                     NTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWGIKDATIVNASG
                     LNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSSTTTQMFGENTQS
                     PVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRIITVVLNADGHA
                     ENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKESTVPVVLKSPVK
                     VWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLADDKLGYLEDNNA
                     PSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            23834..25033
                     /locus_tag="RD486_000859"
     CDS             23834..25033
                     /locus_tag="RD486_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDT7662611.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYAWQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(25060..26328)
                     /locus_tag="RD486_000860"
     CDS             complement(25060..26328)
                     /locus_tag="RD486_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HDT7662612.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(26491..27138)
                     /locus_tag="RD486_000861"
     CDS             complement(26491..27138)
                     /locus_tag="RD486_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HDT7662613.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALATEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMIYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(27546..28049)
                     /locus_tag="RD486_000862"
     CDS             complement(27546..28049)
                     /locus_tag="RD486_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7662614.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(28172..28936)
                     /locus_tag="RD486_000863"
     CDS             complement(28172..28936)
                     /locus_tag="RD486_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDT7662615.1"
                     /translation="MKEIQSAKNPKIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            29044..29319
                     /locus_tag="RD486_000864"
     CDS             29044..29319
                     /locus_tag="RD486_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDT7662616.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            29757..30707
                     /gene="yidC"
                     /locus_tag="RD486_000865"
     CDS             29757..30707
                     /gene="yidC"
                     /locus_tag="RD486_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDT7662617.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(30886..31860)
                     /gene="lacD"
                     /locus_tag="RD486_000866"
     CDS             complement(30886..31860)
                     /gene="lacD"
                     /locus_tag="RD486_000866"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDT7662618.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPECGLPAAALREKECGLLLAYEKTGYDTKMPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECDAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLKETATPVYVDR"
     gene            complement(31857..32315)
                     /locus_tag="RD486_000867"
     CDS             complement(31857..32315)
                     /locus_tag="RD486_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7662619.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKEVYRK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(32312..33775)
                     /locus_tag="RD486_000868"
     CDS             complement(32312..33775)
                     /locus_tag="RD486_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7662620.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTILADNEAVDTLESETISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMLKTVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     SGGTGFLVGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVVFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPINKAAYVTGTALLAQGN
                     TTFMAGVSVACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEEGRAGGLS"
     gene            complement(33757..34707)
                     /gene="pfkB"
                     /locus_tag="RD486_000869"
     CDS             complement(33757..34707)
                     /gene="pfkB"
                     /locus_tag="RD486_000869"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDT7662621.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQKKQIQTEFIEVPGMTRINVFTQVNQTREE
                     YKLVNQGPEIPQAAVHNFLNQIRALQAEDYLCVSGSLPRGMSPKVLVEISRICQEKEI
                     HLIIDSSDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENV
                     LLSLGEKGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLVGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            34850..35598
                     /locus_tag="RD486_000870"
                     /pseudo
     CDS             34850..35598
                     /locus_tag="RD486_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            35864..37342
                     /locus_tag="RD486_000871"
     CDS             35864..37342
                     /locus_tag="RD486_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HDT7662622.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRVESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(37410..38501)
                     /locus_tag="RD486_000872"
     CDS             complement(37410..38501)
                     /locus_tag="RD486_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HDT7662623.1"
                     /translation="MLKKNTSLQNKTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFLFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
     gene            complement(38539..39708)
                     /locus_tag="RD486_000873"
     CDS             complement(38539..39708)
                     /locus_tag="RD486_000873"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7662624.1"
                     /translation="MKKVTILIPGMYYGGMERVAFITRQILLKNNYNVSFVTLFDNDA
                     DYQPNFEYLSLKCDIKPSKFGKVINIFKRVYKMKSVKKKLKTDITISFGQSCNLVNVL
                     SKRDDKVYVGIRSYDWLFQYIFHYYVDKFVYKKADAVVSVSQLIKRDAENIFNFNKDK
                     SYFLYNPYDLELINNKSKEKITEIEVPTDKKIIVTVGRLEDQKGLYHLIKAISMLKNK
                     DNVVVYILGHGTKKELLENLIKAYQLQNVIFLLGGQSNPYKYMSRADLYVMPSITEGF
                     PNALVEAMSTETAVLCADCKSGPREILSNRTLDTICENIEYAESGILVCPMTDSRNYS
                     PQYEECDKNLANAIEELIENDNLRNKYAKAAKKRAELYSYDAFEHNLLQIMKTFN"
     gene            complement(39743..41200)
                     /locus_tag="RD486_000874"
     CDS             complement(39743..41200)
                     /locus_tag="RD486_000874"
                     /inference="COORDINATES: protein motif:HMM:NF024832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDT7662625.1"
                     /translation="MGNNIHGKTAKALKWSSLAEIIAKIITPISNMILARLLTPDAFG
                     VVATVTMVISFADMFSDSGFQKFLVQHEFDNEEHMFSSTNVAFTSNLGISLLLWLFIC
                     VFNNKIAHLVGNSGLGLVIIVAGVSLPITSFSSIQSAIFRRNFDYKILCYARIISALI
                     PLVITVPLAIIGLSYWSLVIGSIIGNLVTAAILTKLSEWKPKLFFSKKEFYEMFSFSA
                     WSLVESLGTWLSSYIGTFIVGGILSVYYLGIYKTTMTTVNGIFAIVTSATTTVLFSTL
                     SRLQNSKTEYDKTYLDFIKIVSIFIIPLGIGIYVYRELVTNILLGSQWKEAVPFVGIY
                     GLMSCFTLVLGQYASEYYRGLGKPKANVLMTILHLAVLIPVLIIYSRKGFIELAYGRS
                     FVKIEQIIVFWIILWFGFKFNPFKILKQVWKSCASALLMGVLAKIMLEFCTNYVMQLL
                     SVCLCVILYFFIYSCIFKGKTEIINMVRMFTGKGY"
     gene            complement(41259..41720)
                     /locus_tag="RD486_000875"
     CDS             complement(41259..41720)
                     /locus_tag="RD486_000875"
                     /inference="COORDINATES: protein motif:HMM:NF012360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HDT7662626.1"
                     /translation="MRRKAEKWADKACRQYRNGQNKMSKISCYILRIIYGCEFYGQVD
                     FSSNAQLVHNGLGCVFHPKTKIGNNCKIYQNVTLGGNGKIINGKETVGAPTLEENVAV
                     FAGACVLGPINIGHDSIIGANAVVTKSVPPYSLVYGNPAIITELKFDYKFD"
     gene            complement(41731..42507)
                     /locus_tag="RD486_000876"
     CDS             complement(41731..42507)
                     /locus_tag="RD486_000876"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDT7662627.1"
                     /translation="MAFQVYLQRVYILSTGVIIGHYAEMGLNRIAYAGLMGDFSFAGL
                     YLATGCLYAFLKYVDLKNWKLLFFIIIEVFLLGAILCVSARTGLVSLFVTMTLYYLFN
                     INRISVPHLLVLIGGIITTPYILVMLMAGRSGQSLLDSSGRLENYMSSLNAFSDKYLI
                     GYGLGLNNLYTLLGVAVPHNFFIQYLLQTGIIGTLIILSGFFKFTYEELKKSGCYKWL
                     FLMIVVGAMFIPDIVSSRFLYAIVVLCMISASERTIKKES"
     gene            complement(43036..44088)
                     /locus_tag="RD486_000877"
     CDS             complement(43036..44088)
                     /locus_tag="RD486_000877"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7662628.1"
                     /translation="MKKIKIMHLLQSNRFSGAENIVCQIMSLFQNNEKFEMIYVSPDG
                     PIANILNIRGLSYLPLKKFSRKEIDRAVHELNPDIIHAHDFNASVRASRYKKQIILSH
                     LHNNPLWLPKLDIRTIIYSLCSSRFNSVIGVSNSVKEEFRYKQLIKDKFVLLPNTVNT
                     ERIIKMGNEFVEDDIDILYVGRMAEPKNPIGAINVLENVVKKYSKHLRVVMIGEGPLF
                     DEVKMQIQKRNLTDVIELKGFKSNPYKYMKKSKVLLMPSLWEGFGLVSVEAMLLETPV
                     VAYNVGGLKDIIDETNGFLCGSEVELSNSLMKLLNSEELRKKMGENAAISAKKFSNMN
                     RYQGVLEKIYVSAALK"
     gene            complement(44111..45256)
                     /locus_tag="RD486_000878"
     CDS             complement(44111..45256)
                     /locus_tag="RD486_000878"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF024831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7662629.1"
                     /translation="MKLLYILNVANKVNNFSKASMMAAKQTGLEFYIAGNWKYKSDEE
                     RKADEVKYGIKIYQVDFYRNPLNLKNIKAYHQIVEIIKNEKIDIIHCNTPIGGVVGRI
                     AGLKCKVKKVIYQAHGFHFYSGAPKINWFIYYPMERWLAHYTDVLITINHEDYTLAQK
                     LRLRKGGKAYYIPGVGIDTNRFMSSTSIRNFRESICKELNIPDTAKIILSVGELNENK
                     NHLSVIHALQKIPLHTDIYYIIAGVGEMRETLQNIANELGLHQRVFLLGYRSDIPKLL
                     AAANIYILPSLREGLNASLMEAMASGLPCIVGNIRGNVDLIEDGKGGFLINPKDEEEI
                     AGAINRLADNKLLCESMGAHNLDKIKDFDLSVVINQINNVYHEIVSK"
     gene            complement(45259..45870)
                     /locus_tag="RD486_000879"
     CDS             complement(45259..45870)
                     /locus_tag="RD486_000879"
                     /inference="COORDINATES: protein motif:HMM:NF012792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662630.1"
                     /translation="MVIEEIKSSDKELINSIVDIHMRTFTNFFLTFMGKKFLELMYRS
                     YTEYNDSGILVAIQNDKPIGFLAYSGDMSGLYKYMIKKRIIPFGFYSCVAFIKKPNIL
                     MRLFRAFLKPSETKRDENYVELASIGVNPKEKSIGVGSMLIDNLKSRIDFSKYEYIAL
                     ETDALNNDVVNNFYKKNEFILERKYSTNEGRIMNEYRFYMEKN"
     gene            complement(45887..46621)
                     /locus_tag="RD486_000880"
     CDS             complement(45887..46621)
                     /locus_tag="RD486_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDT7662631.1"
                     /translation="MRKWEDLPKEMQNDEIRYYYDILSKKKFSLVVKRVFDILVSATL
                     LLTLSWLFFILAIVIKIDSPGPVFYRQERITRYGKKFKIYKFRTMVINADKDGTLVTV
                     KNDDRITRVGKVIRKYRLDEISQLINVLVGDMSFVGTRPEVGKYVKSYSPLMLATLLL
                     PAGITSETSILYKDEDKLLHDKNNIDKTYIEKILPSKMYYNLKSISEFSCMNDLKIMC
                     KTIFVIFGKEYHADLEGEREFINQIK"
     gene            complement(46635..47858)
                     /locus_tag="RD486_000881"
     CDS             complement(46635..47858)
                     /locus_tag="RD486_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HDT7662632.1"
                     /translation="MNKLEKRQIPFSPPDITDLEIKNVVEVLKSGWITTGPKTKKLEK
                     KITKWLGTSKVVCLNSQTAAAETGLRLLGIGENDEVIVPAYTYSASASVVCHIGANLV
                     LIDCQQDSLEMDYDALEAAITEKTKVIIPVDLGGIPCDYDRIFEIVEKKRNLFQPSNE
                     IQKAYGRIIVMADSAHAFGANWHDQMVGNVADLTTFSFHAVKNFTTAEGGALVWKEHD
                     KLDNEAMYHQCQLLSLHGQSKDALTKTQLGAWEYDIVGPWYKCNMTDVTASIGLAQFE
                     RYPNILKRRKNIIKRYDEAFQQLGIEVLMHYTDDYSSSGHLYITRVPNISSEQRNEII
                     IKMAEQGIACNVHYKPLPMFTAYKNMGFDINNYPNAYAHFVNEITLPLHTKLTDEEVE
                     YVINNYSKIVKDLVG"
     gene            complement(47872..49689)
                     /locus_tag="RD486_000882"
     CDS             complement(47872..49689)
                     /locus_tag="RD486_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7662633.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISTGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASDVSSILILLFINRQYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIQVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESAHVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAKGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNK"
     gene            complement(49702..50466)
                     /locus_tag="RD486_000883"
     CDS             complement(49702..50466)
                     /locus_tag="RD486_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HDT7662634.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYKQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEIKKKKFGLF"
     gene            complement(50494..51192)
                     /locus_tag="RD486_000884"
     CDS             complement(50494..51192)
                     /locus_tag="RD486_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HDT7662635.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(51205..51984)
                     /locus_tag="RD486_000885"
     CDS             complement(51205..51984)
                     /locus_tag="RD486_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HDT7662636.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPTQPKATNDKTAPSRRSRSRV"
     gene            complement(52000..52944)
                     /locus_tag="RD486_000886"
     CDS             complement(52000..52944)
                     /locus_tag="RD486_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7662637.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(52985..53764)
                     /locus_tag="RD486_000887"
     CDS             complement(52985..53764)
                     /locus_tag="RD486_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662638.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
     gene            complement(54148..56223)
                     /locus_tag="RD486_000888"
     CDS             complement(54148..56223)
                     /locus_tag="RD486_000888"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDT7662639.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRVSRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQITAMALSL
                     ASLDQIITK"
     gene            complement(56225..57142)
                     /gene="glyQ"
                     /locus_tag="RD486_000889"
     CDS             complement(56225..57142)
                     /gene="glyQ"
                     /locus_tag="RD486_000889"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDT7662640.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(57526..58338)
                     /gene="recO"
                     /locus_tag="RD486_000890"
     CDS             complement(57526..58338)
                     /gene="recO"
                     /locus_tag="RD486_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDT7662641.1"
                     /translation="MSQLVESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(58481..59380)
                     /gene="era"
                     /locus_tag="RD486_000891"
     CDS             complement(58481..59380)
                     /gene="era"
                     /locus_tag="RD486_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDT7662642.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(59395..59790)
                     /locus_tag="RD486_000892"
     CDS             complement(59395..59790)
                     /locus_tag="RD486_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HDT7662643.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(59774..60250)
                     /gene="ybeY"
                     /locus_tag="RD486_000893"
     CDS             complement(59774..60250)
                     /gene="ybeY"
                     /locus_tag="RD486_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDT7662644.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(60267..62459)
                     /locus_tag="RD486_000894"
     CDS             complement(60267..62459)
                     /locus_tag="RD486_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDT7662645.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEVQEE"
     gene            complement(62483..63454)
                     /locus_tag="RD486_000895"
     CDS             complement(62483..63454)
                     /locus_tag="RD486_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDT7662646.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            64160..65539
                     /gene="brnQ"
                     /locus_tag="RD486_000896"
     CDS             64160..65539
                     /gene="brnQ"
                     /locus_tag="RD486_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDT7662647.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT        19099 a        13614 c        11033 g        21853 t
ORIGIN      
        1 gagtatccta cggatttaaa tcatttgaga acatgagaat tagaatcttt ttgatcaatc
       61 aattaatcaa agtaagataa caaaaaatct gagccagaat gaggttcatt ctgacccaga
      121 tttgattttg tacaacccat cagtccttat tgacaaagag cccctttttt cattattatt
      181 tgattttcaa tgtcaaagca tttagagcta caactaccgt acttaacgac atcaagacag
      241 caccaactgc tggacttaat atgataccaa ttggcgcaag aattccggct gctagcggaa
      301 ttgcaagaat attgtaacct gccccccacc agaggttctg gatcattttc tttcgcgttt
      361 gcttggctag atcaagaaaa tgcaaaatat cttttggatc gctgtttgtc aatacgacat
      421 ccgcagaatc gattgcgata tctgtccctg caccgattgc catcccgatt gaagcacggg
      481 ctaaacttgg cgcatcattg atcccatcac ccaccatgat tacttttttc ccttggtcaa
      541 ggtatttctg gacaacagct tctttatcat ctggtaataa accgccataa tattcttcga
      601 tccctaaata atctgctact gcttgggcag cgtttttatt gtcaccagta agcatgacag
      661 gagtgatttt tctttctttc aatgttcgga taaattcttt tgcttctgtt tttactacgt
      721 cacctaaagc aacgattgca gctagatgat tttctaaaat caggaagctg atggtatttc
      781 cttgttcttg gtaaggtttc aataatgctt gttctacgtt taatccgaga cgctcaactt
      841 ctttttcatt aactattttc acttgttgtt ttttgactgt tgcctctagc ccgactcctg
      901 aaagattttt tagattttca gcttgataag gcttgatttc atgttctttc aaataattca
      961 taatgccaac agccaatgga tgattggcat tcgcttccaa ggctcctaga tattgaagga
     1021 tttcattttt attgaacgca tcatcaagta cttcgacacc cgttacagta aattttcctt
     1081 ctgttagtgt tcctgttttg tccagcatga tcacatctag atcattggct tgctccagtg
     1141 cattgcggtt tttcaaaagt aatccgtttt tagctgctat tgatgtggag cgagcaacaa
     1201 ctaatgggat agctaaacct agagcatgag gacaggcgat gataaagact gttaccatac
     1261 gttctaatgc attaggaaga tctgtcaaga acaaccaggc gatgaatgcc aggataccca
     1321 caattaatgc gacataaaac agccattttg ccactttgtc agataatgac tctagcttgg
     1381 atttttctcc ttgtgctttt cgcaccattt ccataacctt cgctagataa ccattttcac
     1441 cagttccagt tacttcgatt tcgatcgttc catccccatt gatagaaccg ccaatcactt
     1501 tgtcattggc ttgttttttg attcctcttg attcgccagt cacagctgat tcgtcaacaa
     1561 ttgtttcacc tttcaagatt acaccatctg ttggcatttt atcaccagac cggacgatca
     1621 aacgatcacc ttcgtttact tctttcaatg aaactgtctc ttcttttcca tctttcgtca
     1681 agcgtttcac tgattctggc agtaattctg ctagtttttg taaagcattg ctggcattcg
     1741 acacagcatt catttcaatc cagtgaccta gtagcataat aacgatcaaa gtagccaatt
     1801 cccagaagaa atccatgacg tgtgtatgtg gattgagcag atttgcgata aacgaataga
     1861 cactataaat atatgcaact gtaatcccca tcgcgatcag tgtcatcata gcaggacttt
     1921 tttgtttcaa ttccatctta gctccactta aaaatggctg accgccatag ataaatagta
     1981 tagttgctaa gatcaatacg agccaatcag aaccaggaaa cgttacttga aatggaaatt
     2041 ccattcccat cattggtgaa aaaagaatga ttgggatagc taggataagc gatagccaaa
     2101 atttttgttt gaaattcccc atgtgcatgg aatgatccat gccgccgtgt tcgtgatcca
     2161 tgtgcatcga atggtccatt tgtttgctgt ttgctatatc tccatggtta tgtcccatgt
     2221 gcatggaatg atccatctga ctatggtcat gtttcatctc catctgtttt tcatgagatt
     2281 ctgtactttc tttgtttact acttcttttt tatgctcatg ttttttctcc atatcgttcc
     2341 cattcatttt tactccatcc cttctcttac tttttcatgt gtcgatttaa gctcagggag
     2401 ttcaacaata cactgacgga actaaacgcc atcgctcctc ctgcaatgat tggattcaaa
     2461 aagcctagtg cggcaaaagg aataccaatc gtattataga caaaagccca gaaaagattt
     2521 tgtttgattt ttctcaatgt caacctagac aactcgattg tttgtgcaat ggatgccaaa
     2581 ctgctattca tcagcgtcac atcggctgtt tccatcgcaa tgtccgttcc acttcccatt
     2641 gccataccga catcagctaa tgctaaggcc ggtgcatcat tgattccatc gcctgccata
     2701 ccgacttttt tgccatcttt ctgaagtttt tctacgtagg ctgctttatc ctctggaagt
     2761 acttcagcaa agatatgctt tggatcaata ccaacttgtt taccaatcgt ttcggctgcc
     2821 agtttgttgt ctcctgtcag cataaaaaca tctaatcctt tattctggag ctgcttgatt
     2881 gcttgtttgg cttctagttt gatttgatca gccacggcaa tccacccgat cacttgcttt
     2941 tcatcagcta aaaacatgac tgtttttccc tgctgttcta attctaacgc gtgttcttgg
     3001 tattcatcaa atgataggtt caattcaatt aatcgtttac gtgtacccgc aaaatagcgt
     3061 actccattaa tcgtaccgct gatcccagca cctgggtggg ctgtaaaatc aatcatatcg
     3121 tatgttgctg cttcttgcag ttttccgtat tccacgattg ctttacctag tggatgttca
     3181 gaagcttgtt ctaaagtata aaaaatagat aggacttctt ttgaaccgac tagatctgta
     3241 actttgggct ttccttctgt aatcgttcca gttttatcca aaacaatgct gtctaagtga
     3301 gcagctgctt ctaatgcttc tccgccttta attaaaattc catttcgtgc accaacaccc
     3361 gttcctacca taatagctgt tggggtcgct aaacctaatg cacatggaca cgcaatgact
     3421 aatacagaga cactatggat caatgcgagt tgccaatcac cagtgatcaa acctgtagct
     3481 atgagcgtga taaacgcgat gactaatacg atcggaacaa aaatccctga gatccgatct
     3541 gcgatttttt ggattggggc tttgctccct tgagcatctt ccaccatttg aatgatttgc
     3601 gctaatactg tctgcttgcc gacttgtgtg acttccatgt gtagcagacc attcgtattg
     3661 attgtcccgc caaaaagcgt gtcatccgga ttcttttcta caggaagatt ttcaccagta
     3721 agcatacttt catctatcgc actgcttcct gaaataattc gaccatctgc tggaatctgc
     3781 tcaccaggac ggatgactag ttgatcacca acgactactt cttcaatcgc taacgtttct
     3841 tctttcccgt ttcttatcac ttgggcggtt tttgtttgaa gagacatcaa ttgtttgatt
     3901 gcattacctg ttttcgtttt tgctgtatgt tccaaatatt tgccgagcaa aatcagcgtg
     3961 atgatcatac tgctgctttc aaaataaaga tcttgggggt gtccacggaa aaatccgttg
     4021 taaatgctca atgcaaaggc agccgatgtt ccaattgcta ccaatacatc catatttggt
     4081 gctttcgtct tgattgcatg gtacgcacct ttataaaaac gagcaccgac ataaaattgg
     4141 acaggagcag acagcactaa ctggacgatt ggaaaatgaa aaaagtgaac aatcgccgca
     4201 tggcttccta acatcatagc aatcattgac aacatcaacg gcaaagtcaa aaccgtactc
     4261 aatataagat cgaatagcat ttttttcaaa tacgcttgct tttcttctgc aattttttgt
     4321 ttgtgggctt catcgtacaa aattgcacca taaccgatgt tttctacgct ttggattaat
     4381 ttttcagtgg tcgtcccttc atatttgaca cttgcttttt cagtggccaa gttgactgtg
     4441 gcattgacca caccaggttg tccgttcagc tctttttcga tcctagcaga acaatttgca
     4501 caagtcatac ctgtaatgac gaacgtatcc attttggttt ctgctgttgc catcaaatca
     4561 cctctgcttt ataacccaat ccattgattg cttgacaaat cttttcggat tgaacttttg
     4621 tttcatcaaa cttgaccgta ccgtttgctt ttttcaaatt tactttcact ttttgcacgc
     4681 cgtcaagtgc gcttactgtt tcttctactc ttgctgcaca atgattgcag ctcatacctt
     4741 cgattgaaaa ttgttgtttc attttttctt cctcctattg atgttgttta cattcacatt
     4801 gacctgggat acagttacat tcgatcgtat ctactggttg cttttgttcc agttgtttca
     4861 aaatctcatt gatatcttct tgagtcaaag tggcttcttc tactagatcc gcaatcgtct
     4921 ctccaatcct ttttgcacag atatgggaaa aaagattttc cgtcgcactg cgaactgttt
     4981 ccatctccga gacagctgga tgataaatga atttttttcc ttcttgttct gtccagatca
     5041 cttctttttt taccaaacgt cccagcaaag ttttgatcgt tgctggtttc caatccatcg
     5101 aatcagctaa gatctgcgtg atttcttggg ctgtcgtctg tccaagtgtc caaataacac
     5161 gcatgatctc ccactctgaa tcactgatct ttactggcgt tttgactttt tccatttatt
     5221 tcacaccttt cgtttacaaa tgtaatcatt agcttatgaa tacagattac gcttgtaaac
     5281 aaaaactgtc aattattttt gctctctatt ttcaatttag ttaaaaattc ttgtttctct
     5341 cgtcttgttt taaggatgat cagtttattt cttgcattag ctacttggat cagctgctgt
     5401 attttcggtt cattgttttc ttcaaaatgc cagataaaag ataaaaattc taagtattcc
     5461 ctgtttagtt tctctgaaaa tgattcaggc atatctggcc gagatttttt gtttatcttt
     5521 ctttttagag aacgccaaac tactcggtag atggcgagat aacgcggcac tttaagccaa
     5581 atgatcttat ctgcttcttt aatcctttcc tctaatgtag aagtataatt tccttcaaca
     5641 atccatgacg gattagatac cataaacgat tgctgttctt gcaaaaacca cttttttgcc
     5701 tgaatactgt agtctgttgt atgccataaa aggtctagcg gcagtagcgg aaagtcggtg
     5761 atttctttga tcttccttgc gagggtcgat tttcccgacc cactttgtcc aatcacgatg
     5821 atcttcattc ttctccctca cttctctttg gaatttggtt cgatcatacc acttataacg
     5881 ccgcaaaaaa acaagggact gtgacaaaag tcgtgtcaaa gtcccttgtt tcgaataaat
     5941 ggtgttcaat cagctgacct tcagcattaa ctcaaaaaac ggcaaaatat gaggagctat
     6001 tttttcgttt gttcctctaa tactcaggtc aaatcgctga ttttacaacc tcttccttaa
     6061 acggtgttct cctgccaaca cctcggtcac aaggcacaat agtcaacaaa catgagaagt
     6121 tgttttttga aattgctcct tgtgactcgg agttaaacgg caggctcact acctctttct
     6181 taaacggtgt tcaaaagctt gcatctgcgg taataagccc agcaaaacga aaaatatgag
     6241 gggctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct
     6301 gattcacggt gttccagaag tagcttctgc gaaaaacaag ccgaaacttc acaaaaattt
     6361 gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc
     6421 tcttgtaaca agtatttcta ttttaaggct gaaccactgt ttctggttca gtgatttctt
     6481 tgtttttgtc tcgacgagca attgctggca agatcatacc taataagatc aagacaattg
     6541 gtgtgatgat attcgtgaat aattggaacc accatgcttt aggatcagca gtataatcta
     6601 cttttggcac cattcctagg atacatgcaa acgcagtgaa ggcaaagcac caagcaccaa
     6661 agataaaacc gatttttgga tttttaacaa atttatattc agaattgaat ttcttataag
     6721 ctttattcaa catcatatat gccaagaaca cccataggta acgcattggc atgacaactg
     6781 agttcaagtt cgtcaaccat tttactaatt cattcatatc tttgatacca aagatcggca
     6841 acaaaataat gattcctact agtatacctg tcagaagata accattcacc aatgtacctt
     6901 tacgattacg tttacgtagc cagtttggta caaattctgg atccgcatct gctaacaaga
     6961 tttttagtgg tgcatcaatt gaaaaggcta atgcggagat ttgtccaatc atgtttgtca
     7021 atgcgtaaat gatcatcaat gagttaccga taccatagta attacctaaa atttgaaaag
     7081 cactgtatgc cccatttgcc atcaagtctt taggaatatt atcgctagca aacagcatac
     7141 ccattgcgac tgagcctaat acagcacaaa tccctaccat tgctgctaag aagatcatcc
     7201 ctttaggaaa ttcctttgca ggatttcttg tagagttgac ataaggggat attttttccg
     7261 ctcctccaac tgcaaatact agcatcgaaa cggttgtgaa ataactgaaa tcaaatgttg
     7321 gaatatatgt tttcacttga ttcatatgtg gtgtggcaaa ttccatcgtt ggattgatga
     7381 acggtgccgt tacagctaaa agaataaata agatcgacat gacgaacatc gctgttccgg
     7441 ccagtccgcc aatcactttc aaagtagaaa gtccttttgt tgataaatat aaaaaggcaa
     7501 gaaatataat aagtgaaata actgctacca tttgtactga catcgtattt acgatatttc
     7561 catttccttg gactgcccaa ccgccagcaa tcaggattgc ttgaggcttt tgtgccaaat
     7621 aaggaatatg gacgacccag taagtccaag cggcatagta tgccagtcgt ttattagatg
     7681 tcgtattttc gacccatgaa ctgacgcctc ctttactatc cttgaaggct gaccctaatt
     7741 gtccaacgat caatgcgtat ggaataaaat aaatggccaa aatcaatagc caagaggtga
     7801 caactgatac tccttgctga gcatagttat taactacatt ccccatgccc caaaccatgt
     7861 taaatgcaat taacgcaaca gtaaaccagc gtaattgttt gttgttcatt cgttctctcc
     7921 tttatgataa aaatttgtta tccagatgta atcatattca atttttaaca aacttacaag
     7981 acagtgttat tttatgtgtg tattctttta tttaatacac atcgtttttt catatttttt
     8041 ccatcaaaaa aataagttat tttcttttat ttcatttacc ttattgaatt tcaagctatt
     8101 ttgaattttc tgcaaaatta aaaacattag ttattttata atcctatcta ttttctttac
     8161 atttttcatt aagaaaagga tataaaaaaa agaggacgtt cattcgtcct cttcattgat
     8221 caacgtttat tttttacatg caagcttcgc atggcattca aaacagctaa tactgtcacc
     8281 ccaacatctg caaatactgc atctcccatt gatgcaaaac caaaagcacc taaggcaagt
     8341 accaaaattt ttatcccaat agcaaagaca atgttctgtt tgacgatttt caatgttttc
     8401 tttgctaaat ggattgcttc tgcaatcttc gatggttgat cattcatgat gactacatct
     8461 gctgcttcaa ttgcagcatc gcttcccaat ccacccattg cgattcctac atctgctctt
     8521 gctagcaccg gtgcatcgtt gattccatct ccgacaaatg cggtcttttt attgtttctt
     8581 tgtaagattt cctctaaccg ctgcacttta tcttctggaa gcaattcgct atatatcttg
     8641 tccacgccta cttgcttccc gatatgatca gcaatttttt tcgaatcgcc cgtcaacatg
     8701 actgtgttct tcacaccagc cttttttaat tgaaccaatg cgtctacggc atcttctttc
     8761 aaggtatctg caataacaag ataaccactg taactttgat cgatcgctag ataaagcaat
     8821 gtaccgattt cttgacttga aggaaaagag atttcaaatc tttccatcaa tttgtgatta
     8881 cctgctaata cttgtttgcc atcaacttca gctaagatcc cttcacctgc aaattcttgg
     8941 atattagctg ttggtaaaag cggacctgcg tagccttcta aaacagattg agcaatcgga
     9001 tgtgtagaaa actgttctgc actcgcaaca tattgcatga atatctttgg atcgattttt
     9061 gtatcgatcg tctggatcga aaagtcacct ttcgttaatg tgccggtttt atcgaatacc
     9121 actgtctcag tttgtgcaag caactccaag taatttgaac cttttactaa tacaccgatt
     9181 ttacttgctc ctccgatacc gccaaagaaa ctaaggggta cggagatcac taatgcacat
     9241 ggacatgaga tcactaaaaa tgtcaatgct cgatagatcc attcagaaaa cgccgctcca
     9301 gaaacaacaa gtggaggtaa aacagctaat aaaacggcca atcctacaac gactggtgtg
     9361 taatagcgcg cgaatttagt aatgaaattt tcagctggtg cttttttact gctggcattt
     9421 tctactaatt ctaataattt gctgatagta gaattttcat aagatttttc tacttgaact
     9481 aaaaatggtt tatttttatt gataaatcca cttaatactg tttcaccaac atatacagat
     9541 ttagggactg attctcctgt aagtgctgac gtatcgacta atgattctcc ttcgatgatc
     9601 gttccatcta acggtacacg ttcaccaggc ttcacaagta caaactgacc gatctgcacg
     9661 tcttcagggt tcacggtcat caatccttcc gtcgtctgca cgtgagctgt ttctggacgg
     9721 atcgccatca attcgcgaat cgattttctt gaatgactga ctgccaatcc ttggaaatac
     9781 tcgccgattt gataaaatag catcactgct acggcttctg gatattcacc gatcaacata
     9841 gcgccaatcg tagcaacaga cataagaaaa ttctcatcaa agatttttcc tttgacgata
     9901 ttcatcactg ccttcttcac tacatcatat cctatcagca gataaatcaa taaataccct
     9961 atcaagcgaa ttggttcatt aaaatcaaat aatagcaata aagcgatacc tgcaagggaa
    10021 aataaaatcc ggaacagcgt atttctctct ttttcatttc catgttcaga tactttttcc
    10081 ttatctattt ctgttacttt gacatctggt tctaattcct tcactacttt ttttatttct
    10141 tgttcaatcg tagccaaatg atcttcctct gcgtcaatcg ttagttttcc agaagtgaag
    10201 tttaccgttg cttccttgac tccattgatc ttctgaactc ctttttcgat tttcattgca
    10261 cagttcgcac aatctaaacc ttctaatctg taacttttca ttttaatgac ctcctcgcct
    10321 caacatatga atatctcttc ataactaatt ataaatgaac ggttattcat atgtcaaggt
    10381 atccgaaaga aaaaatgaaa aacatctgca tcggaaaatt tcttccatac agatgttttg
    10441 gcttattctt tctttttctt ttcgatcatt gccactgctc ttatccaacc cgcacttgcc
    10501 ttcttgatct tgacaggata gcaactaagt ttgaagcctg ttgctggcaa tttgtctaaa
    10561 ttcattaatt tttcgatagg acaatatctt ttttcaatcc ctgcaaaatg tccttcccag
    10621 atattcgaag ctccactacg ctttcaaaaa tatagaaaga gttctttaat gaaaattatt
    10681 tcaactttcc ataaacagta accccatata aataaaagac gtaaaagtca catggaagaa
    10741 cttatacagg agaacgcata gagtcaggtg aaatacatgt atcccacctg actctatgct
    10801 ttatctaacc tttattattc tcttttatac aatttctgca ccgaatggca tcaacgccaa
    10861 tcgagcaagt ttgaaagatt gcttggcaaa aggtatccct atgatcgtga tacatagaag
    10921 gatgccgctg acgacatgtg cgagagcaat tggtaggcct gaaacgatca gccagatgat
    10981 attaacaatc aatgacatgc cagactggtg ataaattact tctttgccaa aaggcgcaaa
    11041 agaaagggag gcgatcttaa aacattgcat accgattggg atacctatga tcgtgataca
    11101 ccaaagtatc cccgctgcta accagctaag accaccgatt agtccgccga atataaacca
    11161 gatgacattt cctaaacaac tcattgtatt tctccttcta ttactgtttt tgattaaaac
    11221 tgggcaaaaa atgattttat tcttcttttt ttagcttcca gtatcaaata ttctgcaaat
    11281 tttttttgga tttcttccgt attttctttt gttactaatg tgtgttggat tagttttcct
    11341 gatggtcgct gatccaatcg ttcttctgac tgttgcacgt ccgcttgcgc aaatccgata
    11401 atccgttttt cttttgttac agcaacgagc aatagtttat tcttatcatt taggtcagct
    11461 gccgtttttg cttttacgaa tgattctgga tgatcagtaa tcagctgatt gatttgaggt
    11521 agatcttctt ttactgccca ccgtatttcc atcatttctc acttttcttt cgctcatttt
    11581 tatctccact aaaaaaatcg actgcggcaa ttgcatctat ccagctttgt gcaatgatct
    11641 catgtccgcc aatcgttggg tggaccccat cttctcttgt atatttcgaa aaaccataaa
    11701 caatccctaa agcattgaat ataccatcta aaggaaccag caatgcgcca tattccttag
    11761 caagtttacg aacaatttgg attttagggt ctaagtcttt acgccagcca tgacggtcgt
    11821 cggttatagg aagtacaaac ggctccatca agatgatgtt gcagattccc actgtttgaa
    11881 gttcatttag taattttcga taaacggatt caaattgctg agcagatttc tcagttccga
    11941 atatagcctg atcgctagta ttatgccagg tatcattgat tccgatcaaa atcgatacat
    12001 agtcaggttg taaagctaaa caatcttctt gccagcgtac ttgcagatct gcaattttgt
    12061 ctcctcctat cccacggttc atgcattcaa attccatcgt tggatattgg gagattagtt
    12121 ttccggcaat caaaagtgga taacctttac ctagatcagt tgcttctgct cggtctcttc
    12181 ctgcgtctgt aatgctatca ccgataaata atatacgttt tttcatttgt caaaaactcc
    12241 tttttgaata aaacgatgat tttcttcctt atattatccc ataagcccta tcaagacgaa
    12301 agagaaaata tatgtataaa aaatgacacc agcctagtcc cttcaaacaa ttgaatgaac
    12361 gctcatcaag tgtctagttt tttatgctat ttttttctta acgtgccgga ttccccttga
    12421 ttccttcgtt gtttggtcca gagagatcga tcacacctaa gcttccgtca atcagaccac
    12481 tgatgacgcc atcagaacat atatttatag gctcatctaa gacttctagt aaatgtccct
    12541 ttactaatat ctcttctaga ttgcttggga tagattggtc ataactttat ctggtccgat
    12601 gatttcaagg gtgaattgaa cttacatatg gattattgca tgctgaaaat acggacctac
    12661 tccatcttcg aatgttacta ttagtttgtt ttcaggtgct agatgctgct ttatttcaac
    12721 agcagaagca tcatcaaatc agatttccat ttgaattacc ttctttgtaa atgtttgatt
    12781 gattgcgatt tcgttataga accttgtgaa tcaaatagca atttcttttg ctttcttctc
    12841 ttgtctgctg gaaacttcct ttatcccgta ttttaaaaaa agaactgcga gagttcgcag
    12901 ttctttttta gaataaacgg tgctctccgg ccaactcctc ggtcacaagt cacaatagtc
    12961 atcaaacatg aaaaactgtt ttttgaaatt actccttgtg actcggagct gaacggcagg
    13021 cgcacaacct cttgatataa acggtgttca atcagctgac cctcgatatt agctaaaaaa
    13081 acggtaaaat atgagaagct atttttccgt tttgtttctc taatactcag gtcaaggcac
    13141 tgatttcaca acctcttcct taaacggtgt tcaaaagcca gtttctcggt attaagccaa
    13201 atttatgcaa aaatgtggaa agccatttcc acaaaatttt tcttaatact cgaaactaaa
    13261 cagctttttc acaacctctc cactaaacgg tattcaaaag cttacatctg cggtaataag
    13321 tcccgccaat tcaaaaacat gaacagctgt ttttgcttgg ctgttctaat tacttgatgc
    13381 agaacagctt tttcatcacc tcttatggat aaattcggtt caacaaacgt gggaatggaa
    13441 tagcttcacg cacatggtcg ataccagcaa tccaagtgac tgttcgttca aggcctagac
    13501 caaaaccaga gtgcggaaca gaaccgtatt tacgtagatc aagataccat gaatattctt
    13561 tttcatccaa accgtgatta cggatttgtt ctagcaagaa atcatagtcc gttgcccgtt
    13621 cgcttccgcc aataatttca ccgtaacctt ctggtgcgat catatctgca caaattacca
    13681 cgtcttctct tgttggatgt ggtttcatgt agaatggctt gatagctttt ggatagttta
    13741 ggataaagac aggctgttcg aatgaattcg caatgaacgt ttcatgaggt gaaccaaagt
    13801 cttcgcccca ttcgatgtca tcaaatccat ttttcttcag taattcgatc gcatcatcat
    13861 aagtaatacg agggaatggc aattttgtat aagtttttaa gacttctttg tctcgtccta
    13921 gtacatctaa tgcgtattcg caatgatcta aaacattttg tactaagaat gctacatatt
    13981 gttcctgtac ttctaaactt tcttcttgat gagtgaaagc catttctggt tcgatcatcc
    14041 agaattcaat caaatgacgt cgtgtttttg atttttcagc acggaaagtc ggaccgaatg
    14101 aaaagacttt tccgaaagcc atagcagcag cttccatgta taattggcca ctttgagata
    14161 aataagcttt ttgatcaaag taatttgttt cgaatagatc cgtagtgcct tctggtgcgg
    14221 aaccagtcaa gatcggcgga tcgattttga caaaatgatg ttgattaaag aattcatacg
    14281 ttgcacgaat gatttcattt ctgatctgca taatcgcatg ttgtcttgaa gaacgtagcc
    14341 ataaatgacg atgatccatc aagaagtctg ttccgtgttc ttttggtgtg atcggataat
    14401 cgtggctctc gcttaccact tccacatttg taattccgat ttcataacca aattttgaac
    14461 ggctgtcttc acggatttct ccagttacta acacggatgt ttcttggtgc agatttttag
    14521 ctgtttggaa aacttcttcc ggcacttcgc tttttacaac tacaccttgg aaaaaggctg
    14581 ttccgtctct taattgtaaa aatgcgattt ttccgcttga tcgcttattt gcgacccaag
    14641 cgccgattgt tactgtttct cccacatggt ttttcgaatc gatgatttga atttgttcca
    14701 cgtatgactc tccttttata ttccttgaat ttcttcagga ttaattttga cttttactct
    14761 caataaattg cttgattctg cgtaccgctt cttctaacgt agcgcgatca gtggcataac
    14821 tcatgcggac attttctggt gccccaaagc cttcgccagt cacaagcgct acccctgttt
    14881 cttctaaaag atcttctacc cattgtgtga cattttcata tttacacatg cgtagcgttt
    14941 cttttacatt aggaaaaaga taaaaagctc cttgtggctt ttcaagagaa acacccggca
    15001 gttctgccac aagcggatat aacgtattca ggcgttcttc aaaggcgttc cgcatttctt
    15061 ccactgtatc ttgctcgcct ttcaatgctt caacagctgc atattgactg actgctgtcg
    15121 gattgctagt tgattgggaa gcaacagcga tcattccatt gatgatcaca ggatttccca
    15181 ccgcataacc aatgcgccag cctgtcatcg catatgtttt agacacgccg ttgatgatga
    15241 tggtctgatt tttgattgct tctgaaatcg ttgcaattgg agtaaactca ttgccattat
    15301 aaactaaacg gccataaata tcatcagcaa ctatcaaaat atcatttttt actgcccatt
    15361 caccgattgc ctgcagttca ttcttgctat aaatcattcc agtcggattc gatggagaat
    15421 tgatgattac ggcttttgtt ttttctgaac gtgcttgttc tagctgctca acagtaactt
    15481 tccagctatt ggattcttct cctttcaaaa agacaggaag tccttctgcc agttttactt
    15541 gctcaccgta actgacccag taaggcacag gaatgatgac ttcatcttgc gggtcaagga
    15601 tcgtttggaa aagggtatac aaagcaaatt tcgctccgtc tgttacgact gtttgtgaag
    15661 gttcatagac aagtccatag tttttcttca gataatcaac gattgcctgt cgaagctctg
    15721 ggattcctgc tgttggtgta taatagctag ctttcccatt gcggattgct tcgattgctg
    15781 cttcttggat gttttctggt gtcgcaaaat ccggttctcc cacagtcaaa ctcagcacat
    15841 ctctgccttt ggcttttaat gccttggcct ttgccgcagc tgccaaagtg acagacggtt
    15901 ctaatcgttt tgttcttttt gataactcca tcccattcat tcctttacct tttaaattcc
    15961 cttgattgtc ttgacttcat ctccagattc aaagccaatc aggtaataat tcagtttccc
    16021 atttgtttct tttcctacta cttcccacac aggctgatca tcatacatcc ctaaagcagc
    16081 tttttcgatt tggatttcag gatgggccgc agcaattgtc tgttttgctt cattttcagt
    16141 cagtcccttt gtttgatcca atacttttac tttttcacca gatttaggaa tgataacggc
    16201 gatttctttt cctttatcat ttgtacctgt cagtgaaaag tatgtcttct ttcgagtaaa
    16261 ccaataaaaa tgatcggctt cctcaagatt tgcatatttc tttgcgattt ctactgcttc
    16321 tttcttcgcc tgcaccgccg gacgactgga acgcaagtaa aaaatcgagc tgatcacgat
    16381 gaccgctaat aaaaatacga tcaagccaag taacacgcga ttaatcgttt tttcctttgt
    16441 ctgttttttc ttcaagggtc gtcgctcctt tatcttcatt ccttttcatt atagcagatt
    16501 ttaattatga aaaaagacag ctcctctaac ttccttcttc atttttcttt aagaattcat
    16561 ggatatcctg atagatttcc tccatagcta gctctttgat cggtactttt ttcggtaatg
    16621 catggatgat ccgtgcacca tattttgcag taactagtct tcgatccaaa ataagcaata
    16681 cgccacgatc tgtctccgtc cttatcaagc gtcctaatgc ttggcgtaac ttcaaagctg
    16741 ctttaggtac ggattcctgg taaaaaggat tgatcccctc tgattctaaa taagcgttcc
    16801 tagctttgac catcgggcga agcggattat cgaagggtaa acgtgtgact acaacgatct
    16861 gcaaagcatc tccaggcaaa tctacacctt cccaaaaact gtcagcgcca aacaatacgc
    16921 ttttttctga caaaatgaag cgtttcaaaa gcttctcccg gcttccgcca aacccttgag
    16981 ctagtatttc tcgtcctttt tctagcatag acagatgcat tttctgatag accttctgca
    17041 aaacatcatg agaagtgaat aacacaagta ttggccgatc ttcttgttcg atcagacctg
    17101 taagtgctgt ctctaaataa tcgatatatg cttgattgct gacttgatgg acggcaggtg
    17161 cctcttttgg cacatagatc cttgcctgtt tctcataatc ataaggagag gcaatcactt
    17221 taagaggtgc tgcttcaatg ccaagccgct tagagagata gtgtcgatta gggccgatct
    17281 tcagcgttcc tccaatataa agaatacgat catatcgagg ataccaaaca gtcgacggca
    17341 acatagccgc ttgaaaatca tggagatgaa aaatcatctg ctgcgctgtg ttcccaggaa
    17401 cgaaccaatg gatcaaatga tctcgccagt cttccagcca ttgatccatc agcaagtact
    17461 gcttgtctaa ttgatcaaat aagctatata aacttgctaa atcgatccgc atctggtttg
    17521 tccagctttc ttggataatc tcaaaagtca gacgcatttg tgactgtagc tgctggatct
    17581 cctgataaaa aagctgcagg tgatcaatgg ctgtcccaga ttccagtggc agctgatcca
    17641 acatctcttt tgtcgtcatg acttcttctg gatactgtcc gttaggttgc ttgccgctca
    17701 ctaaactcat taatccttct gccatacaaa tctgtgcttc gcatagcgca gaaagttctt
    17761 ctcgataaat cgataaccag cgtaaggctt catgttcttt cggtaaatag ctttgtattc
    17821 ggtcaaacag ctgatttggt tcttctaatt gctggatttg tttatggaaa tagttaatac
    17881 ttaatcgttt gtcatttact ttttcagcga tttccggcaa atgatgtact tcatcgatca
    17941 acaaaaatgg actagctgga agcaatggtt cttttcgctg tgtttcttgt attaaaaacg
    18001 catgattgac aatcaaaaaa ttactttgcc tgattttctt ttgcaagaaa cgaacaaagt
    18061 cttgttcgta aaatgactga tttcttgcta aaaatccagt gcctctgtgc gcgatatctg
    18121 caaagaatga atggttcaaa tttgttaaat gtaattcatc caaatcaccg gtcttcgttt
    18181 gcgtcagcca aactaagacc gccatttgat acaaagcata ttgtttttgt tctggcggtt
    18241 ccacaagtgt gcctttaaaa cgctgtaaat caatatagtg gcgatagctt ttgataatta
    18301 caggttgtat gggctgatct agcaattgat tcagcaatgg aatgtctttt tctatgatct
    18361 gctgctgcaa aactagcgaa acggtactga tgacagcggg tttttcaggt gtagccaaat
    18421 aactcaatgg cagcagataa ccgattgttt tacccattcc tgtagctgct tcgatcatca
    18481 aatcttttga ttcatctttt gtgaaatggt cgtagaccgc attcatcagt ctgttctgtt
    18541 cttttcgata catcagtgtt ttaccaaaca ttttttcttt tgcttgtttt tttcttggat
    18601 atgtccgctc gccataatgg acgtatatga atagttccac ttcttttttc tgcaaagcta
    18661 gcccatcgac gatttctaat gagggatcaa gtggctctgg tttttctttc atttcttcaa
    18721 tcacatgata aatgaaacga ctcgtatcca tacctgtgtg tctacttaat cgcgcaatct
    18781 gctctaacgt gatgattggc aattttctca tccgttcttc gatcagcaaa agaagttgac
    18841 ccgtcacttc ggcatcacta tctgcctgat gaggattctc atgaataaat ccaaggcttt
    18901 ctgacaaatc agctaagcga aagcttggtt ccgtcggcaa gaaaatttgt gcaagttcta
    18961 ctgtatcgat gcctggtatc ttcaaactag gaagtccgca tcgcatgagt tcatggttca
    19021 aaaaattata atcaaaataa atattatgcg cgacaaatat ggtgtctgcc aaaagattgt
    19081 aaatcgtttg ggcgacatct tcgaaataag gcgctttttg gacgcgttga ttcgtgatcc
    19141 ctgttaaatg ctggatttgt tttgaaatct tccgccctgg atgaatatcg atcgaaaaac
    19201 gtgaagtgat ccgacctgat tcaatcatga cgcagccaaa ttggatgatc cgatcttctt
    19261 ttggattcgt cccagtcgtt tcgatatcaa cgactgcata agttcttggt ttcaaaatat
    19321 cttcctcttc tcctgcctct aatgttcttt tgaaattata ctacaaagtg cagaaaaata
    19381 ctctcatcgc tttttaaaga aaatagacaa aaacgcccag acacgcaaat gtctgggcgt
    19441 ttatttttta gtataggtta attaagcttt agtaacgttt gttgcttgag gtccgcgttg
    19501 gccttcttca acatcgaaag ttactgcttg gccttcttct aaagttttga atccgtcgcc
    19561 ttggatagct gagaaatgaa cgaatacatc gtttccgttt tctgcagtga tgaatccaaa
    19621 tcctttttct gagttaaacc attttactgt acctgtttcc ataataaaaa tcctccttgt
    19681 gtatcaacac atattttgca attacttgaa tggtgtatat ctggaagatg tttatttgaa
    19741 acaagctacc acagattacc gaacaaaaac tactcctata gtatatcata ccgtttacaa
    19801 aaaagctaga gtttttcgac tttttttatt aaaaaaagtt ttctcagcga ttacataaag
    19861 tgaaaaaccg aacttttttt aaaataaacg acatattgtt cagttggtgt ttttttgctc
    19921 tgatgttctt ctttaaacta aaaaaattat tctttctgac tacttatcgg ttctgtttca
    19981 acggtcgagg ctggggaaga ttctttagta ggtctgatgt tctcatggta tttctgatag
    20041 cctatgacag ttaccagaag aacaaggcaa accaatacga tcaacgagat tagtttttct
    20101 tttttgctca tatctatacc tcataaataa caggatgatg tccatcatat ttctgagtat
    20161 gagtaaaagc aaaagctgca gctgtagaat gtaagaaatg ccagcaactt tcataatcac
    20221 aggtcggaca gtaccaaaag taaccaaatc ttggctgcaa agaccgttct tctgtttcag
    20281 gaatcgcaga atcaagatct gttgtctgta cataaacatt tttgtacaga cgtgtgcctg
    20341 taataggaga ccgctgtgtt tcttcagcaa aaactggctg acttgttaaa cttagggata
    20401 gaaacagcaa acaccataac agtctttttt tcataaagac ctccttatcg ataagttttt
    20461 cccaattaaa atcatatctc aagaacgccc gttattcaca ttttgttcat aaatgatgtt
    20521 ttttgtatca taatcgtcaa aaagaggtcg tgaccacgtc acaacctctt ttttaaacgg
    20581 tgttccagaa gtagcttctt cggaaataag tcgaaatttc acaaaaattt gagaaataat
    20641 ttttgtcaat ctcttcttat ttcttgaagc tgaccacttc tgtcacaacc tcttccttaa
    20701 acggtgttca aaagcttgca tctgcggtat tagctcaaaa aacggaaaaa tatgtgaaac
    20761 tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca acctctttta
    20821 ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat ccaaaataaa
    20881 cactttcccg ccattaatga tcacatcatc tgctaatgca ttcaacactt gacgccgatc
    20941 atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag cgataaataa
    21001 atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat cgatgaattt
    21061 cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac ttgacagctt
    21121 cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag aaatcgcaac
    21181 gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat tttctggtaa
    21241 tgcaaataaa taaatcggcc attgttcagg attttcgaaa gaatccttca agtacgtatc
    21301 aacagcttgg taatagttga cccaatcgat ctctacttct tcatcttttg gatttacgcc
    21361 atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt tcaaaccgcc
    21421 acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt ctggtagaga
    21481 tacttctttt acttgtttgt tgctgacctc atacaatttc atggagtcgc ggttcaatcc
    21541 caataaataa taagaatagt tgaactgccc atttttgata atagccagta aataaggaag
    21601 atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat aggtctggtc
    21661 agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag gatctcctaa
    21721 caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt ttttctcaaa
    21781 acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt ccacatcttg
    21841 atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc cttctgaagt
    21901 caattgtgtc aataattctt tatccttttt tgccataaac gtacccctcc taaaaaaatc
    21961 attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa taaaacgtat
    22021 ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa gttatcttca
    22081 taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg ctgataaact
    22141 aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca gtttattaag
    22201 tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa cacagcctat
    22261 tcctgtaaaa gtacgtaaaa acgaccgcta aacttccata acgcgcgttc ttatcctaaa
    22321 gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat ttgtagcgaa
    22381 acaaattaat tacaaggaga tcggatatgt ccataaaaaa aaacacgtct agtcctatta
    22441 ttggctagtc tcattctttg ccttgcttct tttctaccag ctgttgctgt gcaagctgaa
    22501 gatacgttca aagtaaatgc aaaagcagct tttgctgtag atgcgcaaag cggtaagatt
    22561 ctttatgatc aagatggaga aaaaaccatg gggatcgctt caatcacaaa aatcatcggt
    22621 ctttacatcg tccttgatca agtaaaagaa ggaaaactgt catgggatga taaagtttcg
    22681 atttcagatt atgcagaaaa tttgagtatc accccagatt tatcgaatgt tcctttgcat
    22741 aaagaaaaca cctacactgt caaagaatta ttcgactctg caatcatcca gtcagccaat
    22801 gcttcaatgg tggccttggc agaaaaaatc tctggcagcg aagctaaatt cactgaacga
    22861 atgaaagaac aattgaaaga ttggggaatc aaagatgcaa caatcgttaa tgcatcagga
    22921 ttgaacaact cttatcttgg cgaaaaccga ccagaaggca ctggagaaaa cgacgaaaat
    22981 caaatgtctg ctcaagatgt ggccatcgtt gcccgccatt tgatcttgga tttcccagaa
    23041 atactggatg tatcaagtac tacgacccaa atgtttggcg aaaatacgca atcaccagtg
    23101 gaaatggtca actggaactg gatgctccca ggattcgtta attacaagga aggcgtggac
    23161 ggattaaaaa ctggtacgac tgagcttgca ggtgcttgtt tcgttggtac gatcactaaa
    23221 aacgatcaac ggatcatcac tgtcgtattg aatgcggacg gccatgcgga aaacccgagt
    23281 gcccgcttca atgaaacaga ccgtttgatg gactactgct atgacaattg gtcagaaaaa
    23341 gagctaggaa aagctaacgc aagtattcct agtctaaaaa ccattgatgt aaaagacgga
    23401 aaagaatcaa cagttcctgt tgtgcttaaa agccctgtaa aagtatgggt acgaaacgat
    23461 atggatactg gcaaattaac gatcacgcca acacttgaca agaagcaagt cactgacaat
    23521 gagatccaag cacctatgga taaaggtaca aaaatcggta ccgctacgat caccttggca
    23581 gacgataaat taggctattt agaagacaac aatgcacctt caacagagat cattacggat
    23641 aaaacagtgg aaaaagcgaa tatattcgtg attggctggc gacgcgtcgc agaatttttc
    23701 ggcaacttgt tttaattgaa caataagaaa aacatctttc catcggaaag atgttttttt
    23761 gctttttcta gtttaaataa cagctttttt catctatttt cgttatactg tataagaaaa
    23821 aggagttgaa tttatgaatc taaccagaga tctgatcttt ttagttctct atcttattgg
    23881 ggtattctct atcgtttatt ggcgaaaaca gaagaaggat ccttccttgt tcttttacgg
    23941 cagtacgtgg acatttacgg taatcttaac ttattttgtc gtgttggaaa ttttttattc
    24001 gaccttttat tttttgattc cattgttgtt ctttagtatc tttgcttttt cttatttcac
    24061 agaaaaacga aggctgctga atggtctttt attcaatgtt ttcctcatca gtttcggcat
    24121 ctacttgttt gtcttgctgt atgaaacgca aaatattttc cttggcggac tgatcgcctt
    24181 gatcacgatt ccattgctac ttgtcctttt atttggtatt tatggattga ttgtttttct
    24241 tttttggaac ggggtcacag ttttacgtag agaatcgcat tcattagcta atcttttaac
    24301 gttgatacta gccatttttc ttacactgtt tcttgttttt gactttttct tgttaaaata
    24361 tttgccgcaa tggataaatg ctttgttttt ctgcgttccc ctgatcttga tctatctatt
    24421 tatcgtattc tacaactttt tgactgtctc attcttgtat cagttcaacc ggcctcgata
    24481 caatcaagac ttcatcgttg tgttaggcgc tgggttgatc aatggagaaa cagtttctcc
    24541 tcttctagcc aagcgaatca ataaggcaat tgctttttat cgggctcaaa gccgtgctac
    24601 attaaatccg cccatcttat tgatgtctgg cgggcaagga gcagacgaaa aagtaccaga
    24661 ggccattgcg atgaaacaat atgccatgga acaaggaatc cctgaaagag acattcttgt
    24721 cgaaaccaat tcgacaacca ctttggagaa catgctctat tcaaaggaaa tcatggatca
    24781 gcaaatgaaa gggccatacc gcgcgatctt tagttccaac aattaccaca tttttagagc
    24841 cggtctttat gcgtggcaag ccaaattgaa agcaaatggt attggtgcaa aaacagcttt
    24901 ctactacttg cctaatgcgt ttttaagaga atacatcgcc atcttgatga tgaacaaaaa
    24961 aagacatatg atcatttgcg gattgctttt cgcaggctcc gcattcttat cgctgattac
    25021 tttacttttc taaaaaaaca aggtgtgaca aaacatatgt cacaccttgt ttttttcttt
    25081 cattctctta actattggca aaaagagtat cccttttttg accgctactt gctgagcaga
    25141 ataaataccg ctgttgcctg aacacataaa gctgatcaag cagatcataa agaagtatac
    25201 tgccgcttgt gaaccgaaca attcgatccc catcacaaag caggcaatcg gtgtatttgt
    25261 cgcaccagaa aatactccga taaagcccaa tcctgcaaga aaaggaacag aaacatggag
    25321 caaaggcgct agtgctgcac caagcgttgc accaatttca aacaatggtg tcacttctcc
    25381 cccttgatat cccgcgccta aagacaaaac tgtgaagaat aacttcccaa taaaatcata
    25441 gacatgtgcc tgtccattaa atgattcttg aagtaacgga agactcaatc cgagataacg
    25501 ttgtgtttgc aaaatcaatg ctgctgccac aactacagct ccacctatcg tatttcgcca
    25561 aacaggatga ggaatccatt gtgcatatcg cgcttttaaa aagacgatcg aacggctgaa
    25621 tacccaacca atcaaaccaa aagcaatccc agcaacaaaa actttgaaga acagcaacat
    25681 actccattca ggaatcacac ccatttggta atgtagatga gaaacaccat agctttctgt
    25741 catgaaattt gcaaacagtg cagcaaagaa gctagggaag atcgcttctg ttcggacttt
    25801 cccgattgcc aacacttcta atccaaataa tgttccagct aaaggtgtgc caaatacaga
    25861 actaaaaccc gcactgattc cactgataat caagatttcc cgttctgatt tatccaatcg
    25921 gaacaaacgt gctgtattat ctgctaacgc tccccccatt tggactgctg ttccttcacg
    25981 gccaacagat cccccaaata aatgggtagt tatggttcca aacagtgtaa gtggaataag
    26041 tcgcaacggg attttttctt ctccaccatt tccttgatcg atcactaagt tgtttccacg
    26101 actagaaaga ccgccgtgat acgcatagag ataagcaaaa agcgcaccac taactggtag
    26161 tagataaagg agccaaggat gtgatagtcg gatatctgtc acaactgtca ggctatttaa
    26221 gaaaaaagca gacaagctcc ccatgaatat accgagaatc gctgtgatca ccagccactt
    26281 cagcatgtac actaaaatgc gtactggact cggtaattgt ttttccataa aaaattcctc
    26341 ctcaataaaa aaacgcctac taaagaaagg ggctgtcccc agactttagt aggcgtcatt
    26401 agctatcttt cgttagcatt taaaggcgaa caccatcacc tattcacttc cattaaaaga
    26461 tagcatattt ttctgtaaaa aacaataaaa ttatcgttct ttctttacac gttcagcaaa
    26521 ttcatagaaa ggagccaatt tcgttaactg ttgattacat tggtcactat catgacaaat
    26581 ataattcccc tttttcgtat acgtgccatc agaacctgct ttcgttgtag aaagaaaaag
    26641 cgaaacattc gatgttttct gacagattgc acagattccc ttatttatcg ttggtgataa
    26701 agtaccacta atccctttta atttttcatc ttcgtaatag atcatgaatt ttttctgcgt
    26761 acctggatca ttccagccga tgtacgtatg ttcttgcaag tcgatttcat tccaagctgg
    26821 ttgtttgagt tttttcactt ttcggaataa tttctcgatt tgtggtttgc taggctgcat
    26881 aaacggctga acgatttgct tcagctcctc caatgctcgt tctgcttgcg cttttgtcag
    26941 ttttacgtct aaaactgtcg ttaaaaatgt atcgatttct ggcagttcgt gttctaatat
    27001 gtctcgaatc ttttcagttg ctagtgcctg aactgtttgt accgtttttg gatcattgac
    27061 agatgagtac gcatttaata actgttctac ttctcttttt ataaaaaaat attggtatgg
    27121 ttttattgtt tgttccatga ttttaaagtc ctttcttcta accaaagtgc atactttgta
    27181 gaaaaaagtg atcttctgca aagtatgtgt tacctgaaga tcccggactc ttttaaataa
    27241 gatacgtttt gcatcttatc atcaccccct ttaatgctta ttcttctatg tacatgattc
    27301 attcgataaa taaaagtaaa ccgtatcttg aacagatagt caactgcaaa cagaaaaaag
    27361 gactgtgaca aaagtcgtgt caaagtccct tgtttcgaat gaatggtgtt caaaagcttg
    27421 catctgcggt aataagccga aacttcacaa aaatttgaga agtaattttc gtaaattcct
    27481 tcttatttct tgaagctgac cacttctgtc acaacctcaa tatggtctat tattggtttt
    27541 acctgttaaa tcgaggattc tttcccaaag taacgttgcc atctcttacg catacttgca
    27601 gacatgggct gagccgcttc tttgactgcg cagtatttgt ccacgaatgt cacaatatat
    27661 ccttctttat acttaggcgg tgcgatcgtt gcaccccaca tgtgcttcaa aatgatatct
    27721 cgctcaagat ccgacaaatc ggtgattttt tctgcattct ttacagcaat tcttggatgg
    27781 atatacgcat gtgtcccctc gtcaaatttc gtcgtacgcc aatcatagta gaacagatca
    27841 tgcaaaagtc cagcacgcgc tgttgcttta gcattgccac cccatttttt tgcgagcaga
    27901 taactatagt aagaaacact gatggaatgc tccaaacgag tggaatgaac atgctgtgtg
    27961 taattcgcta attttttcac tgcttctgtt tctaaaagat cttgtacata agacatatat
    28021 tcttcgtctt cacgccattt ttctgtcata attatcgatc tgccaccttt ttgaatttca
    28081 ttttcttctg aaattgatct aagtatacca ccagtgttcg gattattcta gtcgctctag
    28141 ataaaatagc taaagcttaa tagttcctta atcataaaga aaaatgataa agaacgatcc
    28201 ctgctgcgac tccgacattc aatgattccg catttccttt cattgggata tatacgttct
    28261 gatcagtcaa agacaagatt tcctgactta ctccctgacc ttcgtttccc atgattatag
    28321 cgaaatcctc tgttttttct actttgtcta atgcatgtgc ttcttcattt aattctgtac
    28381 cgtacaccgt aaaccctttg cctttcatta cagggatcac ttctgccaaa tctttttgta
    28441 acacaggcaa atgataattg cttccctgca tgcttcgcag cacctttgta ctataaatat
    28501 ctgccgttcc tttacctaat aaaacaccag ccataccaaa cgcatctgcc gtacggatca
    28561 tcgttcccac atttccagga tcctgtacat tatctagtaa aagccagcct cctgaaaaat
    28621 ctggcgtatc ttcagatgtt aacgtcatca ccgctaagat cccttgcggt gtaggtagat
    28681 ctgacatagc ggtcatgacc tcatctgaaa ctagaaaagt agaaatctct ttgtttacag
    28741 ccagccagtc tccccattct ttcatacctc tctgtgtcac aaaaagttct tttatttctg
    28801 catcagacga cgcagcttct tcgatcagat ggaacccttc caaaagatat tctgcctttt
    28861 cttctctgta tttcttttta tgtagctttt ttaattcttt gatttttgga ttttttgctg
    28921 attggatctc tttcacattc cttcacctca cctgattata tcatggaata ggtgcttgag
    28981 cttgtttcat cctaaaaaaa tcggtatcat tgatttataa aacaggaaag aaaggtgacg
    29041 aacatgcgca aagttaaaat gaatgtccaa ggacgtgtcc agggcgtggg atttcgctat
    29101 atgaccaaga tggttgctga tcagttaggc gtgaccggaa cggtaaaaaa cgaagacgac
    29161 ggctcagtca caatcgaagc aatcggaaat gacgacatca tccaaaaatt tatcgaagaa
    29221 gtcaagaagt ctccgagccc aagtggacga gtgcagtatg tggatgtcca agaagatccg
    29281 atgattgagg aacgaaagaa atttgatgtg gtgggataag gttgtgaaaa ggtcgcttag
    29341 ttttgagtat taaggaaaat tttgtgaaaa tggctttcca catttttgca taaatttgac
    29401 ttaataccga gaaactgact tttgaacacc gtcgatcagg ttgtttttga ggcgctttgc
    29461 ctcaagtatt aaagataggt agtaaaaaag ctgatctata acttgcaata aatttgctta
    29521 acccatattt tccagacaga acaaaaaagt ttttagtttt ttatataaga aagaaacact
    29581 tggaatcact cttttctttc caagtatttc tttcttgatt ttttgtcttt tttcaaaatt
    29641 tttcgctacg aaaaagaaag aatatttata tgaaatttct atgaagttga ttgaattcca
    29701 tgcgcttttt tagtatagtt aagtttgtgt aaaaattata gaagaggaag tattctatga
    29761 ataaatggaa aaactggtta ttgggatccg gacttgtcag tatcctgctc tttttatctg
    29821 gctgtgtgcg gatggattca aacggaaacc ctgacacttc aggaatcgtt tatcgagtac
    29881 tcgtccatcc tatgggccaa gcgattacat atctagttga gaatttcaat tggtcttacg
    29941 gctgggcagt tattgcaatg actgtgatcg ttcgtatcat catcttgcca ctaggtatca
    30001 gtcaatcgaa aaaaacaatg atccaatctg aaaaaatgca agcgttaaaa ccacaagttg
    30061 aagcagcaca acaaaagcta aaagctgcaa caacacgtga agaacaaatg gcagcacaag
    30121 cagaaatgca gcaagtatat cgcgaaaacg gattgagtat gaccggcgga atcggctgtc
    30181 tgcctctatt gatccaaatg ccgatcttct ctgccttgta ttttacggct cgctacacag
    30241 aaggtatccg tgaatcatct ttttacggca tcgatctagg ctcaccaagt atggtgcttg
    30301 tggccattgc aggggtcgct tatctgcttc aaggatatat ttcaacaatc ggtattcctg
    30361 aagaacagaa aaagacgatg cgtacgatgc tgatcgtctc tcctgctatg atcgtcttca
    30421 tgtcgatcag tgcgccagcc ggcgttacac tttactgggt agtcggtggt gtgttcagct
    30481 gtctgcaaac attcatcaca aacgttatga tgaaaccacg cttgaaagca caagtggcag
    30541 aagagttgaa acaaaacccg ccaaaacaag tcgtcactcc aagaaaagac gtgacagaat
    30601 cagcaaaacc agctgacaac aaacaagcaa caaaacaaat caaacaacca aaaaacagta
    30661 caaataacaa aggccgcaac gcaggaaagc agcagaagcg gaagtagata gtaaataaga
    30721 gtgtaataaa aattcattaa cagttttagc aattaaaaat atcgaccaag atttttgaaa
    30781 aagaaatcta gtcgatattt ttatttaagt gaatgtataa tttgaatcat cgattgatcg
    30841 ctatctaatt gcagcagcat ctttttatga agaaacaact ttttcttatc tatcaacgta
    30901 gacaggtgtt gctgtttctt ttaatagtgt acttaattcc ttaatatttt gttttccttc
    30961 ttctaacatc caactactcg ctttttcttc gccttcggta acaaaaggtg ccactccctt
    31021 cgcccatgtt gctcgcccac ataagacacc attgaatgtc gaacctgatt gttttgcaaa
    31081 acgtaatgta tcttgaaata acgtagcatt gactcccgca cttaaaaaaa taaacggttg
    31141 ttcagtcact ttcgattgtt catagaaata cgcggatgcc tctgcttgac tataacaagt
    31201 ctcttgccca tatccttcca caaatctcat attcactggc acttctactt tcaatacatc
    31261 cacttgataa cgttcttttg aaaattctcg catggcttca ataactttat ggggttttac
    31321 ttttgcatag gcaagagagg acggatcgcc aatagttgca tcataagaaa ggatctctaa
    31381 aaagaaaggt atgccttctg catcgcattc tgaaccaatc cgttctataa ctatttgttt
    31441 ttgcacatta atctctgctg gttcatccac gtcatagtac aataaaaatt tacaagcatc
    31501 cgcaccagct tcttttaacc ttttcaccga ccaaatattc aataaatcag gtaatcttcc
    31561 cggcattttc gtatcatagc cggttttttc ataagctagc agcaagccac attctttctc
    31621 tctaagcgct gctgcaggca ggccgcattc tggatcaagt aaaatagctg aggcataggg
    31681 agtcaggtat tgagaaacca tctgtttaaa ttggatgatg tcttctgatg tagcttcttt
    31741 atattggttg atcattttct tcaaagcacc acgctggtcg attgctaacg cgctaataat
    31801 tccagcttca tccgtcaatc gcttcaaacg ttcctgcttt tctatactca tcttcttcat
    31861 agatcttcac ctatttcttt agttaatatt gtggctattt ctgtttttga ttttgctttt
    31921 ctcaactgtt ctgtaacctc ttttcgcatc aatgatcgtg caacgagaga caataatttc
    31981 aaatgagtcg ttcctgcttc tgaatctgga ataaataacg caaaaataaa atcaactgac
    32041 tgtctatcta aactgttcca ttcaattcct ttgttcagtg tgacgataat catactaggt
    32101 tcgttgattg tttgagactt cgcatgaggg atagcaaaac ctgacattat tcctgtagta
    32161 ccttcttttt ctctttctag aagttttcga tatacttctt tttcgtcatg agcgattcct
    32221 aaacagaatg tttgctttgc taaaaactta aatgcttctt cttgactatc taatggctgt
    32281 tgtaaaaaaa tgttctcttc atgaatgatt gtcatgataa gcctcctgct cttccttctt
    32341 cgataactgt acgatttgct gctttattat ccatcttctt gtctttatca gttactcttt
    32401 tcttttggat caaacctagt atcactccac caacgatcga accaataaga atcgctgtaa
    32461 cccattggat ttttcccgtc actacaggta acactaaaaa accgccatgt ggggctggta
    32521 cttggacacc aaacagatag gtcaagacag cagcaattga tgagcctaac atcatcgttg
    32581 gtaatactcg gatcgggtct ttcgcagcaa acggaatagc tccctccgta atatgagttg
    32641 atcctaaaat aaaattaacc aaacctgcat tacgatcatt agtatcaaaa tatttaccaa
    32701 acaataaagt tgcaaaacca gtaatcaacg gtggtgcaat gcaagctact gacacgccag
    32761 ccataaaagt cgtgtttcct tgtgccaaaa gagctgtacc tgttacatat gccgccttat
    32821 taatcggtcc tcccatatca aacgcacaca tgcaaccaac aatcacgcca agaacaagtg
    32881 gattcgaatg ttcaaatcca gctaaaaagc tcatcattcc ttcatttata gccttcattg
    32941 gacccgccag caaagacatc acgatgccga taaacactac accaataact ggatataaga
    33001 agattgcctt caagccatct agttgtttag gtaaaattgt cagtagcttt tgcaaaaata
    33061 agataaaata acctgctaag aacccagcta aaatacctac taaaaatcca gtaccgccac
    33121 tcatggccac gattccacca acaaatccaa cgactaaccc tggacgtttc gcgatccctt
    33181 ctgcaatata agctgctaaa actggaacca tcatccccat tgctgcatcg ccaaccgttt
    33241 ttaacatcgc cgctgtagca ttgtattgtg catggtctgg atcaaaagaa tagattcccc
    33301 aaacggcaaa tgaaatagca atcaatactc cgccagctac cacgaaaggc aacatatgag
    33361 agacgccatt cattaaattt ttatagatgc tgcgaccaaa attagcacca cttatcgttt
    33421 ctgattctaa agtatcaaca gcttcattat ctgctaagat ggtccctttt cctgccaatg
    33481 cttcgtcaat cagccgttgt gcatccttga ttcctgtact gacagaaaca tcaatgactc
    33541 gttttcccgc aaatctttct gaatggacat ctttgtctgc ggcaataatg acagcatctg
    33601 cctgtttgat ttcttcagcc gttaattcat tctcgatccc aatttgtcca tgggtctcca
    33661 ctttgatcgt gatgcctttt tttctagctg cttgctctaa tgcctcttgc gccatgtagg
    33721 tgtgtgcaat tcctgtcgga caaccggttg ctgcaattag ttgatatttt cccatctttc
    33781 gaacctctct tccttgattt tgatttgttt acttaattcc tccacatcca aaaaatcagt
    33841 cagtccttta cgaaaagcag tagagctgcc tgctgctatg cttttacgta acgtttcatc
    33901 aagcggtcgt cgattcatgt atcctactaa aaaagtgcct aacatggcat cacctgcaca
    33961 tgctgtattg acaacttttc cttttggcga gtttcctcga atcaccctgt ctttcgtaaa
    34021 aagaatcgct cctttctcac caagggataa caaaacattt tctgcacctg actctaccag
    34081 tcgttgtcca taaacaaagt aatcttcatc tgtaaccatt tttcgtccga accaagaaga
    34141 aagttcttcc tcattcggtt tcagcaaaaa tggtcgatag ggcaaacaat ccatgacctc
    34201 ttgatcactg ctatcaataa tcaaatgaat ctccttttcc tgacaaatcc gactgatttc
    34261 cactaaaacc ttcggagaca ttcctcttgg taaactccca gaaacacaaa gataatcctc
    34321 tgcttgtaat gctcttattt gatttaaaaa attatggaca gctgcctgcg gtatttcagg
    34381 tccttgattc actaatttgt attcttctct cgtttgattg acttgtgtaa atacattgat
    34441 acgcgtcata ccaggcactt caataaactc tgtttggatt tgtttcttct gtaaatagtc
    34501 ttctatatat tttcctgtga aaccagcaga aaaacctaat gccgtacttg ggaaatctag
    34561 catctttaat actagtgaca catttactcc ttttccgttt gcctgaatgt catcctcctt
    34621 tgtacggttt accataaaag gatgcatctc ctctgtttca ataaatagat caattgccaa
    34681 attcatcgtg catgtgtaga tagacataac caatgacctc cttgaatcta ttatgaaata
    34741 cgcgaaagag aaaatgtttt cttaatcgtt ccaacacaaa gaaaaccttt acatttataa
    34801 acacatcgtg ctatttttta actaactttt agtgaaagaa ggaaagaata tggatcacaa
    34861 attaagtgaa acagaacagt acctctggaa ctttatcgaa caccacatcc tagagatccc
    34921 taactactcc atcgtgaaac taagtgaaca agcaaatgtc tcaacagcca ccattgtgcg
    34981 gacaatgaag aaaaaaggct atgaaggatt tacttcgttt aagcaccatc taaaagaagg
    35041 agaaaacaag aacatcaatt tttcttttta gataaagtag acaaaggtat ccgtcgagcc
    35101 attctaaaaa atgaacaaga agtggtacgt acgatcaata tgttggaaat cgggaacatt
    35161 gaagatgcaa tacaaagaat caaatttact gaccgggttt ttgtctttgc ccgaggattt
    35221 tcagaaatga ttggtcaaga gatgctcgta aaacttcaat taacaggaaa aaattgtcaa
    35281 atgcatactg atccagagat tatcaaaagc atcagtcgga aactaactaa gaaagacagc
    35341 gttatttttg tttctttgaa cggcgagaca aaagaactcg tcaccgccgc aaagaactgc
    35401 tatgatgcag agattggttc gattctagtt acagccaatc attcctctac actcaaagat
    35461 tattgcgaga taaatctcgt aggtttcaaa tcagaaggtt cttatttccc tgattatgaa
    35521 gtacgttcac gcttgcctct ccagatcatc gcgagaatcc tgcttgacgc ctatgtattg
    35581 cgtatgaggg agaattgaga agcagtttat tatggttggt tacagtttaa aacatcacat
    35641 tttttattct ttatattgta tggactcacg taaacttttt atgtataaag ttattcacaa
    35701 tctataaagt tattttaagt aacaaaaaat aattgaaaat acttaaaatc aaaaaatatc
    35761 tttttaatca ataaaaaaat tgacagtttt attaataata agctattctg ttatagaaga
    35821 aaaaattgtt tgttattatt agcaacaaaa aaaggagtgc atcatgaaaa agttatctca
    35881 aaaacgttta gctcaaatca ttattgattc tagaaaatct ctgaaaatga cacaacaaca
    35941 acttgcagta gctactggta tcaaccgtgc cttaattagt cgagtagaat ctctcgattt
    36001 tatcccgtca atacaacaat tagaatcatt agcagaagtt ctaaattttg aaccaacaga
    36061 tctatttata aatgaatcaa ataaatcaaa cagaacaaaa catcagtcga agaatattgc
    36121 tgtagccggt actggttacg taggtctttc cattgctact cttcttgccc agcacaatca
    36181 ggtaacagca gtagacattc ttcctgaaaa agtaaaacaa attaacaata agaaatctcc
    36241 aatacaagac gattacattg aaaaatatct agctgaaaaa aatcttaatt taattgcaac
    36301 gactgatggt gcagccgcct atagagaagc cgattttgtt gtcattgctg ctccaacaaa
    36361 ttatgatagt aaacaaaatt attttgatac ttctgctgta gagtcagtaa tcaaattggt
    36421 gttagaagtc aatccaaagg caataatggt catcaagtcg acggtacccg taggctatac
    36481 cgaaagtatt cgtaaaaaat acaatactaa aaatattcta ttcagcccag aatttctcag
    36541 agaatctaag gcattatatg acaatctata tccttcgcga attattgtcg gcacggacca
    36601 aactgacaaa actttacgag aagcctctca cacttttgca gatttactcc aagaaggagc
    36661 aatcaaaaaa gatatcgaaa ctcttttcat gggattcaca gaagctgaag cagttaaatt
    36721 attcgctaat acttaccttg cacttcgagt atcttacttc aatgagctgg atacttatgc
    36781 agaaatgaaa ggactaaata cacaagaaat cattcacggg gtttgcttag atccaagaat
    36841 tggcacacat tataataatc catcttttgg atatggaggc tattgtttac cgaaagatac
    36901 aaaacaactt ctcactaact ataacgatgt tcctcagaat atgataagtg caattgtcga
    36961 tagtaatcgt acaagaaaag actttatagc agatcgagtg ttagaacttg ctggcacgta
    37021 tgaggctaac agttcgtgga atgcagaaaa agaaaaagag gtagtcatag gtgtataccg
    37081 tcttacaatg aagagtaatt cagacaactt ccgtcagtca tctattcaag gagttatgaa
    37141 gcgaattaaa gcaaaggggg caactattgt aatttatgaa ccaacacttg aaaataacac
    37201 tacatttttt ggttcaaaag taataaataa tttagatgat tttaaaaata tcagtcacag
    37261 tattattgct aatcgttacg atagtaatct tgatgatgta aaagaaaaag tatataccag
    37321 agatttattt caacgagatt aaaaaataac acctcagatt tgtagtgtct gaggtgtttc
    37381 tataaacttt tataagtaaa aaaatacaat tatacttcat aaaaagactt ataccactgc
    37441 gcaaatttac gaagcccgtc acgcaaactt gtacttggtt taaattcaaa atctcgttct
    37501 aacgcactag tatctgcata agtaactggc acatctcctg gttgcattgg aactagttcg
    37561 gtatgagatt caaagtcgta atcttctggt agcacccctg ctgcaattag ctcttgttgt
    37621 agaatatcta caaaatctag taggttttcc ggcgtattgt taccaatatt ataaatatga
    37681 tatggtggga ttggtagccc atcttcccca tcaattttct ctggagcgca ctgcataacc
    37741 ctctttactc cttcaacaat atcatctata taggtaaagt cacgcttgca attcccataa
    37801 ttgaatattt ggatattatc accagcacga agtttatcag taaaaccaaa ataagccata
    37861 tctggacgac cagcaggacc atatactgta aagaaacgta gccctgtaga cggaatattg
    37921 taaagtttag aatatgcatg tgccattgat tcattacttt tcttagttgc tgcatacaac
    37981 gatacttgat tgtctacttt atcctctgta gaataaggaa ttttcttatt agtaccataa
    38041 acggaagacg atgaggcata cactaaatgt tccacaccag attctccatt atcatatgaa
    38101 tgacgacaag cttcaagaat attatagaat cctattatgt tagattcgat atacatatct
    38161 ggattagtaa ttgaataacg gactcctgcc tgagctgcta aattcaccac gatacttggt
    38221 ttataattat caaagaggaa atcaattgtt gctttatcag caatagaacc tttgataaaa
    38281 ttccaagtag atcctggatg gttctttgcc tccgtttcta tctctgataa tctatagttc
    38341 ttaatagaga catcatagta atcattcata ttgtcaatgc caatgatttt tattgatgac
    38401 tgagtacgta ataactcaag aaccaaattt gatccaataa aaccggctgc gccagttatt
    38461 aatattgttt tattctgtaa agatgtattt tttttcagca tctagttata ctcccttatt
    38521 tttatttcat catatgaatt aattaaatgt cttcataatt tgcaacaagt tatgttcaaa
    38581 ggcatcataa ctatatagtt ctgctctctt ttttgctgct tttgcatact tattcctcaa
    38641 attatcgttt tcaatcaatt cttctatagc attcgctaaa tttttatcac attcttcata
    38701 ttggggcgaa taatttctac tgtctgtcat tggacatact aatatgcctg attcagcata
    38761 ttctatattt tcacaaatcg tgtctagcgt tctattcgat aatatttctc ttggcccaga
    38821 tttgcaatct gcacataaga cagcagtttc tgtagacatt gcttcaacta atgcattagg
    38881 aaaaccttca gttatagatg gcatgacata taaatctgca cgtgacatgt atttataagg
    38941 atttgattgg ccacctagca aaaatattac gttttgtagt tgatatgctt ttattaaatt
    39001 ttctaataat tctttttttg tcccatgtcc taagatgtac acaacaacat tatctttgtt
    39061 ctttaacata gatatagctt taattagatg atataaacct ttttgatctt ctaatcgacc
    39121 aaccgtcact ataatttttt tgtctgttgg aacctctatt tctgtaattt tttctttact
    39181 cttattattt atcaactcta aatcatatgg attatataaa aaatagcttt tatccttatt
    39241 aaaattgaaa atattttcag catcacgttt aattaactga ctgacagaca caacagcatc
    39301 tgctttctta tatacaaatt tatctacata gtaatggaat atatattgaa atagccagtc
    39361 ataggaccgg attccaacat atactttatc atctctcttt gataaaacat ttactaaatt
    39421 acaactttgt ccaaaagata tagttatatc cgttttcaat ttttttttga cacttttcat
    39481 tttataaact cttttaaaaa tgttaattac tttaccaaat tttgatggct ttatatcaca
    39541 ttttaatgat aaatattcaa aatttggctg ataatctgca tcgttatcaa aaagagttac
    39601 aaatgataca ttataattat ttttcaaaag tatttgacgc gttataaaag ctactctttc
    39661 cattccacca taatacattc caggaattaa aattgttact tttttcattt tcctaatcac
    39721 aaccttgcca taaaaatctc tcttaatatc ctttaccagt aaacattcta accatattaa
    39781 ttatttctgt ttttccttta aatatacaac tatatataaa aaaatataga attacacaaa
    39841 gacacactga aagtaattgc ataacataat tagtacagaa ttccaacata atttttgcta
    39901 gaactcccat tagcaatgca ctagcacaag atttccaaac ctgctttaaa attttaaatg
    39961 gattaaactt aaaaccaaac cataaaataa tccaaaagac tataatctgc tctatcttaa
    40021 cgaaagatct accatatgct agttctataa accctttcct tgaatagatt attagaactg
    40081 gaattaatac tgctaaatgt aggatagtca taagaacatt tgcttttggt tttcctaaac
    40141 cacgatagta ctcagaggca tattgtccca agacaagagt aaaacagctc attaatccat
    40201 atatcccaac aaatggtaca gcctctttcc attgactccc gagtagaata tttgttacta
    40261 gttccctata tacatatata cctataccca gaggaataat aaaaatggaa acaattttaa
    40321 taaaatctaa atatgtctta tcatactccg ttttactatt ttgtaaacga gataatgttg
    40381 aaaataatac agttgttgtt gctgaagtta caattgcaaa aataccatta accgttgtca
    40441 ttgtagtttt gtatattccc aaatagtata cgcttaaaat gcctcctacg ataaaagtac
    40501 ctatataaga tgacaaccat gtacctaatg attccactag tgaccacgca ctaaaggaaa
    40561 acatttcgta aaattctttt tttgaaaaaa aaagttttgg tttccactct gataacttag
    40621 ttaatattgc agctgtaact aaatttccta ttatagatcc aattactagt gaccaataac
    40681 ttagtccaat tatcgccaac ggtactgtaa taactaaagg tatcaatgca gatattattc
    40741 tagcataaca caaaattttg taatcaaaat ttcgtctaaa aattgccgat tgtatactgg
    40801 aaaaagaagt aattggaaga gaaactccag ctactataat tactaatcca agtccagaat
    40861 ttccaactaa gtgcgctatt ttattattaa acacacaaat aaataaccat aataataaag
    40921 aaatacctaa gttactagta aaagctacat ttgttgatga aaacatgtgt tcttcattat
    40981 caaattcatg ctgtactaaa aatttttgaa atcctgaatc actaaacata tcagcgaaac
    41041 taataaccat agttacagtg gctactactc caaaagcatc tggagtcaat aatctagcta
    41101 aaatcatatt cgaaattgga gttataatct ttgcaattat ttcagctaag gatgaccatt
    41161 ttaaagcttt tgctgtcttt ccatgaatat tatttcccat ttattacccc attttgctaa
    41221 ataaatatag caacctttcg catattaaac attacttttt aatcaaattt ataatcaaat
    41281 ttcaactctg ttatgattgc tggatttcca tatactaagc tatatggtgg aacacttttt
    41341 gtaactacag catttgcacc tatgattgaa tcatgtccga tattaattgg tcctaaaaca
    41401 catgcaccag cgaaaacagc cacattttcc tctagcgttg gtgccccaac agtttctttt
    41461 ccatttatta ttttgccatt tccacccaaa gtcacatttt gatatatttt acaattatta
    41521 ccgatttttg ttttagggtg gaatacacaa ccaagaccat tatggactag ttgagcatta
    41581 gagctaaaat ctacctgtcc gtagaattca catccataaa taatccttaa aatatagcag
    41641 gatatttttg acattttatt ttgaccattc ctgtattgtc tacaagcttt atctgcccat
    41701 ttctctgctt ttcttctcat tttttctacc tcaactttct ttttttatag ttctttctga
    41761 tgcagaaatc atacacaaaa caactattgc gtaaagaaaa cgcgaagata caatatccgg
    41821 tataaacatt gctcccacta ctatcatcaa aaataaccat ttatagcaac ctgatttctt
    41881 taattcttca tacgtaaatt taaagaagcc acttaaaata attagcgtac caataattcc
    41941 tgtctgtaat aaatattgaa taaaaaaatt atgtggtact gctacaccta gtagcgtgta
    42001 taaattattt aatcctaatc catatcctat taagtattta tcactaaaag catttaaaga
    42061 ggacatatag ttttctaatc tgcctgaaga atccaaaaga ctttgtccag aacgacctgc
    42121 cattaacatt actagtatat aaggtgtagt tatgattcca cctattagaa ctaaaagatg
    42181 aggaacacta attctattta tattaaatag ataatacaat gtcattgtga caaacaagga
    42241 aactaaccct gttcttgcac taacacataa aattgcacct aataaaaata cttctattat
    42301 tataaagaat aataatttcc aattttttaa atccacatat tttagaaaag catatagaca
    42361 gcctgtagca agatataacc ctgcaaaact aaaatctccc atcaaacctg catatgcaat
    42421 tctatttaaa cccatttctg cataatggcc tattattaca ccagtagata aaatatatac
    42481 tcgttgcaaa tatacctgaa acgccataga tactactcct atgaaataga aattccaccc
    42541 aatcatagtt aagtttttgc tatacatttt aaaacgtttt cctattaaaa aactacagat
    42601 aaacaacgaa atagtcatta attgctttaa tgcatctatt aaaaaaggta agaacataga
    42661 cgtcgatatt ccaaaacaaa taaataaaaa taaaataatc aagtatgaac gatttaatgt
    42721 tccttctata ataatatata acatcaaaat tattattatt agattatgcc acgtcaatgg
    42781 taagctagaa taactagttc ctaatataga tatagttgat gttggaatga aaagaattga
    42841 tgttaacaat aagctatctg ctaaacaaaa atactttttt aagcaccaca tataatacaa
    42901 aaacataaaa aaagaaacaa ctgcaattgc tattgagggc atcagtgaat aaaaaatcat
    42961 tcctgattga aacaaaatac taatgggtat tatttttcgt aaaactaatt gatctctatt
    43021 tttataattc atattttatt ttaaagctgc agatacataa attttttcta atactccttg
    43081 ataacgattc atattagaaa atttctttgc actaatagca gcattttctc ccattttttt
    43141 tctaagttct tctgaattta atagcttcat tagtgaatta gataattcaa cttcactacc
    43201 acacagaaat ccatttgtct catcgataat atccttcaat cctcctacgt tataagctac
    43261 aacaggcgtc tctaacaaca ttgcctctac tgatactagg ccaaaccctt cccaaagaga
    43321 tggcattaat agaactttag atttcttcat gtacttatag ggattacttt tgaatccctt
    43381 taactcaata acatctgtta agtttctttt ttgtatttgc atcttaactt catcaaataa
    43441 tggtccttca ccaatcatca cgacacgtaa atgttttgaa tattttttta ctacattttc
    43501 taaaacatta attgcaccta ttggattttt aggttctgcc atgcgtccta catataaaat
    43561 atcaatatca tcttcaacaa attcattccc catttttata attctttcag tatttacagt
    43621 gttaggtaac aacacaaatt tatcttttat taattgtttg taacgaaatt cttccttaac
    43681 ggaattcgaa acaccaatta ctgaattaaa cctagacgaa cataaagaat atataatagt
    43741 tcttatgtct agtttaggta accacaaggg attattgtgc aaatgggaaa ggatgatttg
    43801 cttcttatat ctacttgctc ttacactagc attaaaatca tgagcatgaa ttatatctgg
    43861 gtttaattca tgtacggctc tgtcaatttc ttttctcgaa aattttttta atggtaagta
    43921 acttaaacct ctaatattta aaatatttgc tataggacca tctgggctaa cgtaaatcat
    43981 ctcaaatttt tcgttatttt gaaataaact cattatttga caaacaatat tttcagcgcc
    44041 agaaaatcta ttactttgca acaaatgcat aatttttatt tttttcatat taatatcact
    44101 ttcaattcaa ttatttactt acaatttcat ggtaaacatt atttatttgg tttatcacaa
    44161 ctgataaatc aaaatctttt atcttgtcta aattatgtgc ccccatagat tcacacaata
    44221 atttgttatc agccaatcta tttatcgcac cagcaatttc ttcttcgtct ttaggattga
    44281 ttagaaatcc acccttacca tcttctataa gatctacatt tcctcttata ttaccgacaa
    44341 tacatggtaa accactagcc atcgcttcca ttaaagaggc gttgaggcct tcccttaatg
    44401 agggtagaat atatatgttt gcagcagcta ataatttggg tatatcactt ctatatccta
    44461 gtaaaaaaac tcgctgatgt aatcctaatt cattagcaat attttgtagt gtctccctca
    44521 tttctcctac cccagcgata atataataga tatctgtatg cagcggaatt ttttgtaatg
    44581 catgtattac tgataaatgg tttttattct catttagctc tcctacagat aaaatgattt
    44641 ttgctgtatc aggtatatta agttctttac atatactttc tctaaaattc cttattgatg
    44701 tggaagacat aaacctattt gtatctatac ccacacctgg aatataataa gcttttccac
    44761 ctttcctaag acgaagtttt tgagctaaag tataatcctc atgatttatt gtaatcaaaa
    44821 catctgtata atgagctagc caacgttcca taggataata tataaaccaa tttattttag
    44881 gagcacctga ataaaaatga aatccatgtg cctggtaaat tacttttttg actttacatt
    44941 taagaccagc aatccgtccg acaacacctc caataggtgt attacaatgg ataatatcta
    45001 ttttttcatt ttttataatc tctacaatct gatgataagc ttttatattt tttaaattta
    45061 gtgggtttct ataaaaatca acttggtata tttttattcc atatttcact tcatcagctt
    45121 ttctttcctc atcggatttg tatttccagt taccagctat ataaaattct aaacccgttt
    45181 gtttagctgc catcatacta gctttagaaa agttatttac tttattagct acatttaaaa
    45241 tatacaataa tttcataatt aattcttctc catataaaac cgatattcat tcataattct
    45301 tccttcatta gtagaatatt tacgttctaa aatgaactca ttctttttat aaaaattatt
    45361 cacaacatca ttatttaatg catctgtttc tagtgcaata tattcatatt ttgaaaaatc
    45421 aattctactc tttaagttat ctataagcat ggaacctact cctatcgatt tctctttcgg
    45481 attaactcca atggatgcta attccacata attttcatca cgttttgttt cgcttggttt
    45541 tagaaaagct ctaaaaagcc tcataaggat attgggtttc tttataaagg ctacacaact
    45601 ataaaatcca aacggtatta ttcttttctt tatcatatac ttatataaac cactcatatc
    45661 tccagaatat gcaagaaatc ctattggctt atcattttga atagcaacca atataccaga
    45721 atcattatat tctgtgtaag aacgatacat caattccaaa aacttttttc ccatgaaagt
    45781 caaaaaaaaa tttgtaaatg ttctcatatg aatatcgaca atcgaattaa ttaactcttt
    45841 atccgaactt tttatctctt caatcaccaa aactcttatc ctccattcat tttatctgat
    45901 taataaactc tcgttcacct tctaagtcgg cgtgatattc tttaccaaat ataacaaaaa
    45961 tagttttaca cattattttc aaatcattca tacaactaaa ttcactgata cttttcaaat
    46021 tgtaatacat tttactggga agaatttttt ctatataagt tttgtcgatg ttatttttat
    46081 catgcaacaa tttatcttca tctttgtata aaatactagt ttctgatgta atcccggctg
    46141 gtaataataa tgtggctaac attaatggtg aatacgactt tacatatttt ccaacttctg
    46201 gtctggttcc tacaaaagac atatctccga ccaaaacgtt aattagctga ctaatttcat
    46261 ctaatctata tttacggatt acctttccta ctcttgtaat acgatcatca tttttcacag
    46321 taacaagagt gccatcttta tctgcattta ttaccatagt acgaaactta taaattttaa
    46381 atttttttcc ataacgagta atacgttctt gtctataaaa tacaggtcca ggagaatcaa
    46441 tttttatcac tattgcaaga ataaaaaata accatgaaag tgtcagtaac aaagttgcag
    46501 acactaaaat atcaaatact ctttttacca ctaagctgaa ttttttttta ctgaggatat
    46561 cataataata ccgtatttca tcattctgca tttcttttgg caaatcttcc cactttctca
    46621 ttttgcctct cctatcatcc aaccaaatcc tttacaatct tactatagtt attaattacg
    46681 tattctactt cttcatctgt aagtttcgtg tgcaatggta atgtaatctc atttacaaaa
    46741 tgagcatagg cattaggata gttattaata tcaaacccca tatttttata tgctgtaaac
    46801 attggaagtg gtttatagtg aacgttgcaa gcaatccctt gttctgccat ttttataatt
    46861 atttcatttc tttgctcaga actaatgtta ggtactctag taatatataa atggcctgaa
    46921 gaactataat catccgtata atgcataaga acttcaattc ctagttgttg aaaggcttca
    46981 tcatacctct taattatatt ctttcttctt ttcagaatat taggatagcg ttcaaattgt
    47041 gccaacccaa ttgatgcagt aacatcagtc atattacatt tataccatgg acccacaata
    47101 tcatattccc atgcacccaa ctgtgtttta gtaagtgcat cttttgactg tccatgcaaa
    47161 gaaagcagct ggcactgatg atacattgcc tcattatcta gtttgtcgtg ctctttccat
    47221 actaaagctc caccttctgc agttgtaaaa ttcttaacag catgaaatga aaatgttgtc
    47281 aagtcagcaa cattaccaac catctgatca tgccaattag ctccaaatgc atgagcagaa
    47341 tctgccataa caattatacg accataagct ttctgaatct cattactagg ttgaaataaa
    47401 tttctttttt tctccacaat ctcaaaaata cggtcgtagt cacaaggtat accaccaaga
    47461 tcaacaggaa taatcacttt tgtcttctcc gtaattgctg cttctaatgc atcgtaatcc
    47521 atctccaaag aatcttgttg acagtctatt aatactaggt tcgcgcctat gtggcataca
    47581 accgatgcac tggcagaata agtataagct gggacgataa cctcatcatt ttctcctatt
    47641 cccagcaaac gtaaccctgt ttctgcagca gcagtttgtg aatttaaaca aactacttta
    47701 gaagttccta accactttgt aatttttttt tctaattttt ttgtctttgg tcccgtagtt
    47761 atccatccag attttaatac ttctacaacg ttttttattt ctaaatcagt aatatctggc
    47821 ggtgaaaatg gtatctgacg tttttctaat ttattcattt atatttcccc cctatttatt
    47881 cgaagcattt gcaaaagtga cgatatcttt agccaattgt tcatcgtctt gcggcaggct
    47941 cttgacaaaa tccatcactt tttgtattga gtaacctttg atgtttccta caaagatttt
    48001 ctcataaact gcttcatcat ttctttcctt atccaacagt agttcttcat atagtttttc
    48061 ccctggacgg atacctgttt caatgatttc gatttcgtct tcgctatacc cgctcaatcg
    48121 gatcatgttt ttggctaggt ctacaatctt cactggttca ctcatatcta gaataaaaat
    48181 ttcgccacct tttgctaatg cgccagattg aataactaaa cgactagctt caggaatcgt
    48241 catgaagtat cgggtcatac gaaagtctgt tacagtgatt ggaccacctt tagcaatttg
    48301 ttctctgaat actggaatca cactaccgcg agaaccaagg acattcccaa atctgacagc
    48361 tgagaatttc gtacagcctt cttcattcaa tccagtcacg atcatttcag cgattcgttt
    48421 tgttgaaccc atgacatttg gaggattgtt agctttatct gtcgatacca tgacgaagtt
    48481 tttcactttt gctgctttag ctgcttctgc tacatttttt gtaccgaaaa tattgttttt
    48541 gactgcttct tttggattat attccatcag tggtacatgt ttatgagcag ctgcatggta
    48601 gacgatatct ggatgatatt gttccatgat ctcattgatt ttctcgcgat cttggatatc
    48661 tgcgatgatc ggtacgattt ctgtaggaca attttgatga tgcgtgcgta actcacggtc
    48721 aatcaagtag atcgagttct ccccatgtcc taaaagcaat agctttgcag gattgaattg
    48781 aatgatttgc cgacagattt ctgaaccgat cgatcctcct gcgccggtga caagaatgac
    48841 tttgtctgtg atctgatctt tgatggattc aatatccagc tttacctcat ctcttcccag
    48901 taaatccact acgtcaattg tttttaattt tgatacgcta atttttcctg aagcaagttc
    48961 ttctatagaa ggcatcgtgt tgactttcac gtgagcggat tcgactaact cgaagattct
    49021 tcgtaatttt tttcttgata aggaagggat agcgatcgtt accatttgaa tgtcatattt
    49081 ttcaatcaat tccggaatat cttttaatgc acctaatact ttttttcctg aaagatacgt
    49141 atttctttta ttcggatcat catctacaaa tccgacaact tggatatctt gagccgtttt
    49201 ggatcccaga aagctgttgt ataaaatacg cccgccttcg ccagcaccaa cgatcaatgt
    49261 atttttagca gaatccgctg atacatatct catatttttt gtttcgatgt agatacgcca
    49321 gatcaatcgg ctaccgatga tcaataagag cgaaagcaga taagcaaaga taactaaccg
    49381 taaactgtat tgccgattaa tgaacagcag tatgaggata cttgagacgt cacttgcaga
    49441 tagtgaacca aaaattgcaa tgatctctct taaatttgta tagcgattga tccgagtgaa
    49501 aactttgaat aaactaccat aaaataaata aaaaccaatc gacaaaccgg tagagattaa
    49561 aataaggtcc attggtatag ctacaaacgg cttcatgaat ttagctgctg caatatttgc
    49621 agcgatcaat aacaaactgt ccacaacaac caatgtggca atttttcttc ttcttgttaa
    49681 tacaaacacc ttacactccc cctaaaataa accaaacttc ttctttttta tctcttcata
    49741 gactggataa ctgatttcat ccccgttgat cagatccttt gcgacttgtt tcatctgtac
    49801 tactttttcc ttaccaaagt ccttggcaat ctgcttatag cactctttta agtaaaaggt
    49861 gcgcttagag accccatggg catcagaagc agccatctgc acaagattat gtttgaccat
    49921 cattttggct gttttctgga tgtcttttcc aaatacaccg acataacttg gtgcggtgag
    49981 ttgggccaag catcccatat ctaggaatgg cagcatatga ttcgggtctt tacgaaaatg
    50041 cgcgttgcgt tctggatgga cgatcactgg tgtctttcct agttgtaaca actcaaaaaa
    50101 gagctgttct gcatataacg gcacttccag tgtcggaaat tcgattagaa gatatgtatc
    50161 atctaaatct gtaaataaaa tttcatctcg gtcgatgtct tcgatcagtg ttccggtaat
    50221 acgtacttct tgtccttcca ataacgtcaa aggcaattgt cttttctcta attctgcttg
    50281 taacgaagcg actagagaaa tgacttgtga tttttcattg ctgtattttc cattattatg
    50341 atggggtgtg cataaaatat gtgtgatccc ttgttgaatc gctttttcag ccatggcgat
    50401 actggcatct atgttttctg ctccgtcatc gattcctggc aggatatggc aatgtagatc
    50461 gatcatttct cttgtctcct ctctttttat ttcttaattc ccgtagtaat agccagcatc
    50521 tttgctgtgt tctgccccat tgtatacaac accaaggact cgcgcttgta ccatatccag
    50581 caattctttt gctttagtca atgattcttt ccgtgacata ttttcacgta cgaccaataa
    50641 ggtgccatcc gttttggaag acatgatctg tgcatctgtt acggcaacta ctggcggcat
    50701 gtcgaagatc actacatcaa atagttgtct tgcttctgct aaaatctgat ccattcttgg
    50761 cgaacttagt agttctgatg gatttggtgg tttaggtcca cttggcagaa tcgacaaatt
    50821 ctcgactggt gttcgttgga tctcatctgc tacacttcct gatgaactaa gaacggtact
    50881 taatccgctt gcgttgttca acttgaacgt tttatagatg acgggcttac gtaagtctgc
    50941 atcgactagc agcacccgtt gaccagattt ggcaaaaaca acggcaatgt ttgctgcagt
    51001 ggtcgatttc ccttctccag gtcctgatga agtcacaaca atcgttttaa tttgctgacc
    51061 agctgcggag gcaaactgga tattcgtccg aatcgtacga tattgttcag cgattggtga
    51121 agaggggttt gtgagtgtga ccaaactgac tgcatgagtt tgggctgctt tttgtttctg
    51181 tgttcgtgcc atttttcttt cctcctagac tcttgagcgg cttctgcgtg atggcgctgt
    51241 tttatcgttt gtagcttttg gttgtgtcgg agctggtcct tttttacgga taccagcatt
    51301 caattctttc gctgacattt ctggtacagt ccctaagatc gggaagccca atgtatccgt
    51361 cacatatttt tcatctttta ctgtccggtc gagtaattca aataagaaag ctagacctac
    51421 gcctaccatc attcctaaca ctaagccaat cactagattc aatttattat ttggcgaaac
    51481 aggtgtcgta ttggcaactg cacctgagat gatcgagatt ttatcgacat tcatcacgtc
    51541 tttggcgttc tcttggaata cttgtgacgt tgtattagcg atttgttgag ccgtcactgc
    51601 atttgtgctt gttgcttgga tcgagaacat ttgtgaattt tgtgactgat tgacggagat
    51661 ggcatctttg atttgtccag cagtcatttt tacattgtct tctgtttcta aacgatcttt
    51721 gacttcattt agtactagat cactgacgat catatcctta tacgtattga tcatttgcag
    51781 gttcgtattg acatcattga catttgcagt atctgattgc ggcagtgtca cgatcaattg
    51841 ggcttgtgag ctgtattttg gcgtcaagat gaaaaacgtc acgatgcctg agatggccaa
    51901 gccagcaaac attgagatga ggattgttat cacgtgtttg cgtaatgttt caaaaatttc
    51961 tttcaagctg attgtctctt ccattttttc tccactttcc tatttattct ctagattcat
    52021 ttgatctttt aattcttttt tcacacgatc aagttcttga tcgctgactt tttggtatga
    52081 gatattgtct tgcatgaagc cttctccttg cagctgatct tgcttgatcg taccaaatgc
    52141 atcccgataa tctaaagcaa tctttttcat ttcatcaaag ctcatgtctg ttttcatatt
    52201 cgactctaga gcattcaaaa cggattgata gttgcttaca ccgttcagac tcaacacttt
    52261 tttcgctaca ccttctacga tctttctttg acgttcttgt ctgccgtagt caccatttgg
    52321 atcttcataa cgcatacgag aataagacaa tgcctgatcc ccgttcaatg tgattttacc
    52381 gatcgtaaaa tcatagccat cttgtgagaa ggtgaggtca ttattgactt cgataccacc
    52441 aactgcatca acgagttctt ttagaccttt catattgatt gaaacatagt gatcgattgg
    52501 gatgtctaca tatttttgta cggtatccat cgccatggca gctccgccga atgcgtaagc
    52561 gtggttgatc ttgtcttttg tgtcatgtcc aacgatgtcg acatacgtat cacgaggaat
    52621 gctgacaatc gttgtctgtt tgtcttcagg actgactgtg gcaaccatca tcgtatctga
    52681 tcttccttga tcgacccgac ctaaatctcc cgtatcaatc cccatcaata gaacagagaa
    52741 agattcttgt ttgtccagat caactggttt tgttcgttct ccttgggttc gttccactga
    52801 ttcgtaagtt ttttcaatag aatgtgagag atctagatat aattttgctc ctactcctac
    52861 gattgctaat actaatacga caagaattgc taaaataatt agaaatatct ttttccctct
    52921 tgatcttctt cttcgttttg ccatagtttc ctccgtttgc tagccttgct tgaattctcg
    52981 cttattaata gctcgtattg ctatagccca tttgctgagc gactgtttct gcttttgacg
    53041 cgtatgcggc tcttattttt tcattccgga tctgttcgat gagactgagt gcggtcaaat
    53101 attgatcgta agtagcagta gctgttactt gaccgtcttt cagcatcgta tcgaatagct
    53161 gatctagttg cgtgacttgt gcaatttggg tatcagcgaa tcctagatat tgcataacga
    53221 ccgttttcca agcactatcc ttaaaaaagc tcatattttc acgtacatgg gcgacatctg
    53281 cacttgccaa cttttctttg atgatgacat catccacagc ttgctgccag tttgatacgt
    53341 ttttagtaaa taatttattg acagccgttt ggatcttcag ttttgattct gcatcctcta
    53401 actgtgttaa gactgctttc ttttcttctt ggatcgcagc agcttcttta ggtaattctg
    53461 attccttgat gtcataatca tctgctgaaa gtttgataga agatagttta tgtgacaaat
    53521 ttgaaactgt ttcttctgtt atttcaggat ttaggaaaat tttttctttt gtactgtaca
    53581 gcttatctac ttcttttgat aaagaggtca cggtgtcttt ttgattggtg atggcagatt
    53641 ctgcgtaatt gatccgttga tgatgttgcc gctgattatt gagatggtat ccaaacaagc
    53701 aaatcacaat agcgcctgtg cctaccgcca cagtagccaa taacttgacg aacggctttt
    53761 ccatagattc actcctaaat attgatgata gataaataaa gatgtgattc attcacatca
    53821 gaatgagcgc tttttatttt aaaagcataa ttaaactaat atattcatag aaatatttat
    53881 aaacaggttt tccctatata atcataccac aaacagtttt cttgactagg gaaattccta
    53941 atttaaaagt aaataaaaca gtaacaagat tattattaat ctttttcatt tttatttcct
    54001 cacttttcat gagcgttttg aaaattctag caaagaataa aataacaaaa attattaaaa
    54061 tagaattaat aacagctttt atatttataa caaaaaaaca gagacacagc acgtttcgtg
    54121 catgctctct gtttttcaaa caaaagacta ttttgtgatg atttgatcca agcttgctaa
    54181 tgacaaagcc atggcagtta tttgactaag ttgtgttagt cggttcttac gtactgctgg
    54241 ttcatcagcc atgaccatcg tttgatcaaa ataattttcg atcagtggac gaagagcgac
    54301 aagctggtcg tagttttcgt ggatcgtttg gtcagcaaaa cttgctttca ttgcttctac
    54361 tgctttgtgt aattctttct ctgcgtcgtt ttcgaacagc tcagggtcta cttctgattg
    54421 tttttcaagc tgcgcttttt tcgctaagtt cacgacacgt gtcaatgctt ccattgaagg
    54481 tttgaagtct tcatctgcaa gatgttgttt gaacaattgt gctgctgcaa atacttttgt
    54541 cagatctttt tgttctgcat tcaaaacagc ttcgatgaca tcatgacgga tattcttcgt
    54601 tgtcaataat tggcgcagac ggcctttgat aaagtcgatc acctgttgtt gtcccgctga
    54661 caagccaatg ccaaaacgat ccgtatcttt actgataact tcactaatcg tttcttgcag
    54721 aacagacaaa ggaaaggccc attttttcga ttcgatgatt cgaacgacac catatgcttg
    54781 acggcgcaaa gcatatggat cgtttgagcc acttgggatc atcccaactg caaagaaaga
    54841 aaagatacta tctaatttat cagcaatcgc taaaacagaa cctactgtag tctcaggtaa
    54901 atctccttca ctggatatag gcatgtaatg ttcacggatc gctgttgcta cggctggttt
    54961 ctcgccttta agcagagcat atttttctcc catgatccct tgtagttcag ggaattctcc
    55021 taccatgttg gttactagat caaatttata gatttcagca gcgcgttgca gatccatcaa
    55081 ttcttcctca gatagtccta cttgttcgcc tatgatgcga gcgatgactt gtacccgttg
    55141 cattttctca tagatgctac cgattttttc atggaaagta acagttttta atttttcaac
    55201 gtattggtcg attgaagctt tcttgtcttc attataaaag aattccgcat cttctaaacg
    55261 agcagtcaat actttttgat tgcctcgtac cacattttcc aattttaccc gatcgccatt
    55321 acgagcagaa ataaaatgag gaagcaacat accttgatcg ttccgtactt cgaaataacg
    55381 ttgatgttct ttcatagaag tgactagtac ttcttcagga acagatagat atttttcttc
    55441 gaagtcgcca gaaaagacag ttggatattc gactagattg ttgacttctt ctagtaaatc
    55501 ttcatctaga tcaatgatcc agtgattttt ttctgctaat tcgtttgctt gtgtgatgat
    55561 catttctttt cttttttgcg gtgaagcaat aacaaattgt tcattcaatt tttcttcgta
    55621 ttcttttgca tgcgtaaatg tcacatcttc gcctaagaaa cgatgacctc ttgaaactct
    55681 gtctgttttg acatccaaga tctcaaacgg gattatttcg tcatctaaca atgccacgat
    55741 ccagtgaata gggcgaatat attcaaaatc gtattctgcc cagtgcatcg ttactgggaa
    55801 agtgaggctt ttaatgacat ctgctaaacc tgtcaatact tcttttgctt ctttgccgtg
    55861 agtgtatttc gttacataga catattccac gccttttaat tctctaaaag tgatagcatc
    55921 tgtcgtcaga ccttgtccgc ggacaaatcc ttcagctgct ttcgtccagt ttccatctgc
    55981 gtccaaagca atttttttgg ctggtccttt gacttcttct tcgctgtctg cttgacgttc
    56041 tggaatgttt gttactttga ttgctaagcg gcgcggtgta gaaaacgttt cgatcgtatc
    56101 ataagtcaat tggttttcat ctaaaaattt tgctgttttt tcttctaatt gtttcatgct
    56161 tggtgtgact acatgagcag gcatttcttc cagcccgatt tcaagtaata agtcttttgc
    56221 catcttattc agcctccttc acgttttctg gatttgctgt gtttttattc aataaaggga
    56281 atcctaattt ttcgcgttct gccacaaaga ttttggctac agcacgagcc atgttgcgga
    56341 tacgggaaag ataacctgca cgctctgtta cggatactgc accgcgagca tctaataaat
    56401 tgaatgtatg gctacatttc aaaatataat catacgctgg atgaacaaga ttttcatcga
    56461 tacagcgttt agcttctttt tcaaaacgat caaaattgct tagtagcagg tcttggtcgc
    56521 ttacttcaaa agaatattta gaatgttcat attctggttg tttgaagatc tcaccatatt
    56581 tcacgccatc agcccattcc agatcataaa cactttcaac ttcttggata taagaagcaa
    56641 gacgttctag tccataagtg atctcagaag taactggttt acaaggtagt cctccgactt
    56701 gctggaagta cgtgaattgt gtgatctcca tcccatcaag ccatacttcc cagcccacac
    56761 cggcacaacc catcgatggg ttctcccagt tgtcttcaac aaagcgaata tcgtgttcta
    56821 atggatcaat tcctaaaaga cgcaagcttt ctaaataaag ctcttggata ttttcaggtg
    56881 aaggtttcat tacgacttga aattgatgat gctgatacaa acggtttggg ttttctccat
    56941 aacgcccgtc agctggtcgg cgggatggct ctacataagc agcattccat ggttccggtc
    57001 cgattgcccg taagaatgta tatgggctca tcgtacctgc tcctttttct gtatcataag
    57061 cttgcatcag catgcagccg tttgatgacc aaaatttttg taatgttaaa atcatatctt
    57121 ggacggtcaa ttttttactc atctgttttg cccctttcaa tttttaagcg ttgctgtcaa
    57181 taagaataca ggaaagaaaa cgacaaaaag tccctatgtc tgattacaga catagggacg
    57241 aataatttcg cggttccacc ctacttccga ataaagattc ggcagcttca tttatcgtac
    57301 tcgcaagtgc ctcttcaaaa atcgtttggg tccggcttcc actctcccga actcgctaaa
    57361 ccacgtgttt tttactgatc ttggtcaatg tacgtattca ttttgcagtt ttctggtttg
    57421 tataatagat cctctcagtg aacgatctat ttaatctacg gttaataata gacggaagtc
    57481 cctgtatttg tcaaatagtt ttgatttttt tgttgtatct ttcatttatt cttctttttc
    57541 aggtatctct ttttcaggca tatttttctc tggcgtcttt aatacgtgtg cccaagactt
    57601 catttgatca atgaactttt tgctttttag atgaataccg acatattcat catacaactg
    57661 gtcaatgagg tcacggattg cctgcttcgt ttcttctttc aagtggattc cactgatctt
    57721 atcataagaa atagccgaaa acattcgaac gaaataaaca gcgcgaggat ctgcatgata
    57781 acggtgttcg tccattggcc agtgtttctc gcatatcaca ccgccatatt tggaagaata
    57841 gtcaaatttt ccttttgttt ccccgcatac gacacagtgc gtccaaattg gcgcgattcc
    57901 gaagcgttgc agtatttgca cttcaaagat attcgtgatg atttctgcat catctccttg
    57961 gtccatccgc tgcagagctt gttgcgtaaa ttggaataaa tgcgggtcat attgatgatc
    58021 ttcgattgct gcatctacta gatttagcaa atacgtacca taaccgctca aaaagatatc
    58081 ttcttggatg ttccgaaacg catggacgtc tttgacactg cttaaaaacg acaaaccttc
    58141 acttcgaaaa ttaccgatat agactgcttc ggtaaagggg agcaaagccg gagctaatgg
    58201 ctgattttgc cgatggattc ctttgatata aaacatcatt ttgccagaag attccgtaaa
    58261 gattttgact aatttatctt tttctttgta attacggcta gataaaatca agcctttcga
    58321 ttctacaagc tggctcatat tctccctcct aaaaaataaa tctggaaaag cagattctgc
    58381 cgatccagat tatttatgtt tcgatcttcc gctgtttttc tcaacgtacg gatttttatc
    58441 cagtttattt ctatacctaa cctataagaa gtccagaata tcagtactcg tcttttcggt
    58501 agccgaagtc ttgcagatag acttttttgt ctcgccagtc tttttggact ttgacccaaa
    58561 gttctagaaa tactttgtct cctaaaagat tttcgatatc ctttcttgct ttcgttccta
    58621 cttgcttcag catttttccg cctttgccga taatgattcc tttttggcta tctctttcga
    58681 cgatgatcgt ggcctggata tggattttat cattctcgtt tcgcttcatc gaatcaacaa
    58741 cgactgcgac agaatgaggc acttcgtctc gtgttaaaaa caagactttc tcacggatca
    58801 attcagaaac gatgaagtat tcaggatgat cagtcacttg atcatctgga aaatattgtg
    58861 ggccctctgg catttcactg actaatacat ccattaagcg ttcgacattg tttccttctg
    58921 tagcagagat cggaatcact tgtgcaaaag gcatctgcgt cgaataatct tcgatgattc
    58981 ccagcaactc gtctggatgg atcttatcga ttttattgat aatcagataa acaggagaat
    59041 gcacgttttt tagacgttca ataataaaat cgtctccccg gccacgtttt tgatcagcac
    59101 tgatcataaa taagactgca tccacttctt tcaacgcact gtaagctgct tctaccataa
    59161 aatctcctag acgatgcttt ggtttatgga ttcctggtgt atcgataaaa atcagctgag
    59221 cttctggtgt agtatatact ccttggattt tatttctagt tgtctgtgcc ttgtcactca
    59281 taatggcaat tttttgaccc acgattcggt tcaataatgt ggattttcct acattcgggc
    59341 ggccgacgat tgcgacaaac cctgatttat gttctggcat atacgttctc ctttttaatt
    59401 aaacaacaaa tgatatattt tagggacaaa taaaatcaac ccaatgatga cagcaaaaca
    59461 agcggtcact aaaactgctc cagctgccat atctttgatt tttttcccaa tcggatgaaa
    59521 atgaaaatcc gtaaacatgt ccactacatt ttcaaaaaca gtattgatga tctctactat
    59581 ccaaacgaga aaaacagcta aaagcagcca taaccactct atccgatcaa gctggaaaat
    59641 cacgcccata aataaagcaa ggataccgaa cgcaacatgt ttcctcatat tgcgttcttc
    59701 ctcaaaaacg gttttgactc cttggacagc aaattccaca gacatcagga aatgtttgtt
    59761 tttctctacg tttttatctt ttgagtccat aggcatccaa gatctctttc tgtaaaccaa
    59821 acatttcttt ctcatcttct ggtgtcatat ggtcataccc gttgatatgc aaaaatccat
    59881 gtaccgctaa aaagccaagt tcccgatcat atgaatggcc gtaagcttct gcttgttcag
    59941 cagcacgttc aatagagatc atgatgtctc ctagtacacg aggtaatgga ttctctccat
    60001 cttcaaaaat cactgggatt tcgtcttcgc cttcttcttc cagagcaaaa ctgatgacgt
    60061 ctgtcggtgc atcttttcca cggtaatcac gattgattac ttgaattgcc gcattgtcca
    60121 tgaaagtaac agacatttct gtttcctctg gcagctttaa ataagatgct gcaaattgca
    60181 gcaagtcatc gatttctttc attttctctt ctgagacttg gtttgtttca tccataaagg
    60241 taatatccat tatacatcgc ttctttctat tcttcttgta cttcctttat cttctcaact
    60301 tctgttttca ttttaggata tttgatccga gaatggaagg tgctacttaa accgctgatt
    60361 aatgattttt ccacttttcg gatttctttc aaggtcagtc cactatcgtc taattgacca
    60421 tcggaaatac gctcttcgat aagattatgg acaaaacttt cgattttttc gctcgtcgga
    60481 tgatccattg cccgtactgc agcctcacaa ctgtcagcaa tattgacgat ccctgcttca
    60541 cgactttgcg gttttggtcc aggataacgg aattgctctt ctgttacttc cggattgcgt
    60601 tctttcgctt tgatgtagaa ataacgcatt agcgtggttc catgatgctg tttgcaaata
    60661 tcgatcacca tttgcggcat attataatct tccaatattt tggctccatc tgtcacatgt
    60721 ccaaagataa tatgtttact gtcttctggc aataagaaat tgtgcgggtt ttccgctcct
    60781 gaaggcaagt tttcaacgaa aaagctagca tgtttgatct tgccgatatc atgataatag
    60841 caagctactc gagttagcaa agaacgtccg ccgatttctg ctacagcgtt agcacttaga
    60901 ttagctacca tcatactatg atgataagta cctggcgctt cttccagcaa ctgtttcaat
    60961 aaaggatgat ttggattgct gagttcattt aatacaatta cactgtcatc attgaccatc
    61021 aattcaatat atgggtgtag accgatcgtc agcaagaatg agaagagtgc accagtgaac
    61081 ccgcagacga gcattaacca agtcgttgca tcaccaaagc tcattccttg atagacgatc
    61141 aaaatgacat ccatcatcac aggaaaaata atgacccaca tggcagcaga taatccttgt
    61201 tctgagatcc gtttgcgtct gacaatcgtt gccatgagcc cagagaaaac ataagacatc
    61261 aagataatcg ttagaaagtt cgtgccaatc gaatcataaa aaatgaaaag tgcggatact
    61321 gcttggaaaa taccagccat gatccctgct cttcgattca agaaaaagct taaaacaagt
    61381 ggtgcaaaag cagcgggata aaacagcggg atataagtag cttgttccgt ttggaataat
    61441 tggaaaaatt tcatcagcac tatgctgact gacatagctg tcacatagaa aagcacgtat
    61501 tttgttcttt ctcctgcatt ttggaattga agtgaattat aaatcagtac gccgatttga
    61561 agcaaaacag ctaaaaccat ggcaattagc ggaaaaatcg aagttgtttg attagtcagt
    61621 cctagtaatt ccaatttttt catagctgaa gcatcgattt gattaccttc acgaacaatg
    61681 atttctcctt ggaagatcat cactggttgt acagcttctc gtgcggattg tttcaattct
    61741 tctgtctttt tctcattcaa tacgtcattc actacgatac cttgatccac taagtagcga
    61801 atcatttgtt gttgtgctgg tgtgacattc aaatattgga tttgctcttc tgcttcttgt
    61861 ttaaaagctt ccaattcact ttcacgaact tgtttgctca tctgttcgtc aatgagcttc
    61921 agactctcat ccctcacagt atgaatctca gtttcagtca tttcaaatat cgtcgaataa
    61981 aaattgttcg gtagtttttg ataaaacaca acattttctg cattcacatt ttcaaaattt
    62041 ttcttcagcg cggcgatccg ctcttctgta gtaggctttg ggatattttc atcttccttt
    62101 gccttatcaa tcttttcgtc ataagatttg ttgatggcat cattcgtctt atcgatcaat
    62161 tcaaatagtt gcttgatccg attgttctgg tcatctgcaa gatctttttg gtaagtgtat
    62221 tctggagtga ctgcttctgc tgccagtttt cttttttgtt cggtttcttc cgtgttctcg
    62281 atcgttttgt tcgcacggat actttcttct gctacttggc cttctctgaa atcattggcc
    62341 ttttgtttga cactactaaa tgtaacgccg cagataatga taaaaaacaa gaacagcagg
    62401 aaaggcaatg ctgcctttcc aagtttttct tgtagtttct gcagtgtttt attcaacatg
    62461 tgcttatcct cctaagcaaa gcttattctt gatggagatc tgccttttca taagctttga
    62521 tgatttcggc aactacaggg tgccgaacaa cgtcacttgc ttcaaaatta acaaaatcga
    62581 ttttcttgat ttgctttaat gttcgttctg catgaacaag accacttgtc gtccctcgag
    62641 gcaagtctat ctgacttgta tccccattga caatcatttt tgattgataa ccgagacggg
    62701 tcaagaacat tttcatctga gcgactgtcg tgttttgtgc ttcgtccaag ataacgaatg
    62761 catcatccaa tgttcgcccc cgcatgtaag ctaaaggtgc gatttcgatt acgcctcgtt
    62821 ccatcaatcg gttcgtatga tccaatccaa aaatttggta taaagcatca taaacaggcc
    62881 gcagataagg atccactttt tcttttagat ccccgggaag aaagcctaga ttttcacctg
    62941 cttccacagc aggccgcgtc aaaatgattt tttgcacttc accttttttc aaggcagcga
    63001 ttgctaatac tactgcaaga aaagtttttc ctgtcccggc tggtcctacg ccaaatacga
    63061 tatcatgttt ggctaccgat tcgacatatt tcttttggcc gctgtttttt acccgtatag
    63121 gttttccatt acggtctttg acgatctctt cctcatacat ctcaacaaaa taatctaatg
    63181 tacctttttg ccccattttc aatgccgtca caacatcggg cgtacttacg tggattcctc
    63241 gtttgatcaa ttcctgtaat gtccgaatga ctgaggcagc caaggaaatc tgggattgct
    63301 caccaatgat ctgaatgatt tctccacgtg tatggatggt tgtttccgtt gtttcctcaa
    63361 tcagttttat atgcttgtcg tgtgcaccta aaagcatgct gacatcatca gcagccgtca
    63421 atctaatctc taaagaacta gactcttccg tcaaaaatag acatcccctt tttttcgatt
    63481 aattctttcc tattttacca tactcagaag aaactatata gcaaataaga aaaggttcta
    63541 aaagagttgc ttaaccataa gtaccaagaa acgttaaaaa actagccgct tccattctct
    63601 aaaggtctcg tttgaataaa aaaagctgat catgtaagct atgcataaga tagaggacaa
    63661 gtattccgtc taacttagca agtattctct gggtattttt cttgtttcaa aaaaagaaaa
    63721 caaaatattt gaaatattct tgcatttcaa aaaaaacagg tgtattataa cgtcaacaaa
    63781 taaatataca gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta ttcccagtga
    63841 gtcatgtaag tgagaaatga caataaatcg aatagacgaa catcatttcc gagtcaatgt
    63901 cgaaaacgta gatcattgtg gctgcctcca ttatcaggct agcggataac tttatcgaaa
    63961 agcgtccgtg aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt ctagaatcta
    64021 gagccctttt cccaagtgga aaagggcttt ttttatattt taaggtggtg gttttcatgg
    64081 aatctgatat tagtggtatt tctagtttct gcaacgttta ttttgttact caaaatgata
    64141 attattggag gaaaaattta tggaagaaac aaaaacttat tcatggaagc aattattgat
    64201 ggtcagttca cttatcttcg ggatgttctt cgggtcaggt aatctgatct ttcctgtaca
    64261 cttaggtcaa atggctggat caaactggat cagcgctggt gtaggatttg ccatctcagg
    64321 cgctcttttc ccattattag ctatcttagc tgtagtagtg acaaaaagtg atggtctgta
    64381 tgacttagct aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc ttgttcattt
    64441 aacgatcgga ccattctttg gtacaccgcg gacagcagca actgcttttg aaatggctgc
    64501 taaacccttt ttgcctgaaa aatatgattc attaggtatg tttttattct ctgctctttt
    64561 ctttttactt gcttatttcc ttactgtaca tccaacacgt ttggtcaaat atgtcggaaa
    64621 gtatttaaac tccttgtttc ttgcattatt agctatcatt tttgtcgttt ctttattcca
    64681 acccatgggg aatctaaacc aatctgctgc agattcttat cagacgaacg ctttgacaaa
    64741 tggcgtttta gaaggataca acacggttga tgcagtagct ttacttgctt taagtgtcac
    64801 ttttgtccat gcagttcgtg atcttggttt taaagataaa aaagtcacag aattaacagc
    64861 aaaagctggt agcctgagcg ttgcgttaga agtcatgatt tattttggtc tggtccttct
    64921 cggtgcgatg agtttgaata agatgtcttt atcagaaaat ggcggaactg cactttctca
    64981 gatcactaat ttttatttag gtaacttcgg tgctagcttc ttaggggtaa tggtcacatt
    65041 aggtgtcttc actactgcta tgggactcgt tgtttctttt gcacaagatt tccataaact
    65101 gttccctaaa gtcagttata tgacatggct gcggttaacg acttttgtct cttttgtcgt
    65161 tgcgaatgcc ggattggata atatcatcca atggtcttta ccagtattga tgcttttgta
    65221 tccattgtca cttgcgttaa tcttactttc cttaacagca aaattcttcc aaaagagtcc
    65281 atttgtctat caagtaacga tgttcttttc tgccgttcca gccgtattgg atatgttggc
    65341 aaattcgcct gcattagtga gtcagcaaac tgtcgtagca agcttactag gattttatca
    65401 tcattatgtt ccttttgctg cattaggtct tggctgggtc gtcccaacat tgcttggtta
    65461 cgctggcagc ttgctctttt attatgtata tcgcgtatca ggatataaac aagaagcaag
    65521 tgagttacca gaagaataac caaatcaaac acaatttaac ataagagata ttaaacagga
    65581 aaaaaacagc tagaagaaa
//
LOCUS       DAPBBV010000011        61535 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.011, whole genome shotgun sequence.
ACCESSION   DAPBBV010000011 DAPBBV010000000
VERSION     DAPBBV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 61535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.011"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(59..187)
                     /locus_tag="RD486_000897"
     CDS             complement(59..187)
                     /locus_tag="RD486_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDT7662648.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="RD486_000898"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="RD486_000898"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDT7662649.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="RD486_000899"
     CDS             complement(1674..2729)
                     /locus_tag="RD486_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDT7662650.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="RD486_000900"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="RD486_000900"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HDT7662651.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="RD486_000901"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="RD486_000901"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HDT7662652.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="RD486_000902"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="RD486_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HDT7662653.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="RD486_000903"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="RD486_000903"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDT7662654.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="RD486_000904"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="RD486_000904"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HDT7662655.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="RD486_000905"
     CDS             10491..12050
                     /locus_tag="RD486_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HDT7662656.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="RD486_000906"
     CDS             complement(12161..14092)
                     /locus_tag="RD486_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7662657.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="RD486_000907"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="RD486_000907"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDT7662658.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="RD486_000908"
     CDS             complement(15021..15773)
                     /locus_tag="RD486_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7662659.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="RD486_000909"
     CDS             complement(15932..16141)
                     /locus_tag="RD486_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662660.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="RD486_000910"
     CDS             complement(16152..17480)
                     /locus_tag="RD486_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662661.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="RD486_000911"
     CDS             17616..17771
                     /locus_tag="RD486_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662662.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /locus_tag="RD486_000912"
     CDS             complement(17845..18432)
                     /locus_tag="RD486_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDT7662663.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="RD486_000913"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="RD486_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDT7662664.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="RD486_000914"
     CDS             complement(20012..21301)
                     /locus_tag="RD486_000914"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDT7662665.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="RD486_000915"
     CDS             complement(21455..22387)
                     /locus_tag="RD486_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662666.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="RD486_000916"
     CDS             complement(22544..23203)
                     /locus_tag="RD486_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDT7662667.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="RD486_000917"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="RD486_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDT7662668.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGASGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="RD486_000918"
     CDS             complement(24244..24534)
                     /locus_tag="RD486_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662669.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="RD486_000919"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="RD486_000919"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDT7662670.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="RD486_000920"
     CDS             complement(26821..28176)
                     /locus_tag="RD486_000920"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDT7662671.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="RD486_000921"
     CDS             complement(28200..29369)
                     /locus_tag="RD486_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662672.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="RD486_000922"
     CDS             complement(29366..30253)
                     /locus_tag="RD486_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDT7662673.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="RD486_000923"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="RD486_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDT7662674.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="RD486_000924"
     CDS             34320..34841
                     /locus_tag="RD486_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDT7662675.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="RD486_000925"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="RD486_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="RD486_000926"
     CDS             complement(36284..36940)
                     /locus_tag="RD486_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662676.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="RD486_000927"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="RD486_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDT7662677.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="RD486_000928"
     CDS             complement(38477..39475)
                     /locus_tag="RD486_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDT7662678.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="RD486_000929"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="RD486_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDT7662679.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="RD486_000930"
     CDS             complement(40491..41222)
                     /locus_tag="RD486_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HDT7662680.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="RD486_000931"
     CDS             complement(41226..42491)
                     /locus_tag="RD486_000931"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HDT7662681.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="RD486_000932"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="RD486_000932"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDT7662682.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTISQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="RD486_000933"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="RD486_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDT7662683.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="RD486_000934"
     CDS             47833..49335
                     /locus_tag="RD486_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HDT7662684.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="RD486_000935"
     CDS             49337..50074
                     /locus_tag="RD486_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7662685.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="RD486_000936"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="RD486_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDT7662686.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="RD486_000937"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="RD486_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDT7662687.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="RD486_000938"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="RD486_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDT7662688.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="RD486_000939"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="RD486_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HDT7662689.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="RD486_000940"
     CDS             complement(55574..56740)
                     /locus_tag="RD486_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDT7662690.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGNRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="RD486_000941"
     CDS             complement(56756..56983)
                     /locus_tag="RD486_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDT7662691.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57370..57626)
                     /locus_tag="RD486_000942"
                     /pseudo
     CDS             complement(57370..57626)
                     /locus_tag="RD486_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(57969..58992)
                     /locus_tag="RD486_000943"
                     /pseudo
     CDS             complement(57969..58992)
                     /locus_tag="RD486_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(59476..59637)
                     /locus_tag="RD486_000944"
     CDS             complement(59476..59637)
                     /locus_tag="RD486_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662692.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="RD486_000945"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="RD486_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61417
                     /locus_tag="RD486_000946"
     CDS             60827..61417
                     /locus_tag="RD486_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDT7662693.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
BASE COUNT        17074 a        13213 c        10647 g        20601 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagcc cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaat tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attgggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atttccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt catag
//
LOCUS       DAPBBV010000012        59617 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.012, whole genome shotgun sequence.
ACCESSION   DAPBBV010000012 DAPBBV010000000
VERSION     DAPBBV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.012"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            188..418
                     /locus_tag="RD486_000947"
     CDS             188..418
                     /locus_tag="RD486_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HDT7662694.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            515..1816
                     /gene="murA"
                     /locus_tag="RD486_000948"
     CDS             515..1816
                     /gene="murA"
                     /locus_tag="RD486_000948"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDT7662695.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1829..2005
                     /locus_tag="RD486_000949"
     CDS             1829..2005
                     /locus_tag="RD486_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDT7662696.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2140..2436
                     /gene="yidD"
                     /locus_tag="RD486_000950"
     CDS             2140..2436
                     /gene="yidD"
                     /locus_tag="RD486_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDT7662697.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2621..3088
                     /locus_tag="RD486_000951"
     CDS             2621..3088
                     /locus_tag="RD486_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662698.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3173..4057
                     /locus_tag="RD486_000952"
     CDS             3173..4057
                     /locus_tag="RD486_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7662699.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4171..4407
                     /locus_tag="RD486_000953"
     CDS             4171..4407
                     /locus_tag="RD486_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HDT7662700.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4495..4575
                     /locus_tag="RD486_000954"
     tRNA            4495..4575
                     /locus_tag="RD486_000954"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4529..4531,aa:Tyr,seq:gta)
     gene            4582..4653
                     /locus_tag="RD486_000955"
     tRNA            4582..4653
                     /locus_tag="RD486_000955"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4614..4616,aa:Gln,seq:ttg)
     gene            4778..4948
                     /locus_tag="RD486_000956"
     CDS             4778..4948
                     /locus_tag="RD486_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662701.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5168..5875
                     /locus_tag="RD486_000957"
     CDS             5168..5875
                     /locus_tag="RD486_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7662702.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5934..6578)
                     /locus_tag="RD486_000958"
     CDS             complement(5934..6578)
                     /locus_tag="RD486_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDT7662703.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6704..6991
                     /locus_tag="RD486_000959"
     CDS             6704..6991
                     /locus_tag="RD486_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662704.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7099..7419
                     /locus_tag="RD486_000960"
     CDS             7099..7419
                     /locus_tag="RD486_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7662705.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7500..8813
                     /locus_tag="RD486_000961"
     CDS             7500..8813
                     /locus_tag="RD486_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDT7662706.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8810..9529
                     /locus_tag="RD486_000962"
     CDS             8810..9529
                     /locus_tag="RD486_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDT7662707.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9657..10208
                     /gene="raiA"
                     /locus_tag="RD486_000963"
     CDS             9657..10208
                     /gene="raiA"
                     /locus_tag="RD486_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDT7662708.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10430..12964
                     /gene="secA"
                     /locus_tag="RD486_000964"
     CDS             10430..12964
                     /gene="secA"
                     /locus_tag="RD486_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDT7662709.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13090..14191
                     /gene="prfB"
                     /locus_tag="RD486_000965"
     CDS             join(13090..13161,13163..14191)
                     /gene="prfB"
                     /locus_tag="RD486_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDT7662710.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14296..14982
                     /gene="ftsE"
                     /locus_tag="RD486_000966"
     CDS             14296..14982
                     /gene="ftsE"
                     /locus_tag="RD486_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HDT7662711.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14966..15859
                     /locus_tag="RD486_000967"
     CDS             14966..15859
                     /locus_tag="RD486_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662712.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            16011..17459
                     /gene="cls"
                     /locus_tag="RD486_000968"
     CDS             16011..17459
                     /gene="cls"
                     /locus_tag="RD486_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDT7662713.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQISNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17796..18653
                     /locus_tag="RD486_000969"
     CDS             17796..18653
                     /locus_tag="RD486_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDT7662714.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18768..19688
                     /gene="pstC"
                     /locus_tag="RD486_000970"
     CDS             18768..19688
                     /gene="pstC"
                     /locus_tag="RD486_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDT7662715.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19688..20572
                     /gene="pstA"
                     /locus_tag="RD486_000971"
     CDS             19688..20572
                     /gene="pstA"
                     /locus_tag="RD486_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDT7662716.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVSEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20587..21393
                     /gene="pstB"
                     /locus_tag="RD486_000972"
     CDS             20587..21393
                     /gene="pstB"
                     /locus_tag="RD486_000972"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDT7662717.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21409..22167
                     /locus_tag="RD486_000973"
     CDS             21409..22167
                     /locus_tag="RD486_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDT7662718.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKNKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22180..22857
                     /gene="phoU"
                     /locus_tag="RD486_000974"
     CDS             22180..22857
                     /gene="phoU"
                     /locus_tag="RD486_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDT7662719.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23094..24125
                     /locus_tag="RD486_000975"
     CDS             23094..24125
                     /locus_tag="RD486_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDT7662720.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTNQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKHGLFALGSLIINIVLLLLLLLIFTKIEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNLWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            24122..24889
                     /locus_tag="RD486_000976"
     CDS             24122..24889
                     /locus_tag="RD486_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDT7662721.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24989..26557
                     /gene="liaX"
                     /locus_tag="RD486_000977"
     CDS             24989..26557
                     /gene="liaX"
                     /locus_tag="RD486_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HDT7662722.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26854..27174
                     /locus_tag="RD486_000978"
     CDS             26854..27174
                     /locus_tag="RD486_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HDT7662723.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27174..27524
                     /locus_tag="RD486_000979"
     CDS             27174..27524
                     /locus_tag="RD486_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDT7662724.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27691..28629
                     /locus_tag="RD486_000980"
     CDS             27691..28629
                     /locus_tag="RD486_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDT7662725.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28644..29474
                     /locus_tag="RD486_000981"
     CDS             28644..29474
                     /locus_tag="RD486_000981"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDT7662726.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29518..30543
                     /locus_tag="RD486_000982"
     CDS             29518..30543
                     /locus_tag="RD486_000982"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDT7662727.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30558..31496
                     /gene="galU"
                     /locus_tag="RD486_000983"
     CDS             30558..31496
                     /gene="galU"
                     /locus_tag="RD486_000983"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDT7662728.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31621..32061
                     /locus_tag="RD486_000984"
     CDS             31621..32061
                     /locus_tag="RD486_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDT7662729.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            32064..32666
                     /locus_tag="RD486_000985"
     CDS             32064..32666
                     /locus_tag="RD486_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7662730.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32725..33831)
                     /locus_tag="RD486_000986"
     CDS             complement(32725..33831)
                     /locus_tag="RD486_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDT7662731.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            34041..35042
                     /gene="ccpA"
                     /locus_tag="RD486_000987"
     CDS             34041..35042
                     /gene="ccpA"
                     /locus_tag="RD486_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HDT7662732.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(35379..37724)
                     /locus_tag="RD486_000988"
     CDS             complement(35379..37724)
                     /locus_tag="RD486_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDT7662733.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            38003..38905
                     /locus_tag="RD486_000989"
     CDS             38003..38905
                     /locus_tag="RD486_000989"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDT7662734.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            39118..40893
                     /locus_tag="RD486_000990"
     CDS             39118..40893
                     /locus_tag="RD486_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDT7662735.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(40959..42545)
                     /locus_tag="RD486_000991"
     CDS             complement(40959..42545)
                     /locus_tag="RD486_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDT7662736.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            42796..43020
                     /locus_tag="RD486_000992"
     CDS             42796..43020
                     /locus_tag="RD486_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HDT7662737.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            43162..44913
                     /locus_tag="RD486_000993"
     CDS             43162..44913
                     /locus_tag="RD486_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7662738.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            44913..46697
                     /locus_tag="RD486_000994"
     CDS             44913..46697
                     /locus_tag="RD486_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662739.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            47023..47874
                     /locus_tag="RD486_000995"
     CDS             47023..47874
                     /locus_tag="RD486_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7662740.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     EKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            47928..49679
                     /locus_tag="RD486_000996"
     CDS             47928..49679
                     /locus_tag="RD486_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7662741.1"
                     /translation="MAKPSTNKLEGIEMGKYQELARKIVENVGGKENINGLTHCITRL
                     RFKLKNEEKANDEILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAV
                     STEKMRPFDMLIDGISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNI
                     GDSVFQFMPVIIGLTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSG
                     TIFEAPIYQTVFGIPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFF
                     TVLITMPLGFLLVGPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWA
                     IVPMGLMQFSVNGWQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVG
                     ITEPAIYGFTLPRKKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGD
                     LTDVINVLIGIAIAMVVSFTLTFFFWKDEAGETDDIQKKSGKEIVKTPIQGQIAPLNA
                     AKDAAFAQGTLGRGILIYPEKGEVRAPFDGTVMTLFPTKQAIGMVSETGLELLIHVGL
                     DTVQLEGKYFESLVQQG"
     gene            49683..49853
                     /locus_tag="RD486_000997"
     CDS             49683..49853
                     /locus_tag="RD486_000997"
                     /inference="COORDINATES: protein motif:HMM:NF012578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7662742.1"
                     /translation="MKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGET
                     VGPDDALITALT"
     gene            complement(49893..50795)
                     /locus_tag="RD486_000998"
     CDS             complement(49893..50795)
                     /locus_tag="RD486_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7662743.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            51026..52429
                     /locus_tag="RD486_000999"
     CDS             51026..52429
                     /locus_tag="RD486_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7662744.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            52429..53862
                     /locus_tag="RD486_001000"
     CDS             52429..53862
                     /locus_tag="RD486_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7662745.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYASRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            54007..54933
                     /gene="trxB"
                     /locus_tag="RD486_001001"
     CDS             54007..54933
                     /gene="trxB"
                     /locus_tag="RD486_001001"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDT7662746.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            55147..56874
                     /locus_tag="RD486_001002"
     CDS             55147..56874
                     /locus_tag="RD486_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDT7662747.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            56889..57239
                     /locus_tag="RD486_001003"
     CDS             56889..57239
                     /locus_tag="RD486_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDT7662748.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(57331..58191)
                     /locus_tag="RD486_001004"
     CDS             complement(57331..58191)
                     /locus_tag="RD486_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDT7662749.1"
                     /translation="MTSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            58283..58711
                     /locus_tag="RD486_001005"
     CDS             58283..58711
                     /locus_tag="RD486_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7662750.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGKIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            58873..59049
                     /locus_tag="RD486_001006"
     CDS             58873..59049
                     /locus_tag="RD486_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDT7662751.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            59076..59522
                     /locus_tag="RD486_001007"
     CDS             59076..59522
                     /locus_tag="RD486_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDT7662752.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT        19420 a        10336 c        12779 g        17082 t
ORIGIN      
        1 tttggaataa gggactgcga caagactttt gtctcagtcc ctttttttgc atatttttag
       61 catttatttc ctaaaaaatg taaggggatt cctatatttt taagtatact tgtttttcct
      121 tttatacatt ttatggtatt atcattttat tagttattat aaaacaatcg ttagaaagga
      181 cgtcattatg caagtatacg gaattgatgc ggtgcttcga atcgtgagtc atttggcgtt
      241 tatctactta gccttctggt ctttacgttc gttacgcatt gaaacttttt tcagaccaat
      301 gcataatacg caaattagaa tggcaatcgt acttttttca atttttttag ggtacactgc
      361 aagtaatttt ttcttagaag ttatcgcttt atgccgaaat cttttcgtta gcctgtaaat
      421 tttaaaaaaa ggtactattt taaaagcaag gatgttataa tagaaaagat tttgagtaag
      481 tgtatgctca ttggaatttt ttggagggaa caacatggaa gagatcatcg taagaggtgg
      541 caatcaatta aatggaacag taagaattga aggagctaaa aatgctgttt tgcctatttt
      601 agctgctagt ttgttagcag aagaaggtat tacgacatta gacaacgttc cgattctttc
      661 tgatgtcttc actatgaatc aagtgattcg tcacttaaac gtagatgtag attttgatga
      721 acaaaagaat caagtaacaa tcgacgcttc aagacaatta gaaatcgaag cgccttatga
      781 gtatgttagt caaatgcgtg cttcaatcgt tgtgatgggt ccgctacttg ccagaaatgg
      841 acatgcaaaa gtagctatgc ctggtggatg tgcgattggt aaacgaccaa tcgatttgca
      901 tttaaaagga tttcaagctt taggagcaaa aattattcaa aaaaacggct atatcgaagc
      961 aattgcggat gaattgatcg gtaacacgat ttatttagat ttccctagtg taggtgctac
     1021 tcaaaatatc atgatggctg ccgtaaaagc aaaaggaaca accatcattg aaaacgtagc
     1081 tcgcgaacca gaaatcgttg atttagcaaa cattttgaat aaaatgggcg ctcaagtcta
     1141 tggagctggt actgaaacaa tgcgtattga aggcgtggat catttacatg cagtcaacca
     1201 ctcaatcgta caagatcgta tcgaagcagg tacctttatg gttgctgctg caatgacaca
     1261 aggcaatgtg ctgattgcag atgctatctc tgaacataac cgcccattga tttctaaatt
     1321 gatcgaaatg ggtgcagaaa tcattgaaga agaaggcgga gtccgtgtca tcggaccaaa
     1381 acatatctta cctacagatg taaaaacgat gcctcatcct ggtttcccta cagatatgca
     1441 agctcaaatg acagctatcc aattagttgc agaaggtaca agtgtagtga ctgaaacagt
     1501 gtttgaaaat cgtttccaac atttagaaga gatgcgccgt atgaacgctc atgtcaaaat
     1561 cgacggaaat gtagcaatca tggatggaaa ccatgaattg caaggtgcag aagtatatgc
     1621 aacagacttg cgggcagcag cagcattagt tttagctggc ttgaaagcaa atggaatcac
     1681 acgtgtgcgt aacttgaatt atctagaccg tggatattat aatttccata tcaaactaca
     1741 gcaattaggt gcagacgttg aacgtgtaga catggatcaa acttctgctg aaaaaacagc
     1801 acaaacgatt gcttaaggaa gtggctgaat gagtaaccaa cgatatatct tattaacttt
     1861 gataaagatt ttaatggtga tcttattgct tatccttctt tttgtggccg gaacgatgat
     1921 cggatatggt gtcatcggtg gcggcaatcc atttaaagta tttcagccaa gtttgtggat
     1981 tcatattcga gacttttttc attgataaat aagaatcaca gtggttctag tcgatatgaa
     2041 gtgagccatg aagcagaaca tgataaaaga aaacagaagg gaacgttgac gttagtcgcg
     2101 atcccttttt ttagtaaaag aaaagaagga atctaattga tgaagaagat attgatttat
     2161 ttagttagag gatatcagcg ctttatttcg cctgcatttc cacctagctg ccgttattac
     2221 ccaacctgtt ccaattatat gataaaagca attcaaaccc atggcgcgct aaaagggacg
     2281 gtaatgggga ctgcacggat cttacgctgt catccttttg tcaaaggcgg tatcgattat
     2341 gtaccattga cattccgatt aacgcgaaat aagaaagata aaaaagaacc agattataaa
     2401 aaggttgtga aaaatacggg tagcactgag cgataaagaa acaatttgga aaatagcttc
     2461 ttatattttg caaaattgtg agttattgcc gaagtgttgg attttgaaca ccgtcaaaaa
     2521 aaaggttgtg aaaaatacgg ctagcactga gcgataaaga aaaagaggaa atttattgtc
     2581 aaagtaacaa ctccgcaact acttatatgg gggacaaaaa atgatcgaag aactaaacaa
     2641 gaaagattta ccatggtcct tgttattaga tgcagatcct gataaagaaa aagttcaagt
     2701 atatgtttcc agagggagtg gctggatatg gaaagaaaaa gaaaaaacaa taggtgtact
     2761 gatctatgtg gcaagggaaa aagaatacga aatcgtcaat gtagcagtaa ccccaacgta
     2821 tcaaggaaag gggattggcg gaaaattact tgagacagct tttcagaagc tttcacaact
     2881 cgcttccagt caaactcaga tcatcatacg aaccggcagt actagcagtg cggcgttaca
     2941 tctctatcaa aaaatgggct atgtggagat tggtcgagtc aaagactatt ttatccatca
     3001 ttactctgag cccatttttg aaaatggaga tcaattaagg gatcaagtga ttttagcaat
     3061 tcacttacct aaaaatagct ttaactaata aaatttcaat tcaagaaaat gctttcaaat
     3121 gctaaataga tacattacaa tagctttagc aaacaaaaag gagaatattt ttatgggaat
     3181 attagttttt gattttggtg gatcggctgt caaatatggt tgttgggatg gcaaagagat
     3241 taaaggtaag ggacaatttg caacgcctga atcttgggaa gaaatgaaag cgcaattatt
     3301 tcaagtttat aaaaaaatac tcgtttcttt tgaagtcgaa ggaattggaa tcagctctcc
     3361 tggagtagtg aataatgaga aacaggtgat tgagggaatc agtgcgattc cttatattca
     3421 tggatttaat attttccgag atttggaaac tctgtttcaa cttccagtaa cgattgaaaa
     3481 tgacgccaac tgtgccggaa tggctgaatt ttatgaaggt gctgcccgcg attatcaaga
     3541 tgttgctttt gttgtggcag gaactgggat tggcggggcg ttgttcacga aaggacaaat
     3601 caataaaggg gcacatcttt acggtggaga atttgggttg atgttcttaa atggcgataa
     3661 gacattcagt aaacttggta cagcggtaca gatggcttgg cgttattgtg aacgcaaagg
     3721 tctcgataaa aatgcttata ccggaaaaga tgtctttgaa ttagcagaaa ctggagatgc
     3781 aatagcaaaa gaagaagttg agagttttta tacgtatctt acaaagggat tattcagtat
     3841 tcaattttcg tttgatccag aagtgatcgt attaggcggc ggggtttctg caaaagaagg
     3901 gctcattgat gagatcaaaa gccgaatgaa gaagctgaca gaacaattcg atctgcatga
     3961 tttcgaaccg cagattttat tatgtgaata cagaaacgat gctaatcttg taggtgcagc
     4021 agcaaactat ctcgctgtac gtcaagggga gaattaagag ctttagagaa ggtgcagctt
     4081 gcataaaaga agtgaatgaa atgaatagga gatttttacc taaggaatgt tttatttgct
     4141 gcagtatgat aaaatatctg agaggtgaaa atgatgtcaa aaaaaaataa agatattgaa
     4201 gtgcgtatag aagaagtgaa aaaagatatc aaaggtaaga attatgaagt cactcagtta
     4261 tttataggga aaaaaatgat tggtgagatc ttagcctatg gaccaaaaga atatgaaatt
     4321 ttctttggtg aagaagattt tggaaaagaa aaaagtcttg aaaatgcgat agaaacagtg
     4381 attcgacact ggaatctgca cgaataaaaa aatatcaaaa aaactttcaa taaagggttg
     4441 caaaaatctg gaaaattagg tattataact aagtcaggtt gatacaaacc tttcggagga
     4501 gtagcgaagt ggctaaacgc gacggactgt aaatccgttc cttagggttc agtggttcga
     4561 atccactctc ctccatttca ttggggtata gccaagcggt aaggcaaggg actttgactc
     4621 cctcatgcgt tggttcgaat ccagctaccc cagtatacca caatcgtaag ctctcgttag
     4681 ttcgagagct cttttttttg ctttgctacc ttgttccttg aagattctgc tgatttaaga
     4741 tagagttaag ttaactacaa gaattggagg gatccacatg aaatggaaag aaaaagtaga
     4801 cgaagcagct gaaaagttat atgatttggt caaatcagaa aaatacaata ttgaagtgaa
     4861 tattccgaaa aaaggcggaa aagcggtccg ggtaaaatca aaacgcccaa cgaatcatac
     4921 aaaaaaatgg atggctaaaa accgctaata ataacaaaag atccataagt cggcattttc
     4981 atcgatttta gggtcttttg ttattttcta ggttggacat atctaaaaaa ttgtttctga
     5041 caataggagt aggaagaacg atgtgtgtct aaatcctctg ttgatggata gaaaccttta
     5101 tctttttcag ttgtgaatca ggtatatacc agttataata gaagaaacga aaggacgggt
     5161 gtacgttatg tcgaatcaat tacctgtata tatacagatt catgaccaat taaaaaatga
     5221 aatcgaacaa ggtatatgga aagtcggaga ccgtcttcct tcagaaagag aattagcagt
     5281 gaaattcaat gtcagccgta tgacgttgag acaagcaatt caaaacttgg cagatgaagg
     5341 aatcttagaa agaaagatcg gttcgggtac atatgttgca cgagaaaaag tacaagaaaa
     5401 aatgtctggt gcaacaagtt ttacagaaat tatggaatca caaaatcgag taccgtctag
     5461 tcggacaatc tcttatttct tgacttcgcc aagctcaagt gaaatggaaa aactaaactt
     5521 gagtaaagat gacacgatct tgcgaatgga acgtattcgt ttcgcagatg atgtccctat
     5581 ttgttttgaa gttgccagtg tgccacaaaa gctgatcgat ggctacagca aagcagagat
     5641 tactgaatcg ttgtatcgca cgctagaaga aaaaggcggg aaaaagatcg gtccagcgaa
     5701 tcaaacgatt actgctgtgt tggcttctga gaaaattgct gactatttag aggtaaaacg
     5761 aggagatgca gttcttcgtt tgcgccagat ttcttatttt gaagacggta cgccgtttga
     5821 gtatgtgcgt acgcaatacg taggaaatcg ttttgagttt tatttggaaa aataaaaaac
     5881 aggtgatccc tgattccgta ttagaaataa aagagaatca gaatcacctg tttttatata
     5941 tgatcagtta ccagttgctc gtgataagaa acaggaccct cttcaaattg gacttgtccg
     6001 ttcagcagct caatgatgga ttctttaaag tggtcagcac ttttttcatc tacagcacag
     6061 atgacgctaa cttgatcagt atattggatt tcttttataa aaaaatgttg gagttcaaga
     6121 taattctgta attttcctag ttgcggatac gtgatcatca cagagatctc ctgttgcaag
     6181 gtaccttcta cgattccaat gtcagacaat gcttgagaga ccgcatgagt gtatgctcgt
     6241 attaatccgc ctgtgccgag tttcgttcct ccaaaatatc gagtgactac tgcagctaca
     6301 ttgatcagtt gatttttttt gaggacttcc aacatcggta tgcccgccgt tccacttggt
     6361 tctccatcat cgctgcttcg ctggatttca tttttttctc caatgatgaa ggcgctgcag
     6421 ttatggttcg ctttccaatg ttcttttttt atttcttgaa tgaaactttt tgcttcgtcc
     6481 tctgattcta ttcgtctaag agaacagata aagcgtgatt ttttgatctc gatctcactt
     6541 tgtccatttt cttttattgt acgatagcgc tcgatcatct tgtcacctct tttttcattt
     6601 tctttattca gtataaataa agttctaggt tgtttcaaca ctgtaacggt tgcgcaattg
     6661 ctgtagtatg cgataataaa gacaaaggca ggtggatctg gggatgcagg aacgaatgaa
     6721 aaagtacgat gcaattacgc attatttgaa gaacaatggc ggctctcaag taacgttgac
     6781 ctttacccaa tttgacgaac tgctgtttcc cagtaacgga cttcccaaaa cagcaaggga
     6841 aagtacagat tggtgggcaa atgattataa acaccctgaa aaaggtgcct atggctggat
     6901 aaatgcaggc tatgaagtag ttgtcatcaa tttggacaaa gaatatgtcg tgttcaataa
     6961 attagtgaaa tctagttggc tatttgatta aataaaccgc gtttagaaaa cgttgacaaa
     7021 tttctttctt tttatataat agagtaacag acgcgaagaa aacgtttgcg tagtttgttt
     7081 taaaaaggag agaaaagtat ggctaaaaaa acaatcatgc ttgtatgttc ggctggtatg
     7141 agcacaagtt tactagtaac aaaaatgcaa aaagctgctg aagcaaaagg aatcgactct
     7201 gatattttcg ctgtgtccgc ttctgacgca gataacaatc ttgcaaataa agacgtggat
     7261 gtgttgttat taggcccaca agttcgcttt atgaaagctg attttgagaa acgtctggaa
     7321 ccaaaaggca ttcctttaga tgtcatcaat atggctgatt atggtatgat gaatggcgaa
     7381 aaagtgttag atcaagcaat cacgctcata ggtgaataaa tagaacagta taactatcga
     7441 acaagcgatc caaaaaatag atcgcttgtt ttttcgtata tttttttagg gcgaataata
     7501 tgaatcattt ttggggtaga aggcttctga cgagagatat taaagcaata gactgtgagg
     7561 aggtaaattt accaaattat gagaagatcg cagcagtgga acgtttgagc aactggattc
     7621 tttgtcatcg ctgtggaatg agaacgtccg tcattgatgg acagcttgca gattacggtt
     7681 atttttgtac acattgtcta tatttagggc gatgcgacac tcaacaagat ttatatttgt
     7741 ttgatcagcc tgaagcaaaa cctcgagaag tcgtcttttt ttggacagga cagcttactg
     7801 aaaaacaaac ggaaatctca aagagaatac tttgccattc agaaaaaaga catcatctta
     7861 tttgggctgt aacaggtgca gggaaaacag agatgcttta tcctatttta gtggaaactt
     7921 taaaagctgg aggaagagta gcgatttgta caccgcgagt cgatgtttgt aatgaattgt
     7981 ttttacgcta tcgttatgtt tttccagaag aaaaaatcac gttgctccat gggaatacag
     8041 caacggctta tacctttact tcttttgtta tctgtacgat tcatcagcta taccgttttt
     8101 atcggtcctt tgatttaata gtgatcgatg agatcgatgc gtttccttat aacggggatg
     8161 caggattagc tcatgctgtg caaacagcga ttaaaccaga cggacgattc atctacttaa
     8221 gtgccacacc tgataaaaag ttactaaagg agatcaagca gacgtttgac atccacaaac
     8281 ttgctttacg ctttcatcgg cgtttgcttc ctgaacccgt cttggttttc atgaataatt
     8341 ggcgacaaaa atgcaagaac aagaagaaga taaaatcttt ggtgcggatc attcatcaat
     8401 taattaaaga aaaccatatc cttttatttt gtccaagtat cacgatgatg catcgtttga
     8461 aagccacact tcaagaggct cttccgagat atgagatcac agatgtttct tcaagagaca
     8521 atcagcgggc ggaaaaagtc cagaaaatgc gagaagcaaa atatgacata ctgttaacca
     8581 cgatgatcct tgaacgtgga gtcacatttg aaagaatatc cgttatcgtt ttaggagcgg
     8641 atcatccggt ttttactaaa tcttctttgg tacaaatcgc aggaagagcc gatcgtaaag
     8701 ggccttatac gaacagtcaa gtatattttt tctatgaaga aaaaactgca gctattcgaa
     8761 aagcttgtca ggaaatcaaa gaaatgaatg aagaagggaa gaagatactg tgaggtgcag
     8821 ttgctgcagt aaagatatcg tccaaaattt aacattcagc gagattattg gtgtttcgaa
     8881 atacagatta cctcagactt gttcagtttg tcgcgcacaa tttcatttat tggaaacaag
     8941 aggctgttct ggctgtcaaa aaccaatcca tttcaatcta gagagtacga aaaagaaagt
     9001 aaattctatc cccgtttact gcagtgactg tcaagaatgg aagaagaaat atccgaccta
     9061 tgattttcag caccgtgcct tttttgtgta cgatgaaaat atgaaggcct ggctcaatca
     9121 atacaagttt atgggagata tccgactagc aggcaccttt gcatataaat ggacgcagat
     9181 aaaaaaagaa tacccgacat acatctattg tccaatacct ttatctgaaa aaaggcgaac
     9241 agaaagagga ttcaatcaag taagcgagat gttgaaagca gcaagaattc cttttcagat
     9301 gctactcaaa agagagaagc atctgctggc tcaagcaaaa aacacgcgaa aggaaagatt
     9361 ggagatgcct caaccttttg aacttgcagt caccttttct aagatacaaa ataaaaaaat
     9421 attgattatt gatgatgtct atacaacagg acagactctt ttccacgcag cagattgttt
     9481 gcagatcgca cagccgaaaa tcatccgaac tatttctttg gcgagatgaa ttagatgtgg
     9541 aaatttgata gcgatttaat ttgcaaataa cctagagttc gatataatag aattaagaag
     9601 agggaaagag tggtccttct ccttcttgat tgtggtagac gaaaggggta atttttatgt
     9661 ttagatataa tgtacgcggc gaaaatatcg aagtaactga agcgattcgc gactacgttg
     9721 agaaaaaagt aggcaaacta gaacgctatt tcagtgacgc acccgatgca acggcgcatg
     9781 tgaacttaaa agtttataca gaaaaaacag caaaagtgga agtaacgatc ccattacctt
     9841 atcttgtatt acgtgccgaa gaaacttctc cagatttata cgcaagtatc gatttggttg
     9901 ttgacaaatt ggaacgccaa atccgcaaat tcaaaacaaa aattaatcgt aaatcccgtg
     9961 aaacgggcat gaatactgca aatgctgctg ctttattcaa tgaagaggac gaaaacgaaa
    10021 atgattctga attagatatc gtacgtacga aacgcctttc attgaaacca atggatagtg
    10081 aagaagcagt cttgcaaatg aacatgctgg gacataactt ctttattttt gaagatgcag
    10141 aaacaaatgg tacaagtatc gtttaccgcc gtaaagatgg aaaatacgga ctgattgaaa
    10201 cagactgatc agccttactt aaataacaac gaaaacttgc agcagctact gacagctgcc
    10261 gcaagttttt ttgagtttcc tcctctttta gatgaaatat gaataaatta tgaagttctt
    10321 actttaatac gcttaagata tttcaattat ctataactaa tgataaaatg aaaagtaaag
    10381 tctacatagt ctggataata cacagaagga aaaggagatt acacaacgca tggccaattt
    10441 gattcgttca cttatcgaaa acgataagaa agaactaaaa cgtttagata gcattgcaaa
    10501 aaaagttgaa gcatacgctg accaaatggc agcattaact gatgaacaat tacaggcaaa
    10561 aactgctgaa ttcaagggca gataccaaaa aggagaaaca ttagatcaat tacttccgga
    10621 agcttttgca gtcgtccgag aagcagcaaa acgtgtatta ggtttatatc cataccacgt
    10681 acaattgatg ggtggaatcg tgcttcacga tggaaatatc cctgaaatgc gtactggtga
    10741 aggtaaaacc ttgaccgcaa cgatgccagt atatctaaat gctctgactg gcgaaggggt
    10801 acacgtagtt accgtcaatg aatatttagc aacccgtgac tcgacggaaa tgggcgaact
    10861 ttataatttc ttaggattaa cagtggggtt gaatatcaac tcaaaatctt cggatgaaaa
    10921 acgcgaggct tataattgtg atatcactta tagtacgaat aatgaattag gatttgacta
    10981 cttgagagac aatatggtcg tttaccgcca tcaaatggta caacgtccgc tgaattatgc
    11041 cattgtcgat gaagttgact caatcttgat tgatgaagcg agaacgccgc tgatcatttc
    11101 agggcaagca gaaaaatcca cagctttata tacaagagca gacaacttcg tgaaacgttt
    11161 gaaagaagaa gaagattata aaatcgatgt acaatcaaaa acaatcagtt taaccgaagc
    11221 agggatcgaa aaagcagaag aaacattcgg tttggataac ttatacgaca ttgaaaatac
    11281 tgcattgacc catcacttgg atcaagcatt gagagccaac tatatcatgc ttttagatat
    11341 cgattatgtt gtccaagacg gaaaagtact gattgttgac cagttcactg gtcggatcat
    11401 ggatggacgc cgttattcag atggacttca ccaagcaatc gaagctaaag aaggcgtaga
    11461 gatcgaagac gaaacgaaaa ccatggcgac gatcactttc cagaactatt tccgtatgta
    11521 caagaaactt gcgggaatga ctggtacagc taaaacagaa gaagaagaat tcagagaaat
    11581 ttataacatc caagtatacc agattccgac aaatcgtccg gttatccgtg atgatcgtcc
    11641 agatttgctt tacccaacat tacaaagcaa gttccacgct gtcgtgcaag atatcaaaga
    11701 tcgctaccgc aaaggtcaac ctgtgttagt cggaactgtt gcggttgaaa catctgagtt
    11761 attatcagat atgctgaatc aagaacgtat tcctcatgaa gtgctgaatg cgaaaaatca
    11821 ctttaaagaa gcagagatca tcatgaatgc tggtcaaaaa ggtgctgtga cgattgctac
    11881 caacatggct ggtcggggaa cagatatcaa gttaggactt ggggtaagag aacttggtgg
    11941 tctagcagtt atcgggacag aacgacatga atctcgtcgt atcgataacc agcttcgagg
    12001 acgtgcagga cgtcaaggag accctggtat gtcacagttc tacttgtcat tggaagatga
    12061 tttgatgaaa cgattcggtt cagaacgaat caaagctttc ttagatcgga tgaagatcgg
    12121 tgaggaagat gctgttatcc aaagcaagat gctgacgaaa caagtagaat ctgcacaaaa
    12181 acgtgtagaa ggaaataact atgacacacg taaaaacgtc ttacaatacg atgatgtgat
    12241 gcgtgaacaa cgtgaagtaa tctataaaca gcgacaagaa gtaatcatgg aagaaaaaag
    12301 cttatccaag ccactaatga acatggtcaa acggacaatc agtcgtgtag tagatgcgca
    12361 tacacaatta gagaaagaaa attggaattt ggaaagtatc atcgattttg ccggcagtac
    12421 tcttgtccat gaagatagta ttactcttgc agatatcgaa ggaaaaacag ctcaggagat
    12481 caaagagtat ctaaacgaac gagcacaaga agtatttaat accaaagcgg ctcaactaaa
    12541 tggtccagag caactgttgg aatttgaaaa agtcgtgatc ttgcgtgttg tggactctaa
    12601 atggacagac catattgacg caatggatca attacgtcag tcaatcggct tacgtgctta
    12661 tggacagaac aatccattag tcgaatatca aacagaaggc tataagatgt ttgaagatat
    12721 ggtaggcgcc atcgagtatg aagtcactcg aatctttatg aaagctgaga tccgtcaaaa
    12781 cgtacagcgt gaacaggttt ctcaaggaac agcttctcac tcagaagacg gagatgccaa
    12841 agaaaatagt aatactagcg cgaaaaaaca gccaatccat gtgaacaagg tcggaagaaa
    12901 tgatccttgt ccttgtggaa gcgggaaaaa atataagaac tgtcatggaa aaaatgcaaa
    12961 ctaatttctg acagcaggat tggtgagaca aattcttttt ttaagaattc gtctcacctt
    13021 ctttctgtta tttgctgatt ctgttagact agatataatg aaaaaagtat agtgaaagaa
    13081 ggaaaaaaca tggaaatatc cgaaattcga aatctcctga cagaaatgca ggaaaaggtc
    13141 acaagtttca ggaggtctct ttgacttaga tcagctggaa gaagacatcg cggaagcaga
    13201 agcaaaaatg gctgaacctg gtttttggga tgacagcgaa gccgcacaaa aagtgatcag
    13261 tgaaaataac gctaataaag aaacctatga ccaattccat tctcttgccg aagaactaga
    13321 agaaatcgaa ttgatggtgg agatgctgca agaagaacct gatgcagcaa tgcaagaaga
    13381 agcagaaaca cgtatcaatg cattagatga aaaaatgaag acgtatgaat tatctatgct
    13441 gttagacgga ccttatgatc gaaacaatgc gatcgtcgaa ttgcatccag gggctggcgg
    13501 aacggagtcc caagactggg gcagcatgct tttacgtatg tatacacgtt gggcagagca
    13561 gcatggctat caagtagaaa cactagatta tcaagcaggt gatgaagcag ggatcaagag
    13621 tgtgaccctg ctgattaaag gacataacgc ttttggttat ctaaaatcag aaaaaggtgt
    13681 tcatcgcctt gtacggattt cgccttttga ctcagcgaaa cgacgtcata cttctttttg
    13741 ttcggtagat gtgatgccag agcttgatga aacgatcgat atagaaatca atccagatga
    13801 tttgaaaatc gatacgtacc gagcaagtgg tgcaggtggt cagcacatca ataaaacaga
    13861 atctgctgta cggatcactc acttgcctac aggaacagta gtagctagtc aggcacaacg
    13921 ctcacaattg aaaaaccgtg agcaagcgat ggggatgtta aaagctaagc tttatcaatt
    13981 agaagtggaa aagaaagaac aagaagcagc tgcacttcga ggagaacaaa aagaaatcgg
    14041 ctggggttca cagatccgtt cttatgtttt ccatccctat tctatggtaa aagaccatcg
    14101 gacaaacgta gagacaggaa atgtccaagc agttatggac ggtgaccttg atttatttat
    14161 tgacggctat ttaaaaatgc atctacaata agaacccatt gttaaattga aataaaattg
    14221 taagattttg caagcatgtt gaaacattgc catgctataa tagctaaaga ctgaaaaaga
    14281 tatggagaga acgccatgat tgaaatgaag gatgtaatga agaagtactc aaatggtacg
    14341 accgctatcc gcaatctctc gattgtcatc gaacaaggag agtttgtcta tgtggttggt
    14401 ccgtctggag ccggtaaatc tacattcatc aaattgatgt atcgagaaga aaaagcttca
    14461 aaaggaactt tgaacgtcgc aggtcatgat ctaatagcaa tcaaaaaccg cgaagttcct
    14521 tatctacgca gagaaatcgg cgtggtgttc caagactata aattattacc aagaaaaaca
    14581 gtatatgaaa atgttgcgta cgctatgcaa gttatcggca gaaaacctcg agatatcaaa
    14641 aaacgagtaa tggaagtgct ggaccttgtt ggtttgaaac acaaagttcg agtctttcct
    14701 agcgaattat ccggtgggga acagcaacgt gtctctattg ctcgggcaat cgtgaatacg
    14761 cctaaagtac ttatcgcgga tgaaccgaca ggaaatctgg atccagaaaa ctcatgggaa
    14821 atcatgaaat tattagatcg gatcaatgcc caaggaacta ctgtcgtgat ggctacacat
    14881 aacagtacga tcgtaaatac gattcggcac cgagtaattg ctatcgaaaa cggccgcatt
    14941 attcgagatc aagcggaagg ggaatatgga tacgatgatt agaacctttt tccgccattt
    15001 attagaaagt atcaagagtt tgaaacgtaa cggctggatg acagttgctt cagtcagtgc
    15061 ggtaacgatc acgttgactt tagtcggtgt attcatggca gttatcatga atgcaactaa
    15121 attagctcag gatatagaag gaaacgttga tgtatctgta ttcgtagata tcggtacaaa
    15181 agacgaagag atgaaaaagc tagaaaaaga attgaatgac ttagatcatg ttaaaaaagt
    15241 tgaattttca agtaaagaac aggaattgaa aaaaatccaa aacgaaatgg gtgattcctg
    15301 gaaattgttt gaaggtgaca ataacccgtt atatgatgtg tatgtagtaa gtgctactga
    15361 tccttcttat acaaaacaag tagcagaaga agcagcagat ttgaagaatg tttctcgttc
    15421 tgattacggt ggagcttcct cagatcggat tttccaaatc gctggtgcag ttcggacatg
    15481 gggattagtt gcagcggcat tgctgctgtt cgtagcgatg tttctcattt cgaacacgat
    15541 tcggatcacg attttgtcta gacagcgtga aattcaaatc atgcgtttag tcggtgcaaa
    15601 aaatggatat attcgctggc cgtttttcct tgaaggtggc tggatcggtc tgatcggtgc
    15661 gattcttccg attttgatca tcacatttgg ttatgcatgg tttttccaat tgatcaatcc
    15721 atcattatta cgttcccatt attcattgat tcatccacaa aatatcgttt ggaaaatcaa
    15781 tcttttaatg gtcggcattg gtgtgatcat tggttcactt ggctcgatca tttctatgag
    15841 acgtttcttg aaattctaat accacaatat aaataaaatg agaaagttgg acagtttcgt
    15901 tccagctttc tttttttatt ggctaggaga atagaaggaa gcggcttttt tccctttact
    15961 ttaaaaaaca acttgggtat tcttaagttg gtagaggaag aggtgaagcc gtgaaaatta
    16021 tcgttgacaa tttttttacg atccttttga ttatgaatat tttgctttcc tttatcatcg
    16081 tttttcgaga aagaaaggaa actgctcaaa catgggcatg gctgctcgtt ttgatgttca
    16141 ttccagttgt aggatttatt ttatatattt ttttaggaag agggatttcc aaagagaaaa
    16201 tctttgattt gaagatccaa gggaaaatcg gtaagaacct ggaaattgaa gaagacaaac
    16261 aggcattgat gcgagggctt tatcctcatc cgcctactgg acaagtagat gtgaaacaat
    16321 tgatctatat gctcacggta tttgaaagta cgctctatac gactaaaaat gaaatcactt
    16381 tatttacaga tggtcgtgaa aaattcgatg cgctgattga agatatcaag caagcagaag
    16441 accatatcca cttccagtat tatatttatc gcagtgatgc attaggtgaa gaagttcgag
    16501 atgcattgac agaggcggca agacgagggg taaaagtcag agtccttctt gatgcatggg
    16561 gttccacaca agtttcttcc agcttttttc agaatttgaa aaaagcaggc ggagaaatcg
    16621 catttttctt tcctctattt gttccgtata ttaatcctcg gatcaattat cgcaatcatc
    16681 gtaaaatcgt agttattgat gggaaaatcg gatatacagg tgggttcaat gttggaaatg
    16741 aatatctagg attggtaaag aaatttggtt attggcgaga caatcatttg cgtatttacg
    16801 gagaagcggt gtatatcttg caaaaccgtt ttttgatgga ctggaattct cagcatacaa
    16861 aagaagtagg ctattctccc aaattttttc cgtccattca ctctactggt gatatagctg
    16921 ttcaaatcgt gacaagcgga ccagataccg aacatgaaca aatcaaaatg acttatttga
    16981 aaatgatttc gttagccaaa cgggagatat tgatccaaac gccttattac ataccggatg
    17041 gatcgattca tgaagcactg aagttggctc ttctttcagg cgtaaaagtt catatccaaa
    17101 tatctaacaa accagatcat cttctcgttt actgggcaac gtattctttc gctgcagagc
    17161 tgatcgagta tggagcaagg atcgaaacat atgagaatgg atttattcat gcaaagacga
    17221 tgattatcga tggtggcatt gtttcagttg gctcagcaaa tatcgatgtt cgttcatttc
    17281 gcttggactt tgaggtcaat acactgattt atgatgaacg aatggcttca cgtgtaagaa
    17341 aagcattttt tgaagactcg aaaatttcta cgcatctcac aaaagaaatg tatgaaaacc
    17401 gaggaataat catcaagatg aaagaaggat tagcaagatt gatttcgccg ctcctttaaa
    17461 acacaaaaag gacatgagaa ccatcaacag atggagatgt cgtgtccttt tctaacgggg
    17521 ccatttctga gagtacgtca gaaatggaga aagcgtctcg catgagcgaa attaactttg
    17581 gggtatctct tgttttttgg ggaaagcaag aaataagcta atatatgcta ttaaaagaga
    17641 cacatttcaa agccagtata gcatagaaac ttttaatgag atagtttttt ttacaattat
    17701 gaggatttat tttgttattt aatgattttg attcgttttc atcaagtaat gaaaatgata
    17761 aaataaacat actttaggat taaaggagat ttctaatgaa aaaacttaaa ttattcttac
    17821 caataatagg attagctatt cttttatcag gctgttcaaa gtggattgat cgaggagaat
    17881 ccattacggc tgttggctct tctgctttac agcctttagt agaaacagtt gctgaaactt
    17941 accagacaga aaatcctgga aaattcatca atgtacaagg gggcggaagc ggaactggtt
    18001 tgtctcaagt acagtcagga gcagtcgaca tcggaaactc tgatttgttt gcggaagaaa
    18061 aatcggggat cgatgcctca gcattagtcg atcatcgagt agcagttgtt gggatcactc
    18121 ctattgtgaa caaggatatt ggcgtaaaag acatcagtat ggaaaacctg aaaaaactat
    18181 ttacaggcga gatcaaaaac tggagtgaag tcggtggaaa agatcagcca gtagttatat
    18241 tgaaccgtgc ttcaggaagc ggaacccgta gcacgtttga aaaatgggta ttggacggag
    18301 aaacagctgt tcaggcacaa gaacaagatt caagcggaat ggtgcgccag atcgttgccg
    18361 acacacccgg tgcaatcagc tatgttgctt tttcttatgt ttccgatgat gtagatacgt
    18421 tgaatgttaa cggtgtagaa ccgacagatg aaaatgtgac aacgaacaaa tggacgattt
    18481 gggcatatga gcatatgtac acaagagatc atccaaaaaa actgacaaaa gaatttttag
    18541 actatatctt atctgatgaa gtacaagata acatcgttgg agaactaggt tatatccctg
    18601 tttctcatat gaaagtcgaa cgtgattggc aaggaaatat cgttaaagag taatctttac
    18661 acaaaattta caaacttagc taaactttta catgttatta aaaccaaatt gatgttcaat
    18721 ttgtacactg agtgagtatg ttaaacctga ttaaggggga gtcatctgtg gaagatgtga
    18781 aaaaagtatt attaacaaaa tcaaaacgtt caaaaatgga acagcgtgga aaattcatca
    18841 gttttttatg tatcgcgctg atcgtgttgg ttgtattatc tattttttat tttgtagcta
    18901 gtaaaggatt ggccaccttt tttactgata agatcaatgt atttgatttt ctgtttggta
    18961 cagattggaa tccaagccaa atcggagcaa atgggaaacc aatggtaggg gcattgccta
    19021 tgatcacagg ttcgtttatt gtgacctttt tatctgctat tgttgccaca ccatttgcca
    19081 ttggtgcagc agtattcatg acggagatct ctcctaaaaa cggaacgaag atcttacagc
    19141 cggtcatcga gctgcttgta ggtattcctt ctgtcgttta tggttttatc ggtttatcag
    19201 ttatcgtgcc ttttgtcaga agtatttttg gcgggacagg gtttggtatc ttagctggta
    19261 catttgtgtt gttcgttatg atcttgccga ctgtcacaac gatgactgtt gatgcattaa
    19321 aggcagtacc acggcactat cgggaagctt cattagcgct tggtgccaca agatggcaaa
    19381 caatctacaa agtcgtgcta cgagcagccg tgcccgggat tttaacagca gtcgtttttg
    19441 gtatggctcg tgcgtttggt gaagccttag ctatccaaat ggtcatcggt aatgcagcat
    19501 tgatgccaac aggacttact actcctgctt ctacattgac gtccatctta acaatgggaa
    19561 tcggaaatac aatcatggga acagttgaaa ataatgtgtt atggtcatta gcgctgatct
    19621 tgctattgat gtcattattc tttaatatcg tgatccgtat gattgggaag aaaggagagc
    19681 tgaaataatg aacgcaaaac gctcagataa aattgctaca ggtgttttat atgtagtttc
    19741 ggggatcatc gtattgattt tagcagcttt actactttat atcttagttc ggggaatacc
    19801 gcacatttca tggtccttct tgaccgaacc ttccaaagcc taccaagaag gcggtggaat
    19861 cgggatccag ctatttaact cgatttattt gcttttgatc acgatgatca tcagttttcc
    19921 tatttcttta ggtgcgggta tctatctttc agaatatgct ggaaaaaact ggctgacaga
    19981 tgtgattcgc acgtcgattg aaatcttgag ctcattgcct tctgtcgttg tcggtttatt
    20041 cggtttcttg gttttcgtta ttcaattcca gtatggtttc tcgattattt ctggtgcatt
    20101 ggctttgact gtattcaact tgcctctttt gactagaaca gttgaggagt ctttacaagc
    20161 ggtccattac acacaacgag aagcaggatt ggctttaggt ttgtcacgct gggaaacagt
    20221 gataaaagtg gtggtttcag aagcgacacc agggattttg actggtgtga tcctaagttc
    20281 tggaagaatt tttggtgaag cagctgcatt gatctatacg gctggacaaa gtgcacctgc
    20341 gttagatttt acgaactgga atccattaag tgtttcaagc ccgatcagca ttttccgtca
    20401 agctgaaaca ttagctgtcc atatttggaa gatcaataca gaaggcacga tgcctgatgg
    20461 tgtttctgtt tcggctggcg cttctgccgt gttgatcatt gctgttttac tgttcaactt
    20521 cggcgctcgt gcgattggca aacgattata ccgaaaaatg acttcagcct aaggagaaga
    20581 agcaaaatga aaaaatataa ctggaatgaa acaaatgtca tcaccatgcc aaaagagaaa
    20641 gaagtagcac tatatacgga tgatctacat gtctggtatg gcgacaatga agcaatcaaa
    20701 ggagtggatc tggaatttga aaaaaataag atcactgcac tgattggtcc ttccggctgc
    20761 ggaaaatcta cgtatcttcg ttcgttgaat cgaatgaatg atgggatcgc taatacgaaa
    20821 atcactggga aaatcatgta tcaaggcgta gatattaatg cgcctcaagt ggatgtttat
    20881 gagatgcgca aacggattgg catggttttt caacgtccta atccgttcag caagtcgatt
    20941 tatgacaata ttacatttgc tttgaaacag cacggcgaaa aaaacaaaaa gaaattagat
    21001 gaaatcgttg aaacaagctt gaaacaagct gccttgtggg accaagtaaa agacagcttg
    21061 gacaaaagtg ccttggcttt atctggcggg caacagcaac gtttatgtat tgctcgtgcg
    21121 atcgcgatga aacctgatat cttgctgcta gacgagccgg caagtgcttt ggaccctatt
    21181 tcgacaggaa cggttgaaga aacacttgta aacttgaaag aagactatac gatcatcatc
    21241 gtgacgcata acatgcaaca agcggctcgt atcagcgact atactgcctt tttctatcta
    21301 ggaaaagtaa tggaatatga caaaactaac aagatattta ccagaccaaa aattcaggca
    21361 accgaagatt atgtgtccgg tcattttggt taagacggag gcctcaacat gacaaaagaa
    21421 attatttcat ctaaagatct tcatctgtat tatggaaaga aagaagcact aaaagggatc
    21481 gatctaagtt tcaatcaagg ggaaatcact gcgatgatcg gtccttctgg ttgcgggaaa
    21541 tccacttatc tgcgttcttt gaaccggatg aatgacctga ttccgaatgt aacgatcacc
    21601 gggagtgttt tatataaaga caaagacatc tatggtccaa aaacagatgt tgttgaacta
    21661 agaaaagaaa tcggcatggt attccagcag ccaaacccat ttcctttttc tatctatgaa
    21721 aatgtcatct atggattgaa attaaaaggg gaaaaaaata aaaaagtcct tgatcaagta
    21781 gttgaagaaa gcctgaaggc agcgtctgtt tgggatgatg tgaaagacaa attgcataaa
    21841 agtgctttat ctttatccgg tgggcagcag cagcgtgtat gtatcgcacg tgttttggca
    21901 gttaatccgg aaatcatctt attggatgaa ccaacaagtg cgcttgatcc tgtttctact
    21961 gggaaaatcg aaagtatgct gttagaatta agagagcggt atacgatgat catcgtgacc
    22021 cataatatgt ctcaagcttc acgtatttca gataagacgg cattcttttt agatggtcac
    22081 ttgatcgaat acaatgatac gaagaagata ttcatgaatc cagaaaaaca agagacagaa
    22141 gattatattt caggtcgatt tggataagga ggaaacggaa tgctacgtac acaatttgaa
    22201 gaagaattgc tgaatctcca taatcagttc tacgaaatgg ggatgatggt gagcagcgcc
    22261 gtgcacaagt cagttcgtgc atacatcaaa cacgataaaa tcttagccca agaagttatc
    22321 gaaaacgata taaatatcaa taacatggaa acacgcttgg agaagaaaag ttttgaaatg
    22381 atcgcattgc aacagccagt tacaactgat ttgcgtatga tcattacggt catgaaagct
    22441 agctcggatt tagaacgtat ggccgatcat gcggtgtctg ttgctaaatc cacgattcgc
    22501 gtaaaagggc agacgagaat accggaaatc gaaaaagaga tctccgatat gtccgattat
    22561 gtgaaaaaaa tggtggacaa cgtcctagtt gcttatgtca aaacagacga aaaagacgca
    22621 cgtacgatcg ccaatatgga tcaaagagtc aatgactatt tcaatcgaat ctataatgca
    22681 acaatcaaaa atatgcagga aaatcctgag acagtcatca gtggaacaga ctacttgaat
    22741 gttgccagtt atctagaacg gatcggagac tatgtgacaa acatctgtga atggatcgtc
    22801 tacttggcta cagggaaaat cactgagtta aatacgaacc acaatgagat tttctaaact
    22861 aaagcggtga ttctgccgtt tgtttaggaa aagaggttgt gaaatcagcg gttgtgaaaa
    22921 agctgttctg catcaagtaa taagaacagt caaacaaaaa tagctcctca tatttttcat
    22981 ttggctggac ttattaccgc agatgcaagc ttttgaacac tgtttattcg ggaaagggtt
    23041 tgtgacaaaa tatgtcacaa acccttttca tcatttcata gaaaggataa agaatgcaaa
    23101 aaaaaattag catcatcact atatttttta tttgtgtgct tacttcatgg gttattcagc
    23161 atcaagctgc tttatatgaa gtacctgtca tcgagatcga aaaagtacga ataaaagagg
    23221 atcatcaatt gattacagga agactgatga acacgaatca aaaaggagaa tcgatttatt
    23281 tatcggttcc ttatcaaaaa aatcaaatag aaacagcaaa tataaaagcg agacaaatgt
    23341 atctagtcca aatgcatgga gatgaatggc agctagtagc aaaaaaaaat gatggctggc
    23401 ttttcttctt cacaagtatc ttcattggcg ccatgttgct tattggcgga aaacatggtc
    23461 tatttgcttt aggaagtctc atcatcaata tcgttttact tttacttttg ttgctcatct
    23521 ttactaaaat agaagggatt tctctattaa atatatctat cctgttcgtc gttataggga
    23581 tgattattag catattggct ttagatggat ggaatagaag cagtataatc aaaatttcag
    23641 ctgcagttac gagtgttttt ttagcatttt ttatttgtct tttgacaatg aatctttgga
    23701 aagaccaagg actgcgctat gaggaactga attatctgac acgaccgtat cgttctgttt
    23761 ttctttctag cgtactgatt ggaacagctg gaggaacact cgataccgtt atcacagtca
    23821 ttgcgacatt agaagaattg actaagcgac aaccagaaat aacagcgaaa cagttatggc
    23881 tttcgggaag gcaagtgggt cgagatgtga ttggctcgat gaccaatatc cttttgttcg
    23941 tctatatcag tgggtcagtt ccatcgcttc ttttatattt aggaaatcaa tggtcgttca
    24001 aagaaacgat agaacagcat ttatcattgg aatttttacg cgtcattgct ggcagcttag
    24061 gaatagtatt atcgatccct atctcggtcc tcttttttct gactgtaagg aggctgaaac
    24121 gatgaatgta cttattatac ttgttgggat tttagcaatc agcgtgctac ttattggcgg
    24181 tacgcaaggt atgtatattc ttttaggctt attcatcaat ttagggatct ttttcttgtt
    24241 gttattcggt tatcatcaga agtggccgat actggcattg tcggtcatag gatttttatt
    24301 gattgctgtg gttatcttat tttttatcaa cggttataat ctaaaaatgc gtgcagcttt
    24361 tgtgagtata ctgatctttt tattttgttt cctactattg cttcctatca ctgatttttt
    24421 agcaatccaa ggttttacaa cgatagaact agaagaatta tctggcttag ataagacttt
    24481 agcgattgat tttagattac ttacgagatc gttgcttctg attagtctta gtggtgctgt
    24541 tttagatgcg agtgtagcaa tttctagtgg gacattcgaa gtatatcagg caaatccgca
    24601 attatctttt taccaattgc gccattctag tttcgctatt gctaaaaaaa tattggcgtc
    24661 aacagtaatg acacttcttt ttgcattcat gggaagttct ttagcgttga tcctctggtt
    24721 tattgattta gacattcctt ttcagcaagt gatcaatgaa aaatcatttg ttctagaata
    24781 tacgatggct attcttacca cattgtccgc actacttgtt cttcctttaa cctgcgtgac
    24841 tacagcatat ctctttacaa aaaagaaaga acaactcaag atggagtaaa agttacaact
    24901 taagtcctat gacattttta ctgaatcagt gcataatatg gatgtaagga aaagcttgca
    24961 aacaattttg cttaaggagg caatttccat gaaagaaaga gaacgtattt tagatttagt
    25021 gaaaaaagga atcctttcga ctgaagaagg cttagattta ttagaaagca tggcaactga
    25081 aaaagacgaa aagcaaatca aaaaagaagc agacaaggta actgctagtc ataaagaaaa
    25141 agatcaggca agtcaattga tcgataaact tgaaaacggc gaagaagaaa tttctgagcc
    25201 agttgatcca aaggaaagag aaagacaaga tcaagaaaac ttagaaaaga tcttagatga
    25261 actagcaact gaagcgaata aaacttcggc gcgtctagat gaagtaaatg ctcaattcgc
    25321 tgacaataag gcagcacgca atgagaaaca ggaagcattg atgcagctga atacaaaaga
    25381 agaattaggc gagttgacag aagaagaatt agcacagcgt cagacgttag aagcagaaat
    25441 caaagagtta gaagctagtg gcgatacact gttagaagaa caattgaaat tagaagcaga
    25501 attaaaagat atccgtaaga atcaatggtc tgagaaaaaa gaaacgttta ctgataagtt
    25561 tgaattgcca gatgattgga aagatcaagc aacagataca ctgaatcaag taggcgaaaa
    25621 aatgtcagaa gctggatcac agttaggaaa attcttgaag aaaacattcc aaactgtttc
    25681 agaaacagtg aatgacaaca tggaatggaa agatgtcagc ttgcgtgttc ctgggattgc
    25741 gacaacgaaa tttgagcatg aattttacta tgaagctcct gcagcaagta tccttgatat
    25801 caaggcagca aacggaaacg tgacgttaaa aacgtgggac agcaacgatg tgaaagttga
    25861 agctaagatc aaactttacg gaaaaatggg tgctgaacca tttgaagcat tctctgaacg
    25921 gagccagatt gaggttaatg aagatcatat ctccttccaa attccaaata aacgtgtgcg
    25981 tgcagacctt gttttctact tacctaaacg agtatacgac cacgcagcta ttaaacttct
    26041 aaatggcaac atcatgattg aaacattgga agctaaagat atttatacaa aatctacgaa
    26101 tggtaacatc atcgtggacc aattaactgc aacgatgctg gaagtagaag gtgtaaacgg
    26161 caatatcgat attcgaaacg ggaacatctt agattctatt atcgaaacag taaatggtac
    26221 agtgacattt ggtgcgacag cagaaaacct ttctgtgtct ttggtaaatg gtgatgtacg
    26281 tcttacgatt aaagaagata atttgaaaaa agtagaagca agttcagtga acggaaatgt
    26341 caaagtcgct ttaccagatg gcatcggttt ggaaggacat gctaaaacaa gtcttggaag
    26401 tatcaacagc cgtctgtcca attacgaagt agttcgtgag aaaaaagaac ggacaaacca
    26461 aatgttgcaa ttccgtcgtg tttcagatgg tgaaatcgcg caagtgcaac tttcaacgac
    26521 aacaggaagt atctatttaa aagatacaga taaataaaga ggttgtgaaa gagatgttca
    26581 gccttgagca ataagaagcg attttgtaaa atagcttccc ctattttaca aaattgtgcc
    26641 ttattgccga taggctatct cttgaacacc gtttaccaag agattatgaa cttgccaatt
    26701 atcgccgagt cacaaggaat aatttcaaaa aaagctcgtc acgttttatg aatatggtaa
    26761 tttgtgaccg agaattttgc aaaaagacac cgattaagaa gaaggttgtc acaacgattt
    26821 tcttcattta aaatagtaga acagaggtga gacatgatga aaaaaaagtt gacaaaatcc
    26881 aataaaaatg ttgttttgac agggacttta gcaggaatag gagaatacat cgggattgat
    26941 ccgactgtta tccgtgtgct ttatgtattc ctgagcttag ttgcttttgg aagtccaatc
    27001 attttataca ttttattagc tttgattatc ccatctgcgc gttctgcacg aacaaactat
    27061 ggacataaca atgcatatta tgaaaaaaac aattatcgtg aacaaactcg tgaacaaaca
    27121 aaaaaacgca aagaagcgga aaaaatcgat gatgacgaat ggagtgactt ttaatgtcgt
    27181 actttcaacg tattttagtt aatacgttaa cattcatatc attggctgtt ctttttcctg
    27241 cgatggtcca tgtgagcagt atttggacgg ccgttcttgc cagcttcgta ttgtctgtgt
    27301 tgaatatgtt tgtcaaaccg attttgacga tactgtccct gccctttaca ttagtcacat
    27361 tgggattgtt tacgtttgtt atcaatgcag cgattcttaa aatgacctcc ttttttgtgg
    27421 gagcagaaca ttttagtttt tcttcattcg gtgcagcgtt gttagtagct atcttgatgt
    27481 cgcttgtcaa tgtaattgtc agcgaacata acagtagaaa ataaaagaaa gctgtgccga
    27541 actatcggcg cagttttttt atttagaatc aggaatgcgt tttctattac attggtaatt
    27601 aaataaaaac gtttttttta attggtagta cttttggcta gacaatgata aaatgataga
    27661 gaacactcta atagaaatga ggtagcatga atgtcagaag ttgtaaaagt tagccaatta
    27721 gtgaaaaaat tatctttgga aatcgtgaca ggcgacgaga aaagcttaga ccgtgtcatc
    27781 gtaactgggg acatctcacg cccaggacta gagttgactg gttattttaa ttattattcc
    27841 cataatcgtt tacagctatt tggcagtaaa gaaatcagtt ttgcggaacg gatgatccca
    27901 gaagagcgtt tgatcatcat gagaagatta tgtagtgaag atatgcccgc atttattatt
    27961 tcaagaggat taccagctcc agaagaaatg atccaggcag caaatgaaaa tgggatagct
    28021 gtactgcgtt ctcccatctc aacttctcgc ttattaggag aattatccag ttatttagat
    28081 ggtcgccttg cccctcgaac aagtgtccac ggtgttttag tggatgttta cggattaggt
    28141 gtactgattc aaggtgacag tgggatagga aaaagtgaaa cagcgttgga gttgatcaaa
    28201 cgcggtcatc gattgatcgc agacgatcga gtagatgttt atcagcaaga tgaattaacg
    28261 gtgatcggag aaccgcctaa aatcctggaa catctgattg aaatccgagg aatcgggatc
    28321 attgatgtaa tgaatctttt tggtgcgagt gcggtacgtg gctctatgca agtccagttg
    28381 gctgtttatc tggaagcatg ggcaaaagat aagaaatacg accgtctggg ctctgaagac
    28441 acgaccgttg aaatcgcgga agtaggcatt ccacaaataa aaatccctgt caaaacagga
    28501 cgaaacgttg caatcatcat tgaagtagcc gcgatgaatt tccgtgcacg tacaatgggc
    28561 tttgacgcaa cgaaaacatt tgaagaaaga ttaagtcgct tgattgaaga aaactcaggc
    28621 aacgactagc aaggagtgac aatatgttag cacaaatcaa tcgagttgct tttgagcttg
    28681 tagggattcc tatctactgg tatgcattga tcatcgtatc aggtatcatt atcgccatgt
    28741 ggcttagcag cagagaggct gttcgggtag gattaaaagc agatgatgtg acagatttta
    28801 tgttgtgggg attgcctatc tccattattg gcgctcgctt atattatgtt ttatttgatc
    28861 ttccccagta tatagctgat ccaatccaaa tattcaatat ccgttcagga ggcttagcta
    28921 tttatggcgg actgattgca ggcgcgatca cgctgtattt ttttactaaa tatcatttta
    28981 tttctttgtg gactttttta gatatcgctg caccaagtgt attattagca caagcaatcg
    29041 gtcgttgggg aaatttcatg aaccacgaag catatggacc agacacgacg cgaagcttct
    29101 tagaaagtct gcatttaccg caattcatca ttgataatat gtatatcgaa gggatctatc
    29161 gtcaaccaac atttctttat gaatcacttt ggagtttgat tggatttatt ttgcttttgt
    29221 ttttacgaaa gaaaccacac cttttgaaaa aaggtgaagt ccttttatgt tatctaatgt
    29281 ggtatagttt cgggcgtttc tttattgaag gattacgtac agacagtctt tactttttag
    29341 gtgtgatccg tatttctcaa ttattatctg ctgtgttatt tgtcggtaca ttgattctat
    29401 ttatttggcg cagaaaaaaa ggaaatttac cggattatga ccgctcatta ggaaaaaatc
    29461 aacaaattat ctgattttta gagcgttaaa aatgaaaaaa atttcaggag tggtaaaatg
    29521 aattatagag tagcggtttt aggaccaggc tcttggggta ctgctttggc acaagtcctc
    29581 gccgaaaacg gacatgacgt tcggatttgg ggacatcgtg cttcacaagt agaagaaatc
    29641 aacacccaac acacgaatca acgttattta ccagatcatt gtctacccga ttccatccaa
    29701 gcattcacca atatggaaga tgcagtaaaa gacgcagatg cggtgctatt cgtcattcca
    29761 acgaaagcaa tacgttctgt tgcaaaagaa ctagtgccta aattgaatac aaagccagtg
    29821 atcatccatg caagtaaagg attagaacag gggacacata aaaggatctc tgatatcttg
    29881 ttagaggaaa tcccagtaga aaaaagaaaa gctgttgttg ttctttctgg accaagccat
    29941 gcagaagaag tagcgaaaca tgacatcact acgatcacag ctgcaagtac agatgcaaaa
    30001 gcagcaaaat atgtacaaga gctgttcatg aataattatt ttcggatcta taccaatcct
    30061 gatgtgatcg gtgtagagat gggggcagct ttgaaaaata ttattgctat tggtgctggc
    30121 gctattcacg gcttagggtt tggcgataat gcaaaggcag caatcatgac gcgcggatta
    30181 gctgagatca gccgtttagg tgtagcaatg ggtgccaacc cgctgacctt tatcggatta
    30241 agcggagtag gcgatctagt cgttacttgc acaagtgttc attctaggaa ctggcgcgca
    30301 ggcaacttgt taggacaagg gcagccccta gaagaggtgc tagccaatat gggaatggtc
    30361 gttgaaggtg tgaatactac ccaagcagcg atggaactag cccaaataat ggaaatcgaa
    30421 atgcccatca ctcaaacaat ctatgaagtg ctgtatgaac aaaaagaaat caaaacagcc
    30481 gcaaaagaaa tcatgttacg tgatgggaaa aaagaaaatg aattctcatt aacaattttt
    30541 tgaaggagcg aatgtatatg aaagtcaaaa aagcagttat tccagcagca ggattaggaa
    30601 caagattttt accagcaaca aaagctatgg caaaggaaat gttgccaatt gttgataaac
    30661 caacaatcca gttcatcgtt gaagaagcgt tgaaatcagg tatcgaagac atcttgatcg
    30721 ttacaggaaa agctaaacga ccaatcgaag atcactttga ttcaaatatt gaattagaaa
    30781 caaacctaag tgaaaaagga aagaccgaat tattgaaatt agtagaagaa acgacagatg
    30841 tcaacttgca tttcatccgt caatctcatc caaagggttt aggacatgcc gttcttcaag
    30901 caagagcctt tattggaaat gaaccatttg tcgttatgct aggcgatgat ataatggaag
    30961 acgaagtacc attgacacag caattaatcg atgattacga acgtactcat gcttctacga
    31021 tcgccgttat gcaagttcct catgatgaaa cttcaaaata cggaattatc aatccaggag
    31081 aagtattgga agatgggtta tacaatgtca aaaactttgt tgaaaaacca gatccaagca
    31141 aagcaccaag tgatttagct attattggac gttacttatt gactccagaa atttttgatg
    31201 tattgtccga gcaacaacca ggagccggaa atgaaatcca actaactgac gcaatcgata
    31261 cattgaataa aacacaacgc gtatttgccc gtaaattcac aggtaaacgt tacgatgtcg
    31321 gtgacaaatt tggttttatg aaaacaagta ttgaatatgg tctaacacat ccagaagtag
    31381 gtgcaccttt acgtgagtac atcctgtctt taggtaaaac attagaagca gaaggaagca
    31441 agatcgatca taatccaaaa ggaataacag aaatcaaaga agaaaagaaa aaataaccct
    31501 tttttctaac gagcttcagc tgctaattga ataaaaagta gttgaagctc gtttttattt
    31561 gtttaaaaaa cacgaaaatg ctatccttat agaaaagaga gacaagaagg gagtttgatc
    31621 atgtcaggag gagaaattgc aggattgatc gcagcaatcg cctttgcgat acttgtcgtt
    31681 tttatcgttc gtgtgttgtt gcaagtttct aaaactttag aaaaagtaga tcagactgta
    31741 gcagaagcaa atacgacgat cgaaatcgtc acaaaagacg tagatctttt gtctagacaa
    31801 gtagaaggct tactggtcaa aagtaatgaa ctgctcttgg atatcaatgg aaaagtcgca
    31861 acgatcgatc cattgttcac agcagttgct gatttaagtg aaagtgtatc agaacttaat
    31921 cattctagta aaaacatcgc gacgaaagtc ggcggaatcg gtaaaacgac agctaaagcg
    31981 acggttgccg gaaaagtcgg tgggacagcg atgaaatttt ttaaaaacaa aaaacatact
    32041 gaaacgacag gaggaaaata aaaatggcta aaaaaggtgg atttttatta ggtgcagtag
    32101 tcggaggcac agccgcagca atcgccgcgt tattgttagc accaaaatct ggtaaagaac
    32161 ttcgggatga attagctgcc caagcggatg atttgatgga tatggcttca gattacacag
    32221 atatggcgaa agaaaaatcg actgagttaa caggtattgc aaaagaaaaa gcgcaagatc
    32281 tttctcaaca agcaggtgat ctagcaggta gtgtcaaaca aaaagtaagt gaatcagcag
    32341 atgaagcagg aagtgaatct gacgatatct tgttaaatct taaagaacaa tcagctgact
    32401 tatctaatcg tttcaaaaaa acggcagaag atatgaaaaa acctgcagat gaattaggaa
    32461 gtattgctaa agatacttca gaagatatca tgattgatgt aaaagacgct gctggtaaag
    32521 caggagatac tgtcaatgaa ggaatgtcag aagcaaaacc agttgcagat gactcaaaag
    32581 aaatgatgaa aatggcaaaa gaagatgcga aagaagctaa aaaagaaata aaagatacaa
    32641 tgacagattc atctacaaat cactaaaatc acaaatttat agaataaaaa ggtgggagcg
    32701 gactagctct cacctttttt actcttattt ttctaaaaca agtaattctt ttggtgtagt
    32761 cgtgaatggc acacagccat cgcttgtcac atatacacag tcttcgatac gtacccctac
    32821 tttttcagga atatagattc ctggttcaag agagaagcac atcccttctt cgattactaa
    32881 gtcatttcct tctacaaggg aagggaattc gtggacggtt gttccgatcc cgtgacctaa
    32941 acggtgattg aaatattcgc cgtagccata gctgttgatc acgtttcgtg cgatttgatc
    33001 aagttcacct gctgtcacac ctggacggac ggcttcttgt gcggcaagct gtgcttcaag
    33061 agtgatgttg tagatttttt cttggaagtc ggttggtttt tgataagcaa ttgtacgagt
    33121 agcatcactg caatagccat tccaaacaac gccaagatcg aataacacaa gttcattcgg
    33181 tgaaatcttc gtatttcctg gtgtaccatg agggcttgca gcatttgctc ctgcaaggac
    33241 taatgtgtcg aaagacattt gtgaaacacc ttgttttttc aattggtatt caatttctgc
    33301 aatgatcgct tgttcagtca cgccttcttt cactgcttta aagccaatct caaatgcaac
    33361 atcggcccat ttaccagctt cgatcagttt gtctttttcc tctagagttt tgatcagttg
    33421 tagacgttgg atgatggaag ttagatcagt gtaagaatcc gttcccgtca agatatcaga
    33481 gatagcatcg aagcgctcga cagtcaaggc gttcttttca atccctacat tgccaggctg
    33541 accatagcga gcacgaagtt cttttccgat gatctcccaa gggttttcgc tgtctaaata
    33601 gccacggaca tcatacgccc aactactgtt ttgagcatct tcaacttcca aagcaggagt
    33661 gaaaaggaaa ggatcttgtt caagagggat aaaaagagct agtacacgct catgaggatc
    33721 actttcgtat ccggaaaagt aagcgatgtg gccagggtcg ctgatataag ccaattcgac
    33781 ttggtgttgt gccatccatt gacgtagttc attgattttt acgttattca tttggcaacc
    33841 tactttctaa attaattttg tattcaataa ttgtaccact gatttattaa aagaccaacg
    33901 ttctaaaaac tgaaaaaagt aaaaattttc atgaaaacag agataaaacg gttgcaattc
    33961 ttgagattat ttgatattct attttagaaa tgtaagacgt attttcagaa aacatataaa
    34021 atatgaatag gagaacacaa atggaaaagc aaacaatcac tatctatgat gtagcgagag
    34081 aggcaaatgt ttcgatggct actgtttcac gtgtcgtaaa tggcaatcca aacgttaaac
    34141 cagcaacaag aaaaaaagtc ttggaagtta tcgatcgctt ggattatcgt ccaaacgcag
    34201 ttgcgcgtgg cttggcaagt aagaaaacaa caacagttgg tgtaatcatc cctgatgtca
    34261 gcaatatgtt ctttgcttct ttagcacgtg gtatcgatga tgtggcaaca atgtacaaat
    34321 acaatattat cttagcaaat tcagatggca acgaccaaaa agaagtcaat gtattgaata
    34381 acttactggc taagcaagtg gacggcgtga tcttcatggg tcaccatatc acagacgaaa
    34441 tccgtggaga attttcacgt tcaaaaactc ctgttgtatt agctggctct attgatccag
    34501 atgaacaagt aggtagcgta aacattgatt atgtatccgc aacaaaagat gcagtaaaca
    34561 aattggcaaa aagcggcaat aaaaaaatcg cttttgtcag tggtgcgttg atcgatccca
    34621 tcaatggaca aaatcgtctg aaaggctata aagaagcatt aagcgaaaat aacctaccat
    34681 atagcgaagg attgatcttt gaagcacaat acaacttcaa agatggtcta tctctagtcg
    34741 atcggatcca taatagcggt gcaacagctg tctatgtttc agatgatgaa ttagccatcg
    34801 gtattttgga tggtttatta gaccgtggcg tgaaagtacc ggaagaattc gaaatcatca
    34861 caagtaacaa ttcactactg acagaagtag ctcgtcctcg tttaacaagt atcacacaac
    34921 cattatacga tttaggggct gtatctatgc gcctattgac gaaaatgatg aataaagaag
    34981 aagtcgaaga aaaaacgatt atcttgcctt atggaatcga agaaaaagga tctacaaaat
    35041 aataaaagga caaccattca gaggttgtgt gcctgccgtt taactctgcg ttacaaggag
    35101 caatttcaaa aaacagcatc tcatgtttga tgaatattgt gactcgtgat tcggagttgg
    35161 caggagaaca ccgtttattt gggaaaaggg gttatgacaa aattttgtta taatcctttt
    35221 tttgtgtctt aaaaaagaga gaaagtggtt gaaattacat ttatcgtata taaaacaatc
    35281 cgtgtataga tgctgcattt tgttcaccac catcaaaaaa ataagggact gtgacaatac
    35341 tattgtcaca atcccttatt actgtgtatt ctattaaatc aatcatcttt ctcatctgat
    35401 tctttagttg cttgattcgc tcttgcataa gctgaagcgg tgttccagta atctgtatag
    35461 ttttcatcgg taccgccaac gccaaattta aaggcgcttt tcttcggtcc atttttcgcc
    35521 catagcgatt caactgtttt tcctggtgtt tggatggatt ttttattgac agtaactttt
    35581 ccaggtgttt gaccagtaaa tccagatact tttttcttca tcacatcaga tgataattcg
    35641 aatttctcat cagtgccaaa aatgtcaggt tttgcttggt aagcttgatt gatcagattg
    35701 gcaagataat tagccgaacg tatccttgct ttgctgtcca ttccagtatt gtcatcgtgc
    35761 cctgcccagc tactgatggt aatagacgga gtagagacaa ttagccatga atctcggtat
    35821 tcattggtag aaccagtttt tccgacccaa tctgcttttc ctagatttcc gtttaagctt
    35881 gagatggcat ctttgaatgg tgtagtgatt tttgcattga tcacactacg catcatgtca
    35941 ttcatgatcg atgccgttgc ttccgaatag atccggacag agttgctttc gtgtttataa
    36001 attacatttc ctgcgttatc tgtgatggaa tcgatgatat agccttcttc atagacgccg
    36061 ccgtttgcta aagcctgaaa tccgttggtc tgttgaagcg tcgtgacatc tactgtacct
    36121 aaaggagcag attcaacgcc ccaattgtca tttgccgggt agttcatctt tgccaagtag
    36181 tgctcgtaag catattgttt cgatccaccg gaattcaaca catcttgata taagtgataa
    36241 gccgggatat tgttggacca ttctagtgac tcacggacgg tttggaaggt gttcgatcct
    36301 tcgttagtag cattgacgat tttctcgcca gcattttctc cttcttgcca agttgttgca
    36361 taatctgata cacgggattc tgatccgata agccccatgt cgattgcagg tccataaaca
    36421 agaactggtt tgattgatga gccagcttga cgttctgtat cgaaggcatg gttattttga
    36481 ttctgactgt aattccgtcc gccaacgaat ccgtagatgc ggccagttct gttatccatc
    36541 aatacatttc cggtttctac ttgactgcca gcaccatcat ctaacatgta tccataattt
    36601 tcaacgccat tttgcaatgc agcatagaca tctttatcga ttgtcgaatg gattgtatat
    36661 cctttatttt ggatcgtttg ctgtgccttt tgataataag cgtcactgac cgatgaatca
    36721 gacatatcag cgttgtcttt ttcagccaat tgttgtgcaa tgattcttgt tgcttcattc
    36781 atcacagtat aatacaagaa ttctctgtca gtctgttctg cgatttgttg tggtagaaag
    36841 tcttttgtaa ggtcataggc ttttgcttct tcgtattgtt ctttcgtaat ttggccttca
    36901 cgatacatac tgaataaaac aaaatctttt ctggcaaggc cggcagaaag atcttctttt
    36961 agcgcgcctg tgttcgtgta tggactatac gtgatcgggc tttggggtaa tccagcgata
    37021 taagcagctt gcggcagcgt cacatctttt gcatctacac caaagattcc ttttgcagct
    37081 tcctggactc cagcaatgtt ttgtccctta ttattacgac caaatggtga gacattcaaa
    37141 tacgtagcaa tgatctcatc ttttgaaaag tatttttcta cttgtgcaga aagaatgatc
    37201 tcgtttgctt tacgtttgaa tgttgtttca tctgtaagga tctgctgttt gactaattgc
    37261 tgtgtcaaag ttgatccacc agaagagcca ataccagtag cttcagatac taatgctcgt
    37321 aaaacagctt taggaacgta accttggtgt ttatcgaagt attcatcctc tgtgctgata
    37381 attgcagttt tcaataaagg tgaaatctta tcagatgaaa tagtcgtgcg catcagatct
    37441 gtctggattt ttgatatctc tgtattatct gcataaacaa tctttgacgt ttctgtaatg
    37501 tttcctagtt ctgtctgcag tgctttttta gtcggcaatt gtgtgtcttc gacgagatag
    37561 gcaaaatagc cagcgcctat tccaatacct agagctgcga acatcaaaag aagaacagta
    37621 ataaaaacag tcaatgattg aaaaactcta aaaataatct taggaacaaa ccatttttct
    37681 ttttttcttc tattctgttt ttttcgagta tttttgcgtg gcaaaagggt cacctcaact
    37741 aatggtttta tttcgctaat tatagcaaat aatagaacaa aaaaacagac aaggctgttt
    37801 ttggcaggaa tttctttttt aaaagagtta aaacgtgaga aaatgatctt tattataaaa
    37861 gagttcttaa gcttttcttt agagaaaatt tcagttacta tggagaacag ggcaaagaaa
    37921 aatcaatcat tttctttgta tatcatctta ccaatatata ggaattgtta gtaacaattg
    37981 cctttcaagg aggaatccat ccatgttatt aggctcacac gtcagcatga gcggaaagaa
    38041 aatgctgtta ggagcagcag aagaagcagc cagttatgga tcttcgactt ttatgatcta
    38101 tacaggcgcc cctcaaaaca ctagaagaaa agccatcgaa gagatgaata ttgatgccgg
    38161 aaaagcgtac atggcagaaa aaggtctaac aaatatcgtc gttcatgccc cttatatcat
    38221 taatttgggg aatacgatca aaccagaaat gtttcctttt gccgtccaat ttctgagaga
    38281 agagattgtt cgtgcggaag ctttaggcgc tactcaaatt acacttcacc caggtgctca
    38341 tgtaggggca ggaacagaag ccggaattgc tagaattatt gaaggcttga atgaagtttt
    38401 gacaaaagaa cagacggcac aaatcgcttt ggagacaatg gcaggtaaag gtacggaaat
    38461 cggtcgaaca tttgaggaat tagcgcaaat catcgatgga gtaaaattga atgaaaaatt
    38521 atccgttact tttgacacct gtcatacgaa tgatgccggt tataatatta aagaagactt
    38581 ttcaggtgta atggaagagt ttgataagat catcgggtta gatcggctta aagtactcca
    38641 tatcaatgat tctaaaaatc cgcaaggttc gcataaagac cggcacgcca atattggttt
    38701 tggaacaatc ggattcgaca cgctgaataa gatcgtccat gatccaatgt ttgacaatat
    38761 ttcgaaaatc ttggaaactc cctatgtagg caaagataaa aagaaagctt acgcaccata
    38821 tggaaaagaa atcgccatgt tcaaagcgca aacattcgat ccagaagtgt ttcctgagtt
    38881 attagcagaa gaagtgatac tctaagattt tctatctgac agcagcaaaa aaggaccagg
    38941 cacattgcct tgtccttttt tgtttaagaa acaaaggagt actttttgca gtctttttca
    39001 tcatgcatct tctcccccct ctttttaaat ttagacaaac aaggtatact ggtagaaaag
    39061 taaaaaaacg aaaagtttca caagcaagtg gcaaaacgtg attggaagga cgaaaagatg
    39121 ctgaacactt taaaaccctt gatcaaccaa ctaaaaaaga aacatacata ctttattctt
    39181 ggcatagccc tattatttac aattattcgt ttgtatttat atagtaaagc aatctatgga
    39241 acagacatgt cggcaaccta tgatgaccag ctgctgattc gctatgctca aaatattttg
    39301 gacggtaaat ggctagggga gtatacgact acaacacttt ccaaaggaat ctcctacagc
    39361 ttatttttag tacttgcaca taaactgcat ctttcttatg cagttttgtt cggcatgttc
    39421 agtatttttg ccagtatatt ggttgcactc gcgtttaaac cgattgtgaa gaacaagtat
    39481 cttcttttaa gtatctattt ttattttttg ttttctccga ttagttttac acatgaatat
    39541 tccactcgaa catatcgtaa tgccctcgtg attccggctg ttgagatcat tatcgcttgt
    39601 ttattagcta tttattaccg caaatacggt tctagcagaa aattgctgcc atggttttta
    39661 gggctttctg tcgcttttcc tttcttttgg ttcattcgcg aagattctat ctggcttctt
    39721 ccttttactg tagtagcttt gggtatcagt ttcgtccaga tcttgctagg gcaagacttt
    39781 tctttcaaag aagtaaagaa gttaaaaaaa cgactctttc ttctctcgaa acgggaatgg
    39841 ctgaaacttt cattgttttt acttcctata gttggctttt ccatcgtcta tcaatggatc
    39901 gaatataaaa atgagacaac atacggtatt gcaaccatca atgaccgttc cagtggagaa
    39961 tttggacgtt tgatgaaaca actgatccga atagatgatg aaacgaactt gaataaagaa
    40021 aacagtgaga tatgggtctc acatgctgca ctaaataaag cattagccgc atctcctaca
    40081 ttccatactg tttctacccg tattgacgaa ttatatacga ctcacgcgtg gactcaaggt
    40141 ggaaaagtaa aagaattacc cggagatatc atcttttggg cattgcgaga tgtggtaagc
    40201 gaatctggtt attaccaaaa caatgcaaaa gaaaccaatg atttttggaa aaaagtcaac
    40261 caagaattag aagaagccta tcacaaggga acaatcaaaa agaaaaaaga gttctatctg
    40321 atgggatcag gagatggaaa gacgatgagt gatctgccaa tcgtattcga tttccttcaa
    40381 tcaggatacg cttatgcatg gcgatataaa gatttccatc aaggaggaaa ttatagtttc
    40441 ggaacgcaag aacaagtcaa acaggctcaa gaattattaa accttccgct aatggagaat
    40501 tggatcgata gtaatgaacc gagaacacct aatttccaat taacaaaatc agcaaaagtc
    40561 gcgaatgtca tcataaaaat ttaccaagtt ctggctattc ccgtgctgat tgcttcaata
    40621 gcagggatat tacttatgat actaggaacc gtatttgcaa aagctgatcg tgcctattat
    40681 agttcctctt tgattgtggt caccggatta atactgacac aattggtttt tcttttcggt
    40741 gtctcatggt tttgttctta tgcgccagaa aaaaaggact attttttaag tgtctacact
    40801 ggtgcaggcg tgccattaac gcaattcatc gtagtaacaa gcatgctagt tttcagtaaa
    40861 ttaaatctga aaaaagcttt atcttctaaa taaaaagacc cttggtagct agatttttaa
    40921 cctaactatc aagggtcttt gtgtggaaaa atcagttttt attcgatttc ttctaccgtt
    40981 tcctgcaaaa gctgttcata ttttttgttt cctttatata aatcaccaat cgtccatgcc
    41041 aacaggagaa ggacaagaac aatgattaca taagcgatgt gatcagccaa tgctagttga
    41101 gcggaagtgg cttgctcgcc gaagaaactt tcgatctgtc ctggtaatcc tcgtaagttc
    41161 aagtaagtta gactaatcac agagaaccag ccaagaagtt ttacgatgaa tgaattttta
    41221 aatcggctac ccatctccgc ttggctgttg gtcatcatca gtaaaggaat catcgaaaac
    41281 ggcaacgcaa aagccaagaa cacctgggat tcattcatta agttattcaa agcggcatgt
    41341 tcttcgatcg ttccttttgt acttgtaaac aaaacacaaa tcaatacagg aatcacagaa
    41401 agcaatcgtg tgaccagtct tcttagccaa atcgggatac gcatatggat gaatccttcc
    41461 atgatgactt gaccggtcaa cgtaccagta atagtagagt tctggccaga agcaagaagt
    41521 gctacagcaa ataaagtgga caagatacca gattttgcta cagcaatcaa aataccattg
    41581 ctcatagctg atggatcaga taaagcttca tacagaccaa aaaaggaagg atcttggaca
    41641 gaaccggttt tgaagacagc gacacccatg atcaatagca gtgcattgac tagaaaagcc
    41701 attgacaact ggatattaga atcccaagta gaaaaacgta cagcttgtgc tacatcttct
    41761 tcgttttggt gatcgatctt ccgagtttgt gaaactgctg aatgaagata taagttatgc
    41821 ggcatgactg ttgcaccaat aatccctaaa gctccagtca gcggagtttc gccgccgatg
    41881 accggtgagt ctgagaatgt atgactgtta gggataaagc cagcaaataa actgtgccaa
    41941 tctgggttag acaagccaac ttgatagaca aaaacgaata aaatgacgaa aattaagcag
    42001 acaaccagtg cttcgatctt acgaaacccg acttttgtca gtagtaagag aacgaaaaca
    42061 tctaatacag taataaagac ggcaatcacc aatggaatat caaaaagtaa gtagagggcg
    42121 attgctgcac caatgacttc tgcaatatct gttgccataa tggctaattc agtcaagatc
    42181 cataaaatga cacctaatgt cttacttgtg cgtgctcgga ttgcctgtgc caaatccatt
    42241 tggctcacga ttcctaattt tgctgccata tactgtaaaa gcatagcaat cagactagac
    42301 atcaaaataa ctgacatcaa taaatattgg aaattttgtc ctccggtgat cgaagtagac
    42361 cagttacccg ggtccatata cccaactgct actaacgcac caggtccaga gtaagcaaga
    42421 agtgttttaa aaaaactttt cccctttggt acatcaactg ttccatttac ttcagctaaa
    42481 gataaaccat ttgtatgttc aataagtcga tgcttatgaa attgtttatt ggattgatta
    42541 ttcaagaaaa aaccaccttt cctatttatc tacgattaca ttctacacct caaaaagaaa
    42601 aaattaaaga aaaagattcg gtacgcctaa ttttttttca tggcgcgtct tgctagatga
    42661 cgaaagaaat tttgttctcc tctaaaaaaa ccactatttt ttgcatgaaa ctaaagaata
    42721 cgcctttctt ttttcaataa actttagtaa aataagtcat tgagagcaat tcggaaatag
    42781 aaaggagaga tttatatgtt atcaacaggt attgtcgtac ttattgctat tattgctttg
    42841 ctaatcggcg cagtaggtgg ctttttccta gcgcgtaaat atatgaaaga ctatttagaa
    42901 aaaaatcctc ccgttaatga ggacatgttg cgatcaatga tgatgtcaat ggggcaaaaa
    42961 ccatctgaga agaaaattcg ccagatgatg cagcaaatga agaaccaagg gaaaaaatag
    43021 gttctgaccc aacgactttt tacgggctga ttttttcagt ccgtttttta tttcgtaatt
    43081 tgttagacta ttcagattat tcagcaaaaa agacaagcac agacaatcct aggctcttga
    43141 taaagacaaa ggaggagtaa aatgtcgatt tttagaaaat taggctggtt ttttcgtcag
    43201 gaaaagaaac attatttaat tggggttttc tcgctattcg cagtggcctt ggtacagtta
    43261 gttcctccaa aagtgattgg gatcatcatt gatgagatcg ccgataaaaa tttatcaata
    43321 aagatcattt tcgggtggat cttcctattg attatcgctg cttttttaca atatcttttt
    43381 cgttatatct ggcggacgaa tatttgggga agtgcagctc gattggagaa agaacttcgg
    43441 cagcagttat tcaaacattt tacagaaatg gacaatctct tttaccaaaa atatcggact
    43501 ggggatttga tggctcacgc aacgaatgat ttgaatgcga tccagaatgt agcaggagct
    43561 ggtatcttga cctttgcaga ttcagtgatt acgggcggaa caacgatcat tgcgatgatt
    43621 ttgtttattg attggcgctt aacactgatt gcgctgattc ctctgccttt gctggccgtc
    43681 acttcacgag tgctggggtc aaaactccat gatgcttttc gtgattcgca agaagctttt
    43741 tctagtatca atgataagac acaagaaagt atcactggga tcaaagtcat taaaacattt
    43801 ggacaagaaa aagaagatct agcggatttt gaagaaaaga ttgaagatgc aattattaaa
    43861 aacaaacgag tcaatttttt agactcctta tttgatccat tcattacctt gattatcggt
    43921 ctgtcttatg ttgcaacaat tattttaggt ggaaagtatg tcttggaagg cacgatctcg
    43981 atcgggcaga tggtctcatt tattagttat atcggtatgc ttgtttggcc gatgtttgcg
    44041 attggtcgat tgttcaacgt attggaaaga ggaaatgctt cttatgatcg cgtcaatgaa
    44101 cttttgcatg aaaagacgca tatcgtggaa caactgggtg cagtgcagac cccggcaaaa
    44161 ggcgagctga atgtagctat ttcctctttt aattatccga aagaagaatc accagcatta
    44221 gaacaaatca agtttgcgat ccaagaagga gaaacattag gtattgttgg gaaaactggt
    44281 gcgggaaaaa cgacgatcat caaattactg atgcgtgaat acgatgatta tcaagggaaa
    44341 atccaatttg gcggacgttc gatcaaagaa tattcattga atgctttatt aggatcaatc
    44401 ggctatgtgc ctcaggatca cttcttgttt tcgatgacca ttcgagataa tatccgtttt
    44461 tctaatccaa aactttcaga agaagaagta gagcatgcgg cttctttagc atttatcaac
    44521 aatgaaatca aggaattacc aaaaggttat gataccttag ttggagaacg tggagtctct
    44581 ttatctggcg gacagaaaca aaggatttcg attgctcgag cattgatcaa aaatcctgaa
    44641 ttattaatat tagatgatgc actctctgca gtagatgcca aaacagaaga agctatcttg
    44701 cataatttaa aagaaataag aaaagagaaa acaactatca ttgcagctca ccgtttaagt
    44761 agcgtgatgc atgcaaaaga aatcattgtt gtcgatcaag ggaaaatcat tgaacgagga
    44821 acccatcatg agctgcttgc actaggcggc tggtatgaac aaatgtggga gaaacagcaa
    44881 ttagaagcga agatagaagg aggcgaggcc tgatggatga aaattatcaa tcggaatgga
    44941 caaaatcgat tccacttaaa gaacagaaaa agatcatcaa acgactgatg aagttcgcca
    45001 aaccttttag aagaacgttc atcgttgcta tcttatttgc gtttgctttg tctgtgatca
    45061 atgtcctatt gccaaggatc atccaaactt ttatggatga tcatctggct aaacagtcgg
    45121 ctacgacaca agttattttg ttttttgctg gtatgtactt atttggagtc atagtaaaaa
    45181 gtatcatttg gtttttccaa tggtatttgt attccatggc ctcattgaag acctatcagt
    45241 atattagggt aaaattattt gaaaagctgc atacactagg tatgcgttat tttgatcaga
    45301 caccggcagg atcaaccgtt tctcgagtga cgaatgacac agaaacgcta tttgaatttt
    45361 ggtacgtctt tttgatggta ttgactggga tctttgcagt cgtttcttca ttccttgcca
    45421 tgtttcaaat caatggagaa attgccttgt ggactttggt gtttttgccg attttaggaa
    45481 tcgtcatctg gtattaccag aaattcagtt ctcgtattta ccgaaatatg cgggaaaaat
    45541 taagtcagct gaacacgaaa ttgaatgaat cgatttccgg catgcgtatt atccagcagt
    45601 ttcgccaaga agctcgttta gctaaagaat ttgaacaagt gaacaatgag tatttagaca
    45661 cgcgttatgc gatgatcaaa acgaattcga ttctgttaag tccgatcatc aattttctat
    45721 atgcattggc gattgcgttg gtgttgactt tgtttgggat cgatgcgttg cattctcccg
    45781 tagaagttgg actgatctat gcatttacga cctatgtcca gggatttttt aatccaatgt
    45841 ctcaaatgat ggactttttg agcatcttca cagatgggat ggttgctggt agtcgtatct
    45901 tgaagattat ggatacggaa gaatatgcac cacaacaaaa ccctggagca gatcaaatga
    45961 ttacttcagg taagattgag tttcgcaatg taagcttttc ttatgatgga gagcacaatg
    46021 tattaaacaa tatctctttt gttgctaatc cgggagagac cgttgcatta gtgggacaca
    46081 ccggaagcgg aaaaagctcg atcatcaacg tattgatgcg gttttacgaa ttttatgaag
    46141 gtcagatatt gattgatgat catgacattc gagaatatcc aatggaagag ttacgtaaga
    46201 aaatggggct ggtcttgcaa gatgctttct tgttttatgg ggatatcgca ggaaatattc
    46261 ggatgatgaa tccagctatc acagacgaac agatacgcca tgcggctgag tttgttcaag
    46321 caaacaaatt catcgatgaa ttaccaaaag gatatcactc aaaagtgatc gaacatggtg
    46381 ccagctattc tagtggacaa cgacagctga tcacttttgc gcgaacaatc gtgactgatc
    46441 ctaaaattct agtattggat gaagcaacag caaatatcga tactgaaaca gaaggattga
    46501 tccaagaagg attggcaaaa atgcgtcaag gacggacaac gattgcgatt gcccatcggc
    46561 tgtcaacgat tcgagatgca gaattgattt tagttttaga caaaggtcat atagtagaac
    46621 gcgggaatca tgaaacactt ctagcgcaaa atggtttgta tgcagatatg tacaaactgc
    46681 aaagcagtgg tatataaaag atgttgtgac agtagaattt tgacctaagc actagagtga
    46741 aaataaaaca tagcttctca tatttttcat ctgtgagagt tagtgtcgta gtcaccagat
    46801 ttaaaaaaag attcgacagc tagtcagaag tgcctaatag ccactaagaa agcgttgaca
    46861 aaagcatttg ctttcgataa tataaagaaa acgatacaac ttggatagtg attgcctgat
    46921 gcaagctaaa cctgatgagt ctcccatggt ttcatggacg gctttttggg tttttctttt
    46981 tgttttggat acagccctat acatcatgga aaggagcaaa acatgctgat tgagaaagta
    47041 ctgaataaca acgtcgtaat aaccagggat gaaagaaatc aggaaatgat cgtgatggga
    47101 aaaggtttgg cattcaaaaa gaaagtgggt gacccgattt ttgactcatg catcgaaaaa
    47161 aaatttcagt tgacaaatga cgggctttca caacagttcc aagaattggc acaagcgatt
    47221 cctcttgagt acttagaaat ttcttgtgaa atcattgaat atacaaaaga ggctctacaa
    47281 gtccagttga atgattctgt gtatattgca ttgacggatc atttgtatac ggctatcgaa
    47341 cgtcacaaaa tgggaatatt tgtaccaaat gtattgctgt atgatatcaa acaactattt
    47401 cctaaagagt atgccatcgg gaaaaaaaca gtgaagaaaa tctcggataa ataccacatc
    47461 aagttatcag aagatgaagc cggatttatc gcattgcatt tagtcaatgc acaaggcatt
    47521 caaagccagc aagacaatac ctacctgttt actataacaa tacaggatat tctaaatatc
    47581 gtccgctatt actataagat tacatttgat gaagattcag tccatttttt tcgattcgtc
    47641 acacacttac gtttttttct gacacgcgtc ctagatggag aaaaatcaga agtgggagaa
    47701 gtttctgagg aattgtttca ggttattcaa aaaaaatata aggatacgtt tggttgcgtt
    47761 gagaaaatag cagacttttt agccgagacg ttcaactacc agatgtccac ggacgaaaaa
    47821 atgtatttaa cgatccatac tgcgcgttta gtgcatgaga atcgttgtaa ataaaaaaag
    47881 gaggataaat taacaagaac gtatgaaata agggtagtga cattcagttg gctaaacctt
    47941 ccactaataa attggaggga atagaaatgg gaaaatacca agaattagcg agaaaaatcg
    48001 tagaaaatgt cggcgggaag gaaaatatca atggtttgac acattgtatc acaaggcttc
    48061 gtttcaaatt aaaaaacgaa gaaaaagcaa atgatgagat cttgaaaaat atggacggta
    48121 ttgtaacggt aatgcgagcg ggagggcagt atcaagttgt cattgggaat catgtgccag
    48181 tcgtgtttga agaggttata aaagcaggaa accttacttt tgatgaggct gtttcaacag
    48241 aaaaaatgag accgtttgat atgcttattg atggaatatc gggctgtttc cagccattcc
    48301 ttgctatcct agctgctggc gggatgattc gtggactgac agcattcctt gtcttcttag
    48361 gcgcgtttga ccgcggttct ggcacatttg ttatgtttga taatatcggt gattctgtat
    48421 tccaatttat gcctgttatt atcggtttaa cagctgcccg taaatttaaa gtaaatgaat
    48481 tcgtagggat gttgcttggc gcagcattaa tgaatcctag cttgtcgctg gaagctttga
    48541 gtggtgcagc agaagcacca ctaacgacca tattttctgg cactattttt gaagcaccta
    48601 tttatcaaac agtattcggc attccctgga ttgcgcgtaa ctacgcttct tctgtcattc
    48661 ccattatctt tattgtgttg ttagctagcc aaattcagaa accaattaaa aagttagtac
    48721 ctgagatgat cgcgaatttc ttcgttccat tcttcaccgt tcttattaca atgcctttag
    48781 gttttttact cgttggacca gtattcacat tcgcaactga tattttaatg gctggatttg
    48841 aaacactttt agcactttcg ccagttattt atggagcaat cgtaggcttc ttctggcaaa
    48901 ttctggtgat gtttggtctc cattgggcaa tcgtaccaat gggattgatg caattttctg
    48961 tgaatggttg gcaaaatatt atgacacctg ttgcagtagt gtcttttgga caaactgcag
    49021 cacttaccgc actctacttt aagcttagaa atccaaaaga caaagcaatt gcaataccag
    49081 ccattgtttc tggtattgtg gggattacag agccagctat ttatgggttt acattaccac
    49141 gtaaaaaaat atttattttt acctgtgtcg gtggtgcgtt agggggcgcg tatagtgggt
    49201 taatgaattt aacttcttgg aatcaaggtg gactaggcat ctttacaatt cccaactata
    49261 ttagaccaga tggtgattta acagatgtga ttaatgtatt gattgggatc gccattgcga
    49321 tggtggtatc ctttacgctg acttttttct tttggaagga tgaagcaggt gaaacagatg
    49381 atatacagaa aaaatcaggt aaagaaattg taaaaacacc gatacaagga caaatcgctc
    49441 cactaaatgc agcaaaggat gcagcttttg cacaaggaac actaggtcga ggaatcttga
    49501 tctaccctga aaaaggagaa gtacgtgccc cttttgacgg aacagtcatg accctgttcc
    49561 cgacgaaaca ggcaattgga atggtttctg aaacagggct ggaattgctg attcatgtcg
    49621 gattggatac tgtgcagttg gaagggaaat attttgaaag cttagtgcag caaggataaa
    49681 gagtgaaaca aggcgatctg ttgctacgct tcgacaaaaa gaaaatcgaa aaggaaggat
    49741 acagtttaga aacacctgtg atcgtcacca attacacgga ttatttggat attttggaaa
    49801 accaagggga gacggtcggg ccagacgatg cacttatcac cgcactgacc tgaacggtta
    49861 ggtgaagaat ggactaggct taactattct ttttattcca cttctttatt ttcaaaattg
    49921 aaaggctctt tcatgatggc tgagctgata gggcgtttat cgaatttttg accgacagaa
    49981 attagatgga ctaaattctg ttgataattt tctgcaaaaa cacaactata taacacgtct
    50041 agaagataac aaattgatgt attgatcgta aaattaccaa tttttgaata cagtcgctcg
    50101 cgtgtcgtaa gtcgcaaagc ggctgtactc attgcagata gcgttgaatc accgatactg
    50161 gtcaaagcta aaattggaac atgattttgt ttcaatattt ctgcggtacg aaggatcaca
    50221 ttgttttcac ccgtataaga aatcagaatc ccgcacatat cactcgtgca attgtacgct
    50281 tcatagaatg attcaccaaa agtggtgaca atcgtgacat ccattttgat gcgcttcatt
    50341 ttcagcatga aatcttgaga aatcaaagta ttcgagttac tggcgaaaat cacgattttt
    50401 tttgcttgaa gcattagttg tttggctttt tgcagttggt catgatgaat gagagaaagt
    50461 gtatcatgaa tcgtcatctg ttctaaagaa gccattttat ttgcgatcgt cataataccg
    50521 tctgtggtgg aaaaaggaag attcgcatct acgtcttgaa aattcccttc aagataggct
    50581 gtttcagcta aaaaagcatt acgaaaactg acccagccat caaaacccat tttttttgct
    50641 acacggatga gtgtagaggg gtggacataa catcgctcag caatcgcttg gatggtcatt
    50701 tcgccaagtg ctggagaatc gcttaagaga aactggatca cttcattttc tgaaggagaa
    50761 aaggagattt ctttgatttt ttcacgtaat aacatgtaga taccttcttc ttattttttt
    50821 acgtaaatta taactttttt gaaaatgatt tgtaaacgga tttatactat ataacttaaa
    50881 atagacattt tttgacaaga tatttacaaa aatccactag aaaacagtaa attttgtaaa
    50941 tgttactgga aagaaacaga tttctattgt ttgttttgtt tacaaaaaag ataatgaaag
    51001 tgtaaaaaag taaaggagtg agaacatggc aaaaggaatc aaaatcgcta cgattggtgg
    51061 aggcagcagt tacacccccg agttgatgga aggatttatc aaaagatatg aggaattacc
    51121 gatacgagaa atctggctcg tagatgtaga agaaggaaaa gaaaagcttg agatcgttag
    51181 tcagatgtct cagcgtatgt gggatgcttc tccgtatgaa gtcaagatct atgcaactct
    51241 ggatcgggaa gaagcattga aagatgcgga ttttgttacg actcagtttc gtgtcggtca
    51301 attagatgca cgaatcaaag acgagcggat ccctagttat tatgggatga ttgggcaaga
    51361 aacaaatggt gctggcggga tattcaaagc ttttcgtacc gttccagtcg ttttggcaat
    51421 cgttgaggac atgaagcgtt tatgtccaaa tgcttggctg atcaatttcg cgaacccaag
    51481 tgggatggtg acagaagcag ttatcagata tggcaaatgg gataaagtga ttggattatg
    51541 caatgtgcca gtgatggcga tgatgacaga accagcaatg cttggcaaga aaaaagaaga
    51601 gctgatctac aagtttgccg gtctaaatca tttccattgg cacaaagtag cagataataa
    51661 aggaaatgac cgcacggcag aattgattga tcgtttatac gatgaagaga atggattacc
    51721 gaaaaatatc tttgatatcc cgtttttcaa agaacaatta aaacaaatga acatgatccc
    51781 ttgtggctac caccgctatt actatcgtga agaagaaatg ctggaacatg ctttagaaga
    51841 atatcaaacg attggtacaa gagcgcagca agtgaaagaa acagaagcag agctatttga
    51901 attatacaaa gatccagaat tagaccataa acctgaacaa ttgcaaaaac gaggtggcgc
    51961 ttattattca gacgctgcct gtgaaacgat tgcttcaatc tatggaaata aagaaacaca
    52021 gatcgtggta tctacaaaga atgatggagc tgttcctgac ctgccggcag attgtgtagt
    52081 agaagtcact gcctatgttg gcgcacaagg agcgagaaat gtagcgtttg gttctcttcc
    52141 tgctgctgaa agaggctggt tgcaagtaat gaagaatatg gaattgctga cgatcgaagc
    52201 agctgtgact ggtgattatg ggacagcttt acaggcgttt acgatcaatc cacttatacg
    52261 atcaggaaag acagcaaaac ggatcatgga tgagttgttt attgcacacc agcagtattt
    52321 accgcaattc aaggagacaa tcagccgatt aaaagaagaa ggaatcgaag ttcaagatga
    52381 actggcaaga gaattatcag gtaatacaca tataatggag gaagtataat gggattcaga
    52441 aaagattttt tatggggcgg tgctacagca gccaatcaat gtgagggcgg ttatgatgaa
    52501 ggtggacgcg gactagcaaa cgtagatgtt gtgccaatcg gaaaagaccg ttttcctgtt
    52561 atcaccggaa agaaaaaaat gtttgaattt gatgaggatc atttttatcc agcaaaaatt
    52621 gcaatcgata tgtatcatcg ttataaagaa gatattgctt tgtttgcaga aatggggttc
    52681 aagacttatc gaatgtccat cgcctggagt cgtatttttc caatggggga tgagaaagag
    52741 ccgaatgaag ctggcttgaa attttatgag gatgccttta aagaatgcca aaagcacgga
    52801 attgagccac ttgtgacgat tacgcatttt gattgtccaa tgcatttgat caaagaatat
    52861 ggtgcgtggc gttccagaga actcgttggt ttttatgaaa atctgtgtcg agtcatcttc
    52921 aatcgctata aaggacttgt caaatattgg ctgacattca atgagatcaa tatgatcctt
    52981 catgcaccat tcatgggcgc agggctgtat tttgaaaaag gagaaaatga agaacaaatc
    53041 aaatatcaag cggcacatca tgagttggtt gcaagtgcca tcgcaacgaa gattgctcat
    53101 gaagtagatc cggagaacaa agtaggctgt atgctggcag caggagcata ttatccatac
    53161 acttgcaatc ctgaagatgt ttgggcttct agaaaatcag atcgagaaaa ttatttcttc
    53221 attgatgtcc agtcacgagg agaatatccc gcttatgcat tgaaagaaat ggagcgaaat
    53281 ggcattcaga tcgaaatgga accaggggat gccgcattgc tgaaagaaca tactgttgat
    53341 tttatctctt tttcttatta tgcttcccga gtttcgacta ccgacaacga actcttggaa
    53401 cagactgcag gaaatatctt tgcttctgtc aaaaatccat atctgcaagc aagtgaatgg
    53461 gggtggcaaa ttgatccatt aggcttgaga ataacgatga atgatattta tgatcgttat
    53521 caaaaaccat tgtttattgt agaaaacggc ttaggtgcag tcgatacgcc agatgaaaat
    53581 ggttatgtgg aagatgatta ccgaatcgat tacctggcag cgcatatcca ggcgatgaag
    53641 gatgcagtag aactagacgg agtcgatcta ttaggctata cgacttgggg atgtattgat
    53701 ttagtatcag ctggtaccgg tgagatgaag aaaaggtacg gattcattta tgtcgatcgt
    53761 gataaccaag gaaatggcac attagcccgt tcaaagaaaa aatcattcaa ctggtataaa
    53821 aaagtaattg attcaaatgg agaaaatctt tcgaacgatt gatcaatgat ttataaaagt
    53881 ctattgtttt tcagcggatt tttcgagtat aataaagcta ttcgagaaac gcaagcagaa
    53941 caatagactt tttttcgcat tggctgtaaa gtatgcttac ttgattaagt aaaggagaat
    54001 ctacatatgt atgatgtaat cgttattggc gcaggtcctg ctgggatgac tgctgcttta
    54061 tatgcttcac gttcaaactt atccgtattg atgatcgaac aaggtgcccc tggcggccaa
    54121 atgaacaata cggcagaaat cgaaaattat cctggattcg attcgatcat gggccccgat
    54181 ctagcttata agatgtatga aagtgtctca agatttggga cagaaaatgc ttatggaatc
    54241 gttcaagata tcaaggatca cggcagccat aaagaagtca tctgtgaaga taaaagttac
    54301 gaaggaaaaa cagtcattat cgcaacagga tgtatccacc gtaaattagg cgtacctggc
    54361 gaggaagaat ttgctggacg aggcgtttct tactgtgcag tctgtgatgg tgcgtttttc
    54421 cgtaacaaac gtctagtagt catcgggggt ggggactcag cagtagaaga agccatctat
    54481 ttgacacaat ttgcttctga agtagtgatc gtccaccgta gagatgaatt acgtgcacaa
    54541 aagatcatcc aagaccgtgc atttgcaaat gaaaaaattt cctttatgtg ggatacagtc
    54601 gttgacgaaa tcgttggaaa cgaaatggta gtgacaggtg tgaaagcacg taatgtcaaa
    54661 accggcaatg aatttgattt agcagcagac ggagtattca tctatgttgg actggatcca
    54721 ttaactgcac cttttagaga agcaggtttg acgaacgaag ctggctggat tccaacagac
    54781 aacgaaatga aaacgaatat gccaggcgtt tttgccatcg gagatgttcg tgaaaaagat
    54841 ttgcgacaaa tcactacagc tgttggtgac ggcggtattg ctggacaaca agtgtataaa
    54901 tacttggagt ctttagaaga aacaacagca taagtttaaa aagagtagaa gaacgggttc
    54961 aattgttctt ttactctttt ttttcgcgtg aaatttactg aatctgattt atgcgaacac
    55021 gtccaacacc ttttgataaa agaatccttt cttgatttaa gcgttttttg gtcctcatac
    55081 tttcatatct aataagtgaa tgctatactt attaagaacc atatttcaga aagaggtgtt
    55141 attttcatgt cttgggaaca agtgtatgaa caatgggtac atgaagaaaa tttagaagaa
    55201 aacttaaaaa aacaattaaa tgatctgggt gaagatcctg aaaaacttga agatgctttt
    55261 tatgcaccgt tggaattcgg tactgcaggt atgcggggaa tcttaggacc tgggatcaat
    55321 cgaatgaaca tctatacggt aagacaagca acagaaggac tagcacgttt catggataca
    55381 caaggtgaag aaacaaaacg ccgaggtgtc gctatcgctt atgactcacg ccatcagtca
    55441 ccagaatttg caatggaagc agccaaaaca ctagcacatc acaatatccc gtcttatgta
    55501 ttcgaaagtc tgcgtccaac accagagctt tcttttgcag ttcgtcattt gaagacgttt
    55561 gcgggaatca tggtaaccgc atctcacaac ccagcggctt acaatggata taaagtctac
    55621 ggagaagatg gcggacaaat gcctcctgca gacgcagatg cattgacgaa atatgtccgt
    55681 gaagtcagca atccgctaaa agtcgaagta ttatctgacg aagaagctaa acatagcggg
    55741 ttgatcacga tcatcggaga agaagtggac gctgcttatc tagaagaaat caaagcagtg
    55801 acgattgatc gtgaattggt tgaaacaatg gggaaagatt tgaaacttgt gtacacgcca
    55861 cttcatggaa cagggaaaat gttgggcgaa cgtgcgttga aacaagctgg attcgaacaa
    55921 ttcgtactag ttcccgaaca agctgtggca gatccagatt tcactacggt caaatcgcca
    55981 aatccagaag aacattcagc ttttgaatat gctatacgac ttggagaaaa agaaggagct
    56041 gacttgctga ttgcaacaga tcctgatgca gaccgtttag gcgcagcggt tcgtttgcca
    56101 gatggttctt atgaagtatt gactgggaac caaatcggag cattgtttgc tcaatatatt
    56161 ttggaagcac atcaatcaag aggcacttta ccagaaaacg cagcggtatt gaaatcaatc
    56221 gtttccagcg aattgcctac agcaattgcg gaacactacg gtgctaccat gttcaatgtg
    56281 ttgacagggt ttaaattcat tgctgaaaaa atccaacaat ttgaagaaga ccattcacat
    56341 acttttatgt ttggattcga agaaagttat ggttatttag ttaaaccttt tgttcgcgat
    56401 aaagacgcga tccaagcatt gcttttatta gcagaagtag cagcttacta taaaaaacaa
    56461 ggcaaaacgt tgtatgacgg cttgcaaacg atttttgaaa cctatggcta tttcgcagaa
    56521 aaaacgattt ctgtgacaat gagcggacaa gaaggttctg cgaaaatctc tgctttgatg
    56581 gaaaaattcc gtaaagaagc accgacagaa tttgccggag caaaagttat tcaaacagaa
    56641 gactttaaag aattgacgag aacagaccgt gaaggaaacg tagaaaaact aacaacaccg
    56701 ccatccgacg tattgaagta tacattggaa gaaaatggct ggattgctat ccgcccttca
    56761 ggaactgagc cgaaaatcaa gttttatatt ggtgtaaaag gaagttctac agaagacgca
    56821 gccgaaaaag tagcctctta tgaagcgatt atcaaaaaga tgacagaaga ataaaaaact
    56881 tgagactgat ggaaaaagtg gtaaacttta gaagtcagtc ttttttcaag ttggaggtga
    56941 atggattgcc agacacgcaa aaatcaaaag tagagaaagt cagtcaatta ttcaaaatgt
    57001 tgagtgatcc cactcgtctt aaaattctgc tatatctgaa agacggggaa caaaatgtga
    57061 cagcaatcac ccaagcagtg gaaatggagc agtctgctgt atcgcatcaa ctacgtttat
    57121 taagagaaaa tcatgtcgtc aagtctcatc gcgagggaaa agcgattttg tatagtcttg
    57181 atgattctca tgtactggat attttgaacc agacactcaa acatgtggaa catcaataac
    57241 gataggtgca aatagataaa cactggagtg tgacaacgaa gaaatttcgt tgtcacactc
    57301 cagtgttttt taagaaaaag acaaaaatga tcaatcgctt ttttctgttg tttcagttcc
    57361 ataataacta tgatcttcta ggtctaaagc attcaaaata agcgaagccg tttcttcaat
    57421 agataaagat gctacattga tcactacaca tcctagtttt tcataaagat cattcgcaaa
    57481 atcgagttca gctctaattt tttcgatatc ggaataagca gtatcagggt ttaatccgta
    57541 agagcgcatc cgttctttac ggatattatt taaaatatct gggttatttg ttagtcccac
    57601 gattttttta ggatcgatct cccaaagctg tttgggaata tgtgcttgtg ggatcaaagg
    57661 taaattggca acttttaaat ttttgttagc taaaaacaag ctcaaaggcg ttttggaagt
    57721 tcgggatacg cctagcaaaa cgacatctgc ttctaaaaaa ccacgaggat ctttcccatc
    57781 atcgtatttt acagcaaatt ccattgcttt gatccgtttg aaatagttct cattcaataa
    57841 atggagggca ccaggttgcc gaattggctt gataccagtt aaacgttcaa tttctgatat
    57901 cggtggcgtc atcacatcaa aactaaataa ttgatgttct tcacaaaaag aacgtgttat
    57961 ctcgatcagt tcttgattga ttaatgtatg caggacaagt gctttttctt ctaatgcatc
    58021 ttgcaatgcc tgccttaatg ttttttcatc tgtcacgaac gttctgcgga ataggttgaa
    58081 ctcaacggta ggatactgag ccatagtagc ttgcgctagt tttgtcgcag tttctccagc
    58141 agagtcggag atgacaaaaa aagtaacgat ttctgtagaa tcggaagtca tggataaaac
    58201 ctcacttgca ttttttttat gtttattata ccatactcta gaatgcgtac ttcgtaatca
    58261 ttttgatttg gagggataag tcatgaaaaa acagacattg atcgaacaat cattagaaac
    58321 attgaaaaat aacggtttta aatatactaa aaaaagagaa gcattgttaa cttatttagt
    58381 gaagcgtaac cgctacgtat ctgctaaaga agtttttgac tatatgaatc aggaattcaa
    58441 aggggtaagt tatgatacga tttaccggaa tctccatgat tttgcagaga tcgatttact
    58501 ggaagaaacc gatttaaatg gagaaatgaa gtttcgtttt cattgctgtc aggggaaaat
    58561 cggccatcac catcatttta tctgtacagt gtgcggaaca acgaaagaaa tccatatgtg
    58621 tccgatgaat tatttcgaag aacagctagg tggatgcacg atcgaagggc atagattcga
    58681 gattttcgga agatgtgaaa attgtcaata aggatttaaa taaaataaca tttgataatt
    58741 ttaaaaaaaa gcaagatttc cttgacggtc aaaacagcat tagatataat atttacagga
    58801 cagtcttgtt ttttgagata tatttcaata acaattacgg ttacttttta agctcggagg
    58861 gagggaatta acatgtcaaa aacagtcgtt cgcaaaaacg aatcacttga cgatgctctt
    58921 cgtcgcttca aacgttccgt gtcaaaagcg ggtactttac aagaatctcg taaacgtgaa
    58981 ttctacgaaa aaccaagtgt aagacgcaag aaaaaatctg aagcagctag aaaacgcaaa
    59041 aaattctagt tctgtgatga attggagttg gtagtgtgtc actactaagt agattaaacg
    59101 atgacatgaa agcagcgatg aaagcgaaag ataaggaatc tttacaagtc atccgaatga
    59161 tcaagtcatc tatacaaaac gagcagatta aagaaggtca cgacttgaca gaagaagaag
    59221 aactaacggt gttgtctcgt gaaatgaaac agcgacgtga ttctttgcat gagtttgaag
    59281 aagcaggacg tgacgattta gctgaaaaag taaaaagtga aattgtaata gtcgaaaaat
    59341 atatgccgga acaactttcc gacgaagaaa ttcgacaact tgttcaagaa gcaatcactc
    59401 aaactggtgc ttcatcaatg aaagaatttg gcaaagttat gggtgcaatt atgcctaaag
    59461 tcaaaggaaa agcagatgga aaccaagtga atgcgattgt gaaagaacta ttacaatctt
    59521 aattttatca tttaaactgc ggacagtgat tatccgcagt tttttgtgtt cgtaaaaaaa
    59581 gaactaaaaa acagctagaa gaaagaatct tattctt
//
LOCUS       DAPBBV010000013        57646 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.013, whole genome shotgun sequence.
ACCESSION   DAPBBV010000013 DAPBBV010000000
VERSION     DAPBBV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 57646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.013"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..135
                     /locus_tag="RD486_001008"
     CDS             <1..135
                     /locus_tag="RD486_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7662753.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLT
                     "
     gene            complement(191..2554)
                     /locus_tag="RD486_001009"
     CDS             complement(191..2554)
                     /locus_tag="RD486_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HDT7662754.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            3002..3223
                     /locus_tag="RD486_001010"
     CDS             3002..3223
                     /locus_tag="RD486_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7662755.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3331..3678)
                     /gene="rbfA"
                     /locus_tag="RD486_001011"
     CDS             complement(3331..3678)
                     /gene="rbfA"
                     /locus_tag="RD486_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDT7662756.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3705..6011)
                     /gene="infB"
                     /locus_tag="RD486_001012"
     CDS             complement(3705..6011)
                     /gene="infB"
                     /locus_tag="RD486_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDT7662757.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(6024..6335)
                     /locus_tag="RD486_001013"
     CDS             complement(6024..6335)
                     /locus_tag="RD486_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HDT7662758.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6332..6625)
                     /locus_tag="RD486_001014"
     CDS             complement(6332..6625)
                     /locus_tag="RD486_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDT7662759.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6647..7822)
                     /gene="nusA"
                     /locus_tag="RD486_001015"
     CDS             complement(6647..7822)
                     /gene="nusA"
                     /locus_tag="RD486_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDT7662760.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7846..8319)
                     /gene="rimP"
                     /locus_tag="RD486_001016"
     CDS             complement(7846..8319)
                     /gene="rimP"
                     /locus_tag="RD486_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDT7662761.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8463..12815)
                     /locus_tag="RD486_001017"
     CDS             complement(8463..12815)
                     /locus_tag="RD486_001017"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDT7662762.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(13027..14736)
                     /locus_tag="RD486_001018"
     CDS             complement(13027..14736)
                     /locus_tag="RD486_001018"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDT7662763.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14804..16072)
                     /gene="rseP"
                     /locus_tag="RD486_001019"
     CDS             complement(14804..16072)
                     /gene="rseP"
                     /locus_tag="RD486_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDT7662764.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16233..17033)
                     /locus_tag="RD486_001020"
     CDS             complement(16233..17033)
                     /locus_tag="RD486_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDT7662765.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(17030..17842)
                     /locus_tag="RD486_001021"
     CDS             complement(17030..17842)
                     /locus_tag="RD486_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDT7662766.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(18037..18594)
                     /gene="frr"
                     /locus_tag="RD486_001022"
     CDS             complement(18037..18594)
                     /gene="frr"
                     /locus_tag="RD486_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDT7662767.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18597..19319)
                     /locus_tag="RD486_001023"
     CDS             complement(18597..19319)
                     /locus_tag="RD486_001023"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDT7662768.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19455..20336)
                     /locus_tag="RD486_001024"
     CDS             complement(19455..20336)
                     /locus_tag="RD486_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDT7662769.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20435..21217)
                     /gene="rpsB"
                     /locus_tag="RD486_001025"
     CDS             complement(20435..21217)
                     /gene="rpsB"
                     /locus_tag="RD486_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDT7662770.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21576..22055
                     /locus_tag="RD486_001026"
     CDS             21576..22055
                     /locus_tag="RD486_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HDT7662771.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22272..23363
                     /gene="phnW"
                     /locus_tag="RD486_001027"
     CDS             22272..23363
                     /gene="phnW"
                     /locus_tag="RD486_001027"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDT7662772.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23356..24141
                     /locus_tag="RD486_001028"
     CDS             23356..24141
                     /locus_tag="RD486_001028"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HDT7662773.1"
                     /translation="MIKTVIYDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24487..26178)
                     /locus_tag="RD486_001029"
     CDS             complement(24487..26178)
                     /locus_tag="RD486_001029"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDT7662774.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26600..27547)
                     /gene="arcC"
                     /locus_tag="RD486_001030"
     CDS             complement(26600..27547)
                     /gene="arcC"
                     /locus_tag="RD486_001030"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDT7662775.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27662..28681)
                     /gene="argF"
                     /locus_tag="RD486_001031"
     CDS             complement(27662..28681)
                     /gene="argF"
                     /locus_tag="RD486_001031"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDT7662776.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28772..30001)
                     /gene="arcA"
                     /locus_tag="RD486_001032"
     CDS             complement(28772..30001)
                     /gene="arcA"
                     /locus_tag="RD486_001032"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HDT7662777.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30462..31163
                     /locus_tag="RD486_001033"
     CDS             30462..31163
                     /locus_tag="RD486_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7662778.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31735..32751)
                     /gene="tsaD"
                     /locus_tag="RD486_001034"
     CDS             complement(31735..32751)
                     /gene="tsaD"
                     /locus_tag="RD486_001034"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDT7662779.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKAFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32748..33212)
                     /gene="rimI"
                     /locus_tag="RD486_001035"
     CDS             complement(32748..33212)
                     /gene="rimI"
                     /locus_tag="RD486_001035"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDT7662780.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33219..33761)
                     /gene="rimI"
                     /locus_tag="RD486_001036"
     CDS             complement(33219..33761)
                     /gene="rimI"
                     /locus_tag="RD486_001036"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDT7662781.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33745..34467)
                     /gene="tsaB"
                     /locus_tag="RD486_001037"
     CDS             complement(33745..34467)
                     /gene="tsaB"
                     /locus_tag="RD486_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDT7662782.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34658..35638)
                     /locus_tag="RD486_001038"
     CDS             complement(34658..35638)
                     /locus_tag="RD486_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7662783.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35662..37146)
                     /gene="galT"
                     /locus_tag="RD486_001039"
     CDS             complement(35662..37146)
                     /gene="galT"
                     /locus_tag="RD486_001039"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HDT7662784.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37158..38147)
                     /gene="galE"
                     /locus_tag="RD486_001040"
     CDS             complement(37158..38147)
                     /gene="galE"
                     /locus_tag="RD486_001040"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDT7662785.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38396..38563
                     /locus_tag="RD486_001041"
     CDS             38396..38563
                     /locus_tag="RD486_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HDT7662786.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38625..40436)
                     /locus_tag="RD486_001042"
     CDS             complement(38625..40436)
                     /locus_tag="RD486_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HDT7662787.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40433..40798)
                     /locus_tag="RD486_001043"
     CDS             complement(40433..40798)
                     /locus_tag="RD486_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HDT7662788.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40961..41356)
                     /locus_tag="RD486_001044"
     CDS             complement(40961..41356)
                     /locus_tag="RD486_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7662789.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41374..42336)
                     /locus_tag="RD486_001045"
     CDS             complement(41374..42336)
                     /locus_tag="RD486_001045"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HDT7662790.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42336..42548)
                     /locus_tag="RD486_001046"
     CDS             complement(42336..42548)
                     /locus_tag="RD486_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HDT7662791.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42569..43267)
                     /locus_tag="RD486_001047"
     CDS             complement(42569..43267)
                     /locus_tag="RD486_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDT7662792.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43287..43829)
                     /locus_tag="RD486_001048"
     CDS             complement(43287..43829)
                     /locus_tag="RD486_001048"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDT7662793.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43961..44965)
                     /locus_tag="RD486_001049"
     CDS             complement(43961..44965)
                     /locus_tag="RD486_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDT7662794.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44962..45951)
                     /locus_tag="RD486_001050"
     CDS             complement(44962..45951)
                     /locus_tag="RD486_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDT7662795.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45948..46754)
                     /locus_tag="RD486_001051"
     CDS             complement(45948..46754)
                     /locus_tag="RD486_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662796.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46920..47876
                     /locus_tag="RD486_001052"
     CDS             46920..47876
                     /locus_tag="RD486_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7662797.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47953..48471)
                     /locus_tag="RD486_001053"
     CDS             complement(47953..48471)
                     /locus_tag="RD486_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7662798.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48559..48708)
                     /gene="rpmG"
                     /locus_tag="RD486_001054"
     CDS             complement(48559..48708)
                     /gene="rpmG"
                     /locus_tag="RD486_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7662799.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48936..49382
                     /locus_tag="RD486_001055"
     CDS             48936..49382
                     /locus_tag="RD486_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDT7662800.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49577..51472)
                     /gene="asnB"
                     /locus_tag="RD486_001056"
     CDS             complement(49577..51472)
                     /gene="asnB"
                     /locus_tag="RD486_001056"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDT7662801.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51797..52771)
                     /gene="bsh"
                     /locus_tag="RD486_001057"
     CDS             complement(51797..52771)
                     /gene="bsh"
                     /locus_tag="RD486_001057"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDT7662802.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(53107..53194)
                     /locus_tag="RD486_001058"
     tRNA            complement(53107..53194)
                     /locus_tag="RD486_001058"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53160..53162),aa:Ser,seq:cga)
     gene            complement(53339..53905)
                     /locus_tag="RD486_001059"
     CDS             complement(53339..53905)
                     /locus_tag="RD486_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7662803.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            54160..55491
                     /locus_tag="RD486_001060"
     CDS             54160..55491
                     /locus_tag="RD486_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HDT7662804.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            55457..55807
                     /locus_tag="RD486_001061"
     CDS             55457..55807
                     /locus_tag="RD486_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662805.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(55899..56318)
                     /locus_tag="RD486_001062"
     CDS             complement(55899..56318)
                     /locus_tag="RD486_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDT7662806.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(56319..56663)
                     /locus_tag="RD486_001063"
     CDS             complement(56319..56663)
                     /locus_tag="RD486_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDT7662807.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            57013..57609
                     /locus_tag="RD486_001064"
     CDS             57013..57609
                     /locus_tag="RD486_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7662808.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT        16229 a        12145 c        10068 g        19204 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctca cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga
      181 ttttatcatt ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa
      241 taccattttc acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa
      301 aatcttctgc ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat
      361 caagttcatt tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc
      421 catgaatcat taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat
      481 aaccgtggaa agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat
      541 cgctcaaccc acgcggatct tgacttggat gacgtaattt caataaatct acgacattga
      601 tgaaccgaat ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt
      661 ctaagttaga ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg
      721 tcgaagccca atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg
      781 agtaaaattg agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc
      841 ggaatgcttt atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga
      901 tgaactccgc cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc
      961 cattgtgatc ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt
     1021 ttcgccaaga aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt
     1081 caaccactcg caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt
     1141 acccttctaa gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag
     1201 atggcgaaag ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg
     1261 ttttgaaaac ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat
     1321 tttctggatt tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg
     1381 ctttaacgga gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa
     1441 gcggtcttgg atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag
     1501 taggcgcaat ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg
     1561 gttcatagga tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta
     1621 caggaatcgg tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt
     1681 ttggaccggt ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga
     1741 catctgttgc tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt
     1801 gatccatttt ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga
     1861 aaggctccca gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca
     1921 agatcgttgg gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat
     1981 ctatcactgg attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg
     2041 cttcaccatc accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga
     2101 ctgcatgtga aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg
     2161 gtgctgcatg agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc
     2221 ctgtctcatc ttccgttact tctggataga tctctgtgta acttccatct aaataagcat
     2281 tcgataccat gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat
     2341 atttattgat gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc
     2401 aatgaccgat tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt
     2461 tatctttaag ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca
     2521 ttttatcaaa gtattcttta ctagaataat ccatacataa cactcctttt cattattact
     2581 cttattctag cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg
     2641 gattttatat ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga
     2701 cgttttttac attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt
     2761 tcgctcctca tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa
     2821 aactggggct ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg
     2881 ttatctttgt caatatgtga attggtatcc cagctactat gctaatttct acagggatta
     2941 tccaaaattt ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa
     3001 cgtgattttt cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc
     3061 cactgatctt ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc
     3121 ttccgttatc ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa
     3181 gaaagtcgaa ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac
     3241 taaagtcatg gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc
     3301 tgatttcaca ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc
     3361 atcgatatgg ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt
     3421 ataaatactt agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc
     3481 atcttgtgct tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc
     3541 ttgctgtaag tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc
     3601 acggaccttt ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg
     3661 atcacggtag ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact
     3721 tcttccatga taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc
     3781 atcgcaccac attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga
     3841 cttgcaagtt ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct
     3901 ctacgaatat atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg
     3961 aaggtttcac gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc
     4021 cctttcatcg cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata
     4081 tcgacttctt cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg
     4141 atgataatag cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca
     4201 gctgaatgga cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc
     4261 agtgcttctg ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg
     4321 ccttctttca ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt
     4381 tccaataatg cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg
     4441 aagactacga aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc
     4501 gttgcaggtc ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt
     4561 ccgtaagtat taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt
     4621 aaggttgaca caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg
     4681 cgttgtgttg gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc
     4741 aattcttcga tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc
     4801 catgcttcag gaattaattc atactcactt aattcttgca taacatgctg aggatttgca
     4861 cctggtttat caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg
     4921 ttgattgctt caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg
     4981 atatctgtga tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta
     5041 tccaagaaag tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg
     5101 attccgccgg cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt
     5161 ttcccgtggt ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct
     5221 ggatcgactt cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt
     5281 tcttgtggtt ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct
     5341 tggttttgat tgaccatgac accaagcata aataattttt taatgatttc tgctggctca
     5401 cgatgaattt ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct
     5461 ggcaattcac ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct
     5521 tttttacctt ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta
     5581 ttgtttggtt tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga
     5641 cgattttggc tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga
     5701 ttcacttgac cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt
     5761 tgattgttcg ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg
     5821 cttgcttgtt gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc
     5881 ttctcatcac tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt
     5941 gctttttcca cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt
     6001 ttgttgccca tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat
     6061 ccggcatcca ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct
     6121 tcagaaaata gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt
     6181 cttgtattct cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt
     6241 tcagcaatgg tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg
     6301 agattcatgg ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt
     6361 tttggtgagt gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga
     6421 gtactcgatc gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga
     6481 catacgctcc tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg
     6541 aacgggtgat tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc
     6601 gtaaaggaat tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt
     6661 tttcttcgac cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg
     6721 actgaacgat tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat
     6781 aaaattccgt catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag
     6841 ctaaacgtgc attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga
     6901 caactgtgca ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat
     6961 tcaatgcatt tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt
     7021 cgccttttaa ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac
     7081 cgactgcatc gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt
     7141 cacgggcgat gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa
     7201 ataagcgacg caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg
     7261 tattttctac tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg
     7321 gcatttgatc ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac
     7381 gtttatcctg gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt
     7441 tataaataat cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt
     7501 gcgcagcgat ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct
     7561 catatgctgg attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca
     7621 cttcttccgt tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt
     7681 ccacttcgac gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt
     7741 ctaaagcatc gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg
     7801 catttaacat ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc
     7861 taagcgagct tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat
     7921 gcgtattttc aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt
     7981 ttcgccatct actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata
     8041 gtcgctttct tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc
     8101 ttgaggaatc ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa
     8161 ggcgcattct tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct
     8221 ttttccttct tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg
     8281 tgtcaccatt tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat
     8341 taagtgcgta attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc
     8401 attacctata agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat
     8461 gcttatagca tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca
     8521 ttgtcgttca tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct
     8581 ttggataaaa atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc
     8641 aaacttggga cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg
     8701 gcatccgatt tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg
     8761 gctaactcca gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc
     8821 gtgatttctt tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca
     8881 aagtcgtctg cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg
     8941 aaataagcga cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata
     9001 tatttgattt ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc
     9061 gatagatagg tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt
     9121 tccatgattt taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata
     9181 tcatcacgac agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc
     9241 gcatttccta accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca
     9301 aaagttgtag gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga
     9361 atacctaatg tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga
     9421 ccggcaaata tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct
     9481 gataaatctt gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc
     9541 aatacattat cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga
     9601 tcgtctgctg gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg
     9661 atgatccccc ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat
     9721 ctgtcgactt ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag
     9781 ccatatgctg ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg
     9841 ccaaacaata ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa
     9901 tcaatatcgg gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga
     9961 ccgtctttgt ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca
    10021 gaaccatacg taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga
    10081 ggggctaatg gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca
    10141 gagccacgtg aacctactag atagccatct tcattacttt tatgcactag tttttgggcg
    10201 atcagataaa taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt
    10261 ttttgaatga tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat
    10321 tctgatattt catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga
    10381 atcacttctt cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct
    10441 gtttcttccc ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca
    10501 tccggcaaac tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt
    10561 cggtaaatgg catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta
    10621 tccaaacttt ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt
    10681 tttaccaatt cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa
    10741 tcatagaatt ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat
    10801 atttctccct tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg
    10861 gagcgtggta ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg
    10921 aacaaatctt tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc
    10981 cttttgtaag aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta
    11041 tgattgtcca ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca
    11101 tagattgctc ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat
    11161 ccgaaacgtt tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga
    11221 ttggccgctt caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa
    11281 gccgcgttgt gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact
    11341 tcttcttccg actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt
    11401 gttcgtgaca atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct
    11461 ttatacattt tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc
    11521 gtttccacgt caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa
    11581 gcaattggga caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct
    11641 gctttttttc cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg
    11701 gcgatagctc ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt
    11761 gcatccatcg tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga
    11821 gcataatctt tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa
    11881 tcacggacaa acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg
    11941 atcgcatcaa atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat
    12001 gaagtataat ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact
    12061 tctttgtcga atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc
    12121 attggtgtcg ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga
    12181 gctggcgatt gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct
    12241 gcttgcttca taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca
    12301 cgttccgctt gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg
    12361 acgaacaact cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta
    12421 ctgtcgattg gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact
    12481 tgctgtgcta gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc
    12541 aagagctgtt catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata
    12601 tctttaaaag cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt
    12661 ttggaaaaat gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc
    12721 atttcaccag cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc
    12781 aacagttttt caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa
    12841 acaatgcaat tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt
    12901 tttctgagtt ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa
    12961 agcgaatcat cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa
    13021 cgcttattat tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg
    13081 tacttcaacc atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt
    13141 tttaccgaca gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc
    13201 tgcgcgttca tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc
    13261 tagttcattc gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag
    13321 atcaaatggc gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac
    13381 gattgctgat aataaacgac ttacaccgat accataacag cccataatca caaatttttc
    13441 tcgtccattt tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt
    13501 gaatatatgt ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga
    13561 aggatctcct tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt
    13621 tggattcaca tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa
    13681 atcttggaca taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac
    13741 agaaccaaac tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa
    13801 gtcagcagat aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa
    13861 aacaaggaca ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc
    13921 aacagaaaag aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc
    13981 caattcaagc tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa
    14041 gtttgcagca taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat
    14101 cgccatgaat tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg
    14161 aaattctaag ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt
    14221 ctcgtccaaa ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct
    14281 tccgcgaagc aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata
    14341 aagatttaaa ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt
    14401 ttcttcgtga gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa
    14461 gtttggtcca tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc
    14521 aggcatcagc atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag
    14581 tttttccaat acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg
    14641 gatatatcca gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc
    14701 gcgtaatgtt ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca
    14761 aaatagttat cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt
    14821 gaatatcgtt ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg
    14881 tcaatattcc ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca
    14941 agactaattt cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca
    15001 ttgaaagaag cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag
    15061 acaattggta catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg
    15121 atcctaaggc tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga
    15181 tcttatccat aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc
    15241 catttgactc tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga
    15301 tcttaaagtc taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg
    15361 aatggatttc ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg
    15421 ccgcagctcc attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac
    15481 cttgcataaa tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc
    15541 cagcaaagtt ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg
    15601 gcgcaattct gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt
    15661 aggttactac ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta
    15721 aatcataacg gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat
    15781 ttatcttctc tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca
    15841 tttctgtttc atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc
    15901 gaagcgtata tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga
    15961 tagcaaattc gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat
    16021 gaacaatcac taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt
    16081 tctcctttac ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc
    16141 atagtatacc aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt
    16201 atgaaattca caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata
    16261 ggaaatacaa acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata
    16321 tttcccgagt ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat
    16381 tgtccgactg ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat
    16441 agttcttttg ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata
    16501 ccaccgagcg caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga
    16561 ccataacgtc gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca
    16621 aatatcaaaa cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc
    16681 acatacaagc tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa
    16741 ataactgatg ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca
    16801 ttctctggaa gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg
    16861 gcggataaaa ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa
    16921 actcctacta ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata
    16981 atcggaataa acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat
    17041 cccctttctc atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag
    17101 aggcgattgc ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat
    17161 acagctcact atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg
    17221 tacggatcat cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct
    17281 tagcaatcaa ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg
    17341 caatttcttg gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca
    17401 ataccattcc agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat
    17461 gttctggcaa tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt
    17521 ctggtacgaa cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt
    17581 ttggtcgctt ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc
    17641 ttgatgcttt ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc
    17701 gtggcaaacg acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct
    17761 gaggaattgg tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt
    17821 tttgcggaaa aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt
    17881 aagtattata gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa
    17941 ctgaataatt ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga
    18001 agcggaatga tccgcccctc tgtttttatg attttattaa acttccaata attctttttc
    18061 tttatcagca gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc
    18121 tttttctaat ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata
    18181 ttcatcgatc gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt
    18241 tttcacatct ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg
    18301 aatgacattt ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc
    18361 aacatcttga agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat
    18421 ttggattgat gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg
    18481 gtccaaaagg ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt
    18541 ttgtgctgct tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat
    18601 ttccccctta cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt
    18661 tcatttaaat tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt
    18721 gaatccatga cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt
    18781 actgcatttg catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc
    18841 atcaggataa catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag
    18901 aagtacgggt tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt
    18961 tctgctttac ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg
    19021 cgtgtcggta cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta
    19081 gctaacatac ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt
    19141 ccgcgccaga tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact
    19201 tctttgattt cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc
    19261 ccagctaaag cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg
    19321 ttcattcctc caatattttc tattgccatt ttaccatact tagatgattt cgacactcta
    19381 agactggttt ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct
    19441 gttattcaac agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg
    19501 cgtttttcga taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt
    19561 gatgcaacgt atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa
    19621 gcgatttctg ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct
    19681 ggtttgcctt cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct
    19741 tctggaattt gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg
    19801 tctcttgcaa ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg
    19861 cccatatgca agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga
    19921 cggaagctga ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta
    19981 cctttatctg ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca
    20041 agttctgcaa tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt
    20101 tctgagttta cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct
    20161 tcagctgcaa tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga
    20221 tcaactgctt tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt
    20281 cctacgccag tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt
    20341 aactcctcct gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt
    20401 cgcccagcct ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt
    20461 caacaacatc tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt
    20521 caactacttg atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa
    20581 tcaatttaac ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg
    20641 gatcgcagtt tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa
    20701 cagcaatacg ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat
    20761 cagcgatacc gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt
    20821 cttttttagg tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac
    20881 ggctgatacg tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt
    20941 taacgaagta ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt
    21001 ttgtacctac gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag
    21061 ctgcatctac taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg
    21121 tgaagatata tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc
    21181 cggcttctag taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt
    21241 tatttttcct cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa
    21301 tccaataaga atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa
    21361 gatccgtatc gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag
    21421 ataaaaagaa ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca
    21481 taaaataatt ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat
    21541 gatacatgtg aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc
    21601 tgattaaaca agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac
    21661 ttgggcatta tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa
    21721 aaatcgtgaa ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag
    21781 gaactcctga gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg
    21841 tattgaaagt cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc
    21901 atttatttgc atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg
    21961 gattcgatac gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat
    22021 ttcttcacca tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga
    22081 atgcgtgttt ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa
    22141 aaatacatca ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat
    22201 ttatattgga tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga
    22261 aaggaaatca tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga
    22321 aaaatgctat gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat
    22381 ggataagaaa aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct
    22441 taatgcaagg tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag
    22501 aagatactgt actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg
    22561 aatgtctgaa actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc
    22621 atgtgattac acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata
    22681 gcgagactac ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa
    22741 aagatctttt gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag
    22801 ccgaactagg gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag
    22861 gcttttcttt tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa
    22921 gtttgtcact tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc
    22981 gtttcacttc ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg
    23041 cagaaggagg aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac
    23101 aaaaaatgac agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca
    23161 cctcttttct ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa
    23221 agcaaaacgg atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg
    23281 gaaatattgg cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact
    23341 ataaggagaa cgttaatgat taaaactgta atttatgatt gggcaggaac aactgtggac
    23401 tttggctgta tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa
    23461 ctgactgaca aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag
    23521 cttctttccc tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag
    23581 gaaaaagagg tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc
    23641 aagcattcta ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg
    23701 atcaatattg gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc
    23761 gcaaaaaaag aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat
    23821 ggtcgaccgt ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt
    23881 gatgaagtaa tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga
    23941 gtgttgacag taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac
    24001 caaaaattag agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa
    24061 caagctggcg ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac
    24121 gctgacaaga atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg
    24181 catcaagtaa taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc
    24241 ttattaccgc agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga
    24301 cacgactttt gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc
    24361 cactaaacgg tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga
    24421 aaagctattt tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc
    24481 tttttcttac atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa
    24541 tacagtcact gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat
    24601 cttcgtatga gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat
    24661 cactgacggt tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa
    24721 tttaaccact tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac
    24781 aaatcctgct ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc
    24841 agtttctcct tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc
    24901 gtttttcaaa tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt
    24961 gttttccaaa tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt
    25021 taatacttct tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg
    25081 cgtgatcaaa ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt
    25141 caagacagct ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga
    25201 ttgtttgaag tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta
    25261 tagtgtcgca ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc
    25321 aacgatctct gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat
    25381 ttcatccatc ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag
    25441 cagatcatag attttattga attctttcat cgattcatca cggaaccatt gccataattg
    25501 aatagcctct tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa
    25561 ttctggttct gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat
    25621 tggttctgct ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc
    25681 aaactgtgtt ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc
    25741 cataatgaaa ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg
    25801 tttggcaata ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct
    25861 atccccataa tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc
    25921 tttattcatg aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga
    25981 atcgattttt tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc
    26041 taatgaaaag gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa
    26101 ttgttcgact tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac
    26161 aagatcttta ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa
    26221 aaatctctag cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac
    26281 cactccaatt gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt
    26341 taaaacagaa ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc
    26401 cgaattcgct agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt
    26461 aaactttctt gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa
    26521 caatccagat ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa
    26581 atacgaaaga cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa
    26641 gattctcgat attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa
    26701 atgcaatagc tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa
    26761 tgtattgttt catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt
    26821 aattgacata cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt
    26881 cggctaattt ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag
    26941 tagctgtttc tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat
    27001 cgaccagcgt ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta
    27061 cttttctcca tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt
    27121 gttctttggc ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg
    27181 aaggatcatt ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc
    27241 ctttttcctt cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg
    27301 tcattgcaac acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct
    27361 gctgaatcaa taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc
    27421 cttgttcgat aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt
    27481 ttgcacttgc atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt
    27541 tggccatttc attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc
    27601 agcgttttgt gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg
    27661 cttaaacgcg agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt
    27721 gcatacgatt ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg
    27781 ttacttccat ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg
    27841 tatcatggaa agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt
    27901 ctaccatttc catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat
    27961 cttcttcacc cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt
    28021 tatcaacatc gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca
    28081 ttttgacgat ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc
    28141 ctaaaattgc acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt
    28201 aagcaacagt gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga
    28261 tcatttgtgt tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt
    28321 ctgctagttc ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac
    28381 gacctagtac tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg
    28441 cacctagata ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag
    28501 tacgtgtaga tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg
    28561 ggataccacg ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt
    28621 cttcttttgt aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca
    28681 tattaaacat tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca
    28741 gctgacagta agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt
    28801 ggctcatgca gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca
    28861 ctttgatgcc atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta
    28921 caacacctgg agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa
    28981 cgatctcatc tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt
    29041 tcatcgtttc gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga
    29101 ttgtaaagac atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat
    29161 cgtgatctac cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt
    29221 tgattgctaa cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt
    29281 ctaaagcttt cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga
    29341 tcaattcgtc tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc
    29401 ctttatttgc aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac
    29461 gacgtgcttc aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt
    29521 cgcgtgtaaa gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg
    29581 acagatcgta tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga
    29641 ttttatctac catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta
    29701 cagcattcga tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat
    29761 tgcctgcgtc aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat
    29821 tttgcaatgt ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat
    29881 catcgaacaa cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc
    29941 ttttcagtaa aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca
    30001 tgttgtgttg cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact
    30061 ttcataattt tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat
    30121 aattaaacgt ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt
    30181 caaaaaaata tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat
    30241 tagcgttgtt agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct
    30301 tcaaaacaaa ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta
    30361 aagtattaaa acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa
    30421 gtgacaataa atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg
    30481 attttcactt ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt
    30541 tccaacagat caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg
    30601 acgatggtga tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac
    30661 gttatgatga aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc
    30721 ctatgtcagg aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata
    30781 ttgaaacatt ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac
    30841 agttgatcta tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc
    30901 aaatcggatt gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag
    30961 aagaattggg cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa
    31021 aagaattagc agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac
    31081 tacgtgattc cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta
    31141 ctactccagc tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca
    31201 gggtcactgc ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg
    31261 ggcaagactc aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa
    31321 aatactgata gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata
    31381 ttcctcgaca ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata
    31441 agctgtaaaa aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt
    31501 gtgtacctgt caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt
    31561 ttgaaattgt tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg
    31621 gcgttcaaaa gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg
    31681 tttttcctgg gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc
    31741 agataaaacc aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat
    31801 ttccacatgt gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg
    31861 aatcactagt tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa
    31921 cccttgattg gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca
    31981 agctcgaagt gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa
    32041 atcatttttg tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc
    32101 actttttaat ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa
    32161 atggtaatta tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga
    32221 aagacctaat actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc
    32281 cccaatgatt tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct
    32341 aacaagaagt gccatcaatg gaaactggaa tgctttaacc agacgggctg catagatatg
    32401 ccctgccata tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc
    32461 tgcagaaata ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc
    32521 cgataaatct tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat
    32581 ttgttctacg tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact
    32641 gtttatttga gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac
    32701 actcgtttca tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc
    32761 tccgttttta actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat
    32821 ttccgtttac ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta
    32881 gatagacgta cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat
    32941 tgtaacaaat gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg
    33001 atctcgactt catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca
    33061 actaaaagca gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc
    33121 caaggtgaac catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac
    33181 gcttcatcaa aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt
    33241 atcatatcca acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct
    33301 tgaaaaccta acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat
    33361 gacatcgtct cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa
    33421 ccgattcgtt tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa
    33481 ccgaacgctc ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat
    33541 agatgaggaa gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg
    33601 ccattataga cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct
    33661 cttagtacgt aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct
    33721 tgaaaaaagc ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt
    33781 gtgcgtctcc aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc
    33841 ttgtttctct gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg
    33901 aatatcccat gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata
    33961 gaagaatttg tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg
    34021 tgtgaacaaa tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc
    34081 tttccagcgg tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat
    34141 aattttatcc acaccgatgc aattagccgc gatggttttc agactagata ctcctactag
    34201 ctctttatct aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt
    34261 ataagaaccg ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag
    34321 atctgcaaac aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt
    34381 tgtttgtatt tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt
    34441 tgcagtatct attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc
    34501 ttccattgta gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca
    34561 atgatacatg attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct
    34621 gcggtatcac ttcatttccc cacagctttt ccatctttta tttcgttgat tctcgaataa
    34681 tcaactctgt ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa
    34741 gaatcgtctc cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagag
    34801 agggcgttac atatttcgct acactgacat cattgaaacc catcacagaa atatcttctg
    34861 gtaccactaa acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag
    34921 ctgcaaaaag cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat
    34981 atcctgactc gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg
    35041 ccaaaacttg ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg
    35101 tatattctgt tccagcaagc atagcgatat gttgcgcttt atgggagaca aaatgttcaa
    35161 tgactttttg aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc
    35221 cgtcagaatc taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt
    35281 cgtcgaattt tcctagtgcg atcgttccat ctgtcggaag atcactaatg gaatcccacg
    35341 tttctttcaa taaagtaacg tttgcttctt ctgccttttt ttcgattcct agacgaatag
    35401 ataaataata aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg
    35461 tttgcttagt atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt
    35521 caaaaatttt ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc
    35581 ttgaaacagt agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt
    35641 gtctctcctc cttttttacg tttataaaat tgcagtaaat cgttcaaacg ctgcctgtcc
    35701 tttttcatct cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac
    35761 agatttttgt acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa
    35821 ttgttctgcc cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg
    35881 ctctacttct actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc
    35941 gatcaaccca atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc
    36001 atcaggatgt tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt
    36061 gtcccttctt cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc
    36121 tctgatagat actgtttcat ccgaatatgc tttccacttt tccaatactg agttagctgc
    36181 ttcaatcaac aattttttct ctgttgattg caaacggatc acagacatcg gccatttcac
    36241 gactcctgcg atgacttgcg gataatctgc tagtttgata agtttttcta tcggtgcttt
    36301 tgccatagga aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc
    36361 aacaatcggc aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg
    36421 aagcagtcta gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat
    36481 gatcgaatgt tcattgtaat aagcataagg agaatattgg aatccccagc tttcaccgtc
    36541 tagattcatt cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata
    36601 tccttcgttt tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc
    36661 tgctgcgatt tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc
    36721 accatactcc gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta
    36781 gtcatttttc ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata
    36841 gtgctgtgca aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg
    36901 cgcttcaaaa atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt
    36961 agcgacaagc tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct
    37021 ttctagagca tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat
    37081 ttccatccat ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat
    37141 tgacatatct cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat
    37201 gctgttttga taattgcttt gatatctgtg tattcaggtt tccaacccag aacctctctc
    37261 gctttttcac ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct
    37321 gctggaattt cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat
    37381 cctttgctgc tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa
    37441 gctaaaatat gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca
    37501 tctggtgtat cataatcgtc tccataaaca gccaatgctt ttctttgacc aagagctact
    37561 tgtaaaatga ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct
    37621 gcttttgctc cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg
    37681 tcacaccact tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga
    37741 ttagctggtg tatcttctgt gattggagac tcttttggtt ctccgtaagt tgctgcagta
    37801 gaagagaaca cgattttatt cacattgaac tcgtgcatga cttcaagtaa gatttgcata
    37861 ccgtatacgt tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag
    37921 cttgcagcaa aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat
    37981 tctttatccc ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga
    38041 cctgtgagca aattatctac cacagctact tgatacccct tttgaactag ctggtctaca
    38101 gcgtgcgaac cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct
    38161 ttgattagta aaattgtgtt tgttgattat atataattta aaaaaacgaa gtttactttt
    38221 atggtgaaaa caaacaaagt aaaatttcgt aaattcatat ggtaaattta taataaaaca
    38281 tttagtaaac attttcaagg attttttgca aaggtttaca aacaaacgta aaactagcct
    38341 ttttttctct tttgttccat aatagatata acaaataata aatgaggtgg attcaatgaa
    38401 aaaatttgta tctggaatat tagtaggaag tctggcaaca gccgctgccg ttgctggttt
    38461 ggtcgcttct gtgaaaaaaa cagtgatcga tccaattgac gaaaaagaag caatgatcga
    38521 agaaaaccgt aaaaaagcaa tgcgcaaacg cgtttctcgt taataattat ttaaaaacac
    38581 gcatgaagac ttgtgaaaga acagataagt catcatgcgt atttttattt gtcagtcaat
    38641 ataagttgtg ctattttatc tgcctgtctc agattccatg gatctgtata aggtctagct
    38701 actgctgcag ttagccaatc cacaccttca acaggtattc catagcaata aaagtcagac
    38761 tggatttccc ctgaagcatc aatcacgcga ttcgtacctc gctcaacatc tatagcttct
    38821 gaatgataac ttcctgtatt atctgaaaat gaaaaagggc gaacaagttt gttttccttc
    38881 aaatttttta tgacaggatt acttgaacga gaaaagcttg tttgtggcaa tcgagcttca
    38941 atcaaatagc gactgctgat ttctttatct tgtagagaaa taacatagcg gttgtgcttt
    39001 tgctgaatat caaatggcgg ttcgaacaaa tgaaaaatac ccgcatctat cagtgctgct
    39061 aattctttcg tccgaatgac tggcggaccg atcgttaaaa agctatttag atgagtaaac
    39121 catccccata gtatttcttt gtattccttt gcagaaaaaa cgtgccattc aatagcctgc
    39181 cggattggat cacgccagtc ttttaatgca tcaaatgttg aagcaaatgc tcctgtgcaa
    39241 ttgccttttt ccgcttcttt tatctgccct tcaataaatg ctcggctagc ttctgcaaag
    39301 gactcatcct gataggtaag aggaatttct aaatacgacc aatcccatct ataagggatt
    39361 agtgctggat gctttccgag acactcctct gaagagaggg agagaaaatc atgctcaaaa
    39421 tttttctttg gaatcggcaa atgatattct tcgatgattt tcttgtaata aaacaactca
    39481 acgtcttttt tcagatagtc aaaaaatgtt tcgccagtca aaaatcccga ctgatgccat
    39541 tgctccaggt tttcttttgt tagtaaccgt ggccatgcca ttgatccgcc ttgcttttgg
    39601 tttcttcctc gagggtaata agggagcccc cttcttgatc cactgtatac aatcggttcc
    39661 ttgcctgatg gatgatagac aagttttcct ttttcgttct cgaagcgccc ttctcttgat
    39721 actgtaaaca atccgacata atcaaaaaaa cttaagccta gacctcttaa aaagacattt
    39781 tctttaggcg gtatcttcga aagatcgaca tctgcaggat tagaaggaag ctgatacagt
    39841 aaatcatttt tctttgcgta gtctacccac actctttctt cttctgtctc atcattttcc
    39901 cagtgaccgc ttgctaaaac aagctgatcg atagaatagc tttgctgatc tgtctgtaaa
    39961 agataaccat cttttctttt gctgactttt tttactaaag aataaacaaa ctgaatagaa
    40021 gctggaaatt cttcttgcaa ctttgagaaa aaccagcgtt gatagagtcc gtataaacat
    40081 cgagtagatt gctgatcttt ttccagacga ttgatttctt ctataattag ttgcttattt
    40141 ttggttaccg tctgttcgat ataatctgta gcaggtcctt tactccattg aaacaagttg
    40201 ggtccctgtg ttaccaatcc tccactggac aatgtttcat ctgtaaaaag cgtcacttgt
    40261 tgagaaacag aattcattaa taactccggt ggctgattca accgccaaac tcgacctcca
    40321 ggaccattgg gatcgaaaag aaaaagttca agagaatgtc tgtcctgatt attatggaga
    40381 atcctttctg ctatacttaa tcctctaggt ccggcaccaa tgatccctat tttcatttgc
    40441 atgcctccat ttcgataaat tttttcaata aaacagcatg gttctgatgt tcattttttg
    40501 caccataaac aaaagtaatg actggatgtt ctttcataag ttgactgagt ttaaaaatag
    40561 cttgcttctt ttcttcttcg aaaatcaatt cttgctggta tttctttgca aatgaagcaa
    40621 atcgttctgg tacatggtca aaagttttgc gtgcttcatt actaggtgca atttctttca
    40681 accacagatc taactgcgct ttttcttttg aaattcctcg tggccagaac ctatccacga
    40741 gtattctata gccatcctct ttttcagcat caaggtaaac acgttttaat ttgatcatag
    40801 ttgtttcctt ctttctgcct tttcgcttag cttatatatg tagataatag cacaaaataa
    40861 aaaaaatgaa cggcacaact atccattgcg ccgttcatgt gatcttggtc aaaatctaat
    40921 gattgattcg gtttttaaag ctgtcataca atcatctgtt ttatactttt ttacttttga
    40981 tttttccaga ccatccgtca tatccaccct taagtaaata aatctcttga taacctgctt
    41041 tacgtaattt atttgctgta cggatgctca agcttttctt ttgatcgtaa atatagacag
    41101 gctggtcttt tcgaatagat cctaatgaat ctttcaaaac agtgtaaggg atgtttcttg
    41161 cacctaaaat atgcccagca tcaaacacat ctttttcgcg aacatcgatt acttgtgctt
    41221 ttctcattcc ttctcgaaat tcttcttctg tcaaagtcgt tgctgaacgc ttggccatta
    41281 ctcgtagata gacttcccaa aagatgattg caagcacaat caatagcaaa atgatattaa
    41341 ttacccataa aaccatgtaa tgcctccgtt tttttaagca aatttcaagg ctaatgaggc
    41401 agcaccaatg acaccagctt cattaccaag ctctgctaat ttgatttttg ttgattctct
    41461 tacttgcggg aaagtaaatt ctttaaaata tttctctaca cggctacgta aaaattctcc
    41521 tgctgccgat actcctccac ctaacacaat acttgacgga ttcaatgtat tccccaagtt
    41581 ggcgcaagct aaacctaagt agaagcatac gcgatcaaca accatcaatg caaacggatc
    41641 gtcttcttga gccatttcaa agatatcttt acttgttact tcttcaccgt tgtctaacat
    41701 tgctttcagt tttgaatctc ctgcgtattc ttctgccaag taacgaccta gacgtaccac
    41761 accagtagcg ctagacacag tttctaaaca tccgcgttta ccgcaagtac attcgaaccc
    41821 ttcaggatcc acagtgatat ggccgatctc tccgcctgct ccgctcacgc cgtgaatcaa
    41881 atttccgcca gcaacgatac caccgccaac acctgttcct agagtaacga atacaacgtc
    41941 tggatcgttt tctccagcac ctttccatcg ttcacctaaa gcagcaacat tcgcatcatt
    42001 atcgatagcg aatttgattc ctgttcctgc ctcgatcagt tttttcacaa attgaacttc
    42061 tgtccagttt aagttatacg caccaataac cgttccagct tcgctgtcca cgcttcctgg
    42121 ggtacccatg ccgattccga taaagtcttc ggctttcata ttatataaat tcaaacgatg
    42181 gttgattgat tcaatgattt caggaacgat atgcttacca tcatccaaaa tattggtatc
    42241 gatgctccat ttttgttgaa tctctccttc tggtgttaaa attgcaaatt ttgctgttgt
    42301 tccacctaaa tcaatcccaa taatcttctt gtccattaca aatttccttt ctttcggctt
    42361 tcttcaattc ggtgctctct ttttaatatg cgccacgctg tcatgtatgt atcatgatca
    42421 atcaaacggc tatcatacag attacgcaat tcgatagtca ttaattcaat gtcatagatg
    42481 cgtgcaccca catagataaa gatgccaaat tttttgaaca gctgctgtac atcatataag
    42541 ctctccatct ttaagcactt ccttcatatt atacaagtaa accatatttt tttaaaccca
    42601 gtaaaataca tattacaaaa agaaatacaa aaactagtgt agaaagaatc ctttggtgta
    42661 tcgaatagct tgtctgttgt ttcggtagac ccaaaacatt ccctaacact aatccgccaa
    42721 ttagcccacc gacatgtccc caaacatcta cagaggtatc cagaagacca aaaacaaatg
    42781 tcaacacaat aaataaaaga aaatgtctga ctagctgctg gatcgctggg ttatgtttaa
    42841 aatgaaaccc taagataaac aacgcaccga acaaaccgaa tatcgaagta ctcgcaccac
    42901 cagacagaac attcgcttcg ttaaaagcaa agcttgctgt atttcccatt atcccgctga
    42961 acatataaat caagaaaaaa cgccaatggc catagattgc ctcgatttgc tgccccataa
    43021 aatacagtat cagtgagttc attacgaaat gcatcagtcc aaaatggatg aagattggtg
    43081 tcactaaacg ccaccattca ttgaagtgaa caagataagg accatacatt ccggcataat
    43141 aagggatctc aagtcgcgga aataattcca tcatgaggaa gaccgctgtc tgtatcccta
    43201 aaaaagcata ggtccataac ggtcgtctta accatgcacg caattttatt tgctgttgat
    43261 aattcatgaa aacctcccat ttcattttag tcaataaaca attgttggat cttctgatca
    43321 aagctctccg gttgccattg ttcattcaat tgttcacgaa aaacaaggct acatgttttt
    43381 ttatgaaaat tatttaaata ccggtcgtaa taaccaccgc caaaaccgat tcgataaccg
    43441 gctctattgt agataatacc tggtacaatg aggagatcga tcatctccgg caaatagagc
    43501 ttctctgatt gtggctcaag aacaccaaaa ctcgaacgta caagaacgga ctgttcatcc
    43561 atttcataaa acgccatctg acgtttcggc aaagttttag gtacaactat tttcttttgt
    43621 tctttttctg ctcgttggat aaccggctgt gtatccagtt caaattcatt cgataaagtc
    43681 gtccctatca cttttgctga cttccagtac tcgctggcga atagctgttt atagattcgc
    43741 tgttcttttt cctttttctt gccacttttg gccagatttt tcagcttttc gattcctttc
    43801 cggcgtaatc ttactttcaa ttggtccaaa aactcaccct tccttctctc ataaaatggt
    43861 ataggaaaaa aagaaaaata gcaatcgaac tttcaaataa atgcataaat agaataaaaa
    43921 gaagacctag aaatgattgg ccttcctttt ttaataaatt tcaactgttc agcgcgtgtt
    43981 tttgtctgat aaaaagtgca tacagaaaat atggcgcacc aaaaagggca atcaaaattc
    44041 ctgtaggtac ttccccactt ggtagaatca ctctagcaac catatctgca ctaagcagaa
    44101 aaatggaacc gaacaaaccg ctcagaacaa aggtccagtt attttcttta cgtacgacta
    44161 gcttcgcagc atgaggagct agtagtccta caaaagataa actacctgtc accgctacac
    44221 taccgcttgc caaagcaaca gctaacaaca aaaggatttt ttgactttta gccacgttaa
    44281 ggcctaatcc ttgcgcgcgt tcttgaccaa atgatagcaa tccaatcctc tgtgcataaa
    44341 gtcctcctag cggaattaag ataaccgccc atggaagcaa tgcccaaaca taaggccagc
    44401 tcgcacccca gattgatccc gctaaccatg cattcacaaa tccataattt tccttagata
    44461 attggatcgt gcatagcaat gttaatgcag aaaggccggc attaacggca ataccggaca
    44521 ataagattcg attcataccc aaaaagccat ttcgatcata ggccgcaaga tagacacagc
    44581 aagcagctaa aacaccacct agaaaggcta caactagcaa tagaaacggc agcgaatagt
    44641 gcgaaaagaa acctaaataa agcatcacta aaaatcctgc tccggcatta atgcccaata
    44701 tactagaatc tgccaattca tttcttgtta ctccttgcaa gatataacca gaaacgccaa
    44761 gacaagctcc tgctaataaa ctgatcagta atcgaggaac tcgaaattct ctaacaatca
    44821 gcgccaaaga agatgattct ttccctatga acgtggcaaa aagctgatcc aggtaaataa
    44881 aaggcgtacc aatcattaaa ctacctatag acaggatgac aagtacaaaa agcaagaaat
    44941 agaacgtcca atatattttt ttcaccgttg ttccctcctt acttgtatca gtaaaaacgg
    45001 aacgccaatc aatgcaatga ctaatccaaa aggtgtttca aaagggggat tgatcatcct
    45061 cgctgtaaaa tccgccaaca taaccaatcc accgccaact aaaaaagaga caggtagaac
    45121 ataacgatag tccgttccaa ccattccgcg aacaactggc ggaaccaaca gcccaataaa
    45181 tgaaacaggt ccgactaacg aaacggcaat ggctgctaac actgcaacta gacagaaaac
    45241 aatcaaccgc gttcgtttag gatgacttcc aagagctaat gcatgtgttt cactcaaatg
    45301 aatcaaagat attgcttttc ctaatgaaaa agaaaccaaa acagcaagta tatataaagg
    45361 aaacaatact gctaattgtt tccatgtgat attggcagct ccgcctacaa accaaaaagc
    45421 aagatcctgc tgcagattaa agaattgggt aagtgcttgg ctgatagcag taaaaaaaga
    45481 actaatagct acgccagcta aaatcagctg taaaggattc atgcccattt tcgaaaactg
    45541 caaaaaacca aatacgagca aagttacagc aaaagaacct gccaatgaca ttagaaacac
    45601 agaaaaatca gaagctttag gccaaaaagc aaaactaagg gccattgcca acgaagcacc
    45661 cgcgttgatt cctagtaagc ctgaatctgc taaaggattt cttgtcactc cttgcatcaa
    45721 tgcaccgctc aatgcaaaac aactccctac aagaaatgct cccgccacac gaggcaaacg
    45781 aatatttcgt atgatttggt gactttgttt tgatctatca aaatcaaaca acgcctgcca
    45841 aaaatctgct tttcccacag tcgctgcgcc atttgaaaga gcaacaaaaa aaataatcaa
    45901 aagaacaaaa cagaccaaaa gcaggagtct atttttcttc atagtcctca taattgatcc
    45961 tcctgctctt ttggcaacaa atcataggtt agaaaaactg gtttatttgt tcttggaagc
    46021 gtgacaatcg ttgcatcaat ctcaaatatt tttttcatac actcttttgt gatcacttct
    46081 tcaggtgtac cttctgtgat caacttaccg tttttcattg ctaataaata atctgaaaaa
    46141 cgtgaagcat gattaatgtc atgaatcgac atcaagatcg ttgtttgttt catttgattg
    46201 atttcagtca ataactgtag gatctctaat tggtgtgccg gatctaaaaa tgttgtcggt
    46261 tcatccaaga tcaagatatc tgtttcctga gcaagcgcca tagcgatcca gacacgctgg
    46321 gtttgtccac cagacagcgt tgcgatatcc cgcatacgaa atccagctag acctgtagca
    46381 tccaacgccc actcgattgc ttcatgatct tgcgtgtcca tgccactgaa cagtttttga
    46441 taagggtatc gtccgtaaga tactacttct tctactgtca tacctgtagg gtgttcacta
    46501 gtttgtgcta ataatgtaat tttttttgca agttcttttg aactgtatgt agagatatca
    46561 gagttattga caatgatctt tcctgatttc acaggtagta tacgggtaaa acttttcaat
    46621 aaagtagatt ttccacttcc atttggccca atcaaactag tgattttccc ttcaggaatc
    46681 gtaacagaca tgttttcaat gatttttttg ttttcgtagc cggctgcaat gtcagctgct
    46741 cttaatctcg tcatttcacc catcctttcg ctgaaaatca ttctcaatta tgacgctgtt
    46801 tcaacatttc gtcaagcgct actttcatat ctatagccaa atgaagcggt tgacagcgtt
    46861 cgaaatatca ggaataataa ccaatgagaa agattctcaa ttatgttagg aggaaagaaa
    46921 tgaaattaaa aacaaaagta ttcacattat ctagcatatt gctgctggct ggagtactga
    46981 gcgcttgctc cccctcttca gataaagaaa cagctacaac tgccaattcg acgacttcat
    47041 ccaatagtac tcatacagtc acagatacac ttggacataa agtagagatt ccaaacgcgc
    47101 ccaaacggat catcggcagt tacttagaag actatctgat tgcactaggg gaaaaaccta
    47161 tcgcccagtg gactgttggc agtggttcca ttcaagatta tctgcaagat gatttaaagg
    47221 atgtcccaac gatttcttat gaccttcctt atgagaaagt gttaagcttt gagcctgatt
    47281 tgctgttgat ttcttcttcc gctactgtcg aaggcgggaa atacgaacaa tatagcaaaa
    47341 tcgcgccaac ttatgttgta aaaaacggaa cagatgtcac atgggaagaa caactaaaag
    47401 atgtcggcaa agctttggca aaagaaaaag aggcagaaaa aatcatttcc gattatcaaa
    47461 aatccatcaa gaaaactcga gaagaactag cagataaaat cgagaacaag acagctgcag
    47521 tgttgtgggt gaccaacaac tcagccttta tggtcagcaa aaatcggtca agtggaagaa
    47581 tcgtatacga cgatctggaa tttggtgttc ctgatctagt ggaagaggtc tccaaaaaag
    47641 ccacttctga ctggtctgct gtttcctctg aaaagctagc tgaattagat gctgactaca
    47701 tcatccttgt gaacagtgac aaagatgctg ccatgttcaa tgaaccaagc tggaagaatc
    47761 ttaaagcagt gacagacaat catgtactgc aattcggacc tgaatctagt tggctatata
    47821 acggacctat tgccagtcag gaaatggtca atgatatcaa agaaaaacta aattgatttt
    47881 aactaaaaaa agaatcttca cgattagtcg tgagatgctt tttttcttat taacaaacta
    47941 gacgcataga ttttattctt cttttgaagc aaccctattt tttactcttt cccatttttg
    48001 aaaacgatgg gcatatagat tttcttgatc cgttatcccc tcatactcct ctataagggc
    48061 gaagtctgaa aaatcaatat tcccaatata cgtatcgcct tcaaacgtgc tatcgatcaa
    48121 tgttcgccag atccgaccag tgtaaggaag aagttcttga aaaatccgac taccacccga
    48181 aacatagata tcttctgaga tcgtttgact atacgacaaa agttcatcga tcgaatgcat
    48241 tacttccgca ttttctttcg tgcgaaaatt tggttgcgtt gtcaacacga tgatatggcg
    48301 ataaggaagt gaaagatccc ccattccttc ataggtcttt cttcccatca ctaaaattcg
    48361 atccattgta tgttcgcgaa agaaacgcat atcatttggc aatcgccatg gtaacaaacc
    48421 atttttgccg atcagaccat ttttatcttg tgcccacatg gaaataaaca tattatccgc
    48481 tccttatgat tttagatgtt ttgagataaa aaaagtctca attctttgac cagcaaggaa
    48541 ttgagaactt taaaaacatt attttgtttc acggtgcaaa gtaactttgc gttcgcgtgg
    48601 gcaatatttt tgtttttcca aacgatcagg attgttacgt ttgtttttgc ttgttagata
    48661 gttacgttct ttacaagaag tacactctaa agtgatgttt acgcgcatgt ttttccctcc
    48721 catttttaca agaatcctct aagatgactc tcagacttga ttatcttacc atgatttttt
    48781 ctagattgct agtgtttttc acgattttgt taagtaaaac tacttgacga taaatacaac
    48841 ggttttactt ctcaaacaaa atctttttct ttttgtataa atacccttac acttgtttat
    48901 atagattatg ttttttaata aagggggata ctaatatgcc atggaacatg aaggactttc
    48961 ctgcatcaat gaaaaactta gataaattga caagaaaaaa agcaatcgac atcgcaaatg
    49021 cattattaga tgaagggtac cctgataacc gtgcgatccc aattgccatt gatcaagcaa
    49081 aaaaatggta tgaagatgct agtgaatcag aaaaacgaac tttcgaaaaa gaaaaaaatc
    49141 caagcaagac ggatgaacac gatacgaatc ctcgtgctgg aaaactgctt gattcagatg
    49201 tgatcgtaga atatgaggaa gaacaatgga tcgtgaaatc taaaggggca aaaaaggcaa
    49261 gcaaccattt tgatacaaaa aaagaagcaa tcgaaaaagg aaagcaagta gcacaaaaca
    49321 aagaatcaac tttgttcatt tataaaaaag atgggacaaa agaaaaagaa atcgattatt
    49381 gaacatatgt aaaggggttg tgacgaaaat cgtgtcacaa cccccttatg ttcgaaacaa
    49441 tggtgttcct ctgccaactc cgaaccataa gtcataatat ctataaaacg ggaagagctg
    49501 ttttttgaaa ttgtttctta tcactcagtg ttaaacggta ggagaaaacc tcttttttat
    49561 tgatatttga ttttcatcaa acagtcacat agtcgattgc ttctgcttgc ggaatcgttt
    49621 catctacaaa gtagacttta taccatgtca agaaactgaa gattgtccag atttttcttt
    49681 gctcttcttt acgtccttcg tgatggtcat ctagcaactt catgattttt tcttgatcaa
    49741 aaaattcttt tgcaaaatct gcttcgaata atgctttgac ttgttcgtag ccgtgttctt
    49801 ctttcaacca agctttgatt ggcacaggga atcctaattt cacacgattc gaccattctt
    49861 ccggaagatg tttgttcgca gcttgtctga aaatatcttt tgtgttgttt tgattcaata
    49921 aaaacttact tggtatttgt tgagccaatt tcatgacttc gatatccaat aaaggtactc
    49981 ggacttccaa agaacttgcc atagaaagtt tatctgcctt taacaagata tcttttggca
    50041 tccattgatg aagatcgaca tattgcatct tattgacttc atctttgatt ccttctgttt
    50101 tctcgtaatg aacagtcatg atttcatcca cagatggtgc tgtttgatat tttggtgtta
    50161 acacttctga tgcttctgat tcttcgaaca ctcgagcatg accgataaaa tattcttttg
    50221 caggagcaag tgattcatat aaatggatcc gtccatggaa atttttcatt tttccgattt
    50281 tacgtcctaa attatagcgt gttccttttg gtaatttttt caatccttga gcaatcacac
    50341 ggatgaattt tgaattcgta tggaatccat acgtttggta tcccgcaaac agttcatccg
    50401 ccccttctcc agattggact acccgcacac tttgtgaagc aagatttgct aaaaagtaca
    50461 aaggtacgca agaaggattt gaatcaggtt catctaagtg atactggatc aaagggaatg
    50521 ctttgaacga catgtctccg tcgatcactg ctgctgtatt atctaagtcc aatagttcgg
    50581 ttagttttct ggcttcaatc gcttcattat aggttttatc atcaaacccg attgagaaag
    50641 aatgatctgg tttcaataca gaggttacat aactggaatc aaccccgctg gataagaaag
    50701 aaccaacttc tacatcactg accgtatgtg cttcaataga agcttgaacg gtttcgtcga
    50761 ttttttcgat ccattcttgt cgggaatgcg tttcttttgt ttcaaaatct gcatcccaat
    50821 attgctgaat gtctagtttt ccatctttat acgtataata atggccttca ggcaaacgat
    50881 agacatcttt gaagaatgtt tcgccgttta atggagaata ttggaaagtc atataaggtt
    50941 tcaacgcttc tttgttcaat tctttgttaa aatcaggatg aggcagaaaa cttttgattt
    51001 ctgaaccaaa cataaatgtt ccgttcattt ctgcataata atatggtttg atcccaaagt
    51061 ggtctcttgc accgaataac tcattctttt cattatccca aatagcaaaa gcaaacattc
    51121 cgcggatctt ttgcaataat tctgttcccc attcttcgta accatgcaaa aggacttctg
    51181 tatctgcatg tgtttgaaaa acgtggccag ctgcaatcaa ttcttctctc aaaggctggt
    51241 aattatagat ttcgccatta aaaataatga tctttgtccg atcttcattg taaataggct
    51301 gagtaccgcc ctctaagtca ataatactta atcttctgaa tcctaaagca acatgtttat
    51361 cgatatattc tcctgaacta ttaggtccac ggtgaacgat tcgatccatc attgtattaa
    51421 taattgtttt tttgttgtcc ttgtcgttaa caaaacctac aataccgcac atttaacttt
    51481 cacatcctaa tataaaatta ctgtttattt cattcatatg catcttatca tagaataaat
    51541 agcggacgaa tattttctct cttacaattt cgtcacgtga aaacaaaaga tgaaagtttc
    51601 tgtttttaca gaaaataaag tcccaatatc taatttacca tgttttcttt tttgaggcta
    51661 ccttattctc ttcgtgttaa aaaaatatta gtggatgcta tttccaaaaa aaacagcaaa
    51721 aaaagacacg acctaaagat cgtgtctaat tatgactgta tcagaaaata tgataccaaa
    51781 cggatctatt cattaattaa ttgacatagt ttatctgttg ctcttttatg actggataac
    51841 tgaccaattc atgacgatcc aagtcttctt tatttatatt tacagcagta atttgactgt
    51901 cttcatacgt acgataataa taaatccctt tatcaacgtt acagcaagaa gaataaatcg
    51961 tatattcgta ttttccttct ccagtatcgc atactccttt ttgttgctcg actgagccta
    52021 gtatatgaaa aaattgactg atactttcag attctgaatc acctgatgca gcattcattt
    52081 tagtaaatgt ggcttttaca aatcgagaaa cagaagagag atctccaggt aagcccaatc
    52141 ctcccatccc acgactataa acattcaagc tgatctggtt tgaaaaatga ttttctggtg
    52201 ttccatttga tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat
    52261 tatttgtcaa cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa
    52321 ttactatcga tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt
    52381 cactaaaatc gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg
    52441 ttgagcattg ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt
    52501 cttgtaattc tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt
    52561 tttcatttgt agcctcataa tagagtggat agttggatac cccagctgct attcctatca
    52621 ttgcataatg tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag
    52681 taatagtgac tacttcatta taagacatct cataatcaaa attccttcca aaataatggt
    52741 ctttcgttgc ataagtgatt gcggtacaca tcgttttccc tcctaaaaca aatcgttttt
    52801 acacttttat cttacatcta gtattttttt ttatcaaaaa aaaggccaaa gaagattgat
    52861 ttactagcat ttataaaaaa tagtactcag ggggaatcaa aaaatattgt aggttaaaag
    52921 tacaacaata aggggctgtg acaaaagtct tgtcacagcc ccttattccg aacaaacggt
    52981 gttcaaaagc ttgcatctgc ggtaataagc ccaaccaaac gaaaaaatag gaaaagctat
    53041 ttttgtttgg ccgttcttat tacttgatgc aggacagctt cttcacaacc tctaatcgtt
    53101 gatataagga aggtacagga tttgaacctg cgcgccggta ttagccggtt cgccggattt
    53161 cgagtccggt gcattaccac tctgccaacc ttccgtaagt actattttta aacttttttc
    53221 acgaaatgtc aagcctattt ctaatagata aataacagaa atcgcttttt ttagcaaaaa
    53281 agtccattga cagtttgcag ccaacggact taccgatcaa attcatactg atagaacact
    53341 atctgattat ttcaggatta tctaatgcta aaatcgagtc aattgtccgt ttgatcagtg
    53401 caatgatttg ttcttctgtt ggatgcatga tgtttgatga catcaatgac gctaagccag
    53461 tcactgctac ccatgtacca gtatgcagag catcgacata ttcatccgat aattgattgt
    53521 atctttcatc ttctttaact atttcacgga aataattgta tgaaaaatca tgcattttct
    53581 ttccgtcccc atgttcatca atgtacaatg ccatgtaaag actatgatgc ttttttgcaa
    53641 agtagatata gttcaaaccg agatcaatga ttttatcacc agtacgttca atagggaaaa
    53701 catcttcttt tagttgttca aagatagaat ccagcaacgt attttttaaa tcttccatgt
    53761 ttttgaattc cagataaatc ggctgtgtcg aaatccccat ctttttagca atatttctcg
    53821 cagtaaatcc tttaaaccct tcctttgcaa caacatcata agcagctttt agaatttgat
    53881 ccttggtata gacttttctt ctcattaaaa ctcccccact tctttactgc agtatatgtt
    53941 gttttattgt accctatttt tagcattttt tgcaaacatt ttactcaaaa cgttatattt
    54001 taaatttttt tcagtcttct ttaacttttt tttgcaaaat taaaaaaatt tggttaaatt
    54061 caatgggttc ccttacattt ttagttttga cctaaatgat agttgtccaa atctttcatt
    54121 tcaagttata gttaaagaaa atgaaaaaga aggtgtgtaa tggaaaacga aactgacgtt
    54181 atttatattc atcctcaaaa acgaatcgtt tcacagaaaa gaaagtattt ttatcttggt
    54241 tttacaggtg ttttttttct ttttattggc ttgctttcta atactcctac tgataattgg
    54301 agtggattgc taactattct tacctcgcca agcaatcttt tgacagatta ttttgcttta
    54361 ggtgttttcg gaagcgcatt cataaatgta gggattttga ccttactttc tgtgctttta
    54421 gcttatcggc acaaggtgat tttaaacggt cccttatttg cttcgattct aacagttacc
    54481 ggtttctctt tttttggcaa aaacctttat aattctatct caatcatttt aggtgtgtat
    54541 ctatacgctg tatttgtcaa taaacctttt tctcagtaca tcatgatcgg actgtttggt
    54601 agcgtattat caccggtcgt tagttatatc acttttggta tgcgttttcc tttactgata
    54661 ggtattttat tggggaattt agctggcata gcaattggta tacttcttcc gcccttagct
    54721 gctcaaactt tagttttcca tcgtggattc acactttata atattggatt cacctctggg
    54781 ttgattgcga tgacttttac tgctgttttg aggttattca gctattcaat cgtcgaaaat
    54841 acattggttt tcaatgaata tcactttcct ctcatttgga ttatttttgg ctttttttcg
    54901 ctgacagtcg gaattggttt ctattataat tcctttcggc tttcggggat tcgagaaatt
    54961 ttcgattcat ctggaaaatt gacaactgat ttcattgcta attctggtat tggtgctact
    55021 ttgatcaaca tgggcttagt tggtctgatg ctgtcttctt atgttttgct ggttggcggt
    55081 cagttaaatg gacctgtcat cggtgctatt ttatctgcgg tgggtttcag tgcttttggt
    55141 tgtcatttaa aaaacagttt tccgatacta gtcggaatat ttattgcttc tttgtttgga
    55201 acttttcatg agatcaccag tactggcatg cttgttgcag ctgtgtttgg gacaggtctt
    55261 gcgcccataa gcggttttta cggcagtttt tacggtgtaa tagctggtgt gctacatatt
    55321 gctcttgtcc ataacgtcag cactttgcac ggaggactaa atctatataa cagtggtttt
    55381 tcaactggtt tcgttgcagg tatccttgta ccgatactag ataactttac cgctgtcaga
    55441 aaggaaaaaa agacacttgg aaaaagaatt atcaaaaaga atcatcgatg agcttcttac
    55501 ttatttatat tcccatgaaa taactgaaat acgtattgga gtagaatttg ctgaggaagg
    55561 gcttttcata gagatacagg gtacggcaga aactcagcca gaagatttag atgtacttgc
    55621 tgatttgctg aacaatcctc gggaccctag tatggaaatc tactatcaag aactattagg
    55681 taatccccga catgatcggg aagattatca tctgttaggt agtttgattg atgacgtgga
    55741 aatcatgtat gcccagccga ttatcaatat taagatcttt cgacgtgctt ctcattccta
    55801 ttattaaccc tattttctat ttataaaaga ctgaatcaaa aaagcagctc ctgaaagttc
    55861 gattaaaatc tactttcagg agctgttcaa gcttgacatt attgattttc caatccttca
    55921 tacacttcat ctgttacagg ttctaaaaac tctgaattac cagcagtgat cgccaaatgt
    55981 tcaaaccaac tgtcttttgt cgcaccatgc caatgtttaa tccctttgtg cgttacgacg
    56041 acatctccag ccattaatcg tcttgctggc tttccttctt cctgatacca gccttctcct
    56101 ccggtcacaa gtaagatttg atagccgtct gtatggacat gccagtgatt gcgacaacct
    56161 ggttcaaaag ttacattacc tacaccaaca gaaacttcgg gatcattcac taacatattc
    56221 agatagcttt gcccggtaaa tacttgagcg taagcttcgt ttttttcacc tgctggaaaa
    56281 atcacgccat tgtgtatttc ttcgtgtttt gtcatcattt acgcctcttt cttatcttcg
    56341 ctattttctt ctaaatagat ttcttttgct aaactaaaag ctgaccaagc ttttggccat
    56401 tctacataaa aagctaaatg ggtaatgatt tctgctattt cttcactagt aatgccattt
    56461 tgcttgccaa tcttcagatg agctggcaat tgttcaaaat ttcctcctga aattaatgca
    56521 gatatggtga tgatactacg ctgatgagca gataattctt ctctggacca tacttgtcca
    56581 aataaaacat catcatttaa ttctgcaaat tttggtgcaa aatctcctaa ttgatctcgt
    56641 cctgcggttt gtttttctgc catttctctt attctccctt cacgactgtt aggtgattca
    56701 actatggttc taaggcaact ttattttcta ttgtttcttc gcatttcatt ttaaatgtag
    56761 tctttcagcc tgtccaatgc ttagtttatt cagtcgatat gctttttaag catagttgct
    56821 aacgcttttt ttattttaaa aaaaacaagt tattaaataa gtctttagtt ggatgttttt
    56881 ttgagatcaa tcttttatac ttatgatgaa cttacaaaat tgtttgtttt ctgtcatatc
    56941 aaaaaatggc gcagttagtt gcttttctag taaagtatag ttaacaaaga acctctaagg
    57001 agttgatgaa taatgaatat tgctgcctct cgaaaactga taaatttcat atccattatc
    57061 ggattaggcc tatcaatcgc gctgacgatt tattttatta atttaggtgt tttcaaagat
    57121 ttgaatgcgt taagaggatt agtaggtgat tccatcattt taggaccgat tatttttgtc
    57181 ttcatccaaa tcctgcaagt agttattcca atcattcctg gagggatcag tactgcagct
    57241 ggtgtcctga tatttggccc ttatgctgga tttatctata actatattgg aatctgcatt
    57301 ggttcgatta tcatttttct gctagggcgt cgttatggaa agccattcat actttccatg
    57361 attagcgata agacatataa caaatatatt ggctggctgg ataatcaaaa ccgttttgag
    57421 aagctgtttg ctctagctat ttttcttcca gttgctcctg acgatgcgtt atgtttgatg
    57481 gctggattga caaacatgtc agtgaaacga tatacactaa tcattttgat tgctaaacca
    57541 ctgtcgattt tcttatatag tatggccttg atttatggag gtcaatatct aagtggtctt
    57601 cttggataat atttattttg taaaattagt cattgattga caatgt
//
LOCUS       DAPBBV010000014        56429 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.014, whole genome shotgun sequence.
ACCESSION   DAPBBV010000014 DAPBBV010000000
VERSION     DAPBBV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.014"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            330..1175
                     /locus_tag="RD486_001065"
     CDS             330..1175
                     /locus_tag="RD486_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7662809.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="RD486_001066"
     CDS             1456..2676
                     /locus_tag="RD486_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HDT7662810.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="RD486_001067"
     CDS             2673..5393
                     /locus_tag="RD486_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7662811.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="RD486_001068"
     CDS             5377..6321
                     /locus_tag="RD486_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7662812.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="RD486_001069"
     CDS             complement(6390..7400)
                     /locus_tag="RD486_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7662813.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="RD486_001070"
     CDS             complement(7580..7924)
                     /locus_tag="RD486_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7662814.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="RD486_001071"
     CDS             complement(7917..8351)
                     /locus_tag="RD486_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HDT7662815.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="RD486_001072"
     CDS             8489..9226
                     /locus_tag="RD486_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662816.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="RD486_001073"
     CDS             9219..10430
                     /locus_tag="RD486_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662817.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="RD486_001074"
     CDS             10634..11416
                     /locus_tag="RD486_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HDT7662818.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="RD486_001075"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="RD486_001075"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDT7662819.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="RD486_001076"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="RD486_001076"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDT7662820.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="RD486_001077"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="RD486_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HDT7662821.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="RD486_001078"
     CDS             15018..16067
                     /locus_tag="RD486_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HDT7662822.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="RD486_001079"
     CDS             16064..16342
                     /locus_tag="RD486_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDT7662823.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="RD486_001080"
     CDS             16317..16787
                     /locus_tag="RD486_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDT7662824.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="RD486_001081"
     CDS             16804..17106
                     /locus_tag="RD486_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662825.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="RD486_001082"
     CDS             17123..17494
                     /locus_tag="RD486_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HDT7662826.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="RD486_001083"
     CDS             17466..17825
                     /locus_tag="RD486_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662827.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="RD486_001084"
     CDS             17997..19004
                     /locus_tag="RD486_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7662828.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="RD486_001085"
     CDS             19029..20213
                     /locus_tag="RD486_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDT7662829.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="RD486_001086"
     CDS             complement(20650..22233)
                     /locus_tag="RD486_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7662830.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="RD486_001087"
     CDS             complement(22811..22954)
                     /locus_tag="RD486_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HDT7662831.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="RD486_001088"
     CDS             complement(23177..23656)
                     /locus_tag="RD486_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7662832.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="RD486_001089"
     CDS             complement(23729..24013)
                     /locus_tag="RD486_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662833.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="RD486_001090"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="RD486_001090"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="RD486_001091"
     CDS             complement(24357..25643)
                     /locus_tag="RD486_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDT7662834.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="RD486_001092"
     CDS             25781..26452
                     /locus_tag="RD486_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDT7662835.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="RD486_001093"
     CDS             26418..26906
                     /locus_tag="RD486_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HDT7662836.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="RD486_001094"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="RD486_001094"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDT7662837.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="RD486_001095"
     CDS             27867..28631
                     /locus_tag="RD486_001095"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDT7662838.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="RD486_001096"
     CDS             28864..31077
                     /locus_tag="RD486_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDT7662839.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="RD486_001097"
     CDS             31088..31534
                     /locus_tag="RD486_001097"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDT7662840.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="RD486_001098"
     CDS             31705..32964
                     /locus_tag="RD486_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HDT7662841.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="RD486_001099"
     CDS             complement(33053..34000)
                     /locus_tag="RD486_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7662842.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="RD486_001100"
     CDS             34394..35686
                     /locus_tag="RD486_001100"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDT7662843.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="RD486_001101"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="RD486_001101"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDT7662844.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="RD486_001102"
     CDS             37579..38454
                     /locus_tag="RD486_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7662845.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="RD486_001103"
     CDS             38720..40603
                     /locus_tag="RD486_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDT7662846.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="RD486_001104"
     CDS             complement(40678..40962)
                     /locus_tag="RD486_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDT7662847.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="RD486_001105"
     CDS             complement(40952..41686)
                     /locus_tag="RD486_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDT7662848.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="RD486_001106"
     CDS             41815..42438
                     /locus_tag="RD486_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDT7662849.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="RD486_001107"
     CDS             42630..43751
                     /locus_tag="RD486_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDT7662850.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="RD486_001108"
     CDS             43758..46886
                     /locus_tag="RD486_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HDT7662851.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="RD486_001109"
     CDS             46905..50099
                     /locus_tag="RD486_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HDT7662852.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="RD486_001110"
     CDS             complement(50245..50952)
                     /locus_tag="RD486_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7662853.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="RD486_001111"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="RD486_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDT7662854.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="RD486_001112"
     CDS             52447..53100
                     /locus_tag="RD486_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HDT7662855.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="RD486_001113"
     CDS             53326..54324
                     /locus_tag="RD486_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HDT7662856.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="RD486_001114"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="RD486_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDT7662857.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18565 a         9736 c        11693 g        16435 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcat tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt atttttttaa ggctctatac
    56401 tttttgatgt tggtgaactt caccaacat
//
LOCUS       DAPBBV010000015        55950 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.015, whole genome shotgun sequence.
ACCESSION   DAPBBV010000015 DAPBBV010000000
VERSION     DAPBBV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.015"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(11..592)
                     /locus_tag="RD486_001115"
     CDS             complement(11..592)
                     /locus_tag="RD486_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7662858.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(725..1408)
                     /gene="rpiA"
                     /locus_tag="RD486_001116"
     CDS             complement(725..1408)
                     /gene="rpiA"
                     /locus_tag="RD486_001116"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HDT7662859.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            1727..2140
                     /gene="rpsL"
                     /locus_tag="RD486_001117"
     CDS             1727..2140
                     /gene="rpsL"
                     /locus_tag="RD486_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDT7662860.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            2224..2694
                     /gene="rpsG"
                     /locus_tag="RD486_001118"
     CDS             2224..2694
                     /gene="rpsG"
                     /locus_tag="RD486_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDT7662861.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            2788..4875
                     /gene="fusA"
                     /locus_tag="RD486_001119"
     CDS             2788..4875
                     /gene="fusA"
                     /locus_tag="RD486_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7662862.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            5047..6234
                     /gene="tuf"
                     /locus_tag="RD486_001120"
     CDS             5047..6234
                     /gene="tuf"
                     /locus_tag="RD486_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDT7662863.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            6641..6949
                     /gene="rpsJ"
                     /locus_tag="RD486_001121"
     CDS             6641..6949
                     /gene="rpsJ"
                     /locus_tag="RD486_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDT7662864.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            6980..7609
                     /gene="rplC"
                     /locus_tag="RD486_001122"
     CDS             6980..7609
                     /gene="rplC"
                     /locus_tag="RD486_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDT7662865.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            7637..8260
                     /gene="rplD"
                     /locus_tag="RD486_001123"
     CDS             7637..8260
                     /gene="rplD"
                     /locus_tag="RD486_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDT7662866.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            8260..8550
                     /gene="rplW"
                     /locus_tag="RD486_001124"
     CDS             8260..8550
                     /gene="rplW"
                     /locus_tag="RD486_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDT7662867.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            8589..9422
                     /gene="rplB"
                     /locus_tag="RD486_001125"
     CDS             8589..9422
                     /gene="rplB"
                     /locus_tag="RD486_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDT7662868.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            9465..9743
                     /gene="rpsS"
                     /locus_tag="RD486_001126"
     CDS             9465..9743
                     /gene="rpsS"
                     /locus_tag="RD486_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDT7662869.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            9766..10113
                     /gene="rplV"
                     /locus_tag="RD486_001127"
     CDS             9766..10113
                     /gene="rplV"
                     /locus_tag="RD486_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDT7662870.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            10127..10783
                     /gene="rpsC"
                     /locus_tag="RD486_001128"
     CDS             10127..10783
                     /gene="rpsC"
                     /locus_tag="RD486_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDT7662871.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            10786..11220
                     /gene="rplP"
                     /locus_tag="RD486_001129"
     CDS             10786..11220
                     /gene="rplP"
                     /locus_tag="RD486_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDT7662872.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            11210..11398
                     /gene="rpmC"
                     /locus_tag="RD486_001130"
     CDS             11210..11398
                     /gene="rpmC"
                     /locus_tag="RD486_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDT7662873.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            11423..11689
                     /gene="rpsQ"
                     /locus_tag="RD486_001131"
     CDS             11423..11689
                     /gene="rpsQ"
                     /locus_tag="RD486_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDT7662874.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            11747..12115
                     /gene="rplN"
                     /locus_tag="RD486_001132"
     CDS             11747..12115
                     /gene="rplN"
                     /locus_tag="RD486_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDT7662875.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            12152..12460
                     /gene="rplX"
                     /locus_tag="RD486_001133"
     CDS             12152..12460
                     /gene="rplX"
                     /locus_tag="RD486_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDT7662876.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            12488..13027
                     /gene="rplE"
                     /locus_tag="RD486_001134"
     CDS             12488..13027
                     /gene="rplE"
                     /locus_tag="RD486_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDT7662877.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            13046..13231
                     /locus_tag="RD486_001135"
     CDS             13046..13231
                     /locus_tag="RD486_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDT7662878.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            13267..13665
                     /gene="rpsH"
                     /locus_tag="RD486_001136"
     CDS             13267..13665
                     /gene="rpsH"
                     /locus_tag="RD486_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDT7662879.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            13697..14233
                     /gene="rplF"
                     /locus_tag="RD486_001137"
     CDS             13697..14233
                     /gene="rplF"
                     /locus_tag="RD486_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDT7662880.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            14394..14750
                     /gene="rplR"
                     /locus_tag="RD486_001138"
     CDS             14394..14750
                     /gene="rplR"
                     /locus_tag="RD486_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDT7662881.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            14771..15271
                     /gene="rpsE"
                     /locus_tag="RD486_001139"
     CDS             14771..15271
                     /gene="rpsE"
                     /locus_tag="RD486_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDT7662882.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            15286..15465
                     /gene="rpmD"
                     /locus_tag="RD486_001140"
     CDS             15286..15465
                     /gene="rpmD"
                     /locus_tag="RD486_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDT7662883.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            15509..15949
                     /gene="rplO"
                     /locus_tag="RD486_001141"
     CDS             15509..15949
                     /gene="rplO"
                     /locus_tag="RD486_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDT7662884.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            15949..17244
                     /gene="secY"
                     /locus_tag="RD486_001142"
     CDS             15949..17244
                     /gene="secY"
                     /locus_tag="RD486_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDT7662885.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            17306..17953
                     /locus_tag="RD486_001143"
     CDS             17306..17953
                     /locus_tag="RD486_001143"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDT7662886.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            18144..18362
                     /gene="infA"
                     /locus_tag="RD486_001144"
     CDS             18144..18362
                     /gene="infA"
                     /locus_tag="RD486_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDT7662887.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            18395..18511
                     /gene="rpmJ"
                     /locus_tag="RD486_001145"
     CDS             18395..18511
                     /gene="rpmJ"
                     /locus_tag="RD486_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDT7662888.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            18529..18894
                     /gene="rpsM"
                     /locus_tag="RD486_001146"
     CDS             18529..18894
                     /gene="rpsM"
                     /locus_tag="RD486_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDT7662889.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            18922..19311
                     /gene="rpsK"
                     /locus_tag="RD486_001147"
     CDS             18922..19311
                     /gene="rpsK"
                     /locus_tag="RD486_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDT7662890.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            19391..20329
                     /locus_tag="RD486_001148"
     CDS             19391..20329
                     /locus_tag="RD486_001148"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDT7662891.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            20357..20737
                     /gene="rplQ"
                     /locus_tag="RD486_001149"
     CDS             20357..20737
                     /gene="rplQ"
                     /locus_tag="RD486_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDT7662892.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            21009..21848
                     /locus_tag="RD486_001150"
     CDS             21009..21848
                     /locus_tag="RD486_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7662893.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            21824..22693
                     /locus_tag="RD486_001151"
     CDS             21824..22693
                     /locus_tag="RD486_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7662894.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            22683..23480
                     /locus_tag="RD486_001152"
     CDS             22683..23480
                     /locus_tag="RD486_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDT7662895.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            23683..24429
                     /gene="truA"
                     /locus_tag="RD486_001153"
     CDS             23683..24429
                     /gene="truA"
                     /locus_tag="RD486_001153"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDT7662896.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(24884..27553)
                     /locus_tag="RD486_001154"
     CDS             complement(24884..27553)
                     /locus_tag="RD486_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HDT7662897.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(27791..27979)
                     /locus_tag="RD486_001155"
     CDS             complement(27791..27979)
                     /locus_tag="RD486_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDT7662898.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            28249..28611
                     /locus_tag="RD486_001156"
     CDS             28249..28611
                     /locus_tag="RD486_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7662899.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            28663..30345
                     /locus_tag="RD486_001157"
     CDS             28663..30345
                     /locus_tag="RD486_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDT7662900.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            30462..32498
                     /gene="recG"
                     /locus_tag="RD486_001158"
     CDS             30462..32498
                     /gene="recG"
                     /locus_tag="RD486_001158"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDT7662901.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            32547..33548
                     /gene="plsX"
                     /locus_tag="RD486_001159"
     CDS             32547..33548
                     /gene="plsX"
                     /locus_tag="RD486_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDT7662902.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            33670..33912
                     /gene="acpP"
                     /locus_tag="RD486_001160"
     CDS             33670..33912
                     /gene="acpP"
                     /locus_tag="RD486_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDT7662903.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            34180..35184
                     /locus_tag="RD486_001161"
     CDS             34180..35184
                     /locus_tag="RD486_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662904.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            35185..36129
                     /locus_tag="RD486_001162"
     CDS             35185..36129
                     /locus_tag="RD486_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7662905.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            36129..37091
                     /locus_tag="RD486_001163"
     CDS             36129..37091
                     /locus_tag="RD486_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662906.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            37118..38032
                     /locus_tag="RD486_001164"
     CDS             37118..38032
                     /locus_tag="RD486_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7662907.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            38058..39839
                     /locus_tag="RD486_001165"
     CDS             38058..39839
                     /locus_tag="RD486_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7662908.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            40187..40873
                     /locus_tag="RD486_001166"
     CDS             40187..40873
                     /locus_tag="RD486_001166"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDT7662909.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            40893..44474
                     /gene="smc"
                     /locus_tag="RD486_001167"
     CDS             40893..44474
                     /gene="smc"
                     /locus_tag="RD486_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDT7662910.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            44483..45292
                     /locus_tag="RD486_001168"
     CDS             44483..45292
                     /locus_tag="RD486_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7662911.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            45303..46301
                     /gene="ftsY"
                     /locus_tag="RD486_001169"
     CDS             45303..46301
                     /gene="ftsY"
                     /locus_tag="RD486_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDT7662912.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            46488..48755
                     /gene="gshAB"
                     /locus_tag="RD486_001170"
     CDS             46488..48755
                     /gene="gshAB"
                     /locus_tag="RD486_001170"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HDT7662913.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(48844..49296)
                     /locus_tag="RD486_001171"
     CDS             complement(48844..49296)
                     /locus_tag="RD486_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HDT7662914.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            49446..50396
                     /locus_tag="RD486_001172"
     CDS             49446..50396
                     /locus_tag="RD486_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDT7662915.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            50389..51348
                     /locus_tag="RD486_001173"
     CDS             50389..51348
                     /locus_tag="RD486_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDT7662916.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            51345..52100
                     /locus_tag="RD486_001174"
     CDS             51345..52100
                     /locus_tag="RD486_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7662917.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            52123..53076
                     /locus_tag="RD486_001175"
     CDS             52123..53076
                     /locus_tag="RD486_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7662918.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(53720..54016)
                     /locus_tag="RD486_001176"
     CDS             complement(53720..54016)
                     /locus_tag="RD486_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HDT7662919.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            54371..54727
                     /locus_tag="RD486_001177"
     CDS             54371..54727
                     /locus_tag="RD486_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7662920.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            54737..55636
                     /locus_tag="RD486_001178"
     CDS             54737..55636
                     /locus_tag="RD486_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HDT7662921.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        18402 a        10110 c        12006 g        15432 t
ORIGIN      
        1 tttttaggta ttagatgcat aattgctcga tttctttttc aggtaaattg atatatttat
       61 aacatgttcc aactgaaaca ccgcattttg aagaaataaa ttggatcgtt tctttttttt
      121 cataatagag acgtcggatt tttttgatcg tttttgcatc gatttttggt cttccgccga
      181 tttttccttt tttacgagct tcatctaatc caactaatgt acgttctttg atcaatgcgc
      241 actccatgtt tgctaggttt tccattaatt ggaaatagat ttttcccatt tcgcgcgtat
      301 cgattccttc atcaagacta atcaagtgca gcccgcgatc tttgaataat tgcgtgagtt
      361 ctgttaattg ccgcgtagat ttgcctaatc gatgaagttg gcaaatgact agtgcatcgc
      421 cttgttgcat gtcagcgatc actgactcca aatgaacagc agtagaatca ttttgttcca
      481 cttcatatgt ctcatggaaa atttcttgac aaccaaagtc agataattga tcaacctgag
      541 ttgttaaatc aacgtcattt atggttgtgc gtgcataacc aataattttc atggtgattc
      601 ctttctagca gtgattttct aactggatat aacagtaaaa atgtagcata aagtacgtca
      661 aaaagatagt tttttcgcaa attttccgct gtcttttttt attggatgat caagcagttt
      721 ttctttattt acgacggatt gcgtcaagaa tctcaacgcc tttttctgag ccgacaacta
      781 ctttagaaac catgtttagg aaaagcccat gttctactac cccaacaagt tcatctaaat
      841 aggtagctaa gctttctggc tgttcgatga cttctagatg cagatcaatg atgtaatgac
      901 caccatctgt ggttaagact tctccgtttt cgtctgtacg caagacgggt tggaatcttt
      961 tttcttcaaa aatatgaagt agctgttggg agccataagg gatcacttca actgggagtg
     1021 ggaacttccc aagtttatcg actaatttag aagaatcaac gatccaaatc gtttcttttg
     1081 agtacgtagc gactattttc tcgaaaagca aagcagcgcc gccgcctttg atcccttgaa
     1141 aatcagcact gatttcatca gcaccgtcta ttgtcaaatc gactacgggg acttcatcaa
     1201 tactctttaa cggtattcct aatttttccg cttgttcttt tgtcgcattt gaagtagtaa
     1261 ctcctgtgat acgtaaacct tcttcacgca tacggcgacc aatctcttct accatataat
     1321 aggcggttga accggtcccg agacctacga tcatcccgtc ctttacgaat ttcgcggctt
     1381 caatgccagc taattgtttt aaattcatct ttgcgtccac ctttttttag tttgagcatc
     1441 gtgctttcct cactatttta gcgtgattta cggtaaaaag ataccattct tttttattcc
     1501 aataaagctt tttcaaaaaa aattgcatct cttgttgaca tgttttttca ttcgtgatat
     1561 tctaacaaag gtgctttatc tacaggtttc tgtgaagaaa cgtgctgact gtttatcaaa
     1621 gcatatttga taaggatgca gacattgcat ttatttttta tcacaaaaaa agaaccacct
     1681 ggatgtgtgg aactagacgc aaatcgtggg aaggaggaaa caaggaatgc ctacaattaa
     1741 ccaattagta cgtaaacctc gtaaatcaaa ggtggaaaaa tctaattcac ctgctttgaa
     1801 caaaggatat aacagcttta agaaaactca aactaacgta aactcacctc aaaaacgtgg
     1861 ggtagcaact cgtgtgggta caatgacacc taaaaaaccg aactcagctt tacgtaaata
     1921 tgcacgtgtt cgtttgtcaa acttaattga agttactgct tatatcccag ggattggtca
     1981 taacttacaa gaacacagtg ttgtattatt acgcggtggt cgtgtaaaag acttaccagg
     2041 ggtacgttac catatcgttc gcggtgcttt agatactgct ggtgttaacg accgtaaaca
     2101 aagccgttct aaatacggaa ctaaaaaacc taaagcttaa ttttaattat taaacaaatg
     2161 aaacttgctt ctactatata gaagtaatta ctatgaacaa tatttcggaa ggaggagtta
     2221 cggatgccac gtaaaggtcc tgttgcaaaa cgtgatgttt taccagatcc tatttataac
     2281 tcaaaattag taactcgctt gatcaaccgt gtaatggttg acggaaaacg cgggattgca
     2341 gctaacatta tctataatgc ctttgacttg atcaaagaat ctacaggtaa cgatccatta
     2401 gaagtgtttg aacaagcaat gaaaaacgtt caacctgttc ttgaagttaa agcacgtcgt
     2461 gttgggggtt caaactacca agtaccagtt gaagttcgcc ctgaacgccg cgttactcta
     2521 ggtcttcgtt gggtagtaaa ctacgctcgc ttgcgcggtg aacacacaat ggaagaacgc
     2581 ttagcaaaag aaatcatgga tgctgcaaac aacacaggtg cttctgttaa aaaacgtgaa
     2641 gacactcata aaatggctga tgccaaccgt gcgtttgctc actatcgctg gtaagattct
     2701 ctctgtttgg tcggctttta taagtcgacc tcagatagtg tccttatttt tagcaactag
     2761 atagtaaaga gaggagaaac aaggagaatg accagagaat tttctttaca aaacactcgt
     2821 aatatcggta tcatggccca catcgatgct ggtaaaacga ctgctactga acgtatcttg
     2881 tactatactg gtaaaatcca taaaattggt gaaactcatg aaggagcttc acaaatggac
     2941 tggatggaac aagaacaaga acgtggtatt acgatcactt ctgctgctac tacagcacaa
     3001 tggaagggtc accgaatcaa catcatcgac acaccaggac acgtagactt cacagttgaa
     3061 gttgaacgtt cattgcgtgt acttgatggt gctgtaactg ttcttgatgc acaatcaggt
     3121 gttgaacctc aaactgaaac agtttggcgt caagcaacaa cttatggtgt acctcgtatc
     3181 gtatttgcaa acaaaatgga caagatcggt gctgacttct tatattcagt atcaacttta
     3241 catgaccgtt tgcaagcaaa cgctcaccca atccaattac caattggtgc ggaagacgac
     3301 ttcacaggaa ttatcgacct tgtaacaatg aaggctgaaa tgtatacaaa cgatcttgga
     3361 acagagatcg aagaaacaga aattcctgaa gaataccgcg aattagctga agaatggcgc
     3421 gaaaaattgg ttgaagctgt agctgaaact gatgaagaac ttactttgaa atacttagaa
     3481 ggtgaagaaa tcactgaagc tgagttaaaa gaaggtatcc gccgcgcaac agttaacgta
     3541 gaattctacc cagtactatg tggttcagca tttaagaaca aaggggttca attactattg
     3601 gacgctgttc ttgattactt gccatcaccg ttagatatcc cagctatcaa agggattgac
     3661 cctaaaactg atgaagaagt agaacgtcct gcagacgaca gcgctccttt ctcagcttta
     3721 gcatttaaag ttatgactga cccattcgta ggtcgtttaa ctttcttccg tgtgtactct
     3781 ggtgttttac aatcaggttc atacgtacaa aacgcaacaa aaggcaaacg tgaacgtgtt
     3841 ggtcgtatcc tacagatgca tgccaactct cgttcagaaa tctctgaagt ttacgctgga
     3901 gatatcgctg ctgctgttgg tttgaaagac acaactactg gggacacact atgtgatgaa
     3961 aagagtctag ttattcttga atccatggaa ttcccagaac cagttatcca agtcgctatt
     4021 gaacctaaat caaaagctga ccaagataaa atgggtgtgg ctttacaaaa actatctgaa
     4081 gaagatccta ctttccgtgc tgaaacaaac gtggaaacag gcgaaacaat catcgctggt
     4141 atgggtgaac ttcacttaga tatcatcgtt gaccgtatgc gtcgtgaatt caaagttgaa
     4201 gctaacgtag gtgcgcctca agtatcttac cgtgaaactt tccgtgctgg cactcaagcc
     4261 gaaggtaagt ttgtacgtca gtctggtggt aaaggtcaat acggtcacgt atggattgaa
     4321 tttacaccaa atgaagaagg tgctggtttc gaatttgaaa atgcgatcgt cggtggggtt
     4381 gttcctcgtg aatacattcc agctgttgaa actggtttga aagatgctat ggaaaatggt
     4441 gtcttagctg gctatccatt agtagatatc aaagctaaac tttacgatgg ttcataccat
     4501 gatgtcgatt caaatgaaac tgccttccgt gttgctgctt ctatggcatt acgtgcagca
     4561 gctaagaaag ctaatccagt aatccttgaa ccaatcatgg ctgtagaagt tgttatccct
     4621 gaagattatt taggtgatgt tatgggtcac gtaactgctc gtcgtggacg tgttgaaggt
     4681 atggaagctc gcgctggcgg ccaacaagtt gttcgtgcga tggttccact tgctgaaatg
     4741 tttggttatg ctacaactct tcgttctgct actcaaggtc gtggtacatt tacaatgaca
     4801 tttgaccact acgaagatgt accaaaatca gtacaagaag aaatcattaa gaaaaacggc
     4861 ggaaaagctg aataatttct tgaaaccgga tagtcctgca aagagattat ccaaagagac
     4921 tatattttta atatagtttc gtgtaaaata attatcgatg atatgggcat gtggtgtacc
     4981 ttgtgtacat catataccta tcagacaaat aaaaaatata ttgtattttt aggaggacat
     5041 tttaaaatgg caaaagaaaa atttgaccgt tctaaaccac acgttaacat tggtactatc
     5101 ggacacgttg accatggtaa aactacatta acagctgcaa tcacaactgt actatctaag
     5161 aaaaacggcg gccaagctat ggcttacgat caaatcgatg gtgctccaga agaacgcgaa
     5221 cgcggaatca caatctcaac agctcacgtt gagtatgaaa cagatacacg ccactacgct
     5281 cacgttgact gcccaggaca cgcggattac gttaaaaaca tgatcactgg tgctgctcaa
     5341 atggacggag ctatcttggt agtttctgct gctgacggcc caatgcctca aactcgtgaa
     5401 cacatcctat tgtctcgtca agttggtgtt ccttacatcg ttgtattctt gaacaaagta
     5461 gacatggttg atgacgaaga attactagaa ttagttgaaa tggaagttcg tgacctatta
     5521 acagaatacg aattccctgg tgacgatgtt cctgtagttg ctggatcagc tttgaaagct
     5581 ctagaaggcg acgcttcata cgaagaaaaa attcttgaat taatggctgc agttgacgaa
     5641 tacatcccaa ctccagaacg tgacaacgac aaaccattca tgatgccagt tgaagacgtg
     5701 ttctcaatta ctggacgtgg tactgttgct acaggtcgtg ttgaacgtgg acaagttcgc
     5761 gttggtgacg aagttgaagt tgttggtatt gctgaagaaa cttcaaaaac aacagttact
     5821 ggtgttgaaa tgttccgtaa attgttagac tacgctgaag ctggagacaa cattggtgct
     5881 ttactacgtg gtgttgcacg tgaagacatc caacgtggac aagttttagc taaaccaggt
     5941 acaatcacac ctcatacaaa attctctgca gaagtatacg tgttgacaaa agaagaaggt
     6001 ggacgtcata ctccattctt cactaactac cgtccacaat tctacttccg tacaactgac
     6061 gtaacaggtg ttgttgaatt accagaagga actgaaatgg ttatgcctgg cgacaacgta
     6121 acaatggaag ttgaattaat ccacccaatc gctatcgaaa acggtactaa attctcaatc
     6181 cgtgaaggcg gacgtacagt tggtgccggt gtcgttacag aaatcaaagc ttaattcact
     6241 taagttttaa agtaaagcaa catttattcg gacgtaatcg ctcggaacga aggtcttagg
     6301 atctttgttc cgagcttttt tatttattgc aggatcagga aaaaagacag gagtattata
     6361 aatagaagaa acacgaaata aaagagtcag tattttctaa atgaaacttt atgaaaacaa
     6421 aatgtttttt acaagaaaaa gccttgcttt gtgagtttat atatattata atgacaaagg
     6481 tgcgtttact ttagtgaatt gcacagacgt aatcagaatg atttcgtcgg ctaagaaacg
     6541 agaggttgcg acacgcccgg acgctttgcc acgaacgagc gtgacggaaa ttttcgtgga
     6601 gctatgtcta cttttcaaaa taggcgaagg agggaacaag atggcaaaac aaaaaattcg
     6661 tatccgttta aaagcgtatg aacaccgtat tttagatcaa tcagcggata aaatcgtgga
     6721 aactgcaaaa agaactggag ctagcgtgtc tggtccaatt ccattaccaa ctgaacgcag
     6781 tctttacaca atcatccgtg cgactcataa atacaaagat tcacgcgaac aattcgaaat
     6841 gcgtacacac aaacgtctta tcgacattgt gaacccaaca ccaaaaactg ttgatgcttt
     6901 gatgaagcta gacttaccat ctggtgtaaa catcgaaatc aaattataaa actaaaacaa
     6961 aaataatgga ggtgtactca tgaccaaagg aatcttaggg aaaaaagtgg gaatgacaca
     7021 aatcttcact gaatctggtg aattaattcc agtaactgtt gtagaagcta ctccaaacgt
     7081 agtactacaa gtgaaaacaa tggaaacgga tggctacgaa gctattcaag ttggttacca
     7141 agatatgcgt gaagttttat caaacaaacc tgcgaaaggt catgttgcaa aagcaaacac
     7201 ggctcctaag cgcttcattc gtgaattcaa aaatgttgag ctaggagaat atgaagtagg
     7261 aaaagaaatt acagtagatg ttttccaagc aggagacatt attgatgtaa caggtactac
     7321 gaaaggtaaa ggattccaag gggttatcaa acgccacgga caaagccgcg gaccaatggc
     7381 tcacggttct cgttaccatc gtcgtcctgg gtcaatgggt ccagttgcac ctaaccgtgt
     7441 atttaaaaac aaacgtcttg ctggccgtat gggtggcaac cgcgtaacta tccaaaactt
     7501 ggaagttgta cgtgtcgatg cagaaagaaa tgttatcttg atcaaaggta atgttcctgg
     7561 agctaaaaaa tctttaatta ctatcaaatc agctgtgaaa gctaaataat tgtaggaaga
     7621 aaggaggaac taaggaatgc cgaatgtagc attattcaaa caagatggaa gccaaaacgg
     7681 tgaaatcaca cttaacgaag aaatcttcgg aattgaacct aatgaaagtg ttgtttacga
     7741 tgcaatcgta atgcaacgtg cgtcattaag acaaggaaca cacgcggtta aaaaccgtag
     7801 cgctgttcgc ggcggcggac gtaaaccatg gcgtcaaaaa ggaacaggtc gtgcacgtca
     7861 aggatctatc cgctcaccac aatggcgtgg aggtggcgta gtctttggac caacaccacg
     7921 ttcttacagc tacaaacttc ctaaaaaagt tcgtcgttta gcaatgaaat ctgtattgtc
     7981 agaaaaagtt gctgaaaaca acttggtagc aatcgaaggc ttgaacttcg acgcaccaaa
     8041 aacaaaagaa ttcaaacaag ttcttgctaa cttatctatc gactctaaag tattggttgt
     8101 tctagaaaaa ggtaacgact ttgctgcttt atcagcacgt aacttaccaa acgtttctgt
     8161 agtaacttct gataatgtga gtgtgctaga cgttgtatca aatacaaaag tgttagcaac
     8221 acaaactgct cttactcaaa ttgaggaggt gcttgcataa tgaacttact agacgtaatc
     8281 aaacgcccag tgatcactga aaaatcaatg cttgccatgg atgacaagaa atacactttt
     8341 gaagtggaca ctcgcgcaaa caaaacttta gtaaaacaag cggtagaagc tgcttttgac
     8401 gttaaagtca aaaacgtgaa catcgtgaac gtacgtgcga aattcaaacg tatgggcaaa
     8461 tatgcaggat atacaaaaaa acgtcgcaaa gcgatcgtta cattgactga agattcaaaa
     8521 gaaatccaat tattcgaagc tgctgaataa gcactaatag ataactcatt aaattaggag
     8581 ggaaaaacgt ggcgattaaa aagtacaaac ctacctcaaa tggtcgtcgt aacatgacag
     8641 gttctgattt tgctgaaatc acaacatcaa cacctgaaaa atcattgtta caaccattga
     8701 aaaaccatgc tggacgtaac aacaacggcc gcatcactgt acgtcatcaa ggtggcggac
     8761 acaaacgcca atatcgcgtg atcgacttca aacgtaacaa agataacgtt gttgcaactg
     8821 ttcaaacgat cgaatatgat ccaaaccgtt cagctaacat cgcgttagta cactatgaag
     8881 atggagtgaa agcttacatc ttagcaccta aaggactaga agtgggtatg aaacttgttt
     8941 caggtccaga agcagatatc aaagtcggaa atgctcttcc attagaaaac attccagttg
     9001 gtactgttat ccacaacatt gaaatgaaac ctggtaaagg tggacaattg atccgttctg
     9061 ctggtacaag tgctcaagta cttggtaaag aaggcaaata cgtattgatc cgcttgaact
     9121 ctggtgaagt tcgtatgatc ttagctgcat gccgtgctac aatcggttct gtaggtaacg
     9181 aacaacacga attaatcaac atcggtaaag ctggacgctc tcgttggatg cgtaaacgcc
     9241 caactgtacg tggtagcgta atgaacccta atgatcaccc acacggtggt ggtgaaggta
     9301 aagctcctat cggacgtaaa gcaccagttt ctccttgggg tcaaccagct cttggttaca
     9361 aaactcgtaa caaaaaagct aaatcagaca aacttattgt tcgtcgtcgc aaaaataaat
     9421 aattactttg accatgtgtc gcacattttg agaggaggtt caccatgggt cgtagtttaa
     9481 agaaaggacc ttttgtcgat gagcatttaa tgaaaaaagt tgaagctcaa gcaggggttg
     9541 aaaagaaaaa agttatcaaa acttggtcac gccgttcaac agttttccca agttttgttg
     9601 gatataccat cgcagtttat gatggacgta aacatgtacc agtttacatc caagaagaca
     9661 tggtaggaca caaattaggt gaatttgcac ctacaagaac ttatcgtgga catgctgctg
     9721 acgataagaa aacgaaacgc taatttgagg ggaggataaa tccaaatggc agaacaaatc
     9781 acatcagcta aagcaactgc aaaaacagtt cgcacttcac ctcgaaaagc ccgtttagta
     9841 attgacctta tcagaggtaa aagtgtcgca gatgcaattt caatcttgaa attcacacca
     9901 aacaaatctg ctggaatcat tgaaaaagta ttgatgtcag cagttgcgaa tgcagaaaat
     9961 aactttgact tagatgttga aaacttggta gtaagcgaag cttttgttaa cgaaggacct
    10021 acaatgaaac gtttccgtcc tcgtgcaaaa ggatcagctt ctccaatcaa caaacgtaca
    10081 agtcatatca cggtagtcgt atcagaaaaa taaggaggga taatcagtgg gtcaaaaagt
    10141 acatccaatt ggaatgcgtg taggcatcat ccgcgactgg gatgctaaat ggtatgctga
    10201 aaaagagtat gctgagttct tacacgaaga tttaagaatc cgtaaattta tttcaactaa
    10261 acttgctgat gctgctgtat caacagttga aatcgaacgc gcaacaggtc gcgtaaacat
    10321 ttcaattcac acagctaaac caggtatggt tattggtaaa ggcggttctg aagtcgaaag
    10381 cctaagaaaa gaattaaaca aattaactgg taaaagaatc catatcaata tcgtggaaat
    10441 caaaaaacca gatctagatg caaaattagt aggtgaagga atcgcacgtc aattagaaaa
    10501 ccgtgttgct ttccgtcgcg ctcaaaaaca agccatccaa cgctcaatgc gtgctggcgc
    10561 tcaagggatc aaaactcaag tatctggtcg tctaaacgga gcagatatcg ctcgttcaga
    10621 aggatactca gaaggaactg ttcctcttca tactttacgt gcggacattg attacgcatg
    10681 ggaagaagca gatacaacat acggaaaact aggagttaaa gtgtggatct atcgtggaga
    10741 aattcttcca actaaaaaaa acactgagaa aggagggaaa taatcatgtt agtacctaaa
    10801 cgtgtaaaac accgtcgtga attccgcgga aaaatgcgcg gggaagctaa aggcggaaaa
    10861 gaagtagcat tcggtgaata cggtttgcaa gctgttgatt cacattggat cacaaaccgc
    10921 caaatcgaag ctgctcgtat cgcaatgact cgttacatga aacgtggtgg gaaagtatgg
    10981 attaaaattt tccctcacaa atcttatact gccaaagcaa ttggggtacg tatgggttct
    11041 ggtaaagggg cacctgaagg atgggttgca ccagtaaaac gtggtaaaat catgtttgaa
    11101 atcgcaggcg ttcctgaaga agtagctcgt gaagcgttac gtctagcttc tcacaaatta
    11161 ccaatgaaaa ctaagatcgt aaaacgtgag gaaatgggtg gtgaatcgaa tgaaggttaa
    11221 agaaatcaga gaattaacca ctgccgaaat gcttgatcaa gaaaaacaat taaaagaaga
    11281 attgtttaat cttagattcc aattagcaac aggtcaatta gaaaacactg cacgtattaa
    11341 agaagtacgt aaatcgattg cacgcatcaa aactgtgttg cgtgaacaag ctaagtaatt
    11401 atggaaggag gccattaagc gtatgactga aggaagaaat caacgcaaag tttatcaagg
    11461 tcgcgtggtt tcagacaaaa tggataaaac aattaccgtt gctgtcgaaa caaagaaaaa
    11521 ccaccctatc tatggcaaac gcatgaacta ttctaagaaa tacaaagtgc atgatgaaaa
    11581 caacacagca aaagttggcg acatcgtgag aattatggaa actcgtccat tatcagctac
    11641 aaaacgtttc cgtttgttgg aagtagtcga agaagcagtt attatctaat aacacgagat
    11701 tttcctatat agattgaatg caaaatctga aaggaggata cacaacgtga tccaagcaga
    11761 aagtcgttta aaagtcgctg ataactcagg cgcacgtgaa attttgacga tcaaagtcct
    11821 tggtggatct ggtcgtaaaa ctgctaacat cggtgatgtg atcgttgcta cggttaaaca
    11881 agcaacgcca ggtggggttg tcaaaaaagg tgacgtcgtt aaagccgtta tcgttcgaac
    11941 aaaatcagga gctcgtcgta cagacggttc atatattaaa tttgatgaaa atgctgcagt
    12001 gattattcgt gatgataaaa gccctcgtgg aacacgtatc tttgggccag ttgcacgtga
    12061 actacgtgaa aacaacttca tgaagatcgt ttcactagca ccagaagttt tataatcttg
    12121 agacacttat caaaggaggt gcgaaacagt tatgtttgtt aaaaaaggcg ataaagttaa
    12181 agttatcact ggaaaagaca aaaacaaaga aggcgttgta ctagcagcgt tcccgaaaaa
    12241 agataaagtt attgtcgaag gtgtaaatgt cgttaaaaaa caccaaaaac cttctcaagc
    12301 tgctcctcaa ggtggaattg ttgagatgga agcgccaatt catgtttcta acgtgatggt
    12361 ggttgactct actggtgtag ctggccgagt tggctacaaa gaagtagacg gcaaaaaagt
    12421 ccgtgtttct aaaaaaaccg gtgaagtttt agataaataa aagtttaagg aaggagggtc
    12481 ttactgaatg aaccgcctaa aagaaaaata tcttaaagaa gtaactccat cattgatgga
    12541 aaaatttaac tatagctctg ttatgcaaac acctaaagtt gaaaaaatcg tcatcaacat
    12601 gggtgttggt gatgcggtat caaacgctaa aaacttagat aaagcagttg aagaattaac
    12661 tttgatcact ggtcaaaaac caatgattac aaaagctaaa aaatcaatcg ctggattccg
    12721 tttacgtgaa ggaatgccaa ttggtgcaaa agttacattg cgcggagaaa gaatgtacga
    12781 attcttagac aaattggttt ctgtttcact accacgtgta cgtgacttcc atggtgtaag
    12841 taaaaaagcc tttgacggtc gtggaaacta tactttaggt attaaagaac aattgatctt
    12901 cccagaagta gattatgatt tagtagataa agtacgtggt atggacatcg ttattgtaac
    12961 aacagcaaac tctgatgaag aatctcgtga gttgttgaca caattaggca tgccattcca
    13021 aaaataatta aaggaggcga actacgtggc taaaaaatca atgattgcta aaaacaaacg
    13081 tcctgcaaaa ttttcaacac aagcttatac tcgttgcgaa cgttgcggac gtccacattc
    13141 agtttatcgt aagttccatc tttgccgtat ttgcttccgc gaacttgcct ataaaggtca
    13201 aattcccggc gtgaagaaag ctagctggta aaaagtaaat tcgcataaga aggaggtaaa
    13261 agatcaatgg tcatgacaga tccaattgca gattttctaa ctcgtatccg taacgcaaac
    13321 atggttaaac atgagtcttt agaagtacct gcatcaaaaa ttaaacgtga catcgctgaa
    13381 atcttgaaac gtgaaggttt cgttcgtgat gttgaataca tcgaagatga caaacaaggc
    13441 gtgatccgtg ttttcctaaa atttggtaaa aacggcgaac gtgttatcac aaacttaaaa
    13501 cgtatctcta aaccaggttt gcgtgcttat gtcaaagctg acgaagtacc aaaagtattg
    13561 aacggtttag gtatcgcaat catttcgact tctgaaggtg ttgtcactga taaagaagct
    13621 cgtgaaaaaa atatcggcgg cgaagttatc gcttacgtat ggtaatcaag tagaatctac
    13681 aaggaggtgt ctttaagtga gccgtatcgg aaataaagtc gttgttatcc ctgaaggagt
    13741 aacagttact caagacggaa acaacgttac agttaaagga ccaaaaggtg aattgactcg
    13801 tactttttca gcagatatca aaatgaatat cgaaggaaac gaagtaactt tcactcgtcc
    13861 aaacgacagt aaagaaatga aaacaattca tggaacaact cgtgcgaact tcaacaacat
    13921 ggttgtaggt gtcagcgaag gtttccaaaa agcgttagaa ctaatcgggg ttgggtaccg
    13981 tgcacaatta caaggatcaa aacttgtatt gaacgttggt tactcacatc cagtagaaat
    14041 cacaccacca gctggagtaa ctgttgaagt accagctaac acacaagtaa ttgttaaagg
    14101 tgcgaacaaa gaagaagttg gcgaattagc tgcaaacatt cgtggaactc gtcctccaga
    14161 accttataaa ggtaaaggta ttcgttatgt tggcgaatat gtacgccgta aagaaggtaa
    14221 aactggtaaa taatcgttta gaaaaattgc atagaagcca gcagcaggaa aaaggcattt
    14281 ggctgaagtt taccttcaaa aaaatacatt tttacttgtg ccgcagcttc tatttttcga
    14341 aacgtattta ctgcttgaaa tagtagtaca ataaaaataa agaggtgaca attgtgatta
    14401 caaaaccaga taagaacaaa acacgtcaaa agagacatcg tcgtgtacgt aacaatatct
    14461 ctggtactgc tgagcgccca cgcttgaacg tttttcgttc taacaaaaac atctacgctc
    14521 aaattattga tgacgtagcg ggtgtaacgc tagcaagtgc ctctaccttg gataaagaaa
    14581 tttcaggtgg aacaaaaaca gaagcagcac aagctgtcgg taaactagtt gctgaacgtg
    14641 cagctgaaaa aggcattaaa gtagtagtct ttgaccgtgg tggatacctt taccatggcc
    14701 gtgtgcaagc tttagctgaa gctgctcgcg aaaatggact agaattttag aagaaggagg
    14761 aataccattc atggtttata tcgatccaaa acatttggaa ttagaagacc gcgttgttgc
    14821 aattaaccgt gtaacaaaag ttgttaaagg tggacgtcgt ctacgttttg ctgctttagt
    14881 tgttgtcggt gacaaaaacg gacacgtagg atttggtaca ggtaaagctc aagaagttcc
    14941 tgaagcaatc cgtaaagcaa ttgaagatgc gaagaaaaac ttagttgaag tacctatggt
    15001 tggttcaaca atcccacacg aagtaatcgg tgcttttagt ggtggtagaa tcctaatgaa
    15061 acctgctgta gaaggttctg gggttgctgc tggtggacca gttcgtgccg tattagaatt
    15121 agctggggta gcagatatca cttctaaatc tttaggctca aatacaccaa tcaacgttgt
    15181 tcgcgcaaca gttgaaggtt tgaaacaatt gaaacgtgca gaagaagttg cagaacttcg
    15241 cggcaaatca gttgaagaat taatcggata aggaggacaa caataatggc tgaattaaaa
    15301 gttactttaa aacgcagtat tatcggacgt cctcaaaacc aacgcgatac agttaaagcg
    15361 ttaggtctta caaagattaa cagttcagtg gttaagcctt ctaatgaagc aattaaaggc
    15421 atgatcaata ctgtttctca cctagtggac gttgaagaaa tttaatttag aaaaatcata
    15481 actagaacat taaggaggtg ccaaacctat gaaacttcat gaattaaaac ctgctgaagg
    15541 ttcacgccaa gtacgtaacc gtgttggtcg tggtacttca tctggtaacg gaaaaactgc
    15601 cggacgcgga caaaaaggac aaaaagctcg ttcaggcggc ggtgtgcgtt taggatttga
    15661 agggggacaa acaccattgt tccgtcgttt accaaaacga ggattcacaa acgtgaaccg
    15721 taaagactat gcagtcatta atcttgatgt attgaaccgc tttgaagacg gagctgaagt
    15781 aactcctgtt gctttagttg aagctggaat cgtgaaaaac gaaaaagctg gaatcaaagt
    15841 attagctaat ggggaactaa acaagaaatt aactgtgaaa gcagcaaaat tctctaaagc
    15901 agctcaagaa gcaattgaag cggctggtgg atcaatcgag gtgatctaat gtttagacta
    15961 ttaaaagatg cttttaaagt aaaagacatt agatcgaaaa tcctatttac tgtatttgtg
    16021 ttgtttgtat ttcgcctagg tgcacatatt actgtaccag gcgtaaatgc tgcttcattg
    16081 caaaaccttt cttctttgcc atttttcaac atgttgaact tggtaagtgg tagtgcgatg
    16141 caaaactttt ccattttctc aatgggggtt tcaccataca ttactgcttc tatcgtcatt
    16201 cagcttcttc aaatggacat cgtgcctcga tttgttgaat ggtcgaaaca aggggaagtt
    16261 ggtcgtaaaa aactgaatca agcgactcga tatctgacat tagtattggc atttatccaa
    16321 tctgtcggta tcactgctgg attcaatcaa tacgctcaat taggtttcgt gaataatcct
    16381 aacgtagcaa cttacgtaac gatcggtttg attctaacag ccggtacgat gtttgttact
    16441 tggctaggag aacagatcac agaaaaaggt atcggaaatg gcgtatcaat gatcattttt
    16501 gcaggtatca tttctagatt gcctgaaagt atcagagaaa tttatgaaga ttactttata
    16561 aatattgatc cttcagacat atggaaatct gctatttttg tggccatttt actagtagcg
    16621 gtcttgttga tcgtgacatt cgtaacattt ttccaacaag ctgaacgcaa gatcccgatc
    16681 caatatacga aacgcgtagc tggcgcgcct acaagcagct atctgccgtt gaaagtaaat
    16741 gcagctggag ttattccagt tatctttgct agttcgttta ttgctacgcc aaatgctgtt
    16801 ttacaagcat tgagcggtag attcggttct gaaaactggt acaaagtgat gatggagatc
    16861 tttaactata atacagcacc tggtgctacg atttatacga ttctgatcgt tgccttcact
    16921 ttcttctacg cctttgttca agtaaaccct gagaaattag cggaaaactt gcaaaagcaa
    16981 ggaagttata taccaagcgt acgccctggt aaggggactg aagagtatgt ctcaagatta
    17041 ctgatgcgtt taagtacagt tggtgcagtc ttccttggtt tagtggcatt gcttccaatc
    17101 attgctcaaa tggtttggga tcttccacaa tcaatcggat taggcggtac aagcttactg
    17161 atcgttatcg gtgtagcttt agaaactgcg aaacagttag aaggcttaat gctgaaacgt
    17221 aaatatgttg gattcattga gtaagaaagc gtgttgaggt ttcccctcaa cacacgttct
    17281 cacacattta ttaggaggga aaacaatgaa cctcatttta atggggctgc caggcgcagg
    17341 taaaggaaca caagctgaaa aaatcattga tgcttatggt attccgcaca tctcaacagg
    17401 agatatgttc cgcgcagcga tgcaaaacga aacagctctt ggcctggaag caaagtctta
    17461 tatggataaa ggtgcattag ttcctgatga agtaacaaat ggaatcgtga aagagcgact
    17521 agctgaacca gatacagaga aaggcttctt attagatggc tttccacgta cgctagatca
    17581 agcaaaagct ctggacgcaa tgctaaaaga tttgaataaa aaaattgatg ctgtcatcga
    17641 tatccatgtt ggtgaagaaa tcttggtcga acgtctagcc ggccgattta tctgcagcaa
    17701 ttgtggagca acttaccata aaattttcaa ccctacaaaa gttgaagaca catgtgatcg
    17761 ttgcggtggg catgaattct atcaaagaga agatgataaa cctgagacgg ttaaaaatcg
    17821 tctggctatc aacatcaaaa atagtgaacc aatcttggct tattataaag aacaaggttt
    17881 gctaaacact attgatggtg ctcgtgaaat cgatgctgta tttgcagatg tacaaaaaat
    17941 cattgaaaaa tagcacgatt gcccgtagcc gacttgcatt atgcagttac tcttgtcaag
    18001 ttcaataaat tatgatagaa tatgtcagtc cgacttctag agaatcctct agatgatcca
    18061 ttttgagaat tttgaggtgg gaactgcagt ttccgccatt ttatcgtgtg aaaatgcgaa
    18121 acaagtacaa ggaggtactg tgcgtggcaa aagaagatat gattgaagtc gaaggtacag
    18181 tcgtcgaaac tttgccgaat gcaatgttta aagttgaact agaaaacgga caccaagttc
    18241 ttgctactgt ttcaggtaaa attcgtatgc attacatccg tatcttacct ggtgacaaag
    18301 taacggttga attgtctcca tacgatctta accgtggccg tattacttat cgctttaaat
    18361 aattgtactc cgtaaaacta caggaggtat tatcatgaaa gtaagaccat cagtaaaacc
    18421 aatgtgcgaa cattgtaaag taattcgtcg taaaggacgc gttatggtga tttgcccagc
    18481 aaatccaaaa cataaacaac gtcaaggata attggaggtg ctataaatat ggctcgtatt
    18541 gcaggagtag atattcctcg tgataaacgt gtagtagttt cacttactta tatctatggt
    18601 attggtaaca ctactgctaa aaagatctta gctgatgctg gtgtatctga agatgttcgc
    18661 gttcgtgaat taacgaatga acaaacagat gctatccgtg cagaagtaga taaattaaaa
    18721 gttgaagggg atcttcgtcg tgaagtgaac ttgaacatca aacgtttgat ggaaatcggt
    18781 tcttaccgtg gaatccgtca tcgccgtgga ttgcctgttc gtggacaaaa cacgaaaaac
    18841 aatgcacgta ctcgtaaagg cccagctcgc gctatcgctg gcaagaaaaa ataattctta
    18901 agtgaaggag gttaaaactt catggcagca aaaaaagtga atcgtaaacg ccgtgtgaag
    18961 aagaatatag aagcaggtat tgcacatatc cattctacat tcaataacac tatcatcatg
    19021 atcactgata ctcacggaaa tgcattagcg tggtcatcag ctggttcatt aggtttcaaa
    19081 ggaagcaaaa aatcaactcc ttttgccgct caaatggcag cagaaactgc tacaaaagca
    19141 gcaatggaac acggattaaa gactgttgaa gtaacagtta aaggacctgg ttctggacgt
    19201 gaagcagcaa ttcgttcatt acaagctaca ggtttagaag tgactgcaat tcgtgacgtg
    19261 actccagttc ctcataatgg tgcccgccct ccaaaacgcc gtcgtgttta atgagtgccg
    19321 ctcattttga gttttatcag taacgtcatt gaacaagaca cttttcgttt tgaaaggggt
    19381 aaagataaga atgattgagt tcgaaaaacc aagaatcgca aaaattgatg aagaaaaaga
    19441 ttatggcaag ttcatcgttg aacctcttga aagagggtat gggactactt tagggaattc
    19501 cctacgtcgt attttattat cttctttgcc aggtgctgcc atcactaata ttcaaatcga
    19561 tggtgtactg catgaattct ctaccatcaa aggtgttaga gaagacgtca ctcaaatcat
    19621 cttgaacatt aaaggcttag cgctgaaaat gtatggccaa gaagaaaaaa cccttgaaat
    19681 cgatattacc ggacctgcta cagtaactgc tggcgatatt atcgttgata gtgatgtaga
    19741 aattcttaac aaagatatgt acatctgtag tgtctctgaa ggagctacgt tccatgctcg
    19801 cttaacagtg aaacctggac gtggttatgt tcaagcagat gaaaataaaa aagaagatat
    19861 gccaattggc gttcttccag tcgattcaat ctacacacct gttcgtcgtg tgaactatca
    19921 agttgagaac acacgtgttg gacaccgtga agattttgat aaattgacga tggagatttg
    19981 gacagatggt tcaattgaac cgttggaagc aatgagtttg tctgcgaaaa tcatgactga
    20041 acatttggat atttttgtga acttaactga tgaagcaaaa aatgctgaaa tcatggtcga
    20101 aaaagaagaa acacaaaaag aaaaaatgtt ggaaatgacg atcgaagagt tagacttgtc
    20161 tgttcgctct tacaattgtt tgaaacgtgc aggaatcaat actgtacaag aacttacaaa
    20221 taaatctgag cctgaaatga tcaaagtccg taacttagga cgtaaatcat tagaagaagt
    20281 taaagcaaaa ttgcacgact taggtttagg tttacgtaaa gaagattaaa accttttacg
    20341 aaggagggaa accaacgtga gttatcgtaa actaggacgc acatctagcc aacgtaaagc
    20401 gatgttgcgt gatttaacaa ctgatttatt aatcaacgaa cgtattgtga ctactgaagc
    20461 tcgtgcgaaa gaagttcgct caactgcaga aaaaatgatc actttaggta aacgcggaga
    20521 tttgcatgca cgtcgtcaag ctgcggcttt cgtacgtaat gaagttgcca gcgtgcgtga
    20581 agaaaatgag gacatcgtca ttgaatcagc tttacaaaaa ctgttcaacg atattgcacc
    20641 tcgttacgca gaacgtcaag gcggatacac acgcattttg aagacagaac caagacgcgg
    20701 tgatggtgca ccaatggttg tcttagaact tgtctaaaat cacactaata acatcacttt
    20761 atagatgatt cttttagagt gttatgatgt tggaagatat ttttccgagt ctagctcagc
    20821 gctgctcctc aagcgaatat cgcttgggga gtaagcactc atcataaagt gtttttttat
    20881 accttcaatt acctgtcatg acagatatgt ttgaaggcat aaaaaaacat tttaagcgag
    20941 aaataattga aaattttgtc tttttttgat agtgttagta ggaactttag gatgaagaag
    21001 gagtaatcat ggagccaatt attgaattag aaaagataaa ttataaatac cagccagatg
    21061 atcttcgccc cgcattgaaa gatgtctcct ttacaattga taaaggtgag tggatcgcta
    21121 ttattggaca caatggttca ggaaaatcga cacttgccaa aacgatcaat ggattgcttc
    21181 tgccagaatc agggatcgtg aaagtgggaa atcaaatatt ggatgaagaa aatatttgga
    21241 cgatccgaca gatggttgga atggtttttc aaaatccaga caatcagttt gttggttcga
    21301 cagtagaaga tgacgttgct tttggtcttg aaaatcaagg gattcccaga gaagaaatgc
    21361 tagtgcgtgt gaaagatgca cttgagaaag ttagaatggc tgagtttgct tcacgcgagc
    21421 ctgctcgttt atcaggaggg caaaaacaac gtgttgccat tgccggcgtg gttgccttac
    21481 gacctgatat cattatttta gatgaagcaa ccagtatgct agatccagaa ggtcgtgaag
    21541 aagtgatctc tacgatcaag aagatcaaag aagaaagtca attgaccgtt atatctatca
    21601 ctcatgatat tgatgaagca gctaatgcca atcggatact agtgatgaga caaggcgaac
    21661 ttgtccgtga aggtacacca aaagaaattt tttctgctgg tcctgaactg atcgacttag
    21721 gtctagatct accatttcct gaaaaactga agagcgcact gaaagaacgt ggggttgatg
    21781 tgcccagtga atatatgaca gaagaaagga tggtggattg gttatggaca tccgttttga
    21841 acaagtagac ttcacttatc agccgaatac accatttgaa caaagagcct tatttgacat
    21901 caatatgacg atcaaagaaa acagttatac tgcattagta gggcataccg gaagcgggaa
    21961 atcaacctta cttcagcatt tgaatgcgct tgttaagcca acaagcggta cagtccatat
    22021 tggagaacga gatattcagc cggatacgga taataagaat ttaaagccca tccgaaaaaa
    22081 agttggcatc gtctttcagt ttccagaagc acagctattc gaagaaacgg tagcaaaaga
    22141 cattgctttc ggtcctaaaa actttggtgt cagcgaagaa gaagcactag tcctagcaaa
    22201 agaaacatta gaacaagttg ggctggatga aagctatttg gaacgttcgc catttgaact
    22261 ttcaggaggg caaatgcgta gagtagcaat cgctggtgtg cttgccatga ggccggaagt
    22321 acttgtattg gatgaaccaa cggcaggact tgatccccag ggcagaaaag aaatgatgga
    22381 gatgttttgg cgtcttcata aggaacagca gatcactatt gtattagtta cgcatttaat
    22441 ggatgatgta gccaattttg cagattatgt ctatgtgttg gaaaagggac gaatcgttaa
    22501 tagcggggag ccgcaagagg tctttcaaaa cattgaatgg ctaaaagaaa aacaactagg
    22561 cgtacctact gccaccgagt ttgcagaaga attaatggct aaagggatga actttgctac
    22621 cttgcctttg acagctgaag aattagcaga cgctatcgtc cattatgctg gaggaaatgc
    22681 ccatgatgaa taaattgata tttggtcgtt atatgcctgg agattccttg atccatcgat
    22741 tggatccccg agctaaatta ttagccagtt tttattttat cggaatcatt tttttagcaa
    22801 ataattggga aacgtacctt ttgttggcat ttttcacatt actttctgtc ttcttgtcaa
    22861 aagtagattt gaaatttttt atccgaggca ttcgcccatt gatctggcta atcctcttca
    22921 ctgtagcttt gcaggtcttg tttacaagtg gcggagaaac ttattggagt tggggtgttt
    22981 tccatatcac tgaatttggt gtgatgaacg gcctctttat tttctgtcga ttcgtgttga
    23041 tcatttttat gtcgactcta ctcacgctta ctacaccgcc tttggaatta tcggatgcga
    23101 ttgagtactt gcttcgtcca ttgaaagccg tacggttccc agtccacgaa atttcattga
    23161 tgctgtcgat tgctcttcgt tttgtgccta cattgatgga cgaaacagaa aagatcatga
    23221 acgctcagcg cgctcgcggt gttgattttg gtgaaggaaa cctagttcag aaaatgaaag
    23281 cagtcattcc tttgctgatt cctttatttg tcagcagctt caaccgtgcg gaagatcttg
    23341 cgactgctat ggaagcaaga ggctacaaag gtggggaagg aagaacgaaa tatcgtgtat
    23401 tgcattggca taatagagac acgatggtta tcattgcttt tgtattatta actgtgctac
    23461 tgatcttttt aagaggataa acgttcagtg ggccgctatc tattcttttc ttgctgatct
    23521 gtttgcaaga aaggatgcaa gcagtgtatg acaagaaata ttagggtctg tggcagacta
    23581 aggtcacagg cctctttctt ttatctgaaa agaaagaacg aaaaaatttt atagaaaaat
    23641 cattattcca gataaccttt taggaacaaa ggagagaaaa acatggtacg ttacaaagca
    23701 atcattgcgt acgacggaac aaattttaat ggattccaaa aacagccaaa tgggcgtact
    23761 gttcaagaag aagtagaaaa aacattacaa aaaatggcaa atggaaaaga aatcacggtc
    23821 tttggttcgg gaaggacaga tgccggagta catgcgatcg ggcaagtaat ccattttgat
    23881 tatccagagg agcgtccgtt agaacgaatg cgtttcgcgc tagataccca gtcaccagag
    23941 gatattgctg taagacaagt agaaattgtt tcagaagact tccacgcaag atatttggtc
    24001 aaagaaaaga cgtatcaatt tcgagtggat atagggaaac cacgcagtcc ttttcgacgc
    24061 cattatgcaa gttattttcc ttacccactt gatttggaaa aaattcagcg ggcgcttcct
    24121 gatttattag ggactcacga tttcacctct ttttgtgcat caggaagctc gatagaggat
    24181 aaaatacgta cgatctacga ggctaagatg gaggtaaatg aaacaaaaga cgaattgttg
    24241 tttacattta ggggaaatgg cttcttgtat aagatgatac ggatcttagt aggaacgctt
    24301 ttgaaaattg gcaatggccg attgcctgaa gatagtatcc cagatattat tgcgaaaaaa
    24361 gatcgtaatg cagcaggacc tacagcacac cctgaaggac tttatttgta tgaagtgaaa
    24421 tatgaataag aggttatgat agaagtggtc agcttcaaga aataagaagg tatttacgaa
    24481 aattacttct caaaattttg caaaatttcg gcttattttc gaagaagcta cttctggaac
    24541 accgtttaag gaagaggtcg tgaaatcagc gttttgacct gagtattaga gaaacaaacg
    24601 ggaaaatagc tcctcatatt ttgccgtttg ttgagctaat accgaaggtc agctgattga
    24661 acaccgttta agaaagaggt cgtgagcctg tcatttaact ctgagtcaca aagagcaatt
    24721 tcaaaaaaca gcttctcatc tttgatgaat atcgtgactt gtggacgagg cgttgataag
    24781 tgaatcatct ttttgttacc tattttttct gtaaccaaaa aacgatggaa cgttgttttg
    24841 attgcccttg gtgcggacag tctgaacagg ttccatcgtt tctttatttt ctacgtcttc
    24901 ttctgtgtgt gtttcgtggt tgttcttcta ttgctggatc aatcgtgcca taaaaggggc
    24961 gattgcggtc aaggtaccag acataaagaa taaacaatgc aatacatagg acaaaaagga
    25021 ttgcacctat cgtaaatcct tcaggcaagt aactgaaagt gacagtatgt ttacctgctg
    25081 gaacttttat catcaagaat gcgtctttga aattgctgac cttgactggt ttcccatcaa
    25141 ttttagcttt ccatcctttg tcataaggaa tagttgtcac caacatggaa tcttcagcgg
    25201 tatttacagt cccagaagct tttctgccag tggcttccat ttcgacacct ttttctttga
    25261 tctgattcat tgcggcttga taggctacaa catctagacc aacgacttta ggctccatga
    25321 aacttatttc tttcgtccca taaaaacttg cagtaaatgt cactgttgtc tcttgaggat
    25381 aatagccaag atcatagtat tgaccagaaa tgttgatttg cgtttttcgc gatgtaccat
    25441 tgacagtgat cgtcgcacta gaactttcta attgcgcaaa attggttggg aacaaactta
    25501 agtaagcttg tgtatttgca ggcacatgga cttcccaagt gagctctttt ggctggttat
    25561 ctgctgtttc tgagtaagtg acgccagtcg ttgtctttgt gatcgtcgta ttcaactgat
    25621 tcttcaaagt aggtgtatag aatgtaaaat actgttcatt tagaccagac aatgtattga
    25681 tcaagtttgt ctgactggtc aaattatctg tcactggctg ctcaacatca ttaacggaca
    25741 acggtgcagt aaatgctagt ggcaatgcat tgacattctg atacagtgta tagtcgccgc
    25801 tttgaccagc ttggcggaag ccatatttac tgaacgtgct ttcgttttta gaaatgttat
    25861 atttgattcc tgtaaaccca tccatcagca aagtattatt gttataacgg atattcaaat
    25921 ttgtccctct tgaacggaaa cctaatttat ccaggtaaga ggaagaatta cgatttctta
    25981 tagaagaaaa caaactgata ccactgtaac catagttgat cgaatcgttt gcagatactg
    26041 gatccagatt ttccaagcgg taaaacgagt cggaatcttt ttttgtttca tttacaagag
    26101 ctttcaagtc aggataagga tcagtatata aactgcggga agcataattc caatcatcaa
    26161 gaatgccatg gatcatactg ttcgtattga ccagtgcttc agcagacatg atcaataata
    26221 acaatatact cagatgattg aatgaaagtt ttttatgctg ataaaatccc acagcaaaag
    26281 cataaatccc taagaaaacc actgtcaata caaaggaagt catcgtcaca taggtgtagc
    26341 ttccttcagg tttgatgccc catgccaccg caaagagagc agctacgacc aaaatgattc
    26401 ctaacaacag cccacgatcg tcttgttcta tcttttccca tccttttcct gcaagcagga
    26461 gcactaagaa agagaacaga taggcataac ggaataaaaa catattcggt gcatgcatac
    26521 catgccagaa caaattcaat ggaacaagat aaaaacttgc gataagtatg gcgaaaagac
    26581 tgccgtacaa aaatttattt ttcaacggta ctttccgact ggcaaaataa aacagacaga
    26641 ggactaatgg tagcagacct gcgtaaacga acggaatcga tccgtatttt gtcgtgtcat
    26701 aaacaccaat catatttttc atgattagat ccagataaga agtcgcttct gttttcaacg
    26761 tagtgatctg actcagtgcc tcgccatttg accgaagatc cagcactgct ggcaatacaa
    26821 tgatcattga agcgccgcct gccagtaaag aagtgatacc ataaggaaca atcgtttttt
    26881 tatattctga ccagtttgtc aatagacggg cgataaaata taagaaagaa aatacgccaa
    26941 tcataaaacc catataaaaa ctggataaaa acaagagtaa ataactgata aataaaagtt
    27001 tcggccgttt aagatccata acacgatgaa tccccaaaat cactaatgga agataaaaaa
    27061 atgcatccag ccacatgatg atctccgaat gtgcagtgat aaatgagatc aatgcgtaac
    27121 tgacgctaag tgcaacatgc ccccagcgag gaatcttgaa cgtacgtgca agaaaccaaa
    27181 aagccaatcc ggcacagccg accttaagca aagtcagaac atacagtgca tctggcatca
    27241 tctggtttgg aaaaaagaac accagtggcg tgaagatccc gcctagatag taagaaatta
    27301 aagataaata attcaatcct agagaagcat tccatgtata aaaaatactt tgctttccaa
    27361 gaagaacatt tcggaagctg gcatgaaaat tagaaaactg tgaaaaggca tcacttgcca
    27421 aaatacttct gctgcttcca ggatagattc cgatacttag ataaacaagt gctaaaatca
    27481 aaaacggaat caggaaacta gctgctgcgt agcgtccgtt ttctctaaag aatgacttta
    27541 aatttttttt catatttatt ttccaccaaa tttctatgaa gttgtattca gtttatcata
    27601 tccttgtttt tctctgctta aaaagagtct agttttcaca aaaaaataaa atttagaata
    27661 aataacttca taatttgttc gtataacaaa aataaacgca aaaaaagggt aggaatcaaa
    27721 agtcccaccc ttaaaaattt ttattaaata aaaaaccgtt cactatctga acggtccaag
    27781 tatcattcaa ttaaacgcgt tcaacttttc ctgatttcaa agcacgagtt gacacccaaa
    27841 cttttttagg ttttccgtcg accataacgc gaactttttg taagttaggt ttaacagtac
    27901 gttttgttga gttcatagcg tgtgaacggt tgtttccact ttttgtcttg cgacctgtaa
    27961 agtaacaaac ttttgccatg gtaatttcct cctttgcctt gatttggagc aatagaataa
    28021 ttcagctcat accagactaa catatcatat agaatgggaa tttgcaagta cattttcata
    28081 gatacaattg acaattgaga agaataattg taaattaaac aaggttatac ctgaaatttt
    28141 gcaaggtttt tgagtacttt gggtaactgc cttttatttc aagttgcgct atgataaaat
    28201 atgatagaag aaaaatggga gttttttacc cgttaaggag gctcattcat ggctgtaaaa
    28261 attcaaacgt cagctggaac cattgaaatt accaatgatg taattgcaac agttgttggt
    28321 ggcgccgcga cagatgtgtt cggtgttgta ggaatggcca gcaaaaatca aattaaagat
    28381 aatattactg agattttgcg taaagaaaat tactcaagag gagtagttgt ccgccaagaa
    28441 gataatggta ttgctgtaga tgtttatacg attatcagct atggtacgaa aatctctgaa
    28501 gtttcccgca acgtccaaga aaaagtgaaa tacaatctag aggcattatt aggcgtaact
    28561 gccaattcag ttaatgtctt tgtacaaggt gttcgtgtac tgccagacta ggcaggagac
    28621 tggctggtaa ctcagcagtc gatctgaagg aggattatct aggtgagtgt aacagaaata
    28681 agtgcaagcc agttccagga aatggtccag gcaggtgcga atcgtctgca agtaaatgca
    28741 gaatacgtca attcattaaa tgtattccct gtgccagatg gcgatacggg aacaaatatg
    28801 aatctatcta tgactagtgg agctaaggca gtagtagatt caacctcaga aaaagtagga
    28861 gaattagcag caatgctttc aaaaggattg ctgatgggtg cgcgcggaaa ttccggcgtt
    28921 attttgtctc aattgtttcg tggattttct aagcaaattc cagatgttgt ctcattaaat
    28981 gcttctgatc ttgctgcagc cttcactcat ggagttgaaa ctgcgtataa agcagtaatg
    29041 aaaccagtag aaggaacgat tttgacagta gctagagaag cagcgaaagc tggagaaaag
    29101 aaagcaaaaa gtactgatga tgtcgttgaa gtaatgacag ctgttgtaaa aggagcaaag
    29161 cgtgctttag ctaaaactcc agacttgctt ccagtcctaa aagaagtcgg tgtcgtagac
    29221 agtggagggc aaggactgct gtttgtttat gagggctttt taagtgcatt gaatggagaa
    29281 ttccaagcgg atgaaacata tgaaccttct ccagcagaaa tggatgatat ggtcaatgca
    29341 gaacatcatc gcagtgtcca aggtcaaatg gcgacagaag atatccattt tggttactgt
    29401 acagaaatca tggtaaaaat cggagaagga cctacagtcg atagtacatt cgattacgaa
    29461 gaattccgta actatttaga tggtatagga gattctttac ttgtggtcaa tgatgacgag
    29521 atcatcaaag tccacgtgca tacagaaaac ccaggagaag tcttgaatta tggacaaaaa
    29581 ttcggttcat tagtcaaaat caaagtcgac aacatgcgct tgcagcatga gacgattttg
    29641 gaacacgatg aagaagtgaa cgagtttgcg aaaaaagaaa taccacgtat cccgtatggt
    29701 atcgtagcga tcgctgctgg taaaggcgtc caagagctgt ttgaaagttt aggcgctaat
    29761 tatgttatca gtggtggaca aacaatgaat ccaagtacgg aagacattgt taaagcgatt
    29821 caagaagtaa acgcagataa agtgattgtc ttgccaaaca ataagaacat cttcatggca
    29881 gctgatcaag cagcagaagt agcagatatc ccagtagcag ttgttccttc aagaacgatt
    29941 tcccaaggat tgacagctat gctttcattc aatgatcaag cttctttaga agaaaacaaa
    30001 gaaacgatga cagaaatgtt gtctagcgtt gtgagcggtc aagtcactca cgcgatcaga
    30061 gatacctcaa ttgacggtgt agagatcaaa gaaggagact ttttgggcat gatcgatgga
    30121 aaaatcctga tctctaaccc agatatcaca gcaacagcgt taagtacact agaacaaatg
    30181 atcaatgagg acacagagat cgtaacgatc ttggcaggtg atgaaggaac agttgaacaa
    30241 gcaaatgaat ttgctgagaa actaacagaa aaacatcctg atttggaaat cgagatccac
    30301 caaggagatc agcctgtcta tccttatcta ttttctgctg aataatttct gtgtcagaat
    30361 atctttctaa cacagtattc attcataaaa ggccttcggt tagtgatcag gtatgatcgc
    30421 tgaccaagtc ctttttttgt taaaggaggg aggaaaaatt tatgcgttct ttagatgatc
    30481 caatcactat gctggcagga gtcggagaaa aaagagcagc tagtcttgcc agcttgggca
    30541 tccaaacgat tgaagactta ctgacttatt atccttttcg ctacgaagat attcaggaaa
    30601 gaaatctaaa cgagatccag gatcaagaaa aggttacttt gaaaggaatc gtagtctcgc
    30661 ctcctgtgat gaatcgattt ggttataaaa aaagccgatt gcaatttcgt atgatgcaag
    30721 aacatgatgt gttcaacgtt tcttttttta atcaacctta tctaaaagaa aaagtcattt
    30781 tatcggagga aatcgccgta tacggtaaat gggatgcaaa gcgtaaagcc ttgaacggga
    30841 tgaagatttt aggttctcaa acaatggatg acttttcgcc gatatatcac gtcaacaaat
    30901 caattcgtca aacgacatta gttgatctaa tcaaaaaagg gtttcaagaa tacggcacat
    30961 tgattgaaga aaatctgcca aacaaccttg tggagaaata tcgactgctt gaccgagctt
    31021 ctgctgtaag aagtatgcat tttccaaaag accacgaaga aaaccatcaa gccaaacgac
    31081 gtgtcgtttt tgaagagttc tttttatttc aaatgcgtct tcaaggattg aaaaaagcag
    31141 aaaaagcaga aacgaatggt ttggagatcc tttatgatgt ccaaaaattg aaacaattta
    31201 ctcaaaagct accttttgaa ctgacaaatg cacaaaaacg tgtaacgaat gaaatctgtc
    31261 gggatcttcg cagtccgcag catatgcagc gacttttgca gggagatgta ggtagcggaa
    31321 aaacagtggt tgccgcgatt gcgttatacg ctaccgttac agcaggtttc caaggtgcgt
    31381 tgatggtgcc tacagaaatc ttggcacaac aacatatgga aagcttgcaa cagctgtttg
    31441 atcccaatga agtaaccatc gcattgatta cggggtcaac gaaagcaaaa gaacgacgtg
    31501 agctccttga aaaactagag caaggggaaa ttaacgtcgt gatcggcaca catgcattga
    31561 tccaagatgg agtcgaattt cagaatttag gtctagttat tacggatgag cagcaccgtt
    31621 ttggcgtgaa ccagcggaaa gtacttcgtg aaaaaggctg gcgaccagat gtcttattta
    31681 tgacagcgac tccgattcct agaacattag ctattacagc atatggtgag atggatgtat
    31741 ctatcattga tgaacttcca gctggacgta tcccgatcga aacacgctgg gtaagaacac
    31801 ctcaattgga cagtgtactg gattggacga aaaaagaact ggcaagagga catcaaatgt
    31861 atgtcatctg tccgctgatt gaagaatcag aagcattaga tgtaaaaaat gcagtggaaa
    31921 tctatgaaaa acttcgtgaa ctatttgcac caaaatatga agttggcttg ttacatggta
    31981 aaatgaagaa tcaggaaaaa gaagtaatca tggaagcctt caaagacaac cagatgcaga
    32041 tattagtttc gactactgta attgaagtag gggtaaacgt gccgaacgcg accgtcatgc
    32101 tgatcatgga tgcggatcga tttggattgg cacagctgca ccaacttcgt ggacgtgttg
    32161 gacgcggaag tgatgcttcc tactgtatct tagttgctaa tcctaaaaat gaactaggtg
    32221 tggaacggat gaaaatcatg acagagacca ccaatggttt tgtactaagc gaaaaagatc
    32281 tggaattacg tggtcctggt gaagtatttg gcttccgtca atctggtctg cctcaatttg
    32341 cgattgctga cttggtgacg gatggaaatg ttttggaggt agccagagaa gaggctgcag
    32401 ccctttggca aataaaggat tggcagatgc ttcctgagta tcagccttta gcgcaaagcc
    32461 tccaaataga aaatcaggat aatcgttatt tcgattagca gactgtgcta tactttatac
    32521 tgatgacgga aaaaggagtg gaaacaatga aaattgccgt agatgcaatg ggcggagatc
    32581 acgcacctca agcaattgta gaaggcgtgg ctttagcgca gcaagatttt ccagaagtag
    32641 aattcttact ttacggaaaa gaagcagaaa tcaagaaata cttaacaaat gaaaaaaaca
    32701 tcacgattat ccatacagac gaaaaaatca atagtgatga tgagccagta aaagcaattc
    32761 gacgaaaaaa gactgcatca atggtccttg ctgcacaagc agtgaaaaac ggtgaagcag
    32821 atgctgtatt ttcagcaggg aatacaggcg cgctactagc agcagggttg ttcatcgtag
    32881 gacgtatcaa aaatatcgaa cgccctggct tgatgtctac cttgccagta gtagggaaag
    32941 aaggtgccgg tttcgatatg ctggatcttg gcgctaacgc agaaaacaaa ccagaacatt
    33001 tgttgcaata cggtatttta ggttcttttt atgcacgtaa agtccgaggt atcggacgtc
    33061 ctcgtgtcgc actcttaaac aacggaacag aagcaacaaa aggtagtgaa gtgacgaaaa
    33121 aagcctatga actccttcag aatgaaacaa gcttgaattt tattggaaac gtagaagctc
    33181 gtgagctact caatggtgtg gctgatgtag tggtcacaga tggatttaca ggcaacgctg
    33241 ttttgaaatc tattgaagga acagcaatga atatgatgaa tctattaaaa tctgctattc
    33301 taaatgaagg gatcaaagga aaaatgggcg ctatgctttt aaaagacggc ttacgttctt
    33361 tgaaagcaga aatggattat tccaaacatg gcggtgccgt tttgtttggc ttgaaagcac
    33421 cagtcattaa aactcatgga gcaacaggcc ccgatgctgt tcgctatacg atccgccaaa
    33481 tccacacaat gcttgagaca gatgtagttg gacaattagt cgaacaattt gaaaaaagcg
    33541 aagaatagta tttggatatc tgaagcgatc cgttccattg aaaaaaaggt ggacattcct
    33601 gaaaaatgcc agtaaaatta gccatggtgt aggtaattga caagtgtatg attcttggag
    33661 gtgaaaaagt tgactcgcga agaagtattt aacaaagtag cgaaaattat ttcaaatcat
    33721 tttgagatag ataccgataa agtgacggat gaattgaaca tcaaagatga tttaaaagct
    33781 gattcaatta gtattatgga attcgtttta gagcttgaag atgaattcgg tacggaaatt
    33841 tcagatgaag acgctgaaca aattgaaaca gtcggtggcg cagtagatta tatcagcagc
    33901 catcttaaat aatttcaaat aaaagcaaag aaggataaaa agctgcatgc agctttttat
    33961 ccttcttttt ttaatctttt tgacacgtaa aagtcatttt tctgataatt ctggcgataa
    34021 acagaaatta tgttgcaaag taaagcggtt ttctatataa ttattaataa ttcattacac
    34081 aaagataaga ataacctttg ttataaaacg atttattctg tgtaatgtcc ttttttatta
    34141 agaaaaactt ccatttagga agcagagagg ggtattcgat tgtccgataa ccaattatta
    34201 gaagttcaga acctacatac aggattccga ctcaaagatg actattacga tgcagtagat
    34261 gacgtttcat ttactttaga caaaaacgag attttagcaa tcgttgggga atctgggtgc
    34321 gggaaaagta ccttggctac tacgattatg ggattacttg atcctaataa cacaaaaatt
    34381 acaggtgaga ttttatataa cgatctgaat ttaatcgacc tgaacgaaac gctctataat
    34441 aaaatccgcg gaaatgatat cggaatgatt ttccaagatc cgttgtctgc attaaatcct
    34501 ctcatgagaa tcgaagacca gatcaaagaa ggactttcct atcacacaaa gatgaatgca
    34561 gaacagcgtc aagctcgtgc actagaattg ctagaacaag tagggattcc taatcctgcg
    34621 agagttggac gccaatatcc ccatgaacta tcaggcggta tgagacaacg tgtcatcatc
    34681 gcaatcgcaa tcgcctgcaa acctccaatc gtcattgcag atgaaccgac gacagcccta
    34741 gatgtaacca tccaagcaca gattcttgat ttactgaaag accttcagga agaaacaaaa
    34801 acagggatca tcttgatcac tcatgactta ggagtcgtag cagaaatggc tgatcgagtg
    34861 gcagtgatgt atggcggaca gttcgttgaa gtagcaggtg taaaagaact gtttgatcat
    34921 cctaagcatc cttatacacg ctctttactg aactctatac cacaagaagg aaatcatgat
    34981 gcagaactcc atgtgatcga aggtgtcgtt ccttctctga aaaacatgcc tcgtaaaggt
    35041 tgtcggtttg caccacgtat tccatggata ccagcaagcg atcatgaaga agagcctatc
    35101 cttcatgaag tcgcaccgaa ccacttggta cgttgctcct gctataagca tttccacttt
    35161 agagacgaaa aaggagaggt gtagatgaca gaattaatca caatcaaaga cctgaaagtt
    35221 cattacccta ttcgcagtgg attcttcaat cgagtaacgg atcatgtata tgctgtagat
    35281 ggtgtggatt ttattatcga aaaaggaaag acatatggtt tagtgggaga gtctggctct
    35341 ggaaaatcta ctacgggaaa agccgttgtg ggattagaaa aggtaacagc cggacaaatc
    35401 atgtatgaag gaaaagatgt aacgaagcga agcaatcgca aaaaaatggg ttataacaag
    35461 gatgtgcaga tgatcttcca agattcaatg tccagtttga atcctaaaaa gcgagtgttg
    35521 gatatcattg ctgaacccat ccgaaatttt gaacggttaa gcgatcaaga agaaaagaaa
    35581 aaggtaaaag gactgctaga tatcgttggg atgccggaag atgcgctata taaatatcct
    35641 catgaatttt caggcggaca acgtcaacgt ctaggagtag cccgtgctgt tgctaccaat
    35701 ccaaaactga tcgtagccga tgaacctgta tctgctctgg atctatctgt tcaagcgcaa
    35761 gtattgaatt tcatgaaacg aatccagcaa gaatacggcc tcagctattt attcatttca
    35821 catgatttag gtgtagtaaa acacatgtgc gacaatatcg caattatgta caaaggtcga
    35881 tttgtagaaa tcggtacaag agaagacatt tataatgacc cgcgacatat ctatacgaaa
    35941 cgtctgcttt cagctattcc gcaaatcgat gtagaaaata gggaaagcca caaagaaaat
    36001 cgacgaagag tagaacaaga gtatatccaa aaccaaaaag aatactatga tgcgactggt
    36061 cgagtctacg atttgcgtac gatcacaact acacacaaag tggcgttgaa agatggaggt
    36121 gcaagctaat gtggaaaacg attctgcgac gtgttttatt gatgatcccg caagttatta
    36181 ttttaagtgt tctgatcttc ttattagccc aagcgatgcc gggggatcca tttaccggtt
    36241 tgatcaatcc aaatcaggat ccggcagtga tcgaacagat gcgacaagca gctggcttga
    36301 atgacccatg gtatgtccag tacttccgtt ggatcggaaa tgctttgcaa ggcgattttg
    36361 gtcaaagttt cttatacaaa cgctctgttg ctgacttgat cggcgaacgg atcatcaaca
    36421 ctttatatct atcgatcttg acagttgtcc ttacttattt gattgctgtg cctctgggga
    36481 tgcttgctgg ccggtatcaa aattcaatct tggataagat tgtcgtaatc tacaacttct
    36541 ttagttttgc tgttccttta tttatcttcg gcttgatcat gctatttgtt tttggttatc
    36601 gtttaggctg gttcccaaca agtggatcac aaacactagg tttgcaaggt ggatttatca
    36661 ctcaatggat agaccgtttg aaatatattc tgttaccatc aattacccaa gcatttttgg
    36721 cgactgccgt cacaatccaa tatctgcgaa gtgaagtaat cgattcgaaa tcgctcgatt
    36781 ttgtcagaac agcccgttcc aaaggggtac cgacgaataa agtattcagt cgacatattt
    36841 tccgaaatgc agcgttgccg atggcttctc aaatggggta tgaaatcact tcgttgattg
    36901 ctggttctgt agttatcgaa aagatttttg gttatccggg agtcggaaaa ctatttattg
    36961 attccatcgg ccaacgggac tataccgtga tcacatcctt agtattgatt ttaggaatcg
    37021 cgacgctagt ggggacatta ctttcagata tcatcatgag tatcgttgac ccgcgtattc
    37081 ggattcaata aaaccaatca gaaaggagaa tggatcgatg agtgaaaaaa acaatacagc
    37141 agttcaagaa agtattcctc ctatggggat acgaatgatt gctcgagaat ttaaaaaaga
    37201 taaaattgct attttttcat taggtttgct agtggtttta ttattagtga tctttatcgg
    37261 tgcgatgctg accgatcaag acaaagtgat gtatgttagt atcttcgaca aatacgctgc
    37321 accaggaaca gtttcgacac aaggacaaaa gttcattctg ggagcagatg aaggcggacg
    37381 tgatgtatta ggacaattga tcataggtgc tagaaactct gttacgatcg gatttgcgat
    37441 cacgatcctt acttcgatca tcggggttgg attagggatc atctctggct actacggagg
    37501 gatcattgac aacatcttga tgcggatcgt tgattttatc atgattctac cgatcatgct
    37561 gatcattatc gtcttcgtat cgattatttc cagatacaat gtctggtcct ttatattcat
    37621 catgagtgca ttttattggg tagctaaagc ccgattattc cgaagcaaga cattatctga
    37681 agcaagaaga gattatgtca gtgcctcaaa aacaatggga accaatgatt ttaaaatcat
    37741 gttccgcgaa atcatgccga atctaagttc attaatcatt actaatttga cgatgaactt
    37801 tgcggcaaac atcggtatcg agacaacttt gactttctta ggtttcggct tgccggcaaa
    37861 tgtacctagt ttaggtacat tgatcggtta tgcaagtaac ggagaagtct tagtgaatcg
    37921 gcaatggatc tggttacccg catcaatcct tattttagtt ttgatgttga gtatcaatta
    37981 tgttggacaa gcattcaagc gttctgcaga tgcgcgccaa cggttaggct agtatagaag
    38041 cgaaggggga aataggaatg aagaaaacga tttttggatt tgcagcgctg atgtctgctg
    38101 tcgttcttgc agcatgcggg ggcggaggta cagatacctc tggaaacaac tctggaggca
    38161 acggcaataa caaagaggaa ttaacttttc caattgcaac aaaaaataat gatgatgcaa
    38221 tcgaagacgg cgaattagaa gctgcggtcg caacggacag tcagtttaaa ggattgttcc
    38281 agtgggagtt ttaccaagat tcatatgatg cagcttttat ggctccttct catgaaccgc
    38341 tatttgcaaa cgatgacgat ttcagaatca cagacgacgg agctgcaacg cttgatctag
    38401 atgaagatac gaaaaaagcg acaatcaaag taaaagacaa cgtcaaatgg tcagatggtg
    38461 aagatgtaac ggcggacgat gtgattttcc cttacgaaat cattgggaat aaagattaca
    38521 ctggtatccg ttatgacgac actttccgta acatcgtagg tatggaagaa tatcatgatg
    38581 gaagtgccga cacaatctcc ggaatcaaaa aaatagacga caaaacagtt gaaatcgaat
    38641 ataaagaagt aaacccaagc atgcttcaat cgggtggtgg tatctggtca tatgcagcac
    38701 caaaacatac gttagaaggt gtagcaatca aagatatgga atcaagcgat caagtacgta
    38761 aaaatccagt gacttttggc ccttattaca tgagtaatat cgttgcagga gaatcagtag
    38821 aatacttgcc aaacgagcac tactggaatg gtacgcctaa attgaaaaag atcacgatga
    38881 aatctgtacc gatggcaagt gcaactgaag cattgaactc taaattatat gatatgattt
    38941 tccaaatgcc aacagatact tacgatacct ataaagaaat tgctggctat acaaacttag
    39001 gccgtgaaca aacttcttat acttatctag gattcaagtt aggtaaatgg aatgcagata
    39061 caaagagtgt ggaatacaat ccagattcaa aaatggctga taaatcatta cgtcaagcaa
    39121 tgggctatgc attagataat aatgcagtag gtgaacgttt ctatgcaggt ttgagaagca
    39181 atgcgacttc attgattcct ccagtattcc agtcatacca tgatgatgag atgaaaggat
    39241 tcacacaaga tctagacaaa gcgaaaaaac tattagatga tgctggctac aaagatgtgg
    39301 atgacgatgg tttaagagaa gacaaagatg gaaataaact aacaatcaac tttgcttcga
    39361 tgtccggtgg ggaaacagcg caaccattgg cagattacta tatccaacaa tggaaagaaa
    39421 ttggtttgga tgtccaatac acaacaggtc gtctgatcga attcaattct ttctatgata
    39481 aattagaaaa cgatgatcct gaaattgatg tttaccaagc tgcttggaat acaggaactg
    39541 atccaaatcc aagtggacta tggggaccaa atgctgcgtt caactacact cgttatgaat
    39601 cagaagaaaa tacaaaattg atcaacgata tcagttcaag caaagcattt gatgaagagt
    39661 accaaaaaga agcatatcaa aaatggcaac aatatgcatt tgaagaagca tttgcgattc
    39721 caacgttgtt ccgtaatgaa gtattgccag tcaacgaccg tgtcaaagac tgggattggt
    39781 cttatgatgt accaaaccca tgggcaaatg tttctgttac agcagattca cgttcataat
    39841 cactaaaaat gaccgaaaaa gggcgatgtc ctttttcggt tttttgatat ttttctgttt
    39901 atttctctaa tattcaggtc aaggcgctga tttcatgact tctccaataa acggtgttca
    39961 aagtccagtt tctcggtatt aagtcaaatt tatgcaaaaa tatggaaagc cattttcaca
    40021 aaattttttc ttcatactcg aaactaaacg aatttttcac aacttctcgt caatcactag
    40081 gattattaaa gctttactta ccttttgacc gaaccatttc aaatttgaca aaaaaccagt
    40141 ataataagga agtatcgaaa aaatatccat aaaaggaatg tggaaaatgg acaaccagct
    40201 gacaaaagaa ctaaaagaaa actataacat cgtttttcac gatctaaatt tgcttgaaca
    40261 agcttttacc cattcatcct atgtgaatga gcatcgcaat ctgcaattat cggataatga
    40321 gcgacttgaa tttttaggag atgccgtttt agaactgatg gtttctcagt atttattccg
    40381 tttatatcct catttgccag aaggaaaatt gacaaaaaca cgagctgcga tcgttcgcga
    40441 agacagcttg tcgaaatttg ccaaagaatg tcactttgat caatatgttt tgttgggcaa
    40501 gggagaagag aattcaggag gacgtacgcg accagcattg ctttgcgacc tattcgaagc
    40561 ttttttaggc gcgttatatc ttgaccaggg attcgacacg acccatgcat tcatcgaaaa
    40621 agtgattttt cctaaagtca aagcaggtgc tttttcacat gagatggatc ataaaacaaa
    40681 actacaagaa gtcttgcaaa aatcaggtga tgtatcaatc gaataccgat tgatcaatga
    40741 agaaggtcca gctcatgaac gagtattttg gatcgaagtt tatgtagatg atcaattgat
    40801 tggcactgga caagggaaat cgaaaaaatt agcagaacaa gctgcggcgg aaaatgcatt
    40861 ggcagcactg taaaagtaag tgagggaaag ctttgtattt gaaacgaatt gaaatagccg
    40921 gttttaaatc atttgcagac aagacagtca ttgattttga aaatagcgtc acagcagtgg
    40981 ttggaccaaa tggcagcgga aaaagcaata ttacagaggc tatccgctgg gtattaggag
    41041 aacaatctgc taaaagtctg cgaggcggaa aaatgccgga tatcatcttt gccggttccg
    41101 atacccgtaa gcagctgaat attgcagaag tcacagtgat tttagacaat agtgatcatt
    41161 atctgccatt ggagtacaat gagatcagtg taacccgccg ttatcgacgg actggggaaa
    41221 gcgagttttt catcaataaa caaagctgca gattaaaaga tatccaagaa ttgttcttag
    41281 attctggatt aggaaaagaa tcgttctcaa tcatttctca aggaaaagta gaagcgattt
    41341 tcagtagtaa accggaagac cgtcgtggga tctttgaaga agcagctggt gtcttgaaat
    41401 acaagcagcg gaaaaagaaa gcagaacaga agctttttga aacagaagac aacctcagcc
    41461 gcgtccaaga catcatccac gaattggaag aacagttaac tcctttggcc gcccagagtg
    41521 aggcagcaaa ggagttttta cggctaaaag aaacactgac tcaaaccgat gtctctttga
    41581 tggttgctga aatcaagaca gcaaaaaaag attgggacaa caaacaagca cagcttgcga
    41641 aattcaatct agaattaggc aaactatctg agtcgatcca agaacaagaa tccattttgg
    41701 cgaagcagcg taaagaaaat gcgcaagccg atcgtctgat cgaaaaaaat cagcaagtat
    41761 tattagatct ttcggaaaaa ctgaagcaga cagaaggaca aaaagatgtt ttgcaggagc
    41821 ggacaaagca tacacaaaaa agctcgcaag aatatcaaac ttcattagca gaagcacaaa
    41881 aaaaggttaa acattttgaa aagcttcaag aaagcttgat gaaagcagca gcagaaaaag
    41941 aaacagagat ccaaaaagct gaagcaaatc tcataaaaac acagcaagaa ttagaaaaat
    42001 accaaaaatc aacgaaagaa ttattggcag aattaagaga tcaatatgtt gatttgatgc
    42061 aagaacaagc agctgtagga aacgaactga agtatctaga acgtcaatat atacaagaaa
    42121 cagcaaaaag caagcagacg ttagccaagc aatcggaagt agaagcatca gtagaccgat
    42181 tgatcttaca aaaagaagaa ttgacacaaa agcaggcgca gctaaaatca tctttaactg
    42241 aaacaaaaga gaagttagaa atgatccaac aaaacgggaa aaagttccaa gaagcattag
    42301 caaaagaaca gcctaaaatg tatcaattaa tgaatcaagt ccagcagcta cgtgctcgta
    42361 agaaaagcct tcaagaaatc caagaaaact attttggttt ttaccaaggg gttcgattgg
    42421 tcttgcagca taaacagcag ctttcgggta ttgtcggagc agtggctgaa ctgatcgatg
    42481 ttcctgcaga tttcacgtta gctatcgaag cagctttagg tggggcagcc cagcatgtca
    42541 tcgttgaaaa tgaaaaagat gctcggcaag ccatcacgta tttgaaacag caaagaggag
    42601 gaagagcaac attccttcca ctgacgacaa tcaaaccaag acaattaccg gctcatatat
    42661 tgacacaagc agcagctgta gaagggttta tagggattgc cagtgaacaa gtcagttatc
    42721 ccgatcaaat ccaaactgtg gttcaaaacc tgctaggaac gatcctttta gccaaagact
    42781 taactagtgc caatgcaatc gcgcaaacga tccgctatca atatcgagtg gtttccttag
    42841 aaggtgatgt gatgaatgcc ggaggatcca tgacaggtgg agcgaataaa cgaggaaacc
    42901 aaggcagttt gtttgtacaa aatcaagaat tgaaacagtt gactagtgaa tttgaagaag
    42961 cagataaaca actccaagca caagaaaaaa aagttcagga gctgcaacaa gaaacagctc
    43021 gtttagccga agaacaagaa gttttgcgta cacgaggcga acaattacgt tttgaagaac
    43081 aagaagcgac aaatcagcta caaaacatca taaatgaact tgaacgtttt gaaaaagaaa
    43141 agcaaatctc aacttttgag acacgtgaac tgcagcagtt tatcgaagat tacgaaaagc
    43201 aaacgaacga attgaaagac aaacaaacag atcttgaatc gcaacgacaa aaaatcgacg
    43261 aagaaatcaa atcgttaagt caagaaagcg accagatgga agccagaaga gcacaagtac
    43321 aaagtcaaaa agcacaagaa caagcagatc ttgctgtctt gaaagagcag tttaatcatc
    43381 tgcagatcca gctccgcggt gcccgagtcc aaaaagcaga ggcaaccgaa cgtcaagaag
    43441 cgatagaaaa gcagttggcg acattgacag cagacttttc tgatcatgaa gtcacagaag
    43501 aaagtttgga aaaacaaatt aacgaattat ctgctcagcg agaaacatta aaagccgagt
    43561 tggcaaaagc caaagagcag cgagatagaa ggcaaaagga gatcgataag cttgaagcag
    43621 tcttggcaga gcgtaatcgt gagcaaaaag cacgactgtc ggaacaatcc aaattagaag
    43681 tccaaaaaga ccgagctgaa atgattttag ataatcattt gacctatctg cagtcagaat
    43741 atcagctgac atttgagaaa gcttcccaag actatcaaga aacaaccgat atcgaagaca
    43801 gtagaacaaa ggtttcatcc ttaaaagaac agattgaaaa actgggacca gtaaacttaa
    43861 attcaatcga acaatacgaa caagtcagtg aaagacatac attcttagca acacagcgag
    43921 atgatctgtt agcagcgaaa aaccaattgt ttgaaacgat ggatgagatg gatgatgaag
    43981 tgcggacaag attcaaagaa gtatttgaag ctatccgtca agaattcaaa attgtctttc
    44041 caaatatgtt tggcggcggt aaagctgaat tagtactgac ggaaccaact gatttgctga
    44101 aaacaggtat tgagattgaa gtacaacctc ctggcaaaaa actgcaaagt ctaagtttgc
    44161 tttctggagg agaacgagca cttacagcca tcgcgttgct cttttccatt atccgtgtct
    44221 gtcctgttcc gttttgtatc ttagatgagg tagaagcagc gttagatgaa gccaacgtga
    44281 aacgttttgg tcgttacttg agcgatttcc aagatgacac acaatttatc gtagtcacac
    44341 accgcaaagg aacgatggtc gcagcagatg tactgtacgg agtgacgatg caggaatccg
    44401 gtgtatcaaa aatcgtttct gtacggatgg aagatatcaa tgaagaggcg aaaatcaacg
    44461 aaacgaaagt gtaggaacga aaatgatcaa attagtagca atcgatttgg acggtacatt
    44521 attaaatgaa caaaagctga tttcagatga gaataaacaa gcattagcac aagcaaaaca
    44581 gcaaggggtc aagatcgttc tatgtacagg acgcccctta gctgcgatgg cgcattatct
    44641 gcaagaatta ggactggtag atgaaggtga ctacagcatc actttcaacg gcggtttggt
    44701 acaaaaaaat gatactggtg aaatcatgga aaagaaagtg atggaagtat cagatatcca
    44761 acgcttatac aaactggctc agcaattgga tctgccacta gatgttttgt ctgacaatgt
    44821 ggttttacag ctgcctagtg ccccaaggaa gcaatccttg tacaatgtgt tgaataagct
    44881 gctgcaattc caaccagcgg atataagcga tattacagat gaatttgtgc ttaataaggc
    44941 agtaatcgct tatgaccaag aagaattaga tcctaaaatc aaagaaatac cagcagaatt
    45001 ccatgaaatg tatgagatca tcaaaacaag aagtatgctt ttggaattta tgccaaaagg
    45061 tgttacaaaa gcttatggta tttctttatt ggcaaaagat cttggtttga aacaagaaga
    45121 aatcatggcg atcggtgatg aggaaaatga tttaccgatg atccaatatg ctggactagg
    45181 cgtagcgatg gagaatgctg tgcctttcgt caaagaagca gcagatttcg tgacagccag
    45241 caatgaagaa aatggcgtag ccaaagtgat ccaaaaattt gtattagagt agggggagtc
    45301 aaatgggatt ttttgataaa atcaagcgtg cttttactgg cgaagagaaa acagaagaag
    45361 ttgaagtaca ggagaagtac gacaagggtt tagaaaagac gcgtaaaaca tttggtgaac
    45421 ggatgaatga gttgtttgcc aattttcgaa cagtcgatga agactttttt gaagaattag
    45481 aagaaacact tatcggtgca gatgtaggtt ttgaaacagc gatacgaatc accgaagcat
    45541 tacgtcaaga agtgaaactc agaaatgcga aaaaatcggc agaagtccaa aatgcgatca
    45601 tcgagaaact tgtggatctc tatgaagcgg aaggaatcaa tgaagtaaat gaactaaata
    45661 tccaagaaga cggactaaca gttattttgt ttgtcggtgt taatggtgta gggaaaacaa
    45721 caagtattgg taaacttgcc catcagttca aaaacgaagg taaaaaagta ttgatggcag
    45781 cagcagatac cttccgcgct ggagcaatcg accagttagt tgtctggggc gaacgcgctg
    45841 gtgttgaagt tgttcgtggc aatgcaggag gcgatccagc agctgtcgta ttcgatgctt
    45901 tggaaagagc aaagacagag caggcagatg ttttactagt tgatactgca ggccgactgc
    45961 aaaataaagt gaacttgatg aacgaattag aaaaaataaa acgagtaatc cagcgggaat
    46021 taccagaagc accccaagaa acacttcttg tattagatgc aaccactggt caaaacgcga
    46081 tggttcaagc aaaacaattc aaagaaacaa cagatgtgac cggtcttgtt ttgacaaaat
    46141 tagatggtac agcaaagggc ggtatcgtac ttgctatccg taatgaattg catttaccag
    46201 tgaaattggt cggtcttggt gaaggaatcg atgacttgga gccgtttgat ccaaatgatt
    46261 ttgtcgttgg attgttcaaa ggattactaa aagaagaata acccatgtct aaaaagcagg
    46321 agctgtgaca aaagttgcag ctccttgttt gaatgattgt ttttaacata gctgtgtttt
    46381 tgatgccttc atttttatac ttatttgtaa gcggttctca aacaatttcg ttctttttct
    46441 tagacttttt gattataatt agattcatat gaattggagg tcacttaatg atgaatttta
    46501 agcaattatt attgcatgtc aatgcgcgcc cttttatcga ccaagctcga tttggtatag
    46561 aacgggaagg acagcgggtt gatcttgcag gaaatctagc aaaaaccgat catccagcaa
    46621 tctttggcga tcgatcctat cacccctata tccaaacaga ttttagcgaa acacaaacag
    46681 agatgatcac ccctgttacc gattctattc ccgaattatt tcagtatctc gctgctgttt
    46741 atgatgtgac tgctcgttct ataccgaaag aagagatgat ctggccatta agtatgccac
    46801 ctgccttacc ggaaaaagac gaagagatca ttattgcaaa attaaaaaat ttcgaagatg
    46861 tcttgtatcg acgttattta gcaaaagaat acgggaagcg aaaacagatg gtaagcggta
    46921 ttcatttcaa ttttgaattt ggcgatgagt tgctaagaac attgttcagc catcaggaag
    46981 aatttcaaga tttttccgaa ttcaaaacag aactttattt gaaaacagcg agaaacttta
    47041 tgcgctatcg ctggatgatc acttatttat tcggtgcttc accaatgagt gagaagaact
    47101 actttttaga tgaatcacat ccgcaagaac ctgttcgcag tattcgcaac agtgcgctgg
    47161 gctatacgaa tcatccaaat gtgaaagttt cctatgcttc tatgaaacag tatttagcag
    47221 atatcgagcg aatgatcgaa gaagggaaac tttcggagga gaaagaattt tatacaccgc
    47281 ttcgtttccg aggcggaaag aaagtcgcag atttagcaac aacaggtgtt cgttatattg
    47341 aattgcggaa tatcgatttg aatccttatg caagattggg tatcaatcca gagcaagttc
    47401 ggttcttaca attattcctg atgtacatgt tatggacaga agaaaaagaa gactgtgacc
    47461 aatgggtagc agaaggtacg actcgaaata acaaagtagc actagaacaa ccatcagatc
    47521 aaacagaatt tcatcaagaa ggtagagaaa ttcttgaagg aatgaagcaa atgctggttg
    47581 aattggattg gttggattct ctttatttag tagaggaagc attgactcaa atggatcatc
    47641 ctgaacaaac gttagcagcg aaactctatc aagaagcaca gctatcgagt cagcaagaag
    47701 ttgctgtggc attgggacat caatattata aagaaagcca tgaacgtccc tatcagttgg
    47761 ccggttttcg cgaaatggaa ctttctactc agatatttat gttcgatgcc atccaaaaag
    47821 gtgtccaagt caaagtatta gatgagtcgg atcaattttt gcgtctgcaa ttccaagacc
    47881 atgtagaata tgtgaaaaat gcaaacatga caagtaagga cagctatatc gtcccactta
    47941 tcatggaaaa caaaacagta acgaaaaaag tcttaaaaga agctgggttc cgggtaccag
    48001 gaggcgcaga attttcatcc atggaagaag cggtaaaagc ttatccgaga tttgccgagc
    48061 aggcatttgt gatcaaacct aaatcaacca attacgggtt aggtatcacg attttcaagg
    48121 aaggagctag tctggaagat tatcaagcag gtttagccat tgcttttcgt gaagacagtt
    48181 cggttttagt agaagaattt atgccgggaa cggaatatcg tttctttgtg atcgacggag
    48241 aagtccaagc catcatgttg cgagtccctg ctaatgttat tggtgacagt atccgaacag
    48301 tgaaagaact tgttgaagaa aaaaatagtg accctttgcg tggaacgaat catcgtgcac
    48361 ctttagaatt gatccaatta ggtgaattag aacaattgat gttgaaagaa caagggttga
    48421 cgatcgaatc agttccccaa gccaatcaaa ttgtttatct aagggagaac tcaaatatca
    48481 gtacaggtgg tgattcgatc gatatgactg atgaattttc tgaagcttac aaaaaaatcg
    48541 ccgtttctgc ggtagaagca ctaggagcta agattagtgg tatcgatttg attataccag
    48601 ataaagaaat cgatcctaca actgataaaa aagcatatgg gatcatcgaa gcaaatttca
    48661 atccagccat gcatatgcat gtttatcctt ttgcaggaaa aggcagaaga ttgacgatga
    48721 atgtattgaa attgttatat cctgaagtat tttaaaagaa aaagcttttg acagattgtc
    48781 ctatttgatg tcaatctgat caaaagcttt ttttgcatgt aaaaatttat gtgttttttc
    48841 gttttaaaat aaacgatccc agaagctttt tttctttttt ggtttttctt tttcagctgg
    48901 cgaagagttt tcttctgggt attttttttc gatatcaatc acaggttcat ttactgcttc
    48961 ttttgctgtt aagagcaatc cgaattcctc aggatttgca gtgacgtaat cgttgactac
    49021 agtgaaacgg ctattgtttt tcgttgctag ctggatatat tggttttgga cagaaagggg
    49081 tagagcccca ttcaagagta tggaagcatc tggatgtttt ttgagttctt ttaaaaagtt
    49141 ttctttgttt tttggttgga tcatttcagc aacagtcata ctaagatagc agcgttccct
    49201 gaatgtccct aaatatttat gctgttcttc agggttcact aaaggtgtac cataaagtcc
    49261 cttatccaaa tggcttttta catcatcttg tgccataaaa aataccctcc ttcttctctt
    49321 tgtctttctt acgattatag catattccca ataataccta aaacatatga aaaagcggtt
    49381 gcttttgttc aacgattcac ttaaaataag aatgaaaatc attctcaatt agaaaggtgg
    49441 attggatgcg ctacggacga ctagtagcat tattagttat tttaagtagt atttcattgt
    49501 tcatcggagt atcgaatgta caattgtcag aactgctcca gttagatggg caaagcttac
    49561 aaatcttgct agtgactcgt ttgccacgaa cgatttgttt gatccttgtg ggagcgacca
    49621 gtagtatttg tgggttgatc atgcaacatt tgacccaaaa taaatttgtt tcaccaacga
    49681 ctgcgggcac gatggatagt gcgcgtttag gtattttagt ggctatgatt ttcctacctg
    49741 gtgcatcctt gattgtccga tccttgacag cattttgctt tgcttttgca ggaacattgc
    49801 tttttttatc ccttacgcga ttgttcctcc agaaaaatca attgatgctt ccgttgattg
    49861 gagtcatgtt agggaatatc attggttcag ttgctacttt ttttgcttat caattccagt
    49921 tggtacaaaa tatgacttca tggcttcaag ggaattttgc gactgtgata cgaggaaatt
    49981 atgagttatt gtatgctgtt gttccattgt tgctcttggt ttggctattt gcttaccgat
    50041 ttacgatcat tggtctgggc gaatcgtttg cagtaaatct gggaatagat taccagaaga
    50101 tgcagttttt aggcattggc ttagtatcat tggctagtgc agtcatgttg atcatggtag
    50161 gaagcattcc ttttatcgga gtgatcattc cgaatcttgt ctctagaata tatggagatc
    50221 aagtgcacaa aacaattggc gtaactgctt tagcaggtag tttgttctta gtattttgcg
    50281 atcttgtcgc tcgcgtgttg atttttcctt atgaaatacc agtcagtgtg atcgttggaa
    50341 tcatcggtgg ggctatcttc ctttatcttc tgataagggg acgacgatat gcttaaaaaa
    50401 aagccatcta tttttattgg tatgcttgtt cttgttttat ttgttacagg aatgtacttg
    50461 acgatccata catatggaaa ctggcatttt gcatgtgcat tgaggagtaa gaaaattttt
    50521 gcatttatcc ttgtctcgct agctgtcagc agtgccacaa tcagctttca gacaattacg
    50581 cataaccagt ttttgactcc ttcagtattg ggacttgagt cgttatatgt ccttgtccaa
    50641 acggtccttt tcttctttat cggaggagtg acgatgcttc agcagacagg tacagttttt
    50701 ttcttattga acgttgggct gatggtcggg ctgagtctat tgttattttt ctttcttttg
    50761 aaaaaaatga gagcgaatct ttttttatta ctgatgtcag ggatgatttt aggtacgctt
    50821 tttggtagtg tcagtacctt tttacaagtc atcatggatc cgaatgaata tgatttgctt
    50881 caaggcagat tatttgcaag ctttggcaat atccagagtc agtatctttt gcctgcttct
    50941 ttgatcatta tcggctgctg gtacctgtta tttcgatatc gacatgtgct agacgttttc
    51001 catctcggaa atgaacaagc agtaaacctc gggatagaca cagatcgttt tgaatttttg
    51061 attttatgtt gtgtcagtct tttgacaggg acatcaacgg ctcttgtggg tccagttact
    51121 tttttagggt ttattgtcgc aaatatcagt tatcgtgtct tttctactta tcgtcatggt
    51181 cagctattta tcggaagctt tctggtagct atgctgtttc tgacaggagg acagctcgca
    51241 gtagagcaga ttttcggctg gaatacaaca gtgagtgtcg tcgttgaatt tgtcggagga
    51301 atttattttg tcacaaaatt gattcgcgaa aggaagagta tcctatgatt gatttacaaa
    51361 aggtcaataa actgtaccat ggaaaatcag tggttaaaga tgtacagtta acgattcctg
    51421 aaaagaagtt gactgctttt atcggtccaa atggtgctgg aaagtcaacg gtgttgtcga
    51481 tgatcagtcg tttgatacca aaagatacag gtgaaatcta tttagaccat aacgaagtaa
    51541 aggcttggaa atccaatgaa ttagccaaaa aattatcgat cctacgacaa tcgaatgaaa
    51601 taaatgtcca aatcaccgtg aaagaattag tagaatttgg acgatttcct tatacgaaag
    51661 gaaaattgac gacaaaagac gaggaaatcg ttcaggaatc actggaacac attgggttag
    51721 aagaaatagc ggatcaatcg attgacactc tttcaggcgg tcaactccaa cgtgcgtata
    51781 ttgcaatggt gctagcgcaa gacacggatt atattttact ggatgaacct ttgaacaatc
    51841 tagatatgaa ttttgcggtt caaatcatgc agattttaaa aaatttagta caagaaatcg
    51901 ggaaaacaat tgttattgtt cttcatgata tcaactttgc tgcaagttat gcagacgaaa
    51961 ttgttgcaat gaaagatgga cagttattta cgcaaggaac gacccaagaa atgataaaaa
    52021 aagatgtatt ggatgaatta tacgaaatgg acatacggat ttgtgagatt gaaggccgca
    52081 gattctgtct ttatttctaa aactaacatt aggagagaag agatgaaaaa attagtagta
    52141 ggtatcttga ttctagcatc atttggttta gcagcatgtg gaaatagcaa caacaccagt
    52201 caggcagaca caaaaaaaag cagcacacaa actgaaacta cattgacgat aacagatagt
    52261 aatggagacc aaatcgaggt gccaaataat ccagaaaaag tcgtcgtatt cgacaatggt
    52321 tctttagata cgatggatgc tcttggtgtt ggagataagg tagttggagc agctacaagc
    52381 agccttcctg agtatctttc atcctataaa aaagtagaat cagcaggtgg aataaaagaa
    52441 ccagacttag aaaaaattaa tcagcttcag ccagatctaa tcatcatttc tggccgacaa
    52501 agagattttc aaaaagatct aagtcaaatt gctccgacca ttttcctttc tttagatgcg
    52561 aaaaatccat gggaatcttt ccagcaaaat gtcactgctt taggggagat ctttggtaag
    52621 caagaagaag ctaaaactca attagaggaa ttatctagtg caatcgatca gacgaaaaag
    52681 aaagcagaag ctactgacaa aaaagcacta gtcacacttg tgaatgaagg gcaattatca
    52741 gcctacggat ctggttctag attcggtttc atccatgatt tatttggctt tgaacaagca
    52801 gatgatcaaa tcgaagcatc cactcacggt caaagtgttt cttatgaata tgtgctggaa
    52861 aaaaatccgg atatcttatt tgtagtagac agaacaaaag ctattggtgg agacgacagc
    52921 aaagatgata tttctgccaa tgaactggta gcacaaacga atgctggtaa aaatcagcag
    52981 atcatctccc ttgaaccaga tgtctggtat ttaagcgggg gcggtttaga atcaatgaaa
    53041 ctgatgatcg aagatgtgaa tcaagcattt aaatagcata aataacagag gattaaactc
    53101 tcatactatg taacaataat gtttcttaca ttcttaaata gcaagagcct atcctcaaag
    53161 aagttatcaa aaaccatccg taaaatcgta ttgatgattt tacggatggt ttttatttat
    53221 ttgagaaatc ttttttcaac gtgaattcat tatctacatc atacgggttg attctagaat
    53281 ggggagtggc aaaaaatagt gtgatccatt ttttcagcat caagatcgcc tcctttgatt
    53341 tgaatcaaag gtacaaagcg aaacttagat aaaacttaaa tttagatatt tttattttgt
    53401 accgatctct tctttaaacg atgttccatc tgctgcttct cggcaataag tccactagac
    53461 tagaaaatat gagaagctat tttctgtcca gcgttcttat tactcaaaac aaatcgcagt
    53521 tgtcacaatc tcttctaaac gatgttccat ctgctgcttc tcggcaataa gcccactaga
    53581 ctagaaaata tgagaagcta ttttctgtcc agcgttctta ttactcaaag caaatcgcag
    53641 ttgtcacaat ctcttctaaa caatgttcaa tcagctgacc ttcggtatta gctcaaagca
    53701 ctgatttcac aacctctatt taggcatgtg tctcagcaag cggttgatag ttgatgatct
    53761 gcatttttcg ataaaaatcg gcgggaagct tactccaccg ttttagtaat tgatagaaat
    53821 aactctcttc tgctttgatt ttatactcgc ttaatatcaa tccaaaacta ttcgtttttt
    53881 ttgaagctaa ttttttataa atatccaatg ctttggtttt atcttcattg acaaagagtg
    53941 tttttacttc aatataagaa ccctcgatat tttgtgtttc ttcgataaaa tagatgtttt
    54001 ttatatattc cttcatagtg attcctccaa agaagtcttt tatttgataa gtttactcta
    54061 ccgaagagtt gttaataatc cgtgaacaaa aagtaattct ttttccaata gttgttaaag
    54121 gttttttatt ttttatagta ttttttgtta tttaagaaag gaataaggtt aaacaaataa
    54181 caggttgctt tttgggtctt tttccgttca agaaactgaa cgaagaaaag ggaaagttgt
    54241 ctcttttgtg ataagagaaa tcataataaa cgaatgactt actttccaat aaattgagaa
    54301 cagtcagaac cagacaaatt agttgcatct gatgaataaa gtgattattc tatgacatga
    54361 ggtgatacag atgaaattag aagtgacaaa agaagcacaa gaagtattga agaataaatt
    54421 agaagcagac gatcaacttt tattagatat cgaaaacggt gacggtccat ttgcagaaag
    54481 ccaagtcagt tgccaattgg atacggcatt tcgattgatc attgtcaaaa aagatacaca
    54541 aacagatcta agtctttatt ctgtagtggc tgatacacca gttggaccaa tcaaaatcaa
    54601 agacagtgca atactttaca tggatgatcc atccacactt gctttagaac caacttataa
    54661 tagtttacaa ttaaaaggac caagcggctt gagaaaaggc aacttgcaag ttgttcgaaa
    54721 agactagagg gataaaatgg gaaaattggc gatcatcagc gacctacatg tggacatcaa
    54781 taaattcggc gaatcagagc tgatgcagct ttggcaagtt ttgcaaaagc acaagatcac
    54841 tcggcttcat ctagccggag atacggctaa taaagtagac cgttgcctag ctgttgtcga
    54901 atttttcgtc aataaaggat tatctacgac atttcatttc ggcaatcacg agttggcaga
    54961 tgtgcccaat gaacagatga tggaccattt tccagaccca cattttttaa atgaacggta
    55021 tattgcttta aatgagcaga ccgttctttt agggatgaat ggctggtacg actatcagtt
    55081 ttccgaattg aaagattacg aggcaatcgt acgaatgaag cgtttgtatt ggtatgatcg
    55141 gttcatccag cgtgggaaaa cagatctcga ggtcaatgca gaaatgcttg cagctgcaaa
    55201 aaatttgcta gaccagctgg aagcaaaaaa acttgaggtg attttatcca ctcatttcgt
    55261 tcctaaacgg gcatttatca tgtatcaatc tgctccttat gagcgttgga acaaattaaa
    55321 tgcattttta ggatcagaat cattcggaga attacttgac cgttattcaa atatcaaaca
    55381 agtagttttt ggccatacgc atcgtcgctt tgaagataaa tccatcggtc acacgattta
    55441 cagctgcaga ccttttggtt attattatga atggcagctg acccgagatt ttgtcttgaa
    55501 agaacagttg ctagacagct atgatcctat gaaattacgt gtcctcttgc gtgcccatca
    55561 cccagctttt caggcctatc aaacacaaca tttgcaagag gaatttgaac aagcgatgac
    55621 aatcgttccg tattgagaca gcattagtaa tgtgtaaaag aaaatacctt gtaaaacata
    55681 aggataagta agagcagtag atccatttat cgtggatatg ctgctttttt tgcggaaaat
    55741 aatcagcgaa tgtttatttg atcggatgat ttgtaactcg cagagtacta gatgcaagcg
    55801 tgtattcttt ttttgaacga taatcacaaa aaaaaatata atatacattt tttatttaat
    55861 tataattaat attgattgaa gtctaggcag tcaagtcgag agtgtaaaat attttgtgta
    55921 aatgaaaaaa tccatacaaa aaaggaagtc
//
LOCUS       DAPBBV010000016        55270 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.016, whole genome shotgun sequence.
ACCESSION   DAPBBV010000016 DAPBBV010000000
VERSION     DAPBBV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.016"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(148..2301)
                     /locus_tag="RD486_001179"
     CDS             complement(148..2301)
                     /locus_tag="RD486_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDT7662922.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2595..3443)
                     /locus_tag="RD486_001180"
     CDS             complement(2595..3443)
                     /locus_tag="RD486_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7662923.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="RD486_001181"
     CDS             complement(3667..5607)
                     /gene="thrS"
                     /locus_tag="RD486_001181"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDT7662924.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5944..6123)
                     /locus_tag="RD486_001182"
     CDS             complement(5944..6123)
                     /locus_tag="RD486_001182"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HDT7662925.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6170..7993)
                     /gene="cadA"
                     /locus_tag="RD486_001183"
     CDS             complement(6170..7993)
                     /gene="cadA"
                     /locus_tag="RD486_001183"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDT7662926.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8271..10550
                     /locus_tag="RD486_001184"
     CDS             8271..10550
                     /locus_tag="RD486_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7662927.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10643..11290)
                     /locus_tag="RD486_001185"
     CDS             complement(10643..11290)
                     /locus_tag="RD486_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7662928.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11469..12188)
                     /locus_tag="RD486_001186"
     CDS             complement(11469..12188)
                     /locus_tag="RD486_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7662929.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12319..13470)
                     /locus_tag="RD486_001187"
     CDS             complement(12319..13470)
                     /locus_tag="RD486_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDT7662930.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13687..14427)
                     /locus_tag="RD486_001188"
     CDS             complement(13687..14427)
                     /locus_tag="RD486_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7662931.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="RD486_001189"
     CDS             complement(14431..14754)
                     /gene="rsfS"
                     /locus_tag="RD486_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDT7662932.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14811..15404)
                     /gene="yqeK"
                     /locus_tag="RD486_001190"
     CDS             complement(14811..15404)
                     /gene="yqeK"
                     /locus_tag="RD486_001190"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDT7662933.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15388..16038)
                     /locus_tag="RD486_001191"
     CDS             complement(15388..16038)
                     /locus_tag="RD486_001191"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDT7662934.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="RD486_001192"
     CDS             complement(16048..16359)
                     /gene="yhbY"
                     /locus_tag="RD486_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDT7662935.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="RD486_001193"
     CDS             complement(16375..17484)
                     /gene="yqeH"
                     /locus_tag="RD486_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HDT7662936.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17481..18008)
                     /locus_tag="RD486_001194"
     CDS             complement(17481..18008)
                     /locus_tag="RD486_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HDT7662937.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18188..18973)
                     /locus_tag="RD486_001195"
     CDS             complement(18188..18973)
                     /locus_tag="RD486_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HDT7662938.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18966..19835)
                     /locus_tag="RD486_001196"
     CDS             complement(18966..19835)
                     /locus_tag="RD486_001196"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDT7662939.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19836..21215)
                     /locus_tag="RD486_001197"
     CDS             complement(19836..21215)
                     /locus_tag="RD486_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDT7662940.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="RD486_001198"
     CDS             complement(21223..21642)
                     /gene="fabZ"
                     /locus_tag="RD486_001198"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDT7662941.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21667..22143)
                     /gene="accB"
                     /locus_tag="RD486_001199"
     CDS             complement(21667..22143)
                     /gene="accB"
                     /locus_tag="RD486_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDT7662942.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="RD486_001200"
     CDS             complement(22146..23381)
                     /gene="fabF"
                     /locus_tag="RD486_001200"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDT7662943.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="RD486_001201"
     CDS             complement(23400..24137)
                     /gene="fabG"
                     /locus_tag="RD486_001201"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDT7662944.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="RD486_001202"
     CDS             complement(24149..25066)
                     /gene="fabD"
                     /locus_tag="RD486_001202"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDT7662945.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25173..25397)
                     /locus_tag="RD486_001203"
     CDS             complement(25173..25397)
                     /locus_tag="RD486_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDT7662946.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25450..26412)
                     /locus_tag="RD486_001204"
     CDS             complement(25450..26412)
                     /locus_tag="RD486_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDT7662947.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26422..26862)
                     /locus_tag="RD486_001205"
     CDS             complement(26422..26862)
                     /locus_tag="RD486_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7662948.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27168..28133
                     /locus_tag="RD486_001206"
     CDS             27168..28133
                     /locus_tag="RD486_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDT7662949.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28190..28420)
                     /locus_tag="RD486_001207"
     CDS             complement(28190..28420)
                     /locus_tag="RD486_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HDT7662950.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28506..29393)
                     /locus_tag="RD486_001208"
     CDS             complement(28506..29393)
                     /locus_tag="RD486_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDT7662951.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29482..30705)
                     /locus_tag="RD486_001209"
     CDS             complement(29482..30705)
                     /locus_tag="RD486_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7662952.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIRKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30722..31768)
                     /locus_tag="RD486_001210"
     CDS             complement(30722..31768)
                     /locus_tag="RD486_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7662953.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31932..33659)
                     /gene="ptsP"
                     /locus_tag="RD486_001211"
     CDS             complement(31932..33659)
                     /gene="ptsP"
                     /locus_tag="RD486_001211"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDT7662954.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33659..33925)
                     /locus_tag="RD486_001212"
     CDS             complement(33659..33925)
                     /locus_tag="RD486_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HDT7662955.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34404..36638
                     /locus_tag="RD486_001213"
     CDS             34404..36638
                     /locus_tag="RD486_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7662956.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36786..37106
                     /locus_tag="RD486_001214"
     CDS             36786..37106
                     /locus_tag="RD486_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDT7662957.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37311..37535)
                     /locus_tag="RD486_001215"
     CDS             complement(37311..37535)
                     /locus_tag="RD486_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HDT7662958.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37733..39313)
                     /locus_tag="RD486_001216"
     CDS             complement(37733..39313)
                     /locus_tag="RD486_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDT7662959.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39714..41090)
                     /locus_tag="RD486_001217"
     CDS             complement(39714..41090)
                     /locus_tag="RD486_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDT7662960.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41218..42336)
                     /locus_tag="RD486_001218"
     CDS             complement(41218..42336)
                     /locus_tag="RD486_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7662961.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42478..42912
                     /locus_tag="RD486_001219"
     CDS             42478..42912
                     /locus_tag="RD486_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7662962.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(42990..43523)
                     /locus_tag="RD486_001220"
     CDS             complement(42990..43523)
                     /locus_tag="RD486_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HDT7662963.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43617..44795)
                     /gene="mutY"
                     /locus_tag="RD486_001221"
     CDS             complement(43617..44795)
                     /gene="mutY"
                     /locus_tag="RD486_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDT7662964.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44788..45585)
                     /gene="recX"
                     /locus_tag="RD486_001222"
     CDS             complement(44788..45585)
                     /gene="recX"
                     /locus_tag="RD486_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDT7662965.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45692..47074
                     /gene="rlmD"
                     /locus_tag="RD486_001223"
     CDS             45692..47074
                     /gene="rlmD"
                     /locus_tag="RD486_001223"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDT7662966.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47248..47826)
                     /locus_tag="RD486_001224"
     CDS             complement(47248..47826)
                     /locus_tag="RD486_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HDT7662967.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48148..48618
                     /locus_tag="RD486_001225"
     CDS             48148..48618
                     /locus_tag="RD486_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDT7662968.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48726..49952)
                     /locus_tag="RD486_001226"
     CDS             complement(48726..49952)
                     /locus_tag="RD486_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7662969.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKFLKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(50706..50906)
                     /locus_tag="RD486_001227"
     CDS             complement(50706..50906)
                     /locus_tag="RD486_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7662970.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(51040..51648)
                     /locus_tag="RD486_001228"
     CDS             complement(51040..51648)
                     /locus_tag="RD486_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDT7662971.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(51733..52203)
                     /locus_tag="RD486_001229"
     CDS             complement(51733..52203)
                     /locus_tag="RD486_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDT7662972.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(52251..53165)
                     /locus_tag="RD486_001230"
     CDS             complement(52251..53165)
                     /locus_tag="RD486_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7662973.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            53311..54114
                     /locus_tag="RD486_001231"
     CDS             53311..54114
                     /locus_tag="RD486_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HDT7662974.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            54292..55239
                     /locus_tag="RD486_001232"
     CDS             54292..55239
                     /locus_tag="RD486_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDT7662975.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT        15898 a        11667 c         9443 g        18262 t
ORIGIN      
        1 ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa agccagtttc tcggtatgaa
       61 gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa atttttcttc atactcgaaa
      121 ctaagcggct ttttcacgac ctctttttta ttttgccatg aacatatcat aatacgcgtc
      181 cattatttct ttagcaatcg tcaagtttat gtggtcttgt tcgtctaata agttcggcaa
      241 gacaacactg atggcaattt ccggattgtc tgttggtccg tatgccacga tattactatt
      301 gactgtcgca atatctggat gaccttccgc aaccgtttct gcagtccctg tttttgcgga
      361 aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg taaggatcgg taccatggac
      421 aacttggtgg aatccttcac ggaggatcgc catattttct gcagaaatat tgaccgtatt
      481 ttctactgtt gtgccaattt ctttcttcac ttcacccaag tttccatttt cgtcattgcc
      541 atagatcgct ttgactaggt gcggctgtac tcgtttcccg ccattagcga ctgttgaagc
      601 atattgagct aattggattg gtgtatatgt gtcaaactgt ccaaatgcca aatcggtaaa
      661 gttacctgga gcataccatt ctttgccatt atccgcattg aacttcttca tataatcaac
      721 agaacgtgag atcccaggag attcattcgg caaatcgatc ccagtcgttg taccaagacc
      781 aaactctttg aaagagtctc tcaattgctg ataagcttta gcttcttcat ctaaactagg
      841 tagtcccatt ccaggtgtat agtctagtcc taacatcttt aacgccactt tgatcatata
      901 cgtattagaa gacaattccg atgctttgac tgcatcaaga gcaacttgtc cgcttcgatt
      961 aaagacagag cttttttctg aagcaccttg cagacgaatc ggctcatcaa tcaaaacttg
     1021 atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa gtaccagcct tgactacaga
     1081 ccctggatca aaggcgctag taatcgtgcc taaagcattc tcggtgattt ctttggaacc
     1141 ttgttcatga ctgaaaccag tcattgctag cacttctcct gtctgaggat tcatagccac
     1201 tgcataagca ccaggcgaat actgtgcttt gccgttgttg atcaatgttt gataattcct
     1261 tttcaaaatt tcttctactt ttgattggaa ttctgcattc atagataaca ttaaattaga
     1321 acctttttcc ccagagaaga tttctttttg attcgaaaca tttccttcat tatcaaggga
     1381 aacttcatat tgggttttgg ttccttgcag gacatcttca tattgttttt ccaaataact
     1441 ttgtcctaca cggtcattcc gagaataacc ttttgctagg tatttctctg cttcatctgc
     1501 tggaagtcct tgcttttcag tcgtcacact gccaagaata cttttcagtg aacttgctgc
     1561 attatattct cgtgtccagt ctgtgccagt cgaaactcct ggaagttcag aagcgcgttc
     1621 tgccacaaca gctaactctt gatcagtaac accagagttt ttgatataga cagtgtttaa
     1681 ttcatatgca ctattcatcc gtttaaagat ggtagcaatt tttaattgct cctcgtttaa
     1741 attaatctca tcagctgtga ctttattgac catcgcacta tattgttcgc tgttccctaa
     1801 ttgcttttct tttgccgaaa gtctttttgt ggcttctttc aaatgtttgg gatcagccag
     1861 ccaaaaatct tttttatctc tatctgtcag attttcatct accggaacat cgatcagcga
     1921 gttcagcttc gttgcgattt caagcaaatc tttagccgta acttgtgttc ctctcgtata
     1981 tgtgatggcc tgattcgctt tattcgtaac taaagctttt cctgtggagt cgtagatcat
     2041 tccgcgagga gtactttctt ggaccgtaat cgtagaagta gacttcactc gcgcctccat
     2101 ctcttcgccg ttcacgatct gcaaataacc caatctagca atcaacgcaa caaataacgt
     2161 aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca tgggaccggc gaaacgtttt
     2221 gttcttaggt tcttgtgcac cttttcttat tttttctaac caagaagtat ttaatatttt
     2281 tttcataaaa tctttcatca tttcctatcc ttccgcctat ttacattcat gcttcattgt
     2341 acccaaaaac ttcttaataa aaaagaaaaa atgggcggag caagaaattc tttacctaat
     2401 ttcaagataa aatcaacttt ttgtttcaca gcaatcactt aaagttacat atccaactat
     2461 ttttttcatt aaaaaataaa cttatttttg aaaattatgt tttcttaagt cgtgaaacac
     2521 tttgatggat catttatttg tggaaaacta cgttttgtta ttctaaaaaa cttatataaa
     2581 aaatagtaag gtttttattt cgaatccata aaatattctt ggattgcttc tcgtgttttt
     2641 ttcacttttt cgctaagctt ttcgttttta gccatataga aataaaaaat gatatcgatc
     2701 gtagcaaatt gggccaaaag tgaattagtt gccgcacttc gattcgtgat ttcttttggt
     2761 ctagatgttt gtacgagtac atcggctatc ttgctaagcg ggttatttcc aaattgcgtc
     2821 aacgcaatga tttcgatatt catgcttttc gccagctcgg ctaatgcgac tacatctgca
     2881 cttctacctg agtttgaaac aagccaaagc actttctttt tctcattgct gacaagttgc
     2941 gggagcaaga cgtggatatc tttttcaaaa atgattggct taccgacacg agaccatttt
     3001 tgcagaatat cttctactac taaagaagag gcgccaaccc catataaaaa aacagtctct
     3061 gccgattcca aacactctac gactttttgg atcgtttctt cttctagaat atctactgtt
     3121 tcttttatcg ctacttgtgc attgttacca agtttgtttt tgatagagta aaaggactca
     3181 tttgcttcta tatcactaaa accttcatcg attccagtct gtagttctgt tgaaatcgtg
     3241 attttgaagt ccgtcagact ttgaaaaccg atttttttgg aaaaacgtac aactgtcggc
     3301 gcactcaacc cggaagcttc tgctaattca ttagctgtca ttgtagggac cttctcaata
     3361 ttaccgataa tgtagttggc caactttttt tctgctgaag aataatcttc catcatactt
     3421 tcaatacgac taattacgct cataagttcc tccacccttt taatgatagt ctatgtaagt
     3481 ataccatatc agacccttat tcacggtcgt atactggata aaaaacaaaa aaacaatccg
     3541 cccaacagaa tatcttatcc catcaatccc acagattcta ttgagcatct gtgtctttga
     3601 ggaatacctg ttatctattg ttcggattgc tttctatcta ctactttttt acaggaaatt
     3661 tacctattag ttttctctgc tgtaattttt gacttctgct tccatagcat caataaagat
     3721 attcaaatct tctacagctg tttctttact tccataacga cgtacgttca ctgttgcatc
     3781 ttccaattcc ttgtctccaa caactaattg gtaagggatc ttttgtgttt gagaggcacg
     3841 tatcttatag cccatttttt cattacgatc atcaacttct acacgcaacc ccttcatttg
     3901 caaacgttct ttgatttcat aagcataatc gccatgtgca tcaacagaaa cagggatgat
     3961 tgttgcttgt ataggtgcca accatgttgg aaaagcgcct ttgtatactt ctgttaaata
     4021 agcgacaaaa cgttccattg tagaaacaat tccgcggtgg ataactactg gacgatgcgt
     4081 attttccccg tcttctccaa catatgtcaa atcaaagcgc tctggcaata agaagtctaa
     4141 ttgtatagtt gataatgttt cttctgtacc aagagctgtt ttgacttgaa catctagttt
     4201 tggtccgtaa aaggctgcct cgccttctgc ttcaaagtaa tctagttcta attcatccat
     4261 agcggctttc agcattgctt gggctttttc ccacattgcg tcatcatcaa aatatttatc
     4321 tgtattgttt ggatcgcgat agctcaagcg gaaacgataa tctgtaatat tgaagtcagc
     4381 atatactgcc accatcaatt caagcgtacg tttaaattca tctttgattt gatcaggacg
     4441 aacaaatgta tgaccatcat tcaacgtcat ttctcgtaca cgttgtaaac ctgacaaagc
     4501 acctgatttt tcatagcgat gcatcattcc taattcagcg atacgaattg gtaattcacg
     4561 ataagaatgg atcgtgtttt tgtagaccat catgtgatga gggcagttca ttgggcgaag
     4621 aacaagcatt tcgccatctc ccatatccat tggcgggaac atgtcttctt gataatgatc
     4681 ccagtgtcca gatgttttgt acaactcaac atctcccatt attggtgtat atacatgttg
     4741 gtaacctaga ctaacttctt tgtctacgat ataacgttcg atcgtgcgtc ggattgttgc
     4801 cccttttgga agccagaatg gcaaaccaga acctacttct ggggaaacca tgaacaagtc
     4861 aagttctttt cctagtttac gatggtctct ttcttttgct tcttcacgga gacggatata
     4921 ttctttcaaa gctttcttgt caaaaaaggc tgtcccgtat acacgttgca tcatttgatt
     4981 gtttgagttt ccacgccaat aagcacctgc cactgataat aatttaaata cttgtatacg
     5041 gccagtggat ggaacatgtg gtccacgaca caaatcgatg aattcgcctt gttgataagc
     5101 agtaatcact tcttcttctg gcaattcact aatcagttct actttgtacg gatcacttgc
     5161 aaaaatttct aatgcttcct gttttgaaag aacacggcgt tcgatcggca gattttcttt
     5221 gacgattttc atcatttctg cttcgattgc cggcaaatct tctgcagtta cttggttttg
     5281 tccattatct gtatcgtagt aaaaccctga atcgatagct ggtccaacgc caaagtggat
     5341 atttggatag aggcgacgca tggcttgggc catcaaatga gctgctgaat gacggactaa
     5401 gccaagtgca tcttcatggt ctggtgtgat gatctcaata cttgcatctt cctcgattgg
     5461 acgagtcaaa tcaacgagtt ttccgttcac tttaccagct aaagcttttt ttgctaagct
     5521 ttttgaaatg ctttcagcaa ttgccaatgt tgttgttcca gactcaaatt ctttgactgc
     5581 accatctgga aaagtaattt ttatcataat agtttcctcc ttgaaatgtt ttgattgatc
     5641 agatcatcaa gctgaaaaac aaaaaaatcc tagcatctct tgaaaagaga tactaggacg
     5701 aaaagttcgt ggttccacct aatgttcaaa cgcaaatgcg ttcctcaagc gttgtaacgg
     5761 tccgaccgcc cttgcttcaa caagggtttc gaaagtggtc atcctttggt tttctcctgg
     5821 aaaagtttca gcctagcttt tcctctctta tcgaagactc tcaaattcag ttggctttct
     5881 catcaatcaa ttatgtgttt atttaaccac taataaatag aaaaatcaag tgggaaacta
     5941 aacttatttt ttccattccc catttacacc gtatgttcct tttttcatct cattgatgat
     6001 gacatggatg tgttcttttg gtgcctgcgt gtttttatga acagcttccg tgatatcttt
     6061 catcatattt tctaattgtt ccggactgcg accttctact aattcgacat gtacgaatgg
     6121 cataatgctc tctcctcttt ctgatcgttc ttttttcaac tcgattctat catactatgt
     6181 ttgtcttggg tactgaatca ggaaaaatgg ctggatcttt ttttgctctc aaggcactca
     6241 aaatagagac cgtatccacg acttcttgca aaacagctcc gaataatgcg gggattagtc
     6301 ccgtacttgc aattaacatc aaaaaaatac aaataaagat gccaatcagt acagactgtt
     6361 tcgctattct catcgtatct cttgaaatca ctactgcttt tgctacacgc aagagatcat
     6421 ctttcaagat gaccgcatct gcactttcac tagcagctgt agaaccatga gcccccattg
     6481 caataccgat atctgcagca gcaagtgctg gtgcgtcatt cacgccgtct cctaccatcg
     6541 caacaggtct ttgatcttta gggatacttt ctaaaatggt cagtttatct tgaggcaagc
     6601 tacgggcatg tacagaatct aattggactt tttctgcaat cgtttgagca atggcagatc
     6661 catccccggt gatcatcatc aaatttttca catcaagttt tcttagctcc ttgattgtct
     6721 ttgctgcttc tgggcgaatc tgatccgaaa ataggatcgt tcctgcaaaa gatcgatcaa
     6781 ttgttacata gattgctgta ttggacgttt ctatttcttc agctgaaaca aaagaggcac
     6841 gtccaatctt tacttcatga ttattgacta ctgcttggat tccttgaccg gtcacttctt
     6901 tcagttgact aacaggatac agttggctgt ttttcacgtt gttcactaac gaacgagcta
     6961 agatatggct agattcctgt tctgcactag ctgcatacag aagtagctct tcttttttta
     7021 ttccattgac tggctgaatc gcctctactt ccaatatccc tttggtaagc gttcctgttt
     7081 tatcaaaagc aatcgttttt gtacgtgcga gcttttcaat cgttgttcca gtttttacaa
     7141 cgatcccgtt tttacttgaa cggctcattc ctgcaactaa agcaatgggc gcagctagaa
     7201 tcagtggaca aggtgatgcc actaccagta cctcagcaaa tcgtaaaggg tcttttgaga
     7261 accaccaaga aataccaccg atcaaataag caatcaacgt gaaagggact gcataacgat
     7321 cagctaaacg gacaaatcgg gcaggctttt cttttgattc ttcgactagt ttaataatca
     7381 tttgatactg gctgtctgcg gcacgttttt cagcgatcat ttggatcgat ccgtctccat
     7441 ttaaagaccc tgacataatc tgatctccag gtttcttggt ttccgggcgg gactcacctg
     7501 tcaaagaaga ttcatcgacc gaagattctc ctttggtcac tcgaccatct gcgggtacaa
     7561 gttcgccagg cttgactagt aactggtcat caatatttat ttcatcgatt actatatcct
     7621 gcaattttcc ttctttgaat cgatgggcaa ttcttggggt gttatctaac aaagactgca
     7681 gttctttacc cgctcgttta ttcgcgtaat cctctagact atctccgccc gtaagcatga
     7741 tcaatatcat caaactagcc cagtattctt tgacggctaa tgttgcaagg attgcggtaa
     7801 tcgctaatac atctacgcca tatcttcctg aacgtaacgt cttgatcatt tccaaaaaca
     7861 tcaagaaggc gagaatccct ccagtaaatg cgacaatcgc aaatgcaagg gccggctggt
     7921 gaaaaacaaa ttcacttaat aaagctatcc caccaataag caaagtaagt aaaaattttt
     7981 tgaaatgtgt cattgttttt tctcctcttt tatgtgactt agagaggtta gtaataaatt
     8041 tccagctgcc tctttcatct taagcatagt ccttgactag cactttttaa aacaataggc
     8101 cttaattgaa aacaactatc actatcagcg tttccaaaat tcatcagttc tacaaacaaa
     8161 aatattcagc aaggattact ttttcgattc atcagttaaa aagtaccttt tttcgaaaaa
     8221 ctatgctata cttttaattc gttatttacg gcggaaggag caaacatgcg atgaatgaga
     8281 aacaactaga acaaacgcac gtggatgaaa cgatcgaact aatccagatc gaacaaaata
     8341 tgctggatac aaaacaacaa gaattgactc aggaaatgaa tcattcgaca aaagacacag
     8401 ctaatcacaa gattcgagct ggttccaatg aagcttttta tgaatctgct gttgaatatc
     8461 gccaacatga gcaggaattg cttttgaaat accatactct tgaagcacag caaaaacgcc
     8521 tgcaaacgtt gtctgtcatg aaagatagtc cttattttgc ccgtatcgac tttaaagaag
     8581 accgtgaaac agaaacatta tatctaggta tcgcttcttt aagagatctg gcagaagaaa
     8641 caatcgttat tgactggcgc gcaccaattg ccaatcttta ttatgaaggt gagattggtc
     8701 ccgcatttta tgaaactgaa acagatagaa tagatgtcga tctgcagttg aaacgacaat
     8761 ttaaaatcca agaaggacgt attttatcta tggtagatac gtcggaagta atcaatgatg
     8821 actttttgct agagatattg gatgaatcat caagcaacca tatgaaaaac atcgtctcta
     8881 cgatacaaaa agcacaaaat gcaatcattc gggacacaac aagtaaagta atgctgattg
     8941 aaggaatcgc cggaagtgga aagacatccg ctttgcttca acgtattgct tttctgttgt
     9001 atcataatcg caagtggctc gaggctgaaa acgttcttct attttcaccc aaccatttgt
     9061 tttctgatta catctcgact gtattgcctt cattaggtga aagcggcgtg cctacacaga
     9121 cattcaaaaa ttatttggtg cagctgctgc cagagttttc tttactagat gaacagcaac
     9181 aagaaagtgg ttttttgcta ggggaaaaag atccgataca agtgatgaaa agcggattga
     9241 ccttagtcga tcagattgat cgctatatcc aaggcatcac aaactacggt cccttgttcc
     9301 gtgatatgaa aataaatggc cgtacgatcc tatcaaagga atcgattcgc caatggtata
     9361 aagaaacaaa tgaacaatta cctttacatc atagactttc tctattacaa acgaagctcc
     9421 tgaaaaaatt aggcggtctg caaaaagacg aaacacgtca gcaatgggtc aaagatctgg
     9481 cggaagaaca gctccaagaa ctatacgcaa cagatccaaa tcttgaatat acagaacaaa
     9541 aggagcgttc attacgtaaa aaactggcca accaaatcgt acgtaaaaga ttccgtcgaa
     9601 tccatcgagg gatcatgaat tatcaatttg tcaatataac gaaacaatat ctccactttc
     9661 tacaaactgt gccactttct cttctaacac gacataaaat cagcgagacc aggtggcagg
     9721 aacatttgac aactgttcgt acacacttgc gtcaaagaga attgcgtcaa gaggatgctg
     9781 tactattctt tttactgatg cgccgaacat atccagtgac ggttacacac aaagctcgct
     9841 atatctttat tgatgaaatg caggatttcg caccatcaca agtggcattg ctgcaagctt
     9901 tgttcccaaa agcaaatttg actttctgtg gagatctaaa tcaaaatgtc tttggaaatg
     9961 aaacgatcgt tggatcattg gaagaccttt tcgtggaccg tgaagtcact cgtttccaat
    10021 taacgacaag ctatcgctcc acaaaagaaa tcactgattt tgctaatcat tttattgtga
    10081 aagaacatca agtagaaaca acagcaagaa aaggagacct tcctttgctc atccaaggaa
    10141 caacagatga tatcaaattg aattggttag cagataccat tcgaacgact cagggaaaag
    10201 cccggtattg gcgtacagca atcatagcta aaacacaaga agaatgcgaa gctctttatg
    10261 ctcaactgcc agacgagttg aaacaacaag tccagctgat tttaaatgag agtgacttta
    10321 tgaagcgttc cattatttta cttccagcct ttttagcaaa aggtctggag tttgaccgag
    10381 ttttcttgtg ggatgtagat gcagaacatt tttcttctca gcaagacaaa ttgatccttt
    10441 acaccatgtg tacacgtgcg atgcatgaat tgaccctttt tacctccaat aatgaaagtc
    10501 ctttgttaaa caatatggat atttcatctt atgagaaaaa agtactgtaa gtaaaaagac
    10561 aactgctatc attaatgtta gcagttgtct ttttatttac aataataatt gcagaaaaag
    10621 taattcaatc atttaaggtc atttattcta tatataaatc caaatctgtt tcaggatatt
    10681 ttaatttgac aagcgaaata atcattttca gttcttccat gttttctgga tattctgggt
    10741 caaatacctt gctatgacgg ccaatcccgc cattgtcgat caatcggtaa attcgattcc
    10801 attcaatgaa ttggtcaatt gattggaaat tgctgattgg atagccgcca caatccaaaa
    10861 tctctgatac acgaaatgct aggtatgcac tatcgatcac tttatttttt ttcgtgtcta
    10921 tcttctcatt tctttcgata agaatttttt caggacgatg tttcaagctc cactctaata
    10981 gtagaaagaa agcctccatc cgatactctt cttcaaataa ccgaaaggct gaatcagaac
    11041 gacgaaaaag cagcggaatc agataatttt gtctataaat cagcattggt gcgcggtcca
    11101 ccatacactc taaataacgg ttcagatacc ctgtaccgac atagtttcct aatcgatagc
    11161 cttcaacgcc gaatcttgcg tatttttgcg ctaattttga acaatcagtt acgttcacag
    11221 ctaactcttc tactttgcgg taaccgctta agatacgttc aaaaggttct aaagtgattt
    11281 ttgcttccat attcttcccc gtccatcttc cacatacttc atatcatttc acatgatact
    11341 tatgctctca tcataccaca ggttgaatta gaaaagaaaa taaatcacac aaaaaagcaa
    11401 gacaatctgt tagtgagatt gtcttgcttt tcgaaaaaga ctgaatactt ttcgttaaaa
    11461 ctggttgctt agtcttctaa tgccacatta tggaacacat gctgtacatc ttctagatct
    11521 tccagtgcat caatcatttt ttcaaatgtt tcttgatctt ctggagatag tgttacctcg
    11581 ttttgaggga tcatttggat ctcagcgatt gaaaaatcag tgattccttt ttcttttaat
    11641 gcttcttgta tactatggaa atccgctact tcaccgtaaa cgatgatttg tccttcttct
    11701 tccattacat cgcgaacatc gatgtctttt tccattaggt attcaaggat ctcgtcagcg
    11761 tcttctcctg caaaagcaaa gattgctgta ttgtcaaaca tgtaagaaac cgctccggaa
    11821 acacccatgt tcccgccatt tttcccaaat gctgcccgta cgtctgctgc tgttcgattc
    11881 acattgttcg tcaatgtatc aacaatcacc attgagccgc ttggtccaaa tccttcatag
    11941 cgcaattcag agtatgtttc atctcctgca ccttttgctt tttcgattgc tcggtcaata
    12001 atatgttttg gtacattata agttttagcg cgatcaatga cgaaacgtag tttttggttt
    12061 gcatgcggat caggatcacc tgattttgct gccgcgtaga tttcaatccc aaattttgca
    12121 taaatccggc tattattagc atctttagca gttttctttg ctacgatatt tgcccattta
    12181 cgtcccatat tttcacttcg ctttctgatt tgatagtttc ataacgcaaa aacgtcctgt
    12241 tccattatac ttgtgaatca cgattctgtg aagctttttt tctttcttcc ttcattcttc
    12301 tcatttttag tcaattatct atactcggat tgggatttgc ccgaaattct gttccggaat
    12361 attgcctccc aattgataga tttgatcact tctaactaac agttccgctt cttgtgcctc
    12421 tttttttccg attcgggaat aaatagaaat ctcttttttt tcttttaaga atcttcttcc
    12481 agcatcggta aatccaagta gtcgaagata atttttattt tgttggacag gaatctcttg
    12541 ctttttgata ttcagcaaga cataacaaga taatcgttgg atccgtgtcc atgtatatct
    12601 ttttgttttt acctttgaca caaaatcctc aaaactatca gcagttgcag ctgctgtttt
    12661 catgcgcgat tctattcctt cggtcatctg atagatatct gtcagttcca gcaaagtaga
    12721 agataacaac cgataacgca aatacggcca ataagattcc caagtctgca gcgaacaagt
    12781 tgaaagatct tcttctgtct gaggcggcac aagtccagct attctttttc cttcttctaa
    12841 cgcatggcga atggctgttg cactggctat cctctgatct gtgatgattt tttcatgata
    12901 gcctgcactt ttacgtcgga tcggatgtaa ttccataggg tggacatact tggcattttc
    12961 ctttgcataa cttaatccca agatatgatt tggcgaagaa aaatcaagcg taatatcggg
    13021 atacagactg cgaaaaacct cagtcatttt ttgcggataa ctatacgttt gatcagacag
    13081 ttcttgaaat gcctcttcta tcctatcttg attctcttgg acaaagcgtc cgaaactgct
    13141 gtaatcaaac gaagtctctt cttctgttcc aaaacacaaa ctgtcacagt ccagtgtttg
    13201 caagattttt actgcacctt tagcaaaata gtcagctgac tgaaccgccc attcgacggg
    13261 aagctccact actaaatcca caccattttg taaagcttca ttcgcgcgat gccatttatc
    13321 gatgatagcc ggttcgcctc tttgcaaaaa attcccgctc attacagcaa tgacgacctc
    13381 tgctcctgtt atttttcgtg ccatttccac atgatagcga tgtccattgt gaaaaggatt
    13441 gtactctacg ataatcccgc agcttttcat gcgcatcctc cttcatagtt atcgataaaa
    13501 aagaaataga gacaagtaaa aaaaggcaaa aatcggaaaa aatacccgaa ctatataaac
    13561 tattctcgca aacacaatac ttctgcgacg aaaagctgca ctgcaagagc aatgcctata
    13621 tcgttcggat atataattta tgttgaagat ttattctttt cttgttaact cgagcaggca
    13681 aaaccgctag tctttgtatg ctacaaagaa ccagcgcttt gatttctctg atgctgcttc
    13741 gtctgtaaaa tcagaaaatg cttcgacttt cgaaaagccg ctgttttcca gcattcttaa
    13801 ataactttcc aatggatagg tacgctcttg atgtagttca tcttcacgaa taaatcgacc
    13861 agacccttct tgttcttcaa cgaaaaaggt aagaaaatgt tcgatgctgt gtttctcgct
    13921 tcctggataa ctatcccaca aaaaagcaaa attatcccct tgataatgat agctatattc
    13981 tggaaaaacc tcatctactt gataggtgga gtgtacgtca aataaaaatc ggccattttc
    14041 ttctaacgct tgatagactt catcaaacac ttgctgtacc tcttgtctat ttttcatata
    14101 gcacagcgaa tcagaaaaac aggtaattgc ctgatattgt ccgatttctg ataaatcgag
    14161 catattgcct tccacaaatt ggatcgatgc gtcttcttca tatgctcgct ggctggcaat
    14221 catcaacatc tcttctgaaa ggtctaaccc tgtcacttta tatccatctt ttgcaaaggc
    14281 aaccgctaat gctccagtac cgcatgccag ttccaaaata ttttttgtgt cttcttgtaa
    14341 atgacgtttc gaaaaagcta accattgctg ataaagtgtt tcgtccatca cttcatcgta
    14401 aatgaaagca aatgtttcat aagccatatg ttaatccaac cattcactaa gatcgactag
    14461 cggagcatct gaccatagtt tttccagatt atagaaattt cgttctggcg catggaaaac
    14521 atgtacgatc acatctccaa gatcgatcaa tacccatttt ccgccttctt ttccttcaat
    14581 acgttttact tcatatttgt tttcttcttc tttatcaatg atttcttctg taattgcgtt
    14641 gatttgacgt tcgctatttg ctgaacagat catgaaataa tctgccaaca aggaaacatt
    14701 tcgaacgtct aaagcgataa tgtcttctgc ccgttttgaa tctgctgctt caatcgcaat
    14761 ttttaattgt tctttactat ctatgatgat ttcctcctaa tatgagcagc ttattttttt
    14821 gctacccagt aattatatgt ttcgattgtt tttggataaa tctgttgttc ttgcgcaagc
    14881 aaatgggcca atgtatgttt tgtttcaaat gctacagctt cgtctagatc agcccatgca
    14941 atggctcgtg catcttgtac cccaggaaaa tctcgacctg gttcaatata gtctgctaca
    15001 taaatgattt tgtcaaggag actcatctta gcagccccag tcgtatgcac ccggattgca
    15061 tgaagaatct ctgcatcggt gattcctaat tcccgctcta caaacgaagc gccaacaaga
    15121 ccatgccaga ttgcattatt ataattcaat aactccggat caaaaccgtc tcttacgatt
    15181 accattttga actcctcatc tggtcgttct tttgcataat catgtgtcaa tgcagcaata
    15241 ctagcttttt caggagaagc accgtatttt ttggcaagag ccacggctgt ttcttctact
    15301 ccaagcacat gcttgaagcg ttgttcgctc attctcatct gtattttttg catcaggttt
    15361 tctctagaat aagcagtata ttcattacta tagtccatat tcatacaacc cttcattttg
    15421 aatataatca attactttat ctggaacaag gtagcggata gaacagcctt ctttgatctt
    15481 ttgacgtatt ttcgtggaac tgatgtcgat ctcaggtaca tctacccaaa ttacaggata
    15541 tggagtatcc gttgtgtatc ctggtcgacg tatacccaca aagttgacca tagaagtcag
    15601 ctcatcgatt ttataccatt ttggcaaata ttctaccata tccccaccga taataaagta
    15661 ataatctgta tccggattgt tttgcgtcaa ttccttcata gtatcatagg tgtaactttt
    15721 cccaccacga gctaattcaa tcgtttcaat ctgcaaaaaa ggattgtctt ccaccgctaa
    15781 ttccaacatg ttgagtcgat gttttgcatc aatcgtctgt ttctcatcaa catgaggtgg
    15841 ctgataagaa ggcatcaaaa atacgcggtc aagacctaaa ttccggccag cttgttcagc
    15901 catcactaaa tgtgcaaggt gaacgggatt gaatgttccg cccaagatcc ctacttgctt
    15961 tttcttctct aagaattgag gcatttcttc aggaaataat tgtgaacgaa caaatgtctt
    16021 agcttgcgta ttcatcatgg tcactcctta tattgctttt acttcttttg atagcctttg
    16081 atacttttct tttgtggaag gtttgtataa tacaataaca cgtccaatga tttggacgat
    16141 ttcgcaatct atttcttttt ctaatacttg agctgcttct tctgcaatct catctgtatt
    16201 ttgaagtaac gatactttga tcagttctct tttttctaaa gcttcttcaa tttgaacgat
    16261 cattgctgaa ttgatcccac cttttccgat ttgaaaaatc ggctgaagat gatgcgcttt
    16321 gctacgtaaa aaacgctttt gttttcctct taaactcata attttccttc ttccttaaat
    16381 caatgctttg cgtttcaata catctacacc ctttggcgcc cagcccgcaa ttactactgg
    16441 cgctgttaca gtgatccagc ctagaccggc aaaaacgatg tctgtttttt ctttcacaga
    16501 aaactcaaaa cgaacaagct ccggaaatgc ctcgacttca tcaggacgag gaggctgtaa
    16561 taatccacct acatgttttt gataaaattc gtctgctttt tccagtttcg ttcgatgaat
    16621 atttacatca tttgacacat aagcaataaa tgaagcacga ttgccgctga taaaatcaaa
    16681 tcttgcaagt ccgcccaaga aaagtgtttg cccttcattc agctgataaa ctttaggttt
    16741 gatttctttt aacggtgcaa tgatccgcaa atctttttta cctaagtagt gcgccatttg
    16801 atggcgatgg ataattcccg gtgtatcaat caaaaaatgc ccgtcatcta aaggaatctc
    16861 gattttatcc aaggtcgttc ctggaaactg cgaagttgtg attacatctt gtactcccgc
    16921 tgtatttttg atgatttgat tgataagcgt cgattttccg acatttgtta ctccgacgat
    16981 atagacatcc cgtccatcgc ggtattcttc gattttttct aatagttccg tcatctcatg
    17041 agatttctta gcactagtta ataatacatc tactggacga attcctgctt cgtaagcacg
    17101 ttccttcatc cattgtgtta atttagtttt tttcaatgat ttaggtaata tatccacttt
    17161 gttcccaact aaaagtactg gattgtcacc gacaaaacgg tgtagtcctg ggattagtga
    17221 accattgaag tcaaaaatat ccaccacatt gacgatcaat gcatcttttt gccctaattc
    17281 attcagtaag cgcaaaaagt cgtcatccgt caatgagaca tcttggatct cattataatg
    17341 gcgtaatctg aaacaacgct gacaatagac ttccccggaa gctaaacctt tttccaaagc
    17401 cgtttgcggc gtgtatccta attcaccggg tttgtttgtt tgtataacgg caccacagcc
    17461 gatacattgt aattcttctg tcattcgatt ccacctcgcc agcccatatc agggtgtttt
    17521 gctaatagat aggccataat tcttttttcc caaaaacgat taaattgtgt cttccaacta
    17581 tctgttgcga taatgggttt tacaaggatg ctacgtatcc ctgcacgatt ggctccacgt
    17641 atatcagtca taatctgatc gcctaccatt actatctcat catctgctaa atccaattgt
    17701 ttctttgcta tgttgatccc tcttgctaaa ggtttcattg ctcgtgcaac atacaaaaga
    17761 tcaaattttt caatcgctcg cgcgacacgt tttgaattat tgtttgaaac aacaacaaca
    17821 gggattcctg catttttcat ttctaaaatc caagtaagca actcttctgt tccatctgga
    17881 ttattccatg caatcaacgt attgtctaaa tcggtcaata ctgctttgat gcctagattc
    17941 tttaattggg caggtgtaat ctgatagatg gcttctacca tccatgttgg tttgtaattt
    18001 gaaaacatgc tgtctcctca tctgcaaaaa atgaaggagc acataaagta ctcctcaacc
    18061 ccgtattata ctgcatatca gcaaaaaaaa ctacctctat actcgttcgt ctttcagaaa
    18121 aagcatttct ttacaaaatg accaaaaata aagattgatc acagaaaaat ttagaaacaa
    18181 aaaacaacta atattggcgg aacctcttgt atcgtttttc cagtaattta tgctgatcta
    18241 atcgaacaag ttccgtcaat ctttcaatca acgctttttt cataatgtgt gcgactttat
    18301 atcgtggcaa ctgctcgccg ttgaacgttt caggaataac tcgatcaacg attcctaact
    18361 cgcgtagttc tggcgcagta attttcatca actcagctgc ttctgcggcg cgactaccgt
    18421 ctttccacaa aatcgacgca aatccttctg gagaaagcac agcataaatc gtttcttcca
    18481 gcatccagac ttcatccgct aaacctagag caagggcacc gccacttcca ccttcaccaa
    18541 tgatgatggc gatgatcggt acctttaaat cagacatttc gagcagattt ctggcaatag
    18601 cctctccttc gccgcgctct tctgctccta caccgcaata tgcacctgct gtattgatca
    18661 aggtaatcac cggtctattg aacttttccg cttgtttcat cagtcgtaaa gcttttcgat
    18721 agccttcagg atggggagaa ccaaaatttc tgcggatatt ttcctgcaga tcccgtcctt
    18781 tttgaatacc gatcactgtt accggtttgc catctaatcg agcgattcca ccaacaatcg
    18841 cttcgtcatc tgcaaataaa cgatcaccat ggcattcctc gaaagaatcg aagatctctt
    18901 caaaaaaatc caagcttgtc catcgttctt tagctcttgc taactgaacg acatcatgtg
    18961 ctgtcttatc cacgatctat ccatcctttc tgtgtatgca attcaagaag cgtatggatt
    19021 ttctgtttca attccatgcg gggaacaatc tgatcgacaa aaccatgaga taataagaat
    19081 tcagcctttt ggaaatcttc tggaagttcc tgcttgatcg tctgttcgat gacgcgtctt
    19141 ccagcaaaac cgatcaagct ttggggttct gctagaataa tatcgccttc cattgcaaaa
    19201 ctggcagtta ctcctccggt cgtcgggtcc gttaaaacag ttagataaaa aagaccttca
    19261 ttgctatgcc gtttgacagc agcagagatt tttgccatct gcattagaga aaagattcct
    19321 tcttgcatcc gtgcgccacc tgaagctgtg aacaagacga ctggaagact ttcctttgtt
    19381 gctcgttcga ataatctggt gatcttttct ccgacaatcg ttcccatact tcccatgata
    19441 aaattaggat ccatcactcc aataatgaag ggaatcccct gaatggttgc tttaccagtg
    19501 aggactgctt catgaagtcc tgttttatct tgcatttttt taattttttc cgtatattcg
    19561 ggaaatgcta gcggatcttt ggttacaaga tccgtatccc attcttcaaa acttttttca
    19621 tcaataatca aagctagacg ctgccatgca ccgattcgaa aagcgtatcc gcaatgaggg
    19681 catacttttt cttcaccgat gtctttcgta taaaggatat gtttgcaatt tggacacttt
    19741 gcccacatgt tatcaggaac agatggcgag ttagcaggtt tgctctctct attaggattg
    19801 atccgaatat atttcttttt cttaaacaga gccatctatg cgcctcctat ctccgtttct
    19861 ggtgtccaat tcggtaaaaa ttcttcttgt aaaaatgctg tgctgtaatc acctgctatg
    19921 actgcaggat gactaatcaa atccatctga aattctgcgt tcgtgatgat tccttctgtg
    19981 ataaattcac ttaaggctcg ctgcatcttc attaatgctt caaaacgcgt atttccatgg
    20041 acgattattt ttgcaatcat tgaatcataa tatggcggga tcgtatatcc cgggtaaact
    20101 gcactgtcta ctcgcagtcc catcccacct gctggaagca gtaagttttg gatcttccct
    20161 ggagaaggag caaaatggaa agcaggattt tctgcattaa tccggcattc gattgcgtgt
    20221 ccttggaata ctacttcttc ttgacacaca ttcaaaggct caccggctgc tatctccacc
    20281 tgttttttta ctaaatcgat tcctgtgacc atttctgtta ctggatgttc cacttggatt
    20341 cgagtattca tttccatgaa ataaaaatcg ccttcttcat ccatcagaaa ctcgatcgtt
    20401 ccggcatttt cataattgac tgctttagct gctcgaacag cagcgtctcc tagtgcttct
    20461 ctttttgttt gtgagatcac tacagaagga gattcttcca gtactttttg attgttgcgt
    20521 tgtaaagaac aatctcgctc gcctaaatga atgacatgac caaatcgatc acctaagatc
    20581 tgaacttcta tatggcgagc aggataaatg attttttcca aatacatatc atcatttcca
    20641 aatgccgctg ctgcttcttg ctgagctgaa gaaaaatgct gtgggagctc ttcttttgat
    20701 tgaactttcc gaatgccttt cccgccacca cctgcagctg ctttcagcat cactggataa
    20761 ccaattctgt ctgctatttc caatgcttct tctactgtag ataatacacc agtacttcct
    20821 ggaatgactg ggacatttgc ttcttgcatc aattgacgcg cattgatctt atttcccatt
    20881 gcatcgatcg ttgcactttt aggaccaata aatgtgatat tgcactcttc acacatggag
    20941 gcaaatcggc tattttcaga taaaaaacca aatcctggat gaattgcttc ggcttttgtc
    21001 acgattgcag cgctcagtac ttcctgaaca ttcagatatg aatcaacggc ttttgccggg
    21061 ccaatgcaga ttgcttcatc tgctaactgt gtatgaagtg cttcggcatc tgcttctgaa
    21121 tatatcgcta cggtttggat ccctagttcg cggcatgcac gaatgatacg tacagcgatt
    21181 tcaccgcggt tagctatcaa tactttagaa aacatatttc acctatccaa tcataaaggt
    21241 taattccgct tcggctactt ttttaccgtc tactttagcg attcctttgc ctattccggc
    21301 tgaagctttc actttcaata tctcaacttc aaggtataag gtatctcccg gtgtaacttt
    21361 cttacggaat tttgctttgt ccaatccgcc gaaataagcc gtctttccct tgaattgttc
    21421 aagagaaagt aatgcaactg ctcctgcttg agccattgct tcaacaatca atacccctgg
    21481 cataacaggt tcttctggaa aatgtccttg aaaaaagggc tcattgatcg ttacattttt
    21541 cttagcaacg atccgttctc cttcaaccat ttcttccact cgatcaatca aaagcattgg
    21601 ataacgatgt ggaatgattt cttttatttc ttgtatgttc attgttttcc ctctttcctg
    21661 ctttgcttat ttttgctgaa tcctaaagag tggctgtcca tattcgacaa ctgactcgtt
    21721 ttctacaagg atttctgtga tcactccgtc ggcctcacta gttatctcat tcatcagttt
    21781 catcgcttca ataatgcaga taacttctcc tttggcaact tgatcaccta cttttttgaa
    21841 agctggtttg tcgggcgctg gttgcagata aacgattccc acgattggcg aaacaacctc
    21901 gattccatca aatactgccg attctttttc tttcattatt tctggagcag ttgttgcttg
    21961 ttcagatatg acattgactg gctccgaaac tggcaacgtt tcgtttgttt gaaccatatt
    22021 catgcctcga cttgttttat ttttattcat atacaattca aattgacctt cacgcaaatc
    22081 gaattccgtt agcgaggatt gatcaaattg actgactaat tctctgattt cattgatatc
    22141 caaaattatt cctcccagcg tttcatgcac agaaccgcat tatgtccgcc aaaccctaat
    22201 gaattactca ttgcataagt aaaacttgca ggtttgcttt cgtttttgac aactgtcaag
    22261 tcaatctcag gatcttgttt ttctacattg atcgtaggtg ggataaattg atgttctaat
    22321 gccagcaaag ttgccaaggc ttcgatcccg ccggctgctc ccaataaatg tccagtcatc
    22381 gatttcgtgc tgctgacgta agtatctctg aaattttcac ctaatgcgat ttggattgct
    22441 tttgcttctg cctggtcatt ggctggtgta cttgttccgt gagcattgat atatccgact
    22501 tgttccggct gtacaccagc ttcttccatc gcaagcttca ttgctttaga tgcaccagaa
    22561 ccatctggag taggagctgt catatggtaa gcgtcacagt ttgcaccgta tccaacgatt
    22621 tctccataga ttttggcacc gcgagcttgt gcatgttcta aagattcaag aactagaacg
    22681 cctgctcctt cacccatcac aaaaccattc cgattttcgt caaacggaat cgaaccacga
    22741 ttaggatcag ttgattctga gagtgctgtt aaagctgcaa atccagcaat ccccatctca
    22801 caaatcgttg cttctgttcc tccagcaaga atgacatcag aatagccatg tttgatgtta
    22861 cggaatgctt ccccaattga attcgttccg ctagcacaag ctgttacgat agctgtacaa
    22921 ataccttttg cacctacacg caaagcaata tttccagctg ccatgttggc aatcgccatt
    22981 ggtacgaaca ttggagaaac tcgttttgca cctttttcat gtagacgaat aacttggttt
    23041 tcgattgttg gaagaccacc gatcccagat ccgatgatga cgccaaaccg gtcttgattc
    23101 attttttctt tatctaaacc gctcatctcc attgcttcta aagcagcgta gattccatag
    23161 atcgaaaaca tatccattcg tttgctatct tttttaataa aatatttatc gtaagggaaa
    23221 tctttgactt cacccgctaa ggtaatccct gtttctgaag catcaaattt agtgatcggt
    23281 gcgatgccat tcgtcccctc ttttaagcta ttcaaaaagc tgtctgcgtc atttccaata
    23341 ggtgaagtga ctccatagcc agtaattacc actcgattca tttgtttgct ctccttttct
    23401 tatccgtgca tgaccaatcc gccatcgaca ttgatgactt gtccggtgat atatggattt
    23461 tgtgctaaga aaactgctgt ttgtgcaata tcttctactt gtccgaaacg ctgcatcgga
    23521 atttgctttt ccgcttgttc cttgactttg tctgctaaaa cttccgtcat atcagttgtg
    23581 atgaatcctg gcgcaatggc attacatgta atgcctctag ttgcagcttc tcgtgccaca
    23641 gattttgtta atcctactac gccagcttta ctagctgcat aatttgcttg accaatattt
    23701 ccaatcaacc cagatacact agagagatta atgatggccc cttctcgctg cttcatcatt
    23761 tttttcaata cgtgctgcgt catattgaag gttccaatca aattgatatc cagacatttt
    23821 ttgaaatctt ctgcatccat tcgcatcaca agtttgtcat ttgtgattcc ggcattgttt
    23881 actaacacat ggatcgatcc aagcttttct tctgcttctt tgatcatttg tcccgctttc
    23941 tcataatcag agatgtcacc ggaaactcct acgcatttta caccgaatgc ttcgatttct
    24001 tctatctttt cttttggaat ctctccgcga ccattcaaaa tgatatttgc tccagctttt
    24061 gcaaaagcta aggccatcgc tttgccgatt cctcttgtac tacctgtgat aaatacattt
    24121 tttcctttta catccataac gttcctcctt atagtattgc tattgtttca tcaaatgtct
    24181 gcttattctc aacacgcaga actggtattg ttttatcgat ttttttcata aatccgctta
    24241 atacttttcc ggggccgact tcgatgactt gttcgatgcc gattgttttt aacttatgga
    24301 tactctcata gaaacgaaca ggttgcatga cttgctgttc aagtagtccc gcgattgttt
    24361 ctttcttcat tatttccgtt gttgtgttgc ttatgatagg aaaagaaggt tcagagaatt
    24421 gaatctgact taggtccttc gccagttttt ttgctgccgg ttctaaaata gctgtatgaa
    24481 aaggcccgct gacatttaga gggatcattc ttttgaaccc tttttctttt aatagtaaaa
    24541 cagcttcgtc tactgctttt tcttcgccac caatcacgat ctgctgaggt gtattataat
    24601 ttgcaggaga tacgatgccg tacttgctag cttcatgaca gctttcctcg atcgtttcaa
    24661 tcggcgcatt catcactgca accattttcc cgcttccagc tggggtagct tctgtcatat
    24721 aagcgcctct ttttgctact aacgcaactg cttcagtgaa ggatagcgca ttactagcta
    24781 ctaatgccga atattctcct aaactcagtc ctaaagctgc atctgggatg attccatgct
    24841 ccttcaataa gcgataatac gcgatgctga ctgttagaat agctggctgt gtatattgcg
    24901 tctgatccaa acgttcattt tctgtaaagc aaagttcagc catatcgtag ccgagaatct
    24961 cacttgcttc atcaaatgtc tgctttacaa cggcttcttc atataaatct tttcccatac
    25021 cttgatattg tgcaccttgg ccactaaata agaatgctgt tttcatgttt ttctccaata
    25081 tatccagaat atatgtttga ttcttcctat tcaaaaaggc cgagacattc ctatttcagg
    25141 aaatgtccca gcccccaacc taattttaat gattatgcag tttgtttttc tacgtaagtc
    25201 actaaatctt gaaccgtttt gattccgtct tctgtttcga ttttcacgtc aaattcatct
    25261 tcaatttcat tgatgatttg gaataaatcc aagctgtcag cttctaagtc ttcttggatg
    25321 tcagtagtca atttgatttc ttcagtttct tttcctaatt cttctgcgat gatttcttga
    25381 attttttcga ataccataat aatatattcc tccgatattg tttgcttttt atttttataa
    25441 tttaacagtc tacaactcca tgagaatact tccccatgtt aaacctccgc catagcctgt
    25501 aaatattact ttctgctgtt ttcctaaggt gatctttcca ctagaaactg cttcatccaa
    25561 taagataggg atgcttgcag cagatgtatt cccatattta tccatattgg tcaggaactt
    25621 ttcttgcggc atctttactt ttcgggcaat tttctcaata attctgaggt ttgcctgatg
    25681 caaaagcaga taatcaactg gtttgtcttt catgacttct tggatattgt ttgcaacgtc
    25741 tcgtacggca aaatcaaaaa tatctctgcc agtcatttgc aaataatacg aaccttctga
    25801 atcttctgaa tagaacggat ttttattttg ctggtagcca gcggtcaatg agctacttct
    25861 ggtaccgtca gctgctaatt tttctttcag caattttttc tgtggattcg cttctaagag
    25921 aatcccacct gctccatcgc caaacaacac agcagtcgta cgatcagacc aatcgattag
    25981 cttagatagt gtttcaccac caatcaccag tcccttagtt gagccgcagc ggatcatttt
    26041 ttcagccatg cttaacgcat aaacaaatcc tgagcacgca gcactgatat caaaagcgat
    26101 agcatgagtt gctcccaatt tcccttgtac ttgtgctgct acagatggtg tcgtgtaatc
    26161 gggcgacatt gttgctacta aaataaaatc caaatcttta gggtttagat ttttctgttt
    26221 tatcaatttt tccgccacta aaatgcataa atcagaagtc tcctgatttg ttacacatct
    26281 tcgttcacga atacccgtcc ttgacgaaat ccattcatca gaggtatcca tcatcttgga
    26341 aagatcatta ttagtaataa tcttttcagg aaggacgctg gctgttgcag taatcattcc
    26401 aaattgttcc attaaatatc ctcacttata gtcttgcaag aagtcgtgca agtttttcag
    26461 tgcatccagc aaggcatgct gttcctccgt agccattccg tctaagatgt tcttgaccat
    26521 ttcacgatga aaatgctgat ggacccgaaa tagtaacttt ccttttttcg ttagtcccaa
    26581 ctttacaacg cggcggtcat cttcactgcg gatacgttcg acatagcctt tttttactaa
    26641 cttgttaata gcagtggtca aggtcccaac agtaattgat agttctttgg ctacttctga
    26701 agttgttttt ttcttgtaca tcccgattgc ctcgatcgtg tgcatctctg tgattgacag
    26761 atctttgaat tgagattttt tcagctcaga ctcttcgatt gtcaaaatat cattgaagac
    26821 actaacaaga taatcattta ctgtttttaa atctggttcc atgttccacc gtccactaat
    26881 tagtttgatt atcaaatctt ttgatgttca aactatatct taactttttt caaaatgcaa
    26941 ccttaaaaga tcattttttt actatatgag ctttttttaa gattttactc atttaaaaca
    27001 actgataaat cagcatttat aatttctttt attagaaaaa tcatctatct cacatatttt
    27061 gattatcaaa gtattttctg tgaacagaac tatagaattc cctaaaactt gtccattatt
    27121 tcaaaatttg ttatagtctt tttattcaaa gcgtaaaagg agatcctatg ttaaaagaaa
    27181 aaatgaaaac tctccccatg ctgccgggtg tctatcttat gaaagaccga gatggtaagg
    27241 tcatctatgt tggtaaagca aaacggctca aaaatagagt aagcagctat tttcatcaga
    27301 ataaacagca ttcaaaaaaa gtattacgta tgattcatca tataacagat tttgatttcg
    27361 tcgtagtaga cacggaatta gatgctttat tgctcgagtg tcaattgatc caacattacc
    27421 gtccttttta taaccgacaa atgaattatt tcagtaatta taattatgta catattacca
    27481 ataagggatt tgtattaaca gatactccta cggctcgaac atacgggcct tttcgtctct
    27541 ataaaaaaat gccgtctatt ttgcgtataa tggaagaaac ttatcaaatg ccttggttgt
    27601 ctgaaattag tttgttagct ttgcgagtcc agcttcctga cctacaggaa atgacttttg
    27661 aacagaaaaa aaaggaactc caagggctgt ttcaaggccg aaataaaaag ctactgactt
    27721 acttgaaaaa aagacaacaa catttcatct atcagttgaa tttcgaaaaa gccggtatgc
    27781 ttcaaaaaga tatcgaatta gttacttatt ttattagacg gatccaggaa caaaagcagt
    27841 ttttaagaac accatcgctc accttcagca tgccattagc agcagatgag agtcagaaaa
    27901 agcactacct cgtttgttat ggtcaacttg cagaaacaat gattacctct ggtgacgttt
    27961 ctcctgactt ctattatgaa aagaaagaag ctcatttatc tttgaaacgt caattgtcaa
    28021 aagaagaaat cgatcctgta caaatcttga tcagttaccg caaaaaatta gaaaaagaac
    28081 agtttgaaat tgaactgtta aacaaaaaag aagctgaaaa gcaactaaat tagttgcttc
    28141 tcggcttctt ttaggcatct tcaacttcaa atgtcaatta tcctaaaatt tattggatta
    28201 agtcatagat ttccatcgct acgatatcga tattatcaaa ttcgtattgc tgatgagtat
    28261 ctgtttcagt taattcaaat gtatcggtcg ctttatcata agttactgta cacttctcta
    28321 cgccttcttt ttcaaaacgg cgaacttgca gttcattatc tgctgactcg accatagcct
    28381 ccagtcgttt tatgattgcg actaattgtg aatgtgtcat cggaggtcct ccttttctta
    28441 tttctgttat attgtatcaa aagcatagcc tacttgcatt gattttctct aaaaaaactc
    28501 gttttttatg attttttttc tggtattttt ccttcaggcc accaaagttt gatcaaagct
    28561 tgggttccgt cattctcaaa acctttatct gccaactctt catatagttt caatgcttgg
    28621 gtagttgctg gcaatacaag atccattttt tctgcttctt ctaatgcaat ctttaaatct
    28681 ttgataaaat gtttgacaaa aaaaccaggt gtgtaatctt cttttaaaat acgaggagaa
    28741 taattgctta aagaccagtt agctgcactt ccacctgaaa gcgtctcaat cactttcttt
    28801 aaatcaagtc cgtttttttg tgcatagaca agcatttccg tcattcctgt catcgtacct
    28861 gcaatcatga tctgattagc catttttgta tgctgacctt tcccagcaga accatgcaat
    28921 gtaaatgtcg taccaaattc tttgaataaa ggcagtactt gatcataaac ggcttcttct
    28981 ccaccgacca tgatcgtcag tgtaccattc tttgctccta agtcaccacc ggataccggt
    29041 gcatctaacg catctgcgcc tttttctttt gctgtttttg caattttttc tgccaggctt
    29101 ggtgtacttg tagtcaaatc aactaaaata tgtcctgaga tatctgcaga aaaaatcccc
    29161 gactgtccat agtagatttc ttctacatct ttggggtaac ctaccattgt aaagagaata
    29221 ttactttgtt ctgctaccgc ttttggtgta tctgcccaga tagctccttc tgttactaaa
    29281 ggatcagctt ttgcttttgt ccgattatag acagctactt cgtgtcctgc ttctagtaga
    29341 tggcgtgcga cagcacttcc catgacgcct gttccgataa aaccaagttt cattttttcg
    29401 acctcctaaa aatcaaaaat ccttgcttct atgctagtat acgctagaaa caaggatttt
    29461 ttcataaaaa atgtttgaat tttatctttt aaatgaattt aattttattt tgattcgttc
    29521 aatcgagtct tcttcttctt ttcttcgcat ctcttcttca tgataaacaa ccatgtcttg
    29581 ataaaattcg atcatagctt cgccgaaatg tgtagatgaa atatcataaa gtttagcttc
    29641 taaaactttt ggatctttag gaacttcact ggaaatataa tcaataagtg ctggtgcaaa
    29701 gtcttcgtcg gtttcaaaag ttttccctaa tgaaggatga tcgaacaatc ggttcaaata
    29761 agcatttcct tccacgacac aaggtgttcc ggctgccatc gcttctgtat aagtaagccc
    29821 ttgtgtttct gaagtagaag cactgacaaa ataatctgcc gctttataat aaagtgctac
    29881 atcattgttg tccacttctc ctgtgaactg cacaaattct tctaactgca gttctgagat
    29941 caattcctct aactcttcta cataaggtcc ttttcctacg ataactaatc tggcgttagg
    30001 ataagcggag atgacctgag gaaacccatt aatcaaggct tggatatttt tctcataaga
    30061 aatcctgctt aaagaaagaa tcatcaaatg gttttcctga agacctagtg actcccttaa
    30121 tttgctgata tcctgctgag tgatatcaga acgtttgaat ttttcaatgt cgataccagt
    30181 aggaatcacg cgaagcggtg ctattacacc atagctgcgt aatgtatcaa taacacgttc
    30241 acttggacaa actacacctg tcgtatgatt tgcaaataat ctagacaagt attttacatg
    30301 ggattgcctg atcacttttc ctttacggat ataatgaagg tagtcttcat acatcgtatg
    30361 gtaagtatgg atcagaggta ttttcaactt cttagctacc atcttcccaa gtatccctgc
    30421 tccgaattct gtatgggtat gaataagatc tagttctagt tctttggcaa ccaaataagc
    30481 ataccacatg cctctaacaa caactcttcg atccttgaaa gaaataaatg gtacacttgg
    30541 cattcgaatc acatcttttt ccaacttatc cgcattagga tcggtcgttg taaaaatata
    30601 gacttcatgc ccatgtcttt ctaattcttg ttttaatgtt ttgatcgatg tagcaactcc
    30661 gctgacttgc ggaaagtagg tatcggtaaa aaagccgatt ttcatgtttt tcgcctccaa
    30721 actagtcctt gacctgattt acttttttta atttgctaga gactttttca ttcagtacac
    30781 tttcgtatac atttttaagt tcttcaccga ttttattgat acttcgctct tttgctgttt
    30841 gataaccggc ttgtgtcgta ctcggtagtt cttgattggt aatctgttgg atcagtcgga
    30901 taaattcttc gtttgtcttc cccatatagc agttcttgct atcttctaac cagccattat
    30961 acactggaat atctcgaaca agtacgtttt gtttgcttgc taaagcttct aaaacaacga
    31021 tcccttctgt ctcttcataa gaagggaaaa agaatagatc tgcacctgaa tacgcacctt
    31081 ctatgatctc tccacgaatg taaccaggaa acaggacatt ttcaggatga tcttctttta
    31141 caattttccg gatgttccga ggaatcgagt acatgggaac atgaccaaac caaataaatg
    31201 tgtattcggg catcttctta gcaatttcta cgaaatcaat gattccttta cgttcgaaaa
    31261 acaaaccgac acaaatgatt actttttgat ccggagacag tttgaaatat tctctgaact
    31321 tttgttcttt cattggatca gggtgatatt tctctaagtc gatcccattg gaaatagctt
    31381 gaatcggcac acggatacca tagctttcca acaactgttt tgaataaggt gttggcgtga
    31441 tcagatagtc cgctttttgg tacaatccta ccagatattt ttttacgata ggagaaagct
    31501 ggttcgatcc gataaaggaa tttcggaaat cttcctctgt agaatgcgca tgatagacaa
    31561 ctttttttcc ttctcttctg gctttattga ccatattatg actattgatt ccgtatgtat
    31621 tgatgtgcag gatgtcataa tcttcttttt catctagtgt ataagagata ccgacttccg
    31681 tcagagcacg tttttgatga tcaagcgcac gcccgattcc agattttgca agcatctttt
    31741 cactttcaaa atataataat accttcacct tacgtccccc ttcacttata tagtataaca
    31801 tagcctacaa actgtcactc aaacttaagc cctatttttg tctattctta ctgacaaaaa
    31861 cgttttctta aaaaagaaca aaaaaactgg cgtagctctt ttacaagcca caccagcttt
    31921 tgatacgttg tttattttac atattcatga acaagttcaa cgacttcttc catcatatcg
    31981 cattctttca atgcacgatc agcaagttca gccattttcg ctgtgtccaa gcgtttcatt
    32041 aaactacgcg ttttaagaat agatgtcgca ctcattgaga actcatctag acccatacct
    32101 actagcaatg gaacagctgt ttgatctcca gccatttctc cacacatacc tgcccatttt
    32161 ccttcagcgt gtgctgcatc aattacattt ttgatcaaac gtaaaattga tgggttatat
    32221 ggttggtaca agtaagaaac gcgttcgttc atacggtctg ctgccattgt gtattgaatc
    32281 aaatcgttcg tacctacaga gaagaaatct acttcttttg caaacttgtc tgctaagact
    32341 gctgctgctg gaatctcgat catgatgccg acttggatcg tatcagatac ttccttgcct
    32401 tcacttatca atttttgttt ttcttcttca aagatcgctt ttgctgcgcg gaattctttg
    32461 agtgtagcta ccatagggaa catgatacgt aaattaccat gaacagatgc acgaagcaat
    32521 gcacgcattt gtgtacggaa catttcgtcg ccttgttcag ataaactgat acgcaatgca
    32581 cgatatccta agaatggatt catttcatga ggtaattgca gatatggtag ttctttatct
    32641 ccaccgatgt ccattgtacg aacaactaca ggttttcctt ccataccttc taatacagct
    32701 ttgtaagctt catattggtc atcttctgtt gggaagtctg gagaatccat atacaggaat
    32761 tcagtacggt acagaccaac tgcttctcca ccattattat ggacaccaac tagatctttt
    32821 ggtgttccga tgtttgcagc taattcaaaa tgcttgccgt cagctgtgac agtttctgca
    32881 ttttttaatt tttcccattc tgctttttgt gctgcgtaat ctgcacctgc tttttcaaat
    32941 tcagcttttt gttcatctgt aggatcgatg attacatcgc cttcgatccc gttgacagcc
    33001 aaaatatcgc cttctttgac tttagcagta atttcttttg tcccaacgat tgctggaatt
    33061 tctaaagaac gtgccatgat agcagaatgt gaagtacgtc caccaatgtc tgttacaaac
    33121 gcttttacaa aattgcgatc taattgtgct gtatcacttg gagtcaagtc atgtgcaaca
    33181 acgaccactt cttcgttgat cattgatgga tttggtaaag taacgcctaa taagtgcgct
    33241 aaaatacgtt tagcaacgtc acgaatatct gcagcacgct cttgcatata agcattatct
    33301 tccattgctt cgaacatacc gatatacata tccgttactt cttttagcgc tgattcagca
    33361 tttacgctgt tgtctttaat attttgcttg atttgaccta ccatttctgg atctgaaaga
    33421 accatcaaat gggcatcaaa tacttgcgct tctgcttcac ctaagctttg cgctgctttt
    33481 tcacgaattt gctgcaattc ttcagtagat ttagctaatg cagcatccaa acgagcttct
    33541 tcagccgcag tatcttctac tgttgcctta ctgaatgtta aatccggttg aactagcagg
    33601 taagcttttg caacggctac accgtcacta gcggcaatcc cttttagcat ttcaaccatt
    33661 attcagataa gccttctttc ttcattgttt caacgattgc tgccattgca tcagcttcgt
    33721 cagcaccttc tgcagtaata gtaacatcag aaccttgacc tacacctaaa gacataacgc
    33781 ccatgattga tttcaagttt actgatttac ctttatactc taagtttaca tcagagttaa
    33841 atttgcttgc tgtttgtact aatagtgtag ctggacgagc gtggatccca gtttctgcta
    33901 ctacgtgaaa ttctttcttt tccatattaa tcggtctcct ttaagtgagt gttgttttta
    33961 tgtgagggtt ttctttttta gtaattcaga gaatcctaac aaatgccacc ctttcatctg
    34021 taaagattaa catttttttt cgttagatac aacagttttc attcaatttc agataaaagt
    34081 attcaaatta ttccggattc tttttcatcc ttttcttcac attttataac aaacgtgttt
    34141 atttcctttt tcttgtcgct ttctcttctc ctgacgttta tcattctttc ctttgaccct
    34201 ctttgttttc atatgaaacg aattacttgc ttcccttttt atttttagta taataagagt
    34261 caaaggtcag gaatggtcaa tagagatttc accttttcta cctcataaat ctcttaaaaa
    34321 actaggggtt attcttttac ctcatgaaaa acgagatgta aaatatggat gtacccattt
    34381 ttgtgaaagg acgtgaatga ttcatgcttt gtcaaaactg cggcaagaat gaggcaacga
    34441 ttcacttgta tgccactgtc aatggtcagc ggacacaact cgattactgt cagagctgtt
    34501 atcaaaaaat caaaaatcaa caaaatggag gtctgactaa tatggcccaa aatgatccat
    34561 ttggatttgg cagtttggac gatcttttcc gttccatgtc tcgccaaatg caacagcaag
    34621 gaaattatga gcaaacacca ccaacacaat ttggcggaaa caacaacttc aatggtggtc
    34681 agccacctca aggcaataca gaaggtttat tgggagaata cggaatcaat atcacagaac
    34741 aagcacgaca aggtgatatc gatcctgtga tcggacgcga tgacgaaatc aaacgagtca
    34801 ttgaaatttt aaatcgccga accaagaaca atcctgtctt gattggagaa ccaggtgttg
    34861 gtaaaacagc agttgttgaa ggtttagcac aaaaaatcgt agatggtgat gtaccgcaaa
    34921 aattaatgga caaagaagtc attcgtttag atgtcgtatc tttagtccaa ggtactggta
    34981 tacgaggaca atttgaagaa cgtatgcaaa aattgattga agagatccgt caagcagaaa
    35041 atgtgatcct attcatagat gaagttcacg aaatcgtcgg tgctggttct gctggtgatg
    35101 gaaatatgga tgctggtaat attttaaaac cagctttagc tcgaggagaa ttgcaaatgg
    35161 ttggtgctac taccttaaat gagtaccgca tcatcgaaaa agacgctgct ttagaacgtc
    35221 gtatgcaacc tgtacgggta gatgaaccaa ctgtcgaaga aacgatcagt attttgaaag
    35281 gtttgcaaaa acgttatgaa gactatcatc atgtaaaata tactgatgag gccatcgaag
    35341 cagccgcaac tttatccaat cgttacgtcc aagatcgctt cttgccggat aaagccatcg
    35401 atttgctaga tgaaacaggt tctaagaaaa acttgacgat ccaaatcgtt gatcctaaaa
    35461 caatcgagaa aaaactgcaa gaagcagaag aacaaaaagt tttagcttct cgagaagaag
    35521 atttcgaaaa agcagcttat tatcgcgatc agatcaataa acttcaaaaa atgaaagaac
    35581 gtcagctcac tgaagaggaa acacctgtga ttaccgaaaa agatatggaa aaaatcgttg
    35641 aacaacggac aggtattcca gtgggtgaat taaaagaaaa agaacagaca caactgaaaa
    35701 acttagcaga tgacttgaaa gctcatgtca tcggacaaga taacgctgta gatcgagtag
    35761 cgaaagcgat tcgccgaaac cgtgttggat taaacaaaca gaatcgtcca atcggctcct
    35821 tcttatttgt tggaccaact ggtgtaggta aaacagagct tgcgaaacaa cttgcctacg
    35881 aactattcgg ttcacaagat tcaatgattc gtttcgatat gtctgaatat atggaaaaac
    35941 atagtgtctc taaattgatt ggttctcctc caggttatgt cggatacgaa gaagctggtc
    36001 aattaacaga aaaagtacgg agaaatcctt acagtcttgt cttgttagat gaagtagaaa
    36061 aagctcatcc agatgttttg catatgttct tgcaaatctt agatgatggt cgattgacag
    36121 atgcacaagg aagaacggtc agctttaaag atacgatcat cattatgaca agtaatgccg
    36181 gaactggtaa agtagaagca aacgttggtt ttggtgcggc acgcgaaggt gttactcgtt
    36241 ctgtattgaa ccaattaaac aactacttta caccagaatt tctgaaccgt tttgacggga
    36301 tcatcgaatt cagtgcatta tcaaaagaaa acttgatgac aatcgtcaca ctaatgctag
    36361 acgatgtcaa ccaaatgctg gcagcacagc aacttcacat cgaagttcct acgaatgtca
    36421 aagaaaaatt agttgactta ggctatgatc catctatggg tgctcgtcct cttcgacgca
    36481 cgatccaaga acaaatcgaa gatggtatcg ctgaatttta tcttgatcac ccttctatcc
    36541 atgagttgaa agcaaaactg gataaagatg gaaaaatcat cgttacttct aaaccagaac
    36601 gtttggctaa agaatcagcc gaagaaacgg ctgaataaat ccagttttat agcgtgagac
    36661 ggtatttctt tgagaaatgc cgtctcattc ttttttcaga aaagtcaaaa tactgttcat
    36721 tttataaaaa agaaattata ataagagaaa caagcaatta aaaatacata aaagaggtga
    36781 gcgccatgaa attggtaaat gtaacaaaca gccattcccg tcttgtatta aaccagcttg
    36841 aaaacactga tgcccatcta gtcaaggtct acacagccgg aaataccact attgtctaca
    36901 ctgaagcccc tgaacataat gaaattctgc tgatcaatga caaacgtaaa atccagccga
    36961 aagaaatcga agatgctaaa aattatttct tagataaaat caaagacgcc gtttaccacg
    37021 aggatgaaat caaagtaatc gaattggcag gccttgttga aatctcgatt ccaaaacatg
    37081 aattaggcgc tacattagcc gtgtaaacaa attttgaaca taataattaa agagcgtggg
    37141 acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc gaaagcagaa
    37201 gcaactcctt cggaaataag ctgaaattca cgaaaattgc ttttcaaatt tttgtgaatt
    37261 ccagcttatt tcttggagtt aaacgcttct gtctcagcct ctttttcttt ctagcttttt
    37321 gatttttctc ttttcttttg tacttttctc ttttcatttt cagttctacg cgtgtcttta
    37381 tttttaactt tttcctcttt atggatgatt gatcgtactt tttgtgcaat ttgctcgttt
    37441 ttgtcccagt cttttacatc taataatcga cataatcgta acatctcttc ttttttctgt
    37501 ttttttcttt cacgtctttg ccattctgtt tccatgtgtc acactctcct ttctttaatc
    37561 atatgtacgc aaaataattt ttatattttt ttgattagac atttctatga ttttaatata
    37621 gtaaaaagag ccgtcacgga aaatccgtca cggctctaaa caaaatatga gaggctgttt
    37681 ttgtttggct attcttatta cttgatgcag ggcagcttgt gtcaagactt ctttacatca
    37741 aactttttaa ttttacattg ggatatttat ccgcaaacca gcgttctgca aattggttct
    37801 cgaataagaa caacggttgg tcgaaacggt cacgagccaa gatattgcga cttgaactca
    37861 tcttctcatc caaatcttct ggatcgatcc agcgagcgat tttgtgtccc attggagaca
    37921 tgattacttc ggcgttatac tcatttaaca tacgatattg gaatacttcg aattgtagct
    37981 gaccaacagc tccaatgata tattcttccg ttagatatgt tttataaagc tgaatcgctc
    38041 cttcttgaac taattgatag attcctttgt ggaaggattt ttgtttcatg acattttttg
    38101 cagtcacttt cataaacagc tctggagtaa atgaagggag ttcttcataa gcaactttta
    38161 gttttccttc gaacaatgta tccccaatct gataattgcc tgtatcatat acaccgatga
    38221 tatcgcctgc tactgctttt tcgacgtttt ctctcgaatc tgccataaat tgtgtgacat
    38281 tgcttaattt cagtttttta tttgtacgtt ccaaccagac atccattcct cgttcgaatg
    38341 ttccagaaca gattcggaca aaagcgattc ggtcacgatg ggctggattc atatttgctt
    38401 ggatcttgaa tacgaaacct gaaaattctt cctcataagg acttaccatc tgatcatctt
    38461 gtgttttgtg tccataagga gctggtgcca attcaacgaa agtctctaaa aaagtctgta
    38521 caccgaagtt agtcaatgca gaaccaaaaa atactggtgt ctgatcgcca cgagcaattt
    38581 tttcttgatt aaatgcatct ccagcctctt tgattagttc tacttcttct aagacttgtt
    38641 catataagga attttcagtt agaggatgat tttcgggaag cagtccatct tcatccaatt
    38701 ctactaatcg ttcatcctga taattttccg gacgataaaa ctctacacga ttatggtaga
    38761 tatcataaag accttctagc cctttaccca taccgattgg ccaattcatc ggataagatt
    38821 cgatatctaa tagctcttct aattcttcta acaattccaa tggttcacga ccatcacgat
    38881 ctagtttgtt gataaaagta aatatcggga tgccacgttt ttttacaact tggaataatt
    38941 tctttgtctg tgcttcgatc ccttttgcac tatcgattac catgaccgca ctatccacgg
    39001 ccatcaaagt acgataagta tcttcagaaa aatcttcatg tcctggtgta tccaagatat
    39061 ttactcgttt cccttgataa tcaaactgca taacagaact agtaacagaa atcccacgtt
    39121 gtttctcgat ttccatccag tctgatttgg caaaattacc tgtttttttg ccttttacgg
    39181 tcccggcttg acggatagcc ccaccaaaca atagtaattg ttctgtaatc gttgttttcc
    39241 cagcatccgg atgggaaatg atcgcaaaag ttctgcgatt gtccacttgt tgctttaatt
    39301 ttggattatt cataacctaa ctccatttct tccattcaat tatttatatt ttctctaggc
    39361 acagattgtc cgatctctta aagaaagaca atttcatata gggctgtgac aaaagccgtg
    39421 tagcagtctc tttttccgag taaacggcgt tctagagaca gcctatcagc aataagccca
    39481 cccaagccaa aaatacgaaa agctgttttt gcttggctgc tcttattact taatgcagga
    39541 tagctttttc acaacctttg tcaactacta caactgaatc agtatagcat ggattcagcg
    39601 aatgaaaaag ccaccaaacc ataagagtca aatatttttt tgtcagctga ctaaaagaaa
    39661 agacgtgttg cttgtttatt caagcaacac gtctttcata accaagtttc caattatctt
    39721 cttggctcgt catcttcgaa ttcttttctg aagtatcttc gttcttcttc aggttccgct
    39781 tctgtttctt ccggatcatg aaaaatgaca cggattttaa ggattcgaga accttccatt
    39841 tcttcagaaa ccagcgtaat attatcgaca tcaaacgata acttttcgcc ttcatccgga
    39901 atcatgccta atgctgtaat caaataacca gccatcgtat ctacatcact catatgcaga
    39961 tcactgtcaa aagcttcatt gaactcatca atcagcatac gtccttggat gatatattcg
    40021 tgttcatcga ttttttcata aagattctca acttcatctg attcatcatc gatttctccg
    40081 acgatttctt ctaaaaggtc ttctagtgtt gctaacccaa cgacgccgcc atattcatct
    40141 aataaaatag ccatctgatt ctgcgtcttt ttcatttcat ataacagatc atcaataaag
    40201 accgtttcag gaacgaataa aggctcctgc atgattttct tgatatctaa attatcaaag
    40261 ccgaatttat gggcagcttt tagtaaattc tttgtatgaa ggattccgac tactttatct
    40321 ttgtcttcgt tataaacagg gattcttgaa tagttttcgg ataaaacttc attcacattt
    40381 tcttccacag tgtcgttgat atcaatcata aatgcatccg ttcgtgggac catgacttct
    40441 cgggcaactt tcgtatcaag agaaaaaacc ccttggagca tttctaattc ttcattattc
    40501 aatacgcctt cgttttcaag catataacgc atttcatctc tggtcatttt tgaatcttca
    40561 tcatcaaaag tcatcggcgt gatacgcgcc aataaacttg tggaagcaga aagcagccag
    40621 acgaagggct tagctactac accaatcaag cgtatcagcc ctgaagtgaa ctttgcgact
    40681 tcttctgatt tatttaaagc aatacgttta gggtacaatt ctccaaaaac aatcgataca
    40741 taggtcaaaa tagccagcac aatgatattt gcaatatttt ttgccgctgt gccgccacct
    40801 aataccggag ctaaccgttc cgataaagta ttagctagtg aagcaccaga caaaatgttg
    40861 accaaagtga ttcctacttg gattgtcgat aggaaattat ttggattctg caatattttt
    40921 aaaagctttt gagatttcac atctccttca tcagcttttt gctcgattcg attcttattg
    40981 atcgaaacaa cagcaatttc ggaagctgct aaaaaagcat tgatcaatgt caaaacgatc
    41041 aataataaaa tctgcgctaa cagcgactga ctctcagggt cagcattcat aatcgcattc
    41101 tctccttata aaattaattt ttagtttacg atagaaaaaa acgtggcact atagccacgt
    41161 taaaatggta tcacaaagca attttctttg caataaaaac aagtgtacta aaactaccta
    41221 cgaggtcgta gcaattttct tcttgttttc attttgcttg tcttctttga cgattttgat
    41281 tatataggaa atgatcgtct tgcagattgc gtaaaaagga acacctaaga agataccaag
    41341 caatccggca atatttccag ctactagaag aacgataatg atcgttaatg gatggatttt
    41401 cagtgatttc ccaattacat taggataaat gatattccca tccaactgtt ggacgattag
    41461 cacaaccaca caacaaagta atgcttttac cggatcattg aagactgtta ctagaaatgc
    41521 aggtgctagt cctagataag gtcctaaata tggaattagg tttgtcaatc ccgcaatgac
    41581 cccaaataag aaagcataat ccacaccaat taccatatat cctaaaaatg tgaaggtacc
    41641 aacgaataaa cattcgattg cttgtccgct aatgtaatta gccaatgttt tattcagttg
    41701 ccccaataac tccacaattt ggtttcttct tttttctggg aaaaactgtt ggatgtttgg
    41761 cactagtttt tctccgtctt tcaacatata gaacaagatg aatggtgctg taatgattac
    41821 tacggttgcc gaagcgatcg ttccaacgat cgaacctaaa ctattggata ctccactaag
    41881 gaattgctga atgattgtcc cgtaagaaat gtctaattgc tcaaaatatt tattgatatc
    41941 tacttccttg aacaaaggca attcggctac ctcttttaac cagctttcta cctgtttgat
    42001 gaaatcaggc atattagatg ccaatgagga aatttgctgt actagacttg ggatgacact
    42061 aagtaaaatc caaataattg ctgcaactaa aaggagcagc acaattgcga cagcccatat
    42121 tcttttgatt tttgctttca tcaacagctt gacaatagga ttcaataaat agtaaagaaa
    42181 gcctgcaatc agtacaggtg caaataacgt ggaaaaaaat gtcccgatcg gttcgaaaat
    42241 aaagtttatt tctgatgaaa tcatgatcaa tgcagctatg atcaataatt caagcgacca
    42301 aaacattagt ttagactgtc taagtttttc aaacaataga tttcctcctt tctttcttac
    42361 tagtatatat tatattcgtt aaaaattctt ttattctttt tttatttttg aaaacttgcc
    42421 atacttttta tttgttttat tttccagtat actatacgaa aggaaggtgg ctagaccatg
    42481 aaagttgtac aaacaaaaga tacaatgagc aatatttact tagatgctgt acggatcagg
    42541 catcaagttt ttgtagtcga acagggtgtg cctttgtctc gagaaataga caaagatgaa
    42601 gcccattgta tccacttcgt cctgtactca gataaaaaag aaccgcaagg aactgtacgt
    42661 cttttgcctt tagaaaacgg aaaaatgaaa ttacagcgga tggcgattct ttctgaatac
    42721 agacaccaag ggttaggaaa aatattgatt gaagaagcag aaaactttgc taagaatcaa
    42781 ggctataata cgattttatt aggggcacag tccacagctg aaacttttta cgaaaaacta
    42841 ggatatacag cttacggcga tccttttgaa gatgctggca tgcctcatat ttatatgaaa
    42901 aagactttat aaaaatttat ttcgaaaaaa gcaaaaaaca gcaagctttt gagaaaaatc
    42961 tctcactggc ttactgttct tttttgtgtt tacttacgcg acaattgctt gtaacggtta
    43021 taccaaatat caatatagcc ttccgagaac gggccatctc cattattgat ccagtcaacc
    43081 agaatcttca cattttcttt taggatgaag tcaatatcgt tcgggtaatt catcattttg
    43141 ctgtgcatct catattcatc gacatccaat agtcgtttct cgccgtcagg aaataccttg
    43201 atatccaagt catagtcgat atatttcaag gcctcatcgt ccagcaaaaa aggtgaagct
    43261 agattacaat aataggaaac ccccttttct ctgatcattg ctattacatt gaaccagtat
    43321 tttttatgaa aataaacaat cgctggttcg cgcgttaccc atcggcgtcc atcagattca
    43381 gtgactaatg tgtgatcatt cacgccgatc atagagtgtt cgcttgtttt taataccatg
    43441 gtatctcgcc acgttcgatg caatttgccg tcgtgcttgt aactttggat cgtcacaaac
    43501 tctccttctt ttggaactcc catagcaacc cttccttaag cagcattttg tgctttgtgt
    43561 ttgggtgttc attacaccga catcataatt attatatcaa taaaaatgag ctttgcctag
    43621 aaaggattcc tattgtttcg atttttctct aactgatcta ccagtttcat ttggacctta
    43681 ggaaaaacga ccgaatcaaa tgcatcaggc ttcaaccact tcgaagtttt gttctcggta
    43741 aattcttgtt ctgctccctc ggttgcccgt ccgtaaaaaa ggagaacatg ccatttcaga
    43801 tgactaaaaa tatgagtaac ttctcctaaa tgtcgtgtct gccaaacaaa gagttcctgc
    43861 ttttcaaatg ggagattttg ctcttcttct gctactaggt catcaaacag atcgatttct
    43921 ggctttgttt cccattcttt tttcaatcgc tcatactcct cttgtgtcac ttccatcatt
    43981 ggaaatgtcc acatattcgc cagcaatttt tggctatctc tttcttcaaa ataatacgct
    44041 ccagaatgat tttgaagagc tgcactgata taataaacgt cttttggctt tgcttttttt
    44101 gtttttacag gaaaactcgt ttggattcct cgtttgttag ctaaacaaaa ggcttggatc
    44161 ggacaagtct cacactttgg agaagttggt gtacagatag ctgaacctag atccatcatt
    44221 gcttggttga attcacctgg atgcttttca tcaatgattt tccgcatcgc ttcatcaaag
    44281 attttcctgc tagaagcttt tgcgatgtct gcttcaatgc aaaacaatct gctgactact
    44341 cgcatcacgt tgccgtcaac tgcaggttct ggaagtccaa atgcgatact tgcaatcgcg
    44401 cctgtcgtat atggtcctat tcccttcaat gagctaattt cttcaggcgt ttgcggcatt
    44461 tccccatcaa attctgacat gatctgttta gcagcagctt ggatgttccg ggctcttgag
    44521 taataaccaa ggccctccca tgcttttaaa agcttttctt ctggagcatt tgctagctct
    44581 tcaattgtag gaaaccattc catgaaacga taaaaataat cgatcactgt gtctactctg
    44641 gtttgctgaa gcatgatctc agagatccag atacgataag gatcacgatt atagcgccaa
    44701 ggcaggtttc ttttttcttg ttcataccat tgaatgaact gatcttgaaa ttcttttgtt
    44761 tctttatctg tccatttttc ccattcttta ttcactttcc tcttcctttt ccgtaatgaa
    44821 tcgctggatc atatccaaat caaatccttt ttgatataag ctttgcttta cttttagatt
    44881 tcttttttta ggttcaaacc ttaaatttct tcgccatagt ttatctcctt gtttgactaa
    44941 ataatcatat tctatttctt gatctgcttc ttgcggaaga tcagctatcg cttgttggat
    45001 cacttcttga gaaaagcctt tcgtcatcaa tgtttgttgg atttttctca ataattcttt
    45061 ttggcttttt ccgtgatttt ttccaaacgc tttttcggct gtctgatgtg cattttgaac
    45121 ttggtcttca aatgtatatt ggctgagcgc ttgttcaatg atttcaggtt tcaaaccttt
    45181 ttgctgcatc tgctgcgcta atttctttgg tcctttgtca cttaagcgca tattcgtgcg
    45241 cacataactt tccccataga ccaaatcatc gacaaggtcc aattctttta agcgggctac
    45301 gattttattt cgatcttctt gaaggatttc cttttctttt aagtatgttc ggatttcttt
    45361 ttccgatcgc aactgataac ttaagtaatt cattgctagg tgaaaaccga aatcagctcc
    45421 gctactcttc ttgatctctt ggatagtttc ttcgtctaat tcccgtcctt ttaataatcg
    45481 atagcgtact aatacatctt cagatacttg taaagcttct ccttcagata aatctacgcg
    45541 atagaaaggg cctttgcctt tactgattct cgtaacggtt aacataaaca tcctcctcga
    45601 acatatattc tctatcatac cacagaaaat ccccgtaatc aggtattata tgttagaata
    45661 aaccacagaa aaaagaaaaa gggagatact tatggcagaa acaattgtca aaactggaca
    45721 aacggttcct ttgaaaatca agcgtttagg cataaatggt gaaggaatcg gttatttcaa
    45781 acggttgatc atatttgttc catatgcact accaaaagaa gaagtactag tgaaaatcac
    45841 gaaagcaact cctcgctatg cagaaggaga attaataaaa gtcaaaaaaa caagcaaaga
    45901 tcgcgtagtg gcaccatgtc ctgtttacta tgaatgcggt ggctgtcaat tacaacactt
    45961 agcttatcaa gctcaattgg attttaaaaa ggatctgctt ttgcaagcat tggaaaaatt
    46021 caaaccagca ggctttcgat cttatcaact tttgccgacg atcgggatgg atgagccttg
    46081 gcattataga aacaaagcac aatttcagtt acgaaaaaat aagcagactc aaaaaattga
    46141 agctggttta tacgaagcaa actctcatca gttagtccct ataacagact gcttggttca
    46201 agaacctcga acacaaaaag taatgaatac tgttgttcaa ctattgaata aatttgatgc
    46261 acccatctat gatgaacgga caaacagtgg aatcttccgc acaatcatgg ttagaatcgg
    46321 tgttaaaact ggggagttac aagttgtttt tattactcgc agtaaaaaat tcccgcaaaa
    46381 aaacgcaatg atccgtgaga tcaatgaacg actgcccgaa gttgtttcaa tcatgcaaaa
    46441 tgtccaggca caaaaaacgt ctctcgtgat gggggatgaa acgatccact tatggggaaa
    46501 agaagccatt gaagaacaaa tcaatgaagt gactttcgat ctttctcctc gtgccttctt
    46561 tcaactcaat cctcagcaga ccgaattgct ttatggcgaa ggaatcaaag cattagatgt
    46621 ccagcctaat gaaacgatcg tggatgctta ttgcggagtt gggacgatcg gcttaagtgt
    46681 agcaaaacaa gccaaagaag tacggggaat ggataccgtt cctcaagcaa tcgctgatgc
    46741 aaaaaaaaat gcggaaagat taggatatca caacactcga tatgaagtcg ggacagcaga
    46801 gcaagttctg cctaaatggt tgaatgaagg ttttcagcct gatggtatca tcgtagatcc
    46861 accacgtacg ggtttggata acgcattgat ccaatcatta ttgaaatacc ctccaaaaaa
    46921 acttgtttat atctcctgta atgtttctac acttgccaga gatctggtta atttaagtaa
    46981 aaagttcaag attgaatatt tacagtccgt cgacatgttt cctcagactg cacgttgtga
    47041 agttgtcgtg aagatgacga gactcgctga ctaaatgaaa gaggttgtga aaaagtctgc
    47101 cctgtatcaa gtaataagaa cagccaaaca aaaatagctc ttcatgtttt atgaatactg
    47161 tacttgtgac cgaagagtta acaggaggac actatttatt taaaaaaagg gttgtgacat
    47221 agtttttgtc acagcccttt ttgattatta ttggatattc acgtctatca cttgataaaa
    47281 tgcatttgtc gtatcgctga tattccatac tgctaaaatc acattatatc cttttcgatc
    47341 ctgcggaagt gtgatcgttt ggttgactgt ttttggtgga acagttgctt tgtcgtctat
    47401 ttttgtgatc aattcaaaat cactaaattt caaaggttga ttaggattcc aagttggttt
    47461 ggtaatgtag taatcccaag tacttgtccg atgttgtgct gttaaattcc aagtaatatt
    47521 taatgttcct ggattaacca tgtttttatg ccatctgtta gatgtctgtt catctaaagg
    47581 ctcaaagccg ctgactcctg cactagcaat ttttccatca atgaatgtat ttttggtagc
    47641 ttcgatactt tgcggttccc attgtgctct tccgacattt tgatttaagt ttcctgctgc
    47701 tgatgttcct aggtatgcac ggcttcctgg agaagtaata taaccatgcg caaaacctgg
    47761 aatgctaaaa ccgaacaacc ctaaactaac taacccaata aacaataacg tactaatctt
    47821 tttcatgtag aaacctcctt catttgataa ccacattgta aacgctttat tgtattaaca
    47881 caaacattat gcttttataa ttttatgttg aagtaaaaaa ggtgaaaaaa gtaagatgca
    47941 gattataaca gaagtagacg agaaaagtac aaatagaaaa catgagaatc aaatcatatg
    48001 atctttttca aaaacatcat tcatataaac aaatgttcaa ctttttaata acaacaatta
    48061 tcaatttttt tcttacttca caaactaaat acaggtcttg ctgtgagcct tcatggtaaa
    48121 ctaatattat agaaaggagt tagtaaaatg aagatgataa aagatattcg tttttgggtt
    48181 tgtgttatag gaattgtcat attaggcttt ttatcagggt tgcttagcgg aaatcccgga
    48241 aaatattact attctttgca acttccacca tttgcaccac ctagctggat atttgggccg
    48301 atgtggacct tactgtatat attgatgggt atttctcttt atttgttact taatcacaac
    48361 aacaaaaaac agcgaaacaa tcttgtcggt ctttttgtga ttcagttcat ttttaatttt
    48421 atatggtctg ctctattttt taatttaaga aatattttca ttgcagcaat cgatattaca
    48481 cttttagtta ttttcttgtc agtgcttatg tatcagttgt ggctgcatca tcgcctggca
    48541 atgtggctca tgattcctta ttatttatgg gtactattcg caactctatt gaattattca
    48601 atttattttt taaactaagc gctaaaaaga gacgtcctgt aatttaacac atagaaaaag
    48661 tgccacctaa gttagatttt ttgtctaatt taggtggcac tctttattaa ccaaactatt
    48721 tttttctagt acccacttgt tgttccatac tcattattct ggtcataacc ataaccattt
    48781 tgttcctgtc cagcgtaagg atcataactt tgagtatctt gacttggtgt atagtactga
    48841 cttgtatctt ctgtttgctg ataataggta ttcggatctt ggtactgatc atatgtgttt
    48901 tctgaatagg aagaataatc ggtgtaccct tcactattcg atccatcacc gtttgtcgaa
    48961 tcgccatctt ccgaatcatc aaagaacatc attgaagcat tctcattttt caaattaggt
    49021 aatgtatcgc ttgtttttat atttaattgt ttcttcagtt cattttggat cgaaagaaga
    49081 tcattttttc ctaaaatttg atagtagata tcattgatca tttgtccttc gccttgcaac
    49141 tggtcttgtt tgattgtttc aaacgccggg gtgtagttcg tcgctacatc aagcatgtca
    49201 tcccaatcta agtccgtcgt cacattgttc tcaactgctt ttaaaaattt tctataattg
    49261 cttacgccat ctaaacttaa aactttattg acgattttcg tcactacttc ccgctgacga
    49321 cgttgtcgac cgatatcgcc ttctggatct tcgtgtcgca ttcgagaata ggctaaacct
    49381 ttttctccat tcaatgtttg ttcacctact ggtacatgga caccatccaa agtaaagtca
    49441 attttattat tcactttgat gccaccgacc gcattgatca aatcttccat gccatccaaa
    49501 ttgatcgtta cataatgatc aataggaata tcgagcagtt gctcaattga atccatggcc
    49561 atttcgacac caccaaatgc gtaggcatga tttaatttat ctaccgttcc ataacctacg
    49621 atattcgtat aaatatctcg gtccaaactg atgatcgttg attttttttg tttcggatta
    49681 actgttacta ccatcatcgt atcagaacgt ccttgttccg ttcttcctaa tccaccggta
    49741 tctaaaccta atagcaaaac cgaaaaaggt tctttgtcat caatgcttac tctctcagaa
    49801 cgtttggagg atattcgatt agagttttta gaaattttgt ttactgtttg gctcgcttct
    49861 cccataaatc tgattccgta tgctgataat ccggcaatca gcaaaacgaa tacccctaac
    49921 aaggttaata gaactttttg ccatcgcttc ataatacacc tctgtttcac attttctaaa
    49981 atattgtctc atataactgt tcaatcagca aattcacttt ttaatcataa gaaaacttta
    50041 aaaaacattt ttgtgtaacg attattattt tttaaaattt ctcaaaattc ttaactatca
    50101 taccataccg tgaaaaagat cgaaagaccg aatacacgca gttcgcaatc gttttatctt
    50161 tttttatgta ttttttccag aaaaagcgaa caacaaggta ttttccaaat aatcgtgcag
    50221 taaaatgatc gcacatacct ttcccatctt tttaacagtc tttgcctacc gttcagatta
    50281 tcattcgatt tcacgacaat ttcttcctat gactggtcct tttgttaaac ccatcttcta
    50341 ttcgttttat ttccagctca ctgcatggct cttaaaatga ctcgaactag tgattgcatt
    50401 accatcatct tttaatggat agatatgctc ctcttcaaag taaaacgatt ttcttttaaa
    50461 gtaatagaat tgacatggta atgagtatgt atactagtgg tttcacaaat ggtcttttat
    50521 tcaacatcca aaaactgaaa tttctttaaa atccattact aacgaagaaa atgttccttg
    50581 cttgataatt agttaggaca tgtcaagtga acaaatgcat ttacttagcc aaaaaatcta
    50641 aaaacttcat aaatagacaa aaagacacga ctctctaaga agtcgtgtct ttattcaaca
    50701 aattattata atttagtcac ttcagcagct tgaggtccgc gtgcaccttc aacaatcgtg
    50761 aattctactt cttgaccttc ttctaggctc ttgaagccgt ctccttgaat tgctgagaaa
    50821 tgaacaaata cgtcatctcc gccgtctact gtaataaacc caaatccttt ttcattgttg
    50881 aaccatttaa ccgttccgtg ttccataaat gtatatcctc caaaaaagtt cttgcaagta
    50941 accttgcaag aacattatac ccaatttaga aaacgctagc aagctttcgc tcttttattt
    51001 tccaaattat ttttaagact gatatgacgg aggaaatggt tattttgctg cttcgaaacg
    51061 tttgtttact tcatcccaat taataacatt ccagaatgct gcaatataat ctggtcggac
    51121 atttttatat ttcaaataat aagcatgttc ccaaacgtcc aaacctagaa ttggtgtctt
    51181 tccttccatc aatggagaat cttgatttgc agtagaggta atagctaatt ttccattttc
    51241 cattacaagc caagcccatc cagaaccaaa tcgtccagcg gctgcttttt tgaattcttc
    51301 tttaaaagaa gaaaaatcac caaaagcttc attaatcgct tcttttattt ctcctgtagg
    51361 ttcgccacca gcatttggtg ccatgatttc ccagaaaaat gaatggttag catgtccgcc
    51421 accattgtta cgtacagctg tcttgatatc tgttggaata gcgtccatat cagataataa
    51481 ttcttctatt gttttttcgc ctaattctgg gtatttctca attgctgaat ttaaattcgt
    51541 cacataagta ttgtgatgct tatcatgatg cagatgcatc gtttcttcgt caatataagg
    51601 ttccaatgcg tcatatgcat aaggtagatc tggtaatgtg taagtcataa aaaaattcct
    51661 cctcaatgtt ttcttaataa tgtctacatt acaaagagta acaaagagaa ggaaattctt
    51721 caattgttat gcctagtcgt ctttttcact ttgacctact tcttcttcaa aaacctcagt
    51781 ttctttaaaa ataaacaact tgctgaaaat atagttcgca aggataacaa taatttgagt
    51841 gatgattttc gccacatact cattgctgtt cataacattg atcaacaata ccattgcccc
    51901 catgtccaat ccgtaagaaa ggatacggta gaagaagaac ttaccgcatt caataagtgc
    51961 atgtgtaaaa ttcggtgatt ttgaatggaa tacccaaagt ttgttcgtta caaaagcaaa
    52021 caatacagaa caaaaccacg aaatagaatt ggataaggcc atacttaaat caaaatattg
    52081 gcgtgcgaga gcaaaactaa caaaatttac aatcgtagcc aaaccaccaa aaaagagata
    52141 gactagtatc tcccaatatc cttttgcttc taaatatcct tttaactgtc gatactgctt
    52201 catgagccaa cctaccttat taaaaattct tatttatcat actctatatt tcaataactt
    52261 tcatctttat ttaaaaaaat taattttttt tgatcctttg cctttgtctc tgcttggatc
    52321 gtcacatgtg taataccata ttttaatttt aataaagaaa ttatacgagg atatatcttt
    52381 tcaatctcgc ttagtagctg atcttcaaaa tcaatatgtc cgtcgaaaat aattatcttt
    52441 tcgctatact gccaaatatg gacatgatga acatccttta ccccatcgat tgcttcaatt
    52501 tcttgttcca ttttttcata gtcgatagca ggtgcacttt gtatcaaaat agcggcagct
    52561 tttttgatca ccattatcgc ttctatcaat atatatatcg aaatgatcag tgtaataact
    52621 ggatcgatcc agtagatatc gaaaaaacgg atcaaaattg ctccgataat cacacttacc
    52681 gaagacagtg tatcacttaa caaatgcaaa taactagatt ttatattcaa actttcatct
    52741 gcttcttgtc gtaataataa tactgagaac aaattcgcga gcaatccaat aactgctact
    52801 gttagcatca aatgactatt tatcttttct ggtgaagtga accgcttgaa tgcttcaacg
    52861 gttaaaaaca aggataatat gatcaatatg aatgagttga tgaaagcact caatatttct
    52921 aaacgctggt agccatacgt acgtttttta tttgcttctt ttcgggccat tttttgtgcc
    52981 ccgtaagaaa aaataattgc caatgtatca ctaaggttat ggaaagcatc tgaaacaaga
    53041 gacaaactcc ctgacataat ccctccaata aattctgata aagtgatcac cgcattcaaa
    53101 accactactc caaatagttt ttttgatgat ctctgtggct gtgtaggcac tattccttcc
    53161 tccattttat ttatattgga tagtctttag acaagaataa catttttttg atatttcacc
    53221 aatcattcag ctgtttcctt aaagcacttg tatttcactt gatacttcgc tagaattgca
    53281 agtgatgaca ctactagatg aggagtactt atgacaacaa aacaattaat tatcagttcc
    53341 tttatacgat tcaaagacct aaaggaggcg agaaatgtcc cattttggaa agccattgtc
    53401 tatcttttag ttttgagtat aattatggct ttgccaatct cttttcaagt ttttcaagtc
    53461 ttaaacaaca ttcaattgga tgggcaaaag attgctactc gcattcctga ttttacaatc
    53521 caaaacgggc agcttcaaac cgaagaaaaa gaaggattca tttaccaaac aaactccatt
    53581 atcttcacat ttgatccaga gggaaaacga acagaacagg acatctctac tgatttgatg
    53641 gggaattttg ttagtgtcgg gatgttaaaa aacaaactta tcatagctct tcctaataca
    53701 ggcacgactt ctgctttgtt gaacaataac caattagaac ttccctacac caatgaatct
    53761 ttaaaaaact taacaggtaa gcagctccgt tcttttttaa gtgaagcatc tataccactt
    53821 tggataaaag tcctgacatt tatattttct atttatccta gttttctgaa tctgctgatc
    53881 actttgctat ttaccaacat tgctgctttt ctctatgcac gctttcgact aacaaaagct
    53941 acttttcttg attgtttaaa aacattgatc tattcaattt cattgcctac tataattgca
    54001 acaatcttga tggtctttct tccttctttt gacactagcg ccttcattgc ttttgcagga
    54061 atctttattt ttgctcaagc tgtcaaagga tgggcaaaaa tatcgatcaa ttaagaaata
    54121 aagacaactc gttatttcta cttcaataga cccttttaga ggttgtgaca tttttttgtc
    54181 acagcccctt ttttatttga aaaatatttc tttctcaaaa aacaagcaag gcgcttcaaa
    54241 gttcttcttg tatgcgctac acttagagta aagaaaggcg ggaaattaac tatgtcagaa
    54301 agaatcattt atgcagatcg tccatttcgt gatgaattta tcgaagaaat ccatactata
    54361 gcgcctggtt atatctttaa aacagaatta caaccagagg atctacaaaa tgtagagatc
    54421 agtttgggct ggaactcaga ctaccaagaa aaactattag cctcttctac cttgaaatgg
    54481 gtccaatcta tctcagctgg tgttgatcag ctaccccttg agactttttc aaagaaacat
    54541 attttacttt caaatggtag tggcatccac agtgaatcga ttacggagca tgtcttagga
    54601 atcatccttg ggtattctcg tggtcttttt caagcacaaa aggcacagag tgacatgaaa
    54661 tggttaggtt catcggtcca ttaccaatct atccaaggga aaaaaatact aatcattgga
    54721 actggccata ttggaaaaat gattgcaaaa aaatgcaaag cattagacat gaactgctat
    54781 ggaatcaata catccggtca tccagcagaa ggaatggaaa agactttttc tttaaatcaa
    54841 ctaaaggaag ttcttcctga agtagatttc gtagtcaata tcttacctct aacggaggaa
    54901 acaactgggc tctttgatca gcatatgttt gaacactttg atccaaaatc tgtattcatc
    54961 aatgttggcc gtggtgcttc tgttaagaca caagatctgg tgcaggcttt aaataaccag
    55021 caactttcct ttgcagcatt agacgttttt gaggaagagc ctcttccaca agatcatcct
    55081 ctttggaaaa tggacaatgt actgattact tcccacattg caggtttgac acctgatttt
    55141 caaaagaaat taatggctat ttttttaacc aatctgaaaa gctactttgc cacccatgag
    55201 cttcaaacca atcaagtaaa attgtctgca ggatattaat agctgaaaac aatattttca
    55261 aaagaaaaaa
//
LOCUS       DAPBBV010000017        53767 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.017, whole genome shotgun sequence.
ACCESSION   DAPBBV010000017 DAPBBV010000000
VERSION     DAPBBV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53767
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.017"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            7..729
                     /locus_tag="RD486_001233"
     CDS             7..729
                     /locus_tag="RD486_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7662976.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            787..2826
                     /locus_tag="RD486_001234"
     CDS             787..2826
                     /locus_tag="RD486_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HDT7662977.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2935..4086)
                     /locus_tag="RD486_001235"
     CDS             complement(2935..4086)
                     /locus_tag="RD486_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDT7662978.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4240..4770)
                     /locus_tag="RD486_001236"
     CDS             complement(4240..4770)
                     /locus_tag="RD486_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDT7662979.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4869..5219)
                     /locus_tag="RD486_001237"
     CDS             complement(4869..5219)
                     /locus_tag="RD486_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HDT7662980.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5376..6905)
                     /gene="ahpF"
                     /locus_tag="RD486_001238"
     CDS             complement(5376..6905)
                     /gene="ahpF"
                     /locus_tag="RD486_001238"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDT7662981.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6915..7478)
                     /gene="ahpC"
                     /locus_tag="RD486_001239"
     CDS             complement(6915..7478)
                     /gene="ahpC"
                     /locus_tag="RD486_001239"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDT7662982.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7622..8284)
                     /locus_tag="RD486_001240"
     CDS             complement(7622..8284)
                     /locus_tag="RD486_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7662983.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8468..10114
                     /locus_tag="RD486_001241"
     CDS             8468..10114
                     /locus_tag="RD486_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDT7662984.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10105..11187
                     /gene="uxuA"
                     /locus_tag="RD486_001242"
     CDS             10105..11187
                     /gene="uxuA"
                     /locus_tag="RD486_001242"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7662985.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11295..12848)
                     /locus_tag="RD486_001243"
     CDS             complement(11295..12848)
                     /locus_tag="RD486_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7662986.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            12996..14284
                     /locus_tag="RD486_001244"
                     /pseudo
     CDS             12996..14284
                     /locus_tag="RD486_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(14410..15489)
                     /locus_tag="RD486_001245"
     CDS             complement(14410..15489)
                     /locus_tag="RD486_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7662987.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15592..16032)
                     /locus_tag="RD486_001246"
     CDS             complement(15592..16032)
                     /locus_tag="RD486_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7662988.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(16089..16499)
                     /locus_tag="RD486_001247"
     CDS             complement(16089..16499)
                     /locus_tag="RD486_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDT7662989.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16679..17113)
                     /locus_tag="RD486_001248"
     CDS             complement(16679..17113)
                     /locus_tag="RD486_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7662990.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(17213..18061)
                     /locus_tag="RD486_001249"
     CDS             complement(17213..18061)
                     /locus_tag="RD486_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7662991.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            18450..20216
                     /locus_tag="RD486_001250"
     CDS             18450..20216
                     /locus_tag="RD486_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDT7662992.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            20318..21577
                     /locus_tag="RD486_001251"
     CDS             20318..21577
                     /locus_tag="RD486_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7662993.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            21724..23025
                     /locus_tag="RD486_001252"
     CDS             21724..23025
                     /locus_tag="RD486_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7662994.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            23028..23879
                     /locus_tag="RD486_001253"
     CDS             23028..23879
                     /locus_tag="RD486_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7662995.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            23892..24707
                     /locus_tag="RD486_001254"
     CDS             23892..24707
                     /locus_tag="RD486_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HDT7662996.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            24858..26024
                     /locus_tag="RD486_001255"
     CDS             24858..26024
                     /locus_tag="RD486_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7662997.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            26254..26901
                     /locus_tag="RD486_001256"
     CDS             26254..26901
                     /locus_tag="RD486_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDT7662998.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            26985..27929
                     /locus_tag="RD486_001257"
     CDS             26985..27929
                     /locus_tag="RD486_001257"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HDT7662999.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGTEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            28064..29515
                     /locus_tag="RD486_001258"
     CDS             28064..29515
                     /locus_tag="RD486_001258"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HDT7663000.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            29536..30372
                     /locus_tag="RD486_001259"
     CDS             29536..30372
                     /locus_tag="RD486_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDT7663001.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            30372..31031
                     /locus_tag="RD486_001260"
     CDS             30372..31031
                     /locus_tag="RD486_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7663002.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            31157..31846
                     /locus_tag="RD486_001261"
     CDS             31157..31846
                     /locus_tag="RD486_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663003.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            31852..32808
                     /locus_tag="RD486_001262"
     CDS             31852..32808
                     /locus_tag="RD486_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HDT7663004.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            32852..33364
                     /locus_tag="RD486_001263"
     CDS             32852..33364
                     /locus_tag="RD486_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7663005.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(33620..34168)
                     /locus_tag="RD486_001264"
     CDS             complement(33620..34168)
                     /locus_tag="RD486_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7663006.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(34257..35437)
                     /locus_tag="RD486_001265"
                     /pseudo
     CDS             complement(34257..35437)
                     /locus_tag="RD486_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
     gene            complement(35673..37181)
                     /locus_tag="RD486_001266"
     CDS             complement(35673..37181)
                     /locus_tag="RD486_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDT7663007.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            37340..37531
                     /locus_tag="RD486_001267"
     CDS             37340..37531
                     /locus_tag="RD486_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663008.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            37734..38651
                     /locus_tag="RD486_001268"
     CDS             37734..38651
                     /locus_tag="RD486_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HDT7663009.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            38644..39717
                     /locus_tag="RD486_001269"
     CDS             38644..39717
                     /locus_tag="RD486_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663010.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            39865..40383
                     /locus_tag="RD486_001270"
     CDS             39865..40383
                     /locus_tag="RD486_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663011.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            40364..40756
                     /locus_tag="RD486_001271"
     CDS             40364..40756
                     /locus_tag="RD486_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HDT7663012.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            40832..41767
                     /locus_tag="RD486_001272"
     CDS             40832..41767
                     /locus_tag="RD486_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HDT7663013.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            41900..42679
                     /locus_tag="RD486_001273"
     CDS             41900..42679
                     /locus_tag="RD486_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDT7663014.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            42672..42989
                     /locus_tag="RD486_001274"
     CDS             42672..42989
                     /locus_tag="RD486_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDT7663015.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            43233..44843
                     /locus_tag="RD486_001275"
     CDS             43233..44843
                     /locus_tag="RD486_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7663016.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            45000..45848
                     /locus_tag="RD486_001276"
     CDS             45000..45848
                     /locus_tag="RD486_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7663017.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            46079..46558
                     /locus_tag="RD486_001277"
     CDS             46079..46558
                     /locus_tag="RD486_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663018.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            46591..48819
                     /locus_tag="RD486_001278"
     CDS             46591..48819
                     /locus_tag="RD486_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7663019.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLIISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            48948..50591
                     /locus_tag="RD486_001279"
     CDS             48948..50591
                     /locus_tag="RD486_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDT7663020.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(50664..51209)
                     /locus_tag="RD486_001280"
     CDS             complement(50664..51209)
                     /locus_tag="RD486_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HDT7663021.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(51232..51717)
                     /locus_tag="RD486_001281"
     CDS             complement(51232..51717)
                     /locus_tag="RD486_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7663022.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(51707..52519)
                     /locus_tag="RD486_001282"
     CDS             complement(51707..52519)
                     /locus_tag="RD486_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HDT7663023.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(52658..>53767)
                     /locus_tag="RD486_001283"
     CDS             complement(52658..>53767)
                     /locus_tag="RD486_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HDT7663024.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        17904 a         9781 c        10381 g        15701 t
ORIGIN      
        1 tctattttgt tactgcttac attagtagtt ggctattttt cgattgagtt tatccatgga
       61 ttttcgtctg caaaacagag ttcaactgtg aaaaaggtag agccgaaaag tatccctacc
      121 acactaaatg tggctttgat tggttcagat gctcgttcga aagacgaaaa cggtcgctcg
      181 gattcacttc tggttgcaca atacaaccag aaaacacaac aagcaaaact gatctctatc
      241 atgagagatt catatgtcga tattccaggt tacggaatga ataagataaa tgcagcttac
      301 tcttatgggg gagttgattt attaaatcaa acattaaagg aaaatttcaa atttgaagct
      361 ccctattatg caagtatcac atttcaagat tttatcgatt gcgttaatga actgtttcct
      421 ggtggagtca agatcgatgc agaaaaatct ctagatttag atggcgtata tataaacaaa
      481 ggagagcaag tgatggatgg taatacttta ctccagtatg ctcgatttcg ggaagacaaa
      541 gaaggagact tcgggaggat cagaaggcag cagcaagtga tcaaagctat ctctcagcag
      601 ctgaaagacg taacttcaat attcaagcta cccaaagcgg ttgggaaatt acttggtagt
      661 atccaaacga accttccaga aagtgtgctt ctggattgtg gtatggattt cctcaaagac
      721 atatgttaga ataaacaggt ataaatagtg aaataaagga atgacaagca agagaaggag
      781 gaaaaaatga aaagaagtga caagcacggc aaaaatcgaa caggcgctta tattgccggc
      841 gcagtgatct taatagcagc tgcgggtggc ggttattttt actaccagca ctatcaagaa
      901 acccaagcag tagaagctgg agaaaagaca gttgagcaat ttgtccaagc tttgaacaag
      961 ggagattata acaaagctgc agaaatgaca tcaaaaaagg cggcaaataa aagtgcatta
     1021 tctgaaaaag agatcttaga taaataccag aatatatacg gtgctgctga tgtcaaagga
     1081 cttcagatat cgaatctaaa agtagataaa aaagacgatt ctacttacag tttttcatat
     1141 aaagcaaaga tgaatacctc attaggtgaa ttgaaagatc tttcttataa aggaacatta
     1201 gacagaaatg atggtcaaac cacgatcaac tggcaaccca acttggtttt tccagaaatg
     1261 gaaggaaatg acaaagtaag cctgaccaca caagaagcag caagagggaa tattatagat
     1321 cgaaatggtg aaccattagc aacaacaggc aaactaaaac aattaggagt cgttccaagt
     1381 aaacttggag atggaggcga aaaaacagcc aatatcaaag cgattgcttc ctccttcgac
     1441 ttaacagaag atgctatcaa tcaggcgatt tcacaaagct gggtacaacc cgattacttt
     1501 gtcccattga aaatcattga tggagcaacg ccagaacttc cagctggagc taccattcaa
     1561 gaagtagacg gcagatatta tcctttgggt gaagcagctg ctcagctgat tggttacgtg
     1621 ggagatatca cagcagaaga tattgataag aatccagaat taagcagtaa tggaaaaatc
     1681 ggtcgctcag gtttggagat ggcttttgat aaggatcttc gtgggacaac aggtgggaaa
     1741 ttaagcatta cagatgcaga cggtgtagag aaaaaagttc tgatcgaaca tgaagttcaa
     1801 aatggcaaag atatcaaatt gacaatcgat gcgaaggcac aaaaaacagc ttttgacagt
     1861 ctaggaggaa aagctggatc aactgttgcg acaacgccaa aaaccggtga tcttcttgcg
     1921 cttgctagct ctccaagcta tgatccaaac aaaatgacaa acgggatctc acaagaagat
     1981 tacaaagctt atgaagaaaa tcctgaacat ccattcatca gccgatttgc gacaggttat
     2041 gctcctggat ctacgtttaa aataattaca gcagcaatcg gtctcgacaa cggcactatc
     2101 gatccaaatg aagtgttgac gatcaacggg cttaaatggc aaaaagacag ttcttgggga
     2161 tcttttcaaa caacgcgtgt cagtagtgat gtatcacaag tagacttaaa aactgctttg
     2221 atctattccg ataatatata tgcggcacaa gaaacgttga aaatgggtga gaaaaaattt
     2281 cgtacaggct tagataaatt catttttggt gaagaccttg atttgccaat tagtatgaat
     2341 ccagcacaaa tttctaatga agatagcttt aactcagata tcttgctagc tgatactgga
     2401 tatggacagg gcgaacttct aattaatcct atccagcaag cagcaatgta ttctgttttt
     2461 accaacaatg gaacacttgt ctatcctaaa ttgattgcag ataaagagac aaaagataag
     2521 aagaatgtca tcagcgaaac agcagtacaa acgatcgtgc cagatctgag agaagttgtg
     2581 caagatgtaa atggtacagc acattctctt tctgctttag ggattccgtt ggcagcgaaa
     2641 actggtacag cggaaatcaa agaaaaacag gatgtaaagg ggcaagagaa cagtttcttg
     2701 tttgctttca atcttgataa ccaaggttat atgatggtca gcatgttgga aaataaagaa
     2761 gatgatgatt cagcaaccaa acgagcatcg gaactattgc aatacctcaa ccaaaattat
     2821 caataaaaaa ttgcttttta agtacagtaa aaggactgtg gcgttatcgt cacagtcctt
     2881 ttttcaaata aacggttttc acgatgtctc tttcacaact tctttttgat ttactcacac
     2941 ttcataaact ttttttgtaa aatatttgag aacaagtgga gaaataagtg tacttaataa
     3001 aatcacgata actaaaggtg aatagtactg tggttcgatc aattgacttt gctgtccaat
     3061 ttgtaaaatg atcaaagcca tttctccacg cgaaatcata ccagcaccga ccatcaatga
     3121 actatgttga gaaaaaccgg caatctgagc accaaaataa cctccaagca atttggtcaa
     3181 aatcgctaca agcgtcaata tagaaataaa gagtagttgt tcactaaagt cagaaaaatc
     3241 aacttctaat cctacactga caaaaaatac tggtataaat actgcatatc ctaaagcctc
     3301 tacattgtgg tatacttctt ctttaacctt tgtctgactg acagctatcc cagcaaaaaa
     3361 agcaccaatg acagagctaa gcccaacaag atccgctacg taagacattc ctaaacaaat
     3421 aactagcgat acgatgataa tagaagaatt tgcgtacact ttttctgcaa atgaaagtag
     3481 gaaaggcgca atccatttga ctaataagaa aataaaaaca aaataaatta gctgttcaat
     3541 caaaacaagc ggtaaagaag cattgctaga agcttccccc gttagaaaag ataggctgaa
     3601 acttagaact aaaacgacta aaatgtcatc taccacagaa gcacccaaaa ttgttgatcc
     3661 ttcttttgta ttcactacgt ttagttcttt taatacttct actgaaatac tgacagaagt
     3721 tgccgcaaga ataatcccaa agaaaatcgc ttcatttccc gaaacttgga atgctttgcc
     3781 tgtcaaccag ccaaaaacaa ccgggaagat gatcccaagc aaagcaacga acataccagg
     3841 tcggaaatat tttttcaaaa gagataaatc actttccaga ccagctaaaa acattaataa
     3901 gatcacacca atctccgaaa agtcatggac tagaatatca ggtttgaccc aattcaatcc
     3961 agcttggcct agcaaaacac caacaagtaa ttgtccaatc actgctggga tacctaatct
     4021 ccgcgagata tgtgagccaa tcgttgttga aatcaatatc aggcataaaa taccaataaa
     4081 ttccattctc atcattcctt tgtataaaat atagcccgaa cttagcataa catacattat
     4141 tgaaaaaata ggaaaatata ctcacaaaaa aaccaacaat ccaaaagatt tttttggatt
     4201 gttggttttt atacggtcta ttttaataac taaaaatgat taacgtatag tcatttttct
     4261 tattctgatg aaattgataa tctcctggat gcccatgaaa atcaaaataa agccgaatat
     4321 ttggaataga agcatcaaac ttttgaatgg attgaacaat aagacgaatc cgccaatcaa
     4381 caacagaata ctactataaa cactccaact tttagctttt gtattcatgc tgaagaacaa
     4441 ctggaacaag ctgttgatga taacagctaa tccaagaaga atcggcagga tagaaacgat
     4501 tgcaggtgca aaagcataga cgatcagagc taagatcagg aaaaaaagac cactgaacag
     4561 accgatactc caagaacctg ttttcctttt aaaacggtaa gcctcaaaaa gattcaacaa
     4621 cccaagcaaa acaagatagg cggtgatcag ataaccgata aaatgaaaaa cagcagaagg
     4681 gtttagcaca atcgcaatcc cagaaataat ataaacagca gctcttaata aggcgtattt
     4741 ttgaatattt tgtttaatcg tctcaaacat ataagaaaac ctcctttgac ttattttaac
     4801 gtgaactagt cattttacca aattaaatgt tacaaaatga gcgaaggaga agaatatctc
     4861 tggaaaaatc aacttctgag gatcttttcc atttttttgc cttttgctag ctcatcgatc
     4921 attttatcta aataacgaat ttctttcatc aagttatcct cgatgtcttc tactcgtaca
     4981 ccacaaacaa cacctgtaat caaggaacgt gaaggattgg ggacaggggc ttccgcaaaa
     5041 aattgttcga aagtcacttg tttttgtagt tgatattcta gttctgtttg ggaataaccc
     5101 gtcagccaac aaatgatttc atctacttcc tcttttatac gatcttttct ctccgctttt
     5161 gctacataca taggataaac gcttgcaaaa cttgtcgtaa aaatacgatt ttgcgccata
     5221 atcagtcacc tttctttttt tcaaattatt tactacttat agtatataag aaaaagagaa
     5281 gaaaaagcga ttattcaaaa aaacaaaaag gattgtgaca aaattcttgt caccatcctt
     5341 ttttccgctc tctgactttt tacaatcttc atagctcaag tgcgcatcag ataatcgaat
     5401 gctcctaaag ctgcagtagc tcctgaaccc attgaaacaa tgatttgttt gtatggacta
     5461 tctgtacaat caccagctgc gaaaacgccg gggatattcg ttgcgccatt tttctcggtc
     5521 actatttcat ttcttggatt catttcgatc gttccatcta gccaatccgt attagggagt
     5581 aagccgacta gaatgaatac tcctgaaaca gctagtgtat gcatctccat cgtacggcga
     5641 tcgatatagg agagagattc tacctgattc gtaccgctga tttctttcgt cgctgcatgt
     5701 ttgataacag tgacattcgc aagagagact agtttatcct gtaagatttg atctgctttt
     5761 aattctggta agaattctag aacatataca tgttttgcta acccagccaa atcgattgct
     5821 gcttcaacac cagaattacc accaccgata acagcaatct cttttccttt aaataaaggg
     5881 ccgtcacagt gtgggcaata agcaattcct ttatttttaa actctttttc gcctggtaca
     5941 ttgatagaac gccagtgcgc acctgtcgcg atgatggcgg tttttgcttt aagtgatata
     6001 ccgttagcta agccaatatt aataaaatgt tgctctttat ttaaggaaac ggcctgttga
     6061 ttcatcataa tgtcgatagg gtaactacgc acatgacttt ctacttgctg catcaatttt
     6121 ggaccttctg tgtaagaggt accaatcata ttttcaatcc ctagtgtttc aacgacttgt
     6181 ccgccgaaag aatcagcgac aagtcctgta cggattcctt tacgtgctgc atagatagct
     6241 gcactactag ctgctggtcc accgccaatt actaatacat cataaggttc tttttcaaac
     6301 aactcttctt caatcaaagg gccagtgatt ttttcaacaa tttgttcgat cgtcatgcgt
     6361 ccgctactaa attcttctcc atttaaaaac acagttggca ctgccatgat ttttttatca
     6421 tcgatttctt tttggaacat cccaccttca atcatcgtat gagtaatatt tggatttaat
     6481 acagctaata tattcaatgc ctgtacaacg tcggggcaat tatgacaagt caagctaaca
     6541 taactgtcaa aatgcaatgt ttgtgttatt tttttgattt taagactcaa agattcactg
     6601 attttcggtg cccgtccact aatttgtaac atagccagta aaaaagagga aaattcatga
     6661 ccgaggggga taccagcaaa aacgattcca ctttctttgc caactggatt gatagaaaaa
     6721 ctaggtgtgc gcatcgaatc tcttttttcc caagagattt taggagacat ttctgctatt
     6781 tccttcgtaa attcagctag tttttgacta ttttcactat tatccaaact aacagaaaaa
     6841 acaataggag attcaatcag tgctaaatat tgttcgagat tttgtttagt ttctttgtct
     6901 aacatatcca ccacctaaat ctttccaaca agatcaaaac ttggtttcaa tgtttcgcca
     6961 ctttctttcc attttgccgg acaaacttca cctgggtggg tacgtacata ttgagcagcg
     7021 cgaatcttat caatcagtgc actagcgtca cgaccgattc catctgcatt gatttccata
     7081 gcttgaacga ttccgtctgg atcaataata aatgttcctc gctgagctaa tccttgctct
     7141 tcatccaaaa catcaaaaat acgagaaatc tgatgagacg gatcaccgat catcacgtat
     7201 tcgattttac cgatagcatc tgatgtatca tgccatgctt tgtgagtaaa gtgggtatcg
     7261 gtagagcaag aaaagacttc aacacctaaa gatttcaatg tactgtattg ttcttgtaag
     7321 tcttctaatt cagtaggaca aacaaaagta aaatcagctg gatagaagca aagaatactc
     7381 cagttcccca taagatcttt ttcactgact tctaaaaatt ctccttgatg ataagcatgt
     7441 gcattaaatt cttcgatttt tttcccaatc aatgacatag taaaacctcc aataataatt
     7501 atttatttat aattattgta atttagttgg agttgcaaag tcaatggata ttttgttatt
     7561 taataaagat tactcaaaaa cgaaggttaa ttataaaaat agaagaggtc gcaagaaaat
     7621 gctactgctg gaaatactcg ggataacgtt gagtaacagt ttcctgttct ttcagcatca
     7681 tgtgtaagtg caatcccgtt tgaaatcgag cttcttctgg ttttttatca actaaagcct
     7741 tgagtaaatc ataatgttgt tccatgatcg tttcccatgg aagcccctga atggtcactc
     7801 gtaaccagcg gaaacgttct aaatgggtat tatggtcatc taaccagttc caaacttctt
     7861 ttcttcctgc aatttcgaaa caagcttcat gaaataaatt atctgcacgg aaaaaagcgc
     7921 gttcgtcatt tattttgact gctttttctt gttcttctaa aatcgtttct agcactattc
     7981 gtgtttgtgt gtccaatttg gaacaacatt caatcatgat ttgctcttcc aactgttctc
     8041 ggacaaagcg agcattttct gcagaaacaa gattaatttt ggaaacatac gtaccacttt
     8101 gaggtatcgt atacacgagt tcttgctgac gtagttgaat caatgcttcg cgaatgggag
     8161 tccggccgat agcaagatgt tcctccagtg ccttttcaga tattttcctt ccaggttcta
     8221 agtcagcata gataatttgt ttacgaatcg cttgataagc ttgtgattgc aagctgcttt
     8281 tcatctttat tcctccaaaa tcatttctat gaacgtagta taacagaaga ggtctgaaaa
     8341 acaatctggt atgtcacatt aactagtaaa tttgtataaa tagtaaaatt ttggttgaca
     8401 tagcgatttt tattgtataa aattcacttg aatacaaaaa ctaatatgtt agtttaggag
     8461 gggaaaaatg attgatttaa acaactggag gaactttatc cctgaattat ctcaaaaaga
     8521 agtagaaata cctcattttg accgtgcatc attaagagaa aatggacaaa aaaatcctgt
     8581 ctggatccat ttcggtggcg gaaatcttta tcgaggattt catgcagaaa tcgctcaacg
     8641 tttagcggat ctaggcgaat tgtccactgg tgtcattgtt tgtgaaacat tcgatgaaga
     8701 aataattgaa agggcttacc aagattttga tgatttgatt cttgaagtgg tcatgccaag
     8761 cagtggagag ttcgtcaaac gtatattagc tgcgacagct gacagtctgt attgtcatcc
     8821 agattgttct gaacactttg ataagatgat tcgacacttt gaaaatccta gtttacaatt
     8881 agttactttt gctattactg aaaaaggtta tcgattgaaa gatacaaata ataaatatat
     8941 aggaccgatt gcagtcgata taaaaaatgg tccaaagaag ccatcacata caatgagtat
     9001 tcttgctgcg ctactttata aacgtttttt atctggagct tggccgattg cacttgtctc
     9061 tacagataat ttttcacaaa acggtagtca attacgtact tctttgctaa cgatcgcaaa
     9121 agaatggcaa aaggaaggtt atgtacaaaa tacatttatc caatacttat cgaatgaaga
     9181 aattgttgcg tttccatgga cgatgattga tcgtatcacc ccgaatcctt ccttgtcagt
     9241 tagcaaaatg ttggcaaaag agggcttttc aaatatgtcg attttccaaa ccgcaaaagg
     9301 aaataatatt gctccatttg tcaatacaga ggacatccat tatttaatca tggaagatca
     9361 ttttcccaat ggacgtccga aattcgaaaa agctggggta ttcttgactg atcgtgcaac
     9421 ggtagataaa gcagatacga tgaaggtgac gacttgcctt aatcctttgc atacgtcttt
     9481 agctattatg ggttgtttac tggggtatag gagcatagct gaggagatga aagatccaga
     9541 tttatcgctg ctagtttctg aaatcgggta caatgaaggc ctcccagttg tggagtctcc
     9601 aggtatcatt gatccaaaga tctttctgga agaagtaatt actgtgcgct tttctaatcc
     9661 aaatattcct gatatgcctc agcgaatcgc cacggatacc tctcaaaagg tggcgattcg
     9721 ttatggtgag acgattaaaa aatatatgga aatagaagtt aaagacccgc agacacttgt
     9781 attcatacca ttgactctcg ctgcttggct tcgatacctt attggcattg atgatcaagg
     9841 aaaaccattc atcccgagtc cagacccact attgacagac tttcagcata agctttccga
     9901 tattcaactg ggtacgcaag atacatcaca tattcatgag aaaatggctc ctattttgtc
     9961 aaataaagaa atttttggtg tagatcttta ccaagcagag cttggcagaa aaatagaaga
    10021 aatgttcatc aagatggtag caggaccgaa tgccgtacga aaaacattac aggattactt
    10081 acaagaacat ggaggaaatt tatcatggaa atgactttta gatggtacgg atcacaggaa
    10141 gaaaagatta ccttagatga aatcagacag attcctgcgg tcaaagggat tgtaggcaca
    10201 ttgatggata taccagtagg agaggtatgg cccagggaga ggatcaaaga actaaaagaa
    10261 gaaattgagt ctcgtgggtt aacactaaaa gtaattgaaa gcgtcaatgt gcatgatgcc
    10321 attaaaattg gattaccttc ccgtgagcag tatatcgaaa actataagca gacaatccga
    10381 aacttggcag aatatggaat agaagtcatc tgctataatt ttatgcctgt atttgactgg
    10441 gtgaaatctg accttgacta ccgcttagaa gacggctcat ccacgttagc ttttatatct
    10501 gatgatattc cagatgatcc aagagaaatc gtcgcgcgca tcgaacattc cagcaatgaa
    10561 tttgaattgc cgggatggga acctgagcgc ttagctcata tcaaatcctt gcttgaagcc
    10621 tatgcatcag tagacgaaga aaaacttcga gaaaattttg cctattttct ccaatcaatc
    10681 atcccaacat gtgaagaggt aggggtcaaa atggctgtac atccagatga tccgccatac
    10741 tcgatttttg gattacctcg aatcgtaaag aatcgagaag atttagattg gttgtgccgc
    10801 atagtagaca gcccttataa cggaatcact ctttgtacag ggagtattgc agaagatcca
    10861 gaaaatgatg tatatgggat tttagcagaa ttttgtcaaa gagatcgaat cccatttgca
    10921 catgttcgaa atattaaatt tttagctaat cgagatttct atgaggcacc gcataaatcc
    10981 gaatacggtt cattagacat gtaccgcata ctaaaaacaa tgtatgacaa cggatttaac
    11041 gaatacatcc gtcctgatca tggaagaatg atctggaatg agacaggaag accaggatac
    11101 ggcttatatg atcgagcatt aggtgctgtt tatctaaatg gattatggga agcaatcgaa
    11161 aaaggaaaca aaagtaaaga taattagtga aaaaaactgt aattttatta tgtaaataag
    11221 aaggatgttc aaattcttga tacataaatc cggaggttgt taataagcat tcggatttat
    11281 gtatcttatt tggtctagga agtaacttga ttttcttttt tcgattgatc catgagtgct
    11341 tcttctttta attcaaagat atattctgag atcctcataa tcactttttt ccagtcttct
    11401 ggtgtgatga ttccttttaa aatatagatt tttttgatat gagaaggcaa ttgtttcaaa
    11461 gggcagtcgc tgataacgat gttgcagttc tccataaaat cattttgtat tttgatcgat
    11521 tcatttgaaa aaatttgttc tatcttaacg atcagatctt tactgatata aaaatcacgc
    11581 gtatagttca caccaatcac aattcgcggc tgttttttgt agcgatcata caaatgtact
    11641 aggtcttcaa ccatccattg cacattttcc ttttctaaaa taactggtaa caagtgttga
    11701 ttttgttctc tgaaatccat ataaaattgt tcaatggcgg tttggacttc tttcaacacg
    11761 ctatgttctt gataaagcat gaaagtagga aggggcgtat ttggttgatt gaagttaaga
    11821 aatccattat aaagtttatt tcgtgcgaat gccaatgagt aaagaatctt ttctttttca
    11881 ggtataaaca aatcaaatac agtacaaaag gactccacca tttctcttga ataaagaaca
    11941 tgaggaacgt ttgctttttt taaaagtttg tattgctcca agcttgtttc ttccgattcg
    12001 attttcgtga tagaaagtcg agctaaaata ttcactaaga tgcgttgttc gcgacaaatt
    12061 ggcagattag gtcgcaaaat atctacagag ggatcaataa aaaagtcaat atattcatac
    12121 tctgtgaatt ctttttgtac gtctttcaca gaagttgcag gaaaattctc tttacatatt
    12181 tttaatagaa aatataattt atctatcata ccgctattta gtcggtcaag tacttctttt
    12241 ttaaaaaaag tattcatcat aaaagccact acttgcggat cttcatcata aaattctgta
    12301 gcagtacttg aaaagatgtt ccaataaata tctaatgctg catattgaat ttgtacctct
    12361 tttccagaaa aagactttct gccattatta gaaaaggaga tagacaaacc gtacaatgct
    12421 aaaaatgcat taatcttttt cattttcgta tacaaataag aggcactata gtttgtttgc
    12481 tgacttaaac tgataatcga atttgtctga cagctgaaca aagaagtcaa gatctgataa
    12541 ctgactgatt cgttgcagta tcttccaaat agacgataat agcagtaagc cggatcaatt
    12601 ccttcaaaat tcaactttaa aaaaggtttt tgcttatcaa tatgcagttc tgttagattg
    12661 agacgctcaa agtcttgttc taattctttg atgtatagta aaaaatttga ttcagacata
    12721 tggaaatgat ctgctaaata ttgtgtagta ataaagaaac gatgttcaga taggaaaaga
    12781 aaaatatcta attttgtatt gctttttttc ttcaagagaa acgttttaat cgcttcttga
    12841 gtttgcatga aagaggctcc tttttactta aattgttaaa acttgaaaat attactgttt
    12901 ttttcataaa tttagacaaa aaaacagtaa acatataggt agaatctcta ctatcttatt
    12961 tcttgcatac aaaaaaatca aggagtgaga gagttatgag atattcaacc atcttaatat
    13021 caacatttgc agccttaagc ttatcgctta ctataaatca gacagtccac acagaggaga
    13081 tagaaacagc caaatggaca gaaaccaagt gggccaacgt caatcgaatt acctttcagg
    13141 atgaattttc atccttcaat tcaggagtcg caaaattaag aaaaggacaa acagcgacca
    13201 tcaaagcaaa aattgactat tcaggagact tagcacctat actacaatca gctgttacat
    13261 ttgagaatgt tgatcccgct ttgtcgattg gctatgacga gaacactttg actatccaac
    13321 acaagcaagc gatatttacc ttcaccgtta cattaaatca ggacttgtta aaaccagcgc
    13381 tttttactgt caaggtatca gatggactac cgaacgatca tcatcattta acgccgtata
    13441 gtcagcggca gacaattgag caagattcag ctatcgactc aggaggagat cttgttgaag
    13501 aaccaacaga taaaccagaa aatgaaaata agccagaagt accgcctaca gaaaatccag
    13561 acggagaaca gaaaccggaa atagaacctg gagaagaacc cgatacagaa actcaaccag
    13621 agccagacaa tgaatcaaaa cctgaaataa cccctggaga aaaaccagat gtagacccag
    13681 aagaaaaacc agatgtgact ccagaaccag atacggattc tggaaaccaa acagtaccgg
    13741 aaacaaatcc agacacagat aatgaaactg aaaatccaga aaaaccagag gtagccccag
    13801 aagaaaaacc agatgtaact ccagaaccag atacggattc tggaaaccaa acagtaccgg
    13861 aaacaaatcc agacacagat aatgaaactg aaaatccaga aaaaccagag gtagatccag
    13921 aagaaaaacc agatgtgact ccagaaccag atacggacgc aagagaccaa ggaataccag
    13981 aaaaaataaa caaaaaaaca attcaagagg atggaaaaaa agagagtaaa aaatcaaatc
    14041 tagcaattct aaaaataaat gaagagcagc tgaataaaaa atcacgaata tttgatagcg
    14101 cccaatcagc tgaaacctta aaaagtagca aggatacaac ctttgctgtc ctgaaacgaa
    14161 aaataaacag ctaccaaaat ccggagagtc acaaaacaaa gttatactgt ggagcggaat
    14221 cattctatta agtatagcaa caatgctttc tgcaaaaaga tttaaacaaa acagatctct
    14281 ctaacatttg aataatgtct gtgaacgcat ttttcaaata aaaagaaata tccagaaaat
    14341 gaccccaaaa taccagattg aaatctgata tttggggtcg ttcatacttt atctttcttc
    14401 atatttattt taagggatat ctgtttcttt tggaagatgg ttcgggatct ttttcacttt
    14461 caatacatct aaaaagaagg taaagatcgg aatgccgaca atcaagcccc aaacgccaaa
    14521 gaaccgttcg ctaacaagta agaccacaaa tgtataaaaa atcggcagtt ctgttttgct
    14581 ggacatcaac ttcggattca gcacataaga ctcaattaga tggacaatca aaatcgtaat
    14641 caggatataa acaacatctc ggatgcctcc ttgggaataa gctatgaaag atagaggaat
    14701 acaagaaatg ataacacctg ctactgggat cagacttaaa atgaaaatca tgatcgctaa
    14761 actcagcagc tgatgaaagc caaatacagc caaggcgatt gtagtgagca acgtatttaa
    14821 aagagcgaca acaaattgag cttctaatac caaaccaaat gtattgacaa acttatcggc
    14881 aaaatagtaa atatcttgaa agaaccaaga aaattcactt tttaaaaaca atcttgagaa
    14941 tacaattgtt tttttctttt caatcataaa aaagaaactt aagatgaatg acatagcaaa
    15001 cgccactgcc atttttccta tatcctgtaa atagccaagc gcaatcgaag cgccattttg
    15061 aagctgttca aaaaaatcgt ttcgctcaat ataagtatgg atatattgta aaacaggatc
    15121 tgcatctttt ggctgatgct cgtaaaaatt aataacggac tggatcatgt caaatgtttg
    15181 atgaataagc atcgggatat actttgtgaa tgccagatag ataaggtaaa cgatcagtgt
    15241 ataaatcatg atagctaaaa cacctgtagg gattcggaca aatcgctgaa tgatttgaac
    15301 aagatgaatc atcaaataag taaagataaa tgtgagcaaa atggttgtaa tcatacttct
    15361 aactaagaaa agaacaaaaa cgacaaataa taaaacagtg agacggcgta ttttttcatt
    15421 cgccaaaaaa cgctgataaa cggtcaaatc gacaacctcc aaataacaaa aaataaacac
    15481 gttattcatt atatgatgga atatgaaaat aagaaagagc aaaaagaaaa accgctaaat
    15541 gacgttatct tatgagttgg ttttcctcat aaaatcgttc atctagcagt ttcagccctt
    15601 tttctggtct tgatgaaaat tatctagcat ttttcgggtc agatgttgca gtgtatccaa
    15661 ttcttcctgt tcaagtggaa gataagactt gatcttttgt ggaatacctt ctgcttgttt
    15721 ttgcaacgca gcaccttgag cagtcagcgt aacatttacg attctttcat cacccgtttc
    15781 acgctgacga ttaatataat ttttttctgc taactttttt agtaagggag tcagcgtacc
    15841 agaatccaga cacaaatcat ttcctagctc tttcactgaa gtctttttct tttcccataa
    15901 aactaacatc acaagatact gggtataggt aagattcagc ggcttgagga ggggagtgta
    15961 gtgtctaatg atttctttag aggcggcata taaaggaaaa catacttgat taactaaata
    16021 tagatcttcc atttttccac ctccgctgtt ttactatagt gtatcatagc ggatttacac
    16081 aaaaaagtct attcactaac tgctttcaga gtaacttcta tatttccagc tgtagctttt
    16141 gaatacggac acactttatg cgctgcctct aataattctt gcgtttcttc cagagaaaga
    16201 ccttcgatag atccttcaat ctctacacct aagacaaagc tcgtttcact ttctgaataa
    16261 agggaaactt gtgcactgac agtagaagcc ccagagatat ttttttgctg tttgatcaat
    16321 tctaatgcac tgttaaaaca tgcactgaaa ccagctgcaa acaattgttc agggttggtt
    16381 gcattttcga cgcgtttacc aggagctgca atattcaatt cgaatgtacg atcgggatta
    16441 tgcacttctc cagagcgtcc gcctgtgttg atcattttcg tagaatacat ttttttcata
    16501 aaattaccac ctttaattat attttataca attgaatttt acacaatata attgtggaaa
    16561 gcaaagaaat ggattggcat aagataaata agagaaagca catgaaacag acgcgctttc
    16621 tcgaatagca aacatataca aaaaatatca gagacaaaaa ataatctcat cataaacatt
    16681 acatatattt ctcaaaaagt tgttttcttt cttcaaaaat tacttcacga tggacctgat
    16741 gaagcatcca taaataacca aaaggatctc tgaacattga gttagtcaca ccaaagtcca
    16801 tcatttctgt catttcttga atctctacac agccatttcg taatgcttta ttatgtgtgt
    16861 cctcgatatc agagacgatg atattgaacc agatcgtatt tggatgttca gcagtaggag
    16921 cagtcaaacc aagagacgtg ttttcatcca gcatatggaa tctcgtacca tacaaggtaa
    16981 aaatgacttc attattgcct ctagggtaat ctgttgcctc aatcagttgt atttcatcaa
    17041 agattgtttg atacagttct agtgctttca aactatcatt taatacaaaa tcgatttccg
    17101 ttcctttatg cataaagatc tcctctcctt ttcagtcgaa cagttactag attcttttat
    17161 tataccagct aaagaaaacg cattcaaaaa aatagcggat ttacttacca actcattcga
    17221 ttggatgata agtaaatccg cgtcccatta cttctgctac gctgctgaca atgacaaagg
    17281 cacttggatc gatttcttct atcaatggtt tcattcggga aaattcatga tcagtcacaa
    17341 cgatcaataa aacctctttt gactttcgat tatacccgcc ttttgcctct agcagggtaa
    17401 ggccacgtcc aatctcagca cttaagcgaa ggcggatgtc ttccaaataa tgttcactca
    17461 tgaccataac agatttcttt cgattgatac ctgtttcgat ataagtcatg acaattgaag
    17521 tgattgcaat agataaaata gcataaagaa actcttctat tccaaaaata aacagattaa
    17581 gagaaacaac gaatgcgtct gtaaaaaata agccaatcga agtattcaag tggaaatatt
    17641 ttttaaaaat gaggggaggg atcgtcgtac cgccgctaga agagttgttt ttatataaaa
    17701 tcgcaactcc taaagcaaaa atcgcacttc caaaaatgac agacaacaac cgatctgaag
    17761 taatcattgt ttctggaact attgcaatga ttaaaggaaa aaccaagctt ccgaaaagta
    17821 ctttaaaaaa gggtttttta cctaaaaata gaagagctag taccaacata acgatattca
    17881 acactaaaat aactatagct cggtcaaagc ctaaagcagc ttccagtaat attcctagac
    17941 cgctgacacc tccagcagca atatgatgag gccctaaaaa catattgata gcgactccta
    18001 atatgaagag ggcaaaaata atcttaatgt atgtccatat aaattgtctc gtttctttca
    18061 tttattcact tccttaattc attaataata ctcttatctt attataactt acttttcacc
    18121 ttaagttaac tttaattaat aaaaaaatta ggctagtcta aattattatg tttcattctt
    18181 ctagaatata cttctacgcc aaaaactgtt aaaaaacttt tactttagaa aattggagaa
    18241 attgatcgct taagataaat tcaggacact aaatagtaca ggaagtagac taaaactttt
    18301 aaaagtttta agtctatcta tttggcaagt ttaaaaaata aaaattcggt atcaaaaaac
    18361 tgttaccgat aacatttttg aaagcgttgt cttttgcttc tctatcactt atagtgatga
    18421 cgtcatatta aaacacaagg aggaaatcaa tggatacagc tgcaatttat catcgaccgg
    18481 aaagtgaata tgcatttcta tatacgaata caagatttcg tattcggctt cgtactagga
    18541 aaaatgatat caaaaaagta tatgtgctat gtggagatcc atataccata acaactgaaa
    18601 aatggtatca aaaacaacga ccaatgaaaa aatgtctaag taccaatgtt catgattatt
    18661 gggaaattga agtgacgagc gaaacaagtc gcttacagta tgcgttccat gttgttgggg
    18721 aagataacac ggactgtttt tacggtgatc aaggaatttt tccttatcga gaaaatgtga
    18781 ttactgaacc aaatttttat tttcgaatac cttattttca tcaaatcgat cgattcacta
    18841 ttccagaatg ggtaaaagaa acagtatggt atcaaatttt tcccgaaaga tttgcaaacg
    18901 gggacaaagc aaatgacccc gaacacactt taccttgggg aagtaaagat ccagaccgag
    18961 aagacttttt cgggggagat ttgcaaggtg tgatggatca tttggattac ttgacggacc
    19021 ttggcatcaa tggcatctat ttttgtccca tatttaaagc cacatccaat cataaatacg
    19081 atacgattga ttattatgag gtggatcccg cttttggcga taaaaaactt ttaaaaaact
    19141 tgattgatga agcacataaa agagggatac gtatcatgtt cgatgctgta ttcaatcata
    19201 tgggtgtcca ttcaccacag tggcaagacg ttctcaaaaa cggagaaaaa tcgatctata
    19261 aagactggtt ccacatccgt tttttcccag tagattctta tcagatgact gacttaccag
    19321 aaactgctga aaatatccca tatgatactt ttgcttttac tccattcatg ccgaaactaa
    19381 atacagcaaa tccagaagtg caaaaatatt tgctggatat cgcaacttat tggataaaag
    19441 aattcgatat tgatggatgg cgtcttgatg ttgctaatga agtcgatcat catttttgga
    19501 aaaaattcag agaagcagtt acagaaatca aaccagacat ctatatcctt ggagagattt
    19561 ggcattcctc tcaagcttgg ctgcaagggg atgaattcca tgcagtgatg aattatgcat
    19621 ttacagattc gattaaagat tattttgcaa aaaagaaaat cacagcttca caaatggtca
    19681 gtggaatgaa tcatcagcaa atgctttaca gagatcaggt gaacgaagga acattcaact
    19741 tattagattc tcatgatact gccaggatct tgaccctttg ccaaggtaac aaagaattga
    19801 tgaagtctgt gatggccttt atgtttcttc aaaaagggtc tccttgtatc tattacggga
    19861 cagaaatagg gatgactggt gaagatgacc cggattgccg caaatgtatg atatgggaga
    19921 aggaggaaca agatctagag ctattcggtt ttataaaaga acttgtttct ctaaggaaac
    19981 agttgtctaa gattatttct gaaggttcta ctcagtggct aatagtaaat gatcgtgaag
    20041 ataagctcta tttcacacgg aaactagagg gacagatcat ctatgtttac tttaatcagt
    20101 caaaagaacc ttgggtagta gaacaggaaa atgaggtgat tcttagtcaa aattgtcagt
    20161 tgttagaaga cgggaaagca gagatacgac aatacggatt tttgatcatg tgttgaaaac
    20221 tgttaccggt aacaacaaga aagcgtttgc aaatgaagat ttgtgcccat tataataagg
    20281 gtgtaacagc acgttgaata caaaggagga aatgaagatg aaaaaaagaa gtgtgaaaca
    20341 gttgggttta gggttaatct ctttaggaat cttaggcgga ttagcggctt gtggcaatgg
    20401 taactcttca gcagaagggg aagccgatga aggaaaaacg ttaacagttt ccgttgattc
    20461 tggatataaa gattatataa acgaaataaa aaacactttc gaaaaagaaa acgatgtgaa
    20521 aatcaagcta gtagaaaagg acatgttcga tcagttggaa tcattagcgt tagatgggcc
    20581 tgctggaaag ggacctgacg ttatgatggc agcatatgac cggatcggtg cgttaggaca
    20641 gcaaggacat ctggcggaag taaaactggg aaatgaagca gcttacgatg aaacagacaa
    20701 agcccaagtg acttatgatg gaaaaatcta cggagaacct gcagtaatcg agacccttgt
    20761 tttgtactat aacaaagatt tagtcgatac agcaccatca acgtttaaag atttggagaa
    20821 tctatccaaa gacagtcgtt ttgcttttga gtcagaagca ggaaaaaata caggattttt
    20881 agctaaatgg actgactttt attattccta tggtttaatt gcaggttacg gtggctatgt
    20941 atttggtgat gatggcacaa atccttcaga tatcggtttg aataatgcag gtgctgtaga
    21001 aggaatctct tatgcaacag attggttcaa aaatgtttgg ccaaagggaa tgcaagacat
    21061 aaaaagtgca ggagacttcg ccagccagca attcatgtcc aataaaactg cagcaatcat
    21121 tgacggtcca tggcaagcgc aaacatacaa agaaaacaat atcaattatg gtgtagccaa
    21181 aattcctact ctaaataatg gacagcctta tcaaccgttt ggcggaggaa aaggatgggt
    21241 agtcagcaat tatgctaaaa acaaagacct ctctcaaaaa tggcttgatt atgtaacgaa
    21301 tcaggaaaat caagaaaaat tctttgaaat ggtaaatgaa atccctgcaa accaacaagc
    21361 tagggaaaca gcaaaggcta aaaacgatga attaacaaca gctgtgattg aacaatatga
    21421 aacagctcaa gcgatgccaa acatcccaga aatgggcgaa gtttggacag gtgcagaaaa
    21481 cttgatgttc gatgcagcat caggttcaaa aacaccaaaa gaatccgcag atgaagcagt
    21541 aaaaacaatc agtgaagcca tagaacaaaa atactgatta aaatgataac cgtccatttt
    21601 tataaaaaat ggaacaggtg cttcagataa aagtggcaag agcgagatgg aaaattatct
    21661 tgctcttgtt gccattatct taaaagcagt ttgcggttta gcaagtttag agggggcatt
    21721 cagatgcagc aagataaaac aagcaatatc aacgaaaaaa aaatcacgct ttgttcactt
    21781 attccaggga tggggcagtt tgtaaatggc caagctttta aaggtatcgt ttttttcgcc
    21841 atattcgtcc tattcattgg tcagatgctt ctgggcggat ttcatgcatt ggtaggattg
    21901 gttactttgg gaagtatacc aatggaagat cattcattat ttattttgat tgaaggcact
    21961 ttgcaattca tcattacaat cattttcttg attttttacg gtttgaatct tttagacgct
    22021 tatcgagtag cgaagatgcg tcaagagggc aaaaaaatca atcggacgat gaaggaagtc
    22081 atacataata taggtgatga aggttttcct tatctattga cacttcccgc ttatcttctc
    22141 atgattttta cgatcatttt cccagtccta gttacattgt tcactgcatt tactaattat
    22201 gacttcaatc atattccacc agccagttta attgattggg taggggctaa aaactttttt
    22261 agtatcttct ttttaagctc atatcgtaat actttttttg cagtcttttc gtggaccgtg
    22321 atttggactt tatgtgcaac aactttgcaa atcacccttg gtattctcac agcggttgtt
    22381 gctcaccaga aatttattaa attcaaacgt attttcggta tcattttctt attaccatgg
    22441 gcggtcccag cttttattac tatcatgagt ttttcgaata tattcaacga tagcgtaggt
    22501 gccatcaata ctcaagtgat tcctttcata aaccagcttc cttttgtaga tatcagtgca
    22561 atctcttgga aaacggaccc gaactggacg aaagtagcaa ttatcttagt gcagggctgg
    22621 ttaggatttc cctatatcta tgtgatggtt acaggaatct tacaatcgat ttcagaagac
    22681 ttatatgaag cagcaaaaat cgacggagca aatgcatggc agcgcttttc aaacatcacg
    22741 cttcctgctg tcttcctagt ggcagcgcca acatttatta cacagtatac ggggaatttc
    22801 aataatttct ccatgatcta tctgtttaac aatggcggtc ccggaagcgt aggcggagga
    22861 gctggttcta ctgatattct tatttcctgg atctataaac ttacgactgg aacttctccg
    22921 cagtattcta tggcttcagc aatcacgttg attatctccg tcatcgttat ctgtgtgtca
    22981 ttgctggtat ttaaaaagac aaatgcgttc aatatggggg attaacaatg aaaaaatttc
    23041 attcgagtgc tcgattccaa aaacgacttt ctcacttttt tacttacttt tttcttttaa
    23101 tactgtcagt cattatcatc tatccgcttt tgatcacagc aagtactgcc ttcaagtcag
    23161 gaaatattgc agcttttagt ttagatcttt caagtgactg gactttagga aactttactc
    23221 ggctattcag tgaaacactt tacgggactt ggtataaaaa tacattgatc atttctgtcc
    23281 taacaatgat cgtacaagtg actgtagtaa ctttggcggg ctatacttat agtcgctatc
    23341 gttttatcgg ccgcaaatca agtttgatgt tctttttagt gattcagatg gtaccgacta
    23401 tggcagcatt gactgccttt tatgtcatgg ctttcttatt agaagcgctc gataagtact
    23461 ggttcttgac aatgatctat ataggcggtg gaattccaat gaatacttgg ctgatgaaag
    23521 gatactttga cactgtacca atagatttag atgaatctgc taaacttgat ggggcagggc
    23581 atttcaggat ttttttccag attgtattac cgcttgtcaa accgatgctc gccgttcaag
    23641 cattatgggc ttttatggga ccttttgggg atttcatgtt agctaagttc ctgcttcgaa
    23701 cacctgaaaa tcagactgtt gctgtcggct tacaaacatt tatttctgat gtgacaaacc
    23761 aaagagtctc tctttttgct gctggggcaa ttttgattgc actaccgatt tgtctattat
    23821 tcttcttttt acaaaagaac tttgttaccg gcctgacatc tggcggaaca aaaggatagg
    23881 agcagagtat catgcaaaca tttccgttaa actatttttc cgcattacgt acgccaactc
    23941 aagtgtttgc gggacgcaaa ctattatcat ggcctaaatt tttcttgata tttgtatttt
    24001 tagtttcctt gatggtcatg cctgtgactc ttttttatgc caatcagatc caagcgattc
    24061 cattagaaca atttctatcc gttcattcgc tgatcgatga acaaggaacc caaaaatttt
    24121 ctgaacttga attatctgaa actgggttac aagcatcgca acaaacgata gctgtgaccc
    24181 ctgaaatttt ggtaggtgtg tctttatctg agaaacaaca atccgatcat ggaactttta
    24241 ttgattttga gaaggaacaa tgggtgatcc aacaaaagga taaatctggt atacgccgct
    24301 atacgatgaa ttatagccca tctttccaac cagattctgt acgtacgccc gaagatttcc
    24361 aacgattttt agaaagagaa ttttatgcca gtaatcgtcc aacaatcatt ttatcttata
    24421 gtttaagtct tggtcttgtc ctatttgtca tgacgagtct cattttattc ggggcttcct
    24481 ttttcttgtg gatgacaaga aaaagccaac tttcatccat tcatacattc aaagagagtg
    24541 caaatttgat gctgaatgtt atgggaatag gttccatggc agcagcagtt gtagggttta
    24601 tccactttga ctttatcttg atgctaagtg tccaaacaac gataactgtc ttgctgcttt
    24661 tatgggtttt tgtcaaaaca agattcaaag ataagcgtgt cgaatgacaa gtttaagcga
    24721 tttatgcgac aatgaatgtg aaaaaaatga aaaataaagt agtttttgaa aaatttctga
    24781 aaaaattaaa cttcttagtt gattcttttc ttttttagta ttaacgtaat agggtagttt
    24841 ttttaaggag gaaaatcatg ttagagaaaa ctttatacaa tcaattattt tcacgttctt
    24901 tctcgctccc tgtcgaagta aattattggg acggtacaac gaaacaatac ggagatacgg
    24961 acactcctcc ccaaatcaaa atcaatatcc atgaagaaat cccaatgaaa gagattacaa
    25021 gtaacgcttc tttggcacta ggagaagcct atatggatca tcgaatcgag atcgagggaa
    25081 gtatccaagc attgatcaac gatgcttatc agcaagcaaa cagcttttta cgaggaaaag
    25141 attatctaaa atggctgcca aagaaagaaa aacatacgaa acaaaaaaac aaagaagata
    25201 tccatgcgca ttatgactta ggtaacgact tttataaact ttggctagat ccaactttga
    25261 cttattcttg tgcttatttc aatacacctg aagatacgtt ggaacaagca caaatcaata
    25321 aagtccatca tatcttagac aaactcttta tcaaagaagg cgaaacgttg cttgatatcg
    25381 gttgtggctg gggaacattg atgttcactg ctaccaaaga gtataatgtc aaggcaactg
    25441 ggatcacact aagtgaagaa caatacgatt tgattaccaa aagaataaaa gaagaacatt
    25501 tagaagataa atgccgtgta ttattaatgg attaccgcga actaaaaggc gaaacgtttg
    25561 atcatatcac aagtgtaggt atgttcgaac atgtaggttc tgaaaatctt gaaggttatt
    25621 tcaaagtggt aaaagattta ttgaaaccaa aaggaacagc tttgatccat ggaatcagcc
    25681 gacaacaagg cggtgcgaca aatgcttgga tcaataaata tattttccct ggcggttatg
    25741 tccctggtgt tactgaatta gttgataata ttacaaaaaa cgatttgcaa ctgattgatt
    25801 tggaaagctt acgtcgtgac taccaattga cattagaaca ttggacaaag aattttcatc
    25861 aagtccaaga tcaagtcacg aaagaaatgg gtgattcctt ctatcgaatg tgggatctat
    25921 atttacaagc ttgtgcagct tcatttgaat caagtaatat cgatgtgatt caatatttgc
    25981 ttgttcaacc tggaaacaat gacatcccaa tgcatcgtgc ataattgagg caaaagtact
    26041 gtttaaagac tatttaaaaa gaagctaagt tttatgatgc tccagaagtg aacttttttg
    26101 tctaacttct aggattgtct ctaaagctta gtttcttttt ctttatattt tcataataaa
    26161 agtttggttc tttaattttt aaacatgaca gaaaattttt tcttcgttat acttgtaata
    26221 gaatactatt ttataacaaa ggggatcgaa tcaatgaaaa aaactgttat ttatactagt
    26281 ttatttgcag ctttgttttt agctgcttgt caatcaaata ccaatcaagg cacatctggg
    26341 aatacgtctt ccagtagcga acagcgctct tcacaggtat cggactcctc aacaaaagca
    26401 agcacatctt cgtctagcca gacaaaaagt tctagtgaag caagtactca gtcagatatc
    26461 aaagtgtctg cagctcgtgc gatcgaattg ttccaagata aatacccaga tactgcaatt
    26521 actagtttgg aattagatag tgattgggga tcttacttct acaagataga aggtgtcgat
    26581 gatcaaaaag aatacgaagc aagaattgat gctcaaaatg aaaaaatgga gacagagaat
    26641 ccagaaactc tagatcgaga tgaacaaaat ggtcaaaaga aaaaagaaga tggtctggat
    26701 gttgataaat tgatcacgat tgaggaagca gcaaaaatcg ccgtcgacaa agtaggaagc
    26761 ggtacggcaa cagattggga tttggataaa gatttaggta ctacttattg ggaagtcaaa
    26821 gtaaaagacg gcaatcaaag tacatcagtc aagatcaata gccaaacagg cgaagtactg
    26881 tcaactgaac aagatgatta agaatttctt cggaaaacaa gagttgattt ttcttttagt
    26941 catgatacac tagacaaaat aacttgtttg aaggagcgat ttacttgagt ttagaaacga
    27001 cctttgccaa tcatatcttt gccaatcctt tgatgaatgc atctggtgtc cactgcatga
    27061 ctacccagga attagatgaa ctggctcatt cagaagcagg agcatttatc actaagagct
    27121 gtacgatcaa tgaacgaaaa ggaaatcccg aaccacgcta ttttgatgtt cctttaggga
    27181 gtatcaattc tatgggactt ccaaacttag gtttttctta ttatctagag tatgctcttg
    27241 cgtatgaaaa agtgcaggaa aaccaaaatc aaccgttatt tttttccatt gccgggatga
    27301 gtgtccagga aaacttggaa atgcttgaga aaatagaaaa aagtgggttt aatgggatca
    27361 ctgaattaaa tttatcttgt cccaatgtgc ctggaaaacc acaactagct tacgattttg
    27421 aggccactta tgaaacactg aaagaagtat tcagcatctt ttctaagccg ctaggaatca
    27481 aattgcctcc ttattttgat tttgctcatt ttgatcagat ggctgatatc ttgaatcagt
    27541 ttccattgac ctatgtcaat gctatcaaca gtgtgggcaa tggtttgtat atcgatacag
    27601 aacaagaagc agtagtcatc aaaccaaaag aagggttcgg cggcattggc ggagagtata
    27661 tcaagccgac tgctttggcg aatgttcgcg ctttttatac acgtttgaaa ccagaaatcc
    27721 aaatcattgg tacaggtggg attcggacag gacaagatgc atttgaacat ctgctatgtg
    27781 gcgcaagcat gttacagatt ggtaccgagc ttcataaaga agggacggaa attttttcta
    27841 gaatcataaa agaattaacg cagattatgt cagaaaaagg atatacgtca attgacgaat
    27901 ttaaaggcaa attacgcacc atttcatagc aaagagacga aggtcatgat tgatcttcgt
    27961 ctttttttat aaaaaacact cgtctgttca ttcctgtgca agcgtactca ttgtatgtta
    28021 gacgaacttg tgggaaaata acagaggcaa aaaggaggat aatatgaatg atgcaacaga
    28081 attagcaaaa gagcttaaag aaaaagaatt tagttttcaa gaactagtta cggatataca
    28141 gaaaaaaata aagaagcaaa atcatgaatt gaatgcgttt gtcgcgcttg aaccattcga
    28201 gagtaattcc cacgagctat tgattcccca gtcagaaaaa gggccattgg ctggtatccc
    28261 atttccttta aaaatgctcg gtcaagaaaa aaagggatgg ctagctactt caggatctcg
    28321 tttatttgaa acacaccgag cttctcatac atctaattat gtgcggcaag cagaagcgat
    28381 aggtctagtt ccttttggac aaaccaatgc gccagagttt ggtttcaaaa atattacaga
    28441 cccagtcatc tatggcccag caagaaaccc ttggaacctt gaatgtacac cgggcggatc
    28501 aagtggagga gctgctgctg cagtttcatc aggaatcgtt cctttagctg gtgctagtga
    28561 tggcggtggt tctattagaa tacccgcttc gttttgcgga ttgattgggc tgaaaccttc
    28621 gcgagggacg atgccagttg gtccatatgc ttggagagga tggcaaggag ctgctattga
    28681 tttcggcttg acagtttcta tgagagacac ggaggcttta ttttatggga tgagaagtat
    28741 ccattccggt gcgccatatc aagtatcgcc agttgagtgg caaacacatc caagaaaaaa
    28801 acggttgaag atagcttttt gtgttgattc accgatccac tcacagatta gtgaagaggc
    28861 agtacttgct gtaaaaaaag ctgtagattt ccttggaaaa gaagggcatg atttgacaga
    28921 gattccttac ccactagatg gtcgtaaact gatcacgtct tattatcaga tgaatggcgc
    28981 agaaacagca gcaatgatcc gctcgattga aacaggcatc cagcgagctg tcagaaaaga
    29041 agaacttgaa cccatttctt ggactttgtt ccaatatggt cagaagctct ctgccgctac
    29101 ttacatcgat tctctgcatg tatgggatga agcagcaatt gtcatggaaa acctacatca
    29161 agaatacgat ctattccttt caccaacgac tgcatttacc gcccctaaaa tcagcgaaga
    29221 tttgcaaagt gatgcgataa gagcacagat ggaacacatc agtgattgtt ctgaagtaga
    29281 aggtttagac gttgtttctt ccatgtttga ggagagcttg aagatcacac cttatacaca
    29341 gttggctaat ctgactggac aaccagcaat cagcttgcct actcatttga caaaagaaaa
    29401 catgcctcta ggaatccaat ttatggctgc cagaggaaga gaagatttgc tatttcaaat
    29461 cggctatcta tttgaagcaa atcatcagtt ccatttacca aatccatgga aatagcagaa
    29521 acaaggagaa gaagaatgaa gaaaaaaaga ttgtttgctc taataactag tgcctttttt
    29581 attttaagcg cttgcggtac agctgccgct aatcaggaag ataacagctg gagtaatgta
    29641 gaaaaaaaga aagaattagt agtagcgact tctggcacac tgtttcccgc atcttattat
    29701 aatgatcaaa atgaattagt tggttatgat gtagatttgg caaaagaggt ggctaaacgg
    29761 ttaaatgtca aaatctcctt taaagaatac aacgtggatg gacaaatcac ttctgtttca
    29821 aaaagagaat cagattttgc tgcgaacgat tttggtatca caaaagaaag agaaaaaaaa
    29881 ttctcccttt cagagacttt caaatattca tttgacagta tgatcgtacg aaaaaaagat
    29941 gattcaggaa tccactcact tgaagatctt aaagggaaaa aagcagctgg cgaacccaat
    30001 actagctata tgcgtttagc ggaaaaacac ggagctaaat tagtcacata tgacaatgcc
    30061 acgaatgatc agtatttaag cgatgtagca aatggtcgaa cagatgttat tctaaatgat
    30121 tattatctgc agaaaatggc cgtatctgct ttaccagata tccctgtaaa aatactggag
    30181 aacgtttatt tcaatgaaaa cgaaagtggt tttttattga aagaaggaaa tgatgctctg
    30241 aaaaagaaaa tcgatggcgt attaaaagag atgaaagaag atgggacgac aaagaaaata
    30301 tctgaaaaat attttcaaac tgatgtttca gtcaaaccga aagaaacgat ggctgagtcg
    30361 gtgagtgagt gatgtacttt cctctaattg atttttccct catgtggact tcacttcctt
    30421 tcgtactgca aggcttggta tacacattag ggattggctt cgtgtcgttt cttttaggaa
    30481 atctggtagg gttgcttttg acagttttag gtcttttgga ttggctgcct ctgaatgtat
    30541 ttattcgttt ttatttatcg ttctttagag gcattcccgc actagtcctg ctgtttctgt
    30601 tatattttgg gttaccttat caattaagtg ccttaacggc ttcagtcatc tgctttacga
    30661 ttaccagcag tgcatttatt ggtgaaatct atcgaggatc actagcaggc gtttcttcag
    30721 gtcagtggga cgctggttta gcttctggtt tttctttctt tggggtattg aaatatatcg
    30781 ttttgccgca agcttttcga atctcagtac cggcactcag taacgtagct atggatctag
    30841 tgaaaggtac ttcgttagca gcaacaatca cagtgccaga aatatttcaa aaagcaaaga
    30901 tcataggcgg tcggacattc gattattttt ctctctatat tttagttgca ctgatttatt
    30961 gggtcatttg tatcgggatc gaaaaagtgc aacagtattt agaaaaacgt tctatgcatc
    31021 agtcaatctg aaaaatagaa atggtgctag cgtggctggc accatttcta ttttttgttt
    31081 cttgtatatt ctgcctagta ttttaaaacc atttcatgta aaatgtaaat cgaaaatatg
    31141 ttcggaggta gaaaacatga agaccccgct aaccatcgaa atagaatcct cgttatacca
    31201 atattgcatc gagcaaggcg gcttggttgt agaagaagtc acgatgcctg atgaccaagg
    31261 aattgtagat acgcttagct gcttgacaaa atttgatgga agccgagaat ggcgatgcta
    31321 tgagctgaaa gtgacaaaag cagattttcg ctctacagcc aaactgtcat ttgttggaca
    31381 ttataattat tttgttttac caagtaaact atatgaagaa gtaaaaactg aaatccctac
    31441 aggaataggt gttttagtgt atcgtccgta cacggttgaa gaggagatgc ctgcctctgg
    31501 tacatttctg attgcgaaaa aagcagcaaa gaaagagctt gctgtaccgg aagaagcttt
    31561 gacaaaccgc ttcatggctt ctttattcag ggaagtaaga aaagcaaagc aaatggagcg
    31621 aggcgtaaaa tattttccaa cagatcaatt gtacaaagaa ttgaaaagac gttcagaaaa
    31681 tcaagatcca ttttctaacg aacgatatta tgaacggttt ttagaggaaa tagctagtca
    31741 ggcaatcaat gagttgcaag aagaagttat cgcgcttcag catgattatg aatatttgag
    31801 gcaacaacag cagatccgtc ggttgcctac agagccattg gagtgaaaaa tatgtactat
    31861 ccttatttaa gaggaaaaca atttgaccta ttagcattaa aagaagcact gtcgcgagga
    31921 ttgctctcca ataaaatcca accagtgatc gaaccagtac gtgattccgc tacgcttaaa
    31981 aatgtgatcg aattatttca aaaaaagcac catccaatcg ctgtgatcca aaatccccaa
    32041 gtaggacaat tcaaattatt cgatcagcat gtgcacagtt ggacagtcaa agaaaatagc
    32101 tctgtcgtcc ctgcacagat cttaacgcca gaaaatctca gtgaagtact ggattcacct
    32161 ccagcgtttc ttgttttcga tggacagcac tacccaaaag atacagaggt gtggaaacag
    32221 ttggcaggag ttgattcgaa atttttgata ccagatacta gtcgctttcg catctggctg
    32281 cccgaaaaca aaattgtgat ccgtgactct tttcaaacga gaaagcatgt tgaaagttat
    32341 gcagataaaa cagatgactt ttttagtgat gactatcttt ttttccacgc agacggatat
    32401 attggatttt ctgatttcac gatcgaaggt agccgttatt tcgataaagg gttccctagc
    32461 cgagcgcttg ctatccatct aacgtatatt gatgcttacg gcaatatacg cgtgaaacat
    32521 tttgtctctg acagtaacga ctctgctaaa gaccaagcat tgaagtttct tgaagcagga
    32581 gataaaatga aaaaatggat catgcgtcac catcatcaac tcttgattac ttcaggaatg
    32641 attgaattat tggctcttta ccagcaacaa aaattccctg gactgggagt gttgaaaaag
    32701 tggtcactta tgcatcattt ggaacttatt agtcacctgc tagatcatcc aaaagattgg
    32761 cttaaatatt attcaaaagt tcaggaacta tatgaagtga tccaatgatt agataatgta
    32821 aatgaaaaag gaatagaaaa gaggaaactg gatgtatatt cggcaaacaa ggaaagaaga
    32881 agtagaagaa gtggtagaaa tcattaatgc cgcagcggat ttcattgctt cgcaaggctc
    32941 tcctcaatgg caaaacgggc agaaaccaac aaaagaaacg attttgaacg atattgaaag
    33001 aaaagaaagc tatgtattaa tagtggaaga tcaaattgct ggaacagctg cattagtctc
    33061 aagcgtggat cccgtttaca caaaaataga tggtagttgg aaagaatcaa ctggtcctta
    33121 tttatcgatt catcgtgtcg ctttagcaga aagtactcga ggaaaaaaac tagcaaaacc
    33181 gttcttagaa catttgttga cgattgcagc cagcaaaaat atccaagata tccgtatcga
    33241 tacttatcca gctaatgaac cgatggaaaa gaccatctat tctgctggat tcacttatca
    33301 agggatgatt gaatttcctt ttgaacacgg cgaaagaaaa gcatatcaaa taatcatcaa
    33361 ttgactataa aatcatctga gcaaagataa agacattaac actactgaaa aaaacaatca
    33421 tatgatagcc aagaggttgt aacagaagtg gccagcttca aaaaacaaga aagaatttcc
    33481 gaaaatgctt ctcaaatttt tgtggaattt tagcgtattt tacgaaatag ctgctttctg
    33541 aaactccctt catcgagagg tcgtgacata gcttttgtca cgacctctcg gcttatccta
    33601 cgagtattat tcgatacatt tatatcaata atcctttttt tattttatct gcagcttctt
    33661 ggaacgctcc atcgtttgac acgactaaaa gtgaggggat agctttcaaa cgtttcaact
    33721 gtgctaaatc ttctacataa accgccagtc tggctgaaat ctgttcagat gaatctccac
    33781 gttttttcag gcgcgattgc aatgtttctt tagagatcgt aataaagata ggacggacta
    33841 ccgtcccgaa atactcatat aaatgccaaa aaccatttgc tgtcaaaacg gcgtaacaat
    33901 ttcctactgt cagtttcttt ttaatttctg ctttactgga accatattta tgttgagcat
    33961 attggtccca ctctgcaaac tcatttccct tgatcatctg attgaatgta ttgtcagaaa
    34021 caaaataata atcctcttga tctttttccc caggtcttgg tgatcgattc gtgtaagtaa
    34081 tgatcttttg ttccggctga aaaatagctt ctgcgagtga agtttttcca gaaccagaag
    34141 gaccgataaa tacatagcaa taattcattg tcatttctcc tttgatgatt gaacaagtga
    34201 aaaagctttg gaaaatattt ccaaagcttt taaaagtaac tttgcttttt tgtatattat
    34261 accagcaagc cagtcacaat agcacttaaa aagctgacta aagtcgctgt tagcaaaatt
    34321 ttcaatccgt gttttgcgac aagatttcct ttttcttcat ttaatccctt catcgcacca
    34381 gaaatgatcc cgatagaaga gaagttggca aatgaaacga ggaagacaga tataattgct
    34441 gttgtacgct cagtaaaatg gaaattacca tttgctaatt ctgtcatagc aacaaattca
    34501 tttgtaacca gtttagtcgc catgatacta ccggcatcca ctgcttcttt ccatgggatt
    34561 ccgctgatga aggcaagagg ggcaaagatg taacctagga tctcttggaa aggatgccga
    34621 atatcccgtg gaagatagca ttgatcatgg caatcaaagc aacaaaaccg ataagcatag
    34681 cagcaaccgt gatcgccaca tggaaaccat caagaatgta ttctcccaac atttggaaaa
    34741 atgtctgttc tttgttttct tcaatgatca gctcatcttc tttttcttct aatacatagg
    34801 gatttacaat tgaagccaga atataaccgc caaataagtt caaaacaagg gcagtgatca
    34861 catatttaga atcgatcagt gccatataag atccgacgat cgacatagaa actgtagaca
    34921 tagccgatac actcatggtg aacaaacgtt tctcagatag gaagggtaat tcctttttta
    34981 tggaaataaa aacttccgat tgtcctaaaa tagcagaagc tactccatta taagattcca
    35041 atttgcccat cccgttgatt ttacttaatc ctagaccaac agctttcata aataatggaa
    35101 gaatcttgat atagcgtaga ataccgataa tagcagaaat aaatacaatt ggcatcaata
    35161 cggaaagaaa gaaaggtgca cttcctttat ttgctacacc ggcaaaaaca aagtcaacac
    35221 cttgcccagc aaaagcaaga agatgatcaa acatttttgc caatacagaa acaaccgctg
    35281 taccaaaagt tgtacgtaat aatacgaaac caagaacaag ctgtaaaacg aacatcacaa
    35341 ttagtggttt caatttgatt gcttttttgt tactgctgat caaaaaagca agccctaatg
    35401 tgacaaataa accaataata cctaataaat aactcaaata atcactccta ttccaaattc
    35461 cgttttattt tacctgtttt gcaaataaaa tactaatctt tagtgaaatt ttcattactt
    35521 ttttagagtg aaacgcattc attttccatt agaaaataaa gcgaacaaaa taaaaggttt
    35581 aaaaagtgta acgtcttagt aaagtctata aaaaaacgaa actatcgatt aagctaatag
    35641 tttcgttttc aacatttata agtaaacttt ttctattggt aatatagatt ttcggaaggg
    35701 tagacaggtg cgcaggtaat atcgattcct agttttttca atgtttgttc atcattttta
    35761 ttgaccatca cagtagagtg ggcttgtgct ccctcaagtt cagctagttt atcataagca
    35821 acttgagcga ttggattcgt tactgcactg attgataaag cgatcaagac ttcattgatg
    35881 cttagtgcat ccaaagagga atgaagtgtc tttgatttca atccttgtat tgtttcaaga
    35941 actaatggtg acaataaagg aatgtcatct gcgatatggg ctaaatgttt tactgcattt
    36001 aagataactg ccgctgacgc atccatcaat gaacttgtac gcccggtaat gatgacttca
    36061 tctggtaatt cgattgcaat cacagcagaa ggatcttttg taggactttg cgcttgaatc
    36121 ttatctgcat agtcatgggc agggactacc acgtttcggt cttcaggacg taaaccgact
    36181 tcttccataa tcagtttgat tcgattaact gcttcttcgt cgatcaatcc ttttttgaag
    36241 tcgcattctg tttggaaata acgacggatg atttcttgtt tagaggcttc ttggacaacg
    36301 gtatcatcca cgatcccaaa tcctacacga ttcacaccca tgtcagtagg agattgataa
    36361 acagattctt taccagtaat tttttcaata atacgtttga ttacaggaaa tgtctcaaca
    36421 tcccgattat agttcacagc tactttattg taggcatcaa agtggaagga atcgatcata
    36481 ttgacatctt ttagatcgac tgtggctgct tcataagcaa tgttcagcgg atgtttcaac
    36541 ggaacattcc atactgggaa agtttcgaac ttggagtaac cagctgcatg tcctttttgg
    36601 ctttcatgat acagttggtt caaggaagta gcgagctttc cacttcctgg gccaggagct
    36661 gtcactacaa cgattggttt agttgtttca atatactcat tttttccaaa accatcttct
    36721 gagacgattt tttctacgtt gactggatag tcttcgattt ctgagtgttt atagaccttg
    36781 atgtttcgtc tttctagttt attgataaag actttcgtgg caggctgtcc actatagcga
    36841 gtgataacga cactgttgat taataagcca taaccacgta attcatcgat taaccgcaag
    36901 atatccatat cataagtaat cccataatca ccacggatct tattacgttc aatatctcca
    36961 gcatagacgc aaatcagtat ttcagcttga tctttcaatt tttgcagcaa tttgattttc
    37021 gcatcttctt caaatcctgg aagtacacgt ttcgcatgct tgtcgtcaac tagcttccca
    37081 ccaaattcta aatataattt gtcatagtgg ttcactcgtt ccaaaatata cgctgactgc
    37141 tcttcaatat atttttctga atcaaaacca atttttttca ctaggttccc tccttaagta
    37201 ctaaagcatt ttttcatttt tttgaggatt cgtcaactgg aagagcgaaa ttcctcaaaa
    37261 aaacaaagaa aatggtttaa accaacttgt ctagatagtt attcattggt atgatagttt
    37321 ttgataagga aggtgctaca tgaaaaaaag acagaaaaag aaaaacgcat ataaacacta
    37381 tatccgttcg atttttaccg gttatgaaag aatgcttgaa gatcccgaat tggaacaatt
    37441 gacgtttact tatctaaacg aagaaacgca gctaactcgt gatgagcatc agcgcattca
    37501 tttcacaaca agagatctgc ctagtaaata aaaaataaga taaaggtcat cggattcgat
    37561 tctgtcctat cagatggaaa gactagttga tcgaaaaaaa ggctgtacca aattttggtg
    37621 cagcctgttt tatggagcat tgcccgctct tttttataac aattttttac agaaaatggt
    37681 actattgaag tattaataag tgaaaaacag atgagtaaga ggaggcaagt agtatgaaag
    37741 agccagatac aaatgcaaat tatgagccag acgaactaga ggagacgaat gcggatcagg
    37801 atacaggaca agaatcgtct tctttttacg atatcaaaga aaaagcaagc atgaatcttt
    37861 cccaattatt agaagactta caggcttttg aaaaagctgt ccgcgaagaa gatatccctg
    37921 agatctaccg tttatacaat ggccgattga atgaagaatt aaaaagaagc tcaaatgaaa
    37981 atcacgagat cgatcaattg ctgatgcgta agatccatga tcgtttttta caggaatttc
    38041 cttttatgga acaagtagaa aacatctcgc caacgatgag ctattacaaa atcggcactt
    38101 attaccatga tcggcccacg gtcggtattg atgcaagtct gccagaaatt tttgttttgc
    38161 ctaagatcga tgaagagtgg gagaaatatt cccaaccgga gtcaacggac tatgacaaaa
    38221 aaatcaatga gctagacgca aaggtgatca ctgctcagac agaaattgaa cgtttagatg
    38281 aacaaataaa agaaatcaat cgacaaatga ctgatttgaa cgacaataaa ggattcttga
    38341 atcgtaaaaa aatcgaggaa gaaattcaag aattagagaa gaagaagcaa gtactatcta
    38401 atgaaaaatt aggctggctt ccttatattg agacgcctga aacaatccag cagcaaaaag
    38461 aagcattgaa gcaagaagca agagcagacc agcttcgtgc agccatcgta gaaaaagaac
    38521 aaaggcaaat cagacgctat ttcggtagca aagagggatt cggtcaagca atccatgaat
    38581 tcttgatgaa ttatcttggc aatgagaatc ctaataatca atctaatgaa ggaggttccg
    38641 agtatgaatg aacacgatga agcagaatgg acaaaaaatg aagaacaaac agaagatcat
    38701 gaagaaacga acacttcatt ggaagaacaa acaagtaatc ctctggatga cacagaagaa
    38761 atccctatgc tagaggaaac aaaaatacac gaaaaagaaa aagtaactcc gacgaatacg
    38821 aatactgcag aaaacaccca tgcttacgaa ataactgaaa atcccgggta tttagaagga
    38881 aaagagcaag atcatcaaga tatcgtcagt ttgattgaaa cagcggaagc agaattagcg
    38941 gatttacgta tgagaaaaga tttgatcgaa tcagattttc cacaattatt agaatcatat
    39001 gatcgtttta tattgaatga agaaccaatc tccacgatcg gaaagacaag cctgatcgaa
    39061 tacttcacgt atgaattact gaaaccgttg aatgatattg gtctggaacg gtcaaattca
    39121 gcttatgaca catggaaaac aagacatttt tcgatcaatt atacgttgaa tggacaaaac
    39181 gaattagtct tttcctttgt attaccgacc atcgatcaac gataccaagt ggaatcgatg
    39241 agtctcctaa acgtatcacc agagacaatg gaaatcaatg tccaagatga ccgggtgctt
    39301 tctttgatcc gacactggtc agtggatcga gtattctctg cagggcagat cacgatattc
    39361 aatcacaaat tgaatcaatt attagcccat gcaagaacac ttggttttac cgttaatcag
    39421 acattactag acaatacgaa gccacttcgt ttgaatcttc agagcgaatt tgaattgacg
    39481 aatgaagtat tggatgatat ttttatcgtg gcaatgaaaa atccatccta cgatatggaa
    39541 aagatcaacg aaactactta tcaagtacga ttagataaag gacagtcttt aacgataaca
    39601 acaaacgaaa aagatcaaac agtcttgtcg atctcatctg gagactaccc acgatctgtc
    39661 attgatttct ttatcaatta cgaattcttg gtcccattaa tggtgagaaa gtcctgattg
    39721 gataagttgg attaccagat gtcattcaga taattctgtt ccaaaggact tgcggcagtt
    39781 atccagaata attgtcacaa gtcttttctg tatgtactaa atggacgtga ataacttgct
    39841 gatgaaggag ggatttcatt aggaatgtcc acaaataaaa tagcacagct tagcttattg
    39901 tctgctgctt gtgtagcagg taggatcgct tttcaattta ttccgaattt ccagccaatg
    39961 actgctattt ttttatttat agtactttac ttaagcttaa aagatgcgtt aattgtcatg
    40021 agtctttcta ttgcgatcag cagtttttat tttggtgttg gaccatgggt catcggccaa
    40081 tggatcagct atactgttgt tctgagtttg ttttcaatcg tctgcttgag aaaaacagtg
    40141 caaaggaatc tatggttaaa gggagtctgt ttttttctgg cgggcatggt ttacggaata
    40201 ggtatgaccg tttttgatac gctgttatat cgtttgcctc aaccttggat ctattacctt
    40261 caaggggtgt cgtttgattt gatgcacagt ataggcaatg ttgtgttctt tcttgttttt
    40321 ctgccagtcg tcaaacgttt ttacaatcat tcaggaggaa aaaatgaaaa aaataattta
    40381 tagtttgctt gcaatgagtg tcagtatact cattttgaca agttgcagta caacctatac
    40441 acaatcggct tccaaccaaa aggaggaagt aaaaacatcg caaaaagcaa caatcacgtt
    40501 acaagaaaat ggtcaaaact tttcggaaaa agaagtgttc ttcaaaaaag gcgatgattt
    40561 actgagtatt ttgaaacgaa attttgaagt caaagaagat aacggcttca tcacttcgct
    40621 tgaagggcac tcacaggatg agaaaaatca actctattgg atgtttactg tggacgggaa
    40681 aagtgctact actggtgcca aagagatcaa attgaatgat ggacaatcgg tcattttcaa
    40741 tttgtctaaa ctataagttt cataaaaaac tgttaaaggg cgaatattgc cataattcag
    40801 tgagttcagt tgatgaaaga aggaaaataa catggaaaat tttaaaaaaa gcggaatgtt
    40861 ttccgtaatt gctgctctag gggctaatat tctagttgct atcagcaaat ttgtcggcta
    40921 tgcaatcagt ggcagtgccg ccatgctaaa cgaaagcatc cacagtatcg ttgattgcag
    40981 caatcagatt ttgctgttat tcggtgataa acaagccaat aaaggacaga gcgagttgca
    41041 tcaatttggt gaaggacgag caaaatactt tttcagtaca atcgtcgcaa tgatgctttt
    41101 cttcggcggt ggggcacttg gggtgatgga agcttttgaa aagttgacgc atccatccca
    41161 tgaagtgggt aatccgatca ttgttatagc aatactgtta tttggtttgg taatcgaagg
    41221 aagttcgtta cgcgtggcaa tgaaagaaat caaagaattg aatactgaaa aactttccac
    41281 gatgcgcttt ttgcgcgaaa gtcgacacag tgaaatactg attattttta cggaagactt
    41341 gtgtgctgta atcggtttgg tcttggcttt agcaggaaca atattgactt atgcaaccgg
    41401 gattgctgca tttgatgcga tcagcggatt gctgatcggt ttcttgctga tgggagccgc
    41461 cattttccta gcaaaagaat tttatagtct gatcatcggt gaaagcgtga cagcaagcga
    41521 tttatcaaaa atcaagttag cttttgaacg tcctgagatc agtcggctga tcgatataaa
    41581 aacagttcat ttaagtccaa cggagatttt agttgcagca aaagcagata tcgttggtaa
    41641 caaagagaat gaagcttact cggtcatcaa tgatattgaa aaaaatatgc gtcagtctct
    41701 tcctgacaag aagatgtata tatacattga aacagataaa tatgacccaa attattctcg
    41761 taaataaaac gtttattcat gaattgaagc aaaaatgaga aaaatataat cttgttttta
    41821 aataaaacgg ctacaattta gcgaatttat gttacaatga gtccgctgtt tatttgttgt
    41881 aattaaagga gatattttaa tgaacaaaaa gaaaagtgcg ccatggcttc aagctttgca
    41941 tgcagtgatg ccactttgta taagctatat accagtagga ttagcttgcg gagtattgtt
    42001 gcaaaaagtt ggatttgatc ctctcttatc aggactgtta tcgattctgg tcttttccgg
    42061 tggcgcgcag tttttagttg catctatgct tacgacgcaa gcatcatttg caacgacatt
    42121 attgatggtt ttctttttag aattacgcta tacattatta ggagcaagtc ttgccggttt
    42181 tatgaaaaaa gaaaagcgga cgtttttggc tgtcttttct caatcactga atgatgaaaa
    42241 ctatgcggtg aactacttaa agttttcaac tgacccttcc tggaataaaa gaaaggcttt
    42301 atatgtcaat tggttctcaa tgactgcatg ggccggtagc aatatgatcg gtaatttttt
    42361 cggctcggtg attcgagtag atgctgacct tgtccatttt gctttgacgg ccatgttcat
    42421 tttcatgttt atcatgcaga tgaaaagcgc actactgatc tttacaggtt tattctcagg
    42481 cgtattaggg gtcgtattca tggtattatt ccaaaatact ttcggattga ttgcagcaac
    42541 agtcattgct tcatttgccg gatttatgct ggagaaggca ttcaaaaaag aaaaagctaa
    42601 gaaactaaga gaccgcggta aagatgtcaa tgagccgctc ttcaacttcc cggaacagga
    42661 ggccaatcac catgactaaa ctatatttgc tacttttagt tgcttgtctg ttcatcgtgg
    42721 catatatccc gcgcttgttc ccgatgcttt attttactca tcgaaaagtg ccatcctggt
    42781 tcagtgactg gatgaaatat gtaccggtgg cattatttgc ggcgttagct tttaaagatg
    42841 ttttcattac tcatgaacat ctggatattg cttggaatat caaaatagct gcaatgattc
    42901 tagtagcagg cgtggcttac aaaacacgtt cgatggcgtt gtcagttttg acaggacttg
    42961 cgtctgtctt tttgctgtct atgctttaaa ctgttttatt ttattaaaaa cagagattgc
    43021 gacataagtt gttcaaactg atctatccga actgcatttg caacagtcaa ttctggatgc
    43081 aagtttattc gtagggataa aaaagattag tgttggctta tgatgcaagc tcttttttat
    43141 tttaggaatt agagagggat ttgtccttct atgatttttt gctataatag ggaagatgtt
    43201 tattttatga aagaatagtt gagggaattt aaatgaataa aaaattgatg caaggaacat
    43261 tttggctaac ctttgctaat cttctatgta aagttttagg ggtagtctat ttgattccct
    43321 ggctaagtat gatggggaac aatcaagatg gtatgcttgc tacgacattg tataatgttg
    43381 gctatcttcc ttatggattg ttcctgatgc ttggtacagt cggatttcca aatgcgattg
    43441 caaaaaaagt agctgtagcc acaaaagaag gagataacgc tgcttgtcgg ctgattttta
    43501 gaagtacgat caatatcatg tttgtcatcg gtatcgcctc tgctgcactg atgtatttat
    43561 ttgctccttt actagccgga atcagtccga ttgctaacgt taataatggg atactagcta
    43621 tcagaagttt atgcccatct ttgattgcta tcccaattct tagtgcaatg agaggatatt
    43681 tccaaggaaa aaatgatctg cggccttatg gaacttcttt gattatcgaa caggctgtgc
    43741 gagtgatcgt tatcttggct ggtacttatt acttgcgcgt attgactgac ggaaccatat
    43801 tagaagctgt attgatcagt acagtcgctt ctttcttcgg tgggttagct gcgattatcc
    43861 atatgtatat cgtcggacgc agaaaagact tcttcgaact taaagatttt ttgatttcca
    43921 gccgttattt cgaaagagaa aaccgatctg cctctgtctc tatcattcgg gaaacactac
    43981 cgtttatttt tgtcggctca gtcattacta tcgttcaaat gatcgaccaa gtaacgatga
    44041 aaccactgct tcactttttc cgtccagaga tcgcagatca gcaactggaa ttcttattca
    44101 gccgtgcttc tgtcaatcca aataaattga cattgatcct gatctccatg gtaggaacag
    44161 tagctataag cagcttgcca atattaagca cgatgaagaa aaaagatcgg atacaaatcg
    44221 aaaaaacagt aggagatagt ttttcgattg cgttattgat tcttcttcct tcattgactg
    44281 gaatgtcttt attagctgga ccactataca cattgttttt tggctatgat cctgaaagtg
    44341 tcggatattt ccaaatggct ttgctagctt ctttgttttt ctctttattc acgatcctat
    44401 ctacgatgct tcaatctttg aatcaccatc gttttgcgat ccgattaact gtagaagcaa
    44461 ttatcctgaa agtcatcttc caagtaatcg gattaggatt agttggcgga tacgggatga
    44521 gcttatcaaa tggcttagca ttcggtattg tctttgttcg cggctatcac tttatgtgca
    44581 aagaataccg aatagcacct ttagcaaaga tcagcaattt tttcttaaaa actttccgct
    44641 ccaccctgat tatgcttgca gtatgttttg ccgttttctt tttgctgaat cagcgattgt
    44701 caatggaatc aaaaagctat gcaatgattt attgtgtggc tgtaggaagt attggcggct
    44761 tagtattttt attttctcaa ttcggaaaaa atgggtttcg aatgttgaaa aatgttaaac
    44821 atcatagcag aagcaaagaa taggttaact aatcgttttt tgctgtcact tgaaaaacgg
    44881 caactcgtat gattacgctt gtcgtttttc tattttccaa ttttagtttc atatctaatc
    44941 ttacttatga tatagttata aggtctggaa aaattctttg aaacgaggaa attaaacaca
    45001 tgaaacttgc agtagttaca gatagttcgg catatctgcc ggaacgtatc aagaaccatc
    45061 ccgacttatt cgttattcca atccctttga ttatggatgg gaaaatttat aacgaaggaa
    45121 tcgatatcga agcggatgaa tattatggac ttttaaaaaa cagtaaagat tttcctacta
    45181 cttcacaacc tgtcgtaggg gaagttttgg gtttatatga ggaattgaaa gagaaagggt
    45241 atgacacgat tttaagtatc catctttctt cagggatttc tggctttgtc aacacattat
    45301 ttgcgatgaa agatgacatc agcggagtaa cggtcattcc ttatgactct aagatcacta
    45361 gtatgccgat gggacacatg gtagaagctg ccttagactt aaatgatgaa ggtcagtccc
    45421 ttgatgaaat acttgcacat atcgatcgaa tccgagataa tacctacgct tatctgattg
    45481 tagatgattt gaacaattta gtacgaggag gacgtttgac aaatggtgca gcgctgattg
    45541 gcagcttatt aaaaatcaaa ccgatcctga cattttctga agggaaaatt gttttattcg
    45601 aaaaaatccg ttcaagtaaa aaagcatttg ctcgagctga agaaattatt ggtagaagaa
    45661 ataacgaaat acaaccgcca gtcaaacttt acgtgataca tgcaaataat ttagaagtag
    45721 cgattgcgga gaaagagaaa ttgcagaaaa aatatccaaa tgcagaaatc gaaattggtc
    45781 atttcggacc agtcattggt acacatttag gtgaaaaagc catcggcatt gccatttcag
    45841 cgcaataatt ccttttattc aaaaaacata ccaaaaatat tccaacatca tcttggactt
    45901 tctacatgtt actaatgagc gtgtaaaaga acgagatggt gtttttattt ctatcaatga
    45961 agctcttttt ctttgcaatc ctcacttcaa tcctctataa tgtcgcatat agtttagtaa
    46021 atgagtaaac tactaattta cttatttact aaaaataaaa ggatgaggag ttaaaataat
    46081 ggaaatacca acaaatttaa aacataaacc agtaatcgtt gtagaagact atgataaagt
    46141 tgatggaaga aatgcattaa atacggatgc aaaagggctt tcactgggcc ttgctcagtg
    46201 gaatgatcgt ggaaaagtcg atatctcagg caaggtatgg cgacatactg gagaaaaatg
    46261 gtcacgacag tcggaagaat taccaatcac acgtatttta gatttagcga tcttagctgc
    46321 acaaggaagt ttatacttcc aagatgctta tcgttatgaa aaattttatg atccagaaaa
    46381 tccagtcgta gacatcattg gattacaagg gaaccgaatg acggtagaag tagataccaa
    46441 aaatccaaag atcgatgaag acatcatttt gtattacgat acactacaaa aagacggaga
    46501 actgattggg gaacgattcc gtattttaaa acgtctttta gatgagctag gatattaata
    46561 gacagagatg atcaaaaggg gaagagaagc atggagaatt tctcactaac agaaaaccga
    46621 accttttcac ggctagaaaa gcaaatgatc tggaagaaac cgaaaagcca tcggacaagt
    46681 gcagaagaat ggcggatcgc ctccgaaatc aaagggaatt ggcaagatcc tgaaatgaaa
    46741 atcagtaacg tacttttgga aggagatgcc gggtcgggga agacacaatt agccaaagca
    46801 ctatctgctg atctgcaact tccctataca aaagtgacct gttttgcaga tatggacaaa
    46861 tcagatgttt tcggagcctt attacctgta gtagattcta ataaggaaca agaccaagaa
    46921 ttactagaag ctatttacca aacagataca cttgaagctg tactgacact gatccagaac
    46981 cattacggca ttgatccttt ttctgctaaa gaaaaattag cagagctagt tcaaaggatc
    47041 gaagctgatt atccagatgc aatccattac agctattacc cttctgaaat cgttcgagcg
    47101 attgaaaaag gatatttatt agagattcaa gagccgactg tcatccgaga tgcctctgtt
    47161 cttgtggcac ttaactcagc gctcgaacca aatgggatgt tgaatttacc gacaggaatc
    47221 attcgtcgcc atccagattg cgtcattgtg atcactacaa atcgaaatta ccaaggaaat
    47281 cgcccattaa atgaatcttt aagagatcgg atgcaacatg cggaaaaaat ggatcttcct
    47341 gccttagaag tcatggcaga acgtgcgatg gcgaaaacta tgatccaaaa acaagaactt
    47401 ctcttaaaga tggcagagat tatccgtttg ttggatgaaa ctgcaaaagc taacgccatc
    47461 aaaggtgtag caggaatgcg ttcttatttt tattgggcaa atacctataa gcaaggacaa
    47521 gatttactcc agtcgattta tccaaaagtt ttgtataaat tatccactga ttcagatgaa
    47581 ttggcaattc ttgaacaagc tttgtctgac agtggattgc tactggaact tcaggacata
    47641 ttgagaaaag aaaaatgggg tcatcctcaa tctgagcata caaaaggaag aaccattagc
    47701 gccgaagaag caaatgaacg aaacatcact gaaaatgctg aagaaattct gcgcttagat
    47761 gaaaagaaat cgttgtctgc tgaagaacca aatgagggag aagagaaaca agaagaaaca
    47821 atagaaaaaa acgagattcc tcctcaaatg caaaaagaac gcagtagcga tatcgaagga
    47881 aaaaatcaaa aagaacaaca aacaggagat gattctcaag aaatgtctgc ttctgacatg
    47941 gaagcacatg ataaggaaat caagaagcaa ctgaataaag aagcgcgaca aatcatgaag
    48001 gaaacgattc atgaaaaaga aggtctcatc gttcaccgac cagctttcca aggaaaaacg
    48061 ccggaagcac gtgagctaca catgcaagta atgccaatag tagaatcact tagccggcaa
    48121 attttagagt tactggataa tgaacaaaca gagacgtacc aaaaaggaaa atacgaaggt
    48181 cagcggttca atgcaagcaa agtagcatat ggtgatttga gaaattttga caaaaagaac
    48241 ccgccacatg agcaaccttc tttagcggta gctgtacgga tcgatgaatc tgggtcaatg
    48301 atacgggatg atcggatcga agcggcaaaa aaagcagcga ttgccattgc cgaattttct
    48361 aagaaagtcg atatcccatt gttgatttac ggagatacag cagaccgttc gtcaagagaa
    48421 aagacttctt tgttttctta taaagaattt gaagacggat ttcaatggtt aaatgaaaaa
    48481 ttagtcacta tgaaaccaag gcaaaacaat cgtgatggtg ctgcacttcg tttagcagca
    48541 gaaaaattaa acagacaatc cgcaacaacc aaactgttgc ttattattag tgacggtcag
    48601 ccaaaagcgt tgccggatta tacaggcaaa aaagcaaaag aagatatcca gtctgttttg
    48661 aaagaatatg aacgtcaagg aatcctattt gtctccgcag ctattggcca agacaaagaa
    48721 gaaatcaagt cgatctacgg tgaaagtcgt tttgtagata ttactgactt gaatgaattt
    48781 cccaagcaaa tgattcaact gattgcccgc tatctatgat aaaataaagc tcaacgaacg
    48841 cacttagcag attcgttgag cttttcgttt ctagttaccg gtaacaagga tacttctaaa
    48901 atagaatcgg ttataatcaa gagggaccgt taaaggagtg aaacgatatg atacaagaac
    48961 aaaaatggtg gaaagaagca gtaggctatc aaatctatcc tgctagtttc aaagatagca
    49021 atggcgatgg tcaaggagac atcaatggga tccgtgaaaa acttaattat ttgaaagatc
    49081 ttggtatcgg ctttatctgg atcaatccga tctatcaatc tccatttgtc gataatggtt
    49141 atgacgtaag tgactatcaa gatatagaag agagattcgg aacgatggaa gattttgatt
    49201 tattgctaaa agaagcacat gaattaggga tcaaagtgat tatggatctt gtcatcaacc
    49261 atagttcgga tcagcatcaa tggtttgaag aatcgaaaaa atctaaagaa agcccgtatc
    49321 gcgattatta catttgggtc gacggggtag atggcaaaga accgaataat tggacatcga
    49381 ttttcggcgg ttctgcttgg gagtattctc atgaaactgg acagtattat ctgcatgttt
    49441 ttgcaaaaga acaaccagac ttaaattggg aaagcgagaa attgaaagaa gaactattca
    49501 atatgatccg atggtggttg gataaaggga tagatggatt tcgtttagat gcgatttctc
    49561 atgtaaaaaa agatgaatat tcagtaaaag ccacagagaa ccctttctca ccctttcaaa
    49621 atgtctcagg aatcgaagaa catttgaccg atttgaaaca tgtttttgaa gagtacgata
    49681 tcatgactgt cggagaagca agtggtgtca ctgcagaaga aggaccacaa tgggtaggga
    49741 aagacggtta tttcgatatg atattcgaat ttgatcatat ccatatctgg cagcaagaaa
    49801 aagaagggca attagatgtc cttaaattga aacttgcatt aagcgcttgg caaacttcat
    49861 tggatggtat cggatggaac gctttatata tggaaaacca tgatgttcct cgtgccgttt
    49921 cagtgtttgg agatactcgt cccgattttt gggctatgtc tgcaaaagca atcgctatga
    49981 tgtatttctt tttgcaaggt acgccattta tttatcaagg acaggaaatc ggaatgacga
    50041 atatgccctt tgaatcgatc gatcaagttg atgcagtaga ttcgaaaaga ctttataaaa
    50101 ggctgcttgc ggaaggtaag acaagagaag aagcattgga tatcattcgt gaaacaacga
    50161 gagacaacag caggacaccc atgcaatgga cttcggaaca atatgctggt ttttctacac
    50221 atgaaccttg gctgatcact aatccaaata ccaaaacgat caatgtagaa caacaagaat
    50281 atgaaccaga gtcggtcctg caattctata agaacatgat ccgcattaga caaaccaata
    50341 aaggtctgat atacggttct tataaagaat atcttcatga acatccacaa ctttatgtct
    50401 atgaaagata tttagaagat gaacaatatc ttattatggt aaacttaaca gaatcacttg
    50461 ctgactatga acttccaaaa gaagcagatc agtcctggac attactcttg tcaaattcct
    50521 ctagcggaga atttgaagct aaaggcatac tagcacctta tgaagctcgg ttatataaaa
    50581 caaacaagta aaacttcctc gttaaagttc attagttgga ctttgcgagg aagtttttca
    50641 gattgctctg tcaattactc atttcaataa ttcgctctag gaccaccgat atatttagga
    50701 cgagagcgaa gggctgtcac gtgagcttgt ccaagggttt tcaaacgagg tctgacaggt
    50761 acttggacat gtttgatatg cataccgatt gatgtgtcac cgatatcgat accggcttgt
    50821 ccaactacgt gttccacttc gacaggatca ttgaactggt caaaagcagc aacagaacaa
    50881 gcacctccag catgtagtgc aggaacaaca gagacaattt cgaaattttt tgcttctgcc
    50941 actgttcgtt ctactactaa tgctcggttc aaatgttcac aaccttggac agctagcgca
    51001 atttctttag gatccaacaa ctcttttaac gtacggatga tccattgacc aacttccgca
    51061 ctggaatttt ttccaatatg tcctccaacg acttcgcttg tgctgcatcc taaaacaaaa
    51121 agatcacctt ttttcaagtg tgcctcagcc aatatgtcat taactatttc agtcaattgg
    51181 tcttttaatt ctttttctga caacttcatt ttctaaaacc ttctttttca attaatattg
    51241 cttccgtgct tgaatacgtt gaagacttgc agttatagga aaggcaagtc ccattccaat
    51301 cagattttgg aagatgtttc ctggtataga agccactcca gccggccaat catataaaat
    51361 ccaaccggcg ataccatagc cgatgatcat aactaagctt cctaataaaa gccctaatcc
    51421 ccacatacga gtagaagatt tgctgaaaga accagcaaca tatccttgta acccgtggat
    51481 cactaatgaa aaaactgccc actgcggata tcctgaaatc aaatcgatca atagaccact
    51541 ggaagcacca acaactaatc cacccgttgg accataaaga aaagcagcgg tatagatccc
    51601 ggcctcgcat aatgtcacaa atccattcgt agccggtaca gggatcaaaa ttgttaatga
    51661 aagggcaact gtcaacgcaa tcagcatagc atagatcgtt aattgcttag ttttcatttc
    51721 tcattcctcc tttttgaata ccgccagacc agacacttcc ggtatgatcg ttcatcagca
    51781 cgccattaga aatacaatgg gcaacaaatt ttttactttc tgctactgct ttggtaaaat
    51841 ctgcccctaa cacaagattc gctgttattg cagaagaaaa ggcacaaccg gccccgttta
    51901 ctgttgtagt gtcgattttt ttatgagaaa atacctcata atgatcaatt gaatagagaa
    51961 gatccacagc ttcatctcca gccatccttg tgccgccttt gatcacaatg ttttttgttc
    52021 ctgaagcagt gagttcttta gcgagatgga tcatttctgt taacgaagag ggaagagctt
    52081 gaccagaaag taaagcagct tctgccaaat taggcgtaat catcgtaaca agtggaaaaa
    52141 gttcttcgat gagctgcgaa atatacaatt gattgatcac agcttcagtt tctttgaatg
    52201 ccaaaacagg gtctaaaatg attgggatat tttgttttgt ttttatgaag tctcgaacaa
    52261 ccatgattgc ttcacttgaa ttcaataacc caattttgat accatctaat gaagtcattt
    52321 tatcaatcga aactaactgt cgtttaagca attccaaaga tatagattcc agcataaatc
    52381 gctcattaat atctagtgcc cctatagaag tcaaggcgct tagtccgaat agaccaaaat
    52441 tctcaaaagt ttttaaatct gtttggattc ctccaccagc aaatggatca gaaccgccaa
    52501 ttgtcaagat tcttttcata acattttcct ccatgaataa gagtataacg aaattttcaa
    52561 aaaagaaaaa cagccaattg gcatattttt atctcatcca atttaaaaaa acaaaaagaa
    52621 aagaaagacc aaaatggatc tttctttcct taaatagtta ggacttttgt gattttaatt
    52681 ctttctcgat ttgaagccgt tgcactttca ttgtagctgt tcgcgggatt gcatcaaaat
    52741 cacggatgat agggacgttc aagcgaggaa gttcatggac ttgctcccac catcgattcc
    52801 aatccatttc tttatcagga gctaaagcaa taatcggttg tggagaatga tttttatccc
    52861 ttacaatcac tacttctgcc aaaaaatcta acgaatctaa taaaaagtct tcaatagcta
    52921 atgtactatt gatcgtttcg atcaaatcca cttgccgatc tttcaaaaat aggtggccat
    52981 gcttatccat aaaaccgtaa tctccgctat cccaccaatc gccataaaca ttttcctgga
    53041 accgtgcatc ttccttgtaa taagtcaaag cccgtccttt agacagtaat tgtatatgac
    53101 catctgtgtt ttcaggtagg acattcccaa ctgaatctgt aatccgagcg cttgtcatgt
    53161 cttccagtcc aacgcccata tctcttgcat cacttgtttt caaactctct agtgtatgag
    53221 ccttaagaat cattggtccg cattcacttt ggccatatac ttgaagaaat accgcatcct
    53281 gtgccatcga cgttcgcaaa aatgtcttca ttgtctggtt gtttatagca tcaaaagtgg
    53341 agtgatagta tcggataccc gaaaaagctt ctggatgctc cttagcagta aaacgccact
    53401 gaacaaagtt attcggatgg gtctctagtg caattggccg gtgagcttcc aacatatgaa
    53461 caacttttga actttgtgcg tttgctaaag gcatcatagg aaatcccatg gacatcaaag
    53521 aagagatacc aatattgaat ctggaatgca ctggagagat gtgaaaagcg attaatttct
    53581 tttccgaaat ttttgtgaaa actgtttttt gccatttcgt ccgccatccc atagaatgag
    53641 cagaatgaca aataagttta gggataccag ttgtaccaga agtatgggtc atataagaaa
    53701 tttcattttt gtctaaaaat gattgagaaa cagacaaagc aggttgttcc attaaataaa
    53761 gaatagg
//
LOCUS       DAPBBV010000018        52564 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.018, whole genome shotgun sequence.
ACCESSION   DAPBBV010000018 DAPBBV010000000
VERSION     DAPBBV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.018"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            241..825
                     /locus_tag="RD486_001284"
     CDS             241..825
                     /locus_tag="RD486_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663025.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            836..1081
                     /locus_tag="RD486_001285"
     CDS             836..1081
                     /locus_tag="RD486_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663026.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            1087..1809
                     /locus_tag="RD486_001286"
     CDS             1087..1809
                     /locus_tag="RD486_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663027.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            1940..2683
                     /locus_tag="RD486_001287"
     CDS             1940..2683
                     /locus_tag="RD486_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663028.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            2689..3054
                     /locus_tag="RD486_001288"
     CDS             2689..3054
                     /locus_tag="RD486_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663029.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            3070..3600
                     /locus_tag="RD486_001289"
     CDS             3070..3600
                     /locus_tag="RD486_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663030.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            3762..4070
                     /locus_tag="RD486_001290"
     CDS             3762..4070
                     /locus_tag="RD486_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663031.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     "
     gene            4066..4485
                     /locus_tag="RD486_001291"
                     /pseudo
     CDS             4066..4485
                     /locus_tag="RD486_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4622..5422
                     /locus_tag="RD486_001292"
     CDS             4622..5422
                     /locus_tag="RD486_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663032.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            5459..5641
                     /locus_tag="RD486_001293"
     CDS             5459..5641
                     /locus_tag="RD486_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663033.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            5752..6069
                     /locus_tag="RD486_001294"
     CDS             5752..6069
                     /locus_tag="RD486_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663034.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            6072..6304
                     /locus_tag="RD486_001295"
                     /pseudo
     CDS             6072..6304
                     /locus_tag="RD486_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6419..6898)
                     /locus_tag="RD486_001296"
     CDS             complement(6419..6898)
                     /locus_tag="RD486_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663035.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            7018..8355
                     /locus_tag="RD486_001297"
     CDS             7018..8355
                     /locus_tag="RD486_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDT7663036.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            8378..8905
                     /locus_tag="RD486_001298"
     CDS             8378..8905
                     /locus_tag="RD486_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663037.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            8892..9455
                     /locus_tag="RD486_001299"
     CDS             8892..9455
                     /locus_tag="RD486_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663038.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            9877..10614
                     /locus_tag="RD486_001300"
     CDS             9877..10614
                     /locus_tag="RD486_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663039.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(10631..11047)
                     /locus_tag="RD486_001301"
     CDS             complement(10631..11047)
                     /locus_tag="RD486_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663040.1"
                     /translation="MNKKRKLSVLITLVSILTILSVILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            11440..12687
                     /locus_tag="RD486_001302"
     CDS             11440..12687
                     /locus_tag="RD486_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDT7663041.1"
                     /translation="MNMKRNSLGMVLLASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPIENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKPMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            12955..15345
                     /locus_tag="RD486_001303"
     CDS             12955..15345
                     /locus_tag="RD486_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HDT7663042.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMMLSTLIMPFSAIRAEADVTKPT
                     SAKFIETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            15394..17229
                     /locus_tag="RD486_001304"
     CDS             15394..17229
                     /locus_tag="RD486_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7663043.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANRTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            17298..18161
                     /locus_tag="RD486_001305"
     CDS             17298..18161
                     /locus_tag="RD486_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7663044.1"
                     /translation="MSMKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNS
                     YKEKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGEL
                     VGEILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKY
                     FTDLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVG
                     DNSHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKI
                     VAKRRGMKNEE"
     gene            18151..19260
                     /locus_tag="RD486_001306"
     CDS             18151..19260
                     /locus_tag="RD486_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7663045.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKPETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVLGALASLKVLILLIKEFRKA"
     gene            19599..20399
                     /locus_tag="RD486_001307"
     CDS             19599..20399
                     /locus_tag="RD486_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663046.1"
                     /translation="MVEISKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETLKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLMGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYADDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            20487..21293
                     /locus_tag="RD486_001308"
     CDS             20487..21293
                     /locus_tag="RD486_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663047.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQFAEEKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            21525..22394
                     /locus_tag="RD486_001309"
     CDS             21525..22394
                     /locus_tag="RD486_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HDT7663048.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAINSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            22414..22761
                     /locus_tag="RD486_001310"
     CDS             22414..22761
                     /locus_tag="RD486_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663049.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            22774..24036
                     /locus_tag="RD486_001311"
     CDS             22774..24036
                     /locus_tag="RD486_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663050.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            24116..25492
                     /locus_tag="RD486_001312"
     CDS             24116..25492
                     /locus_tag="RD486_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HDT7663051.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMIIKLVNGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAESRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANSSSKEPSIEKKSTFALKLEKNKEEKEKQGAKTLEKLQAEKLEKVLKALDK
                     ADSEPQTSNNTNNEQPISSKTKPKTTDPKVSVNVTITTDKSEKKQVNGTTSPIMQKML
                     KAKKQVHK"
     gene            25489..26118
                     /locus_tag="RD486_001313"
     CDS             25489..26118
                     /locus_tag="RD486_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663052.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRTKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            26137..26616
                     /locus_tag="RD486_001314"
     CDS             26137..26616
                     /locus_tag="RD486_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663053.1"
                     /translation="MLELFEANRTGFNQKLEVGETIEYKDKNYIIIGIYNTRINRIGD
                     PRITSDLVCQSVNYSPDLTSRYKKYVLLEYRHKITDEIGVNNTRNIFKIGTVIPYSNN
                     EEKIFYQIYGIEKFEYEHVDLLVTYQMRLIEPWSQAEIDKAVKLNRLSKFNVLGNAF"
     gene            27118..27171
                     /locus_tag="RD486_001315"
                     /pseudo
     CDS             27118..27171
                     /locus_tag="RD486_001315"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27175..27774
                     /locus_tag="RD486_001316"
     CDS             27175..27774
                     /locus_tag="RD486_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDT7663054.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            27790..28266
                     /locus_tag="RD486_001317"
     CDS             27790..28266
                     /locus_tag="RD486_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663055.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSEDSKSMRDLLITYLNEHEFEQTKVKKKNKK"
     gene            28283..29185
                     /locus_tag="RD486_001318"
     CDS             28283..29185
                     /locus_tag="RD486_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663056.1"
                     /translation="MLFTLLGYLCLVLAFFGAIAIFVGQFQENNPIMRNIGIGIVIIS
                     LIVFGATKIFGSNDQQFGISGVDNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDDK
                     KASDDVLATIKPSQSQFEVFYTVKENNPVRKLTLVFNVDGEEYYKDVKINKASTKKIV
                     ESAKKEVATEESTTESSSTVEVELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQRINVTLFNAVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGSDLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            29258..29452
                     /locus_tag="RD486_001319"
     CDS             29258..29452
                     /locus_tag="RD486_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663057.1"
                     /translation="MVVNKEKVRKYVTLKIASVEYLEKRAKEEEKTRGKKVTVSELLE
                     ELIESDQTIRRAFTNRSVKS"
     gene            29557..29985
                     /locus_tag="RD486_001320"
     CDS             29557..29985
                     /locus_tag="RD486_001320"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663058.1"
                     /translation="MIIQKFDWKMKLGISLVILGFIIFLGIKAQKNQSTFETMSSQII
                     EECSKIYYCENKTEESNGFYYIDQPHDVVIKMESHEVNEWIQRSTNVSKKLERYSQTF
                     LSKVIFSNCKNEETSQRVASSLENLKFSVSKKEKFVDLRK"
     gene            30220..30807
                     /locus_tag="RD486_001321"
     CDS             30220..30807
                     /locus_tag="RD486_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663059.1"
                     /translation="MENNNDIRYFSIGERVTTVSELSKDYRDKEGTIISLKKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNDGSHSIEKAILVFPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITNKEAKVEDVLTVRELQSLIEYRNKQITNPEYLKKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDNFKKIYLKEIEKD"
     gene            30807..31706
                     /locus_tag="RD486_001322"
     CDS             30807..31706
                     /locus_tag="RD486_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDT7663060.1"
                     /translation="MWSVTLPFQPVSAPRPSARRNVADATNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQGLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            31706..32620
                     /locus_tag="RD486_001323"
     CDS             31706..32620
                     /locus_tag="RD486_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663061.1"
                     /translation="MNNNEKILHVLDSFETIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKKAMELNEDRRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPANSGIGIVLKAIDEEEIEDFIPAEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCEGYEVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     DARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNASNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKEAE"
     gene            32672..32887
                     /locus_tag="RD486_001324"
     CDS             32672..32887
                     /locus_tag="RD486_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663062.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLQQFWLNNFSYKDFIKEKANRLY"
     gene            33077..33331
                     /locus_tag="RD486_001325"
     CDS             33077..33331
                     /locus_tag="RD486_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663063.1"
                     /translation="MKKEELIDMFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLISDDVNFAHDVVGIQNHIDRENKRMGDGFLPRYSSL"
     gene            33510..34559
                     /locus_tag="RD486_001326"
     CDS             33510..34559
                     /locus_tag="RD486_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDT7663064.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGSPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     APNPTPAPAPSNEKVLNVPVIWQGNTMLCEGASLLEGLHYKGVATNQNLTSFVNYMPR
                     ANDNNPYHGYSGEWRYNVNGTYQGMMPDPVVKWAKNVGGNAVNITGSGTNGIKNEIRN
                     GNPVVTWITYNYASPQFKQMPWGRAVWNGHVVLVDGFKNGAYHVVDPVFGAKWINAST
                     YERAFNVTGMAVAVR"
     gene            34736..34966
                     /locus_tag="RD486_001327"
     CDS             34736..34966
                     /locus_tag="RD486_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663065.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEEEYKENIPENLQGS
                     ERYEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            34969..35226
                     /locus_tag="RD486_001328"
     CDS             34969..35226
                     /locus_tag="RD486_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663066.1"
                     /translation="MINEDFRSEQKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            35443..36318
                     /locus_tag="RD486_001329"
     CDS             35443..36318
                     /locus_tag="RD486_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663067.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            36328..37122
                     /locus_tag="RD486_001330"
     CDS             36328..37122
                     /locus_tag="RD486_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663068.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESAKELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            37151..38269
                     /locus_tag="RD486_001331"
     CDS             37151..38269
                     /locus_tag="RD486_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663069.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            38302..38622
                     /locus_tag="RD486_001332"
     CDS             38302..38622
                     /locus_tag="RD486_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663070.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            38877..39566
                     /locus_tag="RD486_001333"
     CDS             38877..39566
                     /locus_tag="RD486_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HDT7663071.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            39567..39770
                     /locus_tag="RD486_001334"
     CDS             39567..39770
                     /locus_tag="RD486_001334"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663072.1"
                     /translation="MSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNA
                     YIARLKRFIDKYKENSDKFSKDK"
     gene            39790..41418
                     /locus_tag="RD486_001335"
     CDS             39790..41418
                     /locus_tag="RD486_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663073.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            41469..41840
                     /locus_tag="RD486_001336"
     CDS             41469..41840
                     /locus_tag="RD486_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663074.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIFIVESELIAKVSLGLLIPI"
     gene            41925..42125
                     /locus_tag="RD486_001337"
     CDS             41925..42125
                     /locus_tag="RD486_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663075.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            42259..43485
                     /locus_tag="RD486_001338"
     CDS             42259..43485
                     /locus_tag="RD486_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663076.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            44269..45594
                     /locus_tag="RD486_001339"
     CDS             44269..45594
                     /locus_tag="RD486_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDT7663077.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            45587..45934
                     /locus_tag="RD486_001340"
     CDS             45587..45934
                     /locus_tag="RD486_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663078.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            46249..47106
                     /locus_tag="RD486_001341"
     CDS             46249..47106
                     /locus_tag="RD486_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDT7663079.1"
                     /translation="MEEKLIKKDEIIMGLLVPRANTYTIPLTKRQLIAERYQRITRAI
                     NREFWNSESDTAHSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQ
                     VIKNAFQEILPNSDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMG
                     GNWKATNPKKEQEAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEA
                     MGNWKFVENNSGGQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICL
                     EKVLKKIAL"
     gene            47126..47686
                     /locus_tag="RD486_001342"
     CDS             47126..47686
                     /locus_tag="RD486_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HDT7663080.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            48652..49419
                     /locus_tag="RD486_001343"
     CDS             48652..49419
                     /locus_tag="RD486_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HDT7663081.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            49445..49990
                     /locus_tag="RD486_001344"
     CDS             49445..49990
                     /locus_tag="RD486_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663082.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            49991..50557
                     /locus_tag="RD486_001345"
     CDS             49991..50557
                     /locus_tag="RD486_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663083.1"
                     /translation="MFEKRKDQFPNLEAESQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMEKENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGADDCVAYYTTAE"
     gene            50572..50820
                     /locus_tag="RD486_001346"
     CDS             50572..50820
                     /locus_tag="RD486_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663084.1"
                     /translation="MEGMDFLDHEDLVDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDDTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            50840..51079
                     /locus_tag="RD486_001347"
     CDS             50840..51079
                     /locus_tag="RD486_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663085.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEDLLRKTQRKGYPDKILKQIGYYM
                     PEERIEKEFCEVLFDSEQLLVLLTQNKLICQFENN"
     gene            51450..51731
                     /locus_tag="RD486_001348"
     CDS             51450..51731
                     /locus_tag="RD486_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HDT7663086.1"
                     /translation="MKVKNPTEKSRIQVGIDKNLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTKDMPVDVLDTDEKLEEWFDEA"
     gene            51721..52062
                     /locus_tag="RD486_001349"
     CDS             51721..52062
                     /locus_tag="RD486_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7663087.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     KKSDQIKRVYFPIAEWEKAGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSASDTKKL
                     NRFIEKLQRKV"
BASE COUNT        19965 a         7017 c        10509 g        15073 t
ORIGIN      
        1 taattgacag ctattgcaga acgataattt ccctgataaa aactacttct aacttcttct
       61 aataatggaa taattctagg atttttaact ttttttattt catcatctaa tataaacata
      121 taaatctcct ttttttattt gtatgacaag tttaccataa aaaaaaatta aaaagcgaga
      181 catatttatg ttgttgtgtt atcataataa cataaatatg tagagtgaga tgatgaaaaa
      241 atggatttga aacaatcgtt ttacatctgg ttatatcctg ataatcctat gtcaataatg
      301 gctgatattt ttgtagttag catcttattg tatttatttt atctaatttt ctttcacaat
      361 ttaatcgggt acatgattct tgattggaaa ggaatgttcg atatagaaag aaaaccattt
      421 gctaacaatc aaacctatac cgtcttcgaa agtggagatt gggaagaaaa tgaagttgat
      481 gtgatccatg aaattggatt agctttatca ggaatacaag atgctgatgt tttggtatca
      541 atgacaacgg atactggata caacgcttat gaggtatttt atcttatgta ttttatatgg
      601 cgtgatggtc aagaaattat caatggtcgt gctgaaaaaa caatcaattc taatactgaa
      661 atttcttttt gtatgggtga aggggaaatg attgtatata aagatgggtc agcaaacatt
      721 aaaacagcct ttggtgatat tgaaacaagt attaaggaac ttagggaata tgtgcagaac
      781 ccatataatt ttcaatattt agcaggaaga ataaatttag tttaggagta aaaatatgaa
      841 aaaaattata aatcaaccaa caaatcactt gataattgaa ggtgttattt tcgtaacaat
      901 gtattttact gtaggaaatg gcatctcaaa tacaatcatt caaaaaaatc cacaatacct
      961 attatttagt ctttatgctt ggattgtaca aatggtttgg gtttccatat tgatgctgtt
     1021 gttttattgg atagtacggg ttattctttt attgttaaac aaaagaaaaa aggataggtg
     1081 aataaaatga aatcaactaa attgaaggtt gtattgttat cgacagcagc attaataacc
     1141 cttacagcat gtggtacaac taatagtgct aataataaca aagacacaaa gtctagtagt
     1201 acgatggtta ctaaaaacag cactacatcg gcatcaacaa caatgtcttc aatgactgaa
     1261 aataatgctg aaaagtatca aaaatacgaa gacattaata aaggtcaaaa gccggatgaa
     1321 gtttataaca actttattaa tacagtaaaa aatgatgaaa attatgggaa tgatccattg
     1381 caaaataaaa atctgactat cgttctttac aaacctgatt gtccagattg tcaaaaagca
     1441 gaatcaaaaa tcatgcaaga aataaaagaa ggatttagtt atgctccaac attaatgcat
     1501 gatattacca taaataaacc agcttacgag tattacgcag ttgctgtaga tattactgat
     1561 ggtgtacctg agtgggtaca aaacattcct ggtctggctg atgagaacaa tcaatatcat
     1621 acgccaacag ttgcagtagt aacaccaaag aaagttaacg gcacactata ctgggatgta
     1681 atgggaatga caacaaatac aactgatgaa atgattgaaa gtacaactaa atattatatg
     1741 gatttgggag catataaatt atatcaacaa tcagagcctg ttatggacga tcaatccaaa
     1801 gttaaataga tctttagggc gtaagcccta tttttttaaa attaagtgat aacaaataaa
     1861 tgatttctga aacaaacgtt cttactcaac tactcgaaac acacaagcta attaactaga
     1921 ttataaagga gaatgcgtaa tgaaagaaat cagtgcaaat gaagctcata ttccgcaaaa
     1981 gaatcaggtt ggtatatata aggtgcttca tggtgaagga atttataaaa tacagttact
     2041 taccggttac aataatggtg caaatgggaa gtggttaaag gcaacaagta ttcgtgaact
     2101 tagaagtgaa gtagaaaaaa ttaggcttgg tctcacaagt gaagaaatag ctaaactgaa
     2161 gggaaataat tcttttgtaa ttgaaaaaga aaaggaaaaa catctacttt atcgtgagct
     2221 gaaaattgaa gaatactatg aaattgattt acctgaaaaa ttaagaatta ttgatcaacg
     2281 ttcagaagaa aaatggaaaa ctgaaatata tccaagctta aatgactaca agacatcagg
     2341 aaagcccatg tataactaca caggcttttt aacctacaca caatacaaat atgcctttcg
     2401 caaattaaaa ggcattaaac aagctgaaat tgccctgtat gagatgaaaa aagtggatag
     2461 attgaaattg attcaagatt tagtgcaaaa tacatggaat caagcgattg tcgagctaga
     2521 aaaagaaaat gggaaaattt taactaataa atatctgatc gtaaatgaaa ttgaagaatt
     2581 aattggttta ttttcatgtg aaaaaggtga agtcttcttg aagtcatcac caacctattc
     2641 aattttggac agtccgtatc agtttataca ggcaaggaga tgagttagat gtctagcttg
     2701 aaagatgact atatccaagc aaaacaagag tatgaaaaaa tacagatgtt gaaatctgag
     2761 aaagtcgaat tatttttaac acaaaaatta gcagaggatc atattgctaa cttagatgct
     2821 aaaactttag aggaatatga tcggcagttt aatcagatac atcacaatat cattttgctt
     2881 gttgagcagg caaagcgaag gtttgaaaaa gcggaatatg atctattaga tcaaggaatt
     2941 gtatgcttgg ataagggatt gcgaagatat tatggtgcag agttaaaaaa gcaaaatgta
     3001 gatagaaatg cactaaaaca tgaaatctta gaattgataa tgcaacgaat ttgaagggat
     3061 agaaagcaaa tgtcacaaaa cattagtgct gtaaaacaat taatagaaga agatttagag
     3121 accacagttc agagattagc ggaacgaatc cattttgcaa attatcaaac catctctaac
     3181 tggtcaagca ggaacagaaa tccggaagaa attccaatga aattttttta tcgaatcgga
     3241 aaagaatatg gtgttgatcc gataaaaatt ttcgagaaga ccatgattta ttactatcat
     3301 ggaacaccta acgaagtgtt agaacatctt ttggaagagg caaaagaaaa atcatcaata
     3361 ttagagctat cgcaaaatga caaagttatt caagtgaaat gcgttgatcc aacaggaaag
     3421 attattgtcg gttttgatat tgaaagaaaa tccaaaatag attttattac acaattaaaa
     3481 aagataaata atttagatat tctaacgctt agaccagatc atgaacagtt gtttatgagt
     3541 tttaaaaaac aattgaaaga aatacaaaaa agatataaca aggtgtttcc taatgcgtga
     3601 aaagctcaaa gaaatcagag ttttttggat aattaacaaa gaatgtatca tcttatatac
     3661 tcttggattt cttagcatga tcttgttttg gtggttatat ttaaaacagt aattggagag
     3721 ggtcaagagg atttttatca agataaggat gtggaaactg catgtggaat aatagattaa
     3781 aaacaggatt gttattaata gttatttcct gcgctatgat gattggtatg aggatacaaa
     3841 gggaacaatc ctattttgaa gtttctgcta acaacgtaat agaaaaatgc tattacggtc
     3901 aacattattg gagtgaggaa gtcagagaaa atatagatcg tgaatatgtt caaagaattg
     3961 tttgggatgc atattctatc aaagattatc ctaaaagttt aacgagtaga ttattttaca
     4021 gtgaaaaaga taatcaaaaa ctctcagatt tgatgatgaa aaaagtatga ctattattac
     4081 gaaagagaaa cagagtgcta tattcgaggg gaaaaagcct acaacaaaag tgactattgg
     4141 ggtgacaagg cgaagcgatt aactgcaaat tttagagtgt atgaatcaga gtttataaac
     4201 ttgacctttc ttaatagtgt ttttattgat tatgtaatta ctacgaaacg cattggaagt
     4261 tattcaagta cctacgcatc cttagttcca atgttaaact cgatgagccg tttcttaaaa
     4321 gaaagagaaa agaaagagct acagtatatc aaagaaatca tgccggattt tgaaatgcac
     4381 gaatggcaaa ttgctttatc agattggaaa ttggcgaata aggttcgtag aataacacct
     4441 tttcaagcca agcgcttttt gagagctatg aaatttgtgc aataaaaaaa gccaccagac
     4501 aagttgatgg agactaacac aattaccaac agttgtaatt gtgttagctt acaaattaat
     4561 tatggtgttt agtcaatccc aaattgtgaa atggcaccaa taattggaaa ggaaaaatga
     4621 aatgtctgaa gatttacgag agctgaagtt acgaaagaag cagtatgatc agtatttttc
     4681 cggtttgttg aataaacata ttgaagaagg acttgatcat gattttggaa aagatgaata
     4741 ttgtttatat tgcgaacgtt acaatgaaaa aatgtctgaa tatctacagc tgaaaaaaga
     4801 gatacagaaa ttagagaaaa aagtacatgc ttggaagtat aaagattcca tgtctggtta
     4861 tgttgaatct caaaataagc caagaaaaaa gaagcaagcg tatgttctaa agatggtaaa
     4921 tggggaagag ttaattgtat tagcgtacag tgaagaagag gttcgagaac tcgttgaaac
     4981 acctgtcagg aaaaaggttg aaacaataaa tgagatagac gacagccaat acaatagcat
     5041 ctatattgaa acaagtcatg gtggatataa gaaattagca actttcctta gaagttctaa
     5101 agttgggata atttctaaaa aagacataag tgctgttacc gatagttttt gtactttatc
     5161 tgttcctaaa gcttatttcc aatacgatag taaaagattt gaacgcttag agaaattctg
     5221 tagaccgtat actgtattga aaactaaaaa atttaataaa actaaaagag tttctataca
     5281 gttaccgact ggtcaaatct cattaggtga aaaagactat ctgataaaag taggaaaaga
     5341 gttaattata aaagtaccgg aacacttatt taaagaaaat tttgagatac gtgaaacctt
     5401 ggtatggaaa gaagaaaaat agtttggaag acatagaatg gtataagggg aaattgaaat
     5461 ggcagtaaat aaaatattgc aggtactaat catagacgaa tttggcggag gagaatggtt
     5521 tgatgtgcag tccatagact ttgaagaaga agtcgtagtt atagaaaata tttacggcga
     5581 agtatattca tattcgcttg aaggtgagaa tattgaggat ttacggttga ttggtgagta
     5641 gaaaaaaaca gaaatatcaa aatggagata aaaattaata gcatgtaaag atagtcatgc
     5701 ttgggttaaa aatgttaaaa ttcaaaaaaa tgagtcagaa gggataaaag tatgaaaaga
     5761 gaggaataca aacaaagatt aaacgaactg cttgaagagg acgaaacatt aactcatggt
     5821 tcgcctgatg aaattctata catgattgat aatatggtga tctttggtgg atatgaactt
     5881 ggtaataggt cagttgatca taatatttta gaatttgatg atgtatcatg ggaagaaatt
     5941 cttgattggg gaattttggc ggtacctgaa actaaaacct atattagtga cactatggtt
     6001 cctttttttg aggaattgga ttataaaaga cttcccaaaa atgaaaatca tatactggga
     6061 ggaaactaac aatgttaagt gacttattta ttttactgat ctatctaggt gtaagtgaaa
     6121 ttattgcgta ttttttgttt gtcattgcta attatggtat ttccagtgca atcgttcaaa
     6181 tgtttagatt accagtaagt gaactaaaaa aatgatgaga ttatcagcat atcttttaat
     6241 gtttttgaat gtggtcacgt taatctttgt agtaatcggt gtgactttcg atttaatgga
     6301 atagtgggaa atctataatg gaaaaaagag acacgaatga acatattttt tgaatcaata
     6361 ttgttgatgg tttttgcgat cagcgcttac cagaaatcta aaaaagagta atgattgttt
     6421 aatcatcact ctttttttgt agggaaattg aaatatgtgg agcttgtatt ggtttagtta
     6481 ggattgcttg gctataagga gctagttctt tatcaaaacc atcaaagtag gttttcagta
     6541 gcgatttaac tgatcgctca tcttgtttga tttggataat ttcagcatcc aaatcggttg
     6601 tgagatcagg agcttttgat gcgattacct gatttttttt atcttccaac tctcttaggc
     6661 tgtttaacaa gttgtaaaaa gaatcatttt gattgttcat tccaacgtga gttgcaattt
     6721 taacagaagt ttcgtccgta ttgtcatcaa aagaactcat tggaatatca agtagtaacg
     6781 aggatgtttc ttttactgac tttttcttta cagcattttt tgtttttcca tcttttttgc
     6841 tctttactcg agatgttttt ggagctagtt taggtaaatc acttgtttta tcagtcattt
     6901 attagctttt cctttctatt aatttatgtt attatattat cataataaca taaaaaagta
     6961 cactttttgg gggcgtagtt attgaaaaaa tctaagagaa agattgccac attgcttatg
     7021 ttaatggtgc aatttacagg gattgcaatg agtgtaatca caataaatcc gcaagtgata
     7081 catgctgatg ggatagctac ttatgatgca caatttaact gtactactga aggtagtggg
     7141 tcaggaacag atagcgatgg aaacgatact ggaagtggcg ctgtaacagg tgatgtagcc
     7201 aaaaatattg aagatattta caaatacatg aatggagaat atggcttatc aggtgctagt
     7261 attgcaggta ttttaggtaa ctggaaacaa gaatcaggta ttgatcctcg agcagtagaa
     7321 gggtattacg gagatggaca gagagaagtt gacttcatca aacaatttac tgatggtctg
     7381 atgggtattg gctatggtca atggacagct gggcgacata cagcattagt tgattggtct
     7441 aagaaaaata atggcggttc ttggtggact acagaagccc aattggactt tatgttcaaa
     7501 ggtgatgggg gattcgtagg aatattaaaa gattatgctt taaatgcttc tgatgatgtc
     7561 gtagaaaatg cagtaacttt tcataaaaac tgggaaattt cagctgattc cgaatcagct
     7621 gtaatagctg tacgtggtga aaatgcaaaa gaaatctgga agtacatgaa aagcaagggt
     7681 atggacggtg caaaagatga aagtaagatc aataaaatat ccggaggttc aagtaccgga
     7741 gatggatcga ataattcatc aagttcagca tcaggaacag tagaagatgc ctgtgcaact
     7801 acggatgacg ctaattctgg ttctggatca attgggaaag aaggaaaaat taacggtaaa
     7861 aaaggtcaag taatagcgaa tatgacttat gaagaagctt tgaaaaaata tgggaaagcg
     7921 atcacgctac caaaattcaa agaaccagat tggtcaactt caccttttaa cggaatatat
     7981 caaggtcagt gtacagagtt gacgtgggct tatatgagcc aattatacga tgggaatcaa
     8041 ccgactactg gaaatggtgg ttatgtatgg gaaagctaca aatcggcagg agcaaaaata
     8101 acgaacaaac caatcgtagg ttatgggttt agtgcttcgg atggatggtt atgggctgtt
     8161 ggagatgcag ggcatactgg tgtagttata gcggtgtttg aagatggatc atttctatgt
     8221 gctaacttta atgttccacc aacccaagct ccaacaaggg gagtttcggt aacgttgatt
     8281 gatggagtgg acggatcaga taatgtgcat ttctttagcg gtgtaggaaa agctaaattt
     8341 gaaatcgaaa aataaattgg aatgaaggac gatatagatg aatagtaaag tgaaagatac
     8401 aattatcatt tctttgcttt ctggtatgtt attagcactg cttgttggaa tcctattctt
     8461 caataagcag aatcaggaca tagaagctga aaaacacagt gtgcatattg aagataagct
     8521 gacattcttt aaagaggtta aaccaaatga ggtggatgga ttacggaaag atttagaaaa
     8581 tgatattcaa gaaatgttga atggatcagt tcaaaataag tttgcagatc aatcaggtga
     8641 agaatttttg agaaaactat ttattgtaac aggtaaacca ccaattactg ataagagtag
     8701 tgagaaagaa aaaatcgagt actataagcc ttttactttt aagctaacaa actttggaat
     8761 taagacatct agtagtgggt tgtatgaagc attgaccgat tttgaagttc aatacaatgg
     8821 aaaaaaagtg tatgatacca cattaaccat cacactaaat aatgataaga aagtgactgg
     8881 gggtgctttt tatgcaaaat catgaaatca ctactgctaa aaaggcgatc ggaatacttt
     8941 ccataattgt gatcctttgt tgtgtggtac tatttcaaaa gaaaaatgct tatgataata
     9001 atgtcaaaga attggaagac cttaaaagta aacaaatcga agtagtcaag aataaccaga
     9061 aagtgaaagc tatgcaggaa gctcaataca aagaattggg aaatgctgaa attaaggaac
     9121 aaagtaggaa attctttaat ttattttaca actggaattc atgggaaaaa tatacgaaga
     9181 atatgaagga aatacaaaaa gaatttcctc agatagtaaa gtctagtcct gttgatattt
     9241 ctggcacgat ggtaggcact ggtaatagtc caatatctag ctatactgct gattactata
     9301 caacaaatca aaaaggtaaa atggttgaat tgattacaca gacaagaaat actccaacaa
     9361 cagcaacaac aacaatttgg cgtggagtaa caagcatagg agaaaatcaa ttgttttatt
     9421 tggaggattt agatagctat gtaagagcag agtaaaataa aaaaagagct aacggtacca
     9481 acgttagctc tttgtgctga cgatgataac aaaacctacc gaaaaaggat tgtttcatca
     9541 caaacacaaa cagaaaagaa ttgataaaaa acccgaacct cagaattttt attaatcaat
     9601 tcatttagat tataataaat tgagctgaac attacaatac gtatatgttg taaaacgtaa
     9661 aaaaagtcaa aagtaaatac tttcttaaaa agtcaaataa aactattaaa gacaatatat
     9721 atggtttatt tgacataaga aaatggtcta gatgataatt gtaatataga attgtagact
     9781 taaataaagc ataaaatacc ttttatgata aggtatagct cttaatttta agcagtttta
     9841 gatataagat tgaaagtaaa gtgggggaga ataataatgg cagatcataa attagaaaag
     9901 ttattagaag aaacgtggaa tccaaaagaa tttagtgaat tttttatgga gaattttgaa
     9961 actgacttag cagtgattgt taaagatgct cttagagagc aagggtatcc tgaaactgca
    10021 aactatataa acattaattt tactttgtat actgaaaata aaggaacttg ggatttttgg
    10081 gctactttag caaataagga gttaagtgat aaatcagaca caggaattcg taactttttt
    10141 gaatcaaaca gagatgatta tatgtatgct aacaatcaaa ataaattgaa ctttagagta
    10201 gagtttgatg aaacacctga agaatttata gaaagacaac cgcctaaaga aaatgtagca
    10261 aaggtattgg aagatcgttg gaattcagat gaaatagttt caacaattag cgaactaggc
    10321 ggacaatatg aaccgctagt agaagcggtt agagaagagc taagactgaa taagtttcct
    10381 gatgttcaaa atattgatgt ttctcaaatt gaaataaacg tcaagatcac gaataaactt
    10441 gattatggta gttgggcaga tatagcatta gaaaaataca tctactcaac gttaaaagag
    10501 tttatcgaaa atagaatgga tatcatgtat ctacagcatc cacagtattt aaactttggt
    10561 gttgaaatag ctacacctct tgaagaatgg aaaatggagc aagggcttga ctagcctttg
    10621 ctccattttt ttattttaca aatgaataca gttcgtcgtt tttaccaaga atgattgttt
    10681 gcccaacttt gagattgtca ggtgatcctt cagcggtttg taaggagaac gttccattga
    10741 acttatcgga taccgttata ggtagcttta attctgatcc ttcctcatct ttgagaattg
    10801 ctgtttttcg ttcatcaaaa taaacagtct ttattaaata atttttcgta gtgatctcag
    10861 cagatttgtc tttttttgta gtagtaccag tttctttaga attagaggta ttttctacga
    10921 ctattccatc tttggcattt gagcttgtgt ttatttgatt gaatattttc agcgacaaga
    10981 taacgctaag aatagtcaat atagaaacaa gtgtaattaa tactgataat ttcctttttt
    11041 tgttcatttt ttcttaacat ccttttttgt tttgattagt tagatattcc ttatctaaca
    11101 agccttttta ggctattaaa tgaagataaa ccccaaaaaa atattgcaat tatgacagtg
    11161 caatggtact attattatac aataaatttt gcgaaagggg taggtctaaa tcgcaaacaa
    11221 aaagaaattg aacctagaca aatacaactt gtataccgca agggaagcaa gtttgatttt
    11281 gggtaaaggt agaaattatg ttacaaacat aatcaactat tatccaaatc gtttgcctaa
    11341 aggttcgttc aagaaagtgg gtgacaaaac ctatattata acggaagaag gaatagaagc
    11401 attgcgatca caaacagaaa ataaaaacaa aaagaaggaa tgaatatgaa gagaaattcg
    11461 cttggtatgg ttttattggc atcagctgta cttgcggggt tatcagtacc agtaacctca
    11521 catgctgatg aatggactgc aaacacaccg gatcaaatcc aaattacaac aggacaatca
    11581 agttatgcgt tcaaaaaagg agatactatt tggtcaactg tagagaagct taaaagctta
    11641 ggttacaaga ctactgttgc tgagtttgcc gaattgaaca atgttgattt ggcaaaagga
    11701 gaacaacgga ctatcccgat tggacgaact ttcaacatca gtaaagatac attaacagtt
    11761 aaggaagcag atggcgaagt agttagtcaa actgttcaaa aagataaacc tgatcctatt
    11821 gaaaatacgg agcaagagaa caaaaaatcc gagactacaa aagaatcgga accaacagca
    11881 aacacttctg ataagacaga aacaagtgct tcaagtgttg atggagcaag ttcatctaat
    11941 acaaataatt ctacaagtga gaaagaagca tcacagggaa caagtgaaag tagcactacg
    12001 gaagctgata ctggaacatc aacaaataac tcacaatcaa catcaaatga tgcaaatgaa
    12061 tcaaccagta catcttctag tgatcaatca caaacaggtt cgagtgatga aactgacagt
    12121 tctacttcac caagtaaacc cgaacaacca actaatgttg tgctaggcgt tccatttatt
    12181 agtcaaggta acacaatgct ttgcgaagga acatctttgc tagaagcgtt acattataaa
    12241 ggtgttgcaa caaatcaaga tttaatgact tttgttaaat caatgccact atctcctgac
    12301 aataatccaa ataatggttt ttctggtgaa tggagacaca atgtggatgg aacttatcaa
    12361 ggtatgaatc cggctcctgt agtttcatgg ggtgttgcta atggcggaaa tgttgtagat
    12421 atttctggtt catcggtaca aggattaaaa gatgagattg taaatggaaa tcctgtagta
    12481 gcgtgggtaa cttatgcctt tgaacctgct caacataaac caatgttttg gggcgatgct
    12541 atttggaatc gacatgtagt agccgttgat ggatttaaag acggttttta ccatgttgtc
    12601 gatcctgtgt ttggggcaag ttggattaat gcaggatcat ttgaaacagc atataacgta
    12661 tctcaattag cggtttcggt acgttaataa aagatatcgt ttatatacta agtagttata
    12721 tagtctttat ttgtccttgc ttaactactt agaaaacttg ttgctcatgg tgggtagaac
    12781 taaaaggggt gatgctatga atactagagc gttgaaacag cttgctttca acgaaaaaaa
    12841 tgattaatag gtgtggtgat tttaacttag gaatgggcgc gaaggtcatt accacaccga
    12901 catatcgtgg ctcattttct tcgcctaact ggtataaaga aggagtaacg agagatgaag
    12961 catgaaaaaa cgataatttt aaaatcaaaa ataatttatt gttttgcgac tttagtaatg
    13021 atgttatcta cgcttataat gcctttttca gcaataagag ctgaagcaga tgtcacaaaa
    13081 ccgacaagtg caaaatttat agaaactggc gtaaaaacag acggttatat tagggttaat
    13141 atgccgaatc atccaaatga atggatgatt tcaagtcaat ttaaagattc tcatggaaat
    13201 attggatatt gtatggattc agaattgcca tccccaacag gaagtggagc cggaagcttg
    13261 aagtacaagg gagctggcag tgatgagttc tatcgtatgt ttaaaggtgg ttttccatca
    13321 aaaacagcaa aggaactggg tgcaggaaat gatacagaag catggtatgc aacacaatta
    13381 gtttcatggg ttttagccgg aaactttaaa gtttcacaga ttgtatggtc acatccaaac
    13441 cataccgccg cagaaacagc tcgtgtaaaa aaagcatttg aaaaaattta tgactatgct
    13501 aagaatggaa aagatacgcc caacactgag ttttctatca cagcttctaa gacagctgac
    13561 gaaggaaaat atcacacttt cacatataaa acagcatcaa ataagactgg taatgcgaag
    13621 ctcactttta catcagcaaa accagctggt atgaagattt atgatgcaga tggtaaagaa
    13681 attactaaca acactgtgaa attaaattca agttttacta ttaaagtacc tgtgactaca
    13741 ccaagtggta ctttgtcatt taaaggtact gctaatgtta gcacaaccaa tccttttact
    13801 tttgatggac gaggtgtgta tcaagatgcc gtagttatga tcactacttc agaaacaaag
    13861 gactctaaat ctttgagtgc taaatggaca agagctgttg gtcaggtaac agttaagaaa
    13921 gttgatcaag atggaaatgc tttaaaagga gcggagttta ctctaactga caataacaat
    13981 gctaaatctg ttaagacaac cggagatgat gggttagcta cgtttgattt gcaacaaggc
    14041 ttaacataca gcttagaaga aacaaaagtt cctgaaggtt atcaaggttc atttaaaaag
    14101 gatggtatta ctgttaatac cgatggacaa gaatttagtt acactgctac gaacacaatt
    14161 aaaaaaggta aagtaaaagt taaaaaggtt gaccaagatg gaaaaccatt agctaatgct
    14221 gaatttacct tgacggatga ttcatcccaa acacaagcag aaaaaacaga tgaaaacgga
    14281 cttgcaagct tcgatattgt agcaaacaag acctacagcc ttgaagagac cggagtacca
    14341 actggttata caggcgtatt caagcaagaa ggaattaccg ttaaagatga tggacaaact
    14401 tttgaatata cagctacaaa cactttgaaa aaaggtttag taaaagttca taaagtcgat
    14461 caagatggaa aacctttggc aaatgcagag ttcactttaa ccgatgaaaa aggtgcaaca
    14521 caagtagaaa aaacagatga aaatggactt gcaagcttca atattgtagc aaacaagacg
    14581 tatagcctag aagaaaccgg agtaccagta ggttacacag gtgcatttaa gcaagagggt
    14641 atcaccgtta aagacgatgg gcaaactttt gaatatacag ctacaaataa tttgaaaaaa
    14701 ggtgtagtaa aagttcataa agtcgatcaa gatggaaaac ctttagcaga tgcagaattc
    14761 accttaacgg atgaaaaagg tgtaaaagaa gttaaaaaga cggatgcaac tggtctggct
    14821 acgttcaaca ttattgcgaa caaaacttat aacttagaag aaacaaaagt accaacaggt
    14881 tacacaggcg cattcaaaca agaaggaatt accgtcaaag atgatggaca agtctttgaa
    14941 tatactgcta aaaacacttt gaaaaaaggt gtgatcaaag ttcataaagt ggatgatcaa
    15001 gggaaagcat tagcaaacgc agaattcact ttgacagacg acaaaggtgt aaaagttgta
    15061 caaaaaacgg acagcaatgg cttggcaaca tttaatattg ttgccaacaa aacgtacaaa
    15121 atcgaagaaa cacaaaaccc taatggttat acagggaaat ggtctaaaga aggcatcacc
    15181 gttgctgacg atggacaaac ctttgaatat acagtaatta atcaccttgt acctgaaaca
    15241 gtaagaacag gcggaatcgg tacatcagcc ttccttcttg tatttctaat tgcaggattg
    15301 agtatggtgc tactgtatta tcgagaacag cacaaagcaa aataaaaaag tgttaatgga
    15361 aaagaagtaa atatgaaaaa agaaggctga cgtatgaaat caaaaaaaat tttttcaaat
    15421 ttaatgctat ttggtacttt gctaggagtg ggattgggcg caagctcaat ctcttctagc
    15481 cttggactag gggggcaagt agcatatgca caacaaaact ataattatca aggaactgga
    15541 acgattcata tccataaagt aacaaatact aatggggatg ggaaccctgt ctcagatatt
    15601 gataacaaag ggaaagaaat agctttacca aatggtgtaa aacctcttga aggcgttgag
    15661 ttctcttatg tgaaacttac taaagatgaa gctaaatcct tgggatggac ggatagtgat
    15721 actacaaaag gtcaacatat tgatgatgct aaagcacgat tattactaaa caaaaaatac
    15781 agtgaagtaa gtagaatgaa gactgattca caagggaata tagacatacc tatacaagta
    15841 aatacagacg atttaacaga taacttgtat ttgattgttg aaacaggaac agtcaaaggt
    15901 gtagttgaag aagcgtatcc tatgattgtt aacgtacctg aactaaacgg atcagatgat
    15961 caatacttta attatgatgt acatgtctat cctaaaaact atttccaatt aaactcagca
    16021 gagcttgata aaaaagacga agatggaaag gctcttgccg gaactgtttt tgaattgcga
    16081 aaagatgatg gatctgatca ggttgttgga acttataaaa cagacagcac aggtaaatta
    16141 actgtggatg gtttggaatt aggtgactat tatttcctag aaaccgattt gggaacagat
    16201 gctaatagaa caacctattt actagatggt aaaaaattca aatttagcgt taaacgtggg
    16261 gagactgcta aagtagttct tgatgttacc aactacaaac gacctgtaat tactaaggta
    16321 attgataaag aaaccgttga tactggcgaa gatgttcaat atacattgaa accatcaatt
    16381 cctggtaata ttggtaatta cgaaaaatat gttgtcaaag atgttctagg tgcagagtta
    16441 acttatgatt catcagaagt gatcgaagga atgactttag atactgatta cagtatcgaa
    16501 cgtgacggac aaacgacaaa ctatgtcttt actgaatcag gtatggataa gcttcagaaa
    16561 caatttgatg caggggatcg cttctttaca attttgatga acgctcatac taatagtaaa
    16621 gctaaaatgg atacaccact taagaatgat gtttcaacga tctacaacaa tggatatgaa
    16681 cccgaagacg aaacaccagt tgatcacgct tatacaatca ttggtgatca ccaattcatt
    16741 aaaacagacg gagatacaag caaagcattg agtggagcaa aatttgtagt gaagaacaaa
    16801 attgatccga ataaagttac ttacctaaaa caagatccaa caacgaaagc tgttacttgg
    16861 attgcagata aatctaaagc tactgaattc gtttccggat cagacggtaa gttccaaatt
    16921 gaaggtttgc aatataccta tgatgtagat tttgataaac aaggtaatcc aacaatcaca
    16981 gataaaaaaa tcaatgatta tgctcttgaa gaagttgttg ctccttcagg atatacacca
    17041 actagaaacg atgttccatt tgtggtatcg aatgatgatg cttctagcga agtaacagac
    17101 atcaagaacc ttaaaacacc tgaaacagtt cgtacaggtg gaattggaac agtagtattt
    17161 ctagtggttg caggtgtggc aggaacaggg ctatatgttg tctacaaacg agaacaacac
    17221 aaagcttaat gaaataaaat tccctagagt gtttttggct ctagggtttc tttttaaaaa
    17281 gtgtgtgaaa agtaggtatg agcatgaaaa agaagaatat caagttgatc atcttaaaaa
    17341 ttgggatgtt gctatgttta ggagtaggtc tatatcctgt aattactcag gcttatacct
    17401 actaccaaac tcaacaaaca ctaaactcct ataaggaaaa atatgatgaa gcttctgaaa
    17461 aggagaatga agaagtcttc aagagatatt cagaagttaa taggaaacga aaagacacag
    17521 aacaaacctc agtcacgatt cctgaagata ataacaatat tccgtcaaat ggaaatcttc
    17581 agaaggataa attaggtgaa ttagtgggtg aaattcttat accaaagatt aatgtggatt
    17641 tgccaattta tgatggtgta aacgatttcc aactatcagc aggagcagga atattaaccg
    17701 gaactgatta tccaactggt gggattggaa accattctgt tatatcagct cattcaggca
    17761 ttcctaataa aaaatatttt acagatttag agttgctcaa acttggtgat aaatttttta
    17821 ttgatatttc agggaaaaaa cttgcttatc aagtagatcg gataaaaaca attctaccaa
    17881 ccgaatttga ggatttgctt cctgtggcag gaaaagatta tgtaacactt atgacatgta
    17941 cacctgttgg agataattct cataggttac tcgttagagg ggttagcata ccttaccaaa
    18001 aaagtattgt tgagaaagaa aagaagaaag aagatttaaa ggtaaaggcg cagatgaact
    18061 ggtatcctat cgtagttgta ggggttttat taataatagc tgtgatagtc attattaaaa
    18121 aaatagtagc aaagagacga ggaatgaaaa atgaagaata aaatactact ttttttgact
    18181 cttatttgca ctttggtttt aacaatttat cctgcaaatc agctctatca tcaattcaaa
    18241 acaaaagaga atgtggcgga aatccaagag aaaattgaga aaaaacaaac tccttcaaaa
    18301 gaggaagtgg caaaaaaagt cgaacaaata aaatcgaaca gcggtaacca aggattagac
    18361 aatactcaga aaacagataa aggagtagac aatactcagg aaacagacgg tggatcattt
    18421 gatattcgtg aagctgaagg aaaggtcaat ccatacacag gagatgtttt ttcaaaaaat
    18481 caaacgaaag attttgaacc atctacctat tcaggagcgg ttggttatgt ctatattcca
    18541 aaaataaatg tgctagagct tttgtttcta ggcgcttcac aggagcattt atatagaggt
    18601 gtggcacaaa tgagtgctac tagtctacct ttatcaggta aaggtcatca aacagtaata
    18661 gcaggtcatc gtggcggtta tacgtcacca caatttcttt atgttgatca attagtagcc
    18721 ggagaccaca tttatataga ttatcttggt gaaaaagcag tttatacggt tttccgaaca
    18781 gacgttatta gaaattacgg tcagaattca acactgactg atattcctga tttagatatg
    18841 ttaacacttt atacttgtca tccatatcct cagaactacg atcgtttatt agttagaagt
    18901 ctaagagatg aaaaagcaaa atacatcacg ccacaagtaa cagttggcaa taccgcatac
    18961 gctgatgcca ttgatagtga atccgtttca gataagccag aaactgttac atcttctaat
    19021 gatttatttg aggatgttga tcgtgccaac aaggaattag atggaaataa tgatcttaat
    19081 attccggaac aaggtagcgt agagatgcaa gacagaacgt ttgctgaaaa ggcaagttca
    19141 atatttacag gaattaccaa taaacatcag aaaatgcttt tagtcatttg gactgtatta
    19201 ggagcattag caagtctaaa ggttcttatt cttttaatca aagagtttag aaaagcataa
    19261 tgaagattat aaaaattgat agagtacagt aaaaagggat tgatactatt attgatctct
    19321 tttttatttt gaatagagct agattcactt ttaaataaaa taaaaactga tcttaattcc
    19381 aaagaaaaag tcaagaaaaa aatacaacaa atttttttat cagaatattt atcagaatat
    19441 tattagaaaa gataaactca aaagcttaat ttaatagggt tattggttgt atttagaaat
    19501 aatgtatgga aaagctataa agcaatagat aagatgtaga aaatcttatt tgtgaatgaa
    19561 aaacaagtca tcgtaaaata ttaataggag gtgtagtaat ggtggaaata tcaaaaacag
    19621 ctttagactc attagctaaa ctatttagta gcaggtttga tggtgcagaa tttgttgaat
    19681 atctaagcca aaacgaaagt ggaaaaactc tgatcgaaac actgaaaaaa gactatttga
    19741 atgaaaatga ctttccgaca tggacgaata ttgaagatgc tacatgggat gtagtgtgta
    19801 cgatatattc tccttgggta acgattgctg attttgtttt agataaaatt ggaggggata
    19861 cataccctga tgccaaatct cttgctacaa gtgactttaa aacgttctat ggttatctaa
    19921 tgggtctaat aggcaatgga atagatttga aagttacgcc aaaacaaaca cctgaagaaa
    19981 ttgaaaaaga aaaaggagag gttcaaatgg cttatgcaga tgacagagaa aaagtaaaat
    20041 tattggaagg taaattatct gaagaagaac ttggaaaaat ggtgcaagaa atcaatgaag
    20101 acagcaacta ttttcctgaa ttgaaggtat atcaaaacga cgaagatttc tttaatgaaa
    20161 tgtttagtaa tagtccatgg gaagcagtga gtaaaacaaa tttaggagaa tggaactttc
    20221 aagatgatct agttgcattt agcaatgatg ggtatttacg atcatattca gaaagtgagt
    20281 atagagctga attaaaaacg tatgaaacgg atattctgat gagctattta aatctattag
    20341 agagtggtca gggagagtta agagataaag ttgaagaact attaaaagaa gagctatagg
    20401 gattatttca acataaacac aagcagaaaa ctaccaaaca aaacgtacca tgcaaaaagc
    20461 cggttaaacc ggctttttgc tctattatga gaggagatca aaccatgagt gcaacaaccg
    20521 atatggcttt agaagcagta ataaaagata atacaggaaa tgtcgaaaat gtagaagact
    20581 ttagcgatat tgcaatcaat ctttcagcat ggatttcagc tgtaggagaa gaaaatatcg
    20641 aatttgagat caagaatatg gatgacttaa aagcaaaatt tccttttatc gcatcgaaac
    20701 taagtcaatt tgccgaggag aaatcgtgga atgaattagt tagtttttcc gaaaaaattt
    20761 atgatattac gcaagaagat gagtgtgttt catgggaaat gaataatcaa tacaagaaaa
    20821 ttgatgcttt cgtcaaatca cgtatagaag gaacagcttt tgagtttgaa ggtatagata
    20881 ccgcagataa ttggttaaat aaagaatcct ttattaaaag tatagcggat gatcttgaaa
    20941 aacaatggtc taaggaagac tatgcagagt acctaaaaac agaaagagat acagaggtga
    21001 aagaaaaact cactgaggta tgtttggatg aacatattga tcccaatatc gtaaaacaag
    21061 aagactatga agtggttatt gataaagttc ctactgattt tgaggaagtt gtaaagtata
    21121 tagttgaaga agcattatcg caatactctt cagatgagga agtggacgaa gaaactgttc
    21181 gtaccagagt ttggcaactg gtttttgatg acaaagatta taaatatttg agtgatcaaa
    21241 actcggttaa ttggagtgta cgattattaa ttgatcaaaa tgatattgaa taaaatagag
    21301 ctgaaaagct ctattttttt tgataaaaaa actagctatt tttttaaaaa taatttggtt
    21361 caaaatttat ttttttaact tgataatttt ttgccatcct tttttaaatt ggctatatat
    21421 caaggtttat agtggggata aataaaaata catttgacaa aatttacaat atagtttatt
    21481 atatatttat cttattatga taacacaata aaaggaatga tggtatgaaa aagaagaagt
    21541 ttagtcgatc gttgttagga attttagttt tagttgcggt tggtcttagt ggcaagggtt
    21601 actttcagaa taacagcact caggaacatg attttcagat caaaagtagt gttcaggtag
    21661 gtaataaagc agacagtgaa tcaaaagaat ttttagggat acgttatgat ccaaacaaat
    21721 atccaaataa tatcgtaaac attaatgatg ggaaatatac actgacaaaa gaagaccatg
    21781 aagcattatc agaaaaaggc agtcaaacct tttgggtaaa ttatgcagat ttagatcaac
    21841 ttggaagagc aggagatgtt gaagcgttga tcacctatga tgctataaat tctcactcat
    21901 ctaaaaatgt ggaacgtcca tctttcaaaa gttctgtcca tattgcagga gaatacaagg
    21961 atggagtatt tgatcaagag agagatactt gggtcggcaa agattcaaac aatgaaatca
    22021 ctcagctaga aggatataaa ggttatctct ataacaaaag tcattcatta gcatggtcgc
    22081 taggaggaga tatggaggta cacaatttaa cacttggaac gagagcgcaa aatgttggga
    22141 aaaatgatca gaatggaggg atggcttact cagaaacgat tgtacgtgat gcaatctata
    22201 aaaataagaa tgaaaaagta ttgtataaag ttgatccaat ttataaaggg aatgaattgg
    22261 ttcctcgtgg ttctcatgtc gaagctttct cagttaacga taatggaaaa acggtaaacc
    22321 ttaatgttta tgtatttaac aatcaaaaag gaatcaacat caactatcaa aatggtactt
    22381 gggtaagaga ttagaaattg agaaggtgaa gaattggaaa caataagcat caatggatta
    22441 gataaatcag ttgcaaatcg aataaaaaaa ggaaatggct actatcttct gaagaagggt
    22501 aaatattcag ttgctagaga gttagaaaca atgagtatcg tgtatgtagc taagaatcat
    22561 tttgacgtag aacaggctat ttttgatcca gattctgaaa tagggaaatg tgttgaatta
    22621 tcagagaaaa ctgttagtac aaaaggggcg atgatcattg agagagaaat gttagacgaa
    22681 atcagagtaa tcattcctaa agatacgcag atgtgtgagg acagcataag tgacgatgaa
    22741 ccaaaatcag aaagaaaata aggagatatt cagatgagcg aaaaatccat tgaattaaag
    22801 gaatataagc gaagcgatgg agaaaaatat tatcctgtag ccagtttttc taaatcagta
    22861 tatctggttg gacgtgcatt ggtagttggt gcaattggca tatatatttt gcattgggta
    22921 acaaaggttg tacaactgct tgtagatacc ttagtaagta ttcttgtctc gttaaatgat
    22981 gttaacggaa cagatgattt aggattaaaa gaaatgttta aagagttact caatgcgttt
    23041 tttcccaatt atttaagtta ttcatataat gtacaaagct tttttgcaaa gctacacttg
    23101 gtagacatct ctattttagt attagaagca ggaacggtat tctttgttgg atatttggtt
    23161 actttgatgt tcaggcatca ctatggagaa caaagaccat tttttgatga tatggaaagt
    23221 agaaggttga aaagagaagc tctagaagct atggatgtga agtatgatcc aaacaagatt
    23281 ataggagatg aaacgaacaa caaaaaaaga aaacgaaaca aaacgcaatt agaatccgat
    23341 gtgctatcaa cgcttaaaaa tatcaaaatt tctgttcata caagacgtga tctaagtgtc
    23401 aatgaagata ttcgagaata tatcgtaaaa atcccgcaac caaaagggaa gaaagttaga
    23461 gaaacagttt tacgacaaat tcaagattta gggtcgatcc tgacaagagc aacaagcgga
    23521 cgagccaaat ttggtgaaaa agaagatgaa gtttcaggcg attatttcat tttccgagca
    23581 tcagtaaata ttgaaagaga acgtaaggaa agagtaagta ccaaaaacaa agaaacggaa
    23641 agagcaacat cttcaatcgc agtttcaaat tcacaatttt cttttccaat caatctcttt
    23701 gccgataatt ccaaaaatat ccaaaaccaa accgaaaaag ctagaaaata tgccgaaact
    23761 caaaagcaat ctttagaact ttatctatct tctgctgacg tacctgcaag tctaacagat
    23821 atgcacgttg ggaatacatc tattgaatat ttgtttactt tatctcgtac cagaaaaatt
    23881 caactaagct caatgaaaga agaaattgaa acttacttgc atatatcagg tgtaatcgtg
    23941 cggatcaacg cagggcgtat tcaaattact ctaccattag gagaaaatga tcgtattcca
    24001 attgatgtac catcaatgat caatagcgtg ttttaaaaga catcacaaat agaaacagaa
    24061 aatacaaact accagttcac aaacagaaaa gtaccgagaa aagtgaggaa tagaaatggc
    24121 tatgaaatta ttagagaaag tcaaaaagag agccgaaaaa gctgaatcta ttttgctaga
    24181 taaagaacct aatataaagc ttaatggaaa attcagtgtc aatatgttga acacaaaggc
    24241 taaagacccg acagatgcta tttttggaat taagcctgat ggcacaattg ctcatttttg
    24301 catcagcgaa atgccacaca tgttggttgc aggaacgaca ggatcaggga aatcagtatt
    24361 actgaatgaa attcttgtta cagcaatgtg tcactcaacg cctgatgaat taaaaatagg
    24421 aattgtagac ccaaaaaggg ttgaatttgg aagatacaaa aaattgccgt tcatgttggc
    24481 tgatccaatt acagatatgg atgaagctta tgattttttt gaatatcttg tgatcttgat
    24541 gcatgaacgt tacaaactga tggaaaaagc agggttacaa aacatcacgc tatataacga
    24601 atatgccgaa aaaaatggat tagatagatt tccctatgtg atcttattag ttgatgaata
    24661 ttcacagttg gttggaacac ataaagaagt agaaggtttg attgttcaat taggacaaat
    24721 ggcaagggca gcaggtattc atgttatctt agctacacaa tctcctcgat caacagttgt
    24781 cactggtatt atcaaagcca attttccgtc acgtgtttgc cttatggtag caagtgattt
    24841 agaaagtagg atcgtattag atgaaggcgg tggagaaagc ctaagtccaa agggagatat
    24901 gattattaag ctcgttaatg gaagtatggt tagagcgcag ggagcttaca tcagtaacaa
    24961 agaaattgaa acaattttca atcaccttag aaatactatg ccagaaccag aatatgttga
    25021 ttaccgagca atcgtagctg aatctcgtgg tgagggtgga gaagacgagg attttggtgg
    25081 aattggtaaa gctcctgtaa gaaaatctgc taaaagaaat ttgaacacac ctttagcaaa
    25141 ttcatcatct aaagagccat caattgaaaa gaagagtacg tttgctctaa aacttgaaaa
    25201 aaacaaagaa gaaaaagaaa aacaaggagc taaaacacta gaaaaacttc aagccgaaaa
    25261 attagaaaaa gttttaaaag cattagataa agctgattct gaaccgcaaa cctcaaacaa
    25321 cacgaataat gaacagccga tttcatctaa aactaaaccg aaaactactg atccgaaagt
    25381 ttcagtaaac gtgaccatca caaccgataa gtctgagaag aaacaagtaa acggaacgac
    25441 ttcacctatc atgcaaaaaa tgttgaaagc caaaaaacag gtgcataaat gatcattgtc
    25501 agttcttttt tgaggtggct tacgccatat aaatatacag atgaagtagt tgtgaaacga
    25561 acgaagaaaa gagataaaaa agcggtacta actcctaaac agatgcttga tcatggcatt
    25621 ttaggggtga aggttttaga agtgaataaa ccgtttgaat caaatagtgc aagagaaaag
    25681 ttgcttggag ctgaagccga tgtcgcatat ttttaccatg acaaaagcaa gcatcaaata
    25741 gctattaaat tcaatccaaa atcggcatgg cggtatcaag caagagatga cttgaaacgt
    25801 aggaaactta gaccaatgct ctatccagaa ggaaaagaag catttgatag aacccacatc
    25861 gttcccattg gttttcatgg tacagaatca gataaccgcc tattagtagg ttggaacagc
    25921 aatcaaaata gagttcagat caataaattt gagaagaaag taaggaaatt caacgatcga
    25981 aaaacgatcc tatggtttgc agatatttgt aaacagccgg atggaacagc aaagtgggaa
    26041 gcggtgatat ttgacgaaaa tggtaaaaaa gtaatgtctg aaacatggca tgataaagct
    26101 aaatttgttt ggcagtagca gtagaggtga aaaagattgc tagaactttt tgaagcaaat
    26161 agaacaggct ttaatcaaaa gttagaagtg ggagaaacta tagaatataa agataaaaac
    26221 tatattatta tcggaatcta taacacgaga attaacagaa taggtgatcc acgtataacc
    26281 agtgacttgg tttgtcaatc tgttaactat tcacctgatc tgacaagcag gtataagaaa
    26341 tacgtgttat tagaatatag acacaagatt actgatgaaa ttggtgtaaa caacacacga
    26401 aacatattta agatcggaac agtgattcct tatagtaaca acgaagaaaa aatattttat
    26461 cagatttacg gaatagaaaa gtttgaatat gaacatgtcg atctgctagt gacgtaccaa
    26521 atgcgtttaa tagaaccttg gtcacaggca gaaattgata aagcagtaaa attgaaccga
    26581 ttatcaaaat ttaacgtatt aggaaatgcc ttttaaaaat cgcaatacac aaacagaaaa
    26641 ataccaaaaa attagcaatg aacgtaggta agaacatgac aataaataat aataacccta
    26701 aaaaatataa tgctcttgtc caatgctata tcgaaaacaa aattacaatg caagaagtcg
    26761 ctgatgaatt aggcaaatca aagagcctag tatcacacga ttttaagcac aatgtttttc
    26821 cgaacccgat tgagctgagg aaaaaatttc aaaagagagt ttatcaagaa ataggtaagt
    26881 ggattgatga agggaatgca attgaccctt taattgaaaa atatcctttt ttaaaaagca
    26941 aaaataaaat tcaaaggtta attcgtcaag gcgatattca agctaaagaa cctgttttga
    27001 caaccaatga tttggctaaa ataaatcttc ataaacaaat tattgaagac tttgaaaaaa
    27061 atctttcaac aactgaaatt ttaaaaaaat acaatattcc gagaggaaag ctaacatcga
    27121 ctctttttag agaatatgga gaatcggcag ttactaaagc aaaggaagta gcgaatgaga
    27181 gaaaaaaaca aaaatagtag tcgataccta gtagcgactg tagtttttgt ttgtgtattg
    27241 attttcctgt ttgatttttt gcagattgga aaaagcataa ttggaaatac attgagtgca
    27301 aaggaaatgg ttgctttagg tggtttgtat gaaggacact tgttcccgaa tatattcatt
    27361 tctatcgttt ctcatattaa cttgtaccat ttaatttcta atttattgtt cttagtagtt
    27421 cttgaagaag cactgaatga tcagtatgag tggttaacat tattgatcgt tttaatcata
    27481 tcaggatttc taggaagctt agttcctttt ctgctacaca gcaacatcgt aagtatgggg
    27541 cttagtggag gtatttttgg atggattgct ttatttgcga ttgcatacat ccgttttgat
    27601 agcaagaaac atttattact aagtgttttt gtattattga taatcggcat tttactggta
    27661 tctacttttg aatcaggcga gacgaacgtc ttgtcacatg taatcggatt tgtctgtggg
    27721 atgatcttgg gatttattct aaagaacgtt tcattgatca aacaaaagaa ttaaaaggga
    27781 gtgctaaaaa tgccaaaaaa aaaagaaaag aaaattccag tgtttttgtc tgtctcagaa
    27841 atgttatcac ttcaaatact gttaagaaaa aagattgaaa caatagacga agaagttaga
    27901 aataaaaggg ctatgtacga acaacgtgaa gcgctaagag aacgaatcca ctattttgat
    27961 gatatacaca ctaaaatcta tgaagcacgt acaaatcacg aagacgaaag caaattagga
    28021 ttagctcaac aacgaatatt tgaatggctg aatacgaata ctgagcaaga accgttaaga
    28081 gcaattagta atctttttga atttggaacg aagcattggt ttaacgctgt agaaaaggat
    28141 gctgacttac aagaagcgtt cgatacacta agcgaggata gcaaatccat gcgagactta
    28201 ttgatcactt atctaaatga gcatgaattt gaacagacga aagttaaaaa gaaaaataaa
    28261 aaatagaaag ttgtgatgta tcatgctgtt taccttatta ggttatttat gtttagttct
    28321 tgcttttttt ggagcaattg ctatatttgt cggtcagttt caagaaaata atccgataat
    28381 gcgtaacata ggcattggaa ttgttatcat atccttgatt gtatttggtg ccacaaagat
    28441 ttttgggagt aatgatcagc agtttggtat ttctggagtt gataatagtt atgctccaga
    28501 ttcattggga agagtagtga tagatggaac gtttgagaat gtaacgagct acaaaaatgt
    28561 ttcattgaca gtgaaagaag atgacaagaa agcatcagat gacgttctcg ctacgatcaa
    28621 gccgtctcaa tcacagtttg aagtgtttta tacagtcaaa gagaataacc ctgtacgcaa
    28681 gctaacatta gtttttaacg ttgacggaga agaatactat aaagatgtaa aaatcaataa
    28741 agcatcaacg aaaaagattg tcgaatcagc gaaaaaagaa gtagctacag aagaaagtac
    28801 aactgaatca agttctactg tcgaagttga actaccagat aaaattgatt ttgatcctga
    28861 aaaagtcaaa tcgtttgaat ctgtttctgg ttctatggca gatcggttta acactgaagt
    28921 tttcaaagct atcaaaactg ttaaattgga tactgaaaag caaaggatta atgttacctt
    28981 attcaatgca gttgaatcta tggatcagga taaaaaagtt acggttgcaa gagaactagg
    29041 gaaaagagta attggattgt atcgaggtac ggcaaaacca gattcagacg gttcagattt
    29101 gccagttcac gtagtttatg aagacggtaa agtttttgga gactctacag caaatgaagc
    29161 actaacgatt aaattagcta aatagccgga aaattataat aaacaagtgg tgtcacacca
    29221 ccatcgcata ggtgtgacac cttggagatg attactgatg gtagtaaata aagaaaaagt
    29281 aagaaagtat gttactttaa aaatagcttc tgttgaatat ttagaaaagc gagctaaaga
    29341 agaagaaaaa acaagaggta agaaggtaac agtttcagag ttgttagaag aattaattga
    29401 gagtgaccaa acaataagac gtgcatttac caataggtct gttaaaagtt agggtgatac
    29461 tatctttaat ttcaaccaaa tttctaatat atgatgaata gtttccttgt acaaaatatc
    29521 taattaagag ataaaagtta ggaggattca ttcaaaatga ttatccaaaa gtttgactgg
    29581 aaaatgaaat taggaattag tcttgtaata ttgggattta ttattttttt ggggataaaa
    29641 gcacaaaaaa atcaatctac ttttgaaact atgtcttctc aaattattga ggaatgttcc
    29701 aaaatttatt attgtgagaa caaaactgaa gaatctaatg gcttttatta tatcgatcaa
    29761 ccacatgatg ttgttataaa aatggagtca catgaagtaa acgaatggat tcaaagaagt
    29821 actaatgtat caaaaaagtt agaaagatat tctcaaacgt ttttaagtaa agtcattttt
    29881 tcaaattgca aaaatgaaga aacgtctcaa agagtagcta gttctttaga aaatttaaaa
    29941 ttttctgttt caaaaaaaga gaaatttgta gatttacgaa aataaactat cgaaagtagt
    30001 atgattatga tcttaaaata tcatcttaag agaagaatta cgattgttta taggatttac
    30061 aaaatgaata agtttgaaga gtgatttggt cgcagactag atcactcttt ttgtgtaaaa
    30121 aaactttaca cttatttttg agtgtgttaa gattttttat atagagtgac ggtttcttgt
    30181 cagagtggat gataaccatc aatattggag gaataataag tggaaaacaa taatgatatt
    30241 agatatttta gcattgggga aagagttaca acagtaagtg aattatcaaa ggattataga
    30301 gataaagaag gaacgattat ttctcttaaa aagaatcgaa gaggtgtttg gcaatatgtt
    30361 gttgatttag gggatggcgt tacagttgag tgtaaagata gtcaactgat cagaaatgat
    30421 ggcagtcatt ccattgaaaa agcaattctt gtattcccaa aagtatcaag caagattatg
    30481 aatgactggt tgcttggaaa atttggtgag tacaataaaa aagaaatcgc agaagtgatc
    30541 ggcaaatctt atccaacagt attagggtat ctaaaaaaga taacgaacaa agaagcgaaa
    30601 gttgaggatg ttttaacagt aagagaactt cagtcattaa tcgaatatcg gaataaacaa
    30661 ataacaaatc ctgagtacct taaaaaagaa gatggtctat tgaaacaatt ggaacaggta
    30721 aataaaatcc ggaaaatgca aaaggtagct cctttaagcc tagataactt taaaaaaatc
    30781 tatttgaaag agatcgaaaa agactaatgt ggagtgtcac tttaccgttt caacctgtat
    30841 ctgcaccaag accaagtgca agaaggaatg ttgctgatgc aactaatgac gtagcagaga
    30901 aaaggatttc aacctattat gataaaaagt atctcgatta tttgaaaaaa ataaaaagct
    30961 ttatcgaaga tcaaggtttg ttagatgatg aattttactc gatcgtaaat gatccgatgg
    31021 gtgcaattat ggaagtggac ttttactatc agataccaaa aagctataaa aaagtctata
    31081 acattatgaa aacgacagcg ccagatttag ataatttagt aaaaagtgct atggatggta
    31141 ttttcaacat ctcagctata cgagatagcc atatcacagg gttaattgct tttaaataca
    31201 atgtggcaaa cgaaggaaaa acagttgtga ggatcaagcg atattcagaa tttgagtggg
    31261 atacttctga aggattgaac ggagatattt gggaagccac atttgatttc aaaccagtag
    31321 caacgccaag accaaagtct aaatttagag gaaatgggat tatcacttac tatccaaaag
    31381 agtataacga ctatttggaa aatatcaaga atacgcttaa agagaaagat ttggtaaatg
    31441 atcaactgaa aaaggtaatg aatgctccta tgggggttat agctcagata gattattttt
    31501 accaagtgag aaaagataag aaaaagcttg attcactgat gcgtacttca cagccggata
    31561 ttgataactt agtcaaagga acattggacg gaatttttaa caaggaaatt ggcatcaaag
    31621 atagcagggt ggtaggttta atagctttta aatacaatac ttttgaaaag tcgaaaacaa
    31681 acgtgcgact acaggagatg ggctgatgaa taataacgaa aaaattcttc atgtacttga
    31741 tagctttgaa acaattcaag aggaactaaa gaaatatcga gatgttttgg aacaaagata
    31801 tgattttgtc aatcagcaaa agagtaatca catggatttc attctcaata tgaatgactt
    31861 gaagaagaaa ttagttgaac gaaaagaaca agaaaagttg atcaaagctt actttgaact
    31921 cggtgaaaaa gaagttaaaa aggcaatgga actgaatgaa gatcgcaggg ttttagatca
    31981 gctgttagaa caattattgg tgatgtttca aaaaggacga atagatgagg atttaattga
    32041 agaagggttg agaaagtatc ctgcaaactc aggtatcgga atagtgctga aagcgattga
    32101 tgaagaagaa attgaagatt tcataccggc agaggatttt gaatcggcaa tggaatatat
    32161 aaaatattac agccaaggga tcactgcttt tagagagttt gatcctgaag atgttattca
    32221 tgacttgaac aacctaaaag aatggtgtga aggttatgaa gttgatgatt ccggtttgga
    32281 ctacttgatc agtattatgg aaatcgaaga agagatgccg gataagcctg atccaacaga
    32341 tattttagaa ttaatccatg atgctagaaa tccaattgca tacatttcta gaggatatac
    32401 tgtattggaa tactataagc cttatatatc agcgatgaac catttaagac gtgtattaag
    32461 ggaaaaacgt gaataccgct cagtgttaaa tgcatcgaat agattagaaa aagctgtttc
    32521 agagctagat gcttattatc gtgaacatta cctgcaagca ggtggtatgc caagaaatac
    32581 gaaagcaaat atcagtaggt atataaaaga agctgagtag gcggagttag cccataaaat
    32641 ggcaaaaggt aacctgaaag aggcgttttg aatgaaaagg gatgtttttg aattgtacgt
    32701 attagaacgt ctagaagacg gcatgatggc acaagagata attgatgaaa ttgatgatat
    32761 gatcagcaga tttggtcaat tggaattgaa tgatggaaac aaaaattcgg tagtgctaca
    32821 acaattttgg ttaaataatt tttcgtataa ggattttatc aaagaaaagg caaatagatt
    32881 gtactgacta aattcacgag gatcagtgat gagagcttat tgctaagagc agttaggctc
    32941 ttttttgttt gtgttaaatt attttatttt acaatacaca tttatacaca aaaaatgttg
    33001 acggatagta cacaaatgtg gtaggatata tttgtaagca agttagatta acaagttaaa
    33061 ggaaggaaga gcagttatga aaaaagaaga actaatagat atgtttcaaa ttgttgaacg
    33121 agcaaataat atgggaatta tgttttttga tcgtatttct ttaaagatgg atttaagcgt
    33181 tgcccaccaa gaatttaatc tacgattaaa agctttattg atttctgatg atgttaattt
    33241 cgctcatgat gttgtaggta tacagaacca tatagataga gaaaacaaac gtatgggtga
    33301 tggattctta ccaagatatt caagtttatg atttggcgaa agattcaaga gtatgtgtca
    33361 ttattgatag gtactcttga attggaaagg aggaatgaat ttaagacaac aacgattatg
    33421 atcttaaaac aatcgtttat gtaattggca atcttacgaa taattttcat gcaataatga
    33481 caataaaaaa tgaaaagggg taaaatcaaa tgaaaaaatt tttagtagga attctattca
    33541 caatggggct agtgctatta tcaccttcag tttcagcaga aagctctatt tccatgtatc
    33601 gtatgtataa tcccaatagc ggagagcatc tatacactag aagcgttgga gaaagagaca
    33661 atctgaaacg ttatggatgg cattacgaag gtgtcgcgtg gcaagctcca acaagtggtt
    33721 ccccagttta tcgcttgtac aacagatata acggtgaaca tttttacacc gttgatgccg
    33781 gagaaagaga taagatttcg cacacaggat ggacgtacga aggtgttgcg ttctattcct
    33841 acaacggagc aaatagagtt cctgtgacac gcttgtacaa caaatacgtg aattggcacc
    33901 attacacgtt agatcaaaat gaaaagaacg taattagtaa acaaggttgg aagattgaag
    33961 gtacgggttg gtatgcaatg ccaaacagcg caccaaatcc tacacctgca cctgctccaa
    34021 gtaatgaaaa agtgttaaat gttcctgtca tttggcaagg taatacgatg ttgtgtgaag
    34081 gtgcttccct gttagaggga ttgcactaca aaggagtagc gacaaatcaa aacttaacca
    34141 gttttgtaaa ctatatgcca agagctaatg acaataatcc atatcatggc tattctggcg
    34201 aatggcgcta caacgtaaat ggtacgtatc aaggcatgat gcctgatcca gtagttaaat
    34261 gggcaaaaaa tgttggtggt aatgccgtta atatcactgg ttcaggaacg aatgggatca
    34321 agaatgaaat tcgcaatggt aatccggttg taacttggat tacttataac tatgcttcac
    34381 ctcaattcaa acaaatgcct tggggacgtg cagtctggaa tggacatgtg gttctcgtgg
    34441 atggcttcaa aaatggtgca taccatgttg ttgaccctgt atttggcgca aaatggatca
    34501 atgcaagcac gtatgagaga gcatttaatg tgactggaat ggcggttgct gtacgttaat
    34561 tgatagaatt aataaataaa tgaaataaga gcttaattac tgaaatggta aatgggctct
    34621 tattttttag aaaaaaactg ttttttgtaa tacgaattta taacaaaaaa cgttgaatgt
    34681 agtacacaaa agtggtatat taaaaccgta gagattatgc gaagaggtga ttttgatgaa
    34741 ccaaagaaga agaaaaaggc tagaagaaat aagcgagcga ctatccgagt taaaggatga
    34801 gttagaagta attcaagaag aagaggaaga gtacaaagaa aatatacctg aaaatctaca
    34861 gggatcagaa agatatgaaa aagcagaaga atccgttgat caacttgaag aagctgttga
    34921 tggtttatcc gacatattag aattgattga agatatagct agctagagat gattaatgaa
    34981 gatttcagga gtgagcaaaa aatgattgat atttcactga tagagaagct acttttttca
    35041 aataagtaca cagccaaaga gttggctaca agatggcaaa tatccgaatc agctattaaa
    35101 gcctatcgtc aaaataaggg aagcgtagga tggcgtgatt ggaaaggaat cagcattgga
    35161 aaagcagaag acataatgaa acgtgaagga tttcaagctg acaatgattc taaaaaagtt
    35221 gaatagttta atagtcgcca agaaaagtac caggacgagg ggaaaggtag attacaaagg
    35281 aaaacacttt taaataaact tcgcaaaagc atcaggttat gagtggctag ggctatacga
    35341 atgtgatgaa aacaaagggc tttaatgtca aagaaaacgc aatagggggg gaacaaaatt
    35401 tttaaaaaag atatttatgt ttggtttaat ggaaaaaaat atatgactac taacaaaagg
    35461 tggtcagagc tagtacaaaa tacagttaaa aaagtcatgc cagatggata tcatttcaac
    35521 tatatacaat gctcacaaac aactgaaagt atttattttt caatattaaa tgagaataga
    35581 ctctattatt tcagggtaag ttcacaccat aggaaaaaga gagaagataa tgttacgaca
    35641 tttttatcgg gaaaatacaa tggcttcaaa gagttaagtg aagccattgg tgagtatcta
    35701 aaaagtaata gatttgtcag aatttctgac aaacatatat tgatcttgtt actttatttg
    35761 aataatagct tcaaattgtt ttggagagac gacactttct actatattga gaacggcatg
    35821 gatatttatt ctggtatcaa cggcatatta aaacattata ttaaggcgtt acttcgatat
    35881 ggggttcttt atcaagaaga tttaagtaac caaattaaga ttagtaattc tggaaagtca
    35941 ttactggcaa aatataaaaa attgctttct cctatctaca aaggaataga tatggaagct
    36001 gtaaattctg aaactttatt taatttagtt gttgatgaaa agtttgcgaa tgaatttttt
    36061 aaaagtaaaa aaattgaaag actaaataac ctgtttcctg aaaatgcaat aaaagcttat
    36121 gtagataata ataaatcacg attatacaac tggtttattc ccaaacggtt gcgaggaaaa
    36181 atcaaaattg gcgatcaagt gaaagtaatt aatctaaatc atactaagat cgttaccgta
    36241 acggagttgt atatagctga aaaagaagat attacaaaaa tgaaaccagt tattaaaata
    36301 ctagataaca aagagtgagt ggaatatatg gtagcaaaaa agaatactct aaaagaagct
    36361 tctgaaaaat atcaagatat gaaaagacga ggattaatac caaaggacaa aaaaggtata
    36421 tggagagaat ttgttaagga agtcagtagt gatcgaagtg gcggtgactt tgttggacga
    36481 tatacagcaa aaggttatag caggcgctta aggatcactg ttgaatatgg aacgaatgaa
    36541 tcagctaaag agctgaagca aaggtactta gatacacgaa gagaagcttc aaaaaaatat
    36601 gatgatttca agagcagagg tctaattcct aagaagaaaa aggggatttg gcgtgagttt
    36661 ttcaaagaag aagatagcaa tcggaataag ggagacttca ttggacgata cacagcaaaa
    36721 ggctacacta agaatttagg gatcaaggtt gaatacggaa ctggtgaaag ttcatgggaa
    36781 ttgagaaatc gctatttaaa tacattgtta gagaaatata aagcagaatt attggagttg
    36841 ttcgatgtta atgattttat cgagatggct gaaaagtatg gtcatgaaga aggttttatg
    36901 atcaatgaca ttatggttat tgataatttt acggatttat tagcacttgc gaaaaaagca
    36961 agggatttaa gagaaacgca gatgtatcta ttcagaaata aaaacggaag aaaccggaga
    37021 actgaatcga gtgagattga agattactat gatgccttta cacacgatct gggagccttt
    37081 gtagacgaga taagtggtgt aatgaacaaa tatagggtct agaataaaaa agccggagat
    37141 gagcagataa atgggaaaca atagcatata cacacctgaa atgcagaata aaattaaaag
    37201 acttgtcgga ttagggtgga tgacaagagg aaaattagat tcttttagta cgatcaaata
    37261 tcttttgatg gacatttacc gtcagaacaa gcaaacagga atacattttt tgggctatga
    37321 taagccggaa gatgcacctt tctttgttcc aagttcagcc tatagagcca gtacctccgg
    37381 tagcatgtat aacttggatt tgtttgagga aggagcaaag atgatcgaat atgatttcaa
    37441 cgaagcctat tcgaggatca tgagaaatta tcctttgccg tcaaacactt atttgaaagc
    37501 aaaatataat acagatcaag ctattttgag agcgataaat agaccaaaag taagaccgta
    37561 tgaaaattta aaaacgtata tgttcttttt ggttaatttt gaaggaacag ccaaagaagg
    37621 aacatatgct aatccaaaat cacagtcgat gtttgcggat tatggcgaaa atcccaaaac
    37681 agctaatgag cctatttggt tatcggagat tgagctaaca cttatccttg attattatga
    37741 tattaaagag atggaagtcc tagatagcca cacatttttg acgaaaaaag gattactcaa
    37801 agaatatttt gaaagaatcg agccattaaa aactgatcct gatacgttga agctttataa
    37861 aaatcttaga acgaaagtat ttggtgctat cggacaaaaa tcattaagag aaggagaaac
    37921 aagcaccttc gataaataca gtatgtataa tcgagcgtat tcctccatgg tagcaggcgt
    37981 atttagagat cgtatggtta gatatgaaca gaaatacgtt catagcgcat atgggctatt
    38041 aaaaattcgt actgatggat tgtatttcag atccgaagta ccagagtttg aagagctgta
    38101 taaacttgga gtagttaaga aaaaagttca tacaatatcc aaagaagaag tcgaaaaagc
    38161 tttagaattt aaaaacaaag gatttgaaaa taagggctcc tttgggaaat ctaaagatga
    38221 agttaagggt gttgtgatag acgatgattt cgagtttgat tttgactaaa tactctttgg
    38281 aaaagatggt aggaggtaaa tatgaagaag aaaattgtgg aaggaaatgt aggtgttatt
    38341 attctaaaag attcaactga ctatgctaaa tcaatggcac taaaagacga aaaagttgca
    38401 cgcatggata aagatttagt tgaatttctg atggatgata cagaaagatt aaaaggggat
    38461 cagtttttga gtttaatgaa agacaaaggc ttaaacacat atggtttatt tgattataag
    38521 aaattagcta tagagtgggt aaaagaagga gaaatatttt ttattgaaga atgggaaggt
    38581 actgagaact tagttcttca tcagtatctt ttgaaagctt aatctaagta aaacagttct
    38641 gactagttat gcttgtcaga atttcaaagg aagttttcca taaccatcat cattcaaaaa
    38701 taaaggattt gaaaataagg gttcctttgg gaaatctaaa gatgaagtta agggtgttgt
    38761 gatagacgat gatttcaagt ttgattttga ctagattttt ttgcaatgtt taagagtaaa
    38821 caaggtaaga actaagatca tgaagattga gagtaaagaa gatagaggac gaatgtatga
    38881 gaacacacta tatttattta gaagataaaa ttgtagatga aattccggca aaaagtcgag
    38941 aacaagctag aaaattattt attgaaaaat acaaagagat caatggagat agtgaagttc
    39001 caaaagtggt cgtaacagtt agaaaaaggc aaacaaaaaa gagaagtacg tttcatgtca
    39061 gccctgatat atataatctt atagagcgac atagaagtga agataatatt tctatctctc
    39121 aatatattgc tacagttatt gatgaattga tttcaggaaa gtatgactat gcttttgatt
    39181 ttgagggtga aaaggattac aaaagtgttg ctgtctttca atctgatttt gagaagctaa
    39241 aaaactatgc tggcaggaga aatgttaatt ttgcaagact actagaagag ttctactccg
    39301 aagagttggg agtaggaaat gaatacaaga gagaaactta tgcgaaattg tctcataagt
    39361 tatcccaagc gcttaaagaa gtgacagaag ttaaagcgga actagatgct aaacttgaag
    39421 aagtgaaaaa atatcaaaca gagaggaaga acaacatgaa gaatcaagtg gaatttgacg
    39481 aacagaaaga atttgaaaaa gcaagaaaac gctataacaa aattatgaat gaacttagct
    39541 atgaacactt aacagttcat gaataattga gtgagggtac agaaaaatat acgatcgcag
    39601 atatggttaa tgaagtggaa actcttttag cttctttctt tgaaaatggt cacgtaaacg
    39661 atgaatggcg aaaagaagaa cctaaaaggg ttaacgctta tattgctcga ttaaaaaggt
    39721 ttattgataa atataaggag aatagtgaca aattttctaa agataaataa ggagagagtg
    39781 tgattacatt tgccagaaat cgaaggaata ttttcgccaa aaataggtaa aaaacagtta
    39841 gatttcagca gttttccgag cgtaaataga gattataatc taggtgatga ggtacagata
    39901 ctaaatattg atttcaaaga actagacttc gctgttgctg tttccaacaa acccaaggca
    39961 ttggaacgag tgaaaaaaat ataccaagag aatgatcaaa atatcaaaaa tatgatcaaa
    40021 aagtatagac gagataattc aaaagttgaa gacgttttat tcaacggtac ggcaaaacat
    40081 gatttgaatg tttatatggc attaggagtg gctttgtact gtaattcaat taatcagaca
    40141 gatattttgg ttaatatcgt gaggaatagc tatcaaaaaa tattaaaaat aagtagcgaa
    40201 acaaaccctt attatgcaat gaaatatctt ggggataatt tattaaatga taaaaaattg
    40261 atgcacaaca ctgaagagct gttatctaat ttggctgcga ttaactttct attcaaaaca
    40321 ggttctgaag attattttat agataacgta ctaaaaggtg cttacggaac agcattttat
    40381 ccgctttaca atatgaaaca gcataaagcc gaacaaaagg ataacaaact tgaaattaaa
    40441 aagatgaaag aactattagg tataggattt gtaaaaccca attcaaaagt cactattgct
    40501 tcgttagcaa ctactaacaa tgatgggaaa atagtaaatg ggtttgacga ttcagatata
    40561 gatatattgt caaaatcata tttttctttg tatggagatt ttgcagattt gatgggtatt
    40621 gatagttact tagtcaataa ttttgagatc aagggtagcg agctgaatga tattgtgtat
    40681 ttcgttttaa tctctctata tgcaattgat cagaataccg agtaccgaca aattgactat
    40741 ttgctagttt tttatagttt gttatatcag ttcgttttaa ctcggttgtt taaaaatgct
    40801 aaggaagaat tgatcctgaa ttctgattat gaaatagcaa aacaaattgc aagtattaga
    40861 aaagaaaaca aatctgaagt aatcaaatta agaaaagaat taagtattgc gagtaaagaa
    40921 aacggtcggt tagaatcttt agtcaaatcg gcaaaaaaag aagaggaact tttgaagcaa
    40981 gagattaaag aattaaaagg aatcagaaaa gaacttgaac agctgaggtt tgaaaataaa
    41041 gtattaaagc aattgcagga gcaagaacat agacaatcat taaatggtaa aactgaagag
    41101 ccttcactgt ctgaaatgat agcttatcta aaacataaaa acattctttt agtgggagga
    41161 catgtaaatt ttcaaaataa attaactgaa ctattaccaa atattaaaat gtttgatgta
    41221 agcgaaaata atggaaagat acttaaaaat ttgaatacgt gtgatgcgat ttttctatat
    41281 acagattact tgaatcatgg tctatattat cgtgttatga gtgaaatttc taataaagat
    41341 aagatatttt atttggataa tcatgtgaat atgaacttaa caattaaacg tatttacgat
    41401 cttttatcac ttatataaag agagaagtga taaataggac acaaaatttg gaaagtaggt
    41461 aagtcactat gagagaacta actttatctt ctaaggaatt agaaaagaaa actgctttat
    41521 taaacgaaat atttagtgct gattgtataa tccaaagttt aaaagaaagt tcattttcaa
    41581 aactaacaga tcaggaaaaa atttcttata tgctaagttt agataatcta ggaactaaat
    41641 atgatgaatc agcaagtagc gataagcttt tgattgaatt agtatcaagt cttagtagtt
    41701 ttggaaaaat gaaaagattt aatgtgatat tagaaatttt tgcttggtta atcccttcat
    41761 ttatttggtt tttttatatt ttcatagttg aatctgagtt aatagccaag gtctctcttg
    41821 gactgttaat tccgatataa ataggttcag caatttactt taataacttg tatacacgta
    41881 ttcaaataaa aaagcagtta ttacatgaag gattaagtgg taatatgtta aaaagaattg
    41941 catgggataa agataataaa acagatattg agcttaaaga atataaatac aattatttct
    42001 cgagatgtat agatagaaag ttactgttta aaaaagaagg attagaattt agttttgatg
    42061 aagatgaatt tgaaaaatta gtgatggact ggcgtaagaa tttactggat acggtacaat
    42121 tctaaaagca attgaggtcg aaattccgat acttgaatca tgatctatat tatcgtgtta
    42181 tgagtgaaat ttctaataaa gataagatat ttcatttgga cagtcatgtg aatatgagct
    42241 taacaattaa acgtatttat gatcttttat atgtttataa acattaatga ggtgctaaaa
    42301 ttgacaacaa taactatgac aaaaaaaata gaagtatatg ttgatggatc acaagaagaa
    42361 agggattcct tttttgattt tttttggaaa aatagtagag aatatgtaaa agcgttgaat
    42421 ctggtatata aacagctaat gtttgaagag ttgataaaag atgcaattaa agaaatggat
    42481 caaggttatg ctgagagaga agaaagtatt caaaatcgga ttgaaaagtt agcatatact
    42541 gatccaatag atcaaaaaaa acttgataaa gcaaaagctg aattatctaa attgagaaat
    42601 gaaaaaaata aagaagcgag agaaatatta acgcaagcga tagggttgaa gagtcaaacg
    42661 agaacacgag atgtagcaaa aaaattagac tttgactttg gagattttgt tgattccgca
    42721 aatatgaaag ctagtaaaga ttttggcaat gattttatcg gaattgtgac cggacaaaga
    42781 acgcctagaa tatataaaaa tagaaacaaa tatggattac taccttttag aggtcgagat
    42841 attaaaatcc ataaagatga taagttttat atttatttac ctaaaggctt taggtttaaa
    42901 gtgaatttag gtagcaagcc aagaaaagca agagatgttg cttcagtttt acaacacatt
    42961 atggatggcg attacaaatt aaatcaaagt aatcttattt ttgatggaag aaaattattt
    43021 tttaatctaa caatttcttt tgaaaaaagc tataatgaaa tggaattcaa gaaaggtaat
    43081 gaattgatcg taaactttgc agatttgtgt agcggtgaat gtttaattaa tgataaatct
    43141 gtaatgtctt ttggtgatag ccaatatata agaaacttca aaagtaaaat tttagcaatg
    43201 aaatcaaaag aacaaagccg aggagtcttt tctaagggcg gtcatggtcg aaaaagaaaa
    43261 ttagatcaag atcgatggga agcaataaag aaaagagaaa gtaattttgt taaaacttat
    43321 aataatcaat gttctgcaaa aatcgttaaa actgctattc gcaataaagc tcaaattatt
    43381 cgtatcattg aaccagataa ggcttatggc gaatgggctt actatcaatt gaaagaacaa
    43441 ctagtaaaca aaggaaaaag atatgggata gaagtcagaa gttagtaaat taaacaatcg
    43501 ttgatttggc aacgaaatag tgagggaaaa tccactcact gaagggtaaa ctccgtcaag
    43561 ttgtgtgacc agacggaagg acgaatgttg ttgaggtttt agaaccatat aaaacagcat
    43621 gtttctcaaa tgagtacttt aaattaattg atggcgttcc tgctttagaa ccatataaaa
    43681 caacatggat ttaaaacaag aagtaagtca gttctccttt tactttagta aggaaaaata
    43741 aagtattctc aataaaactt aaaataagca aacctttgtt ttaatagcta atcgaagtaa
    43801 aacccaaagc catatgaacc cctgaatcag cgaaagttta tgatgatttg gattactaat
    43861 agtttaggaa ttagatggta aatctaaatt aaacaatcgt tgatttggca acgaaatagt
    43921 gagggaaaat ccactcactg aagggtaaac tccgtcaagt tatgtgacca gacggaagga
    43981 cgaatgttgt tgaggtttta gaaccatata aaacagcata gttctcaaat tgtttaaaat
    44041 gattgtcaag ttaaaaaaat ctgggatcat ataaaatagt atagttctca aatatgatta
    44101 gaaaccctat taaagagcaa tattaagcca acttacttaa atcgtttaat taagaacaat
    44161 aatctctttt agtcagactt ttagtctgac ttttttgtat ttccaaaatt tattctttac
    44221 aaaaacgaac atacgtttgt ataattgctt gtgaatgggg gaataaaaat gtttgattac
    44281 agtagagaac cggtgaatga ctatttttta atcgacatga agtctttcta tgctagcgtg
    44341 gaatgtattg aacgaaattt agacccaatg actacaccgt taattgtcat gagtagatcg
    44401 gacaacactg gttcaggtct gactctagct tcttcaccta ctgcaaagaa aaaatatcat
    44461 attactaatg ttagtagagc tactgattta ccttatccat taccaaaaga acttcatatt
    44521 gttccaccac gaatgaactt atatataaaa aaaaatatgg aagttaatca gatttttaga
    44581 aagtatgtcg cagatgaaga tttattgatt tattcgattg atgaatcaat tttaaaagtg
    44641 acaaaatcct taaatttatt tactagttca ggaacaagaa gcgagagaag aagagaatta
    44701 gctaaaataa tcaaagatga gattcagaaa gaaacaggtc taatagcaac agtcggaata
    44761 ggagataacc cattattagc taaacttgca ctggacaatg aagcgaagag tagtaaagaa
    44821 tttatagctg agtggactta tgagactgta cctgaaaaaa tatggaaaat aaacgagatg
    44881 actgactttt ggggcattgg atcacgcatg aaaaaaagat tgaatcatat gggaattatg
    44941 agtatagaag atttagcaaa ttggaatccc tacacaatta aaagtcagtt aggtgtaatc
    45001 ggactccagt tatatttcca taccaatgga attgatcgta cggatattgc tattccacca
    45061 gaaccaacca aagaaaagtc ttatgggaat tcacaagttc taccaaaaga ttatacgagg
    45121 agagaagaag tagaactagt agtcaaggag atggcagagc aagtagccat tcgaattaga
    45181 caacacaatt gcaaaactgg ttgtgtacgc ttagcaattg gtacgtcaat tttggaagaa
    45241 aaatcaggtt tctcgcacca gatgaaaata ccaattacag ataatacgaa agaattacaa
    45301 aattattgtc tttttttatt caataagttt tatgaggggc aggaagtacg acatatagga
    45361 gtaacttata gcagattagt atacacagat tccctacaat tagatttatt tagtgatcca
    45421 agaaaaaaga ttgctgaaga aaatttggat aggattattg ataagattag acaaaaatat
    45481 ggatttacag ctattataca tgcttcatct atgttagaag gtgcaagaag tattacgaga
    45541 agcactttaa taggaggaca cgcaggagga ttaggaggtt tgcataatga ttgaatataa
    45601 cgatagagga cgtttaaaat ggtcgggatt ttatttgtct gatcatactg aaagaatcaa
    45661 tgcagacaat gtacaacgtg ctaatcataa tttggcaaaa gaacaaatga cgactgaaga
    45721 gattgcgaaa atactgagaa ctgctgtcat aaaaaataga cccgtctgca ttcaaaaaga
    45781 ggaacgaaac gctgaaggtt actatccaga tgatgtagta ggaaaaatta ttggatatga
    45841 cgagcttggt gtatttgtgg aagaagaaaa agttcactat gatgaaatta ggaatgtttc
    45901 tttctcggaa ttattaaaat ggagtcagat atgaacatta ttaaaaaata cgaattcggt
    45961 tatattacgt atgaacagct aatagaggaa ttatggggat atggtcaaca attaattaat
    46021 gaagtgggga ttgattgctt ttgtttctat attgaatccg gagcaggata ccataagaac
    46081 agatactata tatttccata tccaccaaaa tagtctctta gatattttta aattttctcc
    46141 aaatactttc aattattgtg aaatatttcc ctttaattaa tcaaattttt tataaaagta
    46201 atatataaaa taaattgctt gaagtattat atttagatat cataatttat ggaagaaaaa
    46261 ttaattaaaa aggatgagat tataatgggg ttactggttc cgagagctaa tacttatact
    46321 atacctttaa cgaaacgcca attaattgct gaaagatatc aaaggattac tagagccatc
    46381 aatagagagt tttggaattc tgaaagtgat actgctcaca gtttatacgt aggttcttat
    46441 gggagaggaa cggcaattag tactagtgat atagatataa tagttgaatt accgatggca
    46501 gaatttgaca gattcaaaaa ttatttatca aatggcccgt ctaagttatt acaagttata
    46561 aaaaacgcat ttcaggaaat actaccaaat agtgatatta gagctgatgg acaagttgtt
    46621 aaaataaatt tccatgatgg aatcaaattt gaaatagttc cagcttttaa tgaaaaagat
    46681 tattggggtg agtcaaaagg gtttatttat ccagattcaa acatgggagg gaactggaaa
    46741 gctacaaatc ccaaaaaaga gcaagaagcc atgaaattaa agaatacaaa aagtaataat
    46801 ttattatatg ctacgtgtaa acattttcga catgtacgag atacagaatt tacgagttat
    46861 catctttcag gaatagtaat tgacagtttc gtatatgagg ctatgggaaa ttggaaattc
    46921 gttgaaaata acagtggggg tcaaaacatt agttctgtat cttatgagac agctttatta
    46981 gaatactata actcacataa agttatgggc ggtttaaatt tatactctcc tggaagcaat
    47041 caatttgtta attctgatag tagtatcata tgtttagaaa aagtattaaa aaaaatagct
    47101 ttataaagtt ttatggagga acaacatggg agacgaaaaa aagcgcttgg aagttcaatt
    47161 acgtgaagca tatggacgag taacgtatac ttacaccact catttaaagc aagccgataa
    47221 tattatttct gacaataaaa ttttaaggtg tcttcaaatt ggtttgtcag cccttactac
    47281 tggaggggta cttagtacca ttattactga taatagtgag ttaacctttg ttgctggatt
    47341 atgttcaaca atttctcttg gattaaactt atactttaag aattttgatc ttgctgaaga
    47401 agctaaaaat catcaaattg ttgccgataa attatggttg atcagagaag aatacgtaag
    47461 cttactaaca gatttaaatc gtttaagtgt tgaagatatt gtgaaaaaaa gagatcaatt
    47521 aatgaacgaa actcatgaag catataaaaa tgcccctaaa acaaatagta aaagctatga
    47581 atcagctcag aaagcattaa aatctgaaga agagcaattt tttacagaag aggaattgga
    47641 taagatgtta ccagagcatc ttagaaaaaa gagttctaaa tattgaactc tttttttatg
    47701 cttaaaattc tcttgtaatt tttctattca tctatattta agaagaaata tgatgataga
    47761 aacatctcct aaagccaccg caagccgttc taagcatagc ttagcccgac attgctagat
    47821 atgctcatct caccatgaac gtttcctaaa gccaccgcaa gccgtcctag ccattgccta
    47881 gtccgacatc gctagattag tgcatctcgc cataaaagtt ttctaaagcc accgcaagcc
    47941 gtcctagcca ttgcctagtc cgacatcgct agattagtgc atctcgccat aaaagttttc
    48001 taaagccacc gcaagccgtt ctaagcatag cttagcccga cattgctaga tatgctcatc
    48061 tcaccatgaa cgtttcctaa agccaccgca aaccgtccta gccatcgcct agtccgattt
    48121 tgcttgatcg gttccatttc tgtttattta gtgggtcaac accgtaatct taaatagcca
    48181 tcgcctattt aagattacta ggtctgcttt gaaggtaaaa agtctttcat tcttcaagac
    48241 ttttaggctt tcaagctacg cctgaaagca ttgaaattca tcgctcttta tttggttttg
    48301 ccatttataa ttccttacgc ccattatctt tttcgcctgt cataccttgt cagaagtgtt
    48361 tagagcttat ctcatctttg gattaataca agtggcgtaa atttttttct aaacgcaagc
    48421 gttacgaaaa taatttactt aaacacttgt attaatccgg cagataagaa cgcattctaa
    48481 tcactcccga caaggcaaga caggcgaaaa agataaataa atgaacgaaa ggaagaaaca
    48541 taaaatgcaa aaccaaatag cgatgaagaa aaaaccacct ccctctaaaa caatccaaac
    48601 aaaaaagaat tttgaaaaac caaaaatcaa aaacagaaag aagcgttcaa catgagagat
    48661 agaattttag aagttaatca agaaatggta aacaagttaa caaatatcag tgggaactat
    48721 gaaaagtacg atggtacttt acttgataac tatatttttc acgatacaca aaatatcaga
    48781 attggcagaa gtaaaccgag agcgttcatt ctcatcaaag agaaatattt gaatgaatgg
    48841 aatagcacct atgaaatggt tatgactgat aactttgaaa aggtattgga tttcagaaat
    48901 gctttgttgg gttctgatat gggaaatagc agtcttgaat ctattgaagt tgaaaacaag
    48961 accgagaatg aaggtgaagg attgattaag aatgtcttga aaatcgaaca aaaatatatc
    49021 agtgaagata gaagttttta tagagtcaca agctcggttg gtctagcaaa ctttgctact
    49081 aacttaattg gaaacaatgc tagtgaatct ttgctagtga tgtgtctgaa tacaaagaat
    49141 gaggtcattg cttatagcga agttttcaaa ggtggaatta atcaatcagt agcgatacca
    49201 agagagattt ttcaactagc tttgctaaac aattcagcaa aaatcgcagt atcacataat
    49261 catccgagcg gatatgaatt tccaagtgaa aatgacaaaa gttttactac gaatttgaaa
    49321 aacgcaggaa aaacaattgg tattgaattg ttagaccata tcatcgtaac aagtaaaaac
    49381 acaagctatt actcatttca agaaaatggt tctttataaa aattagagaa aagaggaaaa
    49441 caagatgggc gaaagaacac aagcgttaat tacagtcaaa tatggtaaca gcaaaacgaa
    49501 agcaagcgtg tcgattcatt atcagtgggg gtatggtcga tatatgctga tggacgtatt
    49561 gaatcaagga atttatttaa tcaataaagc atacgactta cgagataaat caagagaaga
    49621 attagcaaaa ggaatctttg atagaagtac aggagttatc aattttgtta cctatgaatc
    49681 tggagtgagt gcttatgatg aaacagggtt tggtgggcgc tatgaacctt atcaagaaac
    49741 gattgaagat gtgatgaagt tttcagataa caatgatggc tatgctcatt tagagatggt
    49801 gttcgatgaa aatggattta gtctagatga taaaaccaga ttgcgattgt ttgattttga
    49861 gggtcaacag ataggactaa acaagttttg tgaaagcgga aaagagtttg ctacgaaaga
    49921 ttttattaag ggatacagat tattgctaga aaattatgga ataaacctag aagaagagag
    49981 cgtgaaataa gtgtttgaaa aaagaaaaga ccagttccct aatttagaag cggaaagtca
    50041 aaaagtgatt gatggtgaaa tgattgaatt attccaaaaa agttatggaa ccatagaaac
    50101 taccgcaagt tgcaaatact actttcaagg aaagagaaac acgtttaaag gctttgccga
    50161 ttctgatgaa gaattggcaa agaaaatcat tgattggctt gtcagcagtg aacacgtagc
    50221 aagggaagat accgttagaa caacgattaa tggggaagtc ctaacaggta ctagatgtgt
    50281 ttgttgtaat catgaatttg tagaagatga aggttgctac cgaatcaatg aatatggtga
    50341 ttttatttgc cagagttgcc acgagataga atttccaacc gaaagaagtt ggtttgaata
    50401 catgctacaa gattatgaga tggaaaaaga aaatggtgaa gtagtttttt gtaccaaaga
    50461 ggaattgagt aagagaagcg atgatgaaat tgaagattgg tgtgtgtggt tagtaggggc
    50521 agatgattgc gttgcatatt acacaacagc agaataggag tgtgaatcag catggaagga
    50581 atggattttc tagatcatga agatttggtt gattttggtt atacatggaa aggaatggta
    50641 ggtattagca gaagtcttgc taatgccttt tacgaaagaa attatgcagt atatgttctt
    50701 tatgatgacg atacagaaag ccttgttgac gaggaatata aattggattt agagaatgtt
    50761 ttatatggaa tagaaaagga agatttagca aaatatattt tttcatggtt gggtcaataa
    50821 gtgaaaggaa gatagaaaca tgacaaaatt taaaagtaag ggtatgcaat ggtgttctta
    50881 ttattatgtt ggaaatgatg aagatttatt gagaaaaacc caacgaaaag gttatccaga
    50941 taagatattg aaacaaatag gttattacat gccagaagag aggatagaaa aagaattttg
    51001 tgaggttctt tttgatagtg aacagctatt agttttgtta acccaaaata aattgatttg
    51061 ccaatttgaa aataattaag atgaggtggt gaaccatgaa tgaagataag atggtattaa
    51121 gtgaatatgc tagattgaga actattaatt ctttagcatc tcatttaagt tgttctttcc
    51181 taacaaaggt gctaaaatta atttacaaat gtgaagattt tgtacaagag aagcacaaag
    51241 acaagcctac tgcgaatagg cttgtctttt tttcattcat tacgattccg tatgtgtggg
    51301 ttagcgacaa tttgttcaat taccgtatga tatagcatct taatttgatt agattacttg
    51361 caatgtagtt tattaagagt ataatataat cataaatgtg gacaatttga taaataatga
    51421 gtgttttata ctcaaaagga gtggatgaaa tgaaggtcaa aaatccaact gaaaaaagca
    51481 gaatccaagt cggaatagac aagaatttaa aagagaacgc agaaatgata ttggaagagc
    51541 taggtttaaa tcctacaaca gcaataacaa ttctttacaa acaagtagtc gctagaggtg
    51601 agtttccagt agagataaag ctaagtgaag aggagaagca aggaatcaga ttgcaacagc
    51661 taactaagga catgccagta gatgttctag atacagatga aaagttagaa gagtggttcg
    51721 atgaagccta atgagatagt aacggtatat gttgcattta cagataaaaa tggtggtaaa
    51781 agaagaccta ttttggtggt tagtgataaa gaagatagag tagaattctt tggaatcaca
    51841 agtcaatatg agaaaaaatc agaccaaata aagagggtgt attttcctat tgcagaatgg
    51901 gaaaaagcag gacttaaaaa gcaatcatgg attgacgtag ggtctttaaa ggctattccc
    51961 aaaagccgag agaacatatc attcaaaaag gttggtatgt tatcagctag tgatacgaaa
    52021 aagctaaata ggtttatcga gaaattacaa agaaaagtct aacaaggctt ttcttttttg
    52081 tttatatgta tattaagata tacgtttata taaacgtatt tatgtatatg aaaatatacg
    52141 taaatatata cgtggttata aacattaata aaacgttaag aattgttaaa taatgatatt
    52201 tagtaatata cgaattataa tatatatttt atataaaatg tatgtaaata aataaaatgt
    52261 ctgacggata ttgaatagca ataaataaca ataattcaga cggatacggt gagtgaagta
    52321 gcttgctacg aacgaacagg cagaatgaaa cggcagtttc attagagcaa gtcgcttgcg
    52381 acgtagcgtt accgctgatg taactggcaa gttacataga gagagtttgc ttgcaaacga
    52441 acgttaccta tttgaataga aataaaaaat aacagattag tgaattttga ataggagcca
    52501 caactcaacc aaccgcttgc ggtgggtgag tcccacggag gaaaagacga acgaacggtc
    52561 gcgt
//
LOCUS       DAPBBV010000019        52446 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.019, whole genome shotgun sequence.
ACCESSION   DAPBBV010000019 DAPBBV010000000
VERSION     DAPBBV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.019"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            1..792
                     /locus_tag="RD486_001350"
                     /pseudo
     CDS             1..792
                     /locus_tag="RD486_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
     gene            932..1858
                     /gene="cysK"
                     /locus_tag="RD486_001351"
     CDS             932..1858
                     /gene="cysK"
                     /locus_tag="RD486_001351"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDT7663088.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2094..2540
                     /locus_tag="RD486_001352"
     CDS             2094..2540
                     /locus_tag="RD486_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7663089.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2812..4164
                     /locus_tag="RD486_001353"
     CDS             2812..4164
                     /locus_tag="RD486_001353"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HDT7663090.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            4335..4622
                     /locus_tag="RD486_001354"
     CDS             4335..4622
                     /locus_tag="RD486_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663091.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            4848..5291
                     /locus_tag="RD486_001355"
     CDS             4848..5291
                     /locus_tag="RD486_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7663092.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5297..6481)
                     /locus_tag="RD486_001356"
     CDS             complement(5297..6481)
                     /locus_tag="RD486_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HDT7663093.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6749..7447
                     /locus_tag="RD486_001357"
     CDS             6749..7447
                     /locus_tag="RD486_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDT7663094.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7454..8131
                     /gene="nth"
                     /locus_tag="RD486_001358"
     CDS             7454..8131
                     /gene="nth"
                     /locus_tag="RD486_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDT7663095.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8257..8790)
                     /locus_tag="RD486_001359"
     CDS             complement(8257..8790)
                     /locus_tag="RD486_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663096.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9087..11468)
                     /locus_tag="RD486_001360"
     CDS             complement(9087..11468)
                     /locus_tag="RD486_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDT7663097.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11458..12105)
                     /gene="recU"
                     /locus_tag="RD486_001361"
     CDS             complement(11458..12105)
                     /gene="recU"
                     /locus_tag="RD486_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HDT7663098.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12169..12708
                     /locus_tag="RD486_001362"
     CDS             12169..12708
                     /locus_tag="RD486_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HDT7663099.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12798..13217
                     /gene="gpsB"
                     /locus_tag="RD486_001363"
     CDS             12798..13217
                     /gene="gpsB"
                     /locus_tag="RD486_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HDT7663100.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13239..13606
                     /gene="rnpB"
                     /locus_tag="RD486_001364"
     ncRNA           13239..13606
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="RD486_001364"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13815..14981
                     /locus_tag="RD486_001365"
     CDS             13815..14981
                     /locus_tag="RD486_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDT7663101.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15027..16523
                     /locus_tag="RD486_001366"
     CDS             15027..16523
                     /locus_tag="RD486_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HDT7663102.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16604..17287
                     /locus_tag="RD486_001367"
     CDS             16604..17287
                     /locus_tag="RD486_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7663103.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            17932..19122
                     /locus_tag="RD486_001368"
     CDS             17932..19122
                     /locus_tag="RD486_001368"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDT7663104.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19224..20177
                     /locus_tag="RD486_001369"
     CDS             19224..20177
                     /locus_tag="RD486_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDT7663105.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20246..21595
                     /locus_tag="RD486_001370"
     CDS             20246..21595
                     /locus_tag="RD486_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7663106.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21778..22101)
                     /locus_tag="RD486_001371"
     CDS             complement(21778..22101)
                     /locus_tag="RD486_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663107.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22230..23393
                     /locus_tag="RD486_001372"
     CDS             22230..23393
                     /locus_tag="RD486_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDT7663108.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23463..24812
                     /locus_tag="RD486_001373"
     CDS             23463..24812
                     /locus_tag="RD486_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7663109.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(24857..25287)
                     /locus_tag="RD486_001374"
                     /pseudo
     CDS             complement(24857..25287)
                     /locus_tag="RD486_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            25675..28317
                     /gene="alaS"
                     /locus_tag="RD486_001375"
     CDS             25675..28317
                     /gene="alaS"
                     /locus_tag="RD486_001375"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDT7663110.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28517..29113
                     /locus_tag="RD486_001376"
     CDS             28517..29113
                     /locus_tag="RD486_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7663111.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29235..30383
                     /locus_tag="RD486_001377"
     CDS             29235..30383
                     /locus_tag="RD486_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7663112.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30421..30834)
                     /locus_tag="RD486_001378"
     CDS             complement(30421..30834)
                     /locus_tag="RD486_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HDT7663113.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            30913..31344
                     /locus_tag="RD486_001379"
     CDS             30913..31344
                     /locus_tag="RD486_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HDT7663114.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31443..31676)
                     /locus_tag="RD486_001380"
     CDS             complement(31443..31676)
                     /locus_tag="RD486_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HDT7663115.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            31859..33529
                     /locus_tag="RD486_001381"
     CDS             31859..33529
                     /locus_tag="RD486_001381"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDT7663116.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33676..34062
                     /locus_tag="RD486_001382"
     CDS             33676..34062
                     /locus_tag="RD486_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663117.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34049..34747
                     /locus_tag="RD486_001383"
     CDS             34049..34747
                     /locus_tag="RD486_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7663118.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34752..35216
                     /locus_tag="RD486_001384"
     CDS             34752..35216
                     /locus_tag="RD486_001384"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDT7663119.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35213..36124
                     /locus_tag="RD486_001385"
     CDS             35213..36124
                     /locus_tag="RD486_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7663120.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36359..36898
                     /gene="pyrR"
                     /locus_tag="RD486_001386"
     CDS             36359..36898
                     /gene="pyrR"
                     /locus_tag="RD486_001386"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDT7663121.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            36912..38195
                     /locus_tag="RD486_001387"
     CDS             36912..38195
                     /locus_tag="RD486_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDT7663122.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38208..39134
                     /locus_tag="RD486_001388"
     CDS             38208..39134
                     /locus_tag="RD486_001388"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HDT7663123.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39153..40433
                     /locus_tag="RD486_001389"
     CDS             39153..40433
                     /locus_tag="RD486_001389"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDT7663124.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40438..41514
                     /gene="carA"
                     /locus_tag="RD486_001390"
     CDS             40438..41514
                     /gene="carA"
                     /locus_tag="RD486_001390"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDT7663125.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41519..44704
                     /gene="carB"
                     /locus_tag="RD486_001391"
     CDS             41519..44704
                     /gene="carB"
                     /locus_tag="RD486_001391"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDT7663126.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44758..45534
                     /locus_tag="RD486_001392"
     CDS             44758..45534
                     /locus_tag="RD486_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDT7663127.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45531..46463
                     /locus_tag="RD486_001393"
     CDS             45531..46463
                     /locus_tag="RD486_001393"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDT7663128.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46460..47176
                     /gene="pyrF"
                     /locus_tag="RD486_001394"
     CDS             46460..47176
                     /gene="pyrF"
                     /locus_tag="RD486_001394"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDT7663129.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47183..47812
                     /locus_tag="RD486_001395"
     CDS             47183..47812
                     /locus_tag="RD486_001395"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDT7663130.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47800..48114
                     /locus_tag="RD486_001396"
     CDS             47800..48114
                     /locus_tag="RD486_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663131.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48152..48793
                     /locus_tag="RD486_001397"
     CDS             48152..48793
                     /locus_tag="RD486_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7663132.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            48836..49528
                     /locus_tag="RD486_001398"
     CDS             48836..49528
                     /locus_tag="RD486_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HDT7663133.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49525..50427
                     /locus_tag="RD486_001399"
     CDS             49525..50427
                     /locus_tag="RD486_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7663134.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50585..52291)
                     /gene="efbA"
                     /locus_tag="RD486_001400"
     CDS             complement(50585..52291)
                     /gene="efbA"
                     /locus_tag="RD486_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HDT7663135.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        17146 a         9139 c        11267 g        14894 t
ORIGIN      
        1 aacgagtctt ttagttgggc cgatgatggt tacagcggta ccgcaacatg ttcatgcaga
       61 tgaacaagga tctcaaacag ttgctgatcc tcaagcgttt atcgatcaaa tcggctggtc
      121 tgcgtcagaa gttgctgcaa gtaatgactt gtatgcttca gtcatgatcg ctcaagcgtt
      181 gttggaaagt gcatatggca cttccggatt agctagtgcg ccaaattata atctattcgg
      241 tgtgaaagga agctataacg gacaggtcgt ttatatggca accaaagaat atgtaacgga
      301 caatgggtaa cgatgaatga accattccga aaatattctt cttattggga atccttccaa
      361 gaccatgcga atgttcttcg ttcaaccagt ttttccacgg gcgattatca ttatgctggc
      421 gtgtggaaaa gcaatacaac aagtttttat gatgcaacag cgtacttgac aggtcgttat
      481 gctaccgatc caaattatgg ggccaaattg aactcattga ttaatactta taatttaacc
      541 cgttttgata cgccatcaac aggttcggct accacaagta caacaacaac gactactacg
      601 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      661 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      721 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      781 ctaaacgttt gatttagata aaaaggcaaa gaaactacca tatatggtat atctttgtct
      841 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
      901 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
      961 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1021 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1081 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1141 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1201 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1261 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1321 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1381 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1441 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1501 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1561 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1621 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1681 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1741 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1801 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     1861 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     1921 aaaaatttat gatgagaaaa attatttgaa tagagacgta aaatagtgaa cgcgactgtt
     1981 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2041 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2101 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2161 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2221 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2281 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2341 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2401 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcgagcaga ctgactgatt
     2461 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2521 caaaaaaggc gcaaatgtaa aaacagtttc tataagtgtt atacctaaaa aaagctagct
     2581 gtgtaaaaaa acgctagctt ttttattttt ttgtctttta ttcacaatct tagatatcaa
     2641 agtgaatatt atcacaataa gaatcttgta gatattgggt tcttatgctt gaaaaggaat
     2701 gaaactacaa acaaaccttt gtgaattcac aagcattaaa ctgttgtatc cgttttattt
     2761 ctgttatagt agttttgtcg aaggacaaaa tgttaatcgg agggaccata aatgaaagta
     2821 gtagtaattg gctgtactca tgcaggtact gcagctgtaa aaagtatttt aaaaaatcat
     2881 ccagaagcag aagtgacagt atatgaaaga aatgacaata tttctttctt atcttgcggt
     2941 atcgcacttt atgtcggcgg agtagtaaag gacccagcag gcttgttcta ctcaaatcct
     3001 gaagaattat cttcattagg agcaacagtt aaaatggaac acgatgtaac agacgtcgat
     3061 acagaaaata aaacagtaac ggcaaaagat ctgaaaacag gagaaacaga aacggtttct
     3121 tatgataaat tagtgatgac aactggttca tggcctatta tcccaccgat tagtggaatc
     3181 gatgcgaaaa atgtactcct atgcaaaaac tacaatcaag caaatgaaat tattgcacaa
     3241 gcgaaagaag caaaacgtgt agtaattgtt ggtggtggat atatcggtat tgaattagta
     3301 gaagcttttg tcgaatctgg aaaacaagtg acattgattg atggattaga tcgcatcttg
     3361 aataaatatc tagataaacc attcacagat atcttagaaa aagaattgac agaccgcggt
     3421 gttactcttg cgctaggcga aaatgttact gaatttatca cagatgaaga aggaaaagtg
     3481 aaacaagtag ctacaccaac agatacattt gatacagata tggtcatttt atgtgtgggc
     3541 ttccgtccaa atacaaaact gatcgaagga aaagtagata cactgccaaa cggggcaatc
     3601 aaagtgaatg aatacatgca gacaagtgat ccagacattt ttgcagctgg agactctgca
     3661 gtagtcaact acaatccaag tggcacgcaa aactatattc ctttggcaac aaatgccgtt
     3721 cgtcaaggtt tacttgtggg aaataacttg acagatcata aaatggcgta tcgtggtact
     3781 caaggaactt caggacttta cctatttggc tggacgatcg gttcgacagg tgtgaccaaa
     3841 gaaagcgcaa ctttgaacga tctagaagtc caagcgactg tatttgaaga taattatcgt
     3901 ccagagttca tgccaactac tgaaaaagta atgatggagc tagtctatga aaaaggaacg
     3961 aatcgtatcg taggtgctca gttcatgtcc aaatacgaca ttacacaatc agcaaatacc
     4021 atgtctttag ctgttcaaaa taaaatgact gtagaagatc tcgcactttc agatttcttc
     4081 ttccaaccac attttgaccg cccatggaat tacttgaacc tacttgcaca agaagcgcta
     4141 ggcgaaatcg aaactgcaca ataaagaaaa agggttgtga cacaattttg tcacgaccct
     4201 ctgtcttttt ttgtgaaaag tacaattagt tgtctttctt cgaatttttt gtcacaataa
     4261 gcagcaaaga taaagctgtt acataaaaga acaagcagct ttatttgatt ttgaaaagaa
     4321 aggtgagaaa gaagatgaat aaagaatatt ttgtccaaca agatgcattt ttagaagatt
     4381 ataaaagtgc ttcgaagaaa ttaacgatca atattgatga gttggcagat caagtactct
     4441 ctcagttgaa tgaaacgcaa gaggaatatt acacgatgcc agcaaatgac gccaaagata
     4501 atgtttctca tcgttttcct ttcagtagac gcatctactc agatgaaaat gacggcacat
     4561 tgaatacaga gtacacatat gaaggtcagc catatgtgct agaaactgat gatgatcttt
     4621 aaagacagtt tttgaaaagg ccgctcatcc ttaagtgatg acaaaaaatc atcacaatta
     4681 ccgatgactg tctctttact atcttttaat cagaaaaagg ggttatgaca agctttgtca
     4741 accccttttt ttcttggttt cagattgggt tttcctacaa aatattttta tctttgttga
     4801 ataggaaaca aaaaaacaat ataatgaaag aaaaagaagg tgtagaaatg gataaaagac
     4861 aactgctaat agaagaatat ctggatttag ctaatgagat tattcatcgt aataaaccag
     4921 aaatggaaaa agaatttgca ggatttactc taaatgaact agaagtgatt gaacatatcg
     4981 ggaaaatccc tgatcctaac gtgacaaaat tagcgaatgc tagttacatg actagaggag
     5041 ccatcagtaa gctaacaaaa aaactgatag ctagagggat cataaacact tatcaaagcg
     5101 aagagaataa aaaagaaatc tattttcaat tgacgccaat cggacaaaaa ataaggaata
     5161 gacacgagca actccatcaa aaatgggtac agcgagatgc tactgtattt gaaaatatgt
     5221 caaaagaaga atttgacaca gtatttcgtt ttatcggtcg atacagagaa tttatacgaa
     5281 gtagcaaatg aagctactat tttttattgt agtgataata ggcaaaaatc ataagcaaaa
     5341 atccgaatac cgtcggaaga aatggtgctg cagcataaag ctgtcctgcg attagcgggc
     5401 cgatgacgcg cgatagagat tgtatacttt gggtaccgcc cattacaaga ccttgctggt
     5461 tatctgagac agaattggat agttggccat tgaatacagg agtaaaaata gaatcaccga
     5521 aaccataaca gataatccca aataaaaaca aaatcggcag tagaagaatt ccagataatg
     5581 tgatgaatag ataggcgagg atttcactga acatccctat tcttgtgatc tgctgttctg
     5641 aaaatttttt gagcaatcga ggcataatga acaattgcga gacagtatcc aagattccaa
     5701 tcaaagagaa gcttaaacca accaacccag ccttccactg aaaggcgtca atcgaaaatt
     5761 gagaaaagat agattgaaga gagccagctg ccaaccaaac agcaaaacct gctgtcaata
     5821 aaggaataac ggatgaaatc ttgaataatt gttgtaattg gtgaaaaggt cttacatggg
     5881 agaaacttaa atctactgaa cgttttttta ttggaaggct ttctagcata aatgtgtagc
     5941 cataaacggc atttaagaaa gtaaagagtg ctccaataaa tataggaaca gaattcccca
     6001 actcagctaa tagaccccct ataataggac ccagcgttgt tcctataccg actaaagcac
     6061 ccatccatcc aaaaactttg gttctttcat taggttccgt gatgtcggca aagtaagcat
     6121 ataaggtgga gatttctcct gccgtcaatc cttcaatgat acgaccaagg aacaacatcc
     6181 atatcgaatt tcctaaacca aaaagcaaat atccgatact tgatcctaat aaactgataa
     6241 taaggatcgg atgacgccca aaatgatcac ttaagctacc gagaatgggg gcagataaga
     6301 aggcagctag agcataaaca gacatgagca aagtgatata gaaagcttgc tgatgtatgg
     6361 agtgagaata aggcagcgtt aaaaacggaa gtacaggact gacgatagta aatcctaatc
     6421 cagtgaataa gacagagacg tatccaaaaa ctttagaatg tttatttgtg aaactgtaca
     6481 tgtaaaaact cctttatgca ataatgttaa cttggaaaca aaaatagtgt atagtaattt
     6541 tgtttccttg tcaacattct aaggaacagc gaaatctact taatttattt attccgaaaa
     6601 gtgaagatac gcatcaaaaa catgaacaaa caaaaatcaa gtagacgaca ttgtaaatct
     6661 gaccgatcag tgaagtaaat agaaaagaaa cctgttcttg cttcccatgt tttttttacg
     6721 tatactgtga ttgagcggag gagaaatcat gttgaattta gaaaattact taagcgctgg
     6781 acaaacagtc atatctaatc ttttacttaa aaattatcat aggatcggtc tacaatctga
     6841 agaattttta tttgttctac agttgcatat ggcacagctt gaaggagata ctttccctga
     6901 tttgcagatg attgctatgg atatgggaat caaacaagat cagatttttc aaatactgga
     6961 tcgtctcgta acaaatggat ttatcaagat agaaacgacg attgtcaacg gtaaaaaagc
     7021 agatcgatat aatctttacc ccatctatga tctattaggt gagtatttaa aaacacaaga
     7081 aaaaaaatac gaagaaaaaa cacaagaaaa agaaatccag tcagtgtatc aattatttga
     7141 acaagaattt ggacgcccgc tttcttcgat cgagttccag cggatcggac aatggctaga
     7201 agaagaccat tatcagccgg aaattttgaa gctagcactg cgggaagccg tattaaatca
     7261 ggcttatagt tttaattacg ttgaccgcat tttgctatcg tgggaaagaa aaaatctacg
     7321 tacaaaacaa caagtggaag aagaccaaaa acgaagaaaa cagcagcttc ttcaaagaga
     7381 agtagaacag tcagctcaac aagaagaatt gccgaaagtc tcactgaaaa attggttgga
     7441 ggagtagcgg aatatgttaa gcaaacaaaa aacaatggaa gctctagaaa cgatgtatgg
     7501 aatgtttccc gaagcacatg gagaactcaa gcacaataat ccatttgagt tattgattgc
     7561 agtgatctta agtgcccagg cgacagatgt atcagtgaat aaagcaacgc cagatttgtt
     7621 tgcctctttt ccgacacccg atgcgttagc agaagcttca atcgatgaaa tcattcttaa
     7681 aataaaaacg attggtttgt atcgaaataa agcaaaaaac atcaaagcgt gtgcacagca
     7741 gctgattgaa cgtttcgatg ggcaagtgcc aacgtcaaga gaagaattga tgtctcttcc
     7801 tggtgtaggc agaaagacag caaatgtcgt attgggggat gcattcggga taccagcaat
     7861 cgcagtagat acccacgtgg aacgtgtctc aaaacgcctg aggatctgca aactagatgc
     7921 tacggtcatg gaagtagaag aaacactgat gcggaaagta ccacaagaat tatgggtaaa
     7981 gacacatcat acactgattt tttttggtag atatcattgc acggcaagaa atcccaagtg
     8041 cgaggtatgt cctttgctat caatatgtca agatgggaaa aatcggatgc gtctaaaaga
     8101 aaaggcgcta aaaaagaaac cacgcctgta gacgtggttt ctttaattgc aaataaatgt
     8161 atgaattatc ttgttattat ggagaaaagc tgtttcgttt atcttttttg catgaaaaag
     8221 taaatgtaca tactcagtag ctaggatggt aacttattac aatttattgc gataaaaata
     8281 aaagttgtta tttttattgg gaaaataccc gatgtagaaa ataatgcctt ccaatatacc
     8341 tataaaataa gtccagtatt ccaaaggatt atataaataa gtgacgtatc tatctaaagg
     8401 tgtaataaaa atgataagtg ataataaaaa aataccattt ataactaaac ataaactaat
     8461 ggatttgggc ggtttcaggc tcatcagaaa aatatagatt ctggtgaaca acaaccataa
     8521 aaaagtgaga atcattgcat gagagcttct ttccataaat tttcctttaa gagtagtgct
     8581 taaaagtaca gaaaaaataa taaatgcaag gataggagca attaaagtaa atttatttaa
     8641 taataaacaa aatttttcag cttttttatt cttggaataa cgaggtattg ttttcgataa
     8701 aaaaagatgg tgcagacaaa ttatgataat taagcatact atcagataac tcaaaatgaa
     8761 gccttctttc aaaaaattat tcaaaaccat atattgtatt ttttatttga taataacaat
     8821 gggattatta agaagtggca ctaaataaaa gactagtgtg tatttagccg atttaattat
     8881 aaacaagtaa atggataaag tatatgtaat gataaaagaa aaatggattt tctaattttt
     8941 aagctaaatg ttagatcaca catgtatatg ctggatagtc ttataaaaaa tcatgtaata
     9001 cagcttggta catgattttt atttgtagct gttttttaca tagacacaaa aaagaaacca
     9061 cgcttgtaga cgtggtttct tttttactat ctgtttccag aagctgaggt gctgctggat
     9121 ggtgtatggt catttgcagc atccgctccg ctagttgctg gctcactgga agaagcagga
     9181 ggagcagatg aagacggtgt cgagctttct tcggatgaag aagaaggaac cgttgttgaa
     9241 gacgctggct cgcttgtttc tgctgtcgtg ctttcttttg aggactcagc agttgattcg
     9301 ctttgactag tagagctaga gctttgagtc gttgtctctg ttgttgagct tccaggagtc
     9361 tggacatagc tggaagatgg aatagttgtt gatggtgtaa ttgcattcga tctagctgta
     9421 tattgatctt tgtagtacag ttcaccgccc acacgaatta atccgcttgg catctcccag
     9481 tctgtatttg tcacgttagc tgaaacatac tgcataagct cgcgataaac atcagaggct
     9541 acgtgtgacg attctgaagt gacaggtgtc atttttttat tgtaacctgt ccacacggaa
     9601 atcgaataat ttggcgtata gcccgcaaat aggatatctg gatacacccc agaagaaata
     9661 ccaagttttg catactcgtc atctgtgtaa ttggatgttc cggtcttacc ggcttgatat
     9721 aacccagcga tttgcgcatt cgtaccagtt ccttcagtga tcgtatcttt taaaatgtct
     9781 gtgatcatat aagctgtttc tggagacatg gctgtttttc catctggctc ataagtttct
     9841 tctgttccgt cttggaagac gattttatta acatattgag gtttgtaata agtccctcca
     9901 ttggcgaaag ccgcataggc tgctgccatt tttaaggaag aagctccgta ttttgtccca
     9961 tcttgttctt ccgtattact agagatcgca ttcgattgat ggatcgtact gtattcgatc
    10021 ccaagatttt ttaagaaaga agccacttta tctgaaccga cttcattgaa taatttgact
    10081 gctggaacat tacgggataa gtaaagtgct tggcgtaaag taatggtgcc catatattga
    10141 ttatcccagt ttcctacagg agtcgaagtc ccttcatagt tatacggtgc gtcagtaata
    10201 gtttttccag tagaatattt caaatattca aaagctggtc cgtaatctgt gacaggtttc
    10261 atcgtagaac caaaatcacg ggaagtattc actgctaagt tgttgcctaa agttacgtct
    10321 tctgcgatgt gacgtccgcc aatctgggct tttactttcc cggtattggt gtcgataagg
    10381 gtggaggcaa cttgcatctc gtcgtctggg taagagacat actgatccgt gttgacgata
    10441 tcatatagtt tcttttgggc gtccagatcc aaattcgtat aaatctctaa accgtctgtg
    10501 tagacattct tatctgtttt ttcttgtact tcattgatga cttctttgac ataattatcg
    10561 acgatcttag tattgtcatc ggattgagtt agttcttgca gaccatccgt taccggtaca
    10621 ttaacagctt gatcatattc tgtttgagag attttttcgt tttgaagcat cgtatacaaa
    10681 acagtatctc gtcttttctt cgcctgatct ggataaacat aaggatcata ggcggaaggg
    10741 gcttgaggca tcccagcaag caatgctgtt tgcggtaaag aaagttctga taatttctta
    10801 ccaaagtaca tctcagaagc tgtctccatc ccgtacaagc cgtttgacat atacacttta
    10861 tttacgtagt aggtcaagat ctcttgtttc gatttttttt gttccaatct tacagccatc
    10921 cacgcttctt gggccttgcg tttcagagtc tgatcctcgg cactggtgga gaagaaggaa
    10981 agtttgatca attgctgtgt caaagtactt ccgccttgca gtccgccaga ggtaaagtta
    11041 gagagggcag aaccgatgat ccgaataggg tcaaccccga tgtgtttata aaaacggcga
    11101 tcttctaccg acacgatcgc atcttctaat gttttcggta attcattcgc agaaattttt
    11161 tcacgctttt ctgcgcctaa atcttcgaat agttcgccat cttgtgtata tagtttggaa
    11221 gatacggtag cgtctaattt tttatccgtc aattcgggcg catcttttgc gtaataccag
    11281 aaaagtccta cacctgctaa aaagaggata cagaaaaatg agagtattcc taaaaggatc
    11341 ttgataaata atcctttttt atgtgttcca gaggactttc cagaaccttt gccagaattc
    11401 ttcttcacac tctttttagg agtaggctgt ttctgtcgtc tagagcttct agtttgttca
    11461 tttgccattc ttgctttctc cttcaataga taatgttgat aaatagaagt caaccgcgtc
    11521 caaataagga atccgcggag aaataccagt tttgatctct attcctagtt cttcgatcaa
    11581 agataaaggt agtgatttgc gtcctttttc cttttgggcg tcccagtaag caatcaaatg
    11641 aacactattc aaataaaaac agcgcttcaa agacgaaaac cataacaaga caaagcagac
    11701 cccattttgt tcgaggcatg ctttcatatg ttcgatttga tgggcatgga agtttttaaa
    11761 gggaaaagat gttttgttct tggtttcttt tgcttcaaag tccaagtaaa agcctcgata
    11821 gacgccatta tagtctgtag ttgaggcttg ggtaaagtag gcttccttga tcacagcagc
    11881 acttctctta ggatagtcta ctttcacgat ttggataggg gtaggctttt tatggataac
    11941 cgccaacccg cgggaaagat aatatttatt actttcattg attgcttctt caaagcgcat
    12001 cccccgattg ccgaattcag tgatctgatt tcttttttct tgaatttttt cgacgggaga
    12061 ggcattctta taataaggtt ggccatttgg atagcgcaat accatcttta atcacactcc
    12121 taggccacat tatagcaaaa aagcggatag aaagaaaagg aatctgagat ggataagtca
    12181 aaagtaatct atgtgtctgg gtatcgaagt ttcgaactcg gtgtttttaa agaaaatgat
    12241 cctaaaatcc aagttgttaa aaatgtttta aaaaaagaac tccatcagtt agcagaagaa
    12301 gggctggaat gggtacttgt cagtgggaat ttgggcgtcg aactatgggc tgtgcaaata
    12361 gtagcggaat tgaaagaaga atatccggaa ctatctcttg gtattttgta tcctttttct
    12421 gattttggta ataactggaa tgaagggaac caagaaaaaa aacaattagc agaacaatta
    12481 gcagattatg tcgaagctgt tagccatcaa ccctaccaat cacctagtca gctaaagaat
    12541 cacactcgtt ttatacttga gcatacagtg ggctgtctgc tgatctatga tgaagaattc
    12601 cctggaaaaa cgaagtattt ttttgaagat gcacagaatt accaagcaga tcatccctac
    12661 gaaattcggc tgatcagtat ggacgatctt caaaatttta gtgaataatc gatattgtgt
    12721 ttgatttatc aacttttttc ctatacaatg aaaaaggtag aaatgttatt acgtaaatga
    12781 aaactagagg tgtaaatatg gcgaatttgg tttatagtcc taaagacatt ttacaacaag
    12841 aattcaaaac aaaaatgcgc ggctatgatc ccgttgaagt tgatgaattc ttagacaata
    12901 tcatcaaaga ttatgaaact tacagcaaag aactccttgc tttacaagaa gaaaacgatc
    12961 gattgagtgc aaaagtagct caattatcta aaactcaagg agcagctcaa acacgcgtgc
    13021 aacaaacaga ggcaccaaag agcgcagcag tgaccaattt tgatatctta aaacgcttgt
    13081 caaatcttga acgtgaagta tttggtaaaa agcttgatca acaagcaagt gcagtcaaac
    13141 cagcacaacc taatccaaat aactacacaa atgcagacac aagcttagat gataatgaaa
    13201 aaacacgtca attttaattt ttgattaatg aatttgcggt tttcgggtaa tcgcggtctg
    13261 acttgatcag gctgaggaaa gtccatgctc gcacaggctg tgatgcctgt agtgttcgtg
    13321 cttagcgaaa ccataagcta aggtactctt tggagtaacg gcaggaaaac aagctaaggc
    13381 ttcggctatg cttaagtatc cttgaaagtg ccacagtgac gaagcggctg gggaaaccca
    13441 tccggtggaa cgcggtaaac ccctcgagcg agcaacccaa acaatggtag gggcgctttt
    13501 tgtctggaag aagaacagga caaaaaggca gtataactgc agatagatgg ttaccgcttt
    13561 gttttttctc cctggaaaag caaagtacag aacatggctt atagaaaacc gcaaacatca
    13621 gggaattagg tcgtgacaaa agtaatgcgt tataagaaac aagaaaaaca tttgaaagct
    13681 atttttcaat acttcagatg aatcgttctt attacaaaac aaacttttgt atcaccggtt
    13741 attcggaatt tgagtaaaag tgtggggtag gactgatgtc ccacctcctt tttttataaa
    13801 taaggagatt gtgtatggaa aaaaacagga agttcaacct cgtcgcaact gcggcaagcg
    13861 ggctagaagc actggttggt aaagaattaa gagatcttgg aatcgaatgc caagttgaga
    13921 acggacgtgc acgttttgaa ggaacaatgg aaacgatcgc tacagctaat ttatggttac
    13981 gtacagcaga tcgagtaaaa atcgtggttg gggaattcga tgcgtatacg tttgatgaat
    14041 tgtttgaaaa cgtaaaagca ttgccttggg aagattttct tccactagat gcagcttttc
    14101 ctgtagctgg aaaatcgatc aagtcgaaac tatatagcac acctgattgc caagcgatca
    14161 caaaaaaagc aatcgttgaa cgtctccgta cctattatca ccgtccagct tctgtaccac
    14221 tgacggaaac tggcgcacat tttcagttgg aagtagcttt gctgaaagac catgtgatgg
    14281 taactctgga tacgacagga ccaagtttat tcaaacgtgg ttatcgctta gaaaaaggtg
    14341 gagcaccatt gaaagaaaac atggcagcag cacttattat gttgacaaat tggcgaaaag
    14401 accgtccatt ttatgatcct gtatgtggtt caggtacgct ttgtattgaa gcagccttaa
    14461 taggccataa tatcgcacca ggattcaatc gtgagtttgc ttgcgaatct tgggattggt
    14521 tcagtcaaga aatcatggaa aatgttcgat cagcagccga agaaaaagca gattatgata
    14581 ttgaattaga tattactggt tcagatatca atggacggat gattgaaatt gccaaagcca
    14641 atgcagaaga aatcggatta ggctcttcga ttacctttaa gcaacaagca gtcaaagact
    14701 tcaaaacgga taaagaatac ggggtcatcg tggctaatcc gccttacgga gaacgtctag
    14761 gagaagaaga aactgttcgg aaattatata aagaaatggg cgatgtattc cgtccattaa
    14821 aaacatggag taaatatatc ttgactagcg acttagcgtt tgaggaattt tacggacaaa
    14881 aagcaaccaa aaaaagaaaa ttgtacaatg gtgcattgcg tacggatcta ttccagtatt
    14941 ggggaactcg tccgcctaga aaaaaagaga aagacgaata atcttactaa ttgattcatt
    15001 caattggatg tttggaggaa tagggaatga aagaaaaaga gtttttacaa gaagtaaaag
    15061 aaatcaatct tctacaacaa gctttaggaa tcctcgattg ggatacacaa acaggtatgc
    15121 ctgaaaaagc tagtgcatac cgaagtgaag tagacagcta tctttacagc atttattttt
    15181 caaaaaaaat cggtccaaaa atcaaagaag ccattcgcta tttttctgaa catccggaag
    15241 aattgtcgga agttggaact gccgtttttg ccaaagtaaa agaagagtat gatttggaac
    15301 atcgcgtacc ggaagatctt atgagaaaat atacagctgc cgtttcttca gcacacggac
    15361 aatggcaaaa agctagagaa acacaacaat tttctgattt tcaacacgca ttgaatcaaa
    15421 atattgaatt aacaaaacag ttgatacctt actggagaaa agatgaaaag acgaattatg
    15481 atgttttgct gaatcaatac gaacccggga tgactgtcga aatccttgat aaggtatttg
    15541 atcagcttaa agaaggaatt ctttcgatcc gccgtacgct ccaagaaaaa gggactgaac
    15601 ctgaaacaga ctttttaaat cggagaatga cgaaaaaaca acagaagaga tttgtagtga
    15661 aagtaatcga acaacttggt tatgatttta gtcgtggtcg tttagatgac actgtccacc
    15721 catttatgac tggaattaat ccgaatgatg cacgaatcac gacacgatgg aacgaaacag
    15781 atttcaaaat ggctgttttt ggagtgatcc acgaggctgg tcatggtatg tatgaacaag
    15841 acatcgatga taaatatgcg tatacaccgg tttatgaagg tacatcaatg ggtatccatg
    15901 aatcacaatc gttgtttaac gagatcatta ttggaagtag tcgcagcttc tggaaaaagc
    15961 aatatccttt ctttcaagaa tgtgcagaag gaacattcga tgatattcct tttgacaaat
    16021 tttatcgttt attgaaccat acaaaatcaa gtttggttcg tatcgaggca gacagtttga
    16081 cttaccctct ccatatcatc attcgttatg aaatcgaaaa aatgattttc aatgaagggg
    16141 tagatgttgc tgaactacct gaaatatgga atcaaaaata tgaagagtat ctgggaatac
    16201 gaccaacaaa tgatgtggaa ggcatcctac aagacgttca ttggtcaggt gcaagctttg
    16261 gttattttcc ctcttatgca ttagggtaca tgtatgcggc acaattactt cattctttgc
    16321 agcaagaaat agatgtggaa aatgttctag cgtcagacga ttattctcca atcaaaaact
    16381 ggatgtcaga gcatatccat caatatggtg catctagaaa accaaatcaa ttaatcatgg
    16441 atgcaacaca tgaaccgctt aatccgcaat acctgatcga ctatatgaaa gacctgtatt
    16501 ttaatgtata tcaggtaaaa taaaatacaa tttacaaaga tagctgaaat tcatctaatc
    16561 tatagatgtt ttcagctatt tacttaagaa agaagtggaa cgaatggata aattacaagt
    16621 gatcgctgat tatagtatgg accaattagc gcatgatcaa acaggacatg ggagcgatca
    16681 taccaaaaga gttgtcaagt tagctgaaaa aattttggag acggaaccgc aggcagaccg
    16741 ctttgtgacg cttgcagcag cttacctaca tgatacgatt gatgataaag tcgttaaaaa
    16801 tgagaacgag gcaaagcaac agcttcgtgt attccttcgc tctttgccaa tagtagagga
    16861 acagatctcg atgatttttt ccattatcga aaatatgtcc ttttctaaaa atctctctga
    16921 agcggccgaa ctatctctgg aaggtaagat cgttcaagac gctgatcgta tcgaagcatt
    16981 aggagcaatc ggcattttgc gtactgctta tttcggcggt ggacatgggc acccgatttt
    17041 tgatcctgaa ctgtatccgc aaacattcaa ggacaaagaa aattaccgaa aaggcacgac
    17101 agtgatcaat catttttatg aaaaactgtt cttgctgtct gataaaatga atactgatta
    17161 cggatatgaa gaagccaaac gaagagaaac cttcatgcgt gaattcttag aagaattttt
    17221 tctggaatgg tctattgacg atgaaaattt tactccagac aattggatca aaaataacaa
    17281 aaaatgatgg aggttgtgac agaagtggtc agctccaaga tatttcggat cattttccgt
    17341 aaaagttact tctggaacac tgtttaccaa gaggtcgtga gcctgccgtt cagctccgag
    17401 tcacaaggaa caatttcaaa aaatagcttc tcgtgtttga tgaatattgt aacttgtgat
    17461 tcggaattgg caggagaaca ccgtttattc ggaagaatag gactgtgaca agacttttgt
    17521 cacagtcctt ttttcgaatt caacaagtaa aacttttaag aaatattcag agagtaaaat
    17581 taaaaattgc tgataaacga agatggaaat tttatgtatt tttattggtc tatgcaataa
    17641 ataaattaaa tattcagaat acaattgatt ttaacgaaag ggcttctatc aatggttgtg
    17701 ttgtatttat ctgcccaggt agagtaaaat agatcattat ctaaaaggta attgttcata
    17761 ctatataagt catttgaaag taaaaagata ctgtaaataa aaaatgtggt taaataattc
    17821 tcataatcag tgtaagcgtt atcaaaaata tagcatactt gctttgtaga tgaatgacac
    17881 gatatatgtt tggtatgttc tgcaagacag atgaatatgg aggtggagac aatgtcttcc
    17941 aaagaactaa caatgtattt agagaaagaa ttggatcaac tgaaagaaaa ggggttatac
    18001 aatacgatcg acatactaga aagtgaaaat ggtgcttgta tcatcgtaga cggaaaaaag
    18061 atgatcaatc tagcatccaa caattatctt ggatttgcca atcgcgaaga attgaaaaaa
    18121 gcatgtattg aagcaaccga aacttatggt gtaggagcag gagcagtccg aacgatcaat
    18181 ggttcgctga aaatccatca gcaattagaa gaaaaaatcg cagaattcaa agggacagaa
    18241 gcagcaatcg cctttcaatc tggattcaac tgcaatatgg gcgctatctc tgcagtaatg
    18301 acaaaagaag atgctatctt atcggatgaa ttaaaccatg catctattat tgacggttgc
    18361 cgcttatccg gagcaaaaat catccgaatt aaacatcaag atatgaaaga ccttgagaaa
    18421 aaagcaaagg aagcgataga aagtaagaaa tataaaaaaa tcatgtatat cacagatggt
    18481 gttttctcca tggatggaga cattgcacga ttgccggaaa ttattccgat tgttgaaaaa
    18541 tatggactga tcacctacgt cgatgatgcg cacggctcag gcgtaactgg aaaaggtgca
    18601 ggaaccgtca agcattttgg attaagcgac aaaatcgata tgcaaatggg cacgttatcg
    18661 aaagctatag gtgttgttgg gggttatgta gctggatcga aaacactaat cgactggttg
    18721 aaagctagaa gtcggccatt cctattttct acttcgctaa ctccaggtgc agctgcagct
    18781 gcattggctt cgattacttt gatgcaagaa catccggaac ttgtcgaaaa agtttgggaa
    18841 aatgctaatt attttaaaga agaattgaaa aaagtaggct ataacatcgg tatgtctgaa
    18901 acacctatta ctccagtcat tttgggagac gaaaaagtga ctcagacttt ctctaagaag
    18961 ctgatcgaac atgggattta tgctaaacca atcgtttatc caactgtgcc tcttgggaca
    19021 ggcaggatca gaaatatgcc gactgcggaa catacgaggg aaatgcttga tgaagcagta
    19081 gcagtttatc aaaaaatagg aaaagaaatg gaaattattt aactaaattt agttttttcg
    19141 tctatttaaa attagagaac atgttcacgc atatattgtt aatcatctga agatagtagt
    19201 aaaaaagatc agggaggatc atcatgaaaa aagtattggt gacaggatgt ttaggacaaa
    19261 ttggttcaga gttgatcaca cggctacgtc aagaactagg cagtgaaaat gtcattgcga
    19321 cagatatacg catgcctgaa gtcattgaga aaaacgatat ctttgagatc ctagatgtaa
    19381 tggattacga aaaaatgcgc agcatagcag aacaatatca agtggacaca ttgattcatt
    19441 tggctgctct tttgtcagct gttgcagaag caaaaccaca attagcctgg aatttgaacg
    19501 tgactgggct ggtcaatgca ttggaagtcg ctagagaatt ccagctgaaa ttttttacgc
    19561 caagttcaat cggcgcgttt ggtccaaata ctccaaaaga tcatacccca caagatactc
    19621 ttcagcgtcc tacaaccatg tatggggtaa cgaaggtagc tggagaacta ctatgtgatt
    19681 attattatgt gaaatatggc gtagatactc gtggtgtccg tttccctgga ttgatttctt
    19741 atgcaacctt gccaggaggc ggtacgacag actacgcagt cgatatttat tattcagcaa
    19801 tcaaagaagg aaagtacact agtttcattg atcaaggtac atcaatggat atgatgtata
    19861 tgccagatgc gatcgatgcc attataaaac tcatgaatgc agatcctgat cgattggttc
    19921 atcgaaatgc cttcaatata tcggcgatgt cttttgaccc ggaagagatc aaagcatcta
    19981 ttcaaaaaat cataccagat tttgaaatgg attatgatgt ggatcctgta cgtcagtcaa
    20041 tagcagaatc ttggccaaat tcactagatg tttcttgtgc gcaagaggaa tggggctttt
    20101 cgccgaaata cgacttagat gtgatgacaa aggatatgtt ggaaaaactg aaagaaaaat
    20161 tggtagagac ggtataaaac aagaaccaca tccaaaaagt tttttatact tttgggattg
    20221 gctatggtat gaaaggggac aagggatgga agaatatcaa gccacgccag taaaagaagt
    20281 aaaaatagaa aatgaattaa aacgtacgat gggatttttt actgctttat cgactgttat
    20341 gggcacagtg atcggtgcag gggtattttt taaagccgca agcgtagcag aagttacagg
    20401 atccgccagt ttgcatatgt tttcttggtt tctcggtggt atgatttctg tctgtgcagg
    20461 actaacagga gctgaactgg cagctgctat tccagaaaca ggagggatga ttaaatatat
    20521 cgaacggatt tacggaaata cagcagcttt tttattgggc tgggcgcaag tcgtgattta
    20581 ttttccagca aatgtagcag ccttgtcgat cattttcggt acacagttcg tcaatctatt
    20641 tggtctttcc cagtcaatga ttgttcccgt agctgttaca gctgctgtat cgatcctgtt
    20701 gatcaatttt ttaggttcta aagctggagg ggcttttcag tcgattacgc ttgtctgcaa
    20761 gcttattcct ttgtttgtga tcgtcatttt cggtttgttc cgacaagaag gagtagactt
    20821 ccaactgttt ccgatccaag caggagaaaa tctttcattt ttctcagcct tgggagcggg
    20881 cttgctagca acgatgttcg catacgacgg ttggatacac gtaggaaata tttcgggaga
    20941 attgaaaaag ccggcgaaag atttgccaaa agcaatttct ttaggaatca tcggaatcat
    21001 gatcgtttat ttattagtaa atgcggtgtt cttaagaacc gcatctatcg acggagtcgc
    21061 aggaaacagc aatgcggcaa gtgacgttgc aaaaatgatt tttggcggct tcggtggaag
    21121 actggtcaca gttggtatct tgatttctgt ttatggaacc atcaatggct atacccttac
    21181 tggaatgcgt ctcccttatg ttatggcaaa agaaaacaac ctgcctttta gcaagctctt
    21241 tgctaaactt catgataaaa ctaaagttcc tgtagccgca ggtatcttag agctagtcat
    21301 cgctattggc atgatgatga tcggtggttt tgatacacta acggatatgc tgatctttgt
    21361 catttggatt ttttatacga tggtctttgt tggtgtcatt cttcttcgta aaaaagaacc
    21421 tgatttgttt cgaccataca aagttccaat gtatccgttt attccactag tagcaatcat
    21481 tggagggact tttatcgtat caagcacgct tatcactcag acctttttag cttcgatggg
    21541 gatagtattg acacttgctg gtatcccgat ttatctctat ttaaaacgta gatagctaaa
    21601 acattcgaat tttattagaa ctgcacttct ctgccaaaca aaatatttta tttaaatgag
    21661 gagtacgtgg aagaaatgtc aaaagtactc gttaattttg atcacgtaaa tgtcgttttg
    21721 tctacgatga aatagcaaag taaaagacag aaatcgggct caaccgattt ctgtctttta
    21781 ctttgatttg cgtaactgaa ctattcggcg tacgccgcga taaatattta ataaaaccaa
    21841 gcaaccagaa atgaaaatgg gaagccaaat cagatagaca gggtagccaa gcactttaga
    21901 caaagcatgt ggagtcattt tatccatttc aagaagtgct tgctgccaag tctgaagatt
    21961 gaagactagc atgaaacccg aaataatcag gagaataaat cctaaataat gaattgtagt
    22021 tctttttctt acataagcga tcgtagcata aaggaacagt aaaaaaatag gtacgccaaa
    22081 aacaaagtac atattcagca tctcgacacc ccctttgtgt ttatcttact ttactttgaa
    22141 agaaatgaga aataatagcc tcgttacttg cttgaaacag caaaggactg ctaagataag
    22201 agagatacaa agaatcaagg aggagtcata tggcaagtta tatcgaaccg attcgttttg
    22261 cgctgattgt ttttccattt ttagccttag cgatctcatc tgtttttttt atttatgaat
    22321 atcgaaagta tggaacattt ctagtaacaa gggcagttat tttgtattct ttcgtttttt
    22381 atttattgtg tgcgtatttt ttggtgatct taccacttcc ggcaaaggag acggttgccc
    22441 aaatgacagg gccaaagatg gagctgcatt tatttgcttc atggcaacat ttcagagaca
    22501 acacggtatt ggtcttgtct gaacctagta cctacctgcc ggcaatgaag cagagtgtat
    22561 ttttggaacc agcttttaat gttttattac tcataccatt tggcatttat ttaagatatt
    22621 atttccggct ttcttttatg aaaacgatga ttgctagttt ctgcctttct ctattttttg
    22681 aattgacgca gctaagtgga ctttatttta tctacccaag accataccgc ttatttgatg
    22741 tgaatgattt agtgacaaat acattgggtg gaatcattgg ttttgtcgtt acgccgttat
    22801 ttacatttat gcttcctaca agaagacgaa tggatgaact ttcttatgaa aaaggaaaga
    22861 ctgtctcatt gactcgacgc ttggtcgctt atttgatcga ctggacattt ttatctctta
    22921 ttaatttggt agcggcgatt ttctttaaaa ttgcgttcga ttcaggggca gttacttctc
    22981 atatctggtg gcttttatta gaagtagggg tatactttat gattgtaccg tttataacca
    23041 atggatggac acttggcaaa aaaattgtgc gtatccgttt ggtggaagaa gaccgcgaac
    23101 gaatttcttt aaaagcattg atgatccgct acgggtatct gtactttctt ttttatggtt
    23161 taagctggtt ggggcagttg cttcagcaaa tcatgaattc gacaacgaat acggtgttgc
    23221 agatgagtgc agtattcatt tctctcggtg tcttgttact acaaggtatt tttattttaa
    23281 atatcttgct atcatttttg agaaaaaaac ggattctgtt ttatgaaaaa gctagtcaca
    23341 catatactgt tagcacgatt ggccaaacaa aggatgatga ttctcgaaat tagctgagca
    23401 aaaacgcttt gtctgtgtta taatgccaaa gtcgtgataa tttaaagaga agaggtgcac
    23461 gaatgaataa ttttgatata ttccgcttca aaccgtttat caatgaagcg ttaaccgcaa
    23521 agggcttcaa acagcccaca gaggtccagg aacgtttgat tcctttaatt gcaaaaggaa
    23581 aaaatatcat tgggcaatct caaactggta caggaaaaac acatacgttt ttgttgcctt
    23641 tgtttgaaaa aatcaatgca gaaaaagagg aagtacaagt tgttattaca gctccaagta
    23701 gggaactagc tgcacagatc tatgaagcag ctacacaaat cgctaaattt tctacaccgg
    23761 agatccgtgt ctcgaatttt gtcggcggta cagacaaaca gcgtcaatta aatcgtctgc
    23821 atcaccaaca gccacaggtt gtagtaggca cgcctggtag aatattagac atgatgaatg
    23881 aacaagcgct gaagattcac accgcatttg catttgttgt cgatgaagcg gatatgacat
    23941 tggatatggg ttttttaaat gaagtagacc aaattgcaag tcgattacca gaaaagctgc
    24001 agtttttagt tttttctgcc actattccag aaaaacttcg tccattctta cgaaaataca
    24061 tggaaaatcc aatcattgaa gaaatcaaac caaaagcagt tatttctgaa gacattgaaa
    24121 attggctgat ttcaacaaaa ggtaaagatg agaatcaaat gatttatcaa ctgctgacaa
    24181 ttggtcatcc ttatttagca atcgtatttg ccaatacaaa acagcatgtg gatgaaattg
    24241 ccgattactt gaaaaaccaa ggcttgaaag tagcaaagat tcatggagac atcaccccaa
    24301 gagagagaaa acgagtgatg cgacaagtac agaatctgga gtatcaatat gttgtagcga
    24361 ctgatttagc tgctagaggg atcgatatcg aaggtgtctc tcatgttatt aatgcagaaa
    24421 ttccagaaga tctagacttc tttatccatc gtgtcggacg tactggacgt aatggcttaa
    24481 aaggaacggc cattacgtta tattcgccaa atgatgagca agccattgat gcgatagaaa
    24541 aattgggcgt ctcatttgaa ccaaaagaaa tcaaaaacgg ggaaatcgtc aaaacatacg
    24601 atcgtaatag acgtgccaaa cgagaaaaat caaaagatgt attagatccc acgctgattg
    24661 gtcttgtgaa gaagaaaaag aaaaagatca agcctggtta taagaaaaaa atcgattggg
    24721 caattgcaga aaaaaataaa aaagaacgca aaatcgaacg cagacagcaa agccgtactg
    24781 ctcgtaaaaa taagaaaaat tcacataaat aaaaaacaag aggttgtgac aaaaggcgtg
    24841 tcacaatctc ttgtttttaa gctagacttt ttttcattcc gatacaaagt acttcatctt
    24901 caataaaagg ttctgtgcaa gtatgatacc cttgtttttc ataaaaatct acagccgtca
    24961 tttcagctac tacataacta gtctgacaac cttctgaaac cgcccgtttt tcagcagctt
    25021 caagcaactg accgcctaac ccttttcctc ggtattcttt tgctacgcaa aatcgttccg
    25081 gcttgaagca agtaggtgtt ttcttttcat aacgcaaagt agctactggt cttttttgat
    25141 caagaaatag ataataggtt tgttgcggga tatcttttcc gtcgaattct agttctgcag
    25201 gaatcccttg ttctaataca aaaattgata tctcaaaaag cagctagctg cgcgtatcca
    25261 ttcatccgct ccaactattt ttttcatcat attcctcctt gtcatgaata gcagagatgt
    25321 attgattcct ttattcttat cgtaccaaaa atcgtggagt atgaccaaaa ggaaatgaaa
    25381 ataaaaattg agatattgac agtgatcaat agaatgcgta tactaattaa gtacgaaaag
    25441 gatatgattt gttttttaag actcacagaa aattctttct tggctgaaaa aagaatagtc
    25501 actaatcaaa ttgctccctt tttctatttt ggtagaaata ccgacgcagc tcagcgttat
    25561 cgagtttaag aggtaatgat tacacatcat tgcaatcaag gtggtaccgc gagttttcgt
    25621 ccttggctgt gatggtgttt ttttgtattt aatttataga aagcaggtaa tgacatgaaa
    25681 caattaagta gtgcacaagt tcgacaaatg tttcttgatt tcttccaatc taaaggacat
    25741 acgattgaac ctagtgcgtc tttgatcccc gtgaacgatc caaccttatt gtggatcaac
    25801 tctggtgttg caacattgaa aaaatatttt gatggttcag ttgtgccaga aaatccaaga
    25861 atcacaaatg cccaaaaatc tattcgaaca aatgatatcg aaaatgtcgg taaaacagca
    25921 cggcaccata cgatgtttga gatgctgggt aatttttcga ttggtgacta tttcaaaaat
    25981 gaagccatcc actgggcatg ggaatttttg actgatccaa aatggatggc attcgatcca
    26041 gaaaaacttt atgtaacagt ttatccaaaa gatacagaag caaaacgcat ctggcatgaa
    26101 gaagttggcc tgccactaga tcacattatt gatgtagaag acaacttctg ggatatcggt
    26161 gcaggcccat gtggtccgga tacggaaatt ttctatgacc gtggagaagc ttataacgat
    26221 ttagcagaag acgatcctga aaactatcca ggaggagaaa atgaacgtta tttagaaatc
    26281 tggaacttag tattttcaga attcaaccat aagcctgata acacatttga accacttcct
    26341 cataaaaaca ttgatacggg gatgggattg gaacgcatgg tctcaatcgt tcaagatgcg
    26401 tcaacgaact ttgagacaga cttgtttatg cctattatcc acgccgtaga aaagctaagc
    26461 aaacaagtaa aatatggtga aaacccagta acagatattt cttacaaagt aatcgcagat
    26521 catattcgcg ccctttcatt tgctattggc gacggtgcat tgccatcgaa tgaagggaga
    26581 gggtatgtct tacgccgttt gcttcgtcgt gctgtcatgc atgggaaaaa attaggtatt
    26641 gaacaagcat tcttatatcg tttagtccct gttgttgggg aaatcatggt aagttattat
    26701 cctgaagtac ttcaacaaaa agaatttatt gaaaaagtta tccgtacaga agaagaacgt
    26761 ttcaatgaaa caatcaatga aggtttggaa atcttaaatc aagtgatcca agaagtaaaa
    26821 aacgaaaacg ggacgactct agcaggaaaa gacatcttca aactatacga cacatatggc
    26881 ttcccggtag aattaacgga agaggtggca gaagatgaag gactgaaagt tgatcatgct
    26941 ggttttgaaa aagaaatgga tgcacaacgc gaacgtgctc gctctgcccg cagtactgaa
    27001 aaatcaatgg gggtacaatc tgctttattg acagatatca aagtagaaag taaattcatt
    27061 ggatacacag aacaagaatc agatagtcaa ttattggtca tcgttaaagg tgagtctctt
    27121 ttgaatgaag tcgcagaagg tgaagctcaa atgatctttg atcaaacacc tttctatgca
    27181 gaaatgggtg ggcaagtagc ggatcaagga tggatcatga atgaagtagg cgaaatcgta
    27241 gcagttgtta cagatgttca aaaagcgcct aatggtcaat ttatgcacac cgtagaagta
    27301 aaagcaccaa tgagtgaagg acaaacctat catctattga tcgatcaatc gatgcgcaat
    27361 cggatcatca aaaaccatac agcaacccat ctactgcaca aggcattgaa agaagtactt
    27421 ggcgagcatg caaatcaagc tggttcttta gtcgctcctg gacatttacg attcgacttt
    27481 acccactttg gtcaaatcac ttcagatgaa ttagctgaaa tggaaagaat cgtcaacgaa
    27541 aaaatctggg aagctatccc agttgaaaca attgaaacag atatcgatac agccaaaaac
    27601 atgggtgcaa tggctttgtt tggtgaaaaa tacggacatg acgttcgagt agtaaatatt
    27661 ggcggctggt caatcgaact gtgcggaggc acacatgtag caaatacaga aaacatcgga
    27721 atcttcaaaa tcgtttctga atcaggaatt ggtgcaggcg tgcgacgaat cgaggctgta
    27781 acaagtaaag aagcgtacga actacttgaa gaagaagaaa aacaactaaa acaagtagca
    27841 acaattgtta aatcacctca attgaaagaa gttgtttcaa aagcggaaca attgcaacag
    27901 caagtaagag agctacaaaa ggaaaatgaa caattagcta gcaagttagc gaatcaacaa
    27961 gctggtgatg tattcaaaga tccagaaacg atcaatggaa aaacaatcat tgcagcacaa
    28021 gtaaaagtga aagatatgaa tcagctgcgt caattagctg accaatggaa acaaaaaaat
    28081 atttcagata ttcttgtttt agcaaacgaa caagaaggaa aagtcagtct gctagcggca
    28141 atgacgaaag aatcaaatga agctggacta aaagctggcg acttgattaa agcaatcgca
    28201 ccgaaagtag gcggtggcgg tggtggacgt ccagacatgg cacaagctgg cgggaaaaat
    28261 cctgctggta ttccagatgc acttaaagct gcgaaagaat gggttgcgca acaatagggc
    28321 gtttacgttt gacagaaaaa caaaagttca aacattgaac gaaacatgat tatgggggcg
    28381 aagacaaaca agtcttgccc tcatactttt ttcaattgga tggcgcatct aatcaaatgg
    28441 tcggattcgg atggtcttta gttgacgaaa gtgacagaaa tttttacgat tagtataaat
    28501 aaaaaggggt gaaaaaatga atagtagaaa taagaccttt cgactagtct tacgtgcgat
    28561 cttgttagca atcatcatcg tacaagcgat ggttccttgg ctggggttta ttccattagg
    28621 attcattagt ttaacaatta tccatatcac agtaattatt gctgcagtag tattaggccc
    28681 aaaagatggc atggtgattg gcttgttttg gggaatcgct acaattgttc gtgcctatgc
    28741 catgccaaca acgccatttg atacattagt gttcacgaat ccgattatct cggtagttcc
    28801 cagagtactt gttggcttag tagcaggctt ggttttccac tggatttatc aaaaaaataa
    28861 atcaataacg atcagctcag cctttgcagg ggtactgggt tcattggtca atacagtctt
    28921 agtgttagga ttcatgggat tattttatac aggtgcaacg gcagatgcct atggtgtaga
    28981 ctctgctctt ttatttaaaa ccttagcagg ggttgcagca atcaatggga taccagaagc
    29041 aataggtgcg ggaatcataa caccattact agcaaaagcg ttatttgcag caacaccgtt
    29101 gaaaccagaa taatgaccat cttttaatag taataggacg cacgatagat agaaaaagga
    29161 agagaggaga ggaaaacaat cgtcctctcc atctttttac ctgagcaaca agcaaactag
    29221 aaggggtaaa aaacttggct aagaaacaag aagaaaaaaa gaaacaaata ccgcaacagc
    29281 ggacaaaaaa aggagtacta gcgggtatct taggattggt tacgaatctg atcttgtttg
    29341 tctctaagct aatgatcggg cttttttcag gaagtgtctc cattatggct gatgcagtga
    29401 acagtctatc agatactgct tcatccatat tgactttgat cggatttaaa attgctgcaa
    29461 agccagcaga tcaggaacat ccttatggac acgaacgctt cgaatatatc agtgggttat
    29521 ttgtttcgat catcattact tatgtaggat ttcaattttt agagtcttct gctgaaaaaa
    29581 tcatccatcc agaaaatgtc tctttaacac ccatcgtctt ttttgtccta atcatttcca
    29641 tctttttgaa atttgcacaa ggcaaaatgt atcaggttat tgcgcaatcc attgattctg
    29701 aaacattgag agctacagca acagatagtt ataatgatgt ctttactaca ctggctgtat
    29761 tgctttcagc agcaatcgaa tgggtaactg gatggcgtat tgatggatat ataggttttg
    29821 ctttagcatt atatatcctt tatagtggat tgacgatgct tcgaaatttt gtatacgaac
    29881 tattaggaag tcgcccaacg ccagcagaga ttgaagaaat ggaagagcat ttaaatgctt
    29941 gcgatgatat acttggctat catgatttat tggtgcataa ctatggaccc aataaacgct
    30001 ttgcatcagt ccacatcgaa gtagatgaat caatgaattt gaatgtggct cataagatta
    30061 ttgatctgat agaaaaagac tttaaaaagt ctttggatgt ggaacttgtc tgtcacttgg
    30121 atccaatgcc tgttgataac gaaaaatact ataatatctt gcggcagtta aagcaaattc
    30181 ttcttgaaac aggtacaggg cttaatattc atgattttag agtaattcat caaggaaaaa
    30241 cgctgcaatt tgatgtagtg gtccctgaga aattccagtt tgttgataca gaactagaaa
    30301 gaatcttacg tagtcaaata gaagaaaaaa tcggagatta ccaattggaa attacgtttg
    30361 atcacaatta tcttttatat taaatgagaa actataaaaa gactccttaa agtttttaat
    30421 ttaaagagtc tttttttctt ttaattgttt atggagagcc tgacgtgcaa gattatctgc
    30481 tcctttattt ttgttttcgg gcaaccattg caggatcaat aaagaaaatt cggatagaag
    30541 ttcttggatt ctttgaaggt agggaaggaa gagctcgttc ttcgttgcgt ttttgtcgac
    30601 cgtagaaact agtgttttgc tgtctgaaaa acagaaaatc gtttcattct gtaagtcgtt
    30661 tttctttaga aattctaaag tttttaaaaa gacttcgaac tctgcttgat ggtttgtccc
    30721 tatagaaagc gggatagata gctgttcttg tttaccttga tagacaatca agattccacc
    30781 tccactagga ccagggttgc cttttgtaga ggcatcaatg tatactttta acataaaaag
    30841 agattctcct ttttgttcaa actaatgtta tggtaagatt atatcattac tgaatcggtg
    30901 agaggttaga gaatgaaaaa aaatattcga tggcagcctg aactggcaca tacgatcatc
    30961 tattggtcat tgaccttgat cattctgttt tttagtctga ttctttcttt agaaaacaca
    31021 ggtccttatt ggaaaagcaa ttttgtttta ggtatttttc ttgtttttct atttctaggt
    31081 ttgcggcgtt cttttatttt aaaatcaaac tctgtgatta tacgttatgc tgctttttgg
    31141 aaagaccgag aaatatctgt cggacagatt cgatctttga cgccaactaa tactggggtg
    31201 caaatgatgt tgcaagatga gaaagcccca tctgttttca tgatgcgaaa aaaagatcaa
    31261 gtagtccttt ttgatcattt tgaaaaaaac ggacccaaat cagaatcaat tccttatcct
    31321 tatacgaaaa aaagaaaaag ctaattttaa aaatcagaac ctaaaaaaac gaatttttac
    31381 aggaaaagaa aagagtgaga cgtacggttc atcccgttta gcgtctcact ctatttgttt
    31441 atctattcat gcatactagt atcggtagtc tgaacgttgc ctttcttgac atgggcagct
    31501 tgtgttcctc gattcccttc gatgatctca aattcgacca cttgattttc ttccaaagtt
    31561 ttgaatccct cttcttcaat cgcagtaaaa tgtacaaaaa tttcttctgt gtcatcataa
    31621 ctgataaagc cgtatccttt tttgttgtca aaccatttta caattcctgt ggtcaaagca
    31681 ctcacgacct ttctaaagtc tgatcatagc cttcattata aagagtattt ataagtacgt
    31741 caaataaatt aaaaacctgt aattttatgt tttttttctg aataaaaaaa ggtataattg
    31801 gcatatctta acaaagaaga tattttgttg aataaagttc gtgaaaaggg gtaatcaaat
    31861 gaagaatgat ctgcaaattt cacaagaaac agagctagaa ccgattgttg aagtggctag
    31921 taaattagat cttaaggaag acgatttgga actgtatggg aaatataagg cgaaaatcaa
    31981 tttttctgga atcaatcgat caaaggataa cgctgagggg catttgatct tagttacttc
    32041 catcaatcca acaccagctg gcgaaggaaa gtcaacgatc actgtagggt taggagacgc
    32101 gctcaataaa atcaataaaa aatctgttat tgcattgcga gaaccctcac ttggtcctgt
    32161 gatgggaatc aaaggtggtg ctgcaggcgg aggatatgca caggtattgc ctatggaaga
    32221 tatcaacttg cattttactg gtgacatgca tgctatcaca acagctaata atgcattatc
    32281 tgctctttta gataatcata ttcatcaagg aaatgaattg aacatcgatg cccgccgagt
    32341 gatttggaaa cgggtagtcg atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt
    32401 gggtgggcca atccaaggtg ttccaagaga agatgggttt gatatcacag ttgccagcga
    32461 aatcatggct atcttgtgtc ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag
    32521 gatcgttgtc ggctatacat ttgaccgtca gcctgtgact gctggagact tgaaagcaga
    32581 aggcgctctg gcattactgc tgaaagatgc aatcaagccg aatcttgtac aaacaattta
    32641 cggaacacca gcttttgtcc acgggggacc gtttgccaat atcgctcatg gctgcaatag
    32701 tattttagct accaagacag cattgagatt agcagattac gttgtcacag aggcaggatt
    32761 tggtgcagat cttggcggag agaaattttt agatatcaaa gtacctaact tgaaaaaagc
    32821 gccggatgct gtggtgattg tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa
    32881 aaaagatgaa cttaaaaatg agaatcttga tgctttgaaa gtaggttttg caaatttaaa
    32941 gcgccatata cgtaatatgg aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt
    33001 cgtaacagat acagacaatg aactcacact gttggagcac ttgtgtgaaa atcaggggat
    33061 tcttgccaag agagcgagtg tatgggcaga tggagcagaa ggcggcgttg atttagcaaa
    33121 agctgtagta cgattgattg atagaaaaga agctaattac aagccattat accgcctaga
    33181 agaaacgata caagaaaaga cagaaacaat cgtcaagaaa atttacggag gaaatggtgt
    33241 tgttttcagc aaaaaagcgc aaaaacaaat agaagagttt acgaagaatg gatgggacaa
    33301 actgccgatt tgtatggcaa aaacacagta ttcattttct gatgatcctt cactgctagg
    33361 tgcaccggaa gatttcacca tcacgatccg cgaaatcatc ccaaaattag gggcaggatt
    33421 tttagtagcc ttgactggag atgttatgac gatgcctggt ttgcctaaaa aacctgctgc
    33481 attgaatatg gacgtgacaa atgacggaga agtgttggga ttgttttaag cttgattata
    33541 atctaccatc gaaggagctg tattttgact acagcttctt tttttagacg atagggaatt
    33601 aattttgttt acactaggat cattcttttt ctttattgta ttttgagcta tactaaagca
    33661 taataggagg gtatgatgaa aacgacattt ataagaaaaa ccggttttta cggtatgggt
    33721 agctcgattc agctaagaat caacaatgaa aaacgcagtg ttctcagtca tgaacaaaag
    33781 ataacgcttg atctggaagt gccctttacg atgcaggtca ccttttattg gctaaaaagc
    33841 cccgtttata cagtgaaaga agcaaagcct gcttatgtga tcacaatgaa ttacttgatt
    33901 cttcaaatct atccgttttt atttctagca actgggttgg gggccgtttt cctacaaaat
    33961 ttatttttca gtttttttgc agttattgtg ttgattgcgt tctttttcta tataaaaaac
    34021 cgggcatatt tgatcaagga ggaaaattat ggcaaactct gatctttttt taatcagttt
    34081 caatcgaatc gaaaaatgga tgagagacga gatgggaaat gcacgaaata tgggatttac
    34141 cgaacttgtc agacgcctag ctcaaagaaa acaattaatg atcagaaaat acgaagatga
    34201 tcttttacag cttgctcagt taaggaatgc gatcgtccat gatcggatcg cagtcgattt
    34261 tgtcattgca gagccaaatg attggacagt caagcgaatc cagctgatcg aacaagaact
    34321 gattcagcct gaaaccgtgc tgcctcgatt tgcaaaacgt gtaacaggtt ttgaacaaga
    34381 tcttccgtta cttgaactgt taaagatagt agcagaaaaa aggtattcac aatttccgtt
    34441 atacaataaa ggaaaatttg tagcattgat tactttacgt aatatcgggt tttggctagc
    34501 aaaagaaagc caaaaaggtc cggttgattt aacaaataaa cgagcgttgg atttgatcat
    34561 ccaaaacgga aagtacacaa attatcattt tgttccagct aaaacacata tttacgaggt
    34621 tgaagcgatg tttcgtgagc aagggacttt ggaagccgta cttatcacta aagatgggaa
    34681 tcccgatggt aatctgctcg ggatcgtacg acctcgtgat atttataaac aaatagaaaa
    34741 ggattgattt tttgttaatt atttattgga tattcagcgc tttgctagta ggagtggatc
    34801 agttggtcaa atggtggatc actgataatc tagcgcttgg agagacgaaa aatcttatac
    34861 caggtatttt gtcactgaat catattcgaa acactggagc cgcatggagt atgctagaag
    34921 ggaagatgtg gttctttact atagtgacac tcattgcagt cgttgtgatt ctcacattga
    34981 tgattaaaaa tcgtgaaaaa ggtaatcgct ggttcatgat tggattgagt ttgattctag
    35041 ctggtgcgat tggcaatttt atcgaccgta ttcgtcttgg ctatgtagta gatatgttcc
    35101 agacagattt tatgagcttt ccgattttta acgtagcaga tgtgacactt gtatgtggag
    35161 tgatttgtat gttaatttat attattttag atgaaaagga tcaaagaaaa aaatgacaga
    35221 acttaaaacg acgattcacc atgaatctgg taggatcgat aaagtattga ctaatttatt
    35281 caccgattac agtcgttcgc aaattcagct gtggctgaaa aatggagcgg tttctgtcaa
    35341 tggacagcca gtcaaagcaa attacaaagt aaaacaagga gacgagatta ctgtcttgat
    35401 ccccgaacca gaaacattag atgtggtccc agaaaatatc ccgttgacga tcgtttacga
    35461 agatgaagat gtagcggtga taaacaaacc tcaaggaatg gtcgttcatc cttcagcagg
    35521 tcatacgcat ggcacaatgg tcaatgcgct gatgtaccat atcaaggatc tttctacgat
    35581 caacggcgtt attcgtccag gtattgttca ccgaatcgac aaagatactt ccggactgct
    35641 aatggttgcc aaaaatgacc aggcacacga atcattagct cagcaattaa aagataagac
    35701 ctctttgcgc aaatatgttg ctttagtcca tggagagatt cctcacgaaa aaggaaccat
    35761 caatgcgcca atcggccgtt cgaaggaaaa ccggaaaatg caggcgataa gagaagatgg
    35821 gaagtcggct gtcacacatt ttactgtatt ggaacgtttc gaaggattta ctctggttga
    35881 attaaaacta gaaaccggaa gaacacacca gatccgtgtg catatgaagt atatcggtta
    35941 tccgttagct ggagatccag tatacggacc gaagaaaact ttgaaaggca atggtcagtt
    36001 tctccatgcg caaatgttag gttttacgca cccgactaca aacgaaaaga tgatctttga
    36061 agcacctctt ccagaagttt ttgaaaaaac tttagaaaaa ttaagaaaaa acattgcatt
    36121 ttaatttaga taacggtata gtaattaaca acgaaagcat aaaacttaat agaattcctt
    36181 taagtttagt cccgtgaggc taagaagggt gggagcaagg atacgtatgg tgcgccataa
    36241 gtagattgct cattgacata gtatagctat cagtgtatca gtatacgctc agtctaaaca
    36301 ttcctcctgt cctcttaggg caggagtttt tttatgcaaa aaagtagggg gaatgaaaat
    36361 gcaagcaaaa gaagtagtag atcaggtaac catgaagcga gcattgactc gaattactta
    36421 tgagattatc gagagaaacc atagtatcca agatatcgta ttggtaggta tcaaaacacg
    36481 aggaatctac attgcatcaa gaattgccga acgcctgaag cagctagaag atatcgatat
    36541 tcctgtagga gaactggata tcactttata ccgagatgac aaaaaagaaa atccagaaga
    36601 accggaactt cattcttctg acatcccagt ttccttagaa ggaaaagaag ttattttgat
    36661 tgatgatgtt ttgtatacag gacgaacgat tcgagcagca atggacgcag taatggattt
    36721 tggcagacca agaaaaattt cattagcagt cctggtcgat cgtgggcatc gagaattgcc
    36781 aatccgtgca gattatgttg ggaagaacat tccaacatct cgggcggaag agattttagt
    36841 agagatgcaa gagcttgatg gacaagatcg catcatgatt ttgaaagagg aagattagag
    36901 gagagagaaa catgtcggag aaaaaaggat ttcataatga tgacgtggtg ttagatatcc
    36961 acgatcgccc aaccccagga cattgggtag gattaagttt acaacacttg ttcacgatgt
    37021 tcggagcaac cgtgttagtc cccatcttag taggtatcga tccaggtatt gcgctagtca
    37081 gttcaggact aggtacattg gtgtacttat ttactactaa aggaaagata cctgcgtact
    37141 taggaagcag cttcgctttc attgcagcga tgcagctttt gatgaaaaca gatggttatc
    37201 cagcgattgc acaaggagca gtcacaactg gattagtcta tttgattgtt gcgctgatca
    37261 tcaaaaagat cggttcagca tggctggata aaatcttgcc tccaatcgtc gtcggtccag
    37321 tcatcatggt tatcgggttg ggacttgcgg caaatgcagc aacaaatgct atgtataatc
    37381 agggcacgta tgatttcaag tatattgctg tagcgctgat cacattagga ttaacaattt
    37441 tcttcaacat gtggctaaga ggttttctcg gattgattcc gattttacta ggtattatta
    37501 gcggatacat cgtagccttg ctgtttggaa tcgtggatac taagccaatc gtagacgctg
    37561 cctggtttgc tgttcctaac tttgagattc cctttgtaca atatgaacca aagctatatc
    37621 ttggagcaat cacaacaatg gcacccatcg cttttgtgac gatgacagag catatcggcc
    37681 atcttatggt attgaataaa ctaactaaac gtaatttctt tgaagaaccg ggtcttcata
    37741 agacgttgac aggtgatgga ttagcacaaa tcgtggcagc ctttgtcgga ggtcctcctg
    37801 taacaagtta cggtgaaaac attggtgttc tggctatcac acgtgtccat agcgtgtttg
    37861 tgatcggtgg agctgcagta tttgcagtca ttttaggatt cgtaggaaaa ttaagcgctt
    37921 tgattttaag tatccctgga ccagtcatct caggaatcag ttttatctta tttggagtaa
    37981 ttgccgcaag tggaatgaag attttaatcg agaacaaaat cgattttgat aaaaagaaaa
    38041 atctgttgat tgcttcagtt atcttagtag taggaattgg cggactcgtc tttgaagtag
    38101 gcacatttac attgtcggca atggcattag caactgtact tggcatcatt ttaaatctta
    38161 tcttaccaga aacttcacga agcgaagaaa actaaggagg aaacattatg atcatcaaat
    38221 cagaacgtat cagcttaaag catttattga ccgttgaggc acttactgat caagaagtta
    38281 tgggcttgat ccgcagaggg caggaattca agcaaggtgc taattggact ccgcaaaagc
    38341 gccagtactt tgctacaaac ctctttttcg aaaatagtac tcgcacacat aaaagcttcg
    38401 atgtagcgga gaaaaaacta gggctagaag tgattgaatt tgaagcaagc acaagctctg
    38461 tccaaaaagg ggaaacacta tacgatacag tactgacgat gtcagcatta ggcgtagacg
    38521 tagcggttat ccgtcatggt gatgagaact attatgacga actgatacaa agtaaaacaa
    38581 tccagtgttc gattatcaat ggaggagacg gaagcggaca gcatccaacc caatgcttgc
    38641 ttgatttgat gaccatttat gaagaatttg gtcattttga aggtctgaaa gttgccatcg
    38701 taggtgatat cactcactct cgcgtagcta aatccaatat gcagatgtta aaacgtctag
    38761 gcgcacaagt attcttctca ggtcctagag aatggtacga cgatgaattc gaagtgtacg
    38821 gacattatat gccattggat gaactactag atcaagttga tgtcatgatg atgcttcggg
    38881 tgcaacacga acgccatgat ggaaaagaaa gtttctcaaa agaaggctac catcaggaac
    38941 atgggttaac agttgagcgt gcgaagaagt tgcaaaaaca tgcaatcatt atgcacccag
    39001 caccagttaa ccgtgatgta gaattagctg attcattagt ggaaggatta cagtcgcgga
    39061 tcgttcagca aatgagcaat ggagtattcg tcagaatggc aatcttagaa gcagtgctaa
    39121 atggaaaagc gtaattatag gaggatgaaa aaatgaaaac actcattaaa aacggtcaga
    39181 tcaatacacg aaaaaatatg acgacaccag cagaaatttg gatagaagat gggcgaatca
    39241 aagcaatcgg tacaggattc tcagaagccg aatttgatga agtgtttgat gcaaagggac
    39301 aattgatcac acctggttta gtggacgtcc atgttcattt gagagagcca ggatttacat
    39361 acaaggagac gatcgaagct gggactcgct cagctgctcg tggcggtttc actactgtat
    39421 gcgcgatgcc gaatttaaat cctgtacctg atacggcaga aaagctgaga caagtatatg
    39481 acatcattag aaaagatgca gttgtgaagg tattgcagta tgcgccaatc acagaaaatc
    39541 tgcgaagtga gaaattagtt gatcaagaag cactgattga agaaggtgct tttgctttca
    39601 caaatgacgg tgtaggtgtc caaacagctg ggacgatgta tctggctatg aaagaagctg
    39661 caaaaaacaa taaagcccta gtagcccata cagaagatga atctttatta tttggcggcg
    39721 ttatgcacgc tggcaagaag gcagaagaac ttggtcttcc cgggatctta agcgtaaccg
    39781 agtcttctca aattgctaga gatctgttgc tagctgaagc aactggtgtt cattaccatg
    39841 tttgccatgt ttctactaaa gaaagtgtcc gtgtaatcag agacgcaaaa aaagcaggaa
    39901 tccacgtaac agcagaagtt tcaccccatc atcttatttt gatcgacgaa gatattcccg
    39961 aagatttcgg cttttggaaa atgaacccgc cgctaagagg acgggaggac agagaagctt
    40021 tgatcgaagg cttgcttgac ggtacgatcg attgcatcgc tacagaccat gccccccatg
    40081 gattagaaga aaaaagccaa agtttcatga aatcaccatt tggtatcgta ggaagcgaaa
    40141 cagcgtttca actgatctat actcattttg tagaaactgg tcgattcacg ttggaacaag
    40201 tgatcaattg gttggcagtt aaaccggctg agatttttgg tttgaatgca ggaacgctaa
    40261 cggttggtgc ccccgctgat gtagcagttt ttgatattac acaaacttgc acgatcgata
    40321 aagaagactt tttatcaaaa ggggagaata caccttttat cggctggaaa gtaaaaggcg
    40381 aaacacaaat gacttttgtc aacggaaaac ttgtgtggca gaagggagaa taaaagtatg
    40441 gaacgtttgc ttatattaga agatggaaca gttttcgaag gaaaggcttt tggtgcagat
    40501 gctagtgtct tcggagaaat cgtttttaca acaagtatga ctggttatca agaaactatc
    40561 actgatcaaa gttttaacgg tcaaatcatt acatttacct atcctatggt gggtaattat
    40621 ggggtaaata gagatgatta tgaatcgatt tctccaacat gcaaaggagt agtagtaaaa
    40681 gaacatgcac gtgtagcttc aaactggcga aaccaaatga cgctagattc atttttgaaa
    40741 caaaaaggaa ttcctggaat atcaggtatc gatacgcgcg cccttactcg caaaatccgt
    40801 gaagtcggaa cgatgaaagc tagtatagtt gatgctggag attccttcga acatgcattt
    40861 gatcagctga aagcaaccgt tctagcaacc aatcaagtgc agcaagtctc aactaacaaa
    40921 ccttatccaa gtccaggaac aggtcggaaa gtcattgtca ttgacttcgg cttgaaacat
    40981 agtattttac gagaattgag taaaagaaac tgtaacctca cagtacttcc ctataacaca
    41041 gatgccgaga cgattttagc gctatcacca gacggagtca tgctgacgaa tggacctggt
    41101 gatccaaaag atgtgccaga agcaatcgaa atgatcaaaa aaatccaagg aaaagtaccg
    41161 atttttggta tttgtctcgg tcaccagtta tttgctttag ccaacggtgc agatacctat
    41221 aaaatgaaat tcggacatcg aggattaaat cacccggtac gagaagtagc gaccggaaga
    41281 attgatttta cttctcaaaa tcatggctat gcagtcgatg aagccacgat tgatccagaa
    41341 aaactcatcg taactcatgt agaagtaaat gacggaacag tagaaggagt caaacacaga
    41401 gattatcccg ctttcagtgt gcagtttcat ccagatgctg cccctggtcc gcatgatgca
    41461 ctacatttat ttgatgaatt tatggaaatg atggacgcag gaaaggagca gtaaacagat
    41521 gccgaaacgt acagatatca agaaaattat ggtgattgga tctggtccga tcatcattgg
    41581 tcaagccgca gaatttgact acgcaggaac acaagcctgc cttgccttaa aagaagaagg
    41641 atatgaagtg gttttagtaa attctaatcc tgcgacgatc atgacggata aagaagtggc
    41701 agatcaagta tatatcgaac cgatcacact tgaatttgta tcaaggattc ttcgaaaaga
    41761 gcgtccagat gctctccttc caactttagg cggacagaca ggcctcaata tggcaatgga
    41821 gctggcagca tcaggtattt tagaagaatt gaacatagaa cttctaggaa caaagctttc
    41881 tgcgatcgat caagcagaag atcgtgatct attcaaacag ttgatgaaag aattgaatca
    41941 gccaatcccc gagtctgaaa tcgtcaatac agtagaagaa gctgtagatt ttgcaaataa
    42001 aatcggctat cctgtcatcg ttcgtccagc ctttacttta ggcggaactg gtggaggtat
    42061 gtgtgaaaat gaagaagaat tacgtatcgt atcagaaaat ggattaagtc tttcccccgc
    42121 tacccaatgt ttgattgaac gaagtattgc aggttttaaa gaaattgaat atgaagtgat
    42181 gagagattcg gctgataatg caatcgttgt ctgcaatatg gaaaattttg acccggtggg
    42241 tatccataca ggtgattcta tcgtatttgc ccctagtcaa acattgtctg accatgaata
    42301 tcaaatgctt cgtgatgctt ctctttcgat tattcgagca cttaagatcg agggaggctg
    42361 taatgtccaa ctcgctcttg atccacatag ttttaattat tatgtgattg aagtcaatcc
    42421 gcgtgtttct cgttcatctg cgttagcaag taaggcgact ggctatccga tcgctaagct
    42481 agctgctaaa atagcgcttg gattaacatt agacgaaatg aaaaatcctg ttacaggaac
    42541 gacttttgca gaatttgaac ctgcattaga ttatgttgta gctaaaattc ctcgctggcc
    42601 gtttgataag tttgaaaacg gagaacggct tttaggcacg cagatgaaag caactggtga
    42661 agtgatggct atcggtcgga atatcgaaga gtctttattg aaagctgtgc gttctttaga
    42721 aatcggtaca caccatatcg aacttcctga gttggcagac atcacggacg atgacctaat
    42781 ccaaaaagtg gttcgagcac aagatgatcg cctgttttat gtagctgaag ctattagaag
    42841 agggtacacc atagaagaat tagcggattt gacaaaaatc gatttattct ttttagataa
    42901 actgttgcat atcgtagaaa tcgaacagca gttgaaacag cagccgttgg atgacaagat
    42961 attgaaaaca gcgaaacaaa acggttttac agacaaaaaa gtggcggagc tgtgggaaat
    43021 aaacgaagaa gccgttcgcc agatgagaaa agaaaatgat ttgattcctg tatataagat
    43081 ggttgacact tgtgcagcgg aattcgaatc aaaaacacct tatttttata gttcctatga
    43141 atatgaaaat gaaagttcac gatcagaaaa gccctcaatt ctagtactgg gatctggtcc
    43201 tatccgtatc ggacaagggg ttgaatttga ctatgcgact gtgcattctg tcaaagcaat
    43261 ccagcaggca ggatacgaag caatcatcat gaacagcaat cctgaaacag tttcgactga
    43321 cttttctatt tcggataaat tatattttga gccattgacc ttcgaagatg tgatgaatgt
    43381 gatcgagcta gaacagccga taggagtaat cgttcaattt ggtggtcaga cagcaatcaa
    43441 cttagccgaa cctttgactg ctgctggtgt aaaaatctta gggacaacga tcgaagactt
    43501 ggatcgtgcg gaaaatcgtg atttattcga gcaagcgctg aaagagttgg atattcctca
    43561 acctttaggg gatactgcta caagtaaaga agaagccgtg gttatcgctt cgagaattgg
    43621 ttatccagtt cttgttcgtc caagctatgt attaggcgga cgtgcgatgg aaatcgttga
    43681 aaaccagcga gatttagaag attacatgga acatgctgtg aaagcatctc cagaacatcc
    43741 agtactagtg gaccgttact tgcttggtgg tgaatgcgaa gtggatgcga tttgtgacgg
    43801 tgaaacagta ctcatcccag ggatcatgga gcatattgag cgtgctggtg tccattcagg
    43861 ggattcaatg gctgtgtatc cacctcaaac attatctgaa tcgatcaaga aaacgatcga
    43921 agattacacg atccgcttag cattaggttt gaattgtgtc gggatgatga atatccagtt
    43981 tgtcatccat gaaaatgagg tttatgtgat cgaagtcaat cctcgagcaa gtcggactgt
    44041 tccattctta agtaaggtga caggaattcc aatggcacaa attgcgacga aagctatttt
    44101 gggagagaaa ctaaagacac ttggttatga aaacggactt tatccagaaa caaaagaagt
    44161 tcatgttaaa gcacctgtct tttcttttac gaaattgcag aaagttgata cttacttagg
    44221 gcctgaaatg aaatcgactg gagaagtaat gggatctgac agacaattag acaaagcttt
    44281 gtacaaggca ttcgaagctt ctggattaca cttgcctgaa tatggagccg tattatttac
    44341 gattgcggac gaaacaaaag aagaagcact agaattagct aaacgtttta cagaaattgg
    44401 ctatagtctg ataggaacga aacatacagc tgcttatttc gaaaaaaatg gtctggtcgt
    44461 tgaaacagta gcgaaaattt ctgaggaagc agcagaaaaa aatgtagtcg acttaataag
    44521 agatggtaaa acacaagtgg ttgtcaatac gattgataaa gatcggggaa atgcttctaa
    44581 agacggtttc atcatccgaa gagaagcagt tgaacatggt attccattgt ttacttcttt
    44641 agacacagca gatgcgatcg ttcgagtgat ggaatcccgt gctttttcaa ctaaccctat
    44701 ttaacggcga gcacatgtta agacaaaaag acgaaaaacc gttgcaggag gggacagatg
    44761 aaacaagaaa tgatggaaat cgttcagcaa aaacagctgg caccaaagat ttttgaaatg
    44821 acattgaaag gtgatctagt aaaagaaatg cagcaaccag gacagttctt gcatattctc
    44881 gtgccgcgtg cagacttgct attacgccga ccgattagct tgaatcatat cgaccacgaa
    44941 acaaatactt gccgtatcat ttatcgggtg gaaggtgagg ggactagagt cttctctact
    45001 ctttctgccg gagaccattt agatgtcatg ggtcctttag gcaatggttt tgatttgtcc
    45061 aatcttcata caggagacga agtatttata atcggtggag gaatcggtgt ccctcctcta
    45121 tatgagttat caaaacagtt agtcgaaaaa ggaattaagc caacgcattt tttaggtttt
    45181 gccacacatg aagtcgttta ttatgaaaaa gaatttaatc gtctaggaga aacaagaatc
    45241 gctactgacg atggaacata cggtatgcac ggaaatgtcg gtaatttatt gttaggaacg
    45301 aagacggaac ctacagctgt ttttgcatgt ggttcaaacg ggttattgaa gacagtggaa
    45361 cagctgtttt cttcgcatca aaatgtccag ttatcattag aatcccgcat ggcatgtggg
    45421 ataggggctt gctatgcttg cgtttgtcat acgccggaag atgaaacagg aacaaaaagt
    45481 gtgaaagttt gtgacgaagg accgattttt aaaataggag aggtaattat atgaatgaga
    45541 atcctttagc ggtcaaactt cctggcctag aattaaaaaa tcctatcatg ccggcaagcg
    45601 gctgtttcgg ttttggcaaa gaatacggaa aatactatga tttgaatcag cttggatcga
    45661 tcatggtcaa ggcaacgact ccaaatgccc gctttggcaa tcccacgcca agagtggcgg
    45721 aaacaccatc tggcatgttg aatgcaattg gtttgcaaaa tcctggtcta gacgttgtta
    45781 tgcataaact tcttccagaa ttagaggagt acaatgagtt acccatcatc gcaaatgttg
    45841 ctggtgcttg tgaagaagac tatgtagaag tttgtagcaa aattggcgaa gcaccaaatg
    45901 tgaaagcaat cgagctgaac atttcttgcc caaatgtcaa acatggcgga attgcttttg
    45961 gaacagattc tgatgttgct tttcaattaa cacaagcagt aaagaaagtt tcttctgttc
    46021 ctgtctatgt caaattgtcc ccaaatgtaa cagacatcgt tccaatcgct caggcaatcg
    46081 aagctggagg ggcagatggg tttacgatga tcaatactct tcttggtatg cggattgacc
    46141 ttaagacaag aaaaccgatt ttagccaatc aaacaggtgg actctccgga ccagcaatca
    46201 agcctgtcgc tattcgtttg attcaccaag tagcaagtat atccagcctt ccaatcattg
    46261 ggatgggcgg cgtgcagaca gtggatgatg ttcttgagat gtttatggct ggagcaagtg
    46321 ctgtagctat agggaccgcg aatttcaccg atccgtatat ctgtcctaaa ctaattaaag
    46381 agctccctgt gcgaatgagc gaactaggca tcgaatcgct ggaaagatta atcaaagaag
    46441 tgagagagga acgtgaacga tgaatcaact agaccaacga ccaattattg cattagattt
    46501 ttcaactagg caagaggtag aagactttct tcgatttttc ccgaaagaag aaaaattgtt
    46561 tgtgaaaatc ggaatggaat tgttctacca agaaggacct gaaatcgtac gttatctaaa
    46621 agaggctggt cataatgtat ttttagatct gaaacttcac gatattccga atacggtcga
    46681 aaaagcaatg cggggattgg caaagcttgg tgttgatctc acctgtgttc atgccgctgg
    46741 cggtattcgt atgatggagg cggcaatgcg aggattagaa gaggggactc cagaaggtgg
    46801 aaaacgtccg ctacttctag ctatcactca gcttacttct acaagtgaag aagaaatgca
    46861 tgccgatcaa ctaatcgaag tttctttaga aaaaagtgtg atccattatg ctagctgtgc
    46921 caaaaaagca ggattagatg gtgtggtttc ttctgcttgg gaagtagaag cgatcaaaga
    46981 aatggcagga gacgaatttg tttgcttaac tccgggtata agaccagaag gaacagtcgc
    47041 aggagatcag acaagagtag tcacaccttc tcaggcaaaa aagatcggct caacttttat
    47101 cgttataggt cgaccaatca ctcagtcaac taatccttat aaagcatatc aaacgattca
    47161 aacagaatgg agctaaccta aaatgaatgt tgaacaaagt atcgcaaaag acttattaga
    47221 aattgaagca gtatttttaa atccaagtaa tccttttaca tgggcaagtg gaatcaaaag
    47281 cccaatttac tgtgataacc gaatcacgat gagctatcca aaagtccgaa aagagatcgc
    47341 aaaaggatta gcaagcaaaa tcaaagaagc ttaccctgaa gtacaagtga ttgctggaac
    47401 tgcaacagca ggaatccctc atgccgcatg ggtagcggaa atactggatt tgccaatggt
    47461 ctatattcga agtaaggcga aagatcatgg gaaaggtaac caaatcgaag gacgtatatt
    47521 tgaaggtcag aagatggttg tgatcgagga tttgatttct acaggcggaa gtgtcttgga
    47581 agcagctgaa gcagcaaaaa gagaaggtgc ggatatcctt ggtgttgcgg ctatctttac
    47641 gtatgagttg ccaaaaggaa aagcaaattt cgaaaaagcc gaaatccctc ttatgacgtt
    47701 gaccaattat tctgtattga ttgaagcagc tttagaagat cgttatatcg atgagcaaga
    47761 attaactctg ctaaaagaat ggaaaaaaga tcctgaaaat tggcagattt aagcgcgctt
    47821 gatgaagata gagaaatccg atttgtgtct ccagaatcat caattggaat agcaaaaatc
    47881 caaaaactga ttgcgagaag catcttttca tcaggtatga aaagaaactt ctatcgtgat
    47941 cagtttttga tttttttaaa attcattttt ctaagactgg ttagcagaaa gaagagaata
    48001 atctcttctc ttttttctat tatatataga ttttctctat tttttggtaa gggagctgtt
    48061 tcaaaaatgg taaagagcgg aaatgttgcg aatatcagtt atttaatgat atgatattcg
    48121 gaaaaagaaa tctcaaaggg aggtaacttt tatggggttg aatgaattta ttttaggatt
    48181 gaacaattta gagacgatca caagggcacc tggatttttt aaatatacag agcatacagt
    48241 tgcagcacat tcgtatcgtg tagcatctat tgcgcaagtt ctaggagaca ttgaagaagc
    48301 gaatggacaa ccgatcgatt ggaaactgct ctatgaaaaa tcattgaatc atgactacac
    48361 agagcgtttt attggtgata tcaaaacgcc ggtgaaatac gcaagcaaag agttaagagg
    48421 gatgctgcaa acagttgaag aaaagatgac ggacgaattc atcaaccaag agattccagc
    48481 tgagttccaa gaagtttatc gccgtcggtt gttcgaagga aaagatgaaa ccgtagaagg
    48541 agaactatta gccatttcag ataaggttga ccttctttat gaatcttttg atgaaatcat
    48601 caaaaataac ccggaaaaag tttataagga gatgttcatt gaggcagtga ctacgattaa
    48661 aagctttgaa catcggcctt ctgttcagta tttctttaaa gagatatttc cggaactatt
    48721 gaaccaggaa ttttatggaa aagaggcgtt tttagaaacc gtctcaacga ttgtaaagaa
    48781 agaagaaaaa taaaaatgat atgagatgca gggggaagta tagttgaaaa agaatatgga
    48841 tgtcgaatgg ggctattctg gagacaaagg tccggaaaat tgggcgagtt tatgtgattg
    48901 gtttgcgaga ggtgcggaat ttccattgca gtcgcctatt catttgacca agggggaaga
    48961 aaccaaaata gaaggagaca cgctttcctt tcattatcaa aagcaacggt ttactgacaa
    49021 ggaattcaaa aacacgattc atttagtacc ttttgaccaa ctcagttatg tagagttcaa
    49081 gaaagaacgc tattatttga cagatattca tttccacttg ccttctgaac atatcatcaa
    49141 cggaaaacag gaagatattg aatttcattt tgttcatatg aacagcaaaa aagagaatct
    49201 agttgtgggt gtcatgtacc agctaatggt acaggaaggt tggctgtata atcaagaaaa
    49261 tggggaaagt tggaacttag aaaaacatga gcattgggta aatccggatg tgttctttcc
    49321 ggagcaaaaa agccatttcc attatattgg ctcattgaca actccgccta ccagcgggcc
    49381 aatccaatgg tttgtaatgg atcatgtagg aaaactgaac caagagtttc ttctcccctt
    49441 cgatggtcag tatgctcgac cgaacaaccg accaatccag cccttgaatg gaagagaaat
    49501 ttattatttc gaggagtttg agcaatgaat attcagcaga tgaaatacgt ggtcgctgta
    49561 gcaaacaatg gtagtttcag agaagcggca aagaaaatgt ttgtctccca gccaagtctt
    49621 tcagctggta tcaaagaatt agaaaccgag ttagggatca cgctgtttac tcgaacgaat
    49681 cgaggggcat atttaacaga agaagggcaa gacttcttaa atcgtgccga gaaaatattg
    49741 gtccagcttg atacattaga aactcactat ctaacgagtg aaaagagaga caatttttcg
    49801 atcgctgccc agcattatga tttcttaggt cctttgaccg cacagctact cgaggaattc
    49861 aaagacgaga tcaaacaatt tcggatcatg gagacgacaa cagcgagagt gatcgaagaa
    49921 gtcaaagagc agcacagtga gatcggcatt atttatatga atgagcataa tcaagctggt
    49981 atcagaagat atttacaaca aggagagcta agtggccgca gcattggaaa attcaaaacg
    50041 catatttttt taaggcaagg acatccatta gctgaacacg cagagatcac caaagaagaa
    50101 ttgttatctt atcctcaagt tcgttttaca caggatggaa ataatttccc gtatttttat
    50161 gaagacctta tcgagatccc tgatcaagaa acagtgattt atacgagtga tcgaggtact
    50221 ttgatgaata tcgttcttga aactgatgct tacgcttcag gatctggtat tgtgattgga
    50281 gggattcgcg agcacttgcg gttaatccct ttggcagaag gcgaactaaa tgaattttat
    50341 atcatttatt cggcgaaacg tccgctcagt gaaatcgctc aaagatttat caaagagctt
    50401 actcggttac tggaccagca gagctaagaa aagcagatga gaacgctgtt tattgaacac
    50461 cgttgatcaa aaaagagggg ttgtgacaga attttgtcac aactcctctt tttgtagcaa
    50521 acaatttata actaattgct gttgtgggaa agtacgcaaa tatgattcta gaaacactca
    50581 ttgattacct gttttgtttc atagctgtaa ttttttcttc ttctggtgtc acgataatcg
    50641 tcttttggtt ttcataaata acataaccag gcttggcgcc atttggtttt cggatatgct
    50701 ttacctgtac aagatcaacc ggcacttggg cagagtatcg gtattttgaa aaataggcag
    50761 ctaactcggc agcttctgta attgtttcat ctgagggctt gtcactttta atgatgacgt
    50821 gcgaaccggg tatatttttt gcatgaagcc aatagtcggt ttttttagct gtcttcattg
    50881 tcagctggtc attttgaaga ttgtttttac caacaagaat gagcgttccg tcagaagaaa
    50941 agtattgatc aggctgagat ggtttcttac gtttttgttt ttttaagttc ttctttttca
    51001 ggtatccttc tgaagtcaat tcttctttaa ttgcttcgat atccattggg ccggcaattt
    51061 ccagttgaga taagacagat tcaagatatt ggatttcatc tttggcttct tggatttgtt
    51121 cgccaatcag cttaacagcg ttcttcagct tttggtatcg atggaaatat ttctgtgcat
    51181 tttgatttgg tgtcaatgcc ggatctagtg ctattttgat tggccgatct tcttcataat
    51241 aattaggtaa aacaacttct tttgcgccgc gtggtacttg tgtcagaaaa gtagtaagta
    51301 gttcgccatt tctacggtaa ttctcagcgt tttcggattc tttgagtgtt tgttcacgtt
    51361 ttttcaattt atttttattt cgttttagtt cattttcgat ttttcgaatc agttctccgc
    51421 cttgttgttt tgcccgatct ttctctgctt tttcgtgata atagctatct aataattgac
    51481 tgagtgttgg ataagctgtt acagcagatg cctgttcgga caatacctga taagcaatcg
    51541 gtgtgaaaaa atctttattt tccgtttcgt aaaaagtagg aataggctga tggctgatgg
    51601 ctgagaaaaa ttcgtcccat acaaccatct tttcattagg acgttccagt aatcttttgg
    51661 tcagctcttg agcgatatcg aaaccgattc cctgaaactg acgttggatt gcttttggat
    51721 ctagttcagt ttgggaaagc cgctgaaaga ttttttcttt ctcggagcta aatgggttca
    51781 agacctcttg ttttggcgga gcaacatatt ctacaccagg aagcaaagaa cgataagtgt
    51841 tttgagagct tccaatgtgt ttgatcgcat ccagtatttt tccagtttct cgattaacta
    51901 agacgatcgt actatgacgt cccattaatt caacgatcaa tatgatattt tgtagatcac
    51961 ccaactcgtt tcgtttagca aagtggaaat ggatcactcg atcattttcg atttgttcga
    52021 tgtcttctaa aatagcgcca tccaaatatt ttcgaagcat catcacgaag ttaggcggat
    52081 tatcaggatt ctgataatcg atttgggtaa tctgtacacg agcataactt gggtgcgcag
    52141 ataataataa tcgatggttt ttgccgcgtg aacgaatcac cagcacgatt tcattttcat
    52201 aaggctgatg gattttcgag atccggccag atagtaacgt ttcacgcaat tcgttgacca
    52261 tcgcgtgggt aaatacacca tcaaaggaca tggttcattc ctcatttctt ttcataagta
    52321 tattcattat aacgaaaaaa agaagaaaaa ccaatttggc cgaatagtaa agcaaaagtc
    52381 tagaaaaatc ttggactaat tacataaaaa acagtgtttc tatcgttgaa atccaaattt
    52441 ttaggt
//
LOCUS       DAPBBV010000020        49117 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.020, whole genome shotgun sequence.
ACCESSION   DAPBBV010000020 DAPBBV010000000
VERSION     DAPBBV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 49117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49117
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.020"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            598..1287
                     /locus_tag="RD486_001401"
     CDS             598..1287
                     /locus_tag="RD486_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7663136.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="RD486_001402"
     CDS             1274..2482
                     /locus_tag="RD486_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7663137.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="RD486_001403"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="RD486_001403"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDT7663138.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="RD486_001404"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="RD486_001404"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDT7663139.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="RD486_001405"
     CDS             complement(6585..7280)
                     /locus_tag="RD486_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HDT7663140.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="RD486_001406"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="RD486_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDT7663141.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="RD486_001407"
     CDS             complement(8479..8670)
                     /locus_tag="RD486_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDT7663142.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="RD486_001408"
     CDS             complement(8691..9581)
                     /locus_tag="RD486_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDT7663143.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="RD486_001409"
     CDS             complement(9568..10335)
                     /locus_tag="RD486_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7663144.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="RD486_001410"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="RD486_001410"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDT7663145.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="RD486_001411"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="RD486_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDT7663146.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="RD486_001412"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="RD486_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDT7663147.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="RD486_001413"
     CDS             14906..15289
                     /locus_tag="RD486_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663148.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="RD486_001414"
     CDS             complement(15457..16215)
                     /locus_tag="RD486_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HDT7663149.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="RD486_001415"
     CDS             complement(16233..17051)
                     /locus_tag="RD486_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDT7663150.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="RD486_001416"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="RD486_001416"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDT7663151.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="RD486_001417"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="RD486_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDT7663152.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="RD486_001418"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="RD486_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDT7663153.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="RD486_001419"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="RD486_001419"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDT7663154.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="RD486_001420"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="RD486_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDT7663155.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="RD486_001421"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="RD486_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDT7663156.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="RD486_001422"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="RD486_001422"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDT7663157.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="RD486_001423"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="RD486_001423"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDT7663158.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27093..27392
                     /locus_tag="RD486_001424"
     CDS             27093..27392
                     /locus_tag="RD486_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDT7663159.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="RD486_001425"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="RD486_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7663160.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /locus_tag="RD486_001426"
     CDS             27980..28216
                     /locus_tag="RD486_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDT7663161.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="RD486_001427"
     CDS             28359..30332
                     /locus_tag="RD486_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDT7663162.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="RD486_001428"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="RD486_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDT7663163.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="RD486_001429"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="RD486_001429"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDT7663164.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="RD486_001430"
     CDS             33211..34503
                     /locus_tag="RD486_001430"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDT7663165.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35290..36153
                     /locus_tag="RD486_001431"
     CDS             35290..36153
                     /locus_tag="RD486_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7663166.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36282..37904)
                     /locus_tag="RD486_001432"
     CDS             complement(36282..37904)
                     /locus_tag="RD486_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7663167.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38153..38674
                     /locus_tag="RD486_001433"
     CDS             38153..38674
                     /locus_tag="RD486_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDT7663168.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38860..40590)
                     /gene="spxB"
                     /locus_tag="RD486_001434"
     CDS             complement(38860..40590)
                     /gene="spxB"
                     /locus_tag="RD486_001434"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HDT7663169.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40755..41573
                     /locus_tag="RD486_001435"
     CDS             40755..41573
                     /locus_tag="RD486_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDT7663170.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41676..41873)
                     /locus_tag="RD486_001436"
     CDS             complement(41676..41873)
                     /locus_tag="RD486_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663171.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42042..42620
                     /locus_tag="RD486_001437"
     CDS             42042..42620
                     /locus_tag="RD486_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDT7663172.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42715..42852
                     /locus_tag="RD486_001438"
     CDS             42715..42852
                     /locus_tag="RD486_001438"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663173.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43665..44168)
                     /locus_tag="RD486_001439"
     CDS             complement(43665..44168)
                     /locus_tag="RD486_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7663174.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44527..45552
                     /locus_tag="RD486_001440"
     CDS             44527..45552
                     /locus_tag="RD486_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7663175.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45875..46753
                     /locus_tag="RD486_001441"
     CDS             45875..46753
                     /locus_tag="RD486_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HDT7663176.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47229..47345
                     /locus_tag="RD486_001442"
     CDS             47229..47345
                     /locus_tag="RD486_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDT7663177.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48273..48611
                     /locus_tag="RD486_001443"
     CDS             48273..48611
                     /locus_tag="RD486_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663178.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48705..48935
                     /locus_tag="RD486_001444"
     CDS             48705..48935
                     /locus_tag="RD486_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663179.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
BASE COUNT        15145 a         9157 c         9611 g        15204 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtgt attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagatcag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg taaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggatcaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggtggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccggcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agacattgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg gggaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatccgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaatccttga
    25441 aaactatatc gaacatcaac gcgaagtcat cacacgacgg acggtctttg aaaaagaaaa
    25501 agcagaagca agagcacaca tcttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgag gcaaaagcaa caatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gtacagccaa aggaatccca atcatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg tcagagggat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaaa atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttgaagaac aaggatcaga agaataacca tcaagactaa gtgtgtaagc
    26881 tagcaagaat aaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taattagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tagatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaatgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata ttgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga accgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaagaggtag tgaaagagac gtttagcctt attgccgata
    34621 ggctgtctct tgaacactgt ttattcagaa taagggactg tgacaaaaac cgtgtcacag
    34681 tccctttttc cgaacaaacg gtgttcaaaa gcttgcatct acggcactaa gcccaatcag
    34741 atgaaaaata tggagtgcta tttttatctg attgttctta ctgcttgatg cagagcagct
    34801 ttttcacaac ctctccacta aacggtgttc tcctgccaac tcctcggtca caagtcacaa
    34861 tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg gagctaaacg
    34921 gcaggctcac aacctcttgg taaacggtgt tcaatcagct gaccctcggt attagctcaa
    34981 aaaacggcaa aatatgagga actatttttt ccgttttttt ctctaatact caggtcaaaa
    35041 cgctgatttc acaacctctg attcacggtg ttccagaagt agcttctacg gaaataagcc
    35101 gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt cttgaagctg
    35161 accacttctg tcacaacctc ttattttgat tagaacttgc gaaaataaac cggttaaagt
    35221 gtgtctagcg caagagattt gctataatag acgataaggg taaaatgtaa cgagaagggg
    35281 ttgaaaaatg tgtatcaaat tgtaacagat tcttgttgtg atctgccata ccatgtatta
    35341 gcaaaagaaa aagttgattt tttatcaatg aatctccaat tgaatgatca agagttagta
    35401 gatgacctcg gaaagacatt caattatgac cgctacatga atcagctgaa aaatggtgcg
    35461 atgcctacga catcacaaat caatgttggc cgatatttag aatttttccg ttcttatgcg
    35521 gaaaaacaga ttcctgtttt atatgtggct ttttccagtg gattaagcgg ctcttacagt
    35581 agtgcgcttc aagcggttga attgctgaag gaagaatatg aagaccctga gatctatgtt
    35641 tttgatacaa aagctgcaag tattggggaa gggcttttag tattggaagc tgtaagattg
    35701 aaaaaagaag gtaaaagcat cgaagaaacc ctagagtggc tggaaagtaa ttatttgaaa
    35761 gtccattcat gggtaacagt agacgatctg aaatatctag aacgaggcgg taggatttcc
    35821 aaagcaagtg ctactcttgg cagtctattg agtgtaaagc ctattattac ggtggataaa
    35881 gaaggaaggc tgacgaatgt tgacaaagtt cgaggaagaa acaagtcgat ccagacaatc
    35941 gtcaatgaga cggtaaaaac aatcgttgca ccacttgatc aaatcgttta tgtggcttac
    36001 gctggggatc tagagagcgc ggagaaggca aaacggcttt tggaagagca gataaagatg
    36061 aaagatgtga agctttatcc cttaggacca acgatcgcca gtcacacagg ctatggctgt
    36121 atcgcgattt tttcgatggg aatcagtcga taaaagcagt aactcattct gtaaaaaagc
    36181 ccagaaattg attgtaacaa aaacagcgac tcttaaaaga tagatgagca tcctatctct
    36241 tagaggtcgc tgttttttta ttttttaagc taaataggcc attatgccca taactcgttc
    36301 aattgttttt gaatatctgc attttccaaa aattcatcat atgtcgtatc agctcgatcg
    36361 atcacacctt tatccgaaac ggcaatgatg cggtttgcca atgtttggat aaattgatgg
    36421 tcatgtgacg caaataagat tgagccagta aatgccatca agccgtcatt caatgctgtg
    36481 attgattcta agtctaaatg gttcgttgga tcatctaata caagtacgtt agctttcgaa
    36541 agcatcattt ttgaaagcat gcaacggact ttctctccac cagataaaac attcactggt
    36601 ttcaatactt cttcaccaga aaacaacatt cttcctaaga agcttcttaa gaaggtgtta
    36661 tcatcttctt ctttacttgc atattgacgc aaccagtcta aaatcgttag atcagtatcg
    36721 aattctttcg ttgtatcctt tggtaaataa gaattacttg ttgtcacacc ccaacgtact
    36781 gttccagtat ctggcgtaat ttcacccatg ataactttga atagcgttgt tgttgttata
    36841 tcattttctg cgacgaaagc gaccttgtct tctttgctca aattaaaaga tatatcatct
    36901 aaaattttct ttccatcaat cgttacactt acattttcta cctgcaataa gtcgtttcca
    36961 atctcacgtt caggtttgaa tccaacgaat ggataacgtc tagaagaagg ttggatatcg
    37021 tctaaagtaa ttttttcaag cattttttta cgtgaagttg cttgttttga ttttgatgca
    37081 ttcgcactaa agcgggcaat aaattcttgg agttctttga tttgttcttc ttttttggca
    37141 tttgcgtttg cttgaagttt agccgctagt tgactagatt ccaaccaaaa atcataattt
    37201 cctacataaa gtttgatttt accaaaatct agatccgcca tatgtgtaca tactttgttc
    37261 aaaaagtgac ggtcatggga tacaacgatc acagtatttt caaaattgat caaaaattct
    37321 tccagccaat tgatcgattg gatatccaga ccgtttgttg gttcgtctag caaaagaaca
    37381 tcaggtttac caaatagtgt ttgtgctaat aacactttta ccttttgtcc accagttaat
    37441 tcactcattt gctgatggtg caattcttca gggatgttca gaccttgcag taaaacagct
    37501 gcttctggtt cagcttccca tccattaagc tcagcaaatt ctccttctaa ttcagctgct
    37561 cgaataccat cttcgtcagt gaaatcctct ttcatgtaaa tcgcatcttt ttctttcagc
    37621 acttcataca gacgcttgtg tcccatgatg actgtttcaa gtacagtata gtcttcatag
    37681 tcgtaatggt tctgtttcaa tacggccatc cgttcatctg gtcccatagt aacggaacct
    37741 gtggaaggct gcagatcccc tgataacact ttaaggaacg ttgatttacc tgcaccattt
    37801 gcaccaatca agccatagca gtttccgggg gtaaatttaa tattcacatc atcaaatagt
    37861 ttgcggtctg aaaagtgcaa actcacatca tttacagtaa tcaatttttt tcctcacttt
    37921 tatcattatt agttttgaca agtcttatag aattatatag gggaaaggta aaagattcaa
    37981 ggcaatcgaa cattctttgt gtttcacgtg aaacagaatg aaaaaaataa aaataaaagc
    38041 ggagcgaaaa tagctactat aggatttatt agtttgcaac agcataattt ttgacgttat
    38101 ttataagagg gagtactata aaactgtaaa agaaatgaaa gaaggattga aaatggatga
    38161 aaaaagaacc atcgactggg gctcattgat tttgggaatt ttatttgtac ttgtctcatt
    38221 gttatcattt caagaccctg tcggaaattt agttgcaatt gtagtagtct ttgcgatttt
    38281 tgcctttatt aaagggatat ttgaactgtt tgtacggaac agattaaaag agctaacagg
    38341 atataaagga aagatgccct taataatcgg gatcatcgat attctagttg gcgtcttttt
    38401 cttattcaat attggtgcag gagtcgcagc attgcctttt gtttttgcag tatggtttat
    38461 tgctgattca gttttagcgt tatttactgc tgacttggca agaggagtaa gtgaaggata
    38521 ttattggttt acgatcatcg tcaatatttt aggaatttta ttaggaattt tcttattgtt
    38581 taatccaatt tcttctgcgt tgacattaag ctttttagtt ggattctatt ttatgttatt
    38641 tggtatcaca catatcgtct atgcatttag ataagtaaaa tcaaacaaat aaaaaagccg
    38701 gcttccgatt acagttttac tgttgtaatt ggaagccggc ttttttatca tggacaaata
    38761 tgcacgaggt gatttttagg tgtcgagaca aatttatgca aaaatgtgag aagctatata
    38821 cacaaatttt atcttaatac tcgaagcata gcgcagttgt cacaacctct tttcatataa
    38881 ttcattcaat actggcaaat catggacttc atatttttct ttgaatgctt ggatttcttc
    38941 ttcagaatat tttcttggat ctaaatgcag atcttctact ggcaatgggc gcttgttatt
    39001 gatcttcaca tcgattacta caggacgatc tgattttgca gctgcatcaa aggcaaatcg
    39061 aagttgcgag tattctgtga ctgtaaagct atttgccccg agcgcttctc caactttacc
    39121 gaaatctgca tcttctaaaa atacaccaaa tttcttttgt tccgtatctt cttgttctgc
    39181 ttcgatgaaa ccaaaagaat cattcgaaaa gacaacatta ataattggaa gctgatattt
    39241 gacttgtgta atgatatctt gcatgaccat agcaaacccg ccatcaccac ttaaggtaaa
    39301 tacttgtttt tctgggtagc ttagttgtgc ggcaattcct cctggcacac cattacccat
    39361 agttgcgaac catccagatg tcgtatgttt ttgtttaccg ttcatattca ataaacgaat
    39421 agaatggata gtcgtgttac cgacatctgt gacgaaaatc gcatcgtctt cagcaatacg
    39481 attgatttct ttatagacag cctctggacg aatcggttct tcctctcgat cttcaaaaga
    39541 tttcaaccaa tttacccatt tttctttatt ttcttgattt gctaggtacc agctatcagc
    39601 agggcgagca tcccctaact cgacaagtct ttgcaaagct gtgtttgcat caccgaggat
    39661 cgacaaagat gtttcatggc gtcgtccaaa ttttgacgca tcgatatcga tttggataaa
    39721 ttcagcagtt ggattaaaaa atgcacgtcc aaatgggaag tcgctaccga caaataagat
    39781 cagatcggct tctgccaatg cttcatttcc gggtttagta gcgacacgtc cagcaaaacc
    39841 aagaaagttt tcataatcat caggaataat tccttttgct agaacggaag cgacaacagg
    39901 aactgaaaaa tgttctgaga attctttgat ttgcggaaat ccgtttcgcg ttccttgacc
    39961 aacataaaga actggttttt ttgctttttc aagataaggc aaagcagcta gcaaatcttt
    40021 ttcttctggt aatatcacac ttgttttgtg agtgtgagcg gtggagaaag gttgttcgtc
    40081 aatttcttca aaaccaagat caacagggat agtcacgata gccacgcctt tatgctcata
    40141 ggcggcttta atggcttcat ctactacatg cggaagactt tgtggtgtca tgactgtacg
    40201 attgtatacg ctaacatctg cgaaaatagg attttcattt agttcctgga aagagttata
    40261 gttcatggat gtagaagcaa cttgtcctaa gaacgctact agaggcacat ggtccatctg
    40321 tgcatcatac aaaccattga tcaaatgtgt cgcaccaggt cctgcagagc cgaagacagc
    40381 gccgactttc cccgttaatt ttgcatctgc agcggctgcg agtgcgccga cttcttcatg
    40441 acgaacttga atgtagttga tttcggtttt ttcttgatat agcgcatcca taattgaatt
    40501 gaaagatcct ccgggaatgc cgtaaatatg gtcgataccc cagctttcaa gaacttttac
    40561 cattgcgatt cctgcattga tttttgacat ggtgtttcac tcctttagca atgatgatac
    40621 ataaattttt tgtatctaga gtatagaact ttttatcgaa aatcccaact aattcgtctt
    40681 ttcacaaaaa tgtagtcatg tttttgggaa tatgctagag tagtacatag atagattcaa
    40741 gagaggggaa tggcatggtt gaatggctat tgagacttga accttggcag caagcacttg
    40801 ctgggacagc ttttacttat tttatgacag ctcttggtgc cgggttggtt tttttcttta
    40861 aagaaatcaa aaaagaagtg ctaaacttga tgttaggatt tgcttctggt gtcatgattg
    40921 ctgcaagttt ttggtctttg ttagatccgg ctattacaaa agcagaagaa aatggagata
    40981 ttgcttggct agttgtaagt attgggtttg gtttaggcgg tgtgttttta tatatggcag
    41041 ataaaacact gccccatatg cattttggac cacaacatga agcagaagga ttgcctaccc
    41101 atttaaaacg gacgatcttg cttgtttttt ctattacatt gcataacatt cctgaaggtt
    41161 tagccgtggg ggtagcattc ggtgcagcag caactgcgga taatccgaca gccgctatat
    41221 tagccgctgt ttcggtggcg ctaggtattg gtatccaaaa cttcccagaa ggagcagctg
    41281 tatcaatccc gttgcgacaa gaaggtctga gtcgtaaaaa ggcctttgtt tacggacaag
    41341 cttctggaat cgttgaacca attgctggag tgattggagc gctactagta acgaaagtgg
    41401 agctgctgct tccttatgca cttgcttttg ccgcaggagc aatgatttat gtcgtggtgg
    41461 aagaattgat ccctgaagca cagcagacat tgtccagcaa acgtcatttt gcagtttttg
    41521 gcgtcatgag tggatttatc attatgatga ttttggatgt ggcattagga taaataaaaa
    41581 aaatatatat gatatatcaa atagggccgc gaacttatat cgcgacccta tttttttagt
    41641 aagttatatc ataatgaagt gaatggtatc atacattaat aatagttttt tctatgtgta
    41701 tttcctttga tccagcgaac aagccagatg ataagtgcga ttgggattag aactttgacc
    41761 gcaaaccata aaagcccgct taggacactg acaaaaagac tgatgacgaa gctagctgca
    41821 attagcacta aaagaaccat gaagatattt aagaacatat ttttttgacg catacaaaac
    41881 cctcctcttg ttcattcttt actatagaaa aagtataaca gggattgttt aaaaacacct
    41941 ccaactgaag actgattttt acttcatcta cttaaatgat caaacaattg ctttttctct
    42001 ggtttatcat ctaaaataga gcggaaaagg aggagaatat catgcctaaa aatcgtcttg
    42061 aagcatttac agatgctgta atcgcgatta tcatgactat tttagtttta gaacttcatg
    42121 aacctaacgg agacacgtgg gaggcgctcg ctgcattagg ttaccgattt tttatctata
    42181 ttgtcagttt tatcatttta gcgatttatt ggaacaatca tcatcattta tttcaagttg
    42241 tacataagat aaatggacgg gtcttatggg cgaacagttt ctttgttttt gcgctttcgc
    42301 tttttccgtt tgcaacttca tggatcagtg agtacatcaa tagcctggct ccagaaatga
    42361 cttatggttt tgttaccttg accgctaata ttgcgtatta tatcttggca aaagaacttg
    42421 tcaaagcaaa taaaggccac gagaaagcat tgaaggcgat gttgaataat tacaagaaat
    42481 cgtatctatc gattggtttg aatgtgttag gaattgtctt agggtattta gtagcgccag
    42541 tagccgtgct gatcgcaaac atcgtgattc tagctgcttg gatcatccca agtcgtacca
    42601 tcgaatcaca atatcggtaa aatgatccgt gtttaaaatt taagagaaaa atatagaaaa
    42661 aataaataaa cgatcaaata tccgagtgat actagtattc aaagagggat gcagatggat
    42721 caaaaaagaa ttcatgtagg actgattact agttttgtca cgatgcttat ttatttggat
    42781 caaggtcatt tgacttggac agtagttggt gtcgtaggat ttttgacatt attcacagca
    42841 ataaaaaaat aaacatcttt atgtaatctg atgttctatc tatttaagaa aagcatgttt
    42901 acagcagtat gattctgttg taaacgtgtt tttatttgtg gaaaatttaa tttttagaaa
    42961 agtgtatcga aaaatagata gttagttttt ccacagtgga taacttcgta agagataaaa
    43021 ataaaaaatt agtcaaagaa gggcgtatag atttcttttg ataggagata tacaacagaa
    43081 atgaataaat attaacgtgt tttcaaacag tataaaacgg tgtggttttt ggaataaaaa
    43141 aataacatat ctcattttac acttttgtta ttttatactt aaaaaataac gacacagaaa
    43201 ataccgtgtc tcagatttct ctactacttc taaaaactac tgtttttttc ctttgaaatg
    43261 ccttcaaaaa gtaggatcag gcagaatata ctggcagaat caaggagaag ggagcctaaa
    43321 taaggagaaa aaccatagaa aatataaagt aattacttat aaaacaagct ttttatagaa
    43381 aaataatata cctgagtagg gtataaatta agacggaatt cctttctaga ttgagatatt
    43441 gactaggaag aatgttaaga ttttaagcct ttaagctaaa aaaaaaccct ttttgttaaa
    43501 taaggggaat atagcctgtc agtttcaaac tgcaagtcgt cctgctgcaa taatatagta
    43561 gattagagat gaaaatagat ttttttaaac caatgactga ataaaaagac cgtcatagat
    43621 acacattgga atgtgtctat tacggtcttt ttttacgaac gattttattg aagacggaca
    43681 gttcgggtca aaaataaaaa agctacgatc agaaataaga ataaaatgta tcccaaaata
    43741 atggctagac ggtctaactt atttgtcgat agatgtttgt ttagaagttg ataggcccat
    43801 aaacctatca gtcctcctgt tgtattagtt atcaaatcag tgatgtccgc tacgccaata
    43861 ccgaatagga attgaatcaa ttctgccaag aagcttacaa ggaaaataat ccctaatttt
    43921 ttagaaaaag aaagtctctt gaaattgaca ttcaaaagca ccccaaaagg aaaaaagaca
    43981 atcaagttat aagtggtctc acgtaatacc gtcgtatttt caaaagaaaa agtagaaaaa
    44041 gggacgagat tgacattgct gtaagaataa gtgagaaatt gtggaagatt aaatgatagc
    44101 ttgaataaaa tcaaccataa tagaaagaat aaataaatcc ctaataaaaa ttttgataca
    44161 taccgcatag acatctcctc catttaaaaa gtataccatc gaaaaccgct gaaaaatcat
    44221 aaaaaagtat gaagtttaag gaccaacgta gttatcgtac gaaaattaga agcttttttt
    44281 tgttgggaat ccggtttctt taacaaagct aagatagcga gttgcttgga aaagttgcta
    44341 tcttttttct gtcaaaacga ctcggaatgt tcgttttttg ttctaatttc tccaagttgt
    44401 ttactttttg atactaagtt tatgaaaaat caagaaatag ttgttatact aggtaatgct
    44461 gacaaacggg attggcattt catcttggtt cagctttttt tccaattact aggaaggagg
    44521 gatagattgt tcaagactta ttttcgtttc aataaaatac aagataatcc ttttcgtatc
    44581 atgaatctga tgctacttat ctttattgta ttatggttag gttacataaa tcatgatttt
    44641 ttgatttcaa gtttttcatc attagggatc tttacttttt tctattatca aaacataccg
    44701 atgaaatatt tgctgaaacg tatgtttctg atcggttgcg gactgttggt tgctttcgtt
    44761 ttggggatct tatcgactta tgttttatgg cttgaaccat ttgccgtagc tttggttgct
    44821 ttttccagca gattcgtgtt gcgattattc catatttcta aaccaggtgg cttgtttttt
    44881 gcgatgcttt ctgccatggg aacgagcatg cagctgccaa tcgctcaatt accgatcgtc
    44941 tcactttatt tttttatggg tgtcgttttt gccctgattg cggcagtgat tacaaaatta
    45001 ctggattcac ggcctgagca gacaattgaa aaagcaactt taaaagaaag atttcacgaa
    45061 gagcctttag tgatcattga ttctgttttc tacagcgctg ccttatttct ttccgtttat
    45121 gtcagtcacg gcttgaatct gcataatcct tattggttga ccttgtcatg tgcatcgatt
    45181 ttgctagcag aaaacttgga tgcgatgaag catcgacaag tccaatatct gattggatcg
    45241 atgggtgggt tatgtgtgtc ggcattcttg tcatttgtgc cgtttacgca gttgcagacc
    45301 atttttctga tcacttttct atatggaatc gcacaatttc tagttgctag aaattatgca
    45361 gttgctaata tttttcttaa tccgatggcg ttgatgctat ctacacttat tcgtggagca
    45421 tacttgattt ctttgatcga atatcgtttt ttagggatcg tcataggaag tttcatcggt
    45481 ttaggtgttg cgtgggtaat gacggttggt ttgcaacatt atttaacggt tgttcgtcaa
    45541 aaattagaat agaaggacaa atatatgtgc caaaagaggt tatgacaaga tttttgtcac
    45601 aacctctaat tcaaggtgtt caaaagccag attctcagca ttaagtcaaa ttcacacaaa
    45661 aatgtggaaa ggaactttca aaaaaatttt atatttattc tatcaaaaaa ttttgtttat
    45721 gatggtaact gaataaactt tcctgagatg gtcaatgctt tccttgaaag tcttacagat
    45781 attctttctt catagaaagt ttaagtttta tagttagtgt acaataaaag tatgtttata
    45841 ccatatggtg tccggataat cagtcattta aacaatgagg ttcaaagata tgaaaagggg
    45901 aaatttgatg aagaaaataa gcaatgaaat ccaaattctg gcagaaactt taactcttcc
    45961 caaagtcgtt atagagcaaa tgattgtaca agcaaaaaac atccttgatg aggtgtttga
    46021 gcaatatagt catgaactaa tggatcctaa taaagcaaag gcgactgcaa agaaaataga
    46081 caaagtctat gaagaggaac cttttgcagc attagctatt tatctatatg cagcttctca
    46141 aagttggaaa aaaatttatc aaccattgaa gattccaaga actatctatt tggcaacaat
    46201 gaatgctttt actagattta ttcatgaaca tttccaagta acaggaagct atcgctttga
    46261 ccgtggtttt tggatttggc attacactag tggcttgatc tttcggattg gtgaattgga
    46321 gtacgaaatg acatattttc cgaaagggta cacggatcta agattagaag gaaagcagtg
    46381 cctttctctt catattcctt ccgatgcaga tttatctcag aataagataa gagatagtta
    46441 cgaaagtgcc attcgttttt ttgaacttta ttttcctgat taccattacc aagtgatgta
    46501 cacagatact tggttactat cacccaatct tactaaatgg ttgaaaaaag agtcaaaaat
    46561 ctgtcttttt gcagccgatt atcgattatt atcagttgat gaacaggacg atagtggagt
    46621 cccttggatc tttggacgag tagatgccca aatacatgat tatccagaaa gtacgagttt
    46681 acagcgacaa gcaaaagagc aattgcttgc aggcgagcac attggctctg gcttaggtat
    46741 tcttacttca taagtttagt acttcgaaat agtttaaaag agcgtgagac aaaagtaaag
    46801 aacacttttg tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg
    46861 gaaataagct gaaattcaca aaaatttgaa aagcaatttt cgtgaatttc ttcttatttc
    46921 ttggagttaa acgcttctgt cccagcctct tttttagtgt tctatcgaac acacagtacg
    46981 ttcaataggt aaactagcta taacaataga tattaaagtt aacggacaag agggcctttt
    47041 ttaggtagct aaaacgtaat aatgaaaatt tatttccaga gataggagtc aatcagctag
    47101 tctgatcgac tgttttaaca agttgacttt cattttaact tttgatacca tttaaaacac
    47161 aaatcgtaat tgtttcgatt tgtgtttttt agcatgacta caatcaaaga agaaagtggg
    47221 tcgtccatat ggaaaaaaca gatatctcaa gtgcataccg ccgcttgaaa agcccaaata
    47281 tcaaaacacg aaaacgtgcg ctgaagatca tcaaagatgt gaaacggaat agtgggaaaa
    47341 ggtaagaaga aggaaactta attaaaaaaa tagccgaaaa acgtttttcg gctattttca
    47401 ataatcggtt tttgtgtaag gtttccgaaa gaactgctgt tgattttcca tttttaacat
    47461 atgataaatt ggtagaatct ttcttttcaa attgatacca ttccctaatt ccagttatat
    47521 agttaactac agaaccacaa agcacgtacg tttataaaag tattatctgt agttattttt
    47581 caattccctt tcaacctctt attttgacca gtagtattga tcactttacc ttttaacacc
    47641 tttgttcgtt tttgaaacat ttttagtcaa gaatggaaac gtaactacat aatcaaaggt
    47701 tttgcgaaat atttcatgaa atatttcatg tagaagcgag caatacggtt gcaaataacc
    47761 attatcgttt aataagcagt tacgaaagct cccaatatct ctaacgttca gctcactcca
    47821 tttcttttct tcaaaaaaat cagtgattcg tatctctttc tatttgtcga aaaagttaac
    47881 tttaaaaagt aacgccgaaa aaatatgcaa aaaaataaaa aagcagttac tattgctaga
    47941 ataacatcaa ggaataataa gttttggttt tcagataata gtcgataagt tgtgtattgg
    48001 aattttagat acagtaataa agtatttttc atgaaatttt gtgagaatca ctattacaag
    48061 tatctttaat aaaattaatg gttaaggagg aacttaaagt agaatgtaaa tgaatagttg
    48121 tagtcagtcg attgtgatac tagactcaaa gttgcaggaa taagtttttc aatttgtgat
    48181 tggaagataa aaaatgaaaa agaagggctt ttttttatac tttgttgatt gtagtgttta
    48241 ttttccctct gtttagccaa gtaacatttt ctatgactca accagtttca agtgaggaac
    48301 atgataacct ttttcgtgct acagaagagt ttaagaaata tcaggaaaat attgttccgg
    48361 agactccatt agctagtgag ccaattactg atattgatgg aaaccaaata ggatggtata
    48421 tacagtacga agttatggtg gtaaataatg actcaatagt aaaaaataca gtaggcttag
    48481 agctaacacc gattgaaaag gtgagttcat tgttaacgta tatttatact gatgaaagtg
    48541 acgagactga gatcatttta acggattact caaaaattgc tactgataaa aagtatatat
    48601 tgtggatgta gacactagtg aaatacttta tgatatagaa attgatgaaa atttactaga
    48661 tgtagcacaa gaaatcgatc atcaaaagca ggaagctatt cgatatgctg gtagaaaagg
    48721 gaaaagaaaa tatttattac gtgaatgtag caaaagttag agaagatgaa aatgagtgga
    48781 aagaattcaa gagtcgctac tcaattaact cgactccgac atttacagtt tacagagaag
    48841 gatcgataga aaaaactgtt ttttggacta aagaaagtgg aatgtcttta gctgaagtag
    48901 aagagttttt ggattatgtt agtatgcaac agtaagggag ttcttattat gaaaaatttt
    48961 gacacatatt atgttattgt tttttcgata tctttgctgt taatattact aactttaatg
    49021 cagtataaag agtatccaga gtattttatt ttaacttttg tatatttagt aagtagctac
    49081 acacttctat ataaattcag aagttcttct agagttt
//
LOCUS       DAPBBV010000021        48809 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.021, whole genome shotgun sequence.
ACCESSION   DAPBBV010000021 DAPBBV010000000
VERSION     DAPBBV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.021"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..485)
                     /locus_tag="RD486_001445"
     CDS             complement(<1..485)
                     /locus_tag="RD486_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663180.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     K"
     gene            complement(496..1164)
                     /locus_tag="RD486_001446"
     CDS             complement(496..1164)
                     /locus_tag="RD486_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDT7663181.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(1294..1878)
                     /locus_tag="RD486_001447"
     CDS             complement(1294..1878)
                     /locus_tag="RD486_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7663182.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(2209..2442)
                     /locus_tag="RD486_001448"
     CDS             complement(2209..2442)
                     /locus_tag="RD486_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HDT7663183.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(2457..3407)
                     /locus_tag="RD486_001449"
     CDS             complement(2457..3407)
                     /locus_tag="RD486_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDT7663184.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(3404..4246)
                     /locus_tag="RD486_001450"
     CDS             complement(3404..4246)
                     /locus_tag="RD486_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7663185.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(4248..4967)
                     /locus_tag="RD486_001451"
     CDS             complement(4248..4967)
                     /locus_tag="RD486_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7663186.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            5659..5817
                     /locus_tag="RD486_001452"
     CDS             5659..5817
                     /locus_tag="RD486_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663187.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            5889..7115
                     /locus_tag="RD486_001453"
     CDS             5889..7115
                     /locus_tag="RD486_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7663188.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(7203..7595)
                     /gene="rpsI"
                     /locus_tag="RD486_001454"
     CDS             complement(7203..7595)
                     /gene="rpsI"
                     /locus_tag="RD486_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDT7663189.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(7611..8054)
                     /gene="rplM"
                     /locus_tag="RD486_001455"
     CDS             complement(7611..8054)
                     /gene="rplM"
                     /locus_tag="RD486_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDT7663190.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(8573..9040)
                     /locus_tag="RD486_001456"
     CDS             complement(8573..9040)
                     /locus_tag="RD486_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HDT7663191.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(9160..10698)
                     /locus_tag="RD486_001457"
     CDS             complement(9160..10698)
                     /locus_tag="RD486_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDT7663192.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            10778..11464
                     /locus_tag="RD486_001458"
     CDS             10778..11464
                     /locus_tag="RD486_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDT7663193.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(11665..12192)
                     /gene="msrA"
                     /locus_tag="RD486_001459"
     CDS             complement(11665..12192)
                     /gene="msrA"
                     /locus_tag="RD486_001459"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7663194.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(12276..12953)
                     /gene="pgmB"
                     /locus_tag="RD486_001460"
     CDS             complement(12276..12953)
                     /gene="pgmB"
                     /locus_tag="RD486_001460"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDT7663195.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(12950..14080)
                     /locus_tag="RD486_001461"
     CDS             complement(12950..14080)
                     /locus_tag="RD486_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7663196.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(14080..16263)
                     /locus_tag="RD486_001462"
     CDS             complement(14080..16263)
                     /locus_tag="RD486_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDT7663197.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(16260..17285)
                     /locus_tag="RD486_001463"
     CDS             complement(16260..17285)
                     /locus_tag="RD486_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7663198.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(17330..18157)
                     /locus_tag="RD486_001464"
     CDS             complement(17330..18157)
                     /locus_tag="RD486_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7663199.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(18154..19221)
                     /locus_tag="RD486_001465"
     CDS             complement(18154..19221)
                     /locus_tag="RD486_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HDT7663200.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(19247..20083)
                     /locus_tag="RD486_001466"
     CDS             complement(19247..20083)
                     /locus_tag="RD486_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7663201.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(20080..20949)
                     /locus_tag="RD486_001467"
     CDS             complement(20080..20949)
                     /locus_tag="RD486_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7663202.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(21019..22302)
                     /locus_tag="RD486_001468"
     CDS             complement(21019..22302)
                     /locus_tag="RD486_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDT7663203.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(22316..24001)
                     /locus_tag="RD486_001469"
     CDS             complement(22316..24001)
                     /locus_tag="RD486_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HDT7663204.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            24276..25301
                     /locus_tag="RD486_001470"
     CDS             24276..25301
                     /locus_tag="RD486_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7663205.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(25896..29570)
                     /gene="rpoC"
                     /locus_tag="RD486_001471"
     CDS             complement(25896..29570)
                     /gene="rpoC"
                     /locus_tag="RD486_001471"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDT7663206.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(29628..33245)
                     /gene="rpoB"
                     /locus_tag="RD486_001472"
     CDS             complement(29628..33245)
                     /gene="rpoB"
                     /locus_tag="RD486_001472"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDT7663207.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            33973..34941
                     /locus_tag="RD486_001473"
     CDS             33973..34941
                     /locus_tag="RD486_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7663208.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            34959..35864
                     /locus_tag="RD486_001474"
     CDS             34959..35864
                     /locus_tag="RD486_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663209.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            35861..36667
                     /locus_tag="RD486_001475"
     CDS             35861..36667
                     /locus_tag="RD486_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7663210.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            36803..37792
                     /locus_tag="RD486_001476"
     CDS             36803..37792
                     /locus_tag="RD486_001476"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDT7663211.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(38109..38633)
                     /locus_tag="RD486_001477"
     CDS             complement(38109..38633)
                     /locus_tag="RD486_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HDT7663212.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            38920..40731
                     /gene="scm"
                     /locus_tag="RD486_001478"
     CDS             38920..40731
                     /gene="scm"
                     /locus_tag="RD486_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HDT7663213.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(40886..41872)
                     /locus_tag="RD486_001479"
     CDS             complement(40886..41872)
                     /locus_tag="RD486_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDT7663214.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(41895..42461)
                     /locus_tag="RD486_001480"
     CDS             complement(41895..42461)
                     /locus_tag="RD486_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDT7663215.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(42475..42891)
                     /locus_tag="RD486_001481"
     CDS             complement(42475..42891)
                     /locus_tag="RD486_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDT7663216.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(43348..45282)
                     /locus_tag="RD486_001482"
     CDS             complement(43348..45282)
                     /locus_tag="RD486_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7663217.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            45563..46519
                     /locus_tag="RD486_001483"
     CDS             45563..46519
                     /locus_tag="RD486_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDT7663218.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            46609..47712
                     /locus_tag="RD486_001484"
     CDS             46609..47712
                     /locus_tag="RD486_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDT7663219.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            47725..48678
                     /gene="menA"
                     /locus_tag="RD486_001485"
     CDS             47725..48678
                     /gene="menA"
                     /locus_tag="RD486_001485"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDT7663220.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
BASE COUNT        14492 a        10101 c         8844 g        15372 t
ORIGIN      
        1 aatttagagt ttagcgataa actacatcca atagaaattt tctgccgttc accacttgat
       61 agcgaaaaaa tgtttttatc taatatattt gaaagatcta ataattcagc taattcattg
      121 attcttttat ccatatgctc ttttgtaaat ccaaagtttt ccatcgaaaa tactaactca
      181 ctcgttgtat ttgttgtaaa gaattgtcct ctaggatctt gacttacgta gccaatattt
      241 tttgatatac tttcttgtgt taaggattgt agcgagttat tttcaaataa aatttcccca
      301 accaattttc cgtcataaag tcttggaata agtccattca ttaactttaa tagtgtggat
      361 ttcccactcc cagaagaacc agtaatcaat gtaagactgc ctttttttat tgaaaaatta
      421 aggtcaacaa gcgcttgttc cttaacatcc ttatatgaaa aagaaacatt gttaaattca
      481 aacaattctt tcacctcaaa tcaaaatact taagaaaaaa atagtaacgg aaaacaggat
      541 gatatagtct aataagctca tgtttgtttt atagtaagaa cttcttttca caggagattc
      601 tatccccttt gttattgcat tagcggtcat ttcttcagca atcatagttg cacgtataag
      661 aacgggaact aacagaaatt ccaaatattg cagaggctga aaaaaagaca agcgaatgtt
      721 tctcattttt aaagattctt taatcattct tatttcagaa cgataagtcg gaaagaatct
      781 gatcactact gtaatactta acattatttt tttcggtaaa tgtatttttt ctaaagagga
      841 taataattca ttgctagtat agacactaac caacaaccat gagatcatta cgaccggcaa
      901 cattcgaaat acaatatata aggatgtcgc aaaaaatata gtaaaaaact ctatcttgat
      961 agcatcaata attttcatta ctaaaaacag aactgaataa atcaagatga aataaataca
     1021 tgtctttatt ttacgaaaca tcaatactaa aactgtagca ataatgaaac accccacttg
     1081 aaatatattt ccctttccta aaaaaataat gaccggaaaa aaaatattta aagtaatcaa
     1141 ggttaacgga ttgatttttg acactctttc acctccaaaa aataagatcg cactgttatc
     1201 ttaagctgat aaaaatgcac cgttattcag ataacagtgc gatcttatca aaaagcataa
     1261 ctgagaacaa ttctcaatgc aagctttttt taattaactc agtaattcaa tccacccagg
     1321 aacagaaaat tgatacaatc ttctggttaa tagcatagtc ttttcttttg aatagctatg
     1381 cttcaatata tcatagaatg tagcgtagaa tgagtaaatg tagaagtgga tttcttcttc
     1441 attaaagact aaattttgat tgatcattcc gatagtcttt aacttatcta gacaacagac
     1501 tgtctttttc gtcacaaatg atgtaatttt ttcaacaata tcttgatatt tggttccagc
     1561 tgattggaat aaaatcaaat cgaatatacg tttattctca aaaatataat taataaatgg
     1621 atctaattca ttgaagttct ctctccaact tttctctata tctatatttt ctaagtttaa
     1681 gaggtatttg gtaaactctt cattatacat attaataagc gcattaatat gcggctgaat
     1741 aatttcttca aataacgctt ccttagaagt aaaatgttta taaaaagcac ccgtagttac
     1801 gcctgcggtc aggcacagtt gccttatctt agtttgctga aatccttctt tttcaaaatg
     1861 gcttagtcca ctttctatta acttttggtg agttataata taatctctgg tttctatggg
     1921 tacttcctcc taataagatg aattaacttt attatcttac acaggacttg aagtttcaat
     1981 cgttaacgtt tattactgaa ctcattcctt agagctaaac taatgagaaa gagcagaata
     2041 actgatacaa aaagcaatcc tacaagaatt aatagactca tctaaatcat tcaccttttc
     2101 taaaataatc cgagaaagat ttaaaaaaat tatatccagc tattaggata agtcctatca
     2161 taatcactcc aatagccatt ttcttatcct ccctaaaaat aaagtctttt acttaaaacc
     2221 ttttttgtaa tcgtcaataa attttttccc tttatcagtt aattgaaatc ctatatctaa
     2281 atagtcctca tatctaagtt tagccagcat ctcacttaca gatgctggac taacacttag
     2341 aacttttgct aaatcattat tttttaattt cttttttctt tttgataatt cctgaattgc
     2401 tagtaaataa attagtatag tagtcgtttt aatttgtacc atacctaccc tccaaattat
     2461 ttcgaaaggc cttcagcaat tttatccagg ttccatttca tcatcgcata gtaactatca
     2521 ccatcttgtc ctttttctgc aattgaatca gtaaaaatcg ttgaatagat aggaatattg
     2581 gtatcttttg atactgtttt cattggtcta tcatccacac tgctttctac gaataaggag
     2641 ggaacttttg ttgtgcgtaa tttttcaact aagtgtttta tttgatctgg tgttccttct
     2701 tcttcagtgt tgatttccca aatgtaagca gaaggcacat tatacgcttt cgagaaatat
     2761 ttaaagcatc cttcacttgt aacaatcatt tttttatcat tcggaattga agcaaattta
     2821 gatttagctt ctttgtctag agaatccaat ttttcaatat acttatctag attttcttta
     2881 tagaattttt tattatcagg atctttttcc gctaactgtt tttcaatatt tttagcgtaa
     2941 ataataccgt tttctaaatt taaccaagca tgaggatctt ccttcccttt ctcactctga
     3001 ccctctaagt aaataacatc tatgccatca cttgctgcaa aatagtcttt gttttcctct
     3061 ttgttcgcat ttttaactaa ttttgtaaac caagcatttc ctccagtttc caagttaaca
     3121 ccgttataaa aaatcaaatc tgcttttgaa gttttttgaa catcttcagg caaaggttca
     3181 tattcgtggg gatctttccc aataggtacg atactgtgta aatcaatttt atcttttgct
     3241 atattttcgg taatatctgc taaaatcgaa ttagtaacta ctacttttaa tttttcgttc
     3301 gaagccactt tatctttgtc tttactattt attgaacatg ccccgaatat aaaaagagca
     3361 atcaaaatcc ccagacttcc cagtactgct ttccattttc tcatcataac gatctctcct
     3421 tctttcttaa aaatttttgt tttggtgaga ttagaaaact aattacaaat aagaatgccg
     3481 ctgttaaaac aatacttgat cctgctgcta tgttaaaact ataaccaata aacaatccaa
     3541 gcaatgatga acttgctccg actgttgcag aaataaatat catagttttc aagctatttg
     3601 catataaata tgctgtagct gctggtgtaa ttaacattgc aacaattaat atagttccca
     3661 cactttgcat agctgttact gctactaaag ttaatagaac catcaataga taatgataaa
     3721 aactgacatt catccctatt gcttttgcca ttaatggatc aaaagaagtg attaataatt
     3781 ctttaaaaaa tagaactact ataaccaaca ctaaaaccga aacgccaatt gtaatccact
     3841 tatcaatatc ttgtacagct aaaatatttc caaataaaat atgaaataaa tccgttgagc
     3901 tatttgcaac tcctataagg ataactccta gtgctaaaaa agaactgaaa gtaataccaa
     3961 ttgctgtatc tccttttatt acactattgc tttttataaa agtaataatg atagaagcta
     4021 atagaccaaa tacaatcgca ccaataaaaa aattaatacc taaaatataa gaaattgcta
     4081 ctcctggcaa aacagcatga gaaatagcat cacccataag agacattcct cttaaaataa
     4141 taaaacaacc tactgttcca gaaacaatcc ctataactac agatgtaatt agagcattct
     4201 gtaaaaagtg aaagtcatac agaccattaa taaaattttg aagcatatta ttccccctct
     4261 ccaataaata tagtatctcc ataggctttt tttaaatttt cttcattaaa tacagattct
     4321 acacttccgt gagcaattag atttcgattc aaaagaataa tattatcaaa atacttcttt
     4381 accttgctta aatcatgatg cacaattagc actgtttttc cctgatgttt caattttttt
     4441 aacgtatcca taattattcg ttcactaact aagtctatcc ctacaaatgg ttcatctaaa
     4501 aatatgaaat ccgcattttg agcaagacat cttgctaaaa gtacacgttg aaattgtcct
     4561 ccagataatt ctcctatttg atgattagaa tattttccca tatcgacctt ttccaaagcc
     4621 tttgaaactc tttgccattc tgcattttta attctttgaa aaactttcat tccggcatat
     4681 gttcccatag atacacattc ttttactttt attggaaaag taaaatcaat atcagctttt
     4741 tgctctacat atgcaatctt caccagtttt ttattgatat cttcattatt aatggagacc
     4801 tctccctgat gagggataat atttaacatt gctttaagca atgtggattt tccagcacca
     4861 tttggaccaa taatacctgt taaagcacct tcttgtattt ttaaagaaat ctcgttcaat
     4921 gctaaaaaat cgttataaca aacattaagc tttttcactt ctaacataac tttctccttc
     4981 taaatgataa tgattatcac gatcatatgg tatacaaaaa ttatatttta gtcaacccta
     5041 aattttatag tttagatttt tttctgttgc tgaagattag aatgacaaaa ctatttgaaa
     5101 ctacgcgtat agtaagtagc tttcaaaata tataaaaaag gagcgttctc aaatgagaac
     5161 atgctcctaa aactacttta ttggcgtatg gaaaaattat acttgaagtg gatagcgggt
     5221 tgaataagtt gataagcatc aaaacattta taaaaattat tcaagactat gtctgttcca
     5281 tatacaaata tgaaaatcag taaactccat ttaacttttt tcgtagtgtg tctttttata
     5341 catgtttatc gttattaata gtgaatagga aaaaaactat ttttgatcat tgacaattaa
     5401 atacaatttt tgaataacga tccctgctat tcgagctaga aactcaagta cgccatgacc
     5461 tgattagcga caaatactta gagatttctt tttgttctgg gaaaacaaaa tgccatgaca
     5521 atagcagcaa ataatgatac ttccgtaagg ctcgccgtaa actggggaga ggtgaaattc
     5581 ctatgtgctt acccaaagca attcaaaaat ttcataacta ctattttagg agatgatttt
     5641 atagaatcca gagtctacct gaataaaaaa caaacctgtg catttctagg aatcgataat
     5701 aatactctag ataagtggat tcgtatatat aatttcccag taataagagt tggtggtgta
     5761 gttcgctttg acgtagaaga tattaaagac tttatgaata catttaaaat aacttgaaat
     5821 tttcttctcg ccgcatatac taaaattagt gaaatatact gccttacttt ttttaaggag
     5881 tgaggatttt gcctacaaag ctttcaaatg ggaaatataa aactaatctg agatatccaa
     5941 aaaggtttaa agaaataaca ggaattgcat cagaaaagta tcaaaaaaca tttccaaata
     6001 ggcaattggc gattaaagcc gaaaatgata tgaagaagaa aatagaaaaa gttttgagag
     6061 aggagaatgc aaactcatta gaattaaaag gaaaaataac gtttaaaaaa ttttacgaat
     6121 ctaaatggct tcctagatat gaattaggtc aaacaattag atcaaacagg cctcctagtg
     6181 atataaccat tagtaataca aaagatatat ttcggttgca tattttacct atgtttggtg
     6241 aatacgcaat gaattatcta aatatcaata ctgagataat atcagatgaa ttaaccaaaa
     6301 aatcgaaaga atatgcaaat ataaaaatca taaaaggata tgttcgttcc atgttcgata
     6361 ttgcagaaat actaaattat atcgaattta atcgaactac taaaattatt caaagtatca
     6421 ctgcacctaa aaaaaatgct ttagaagaaa aaagaataca agaaggtaag caagcactat
     6481 catcaaaaga acttactaat tggatagaag cagtaaatga tgattttaat aatcatttac
     6541 ttacttttca tgattacaca ctttttatga ttaccctgta tcttggtgat agaaaaagtg
     6601 agacttacgc tttgcaatgg aaatatattg attttgaaaa acaaacggtc cgtcttaaac
     6661 atactttaga taaatatcaa agaaaaaagt ttacaaaagg tcgaaaggat accgtcattc
     6721 aagtaccaga agttgtaatg acattgctaa gtgaatggaa atcggtacaa gctgatcaat
     6781 tgttgaaatt aaaaattaag caaacgttag atcagtatct ctttacttat actaaaccat
     6841 ctggagaagt aaattgtcct gttcatgccg attacctaaa ctatcgaatc aattcaatta
     6901 aaagaaggca tcctgactta gttcatttat ctccacacaa actccgtcat acttatgcaa
     6961 ctatagctag acaaggtgga gcagatatga atcaaatttc aaatgcttta acacactcag
     7021 atatttctac aacaaagata tatgtgaaca caccagatat agttgataag gctgtttttg
     7081 aagcttttca gagaggattg aataagtgtg attgatatgt gttcttaaat gtgttcttaa
     7141 aaacaaaaga agcactttcc aaataattga aaagtgccag aaacgttgat atataaagga
     7201 tattaacgtt ttgagaattg tgaagcttta cgtgctttct taagacctgg ttttttacgt
     7261 tcgaccatac gtgcgtcacg agtaagtaag ccagcacgtt taagagctaa acggaagtca
     7321 ggatcaactt ctagcaatgc acgagcgata ccatgacgga tagctcctga ttgtccagcg
     7381 tatcctccgc cgtttacgtt aacaaatacg tcatatgcgc cttttgtttc agtaacagcg
     7441 aaaggttgat tgattacttc acgcaagtca gcatgtggaa tgtattcttc aacatctttt
     7501 ttatttacag taattttgcc agttcctggt actagacgta cgcgagcaac tgcgttttta
     7561 cgacggcctg tgccgatata ttgaacttgt gccaatgaaa ttccctccta ttagattaag
     7621 tttgtgatgt ctaaaacttc tggttgttgt gctgcatgtg gatgttctgc tccaccgtat
     7681 acgttcaatt ttgtaaattg tttgcggcct aaagtgtttt taggaagcat accttttaca
     7741 gaagtttcga tcaaacgacg agaattttta gcacgcaatt cgccagcagt gattgatttc
     7801 aatcctcctg ggtagttgct gtgacggtaa taaattttgt cagtcgcttt tttacctgtt
     7861 aatttcactt tgtctgcatt gatgacgatg acgaaatcgc cagtatccaa atgaggtgtg
     7921 aaagttggtt tatttttacc acgtagtaca gatgcaacaa ctgttgaaag acgtcccaat
     7981 ggaacatcag ttgcgtctac tacataccat ttacgttcta cttcgcctgg tttggccata
     8041 tatgttgtac gcacgttatt ttcctccaat ttaagttctg atgtttgaca tacacttcga
     8101 gtttccgggg ctctttgtgg ggcaaacaat accatttaac atattacccg ctaatctagt
     8161 caatgtcaac gtttttctgc ttgattgaaa aatttatatg aaactttact tcttttcttt
     8221 cttttatata aaagggtcgt ttcctgtcaa aatgaaaaac aaaaagaggc tgtgacaaaa
     8281 gtcttgtcac aaccccttat tttgaataaa cggtgttctc ctgccaactc ctcggtcaca
     8341 agtcacaata tccataaaac ataagaagct gttttttaaa attgtttctt gtgactcgga
     8401 gctgaacggc aggcttacaa cctcttggta aacggtgttc aatcagctga ccctcggtat
     8461 tagctcaaaa aacggcaaaa tatgaggaac tattttgacg tttgtttctc taatactcag
     8521 gtcaaaacgc tgatttcaca acctcttttt cggtcaagtt caacaacagt ttttacgcgt
     8581 cgatctctgg cgctttgccc aaatgagctt ggatcatcca gatacgtttt tctgtggctg
     8641 ttttgaattc gataaagata tcttgtgttg gatcgtcgcc ttcttctcca gaaacttcga
     8701 ttcctttttg gtaaagatct gctagataac gatagcctgc aacaagtgtt tccaaacgtt
     8761 ctggaatagt acgatcccag cggccaattt catcagggat ttttgtgtta tctgcaaatt
     8821 cacgcaatgt agaataaggt gaaccgtcta atgtgatcaa gcgttcggat acttcatcta
     8881 actgagcgtt caaatcatcc atgaactcat ccatcattgg gtgcaatgta aggaaacctg
     8941 gtcctctcat gtaccaatgt gtttggtgaa caacaacaga catttggctt agatctgcaa
     9001 ctaattgatt taatacttct ttggtttgtt ggaatttcat ctttcttgcc tcctaacatt
     9061 ttcttacact taaaataata gtagactttc aatgaaaagt acaacaaaat catttacctg
     9121 agaacgattt tcagttcgct tttttatccg taaagccaat catttttcag aatcagctaa
     9181 ttcttctcgc agttgagcaa attgctgata agtctgtgct aaatgctttt gtgtcgaaac
     9241 aaataatgga tagattttct gatatttttt atgatcagtt tcttgtactc caacttgctc
     9301 tttcaattct atcaattcct gtgcttcact gatactttgg atctttccga tgcttctcca
     9361 gcctaaaatc acagctccta atgcggatgc ttctgtgaca gtagggaaaa caagcgggta
     9421 acccagtaca tcagccatca tctgacgaaa aatcggagat tgagcaaacc cgcctgtagc
     9481 acggatctct gtgagctgat tttcctggca aactcctttt aaaatccgat aaaggttgag
     9541 acagatccct tctagaatcg ccttcatcat ttctttttct gtatgttgcc gctgtaaacc
     9601 gataaaactg ccaaacgcat ctgcgtccca aagcggtgct cgctcaccaa gtaaataggg
     9661 atgaaaaatc agaccattgg cacccgctgg cacaaaagcg atagccgaaa gcagtgcatc
     9721 atatggattt tctccttttt ctttagcaga ttgaacgact tcctgtaaaa atgtatgccc
     9781 tgcccaatca aagatgccag caccattgct agtcgctcct cccactaccc aatgtttctg
     9841 atccagaaca taacaaaacg tctccatttc tggatggaac tgaggctgag tagtaataaa
     9901 acgaagtgct ccgctcgttc ctacggtcaa agcggcgatc gtatcaccaa aagcacctaa
     9961 ccctagatta gaaagcggcc cgtctgcccc tcccaaaaca aatgatatat catttggcaa
    10021 acctagttct gctgctgttt ttgatggtag acctgttact tgataggtgg aaggaaagac
    10081 ttgcggcaat tgctctattc gaatgttcaa gtagtcaagc acttcttctg cccattggaa
    10141 ttcatggata tcaaaatatc cagttcctga agctgttccg tagtcgctga tcagttcgcc
    10201 aaacaatcta taaaagatat agtctttgat accgacaaaa taagcagttt ttttgaataa
    10261 ttcaggttgg ctgttttgca gccacttgat tttgttcaat ggtgtcattg gatgaatcgg
    10321 cgtcccagtc tgccgataaa attctttgcc aagcacggta tatttcagtt tttctgcttc
    10381 gtccgctgct cggttatctg cccaagtgat cattcgagat aacggtgttt tctcttcatc
    10441 caacaatatc aggccatgca tcgcagagga gaaggagaca aattgaatga ttgtgtctga
    10501 aggcaactgt ttaattactt cttttataac ggtgcagaca ccttgaaaga tcaattcctg
    10561 atcttgttct gccatccctt gtgtttcttg gatcaaaggg tagcgaaaat aagcggatgc
    10621 tgcttcttgg gcttcatctg tgaaagcaac tgctttggtt tgtgtggttc cgatatctaa
    10681 tccgattgaa acgttcattt tttcacctca aattttatgt atgtacaaaa atttagttta
    10741 agcttgcgta tcttggtttt gaaaaggggg agatggcgtg ttactttatt ttatcattgg
    10801 ttgctgtatc ggatcatttt tatgtttaac cgcccagcgg attccgttag gtcactctat
    10861 tatttatcct agatctcatt gtgtcaaatg ctgtcgttcg ctttcttggt atgaattgat
    10921 tccgattctc tcgatcatcg tccaacgatt tcgctgccgc tattgcaggt gtcggttgcc
    10981 cttctactat ttgttggcag aagccttatg tggtggtctt tttgcctggt tctttacttt
    11041 ttcttccgca agaaattttt cgacgttcat atggatgctt tcggctttgc tattttcgtt
    11101 gatggattta ttttacttca tggtccattc tcacacgcta ttctgttctt gggcaatttt
    11161 atggattttt tggttgcagg ccggcgtctt ccaatggcaa agtgtgctgt taacgtttat
    11221 cgtaggcggt gtgtgccttc gctatggtca atcctatctc ggagctggcg atactctgtt
    11281 gatgctttct tggagtggtg gcttgtctct agaagagttg cttcagatct tgtttcttgc
    11341 tagtctgttt ggaatatccg ttttttctgt ttactttatc tgtcataaaa aaaagttgga
    11401 aaagctgcct ttcattcctt ttttgagcag tgcgttgctg attgtccttc atcttaggta
    11461 ttgaaaaaag gttgtgacaa acgacttgtc acaacctctg atatatagtg ttctcttacc
    11521 aaatccttgt gacttggagc taggcgacag gttcacaacc tctccactaa atggtgttca
    11581 atcagctgac cctcagtatt agctcaaaat gctggtttta caacctctga tatacggtgt
    11641 tccataagta gctttttcgg cttcttattt cttgacgccc caatgtcgac gaaggaaacc
    11701 tgcacgtcca gaaccttctc gataaagatt gtaatggagc ttgtttttct tgtaataatc
    11761 ctgatggtaa tcttctgcag gataaaattc gcttcttggt tcgatttttg tcacgattgg
    11821 cttatcgaat cgcccgctgt cttgcaatgc ttgttttgaa cgctctgcaa tatttcgttc
    11881 ttcttcatca ttatagtaga tcactggacg ataagaatca ccgcgatcag cgaactgtcc
    11941 taatgcgtca gtcggatcgg tttgctgcca atagatttcc accaactgat cataagaaat
    12001 aacttctgga tcatattcga tctctactgc ttctgtatgc cctgttgtgc ctgttgttac
    12061 ttgttcataa gttggatttg gtacatgccc gccagtataa ccggatgtca cagaaatgat
    12121 ccctggctgc tcttcaaatg gtttgaccat acaccaaaag catccgcctg cgaaaactgc
    12181 tttttttgtc atataaaatc cccctttttt ctcatcatac cttgatttcc aaaaggagga
    12241 taacgttttg cttgtgacag aaaaaacgga aactattata tacgtgatac ggcttctgat
    12301 aaatgccaaa acgaacgtac ttgatcaaaa acggttaaat caggaatcac atattcagca
    12361 gaaggaagat ttatgttttc acctattccc aatacatgca tgttaccagc caaagctgct
    12421 tgacaaccag cttctgaatc ttcaatgacc aagcatgcat ttggcggtac attcaattgc
    12481 tgtgctcctt tgagaaaaac ttctggatca ggttttgctt ttgatacttg cgtgccgtca
    12541 ataaggacat caaaataact tgtcaaattc gttttttcta aaatgaggcg tgcatttttg
    12601 cttgctgatc ccaatccgat cttgatgttt gtttttttca agtactcaag aacagctatt
    12661 gcaccaggca aaacggatgt ttcatccatt ttttgaatcg cttgaagata tagattgttt
    12721 ttttgctcag caaaggctga tttctctttt tctgagaatt tctgttccat ttttccaaat
    12781 gacagcaatc gctctagtga ctcggttctg gatattcctt tcagttgctc gttttctttc
    12841 tcagtgaatg gaatggacag ctggttagct aaaaccagcc acgcttcgta atgataacga
    12901 gctgtgtcta caagaacgcc atctaaatcg aatagtgctg ctttgatttt catcgattac
    12961 ctccttgaaa atgaacgact tgaagtaaag atgcgatgtt tttagctgtg cgatgaagat
    13021 tatcagtggc ttgctgtaaa gcttcttgta aaggcacagc tgcaggaagg atcggaaaaa
    13081 cggccgaaat gccaacatct gctgcttttt cgcttccttt accaacactt ccgcaaatag
    13141 ctatcacagg aacgccctct ggtactcttc tagcaatccc aactggcgct tttcctttta
    13201 gactttgtcc atctagacgt ccttcgccta cgattacgag gtctgcttgc tgtacccgtt
    13261 tatcgaactc cagtaaatcc aatacgtagt cgatgccaga gactattttc cctgaagcaa
    13321 atgctaacag tcctgcaccc attccaccac cagcactact gcccgatgcc tcgattactt
    13381 gaggggcaaa tctcatataa aaatcatgca tggcttggtc agccactgct aattcatttt
    13441 ctttcaagcc tttttgtggt ccgaaaacaa aagaagcgcc ttcttttccg cataaaagat
    13501 tagtaacatc agtaatgaca gtgattttgg ctttaatcag ctcaataggc acgttcgttt
    13561 tatcaactgt agcaatttta cctagatttt ctcccagtgc ttctactttt tgattatctt
    13621 gatcgtaaaa agcataacct agaccttctg ccatgccgat gccgccatcg ttggtactac
    13681 ttccgccaac gccgatgatg atgtgtcgaa caccttgttg caacaattgt cgtatcagtt
    13741 ctcctactcc tcgcgtggat aacctaagtg gctgttgttg gtttagtggg acatctttca
    13801 atccgacgat ttctgccatt tcaaaaatcg cagtttgacc gtctgaagcg tactggattt
    13861 ctttgttttt gccaaatgca ttagtaacga ctgctgtttg ccgcttcaac cttaaactgt
    13921 ctgctaatga tgaaaccgtt ccttctcctc catcgcctat aggtagcaga tcatattcag
    13981 cctgaacaaa aacttcttga aaacctgatt gaatggcttg tgctgcctct aaggctgtca
    14041 gactttcttt gaaagaatct ggcgcaatca gaatacgcat tattttcccc tccgttccaa
    14101 gatcagttct ttttccagct ggtattggtc tccattgaca aaaataggta atgtttcttt
    14161 cgtctctttt tttattacta tttgtttttt tgtcaaaaca aatagcaacc tgtgattttt
    14221 ccaaataaaa ggaaaagaaa ttttttccca tgctgaagga agtcttggag aaatagaaag
    14281 agttccattc gttactgtaa tacctgaaaa accaaatata actgctagcc atagtgctcc
    14341 taatgaagca gcatgaattc cgtcatctga tgaatgcgga tctggtccta aatcaatcag
    14401 gcacgcttct tggaataaat gatacgccca ttccatttct tggatacggc aagcctctat
    14461 ggcgtgaatc gctttactca acgatgagtc gtggattgtt ttgttttcat agtaatgcaa
    14521 attcttagaa acgattggtt gagaaaaata ctcaggtaat aagtataaca gcatgacaag
    14581 atctgcttgc ttgctgactt ggagttcatt tacttcgcta cgggcataat caagtaaaat
    14641 agactggctg ccaggacgtt ctttgtaagt ggtcaaatca ataactggct tactgagata
    14701 cgtgtcatct tgcggaatca gctgttcttt gttaggcact ggcaaatata acttatctaa
    14761 aaaattttga cattctttca aaaaaagcgg atcgccagct tgatatttaa cagctaaggc
    14821 cacattataa tgcgccagat agttcgtata tgcattattg tcgatatatt ctgtgtattc
    14881 atctggacca atgactctgt gtatctctaa atgatcatcg acttttacag ctctgctcag
    14941 ccaaaaagct gctgtttcat gaatgagcgt ttttcccttt gtttctaaaa acgattgatc
    15001 ctctgttgct tggacatact cttgaacggc ataagcaagg tctgcactga tatgatgttc
    15061 tgcggcagct gaagcaactt cttgtcttgt tccggttttg atattcaatg cagcaaattt
    15121 gggtgtctct tcctgaccag tgtgtgcgct ttcccatggg aaaagtgcac cttgatagtg
    15181 ataatctctt gctttttgcc gtgcgccttc taatcgatca taacggtaca gcagcaaatt
    15241 ctttgctact tcaggaaact gatataaaaa gaaaggcagg ataaaaattt ccgtatccca
    15301 gaaaacatgc cctttataac cttcgccagt tagtcccttc gcccctacac taacacttgg
    15361 atcattgcgg ggagtcataa tctgtaaatg gtaagcagcg aagtccatcg ctaactgatc
    15421 gaaagaagaa tcgccttgga tcgttatccg atgctgatgc caaaaatctg tccaataaga
    15481 catcgactgc tctaaaattt ctgtataact aacgcttttc tgggcttggg caatactttt
    15541 cttaaacggg tctgtttgct gaagagaggt agagagcacg atgatcttct ccagcgtaaa
    15601 ggacgtattt tttctgatct tttctgaaaa ggaagcggtg atccggcgat tttttgcttg
    15661 gaatacacct gctttattga atttagctgc aatcccaata tcaattttac tttctgttgt
    15721 ctggtaggat gcactgatca aatcgtcacc aaatactcgc agttcttttt caaccaactg
    15781 ctgtgtacca aaattggttt gctgtccatc gatacccgtt ttcacatcta cttggcagtc
    15841 ttcggtcaac ggcttgatga ccactttcag ggctgcctga tggagattat tttgatcagc
    15901 aacacgacaa gtaatgactt ccactttttt tccttgagca gtttcaatga gcgcatagcg
    15961 tttaagctct cccatttcta aatctagtgc ccgctcgtat gcaagaactt tcatcgtctc
    16021 aagagaaaaa tgttcaccgt cgatttttat ttcccatctg atgacatctg ggagattcac
    16081 taactcggct gattctgctc ctaaaggtcg gttatataca ccagctgcaa acattcccct
    16141 tacttgattc cgatagtctt cctcctggct tcctctgata ccaaaaaatc catttccaat
    16201 ggtcatctga ctcgcatact tattgatata ctctaaatca aactgttttt cttctacttt
    16261 cataaggtaa taacttctcc tgtttctgcc gaacgatata aattttccac cagattctgg
    16321 atgacatatc cttgccagcc atctgcaatc atctgagtct ggtcaccgag cgcccgattc
    16381 acaaaatgag ccatacttag ttcatgtggg tcattaactg gcgtggtctt ttgtaaggaa
    16441 accagctttc catctacatc ttcgaatagt tcgcctggat acagattagc acctgcctga
    16501 tcgccacaaa aagccacatt cagtttgtct tctctgatat tcaaagcaaa cgaagtattc
    16561 agttggatga tcttgccgtt ttctaattcc agtgtgccaa aaattgcatc ttctactgtg
    16621 aatttgcttg gatcccattt cccgaatttc cctgaatttt ttttcgtacc aattttttgg
    16681 aagctgtacg cccgaacgct ttttacttta ggaaatccag taatatacat cgctgtatca
    16741 agcatgtgaa tgccataatc gatcaaaggc ccgcctcctt gaagttcttt gtcgataaac
    16801 gttccccagc ctggaacacc agaccgacga agcgcattcg cttctacgta ataaatatcc
    16861 ccgagaacat caagatgatt cttgatcatt gttgcttcgt cagaaaaacg atgctggaat
    16921 ccataagcca aaatctgccc gtttttatcg gctgtctctg ccatctttct tgcttgatca
    16981 gctgtcatag ctggtggttt ctcgcacatc actgaagcat tagcttcgag ggcagccaat
    17041 acatgttcga agtgaaagcg attgggtgta cagacactca cgatatcggg agaaatctca
    17101 ttcagcattt gtgtaactga tgtatacgca tgagaaaatc ctgtacgtcg gcaaaagtct
    17161 tctgctcgct ggctgactgg atcaaccaca gcggccaatt ctaagacatc tgatcttttt
    17221 tgataataag cagcatgtac tttttctgct acttgtccag cgcctatgat tgctactttc
    17281 ttcatttatt tctccctcct ttgcttattt acttattgtt attctttctc tattctttct
    17341 ctaaatcatt taaatgacgc gctgtttcca gacagttttt caagtattgc aatgattcct
    17401 gataaatttt cacttcattt tctcctcgca aacgacattc atataccata taaccttcat
    17461 actcattttg aagtagcgtt tgaaaatggc gagtaaaatc aattgcgcca gatcctggtt
    17521 ggtagcgatg attatctgct aaatggatat gacccacata ctctttttgc gtagtcaatg
    17581 cttttgaaat atcatcttct tcaatattca tatgataaaa atcagcgatg atctgcacat
    17641 gtttcaattg attagagtca atgtaatgac gcgcatccgc taacaaattg atcatatggt
    17701 cttggtatcg gttcaaaggc tccaaataaa taaccgtacc tgtttcttcg gctactttat
    17761 ctaaataacg aagtgattcg ctgactgctt tatagtctcc ttctttgctt cggggtgaaa
    17821 ccatcggcgg taatcgataa gtgaacattc cccaagctgc tgggataacg attcctttgc
    17881 ctccaacctc gcttagtgca cgcaaaatct cagcaatttg acgtacacca ttaagacgcc
    17941 gttcttcgat aaagtcaccg atccacccat cgtagccgtt acaagctgtc actactggga
    18001 tccctgtttc tttgattgcc tgtttgactg tgtcgatatt ttctattaac aacttaccgt
    18061 cgatttcgta ttcttcaaat ccacagtctt tgataaatct aaatttttct aaaatgtctc
    18121 ttgggaaaaa tgcttgatct tgcgtaccga atttcattgt tctcctcctc ggacttgaac
    18181 gcccattttg atactttctt ctgggtgctg gtctacataa cgcatgtaag cttctgcgct
    18241 ttctgcaaat ggcacaactg gatcaatgat ttcttcacaa tccaagtaac cgttcatcaa
    18301 taattcccaa catgtgtcct cgattcgttt acggttccat cttgggtaat ctgggtttgg
    18361 ttcactagat gctcgagcaa agacgatttt tgcattattg aaatgtgctt cgcgaccaag
    18421 attaaaccca gctggaaaag gtttagcaaa ggcaacataa gaaatgatcc cgccatagcc
    18481 gatccctctt aaagaagctt gtaatgcggc agcactgcca ctcgtttcaa taactgaatc
    18541 tactccacgt ttatctgtca attcctttag acgaaaaccg acatctgctt tcataggatc
    18601 tagcgtgtaa tcggcaccgt atttttctgc taattctcta cgctgcgcta tgggatcgat
    18661 cccaacgatg gtagtagcac ctgctttttt agctaattga atcgcaattt gcccgatagc
    18721 gcctaaaccg aagattgcta cagcatcacc tgctcgaaca tgtgcttccc ggataccacc
    18781 taaagcgaat tgagcaggat cgtaacatac tgcatttttc cattgatcca accgatcaag
    18841 tttacgtagt ttataattat caacaccgtt tgtaatcagc gtttcacgaa tgggtccata
    18901 agtgcagact aactctcctt tttgatactc tgtcaccaaa ctgcccgttt cttcgatcgt
    18961 accgacaatc atatttccta attgaaattc gccaaatacc acaccgcgtt ggcttccttc
    19021 ttctcttggc aagaataggc gccattcttc tgaaaattct tcatcgataa atggacttaa
    19081 tcctctaaag tcgacaattt ctgttcctgg ttttggagta gcgaaaatta ctcggatacg
    19141 tacttcgttc ttttcgatct cacggtcttc gtaatctttg aatccggcta ttcttggttc
    19201 taatgcaact aattttttca tcttttcttt cctctttctt ttctttttat ccttttacgc
    19261 cgccttcgac taaatcacct ttaataaatc gttcagataa cgcatacata atgatgactg
    19321 gtaaagcggt caccaatgaa gcggccatca ttcgtcccca aatgtagtct ggtgtactga
    19381 ataatgtgtt caaaccgatt ggtaaagtaa atttttcgga ggtcgacagg aaaatcgaag
    19441 caaataaata atcattccac gaaaccataa agcaataaac gaagacagaa atgattccag
    19501 aaatagccaa tggtataatg atccgaataa tgatctggat ccggctaaga ccatcgatca
    19561 ttgctgcttc ttcaatatca gtcggaatcg tgtcaaaata actttttagc atgaatatcg
    19621 cagtaggaag tgtttgaacg accatcgtga taatcagtgc tgtattggta tcatacaaac
    19681 ctagaccgga aatgatttta aataatggaa caacgatcaa aataccggaa aacatataaa
    19741 cggtgtaaaa gctagcattg attttcgagc gagctttgaa gcgtagtttt gacaaagcgt
    19801 atgccccgct gatcccaatc actactgcag ttacggaggc tatcaaggag atcactaaac
    19861 tatttttgaa atacatgatg aatggaaaaa tctcagcatt gaaaatatcc tgataatgtt
    19921 caaaagtcca ttctttcgga aaaatagttt gtgtcgttgc aattgcttct tgtgaatcct
    19981 tgaatgatgt catcagcatg atcaaaaatg gaaacaaatt gacagctaat agcaacaaaa
    20041 tcgtcgcgta aaataagatt ttcctgctct ttttattttt catttcaagt ccaccttctt
    20101 tcgtgagagc aagacgaccg ctgcaataat gatgaacaat agaatcgata tagctgctgc
    20161 ttttccaaga tcattgaacg caaaggctgt ctgatacaaa taaacgccta agatattgac
    20221 tttattcgtc agtagataga catctgtaaa catatagaac atccagatag atcgtaaaac
    20281 aatcacagtt gctagtactg gtttgattgc cggcagtgtc acgatcttga acttctgcca
    20341 agcatttgca ccgtccattt cagctgcttc ataaagcgtt ttgtcgactg tttgcaaaat
    20401 agccaaaaat gaaataaacg catacggata gtatctccag atagcaaaca aaacgaccat
    20461 aaagaagcta gcaactggct ggtcgaacca cagcggtgct tcgttgaaaa gctgcaacct
    20521 atctactaac agatcattga cgattccata actattattg aacatatatt tccaagcaaa
    20581 aatcaaagaa atagatggcg taacataact taataaaatc agtgaacgca ccgttttcct
    20641 aaatctgaac ttgcggttaa gcaaaatagc tacggctaat cctaaagctg tactgcctgc
    20701 tacaactaag aatgtgtaag caactgttaa acctaaagaa cgataaaatt cactatcact
    20761 taaaatttca agataattgc ttaatccgat aaaaacggcg tctgagttag gattcagcgg
    20821 catatcgaaa aaactgatct gaatattgga aagcattgga atcagcacta aaacagctaa
    20881 taaaagcatg cttggtgcta aaagtcccat ggctaatttt aagtcagaat gtttccttgg
    20941 acgattcatt gaaacctccc cctgataatc tgccaatagc tatctacttt tttcgaacac
    21001 cattggcaga acttcttgtt atttcgtatt tttttgtgcg tcagctaaag cttgatcgac
    21061 atcttcgttt ccgacagtta cttggttcac tgcttttccg atcacacctg agcttgtgat
    21121 atctcccatt ttcgtgaaat tcttttcccc gactagtcca aagacttgta cttcatcaaa
    21181 agcactagca atctcagatg gcagctcgcc aaaagacttg atgacttcat tttctttgta
    21241 accatccagt tcgactactt gtttattcac tggttgagca ccaccaggag acatcaagac
    21301 ccacttttcc atgtttttcg gttgagataa gaaagctgtg aatgcttcag cagcctcttt
    21361 ttgtttctcg tctagaccag aagaaatcgt caatccagat actgtgccat agacagcttg
    21421 atctttttgt gttgggatag caaaaccgat attttctgag ttccccgctt cataaacaga
    21481 aggcaaaatg taagttgaat agattgccat tggtgctgtt ccattcatga aagcatcttt
    21541 gatttctgtc acatcattag agcctggcat cgtgtattgg gataagtttt gataaaacga
    21601 caatgcttct ctcatctttt ccgtatcgat cgttacctcg ccttcatcat ccaaaacatt
    21661 tgctccattt gacaaagcaa attgagagaa cgcttgctca ctcattgttc cttcagcagt
    21721 aggcatagca attccatatt gtttattctc tttatctgtg aaatgttgag caatttttaa
    21781 aatatcatcc caattttctg gttctgaaaa accagcttct gataattttt ctttgtcata
    21841 ccaaatacct tgaacccagc cgctaattgg tgcagcaata tagctttttc catcttctga
    21901 acgaacaagg tttttggctc cgtcataata attatcttct ccagcttcct cgataacgtt
    21961 ttggactgcc gtctgatcaa tcagttcatc tttatccatc actttagcaa aatcctgact
    22021 gacttccatt acttctggta atttaccgga acgagctaac gtaacgattt ttgtattgaa
    22081 cgctgattct tctaccggca cttgcttgat tttgatgtct ggattttctt tttcaaaatc
    22141 agcaaccagt tcattgatca cacttaatcg ttcctgttcg acagaagagt gcatgaattg
    22201 aatcgttgtc tgttgtgatt cgttagagct ttgactttca ccacaagcag taagaagaaa
    22261 tccagtagct agcagacagg tagtaacaat aatttttttc atttttttcc acctcttatt
    22321 ttattatttt cagccacata tattcatacg gctggaatat caactttcgt tcttgactgc
    22381 aatggataat ttgtccagaa aacaggtcta ggtaatctcc ttttggtaaa agataacctg
    22441 ctgattgatt ggaaaaatta tggataacta agactttctc ttccttcgct tcgcgaataa
    22501 aactgataaa agaatctgct gagtccagta agtaaatcaa actattcgga tggaaggctt
    22561 tttctttttt tcgaatagat agcatctggg tcaattcacc atatactgct gttcttaatg
    22621 gatctgtctg caactctttc tcaatatctg ctaacaaaaa tttttgccga ttgatttttc
    22681 gattctctcc tgttttttct acgcctttgt aatcatttcg acttcccagc acactttgaa
    22741 tataaattgc cggcacgcct ggtaacgtta ccaaaaatga atgagcagct aaaaagcgtt
    22801 tgcttctcca ttccgtcgta tctgttggag aacttaacgc atctagatac gtagcgttta
    22861 tctcatatgg actggtcgtt ccatctgggt ttttcttgta gtttactcgg gcaccctctt
    22921 tcttcagctg ttccactaat tcaaggatcg ttttttccgg cagaatacct cgtaccggat
    22981 tcaatccgat accgtcatgg gaggctaaaa aattaaaaaa agttgttttt ttcgatgcga
    23041 aatcgatggt ttttaaccat tctttcaact tacttgtatt acccgaacga atcgcttgaa
    23101 gggtcaaagg tggtagcgaa aactgataga ccatctgtgc ttcattctcg ccattcccaa
    23161 aataactgat attatctttg tgtggcacat ttgtctcagt gatcaatacc gttcctggag
    23221 ctgcttcatc agcgattgca cggaataatt ggatgatttt atgcgtttct ggcaggtgta
    23281 tacaagaagt tcctagttct ttccataaaa atcccacagc gtccaagcga ataaatgaag
    23341 cgcctttttc taagtaaaac aaaagaatat cgatcatttt caataaaact tctggatttt
    23401 taaaattcaa gtctacttga tcttcgctaa aagtcgtcca tacgtgtttt tctttcccgt
    23461 ttttgtcaat gaacgttgta agtaacgggc tggtccttgg tctagtcacg ctgcttgtat
    23521 ctgtatccag tggcaaatca ataaaaaaat ctttgtacgt atcattcaag tttaaatatt
    23581 cctgaaacca agtactttcg gcagacatat gattgcagac aaagtcgaac attaaccgtg
    23641 tttcgcttct catttcttct atatcttccc atgtgcccaa acggtcgttg attgcctgat
    23701 aatttacaac ggagaaacca tcatcagatg tatatgggaa aaatggcaag aaatgtacaa
    23761 ctctaaatgt atctgccaaa tacttttgat aaaatttctt aaatgtacgc aaagttggtt
    23821 gctgctcttc aaaaaattga tccccataag taatcaagaa aatatcttct tcgtcccaat
    23881 gcagtttgcc tgcctggcct ttcttctgct gataaacact gactttttgt tcaatcatag
    23941 aggcggtttt ctcagacaaa tctgagtcgc gataaatcgc ttgtaaaagt tttgtataca
    24001 tcggattccc ctttcttttt tgggagcgtt cccaacgatt tgatcatatt atggaaaacg
    24061 cttactgtca atagcatttt tttaaataat tttgatatac acaaaaatac aaataagaaa
    24121 gcttatgtat caataattaa tagcttctta aaaaaatatg gtctctcatg atcatgcaag
    24181 ctattcctaa attttcaaaa tcatagacaa aaaagaatgt ctattgtact atggaattat
    24241 tctaaaacgc tcccaaaaag gaggtgcata taaaattgaa acctactatt tatgacattg
    24301 cgaaaaaagc taatgtctca aaatcaactg tctccagagt attaaataac cagccaaata
    24361 tctctgataa agcaaaagca agtgtacttc aagcaatcaa agaattgaat tatgaaccga
    24421 gcaaaattgc aagaggactg tcaggaaatg gttttgacgc gattctagca ttatctcatc
    24481 gtacttctca tacgacctat ggcaatcctt ttttttcaga tgttattcaa tccatttctg
    24541 ccgtttctga acaaaataac ttcgacttga ttctacaaac ggcaaaaaca ccagaagaag
    24601 agctagaaaa atgcgcgaaa aagatccaag aaaaaatgat ccgaggaatt attattttaa
    24661 gctctacgat ggatgaaaca cttctttttg aattggatca atacaatatt cctattgtgg
    24721 taatcggaaa agtcggaaac gactacacga acatctactc agtggacacg gataatttcc
    24781 aggatagtta cgatttggtg gaaacactga tcaagaatgg acaccgtcat atcggctgtc
    24841 tccatgctcc gacagaagtt tatgtatcca atgatcgtct caatggttac cgtcaatgct
    24901 tatttgatca ccacctagat atccgtaatg aatggattat agacggcggc tttcgcttag
    24961 aagatagcat ggcagcaatg aatgatttaa tgaagctacg agaaagacca actgcgattt
    25021 tttctaccga tgcattaaaa tcattgagta tttacaaagt ggcagaacaa tctggaaagc
    25081 agatacctga tgatctttcg atcgcaggat tcagtgatcc cttattgtcc tccctatttt
    25141 cgccacagtt gactcggata gacattccga caaatcagtt aggaatcaaa gccacagaac
    25201 ttttattcca actaatccac caccaatacc ctgaagaaaa aagaatcatt ctttcaaccg
    25261 agattactct cacagattcg atccaacaac aagaaatgta gaacagaatt ataaaagaac
    25321 agaaacactg aggataagtc agttactctg ttcttttttc aatcactcat ccctcgttac
    25381 cccctcccgg tattttagcg aatttttctt attttccatc tgttttagat agctgtggat
    25441 aactataatg tttgtgttaa actatttttt ccacagggaa gaaaaaacta tttttaacca
    25501 cgttgtgtat aagtttttat agttcgtttt tttaaacaca tttaccctta tttcaatcca
    25561 tgttatttgg ggatacttat ctctaaaaca taaatagaat aacagacatg tctactggtt
    25621 ttgttttatt cgaggaatta ttcaataata gctagcaaaa tattaaaaat aaccgctcta
    25681 tcttcccatc aatttatttt gcattcaaaa aatgatctat ctttactttt gttgattgac
    25741 ttctcttgga agatgatcgt tccgatacct taattggata cgaaccgatg ttgttaagat
    25801 cctttcccac ttttcttcta gttagacaaa ttattttaga caaaccaaaa aagaggttgt
    25861 gacaataatt tgtcacaacc tcttttttaa aatatctatt ttgtttgatt gttcattgcg
    25921 tcttctgcag ccatttgcgc ttcaatatct gaaatactgt agacattttc gcttgctaca
    25981 ccgacttctt ttggttccat gtcacgataa cgttgcatac cagtaccagc tgggatgatc
    26041 ttacctataa taacattttc tttcaaacca agaagaggat ctttcttacc gcggatcgca
    26101 gcatccgtca agacacgagt tgtttcttgg aatgatgcag cagataagaa actatttgtt
    26161 tctaatgatg cttttgtgat acctagtaag acaggtcgag aagttgcagg aacgcctcct
    26221 gagactagcg tattgtagtt ttgatcttta aagtctgcga tgtctaataa tgtacctggt
    26281 aagatatctg tatcacctgg atccattaca cgaactttac gcagcatttg acgaaccatt
    26341 acttcgatat gcttgtcgcc gatttctacc ccttgcatac ggtaaacacg ttgtacttca
    26401 cgaagcaagt agttttcaac agataataca tcgcgaactt gcaacaattg ttttggatcg
    26461 attgatcctt ctgtcaatgg tgcaccacgg tggatcatat cgccttctgc tactttcata
    26521 cgtgctgtat aaggaacagt atacgtacgt gtatctgttt ttcctttgat tgttacttct
    26581 ttggtacgtg ttgcaggatc ttctgagata tcgatgacat cccctgttac ttctgtgatc
    26641 actgcttgcc ctttcggatt acgtgcttca aagatttctt ggacacgagg aagaccttga
    26701 gtgatatcgt ctccggcaac cccacctgta tggaatgtac gcatcgtcaa ctgagtacca
    26761 ggttcaccga ttgattgagc ggcgatcgta ccaactgctt ctccgacttc aacgtcagag
    26821 ccagttgcaa ggttgcgtcc gtaacaatgt ttgcagacac catgttttgt attacatgtg
    26881 aagacagaac ggattgtcac tgtttcgaca cctgcatcaa cgatttgttt tgcgatgtct
    26941 tcggaaatca attggtttcc tgcaatgatc aattcatttg tttcaggatg acgtacttct
    27001 ttacgggtgt aacgtcccac taaacgatct tctaatgatt cgatgatttc atttccctcg
    27061 cggatggctt ggatttcaag acctcggtca gtaccgcaat cttcttcacg gatgattaca
    27121 tcttgggcca cgtcaaccag acgacgagtc aagtaacctg aatcggcagt cttcaaggct
    27181 gtatcggtca tccctttacg agccccgtga gttgagataa acatttccaa gacggatagt
    27241 ccttcacgga agttcgaaat gattggcaat tccatgattc gaccattagg agcggccatc
    27301 aaaccacgca ttccggcaag ctgtgtaaag ttggaaatgt taccacgagc tccagaatca
    27361 gacatcatga agattggatt tttcgcttcc aaaccttcca tcagtttttg ttggatgctg
    27421 tcttttgcag cattccaaac agcaatgaca cgttcataac gttcgtcatc tgtgatcaga
    27481 ccacgacgga attgttttgt aatagtttca acttgtttat gggcattttc aatgatttct
    27541 tgtttttcat tcagtacact gatgtcagcg atccctactg tgataccggc atgtgtcgaa
    27601 tgtttgtacc ctaagtcttt catacggtca agcatcttag aagtttcttt tactttgaat
    27661 cgtttgaaga cttctgcgat gatgtttcct aagtttttct tcttgaacgg taatactaat
    27721 tcttgctctt tgatatgtgc aggaatatca gtaccagctt caacaaagta tttgtccggt
    27781 gtttggacgg tcaagttgaa gtctgttggt tcattcagat aagggaattc aggaggcatg
    27841 atctcgttga agatgatctt accaactgtt gtgatcatcg tacgttcttt ttgccattca
    27901 gtaaatggtt tttcacctaa tgagttaggg ttcacaccga tacgtgaatg taaatgaaca
    27961 tatccgttgc gccatgcgat aacggcttcg ttttgatctc tgaagaccat tccttcgcct
    28021 tcgcgtcctt cttcttccat tgtcaagtag tagttaccta gaaccatatc ttgagaagga
    28081 gtaacaactg gtttaccatc tttagggttc aagatgtttt gagcagctaa catcaacata
    28141 cgtgcttctg cttgtgcttc ttcattcaat ggaacgtgga cagccatttg gtctccatcg
    28201 aaatcggcat tataagcttc acatacaagt ggatgcaaac ggattgcgcg tccttgtact
    28261 aaaactggtt cgaatgcttg gataccaagt cggtgaagcg taggtgcccg gttcagcaat
    28321 actgggtgtt ccttgattac gtcttctaaa acatcccata cttcgtcttc ttgacgttcg
    28381 attttacgtt tcgcattttt gatgtttgaa gctagttcgc gttgaacaag ctcacgcatc
    28441 acgaatggtt tgaataattc aatggccatt tcttttggaa gtccacattg gtacatcttc
    28501 aagaaaggtc caacaacgat aacggaacga cctgagtagt cgacacgttt acctagcaag
    28561 ttttgacgga aacgaccttg tttccctttc aacatatgag aaagagattt caatgggcgg
    28621 ttacctggtc cagtaactgg acgtccgcga cgaccgttat cgatcaatgc atctactgct
    28681 tcttgcagca tacgtttttc attttgaacg atgattccag gtgcattcaa gtctaacaaa
    28741 cgtttcaaac ggttattacg gttgattaca cgacggtaaa gatcattcaa gtcacttgtt
    28801 gcaaaacgtc caccttctaa ttgaaccatt gggcgtaaat ctggtggaat aacagggata
    28861 acgtccataa ccatccagct tggttgattt cctgaagcgc ggaatgcttc taaaatatcc
    28921 aaacggcgga ttgcacgtgt acgtttttgt ccttgtgcag atttcaattc ttctttcaat
    28981 tcggctgctt ctgcatctag atcaacatta tcaagtaatt gtttaatcgc ttctgcaccc
    29041 atagcagctt ggaattcttg tccatattgt tcacgttttt cgcgatattc gcgttctgtc
    29101 aacaattgtt ttttctctaa attcgtattt cctggttcga tgactacata tgaagcaaaa
    29161 taaatgattt cttccaaagc gcgtgggctc atgtctaata caagacccat acgtgaagga
    29221 atccctttaa agtaccagat atgtgaaaca ggagctgcta attcaatatg tcccatgcgt
    29281 tcacggcgaa ctttcgaacg agtaacttcc actccgcatc gatcacaaac gattccttta
    29341 taacggatac gtttgtattt tccgcaggca cattcccagt cttttgtagg accaaaaatc
    29401 cgctcacaga acaacccttc gcgttcaggt tttaaggtac gatagttaat cgtctcaggt
    29461 ttttttactt caccgtaaga ccagcttctg attttttcgg gagaagccaa acctatttgc
    29521 atactttcga atttatttac atcgatcaaa aggggttccc tccatttcat ttaatggcaa
    29581 accgcaagac ggctgatctt cgaccgcctt gcagctcata gaccggatta gtctaaatta
    29641 tcttctgcgg tttcaaagtt ttggatgaca tcgtcttttt catcttccac ttgttcagca
    29701 gctttctttt ctaattcttt ggcagtttgc tgttcggcaa attttgtcaa agcatcaaca
    29761 gtgatcaaat cgtcgtcttc atcgtccatg tcgcgaagtt cgatctctgt ttcttcgata
    29821 tccaagacac gcatgtccag acctagtgat tgcaattctt tcaccaatac gcggaatgat
    29881 tccggtacac ctggttttgg aattggttca cccttgacga ttgcttcgta tgttttcaca
    29941 cgtccgacta cgtcatctga tttgtatgtc aagatttctt gtaaagtata agccgcaccg
    30001 taagcttcca gtgcccatac ttccatttca ccaaaacgtt gtccaccaaa ttgagcttta
    30061 cctcccaatg gttgttgtgt aaccaatgag taaggtccga ttgaacgtgc atgcaatttg
    30121 tcatcgacca tgtgagcaag tttgatcatg tacatcacac cgacagacac acgtccatca
    30181 aatggttcac ctgtacgtcc gtcgtacaga acagttttcg catcgctggc cataccggct
    30241 tcacgaactg tttcccatac gtcttcatca cttgcaccat caaatactgg cgttgctacg
    30301 tggataccta actgacgtgc agccataccc aagtgtaatt ccaatacttg cccgatgttc
    30361 atacgtgaag gcacccctaa aggattcagc atgatatcga ttggtgttcc atcaggtagg
    30421 aatggcatat cttcttccgg cataatacgg gatacaaccc ctttatttcc gtgacgaccg
    30481 gccattttat ccccttcatg gattttacgt ttttgaacga tataaacacg aactaacatg
    30541 tttacgcctg gtgacaattc atctccagct tcacgagtaa agattttcac atcgtgaacg
    30601 ataccgccgc cgccatgtgg tacacgtaat gatgtatcgc ggacttcacg agctttttcg
    30661 ccaaagatcg catgcaatag acgttcttct gcagataatt ctgttacccc ttttggcgtg
    30721 actttcccta caagcaaatc gccatcttgg acttctgcac caatacggat gatacccatt
    30781 tcgtctaaat cttttaatgc gtcttccccg acattaggga tttcgcgtgt gatttcttca
    30841 ggtcctaatt ttgtatcgcg ggcttctgat tcatattctt caatatggat agaagtgtat
    30901 acgtcatctt ttaccaaacg acggctcatg atgatcgcat cttcatagtt gtacccttcc
    30961 caagtcatga aaccaactaa aacgttttgg cctagagcca tttcgccttg ttccatagat
    31021 ggtccgtctg ccagagtatc ccctttttcg actttctcac ccaaatgaac gattggacgt
    31081 tggttgtagc ttgttccgga gtttgaacga cggaattttg ttacatcgta tttatctaat
    31141 gcaccgttgt cgcggcgtac gcggatttca gaagcatcaa cgtattcaac gacaccatca
    31201 tgtttacata acaaagcagc tcctgagtca tgcgctgatt tgtattccat accagtacca
    31261 acccatggtg cttgaggatt gatcaacggc actgcttgac gctgcatgtt ggcacccatc
    31321 aaggcacggt tggagtcatc gttttccaag aaaggaatac atgctgtcgc aacggcaact
    31381 acttgtttag gtgatacgtc catgtagtct actttatcaa tagatacttc taagttttca
    31441 ctttgagcac gagccataac aacgtcttga gcaaatgttc catcttcatt caatgggctg
    31501 tttgcttggg ctacgatgta atggtcttcg atatcagctg tcaagtagtc gatttggtca
    31561 gtaacacgac ctgtttcacg gtctacacga cgataaggtg tttcgataaa tccgaattta
    31621 tttactttcg cataactgga caaactattg atcaacccga tgtttgggcc ttcaggagtt
    31681 tcgatcggac acatacggcc atagtgggag tagtgaacgt cacgaacttc ataaccggcg
    31741 cggtcacgag tcaatccgcc aggtcctaag gcgaaaagac gacgtttgtg tgtcaattcg
    31801 ccaagagggt ttgtttgatc catgaactgt gacaactgag aagaaccaaa gaattctttg
    31861 atacttgcca caactggacg gatattgatc aattgttgag gtgtcaatgt ttcagtatct
    31921 tggatcgaca ttctttcacg aaccacacgt tccatacgtg ctagcccgat acggaattgg
    31981 ttttgtaaaa gttcaccgac tgaacggata cgacgatttc ctaagtggtc gatatcatcg
    32041 acattgccga taccttccat caagttcaag aaatagctca ttgaagcaat gatgtcggct
    32101 ggacgaaccg tttttacagc tgcttctgga tagccgtttc cgatcacgtt tacttcacgt
    32161 tcagggtctc ttggtgaaaa tactttgatg acttggacag tcattggatc tgtgaccaca
    32221 ccgtcttctg atggatagta agtcactgaa tttaggccat tatcaatgaa aggagctagt
    32281 gtttccatga cttggtgagt cagaactgtt cctttttcaa cgatgatctc gcctgtttct
    32341 ggatcaacta atgtttcagc taatgtcaga ttcaatagac gtgttttcaa atctaatttt
    32401 ttgtttactt tgtaacgacc aacgtttgct aagtcgtaac gttttggatc gaagaaacga
    32461 gcattcagca agttacgtga gctgtctgct gtttttggtt cgcctggacg caaacgttcg
    32521 taaacgtctt tcaaaccttc ttctgttctt gagtcgcttg cgtttttatg caagtctttt
    32581 tcgactgtat tgcgtaatgt ttcgctgtcg ccgaagattt caaagatcgt atcatcggaa
    32641 ccaaatccta acgcacgaac taatacggtt aaaggaatct tacgtgtacg gtcgatacgt
    32701 acataagaga tgtcttttgc atcagtttcc atttctagcc aagctccacg gttagggata
    32761 acagtagaac cgaatccttc ttttccgttt ttgtcgactt ttccatggaa atagacacct
    32821 ggtgaacgga ctaactgaga aacgattact cgctctgccc cgttgatgat gaatgttcct
    32881 tgttctgtca ttaatgggaa atcaccgaag aatacttctt gtgctttgat ttcgccagtc
    32941 tcgcggtttg tcaaacgcaa tgttacatgt aatggtgcag agtagtttgc atcatgcgca
    33001 cgagcttctg ctactgtata ctttggttct ttcaattcat aatctacaaa ttccaaagat
    33061 agattgccat tgaagtcatc gattggcaaa atgtcttcaa acatttctct aagtccctca
    33121 tctaagaacc attggtaaga gtctgtttga atttcgatca aatttggtaa ttccaacact
    33181 tcactgattc ttgcgaaact tctacgttcg cgatgttttc cgtattttac tacgtgtcca
    33241 gccaagctct tcacccctct aaaatgtcat tcaaaaagac tacccgatca attgttacaa
    33301 taatatttca aatattattt ttaggtaaca acagacattt tttgcggctt ttaggcaaaa
    33361 aaaaaccaaa aatagaacat tctcttgaaa ccttacttcg tgagcttcta cttttgtttc
    33421 cttatattaa agccgaaacg gacaatattt cgtttctgcc ttttcttcat cagatagttt
    33481 ttgcaacttc atatactaca cttattttct ataaaagtca acacttcctg gcgtttcttc
    33541 tgctttttcg caacattttc ttaatgtttt caattttatg ttttcaatta tctgacaatt
    33601 cttaattgac agaccttttt atctcggtta tactttagaa aattcatttt gtggaggaac
    33661 ttctatgcga accaacatca accaaatcgc accaacacaa ctgaataact tttactttag
    33721 ctactttaga taggtttgta ttcatcatga tggatacaaa cgttaaacga cagtttgtat
    33781 ctatgatggc taaagaactt tgtattgcag caaaaagcca cgtagacaaa atgctaagtg
    33841 gctgagcagt gaaaatacaa agtaaaagta tcaagcattc tactttttca atttattttc
    33901 cgacttttca atccatttgg acattttgtc tgaatggatt ttttgtttcc caaaattaag
    33961 gaggaaaaag aaatgaaaaa aaatataatc atcggattag gcgctgccct gctactagct
    34021 ttaggaggtt gcgcacaaaa agacaattcc gcagaggcat cagatggaca aaaaacaatt
    34081 ggcgtattgc aacttgtaca acataactcg ttagatgctg cctataaagg attcaaagaa
    34141 ggattagcag aagaagggta taaagaaggc gataatctaa caatcgatta tcaaaatgcc
    34201 caaaacaatc aagacaacct gaaaagtatg agtgagaaac tcgtcaaaga agatcctgat
    34261 ttgctacttg gaatcgccac tccagcagca caatctttat taaatgaaac aaccactatc
    34321 ccgatgactg tcacagcggt cacagacttg gaacaagccc atttagtcac atccaatgaa
    34381 aaacctggcg gcaatgtgac tggcacgaca gatatggtgc caatcgaaaa acaaatcggc
    34441 ttactgttaa atatcgtgcc agacgccaaa acaatcggca tcatgtataa caacggtgaa
    34501 gcaaactcta agatccaagc tgatttggca gaaaaagaat tgaaaaaagc gggcgtcaaa
    34561 gtcaaagtac tgacagcaaa ttccacaaat gatgtccaac aagtgacgaa aagtctagct
    34621 aaagatgtag atggaatcta tattcctact gataacacgt tcgcaagtgc ggcaagtgtt
    34681 gtcggtgaag tcgcaaaaga aacaaaaaca cctgtcgttg ctggcgcagt tgatcaagtc
    34741 aaagacggcg gtctagcaac agtaggaatc gactacgaaa gcttgggcaa acaaacaggg
    34801 atcatggcag caaaaatctt agacggcaag aatccaagtg aacttcctgt cgaaacagcg
    34861 aatgatttgg aactgtatgt caataaagac atggccaaag cattaggcat caatccagac
    34921 agcatcaaag aagctgaata aaacacagga ggattctcat gacaaatttg ctctctcttt
    34981 tcttatcatc tgcatcgcaa ggggtcttat gggccctact tgcgattggt gtatacgtca
    35041 ctttccgtat cttggacatt gccgacttga ctgctgaagg aagctttcct ttaggtgcag
    35101 ggatcgcggc agtaagtatt acaaatggct atcatccatt gacagcttgt cttctaggct
    35161 ttttagggag tgcggcagca gggcttgttt ccggactgct tcacacaaaa ttgaaaattc
    35221 ccgcccttct tgcagggatc atcaccatga ctggtttata ttctgtcaca tcccgtgtga
    35281 tgggtgcgcc gaacatctct ttattgggtc agccaacgat ctttcattgg gtcgagtcat
    35341 tcggcataac aaaagacaac gctgtactga tcgtcggtct gctttttgct ttgatcgttg
    35401 tatgtttact tgttttgttc ttacgtacag aaacaggact tgctattcgt gcaactggcg
    35461 ataatctggc aatgagcgaa gcaaacggga tcaacacaga taatatgaag atcatcggtt
    35521 atatgatttc taatggatgc attgctcttt ctggctcctt gcttgcgcaa aacaacggct
    35581 ttgctgattt aaattctggt attggaacga tcgtaattgg acttgcttct attatcatcg
    35641 cagaagtttt gttacgtaac cagccactat ttctccgtct cttgactgtc gttttaggtg
    35701 cggtcattta tcgttttatt ttagcgttag tcttcgaact gaatgttgaa ccaagtgatt
    35761 cgaaacttgc ttctgctttc gtgctagtga tctgtctttc tttcccgcag atccagcaaa
    35821 aattccattt acctcaaaaa aagaaaggcg gtagtgtcaa atgaatgacg tcttaacatt
    35881 ggaaaatctc catcatacct ttgaaaaagg aacgatcaac gaaaatcatg tcctgaaagg
    35941 cattaatctt tccttagatc ccggcgactt cgtgacgatc atcggtggaa atggggctgg
    36001 taaatctact ttgctgaaca gcatcgccgg tacattttct gtcgatcagg gtcaaatttt
    36061 attgaatgga aaaaatatca cgaaaaaatc tgttgtcgaa cgttcgaaat ccatcagtcg
    36121 cgtattccaa gatcctaaac tagggacagc cgttcgttta acggtagaag aaaatcttgc
    36181 tcttgctatg aaacgaggaa aaaaacgcgg cttcttccgt ggtgtcaaac cacaagaccg
    36241 aacatttttc aaagaccagc tggttcggct aaatttgggg ttggaaaatc gtttatcctc
    36301 agaaatcggt ttgctgtctg gaggacaacg tcaagctatt acgttattga tggccacatt
    36361 acagcgtcca gaactgatct tattagatga acacactgca gcgcttgacc ctgctacttc
    36421 caaaacggtg atggaattga cagaaaagct gatcactgag cagaatctca ctgcttttat
    36481 ggtcactcat gacatggaag acgcgatccg ctatgggagt cgactgatca tgctgcatca
    36541 aggaaggatc gtcgtagata tccagcaaga ggaaaaacag cagctcacag tgccccaatt
    36601 attagcgttg ttcaaacaaa acagcggcac ggcattaaaa gacgatcaag tacttttatc
    36661 ttcataatca gaaagaggat gggacaaaaa atgaacgccc accctcttct tttttctctt
    36721 tccttctttc gtttttgctt tatgtatcaa ccgttgtttc ttcgaaaact attttgttct
    36781 ctccttcttc ctgatagaat ggatgggaaa ggagcttgat gccatgacaa cgaaagacaa
    36841 ggtacttcaa ttattgaaaa agacaccaga ttttctttcc ggagaaaagt tggcacagca
    36901 actggaagtt tcccggacaa gtatttggaa agccatcaaa gaattggaaa aggcaggcta
    36961 tcgttttgag cacgggccta cagggtatcg ttacctgccc tctgacgtac tagatgcaaa
    37021 agaaatccag caagagctac ggtcgtttat tcctgatttg aaagtacaaa cgatgttgac
    37081 ttctgaatct acgatgaaag atgccaaact ggcagcagct caaggagatt ctgtttcgaa
    37141 gttatttgtt gctgatacac aagaacaagc tcgtggacgt tttggacggc cttttttcgc
    37201 tgaacctgga cgaggaatct acatgagtct cttgctccat ccagacaaac ggtttgatga
    37261 attgcctcaa tatacgatca tcgcagccag tgcctgtgtg aaagccattg aatctgtaac
    37321 cggtcgttct gcttcgatca aatgggtcaa tgatatctac atggatggaa aaaaagtctg
    37381 tgggatttta tctgaagcag tcagtgatat ggaaagcggc aggatcagtc atatcatcat
    37441 tgggatcggg cttaattttt ctgttcctca aaatcatttt ccagctgatc tccaagaaaa
    37501 agccatctct gtctttcccg acggacaagc tagtgtcaca aggaatcagc taatcagcaa
    37561 aatctggcaa gaattgttca cttatctttc tcacccagaa aaagcgttgg acttctataa
    37621 agaaaaatca ttcgtattgg gaaaaaccgt gtcgttcaat caaaaaggaa cgacttatgt
    37681 cggtcttgca aaagaaatcg gtgatcatgg cgaactgatc gtccaaacaa atgaacagaa
    37741 gatgagtttg tcttctggcg aaatcagtct cacatctatc cgtacgcaat aattatcaga
    37801 tttcacaaaa ggacacctga tctcatacag tgtccttttt tctgaattct cttcaaaaga
    37861 ctctccttat tctatcagct gacagtttct ctatcctcta gaaaaaggta ttctaaaaat
    37921 atctataaag catggtacac tttctttaaa tgaatcaatg caaaaaacaa gagagtcatc
    37981 agtttacacg atcaaaagag atagcaggcc gcttcctttt tcaatcttat agatagacca
    38041 tgggtaacga taaaaacaaa aaagaacttg cgacttattt tgccgtaagt tcttttttag
    38101 ctagtgcctt aatctcttaa tcccaacaaa cgtctcgcat agatcacctg accagagtgc
    38161 atagcagcat catcaataat agaaacgaga cgcattcctc gtgtgactgg tggtgtccag
    38221 ttctcgtcaa ttacttcatc tagctcggaa ggttccagcc ttcttaagta agaaatagca
    38281 aaatcagcag ctcctcgcaa gtatcctagc agatcttcta tttgattagc ttggatctgc
    38341 tttgcttgtt ccagactatg cttccaatct tgttcgttat ctgctatcgt catcggaaac
    38401 cggctttccc agtcttgact atgccaaatt ggagaagttc ctgctaaatc agcaatctgg
    38461 aaatctaatt ctcgagcggt atgccaagcc agccaagtca ttgatttgat ctgcggggct
    38521 ctatcttcca ctggaaaacg attggcctcc tcaatagaga cgccttcaaa caaacgttca
    38581 aaccgatcgt atgcccgatc cacactctcg catagcatat ctaaataatc catttatttt
    38641 cctccttttt atttatccta cttacttttt cctaattcta ggatacctac ttatatgtta
    38701 ctacacaccc ttatttttta cactttaaca gtcaccatca tcaatagttt ggagattgaa
    38761 agaaaaagat agtgtcgaac tatcaattga acaagaagca acaatatgaa cgtttcatta
    38821 atattcttta aataaacaat gatttttcaa acgaacagtt taagactagg agaaaaagag
    38881 tataatagga aaatgtttga aaggaaagga aggggaaaaa tgaaaaaaag ggcaagttta
    38941 ctagtcctag ttgctttgtt gttcaatatc ttttcgtatg gtgtggccgt ttcagcggaa
    39001 acatacattc ctaaagaccc tgggaatatt tataatgatc taactggtaa ctatggcttg
    39061 ttaggaattg ctagtcaatt ccacgtattt gctaaaaata agacaactgt gaatgcacat
    39121 acagacggaa atatagcaac acatgaactt gatgcaaaaa ataattttgg tacagagctt
    39181 catgaaggtt tattgaacca agaaataaat tatatacaaa aaactgattc tttcgctaat
    39241 tcttcaggca tacctacagg tagcacaaga atgaataaat ttgtcgttgg cagtaacgtg
    39301 gatgtagcac ttcaagatgg tcatcctaca gtcaatggat ccaggcttga tcacttaact
    39361 ccagatgatt tttataaaga tcgtgctggg catgaatata ttgatttcga gcaggaattt
    39421 gctaaattga atgtagcagc aaatgatctt gcaacgatca ctccagctaa aacatatact
    39481 gctgcagatt ttccagacat gaacaatcgg acaatcgatt taactgattt atcagatacc
    39541 gggtttttat tggtaaatat cgatgcagaa gtgttaacga tgaatacgcc acttcaaatc
    39601 attaatccaa atgatcaagt agttgtattt aatgtcatca acagttcttc tgcattgaac
    39661 gtacagtcac caatcaaata caatgatcgt tcaaatcatg aaacagaaga tttttcggat
    39721 gcgaatatct cttggaattt tggaaatgag atgactgatt tgacaatcag tgctcctttt
    39781 caaggaacaa tccttgcgcc taatgctact atccgcatta ctcaaaacca agacggaacg
    39841 attataggaa caaatgtgat tttagatgca gctaccaatc gttgggatcc taacgaaata
    39901 tttatcagcg acaatggtac agatacgaca gacacaagcg acagtacaga tacatctacc
    39961 acaagtgata gctcagattc atcaacttca agcgacagta cagatactac ctctaccaca
    40021 agtgatagca cggatacatc agcttcaagc gacagtacag atactacctc taccacaagt
    40081 gatagcacgg acacatcagc ttcaagtgac agtacagata ctacctctac cacaagtgac
    40141 agcacggaca cgtcagcttc aagcgacagt acagatacta cctctaccac aagtgatagc
    40201 acggacacat cagcttcaag tgacagtaca gatactacct ctaccacaag tgatagcacg
    40261 gacacgtcag cttcaagcga cagtacggat acatctacca caacaagtga tagcacggac
    40321 acgtcagctt caagtgacag tacagatact acctctacca caagtgatag ctcagattca
    40381 tctaccacta caagtgatag cacggacacg tcagcttcaa gtgacagtac agatacatcc
    40441 tctaccacaa gtgatagctc agattcatca acttcaagcg atagtacaga cacgtcgtct
    40501 accacaagcg atacacgtca tgcaagtgtc tccttctcaa aaacaagttc ggataacagg
    40561 acgaacttta acttaactaa taaaacaagc aatgacaatg gaaacaaatc aaaaagagca
    40621 cttcctaaaa ctggaagtca atcgaataat tggataacac tcgcaggcgt tatattactt
    40681 gtaatcggtt taagaatcac ttttatgagt tataagaaat cgaaaaggta aaaaaatatt
    40741 caagataaaa aagagcaacg tcgctaacgg acgttgctct ttatttttgc tttttatcat
    40801 aaatacaaga actacaattc aatttgtcaa aaaacacgta gatttccttc tgagaaattt
    40861 atttacgtat cgaacctttc cctattcagt ctttgcgatc caaaatcagt tgggtaaggg
    40921 aaaagagatt ctcttttgtt cgaagagagg tggcaggtaa tttctttatt tccttcaaag
    40981 ccttttctgt gtaagaggcc gctaacttcc tagcttcttc cacgcctcct gtatgttcaa
    41041 cgattttgcg tacggcgtcg acatcttctt ctgtcattgc cgctttcttc tctaaataag
    41101 gtagtagctt tggtttgttt ttttgcaaag agtagatcaa cggtaaagaa tagacccctt
    41161 gacgcatgtc ttctagtaca ggtttgccga tttcctggct ctcttttgta taatctaaaa
    41221 tatcatcgat aatctgaaag gccatcccga tagaaagtcc gatatctcct gctttttttg
    41281 cgaagcgctc gcttgttcca ctttcaaaag cgccaacaga acaacttaat tggaacagtt
    41341 cagctgtctt acctgaaata ttttccaaat attcttttac agaaagttca taattatagc
    41401 gatcatccat ctgccctaat tcgccattca atactttttc catactgcga gaattcaatt
    41461 ggagactttt caaggaagtg gagtaatcag acaatagttt aaaacagcag acaaataaat
    41521 agtctcctgc atagacagaa acgacattac caaactgact acggatatta ggctgaccac
    41581 gtcgcagatc cgcttcatca acgatatcat catggatcag tgtggccgta tggagcattt
    41641 cgatagaagc tgccaaagcg atggctttgt ctcgatcttg ctctggtcca aattgtgaga
    41701 acaatagctg ataggcagga cgcaacagct ttccgccggc atggatcgtt tctttgattg
    41761 cttgttcgac aggtttgttt ttcaggcgga cagtttcttc catccgtttt agtgtttctg
    41821 tcaattcttt acttaaagca ggatagtttt cccacattgg atgtagcttc ataaaaaaac
    41881 tccttgtgtg acgattattt tttggtaaac attgggctcc atttttgttt ggttccctgc
    41941 tcataatctt tttggaatcg ttgaagtgtc tgcacatgtc gtaaaagata attcgctgcg
    42001 atcccgattg caatccctga taaaatccct aaaactgaaa ggactggcaa gtacaacatg
    42061 actgtccatg attgtgcaat gaaagaagcc atcaaaagct gtccgacatt atgcatgaaa
    42121 ccgccggccg cactaattcc gatgatactg acacgttttg gtcctaattg cttgaccaat
    42181 aacattccaa aataactaag caaagcacca ctcatactat aaaggaatgt ggaaatcgtt
    42241 ccgcctagca aagtagtcag gaatagtcgt agccaaagta gtaagaagct gtctcgtttt
    42301 ttcatggtaa aaatggcaac gatcgtgatt agattggcta agcctagttt tgcaccaggc
    42361 gcaaaagaaa aaggataagg gatcatattt tccaataaac caatgatcac tccttgtgca
    42421 acaagtagcg aaatataaat cattttttgt aatttactca tggtgtgtga aggtctaata
    42481 aatcagactg tcttcgtcac ctccatctgt tgaacggact tcgatcacta atttatgtgg
    42541 caaacagacg atggtttcgc catttttcgt tgcccagcct cgacgtacgc agatctggtc
    42601 atcgcaatct gcttctttta tccgtactcg atcgccatct atctcgatca agttataatc
    42661 tccgtgttca tctttgtaag tatatgtgtt gctctcttct ccagccatca aagggaatgt
    42721 tttgatttct gtgccatcca cacgtagtac cgcttctttt tctgctgttg cggtgttttg
    42781 ctgaagacca aaaatcatga ctggtaaaaa agaaagaaca gtcaaaagca aaataataaa
    42841 aacatcccaa ggtttgagca gacttttttc agcaaattct ttaaggctca tttttgttct
    42901 cctttttcca gattaactca cccaatttta gcataaaaac aagaggttgt gacacctgtg
    42961 tcttgctttg agtaataaga acgaagaata gaaaacagct ttccatgttt tctaattctt
    43021 tgggcttatt accgagaagc agcaggtgga acaccgttta taacaagagg ttgtgacaga
    43081 agtgggcaac ttcaagaaat aagaaggaat ttacgaaaat tacttttcaa gtttttgtga
    43141 aatttcggct tatttttcga agaagctact tctggaacac cgtttataac aagaggttgt
    43201 aacagaggtt gtgacacctg tgtcttgctc atggaggctt atctcgggca tcttattcct
    43261 ttaattttac ataaaaagga ggctgtgacg gtttgtctca gcccctttct attgaaatct
    43321 tgcattcaaa taacgttctt tatctattta tttcttgccg tactgggaac ttggtctacc
    43381 gtaccaccaa ttacctagtg tacgttgtag ccatggaatt acccagcgat ccaacccaat
    43441 cgcacgtccg gaaccgttca tcaatgcgaa agcaacaaaa atgaaccaaa tgtttaccca
    43501 gtaaaacatg cctgataagc agaacgtgat caccaataca atcgttgtcg cactgcatag
    43561 ccatgtgaat aatccagcaa tcaatgctaa tgccaaggca atttcaaaga ataccatgaa
    43621 tttttggaag aacattgcta catcattgtt tggcatgatc acttgcatga tctttgtgaa
    43681 ccagtctggt gacttctcaa tcacagccat tggttcttca ccgtatgcat aactcaaacc
    43741 aaaatgtgca gcttgagtcg ctgcttctcc ggcacttgcc cctgctccgc tggcagctgt
    43801 ggttgcatca ccagcagcag aagcaccact ggcaacatct gttacattgt attcccatgt
    43861 ccaagggaac acactgtttc cagtgaacca tgatccttca ccaaaccaag tacttggttt
    43921 gaacacttca ccattcccaa tgattttttt ggaagcttca acgaaccaaa ctaaaccata
    43981 gaaaatacga agtggcacac tccataagac attgccgtaa cgagaagaat gtcctcgagt
    44041 cacgttgcga tcatctttga tatggaaaaa ctcatgcatt aaatattgga acatataata
    44101 accagaacga atatcaaaga agtatttcaa attcacgata tgtttcatta cgatagctaa
    44161 aaatccgctt aaatggatct tatcaaatag gttagctacc ccccatttgg caccaataga
    44221 aaccataaat ccttgatagt ttcctttaaa tttatgcttt tctccgcctt tgatcgaagc
    44281 cacgatattc gctgcggctg tgtgtcctgt ttgttcagca gcttgaacga tctgcggtgt
    44341 cggtgttcct gggaattctt cataaaagac taaatcacca atgatataga tgtttttatc
    44401 ttcgtagcct tttgcctgca tatattcatt ggcgatcaac cgctgtccgc gtgctgattc
    44461 taatccaaag tcagcagcgt cagaagttcc tttgacacca gctgtccaaa tcagtgtgtg
    44521 agtcggaatg ttgcgtccgt ctttcaattt gatatgatca gcagccactt ctacgattgg
    44581 tgcattcaat aataattcca cgttgtgctt acgcaaatag cgttcagctt ttgcagcatc
    44641 atttcgatcc aacatattca agatcgtcgg cattgcctct acgaccatca gtgtgatttc
    44701 gtttggatct aatttataat ctttggctag gcgatttttc cagtcgatca gttccccaat
    44761 catttcaata ccggtaaatc cagaaccaca gacaacgaaa gtcagcatgg ctttacgcag
    44821 ttcatcatct ggttccaatg cagcttttgc tactgtcttc tcaatatgtt cccgaatcct
    44881 tacagaatct tcaaatgacc aaagggtgaa tccgtgtgct ttgacaccag gtgtaccaaa
    44941 gtcattcggc tctccgccca ttccaaggat cagctgatca aaaggatagg aacctaattt
    45001 ggtcttgacg atttttcgtt ctttatcgat accgattaca gtgtctgtga caagttgtac
    45061 attcttttga cgagcaaaca aatgctgcag atcgtattgg attgcttctg gttctacacg
    45121 tccgccagct acttcatgca actcggtcat catagtatgg tacgaatgac gatcgatcag
    45181 agtaattgct acatcttctt ttttcagttt ctttgccaag tattttgtag ctgaaacacc
    45241 ggcatatcct gctcctacaa cgacaatatt ttgctttgcc attgatcatc cgctccttat
    45301 agactatcta tataatgaat atatgataat tcttttagtt tgatacttat tacacaatct
    45361 ccatatatta tatagatgtt ctgttctttt gtctaactcc ttttggattt ttttcaaatt
    45421 ttaaaataaa gcgttttttc acgaaatttg ctgaaagaaa acgtttgaaa tattacatgg
    45481 gttatttatc aaaaatagtt gacttatagg ctaaaaagat tagaatgtat aatgaatcac
    45541 aaagaaaaat tgtggactag aaatggaatg gtggggtatt aaaatgaaga aaaaacgttt
    45601 tgtaactgga tttgccgtat tagcattttc agctctagtg ttaggcgctt gcggcgcaga
    45661 tgacaacgga agctcaaact cttcttctga atcatctaca gcacaatctt cgactgcaaa
    45721 aagcacaaca gaatcatctg caaaagttgt agctggcgga gatttgcaag acggcacata
    45781 taaattagaa gaaaaaaatt attcaaatgg ttaccgtgca gtctttgaaa tggttgtaaa
    45841 agacggcaaa atcactgaat caaaatatga taacgtcaat gaaaacggcg aatcaaaaac
    45901 aaaagatgca gaatacaaca aaaacatgga agcaaaatct ggcacaaacc cagaaaaata
    45961 cattcctgag ttgaatgacc aattcttaaa agcacaaagc gcaagcggtg tggaagtcgt
    46021 aactggagct actcactcat ctgaaagctt ccaaaactac gcacaacaat tgatccaagc
    46081 tgctcaagct ggtaacacag atacaatcga aatcgacaat ggtgctgatt tgaaagacgg
    46141 cacttacaag cttgaagaaa agaactactc taacggctac cgtgtgcaat tcgaaatgac
    46201 agttgctggc ggcaaagtaa ctgaatcaaa ctttgattat atcgacaaag acggtaaatc
    46261 aaaacaagat gatacagaat ataatgaaaa tatgaaagca aaaagcggta cagaaccaaa
    46321 aacttacatc cctactctga acgacgaatt cgtcaaagca atgggcgaag aagatggctc
    46381 acctgctaat gtagaagttg ttacaggtgc tacacacagc tcacattcat tcatcatgta
    46441 cgcacaacaa ttagtgaatg cagctgaaaa aggcgacact caaacaatcg aagtagataa
    46501 tatcgtaaca gaaaaataat cacataatca tactaataaa agttggaggg tgggacgata
    46561 gccagattag gcagtcgtct cacctttcaa aatgaagaga ggaaaaagat gcggaaaaaa
    46621 ctactatttt ccttaatcac actgggcatc tcttttatgg tgctaactgg ctgcagcaac
    46681 tcagcaaata aaacaaccac tgaaagttca gcagctacca agatattgaa agatccatat
    46741 tctgatgaac agttcttgtt agggacttac gttcgtatcc gtgtgtatga tgaaggcaaa
    46801 gaatcagcat tgaaacctgc cttcgatcga gtaaaagaac ttggtgataa aatcacgatc
    46861 aatcaaaaag gttctgagat cgatgaagtg aatgagcaag ctgggatcaa accagtaaaa
    46921 gtttctgatg acgtctacac gttagtcaag cgggcctacg aatatagcca agattctcaa
    46981 ggcggattcg atatggcgat tggtgcaatc acacaattat ggcgaatcgg ttttgatgac
    47041 gccagaaaac cttcccaaga agaaatcgat caggcattga aattagtgga ttatcataag
    47101 atcgaactaa atgacaaaga aaaaactgtt tatctaaaag aaaaaggaat gatcatcgat
    47161 ttaggtgcaa tcgccaaagg ttacattacg gacgaagtag tgaaagtctt gaaaaaacaa
    47221 ggagtgacca ctgccatcgt tgacttgggc ggtaatgtct atgtcttagg ccacagccca
    47281 agaggcgaaa accaagactg gacagtcggc atccaagatc cgaacatggc tcgcggatct
    47341 gttttaggtt ctattaaaga acggaacaaa acattagtta cctctggaat ttacgagcgt
    47401 tatttagaag tagatggcaa aaaataccat catttgtttg atccaaaaac gggttatccg
    47461 ttcgacaatg atatcgcaag tgtcacgatc ataacagata aatcaattga tggtgacggg
    47521 ttgtctacag cagtcttttc aatgggtgtg aaaaaaggac tggaatacgt cgaaagcgaa
    47581 ttgaataacg ggacggaagc gatcttcgtg acaaaagacg ataaagtata tgtgaccgat
    47641 ccaatcaaag acaccttcaa attatcggag gactcccatt acacgatggg tgaccgttct
    47701 gaactaaaat aaggagtacg aaccatgaca ctaaaaatct ttttagaagt agttgaaata
    47761 cgaacaaagg tggctagtgt atttcctttt gcggtagggg tattattctc tatcgctttt
    47821 tttcatgaga tacattggct aaacactttt ttatttttta ttggaatgct agtttttgat
    47881 ttagcgacta ccgctatcaa taattacatg gattatgaaa aggctcattc tgaagtatat
    47941 aagtatgaag aaaatgtcat tggccgcaga aatctatctc ctgtattgat tcgaaacatg
    48001 attttagcta tgattgcatt tgtttttgtt atcggcgtta ttctaacgat caatacgggt
    48061 tggcttttac ttttgatggg atttatctgt tgttttattg gagtattcta tacattcgga
    48121 ccgattcctt tatctcgaat gcctttaggg gaaattttca gtggggtgac tatgggcctt
    48181 ggaatttttg ccatggtcgt ttatgtcaat acattcggtt cagatgtcta tgatctgaca
    48241 gtcaactttt catctggaca atttgctttg gtaggaaatc tttgggctat agcagcaatc
    48301 gtattagctt ccttaccctt ggtgtttacg attgccaata tcatgttggc taataatttg
    48361 cgggatcttg accgtgatat tgaaaatcat cgctatacac tagtttttta tatcggacgt
    48421 cctgcgggaa cagtcttatt ccagctattg atgtatgctt gctatttcgt gattttaatg
    48481 gggttgttga gcggtatcta tgaatggccg atcttggtca ccttcttgac cttgccaatt
    48541 gtgaagaagc atttggatca attcaagcaa acgttacccc agcctatcag tttcagctat
    48601 tccatcaaaa atatggtctt attcaatgcc agttatgtat tggggctatt actaacaatc
    48661 attatgcaag ccatttaaca gcatgaagag gttgtgaaaa aactgccctg catcaagtaa
    48721 taagaacagc caaataaaaa tagctcctta tatttttcgt ttggttgggc ttattaccgc
    48781 agatgcaagc ttttgaacac cgtttatca
//
LOCUS       DAPBBV010000022        47710 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.022, whole genome shotgun sequence.
ACCESSION   DAPBBV010000022 DAPBBV010000000
VERSION     DAPBBV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.022"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(448..978)
                     /locus_tag="RD486_001486"
     CDS             complement(448..978)
                     /locus_tag="RD486_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HDT7663221.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            1083..1634
                     /locus_tag="RD486_001487"
     CDS             1083..1634
                     /locus_tag="RD486_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7663222.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(1787..2260)
                     /locus_tag="RD486_001488"
     CDS             complement(1787..2260)
                     /locus_tag="RD486_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7663223.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            2398..3870
                     /locus_tag="RD486_001489"
     CDS             2398..3870
                     /locus_tag="RD486_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7663224.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            3867..4577
                     /locus_tag="RD486_001490"
     CDS             3867..4577
                     /locus_tag="RD486_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HDT7663225.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            4929..5213
                     /locus_tag="RD486_001491"
     CDS             4929..5213
                     /locus_tag="RD486_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HDT7663226.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(5494..5913)
                     /locus_tag="RD486_001492"
     CDS             complement(5494..5913)
                     /locus_tag="RD486_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HDT7663227.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(5915..6499)
                     /locus_tag="RD486_001493"
     CDS             complement(5915..6499)
                     /locus_tag="RD486_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HDT7663228.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(6546..8021)
                     /locus_tag="RD486_001494"
     CDS             complement(6546..8021)
                     /locus_tag="RD486_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDT7663229.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            8202..8513
                     /locus_tag="RD486_001495"
     CDS             8202..8513
                     /locus_tag="RD486_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663230.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(8628..10964)
                     /locus_tag="RD486_001496"
     CDS             complement(8628..10964)
                     /locus_tag="RD486_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7663231.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            11106..11774
                     /locus_tag="RD486_001497"
     CDS             11106..11774
                     /locus_tag="RD486_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7663232.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            11777..12820
                     /locus_tag="RD486_001498"
     CDS             11777..12820
                     /locus_tag="RD486_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7663233.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(13057..13938)
                     /locus_tag="RD486_001499"
     CDS             complement(13057..13938)
                     /locus_tag="RD486_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7663234.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            14097..14825
                     /locus_tag="RD486_001500"
     CDS             14097..14825
                     /locus_tag="RD486_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDT7663235.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            14981..15298
                     /locus_tag="RD486_001501"
     CDS             14981..15298
                     /locus_tag="RD486_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7663236.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            15291..15899
                     /locus_tag="RD486_001502"
     CDS             15291..15899
                     /locus_tag="RD486_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDT7663237.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            15954..16745
                     /locus_tag="RD486_001503"
     CDS             15954..16745
                     /locus_tag="RD486_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDT7663238.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            16883..17371
                     /locus_tag="RD486_001504"
     CDS             16883..17371
                     /locus_tag="RD486_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDT7663239.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            17422..18294
                     /locus_tag="RD486_001505"
     CDS             17422..18294
                     /locus_tag="RD486_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDT7663240.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            18470..18832
                     /locus_tag="RD486_001506"
     CDS             18470..18832
                     /locus_tag="RD486_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7663241.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            18841..19593
                     /locus_tag="RD486_001507"
     CDS             18841..19593
                     /locus_tag="RD486_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663242.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            19607..21409
                     /locus_tag="RD486_001508"
     CDS             19607..21409
                     /locus_tag="RD486_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663243.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            21686..22726
                     /locus_tag="RD486_001509"
     CDS             21686..22726
                     /locus_tag="RD486_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7663244.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(22778..24922)
                     /locus_tag="RD486_001510"
     CDS             complement(22778..24922)
                     /locus_tag="RD486_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7663245.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(25279..26652)
                     /locus_tag="RD486_001511"
     CDS             complement(25279..26652)
                     /locus_tag="RD486_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7663246.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(26652..27047)
                     /gene="rbsD"
                     /locus_tag="RD486_001512"
     CDS             complement(26652..27047)
                     /gene="rbsD"
                     /locus_tag="RD486_001512"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDT7663247.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(27075..27992)
                     /gene="rbsK"
                     /locus_tag="RD486_001513"
     CDS             complement(27075..27992)
                     /gene="rbsK"
                     /locus_tag="RD486_001513"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDT7663248.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(28100..29113)
                     /locus_tag="RD486_001514"
     CDS             complement(28100..29113)
                     /locus_tag="RD486_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7663249.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(29194..29793)
                     /locus_tag="RD486_001515"
     CDS             complement(29194..29793)
                     /locus_tag="RD486_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7663250.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            29979..30680
                     /locus_tag="RD486_001516"
     CDS             29979..30680
                     /locus_tag="RD486_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663251.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            30690..33401
                     /locus_tag="RD486_001517"
     CDS             30690..33401
                     /locus_tag="RD486_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663252.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            33852..35480
                     /gene="treC"
                     /locus_tag="RD486_001518"
     CDS             33852..35480
                     /gene="treC"
                     /locus_tag="RD486_001518"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDT7663253.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(35540..36721)
                     /locus_tag="RD486_001519"
     CDS             complement(35540..36721)
                     /locus_tag="RD486_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7663254.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            36973..38496
                     /locus_tag="RD486_001520"
     CDS             36973..38496
                     /locus_tag="RD486_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDT7663255.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(38565..39293)
                     /locus_tag="RD486_001521"
     CDS             complement(38565..39293)
                     /locus_tag="RD486_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7663256.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(39306..40586)
                     /locus_tag="RD486_001522"
     CDS             complement(39306..40586)
                     /locus_tag="RD486_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7663257.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(40727..41329)
                     /locus_tag="RD486_001523"
     CDS             complement(40727..41329)
                     /locus_tag="RD486_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDT7663258.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            41574..41780
                     /locus_tag="RD486_001524"
     CDS             41574..41780
                     /locus_tag="RD486_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663259.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            42092..42811
                     /locus_tag="RD486_001525"
     CDS             42092..42811
                     /locus_tag="RD486_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7663260.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(42892..43575)
                     /locus_tag="RD486_001526"
     CDS             complement(42892..43575)
                     /locus_tag="RD486_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDT7663261.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            43793..45979
                     /locus_tag="RD486_001527"
     CDS             43793..45979
                     /locus_tag="RD486_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDT7663262.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNISVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            46325..46735
                     /gene="spx"
                     /locus_tag="RD486_001528"
     CDS             46325..46735
                     /gene="spx"
                     /locus_tag="RD486_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDT7663263.1"
                     /translation="MIKVYTSPSCTSCRKAKAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            46749..47105
                     /locus_tag="RD486_001529"
     CDS             46749..47105
                     /locus_tag="RD486_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HDT7663264.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        15500 a         8421 c         9499 g        14290 t
ORIGIN      
        1 tttttgctgg gagcattatt tcattttgaa gtcactaatt taactgtgtg aatatgcagt
       61 tgttacaatc tttgataaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac
      121 ggcaaaatat gaggaactat ttttccattt gtttctctaa tactcaggtc aaaacgctga
      181 tttcacaacc tcttgataaa cggtgttcaa acggctgctt ctcggtaata agcccactag
      241 cctagaaaat atgaaaagct attttctaac tagcgttctt attactcaaa gcataacgct
      301 gatttcacaa cctcttgata aacggtgttc aatcagctga ccctcggtat tagctcaaaa
      361 aacggcaaaa catgaggaac tatttttccg tttctttctc taatactcag gtcagaacgc
      421 tgatttcaca acctctcttt cacaacctta ttttactcgt ttataatttt catcgaagta
      481 ttttccgcta cggatatcat ctggcattcc atcgtatggt tcttcgctaa taacatcttc
      541 attgtctata cctgcatcac ccatataagt gatcgtagca aattcaggaa caagtaattt
      601 tggataagtt tcatattttt cacgagctgc ttccatttct gcgatatgtt cgttttggaa
      661 agtaacagtg atttctggat gttcttcaac ccatttaggg aaaaagatca ttccgtgaag
      721 tttcttttca tttggcataa agtccaatgc cacgtctgtc cctgttggct ctgtccaagt
      781 gattttgaat acgccgtccg tcaatttaac gatatcagct tcttggtctt ttacccaacg
      841 gcctttgacc attccgccat ggatacggta atcaacagta tggtcatttt tggcatacca
      901 ttcatattcc caaccattgt catacgtata gataaagtga gttccaataa aatcttccaa
      961 ttctttaaat tctttcatgt ttaagcatct ccttataaat taaaacatgt aataaactac
     1021 atgttttcga ttactcattt atgatagaat ggatttaaag atttgtcaag gagggaaaac
     1081 tgatggcaag aaaaaataca cttcgatata ttttgttagg gttattaagt aagaagaaga
     1141 tgacaggata tgaattgaat caatcgttca aaaatgaaat aggagaattt tggcaagcaa
     1201 aacatagtca gatttatcct gaacttgcaa aaatggaaga gcaaggaatc attcagcatc
     1261 aagtagagat cacaggtgaa aaattggaaa agaaagttta tgaattaaca gaagaaggga
     1321 aggaacaatt ggcagagtgg attcatacac ccaccaatga actaccggtt aatcgagacg
     1381 aatttgttct gaaattgtat ttcgtcaaag acgtgaatga tccggcatta gtagaaatta
     1441 ttcagcagca gcgtgacctt catgaagaaa aacgacttca tctattagag cgaaaaaaaa
     1501 cgatctttcc tactgaaaaa gaaaaacatg aaaattacgg acactacctg attttagcgc
     1561 atgcgatcaa tcgggaaaca gaatatgcaa attggctaac agatgtatta gaagaaagta
     1621 accgaaaaaa ataaaaaaat atccgaacag tgatggagaa ttcctttcta tatgaaagaa
     1681 acgcagatca ccgttcggat attcttatgt tcaaacaggc cttttttcaa gtatttatgt
     1741 agcatctact tattaaaaag cttggtactt aggagattag tggcgtttag agttctttta
     1801 acaactgttc gtagtcagct ttttcatcga caggaaggag cttgtaagtt aattcgtctg
     1861 tctcgttgtc atgaatgatg tacatcttag cattctcttc tttgaagtta ccgatttgta
     1921 aaatcgtata gcgttcgtcg atcaattcga tatctttgat tgcttttgaa aaaactttac
     1981 ggacatggtg cattttcttt tggcggattt ctgccttttc tgcagctttt gacaaagtaa
     2041 atccgtcatc taaatatttt ttgatcagtt ctacttttat gactgtaggt aaacgatatt
     2101 ttctaggaca attcgcatca gcttcgatcg aacgaatgaa tcccttttgt tcccaatacc
     2161 ttaattgacg tggagacaca cctacgatat cacttaattc actgatgcca acaaccaatt
     2221 gatcattttc caacaaacgt ttaagggaag ccccaaccat ttttgtcact ccttttgtcc
     2281 tcttgcttcc cttaattata tccgtattaa cttatgtgtc aagtaggttg acaaatagcg
     2341 aatttaggac taaagtattc tagtagtttc agaaaaaatt cagaaagaag gagaaatatg
     2401 agtaacaacc aacccgtaga tatttacgga aaaccatata atcggacact tttagttgtt
     2461 gtcttattaa ttggtacatt ttgtaccgtt ttgaatcaga ccttattgac gacagctttt
     2521 cctacattga tgaaagcttt cgatatttca gcgtctgatg tgcaatggtt aacgactggt
     2581 ttcttgctag tcaacgggat catgatccca ataacagcat ggctgatcaa taaattcagt
     2641 tcaagaaatt tatatctttc tgccatgacg atctttttga tcggaacgat tacttgcttt
     2701 acagcaccta attttagtac attactaatc ggtcgtttga tccaagcttg cggtgtggga
     2761 gtatcgatgc cattattgca aaatatcatg ctatctattt tcccgccaga aaaaagagga
     2821 tcagcaatgg ggatgtcagg gatcgttatt ggacttgctc ctgctttagg ccctacatta
     2881 tctggttata tcattgataa ctaccattgg cgtgacttgt ttggtatggt actgccaatc
     2941 gttgttcttg tcttggtttt agcattcttc ctaatgaaaa gtgttattcc attgtcaaat
     3001 cctagcattg atattttatc cgctatttta tcaacgattg gattcggtag tttactttac
     3061 ggattttcta gtgtaggaga tgacggctgg ggaagcttga aagtaattgg tttcttagtt
     3121 gttggtgtga ttttcatcgc cttgttctca tggcgtcaat tacatttgga acatccattc
     3181 ttggaacttc gtgtattcaa atcatctaca ttcacgattg cagctgtttt agctggtgta
     3241 acaaatatgg cgatggtagg ggcagaaatg gtcgtaccat tgtatattca aaatattcgt
     3301 ggagaatcag cattccattc tggcttgatg ttgttgccgg gtgcattgat catgggggct
     3361 atgatgcctg tgacgggtgc gattttcgat aaatacggcg cgaaacgttt agccatcaca
     3421 gggatgttca ttttgacagc ggcaactgca ccatttgctt tcttgacaaa aacgactcca
     3481 gttttatata tcgtgatcct ttatgcgatc cgtatgtttg ggatctccat ggtcatgatg
     3541 ccggtaacga cttctggtat gaatgcattg ccaaataact tgatcagtca tgggacagcg
     3601 gtaaataata cattccgtca aatcgcaagc tcgattggta cagctatttt gatcagtgtg
     3661 ttgacgaatg tgacaaaagc aaatatccca agcaaatctg tattggataa tacgccatta
     3721 gcttataaag atcaggcaat caatgccaca ctgtcaggtt accatgccgc gtttatcgta
     3781 gcgatcatct ttgggattct tggctttatt attgcctttt tattgaagaa aaaagaacct
     3841 gttctaatga aagcggggga taatgcatga ttattggagt tttgattgtc agcttgcttg
     3901 cttttgcttt aacgaacgtg ttcgctaaaa aaacatggca aaccttttta tctttgattt
     3961 tcggactaat cttcgtcgct tcactaagtt tgatcgtcgc taatttgtcc aatcactttg
     4021 gaatggaaaa agtaacggaa acaaaaacag aaaaaattgt ttccagtgct gattcccaag
     4081 gagcagatat gcttttgtat aaagctttag ggaatggaaa agaaaaagtg tatctttacc
     4141 gaacaaatga aaaacaagaa aaaccaaaag caactggtac ggataacgaa acaaataaag
     4201 tagaaaagac agacggcgat gctgaaaaag tgacgaaaac tacttattgg gaatacaaaa
     4261 acgacatgta taaattctgg ttcaatattg ctgataacaa tcacgaatat gacagccgag
     4321 tgaatacatt caaaatccca gagacatggg tagaattaag tacggaccaa gcagccaagt
     4381 tagctgaatt agtgaagaaa cagcaaagta cgatggaaag tgaagcaaaa gcttatgttc
     4441 aagacggtat ggtaaaagca atgactgaaa atccaaaaat gagcaaagca gagcaagaac
     4501 aacgtacgaa agccttagct gctgaattcc aacaacaagc attcgcaaaa ttagtgaaag
     4561 aagcaaaagg cgaataatat tttgaacacc atgtaggagg ttgtgaaaaa gctgctctgc
     4621 atcaagcagt aagaacaatc agataaaaat agcactccat atttttcatc tgattgggct
     4681 tagtgccgta gatgcaagct tttgaacacc gtttaaggaa gaggttgtga gcctgccgtt
     4741 taactctgag tcacaaggag caatttcaaa aaacagcttc tcatgtttgt tgactattgt
     4801 gacttgtgac cgaggagttg gcaggagaac accgtttatt cgaaaaaagg aactgcgaca
     4861 agacttttgt cacagttcct tctttttttt gctatgctat actagatgta aaaaatagga
     4921 gaaataaaat gagggaaatt tattcttttg aatcaaaaat ctatgcttcc gaagtcggca
     4981 agggcggggc atatattatt tttccgtatg atataagaaa agaattcggt gctggaagag
     5041 ttaaagtcca agcaactttt gacaatgtgc cgtatgaagg cagtatcgtg aatatgggcg
     5101 tgaaaaatcc agatggttca gtctgctaca tccttggact acgaaaagat attcgtaaaa
     5161 acatcggaaa agaaatcggt gatattgtag cagttacagt gaagcaaaaa taaaagaggt
     5221 tgtgacaaaa gacgtgtcac aacctcttga taaacggtgt tcaaaagcca gtttctcggt
     5281 agtaagtcaa atttatgcaa aaatgtggaa acccatgttt acaaaatttt tcttactact
     5341 cgaaacgaag cggctttatc acaacctctt gataaacggc gttcaatcag ctgtccctcg
     5401 gtattagctc aaaaacggca aaatatgaga agctattttt ccattttttt ctctcatact
     5461 caggtcataa cgctgatttc acaacctctt ctttcataat ggtttttcac catctttata
     5521 ataaactggt tctttgatat ggaaatctat tttttccaac caatctaaaa tcttgtaacc
     5581 taactcttct gacatcggaa aagaggcgtt gatttgtgca ttggagatat ggtcaacatg
     5641 gataccggaa gtgatcgtac aacttcccgg aacggcagtt ttgatgatca cagctatttt
     5701 ttcggctaag acatcgtctt tatggaaccg accatcgtgg ctagggaaac gtacagtttg
     5761 catctctgta tcacgagaaa atgtagtgac tgttccgata tgtggtgtat ctccgcctgt
     5821 taaagtgatc aataagtctt taccgattac tttaacagca gcttggatcg tgaaacctag
     5881 tttggttact tcaactatcg tttctttttc catattaatc accctgccaa cgttttgaat
     5941 gctcatttac aatttcaaat tgatccaaaa gtttcattgt atggtgatta acaagatctt
     6001 ggatcgtttg aggctgatta taaaaagcag gaattggtgg tatgatttgc acacctagtc
     6061 gtgctaattt agtcaagttt tccaagtgaa tggcatttaa tggcgtttca cgaggaacaa
     6121 tgactaactt tcgttgctcc ttcattgtta catcagcagc acgtgcaatc aggttgtcgc
     6181 ctaaaccaac agagatacct gcgactgttt tcatacttgc cggtacgatg atcattccat
     6241 cggtcaaaaa tgatccgctg gcgacagcag cacctaaatc tttgtttgaa taatggtaat
     6301 caaacaggct ttcgaattca gttagtgata agtcggattc cagctttaag ttctgttttg
     6361 cccatggact gatgattccg tgtgtttcta tcatcggata ttcttttagt ttcttcacta
     6421 ggttgatggc ataaatggtg cctgaagcgc cacttacacc aatcacgatt tttttcttcc
     6481 gttgtgccaa ttgttccatt ttccgcactc ctttttatga tgtcaaaaca gttgcagatc
     6541 attcattatt tcaaatattt ttcccaatct tctacttctt ggaattttgc acgtacaaaa
     6601 tgttctttca tatcgaaagg aactgtaccg tcaaagatag tttttgcact tatcccacgg
     6661 aaacgaatag agccaggatt atattctggt aattctgatg ggtccaatgg atggttcctc
     6721 attcctggga tcacgatgat atctttatct ccttggaaac gagtgttgaa agtccaaact
     6781 acatcgttca tgtcgaaaat atcaacatct tcatcgacta aaatgactgt cttcaattct
     6841 ttgaaggctg ataaagcaag aatagctgct tgacgctgaa taccttcatc cgcttcgttt
     6901 tctttacgga tttgcatgat ggtcatcaat ttaccaccac ctgcaggagg attgtagaca
     6961 tttactactt ttcctggaat agctttatcg accaaggcaa gaatacttgc ttctgtagga
     7021 ataccggcca tagatacgtg ttcttcactg ggaccaatcg ttgtttgcat gattggattg
     7081 tcttttcggt gagtaactgc tttgactttc actacttgta cagctggatt agcatcccca
     7141 gtatagccag gaaattctgg cattgctttt cctgagttcg tgttgatatc ttcttgcatt
     7201 gtttcatttg gcatgatttc tgcttcaatg atgaattcag cacgagcaat acccacttca
     7261 tcgactgcta taccatcaac gatttgaata ggttcgttac gcaaagctcc tgcacaccat
     7321 agttcattgt agccaagtgg agtggtaggt ggttcgaaag tcgtgccaat ggcaattgct
     7381 ggatctaaac caatattgat agtgataggc attggtttat tcaaggcttc gaattgtttt
     7441 tggaagtgac caatgtggcg tccgccaggc atgatgtaca taccgatcgt atctttatct
     7501 tctagaacca tacgatggat cgttacatcg ctcattgttt tttctggatc tgatcctaag
     7561 actacaccca ttgtgatgta tggaccagca tcttcaggag tatttgtagg tgcaggcaaa
     7621 atgttgcgaa tatcgaagtc tgcatcggta gctagatgaa cgacttcttg tgctggagcg
     7681 tctgctttgt ctactttcac aggtttgatt ggattttcta cagcgtcttt caagaaacga
     7741 ccaagtgttc gataatcatg gtgcaaaatt tcacctacac gtttacgact agccattgtt
     7801 ccgatgttca cacgtgtgcc ggggaaacct ttgatattgt tgaaagtcat agctggtcct
     7861 tcttgagtcg gacgttttac tgtaccgcca gcaccgatat aacggtaaac accagataat
     7921 tctgcttcag gatcgatttc aatatctgtt tcgtgatatt gacctggaag tgtttttagt
     7981 tcttcgatga cttttcttaa atcatacggt tgatctgtca tgagagattc ctccttagtt
     8041 gtctttacct atctatagta aaaggtgaaa aagaggaaaa caattcaact tgttcggtaa
     8101 agtattctac aatggaatgg atgcgttttt ttgataatag aataaactat gatatactta
     8161 tcactaaaag aaagcgcata cttagtgttg gaggaaggaa agtgaaaaaa atggaggagt
     8221 catttcctaa agcagtaaaa gtggaaaata tagcgaatat tttgaaagtt acatttgaaa
     8281 acggagaagt aaaatacgtg aaatctcatt ggacagaaga gataaccgat gccttgcaat
     8341 ttggaaaaaa aggaagagga aaaagaaaaa atcttctcgc actttctcgt aatatgtgga
     8401 ttgggactga agtaacgatt gaagcagatg gaacagtatt cataaatgga aaagacaggt
     8461 atacgccaga agagttgtgg tacaaaggaa agaaaagtat accagaatta taaaaaataa
     8521 ttaaaaaaaa cagcgcgaaa caaggaacat attacttcct cgtttcttgc tgttttctac
     8581 tatttcagcg ctcttatgac tcaaatctaa atgtggttgt cacaacctta ttctgcacgc
     8641 aaagcgatag cggcgtcttt tttcgctgcc attcgtgcag gaagatgacc gccaagcatc
     8701 gtcaatatag tagagacgat cactagaata atcgcatgga caggatttag ttgagcaaca
     8761 ttttttagat ccgtcatgtt gtataagatg ctattgatag ggaacgtagc tagccatgca
     8821 ataaacacac ctaatatccc agaagaaata cctaaaatac acgtttctgc gtcaaatacg
     8881 cgagtgatgt cttttttacg tgcacctaaa gcttttagta caccgatttc ttttgtccgt
     8941 tcaatcacag atgtataagt aatgatactg atcatgatca tacttgttac taaagagatc
     9001 cctgcaaaag caataaggac ataagtgata gcatccatca atccgccagt cagttcagtc
     9061 atcgttccag ctaaatcagt ataaatgatt ttatcttcat ctgatttgcc tttattgtaa
     9121 tcatctagat aatccaagat cttttctttg tcttcaaaat tgttcggata aatcatgata
     9181 cttgaaggca agctgtctcc acctaaataa ctaagcaatg tttgtttggc attttcgtca
     9241 actttttcag tagttaagac atttacacca ctgtctcttt gagctttgac gatttctgat
     9301 tctttgtttt cgttgacgat ttgagtcgtt aattgatcgc tataagcgat tcctggagat
     9361 aagagattca ttgtagaaga agatttcacg cgtaggatcc ccgagatctt caattcatca
     9421 gaagcattct gatacatcgc atcataatct gtattaggga taaaattccc agttggaagt
     9481 tttgtatagt aagtattgtt gtttactaat ttgaatgttg taccaacgat atcatcaaaa
     9541 tcaagttttt cgtcttcttt cacatcaaat ccaagattct tcaatgcgtt gatattagta
     9601 ttattattgc cgtctacgat cagcacgaca tctgttgctg aggctggata acttccggca
     9661 agtaaagaat aattgtcttt taaaaagttt tctttgctag tgtcaagctg tgtagggaaa
     9721 cttgacactc ccacacctgt cattgctgac atcgtactag ataaagaaag agattccgta
     9781 tcaggatttt gattcgagaa gctgacaggc tgtactttgc catttacatc acgtaaaaga
     9841 ttgattcctg tagtacgggt aaatccgata ttattactta agttaggatc gatgtctgtt
     9901 acgtaatcga cgtatgtttg atcaatctta ttcgtgtgct gtgctttatc ttcttcgctg
     9961 acttttgcag taatcgtttt gctgtctgga taatccgctt tgcttgcacc caatccggca
    10021 tcgtcacgag tctggttagt cgttacctta gaaatagtaa tcggaaattt cgccatcgtt
    10081 tcagcttgcg tgttatcgat ttgtttttgg aatccagaag aaagggacag aacgatcgcg
    10141 attccgatga tcccaatact ggaagcaaag gaggtcaaga aagtacgtcc tttttttgtt
    10201 cggatattgt tgaaggaaag ctttaacgct gtccaaaaac tcatctttgt tctgcgtaag
    10261 ttaaattgat catcttttgg tcgttcgatg tgaggatggg aatctgttaa gatcttacca
    10321 tcagaaaatt caatgattcg atctgcgtat tgatgggcca gttcaggatt atgtgtgacc
    10381 atgatcacta atttttcttt cgataactct tggatcaatt ccatgatctg gatacttgtt
    10441 tctgtatcta acgctccggt tggttcatcg cacaaaagga tatctgggtc attggctagt
    10501 gctcgagcga tggccactcg ctgcatttgt ccaccagata actgatttgg ctttttatgc
    10561 atatgatttg tcaagccgac tcggtgcaat gcatcttctg cccgttttcg tttttcgtct
    10621 ttagaaacac cacttaatgt catcccaagt tcaacgtttt caataatgcc tagatgacca
    10681 atcaagttgt aactttgaaa aatgaaaccg atagagttgt ttcggtaggc atcccagtca
    10741 ctgtccttaa agtctttagt agactttccg ttgattacca tatcaccgga atcataatta
    10801 tctagtccac caatcacatt cagcatagtc gttttaccag aaccactagg acctaaaatc
    10861 gctacgaatt ctttttgtct gaaagcgaca gacacaccat ccaatgcttt ggtggtggtt
    10921 tcgccgactt tataatattt ttttatatct tttaattgaa gcataatcac ccttctcccg
    10981 tattgaaata ttcggtatac taataagtat atcagaacaa tgatcgtagt atacgaaata
    11041 aatgttaact gaagatgaac tacaagaaaa aatctagaaa tttttcaaaa aacagaggga
    11101 gatcaatgaa tcgtatttta gtagtagaag atgatccgca attacagttg ctttaccgtt
    11161 ctgtgttgga acgagcgggc ttttcagtca tcaccgcatt gaatggagag gatgcgctga
    11221 aaaaactaga agcgacacgt atagaattaa tcattacaga tatcatgatg ccgaaaatgg
    11281 atggctatga cttgctagac tcattacgta gcaccagatt tgacacacct gttctaatga
    11341 ttacggcaaa ggccgatttt gaggataaga aacgcgggtt caaattagga gcagatgatt
    11401 atatgacaaa acccatcgat gtcaatgaga tgatcctacg tgtggaagca ttgcttcgac
    11461 gttcaaagat caattacagc agtagcttga taatcggaca aacaaaatta gagctagatg
    11521 cttatacagt gttacaagat cagcattcgt tgattctgcc tcaaaaagaa tttctgcttc
    11581 tgtataaatt actgtcttat cccaacaaga tcttcactcg ccaacagttg atggatgata
    11641 tttggggatt agatacgaat acagaagaac gaacgatcga tgtacatatc aaacgtttaa
    11701 ggacccgttt tgaaaagacg gaagattttc aaatcatcac agtacgggga ctaggctata
    11761 aggcggttat ttaaagatga aaaaaaagct attttcacaa ttatggatct attttgctag
    11821 tattgtcttc atttcgatct tagtgacact gctgtgtttt ctcggtttta ttttcttatt
    11881 gtctcgacat tctatctcgc ctgctgaatc ggctggaaaa ccaacgttat acccgttatt
    11941 cgtctttgcg gggttcagta tggtcgtggg tacaggaata tcgatttttg ttgggcggcg
    12001 tatcctgcat ccaatcagtg cgctagggac aaatatgagt ctggtagcaa cgggagattt
    12061 ttcgattcga atggatgaac agcagaaagt agcagaagta cagcaactgt ataaagattt
    12121 caacgttatg gtccaagaac tcaatagtat cgagacactg aggaatgact ttgtgtccag
    12181 tgtatcccat gaattcaaaa caccactagc aacaatccaa ggatatgttc aattgttaca
    12241 agccccaaat ctctctgacg aagaacgcca aatattttta tatcggatta tcgaaagtat
    12301 cacgcagctt tcacaattaa cagagaacat cttaaaattg aacaaactgg aaaaccagcg
    12361 tatccaactg gaaaagaaag agtatcgatt agatgaacaa atcagagaag taatcgtttt
    12421 ttttcagcct aaatgggaga aagaacagct agaattggat atcgaacttg ctgcagtaaa
    12481 ttacacaggc aatgaagagt ttttgtacca agtgtggctg aatatcatgg ataacgccat
    12541 aaagtacaat caaatcaatg gacagattca tatcaaacta tttgagacag ccacagagat
    12601 tgtactggaa gtgaccgatt caggtgtagg aatgaatgaa gagaccagag atcgaatgtt
    12661 tgaaaaattt tatcaaggag atacaagtcg tcaaatttct gggaatgggc taggactttc
    12721 actggttaaa aaaattctag aactgcatga tggacgtatt gattatagca gtatcgaagg
    12781 agtaggaacg acagcaatga tacggttaag taaacaatag gaaaaagaat aaaaccccta
    12841 aaaattctat tgaaggtttt taggggtttt tagtcgtttt tttgtgatta gggaaatgtt
    12901 cttacggttc ttttggcata aaaatcgctg ctttcttatt gaactacgag aaatgttaga
    12961 ggtgtcattg aaacaaggac atgatgcaag aaagagagcg aaagtcatgc gtcgctctct
    13021 ttttttgggt ggatagatgg acagaaaatg tagggcttag ttttcttctt gatttaaata
    13081 ctcccaaaat gtatctgaag ccaaagaatg ctcaccgact ttacgagtaa atgcaagata
    13141 actctctgtt gttggagaaa tagggagaat cacagtattt tcttttaata gattcttgac
    13201 tgttttttcc ataacaatag caatccccat gtcatttgca atcatattga tgatcaagtc
    13261 gattcttgct cctttataag agatttttgg ttcaaatcca gcttcgcgac acagatctag
    13321 tacaggttga tacaagttcg tagtggggcc aaggagcaaa aagttctcct ttttcagttc
    13381 gcttagatcc aatttctttt tactagctaa aggatgattt ttaggtagaa ctgctacaaa
    13441 atcgtctgtt tcagtaggca accactcaat cgaacttggt ggggcctgga aacttctagc
    13501 aaagtggatc gtgtcactat gttcattggc gtcattgtaa gttaattcga cactttccac
    13561 ttctttcaac tggactgtaa attcaggatg gcgtttcaaa aactcggtga ttttggaaaa
    13621 acctttataa ttgatcattg tcggtatcgt taagatattt aatgaaagat tgttgtcttt
    13681 cgtataggtt tcaagcactt cttgcatagc atggtattgt tctacgacat tttttacata
    13741 tgggagcaat aagcttccag cttcggtcaa ttcgattttt ctatgggcgc gttcgaataa
    13801 tttgacgtct aattctgttt ctaacgaaag aatctgttta gaaatatttc cttgggtggt
    13861 gaattgtcga tcagcagttt tggtgaaatt cattgtttcg gctaaatcaa gaaaaacttc
    13921 gaatttatgg atatccatca tattcctcct acttattcca ataaagaata ctttaacaca
    13981 aaaaatgaat tggtgtaatc ttctctgtct gttacaatct ttcttgcagc gaaagcaata
    14041 attacagaaa tttttctgat ttttttcgct tcgtagaaaa agagaggagt tttttgatgc
    14101 caactggagt tttgatcaat gtaggttccg ttttgtttgg cggactaatt ggcggattag
    14161 taggaaataa attaagtgaa cattttaaag cacagctgac gatggttttt ggtgtgtgtt
    14221 cgatggggat gggaatctat tccattgcgc cgatgaaaaa tatgccggct gttatttttg
    14281 ctttagtgat aggaacagcg attggtttga ttgttcattt aggtaatggg ataaataagg
    14341 gggctgcgct gatgcaagta cctatttcta aaatcttccc tagtgaaaag cttggtatga
    14401 cccacgatga atttatcagc acattagtga cggtcattgt tctattttgt gcaagtggta
    14461 cggggatcta tggaagttta gattctggga tgacaggaga cagtacgatt ttgatttcta
    14521 aatctgtcct tgattttttc acagcagcta tttttgcgtg taatttaggg tatgtcgttt
    14581 ctgtgatagc aattccccaa ttcattattt tttatatttt gttcttattg gcaaaattta
    14641 tttatccatt gactacacca gacatgatct tagattttaa agcttgcggc ggattcttga
    14701 tggtcgctac cggttttaga atgatcaacg tgaaaatgtt cccagtagct gacatgatac
    14761 ctgcaatgat cgttatcatg ccactgagct ggatgtggac aaattggatt atgccactgt
    14821 tataataaaa atcaaagaga agccattttt tgctgactaa aaaggatcaa atcttttagt
    14881 cagttttttt gtatttgaca aactgatttt gaaactatat tatatgttgt ataatataga
    14941 ttgaaataaa atattacact tgagaataga aggtgacgta atgcacatcc agattccaac
    15001 tgttcttctt gatggtactg tgctagcagc attaagcaag gaagatatgt atgggtatgc
    15061 cttaacaaaa atcgtacaag aaagtctctc tgtcagtgaa tctacactat atccggtttt
    15121 gagaagattg aaaaaagaag gatatcttga gacctatgat gaaccttttg aaggcagaaa
    15181 ccgtcgatat tactcgttga caccaatggg aagtcgtcat ttagaagaaa ttattgatga
    15241 atggattgtt tttcgagatt ctttagaccg gttattggag gagagcacaa atgaatgaat
    15301 atttgaatga agttgtggat catcttcaag aaattcctga agacgatcgt tttgatttga
    15361 tccagtatta tgaggaatat tttttagatt ctggaaaaac attagatcag atcattgatg
    15421 aatatggtac accaaagcag tttgccttaa aattaaaaat cagttacttt tcagaagaag
    15481 aacaagcaga aaacgagtta gtgaaaaatc caaaaagaca aattcgcctg atttggttaa
    15541 tcattatcgg tttatttgct tctcctgtcc tcattccact agcactgggg tttatattgg
    15601 ttattggggg actattggtt gctttactag cgctcatttt tagtatctat gttttatgta
    15661 tcagtatctt aggtgttggc ctattcatga tcatctcagg aatcagtgtg tttggacaat
    15721 cgattctgag tggattattc tttatcggtg tcggtctgtt cgccacagga agcgcagtat
    15781 ttatttcgcc actgttgctg aaaggaacaa aagggctttt ttatgtcatg atgaactttg
    15841 ttaaatggat gggacgacgt tttattacaa aaagagatct gcattcagcg ggcgtttgaa
    15901 ggaggacaca taaattgaga ttgaaacatt ttttgattac cggtattggt ctgatgctta
    15961 ctggtggcct cctagcaggt gcaacttata cattaggcgc tcaaaagagt ctgacttggg
    16021 ataatggtcc tcggttgatc gatatggtta ctgagacaaa aaaaatcaag gatgcaaaca
    16081 aaatcgtcat ccatgcagaa aatcaaacag tttcggtcat acgcggattg gattttgaga
    16141 taaaaacgac ttatgataag acagaaaagc cagaaataaa ggagaaaaat ggcgtgttga
    16201 ctgtgaatgc agtcaaaaaa tcaacaggtg caatcattag tttagaagac acaagtgcac
    16261 aaatcactat tgttgtccct gcagatcatg aattatctga attgacaatc gaagggaata
    16321 atagtgcaat tgatatcaac gaagtatcaa tcaaaaaagt gaatactaag acacatgatg
    16381 gctgggtatc gttcaatgaa tttacaggag gaacaataac tgcgaaagat gaattaggct
    16441 cacttcgatt agatgaggcc aatgtggata acttgatcgt cacaggtgaa aacagcaact
    16501 tccatctaga agacagtttg atcagcaaag aaggaaaagt catcctaaac ggtggcaatt
    16561 tatctttgca tgagatggaa aacagtggct atactatcca aacgtctggt gaatcttata
    16621 ttgaaaaaga ctaccagcca ataacaaata ctttgttaga acaaggacag aaaaagctaa
    16681 agatcactgc taaagacaca tcgatcaata ttacgacgga tcaagaggac aatgaaacag
    16741 attgatcctg tactcaactg gatattttaa gaaaaaacag caaagatcct tccaatcttt
    16801 gctgtttttc atcgcttaac gcacataact atagtaaaat aagaaagaaa atatctaaaa
    16861 agaaaacagg gtgaaagagt atatgaaggt agaagaaggt caaagagaaa agttaaaaac
    16921 agaaatggaa agattacata cttatatcac tcaactaagc caaaccttct atgatccaga
    16981 caaagaaaaa gtgatggtta attacccgaa caattcagaa ggtcgccaat tagagcaagt
    17041 gtaccatgaa gttttcaaac atttattgac ggtgaagaaa gagctggatt attattcttt
    17101 accgattatc gatacaggaa tattgaagta tgatgggaag aaggaacgat ttatctttaa
    17161 atctgttcgg gaagatttgc ctctttcagc agggatggat ctagaggtct tggtagaaga
    17221 ctattttaca gaagaaaagc actgggttcg aacaaaattg gattatttac cgcaggcagc
    17281 cggagggaca caggcaagcg gttggtacat cactgaagac aaagagttag aactagaagg
    17341 tgtaatggcg cgtattcgaa aaaaaaatta aaaaagtaac attagatatt tattgaagga
    17401 taaaggagcg caggaagtag catgagagaa aaaagagcat tttatatcaa tggttatgca
    17461 gggattgtcg gattggtcgt attagcttta gttggattgt ttttcttcta tttaggtatg
    17521 tggcaagcga aagtttgggc acttttttta agtatttttc tttggttgat cacgttattg
    17581 ttgttaagtt cggcaactgt agtcagtcct aatcaagcaa aagtaatttt gttttttgga
    17641 caatatttag gtacgattcg agaaaatggc tttttcctta cgataccttt ggcacaaaaa
    17701 atgactgttt cgttgaaagt tcggaatttc aatagttctg ttttaaaagt caatgatttg
    17761 gatggaaacc ccatcgaaat ctcagcagta gtagtcttta aagtcgttga tacagcaaag
    17821 gcattattcg atgtagcgta ttatcaagat tttgtagaaa tccaaagtga gacagccatt
    17881 cggcatatcg ctagccaata cccgtatgat acattcaatg agaatgattt gacgcttcga
    17941 ggaaacacga cggcagtgtc tgacgagttg caaaaagagc tgcaagagcg tttagcagta
    18001 gcaggtgtcg aagtaatcga aacacgcttg aaccatttag cctatgcaac agaaatcgct
    18061 agtgccatgc tccaacgtca acaagcaaaa gccattttgt ctgctcgaca aaccattgtt
    18121 gaaggagctg tcacaatcac tcaaatggcc ttagagcaaa tcgaagatgg acaagaaatc
    18181 aatttcaccg atgatcggaa agtccaattg atcaataatt tacttgtctc aatcattaca
    18241 gacaaaggaa cgcaacctgt tatcaataca ggcgacatga aagaccgtaa gtgacatact
    18301 ttttgtaaga taggaagaag gagtttagga cggattattg tcttgaactc tttttttagt
    18361 tgttttaaag aaaatgacaa aattgaaaga agaatgatag ttgattcgaa ggcagaattg
    18421 ttcgcttttt tctataatca gtatataaag taagagagaa ggggaaaaag tgaaaaaact
    18481 tctgatcggt ctacttgttt tcatcgttgt ggtacttgca ggggtgaaaa tcgcagatta
    18541 cgtagttatg ggtggagaag aatactatgt acaaattacg acagatggta caaaaacagt
    18601 ttcaaaatca gactctggac aagaaacagt caactataga tatatcctgc ctggctatac
    18661 gaaagagggt aaggaaaaag aactggactt caagggacaa ttgactcgac cgcttcgtaa
    18721 aggagcatat ttaaaaatca cctggaacaa aaataaaggt gtcacttcgt atgaagaagt
    18781 cgaaaaaaaa gacgtgccga aaacagcact ggaaaaacta attaaagggt agggaaagaa
    18841 atgaacaaaa tagtcgaagt acagaatgta acaaaagtat acggaaaaaa caatgagaaa
    18901 aagacgcaag cattaagcgg catcagcttc gatgtagaaa aaggcgaatt tattgggatc
    18961 atgggcgctt ctggttctgg taagtcgaca cttttgaata ttttatccac attagataaa
    19021 ccaacagatg ggcatatccg aatcaatcaa aaagatgtga ccacattaaa aggaaatcaa
    19081 ctagcagatt ttcgtgcgaa tgagattggc tttattttcc aagatttcaa tttattagaa
    19141 agcttgacag cacaagaaaa tatcgctgtt cctctttctt tacaaggcgt cagaccaaaa
    19201 gaaatcaagc aacgtgtcca aaaaattgca gaacgtttat ccatctctca tattttggaa
    19261 agctatcctt ctgagatttc cggtggacaa aaacaacggg tcgccgccgc acgtgcattg
    19321 atcacacaac caacgattct attaggggat gagcctacag gtgcgctgga ttccaaaagt
    19381 gcccgggatc ttttagatac gatggacgaa ttgaatacaa aagatcatgt atcgattctt
    19441 cttgtgacgc atgatccgtt ttctgcaagt tattgccaac gtattttatt catcaaggat
    19501 ggcggtatcc atcaagaagt gaaacgtgga gatcaaagcc gtgattcctt ctatcgagaa
    19561 atactatcta ttcttggaaa cttggaacag tagggggaga ttgactatgc tttggaaatt
    19621 atcacttact gggatcaaga gccgtttaag agactacttg gtgttattct caggattagt
    19681 tatggcatct gctatttttt acatgtttga atcaatggca agcaacgaag cttttttgaa
    19741 aagtaatacg atcgttgcgg ctacagttat cattttccga ttcggttctg ttttactagg
    19801 gatcatcaca ttcgtttata ttttatatgc aaattccttt ttgatgacga tgcggcaaaa
    19861 agactatgca atgtttatga tgctgggagc aaaaggcaga aaaatcgcac agatgatttt
    19921 ttctgaaaca ttcttagtag ggatcgcagc tactttagtg ggttcagctg tcggtgtagg
    19981 attgacaagt atcgtccacc gattattagt ggatcagtta gatctcaata tttcgcattt
    20041 tacacctttt agtattcacg ggttgttgat cactgttttg ttttttgctg ttttgttttt
    20101 attagctgct gttgtcaatg ctttttcgat tgtcaaaaaa ccgattttag cattgattcg
    20161 tgcggatcag acaccaacaa gaatcaagca gcataaattc ttgtttttcc ttgaagtagt
    20221 actgggaatt gcttttctag gctgcggtta ctatatgatg aaacacgtgg ggacctatca
    20281 agtctttggt ataggggtag ccttagttac gatcgtatta ggaacttatt tcattttcca
    20341 ttctgtgatc attttctttt tatcattact aaagaaatca gaacagattt cattgaaaaa
    20401 attgaacaat ttcacattgt cacagttaaa ctttcgtatt cgtgaatata cacaaatgct
    20461 ctcaatggtc gctatgctgt ttgccttggc actgggcgct ttgacggtag gattaggttt
    20521 taaaaatgaa attgcagact tgacagaaaa caattctgga tatgatctag tgatgaataa
    20581 tcctcgggca gaagatcagc aaaaaatcaa agaactttca ccaacacttt ctgcttctta
    20641 tactcaaaaa gaagatgcgg gaacgattta ctataatgca agtgaatttg cggctcaacc
    20701 attgatcatg ataaaacatg aagatggaac accgccgaag atcacgaaag aaaaagttcc
    20761 tgctaaaaaa atgaatgaac tgactgtaca agaggaactt cgaagctatg aattgccgga
    20821 acagcaagaa aaagaaatca aggtagtcag tcaatcagaa tttgatcaac tgaacttgcc
    20881 acaatccact ttacagctag ttcaggtaaa agacttccaa gcaaacctga aaccaatcga
    20941 aacacttgtt gctcaaaata aaatgaacaa tccatctttg caaaaagtag agtacagcaa
    21001 ccagaaatat gaaatgtatg aagtgtataa tggtctattc tctggttttg aatttatggg
    21061 attcttccta ggtttagctt tcttgaccat gcttgctagc tgtttgatgt tcaagatctt
    21121 gtcaggaagc aagagtgaca ttgctcgtta tgaaatgctt gaaaagatag gaacacgacg
    21181 cgggttgctt aaacaatcga tccgtagaga agtaggcgtg ttattcttag caccaggaat
    21241 cttaggtgta gtccatgtct tattcggatt acaaatgttt ggtctattca tgcaaaatcc
    21301 atacaaagat atttgggttc cgtttacgat attcttcgta ttgtatttca tctactatgt
    21361 actgacgaca tggttatata ctggaatcgt attgaaaaag agattgtgaa aaagctgtcc
    21421 tgcatcaagt aataagaaca gccaagcaaa aatagctcct catatttttc gtttggttgg
    21481 gcttattacc gcagatgcaa gcttttgaac accgtttgtt cggaaaaaga ggttgtgaca
    21541 atatttttgt cacaaccttt ttttcacggt cttttattag aatatagtaa attttttctc
    21601 gttactcacg gaataagctg ttaagaaaac ggtttccatg tatactggaa tcagtgcaaa
    21661 tgaaagaaaa gagggtgcaa ggaacatgga aatcaatgaa caaaattttg gcgaaaacta
    21721 tcacttgatt acgatcacga atcaaaatgg gacatctttg tctgtcagtg atcttggggc
    21781 acgggttgtt cattttcaaa caataatcga taatgaaaaa cgagagttga tcttaggttt
    21841 tgatgaagca aaagaatatc tagaaaaaga cccttatatc ggtgcttcaa tcggacgtat
    21901 ggctggacgg attacgaatg gcacattcaa attagatgat gaaacgttcg aagtaaaaac
    21961 agacccggac actggtcatt gtttacatgg tggtgcacct agctttgaag ccaagcagtg
    22021 gcattataca gtcatcaatg gtgaaaacga agcatcggtc attttctatc agactagccc
    22081 agatatggaa aacggatttc ctggaacttt agatgtagaa gtacggtata cgctgacgaa
    22141 cgatgataca tggcgagtga cggtccaagg gatcagtgac cgcaaaacag tattcaatcc
    22201 tacaaatcat gtctatttca atttaaccgg tgatccagca cagtcaatcg acgaacatat
    22261 actttggttg aatagccgat tatttgctac gctcaataaa gatacaacgc ctacaggaga
    22321 agtagtttca gtaagtggca cagcatttga cttccaacgt cctaaaaaat taggtgaggt
    22381 ctttgccagt gattttcgcc aatcaatgat agtgggcggc atcgatcatc catttttgtt
    22441 gaaaaaacaa tctggtttac taaatgctgc ggaattgaca agcccagatg aaaaagtatc
    22501 gatccaagta aaaacagatg cttcaggaat cgtgattttt acagcaaatt ttggagaaga
    22561 tggaccggaa atgcgcggga ataaattagt aaatcatggc ggtatcacat ttgagactca
    22621 agaactgcca ggagcggagc gacttgaaag ttttggagat gtcactctgg aacctaacca
    22681 agtacgcgag tttgtaacgg aatacaaaat aaatataaag aaatagaata aattaaaaag
    22741 ggagtgtgac agtgtcacat ccccttttta atttattcta tttctttaaa ggcagatcaa
    22801 gccagaatga tttgtctaaa cttaacaagg ttagtacagg aacagttgca gctttaactg
    22861 tacgagtagt tgtttctggt atctgtcttg ccgtaaaatt gttccacaaa tcccagattg
    22921 aagcgacacg gaagatggaa gaagcgttgt tgacgcgttt tatcgttgaa aattctaatc
    22981 ctgtgattgg cacgccatct gttgtccatt tgattggcac atcgaatcgc ttagacatat
    23041 tgaggatttc agcgtttgct tcttcagttg ttgctgcttc ttttttcggt tcatcatatt
    23101 ttgtcaggtc gtacgcttcg atgatcgcgt tcaatttttg tgaatattgg cgatctgtag
    23161 cataacgtcc ttccaaatat ttggttgctt ctttgtagtc ttttgtttcc gacttccaag
    23221 ttggtttgta gaaatcagga ttgccagtca gtccattttt gatcaagtcg gcatagtctt
    23281 ccaaactttc cttgtaagaa ggatatttac ggaattgtgc gcggatttgg tagctttgtc
    23341 cggaactatc ttgttcaagt gtattgaagg tcacgctgct tcctttatat gatcctttga
    23401 taccaaaaag gttatgattt ggttcgcttg ataataagct gtttccagat ccactttcaa
    23461 ggatagcttg agccatcatg actgatgcgt agattccttc tttttgcccg atttcctgtg
    23521 catcatctgc aatctttttc aagaactgat cagttgtttg gttttgactg aaatggaacg
    23581 agccatctaa tccatctaaa atagatgagc cgcctgtcag cgaacctgaa gcagcaggta
    23641 aacctgctaa gtttactcgg acagcaaaat caggcgtgaa atctgaaata gaagttactc
    23701 gaactttatc tcctggttga ggcgcatgga taaattgtcc gttcccaata tagataccta
    23761 catggtgagt aacaccggaa gaaggtcccc agaagacgag gtcgccaggt tgggcctgac
    23821 ttactggaat ctgcgtacct gcatattgct gttcgcctgt ccagccaccg atataatgac
    23881 cggttgcttt catatatacg taataagtca aaccagaaca gtcaaaagta tttggacctt
    23941 ttgctcccca tacatatggt tttccaagat gcttgaatgc ttctcgaacg attgcttgtt
    24001 ggacattcgt tgtatttgta ggcaatacag catcaattgg tgattttaca acaaaatcag
    24061 aagaagcaga agatggattc tctataccgc tttgatttgc tgtatttgga cgagatgaag
    24121 cattgttcgt tccgccattc gatgaaccat tgtttggatg gtttggttct ctctgagtat
    24181 ttccattgtt attcgatcca gatgggtttg tttgattcga agaattcccg ctgttcgaat
    24241 tattgttatt attgtttgaa ttatttgaac cattattatt gttgttatta cccacatctg
    24301 gtttgtttgg cgtttccgga tctggtgtac tagggacttc ttcactagga tcagttggtt
    24361 tctctgttga agtatccggt ccagctttaa attctgcagt aatagataaa ttgttcgtac
    24421 ctactgtaaa ggtctttgca tcataattta cttctttggc accattaaca gcgactgaag
    24481 caatttgttc accttcagct ggcgtaatag tgtaagttac cttcgtttcc gctaataaac
    24541 cttctaccgt tccactttcc gtaatatcca aaggttgctg ttcaggggaa tccgctgtcg
    24601 aagcagtcag ttggatctta ccaatcaaag aaggagcaat tgtaagggaa tatgtctcgg
    24661 ctggcttttc attttctgat ggatcagccg gatcaatttc agttggctcg gtcgatcctg
    24721 ttgttgagtt agttgttcca gttgggtctt ctgtaaaaga atccgttgtt tcactagtag
    24781 ctgagctgga tgtagtcgta tctgttgtga ctgtttgatc agctatttga ttatctacgg
    24841 caaatacggt attggtcgac aaaacagacg gagcaatcag ccaagtagca gctagcaaac
    24901 gtatcgtttt tttatttttc ataataaact agtccttttc ctttcattga ttttctgtct
    24961 tattcagcat tcattagaca ttttttggaa cagataatcg tgtcgaaaag ctttttcttt
    25021 tcataaatct gtctgtgtat tctaaataaa acaatttgta aataagcaac gagcattcat
    25081 tcgtttttct ttgacgttca ttttattgca tagaccacct ttgtttgggg ataaacaagt
    25141 ggggataaaa atggttatgc atatgtaaat tataccaaag tttggaaagt atcacaaaaa
    25201 tttataaaaa taatgatcct aaaaagaaaa agactgaaat atgtgataaa catctcatac
    25261 ttcagtcttt ttcattaact attcataaga cattaggtct tcatcaaacc cgctaacgag
    25321 agtagtgatc attgctacga ctagactaac agccagtcct gctaagtacc agaaaaaagt
    25381 accggaaatg aatgcaggca atgtggtcag actaccaaat acaaaagcga tcgctttcac
    25441 ttgggcaaat cccattacag ctccaccagc agctgcacca atgcaagcag caacaaatgg
    25501 ttttttcaat gggatcgcaa ttccgtaaac agttggttcg gtcactcccg caagtaaaat
    25561 cgaagcaaaa gcagaaccgg agatcgaacg ggtttttgaa cgtttacttc gcagaaatac
    25621 acctaaagct gcaccagcca ttccaaaatt ggctgctcct gtcaacggaa cgattcggtc
    25681 gaacccataa gcagagatat tactgatcat gacagggttt acagcccatt ggataccaaa
    25741 tattaccaaa atattccaac caccagcgat gattgcgcca ctgatcggtc cgttaatatc
    25801 catcatccaa gtaattgcgg cagctaaacc ttcgccaagg taaacacccg caggcccgaa
    25861 taccattaac gtcaaaggaa ccgtgataac taatgaaagt aaaggtacaa atactaattg
    25921 catattttcg cgaatatatt ttttgaggaa tttttcaaca aaagaataaa agaaaatacc
    25981 taaaatcgcc ggcatgacag tagacgtata ctgcatcagt actacaggaa tccccagaaa
    26041 atcagtagct gctttgccac tgtctgaaag taaagaggtc agattcggtt caatcagtgc
    26101 tgcagcaatg acagccgcaa tatatccatt cactttaaac gttttggcag cagaaaaagc
    26161 aagaaagatt ggcagaaaat aaaagacggc attcgacgca gcagacaaaa tatgataagt
    26221 tccgcttgtt tcactaagcc agccaatcgt agtcgctaaa acaaccagac cttttaatat
    26281 accagaaccg gcaaacagcg gaatgatcgg cgtaaagatt tccgatatca aaccaaatag
    26341 tttttcgatc ggatttagct tttctttcgg agctgaatga tcgatttgac gcgtcaattc
    26401 cttgtaagca ggagccaatc cctgatccat gattatttct gcatatctat cgagtaaaat
    26461 gaaatactta atggaaggga tttgctgttt taatttttct gcattggcta ctggctgttt
    26521 tttcaatttg atacgaagcc gagtcgcaca tggaaggaca gaatcaatat tgtcttttcc
    26581 tcccaactgt tcaatcagca tatgaatctg ctcggacagt accatctgtt caggattcat
    26641 tgtcgtttcc attagaagac cactccactc actaatataa tattggcgta aggtgtcatt
    26701 tcgcctgtac gaataaatgc atgacagtta ttcaactctt ttttcatttc ttcatgtggg
    26761 ataaagctaa tcggtgtatc tggtaacaat aatttgattt tttccaatat ttccgggttc
    26821 attgtcttta tttcttccgc caattcaatc gattgtacct caagttcttc taaaacgttt
    26881 tctaaaacag ataaaaaact tggaagaccg tttgagacag ccaaatctat tttttcagta
    26941 ccaaagggga caggcatgcc tgcatccccg atacttaatt tatcaaagtg ccccatttgt
    27001 gcgattactc gtgaaatatc tgaattgatt acttttcctt ttttcatgtt tgtttcttcc
    27061 tctcattgtt aattttagac tgctgattgt tctaaagctt cgcggtaagg gatagaaggt
    27121 tgcgcaccat aagactgcac agcaacagaa gaggctagat ttccataaag gatcgcttct
    27181 ttcaagttac taaggtctgg ctgaagtgtg ctgcttaatg cgccaataaa tgtatcacct
    27241 gcggctgttg tgtcaacggc atccacttta aaagcaggga cgataccgtg ttctttttct
    27301 gtatgataga aagcgccggc actgcctagt gtaatgatta ctgttccaat acctaattca
    27361 tggagttttt cggctgctgc gaccaaactg ttatgatctg tcactctgat tcctgtaatg
    27421 atttctgttt ctgtttcatt tggtataatg atatctgtct tttcaagtag ttcagtagga
    27481 atcgtttcac gagctggtgc aggattcagg atcgttgttt ttcctgcgtc ttttgcaata
    27541 gaaaaagcta ggatcgtcgc atctaagcta ctttcaaact gagcaataat aaagtcactg
    27601 tttgtaatca gttgcttgtt ttttaggact tcttgttcat ggaaagcatt atttgcccct
    27661 gcatggatca agatactatt ttctcctgct gcgtctacca taatcattgc ttgtccggtt
    27721 gtggcgcctt ggatttcagc tatcccagat gtatcgatgt tttcttttgt cagtagatct
    27781 aataactgtt gtccttcgct gtcagcccca acgcctccaa taaaagatgt ccgtgcgcct
    27841 gaacgtttgg ctgccactgc ttggttggca cctttacctc cgccagcgtg aaaaatctca
    27901 tgcgcatgca tcgtttcgcc tggcttgggc atgttggtta aacgaagggt agtgtccata
    27961 ttaatacttc caattactgt aaccgtgttc attttacaaa cctccaacta tctcatttat
    28021 tttgatggga aaattatttt ttaaaacgtt ttagtaaaac gttttaatag ttcgataaaa
    28081 atatagcaca ccttgaaagc tatttcaagg gtgcagttga aaatcttttt tctaatcgta
    28141 caggtaatct tttttcttcc cattcttttt ctgggaattg gatccgatct aacaataact
    28201 tggcagatgt ttgtcccaat tcgaagattg gttgtgcgat cgttgtcagt ttcggcttga
    28261 tatactcgca catatctata ttatcatagc caataatgct gtagtcttca gggatgcttt
    28321 ttccagcttc ctctaatccg cgatataatc caaaagctaa ttcatcattt aaagcaaaca
    28381 caccagttgc agcagaatca agaagttctg ctgtgatctg gtagccacct tgttttgaga
    28441 actgtgtagg taagaggatc agttggtcgt gagggatttg gtaaacatca agagcagatt
    28501 taaacccctc aatccgagcg tggacatttt ccggtggatt ttcaggatag acaagggcga
    28561 tcgtttgatg tcctagacta agcaagtgca tgcccgctag gtaaccaccg cgaaaatcgt
    28621 ctgttcgtac ggcatcacta aatccttcag attttttctg atccaaaaca atgaagggcc
    28681 ggccttgttt tttcaaattt tcgttgattg catctgtaga gacagcagaa gtcgcgataa
    28741 tgaatccatc cacacctcga cgtgtgagct cggctagata ttcgatttct ttttgatgat
    28801 cagaatcagc attacataat atcgtgacga aattctgctt atacaagata tcctcaattc
    28861 ctcgcatcag tgtactgaag aatggattcg tgatatcagg aacgagtaca ccaattgttt
    28921 tcgtttcctt ggtaatcatt tgtctagcaa aatagtcagg ctgatagcct aattcttctt
    28981 tggcagctaa aactttctga acagttttcg gactgaattt ctccgtattt ccatttaata
    29041 tcaaggagac agttgtgatt gaaacgccgg aaagtttagc gacttctttg attgtgatct
    29101 tttttttcac catgttcata ctcctatcta aatcctgtgg ttattttccc atgaaatcaa
    29161 aaagaagtaa atgaaaatca cgtgtgccag tacttatttg ctttgttgga tagcttcgat
    29221 tatttgtttc gttgagcgta ctcgtgcagt tttcggaaat atctttttta tgaacaattg
    29281 atgggattct ttgtcacgat cactgcaagc atcttcagca agcacgatat ggtacccgtg
    29341 ttgaaaggca tctaatgcag tagcatatac accgtttgtt gtcgctacac cgcttaaaat
    29401 gatagtttcg attccacgcc ggcgaagttg aagatcaaga gaagtaccaa aaaaagcact
    29461 tggattgtat tttgtgatag tcaacatatt atctgtatct ttcaaagaat ccttcaaaag
    29521 taaatcagtg aattctggag gtacagaagc agtcattcca cccatatcag tttgttgact
    29581 caaataaggg aaagtggaga tgtctacgtt cactaaaact ttcaaggcag cggtacgttt
    29641 caatgttctt actaacaaat cattgtttgt cagaatagat gctgcagtgt gtggagagag
    29701 tgtaccgtta tttacgatct ctttttgcat gtcgatcgcg acaaaagcag tttttgataa
    29761 atcaaaaatc atattttcct ttaaatcatt catgatgttc cttctttcaa ataacaatgt
    29821 tttttatgta agtaaatcat aaatcgttta tttgtcaact aaattaaagg attcctttct
    29881 ttagtctaga gaaattcagt ggtaaaataa ataagtgtga gaaaacgcat tcgatgcata
    29941 gatatagcga gaaatatcgt gaaaatggag gaatcagagt gaagtatgtc gaagtaaaaa
    30001 atgaatacaa acgatacaaa atgggagaaa cgaccattac agcaaatgac gatatttctt
    30061 tttcaattga aaaaggcgaa ttagtgatta tacttggtcc aagtggagca ggaaagtcaa
    30121 cgattcttaa tattttaggt gggatggata cacctgatga aggtcagatc attattgatg
    30181 acacagatat tgcgcaattt tcagataaac agcttactgc ttaccgacga acagatgtag
    30241 ggttcgtttt ccaattctac aatctcgttc ctaatctaac agcaaaagaa aatgtggaat
    30301 tggcaacgga agtttctcct gatgcgcttg atcctgtaga ggtattgagg caagtgggcc
    30361 tagctcatcg attgaataac tttccgtccc aattatcagg aggcgaacag cagagggttt
    30421 caattgctcg tgcactagct aaaaatccca aacttctttt atgtgatgaa ccgacaggcg
    30481 cgctggattt tgaaacgggc aagcaagtat tgaaattatt gcaaaacgct agcagacaac
    30541 acggcaatac cgttttgatc attacacata attctgcttt agcgcccatc gctgatagag
    30601 tcattcacat taatgatgct aaagtaaggt ctgttgaatt aaatgatcat ccttcatcca
    30661 ttgatgagat tgtatggtag ggggatttta tgaaaacaag aacatatctt aaagcaggtt
    30721 ttcgcgaaat tcggcaatct aaaggacgat tcattgcaat catccttatt gtcatgctag
    30781 gaacactttt atttgtaggt gtcaaaactg ctggacctgt catgcaaaaa acgatggatc
    30841 actatgttgg tacagcagga ctttctgatt tgcaaatcgt ttctactggt ggcttgacac
    30901 aaaaagatat tgctcaagca gaaaagatcc cagatgcaaa agtagaaaca ggaaaacaga
    30961 tctattattc caatactggc aaaaacgaag tgattcaaat attttcttat aacaaaaata
    31021 acaagcagaa caagctacaa ttaactgatg gaaaactccc ggaaaaacca aaccagcttg
    31081 tattggatga aaaagcggaa gatgaagggt ataaaatcgg tgatatttat cagattgatt
    31141 cagatgaatt gaaagaaaaa gagtatacca tcacgggctt tgtccgttct ccattgttca
    31201 tcaacaattt ggagagagga tacgcgaacg tcggaaatgg tagcgtcgat tattttgtct
    31261 atttacctga atccgttttt aaaacagata tttattctgt cttatatctt gattttacaa
    31321 acgtaaagaa tttgaatacg tacagcaaag cttacaaaga taaaatggag caaaatcaag
    31381 aaaaggcaga aaagtattta caagatcgac ccgaagaacg cttagaagag ctgaaaaaat
    31441 cggccaacga agaattagaa ccggcacagc aaaaaatagc ggatggcaaa gcacaaacaa
    31501 cgcaagcaag aacacggtta gaagatgcta aaaaacagtt agcgcaacag tcagcaacta
    31561 tccagcagct tcctgaagcg caacgaacaa tcgctgttca aacattatct caacaagaag
    31621 ctcaacttgc tgaacaagaa aggcaattag ttgagaaaga acgtgaactg gcctctgcag
    31681 aggaagaatt gaatcgaaat gcagaaaaaa ttgaaaattt aactaaacca tcatacctat
    31741 acaatgaacg ttcagaaaat gtcggttttc aagaatttgg tgatctgtct gatcgtatcg
    31801 ctgcgattgc caatgttttt cctgttttct ttttctttat tgccgcattg atcaccttta
    31861 cgacaatgac acgtatggta gaagaaaacc gcagggaaat cgggacatta aaggcgttag
    31921 gttatacgaa agttgaaatc gcaaaaaaat atgcaatcta tgcaagtcta gcctcaggga
    31981 taggtattgt tttaggaacg atattaggaa cgaatctttt gccaaggatc atttttgagc
    32041 tgtctaacga gcggtatgat attgggagtg cgcttatttt ttatgactgg ccgccgattt
    32101 tacaagcagc tgccgcattc ttcattgccg catttggcgc tgcaatgatc gttttattca
    32161 aagatttaag agaacggcct gctgcattgc ttcaaccgaa agcaccgaag ccagggaaac
    32221 gcatttttct tgaatacatc actccgctgt ggtcacgcct tagctttaat caaaaaatca
    32281 gttaccgaaa tctcttccga tataagtcaa gaatgcttat ggcgattatc ggaattgctg
    32341 gatgtgccgg gctgatggtt gcaggcgtgg gattgaaaga ttctctaagt tctgtttcag
    32401 ccaaacaatt tggaccgatc attgactatc aagcaatcgt tacattggat tcatccacgg
    32461 aagatagtcg tcaaaaagca gcggatatgc tgcagaagca agaaaaagta aatgagatcc
    32521 tagctattca tactcaaacc gtagaattga gaaaaaaagg acatgcttcg caaagtctga
    32581 cagtgatcgt accaagtaaa acagctgatt tggatcgttt tatccattta actgatcttg
    32641 aagagaaccc acgctccttg cctaaaacag gaatcgctat tacgcaaaaa gtagcagaac
    32701 tatttgactt atctacagga gatcatattt cgctttatga tgaagatcaa aaagaatgga
    32761 aagtcgaagt aaaagaaatc gtgaaaaact atctaggtag ctttatttat atgtcccctg
    32821 aatattatgc ttcagttact gatcaatcga tgatggataa tgcatttttg ctgcgtacag
    32881 ataagatgac aacaaaagaa gaagaaatgc tttccgagaa actgcttgcc acagacgctg
    32941 tgacaaatac gtctttcatg tccaaacaaa tcgaaacgca agaagaatca atggcgaact
    33001 tagactcggt tgtcttaatc tttgtcgtat tatcaggact gctggctttt atcgtcttgt
    33061 ataatctaac taatatcaat atttccgagc gtgtacgcga attatctaca ataaaagtcc
    33121 ttggattttt tgataaagaa gtcacgatgt acattgttcg agaaaatatc atctttactc
    33181 ttttaggaat catcggagga tttggtgtag gatatatatt gactgacttc atcttgcaac
    33241 aagcgtctat ggagaatgtc atctttccat tagtgatcac atggtgggct tatgtcttat
    33301 cagcaggatt aactatcgta tttacggtta ttgtgatgat tgttacccat ttcaaattaa
    33361 agcatatcga tatgattgat gcgttgaaat cgaatgaata aaaacagagg ttgtgaaatc
    33421 agcggtttga cctgagtatt agagaaacaa acggcaaaat agtttttcat attttgccgt
    33481 tttttgagct aataccgaag gacagctgat tgaacaccat gaatcagagg ttgtaaaaaa
    33541 gccgtcctgc atcgagcaaa aagaatactc aaataaaatt agctcctcat gttttacatt
    33601 tgagaagact gattgccgta gataaaagct tttgaacacc atttatagaa gaaacaagaa
    33661 tattttgcta ttttaaacaa gaggatagac aaatacatgt ctgatctctt gttttttatt
    33721 gggcaacaga cctcttagaa tgtataaaga taaattttac aaacgctttc ggttcagtta
    33781 taataataaa tgataacttg tatatataag ttgtggtagg taataaatca gttgaatgga
    33841 ggtaaatatc catgacattt aaagacaaag tcatttacca aatctatccc aaatcttaca
    33901 aagacagtaa tggtgatgga attggagatt taaaaggaat caaagaaaaa ctcccgtatc
    33961 tgaatgatct aggcatcgac atgatttggc taaaccctat ttatccaagc cctcaaaaag
    34021 acaacggtta tgatatctct gattacacag ccatcgatcc tatctttggt acgatggagg
    34081 aattcgaaca gctaatagcc gaagcaaaga aataccggat agaaatcatg ctcgatatgg
    34141 tgctgaatca cgtttcgaca gaacatgaat ggttcaaaaa agcactagca ggggaccagc
    34201 attatcagga cttcttcatt ttaagagaag agccaacgga ttgggtatca aaatttggtg
    34261 gaagtgcttg gtcgccattt ggagatacgg ggaaatatta tttgcactta tatgatcgga
    34321 cacaagctga cttgaactgg cggaaccaag cagtaagaga ggaactattc aaagttgttc
    34381 gtttttggat ggaaaaaggg gtaaaaggat tccgtttcga tgttatcaat gttatcggta
    34441 aagacgaaca attgaaaaat aataaagaaa atgatggcaa acctgaatat acggacaaac
    34501 caatcaccca tacgtatcta aaagaattga accaagcaac gtttgggacg gattccacta
    34561 tcatcacagt cggtgaaatg agctctacga cgatcgaaaa ttgtatcttg tatacagaac
    34621 ctagtagaga agaattatca atggtcttta atttccatca tttgaaagtc gattatgaaa
    34681 atgggaataa atggtctact cctccatttg attttgcaga attaaagcga ctatttcata
    34741 catggggaga aaagatgagt gagggtaacg gctggaatgc tctatttttt aataatcatg
    34801 atcagccacg tgcgctcaat cgatttgtag ctatcgatca gtatcgaaaa caaggagcag
    34861 agatgctagc aaccatgatc catttgaacc gtgggacgcc ctatatttat atgggagaag
    34921 aaatcggcat gatcgaccca gactattcat cgatttccga ctatattgac gtagaaagtt
    34981 tgaatgctta taagttactc cttgaacaag gattcacaga aaaagaagcg tttcgtcgga
    35041 tcaaagcaaa atctcgcgat aactctcgaa cacccatgca atggtcagac acagaacaag
    35101 caggatttac tacagggaaa ccttggttaa aagttggagg caagctagaa gagattaatg
    35161 tagaaaaaga actatcttct gaagattcta ttttgtccta ttacaagaaa ttgattcggc
    35221 tgagaaaaac atatccaatc gttgcacaag gagattatca tgcttatgaa gcaaatcatc
    35281 cggaagttta tggctttctt cgccaatttg aaggacagca gctgcttgta ttaacaaatt
    35341 tctatgataa agatacaagg atcgccatcc cagaaggatt cacagaagcc aatattctta
    35401 tcgataatta ttccgatact gttcttcatc aaagtctgga gctaaaacca taccaggcaa
    35461 ttgctttgct gaaaaattaa aacaaaaaca caaaacgtcg ttcctacgag ctattctcgt
    35521 aagatcgacg ttttgtgttt tatttaaaat aatcttcttc agaaaatgaa gagttttcat
    35581 actctccttt atcgccataa aatttattgt agcgttgttt gaatttacgg aaaataaaag
    35641 taacgagtaa tttgactaac gtatagatag gaataccaaa aataacgccc acaattccca
    35701 ttagatcacc catgacaagt aaaacgatta agatcgtaat cggatggatc tgtaaacgat
    35761 cacccattac tcgaggaatc accaagtcac cgtggagaag ttgtacggca aaccagacaa
    35821 tgacaaattt gacagccata aaagtagagt cttggaatgc aatgatcaaa cctggaaaga
    35881 aggcgataaa cggcccaata tatggaatga tacataacaa cccagcagaa atagctaaaa
    35941 cactagcaaa ttctaatccg atcagtaaga aacaaaccca gtagactgct ccaaggataa
    36001 atgaagcaat gatttgcccc tttagaaatg aacccaattg ttgattagca atctttgtca
    36061 aatttttaaa atctgtacga aatgctggtg ggacaatcgc taaaactgac tgataaaatt
    36121 tttgaggatc tctcaaaagg aaaaaagcga caattggacc agtaaataaa gtaataaaaa
    36181 tagctgtaac agttgaaaaa atgttgctga tccgttgtgc gccactttcc caataatttc
    36241 caataaatcc agctatatca gacgtcacgt cgtcaataga agcgaaaaat tgattaaatg
    36301 aatcggcaaa aggtgttttc tccaaaaatt gtcggagact ctcttgaaaa tcttgaaaca
    36361 aatctggcaa actactgatc aatgtctttg cctgttcttc aagaaaagga ataagccata
    36421 tgcttccaag ccccaataaa aataaaataa tcacataaac gataatgact gacaagttcc
    36481 tcgaaaggtg cttgctcaaa cgtttgatga ctggttccaa aagataatac aagatcagtg
    36541 caaacaataa tgggggcaag atagtagcga taatgattcc gacaggcttg aatataaacg
    36601 agatctgatg gaaaaaataa atgatcagcg caagtaagat aactattcct aaaacatagt
    36661 aagaggtttt tcctcctaaa aagcggatca aacgattcgt tgtatctgtt tcttttttca
    36721 ctctttttcc tcctttatct ataaattcat tatagacaaa agcgggtata aaaggaaaat
    36781 gatagaggtt gattgcaaaa atatcgtcaa tcattcatat aaactttctc atcaattaaa
    36841 ataagaaaac gcttgacagt tcttttaacc atatgataaa ttaaatcctg ttgctaaaac
    36901 gtaactatta cggtttgcga aaagcgaatc ggaacattca aatgaaagaa gatgagaaga
    36961 ggagtgtcat aaatgaaacg attgataggt atattggcca tgctggtttt agcaggtatg
    37021 ttaactgctt gcggggcaag tgggaaagcc gaggacagta aagaaaaatt gagcgtgatg
    37081 acgacctttt atcccatgta tgattttaca aaagcaatcg tcggggatga aggagaagta
    37141 gagttattga ttccagcagg gactgattcc cacgattatg aaccttctgc taaagacatg
    37201 gcaaagatcc aagatacaga tatctttgtt tataatgatg aaaacatgga aacatgggtc
    37261 cccgcaatcc aaaaaacatt acaagaaggc aatgtccata cgataaaagc gacagaaggt
    37321 atgcttttac ttccgggaag tgaagaagga catgatcatg accatgaaca cggggaagaa
    37381 ggccatacac atgagctaga cccacatgta tggctagctc caagtttagc aatcaagcag
    37441 gtagcaaaca tacgtgatca gctgattgaa gcttacccag aaaaacagga agtatggaca
    37501 aaaaatgcag cagcctatac cgagaaactt caagcactcc atcagcttta tcaagaaacc
    37561 tttaagcaag caaaacaaag atcttttgtc acgcaacatg ctgcattcaa ctatctagcg
    37621 ttagaatatg gattgaatca agtatcgatt gctggtcttt cttctagtga agaaccgtct
    37681 gcggcgagaa ttgctgaact gaaacacttt gttaaagaac atggaatcaa ctatatttat
    37741 tttgaagaaa acgccaaaga tagtattgcc agaacgttag caaacgaagc aggtgtatct
    37801 ttagaagtat tgaatccttt ggaaggattg acgaatgaac aaatagaaaa tggagaaaac
    37861 tatctttcta tcatggaagc aaacctcgaa gcgttgaaaa aaacgacaga gacagaaaac
    37921 ccgctagaag atactttgac ccccaaaaaa gaaaagagcg tctacaacgg ttattttgaa
    37981 gacgaggatg tacaagatcg ctctctttca gattgggcag gaacttggca aacagtagat
    38041 acgtatgtag aagatgggac ttttgatcct gtttttgaat ataaagaaaa attgaatcag
    38101 gataagacag cacaagaata taaagaatat tatacgaagg gctatcaaac agatattgct
    38161 tcaatcaaga tcagtgagaa agagatggca tttacgttta agaatggaac aacgaaacgt
    38221 tcaaattatc gttatgtagg gaaagaaatc ttgacctacg aggcaggaaa ccgtggcgta
    38281 aggtatctat tcgaagcaga agataaggaa agtggcgctt ttagatatat tcaattcagt
    38341 gatcacacga ttgcaccggc tgactccgaa cattttcatt tatatgcagg aaatgaaagt
    38401 caagaagtat tgctgaaaga aatggagaat tggccaacat tttatccaga tacaatggat
    38461 ggacgtgaaa ttgcacagga aatgcttttg cactgatagg caaaaaagaa ccgaagggtt
    38521 tggatcggct ggtcatttag tcggtccaaa ctattcggtt ctttttatga aatcaatttc
    38581 tttaatccac ggatagaggc tgggatggtc tcgccgtttg ccaacgtgac ttctctggtt
    38641 tttttattaa tcgaccgcac attttgtgta ttgataacat aggatttatg acaacggata
    38701 aaattccgat gcattttctc gatttctttg atcttctcat agaattgtaa ttgggcatga
    38761 gtcaaatgga cttccagttt atgtggcgct cctagcgaag tagaaaaata ttggatgtct
    38821 ttgatcggta aaaatttgat ctcatcatta aactctattt tgaagatatc tttttggatt
    38881 tgggacattt gaaaatcttc gaaaattttg ctcaggatat gctcgacatt ttcttttaaa
    38941 tcataaagat cttctttgac gatataatca gtcggttcga tgttgctttt taagattttc
    39001 atcgacattt ccgtatggga agtcacatag attatttttc ctaaaggatc taattcacgg
    39061 atcaatttac cgatcgctac accatccatt tcactgtctt ctagttcgat atctaaaaag
    39121 taaataccaa aagaagaagt tctgatcttg gctgcattga gaagttcttc cggatcagag
    39181 gtagaaatat ggacataact gtctaagttt tcaatcatga ttctattttt gatcaccgtt
    39241 gataaaactt ctaattgttt tggatcgtct tcacaaatat aaatgggaat catatcatta
    39301 ctcctttatt ttatttgtat ataaatcgtt tgagaaaaac gctggttttc aattgatgtt
    39361 tcaaggaaaa gataaggatt ggtctttgtc aattcatcca agataaacaa gccaaggcct
    39421 tcgttttttg gatttgtttt tgttgagaac cctttttgtt tcaactggtt taacggtaat
    39481 gtatttgttg ttgtattgat cacacgaatc atcacggaat gattcttctt gagtatggtc
    39541 aattcgattt ttttcttctt tgcagcacta gctccttcaa tcgcattgtc caagataata
    39601 ccaagcatac gtacaaggtt taccgtatgt ttcgtatcca gttcgattgg ctcaggaaaa
    39661 tgaagctgga cgatcaaccc tttttcctgt gccatcatga gttttaatga cagtaaacta
    39721 cggatctcag gaactttcat attatccaac atacttagat tggccggaaa aaggttcatc
    39781 atctggcgtg taggtaatat cgtttgatca taataagacc gtaatccttc taagtcgcct
    39841 tctgaaatat agctgtgaag agaaaaaagc agattttggt aatcatgttt gaattctctc
    39901 aagtcttgat agtttttttc tagatctttg atataatcct gttgcatcct gacttgttgc
    39961 tctaataact gatcagctaa tttcttatta gagattttcc aataataaac caagatgatc
    40021 aggccaacac acagatatag aatgaaaaaa ctcgtattca aagctaagac atcaggtgtt
    40081 tcaccagaaa aacgggtata aaaaataatg atatagtatg taaataatat caatgtcccg
    40141 atcgtaccga tcatacggcg gtccacagtg tgaaaccaag tctctaacga tttttttaaa
    40201 caaaaagcta ataaagcaga taaaaaagcg gataagacaa tgtgaaaata ctgcaatgaa
    40261 tctcctggtt caataaccga agatttcaaa acaaaaaaat cgccgatgct tgttaagtga
    40321 tctcctaaaa gcgacgtcaa taacccaaaa ggaagcgcgt aaaccaattg ttgacgcgaa
    40381 gtcgaaaaga agaaaaaagt aagcatcagc attcctatag caattagagc agtaaaaatc
    40441 cctaaaatcg aatagaccca tccaatcaaa atacaagaaa tcagaatgac tcccgcaaac
    40501 agatatttgt atcggatgtg atggtcaatc aataagatac aaattgtgta aatcaaatat
    40561 tgcaacgcta tggaccataa aaacataaag tacagctccc attgattttt accaaattat
    40621 agcacaattg gcgtattatt tttttaattt ttcagggatt ttgaattcag aactcatacc
    40681 aaagcagcag ccagatacaa aaaagtcaga taagttagtt aattgtttaa tgattgtttt
    40741 tttcatgaaa gattcctcca aaattcatca agtagtttgt aataggaagc aacgtagcta
    40801 tttctaaaac aatcccaagt agcaaatagg tagaaaagta agaagctgag aaaaataacg
    40861 taatgagaga aaaaattaga aacatgctga tcgccttctt taataatggg ggacgtttct
    40921 cgggttcaat gggattgatt gctgtacctc ttgatccata gcgaagcagt aacaaaaagc
    40981 agctgattaa caaaaagacc atcattggga aggagatagt caattgcaga tgtttcatca
    41041 ccaagggaac gccccataaa taaagtagtg tccacagcag acaaacgaat tcagagtcgg
    41101 aatgcaatcc ataagcatat ctgcggatgc agatataaga aagaaaggtg attcctgttt
    41161 ccgcccatga gcctgtcacc agagaaaaga ctagaacgac cgctagtttt ccaagattat
    41221 tcaataaaac ttctaagaca aattttactt ggacatacac catatcttct tccgatttgt
    41281 ctccgctgaa taaggcttct aataatttgt tcacaacttt atctttcatc tcatacgtac
    41341 ctccaccaca aattttatgc taaaaaaaat aaaaaacgtc ttttgtttca taaaaagtgg
    41401 ttttgacatc aaaaccgtca tgatctccta aaaaaatctt cgttttccaa gaaccttacc
    41461 aaaaaaagtg acagttttga tacgaaaagt actttttatg acaaatttgt gctttttcga
    41521 gtgatttatg ttaaaaaatt actgacctta taaaaggtga tggagggatt cttatggaaa
    41581 atgaacaatt gtttgaagtc ggcgaaacat atgcatttaa atctgattta tttgaatcac
    41641 caataaaagg aaaaatagaa aaaatctatg aaaatagtgt gatgatacgt gtcatgaaat
    41701 gcgcagtaga agacaatgat accgctcata atctgcactg gcagttagtt gtacgcaaat
    41761 caagtacaat agaagaataa aaacagataa aatgttgaga gcataaagag gttgtgagtc
    41821 tcccgtttag ctctgagtta caaggaataa tgttaaaaaa cagcttttca tgttttatga
    41881 atattgcctt gtgaccgagg tgttggcagg agaatactgt ttatttgaaa aaagggctgc
    41941 gacaagactt ttgtcacagc ctttattttc atgaatagga gttacttttg gctactttta
    42001 gagaagtagc ttttaaggag cagataaagt caaggctttt atttctataa atgaagtagt
    42061 aaaatgaaga acagatttta ttacaggaag gatgccgata attgtgatca ttgttgcagg
    42121 aacgatcggt gcagggaaaa gcacactaac tgaaatgctt gcccaagatt tagaaacaaa
    42181 acctttttat gagaacgtgg aagataatga agtattgccg ctattttatt ctaatccaga
    42241 aaagtatact tttttattac agattttctt tttgaacaaa cgctttttgg caatcaaaga
    42301 tgctttcagc catgatgaca acgtactaga ccgctccatc tacgaagata gtatgctgtt
    42361 tcatttgaat gcagatttag ggcgtgtttc tgaagtagaa gtaaagcagt atgaaggtct
    42421 tttagaaacg atgctgaagg agttagaaga aatttcgcca caaaagaaac cagatctact
    42481 ggtttatatt cgtgtatcct ttgaaactat gttagcgaga atcaaaaaaa gaggccggga
    42541 atatgaacag ctagaacaag atcctgaact ctattcctac tataaagaac tcaatcgacg
    42601 atacgaagag tggtatgaac agtttgatat atgtcccaaa atagtgatcg atggggacaa
    42661 atatgatttc gtagccgatc cggcatgtgg agaacaaatc gtacaagaaa tcaagatgcg
    42721 ggcaaagaaa atgacagaag aggcagatgc ccagtcgatc cgctacacta caaataaccc
    42781 gaaagcaaag ggaatcttta caactaaata atataaaaac taagcaaatt gctcactcgc
    42841 agatatttct ctgtgagcag catcttgctt agtttttttg attcattgag atcaaatagt
    42901 gaaccgattc gtatgataaa attgccataa atgaaatgtc tgagtgaggg ccatgatcaa
    42961 aaataaaatg gaaacgatca aaatcgaatg ggcgccaaac agatgatgac agaaaacaag
    43021 gacaatagct cctgcgataa aggcaagaac gacacttaga tagtggaaaa atcgatcaaa
    43081 atctgctttt tctttagaaa tacaataatc atataagttc gttgctaccc cttttaaatt
    43141 tccagttgta aataaattag tgtaggcacg cccgttgatt ttatcaaaag ctacccactg
    43201 gatcgatgca gtaaaagcaa tcaaaatcgt tactaatgcg ggatgctcat ggacgggtgt
    43261 caaactaaca aagaaaaaaa tcactgcttc ataatataga acaaacaagc gccagaaatg
    43321 tttttctttt tttctaaaat aatcaattag atactttgtt agaagaatcc ctaagaaaaa
    43381 gaaaagggta gacaatactt ttttaccaac acttagccat tctccgtcaa atgcttggat
    43441 gatcgataga atgatattgc cagtttgagc agaggcaaaa gcaccatatt ggatataagt
    43501 ataactgtcc atggctcctc cgataaatgt cagcaaaagt cctattgtac gcccctcgtg
    43561 aaaggaagtc tgcatttttt tcatcacctt ttatgaatat ttttgtcttc cttatcttag
    43621 cataaacgat tgaaaaaaag gaaaaatttt cagaaaacta aaatcatatc gcttcccatt
    43681 ttcattttta gaaaggtctg ttagtataaa gaaaaaatag acaacgaaac tttaaataac
    43741 caacttgaaa taaacaaatt caaagaagaa agatgggaag gaaatcaatc agttgaatga
    43801 aaaagaaatt ctccgattac aaaaagaatt gaaacgctgg gagaacaagt ataaaaagct
    43861 tcaacaagtc tttcggctac aagaagaaat cattgctacc tatgaagcgg cttatggcga
    43921 agcacccgga cttattgagg aagaagtaca agtaaaagaa agtgaaggaa acagctcttt
    43981 ctttaaaatg atggagaaac gttcctataa tcgcttcaat caagaacaaa aagcagctat
    44041 cacatatgat atgaagaaac atcttcgaat catagcagga gctgggagcg gcaaaacgca
    44101 aacaatctgt gcaaaagctg tttatctgat gacgcaaaaa caagtagacg aagaacgcat
    44161 actaatgatc acttttacaa ggaacgctgc aaatgaacta aaaaaacgag tagataattt
    44221 cagccagaga aaaaccgctg tccatatcgg aacattccat agtatctttt ttaggatata
    44281 caatgaaatt tgtcgaaaat ttcctgaagt agcaatgcaa ggaatacaag gagacttttc
    44341 aaaggatact gcacaaaaag tgaatgctgt tttgcaacag ctgatacgta aatataatct
    44401 ttatatattt gatcaatatg gagaaaaaac gattgcttct cggttagact attggcagaa
    44461 tatgaacctt tcagtagaag aaatggttca gttagttaaa gaaaaatatg attccattga
    44521 taagaatgca cgacagccga tatcagaacg actgtatgga ttgctcacgg aactccaaga
    44581 acaaaaaaga agccagcaat tgctagagtt caatgatgta ctccaaaatc tgaaaagcgc
    44641 tttggagaat gaggagatcc agcattatat cggccaaaaa tatgattatc tattcattga
    44701 tgaatttcaa gatactaatc cacttcaatg ggaaatcgtg aaacggatga caaaggaaaa
    44761 caggatcaag ttgattgttg ttggagatga tgatcagagt atctatggat tcagaggatc
    44821 agagccagca tacatcaaga actttgaaaa agaatatcct accaaaactc ttttcttatt
    44881 aactaattat cgttctcggg cagctattgt ccaaggagca aatagattga tcagctataa
    44941 taaaaatgat cggataccaa aggcgatgat tccagcacaa aaagaagcag gtgttatgga
    45001 agcctatttg ttttctgata ctaaagcaga aagtcagtgg ctaatcaaac aaattcagac
    45061 atttattcaa aaaaatggga aatataagga atcaatcata ttataccgat cagcttcaca
    45121 aacgcagcag cttgtccaat ctctgctgaa aacgaatatt ccttttgtac tggaagcaga
    45181 tagtccatat gaaggtatct ttggtatcaa gtctttccaa catttctatc aaaaaattgt
    45241 tcattggcaa acagcactga atctgcaaaa gaaaaatcag gcctaccagc aattgctccg
    45301 gcagctgatg gcagactgct acctgaaaaa aagtgaatgc gatcaatact tttctcctaa
    45361 atatcaaaat atatccgttg cagattatat tttgtcgata agccccaatt taaaatcgaa
    45421 atctgcagaa atccgagagt ttgaggaagc gttgcgtaaa acagaccagc atcaagaaat
    45481 ctattcgctt gttcaaagct atcttcatct gccacgtata gctaaggaaa tcgaccagag
    45541 tgatcaagaa tggatacgag aagaagtaaa gcagcatgct actttcagaa gactccaagc
    45601 cttatcgcaa gaaacccaag cgacagctaa agaattaaaa acccgcttga ttgcttacag
    45661 acaaggaaaa cttgatgcac tatgtatcca gagcattcac aaaagtaaag gtcttagtta
    45721 ccgaaatgtc tttttgattg gttgtaacga aggaagtttg ccttataacg gagcgacaga
    45781 aaagaaagta atcgacttta atgaaataaa agcagaacca gtaacgacga tagaagaaga
    45841 acgaagacta ttttatgttg cgatgactag agcaagaaat cgtctgtatc tatgtgtacc
    45901 tcaaatgaaa aattcaagaa aattgaaagt atcgagattt atcaaagaaa ccgggagtcg
    45961 tgtgaaaaaa ggaaagtgat agaagagagg gtgtgacaga agtggtcagt ttcaagaaag
    46021 aagaaggaat gtacgaaaat tgcttctcaa atttttgtga aatttcagct tattttcgaa
    46081 gaagctattt ctggaacaca gtttattcgg aaaagggagg tgtgacaaga attttgtcac
    46141 acctccctta tttattttga aaatgagaat actattatca aaatagagaa tatatagaaa
    46201 aattctcatt attcaaacgt aaataatcag ttattttgat tttttttata ttttattagc
    46261 taataattgg tattttaaaa gaaattactg tagaattgga ttataattaa aaaggagtga
    46321 gaaaatgata aaagtatata cttcgcctag ctgtacttcc tgtagaaaag caaaagcatg
    46381 gttgcaagcg aatcaacttg aatttgaaga gaagaatatt tttgccgaac cgttaacaga
    46441 aagtgagatc aaaaagatct tggcagcgac tgaaggagga gttcaagata ttatttccac
    46501 tcggtcgaaa atttacgaaa agctgggcat agattttaac gaattaactt taaagcaaat
    46561 gatcgtctta ttcaaagaat atccttcatt attgagacga cctattttga ttgatgaaaa
    46621 aagaatacta atcggattta atgaagatga gatccggtca tttgtccctc gtgaaattcg
    46681 atgtgttgcc agaaatctga tctatttaca aaacaataac atcttaaatt catagggagg
    46741 gagccttcgt ggaagtgaaa gtctatggat cagcgcactg tgtaacaagt ctgaaggcga
    46801 aacaatggtt agaacaccat caattgcctt atcaatttgt tgacttagaa gaacgcgatc
    46861 taagtacaga agaagcagaa gaattatgca gttttgaaga agtgcaagca gaacagctat
    46921 ttgcgacttg gtctgaggct tttcacaaca ttgcgattga cctttcctgt gtaggaaaaa
    46981 aacaactgat ttttttatgc acacaacata ccaatctcct cagacgtcct ttgattatta
    47041 tcgatgaagt tctatttatt ggatacaatg agcagttgat ggaacagctt atcttaaata
    47101 aatagacttt aactgtttta atcaagtcac tgagcatttc atacagttgt aacagtcgaa
    47161 cacttagcat caagcgtgtt atgtgttctt tttttgactt tatttttcta ctatagagac
    47221 atgctcaatt tatgtggtca aaattcaaat ctaggtgggg atatagagtt aaaaatatat
    47281 tgacatgtgt aaatttacat gatatattca tttctgttgt tttaagtagc aaagcaataa
    47341 aatagtattt taaaaaacat ataaaatagt tgttgacatg ttagaaatga catgataaga
    47401 taactgagtt gttaaaaaag aaccacttgt gaagcttgat tctatcgaaa aaaacttcaa
    47461 aaaagttctt gacaaataac aaatgataag ttatgataaa tgagttgctg taagatttcg
    47521 aaaaacgaaa tcaaaaaaac ttttaaaaaa gagttgacaa ttacttgtct ctctgatatg
    47581 atataaaagt tgctacggca gccaaaaacg aatcggggaa cactcctgat gaagtagacc
    47641 tttgaaaact gaacaaagta agacaaacca aatgtgtagg gcgtcttgat tcaattcaag
    47701 acaacaaaca
//
LOCUS       DAPBBV010000023        47470 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.023, whole genome shotgun sequence.
ACCESSION   DAPBBV010000023 DAPBBV010000000
VERSION     DAPBBV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.023"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(53..787)
                     /locus_tag="RD486_001530"
     CDS             complement(53..787)
                     /locus_tag="RD486_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDT7663265.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="RD486_001531"
     CDS             1114..1524
                     /locus_tag="RD486_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDT7663266.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="RD486_001532"
     CDS             1517..2218
                     /locus_tag="RD486_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDT7663267.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="RD486_001533"
     CDS             2218..3804
                     /locus_tag="RD486_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663268.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="RD486_001534"
     CDS             3823..4044
                     /locus_tag="RD486_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HDT7663269.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="RD486_001535"
     CDS             4041..4802
                     /locus_tag="RD486_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HDT7663270.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="RD486_001536"
     CDS             5182..5691
                     /locus_tag="RD486_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDT7663271.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="RD486_001537"
     CDS             complement(5766..6305)
                     /locus_tag="RD486_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDT7663272.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="RD486_001538"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="RD486_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDT7663273.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="RD486_001539"
     CDS             7318..8169
                     /locus_tag="RD486_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDT7663274.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="RD486_001540"
     CDS             8197..8832
                     /locus_tag="RD486_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDT7663275.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="RD486_001541"
     CDS             8852..9625
                     /locus_tag="RD486_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7663276.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="RD486_001542"
     CDS             10033..10830
                     /locus_tag="RD486_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HDT7663277.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="RD486_001543"
     CDS             10808..11221
                     /locus_tag="RD486_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7663278.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="RD486_001544"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="RD486_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDT7663279.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="RD486_001545"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="RD486_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDT7663280.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="RD486_001546"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="RD486_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDT7663281.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="RD486_001547"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="RD486_001547"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HDT7663282.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="RD486_001548"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="RD486_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HDT7663283.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="RD486_001549"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="RD486_001549"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDT7663284.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="RD486_001550"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="RD486_001550"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDT7663285.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="RD486_001551"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="RD486_001551"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDT7663286.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="RD486_001552"
     CDS             21905..22483
                     /locus_tag="RD486_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7663287.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="RD486_001553"
     CDS             22535..23017
                     /locus_tag="RD486_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HDT7663288.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="RD486_001554"
     CDS             23134..23508
                     /locus_tag="RD486_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663289.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24186..25538)
                     /gene="brnQ"
                     /locus_tag="RD486_001555"
     CDS             complement(24186..25538)
                     /gene="brnQ"
                     /locus_tag="RD486_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDT7663290.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25685..26275
                     /locus_tag="RD486_001556"
     CDS             25685..26275
                     /locus_tag="RD486_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDT7663291.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26403..27752)
                     /locus_tag="RD486_001557"
     CDS             complement(26403..27752)
                     /locus_tag="RD486_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7663292.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27920..28660)
                     /locus_tag="RD486_001558"
     CDS             complement(27920..28660)
                     /locus_tag="RD486_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7663293.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28673..30265)
                     /locus_tag="RD486_001559"
     CDS             complement(28673..30265)
                     /locus_tag="RD486_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7663294.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            complement(30833..31129)
                     /locus_tag="RD486_001560"
     CDS             complement(30833..31129)
                     /locus_tag="RD486_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663295.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31305..32030
                     /locus_tag="RD486_001561"
     CDS             31305..32030
                     /locus_tag="RD486_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDT7663296.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32023..32865
                     /locus_tag="RD486_001562"
     CDS             32023..32865
                     /locus_tag="RD486_001562"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HDT7663297.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32868..33389
                     /locus_tag="RD486_001563"
     CDS             32868..33389
                     /locus_tag="RD486_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDT7663298.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33642..34205)
                     /locus_tag="RD486_001564"
     CDS             complement(33642..34205)
                     /locus_tag="RD486_001564"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDT7663299.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVIYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34456..34725
                     /gene="rpsO"
                     /locus_tag="RD486_001565"
     CDS             34456..34725
                     /gene="rpsO"
                     /locus_tag="RD486_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDT7663300.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34913..37039
                     /gene="pnp"
                     /locus_tag="RD486_001566"
     CDS             34913..37039
                     /gene="pnp"
                     /locus_tag="RD486_001566"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDT7663301.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37549..37815
                     /locus_tag="RD486_001567"
     CDS             37549..37815
                     /locus_tag="RD486_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7663302.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37992..39950
                     /locus_tag="RD486_001568"
     CDS             37992..39950
                     /locus_tag="RD486_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HDT7663303.1"
                     /translation="MTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40304..41605
                     /locus_tag="RD486_001569"
     CDS             40304..41605
                     /locus_tag="RD486_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDT7663304.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41735..43105)
                     /locus_tag="RD486_001570"
     CDS             complement(41735..43105)
                     /locus_tag="RD486_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDT7663305.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVNPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43287..43610)
                     /locus_tag="RD486_001571"
     CDS             complement(43287..43610)
                     /locus_tag="RD486_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HDT7663306.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43935..44543)
                     /locus_tag="RD486_001572"
     CDS             complement(43935..44543)
                     /locus_tag="RD486_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HDT7663307.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44873..45589
                     /locus_tag="RD486_001573"
     CDS             44873..45589
                     /locus_tag="RD486_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HDT7663308.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45602..46297
                     /locus_tag="RD486_001574"
     CDS             45602..46297
                     /locus_tag="RD486_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDT7663309.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46381..47010
                     /gene="udk"
                     /locus_tag="RD486_001575"
     CDS             46381..47010
                     /gene="udk"
                     /locus_tag="RD486_001575"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDT7663310.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15391 a         8787 c         9878 g        13414 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcacagcatg acagcattgg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ctagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttttt ttgcgaaaac tatttttata tcatatatat gtctaaaatc tatattataa
    23881 aagaaatgtt gtttgatcag cttctcttcg gtattagttc aaaacaaaac ggcaaagtat
    23941 atggagctac tttgccgttt tgtttctcta atactcaggt cagtttatag acgctcaata
    24001 aacggtgttc aaaagccagt ttctcggtat taagtcaaat ttatgcaaaa atgtgagaag
    24061 ccattttcaa aaaatatttc ttaatactcg aaactgagcg gctttttcac gacctctcaa
    24121 taaacagtgt tcaagagaca gcctatcggc aataaggctg aacgtctctt tcacaacctc
    24181 ttttatcaat ctgctacttc ttctttctta gcgaaactcc aaatcagtcc gataacaaaa
    24241 ccgataactg ctggtacgat ccaccccatc cccaatttga aaaacggcaa gtagctttcc
    24301 gcaacatata aaagattttg aacaataggt gtttgtttga tagtttctgg gcaagcgttc
    24361 aacccatcaa aaatcgaagc aatcaatgta aaataagtag tcattcgata aacagccgta
    24421 cgctgcttaa acaaaggacc aactaacact agtaaaatca gtgtcattgc taatggatag
    24481 atgaacatca aaacaggcaa cgaaaattga atgatattcg tcaagcctac gtttgccgct
    24541 aaacaaggaa ggatactagc aagtgcaaca aagaatgcgt aatttctttg cggaaacaaa
    24601 tctgtgaatg tttctgcaaa agctgtaatc aaaccaatac cggtcttcaa gcaagctaat
    24661 ataacgataa atgctaataa gatactgcca taagtaccta aataatgatc agcaatctga
    24721 gccagcgtga tcccgccatt ttcacttaga gcaaagctac ctaagctcat agcacctaaa
    24781 taagcgagca aagtataaat gattcccatc aatataatgc tgatcgcacc agatttgatc
    24841 gtgtctttag cgatttcagc aggttttgtt acacccatgt tttggattgt tgtgacaatg
    24901 atgatcccaa atgctaaagc agcaagcgca tctaatgtgt tatatccttg agtaaaccct
    24961 gtgaaaaaag catgctcttg ataatttggc tgaataggcg cttgatttac agaacctagt
    25021 ggattcaaaa aagcaaggag aagcaaagca cctaataaaa ccaaaaatgc aggattcagg
    25081 aactttccaa cataatctaa tatctttgtc ggttttcttg aaaaccacca agccagcaca
    25141 aaaaatacaa tactgaaaat tgctagatat agcgtctgtc tgctaggatc gataaatggt
    25201 gctaaaccaa tctcgaaaga tgtggttgca aggcgaggta aagcaaaaaa cggtccgata
    25261 actaagtaaa gcaagatggt aaaaaccatc gcatatgttt gatttatccg ttttgctaat
    25321 tcatatacac ctgagctttt cgatacacca atggcaatca cccctaagaa gggaagaccg
    25381 ataccggtaa ccaagaaacc tagattcgcc caaaaggtag cagcgcctgc ttcttgaccc
    25441 aaatgaacgg gaaagataag atttccagca ccaaaaaata gaccgaaaag catggagcct
    25501 ataaaaagat agtctttaaa tgataatttt tttgtcatac ataactcctt tacggttttt
    25561 ttaaaagtaa caaaatttcg aaaaatatgc aacaattttc agaaaatttc ctatataaaa
    25621 cgacggttat ttaataacgt aagtgataaa ataaaagcgc tgaatcatct gaggaggaat
    25681 catcgtgaca aagtcgagat tagaagcatt tactgatgga gtggtagcca ttgttttgag
    25741 agttcttgta ttagagatca agatccctaa tacatctagc tttcattctt tatgggtcat
    25801 ccgaaataca ttattagctt ataccatcag ctttatattt gttgcggtga tctgggtgaa
    25861 ccatcatcgt atatttcaga tggcagaacg aattaattac cgagtggtct ggtcgaatat
    25921 ctttttgctc ttttggctga ctttatgtcc ttctgttact agttgggtcg ggcgtaaccc
    25981 tgaagctttt tggcctgaga tggcttatgt cttagtatac acgatgtgga gtttttcttt
    26041 tggtatcttg atgaggcaaa tcatgaaagc aaataaacca gattcccatg tcgtgagagt
    26101 tttgtcaaag gaccgtcgaa gtcttatctc catgatgatt aacttatgct tgattgccgg
    26161 tgtctttttt gtaccgttga tcgggttatt cggacgtttt tttgtatctg gtatttggat
    26221 tttttcctat aaaaaagcag atgcctatta tcagcggttg tttccgggga aatagaaaag
    26281 aggctgggac agaagctttt aactccaaga aataagccga aatttcacaa aaatttaaga
    26341 agcaattttc gtaaattcct tcttatttct cgaagctgac cacttctgtc acaactactt
    26401 tcttacttct tacgttcata tttcatatga tagattagta atagaagcaa gaaccacaca
    26461 ggtgttagta ataaagcgat tctcgtatct tttcctagga acaagacgac acacacaaag
    26521 gccatgtaaa gaaataccag ataattacta aatgggtaca acggcatttt aaatgaatga
    26581 gcttttttgc cgaggatact tttacgatat ttcatgtgcg tgtagacaag catactccag
    26641 ataaacaaga aacaagtagt ggcaatactg cttactagtg tgaatacttc actaggcatc
    26701 acgtaattca agataacaga aatgaaaatg acgatagtag aaaatgtcaa agcattccct
    26761 ggcacatgat gtgttgttaa ctttttgaat tttttagggg cactgccttc ttgcgctaaa
    26821 gaacgaagca tacgtcctgt actatatatt gcactgttgc aggcagaagc tgctgcactt
    26881 aatacgacta aattgatcaa ggaagcagca atcgtgatcc caatttccga aaatacttct
    26941 acaaatggac tgttatctgg attcaagctg ttccatggat agattgccat aatgacaaaa
    27001 agagatccta agtaaaataa gatgatcctg ataggaatat tattgatagc ttccggcaac
    27061 actttttcag gattttctgt ttctccagcg actaatccaa ctaattctat cccagcaaaa
    27121 gcaaaggtta ccatttggaa agctaagata aatccttttg caccagttgg aaagaatccg
    27181 ccatgagacc atagattcgt gatactggct gtgccaatat ctgtcgtata gtgggtgagg
    27241 atcatataag ctcctacgag gataaaggca atgatcgcta caactttgat caatgcaaac
    27301 caaaactcta actcaccaaa caatgagaca gccaccatat tcaagcaaag aagaagacct
    27361 aatgcaatca gttcaggaag ccactgagga acaccaggcg cccagtagcg tacatacatt
    27421 ccgatggctg ttaaatcggc cattgcaatc gatacccagc agaaccaata cgtccagcca
    27481 gtgatgaaag ccgctttttt gccaagatat tctgcaacaa aatccagaaa agaatggtta
    27541 ttggtgtttg ataacagaag ttcgcctaac gcacgcataa tgaaaaaaca gatgcatcca
    27601 gtaataagat aggcgagcaa tatcgaaggg ccagctagct ggatagactt tccggaacct
    27661 aaaaacaacc ccgttccaat cgctccgcca atagaaatca gttggacatg tctatttttc
    27721 agtccacgct gcagttcttg ctcttcattc atttttaaat catcctaact aaaaaagttt
    27781 aattacttcc atattaaaag agttttctga aaaacacaac taagattcca aaattttcag
    27841 aaatttacct tttatgagta attcataaaa aagaactgcg gtaaacaccg cagctctttg
    27901 tcccaatcag ctattgatcc taagcattta aaatacgtga aaggaattct tttgtacgtt
    27961 cttctttcgg atggacaaag atatcttctg gtgtaccttc ttctgcaatc acacctttat
    28021 ccataaaaat gacacggtca gatacatctt ttgcaaattc catctcatgc gtcacgataa
    28081 gcattgtcaa gccagtatgt gctaagtctt tgatcgtatt aagcacttcg ccaaccattt
    28141 cagggtctaa cgccgaagta ggttcgtcga atagcaatac atctggattc attgataatg
    28201 cccgagcaat tgcgacacgc tgtttctgtc caccagataa ttgtgctggt ttggcttcga
    28261 tataacgatc cataccaact ttttccagat tttcgattgc tacttttttg gcagtttctt
    28321 tatctcgttt caggacagtt gtttgaccag acatacagtt ttccaagaca ttcatattgt
    28381 tgaacaggtt gaaggattgg aaaaccatac ctagattcgt tcgatattta ggtaaattat
    28441 atttaggagc taatacattt tctccattat aaatgatctc gccgcctgtt ggtttttcca
    28501 gtaaattgat acagcgcaag aaagtagatt taccagaacc ggaagaaccg atgatcgtca
    28561 caacttcacc tttattgact gttacgctga tatctttcaa tacttcattt tcaccgaagc
    28621 tttttcttag atgtttgatt tcaataattt tttcattcat gattcttcct ccttattcct
    28681 gcaaatttga attgtcgatt tcttcaagct tggtataagc tgaaggacca tcgattttct
    28741 tttctaccgc ccgcaggatt ctggtgatcg taaaggtcat gactaagtag atgatcccga
    28801 cgatcgtaaa tgtttggaag aattggaaat tcgcaccgga agcagagttt ccttggaaga
    28861 acaaatcagc tacgccgatt acacttaaaa ctgctgtatc tttgatattg ataacaaact
    28921 catttcctgt tgctggcaag atattccgta aaacttgtgg aataacaact tttctcatcg
    28981 tttggccatg ggtcatacca atggcttgcg cagcttcgaa ctgcccttca tctactgcaa
    29041 aaatcccccc acgaacgatc tctgtcatgt aagctccagt attgagagag acaataaaca
    29101 aagcggcaat cgttcggttc aatgaaatgc caaaagcgag tgccagaccg tagaagatga
    29161 ccattgcttg taccatcatc ggtgttccgc ggaatacttc gacatagata gaaagaagtg
    29221 catttccgat tttttggaag aagcgagtca gtgcatttcc tgattcaggt accgaacgga
    29281 agacaccaat cagtaatcca agtgtagtac cgacaactgt cccgatcaat gcgatgaaca
    29341 aggtaagtcc agcacctcgt aagaacatat tgccgtattg tttccaaatc gtagtgaaat
    29401 cagaaatgat gccaggtttt tcttcactat cagttgcagc aggctgatct ttgactgctt
    29461 ggtccataat tttggttcgt tcatcgttag agatgccaga aagaatctgg tttacttttt
    29521 ggatatccgg gtcgccttta cgcataccaa cagaaatctg aacatcttcc gggtttgtct
    29581 ggaagccatc tgcaccgctg aattcaagca tttccaagtc tttgttcaca ctagttgccg
    29641 ttacaccttc cggacgttcg ctgacataac catcgatcat tccagaagct aaagctgttc
    29701 tcattgctga gaaattatcc attgcttgtt gtttctgcac atctggtatc tgatcgatca
    29761 cagtatagtg gaatgtattt aactgagcag taatctttgc tccagaaaga tctgctaaac
    29821 tttttgcttt tgcatatttg ctatcttttt gaactactac tactaattgt gattcgtaat
    29881 aaggatcggt aaaatcaatt tcttttcgtc gttcagcagt agggctcatt ccggcgatga
    29941 tcgcgtcgat cttgcctgat tgaagggcag gagccagacc atcccatttc gtttggacga
    30001 tgactaattt tttccctaaa ccatctgcta cttttttagc gatttgaaca tcataaccgc
    30061 cggcgtaact attttggcct tgaattggca aggcattatt ctcatctgtt tgttgagacc
    30121 agttgaaggg tgcataccca gcctccatac ctacgcgaaa ctcatcgctc ggtgtttttt
    30181 catctgcatt tgccagagat cccacactga atagtgagaa gacaaaagca aatagtacgg
    30241 caactgaaac catatttttt ttcatttttt tctccctttc tgattatatg atacacgagc
    30301 ggtctagatg aaatgcggta aagctttatc tgaaaaaata aaaagcgacc gatttataga
    30361 tataaaaagg ccgctaaaat tccataaggt gataaacctc tcacaaaaca tagcgcaact
    30421 tagcatcact gctaagacag tccgcaagct cttaacttgc gtcccaacat acactccaag
    30481 caaaaaagtg cacatttcgg cgatcctccc tattcctgct tctccatgtt tgcttcactc
    30541 cacagggtta atgattctcg cgacctctac ctcattgatt gaggcatctc gtattcagtt
    30601 atttatacaa aaaaagttta cgatactcga gaggctttgt caatctataa ctgctgtttt
    30661 ttgaaaaaat actgataaat atagaaatct ttacttttac cgaaaaaaca atcaaaatgt
    30721 gaatcatcta tccattgcaa acgatagtat aattatacac aaaaatgtat gtaatacaat
    30781 aaaaaaagaa ctagaacaga aaatttcctg tgtccagttc catctcgatc atttaagctg
    30841 ccgctttctt tggctcacgt cctaggatcg cttgcaaaag aacaacgacg ccataaatgg
    30901 ctaatattag ataaatcaaa cttgagtatt gggtgattcc ccagccccat gttcgatata
    30961 cggctaatgt aatggctaaa acaattgcgg caatcacgtt gaataaagca aaagcccaaa
    31021 gatttccatt ttctttgcgt acaagataaa aaacagagaa ataaacgctt aacgctaacc
    31081 aggcgataca agccagaata acgccccaat aaataaagaa tggtaacata tcgattcacc
    31141 tcacttttat acagcagtat tgtaacacgt tttcattctt ttgtcagtga acattgtgat
    31201 aaattgttca aatgcccata acactttttt attcccattt ttctgacttt tcaacaataa
    31261 atttgttcga gtatgggcta taatggaaag tgaggtgaca aaacatgaaa caattaacag
    31321 tagacgaagc agcaaaagag atattagctt atcagcaaat tacatttttg accggtgcag
    31381 gggtatccac accttctgga gtgccagact atcgatcttt gtcaggaatc taccacggga
    31441 tggagcagcc ggaatacttg ctgagtcatc aagcaatggt gaatgaaccg gataaattct
    31501 atcaatttgt caaaaagatt tatcatcctg aagcaaaacc caatatcatt catttggaaa
    31561 tggcacatct agcgaaagaa aaaaatgttt gggttgtttc ccaaaacatc gacggtttgc
    31621 acgcaaaggc taaaagcccg caactcgtca attttcatgg aagtttgtat caatgtcatt
    31681 gtcgaaaatg tcaacaaacg gtagactgga aagaatatct tcacagcgac aaacatcaag
    31741 catgcggagg acaaatacgc ccagacatcg tgttatatgg tgaagggttt caagatggag
    31801 tcatggagca ggcggcttat gccgtcagcc aagcagagct gatcgtcatt gttggaacga
    31861 gttttcaagt tcatccgttt tgtgatctgg tacagtttcg ccagccgtca gccaaaatct
    31921 tagtaatcaa tcaaacgcct gtttatttag cggagcctta tacgtttatt caagaagacg
    31981 gagcggttgt tttcaaaaaa atacaagaat taggagcaga ttatgactga attcaaaacc
    32041 gaaaaagaaa aaatgattgc aggcgagctt tattttgcca atgatcctga gctggttgcc
    32101 gaccgtatgt ttgcaagaag tcaaagccaa atcatcaacc aagcagaatc agcggaactg
    32161 cgatcccaat tgttgaaaga gacttttggc cgtacaggga aaaaaatcta tatggagcca
    32221 gttatcaatt ttgattacgg atataatata tttgttgggg agaattttta tgcaaatttc
    32281 aattgtacat ttttagatgt cagcacgatt gaaatcggtg ataactgcat gttcgctccg
    32341 aatgtccagc tttacacggc gacgcatcca ctacatccag tgaaacgtaa cagcggtctg
    32401 gagtacgcaa aacccattaa aatcggtaat aatgtttggt taggcggagg agttatcgtc
    32461 acgccgggtg tcactctagg ggacaacgta gtagtcggcg caggttcggt tgtgaccaaa
    32521 tcttttcccg acaatgtagt gattgcagga aatcctgctc gtatcatcaa gacagtagag
    32581 gaagaactaa cagaagagtc tcttgaaaca ttacgtcata agatcgatat gatcgatcga
    32641 gagttgattg ctttattaga aaaaagaatg gatacggtaa ctaaaatagg acaagtgaaa
    32701 aaagaagaaa accaagcagt ttatgatgca aaaagagagc agcaagtatt ggataaagtt
    32761 gttagtctgc tgaaaaataa gggatataag gaaacaataa cagatacgta tgttgatttg
    32821 atgaaacact cgcgcgaata ccaaaacaaa atgaaggagg aataagtgtg atcgaaggag
    32881 agacacggcg aaaacaaatc atgcaaacct tggcaaatac agaaaaacca gtgagtgcta
    32941 gcaagtttgc gaaaactttt ggagtcagcc gtcagatcat tgtaggcgat attgctttac
    33001 tacgagctgc aggtaaaagt atcgtggcaa cagcaagagg ttatatcctc gaaacagaag
    33061 aaaccaatac tgggcacatc agtaaaatcg ctgtccagca tggaaaagat caaacagaag
    33121 aagaactgag actaatcgtt gaaaatggtg gtgaaatcat tgatgtaatt gtggaacatc
    33181 ccctttacgg tgagttagca ggaactttgc acatcaaaac gccacaagat atcgattcct
    33241 ttatgagacg ttatcaaaaa agtaatgcta ctttgttatc cgaattaaca ggcggcatcc
    33301 atctgcatac gatccgctac ccagaaaagc atatgctgaa aaacatcaaa caaaaactag
    33361 ctgaagcagg aatcctctac gaaggataac atcgtagctg ctacttttta tcctagaaac
    33421 tattctatca tctctgagat aaacacccat atggaagaaa taagaaaaaa taagaaaaga
    33481 tgcgtatcca atacacagaa ttttttggaa ttgcgatttc tagatgtcta tctaaatttc
    33541 gattagtgga gaaacataaa aaagggaagt gcagcttttg agcactcccc ttttttataa
    33601 agctttcttg tagcatagta tcgaaggaac ctgccaattc tctactcgat caccaatacg
    33661 ccttctttta gtgcaaatgg attttgatcg ttgatgtggt catagaacat cacaccgttg
    33721 atatggtcga tttcatgttg aacgacgatc gattcataat tcttcaaacg aatcttgtgt
    33781 ttttcaccat tcatatcata ataagacaca gtgattttgg catggcgaac aacatatcct
    33841 ggtacttctc gatcaacaga taaacagcct tcaccttccc ctaaacaagc atcttgaaca
    33901 gaatggctca aaattttagg attatatata acagtactta gagaaggtcc atctgcctct
    33961 gggtcaggac ttggtacgtg aacagcaatg attcttttag aaatatctaa ttgaggagca
    34021 gctaagccaa caccgcctcg taagtgtagt tcttcagctt tgattggatc ttggctgttt
    34081 tttaagaact caagcatctc ttttcctaaa gagatatctt cttcgcttaa tggaagagaa
    34141 acttcttttg caacttcgcg taaggtcgga tttccttcac gaatgatatc atccattgta
    34201 atcatggaat atgtacccct ttcttaaaag actgtgtttc aagtctattt tcgcattata
    34261 gtttaccaca aaaatggaaa agtagtagta agattgtttg aaaactacct tttcttaatg
    34321 attaactact tgattttcaa cccggtttca ggtaaagtat agctgtgtgc tctaggcaca
    34381 tgacctgcca cttggttaag cgaatcacca acgttttact cagtcgcagg ggaataatcg
    34441 aaagaggtga aagaaatggc aatttcaaaa gaacgcaaga atgaaatcat caacgaatac
    34501 gctcgccatg aaggggatac tggttctcca gaagtacaaa tcgctgtatt aactgaagaa
    34561 atcaaccact tgaatgaaca tgcacgcgtg cacaaaaaag accatcattc ataccgcggc
    34621 ctaatgaaaa aagttggtca ccgccgtaac ttgttagctt acttacgtaa aactgacgtt
    34681 caacgttacc gcgaattgat caaacgttta ggcttgcgtc gttaatttta gtcaaaaaga
    34741 gtgggattca catgaatctc acttttttta ctcgtatatc aattaagtaa aattccgtga
    34801 tcaagctaga tggactccta ctaaccaaat gaaagctgct caaaagacgg ctttcggcag
    34861 ttttcatttg tttagtagcg tcttgctttc acgagaagga aaaggagaag ttatgtcaga
    34921 aaaacaagta ttcaaaacga catggggcgg ccgtccctta caaatcgaag tcggtcagct
    34981 agcaaaacaa gcaaacggag ccgttttagt ccgttatgga gatacagtag tcttaagtgc
    35041 agctgtggcc tctaaagaag caaaagatac agactttttc ccattaacga tcaattatga
    35101 agaaaaaatg tatgcagcag ggaaaatccc tggaggtttc atcaaacgag aaggccgtcc
    35161 aagtacggaa gcaacattga ctgcccgttt gatcgaccgt ccaattcgcc cgatgtttgc
    35221 agaaggcttc cgtaatgaag tccaagtaac gaacatcgtg atgagtgtag aaacagactg
    35281 ctcgccagct atggcagcaa tgctaggttc ttctttagca ctatcaatct cagatatccc
    35341 atttgacggc ccaatcgcag gcgtagaagt tggtcgtgta aatggcgagt acgtcttgaa
    35401 tccaacagta gaacaagcag aacaaacaga tatcgaattg actgttgccg gaacgaaaca
    35461 agccatcaat atggttgaaa gcggcgcgaa agaagtttca gaagaagaca tgcttggtgc
    35521 attgctgttt ggttttgacg ctatcaaaga gttagttgct ttccaagaag aaatcgttca
    35581 agcagtaggg aaagaaaaaa tggaagtgac tttactgcaa gttgatgaag tattgaaaaa
    35641 agaaatcttt gatgcttctt acgctacaat gaaagcagca gtaatgactg aagaaaaact
    35701 tgctcgcgaa gataatatcg agcaggtgaa gatcgatatc cgcgaagctt atgctgagaa
    35761 atttgcaggt catgaagatg aagatcactt gttgaaagaa gttaaacaaa tcacagaaga
    35821 tcttgaaaaa gatgtcgtac gtgaattgat caccatcgat aagatccgtc ctgacgggcg
    35881 taaattggat gaaatccgtc cattgtcatc agaggtcagc ttattgccac gtgtacatgg
    35941 atcaggtttg ttcacacgag gacaaacaca agctttatca gcttgtacac tcgcacctct
    36001 aggagagcac caaatcattg atggtttagg ggtggaagtc agcaaacgat tcatccacca
    36061 ctacaatttc cctcaatttt ctgttggttc tacaggacgt gcaggctctc cagggcgtcg
    36121 ggaaatcgga catggcgcat taggtgaacg tgcgttagca caagtaatcc cttcagaaga
    36181 agaatttcct tatacgatcc gtttagtagc agaagtattg gaatcaaatg gttcttcttc
    36241 ccaagcaagt atctgtgctg gcacattagc attgatggat gcaggtgtac caatcaaagc
    36301 gccagtcgcc ggtattgcga tgggacttgt ttctgatggt gaaaactata cgatcctaac
    36361 tgatatccaa gggctggaag atcatcttgg cgatatggac tttaaagttg ccggtacaaa
    36421 agatggtatc actgctttac agatggatat caagattcaa ggaatcacag aacaaatcct
    36481 aactgaagca ttaactcaag caaaacaagc acgtatggaa atcttagaag aattgacttc
    36541 aacgattgct gctccacgtg aagaattaag ccaatatgca ccaaaaatcg aaatgatcca
    36601 gatcgaacct gctaaaatca aagatgttat cggtaaaggc ggcgatacga tcaacggaat
    36661 catcgatgaa actggtgtga aaatcgatat cgatcaagat ggaaaagtaa gtattgcttc
    36721 agctgatgca gaaatgatca aaaaagctat caagatcatc gaagatttga ccaaagaagt
    36781 caaagttggt gaagtttatc tagggaaagt tgtccgtatc gaaaaattcg gtgcattcgt
    36841 caacttgatc aaaggaaaag atggacttgt ccatatttcc caattagcaa acgatcgtgt
    36901 caataaagtc gaagatgttg ttaaactagg tgatgagatc cttgtgaaag taactgaaat
    36961 cgataaacaa ggacgcgtaa atctgtcaag aaaagcaatg ttgaacgaag atggttcaac
    37021 gaaaaatgaa gaaaaataat ttaattcata ggaataatgt acttgtgatc gtgaaggtga
    37081 cagggggaca ataattattc gaaaaaaggg gactgtgaca aaagccgtgt cacagtcctt
    37141 ttttttcgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc agccaagtta
    37201 aaaacattag gagctgtttt tatttggctg ttcttattac ttgatgcaga acagcttttt
    37261 tacaacctct ccaataaacg atgttcaatc agctgtccct cgatattagc tcaaaaaacg
    37321 gcaaaatatg aggaactatt tttccgtttg tttctctaat actcaggtca aaccgctgat
    37381 ttcacaacct ctgattcacg gtgttccaga agcagcttct acggaaataa gctgaacact
    37441 tttgttacaa cttctttttt tctggagttt cttggcgcat atttttggag tccttctgaa
    37501 taaagcgtaa aataaaagtg agaaatatgg ataaaggagg gaaaggagat gctgaatttt
    37561 ttatggtcgt tatttatcgg cggtatatta ggtttgatag ctggcgcaat tttaggaaag
    37621 gaagtcccgg gaggcgtatc tggaaatatc attatcggtt ttttaggtag ttggctcggc
    37681 gaatttttac taggaccact gggaccggaa ctcggcggtt tttatttgat accagcatta
    37741 ttgggtgcaa ttttttgcct tgctctttat tcatttgtgg caagacgtat cagagaacgt
    37801 ccaaagaaag aataatttta ttcaaataag ttgacacttc agtgtgttac ttggataatt
    37861 agaagcaatt taggaaagcg ggtgtcatgg ataagaatat catctatcat tcaagcttac
    37921 ctaaaggata tccatataac aagaaatgag ggaaaaacgt ggcaacaacg cacaatacca
    37981 aaaagatatc aatgactggc ctgcttgtag cgatgggagt cgtctacgga gacatcggga
    38041 caagtccgct ttacgttatg aaatcgattg ttgaagataa tggcggattg tcaggaatca
    38101 atcctgattt tgttatcgga tcagtctcat tgattttttg gacattgact ctactgacaa
    38161 caatcaaata tgtcgtgatt gcattgaatg cagataacca tggtgaaggt ggaattttct
    38221 cactctacac acttgtccga aaaggtggga aatatttgat cattcctgca atgatcggag
    38281 gagctgcctt actagcagat ggggtattga cccctgctgt gacggtaacg actgcgattg
    38341 aaggcttgcg aggaattccg cagttttttg accggttcgg taataaccag aacgtgatcg
    38401 tcattatcac tttagttatt atttttgttt tattcatggt ccaacgcttt ggtacagata
    38461 ttgtcggaaa agcattcgga ccaatcatgt tcgcttggtt tactttttta ggcgtaatgg
    38521 gattaatgaa cttcagtcaa gactggacag ttatccgtgc actgaatcct tattatgcta
    38581 tccagctgct ttttagtgca gataacaaat taggcttgtt cattcttgga aatattttcc
    38641 tggctacgac aggtgcagag gcgctttatt ccgatcttgg acatgtcggc aaacgaaata
    38701 ttcgtctgag ctggccttac gtcaaaattt gtttggttat caattatttt gggcaggctg
    38761 cgtggttgtt gaatgtttat caaaaccctg aagcacagca aatcaagaac ctgaatccat
    38821 tcttccaaat gatgcctcaa agttggatcg tgatcggcgt tgcttttgca acagtcgctg
    38881 cagtcattgc ttcgcaagca ttgattacag gttcgtttac gctagtttca gaagcaatca
    38941 agttgaaact gctgcctcgg ttaaagatca tgtatcctgg gaacagtatc gggcaaatgt
    39001 atatcccagc agtcaatctg attttatgga tcgcctgttc tctagtggtt gtcacattcc
    39061 gaacgtctca tcatatggaa gctgcttacg gtctatcgat cactgtgacg atgttgatga
    39121 caacagcact gctttacttt tatcttatcc aaaatgggca ttctcgttgg cttgcatatt
    39181 tagttacctt tttcttcggt gcgatagaag tcgttttctt tatctcaagt gttgtcaaat
    39241 tcttccgagg cggttttgta gccgttctga ttggtttgat catcttagtc gtgatgttta
    39301 tttgggaaca agggaacatt attcgcgaat cgtcaaccga ggatgtgtct ttgagagatt
    39361 atatcccgca gcttagagaa ttacgtgatg atacttcttt accaatctat cagacaaatg
    39421 tggtcttctt ggttcctgat atggctgaag ataaagttgg ccgacagttc atctattcga
    39481 ttttagataa acggcctaaa agagcacgag tctattggtt tgttcatgtg gaagtgacgg
    39541 atgagccata tacgaaagaa tatcaagtag atatgatgga cactgatttt attgtccaag
    39601 tgaatctgtt cttaggtttc agggtccaac aggaaatcaa cgtatatgtt cgccaagtca
    39661 tccatgattt gatgaaacaa ggccgtttgc caaaacagcc acaaagatac tctctgacac
    39721 cagggcgaga agttggcgat ttccaatttg tcctgattga tgaagtagtt tccaatgtga
    39781 caactctagg aaaatggcaa cgtcaaatca tgcaggcaaa actggcaatc aaaaaaatcg
    39841 ctacctcgcc agaaacatgg tttgggctag agtacagcga agtaaaacat gaaactgttc
    39901 cgcttatcat tggaaatact cggaaaacat ggttgaaaga gcggttgtga aagtagcgct
    39961 ttgacctgaa ctaatgtcga atgtcagcta cttgaacacc gtttatcaga ggtcatgaaa
    40021 aagctgtact gcaacaagca gtaagaacga gcagataaaa acagcttctc atgtttttca
    40081 tctgtttggg cttaatgccg tagatgcaag cttttgaata ccgtttttat cagaggtcat
    40141 gaaaaagctg tttagcaaca agtaacgcaa tgattttgaa gtgataagga gatgtggctg
    40201 aaaaatgccg catctccttt tttattccta aatatgaata cgcattattt tcaatctttt
    40261 tgtagaaaaa gggtacaata gaaaaagaga aaggcgggag aatatggtta tcaatttcat
    40321 tattttattt ttgatgattg caattacttc attttttgta gcaagtgaat ttgctttagt
    40381 gaaaatcaga cgatcaagat tggaacaact agaaaaggaa aatgtaaaga acgccaagct
    40441 agctcttcat gttacacacc atttagataa ctatttatca gctagtcaat taggaattac
    40501 gctaaccggt ttgatcatcg ggtgggtcgg tgaaggatct gtcgcggctt tactagaacc
    40561 agtgatcggt aaactacctt ttagttcggc tattagcagt acaatctctg tggcgctggg
    40621 atttatttta gttacgtata tcgatgtggt tattggcgaa ctgcttccta agagctatag
    40681 tatcgtcaat acggagaagg tcgtcttgtt cgtagttaaa ccacttcatt atttttataa
    40741 agtaatgttt ccttttattt gggtattgaa tcattcagct gcagggctag ggaagctatt
    40801 aggtgtgcgt ctcgtatctg aaggagaaga gacattgtct caagaagagc tgacattagt
    40861 cgcattgaat tcttatgaaa aaggagagtt gaccaaagaa gaatattatt atttggaaaa
    40921 cgtgtttgaa tttgatgata ccttggcaaa agatatacaa gtagaccgta cgtccatgca
    40981 agtattcgaa gcttcagaaa ccgtcaaaga agcgataaaa gcttcgattg aacaaggaca
    41041 tactcgctat ccggttatct tagaatcaaa agacaatgtt ttaggttatg tcaccttgcc
    41101 agatttgatc aagcaatctt ataaagatga ccagctgaca gtagaacagt tgattgaaga
    41161 gccgatcgta acaactgaaa cgatccctat aaaaaaatta ttgacgatca tgcgaaaaaa
    41221 gggtaagcat attgctatct taaaagatga atacggaggg acaagcggct tagtgacgat
    41281 tgaagatatt ttagaagaaa tcgtcgggga aatccgagat gagacagatt tggacgaagc
    41341 attgatagcg gaacagtcag atggctctta tatcatctcc ggcaaactaa cattagatga
    41401 tttccagcgt tattttcatg tagagattcc agagtttgaa gaaacgaatt ttactacact
    41461 tgcgggcttt gcttctagcc gatataaaga aataaaagca ggaacaatca ttgagattgc
    41521 atcattccgt ttcacggtat tagaatacca gcatgcacat atcgattatt tcaaagtaga
    41581 gtccacggaa agaaaaacag aataaaagaa aaaaggctgt gacatttttt gtcacagcct
    41641 ttttgttatc taaaaaacct gttttcggta aacgaagaag atattttcaa taaaagtttt
    41701 catttttagc cgcaacgatt tcttttaatc aaggctatct tgcttctgca tgttctaatg
    41761 tgaaatgttc ctcttcaccc atgtgtttca attgtttcat cgaacgcata taagagtaaa
    41821 gcaacacggc aacagaaccg atccaagcta aaggagaagc tgctgctgct cctgggtatc
    41881 cccacattcc tgtaagaacg atagctgcaa aagaacgcat aagcaattcc atcataccgg
    41941 cgatcgtagg gatcttgctt tgtccaagcc cttgaagtgt gtagcgtaaa atgaacagga
    42001 ctgctaagat ccagtaaaga gacccattga tattgaagta ggtttgtgct aattcaaata
    42061 cacgtgtttc tgatgggtta acaaacaatt gaacaaagaa atgaccgaag aaaatgacga
    42121 tagcacctgc taagagacta aatccgacac tcatcagtaa agtttgacgt accccttgca
    42181 agattcggcc atattctttc gcaccatagt tttgtgcagt gaaagttgcc attgcaatac
    42241 caaatgacat catcggctga tttgcaaatt ggtcgatacg accagcagcg gcttgagcag
    42301 ctacgacatc tgtccctaga ctatttagtg ctgcttgtaa cacgatagca ccaacagcga
    42361 tgatcgaaga ttgaaacgcc attggcaaag cagcatttag gtgtacagca aactcttctt
    42421 tttcaaattt gaaatctttt ttgcgtaact gtaacaaagg catttttttc ttgatataca
    42481 ctagacacag tacgctggaa gaaacttgtg cgattactgt agcaatagct gcaccttcca
    42541 cacccatgcc aaaatagata ataaagatca aatcaagtac gacgttgatg atgaccgcaa
    42601 tgatcagaaa gaatagtggt gtgcggctgt caccaagtgc gcgaatgaca ttagaaagca
    42661 aattgaaact gactgatgca aagatcccta ataaaataat tgaaataaat gtttgtgctt
    42721 gatcaagtat ttcaggagga gtttgcatca attgaagcat cggacgaata aacaggagac
    42781 ttaggacagt taaaatcaca gtgacgacaa gactaatgac aacactagca gcaaaacttt
    42841 tcttcagacc ccgataatct tttgcaccgt aacgttgtgc ggtaataatg gctaaaccag
    42901 ctgttaaacc ttgggcaaag ccaatgatca aaaatgtcag gcttccagtt gcaccaaccg
    42961 ctgccagcgc atttttacct agcgtctgac ccacgatgat catatcgatc atattgtaga
    43021 actgctgaaa aacatttccg atcagtaaag gaacagtgaa catcaaaatc agtttagcgg
    43081 ggcttccttt tgttaaatcg cgcatctttt aaactcctta tatctttaaa atttagttag
    43141 tagtatatag cgtttatcct gagaatacca attagaaatc aatgataatt tatgaaactc
    43201 cataaaaaga agccaagaat tgagtcaaag aatcaacaac ttggcctggt ctgtaaaata
    43261 agggacatcc acgtttatct atcaccttaa tattgtctaa tctcacttgg taaaaggatc
    43321 gtttctctcg taccgtcatc ataggcgtat acttgagcag gaaattggtt cgaataggca
    43381 aacggcaaat caatatccat ttccacattg cttcctgctt gagaaaaatg catcgtcact
    43441 tttccacgat tttcgatcaa atcaaaggtt aatatatttt ctaatggaat gactccctta
    43501 agatctaggt caataataaa ccatatactg tcaatcaatt catctggcaa acttgatacg
    43561 acaccaactg aagcgtaacg gttgcggctg ctatcaaaac tttcaaacat ctgtttaacc
    43621 tccttcgaat caacgaatgt tttattttta taattaatcc taggataaac tagaaatact
    43681 tacttcaacg agggttcatt ctaataaaga atcaggaaaa atgcaacaat aattgaatac
    43741 tttttttcaa agtataaatt tttataaagg tacgataaaa gtatgcgagg aaaagcttgg
    43801 taaattagga tttttcgttt gtaaagccat ttacaaaagt ggaagcccca tatgaaaata
    43861 aacgattaga aataaaaaag gcgtgttaaa agctgctgac ccgccgcttc taacaccacc
    43921 tgattgtttc agtattattc ttctgttgaa ccgatcactt ctggttcgcc accttcacct
    43981 gtgctttctt cttcttcact ttgagcgact acagcagcga tttgctcttc actgtcggtc
    44041 acgaatttgt aatcgtcgtt ttttggaaga tcggctactg taatagaatc acctaattcc
    44101 aagtttgtca cgtcaacttc aattcgttca ggcaatttgt ctggtgtagc agatacgact
    44161 actgtataca agttttgagc taacactcca ccagatttag cacccactga ttcgccaaca
    44221 agaacgactt ctgtttcgac ttctgtttct tccgacatgt ttacagatag aaattctgca
    44281 tgttcgaaat gattggtaaa agtgttcgtt tggatcttgt gaaccaatgt attgactttt
    44341 tgtccatcga tgtccatcgt gatgactgtg ttcgctccat gttcacgcaa caatttgctt
    44401 agtgtcaaac catcgaatga gataggggta ctttctactt tatacccata aacaacagct
    44461 ggaactttcc cttcgtgacg aagtttgttt cttaatgaac ggggacgtac ttctctttta
    44521 cttacttcta atgatactga cataaccaaa attcctcctt aaaatgtgac tgtctgcttt
    44581 ggtaacggac agattttatt taagtgaatt ctaaaggcta atctcgtgca catcatcgaa
    44641 ggcagggcgc ttaaaaaagc gcaaaaggag agatgcgcgc atctcccctt agaaagtcag
    44701 gattcaactt ttctccacca ggtcattacg ctgtgtatga gaaatccaat tcactttact
    44761 atttaaccgt aacgtgaact gttaattaag tcaaggaata actatgatga tgtatttgca
    44821 agcaagaata ttcaaggtat aattaattag tagtaataag aaaggaaaca gcatgcgttt
    44881 agataaatta atagaagaaa aattagaaac gacacgcaag gaaatgaagc ggctgtttgc
    44941 tttgaagcaa gtgatgatag atggcacagt cgaatttcga caaaatcgaa atgtagatag
    45001 tttactgcat caaatcgaag tagcaggtga acacttagaa acaaatgagt cctattatct
    45061 tctcaataaa cctgaaaaag ctgttacagc tgtatcagat ccagaaaaga cgacagtaat
    45121 cgatctgatt gcaagtgccg atcgtttcca accattatat ccagtgggaa gactagatag
    45181 agatacaaca ggactattgc tgatcacttc gaatggacaa ttgggatatg aaatgctact
    45241 tccagaaaaa aaggtttcaa agacttatca agtagttgtg aacgaaaggg tgacaccggc
    45301 agacgtaaca gcatttgaaa atggaatcgt attcgctgat gggtatcaat gtaagccggc
    45361 tgatttaaaa atactcaaag cagacaagca ccaaagtacg gttttattga cgatccaaga
    45421 aggaaaattc catcaagtca aaaagatgtt cttagcccaa ggaaagaaag tgaccgcatt
    45481 gaaacggcta agcatgggac cattggaatt agatgaacag ctaggagtag gcgagtatcg
    45541 atcgttgaca ttagcagaga tgaaaaagtt aagtatttat tttaaatagg aggtcaaaaa
    45601 gatgaaatat aaaactttat tgtttgatgt agatgataca ttgttagatt ttcaattaac
    45661 tgaagccaat gctttaagtg ctttgtttgc agaacaagga atcacattga caccagaaat
    45721 cgaaaccagc tataaggctt tgaatcatca tttatggcag gagtttgaaa aaggcagact
    45781 atcacgagaa gaaataatag gcagtcgttt tgggttactt ttccagcaat ttgggaaaac
    45841 agtagatagt gatcaaatgg aaaaacgcta ccgccactac ttgaaccaag gtcatgatct
    45901 tgttccagga agtctagaaa tcctgaaaaa ggtccatccg catgctgatc tttatattgt
    45961 gacgaacggt gtgtcgcaca cgcaacatcg gcgattaaca gatgcaggaa tgcttgatta
    46021 cttcaaggat atctttgtct cagaagctgt cggagcgcaa aagccgatga aagaattttt
    46081 tgatcatgtc ttttcccaca ttcctaattt tgataaaaag caaactgtga tcattggtga
    46141 ttctttgact tctgatatca aaggaggaaa tatggcaggg atcgatacga tttggttcaa
    46201 tagaaataaa ttaccagaaa tcgaagaaat ccagcctact tatcgaatcg attcattaga
    46261 ggaactttat tcattattgg aaattgaaaa ggattaattt tcagaaaaat atagcatttt
    46321 cgtgtttttt cgctataata gattagaatg aaaaaacgga tacgaaagag gttttagtca
    46381 atgacaaaaa gcaagccaat tatcattggt gtgacgggtg gatccggaag cggaaagaca
    46441 agtgtcagcc gtgcgatttt caacaacttc ccggaccatt ccatcatgat gcttgaacaa
    46501 gattcttatt acaaggatca gagccatttg agttttgaag aacgattgaa cacaaattac
    46561 gatcacccat ttgcctttga taatgatctg ctgattcagc atgtaggcga cttactgaac
    46621 tataaagcca ttgaaaaacc cgtgtatgac tatgtagcgc atacaagaag tcaggcaacg
    46681 atcattcagg aaccaaaaga agtgatcatt ctagaaggaa tcctgatttt agaagacgaa
    46741 cgtctgcgtg acttgatgga tatcaaagta tacgtagata cagatgatga cattcgtatc
    46801 attcgtcgta tcaaacggga tatggaagaa cggggacgca cattggactc cgtgatcgaa
    46861 caatatttga cagttgttaa accgatgtat catcaattta tcgaaccaac gaagcgctat
    46921 gcggatatca ttgttccaga aggcggagaa aaccacgttg ctattgattt gattacaaca
    46981 aaagtagcta gtttcttaaa ccataaatag tgcgcagcga aacagttgaa cggactgcga
    47041 ccgtttgaaa agcaaggatt ctgctttttg aacagtcacc agccaactgt ttttttattt
    47101 ataacaagag gttgtgaaaa cagcatcttg acctaagtat taaaaagaag aaacggaaaa
    47161 tagctgttta tattttaccg ttttttgagc taataccgaa ggtcagctga ttgagcaccg
    47221 tgaagtagag gttgtaaaaa agctgtcttt gcatcaagcg ataagagcat ccaaataaaa
    47281 cagctcctca cgtttttcgt tgggttgggc ttattatcgt agatgcaagc ttttgaacac
    47341 cgtttaacga gaggttgtaa cagaagtggt cagatgcaat aaataagaag aaacttacga
    47401 aaattatttc tcgaatttgt gtgagatttc gacttatttt tttgaagaag ctcttttgtc
    47461 gcacccccta
//
LOCUS       DAPBBV010000024        47070 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.024, whole genome shotgun sequence.
ACCESSION   DAPBBV010000024 DAPBBV010000000
VERSION     DAPBBV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.024"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..303
                     /locus_tag="RD486_001576"
     CDS             <1..303
                     /locus_tag="RD486_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7663311.1"
                     /translation="EAYPFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLL
                     TYEEGITNAMIYPYSNGKIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(443..2512)
                     /gene="pknB"
                     /locus_tag="RD486_001577"
     CDS             complement(443..2512)
                     /gene="pknB"
                     /locus_tag="RD486_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDT7663312.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(2509..3249)
                     /locus_tag="RD486_001578"
     CDS             complement(2509..3249)
                     /locus_tag="RD486_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDT7663313.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(3262..4620)
                     /gene="rsmB"
                     /locus_tag="RD486_001579"
     CDS             complement(3262..4620)
                     /gene="rsmB"
                     /locus_tag="RD486_001579"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDT7663314.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(4620..5558)
                     /locus_tag="RD486_001580"
     CDS             complement(4620..5558)
                     /locus_tag="RD486_001580"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDT7663315.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(5551..6042)
                     /gene="def"
                     /locus_tag="RD486_001581"
     CDS             complement(5551..6042)
                     /gene="def"
                     /locus_tag="RD486_001581"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDT7663316.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(6057..8465)
                     /gene="priA"
                     /locus_tag="RD486_001582"
     CDS             complement(6057..8465)
                     /gene="priA"
                     /locus_tag="RD486_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDT7663317.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(8718..9023)
                     /locus_tag="RD486_001583"
     CDS             complement(8718..9023)
                     /locus_tag="RD486_001583"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDT7663318.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(9028..9642)
                     /gene="gmk"
                     /locus_tag="RD486_001584"
     CDS             complement(9028..9642)
                     /gene="gmk"
                     /locus_tag="RD486_001584"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDT7663319.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(10129..10413)
                     /locus_tag="RD486_001585"
     CDS             complement(10129..10413)
                     /locus_tag="RD486_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663320.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(10431..11321)
                     /locus_tag="RD486_001586"
     CDS             complement(10431..11321)
                     /locus_tag="RD486_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDT7663321.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(11341..11559)
                     /locus_tag="RD486_001587"
     CDS             complement(11341..11559)
                     /locus_tag="RD486_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HDT7663322.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(11529..13229)
                     /locus_tag="RD486_001588"
     CDS             complement(11529..13229)
                     /locus_tag="RD486_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDT7663323.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            13495..14268
                     /locus_tag="RD486_001589"
     CDS             13495..14268
                     /locus_tag="RD486_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663324.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(14349..14918)
                     /gene="thiT"
                     /locus_tag="RD486_001590"
     CDS             complement(14349..14918)
                     /gene="thiT"
                     /locus_tag="RD486_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HDT7663325.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(14984..15086)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15092..16063)
                     /locus_tag="RD486_001591"
     CDS             complement(15092..16063)
                     /locus_tag="RD486_001591"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDT7663326.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(16157..17530)
                     /gene="glmU"
                     /locus_tag="RD486_001592"
     CDS             complement(16157..17530)
                     /gene="glmU"
                     /locus_tag="RD486_001592"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDT7663327.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEAFFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(18033..18851)
                     /gene="purR"
                     /locus_tag="RD486_001593"
     CDS             complement(18033..18851)
                     /gene="purR"
                     /locus_tag="RD486_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDT7663328.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(19018..19842)
                     /locus_tag="RD486_001594"
     CDS             complement(19018..19842)
                     /locus_tag="RD486_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7663329.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(19815..20495)
                     /locus_tag="RD486_001595"
     CDS             complement(19815..20495)
                     /locus_tag="RD486_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7663330.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(20518..21456)
                     /locus_tag="RD486_001596"
     CDS             complement(20518..21456)
                     /locus_tag="RD486_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HDT7663331.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(21701..22564)
                     /locus_tag="RD486_001597"
     CDS             complement(21701..22564)
                     /locus_tag="RD486_001597"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDT7663332.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(22706..25279)
                     /gene="mprF"
                     /locus_tag="RD486_001598"
     CDS             complement(22706..25279)
                     /gene="mprF"
                     /locus_tag="RD486_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDT7663333.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            25420..26226
                     /gene="proC"
                     /locus_tag="RD486_001599"
     CDS             25420..26226
                     /gene="proC"
                     /locus_tag="RD486_001599"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDT7663334.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(26305..27861)
                     /gene="rny"
                     /locus_tag="RD486_001600"
     CDS             complement(26305..27861)
                     /gene="rny"
                     /locus_tag="RD486_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDT7663335.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(28272..29321)
                     /gene="recA"
                     /locus_tag="RD486_001601"
     CDS             complement(28272..29321)
                     /gene="recA"
                     /locus_tag="RD486_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDT7663336.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(29430..30671)
                     /locus_tag="RD486_001602"
     CDS             complement(29430..30671)
                     /locus_tag="RD486_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDT7663337.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(30911..31489)
                     /gene="pgsA"
                     /locus_tag="RD486_001603"
     CDS             complement(30911..31489)
                     /gene="pgsA"
                     /locus_tag="RD486_001603"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDT7663338.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(31698..32621)
                     /locus_tag="RD486_001604"
     CDS             complement(31698..32621)
                     /locus_tag="RD486_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663339.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(33360..34646)
                     /locus_tag="RD486_001605"
     CDS             complement(33360..34646)
                     /locus_tag="RD486_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDT7663340.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(34639..35907)
                     /locus_tag="RD486_001606"
     CDS             complement(34639..35907)
                     /locus_tag="RD486_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDT7663341.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            36159..36620
                     /gene="mscL"
                     /locus_tag="RD486_001607"
     CDS             36159..36620
                     /gene="mscL"
                     /locus_tag="RD486_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDT7663342.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(36679..37125)
                     /locus_tag="RD486_001608"
     CDS             complement(36679..37125)
                     /locus_tag="RD486_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7663343.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(37218..37463)
                     /locus_tag="RD486_001609"
     CDS             complement(37218..37463)
                     /locus_tag="RD486_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDT7663344.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(37578..38156)
                     /locus_tag="RD486_001610"
     CDS             complement(37578..38156)
                     /locus_tag="RD486_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7663345.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(38233..38763)
                     /locus_tag="RD486_001611"
     CDS             complement(38233..38763)
                     /locus_tag="RD486_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDT7663346.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(38767..39627)
                     /gene="rlmB"
                     /locus_tag="RD486_001612"
     CDS             complement(38767..39627)
                     /gene="rlmB"
                     /locus_tag="RD486_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDT7663347.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(39620..40015)
                     /locus_tag="RD486_001613"
     CDS             complement(39620..40015)
                     /locus_tag="RD486_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDT7663348.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(40012..41424)
                     /locus_tag="RD486_001614"
     CDS             complement(40012..41424)
                     /locus_tag="RD486_001614"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDT7663349.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(41421..41957)
                     /gene="cysE"
                     /locus_tag="RD486_001615"
     CDS             complement(41421..41957)
                     /gene="cysE"
                     /locus_tag="RD486_001615"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDT7663350.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(42043..42282)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(42279..43739)
                     /locus_tag="RD486_001616"
     CDS             complement(42279..43739)
                     /locus_tag="RD486_001616"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDT7663351.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(43909..45066)
                     /locus_tag="RD486_001617"
     CDS             complement(43909..45066)
                     /locus_tag="RD486_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDT7663352.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(45100..46470)
                     /gene="radA"
                     /locus_tag="RD486_001618"
     CDS             complement(45100..46470)
                     /gene="radA"
                     /locus_tag="RD486_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDT7663353.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(46533..47060)
                     /locus_tag="RD486_001619"
     CDS             complement(46533..47060)
                     /locus_tag="RD486_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDT7663354.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT        12846 a        10297 c         8353 g        15574 t
ORIGIN      
        1 gaggcgtatc ccttttttca tgaattagtt gaagcctttc gagacaaaga ccctgactta
       61 tttttctcct tattggcaga acttcccgaa acgttagatg acagctttcg ggaaaagctt
      121 caaaaccttc tgacctatga agaaggcatc accaacgcaa tgatctatcc ttattccaat
      181 ggaaaaatag aagcgaagaa tacccacata aagacaatga aacgagtatc ctacggattt
      241 aaatcatttg agaacatgag aattagaatc tttttgatca atcaattaat caatgtaaga
      301 taacaaaaaa tctgagccag aatgtggttc attctgactc agatttgatt ttgcacaact
      361 catcagtcct tattgacaaa gagccaaaag agaatgcaac aaatcaatgt cgcattccct
      421 tctgatatat tttattcagc acttattttg aactttctga ggtgctagct gatgaacttg
      481 tggagctgga agattcttct tttgaagagt tgcttgtgct actggagcta cttgagctgc
      541 tagaactgtc tgaagagtct ttttcagaac tagaagacgc tggatctggt cctttagagt
      601 aaattacgtt cacaaccatt cctttggtaa ttgtcgttcc tgcccctggt actgtacgaa
      661 tcactttatc tttatccacc gtgtttgaat attcggaagt ctcatgcccg atatattctg
      721 caccgacact agctaaataa ctttgtgctt cgctttttgt atagccggag atatcattca
      781 atttaggctc tgttccttgg cttacgacaa aattgatgta agtttcttct gctacaactt
      841 cacccgaggc tggatcctga ctgatgatcg aacctgatgg tacagtgtcg ctatagtcat
      901 aagtagcact aatattattg atattgaatc cttgtgtaac aagccaatta cgaacagttt
      961 cgtagttttc tcctacatga ctactcaaag tcactgtttc tggtcctttg ctgactgtga
     1021 aagtaatcgt gtctgtttta ggatcgactt ctgtatcttc tgatggagat tgcgaaatga
     1081 tcattccgct ttctacctct gaactgaatt cctcttcttt ttgaatcaag tcagcagaaa
     1141 accctaattc tttcaaactt gcttcggcat cttcataact tttaccactg taatcatcta
     1201 atttgatttt tttcgtgccg ctactaatat acagagtgac ttcgcgtttt tgcttgactg
     1261 tcgttcccgc tgccgggtct gtcttcacta cattaccttc ttcgattttg tcatctgcaa
     1321 tttcttctgt ttttgttgct acttctaatt tcgcttttgc gagtgtttct ctagcagaag
     1381 cttcagaaag atcagaaaca tcaggaacaa caacttctcc tcgcccgcca gaagcaaaga
     1441 atacagctgt tccgattcct aaaacagcaa gaatagctaa taggatcagc caccattttt
     1501 tctgtccttt ctttttagga tcaggcagaa cttcttcctc ctctggtaag gtttcgtttt
     1561 ctggcttgtc ttttggcaga ggcatagatt tgaatgaatc aggcattggt gcatcttccg
     1621 taaggggtgt gataactttt gtttcattat ccatcacatg aggctgccat ttttcttcgt
     1681 ttgcacgagc tggtgataat actgtagaaa gatcatcaga catttcctcg gctgacttat
     1741 aacggtctgc aggttcttta gccgttgccc gtaaaatcac gttttccagt gcttgtggca
     1801 catttggatc aagtgctttt atagatggaa gatcatcttg aaaatgtttt aaagcaattg
     1861 ttacagcaga ttcaccatca aacggtacgc tacccgtcaa catctcataa aggatgatcc
     1921 ctaaagcata aatatctgac tgcttcgttg ccatacttcc tctggcctgc tcaggggaca
     1981 gataatgaac agatcctagc atcgtattcg tctgcgtgat cgatgtttca gataaagcga
     2041 tagcaatccc gaaatccgtg atttttacaa caccttcatt atcgatcagt acgttttggg
     2101 gtttcaaatc tcggtggatg atttgatggt tatgagctaa agaaatagca gaaaggatct
     2161 gctgcataat atttactgct gtttcataag gaacaggata atgtgtttgg atatatcgtt
     2221 tcaagtccat tcctttgacg tattccatca ccagatactg catgttgtct tcttcaccaa
     2281 catcgtaaac actaacaatg tttggatgaa cgagttctgt tgctgctaaa gcttctctct
     2341 gaaatcgtcg aatcgcagtc tggtcatttt gaaagtcaaa tcgtaagact ttaactgcta
     2401 catcacgatc caagattaaa tcgtgcgcca aaaatacatt tgccatacca ccgctaccga
     2461 tatttccagt gatttgataa cggccattta attttttgcc caactcgatc atacactgtc
     2521 ctccttatat tcgataagaa gaacggtgat attatccgct ccgcctgctt cattggcacg
     2581 atcaatcagc tcagttactt tatgagacaa tgggccttct tgattgatga tcgttcctat
     2641 ttcttcttca gacagcatgt tcgtcaagcc atctgaacat aacagcagtc gatcttttag
     2701 ttgccaaaga tgagtagaaa catctacttc gactgttcca ggcatgccga cagaacgtgt
     2761 taaaatattt ttccttggat ggttcactgc catttcttcg ctgatttctc ctgatttgac
     2821 tagttcattg actaaagaat gatcctccgt caattgcatg attttatctt cacgaatcaa
     2881 ataagctctg ctatccccaa cattggcaat cgtgaaccag tcatctgaca gagcggccgc
     2941 tacgattgtt gttcccatac cgttatattc cggctgttct tgtccacgct gataaatcag
     3001 catattttct tcttgaatcg attgaatgaa ccattgggcg attttttcat cgtcaacagc
     3061 ttcttgtttt tcccaagctt cgcctagatt cgttaccgcc atctgactgg caatgtctcc
     3121 ggcacgatga ccacccatcc cgtctgctaa tacagcaagc ttgagacctg aacggctggt
     3181 aaatacactg gcatagtctt gatttgtgtt acgtcgtctt cctacatctg attgatattc
     3241 aatctgcatt ttttcacctc attacttttt gcgcaaacaa caaatgaaaa atccatctgt
     3301 gtaaaactga tgcggataca aagtcaacat tttctcttcg attgatgatt gtagcatagg
     3361 attggtcaaa acatcaatcc tctcaaaatc agggtgtctt tccaagaaag cagaaacaac
     3421 gtcttggttt tcttctttta agatcgtaca agtgctataa gtcagaatac cggaagactt
     3481 taaagttggt gcgcagcttt ctaaaatttc caattggatt tttggtaaat tcgctaattc
     3541 atccggctgt tttttataac gaatatctgg ttttcgccga agcagcccaa gacctgaaca
     3601 aggcgcgtct actaaaatcc gatcaaactg ctctgcttcg aactgtttac tgacttctct
     3661 agcatccatc ttttgagcgt agacagcaga agagacacct agacgtgctg cattatcttc
     3721 aatgagtttg actttgtgtt cgtgtacatc taaagcgacc acttctccac cgcatgacgg
     3781 atctaaaaaa gaagcaatat gcgtcgtctt acctccgggt gctgcacagg catctaagac
     3841 atgatgttca ggctcgattt gcatagacgg cgctacaagc atcgaacttt catcttggat
     3901 cgtcatgacg ccatcgtgga acaatgagct agaagctaaa tgcccttttt tcgctactat
     3961 accgtatgga ctgacttggc ttttttcagc tgtgatctct tcttcttgca aaacagtgat
     4021 ggcctgatct ctggaaagtc ggcgtgtatc tactcgggca ctagcatggc taggctgata
     4081 tagcgataaa ccgagctttt cagtttcttc gtatccgatt tgatccacca gtcgtttagt
     4141 catccataga ggcaggctga ttttgacaga aagtctttcg ataggatcag caatgccttg
     4201 cagatctggt gctccttgac gctgataatt cctcaagaca ccatttacaa atttccctgt
     4261 cccaggattt ccttttactt ttgcgatttc gaccgcctcg tttaaaatag catgtgcagg
     4321 gactttatct aaaaattcta attggtatac agaaagataa agaagcgtct tgacccagtc
     4381 atccactttt tttgctttag cgatcaatgg tgcaacgtaa aattccaata gtcgctgatg
     4441 gctaatcgta ccatagatca attctgtaaa taaacccaca tctttttgat ttagctcgct
     4501 ttgtttgatc atctcattca acaaaagatt cgagtaggcg ccacccttgt tcactcgctc
     4561 taatgtcagt aatgccatat atcgtactga ttttttcatt tttttaggga tttttttcat
     4621 tatttcacct gctgaccaat ctgaacttgc tgaccgcttc cgttaaggaa atcatgtacg
     4681 gcctgttttc ctttaccagc tggctgtaat tcattgatgg ctaagacggt ctgtttaccg
     4741 caagcaatcc atagattttt tttgtctttc cggatgatcg taccaggtgc tttgtctgta
     4801 gtttctgcca atacttcaac cgataataat ttccagcgta tgccctcata ggtcgtgaat
     4861 gcaattggcc aaggacgcat tccgcgtact tggttgtcaa tttcttctgc agttttatgc
     4921 caatcgattg cttcttgttc ccgtgtgatg tttggcgaaa aagttgcttc tgactcgtct
     4981 tgaggtactg gtttttgtcc atccaaaata ttgggcaatg tttctagcaa tagctttctt
     5041 cctaaaaggc taagcttttc aaacatcgtc cctacatcat cttgtttagt gattggtatg
     5101 ctttcttgcg catagattcc gcctgcatcc atttttttga tcatttccat gatcgttaca
     5161 ccagtttctt tctccccatt catgatggca taatgaacag gcgcacctcc ccgatattta
     5221 ggaagtaaag aagcatggac attgattgcc cctaattttg gtacttgcaa taacttttca
     5281 ggcaagaatt ggccaaatgc cgcagtgacg atcacatcag gcaccaattc aatgatttct
     5341 tccatttctg gcgaaccgga gattttctct ggctgcagca cacggatacc gtgcttcaga
     5401 gccgcttctt ttaccggtgt cggcgtaatt actcgtttcc gcccaactgg acggtcgggc
     5461 tgtgttacca ctgcctggat ctcgtaacct gattctatca gcccttcaag aatcggcaca
     5521 gaaaaagcag gtgtgcccat aaatactagc ttagtcatca agatgttcct ccatatattc
     5581 ttcaagttct tcttccggga tctgctgtat cattttctca atgaacaaga taccgtctaa
     5641 gtgatcgatt tcatgctgga aggcacgggc taaatagcca aaagccgtca cttctatctc
     5701 ttctccgtct cgatcataat aacgcacggt cacttcatct gctcgcttga ccgttccata
     5761 gacatgcgga atactgagac aaccttctac gtcaaggctt tcaccttttg cttcgatgat
     5821 ttctgggtta atcagttcaa atttctcgcc ttcatctact tcgatcacag caattctctt
     5881 gttttgtcct acttgaggag cagcgatccc tattccgtca ttcgcaatca ttgtctcata
     5941 taaattgtct aataaagcga ttgtctcgtc cgtgattaca tcgattggct gagcagttct
     6001 ttttaattta tcattagggt ggatcaatat aggatagcgc ataatttggc cctttcttaa
     6061 ataaagttta atggttcgtt gtcaattgcc acaaaaagac cttgtcgctg ttctttctgg
     6121 cttccattca aaatttcatc caaaacatga ggaagattcg gttcatgttt atatttgatg
     6181 attagttgat aataatatcg gtttttcact ctcaaaatca tgctgggcgt tggccctaat
     6241 agcaagcttt gagggcttaa cacttctttt agctgattgg caatctgaaa gattttcttt
     6301 gccgctactt gttcttcagg atggctggcg gttattttca cagtaaagta ataaggagga
     6361 tagcctccac gatgccgtac atgcatttcc tgctgataaa actgctcata attttgtttt
     6421 ttagccaatt ctatggcgta atgttgagga ttgaatgttt ggatcacgac ttcgcctgct
     6481 ttttccgctc gccctgctcg tcctgaaact tgggtaagca attggaatgt atgctcacta
     6541 gaacgaaaat ccggtaaatt cagggaggta tcagcattca acaccccaac taatgtcact
     6601 tctggaaagt ccaaaccttt agcaatcatt tgtgtcccta ataatatatc tgcttctttt
     6661 gcaccgaatt tttgtaaaat ctgttcgtgt gccccttttc ttcgagtggt atctacatcc
     6721 atacgcaaaa tcctagcttg cggataaagt tctcggagtt cctcttctac tttttgagta
     6781 cctgttccat agtagcggat tttattgccg ccacaattag gacagcgatt gggaataggt
     6841 tcttcatgtc cgcaataatg gcagcgcatt gaacgtgtat ccatatgcag tgtaagagag
     6901 atatcgcaat taggacatgg aagaacaaat ccacagtccc tacacatcac aaaagacgaa
     6961 tatcctcgac gattgagcag taggacagtt tgttcttttt tgtctaatcg attttgtatt
     7021 ttttcctgca aattagcaga aaaagtagag gtccgatgat tctgaaactc ttcacgcata
     7081 tctacgatct caatagctgg aagctgtgca gctgctttgg ctcggtggtt taactgcaat
     7141 aactgataaa cgcctttttg agctcgtgct cttgattcta aagagggcgt cgcgcttcct
     7201 agaactattg ggcaatgatg atatttactg cgccaaattg ctagatctct cgcatgataa
     7261 cgcggtgtct catcttgttt gtaacttgat tcatgttctt catcgataat gatcagcccg
     7321 atatttttca gcggggcaaa aatagcagat cgtgcgccta ctactacttg cgcttcttcc
     7381 cgctcaatct tgcgccattc atcatatttt tcaccttggg aaagtccgct atgtaagacc
     7441 gcaactgatt ctccgaagcg tcctttgaat cgctcgacca tttgcggagt caatgcgatt
     7501 tcaggcacta acataatagc cgttttattt tctgacaaaa catcagcgat tgcctgaaga
     7561 tatacttctg ttttcccgct gccagtgatt ccctccagca aaaagacctg atctttttgc
     7621 tgctgacctg ctgtgatgat ttgttcgaca gcattttttt gttctgcatt cagttccaat
     7681 gccgtcgttt ggtcaaatac tcggtcttta taagggtcgc gataacgttc tgattctata
     7741 aactccagcc agcccttttc ttttccttga ttcaagacag cagtactgat tcctttattt
     7801 ttgaaataag caattggttc ttcttggctc agttcagata aacacaaaag aagttctttt
     7861 tgtttcttgg cattttgccg taattttgcc cattcttctt cgatttgctt ttcagttaac
     7921 aaagaacgga ccaaacgaat cgtttttact ttatttcgtg tatggacttc atatttgata
     7981 tctactaatt gctcttggcg ccagcgaatc aattgagaaa ggctgccttc ttcttctgct
     8041 tccttccagg aaatcacttc tcgctgatca aacaatacct gaacttctgg tgtgtctgcc
     8101 aaaggataga tcaatttatc atattctgct ttcatcacac tcggaagcat cgtttgtaga
     8161 caagtgattt tgaatgcgta agtaattttt ttcatataat cagctaatga aagtaattct
     8221 tcattgacca ccggagcaag gtctagcaaa cgaataactg ccttcaaaga tggattagct
     8281 gattcttctg atttttggat agccataaca aatccttgga catgacgatt gccattacca
     8341 aaagggactt ctactcgcat cccgacttgc aaagctgttt ccatttcaga gggaaccaaa
     8401 taagtgaatg gctgatcggt ctgcatagta ggtacgtcca caatgacttc agctgttaat
     8461 gtcatggttc gtttcctcct ttttttgtct tttcttatca agcgacaaaa agttccttgc
     8521 ctattttact agagatcgat ggatttgtct tatcttctgc caaatcctaa caaaaaatta
     8581 acagcagata agaaaaaaaa gaactgtgtc aaaaagttca gacacagcct tttctaccag
     8641 acaataagtg gcgaatgttt gaaaaggaaa cagctgggtt tgcttttctt tttagatgtt
     8701 cgctctattt ttctttatta cattttttgc tcttcacgga tacgtgattc caattcgtgt
     8761 tgttcacgct ctttttgtgc ttgacgttcc tcttcttcca tcttcaaacg ttcacgtttt
     8821 aattcaggat gtggatcatt gactacattt cctgcatcga tttcttctaa agcttgaccg
     8881 acgcttttta ctgaatcaaa agaatctaga gtaggctgtg cacttgcatc caattcatgc
     8941 gcgcgtttac ttgctaaaat cactagagaa tattttgaat ttacacgatc taatagtgag
     9001 tcaattgaag gttttaacat cataagacta catctccttt aacattttaa tatatttacc
     9061 gattacgcga tctactcgaa aatgttcact ggcaataatg tttttgattc gttcaactgc
     9121 tagcggcact tcatcattta caacagcata gtcgtaaaga gccatcattt cgatttcttc
     9181 ttttgcaact ttcattcgtt cttcgattac ttcatctgca tctgttcctc ggcctacgat
     9241 ccgtgatttt aattccgcta aatctggcgg agtcaaaaag atgaatacac catcgggcac
     9301 tttttctttg acttgttttg ctccttggac ttcaatctcc aagaaaacat cttttccttc
     9361 atccaatgtc ttgttgacat atgacaaagg agttccataa taattcccga catattctgc
     9421 gtattccagc atctctccag cttcgatcat tgattcaaac tcttctttgc ttcggaagaa
     9481 ataatcaacg ccttcgacct ccccttcacg cattttacgg gtagtcattg agatcgaata
     9541 ctgaaaatca ttatcctcac tctcaaaaat tgcttttcgt actgtgcctt ttcctacacc
     9601 ggatggacca gacaacacga ttaataatcc acgctctgac atgacgacgt cctttcaact
     9661 agtctttttg tacttatcgt ttattttgca ctttttttct gcaactttca aggttatctt
     9721 taattatagc tagaaattgg taaaaaagct accctgtacc aagaggtcgt aaaaaagctg
     9781 tcctgcatca agtaataaga acagccaaac ataaacagct tctcatgttt ttcgtttggt
     9841 tggggttatt atcgcagatg caagcttttg aacgccgtgt ataagaggtc gtgaagaagc
     9901 cgattagttt cgagtatgaa gaaaaatttt gtgaaaatag tttctcacat ttttgcataa
     9961 atttggctta ataccgagaa aatggttttt gaacatcact tattcaaaat aaaaaaagat
    10021 tgtgacacga attttgtcac aacctttaaa tgtattccta gagcaaagaa gctaagcgaa
    10081 gaaatccaat tctgattatt tattgtattt ctttgttcag catccttgct aaaagcccat
    10141 attggacaaa gtattcacta cacccatgat ctcatctttt cgagaacgtg ctttttctgt
    10201 cggatcttct acctcttctg tgtcaattcg aacaataaat ttccgattca tcgtcacgta
    10261 agcaccgtcg ttgatcaaaa taaacagttc gttctcatta tagtctgcac aggcatcttt
    10321 ccatacgtca aagccgtttt tttcagaagg gatatcccgt ttaaccacag tttttccact
    10381 taattcgtgg aacgttacgt cataatattt cattatctct acctctttcg tcattcaata
    10441 ttttgtactt gttctctgat tttttctaag atcgtcttag actggacgac ttgattttta
    10501 atttcgattg catttgattt ggaaccgatc gtgttgattt cccgattcat ttcttggatc
    10561 aggaaatcta attcccgacc tacaggacat tgtgcttcga taagttcatc tagtttttgt
    10621 acatggatcg ccagacgatc cagttcctcg tgaatatctc cgcgttccaa caagatggct
    10681 agctccgtca acaaccgttg ctcatcgact ttcgctccaa gaaattcctc cagctttttt
    10741 tgatacctta tttgaaattc cttttcatag atttctacaa aactatcgag tttttttagt
    10801 acttctttga attcttcagt attctttttc aacactaaag ctaaagcttg accttctttt
    10861 tctcgactcg cctcaataga atcaagtgcg cttttcaatg tatctagagc taactgtgcc
    10921 aattcttcca tgctctcttc cggtttttct tctaccgtta cgaagttttc gtccagcgcg
    10981 aagcgttccg ccatccgact aattgacact tgattttgac taccgtatcg ttgttgaatt
    11041 ccgtctgtca attgagtgat aagtgaatca atcaattccc agttgatgac gatctgtttt
    11101 tcgtttttgc caatataagc tagattcaca aatacttcga ttcgaccgcg gcttaactgc
    11161 tgtttaataa gctgacgaaa atcgttttca acaaagttca ggattttagg acttcgtatt
    11221 tgaacatcta gaaaacgctg gttgacactt tttatttcaa tatctaactg atacgctttt
    11281 gtttcgcgga tggctttgcc aaaaccagtc atacttttca ttcgacaggg tccttcctca
    11341 ttacatattt tctattgctt tttgcagttg ttcaaactct tcgttcgtca atgtcaggcc
    11401 tttccccatt ttttcatggt ctggcgccca atctcgaaga tcgaattttg gcgggcgacc
    11461 attccagctg actaggttca gttctttacg ccaccccttg ttgttttctg acaatatagc
    11521 gatttcttct acgatttcat atgaaaattc ttgtgccatg gttgttcctc cttgagataa
    11581 tataaatata ggatcagtaa tgtgtcaact ggttgcttaa gcaattcatg ctgcaaacga
    11641 tccttgcgtt ttccttgtag cagataatca aaataaacag ttttcgtgcg ctcattttgt
    11701 attttttgct ggtattttcg ataccttcgc cattcttcag tacttaattg accaatttgt
    11761 gccaataaat catccggcat actttttata tcttgttggc agatcatttg aatcatcatg
    11821 tctacttgat agatttcatt gggcagtaaa aaatgttttt ttgctaaaag ttctagcatc
    11881 gccaatccgc atgtctctgg tacgaccctg ttcttatata aattacgcag tttttgccaa
    11941 aattttatgc ttttgaaaaa agataattct aactgaattt cttttgttaa gtaagacaaa
    12001 aatcctcgcc agtatgttct tgcaggttta acagaatgaa atgtatacca gttcccatag
    12061 taatagccta atcgtttttt catttccaga tagcctaatt gtaaatttaa ttggttcctt
    12121 tggctatcaa aaagcagaaa gctgcctagt gtccacaatg tttgacattt ccaatggata
    12181 aaaatgtctg gcatacgaat ttttttcgct gggcctggcc cttgcacatc tacgacaaat
    12241 gcctctgttg ctcctttgtt aatcgcaata tcaataggta ttttgttgcg atacccaccg
    12301 tctgcatatt tattttttcc gatctttcga taagccatag cgggataaaa tgaagcagag
    12361 gcgagtatcc aatctggtat ttcttctgtt tttgtctgtt ggatatcagt cactacttcc
    12421 gctagttctg gcagtttagt agacaccgta tataaacgta ttttgggatt atgtttgagt
    12481 aaggacaaat ccaaattgtc tttgaccatc ttttccaatg gagcagaaga aaccccgcct
    12541 tcaattagtg ctgttttcgt catttggcgt ctttctcgat agaagcgttc acgaaggtct
    12601 tcaactgcag ccatttctgg taacgcaagc acttgtcttg tcgacagctt tttccataaa
    12661 ttcacagctt ttttcatatc tccttgtaaa atcaatgcgc cgttcaacgc acctaccgag
    12721 gtacctgtga taatctcaaa gttgatatca tgttccttca gcgcctgcca cacaccaatc
    12781 tgataagcac cgtgtgctcc tcctccacct aaaacaagtg ctgtatgata gaccagcttt
    12841 ttatttaatt gtgtggttcc ttgatagccg tttttatgaa aaatacgcaa ccattcttct
    12901 gatagaggag attgaaataa aaaacaacag ttttctttaa taaaaaaacg agcgcaagct
    12961 tccatatacc gaaaaaattt tttccattca aaagtttcac cttcaatcaa cagattatta
    13021 aaaataacat ctcctctact tttagcaata gtaaaataga cggtatattt tttcgatact
    13081 gctttaaaag cacattgctt ttttgcagaa cgccaaaaag cgtctctact ttcttgatga
    13141 ctttgaaaaa atggaagggg ttgttttgct tgctggatag gcgaatacag cgacattttc
    13201 tgtgaaaagt aaactttttt tatctccatc gcgctctcct ttttcttcaa gtataccagt
    13261 acgtcataaa aaggtcatga gtctcgtatt cgactttgta gattccataa gaaaacaatt
    13321 cataaaacat cctttaaata aaaaatacaa aaatcacaaa aattaattga aaatgagagt
    13381 gttttcaatg aaaacgtgat tttgtaatgg aattttaaaa taaaagaaac aagctttttt
    13441 aatgcaaatg ttgtaaaata aaagagatta agaggaaata agaggaggaa catgatgact
    13501 gagtcagttt atgtacatat tgataccaca agtaatgctg ttttaacaaa agggctgact
    13561 gctactgact ttgcaaacag tatcgtgcat tttcctcaaa acttgctctt gcttgatcca
    13621 tctgcttctg ctggagaata tgaatcccat acagggctga aagtaatccg tggtacagaa
    13681 aatattcagc gtttcttttc ctcttctcgt aacaggcgtg gattcgatga attgaagtgg
    13741 atcgacttta ctgatttaac gatgctgaaa gaattgacac ctttagaaat ttcagaatta
    13801 ttatattttg gtcatatgaa aacacatctt cattcgccgt ttttttataa actacagaat
    13861 aattttgtat acttcgatct taatgatcag ctgaatcgga tttattatcg ctatttagat
    13921 gaattttata ggatttttgc tagtaaatta agttcgatct tgtcagataa gatcaatgta
    13981 aaaaaatctt ttttcaaaaa agaaacacct gttgaaaaaa tcagtgtgga attattgaaa
    14041 gaaatgcgta atttgatgca ggaagggatc attttttctt ttgatcaagt tggtttgatc
    14101 gatggtaaat atcgtatccc aatctatgtg attgaagatt atatttggaa attaaaaggc
    14161 acccggtatc gagaagagga aatcatcgct actttaatct actctgtcac cgatcgacac
    14221 tggcaattgg tagaagatgc cgatctttct tatctgccat tgaagtagat ctatttctta
    14281 tcaaaaaata aaaaggaaac aagaaactag gacatgattc tgtctcaagt ttcttgcttc
    14341 ttttttattt acagctcctg tcgtttatct ggcacaaaaa tcgaaggagt cgtttgttgg
    14401 atccctaata aaacgatgat cgttacaata gctgtactca acccgctggc accattcatt
    14461 acgaaagaaa agagccaaga attcatcccc catagtgcat acgctcccca gaaaaccact
    14521 cctgcaataa aatgccaaaa atatctggaa agtgcgccaa tcaatgcacc aaacacgatg
    14581 ctttttctaa tttgtttcgt attatcgtct acatagcctt tttggacatt tgaagccatg
    14641 agccctgctg cgcctgcaaa agtataggca atcgggtact caatcaacac ttgaacgaca
    14701 cttaaataat aaacttgtcc caacggaaaa tgtaggatgc cccaaatgaa acctgccagc
    14761 atccctgcct ttgtccctct tcttaacgca aaaagagtca atggaatctg ccctaatgaa
    14821 atagaaaaac tgctgccgat ctggatcgga atcaacgaca acaccatcgc taacgctgca
    14881 acaatcgttc cttctaccca aactctattt tttcccataa aaaaacttcc tcctttgaat
    14941 aaaaaagtca caaaggagga agcagctttc gaaaatagtc aaacagctgt ttattcacaa
    15001 ttcctacgct cgcataaccg atacaggtac gaagggttta gaaatagatt caatctcagc
    15061 ccaattggac tcccctttgt gagtttattt attatttatt ttttgtttca aacaatggac
    15121 taactggttt gttttcatgg atacgtttga ttgcatctcc cattagtccg ccaacactta
    15181 cttcatcgat tttgtcgatt ttacgatctt ctggaagata gatcgagtct gtaacaacta
    15241 gacgctcgat agctgaatct tctattcttt gtaaagcagg gccggataat actggatgtg
    15301 tacatgaagc atacacacta gttgcaccag cttctttcaa agcattggca gccaatgtga
    15361 tcgtacctgc tgtatcgatc atatcatcga tcagtacaca agttttgcct ttgacttgtc
    15421 caatgatatt cattacttct gcaacatttg cttttggacg gcgtttgtct atgatcgcaa
    15481 tcggagattt caaaaattcc gctaatttac gtgcccgtgt gacaccacca tggtctggtg
    15541 aaacaacgac aacatcatcg cctttgattc ctttttctaa gaaataattg gcaataagtg
    15601 gcgcacccat caaatgatcg actggaatat caaagaaacc ttggatttgg actgcatgaa
    15661 ggtccaaagt cagcattctt gttgcaccag ctttttgaat catgtttgct actaatttcg
    15721 ctgtgattgg ttcccgtgca cgtgctttac ggtcttgacg cgcatagcca taataaggca
    15781 tgactacgtt gattgttttt gcacttgctc gtttcagtgc gtcaatcatg atcagcaact
    15841 ccatcaagtt atcattgact gggctgctcg ttgattgaat aacatagaca tgcgatccac
    15901 gaatactttc ttcaatgttt acttgaattt ctccatcact aaattgagta acagatgatt
    15961 ttcctaactc gacgccgact gctgctgcaa ttttctctgc taatgggcga ttggaattta
    16021 acgcaaaaat ttttaatctt gggtcaaagt aatgttttga catggggacc tccactttct
    16081 ttttcacaac tctagaattc tacctaataa atagtagtca tattttttaa ataaatcaag
    16141 tgattttgca aaagtcttag tttagataag ggagtttttt tgcatatcct tctttattga
    16201 cttgtcttgc tctcgcaatt gccagcgcat attctggaat attgtctgta attgttgacc
    16261 cggcagcaat cgaactgttt ttagctacct cgacaggtcc gatgatattc gtgctagaac
    16321 caataaagct gtggtcgccg acagtcgtat gatgtttgtt ctttccatca tagttgacga
    16381 agacaacacc acatccgaca ttgatttctt ctcccagcgt agcatcacca acataagtca
    16441 agtgaccgac tttagttcct ttgccgattt gagcattttt cacttccaca aagtttccga
    16501 tatggacgtt ttcgccaatt tcagcttttg gtcgtaaatg tgcataaggt cccacatctg
    16561 catgtttctt gacatggctg ctttcaatga ctgagttttc aatgacgacg tgatcctcaa
    16621 tcctactgtc tacgattttt gaatgtgacc cgatgacaca atcagaacca atgactgtat
    16681 ttccttggat ttgtacacct gcttcgatca atgtgtctgg accgatttct acgcctgcat
    16741 cgatgtatgt cgttgctgaa tcgacaaagc ttacgccatt gaccatatgc atctggttaa
    16801 ttcgctttct catgatctca tttgctttag ctaacgcgat ccgatcattg actcccattg
    16861 attcttcaaa atcatccgtt tgataagcag caactgtatg gccttcttct tttaagattt
    16921 cgatgatatc tgttagatag tattcacctt gagcattgtt tgttccaact ttgcttaacg
    16981 catcgaaaaa agcttcgttg tcaaaacagt aagttcctgt attgatttct tgtacaagag
    17041 cttcttctgg tgttgcatct ttttgttcca cgattttttc tacgatccca atatggtcac
    17101 ggatgattcg tccatatcct gttgggtttt ctgcttgtgc cgtcaagatc gttgcacttg
    17161 cattttttcc ttggtgatat tcaaaaagat tgttcagcgt ttcagtagtc aataatggtg
    17221 tatcgccact gataactaac gttgttcctt tttttccttc caagaaagaa gcagcttgca
    17281 aaacagcatg tcctgttccc aattgttctg cttgtaacgc atatttactg cgttctccta
    17341 gttgtgcttt aacttgttct gctccgtgtc caacgatcgt aatcacttca tctggtttcg
    17401 tttcactgac ccgattaatg atatgttcta ccataggttt accagaaacg ggatgtaaaa
    17461 ctttatataa ttttgacttc atgcgggtac ctttccctgc cgccaaaata attgcataac
    17521 gtgcgtccaa ctgcgtcact cctaaatata gtttgctgat ttcagtttat cccagtatac
    17581 ccattttttc aacaaaacaa gtgattttct tttatcccag cgttttctgg ataaaaaaat
    17641 agatagacca taacgggcct atctatttgg taaccggtgc tctcctgcca actcctcggt
    17701 cacaagtcac actactcata aaacatgaaa agctgttttt tgaaatcgtt tcttgtgact
    17761 tagagttaaa cggtaggctt acaacctctt cattaaacgt ttttcaatca gctgaccttc
    17821 ggtattagct caataaacgg caaaatatga ggagcaattt ttccgtttat tgagctaata
    17881 ctcaggacag gacgctgatt tcacaacctc tagataaacg gtgttcaaaa gccagtttct
    17941 cggtattaag ccaaatttat gaaaaaatgt ggaaagccat tttcacaaaa tttttcttac
    18001 tactcgaaac taagcggctt tttcacaacc tcttattctg aaaaataatt tcctggcaca
    18061 accgtaatat ttttcgtttg agtatctaca tctttgacat aaagcagtga cgtataatca
    18121 tcgatggcgc gatgaccgtt gaattttgat tcggcaaata cagtgatgcc aacaagttct
    18181 gattcgaatt cttcaatcaa gctcttcatt ccgttgactg ttccgccgcc tttcatgaaa
    18241 tcatccacta caaggacacg tgaaccacgt ttcaaacttc tcttagacag ttccatcttt
    18301 tcaattcttt cagaagatcc agacacatag ttgacactta ctgttgatcc ttctgttatt
    18361 tttgagtccc ggcgtacaat aacgaatggc gcattcagat aataggacac agcttgggca
    18421 ataggtacgc cttttgtggc tacagtcatt acagcatcga ttttttcacc aaggtattta
    18481 gaagcaatga ttcttccaac ttgacgcagc agttcaggtt ctcctaacaa atcagagaga
    18541 taaacatatc ctcctggaag cagacggtct tgttctgata gacgttctgc tagagattca
    18601 atatattttt tcgcctcttc atatgaaatt tcagggatga acaatacacc acctgcagca
    18661 cccgggattg tttccaaggt tccataccct cgttctttaa atgttttctt gatgattccc
    18721 aaatcttcac tgatagaaga tttagcagat tcataacgtt cggcaaagct tgttaaggaa
    18781 atcaattcat gcgggtgatt caataaatac tgtgtcatgt caactagacg ttcactgcga
    18841 cgtactttca cctattccaa ctccttttaa gaaattttat cgttttacat tatataagtt
    18901 tttcttcaaa aattcgagca ttttatgaaa aaataagaaa atagttcggt atttattaaa
    18961 ataaaaagaa gcctataaaa aatttttcgt ttttataagg cttcttttct ttataattta
    19021 gttatttttt cttctgaagg caaccaatat tcgtttgatg atatttacaa tcaggaacaa
    19081 agcaataaag actaatgtga ttgttgctcc tggaggtgta tctagataaa acgagctagt
    19141 tagtcctgac agcatcccta gaaatcctac acaaacactg atagcaatca cgacattgaa
    19201 gcttttgcct aatcgcatac cgattgctgc gggaagaacc atgattgcgg atatcaaaag
    19261 tgcaccggca atcgggatca tcacagcaat agccacacca gtaatcacat tgaacatcat
    19321 cgacatcaaa tgaacgggta gcccatccac gtgggcggta tcttcatcaa aagtcagaac
    19381 atacatcggc cgtttgaata aaaagaacaa tataccgatg gcaacgaata agattcctaa
    19441 aaagatgact tgctcccatg taatggtcac gatcgaacca aacagatagg attggatact
    19501 tgttgctgaa ttccctccgc tcaaattcat caatactaac gctagcgcca aaccaccagc
    19561 cattaaaatg gcaatggaga tttctgaata ggttcggtag atcgttcgca gatactccaa
    19621 tatcacagct gctaatacaa cgactagcat ggtcgtaagt gtaggattaa ggttcaaaaa
    19681 gaatcctaac gctacccctg ctaaagagac atgagaaagc gtatcagcca tcagcgattg
    19741 tcttctgatc actaaaaaca cacctagcat cggggcgatt ccggcaatga agatagcggc
    19801 aagaaacgct cttctcatga attcatatga aagcaacgcc attgagaatc ctcctttctc
    19861 accagtcgga tctgtctgtc cgcatactgt ttgatatctt catgatcatg ggtgatcatt
    19921 agaactgatt tcccatggac atgcgcacta tgtcggagaa gacgataaaa ttcatttctg
    19981 gattcttcat ccatacctgt tgttggttca tcaagaacaa ataagtcagg gtcagtagca
    20041 aaaatacgcg ctaaactgat tcgctgcttt tgtccgccag acaattcacc tattcgccga
    20101 tttcgcatat cccacatccc tacagcttct aaagcacgct gtacatgttg atgatctttt
    20161 tcagagagac gcttgaacca gcggcctctt ggatatcttc ctgaacggac taattcgatc
    20221 accgtactag gaaaacctgc attgaaagat gcaacttgtt gaggaatata accgatactt
    20281 aatttttttc cttcttgatt tttctcagca atctttatca ttccttttga aggtttcagt
    20341 aatcctaacg atgctttcac caaggttgac ttggctgctc cattttctcc agttaaaatg
    20401 acaaattcac ccgcatctac atgataagag acatcttcta gtacaggttc atcatcatag
    20461 taaaaggtca aatcagatat ttcgatataa cgcaccttac aacctccatt ctaaaactta
    20521 attgatactt tcttttaaag ctttcagatt tttttccatg acagaaatat aattttcgcc
    20581 tgctttgatt tgttcattag tcaagctttc taaaggattc aacacttcta gcttcactcc
    20641 tgtttcattc gacaatgtct cagctacctt cgaagaggca ttttcttcaa aataaatcac
    20701 tttgatgttg tttttcttca caaattcttt tagctcagct aagcgacttg gtgtgggttc
    20761 ctgatctggt gaaacgcccg aaatcgctac ttgttttaag tcgtattgat tcgctaaata
    20821 agcaaaagca gcatgctgag tgacaaatgt gcggtttgtt gcatctttta gctcatcgga
    20881 gtatttttga tccagtgctt caagcttttt gatataagca tcggcattct tcgtaaaagt
    20941 ttccttttta tctggatatt tttcgcctaa ttcttcagca atcgttctga cttcttttat
    21001 agctaatacc ggatcgagcc aaacatgtgg atcgtattca tgtgaatgac catgcccttc
    21061 ttctgattct tcatgttcgt ctgcttcttg cgattctaaa cggtcgattc ctttagctgc
    21121 ttcgatcatc aaggtctgtt tgctatccac tgaatccttt aacgaatcca caaaaaattc
    21181 catgtctgaa ctattataca cgaaaacatc tgcatcggaa atttctgctc tttcttttgc
    21241 acttggttcg aaatcatgcg gctccgttcc agcagggatc aaaagtttca cgtttccttc
    21301 atcccctacg atctcttttg taaaatcata catcggataa aaagtcgtaa cgatcgtcaa
    21361 atcctctttt ttgtctgctt ccttgttcgt atttccacat gctgcaaaca gtaaagcacc
    21421 tatcattacc gtagctgtca aaagatattt tttcatttat atgctccttt caatgaacaa
    21481 atcggaattt tacgatttat taacgtgaac taatgtatca aaataaaaaa acacagtcaa
    21541 tagaaatcca tcaatttctg atttaagcat gtatattctt gattaaatcg taaaatggat
    21601 gagttgctgc tcatatctag ccatttcact acaataaaaa actgaagaat accattttag
    21661 gattcctcag tttttcatca cctattttac ttcttatatt ttattgcagg gttcgtacta
    21721 aataaacttc ctcacaaaaa ccttttaacc cattatatac tctctgcgct cttgaataat
    21781 gttgacacaa ggcaaaaacg gttggtccgc ttccactcat caatgcagca tctgctccgt
    21841 acttgatcat acgctctttg atttgatgga tgactggatg ccgctttccc gttatatctt
    21901 ctaaactgtt tcccattttt ttgatcatct gctgataatc ttgctctcgg atggcttcag
    21961 caagtccgtg gatgtcttga tgttggatgg cttgcgtatc tacttctcta aacactgtac
    22021 gtgtagagac actcattctt ggtttgacca acacaaccca gcactgtggc atagaaggta
    22081 atacttggat ttcttcccct ttgccaccga caaatgccgt acttccgtag acacagtaag
    22141 gaacatctgt accgacttcc aaaccgattt ctgccagttc ttctaacgaa cagcccagat
    22201 tccataattg gttgatccct cttagagcag ctgcacagtc tgtacttcct ccgcctaatc
    22261 cagctgctac tggaatattc ttcttaacaa agatcttgac accggttttg atattgtatt
    22321 tattttttag caataaagca gcttgataaa cattgttccg ttcatctacc ggtaaaaatg
    22381 ctttatttgt ttctacaatg attttgtctt ctgttatttc ttcaaaaaat agatgatctg
    22441 ccaagtctac gctcgacatc accatttcca actcatgata cccatcttgc cgtctatata
    22501 atacatccag tcctaaattt atcttggctg gcgctttttc aatcaattcc atcctctcac
    22561 ccattcgaaa agtctaagtc gcaagtattc tatcataggg aaaaataaaa gtatagctta
    22621 tgtctgccta gtggttgatt ttgtcatcgt ttcaacagct ttcacagaat tttctcttca
    22681 taatccaaac aagttctagt gattcttata attctgtgag cacttcttct gccaaactcg
    22741 gaacatttcc tttttctttt cctatcagac tgagtagctg catggtagca aatccgaaat
    22801 tacttccttt cctataagca aaataacgtc cttcccaatg atcgacatat tttaatttct
    22861 tttcataagc agactggaag gaatagaaaa aattaccata attatatacg atatgcatga
    22921 ctttttcttg aaagaaagaa aaatctgttt ctccaacatt agctaatgga gctaagccta
    22981 gattggcttc cgagtagccc attttctcgt atacaataaa cagattggct aacagatagt
    23041 cagctaattc ctcagattct ttaggtaaga cccgcaacaa atcatatccc gcctgcttct
    23101 tcgtcatcgg ctgagcggtg atgaagccaa cgactttttg atctttacgg acaataccga
    23161 caccgctaga taatacatat gatttatcaa atcgtcccac agagaagtat ttttctcgtg
    23221 caccttgaag ccatttttgt gaaacttcat ttacagcttg atgtaattct tccggcagtt
    23281 gatcgtacca agtaaaatgg tatccttctt tcatcaaacg ttgatattca agttgctgac
    23341 tcagccgaga caagtcttct gttgctagat caacaatccc tgcttcacct actttcgtga
    23401 agtgaaaacc caattcatga agcatcacta cgtagctttc tgatatctta taaaacgcaa
    23461 gctgatagcc taaacaatct gcttgtttca taaactgatt cgttgctgcc cgcatcattt
    23521 taggattgcc aactggatct cctaaaacaa agcatttgtt tcctttgatc tgataaccaa
    23581 aaacgacttg atcttggtcg tcttcttggt aataaaaata actgtaacct gacaagcgaa
    23641 gctgatggct tgtagctgtg cctccgtatg tttccaataa acggtcaaaa cggtcttttt
    23701 cgtactcact gccaagcttc gtagtatctt cagctaaata ttgataaagc gccactaaag
    23761 ctagcaatga gatgcccaaa ccaataagcc ctgagaacca cacatcatct gaaggaaaca
    23821 aaataaaatg atttcctgtt attcgaccga ctaaaaagcg tccgctgtga tagcctgcaa
    23881 ttgcgtaaac gataaacaaa aagccgaaca agctagcatc aaagattata gctccccaag
    23941 aataaacgaa ttttgttcga taaaattctt ttctggataa ccacacagct aacagaatca
    24001 agacatatac caatatcaac tgccaagata acgtacgtgt gattgtattt aaaataccaa
    24061 aagatagtaa agcaatcgta ggcagaaatg cctttttgac ttttactgaa agtgctctag
    24121 caaggccgag taataaaaag ccaaccaata gattcactgt ctgatctaaa aaattgaatg
    24181 agaacggcaa taatacttga aatagccgac tgattgcaga cagattagtg attgttgata
    24241 gaagtaccat catgatcccc gcaaaataga cagcacttac gagcacgata tgcgcaacct
    24301 tttggaaaaa cagtcgcgga atgttatcta aaaatcgatt gattttgact cctgtatgtg
    24361 tgatgaacaa tagaagtccc gtcataaaag gtagaacata ataaaacaac cgataatata
    24421 atagccaaac tactgctaca tcttgccgaa cagacaattg actcattcct aagatcatca
    24481 aaacgtcaaa agtccccatt ccacctggga ccatcgtcag cattcctatc aatgtagcaa
    24541 tcatgaacat aggatagatc gaaagcatcg aaatatctat tctcatcaac ttgccgatga
    24601 tcaaaaatac cgcaagggct cccgtccatt gtccaaagga tgccagtagc agaccaagca
    24661 agccttttgg ataaaactcg aagaacaatg tctttctctt tagataagca aaaaagaaaa
    24721 tgactggtgc taaaaaacta ccgccgaaaa gccagatcca atagcttcga aaaatacttt
    24781 ctgactgaat aaaaaagaca tcaataaatg taagaaacga ccatacagac aaaccagtca
    24841 gcataaatag tgcgactttt gatacagtgg ctaaaaccat ttttctattt gtctgctttc
    24901 cataaaaact agcccgcaga cttgctccta ccacaccacc aaaaccggcg agattgttga
    24961 tcgtgtttgt tacccacgca gcaagaagaa actcttttct ttccattttt ggttttcctt
    25021 gtttttctaa gactctgatc gtcacccaat catacaacaa catcggagtg acacccagca
    25081 gtccagccag aatcatgagc aggatcgtca tgcggctttg ttgtcccatc ctttgccaaa
    25141 tatcttgcca actcatgcca ttagcaatat ttgcgacttg atttgccaca aagactaaca
    25201 cggagccgaa aaaaatcagt tttaaaatca gactatgttc ctttatccat tgcagcatca
    25261 agtatcgttt atttttcaca ttttcccatt cctaacttgt atacttttgt gtcatacccc
    25321 aatgttatct tatttatttt aatttttcca ctttagacct gttctttgct tgcgatgata
    25381 gaaaaagaaa gatatcctaa tgctaaagga gaggataaca tgaaagtagg atttatcggc
    25441 acagggaata tggcacaagc tattattgat ggtttattaa aaaaaggaac agtctcgaaa
    25501 gaagaggtgt tcgtttccag tggacatttt gaaaatgcac aaaaatttgc tgctgaaact
    25561 ggcgtccatg catgcaaaag taatcaggaa gttgcatcac aatcagatat cgttctttta
    25621 gccgtgaaac caaaaatcat tgaaaaagta ttggaagaac taagagaata tagccagaaa
    25681 gtcttattca tttctattgc ttcaggaaaa tcattaacag atttagaaac agcgcttgaa
    25741 gatcctcagg cctccatcgt acgtgtgatg ccgaatgtca atgtcagcgt aggagcaggc
    25801 gtttctgcga tttgcaaaaa tgaagctgcc acggaggaac agcttcagca agctacgatg
    25861 atttttgaag caatcggcag cgtctatcct ttagcagaat cagatttcag tacattcatt
    25921 ggccttgctg gcagctcacc cgcattcgtt tacatgctga tcgatgcgat gggacggact
    25981 ggtgtactga atggtttgtc caaacagaca gccactgaga ttgctgcaaa agcaattatg
    26041 ggttcttgtc aaaaattcct ttcaagtgat aaaaatccat gggaacttgt agaccaagtt
    26101 tcttctcctg gcggtacaac tgttgcaggt gtagttgcct tagaagaagc aggattcatc
    26161 ccagcaatca tcaaaggaat caatacgacg atcgagaaag atcttgagat gttgaataaa
    26221 aaataatgat agcaatgttt tttcgtgcct tacaaaaaaa gaagagctgt ggcttttgcc
    26281 gcggctcttc ttttgtattt tttattattt agcataatca gttgcacgag tttcccgaat
    26341 aacgattact ttgatgtgtc caggataatc cagttcttct tcgattcgtt tacgaatatc
    26401 acgtactaaa cgaacagcgt ctaaatccga gatttcttct ggcttgacca ttacccgaac
    26461 ttcgcgtcca gcttgaactg cgtaacttga ttctacaccg gcgaagctgt tcgaaatatt
    26521 ttccagactt cttaaacgac ggatgtagtt ttctaatgat tcacttcgcg caccaggtct
    26581 tgctgctgag agcgcatctg ctgcagctac aaggacagag ataacagaag tagcttccac
    26641 atctccatga tgagaagcga tcgcgttgat tactactggg ttttctttgt acttggcagc
    26701 taattccgca ccgatctcaa cgtgagatcc ttcaatctca tggtcaagtg ctttcccaat
    26761 atcatggagc aacccggcac gttttgctaa ttggatatct tcgccaagct ctgctgctaa
    26821 gataccagct aattttgcaa cctcgaccga atgcttcaag acgttttgtc cataactagt
    26881 tctgaatcgc agacgtccga tgatcttgat tagatctgga tgaagtgtat gagcaccgac
    26941 ttcaaacgct gcctcttccc cgtattcgcg aatacgttca tccatttctt tacgagattt
    27001 ctcgaccatt tcttcgatac gcgctggatg gattcgtcca tcttgtatca gtttttccaa
    27061 ggtcatccgt gcgatttctc ttcggattgg atcgaatccg gaaagaacaa ctgcttccgg
    27121 tgtatcatcg atgattaaat cgataccagt cagcgtctca agcgttcgaa tattacgacc
    27181 ttctcgtcca atgatacgac ctttcatttc atcattcgga agggtaacga ctgaaacagt
    27241 cgtttctgaa acttgatctg ctgcgcagcg ttgaatcgct aatgataata agtttttcgc
    27301 tttgcgatct gcttcttctt tggcacgctg ttcagattct tttaccatta gagttaactc
    27361 atgattcagc tcttcttcag tcgatttcat gatgacatct cgtgcgtcct cttttgataa
    27421 accagcaatt ttttctagtt ctttttgttg atcttcaatc attttttcaa cgtctttttc
    27481 tcgctcttca attaattgct gttttgaact aagtgcttct tctttacttt caagtgagtt
    27541 ctcgcgtttt tctaacgagt catctttacg attcagcgtt tgttcgcgtt gaatcaaacg
    27601 attctcttga gattttaatt ctaacttact ttctctcagc tcactttcaa cttcagaacg
    27661 gtatttctga ttttcttcct tagcttctaa caatgcttct ttttttagag tttctgcttc
    27721 tttttttgca ctatcgatga ttccagcagc tgatgattgt gcaccagcta tttctttctc
    27781 gtgacgtgac tttgcgacca taaaccctaa accaagaccg acaattaaac cgatgatagc
    27841 gaggagaatg ttgaatacca taaaatccac ctccatacta tctttttcat ttttatcatc
    27901 tatacagctt ctatgataaa ttattctaaa ctcgtcaata tgcatcttcg catatatgtg
    27961 tacaaaaaac atgcacaact ttattctaat gtttgtaccc cgtagtgtca actttaaata
    28021 aacaaagaaa cggctttcta cttattcatt aaacgatggt ttttaaaata aatgacacta
    28081 gtttcatata ggtaaacctt taaattgaga aacttttcta ttaaattatt ctttgtagat
    28141 gaacagatat ttttatttta tgtacccact cgtataatta aataactcac gatttcttta
    28201 ttcaataaaa aaacggcagg tcaaggagag tacctactct tcagaccagc cgtttttgtt
    28261 tatcataatt tttattcttc tactaaaggc aattcttctt gtcctttttc atcttctggg
    28321 acagcgactt cttcaccaat accataagct gctctaacta gagcagaaac ttctgccatc
    28381 atttcaggat gattagccat atagatttta gcgttttccc gtccttgacc aatccgatct
    28441 tctttataag aataccaagc accgctttta tcaacaatgt ctttttctac tgccatgtct
    28501 agaagttctc cttcttgtga gatccctaaa ccatacatga catctacttc agcgattttg
    28561 aaaggaggtg ctactttgtt ttttacgact ttgatctttg tacggttacc aacaatatct
    28621 gtaccttgtt tcaattgttc tgcacgacgt acttccaaac ggatcgttgc gtagaatttc
    28681 aatgcgcgtc ctccaggagt gatttctgga ttcccaaaca tcacgcctac tttttcacgg
    28741 atttggttga tgaaaatagc gattgttttt gttttgttga tcgaaccaga gagtttacgc
    28801 aatgcttgag acatcaaacg tgcttgtaac ccgacatgtg agtcacccat ttcgccgtcg
    28861 atttctgctc gtggaactaa agcagcaact gaatcgacta ctacgatatc tacagcccca
    28921 cttgatacta aagcatcagc gatctctaga ccttgttctc ctgtgtcagg ctgtgaaaga
    28981 agtagttcat cgatattcac acctaatttt tgtgcatatt gcggatctaa cgcatgctca
    29041 gcatcaatga aagcggccgt tccgccattt ttttgtactt ctgcaatagc gtgtagtgca
    29101 actgttgttt tacctgaact ttcaggtcca tatacttcga tgatacgtcc acgggggtaa
    29161 ccgccgacac ctaaagcgac atctaacgca agagagccac ttggaattgt agagatttgt
    29221 tggtcgattt tttcgcccaa tttcataata gagcctttac catagctctt ttcaattttt
    29281 ttcagtgcag catctaaggc tgctttacga tcatctgcca atacgataat cctccttata
    29341 tttacaaatc agagcaacat ttcattatcc ttatcatatc ttttttagtg aaaaaaagca
    29401 agaaaaaacc gaacaaatat tcgcatttat cattttctta aaagctgttt tctcaaaaga
    29461 tcaaatcctt gcataaccgc attatatctg atagcagcac gatctctggc aaagtgatat
    29521 ttttccgaaa ccacgccgtc tttagatgaa atagcgatcc atactgttcc tgcagattga
    29581 ccttctaacg tgtccggtcc agccactccg gtgaaagcta cactgtaatc tgttcttgct
    29641 atctcacgtg cttgaatggc catctgctcc acacattctt tgctgactgt tccatattct
    29701 gctaatagct ccggatcaat ctccagaaaa ccagcttttg tttggagcga gtaggtaacg
    29761 aatccgcctg gaaatacttc agatacacca gcaatgtcgc ctaatgcggc ttggaaggcg
    29821 ccggctgtca aactttccgc tgctgttaca gtctgcttgt tttctttcag tagttccact
    29881 acgacttttg ctagcgaatt atcatcgccg tatccataaa aatattcccc tactcgttct
    29941 tggatttttt cttctaatgc taaaagagct tgattccctg cctgaacatc atttgttttc
    30001 actgtcagtc gtaatgtcac ttcatttggt ttggcatatg gtgcgatcgt tggattgatc
    30061 tgtgtctcaa tcagatcttt tagctcagtg accagtcgcg attcaccaat cccataaaag
    30121 cgcaaaactt tagaaattag tttttcttca gaaggaaaac gttcctctag taaaggacgt
    30181 acttgttcca caaacattgg tttcaactca ttaggcggac cgggaagaag gatatacgca
    30241 tgtgtatctg tttgataaaa agtccctaaa gcaagccctg tacgatttgg tagaggaacc
    30301 ccgccttcga taatctggga ctgttgcaga ttgtttttgg tcatttttcg atgggttgtt
    30361 tcaaaatatg ccaataattt tttgtatcct tccgtatttt gtatgagaga cttaccgagg
    30421 tgagccgcag ttgcttcttt tgtcaggtca tcttctgtcg gtcctaatcc gccacataag
    30481 agtatgagtt cacttcttgt ttcagctaga gcaatcaact cttctaaacg ctgctgatta
    30541 tctcctacaa ctgtttgata ataaacttcg atacctagat cagctagctg ttctgacaag
    30601 aaagtggcat tcgtattcac gacttgtcct agtaaaagtt ctgttccgac agctattatt
    30661 tctgctttca ttacttcccg ctcccttata tagtatacgc tgtattttta tattttttta
    30721 tttaaaaaga gggcaaggag ctgtgacaaa aatcttgtca cagctccttg ttccaaataa
    30781 acagtgttct cctgccaaaa cctcggtcat aagtcacaat atacataaaa catgaaaagc
    30841 tgttttttga aattatccct tgtgactcag agttagacgg caggctcaca acctctccac
    30901 taaacgatac ttacattgat cctttgaaca caccgctgtt tttgatgaag taatccacac
    30961 ctgaatagat agtaaagatc agacaagcat aaagcatgat ttgatctact ggaataccga
    31021 tcaggctgaa tgggatatta ttgataaaca gcaagataat agcaaccatt tgtgtagccg
    31081 tcttgacttt tcccggccaa gctgcagcca tgacttctcc atgttcgaca agtagtaaac
    31141 gcaagcctgt gacggctaat tcacgacaga caatgatcgc tactacccaa ccaggggcct
    31201 ttccttggtc aaccaacatg ataaaagcag tcataactag cattttatct gccaacgggt
    31261 ccgcaaactt gccaaaatta gtgacaaggc ctcgcgcacg ggcaattttt ccatctaacc
    31321 agtctgtgat actagctaaa gcaaaaataa ctgcacctac tagctgtgtg acagccagtg
    31381 tggtgtctcc tacgttaaat tgtccccaat ctaaaggtaa acctacaacc aaaatgaaaa
    31441 tcgggatcat acaaattcta agtacagtta atttatttgg taaattcaca ctatcgactc
    31501 ctttcttccc tattctacgt gactatcagc gaagtttcca ccgatattat ttacttttcc
    31561 aaatgaattt attcaaagga gtatttttat tgaaattgat ctttttgaat taacgaagaa
    31621 ggaccgcgac acagatttgt cacgatcctt cttttttata cctacaagta aacagatgcg
    31681 taaactaatt tatacgatca ttctgcgtat tgaagagtaa ggttcacatt ttttggactc
    31741 tgattgtttt cccctggatt aactggtacg gattctccat tcgctttgat cgttgcattg
    31801 cttgctgcac caatcgtgat ggtcgcattt gttgctgttt ccggtaacac ggtactctgt
    31861 gtttcatttg ctgccagtgt cccttgataa acataggcat tgtctactag cacacctaac
    31921 catacacgat tgacagcagt aaattcaagg gttacaggct tggtagcgtc tgtgatattt
    31981 actgcgatgg cactgccaga atcttctcct gtagctattg ccattttctt ttcttcactt
    32041 gattttgttg ttgattctac tgtagaagac tctttggtct gcgtgctttg ctctgaggaa
    32101 gaggactcct cgactgatcc ttctacttta agcgaagaag ctgtgtctcc gattattgga
    32161 tcagcttgac gatcttgcca agtcatatag cccacgacaa cgacaatcgc caaagcaacc
    32221 aatcctaata aaatgacagg aagacttgtc caaaagcgac ttggatgcga ttcttcctga
    32281 tgcattgctt ttctagaagt acttactgtt tcaggctgcg gacgttcagg gaccgatcct
    32341 gtcaatttgc ttttcccatc aaaaacatcg actaaatggt ctccatcttc tcctacagct
    32401 tcagcgtatt gccgaataaa tgcccgcacg taaaatttac caggcaattg gtcaaaatca
    32461 tcattgtcga ttgcttccaa ataacgtttt tgaatttttg taatctgctg taattcatct
    32521 aaagatattt ttttattcag gcgtgcttgc cgtaattttt ctccgatggt ttcaaaagcc
    32581 actcgttcat cttctccagt ctgtttgatt ctccgaagca tctgctgttg caacgaaaga
    32641 cgttatgttt gggtgctgtg acaaaagtca tgtcacagct ccttttttcc gaataaacat
    32701 tgttctcctg ccaactcctc ggtcacaagt cacaatatcc aataaatata agaagctgtt
    32761 ttttgaactt gttccttgtg actcggagtt aaacggcagg ctcacgacct ctttcttaaa
    32821 cggtgttcaa tcagctgttc ctcggtatta gctcaaaaac cggcaaaata taaggagata
    32881 tttttccgta tgtttctcta atactcaggt caaaacgctg atttcacaac ctcttcctta
    32941 aacggtgttc aaaagcttgc atctgcggta ataagtccaa ccaagttaaa aacattaaga
    33001 agctgttttt acttggctgt tcttattact tgatgcaggg cagctttttc acaacctctt
    33061 ggtacacggt gttccagaag tagcttcttc ggcaataagc cgaaatatca caaaaatttg
    33121 agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct gaccacttct gtcacaacct
    33181 ctttgattac ttcgtttgat tttattttaa tataagttga ttaaaagaga gcatgatttg
    33241 ttttattttc tcactaattt ttccaacaca actaagaata ccataaaagc tgattttgga
    33301 ggaggttcct actacaagtc taaaacgaaa tttaagactt ttcctcataa aatactggtt
    33361 tattttggtc tcatgtaaaa ctcgctgaag gcctcttcac ttataaatgc ttccccagct
    33421 gccagtacgt ctttcatttg gatcgaatcg atgatttcag gaagatcaaa taaagttcga
    33481 tcgccaaata aactttgcgt aaattgattg gcaatatatt cgatcgaatt taatgattgg
    33541 aaatattgtc caagcatttt cttcttcagc aaatcgagat ttgtttctga cacttccgga
    33601 tcatcagcga atccaagaat gatttctttg actttttctg ctgctttctc tggttcgtcc
    33661 gtatctccgc tgaagtccgc aaagtgaaat tcacgatcca agctgaattc aaaaccaaag
    33721 ctgtcatcga taattccttg attgtacatc gctagatagt ttcgagaagt attgcctaaa
    33781 atcatttgga acaacagatt gattgctgtt ttatagcgta acagttctgt tccttcttgc
    33841 ggcaatgtgt ctaatccttt aataccaagt acaaatttat ctcgtgtaat ggctgcttcc
    33901 aatgcacttt gtttgatgat ttcttttgtg ttttcaggga aataacgtac aatttcttgc
    33961 tttggaggga aattttttgc ttcttggttt tcccgaataa gtttcatcaa tttctcaggc
    34021 tccatcttac caactacaaa taaaaccata ttgcttggct gataaaacgt ccgatagcac
    34081 gtatacaagt cttgagctgt gattttgtcg atactttcaa ccgtgcccgc aatatcgata
    34141 tgcaatgggt gtgtaggata caagttattt agtatgccaa aaaacatccg ccagttaggg
    34201 tcgtcttcat acatttggat ttcctgaccg atgattcctt tttccttgtt tacagtttct
    34261 tctgtgaagt aaggtgcttg tacaaaatcg atcagagtcg tcagattctt ttctacctga
    34321 tccgtcgtag aaaacagata gctggttttc gtaaaacttg tgaaagcatt ggcggaagct
    34381 ccttgtttcc caaataattg aaagacatca ccatcttctt tttcaaacaa cttatgttct
    34441 aaaaaatggg caattccatc tggaactttc accttttctt tttcaccata gggaataaat
    34501 tcgttatcga tcgaaccata attcgtactg aacaaaccat atgtcttgtg atagtcattt
    34561 ttaggcaaca aatacacggt caaaccgttt ggcagtactt catgataaag tgtttcattg
    34621 atttgctcat attctgtttt attcatttgc atttcctcct gctaaaaaga agattgcctg
    34681 caattcgatt tgctcagcta cttgttgtat ctctttgatc gttacgctct ccatacgttt
    34741 caaccattct tcatcagata attttgtttc cggcagccag ctgtccaaaa aagaagcttc
    34801 gattgccgct tgcggagagt ctagagaaag cagatattgg tttctcagca ttgcttttgt
    34861 ctgagacagt tccaactctg ttatttcacc atttcgcaaa ctttctaatt gctcgtgaat
    34921 cagatgaagt acttgatttc ggttcttttc atcgataccg gtttggacac tcatgaatcc
    34981 tcggaacgta tccacgctac tagaggcata ataagctaga ctttctttct ctctgacatt
    35041 catgaaaagt ttagagtgag gaaaaccgcc aaataaaccg ttaaagacca ttagcgcaaa
    35101 acgttctggt tcatcgtaat acacatttgt ctgataagct aggttcagct ttgcttgaac
    35161 gattggctca cgtacttgtc gttccttcac gatattcact tgaggttggg tataaaacag
    35221 atctggataa actgtttccc gcgactcaaa tggtaattgc ccaactgctt cagctgcttt
    35281 gtccggatca acatcgccga caacaaaaat gtcgatttga tcatttgcca tcatttcttg
    35341 atagtaggac gctagcgaac tagcagtgat cttgtccaaa tcttcgacta cgcccaaccc
    35401 tgggatcttt tgttccgggc tgttttcaaa ataaagttct tgcaaggcat aggaagcaaa
    35461 agtttgttta tcttccttca aactttccaa atatagacgc agattgttct tttccaagtc
    35521 aaacgtcaac tgatcaaact gatgattttt aatatttgga taaaataaaa cctcttttaa
    35581 aaaatctacc gcttgagaaa aaaggtttgg atcattgaca tattcaccat tcacaaaact
    35641 gatccctgcg tttagccaat gtaaatttcc tttttttcta actgataatc caaagcttgc
    35701 gccataaagc tctgcaagtt gcgcacttaa ctttgtctga tccgaataat tcaaactatt
    35761 tgtttccaac atgctgctga gaagtgaacg tttcgtgatg acttcttgtt gcagacgcgc
    35821 agtaaaacgg ataaaaatcc ggatcgtttt gtattgtttt gttggtaaga catgaagatt
    35881 cacgccttct gccaattgat acaccatatt tatatgctcc ttttcacagt tgattgcccg
    35941 cttactcttt taatgggtca acctgccttt tttacttatt cctctgcttg aaatttataa
    36001 gttcaggcaa ttcgccgttt tttctaaatg atgttacact ttatagtata gcatagatgt
    36061 tttttatcaa aagaaacaga cggctaaaag cgtatattgt ttttttattt tttatttttc
    36121 gatatactaa agacaaataa aagaagggag ggtcattcat gatcaaagaa ttcaaagagt
    36181 tcatcatgcg tggagatgtc ttggatcttg ctgtcggcgt tgttattggt agtgcgttta
    36241 caagcatcgt aaaccaagtg gtgcaaggct tgatcacacc actaataggt tggtttgtcg
    36301 caatgatcac aggtacttct gatttagaag gagcactttc aattcttgac tggtcgccga
    36361 caaaaggcgt cacatttgcg tttggtaacg ttattagtgc tatcattaca tttctgatca
    36421 ctggttttgt cttattctta gttgtcaaag cggcaaaccg tgcgaagaat ttacgctcca
    36481 aagaagagca agtggaagtg gaagaaactc ctactgcaga agattatctt agtgacatac
    36541 gcgatcttct tgccaaacaa gtggcagaag acaatacaca tccagtagag caaacaaatc
    36601 tttccgatac ttctaaataa taaagaatct aaaaaaaaga aagccgattt tcagtgtcgg
    36661 ctttcttttt ttagattctt aacttgctac ttgttccttt ttcatgtcga tatgtggaat
    36721 atcatcttcc aaatacacat ctgagattgc cttgaatcca aacgactcat aaaaagcttg
    36781 taggtattct tgtgcgccga tcacgattgg tttttctgga aaatttttct ggatcatgtt
    36841 aatcgtttct tgaacaatct ttcttcctaa accatcttta cggttgtcct gatgaacaag
    36901 gacacgtcca aaatggatac tctccgcttc ttcatatact cgcgtgtagg caaggatctt
    36961 cccatcagta tcttgaaaaa acgtatgcca agcttctcca tcaatgtcat caacttcttg
    37021 ataaggacac tgttgttcca caacaaaaac tgcgattcgt tctttgacga tcgcgtaaaa
    37081 ctctgctgtt gacaattctt caaatttctt tacctgatat tccactaagc aaacgccccc
    37141 tgctttttta ttcttagcat accgattcgc acacaaaaaa gcaaacgaac cttacgaatc
    37201 tcaggctcgt ttgcttttta aactgcttca gttaaaaatt cgatctcaac tgtccgagta
    37261 agtacatctg aatagctgta agatactcgt tcaaaagaat tttcttcagg atccaaatca
    37321 acaacgaata ctgaaggata ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt
    37381 cttcctgtct gagcaaccaa catgattggg ctgccgatac gaccttctaa atctttcttg
    37441 attgaagcta aagttgttgg catacagttc acctctacta tcaactatac cacatatttt
    37501 taaaattttc aagtttacca taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc
    37561 attaagattt ttctaaatta ttcctcatta taaaatttca agtgtttttt tattttgagt
    37621 tttactctcc cgtaagcgct cattacttgc ttgtgatcca ttgctaaaca ttcagccatg
    37681 tctacaaaat caacgccttg catataataa tgaaaaattt tagcttctat ttttgaaaac
    37741 tggatttcgc aattttcgat tgcttctttt aataaaagat gctgaattgc taaaggttct
    37801 tgcaatgtga tctctgctaa aaagtctggt ccttctgtct ctattttttg gtcgattgag
    37861 acttcatctt tttgatcacg acgcttcagc gcgttctgct tcctcaacag agaatagatt
    37921 tgattgctta taacgctttt ataataactt ccaaagctaa cacctttgct tttttcgtaa
    37981 gttctcaatg cctgatataa agcgatcctt gcttcttgtt cccaatcctc agaaacataa
    38041 tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg
    38101 gcagcaaatg cttcttcgtc accattacgt gcagcgcgca ataactcctc agacataaaa
    38161 taattcctcc ataaattcgt ttatggagga atcttatcat caatgattca tcgaactgat
    38221 tagaacgata tgttatttat tttttctcat taaatcgtcc aatttttggg acaatttttt
    38281 taactgctct tcattccatg gagaattacg tcggaaatca ataaaatgca tatctttatt
    38341 ttcttgggct attgtttttt ccgttttttt tatcgtctta tataattcat aagcagaagt
    38401 tcgtaatgct ccttgggaaa agatcatcca ctgttctgct aaatcgcttg tcgccactgt
    38461 cacttgtgtc aaacggtcat tcagctgacc agcgattctc tcgatataac tgtcagccgt
    38521 ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc ttataatttt gttggatgcc
    38581 cggaactagt tgggcatcga agacaacgat gacttccatt ccttcatatt tcgcataatt
    38641 tgataaacga tgtaaaagag cttctcttgc atccgccatt ttgtcctgct ttttaagctg
    38701 gacaagttcc ggccacgaac caatcatgtt gtagccgtct acaatcaaca gctgtttttt
    38761 catggtctac tccccctgac gttgggaaaa agcctgatac ataagcaaac cagcagcaac
    38821 actggcattt aagctctgga cgtgcccggt catcgggatc gtcagcaatt catccatttc
    38881 ttttttcaat cctggactca ttcctttgcc ttcattacca atgactaaag caattgatcc
    38941 tttggcattc catttttgga agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc
    39001 tgtttctttg agctgttgca cagcttgtac caaattcgtc acgcgtgcaa cagggacatg
    39061 ttcgactgcc ccagtggaag tctttgttac gataggtgtg attccaactg ctcggtgttt
    39121 tggtatgatc acaccatcga cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt
    39181 gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt
    39241 tcgttcaatc agttggtcaa gggataaata ttcataaggt gtaatcgcaa gaacgactcc
    39301 ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt ttaggaaccc atttgactgg
    39361 cacagcttgt tcacgtgcga tttctttcag ttcttctact ttttctcctc gtgaatcttc
    39421 ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct tctactgcgg catggtgccc
    39481 aaagacgaaa ttatcttcta atgcttcttc attttgatca gaaactgact gatttcgtcc
    39541 agtttgcttt ttatttgaat atctattttg ttttttgtct tcaaatccac gtttcgattg
    39601 atgtttgttt gttctttctt tacccatttt tttcaccaac tttctgaata caccagcgga
    39661 tcaattcttc catccgctcg gtttgttttg tcaaatgcag atagcccatg agcgcttcga
    39721 accctgttgc gacccgatac gtcgtaacat cagcattttt tgcgctcgta tggcttttag
    39781 catttcttcc tctgcgataa taaagttctt cttcttctgt caaaagatgt tcttccagca
    39841 tttgctgaat caaaaaggct tgtgcattcg cagaaacata attcgttgcc gcacgatgca
    39901 gcttattggg ttttgtttct ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa
    39961 tcgcatctcc aacataagcc aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc
    40021 tcttctccat cgggttcctt gcggtgtatc ttctaataag atcccttttt ctttcaacaa
    40081 atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt cttgcttgat ttcgttcttc
    40141 gatcaattgt tcaatctctt catctaataa ctcttctgct gtaaataaaa taccgaagat
    40201 cgaaagccat tgcgagaata aagcttctcc ttgtgccaag acagcggcag aaactttcgg
    40261 ctggtctaga taagtgttca gccacttagc aagctcatag accactgtga tcccatttgc
    40321 tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc
    40381 gattttatcc gcatcatctg ccaaattctc tgaggcagtt tcttggcgga atttcaaatt
    40441 gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct tctttcatcg tcgtttcact
    40501 gtagcggatc ggacgacggt attgtgtggt cgccatgaag aaacgcaaga cttgtggatc
    40561 aacgtttttg atcatttcat gtacagtgat gaaattccct agagatttac tcattttttc
    40621 atcgtcttcg ccaatcgtta catagccatt gtgcatccag taattagcga attttttccc
    40681 tgttttcgct tcactttgtg cgatttcatt ttcatgatga ggaaattcta aatcttgccc
    40741 gccaccatgg atatcgatcg tttctcctaa atgttttgtt gccataacgg aacattcaat
    40801 atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa gaaatctcgc caggttttgc
    40861 ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc tgctgttctt cccctgtacg
    40921 ctgacttgct ccgacttcca gttcatcgat ggattggtca cttaatttcc cataattttc
    40981 aaatttacgg gtacggtaat acacatcacc tgaagattca taagcatagc ctttttcaac
    41041 caacacttga ataaatgcta aaatatctgg catatgatcc atgactcttg gatgcagtgt
    41101 agcaggttcg acattcaacg ctttcgtatc ttcttcaaat gctcggatga aacgatcagc
    41161 aacttctggt gctgtaatac ctaattcgtt tgctgtacgg atgattttat cgtctacatc
    41221 cgtgaaattc gatacgaaat cgactttata gcctcgatat tcaaaatagc gtcgaattgt
    41281 atcgaaagca atggtgctac gagcatttcc gatatggata taattataca cagtcggtcc
    41341 gcagacatac ataccgacat gtcccttttg tatagggatg aattcttctt tttttctggt
    41401 caatgtattg tagattttta tcattctgat ctcctcactt tttctccttt gattcgaacg
    41461 acttttgctg gtactcctac cgctgtagcg tcgtctggaa catctttcaa cacaacggca
    41521 cctgcaccga ttttggcgtt ttttccgatc gttaccggtc ctaatatctg cgcattcgca
    41581 gagagcatgg ctccttgttt aacagttggg tgtcttttac ccgtttcttt tcctgtgccg
    41641 cctaatgtta cgccatggaa taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg
    41701 acgattccca ttccatggtc gatgaacacg ccagttccaa tcgttgctcc tggatggatc
    41761 tcaacaccag ttaggaaacg ccagaattga gcattgatct tcgccaataa aaagagccgg
    41821 tgctgatata aaaaatgaga gaaacgatgc caaaacaagg catgaaaacc agggtatgtc
    41881 aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct
    41941 cgggtaaacc aactcatgac tttccactcc tttcgtaaga attttatgta ggaaatcatc
    42001 ttcttataaa gaaaagaagc gccttttaaa taagtttcct tatcaaaaga cgctttccgc
    42061 gtggttccac ttttcttcat aatcaatgat tatctctgac agctaacgcc tgttatacgt
    42121 tcttggctac tttgtttcct ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc
    42181 actcccagag gcatttcggc aaccattcat tgataccttg caccacccgg tatctctctt
    42241 gtaatgatca gctgcttact tttttctgtt catcgtgttt agttcagtac ttgatttaaa
    42301 tgtgctaatg atttttcacg accaagcaat tcgatcgttt caggcaattc tggaccatgc
    42361 atttgtcctg atacagctac acggattggc atgaaaagat tttttccttt tacgccagtt
    42421 tctttttgaa cagctttgat ggcagctttg acagttggag catctactac ttccatttgt
    42481 tctagctgtg ctttgaatgc gtggagaaca gtaggaactg tttcaccagc aagtacttct
    42541 tttgctgctt cattcaatac aggatgttca ttgaaaaata gcgtagacag atcaacgatt
    42601 tctgcagcat agctcatttg aggttgatac aggctaacga tcttcttcac ccattcgatt
    42661 gtcttttcat ctgggttttc tgctacacgt ccatcagcga ttagataagg cagacacatg
    42721 tcagtaaatg catctagatc cattgctttg atgtaatggt tgtttaccca ttgcagtttt
    42781 ttcgcatcga aagctgcggg tgatttactt aggcgttttg gatcgaacat tttgatcaat
    42841 tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc agcccaataa tgcaataaag
    42901 ttgaacattg catctggtag atagcctaat tcgcgatatt gttcgataaa ttgcaagatt
    42961 gattcgtcac gtttgcttag ttttttacct gtttcactgt tgatgatcaa tgtcatatgt
    43021 ccgaaggttg gtggtgtcca gccaaatgct tcatagatca tcagttgttt tggtgtattg
    43081 gcaatatggt catctccacg taaaacgtga gtgattttca tcaaatgatc atcgaccgca
    43141 acagcaaaat tataagttgg cataccatcg cgtttttgga tgacaaagtc gccaccgata
    43201 ttatcggatt cgaacgaaat agcgcctttc accatatctg taaatgcgta ttctgtattg
    43261 cgaggcacac ggaaacgtac aacagattct agaccttgtg cttctttttc tgcttgttct
    43321 tcaggtgtca agttcgcaca tgttcctgcg taatgaggca tttctcctct tgcgcgttgt
    43381 gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc atttgtatgc tcgattgcta
    43441 gcaagcagct gatcaatcag cggttgatag atttctttac gttcagattg acggtaaggg
    43501 ccgtattctc caggattttc aggagattca tcccaattca ttcccaacca agcaaggttt
    43561 tccaactggc ttttttcgcc atcttcgata ttacgttttt ggtcagtatc ctcaatacga
    43621 ataataaagt ctccatcatt gtggcgggca aacaaataat tgaataatgc agttcttgca
    43681 tttccaatat gcaggtgccc agttggactt ggtgcatagc gtacgcgtac tttcgtcatt
    43741 ttcttcctct tctttcaaac tagactttga ctaacagcaa aaattccgtc agttacggct
    43801 tctcaaatat catttattta aagccactca gcacaaattt taccttttct aaggtaaata
    43861 gtaaagccaa ctggttgaat ttccttacca gttggctgaa tttctttttt attttgattg
    43921 tttagtcttt ttctctgtct cttttttatt gtcgattcct cgtcctgcat gtgcaggttt
    43981 agcaaagatc atgcgtccag cagctgtttg aagggcactt gttacaacga cttcgatacg
    44041 ttcattcatg taatgctgtc catcttctac gacaaccatc gtgccgtcat caaggtaggc
    44101 tactccttgt tggcgttctg tcccggcttt tactactaga acattcatcg tttcaccagg
    44161 gatgacgact ggttttacgg catttgccaa cgcattgata ttaagaacag gtacattttg
    44221 gaattcagag actttattca agttatagtc attggttaca atgacaccat ctaaaagctt
    44281 agccaatttg atcaatttgc tgtctacttc actgatatct tcaaagtctc catcgtacat
    44341 ttcgacagat ataccctctt ctttttgcaa ggcatttagg atatctaatc cgcgacgacc
    44401 acgcacacgt ttcaaactat cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa
    44461 attagggatc atcaaggttc cttctaagaa tccagtcttt gtaatatcat aaatccgacc
    44521 gtcaatgatc acgcttgtat ccaagatttt atatttatgg aaattttctc ctgattttcg
    44581 ttctaacagt tgactctcaa cttgactagc tgtttcttgc tcgatttttt tgcttcgtga
    44641 accaaaaact ttcttccatt cttcgattcg tgtcgttccc attctcaatc ccagatagcc
    44701 taagatgatc atcagtaaaa tcggcaatac actattgacg aatggaattt ccatattgta
    44761 aagaggggtc gagatcacaa cacctaaagt caatccgatg atcgcaccga tcgcaccgaa
    44821 gagaagataa gtcaagctga cctcacttag tttttgttct acttgtttga taatagctga
    44881 gatatgtttg gccaacagca aagataataa aaagaaaata agtgcgccta acaggctgtt
    44941 ggtaaatgta ttattcagcc atccgtttga ctgttgaccg attgcctgcc aagctgaggg
    45001 taaaaatgaa atacccaagc ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt
    45061 ttgcatcgtt tttcctccgt ttcgacaatc atttattagt tagcggaaca cacgcttcaa
    45121 cgtttcagcc aaagttgcta ctccaactat ctcgattcct tttggcgctt cccagttacc
    45181 taagttgttt ttaggtaggt atacttttgt gaagccgagt ttttggactt ctttgactcg
    45241 ttgttcaata tgactgacac gtctgatttc tccagtcagt ccaatttcac cgatgaaaca
    45301 ttccgttggc tgtgttcctt tttctttata gcttgaagca atactgacag cgatagctaa
    45361 atcaatcgct ggttcattta attttacccc acctgcagct tttaagtaag catcttgatt
    45421 ctgaagaagc aacccagctc ttttttccag cactgccatg atcagagata cccgattgaa
    45481 atcaagacct gttgttgttc gtttggcatt tccgaacata gtaggtgtga ctaatgcttg
    45541 gatctctacc aaaattggac gtgtcccttc cattgccaca acgatagcag agccagttgc
    45601 accgtctagg cgttcttcta agaaaatctg tgaaggatta gcgacttctt ccaatccatg
    45661 ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca aatcggtttt ttactgctcg
    45721 caaaatccga aaactatgat gttgttcacc ttcaaaatat aacaccgtat ccaccatatg
    45781 ttctaacatt cttgggccgg cgatcgagcc ttctttggta acatgaccga cgataaaaat
    45841 ggctatccca tttgttttag cggttttgag tagttctgca gtggtttctc ttacttggct
    45901 gacacttcct gccacacttg tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat
    45961 aacataatca ggggagatat gttcgatggc acgactgatt tcgttcatat ctgtttcagc
    46021 gtatagataa aattctgtgt tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc
    46081 tgcgctttct tcgccggata catataagac ttttccgcct atggctgcta attgctgaga
    46141 aacttgtaac agcaaagtgg atttcccgat acctggatcg ccaccaatca agaccataga
    46201 ccctggcacc acacctccgc ctaacacacg gttcagttct tctaattttg ttttgatccg
    46261 aggttctttt ttagggacga cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa
    46321 acttgtccga gttctgcggt ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca
    46381 ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac acatacccgc aattttggca
    46441 aacaaattgt acttttgatt tttttgccat tgtaccgcct ccttttatcc taatcatgag
    46501 acattaaatc aagcttaagt atctttaacg ttttatttac tggaagaacc aaatccgcct
    46561 tgacgttgag cagtcgtttg atcttgatct gcttttaaaa acggcaaaaa gatcccttgg
    46621 ccgatacgct cgcctttttt gatcactaca tccttgaaac caaagttggt gaattggaac
    46681 atgatatggc cttcatttgc ctcattattg taataatcac tgtcaatcac acctactccg
    46741 tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat
    46801 tcatcttctc ccatgtaagc tttgattcca gtaggcacga gggttggttt caattgtttt
    46861 tcattttctg atacatcttt tttcaatcca tctgcgactg tttccaaccc ctttttccag
    46921 cctgctttcc agatacttgg aatcacgacc tcttctgctg cttcaaaatc atagccagca
    46981 gcatgatgtg tagcgcgctg cggtagattg atattttgat ctttatattt agaaataact
    47041 tcaaatcctc tttttctcac cggttttcct
//
LOCUS       DAPBBV010000025        40855 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.025, whole genome shotgun sequence.
ACCESSION   DAPBBV010000025 DAPBBV010000000
VERSION     DAPBBV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.025"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            210..1016
                     /gene="proB"
                     /locus_tag="RD486_001620"
     CDS             210..1016
                     /gene="proB"
                     /locus_tag="RD486_001620"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDT7663355.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1013..2260
                     /locus_tag="RD486_001621"
     CDS             1013..2260
                     /locus_tag="RD486_001621"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDT7663356.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2336..2680
                     /locus_tag="RD486_001622"
     CDS             2336..2680
                     /locus_tag="RD486_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663357.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2797..3123)
                     /locus_tag="RD486_001623"
     CDS             complement(2797..3123)
                     /locus_tag="RD486_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663358.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3738..4940)
                     /locus_tag="RD486_001624"
     CDS             complement(3738..4940)
                     /locus_tag="RD486_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7663359.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            5057..5572
                     /locus_tag="RD486_001625"
     CDS             5057..5572
                     /locus_tag="RD486_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7663360.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5771..6217)
                     /locus_tag="RD486_001626"
     CDS             complement(5771..6217)
                     /locus_tag="RD486_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDT7663361.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6264..7742)
                     /gene="msr(C)"
                     /locus_tag="RD486_001627"
     CDS             complement(6264..7742)
                     /gene="msr(C)"
                     /locus_tag="RD486_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDT7663362.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(8096..8725)
                     /locus_tag="RD486_001628"
     CDS             complement(8096..8725)
                     /locus_tag="RD486_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7663363.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(8709..9173)
                     /locus_tag="RD486_001629"
     CDS             complement(8709..9173)
                     /locus_tag="RD486_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7663364.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9660..10928)
                     /locus_tag="RD486_001630"
     CDS             complement(9660..10928)
                     /locus_tag="RD486_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7663365.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(11159..11896)
                     /locus_tag="RD486_001631"
     CDS             complement(11159..11896)
                     /locus_tag="RD486_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7663366.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11963..12532)
                     /locus_tag="RD486_001632"
     CDS             complement(11963..12532)
                     /locus_tag="RD486_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDT7663367.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12660..13532
                     /locus_tag="RD486_001633"
     CDS             12660..13532
                     /locus_tag="RD486_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7663368.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13874..14746
                     /locus_tag="RD486_001634"
     CDS             13874..14746
                     /locus_tag="RD486_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7663369.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14743..16701
                     /locus_tag="RD486_001635"
     CDS             14743..16701
                     /locus_tag="RD486_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7663370.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(17033..17884)
                     /locus_tag="RD486_001636"
     CDS             complement(17033..17884)
                     /locus_tag="RD486_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7663371.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            18007..18474
                     /locus_tag="RD486_001637"
     CDS             18007..18474
                     /locus_tag="RD486_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDT7663372.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18737..19219)
                     /locus_tag="RD486_001638"
     CDS             complement(18737..19219)
                     /locus_tag="RD486_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDT7663373.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(19319..20182)
                     /locus_tag="RD486_001639"
     CDS             complement(19319..20182)
                     /locus_tag="RD486_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7663374.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            20780..21655
                     /locus_tag="RD486_001640"
     CDS             20780..21655
                     /locus_tag="RD486_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663375.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(21800..21952)
                     /locus_tag="RD486_001641"
                     /pseudo
     CDS             complement(21800..21952)
                     /locus_tag="RD486_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(22220..23551)
                     /locus_tag="RD486_001642"
     CDS             complement(22220..23551)
                     /locus_tag="RD486_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7663376.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(23700..24413)
                     /locus_tag="RD486_001643"
     CDS             complement(23700..24413)
                     /locus_tag="RD486_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7663377.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            24588..26012
                     /locus_tag="RD486_001644"
     CDS             24588..26012
                     /locus_tag="RD486_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7663378.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            26311..27018
                     /locus_tag="RD486_001645"
     CDS             26311..27018
                     /locus_tag="RD486_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDT7663379.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            27005..27328
                     /locus_tag="RD486_001646"
     CDS             27005..27328
                     /locus_tag="RD486_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDT7663380.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(27417..28454)
                     /locus_tag="RD486_001647"
     CDS             complement(27417..28454)
                     /locus_tag="RD486_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7663381.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(28775..29758)
                     /locus_tag="RD486_001648"
     CDS             complement(28775..29758)
                     /locus_tag="RD486_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HDT7663382.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(30173..30943)
                     /locus_tag="RD486_001649"
     CDS             complement(30173..30943)
                     /locus_tag="RD486_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663383.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(30936..31871)
                     /locus_tag="RD486_001650"
     CDS             complement(30936..31871)
                     /locus_tag="RD486_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663384.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(32187..33836)
                     /locus_tag="RD486_001651"
     CDS             complement(32187..33836)
                     /locus_tag="RD486_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDT7663385.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(33953..36556)
                     /locus_tag="RD486_001652"
     CDS             complement(33953..36556)
                     /locus_tag="RD486_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDT7663386.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(36568..37617)
                     /locus_tag="RD486_001653"
     CDS             complement(36568..37617)
                     /locus_tag="RD486_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDT7663387.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(37643..37957)
                     /locus_tag="RD486_001654"
     CDS             complement(37643..37957)
                     /locus_tag="RD486_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDT7663388.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(37973..38419)
                     /locus_tag="RD486_001655"
     CDS             complement(37973..38419)
                     /locus_tag="RD486_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7663389.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(38420..40342)
                     /locus_tag="RD486_001656"
     CDS             complement(38420..40342)
                     /locus_tag="RD486_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDT7663390.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            40630..>40855
                     /locus_tag="RD486_001657"
     CDS             40630..>40855
                     /locus_tag="RD486_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HDT7663391.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVC"
BASE COUNT        12421 a         8259 c         7017 g        13158 t
ORIGIN      
        1 actactccta ttctaacata tccgaggctg taaaagactt tctttacaaa ttcttcaaga
       61 aattctgcta tcttaaagta aaccattaat tcgttctttt tccaaacgac tgcaagttgt
      121 acaaaaaaac tattttttac atgactttac tcgtcaaaac aagtagaata gaacgaaatt
      181 aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa
      241 ttattgtcaa agtaggaaca agtacattga tttatcccaa tggaaatatc aatcttgcgg
      301 caatcgatca gttagctttt gtcctttctg atcttagaaa tcggggaaag gaagtgatct
      361 tagtctcatc aggagctgta ggcgttggta tgcataaatt acatttgtca gaacgtccga
      421 ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca agccgaactg atgaatatct
      481 ataatcaaag attcagtgta tataatcaac agacggcaca gatcctcgtg acaagagacg
      541 tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac attggaacag cttttgatta
      601 tggacacgat ccctatcgtg aacgaaaacg atactgtagc agtggatgaa ttagatcatc
      661 tgacaaaatt tggcgataat gatcagctgt cagccatcat ggcaaaactt gtcgcggcag
      721 accttttgat cgtcctttct gatatcgacg ggttttattc agataatccg actacaaatc
      781 ccgaggctca gatgtatcgc tatatcgata aaatcgatga aaagattctg gcacaagcag
      841 gtggtgctgg tagcacattt ggaacaggcg gtatgcagag taaattaaaa gccgcttcta
      901 ggatatttga agcaaacagc gcaatgattt tagcaaatgg aaaaaatccg gcaattattt
      961 ttgatattct tgcaggaaaa gaagtaggta ctttatttaa ggaggacttg aaatgactga
     1021 cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa caactagcac ttatgcctac
     1081 aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc
     1141 gatcattgaa gcaaatcata aagacttaga aaaagcagtc gaaaacaata tcagtgaaac
     1201 gatgcaagac cgcttgcagc tgacacctga gcgaatcaat gccatggcta cagagatcga
     1261 aaaaattgct tcgttagacg atcctattgg aaaagtagat gagatgtgga cgaacaccga
     1321 cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg atcggcatca tttacgaatc
     1381 tcgtccaaat gtcacgacag atgcagctag tctagcattc aaatcaggga atgccgttat
     1441 ccttcgcggt ggcaaagaag cattcttctc gaatcaatta ttagtccaat tattgcagca
     1501 agtactggtc agtgctggcg aatctcctta tgccatccag tttgtcgatg atacttctca
     1561 tgaaactgca ggacagttga tgcgattgac agaatactta gatgtgctga ttcctcgagg
     1621 cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg gtacctatca ttgaaacagg
     1681 tacaggaaat aatcacgtat atatcgataa agaagcacag ttatctatgg cagtgaacat
     1741 catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac gcggcagaaa cattgctgat
     1801 ccattctgag atcgcacctt ttttcttgcc agctattgaa aaagaactgg tagaacacgg
     1861 ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta gagacggctg ctttagcaga
     1921 agacacagat tgggatactg aatatctaga ttatatcctt gctgtcaaag tggtcgattc
     1981 tttggatgaa gcaattgcac atatcaatcg gcataatact aaacattcag aaacgatcgt
     2041 gacagatagt tatgcggcta gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta
     2101 tgtcaatgcc tccactcgtt ttacagacgg atcggtattt ggttttggtg cagagattgg
     2161 tatctctact caaaagttgc atgcccgtgg tccaatgggg ttaaatgaat taacttccac
     2221 aaaatatatc atttatggcg atggacaaat ccgcgaataa tgtttcgtgt gaaacattat
     2281 tcccgccttt tgcctttttt ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt
     2341 tgaaatttta atgatttttt ttatttacct tatttctctg aatatcgctg cttttctggg
     2401 agtcggtatt ttatcccttt tctttcaatt caaaaaacga agcataggga gtcaacggga
     2461 aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat
     2521 tagttacatg gttgcattat gcttattagc gacaatcaat tactattctt ttttcgatca
     2581 ttcaatcgct tatacgatta cgctactgat tgctgggatt tttcacttat cttataaata
     2641 tcagctgaat aaaaaccact tgaatcggac tttccgctaa aaaatatccg tacgataagt
     2701 agagtgcctt gaagatcggc aaaaaactgc cggacttttt agaggctgtg acaaagattt
     2761 tgtcacagcc tctttttcca tataaacggc gttcgcctac cagctgcctg gtaaatctgt
     2821 ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg ccatcataat aacgaagcag
     2881 ctcatccatg gacaagttca tcgttttttc tttttcttct tccgctgatt cagccagtag
     2941 ctgttcccga tacacctgat acataccagc tattttttgc tgcatcgctt ttctagtttc
     3001 accttccgca ttgattattg gcaattcttt gatatagcca cgataaatca accgatcatc
     3061 tgaaaattca atgggtaatt caacgagtgt caacccgact tcctgaaaat attcttccag
     3121 catctattat ccccccattc tttttcttaa atgaatttta gcttacctac tgaaaatttt
     3181 ccagtttcat tattttgaga aaaaaaggga atgtgacaaa aatcgtgtca catccccttt
     3241 ttccgaataa atggtgttct tctgccaact cctcaatcat aagtcacaat attcaacaaa
     3301 catgagaaac tgttttttga aattgttcct tgtgattcag agttaaacga cagtctcaca
     3361 acctcttggt aaacggcgtt caatcagctg accctcggta ttagctcaaa aaacggtaaa
     3421 atatgagaag ctatttttcc gttttgtttc tctaatactt aggataaaac gctgatttta
     3481 caacctctgt taaacggtgt tcaatcagct gtccttcggt attagctcaa aaaacggcaa
     3541 aatatgagga actatttttc cgtttgtttc tctaatactc aggacaaaac gctgatttta
     3601 caacctcctg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
     3661 aaaaatatga gaagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
     3721 tcacaacctc tgatttctta ttcttcttca tttgtagcaa aataattacg gtgataaatg
     3781 atacaacata cactgataag aacaatggca cctgcaaaat aaaacgcata gctttcacca
     3841 atatgttcac caatcacacc tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca
     3901 aaactatagc tggacgaagc aacgtttcgt tgcagacctg gtatttccat agcaatcgtc
     3961 gtcaacagtg tattgataat tccttggaaa aatcctgcta acacaatgct gatcggtaca
     4021 aggactggca tagaagttcc agctcctaat aacagcaaac aaataatgaa taagacaaat
     4081 gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc
     4141 gaagcaatag ccagaagcac accccagcca aaaaatacaa aaccgacttc taattcagaa
     4201 tagccaatca ataaaaatgg cgcatacgca agtaaagtaa agaatccgaa attatataac
     4261 aatgcgatta gtccaactga acgaagttta tgattgctta acgctttgac accttcccaa
     4321 aggcctactt ttctctttgg tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa
     4381 ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac gccatgaacc actgcccaag
     4441 accccaccga ctagagggcc aacagccatt ccgcagccaa gtgctgcttc atacatcatg
     4501 attgcttttt ctgtgttacc aactaaaata ctgacgatcg ttgctaaagc agtagagaca
     4561 aataaagcat tcccgacacc ccagccggca cgtaacccaa tcagcattcc gatattccca
     4621 gataatccgc caagaccagc gaatacaacg atgataaaca atcctgtcat caatgttttt
     4681 ttcaaaccga tccgactaga taagaaacct gtaaatagca tcaccacacc agtgactaac
     4741 atgtaactag taaataacag ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc
     4801 gtttttaaga ttgggtctac tagacccact cccataaaag cgatcataca ggtagctgct
     4861 acaactagcg ctgaactttt cccctttgtt tcttcatttg tttgttcttg tatatctatt
     4921 tgattctcca atatttccat ccctttctct ctattagcat catacatgat ttattttaca
     4981 tgtcaatatg cacatgtaaa acgtggaaac tttactgtga tataataaag aaaataagac
     5041 gagaggtagg atttttatga atactttagc ctatatatta ttatgcgtgc ttttatccaa
     5101 accacgttct gggtatgaat tgaagcagct gatcacaatt ttttgggaag cccatcacag
     5161 tcagatctat acaacgcttg ccaagttaga ccagcagggt tatgtgaccg ttttggacaa
     5221 agacgagcac tctcaaaaaa agatctacca cttgactgat gaaggacgtg ctcttgtaga
     5281 ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat
     5341 ctatgctttt tcgacgctcg ataaaacaac agctactgga ctgctattca ctagagaaca
     5401 acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg aatgacctct cgctagacaa
     5461 gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga attatgcttt gtcagcagga
     5521 actccaatgg tgtcagcaag taagagaaca aatgcagcag ttttttgagt aagggataaa
     5581 cagaaccttt ctagaaatat ctattgaaga gcaaattatc ttcaataaaa gagcaataca
     5641 gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc tatcgttcgg atcactattt
     5701 ttctagaact gcattcaaga gactatgaca aaaagcatgc caaggccttt tttcaaataa
     5761 cagtgttcca tcattcatta ctttgaattg cttttagcac acttcttgaa agcgggccaa
     5821 cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat tttccaagca ttcatataag
     5881 cagagaataa ttgatcaggt attccttgtt ccatgatcac accgaataaa gacatacatg
     5941 tcaccattcc taaaaccatc aagcatgaaa tagttaagat catttggacc ttgctttctg
     6001 gatttactgg tagtttaaag gcaatttttt tcgccagcac accgatgatg aagacatcca
     6061 aaatgaaagc caccacgaat ccaggcacta gaccaatcaa caaacttgat aaatgaagat
     6121 cttgatgcag ccataaatta tacgcgctca tccccaagac catcaaaaaa cacatcattg
     6181 ttgtaaaaat tattccttct tttttatttg taggcaatct gtaccactcc tttaaatttg
     6241 tcacgaaaat catcgtagca catttaaaaa tttctcgtaa gtactttttt tattttctgc
     6301 ccttttattt cataaacttc atcagccgta cgctcgacaa agtaagaatc atgagaagta
     6361 aacaaaatcg ttcccggata tatttgcatt agcttctcta aagcttcgat cgttgccata
     6421 tcaataaaat tagtcggttc atctaacagc aacacattac ttggcttagt aaaaagcaaa
     6481 gcaatcgtca gacgggtcgc ttctccccca cttaatgtac ataacggttt cgtcaaagtt
     6541 tcctgagcaa accctaagtg attcagcaaa ctacggacaa gcgattctga aaactctgtt
     6601 tgtctcatga caaaacgaat gatggattct tcagatgtca tttgataacc cttttgctga
     6661 tatacttgaa agcttacttt cggagagaga aggattcctt ctccttgttt gcggatatgt
     6721 tctaataagg ttgtcttacc tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa
     6781 gaaaactgaa aatcaccatt taccagtaat gttctcccac ttctttccaa ttggacattt
     6841 tgtcccatga tgggatagcg gctgtggagt tcaagagatt ttggtactgg aaaacggatt
     6901 tgtttcatct gctgcggctt ggttgtttct cctatttttt ggagtcttct ctctaatgtt
     6961 ttcgcattct tttggatggc tttttgtaca ctgtcttttt gtttagagga agacaaccga
     7021 tccagtctga tttgttgctt tttcttttta ctggacactt tttccaactt ttccgcttgt
     7081 tttttctttt cttggatcga tttttccaat cgttttttct ctttcatgat cgactctgct
     7141 tctcgtagct gagtcttttt ctccaattcc ttttgagtga gataggcact ataattcccc
     7201 gaaaactctc ggatttctcc gtcttttact tcccagattt tcgatgctag ctcatctaga
     7261 aaatagcgat catgactaac aaaaaccagc gtaccataat aataacgaag ctcttcaatc
     7321 agtcgatcaa tactttttct atctagatgg gttgttggct cgtctagaag catcccttgt
     7381 tcataagaag aaagaagacg tatcaactcg atctttcgtt cttcccctcc gctccatttc
     7441 cgctctgaag tttcttccag tcttaactgg aaatgactgg ctaattccaa atttaggtcc
     7501 tttgcttcag cgagataggt taattgaggc aggtagttga aggtgatctc tgtttggatt
     7561 ttcccatgat cgggaaaaag ttcaccggct attagtttga gcaaagtcga tttaccgaca
     7621 ccattttctc ctatgatccc tatacgatct tgctgataga cacgaagaga atcaatagat
     7681 agttctagct ggttgccaaa gctgacttgt agatttgtta tatttactgc taaattttcc
     7741 atatgtttta cactcctatt tcatgtaaaa caacaattat cgatactaaa aaagagcaga
     7801 aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta ctctgaacga aataactatg
     7861 actaaatcac caaatctgtc atagctttca cctattctac tgtcgttcga aaaaatggac
     7921 atactccatc catgaaattg ttgtttatac atgtcttttg aatttattta gttgttattc
     7981 aaaagttcga aacgtaattt catcgatgca gtcatttttc cgacctcctt ttttattagg
     8041 ttaccacaca cgattcaaaa aaagcaatag ctactgaata gtaactgaaa accttttatt
     8101 cgaacatagt gatcttttct ggtgctaaac gaacagactc gtaaccttct tctaccgctt
     8161 ttcctattga taaaataata actggaacat aacggtcttt atccaaacca aatgcctctg
     8221 ccaactgatc tgcttcgaat ccaccaattg gatttgtttc atagccatga tcacgcgcaa
     8281 ctaacatgaa ttgcatagcc gctaagctag aatcgacttt gactacatcg ttcatttctt
     8341 ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa ttgttgatct ctgacttctt
     8401 ttggcatctt ccctgattcg taagcttggt tgtagatttc ttcgccatat tcgtaacatt
     8461 gcatatcgcc aaaaatcatg accattgcag aagaagtatc attttgtctc gtattgaaac
     8521 ggatcaaagg acgcaagatt tcttttgctt cctcgctttc agcgaccaca aagcgccatg
     8581 gtttcatatt gacagaagaa ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt
     8641 cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga tcttctacca gtcataattg
     8701 ttgaaaaatc atttttttgt tccattatta ttaacctctt tcgtttctgt tgttatattg
     8761 caaagttggg tattcaattt atctaaaagt gttagaaatt gtttcatttc tacatcgctg
     8821 aaagccgggg atagcacgga acctgtatct ttatggtcca tttcacaatg cttgattttc
     8881 ttctgggctt tttctgttag cgctacatac acttcccggt tgttctgagg atttctctga
     8941 cgcgaaacat agccatttgc ttccaatacc ttcagatgac gagtaactgc tccttgatca
     9001 atctgcaact tttcttgcaa actgctttgt agcaatggat tttcttcttt cagtctcatc
     9061 atgatctcgt atctagtaag acttataccg atattttctt caaagatctg gacgattttt
     9121 tgatcggcta atttgatttg atataaaagg tgactaatct cttctaaaga cataatttcc
     9181 tcctttctaa taattgactc gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa
     9241 aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc aatagaaaag tatagagaaa
     9301 agaaattttt tgtagaatga acggaaaaaa tgataaagaa agcacaacgc taaaaccaag
     9361 attattgatt cttatcaaac tatagaagat agctcttctg cagtagataa ttttacaccg
     9421 ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg aatattagaa attggatcag
     9481 tatgcttaaa cagtaataaa aaagttatga caagatgttg tcacaacctt ttttgagtaa
     9541 acggtgttca aaaacttgca tctgcggtaa taagttcaac caaacaaaaa acatgaaaat
     9601 ctgtttttgt ttggctgttc ttactacttg atgcagggca gctttttcac tacctctttt
     9661 taataaccat aaaatcctat tccttcatat ctccagccca tcggtgttag ccaatctctt
     9721 tccttagcac tcaaggtata gtgatgggta ccagtttttt catttggatt aaatagtcga
     9781 taaattggct tggaaccacc agaataaaaa cttagacctt cataacgcca accgattttt
     9841 gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat ggtctccact gtaaggattg
     9901 tataaacggt agacaggttg tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc
     9961 cagcctacag ttggcagata atttttttct ccggcattca atgtatataa atgttctcct
    10021 gtatgacggt tatacagacg atacatcgga gaagttgaag ttggtgctgt atcatactgt
    10081 gtcagattat aggtttcgat tacattgttc aatgtagaac cataattagg cgcagtggca
    10141 taacgacctg ttagccaagc cgtagcatct ttgtaagagt tcgtattgct tttccatgca
    10201 ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct tcaataccgt tacgttatct
    10261 tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg cattcaccgt aatccattgc
    10321 ccattcacat attccgaagt aggcatcgta acagattggc cattatagct tcctttaatc
    10381 ccaaatagat tgtaattagg ggcagaagcc aaagtactgt tcccccagcc actttcaacg
    10441 atggcttgag caatcatgac tgatgcatat aagtcattgg cacttgccaa actttgtgca
    10501 gttgaggcaa tactatcaat gaacgcttgt tgagaattag cagatgagcg agcataaaaa
    10561 gcatagccag tatagttttc gaattcagac aaatctgctt gatgggtatg tgtcaatgtt
    10621 tgcccatctg tcaattggtt cgtgatttct tctgcattct ctggattgtt ctgagcttct
    10681 gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt
    10741 gaaattgtat tttctgagac agtagctgac tgcaaagtac tttctgtatc gttttcaatt
    10801 cctgtttctg aagaactcga tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc
    10861 actgttgtgt tggcaactgc tagatttcct aaaagaataa cgctaaataa taaattcttt
    10921 gctttcatct tttttctcct ttgaattatg aaacttttcc taaataacag tgtaactaaa
    10981 aaagtaaaag caagtcaatg tccatattta aataacattt gtttcttttt aataaatttg
    11041 ctttttctgc ataaaaagac gtaaatgaag aatattcttc tccattcacg ccttaaattg
    11101 atggtcgttt gaataactat ttaacaagta attctctctg gatattatcc gttatggatt
    11161 atacttcctg tgtcgtcgga cggataatca tgttgctgac agacatccgg tctggcgttt
    11221 ctatcgcaaa tgctacagca gaagctatat cttcagatgt taatccccat tctttttgcg
    11281 cttcatgaag ttcaagagca gcctttttgt cgctgatggt ttgatataat tcagtttgaa
    11341 cagctcctgg agagatgatc gtagatttga tgttattttg ccgttgctct tgacgtaatc
    11401 cttccatgat tgcacggaca gcaaattttg ttccgcaata aacggcggaa tcaggataaa
    11461 caacatgtcc cgccacagaa tcagttgaaa tgatatgccc agatttttgt ttttccatga
    11521 ttggaagtac ggcggaaatt ccatttaaca cacccatgat gttgatatca agcatatttt
    11581 gccattcatc acggtgacct tcaactaatg gagcggttgg catgattcct gcattattgt
    11641 acaatacatc gattcgaccg aacttttcca tcgctaaatc gataactgct tggacttgtg
    11701 caaaatctct tacatctgct gtttgaatat atagctcagc ttctggtaaa gattctttta
    11761 ttgcttttag gcgatcttct cggcgtgcag ctataactag tttagcccct ttttctgcta
    11821 atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc catgatgaca atcacttttt
    11881 ctgataaatc attcattcta ttctcctcct gttttgaaaa atctcttgct tatactcact
    11941 atctcttatt tcatcttact gttcaaataa tccgttcgac aggtttgacg attttggcag
    12001 ggattcctgc aacgatggta ttgtctggga catctttcgt aacagttgca ttcgctgcaa
    12061 caatggcatt ctcgccaatc gttacgcctg gcagaatagt tgctcctgct ccgatccaag
    12121 catttttctt gatgtggatt ggctttactg acaagcctct tcgttctttt ggatcggtta
    12181 gatggttcac cgtgatgagg ttgacacgag gaccaatcaa tactgaatct tctaaacaga
    12241 tgccacctaa gtcaacgaac atcacttgac gattgataaa gacatttttc cctatactaa
    12301 tatgtttgcc gaaatctgta taaaaaggca gcagaacagt caccgtatca tctactttgt
    12361 cactaatgat attttctagc cgtttgcgga tatctgctgg ttcatggtac ccagtattca
    12421 gcgctgctaa aggctcttcg ttttccgctt ggatctgatg gatcacttca aagagcggat
    12481 ccgttactcg aatctcttta ttgacgattt gtttttcgat gaggcttgtc attttgctcc
    12541 ctccttttat ccttacttta taacggacgg cttatgatgt ctaatactta taaaacatac
    12601 ttaactattc cttttaacta tacttagtgg tatgcttttt taaaaacagg agggaaaaaa
    12661 tggatattcg tatactgacg tattttttag cagtagctag agaaaaaaat atcagccgag
    12721 cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa acaactgaaa gatttagaag
    12781 aagaacttgg tgtgacactt ttcactcgag gctcccgaga gatacagttg acggattctg
    12841 gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca
    12901 atttaacaaa tgacgcaatc atctctggag aaatctacat tggcggaggc gaaactaaag
    12961 caatctcttt catttctgat agccttcatt cgttgatcaa ggcgcatcct gatatccagt
    13021 ttcatttata tagcgggaat gcagatgata tcatagacaa actggatagc ggattacttg
    13081 attttggact cgtaatcgaa ccgacaaaca aacaaaaata ccagtcattt cgactgccag
    13141 cccaagatcg ttggggactt ttgatacatc ggaatcatcc tttagcaaag caaacagtca
    13201 tccatccgca ggaactgaaa actgttcctt tgatcatttc ccggcaaacg tcagtggaca
    13261 gtcaactagc tgaatggcta ggtttcagca tagatcagtt atcgatcgtc ggaacatata
    13321 acttattgta caatgcttct ttgatggtcg ataacgggac ttttggtgca ttagctctag
    13381 atgggatcat caatacttat gggacggaaa aagtattcat cccactcgat ccgccattac
    13441 aagcttcact gaatctcatt tggaaaaaag accagcctct ttctcctgct gctcgtaaat
    13501 ttttagatgt cctaacggag aaatacagtt aagtagagtt tttttccttc gctttcagct
    13561 ttttaacaac gaataagtta agcaaaagat ccaatgatta aataacataa gtttcttaat
    13621 ttgttccttc cttttatttc tgataattcc agtaaattac tataattata aaaaaagaat
    13681 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
    13741 ctagatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
    13801 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
    13861 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
    13921 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
    13981 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
    14041 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
    14101 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
    14161 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
    14221 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
    14281 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
    14341 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
    14401 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
    14461 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
    14521 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
    14581 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
    14641 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
    14701 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
    14761 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
    14821 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
    14881 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
    14941 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
    15001 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
    15061 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
    15121 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
    15181 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
    15241 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
    15301 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
    15361 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
    15421 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
    15481 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
    15541 gaaaacaaag caaaaacagc ttccttgatg ttagcagcag cttttgcttc attctttact
    15601 ggtgtaacag aaccacttga attctcattt atgttcgttg cttggccatt atatgtcttg
    15661 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
    15721 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
    15781 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
    15841 aactttgcta tcaaaaaatt ccatctgatg actcctggcc gcgaggaagc agatctttca
    15901 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
    15961 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
    16021 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
    16081 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
    16141 ttcgttgcag atgagatggc aaaactacat ggtggtgctg caacacgacc tgcacaaaca
    16201 aacaccgtgg ttaaaacaga aacatttgcc ggtggaacga tcgaacaaga tatttacgct
    16261 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
    16321 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
    16381 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
    16441 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
    16501 ttatatgtaa aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
    16561 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
    16621 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
    16681 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
    16741 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
    16801 gccaactccg cggtaataag tccagccaaa cgtaacatat gaagagctat tttttatttg
    16861 actcttctta ttacttgatg cagaacagct tttttacaac ctctgataaa cggtgttcaa
    16921 aaaccagttt atcggtatga agtcaaattt atgcaaaaat gtggaaagcc attttcacaa
    16981 aatttttctt catactcaaa actaatcggc tttttcacaa cctctttata cattattcct
    17041 gatccaatat ttcttttaat gctgcttcaa gagaagttaa tggttttccc aatacttttt
    17101 ctaaatcatc agaggaaata gctaactgat cctttttaat atcatgttgg atcgctaaaa
    17161 acatgtcagc tgcttcttga gggaatccgg cttcttttag attttcgaca aacgctgcat
    17221 cacttgcttc aataatttct aactttttac ctgtcgcacg ctctaatgcc ttggctaatt
    17281 cttcatagtc agttagattg ccggataatt ctaagatttc tggagagtca ctttctacta
    17341 gtacttttgc tgcagcttct gcatattcac gtttcaatgc ccaacctgtt tttccatttc
    17401 ctgcagcata aacgaattga ccagttttta aagcctgccc aatgataggt aattcattct
    17461 ctacatacca attattccgt aaaaatgtat gggaaatacc tgaatcctta atcatttttt
    17521 cagtgaattg gtgatctggc gctaatacac tgatcgagtg atcggcatct gcaaaacttg
    17581 tataagcgat ataagatacc ccagctgctt gtgctgcctt cactacattc ttatgttcgg
    17641 cttgacgatt tcctggaacg ccagagacaa aaagcaatcg atctattcct ttcaacgctt
    17701 ctttcattga gtctaaatca tcataatcac caatacgtat attaaatcca gcttctttca
    17761 gtgcttctcc tttttcttca ctacgtacta gtacatagat ttcattttgt ggaaccatct
    17821 tttttaagaa ttccagcgca taaccaccaa aacctccagt tgctcctgtt actaaataat
    17881 gcatatttgc cactccctat tctttttatt tgttaagatt tacagctgta catttataaa
    17941 ttacaccttt atcataaaga gtgtggtaag ataagtcaag caaaaaaaat gaaaggatga
    18001 caactgatga agtattctct gcaatttagt gatgcaatcc atgtacttgc ctatattgaa
    18061 atgtttcaag atacccgatc actttctagt gagatgattg ccagtagtat cgaaacaaat
    18121 gcagcaaatg tacgtaaaat catgagtcag ctcaaaaaat ccggtttgat ctttacaaaa
    18181 accggaaaac cgcagccttc ccttgccaaa agtccagatc agatttcttt actagatgtc
    18241 tatcgcagca tcgaaggtaa tacacagctt atccaagtcg atccaaaaac aaatccaaat
    18301 tgcgtcgttg gtgcgaatat ccaagaagct ttagaagaaa gctacgctcg gctgcagaaa
    18361 aaggcagaag aagaaatggc taagatcaca cttgatagtc tgatacataa aatagccgtt
    18421 ttggaaaaag aaaaaagacc agaaaacaca ggcctcgtag agagattttt ataattctct
    18481 ctactgtgcc tgcatttttc tgatcggaat cgtctacata aattctttta ttctccgggg
    18541 gacaaaagcc ttgtcatgcc cctttttcct ctctaatgct caggtcaaag cgctgaagtc
    18601 atgacgtctt gataaacggt gttcaagtag ctgaccctcg gcattagttc tgaaaaatgc
    18661 aaaatatgga aagctatttc ccatttttcc tctctaatgc tcaggtcaaa gcgctacttt
    18721 cacgacctct atattatcat ggtttattga ctaccggtat ccagatttct cccatatatt
    18781 tcccgttggt aactcccatt tcgactacag catttggacc cccaacatag gcgtaatctt
    18841 ctacttctct taaaacatgc ccaaaggccg tattcgtcaa atcatttctt aattcttcag
    18901 gcgattctgc taaagcgatt acaacaagat acgttccttt tgggaatggg atgattcggg
    18961 tagtgtttgg aacatcctga ctcgtttgaa caccgacata gtacatcatt ttcccgttat
    19021 agggttcgtt gactgtaaag aaataatgat tttcagcagc ttgtttcaat gcatctattg
    19081 ttccattacc gataactttt tgctcaaatg cttgtttctc tgcagccaaa ccgacaaaat
    19141 ccgtattgct actcttcaat tccacaccaa tacccgtcac cgtaaaatct ggtttttctt
    19201 cgatcctata ctttgccatt tctcccaccc tttctattat attaagttca tcttacataa
    19261 aattaaaggg aaatgacacg attacgctct tttttctagg gatattttta ttttttaact
    19321 atttttttgc tttcactgca atccaaatct cactgtaaac attactgaaa tcctctcccc
    19381 attttgtaaa agagatctcg ggagcttcga ctaactcata atctgaagaa ggaagccatt
    19441 ctgcatagat tttcccccaa gtatcttgta aagtttgggg aaatggccct ttattaggaa
    19501 aaatggccca agtgtgttct tctatagcaa gcatttctaa atcagcgtac ggattttctt
    19561 ttgtcgtagc aaagccaatc atgtgcatca aactgccctt ttcttccaag cgggctccat
    19621 caaatccata agaaacgttg attacttgat ttggatataa atctcctaac ttatgcatct
    19681 cttccctttg agtctccgtg atcgtctgcg ctaacttttg tatttcttga ttgactcctt
    19741 caaatttgac aggaactttt ttcgccacac ctgccacata aaactgttct ttcttttcga
    19801 tacgaaattc catcgatttt cctcctctga catcaataaa aaatgtcaag cgtggaaaag
    19861 atttttgtat gccgtatctg ctgatttctg aaggcagata tcctgaccaa tcacgaaaag
    19921 ctcttgaaaa accttcgact gtttcatatc catatctaaa cgccgtttct gtcactcttg
    19981 atccatctag gagatcgcga ttagccaaag ccaatctacg gtttttgata tagtccatta
    20041 gcgacatccc tgcaataaac gtaaagatgc gttttaattg atattcagag attcctgtat
    20101 tttcggctat tattttatag gaaagtcctt ctgtcaaatg ttcttcgatg taatcgatca
    20161 attggttcag atctttaagc atatttatct tcctccttgc ttgccttttt atcatattat
    20221 caaagaaagt caattacttg atgaatcagg aaccaattta gtcagatgta gaaaatgttg
    20281 tatggatcta aagaaaattc tcaagcagcg tttcgtaacg gataattggt attatctgcc
    20341 tatctatgtt ttacctttag aaaaataaat tttggggaag acacattcta agtaaacaaa
    20401 gcggtaaaaa tatcttttat tcccttagtt aatccgctta ctacctactg tacaaagcaa
    20461 attgttgttc aaactgctga tcagaacgct gcttggattt ttctttgcga tacatcatac
    20521 ctcttttatc aattggaaca attatttatt tctaacaaaa tcacttcatt tttgtcagat
    20581 aaataaaaaa caaaaaaagt tccatcttta aaacacgcta ttcttttact ttttctcaca
    20641 ttctctaaga aaagaaaagg agaatgaatt tttgacaatt cgagcaaaag tgattatcaa
    20701 atatgtaaaa tcagctactt ttttcttaaa cgtttcttta tactaaatat aaataagtgt
    20761 ttcatgaaag gagaactaga tgaataattg gcttgagtat tttcctgaaa acgttttgga
    20821 acgcggttac agctatcatc tgcacggttt tgtccgtcat ttgaactata caagcaagta
    20881 cttgtccgca acagtttctg gcacggaaga ttataaggta gtgatcactt gggatgaaaa
    20941 gaccaacatg acttgtgatt gtctatatgc catagaagga aaaaaatgca aacacatggc
    21001 tgctgtctta ttcgcttacg aagaacgtcc aataaaaaaa tccaactact cactttccga
    21061 actctcgtcc cttgtttcct ccgctagttc ctctcttgta cgggagcttt taacagagat
    21121 tcttatagaa catccgcaat ttatcgaacg cttcaaagtt aagatgccat ttcatgcaat
    21181 aaattattca gataaattaa caactatcat ccataaatac gatcatatta tcaagaaaaa
    21241 caaaaacagg aaaacagcga agttcatcat ggagatgcga aagttcatcc aagaagcagt
    21301 tgaatcgctc attcagcaaa atgcctatct tcccgcattc gaattgatca atgaagtgat
    21361 tgctactctc gaaacattct attgggagcc tgaggatgaa cgaacccttc ttctgataga
    21421 ggactgttat tatttatgga aagaattatt agcagaagca cctcatgcag aaaaaaggca
    21481 aatgttctct tggttcgtct gccaagtcga tcatactgac gcctcttatt caaaacgcta
    21541 ctccataaaa atcctgaaag aagactttcg ggaaaaagaa ttttctaacc aaaagaaaaa
    21601 aatagataaa aaaactaaag aaacggtaaa gaaagacgat ttcaatgaaa aatagcaagt
    21661 aaacgataac aaccatccta aatccacaag aaatacagca gaccttgctt taaaaacacg
    21721 aatcatgcaa aggatgaagt aaagaagact taacgcgtac ccaatattag tcatttgact
    21781 attaggtacg cgttttgttt tataagtcat gacaaatttc cttcgttgct gggtagattt
    21841 tccggcattg ttgatagatt ttatgatact tttctacatt ttgtaagaga ggttccactg
    21901 catctgtata ttggataaaa ttctgacaac aactttcagg tgtgtcgaac cactctaatc
    21961 tttaaagata aatattaaaa taacgattaa taatattaac agtctttatt tttcaccacc
    22021 aaaaacctat ctttgcatat actaaataga cgtatataca cagataggtt tgtcttgtga
    22081 aaaataatga ttatccttac caaaaaatgt ttgtttttct acatgttcgt acttatcaaa
    22141 aaatatgatc cttattgaaa ttactggcta tttatattcc aacgacttct tgtgttaatt
    22201 tttgttatct catagtaaat tatgtttcat tttcacttaa tttagttgtc acgtgttcgt
    22261 caattcgtaa aaacggtaaa tatataaaca cacttgcggc tataattaat atttgtaaaa
    22321 cagctgctcg ccagtctccg gctgttgcta aaaatcccga tataactggt ggcgtagtcc
    22381 aaggaatttg cactactaca tgattaatta atcccacagc agttgcaaaa tatgctactg
    22441 tcaaagaaaa aatcggtgca agcacaaagg gaataatcag actgatatta aatacaatag
    22501 gcaatccaaa aataataggt tcgcttatat tgaatatagc gggagttacc gataatttag
    22561 caaagtcctt ataatctttt ctacgactga agataaatat tgcaatcaat aaagcaatcg
    22621 tatttcccga tccacccatt accgcaaagg tatctttaaa ggccatattg ataatatgtg
    22681 gaatttgctc tttgtttgca taagctgcca tattttcttg catattctga atcaaaaacg
    22741 gatctaacaa tgaacctgat attactgctt gatggatacc aaatccaaaa aatagattag
    22801 caatagatgt aattaacaaa aatcctggta aaccagttgt aattttactt aatggctctg
    22861 taactatcgt ggtaattagc ttatttatat ccatattaaa caattgaatg attataaatg
    22921 acaataaagc aaacgaggta atcgtaataa tgattgggat taatacatta aaagacttta
    22981 aaacagcggg aggaatattt ccggatagct gaatctgtag tttcttatta ttagaaagtt
    23041 taataaataa ttctgtagcc gctaatccaa caaatatacc tacaaacatt cctgaagctc
    23101 ctgtatagga tataggtatc acacccgtca cttcaacagc tttatccgca ttttcaggag
    23161 taaacatcat ctgcataggt gttaatacaa caaatgtcga aatagcaact aataccgctg
    23221 caatatgatt tgtataattt ctgcttgcac acatatgata agatactgct gctacaacta
    23281 ataatgtagt tatgcttaat gtaccattgg caattgaagt accaatttgt tgtaacgtgg
    23341 tcaatgtact agtatcgaca atttccccca tgaatcctgt tggttctaag atcactgaat
    23401 taataagtgt cacaaatcct gctaacatca taaatggcat aaatgtagca aacgcatctc
    23461 gcaaagttct taaatggatc tgattcccca acttagtcgc aactatacca aatttttcaa
    23521 atacaatgtc cttcctgcta cttttgccca tattttttct cctttatgct tattgtaatc
    23581 gattactttt tccacccaaa taatacatca cttatcaaaa aaagtaaata cttttaatta
    23641 aatatatata tcttttttag tataaaaaaa taagctctga aaaaataatt ttcccgagct
    23701 tatttttcaa caaaaacagc ttcaaaaaca aagtcttgat ataaatgtct cgataccgaa
    23761 tactcgaaag gtttaccaga cgatagagca acaactttgt ctatctcaat cataaattca
    23821 cctggatcta tttttaatat ttttgcgtca aattcattcg cagtatctcc tttgatacgt
    23881 atgtgcgaag tctttatttc cagacccagt tcatttgtga tataagcata tacagatttc
    23941 tttaaatgtt ttggttccaa gcctggtatg actgctaatg gcatgaatgt ttgctcaatc
    24001 gagtatggtt gacaatcaat aaaacggctt cgtacaatat tatatacata gtcttttaca
    24061 ctgatactta atttatcagc tacttttttc gatggaagtt caattgagaa agtatggatt
    24121 tctgaatcta cgtgttcttc accaaccacg ctaaacaaac cttcgtttgg accaagaact
    24181 cgtgagttat caattggtgt tctgacgact tcagtcccat acccacttct acttcgcaaa
    24241 actccttcgg aaacaagtaa gtctacgcct ttctttactg ttaacttgct tgtatgataa
    24301 ataactgcca attcatctcc tgtaggaagt ttctcaccaa ttttatactc tccatttaca
    24361 atttttttct ttatatctaa gtaaatttcc atatacttcg caattttttt caatggtgac
    24421 cctccaatca aaaacatatc ttcatctata ctttaacata aataaaccga taaaatccac
    24481 atcaaaatta tacacacaat aaaaaagata tatatattta aacaaaacta tttactttaa
    24541 gttgtaagcg gtgttatcat taagtggaaa caggaggtaa aaaaattatg acaactatga
    24601 aaaagctaac ttttccagat gatttttggt ggggttccgc ttggtcagct gagcaagcag
    24661 aaggaaaagg agaaacagga aaagcagaga ctatctggga tcgctggttt aaagaacaac
    24721 cttaccggtt ttatcaacga atcgattcct ctattacaac cgatcacatc catcaatata
    24781 aagaagatat agaactaatg aaaaaaactg ggcataactc ctttcgcgtt tctatttctt
    24841 gggcacgaat gtttccaaat ggcggtaccg gaaaagtaaa tcccaaagcc atttctttct
    24901 atcgaaaatt attttccgaa atgaataata acggaatcaa agtatttgcc aacttatatc
    24961 attttgacat gcctgctact cttcaagata aaggaggatg ggaatcacgt gaagtagttg
    25021 atgcttatgt tcattacgct gaaacttgtt ttaaagaatt tggtgactta gtttgtcatt
    25081 ggtttacctt caatgaacca cttgggccta ttttaggtac ttatcttgaa gattttcatt
    25141 atccaaacct cattgacttt aaacgcggag cgcaagcagc attcttcact atacttgcac
    25201 acgcaaaagc aatacaagta tttaaagaac tagctcttcc tagtaaaata ggcgttattc
    25261 taaatttgag tcctactttt cctcgtagtc aaaatcctgc tgatgtgaaa gcagcagaaa
    25321 tcgctgattt attttatacg cggagctttt tagatcctat ggttaaaggg aatttttcta
    25381 aaaagcttat cctgttatta caagaatata atcagcttcc tgaagattat acgaaagaag
    25441 atcttgtatg tatctacgaa aataccgctc aaattcttgg actaaactat tacgagccac
    25501 gtcgcgtcaa atctcgttct tctatggtgg atacatctag tccattttta ccagagtggt
    25561 ttttcgaacc acatatcatg cctggacgac gaatgaacga ataccgggga tgggaaattt
    25621 acgaaaaagg aatttatgat ttgtgcatgg atatcaagaa ccattatgga aacatcgaag
    25681 catttatctc ggagaacgga atgggcgttg cggatgaaga acgtttcatg gatgatacag
    25741 ggcaaataat tgatgattat cggattgagt atatcaaaga tcatcttgct tacttatgga
    25801 aggcaataaa tgaaggatgt aacattaagg ggtatcatct ttggacattt attgattgct
    25861 ggtcatggat caacgcctat aaaaaccgat atgggctggt ttcactcgac cttactactc
    25921 aaaaaagaac aattaaaaaa agtggcgaat tttacaagca attaagtgat acaaatggat
    25981 ttagatacga tgtagacttg ttagttgaat aatattctaa aattccactt gaagtgaaca
    26041 cattagaaaa caagaataat gagaaatacc aataacaaat actttttctt catacttcat
    26101 ttatacttgt cagtataaga gactgtgaca aatgtagtga tcctcagaag ttaggtctgg
    26161 aaatctaact tgagaagatt tttttaaact acgtccagtc ttttttattt gtttaaaatt
    26221 gaagttgaca agtcttcatt aaaaatttag aatattcaca agtttgacga caattatgaa
    26281 aatttatgtc gtgctaaagg agttttgtta ttggatgaaa agttagatat aaaaactgcg
    26341 atcaaagaca cgttacctac cgtttttggt tatatcggta ttggacttgc atttggtatc
    26401 gttgggaaag ctgccgggtt tcatccgctg gtcgtcacgt tgatgtccct gctgatctat
    26461 gctggttctg cccaatttat cacggtcagc atgcttgcta gccatagtcc actgctctcc
    26521 atcgttctct cgacctttct agtcaattcc cgaatgattc tgatgagtat gacgattgct
    26581 ccttatttca agaaaaatcg gctgcttcaa aatctgctga ttggcacatt gctgacagat
    26641 gaaagtttcg cactgggaat gaataaattg aactatactg gacaaaagtt aaactttcgt
    26701 tggatgaata cagctaattg gatttcttat ttgacgtggg tgggttcttc tcttgttggc
    26761 gcacttttag ggaattttat tactgatccg aaaaagtttg gtttggattt cgccatcgtc
    26821 gctatgttta tcgggttact ttatcttcaa gtcatttctg atagaaacac ctctaaacga
    26881 ttacagttga tcctgattgg tctcactttg attctggtat atgtcggact gatttttatc
    26941 ccaagtaact tagtgatttt agttgtaaca ctgattgggt gcggattggg ggtgtggatc
    27001 aaacatgcct tcttttgagt ttacattgct gactatttta ggttgtactt tagcaacttg
    27061 gctttctagg atcctaccat ttgtcttact gaaaaaattc gatttgccgc aaccgttgct
    27121 tgagtattta agttttgtcc cgatcgtcat tatgtctgct ttatggttca gcagtctatt
    27181 tacccaaaat atcggacatc tgccgcagat caatctcgaa aatgctttgg cttcagttcc
    27241 tacactttta gctgctattc tttcaaaaag cttattggtg atcgtcttgg taggaattct
    27301 ttccctttcg ttgattcgct tattataaat aaaaaaacaa gagcttatgg caaattactg
    27361 tcatgcgctc ttgtttttat caaagtcaaa taagaaaaaa atcggcgtat tcttgcttat
    27421 ccgttgaacg gaccactaac aacgactttt cctaatatat gtcctgtttc tacgtctttg
    27481 gttgcttgtt tcaagttctt cgcattcatc ccatctgaat agaccttgct caatgtactg
    27541 cggataatcc cttcatttgc taaagcagca atgtgcgcta aagcttctcc ttgcgtttcg
    27601 atttcatagt tatagtctgt tttagcgaac atatactccc agtcgaagct gatagattgg
    27661 tttttccaaa cacctatatc taacggctct ttgatcccta cgatcgttcc cacatgtcca
    27721 aatggtcgga caaggtgttt gatttgatca aagtagcggg taatatcgaa taatacagcg
    27781 acatactcta cttgatcgat tcctaattca cgaaaacttt tacttaagtc gtgatgataa
    27841 tcgattggat agtctacacc tgtttttttc agccattcaa aattcttcgg acttgcagtc
    27901 gcgtagactt ctaggccagc ccaatgcgct agttgattca aaatcgaacc gacgccccca
    27961 gctccgttga tcactaagat ttttttcccg cggttggcat tttcttctgg agtcagacca
    28021 aatttttcaa ataacaattc ataagcggtc aatgaggtca acggcaaggc tgcggcttct
    28081 tcatctgaaa gattttttgg tgcaagagcg acaatacgtt cgtcaaccag ttggtattct
    28141 tgattgcttc ctgctcttgt cgttgtacct gcgtaaaaaa cgcgatcgcc gacagaaaat
    28201 ttttgcactt catcacctac agcaacaact ttcccgactc catcaaaccc taagatacgt
    28261 aaagcatttc ttatcccgtt atcttggcga agtttcgtat cgacaggatt aacagatact
    28321 gcgttgactt ttaccagaag atcccgtgaa ctgggtacag gtatctgttc tttttcatca
    28381 ataaagcttt ttggatcatc gatcgacaac ccttcataaa aaccgactac cttcattaat
    28441 tccttttctg acatacgaat tcctccttag cttcatcaag ttggagcatc catacagttt
    28501 tcatttcaat atatatagta tgctatttgt tccactttta ttcatcataa ttattctctt
    28561 acttaaagta aactatttgc acttttttgg ttaaaaaaga ggttgcgaca agacttttgt
    28621 cacaacctct tttaaacggt gttcaatcaa ctgaccctcg gtattcgctc aaaaaacgac
    28681 aaaatatgag gagctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt
    28741 cacgacctct aattcacggt gttcaagcaa gaaatcattg ttcactgaaa agcgttggat
    28801 gttctttttc aaaggtgtct aagatctctc gtacttcatc agtagatttc gtattcatca
    28861 actgaactcg caagtcattt gctcctggaa atcctttgat atagatttta aagaaacgat
    28921 gtagtcctgt gatggaacgc gggatgattt ctgaataatg atcttgcaga tctagttgca
    28981 gacgaagtag tccgatcagt tctttttctg tatgttccct cggttctttt tcaaatgcat
    29041 aaggattctt gaaaatcccc cggccaatca tgatgccatc tacgccatat ttttcggcca
    29101 attcttctcc tgtctggcga tctgggatat ctccgttgat cgtgatcagt gtttgcggag
    29161 cgatttggtc acgtaaagca atgattttag ggatgacttc ccaatgtgca tctactttac
    29221 tcatctcttt acgcgtacgc aaatggacag aaagattggc tatatcttga tgaagtaggt
    29281 gactgatcca ttcttccatc tcagacattt ccgtatagcc gatacgcgtc ttgacgctga
    29341 caggcaaacc gccagcttta gccgcttcaa tcaattgtgc cgctacttct gggcgaagga
    29401 tcaagccact gccttttcca cgttctgcta cattagggac tgggcagccc atgttgatat
    29461 cgattccttg gaagcccatt tctgccatag caatgctcat ttctctaaaa aattctggct
    29521 tgtctcccca aatatgggca accatcggct gttcatcttc tgtaaaggtc aatcttcctc
    29581 gtacactgtc ttttccatct ggatgacaga aactgtctga gtttgtaaac tcagtaaaga
    29641 agacatccgg tgctgctgca tgctttacga catggcgaaa tacaacatct gttacatctt
    29701 ccattggtgc taaaacaaaa aaaggctttg gcagctcttt ccaaaaatta gtagtcattt
    29761 atttgttact ctccattcta tcaagcagtg aagtcgcaat ctttctcaaa aacattgtca
    29821 ttatactagg aaacaaaaaa agaagcaaag tgaacagctt aaaagatgtt tctgattgag
    29881 caaaaaaaga ctgtgacaaa aatcttatca caattccttt tccggaataa atggtgttca
    29941 aaagcttgca tctgcggtaa taagtccaac caaacgaaaa ataggaggag ctatttttgt
    30001 ttggctgttc ttattacttg atgcagaaca gctttttcac aacctctcca ctaaacggtg
    30061 ttcaatcagc tgaccctcgg tattagctca acaaacgaca aaatatgagg aactattttc
    30121 ccgtttgttt ctctaatact caggtcaaaa cgctgatttc acaacctctt ttctaacttc
    30181 tcaatcctct tcctttattg atcaaatacc aagtaacggc gtacaaaaca acgatgaata
    30241 gcacaagtac gatcatcgat gttgctactg gcacatcgat tgttccaagg aatccgtaac
    30301 ggaaaccgaa gatcatataa acgatcggat tgactttcga aacagcttgc caaaatggcg
    30361 gcaacataga gatggcatag aaaacgccac ctagataagt taacggctgc aagacaaatg
    30421 taggcacgat cgatacatcg tcataagact gagcaaaaat cccgttgagc agtcctgcta
    30481 acgaaaacaa gattgccgtc atcaataatg taatgatgac catgaaccat gaatacacat
    30541 gaagtggtac aaagaacaag gaaatgatcg ttacgagaga gccgacgaga atactgcgac
    30601 ccactccgcc aatcacaaag ccccaaatga tcacatgcgt aggaacaggc gctaccaaga
    30661 tttcttcgat gtttttctgg aatttttgag agaagaagga cgaagaaacg ttggcatacg
    30721 aactagtgat agcagacatc ataatcaaac caggcacgat gaattccata tatgaaaaac
    30781 cacccatgtc accgatccga ccaccgatca tttttccgaa aataacaaag tacaaggatg
    30841 tcgtgatcac aggcggaacc agtgtttgga cccagatacg caaatagcgg ttcgtttcct
    30901 tgatagctaa actttttaat gcagtaaaat aaagattaaa catttttctc ctccgtatga
    30961 ttattttctt ctgtgatttt caaaaacagt tcttctaaac gattcgactt attcctcata
    31021 gaaagaactt tgattccttg tcttgtcagc tgatcgaaga ttccgttcac cccttgattt
    31081 cgttcaactt cgacagcgat tgtctgttca tcttcaaatg tacaagcgta tccttcaatc
    31141 acaggtttgg tctcatatgg cgctaaatca aagataaatg tttcaaattg cagtttggat
    31201 agaagctctt tcatactagt attctcgatc agttcacctg attggatgat cccgatgttg
    31261 cgacaaagca tttcagcttc ttctaaataa tgcgtcgtca aaatgatcgt tgtaccattt
    31321 tcgttcaatt ctcggagaaa ctcccacatc tcgcgtctca attcaatatc gactcctgct
    31381 gttggttcat ccaagatcag caaacgtggt tcatgcatca atgccctagc aatcatcagt
    31441 cttcgcttca ttcccccgga aagcatacgt gcacggacat ttctcttttc ccaaagattg
    31501 gactgcttca aatatttttc gctgcgtttc atcgcttctt tgcgagagac accgtagtag
    31561 cctgcttgat tcacgacgat ttgctggacc gtttcaaagg gattgaaatt gaactcttgc
    31621 gggactaatc caatctgttg ctttgctcgg actagatccg tatccagatc ataaccgaag
    31681 acattcactt ttccagatgt tttattgact aaagaagtaa tgattccgat cgttgtagac
    31741 ttcccagctc catttggtcc taatagcgca tagaaatctc cttctttcac ggaaagatcg
    31801 attcctcgca atgcttcgac cccacttcca taaacctttt tcaaattatt tatttcaagc
    31861 gcatttgcca tttatttcct atctccttat agacatgatt ctttattgta tcatggaata
    31921 cagcagatga aaaaacaact tggttccagc gaaaaatcag gttgctgggc tcaggaaaat
    31981 ctcctaatga aagacatcaa tcggacgaag tcagacaacc ttttcagaaa aaacaaatcg
    32041 aagataaagg attactattc atatgtgcaa caaaaggagc gtgagacaaa agtaaagaac
    32101 acttttgtct cacgctctaa acacgtataa acggcggaag caaaagccaa gatttttgat
    32161 ccaataaata ctttcgatca cttcgcctat cccaatacat gccactgccg cttttcatca
    32221 aataacgcgg cttccgtttt tgcggtttct actaaagtct ctgggtaatc caaaactttc
    32281 agcaaggcaa tcgcatttcg ggtccttgaa ggtccttctt ttaatttgaa atcaaaactg
    32341 attccttttc cttctgttac ttgttcttca aagtggacat tctcacaata attctttaaa
    32401 atctctgtca attcgatatc atgtgtggcg acaaatgcta aagatggata ctccgcaagc
    32461 caccgaacga ctgaagcgga agaagcaatc cgttcgatcg tatttgtccc ttttaaaatc
    32521 tcatctacga agcagtagca gcgttctttg gaagccactt ggtccaacaa acgtttgatc
    32581 gatttgattt ctgaaacaaa ataactgtcg ccttcaaata aatcatcttc gattgccatg
    32641 gaagtcaaca catgtccagg ttgcagggta aactgttctg caatcgctgt ttggatcgtc
    32701 tgtgctagaa tacagctgat ggctatactt ttgacatacg tagattttcc tgatgcattg
    32761 gaacccgtga ctaatgtatt cttctgccag ttgaccggat tcactaccgc ttcttttaac
    32821 aatggatgat agatatcttt cgctgtcaca ccgccctcag taaactctgg tcggcaagtg
    32881 atgggcatat aagtacggta attcaatatt gcagcggcta cttctaattc tcccagcaat
    32941 tcccacagct tgatggcttc agttgaatgc ttttctaatt tagtgagaac gaaatgatag
    33001 gagataaatg gcagcatgaa catgatgttg acatattcaa aaatcaactc tgcttcactc
    33061 ccactcttca tacgaaatga aaaacctaat ttagggatgt ctcttaatgg tttagtttgc
    33121 tgtttcagct cttcttgaag tggtgtcggc agttttgcta gctgattggc ggctgaaatc
    33181 gttgaaacca aataactcat gctattcagc tctgtttcta gtgtttgttt cttcactaga
    33241 taatagaccg tattgaatac taacccaccg attgccaaat agattcctag tacttgtcct
    33301 aaaagaagca aacccaaacc caccagcgga agcaagccaa gaaaaataaa taaacctacg
    33361 cgtccaatct ttttactttt tccatccgct agatattgtt ttgcaaaatt atgatctttt
    33421 tttcctaaac gagcgaattg atattggatt ttttctctca gttgaggatt ttcctgataa
    33481 aaagcaatca gtttttctaa ctgctgatct tcaccaaaat caaagctgcg taaacgttga
    33541 tacaacgctt ctgaacctac actagaatag gtactgttga ttccttcgaa tacttcgaac
    33601 atatccaggt cataccaagt aagatcatcg atttcgctat cccatgaacg gaacttcttc
    33661 tccgtgagcc atgcttcctt caagctttct tctttatcaa atctcggttg ataaggaatt
    33721 ttttcccatt tgctacgaac tgtttccttt aatttcaaac gtgaaaaaat gtctaaagca
    33781 actaataaaa taacagctgc aataataatt aaaacgataa attctctttg acccatatcc
    33841 ctctccgttc ctttatttgt tagctttagt atagcactgt tgcgctattt gaaaagaggg
    33901 taaaaaaaca cctttcaaaa taaaaggtgt ttttttcttg tatattacat atttatctct
    33961 catttatcaa aattgacaaa taatcatagg gaggaattgt tgttaattct tgtttattct
    34021 ccagtgcatt gacaactgtc ccaagggaaa ggatagcctc aggtactatt ttttcttgtt
    34081 ctgttggatt agctaagcga agaacaaatc cttgttcatg aaaataagaa ggataaatcg
    34141 atgatacaat taagtcttca ggtaattcaa tcaatgaaaa tttacgagga acatcaagtt
    34201 cattttgtaa tggccaaatc ttgttatcta acctgtgaat aaatacattc agtttctgct
    34261 tttgataaga aatagattgt tctaaccgtt tttctgcctg ttttgccact ttgaactcat
    34321 taaatcttcc ttcttctaca ttaaatccaa aagtgacttt atactcacct atctcttgag
    34381 ctagcggtgt ttccatcatg acatgccctt catttgtcgt atctcctgaa gctcgcccag
    34441 gtcgccaagc aagattaggt tttccaagtt cccctgttgt tgaaaataag gttatgatta
    34501 attgattttc tatacgttca tactctttta aaccatctgc ataaaacgta aaataatgat
    34561 cattttctgc cacagagaca ctcttatcga atatttctaa attaacaggt ttctctacca
    34621 tagtttctga ccaattcgga ggaatgacat caggggtatt ttcaataaat ccgttttgaa
    34681 tttgtgcaat tgatttttca gatttatcta aaacattaat tgctaagcgc atacgatgcg
    34741 agtaaacagt attatgaatt ttgagtgtgc cttcaacgat ttgactttct cccagactga
    34801 acgatatttc ataagatatt tcttccattt cgggtttttc agataaacga tcttttaaat
    34861 ctttaggaag ttgagctttt ccgtaaacaa ctaatgtttc ttgtaaagaa tctttatata
    34921 ctttagctgt ttctaatttt agagatagtt ctgtatctcc ttctaatggt gaataatcat
    34981 acgtatcgcc atcatttgct gaatcgatca aatgaacgaa atcaagatat tgtctatctc
    35041 caactatcaa attcaattgc ccatctttaa aagaaagttt atatttattg ttacttatct
    35101 cagttttgtc tatctcgatt gctgtttcta atttttcatt atttttctca aattcaacaa
    35161 cagtgtatcc tagtgctggc acatttacat ttatttttat gtcaagttca taataagctg
    35221 gttcatcaaa atattcgaaa cctgtagcaa tcatccgata agcatttttc cgttctggaa
    35281 aataaacttc tttttcaatg atattatagg gactaccttt gaagtgtatt ttctttgaat
    35341 cagctactac atgcacgatt ttcgatccac tataattctc agtcgttgtg ttgaaaacaa
    35401 ggacttcatt cgattttagc tttaatgcat cagccatccg ttttacaata aggttttcga
    35461 ttccgtcagc tatctcatta gcttctttga ttcgatggaa aatatcttcc gcaacattat
    35521 ctgaaacaca gccaccaata ctatcatgag cctggttttg caaaatcttt ttccataacc
    35581 gacgaagtag gcctttactg atatggatac catttctttc tgcaatcagc atgagcggct
    35641 caactcgttt tagaattttt tgttccaatt taaaattttc tattttcatt tttgttctta
    35701 ctgagccaat agaacgatga acacgagagt aaaccggctg acgaagttca cctttatatt
    35761 caggtaattc ttttttgttt ctgataactt ctacataaga aggataatct gaaataatat
    35821 tgtggaattt actgtattta ttcaacttct ctacgacttg atcaaaattt aaaatcattg
    35881 acttttgatc tacacccgaa ggtactaaaa tatctttgtt ttttccttgc atatgaagca
    35941 tttcaactgc ttcatccaac ttttcttttg caaattcagg aatatcttta attgcgtcta
    36001 aggtcatcat tccagtcata taaccaaatg gaaaattcat ggcataaaca aatttatctc
    36061 ccaatccttt ccagataaaa taaggagatg gaaccatcgt ttcaaagttt aatcctcgcc
    36121 aacacatgaa attatcgatt tctacttgat gcaaaagtgt aggcaaattc gcattgaacc
    36181 caaacgtgtc aggcaaatac cctaccatca ttggatctcc atatttaagg atcgtatcac
    36241 tgattccaat cattaagttt cttaaaattg attcagcatc cactaataag gcatctgttt
    36301 gtgcatacca cggtcccacg aatagttgtc ctgttttcat cagtcgttgg ataaccttaa
    36361 gcttttgcgg attgatctcc aaatactcat cgacgattga agtttgtcca tctaaacaaa
    36421 agtttacttt agggttcctt tccaattcat ctagaacttc agtaaagacc tgatcagaca
    36481 atacgatggc atcttcattt gtaaaatacc attctctgtc ccagtgcgtg tgttgaatta
    36541 tatgtgcatt taccatatca gattctccta ctttccttct tctactgaat ttacttgttg
    36601 ttctttttta tacttgatgg attttagtgc attgaccatt aacgctgtaa ccactccccc
    36661 aataacaatt gatactaaat ataaaggtat attcgtaaca aaaggaattg ccataaaggt
    36721 tgaaagcatt gtttcttgag taacaccaaa aaatccattt agaccacatg ctactgcagt
    36781 gcccaccacg atgcttggta ttactcgtaa aggatctttc acggcaaacg ggatcgtccc
    36841 ttcagtaatc cccacaaggc ccataatcat agctgtcttt gcattatctc gttccgattc
    36901 atcataaagt tttttgttta aaattgttgc taaaaacatt ccaaatggcg gaatagcaat
    36961 tcctaataac atggctgtac taggtccaaa gcttccgctt gaaaaagaag caaccccaaa
    37021 agcatatgcg attttattga taggtcctcc catatcaaac gccatcattc ctcctaaaat
    37081 agccgacatc aaagcagcat ttgctcctga catgccttct agccaattag tcagtcctgt
    37141 tgtcattgct tgaataggcg tagctagtac ataccataat atgattccaa caactaatgt
    37201 agtaacaaaa ggaatcagca taattgattt tagactaata acttgcatcg gtacttttac
    37261 ttttttcaat gcattagcta aatagccaca agctaatcca gcaaccattc ctccaataaa
    37321 tcccatacca agattttgac acatcatccc agtgataaaa gctggtgcta gaccgggacg
    37381 gtcagcaatt gaatatgcga tataggctga aatcatcggt acgataaact gtaatcccgt
    37441 ctgaccaatc attcgcagga ctccccagaa tgtatccgtc tggtcccaaa cacctgtgcc
    37501 accaaaaatg actgcaatag aagttagtaa ccctgctgct acgacaagcg ggatcatata
    37561 ggaaacccca ctttggaaat gatttagaat ttctcttcct tgtttcttga attccattag
    37621 taactccccc acgatatatt ttttatttgt taattaatgc aattgcttca tcaatcgtct
    37681 cttcaccatc ttttactacc tctgaggtcc ctactgttaa aatcggttta ccgtcaaagc
    37741 gacctcgttc tgaaacattt gtatctactg caaatatgac aacatctgcc tcggaaacat
    37801 ccgaaattga aagtttgttt tctatcccca tagccccctg tgtttctact ttaatatcta
    37861 accctttctt cttcgcaaac ttttctaaat tagcttttgc catataagta tgggcaatcc
    37921 ctgcgataca tgctgttact gctactattt ttgtcatatg aaattcctcc ttttaaaatg
    37981 atagagcttt taccaattct tttttatttc tcgaatcttt tattctttta acaaactcgt
    38041 catccatcaa tcttccagat aattctgcta aaatacgtaa atgattagta cctttatcag
    38101 tgtcttttat tgctaacaaa aagacgagat caactggttg atcatctaat gcgccccatt
    38161 caacagaccg ctttaacttg gctacagcca ctgttgattc aattactgct aggcttttgc
    38221 catgaggaat ggcgatattt ttcccaattc ctgtggtcat atggttttct ctgtcaaata
    38281 cgtctttttg aaattgtttg tggtcagaca caaacccatt agtctctaac aatttcgata
    38341 atttttcgac tacacttttt ttatcagatg catttaaatc tatcactata ttatttatat
    38401 tgattttttc actgatcatt tataagcctt ctttcaatat ataaactaat ttttcaaacg
    38461 acgaactcgt ttttaaattt gctaataact catgattcga agcgatttca ttgaatgttt
    38521 cataaatttt attcaattca ggttttactt tttcattaag tgcaaaaaag aaaacagaat
    38581 gaacaagtgt cccatcccaa tcaattcctt ctggattaac gtagacacag attactggct
    38641 tttttataaa atctacttcg atatgcggca tagcaaaatc attcatcgct gttgaagata
    38701 gtttttctct tttgattgct ccctctagta tcccttcttt cgcgtaattt tcttttacca
    38761 attttttggt aattatattt aaaacgttca cttgattatc ctttatttgg tgggtaaaaa
    38821 agcaaaatcg tttatctaat aaatttagaa aagcatcttc tgtttgttca tttaactgta
    38881 gatactgttt tacttttctg acatctgccc ctaacatcaa aggactaaca acaataacag
    38941 gaaaatttgt attttcaatc ggaatcgtgc ttataacaag ttcatcagtg acttttctat
    39001 cttgtagttc attgatgctt agtacatctt ctatctcaac catatctgca aaaccgttat
    39061 ttattctttg ctctaataat tttgatgttc catatccgct actacaaact aatatcactt
    39121 tcgttttgtc aggtttgtaa cgatccaaaa gtgattgaat atggagtgtt acgtaagcga
    39181 tttcatcttc attaaaatgt atacagaatc tctcttcgat ttcctctaat aaatctacac
    39241 ttatcataaa tgacctttta aaagaatatt tgattttgtc cgtataaggg ttatagatat
    39301 ttactcccaa tttgagtctt ttaactgctg cattgagatg taatactaga ttattgatca
    39361 attcttcatc aggataaaat tcatttaatt taattcttac taactcttgt agctcaacac
    39421 ccatatctaa ataggaaagc ttcgtttgat ctaagtcgtg attcatagca tttttttcaa
    39481 tcgaagtaat gtgaatgtca acataagctt gttcatctat tggcacaata attgaaaatg
    39541 ctttttcaat cattttgatt aaaataagtg tattctttga gatttcttct tcagaattat
    39601 tactacgtga taagaaattg cttgtttcaa tcctttctat cgcaatagca aggtggatag
    39661 ctaaagtttg aaattcataa tctgtaaatt tcaattgtgt cttattcatg tatcgattaa
    39721 gcaattcggc tacttttttc aatatgtcct tatttaagaa attattcgct tcaccaatga
    39781 aattgatatt caagtctaag agatctgttt tactgttaga tgctgtaaag ccaccccaat
    39841 aatagttcac aacttctgac atcaaccttc ttttactttt ttcatcagct ttgatgcgca
    39901 cgccatttcg atctgaaact aaggacatcc catgcttgtt tagtcttttt ctaacatctt
    39961 tcattgtgct ttctaccgtc gacctgctca cgtataattc gtcagcaaga ttttgaatct
    40021 ttagagaatc attagtattc aataatttag caaacacata agttagacgg tcctccggag
    40081 agtctgcgat attgatttta tgactggata ataaatttcg aagtgtttct ttttttccaa
    40141 taagcgaaac gcctttttta ggttgaacca acatttgtac atctggcatt ttttggatta
    40201 tttctttcaa aattaaaata tctttgctaa ttgttttcgt agatacatat aattgttctg
    40261 ataattcttt gtaagttgtg tgctcatttt caatcaaaaa gtatagtatt ttcatttgcc
    40321 gttcgctaaa ttcgatgccc attatcttca cctcctgaat acagcttaag tgtacaatta
    40381 ttatctctat tttcatacag aagaaagttc ttgattaatg tagaagtttc taatattctt
    40441 gattatttca aatcaataaa aaagcctgca atatttatat cacaggcttt tttctctatt
    40501 aaatatatat aagataatac ccgtggtgct agttaatttt ttcctagagg aaaatgtcta
    40561 aacatgttgg taaatcaaca aaaaaacgca tatagtagtc tcaaaactcc caagaaatga
    40621 ggactacata tgcgttcatc aaaatatact gaacattata cagatacttt tataacattc
    40681 aaggaaatta tgagaactgt ttctaacata taccacaatt gtgtaccaga taagattaaa
    40741 aaccgaagaa atactgatca actgaagcaa cgcgatacag tgattattgc ttgtgttata
    40801 tggggcataa ttaatggcta tactagccaa agagccacgt atagagcggt ttgtt
//
LOCUS       DAPBBV010000026        39014 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.026, whole genome shotgun sequence.
ACCESSION   DAPBBV010000026 DAPBBV010000000
VERSION     DAPBBV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.026"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            6..305
                     /locus_tag="RD486_001658"
     CDS             6..305
                     /locus_tag="RD486_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7663392.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="RD486_001659"
     CDS             378..1739
                     /locus_tag="RD486_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDT7663393.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="RD486_001660"
     CDS             1761..2021
                     /locus_tag="RD486_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663394.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="RD486_001661"
     CDS             2035..2787
                     /locus_tag="RD486_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDT7663395.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="RD486_001662"
     CDS             complement(2881..3486)
                     /locus_tag="RD486_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7663396.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="RD486_001663"
     CDS             complement(3539..4513)
                     /locus_tag="RD486_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HDT7663397.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="RD486_001664"
     CDS             complement(4891..5610)
                     /locus_tag="RD486_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7663398.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="RD486_001665"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="RD486_001665"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDT7663399.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="RD486_001666"
     CDS             7161..8558
                     /locus_tag="RD486_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7663400.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDFFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="RD486_001667"
     CDS             8639..9079
                     /locus_tag="RD486_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7663401.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="RD486_001668"
     CDS             9227..9553
                     /locus_tag="RD486_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7663402.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="RD486_001669"
     CDS             9554..10303
                     /locus_tag="RD486_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663403.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="RD486_001670"
     CDS             complement(10383..10838)
                     /locus_tag="RD486_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDT7663404.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="RD486_001671"
     CDS             complement(11265..11540)
                     /locus_tag="RD486_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663405.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="RD486_001672"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="RD486_001672"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDT7663406.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="RD486_001673"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="RD486_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDT7663407.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14771..17437
                     /locus_tag="RD486_001674"
     CDS             14771..17437
                     /locus_tag="RD486_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7663408.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17801..18553
                     /locus_tag="RD486_001675"
     CDS             17801..18553
                     /locus_tag="RD486_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7663409.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18575..19729)
                     /locus_tag="RD486_001676"
     CDS             complement(18575..19729)
                     /locus_tag="RD486_001676"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HDT7663410.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19914..22355
                     /locus_tag="RD486_001677"
     CDS             19914..22355
                     /locus_tag="RD486_001677"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HDT7663411.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22685..23389)
                     /locus_tag="RD486_001678"
     CDS             complement(22685..23389)
                     /locus_tag="RD486_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663412.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23576..23821)
                     /locus_tag="RD486_001679"
     CDS             complement(23576..23821)
                     /locus_tag="RD486_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663413.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23838..24689)
                     /locus_tag="RD486_001680"
     CDS             complement(23838..24689)
                     /locus_tag="RD486_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7663414.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24855..25859
                     /locus_tag="RD486_001681"
     CDS             24855..25859
                     /locus_tag="RD486_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDT7663415.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26100..26456)
                     /locus_tag="RD486_001682"
     CDS             complement(26100..26456)
                     /locus_tag="RD486_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7663416.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26824..28011
                     /gene="tuf"
                     /locus_tag="RD486_001683"
     CDS             26824..28011
                     /gene="tuf"
                     /locus_tag="RD486_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDT7663417.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28199..30790)
                     /gene="mprF"
                     /locus_tag="RD486_001684"
     CDS             complement(28199..30790)
                     /gene="mprF"
                     /locus_tag="RD486_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDT7663418.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30816..31577)
                     /locus_tag="RD486_001685"
     CDS             complement(30816..31577)
                     /locus_tag="RD486_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7663419.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31744..32376
                     /locus_tag="RD486_001686"
     CDS             31744..32376
                     /locus_tag="RD486_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HDT7663420.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTNLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            32435..33295
                     /locus_tag="RD486_001687"
     CDS             32435..33295
                     /locus_tag="RD486_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HDT7663421.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33480..35795
                     /locus_tag="RD486_001688"
     CDS             33480..35795
                     /locus_tag="RD486_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7663422.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35977..37818
                     /locus_tag="RD486_001689"
     CDS             35977..37818
                     /locus_tag="RD486_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDT7663423.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37842..38951
                     /gene="rpoD"
                     /locus_tag="RD486_001690"
     CDS             37842..38951
                     /gene="rpoD"
                     /locus_tag="RD486_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDT7663424.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
BASE COUNT        12557 a         6864 c         8087 g        11506 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaaaatta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag atttttttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcgggtttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct ttttttttca gacaggacta gggccaagat caaaaaatgg
    14761 gggatgaaat ttggaaaaca aggaacaagc acaacaagcg gtctataaag aaacgatcga
    14821 ctcgttgatg cagcaaacgc agagctcaac cgatggattg agcaccacgc aagcgaagga
    14881 aaaattagaa agagatggct tgaaccagct aaaagaaaag ccgaagaagc caacttggaa
    14941 attgttctta gaaactttca aagatgcaat ggttatcgta ttgctgattg tcgcactgat
    15001 tcagatggtc atgggtgact acatcgaatt cttagttatt tttgcagtat tgatgttgaa
    15061 ttctataatc agtgttgtcc aaacaaaaaa agcagaaggt tctttagaag cgttgaaaaa
    15121 cctttcagcg cccgatgctc gagtgattcg tgatggtaag gaaaaaacga ttccggcaaa
    15181 cgaacttgtg gtaggagata tcgtgttgtt agacgcaggc gattatgtac ctgctgatgg
    15241 acgtttacta gatgcgggat cattaaaagt agatgaaggt atgctgacag gagagtcgac
    15301 ttctgcagaa aaagaagtaa cggatatcac aagtacggta ccaatcggag atcgtacaaa
    15361 tatggtattc agtggaacga tcgtaactta cggacgcggt aaattcttag tgacttcaac
    15421 tgggaataat acggagatcg gacaagttgc tggccttttg gaatcaacaa ctgagcaagt
    15481 cactccgtta caacgaggtc tggataaatt cagtaaaaaa ctaagtttgg ctattttggc
    15541 attgtcttta ttgattttag gtatccaact gtttcgtatt tatcttggag aaggtacagg
    15601 agatatgact gcagatatcg tcagcgcagt gatgtttgcc gtagccgtag ccgtagctgc
    15661 tattccagaa gcattacagt ctatcgtaac aatcgtgtta tctttgggaa cgaataaaat
    15721 ggcaaaacgt catgccatta ttcggaagct tccagcagtt gaaacacttg gttcgacaag
    15781 tatcatctgt acagataaga ctggtacatt gacacaaaac aaaatgacag ttgttgacta
    15841 ctttttaggt aatggcgata ctggggattt cacaaatgac ccttcaaaat ggacagctga
    15901 cgaacgtcgc ttgatcgaaa tcagtgtttt agcgaatgat gcatcgatca gtgaagacgg
    15961 tactaaattg ggcgacccta cggaagtagc gtttatcgac tttagtgaaa aattaaacca
    16021 gccttatcag gaaatccgaa acaactaccc aagacaagca gaacttcctt ttgactcaga
    16081 tcgaaaatta atgtctactg gacacacaat tgataacaaa aattacttgt ttgttaaagg
    16141 cggaccagat atcgtcttcc aacgcagtaa aaaagtattg ctaaatggtg aagtcgttcc
    16201 gatgacggat gaattgatga aaaaattcca agagcaaaat gaagcttttt caacacgcgc
    16261 attacgtgta ctagcttttg cttaccgtcc acttgataat tttgatttat catttgaaga
    16321 tgaagacgat ttgatccttg ttggtttgct tgctatgatc gatcctccac gtgctgaagt
    16381 gactcaggcg gtaacagaag caagaagtgc aggaatcaaa acaatcatga ttactggtga
    16441 ccacaaaaca acagctgttg ctatcgcaaa acaaatcggg atttttgaag aaggaaacct
    16501 ggctttgacc gggacggaac tagatgaatt gacagaagat caactaaacg aagttttaga
    16561 aaaagtcact gtttatgcac gtgtttcacc tgagaataaa attcgtatcg ttcgtgcttg
    16621 gcaaaataaa ggtcatatct cagctatgac aggtgatggt gtaaatgacg caccagcatt
    16681 gaaacaagca gacatcggaa ttgctatggg aacgggtaca gatgtggcaa aagatgcagc
    16741 agcgatggta ttgacggatg ataactttgc ttctattgtc agcgcagtag aagtaggacg
    16801 taatgtgttt gataatatca agaaagctat ttcttatcta tttgcaggaa atttaggtgc
    16861 gatcattgcg atcatctttg ccttagttgc tgactggtcc aatccattta cagcattaca
    16921 actgttgttc atcaatttag tcaatgattc actgccagca attgcattag gtacagaaaa
    16981 agctgaacct gctacgatga accgcccgcc aagagatcca aattcaggaa tctttacgga
    17041 caaaacattg atttctgtaa cgtatcgtgg tgtgctgatt gggattgctg ttatctttgc
    17101 tcaatggctt ggcatgcagc attcacctga attcggtgta gccatgtcat tttcaacatt
    17161 gatttggtgt cggacattgc aaacattccc agcacgttca aacacacaaa cagctatcca
    17221 agcagggttc ttctctaaca gaagtgtctt actagctgta gttgtatgta gcgcgcttta
    17281 ctgcttaaca atgatcccag gactgaaaga agtcttctct atcccatcag catttggatt
    17341 gacagaagtc tttacatgta tgggaatcgc acttgtgaca attgttttga tggaaatcac
    17401 taaattgatc attgtacgag tacaaggaaa taaataaaac gaatcaacga ggttgtgagc
    17461 ctgccgttta attctgagtc acaaggtgca atttcaacaa acagcttctc atgtttgttg
    17521 aatattgtga cttgtgaccg aagagttggc aggagaacac cgtttaagga agaagttgta
    17581 aaatcagcat tttgagctaa tactgagggt catctgattg gacactgttt attcggaaag
    17641 agggactttg acacgacttt ggtcacagtc ccttttttta tttatgatag acggaaagcc
    17701 aatcatttta ttattcatca aaagagatag aatagataaa agaggagaat gatttattcc
    17761 gaaaagtgaa aacatataac aaaaaattag aggaaatcaa atgaatgaaa aagaatggga
    17821 tgaatttgct gaagaatatt atgaaatcca gcaagaatcg caagtaacta ttgctgaaga
    17881 tgtaaaaaat tatctgaaaa cggagaaagt cctgcctgct gaaacagcag cagacgttgc
    17941 tggaggatct ggcagatttc tttccttagc aaaagaaatt aatcgctatg atttgatcga
    18001 tttttcttca ggaatgctag aaaatgcaaa aaaagaagca gaaaaaaatg agttgccaaa
    18061 tgtttccttt atcaaacagt cgttagaaga atttatccaa tcaaatgaga catatgaaat
    18121 ggtttttaca gcagcaaatc cagcattggt acatcttatt caattagaaa aattgatgaa
    18181 aaagtcaagc aaatggtgcg tgataatcag agtagtggaa tcaatcgatg atgtttttta
    18241 tcctatcgaa aagcaactag gaatgataga agaagatcct aatacatcgc cagttgtaat
    18301 ggatcaattt gaaacatact taattgatga aggattcaaa gtgaagaaaa aagattttac
    18361 ttattttaca caggaatcaa ttactgaaga attgatgaag ctatactatg acgcgtacgc
    18421 aaaagatcct gttgtgacca ggtacattcg caaactattc agtgaaaaac gagaaatcct
    18481 tagtacgact aagctgacct atagactgct cctttggtcc gcagataaaa aaagaacctt
    18541 tcacgactcg tgaagggttc tttttatgat tttattatat tttgtagtaa cgaatatcat
    18601 tttcgatctt tgtaatcgaa aaaggtacat ctgaagtata ttctgcacat tctccgtgtt
    18661 caggaagcgt ctcactgaaa atcgtttcat attcgtcaac agtgatccgt gttcgagaat
    18721 ctagcatctc ttgatgagat tgtgcgaaga gatattcttg atagttttct tccagataac
    18781 ctgtaaaaaa ttcacttact gcaccagaac cgtagctgaa tagaccgatg cgatctcctg
    18841 gctgtagtga tttcgaattt tccagtagag aagttagccc caggtataat gaaccagtgt
    18901 aaagattacc gattcgtcgg ctgtaacgga tgctttcttc atagcgagcc ataagacgtt
    18961 cctgattttc ttcgtctgtt tggtctaata cgctttgcaa tgcctttttt cccatcttag
    19021 tatacggaat atggaaagca atcgcctgat aatcttcgag tcctcgaccc gacaattctt
    19081 tatgtcgatt ccaaactttt tggaatgatt cgatatacgt agaattagat aaaggaccat
    19141 caacaacagg aaattcgcta taatctggac gccagaaatc atagatatct tctgtcagaa
    19201 atacgctgtc gtcttcaatc gataaaatac gcgggttttg agtgatcatc atcgcaacag
    19261 caccgacacc ttgcgtcact tcaccaccgc ttgccaagcc gtaacgagca atatcacttg
    19321 ctatgactag tacttttcgt tctggatgat ttttgacata ttctttcgcc atgtgcaaag
    19381 ctgcggtgcc accgtagcaa gcctctttta cttcaaaaga acgagcaaaa gattggattt
    19441 tcagtaaatg gtggataatt accgcactcg cttttgaatg atcaatcccg gattctgttc
    19501 cgacgatgac catgtcgatt agctcacggt ctttttctgt tacgattttg ctggcagcat
    19561 ttgctcctag tgtaatgatg tcttcatttg cacgattgac tgccatttgg tcttgaccaa
    19621 tccctatatg gtattttgca ggatcatccc cacggctttc tgccaactct gtcatatcta
    19681 aatataaatt aggaataaaa aaggaaagac gatcaatccc tattttcatt tcaacacctc
    19741 tttacttatg ataaaaaact tactttacta aggtatcata aaaagattaa aagaaatata
    19801 aaaaagagaa tatttaagga ttgttaaaat ttaatcttag aaaaaaataa ctggaacaag
    19861 agctatttgt ttttacagca aagaatggta tatttttgta ggaggtggct tacttgaaag
    19921 aagtcgttat gatagatgct gcaagaacgc cgataggaaa gtatcgcgga agtttaagtc
    19981 catttactgc agttgaatta ggcacacttg tgactaaagg attattagat aaaacaaaac
    20041 tgaaaaaaga taaaatcgat caagtaatat ttggaaatgt cctgcaagct ggtaatggtc
    20101 aaaatgttgc cagacagatt gctttgaaca gcggtctccc tgtagatgtc ccagcaatga
    20161 cgatcaatga agtttgcgga tctggtatga aagcagtgat cttagcacgc cagctgatcc
    20221 aattaggtga agcagaactt gtgatagccg gcggaacaga gagtatgtct caagcaccta
    20281 tgctgaaaca gtatcagtca gaaacaaatg aatatggtga accaatttcc agtatggtca
    20341 acgacggatt gactgacgca ttttcaaatg cacatatggg attaaccgca gagaatgttg
    20401 caacacaatt ttctgtgagc agagaagagc aggatcgcta tgccttgtcg tcccagttga
    20461 aagcagcaca tgctgtcgaa gccggtgtat tttctgagga gatcatccca gtcaagattt
    20521 ctgatgaaga cgtgttatct gaggatgaag cagttcgtgg aaatagtaca ttggaaaaac
    20581 tgggcacgtt acgtacagta ttctcagaag aaggaactgt aacagcagga aatgcttccc
    20641 cgttgaatga cggtgcctct gtggtgatcc ttgcatccaa agaatacgca gaaaataata
    20701 atctgcctta tttagcaacc atcaaagaag tagcggaggt cggtattgac ccaagtatca
    20761 tgggaatcgc tccaatcaaa gccattcaaa aattgacaga tagatcagga atgaatttat
    20821 caacaatcga tctttttgag atcaatgaag catttgcagc ttcttctatc gtagttagcc
    20881 aagaactgca gttagatgaa gaaaaggtca atatatatgg aggagcaatc gcattaggcc
    20941 atccaattgg tgcaagcggt gcacgtatct tgactacatt agcttacgga ttgcttcgtg
    21001 aacagaagag atacggtatt gcttcattat gtattggtgg aggtttaggc ttggcagtct
    21061 tgttagaagc gaatatggag caaacacata aggatgtgca aaaaaaaaag ttttatcagc
    21121 ttacgccatc tgaacggcgc agtcaattaa tagaaaaaaa tgtattgaca caagaaactg
    21181 cgttgatttt tcaggaacaa acactttctg aagagctctc cgatcacatg atcgaaaacc
    21241 aagtgagtga agtggaaatc ccaatgggga tcgcgcagaa ttttcaaatc aatggcaaga
    21301 aaaaatggat tccgatggca acagaggaac catctgtcat tgcagctgca agtaatggtg
    21361 caaaaatctg tggaaatatc tgcgcagaaa cacctcagcg gctgatgcga gggcaaatcg
    21421 ttctatcagg aaaatcggag tatcaagcag tgatcaatgc agttaatcat cgaaaagaag
    21481 agctgattct ttgtgcaaat gaaagttatc cttcaatcgt gaaacgcggg ggcggtgttc
    21541 aagatatctc tactcgggaa ttcatgggga gtttccatgc atacttatct attgattttt
    21601 tagtggatgt aaaagatgca atgggcgcta acatgatcaa ctcgattctt gagagtgtgg
    21661 caaacaagtt acgggagtgg ttccctgaag aagagattct attcagtatt ttaagtaatt
    21721 ttgctacaga atcattggct tctgcctgtt gtgaaatccc attcgaacgc ttagggagaa
    21781 acaaagaaat cggtgaacaa attgccaaaa aaatccaaca ggcaggggaa tatgcgaagc
    21841 ttgaccctta ccgtgcagca acgcacaaca aagggatcat gaatggtata gaagctgtag
    21901 tggcagctac aggaaatgat acacgtgcgg ttagcgcttc gatccacgcc tacgcggcaa
    21961 gaaatggatt ataccaagga ttaacagact ggcagatcaa aggggataaa ctagttggaa
    22021 aactaacggt gcctttggct gttgccacag taggcggagc ttccaatatc ctgccaaaag
    22081 caaaagcatc tttagctatg ttagatattg attcagccaa ggaactagca caagtaattg
    22141 ctgcagtagg gttagctcaa aacctggctg ctttgcgtgc attagttaca gaaggaatcc
    22201 aaaaaggcca catgggactt caagctcgtt cattagcgat ctcaattggg gctattggtg
    22261 aggaaatcga gcaagttgcg aaaaaattac gtgaagcaga aaagatgaac cagcagacag
    22321 ctatacaaat attggaaaaa atccgggaaa aataaaaaag caatatcttt agaagaataa
    22381 agcaagattt acagttattt tatttactgc agatcttgct tttttctcta tcagaaaata
    22441 tgtttattat tagaattttt tatagttaag gttaggcatc ttaagaaatc aggcaactcc
    22501 aagatatctt caggtagaag agaagtcgcc taacattgta ggatcatagg tgatttgttg
    22561 gacaggtcaa gctgatattt gagcctgatg ttagaaggaa tttcttttta cttgctgtag
    22621 aaattattat atgactaaaa aggctgggat tttaaatccc agccttttat gacaaataga
    22681 atttttatcg atcagtaatc gctgtcgctg caaattgttc gatcaaagga atcaaagtca
    22741 atttgacttt gtatttccgt tcgagtgctt tttcgataac gaactcattt tcagtagtca
    22801 tagaaatagt tgctaattta cgaggttcat cagcattttt ttcattaata actacttcat
    22861 gttcattttg ttctgtgtaa aatttaggat actcagcaac ggcttttgaa aaatcagcaa
    22921 aacttaaagc ggcattcgta tcagttgagc gtgtattttc agttgtgtcc gcttttggtt
    22981 tttccgtttt ttcttctggc acactgactg tttcttctgt aactggtgtc gcaacagctt
    23041 gcgcagttgg ttcatcgttt ttcaatcgtt gatcattcca gtaagacacg atttcaataa
    23101 gaagattgtc acggaatcgt tcgaaaatcc cgttttctcc tgaacgaatt ctctttaata
    23161 cagtattgaa gttgtcatcg attggcacgt tgatccgtgt atcttcattt gttttcccag
    23221 ctaatccgat cgttaagatt tgacggtttt tgggatcaag catgacttgt aacggcaaac
    23281 cataacgtcg caagctctct tcttctagag aacggaataa ttgtcctctt acaccatcca
    23341 atgaaggacg gaattgattt aataattttt gtttctgttt tttcttcata tgttctctcc
    23401 ttcgctcata ccctttcgat tataagaaaa aaacagccaa atgaaaagga gtaatgcaaa
    23461 aaaacttgcg tatacgcaaa ttacaacaga aaaatttgcg tattttcccg ttttttgaaa
    23521 gaaaaataaa aaatggaacg gattatgtat atatacataa tccgttccat tctttctatt
    23581 ttttcggtat caaggcaaaa acaggtagtt caggtgaata aatgacttca tgttcgtgcc
    23641 agggtttgac cattagcgaa tgatcgaacc gttttttcag ttcttcgatg atttgatcat
    23701 gtgtccagtt tcttgcagga aaatgttgga ttttctctgc atcgatcaaa aagacaaaat
    23761 cggaatgaaa agtctgggta acttcttccg agagagaatt caagcgttcg attggatcca
    23821 taaaatcacc tttcgactta aaattgggta gtatctgggt cttttgcttt gccgactaca
    23881 ccatctaact gatcgatttg tttcatttct tcttctgtta attcaaaatc aaataattca
    23941 gtattttctt tgattctgct tggtgtcact gacttaggaa gaggaaggaa ttcgtgttgc
    24001 agcgaccaac gcaaagcaac ttgtgcaatc gtcttgtcat gtgcttcagc gatttgtttc
    24061 atttcaggca catcgaagat tttaccagtg cctaatggac tatatgcttc gaggatcata
    24121 tcatgttttt ttgcatactc aactacagtt gtctgtaatt cgcctggtgc aaggaaaact
    24181 tgattgacca tcggcataat ttttgctgtt tttgctagtg tatctagatg gtggggtaag
    24241 aaattgctca caccgattgc tttgatttta cctgcttcat acagttcttc aaatgctcgc
    24301 catgtatctg catttgcttg ttcccaatta tcacgaaaag caacagggtt tggccagtgg
    24361 atcaaaaaca gatctaaata atctgtttgg agcttcttca atgattcttc aaaagaagac
    24421 atcacaagtt catagctgtg gtttgcattc cataattttg ttgtcaagaa tatctcttct
    24481 ctaggaattc cactttcctt aatcgcttgg ccgacgcttt cttcattctt gtatccttgg
    24541 gcagtatcga tatggcgata acctgcagcc agcgcttctt taacagagga aacagcgaca
    24601 tccccatcag gtgtttgcca tgtgccgaat cctactaccg ggatttcgta accatttgat
    24661 agacgataag tgcttgttaa tgaattcata ctttcagctc cttttttatt cgttcaacta
    24721 taagtgtagc gcatttttcg aaaaaaagaa tccattttgt ttctactctt gaaatttttg
    24781 tttaaaagaa aatgattttg attctggtat ttttgatttt ttttccgtaa actaagacag
    24841 aagggaatga gaaaatggat atctatttaa aaaaagcaat tctgcatatt attgacagag
    24901 aaactggttc tccagtcttt tcacaaaaag agctggatct gacaaaagaa tatattcgtg
    24961 attttcttca aaagaagatc caaaaaatct cttctgctca aacaaaaact ggacaactag
    25021 cagaagaaag catgatcgtt gaatcactta aaatcgctca agaaaatttt gtggaagcaa
    25081 gtgaagcaat cgttcagcgg tggttcgata tctaccaaga aagtgaagaa gcacctagtg
    25141 cagatgtatt tgttgtcttg tatgaattag atacagtgat gtacttatct ttattgaaag
    25201 tcaattatcg tgaggcttac actcactttg ttgaagcaga cgaagcaggg atcgacaacc
    25261 gcttgatttt gaatcgagca attctagggg cgaaaacaca aaaagcagat gaagcattcg
    25321 ctgtgaattt gactgattgg acctacgaat taattgaaaa aaaatatgag ttttctggca
    25381 aaaaagagct ttatttttct ggaagagtga tcgaaagtgt tcctgcacct tctttagaag
    25441 aaaatgtaaa agtgatccaa aaagtagcca agcatcttgg aaaaaaattt gagacagaag
    25501 aatttgatat catggctgat ttgaaagaag ctgtctatga tacgatagaa gaaaaaggtc
    25561 ggttggatca tgagatgatt gcggaaaaag tcttcaagga aaacatcacg gcaaaaatgg
    25621 cttttaaaga agaagtacaa gagcaaggat ttgtcccaga agcacctcct gtaaaagaag
    25681 tacaagaaat ttctgagaaa aaatttggaa aacaaaaatt caagctatca aacgggatcg
    25741 aactgatcgt accagtagat gtatatcgca acccagattt gattgaattt gtgaataatc
    25801 cggatggtac gatatccgtg atgatcaaaa atgtggatga agtattgaat cgtttataaa
    25861 aatgactaga atattaggtg ttcaagtacc agtgatcagt taaatgaatt gtgtcaagag
    25921 aaggatcgga aaagacgaat ataacaaaaa aagagcgtga gacaaaagta aagaacactt
    25981 ttgtctcacg ctctaaacac gtataaacgg cggaagcaga agcaactcct tcttatttct
    26041 tggagttaaa cgcttctgtc ccagcctctt tttatctaat aaaattttaa gaccatttac
    26101 taattatcga ttttttctgc cgcattttta ggcacttcag aagcctttat ttcttcccag
    26161 cttaatacac ctttacgagg attgactttg agtttaagat acgcattcat ctttaatgga
    26221 tgttctcttt cttcgcgaag cgtcacctgt tttttttcac catctttatt ataagccgct
    26281 tgcttgtagg tataagtcgt gaatttctct ccgttatctg cttgggtagc tgacatttcg
    26341 ccattcgtcg tgatttttgt ataataagct tcgccgccgt aaaaataatg ataagctgca
    26401 aaacttccgc cgagaaatat gcctaaaacg acaagtacgc caattaattt tttcatgtac
    26461 ttcacctctt tccttattat taacgaaata gaagatttcg tctattgaaa gttgttggca
    26521 acagctgaat tttaaacttt tcctcatttt gttcttattg cttcaaaaga aagttaagga
    26581 ctatcttgaa gtttttctca aaaaacacat ttttttattt ataaaaggta cttttttcgc
    26641 gtataagaca gacgagtgct cttagttgac tttgaccaat attgacgtat aataagctta
    26701 gttcgaatct tacaaaaagt aagtcggacg tattcttttt gatttagtca aaaaaagact
    26761 ataataaaaa ggtgagagct gaaatttttc agtgatctat attatttagg aggtttgtaa
    26821 attatggcaa aagaacatta tgacagaagt aaaccacacg ttaacattgg tacgattgga
    26881 cacgttgacc atgggaaaac tactttaact gctgcgatca ctacagtatt aggcaaaaaa
    26941 ggcctagcaa atcctcaaga ctatgctagt attgatgcag ctccagaaga acgtgaacgt
    27001 gggattacga tcaataccgc acacgtagaa tatgaaacag aaaaacgcca ctacgcgcat
    27061 attgatgcac caggacacgc ggactatgtg aaaaacatga ttacaggggc agcacaaatg
    27121 gatggtgcaa tcttagttgt ttctgcaact gacggtccga tgcctcaaac acgtgaacac
    27181 attttattgt cacgccaagt tggtgtaaaa tacctgattg ttttcttgaa caaagttgat
    27241 ttagtcgatg atgaagaatt gatcgatttg gtagaaatgg aagttcgcga gttattgagc
    27301 gaatatggtt tcccaggcga tgacactcct gtgatcaaag gttccgcatt aaaagcattg
    27361 caaggcgatc cagatgctga agctgctatt atggaattga tggatacagt agatgaatat
    27421 atcccaacac cagaacgtga tacagataaa ccattactat tgccagtgga agacgtcttc
    27481 tcaattacag gtcgaggaac tgttgcctca ggtcgtattg atcgtggtgc tgttcgtgtc
    27541 ggtgatgagg tagagatcgt agggatcaaa cctgaaacac aaaaagcagt tgtaacaggt
    27601 gtagaaatgt tccgtaaaac gttagattac ggggaagctg gggataacgt aggcgtgttg
    27661 ttacggggga tccaacgtga cgatatcgaa cgtggacaag tacttgctaa accaggttcc
    27721 attactccac atacaaaatt caaagcagaa gtgtacgtgt tgacaaaaga agaaggtgga
    27781 cgtcatactc cattcttcaa caactatcgt ccacagttct acttccgcac aactgatgtt
    27841 acaggaacaa tcacattgcc agaagataca gaaatggtca tgcctggtga caacgtgacg
    27901 attgatgttg acttgatcca tccaatcgct gttgaaaacg gaacgacatt ctcaattcgt
    27961 gaaggcggac ggacagtagg ttcaggtatc gttacagaga tcgaagcata agaaacgcga
    28021 ctcgaatatt ttggtaatga aaaatgttta aaataaaaga gcggtccaaa caggatttct
    28081 gtttggaccg ctctttgttc ttcaattgta taagaagaga ttgtagaagc atgaactttc
    28141 gttttacttc agtctctttt attcatcatg agagtgttca tctatcggta tgcagttttt
    28201 aatactttct tcgtatccat tttttcaaac cacttattct accttgtgtc tgctcaactg
    28261 gcgcattatc aataatcagc aaagcaatca taacatatgc aatccaacta tctctagaat
    28321 atagagtata acgtgagacc cagtttgtag cgtacttgct tttatattct cttaatccat
    28381 ggaaagaata aaaatgagaa ccaaactcgt aaaccaagta tgcaatcctt tcctgtaaaa
    28441 aactctttct ggaagttccg acatttgaaa gaggggccat ccctaaattg aaccattgga
    28501 tatgttcttc tttcatatag gcaaacaaat gcaagaacaa gaaatccata ctgccagaag
    28561 gtgctttttt agaatcatat cgcatcagat caatcgttcc tactttattg ttcgtgtaag
    28621 taggcatgat cgttgcaaaa gcgacaattt cttcttgggt atttttgaca actgcaatag
    28681 gcgctctttg tagataatct tcagagaaaa agcctaaaga aaaccctttt tcctttcgtg
    28741 aacccaacca attatcagag atatttttga aagtactcat ttgctcagta gaaaatggtg
    28801 gttgtaagac atcaaatgta aatccttctc gttcgatccg attcaagaca gcacgagtgc
    28861 ccttcatttt tttccctgaa gttgtaaaac tattcaggtc tacataagct tcttccccca
    28921 tcttaatgaa atcgtagccg aattcatgca aaatcataac aatctcttcg cttgtttcgt
    28981 agaaaactgg taaatagcat agtcgatctg tttcttcgat aaaagcttcg attgcttctg
    29041 gaaaatcttc tttcttacca gaaggatcac ccattacaat acatttatta ttgaagcaag
    29101 cgaattggag aagaacagtt ggttcaccgt ctttttcata ggcaaacatc cgcttatctt
    29161 ttaagaagat caattgacta tcggagtttc ctccataagt tgtaaggatc ttcagggcct
    29221 tttcttcatt aaaggcttcg ccaatctgtt tcttttctcc ttgaaggaaa tgaacaaata
    29281 gaacgatcat gaaactaaca gcgatgatgg ccaacaatcc cgaaaaccaa atcttttcag
    29341 aaggaaataa gaaaaaggaa ataaaatggt gacgccgatg agggaaatct ggcagattgt
    29401 ataccccaat aacgatgtaa agcaaggaca gtgcaccaat aatgattcca tcgatcgtac
    29461 gccactccca tgaatagatc aattgttccc gaaataattc gtttttagaa gcaagaatga
    29521 tcagaagcag aatagacaag aaaaccaccg gtgtgaaact aaaatcactt aataaaacat
    29581 aaagtaaagc tagaacaatc aagaagattg taggcaaata tgctcgtttc acacgtgctg
    29641 cgatccctct gcccataatg attaaaagaa atcccaatag tatactagga aattggataa
    29701 taaaatgaaa tttcaatggg ttcaaactat gaagccagcg aaactctgta aaagcttgcg
    29761 ggatagtggc agaaagtact agcatgattc cagaaaagta taataagaca accacgattt
    29821 tatgcgcaat ttctgttgct aattgtttag ggataccaga ataacgctga tcaaaagtgg
    29881 aaccgatatt tttgaagaaa aagacgattc caatcaaaaa cggaatgatg tagtagaaca
    29941 ggcgatagag caagatccac acaacgacta tttctcttgg cacaccaata gcggacaacc
    30001 cgataatcat cattacatcg aaactcccaa tttctcctgg aatcatagac acgattccta
    30061 tcactgaagc agcaatgaat aatggaattg tttgccacag atcaatccgg atttccatta
    30121 aataaccaac agaaaggaaa ctaaacagga caccggtcca ttccaacaat gaaactagca
    30181 atagctgtcc ttgagtttta agtgaggtac caccaaggaa tcctttcttt ttgaaagtag
    30241 taaataaaaa gacgacagga aaatatagac cgccgccgat caaccatatc caatattgct
    30301 tcaaaaaagg agcaactggc gtgaagacta caagtaaaaa agaaagcaga ctgtaaatag
    30361 aaagtccagc catcaaaaac aagaaaactt tcgataatgc ttggatcacg tttctgctct
    30421 ctttcttttg tccatatagt tcagagcgaa gccccacact aacaaacccg ccgaaaccgg
    30481 caatattgtt gatcgtattg atcagccagc ttgtctcaaa caggtaacga ggattctgct
    30541 tttgttcaag catccgattc aaaataatat cataaccaac cataggtaac acagagataa
    30601 gaccaatcaa tagcattagt ccgcttttcc atacaggtat agtggcaaac gtttctccta
    30661 attgctggat agatagagtt ttaccgatgg acatcaattc accgacaata atgacaatga
    30721 cagaaatcaa aaagattgtt ttgaacagtc ctaggtggtt tttcagccat tgtatggtat
    30781 tttttaacaa ataaatcacc ttctattcct aatagttatg tttcagaaag aaattgaaga
    30841 acttctcgat tgaagcgttc aggatctttt ctagctaatt catgtccttg ttctttcaca
    30901 agcacaaagg aagcttttgg tatagtttta gctatataca aagaatgttt tagcttgatt
    30961 acatcttttt ttcccacgat gatcaaagtg ggggagttga ttttttttaa atcattttct
    31021 gtaagcccga tgtcatgcag caaaagtttg ataactaaaa gatttttgcg aagacttggg
    31081 cgaaataaag agagtaacca tacccatgca taatgaatat tactgatgac tctggcagaa
    31141 aaacgaacgc ctttaacaag cgtgtttcca gaatttaaaa tcaatcgatg aactttttta
    31201 gggaagctgc tggcaaatac cagtgctaga tttgctccat cactaaatcc aagaaaatct
    31261 gcctgatcga ttttttccag caacatgatc gtattcagat cctcggccat taactgaaaa
    31321 ttcaacatag atgcttcgtt tgtcgaacga ccatgtcctc ggctatctac tagatacacg
    31381 gtatagtagc gttcgagtac agggacctgt tctgaaaaaa agcggccgct gccgtcattg
    31441 ccatgcagta aaaagagagg gaagccttga ccgctctttt catagtaaat ttcgctccca
    31501 tctggcattt ttgcatattt cttttctttt ttcacataat cacctactgt gtaaagtata
    31561 acgattatat cagtcattgg gcaattgttt ttactgaaaa acaacgatca ttttcgtaag
    31621 atgtcaaaaa atacaggaaa attcattttt tcttaaggcg tacacagaaa tcaaggaaga
    31681 aatagccaag aagataaaga aatagtaaga taaaaaaaga tgtcaaaata actaggtgat
    31741 gaaatgaagc gaaaacgatt atctattatc cgtattcttt tttacatgat cattctgacg
    31801 gttattggtg cggtgttgtt tttaggagga agaacttatc gttcggtaaa acgagtggaa
    31861 agctatcaaa tagaaataac aacagctgca aaaaattatc atatggaaaa ctacgagaat
    31921 ttgatcaagg cgataatatt gaccgaatca aaaggaaaag ggacaaatct catgcagagc
    31981 tcggaaagtc tgcatggaga agctgagatc attgataatc cagctgacag tattgatcaa
    32041 ggtgtcaaat atttggcgga aatgatagta gaagcaaaga aacaaggatg cgatttatgg
    32101 acagctgtcc aagcatataa ttttgggaaa gattatattg cctatgtaaa aaatcatggc
    32161 ggagaaaaca cagtagaatt agcagaagcg tattctaaag atgtgctgag cccactttta
    32221 ggaaatgagg aagggaaaca ataccgatat tggcggatcc agtccttgct ttacaatggc
    32281 ggctatctct atcataatgg aggtaacatg ttttatcctg atattgtcaa aatgaatgaa
    32341 aaaataatag agacctatga aaaagtcttt aagtaaaata gcaggaaatg ttcaatcatg
    32401 aataaaatta aatgaaagaa ggagtgcgca aatagtggaa aaaaggcaaa aaatggaaaa
    32461 tcaagaagtg gggtacacaa ccaaagactg gatgttacgg tttgtgaagg gaatgtttat
    32521 cggttcagga tttatcttgc caggagtcag cggtggtgca ttagcagctg tctttggcat
    32581 gtatgagcgg ctgatttctt ttttagccca ccttacaaaa aatttcaaag aaaatgtttt
    32641 gttttttctg cctgttggtc taggcggagt gacaggcatc tttctacttt cttttttagt
    32701 cagtttttta ttaggtgcgt atgaaacaac gatattatgg ttttttgtcg gatgtatcgc
    32761 tggaactgtt cctgcgttat ggaaagaagc agggaaaaaa ggaagagata cttctgatgt
    32821 gatcatcatg gttgttactt ttgttctggc ttatttgttt ttattatacg gcgctcaatt
    32881 atttgacggg caagtcgatc agaattttgg aacatggctg attgccggcg gattgattgg
    32941 tttgggtatg atcgtcccag gattgagccc ttctaatttt ttggtgtata tgggattgta
    33001 taaagcgatg gctgacggat ttaaagaagt acgacttgaa gtgattgtgc cgatcggaat
    33061 tggtgggatt ctttgtgttc ttggattgtc aaaaatcatg gattacattt tctcaaaggc
    33121 atatagcaag ctattccatt tcattttagg tgtagttttt gcttcaacga ttatgatcat
    33181 tcctaccgat tacgcgggat tgggagttgc tggggtacta gcttgtcctg ttctttttat
    33241 agccggtaca gcactaggtt ggtggatgag ccgtttggag gaacaatata agtaaagata
    33301 gattgataat aaaaacagca cacgggtgat tcaaacaaaa aggttggcat cttttttgta
    33361 aaatcattcg tgtgtttttc tataaatttt ataaaaacaa gttgttttta atcttggaac
    33421 acgctagact taaacacgtg attatttttg aaagttggcg gaaaatggag aaaaagaaaa
    33481 tgaatggact tacacagcaa gaggtagttc agaaaatggc ttctggccag caaaatgact
    33541 accaggaaga tgcatcaaaa agtacaaaac aaatattcag cgataatata ttgacgttat
    33601 tcaattttct gaactttggt attgggattt gtctgttatt tgtaggtgcg tattccaaca
    33661 tggcgtattt agcaattatt gtcgtcaata tcgttattgg aatttatcaa gaaatacatg
    33721 caagaaatct tgtacggaaa ttatcgattg tttcccaatc agaagtacta gtgatccggg
    33781 acggtaaaga acaatcgatt tctactaaag agctggtatt aggagatttg gtaaaaatcg
    33841 gagcaggaga acagatacca gccgatttac aggttatatc tggacgggca gaagcaaatg
    33901 aagctctttt gacaggcgaa tctgatttga ttgtcaaaga aactggagct gaattgcttt
    33961 ctggaagctt tttgacaagc ggttctgtca tggctgaagt tatccgagta ggtgcagata
    34021 attatgctgt ccgcttgact agcgaggcaa agactcacaa agctattcgt tctgaacttg
    34081 tagattcgat tcgcaaagta tccaaattca ctagtttcgt gattattcct ttggggatca
    34141 tactattttt ggaagcactg ttcatccgcg atgcttctat caaaatttct gttattgcat
    34201 ctgcagcagc tttgttaggc atgcttccaa agggtttggt attgctaata agtattgcat
    34261 taacgacagg ggtaaccaaa ctggcaaaaa aacgaatcct tgttcaagac atgtattcaa
    34321 ttgaaacgct ggcccatgtc gatacattat gcttggataa aacagggacc attactgaag
    34381 ggaaaatgag tatccagcgg gtagaagcac tacatccgct gtacgagaaa gccatcccag
    34441 aaattatggg gacgtatctg gcagaaagca gtgataacaa catcactatg cgggctatga
    34501 gagattattt tgagctttct aatcggtatg atgtgacaaa caaagtcgca ttttcttctg
    34561 atcgcaaatg gggcgcgatg gaatttccag aactgggagt cgtgtacgta ggagcgcctg
    34621 aacgtttggt ggaagaagat cggcttccgg acagtctaaa aacagcccaa gcgaatggct
    34681 atcgcgtact tatgttgggg atcgctccaa atcagcaatt gaacgaagaa aaaccagcat
    34741 ttgttgagcc ggttgctctg tttgaaatcg atgatccaat ccgaaaaaac gctcaagaaa
    34801 cactagctta tcttcatgag gaaggtgtgg atctgaaagt gatttctgga gacaatcctt
    34861 ttactgtctc caatatcgct agacgtgcag gattaccgaa ttatgatgcg tatgtcgatc
    34921 tttctcaaat tactgaagaa atggaagtgc gagaagctgc tcatcgctat acggtttttg
    34981 gacgagtgag tccgcagcaa aagaaattgc tggtaaatga attgaaagaa agcggcagaa
    35041 cggttgcaat gacaggcgac ggtgtgaatg atgttttggc gttaagagaa gcagattgca
    35101 gcattgctat ggcagaaggt gatggagcaa cacgtcagat tgcgaatctg gtattgttgg
    35161 actctgattt tactacattg ccagaagtcc tgtttgaagg acgccgagtg gtcaacaatg
    35221 tgacgaaagt ctcaggcatc ttttttatca aaacgattta ttcatttatt ttatcgatta
    35281 tatgtgccgt tacagcaatt ggatttccgt ttatccctat ccaaatcacg ctgattgatt
    35341 tagcgattga agggtatcct tccttctttt tatcttttga acaagataaa agaaaaatca
    35401 cttaccgtta tttgcctaca gcacttatta atgctttacc aaatgccttg cttgtagtag
    35461 tgaatatcat tgcggtgtat ctacttggaa aaacattcgc atggggaaat gctgaaacta
    35521 ctactttgat gtattacttg ctgattggga tcagttgcat ggcagttgta aaagcttgtt
    35581 atcccttcaa cccattgcgc atcttcctag cagtaacgac gatcgtaggg atatatgtag
    35641 ctgcaatgct gttccatgga attttggaag taaacttagg gttgggagag agcgtaggat
    35701 acttctttgt attcatgctc gtaaatattg ttcttcgagt attgtactgg aaggctgata
    35761 ttcaaaatca gttactgaaa agagtagcaa attgatgctt aatgagatag aaatgtgtta
    35821 tacttgaaaa agcaatgaaa tatgatacaa tcaaacatgt ataattgtgt cctttaaaat
    35881 cgcactgatt tcagttagtg cgatttttta ccggttattc tcctgaaata tcttctgtta
    35941 aacccaaaag atatcaatag agcagggggt gaaaaaatgg ctcaacggat tcctcaagag
    36001 gttatcgaaa cagtacgcag tcaaacgaat atcgttgagg tgattggaca atatgtccag
    36061 ttgaaaaagt ctggtaaaaa ttacttgggg ctgtgtcctt ttcatgaaga acgtacaccg
    36121 tctttttctg ttgcagaaga caagcagatt tttcattgct ttggttgtgg taaaggcgga
    36181 aacgtgttta cttttcttca agaactagaa ggtctaagtt ttccagaagc agtggtaaaa
    36241 gtggcagact tcgaacagat accgttagaa gatcaatggc gtcagcgtac tatagctgtc
    36301 caaaatcctg aatctgctac ggggaaactg attgctgctc atgaaaaagc agcggaaatc
    36361 tatcatcaca tgctattgca tacaaaagct ggacagccag ctttagaata tttgcaaagt
    36421 cgtgggttgt ctttagaatt aattgaagaa ttcaacatag gttttgcacc taatgagcgt
    36481 tcttttcttc agcaagtatt caagaatgaa tcaatttcaa atgaattgtt agaacgctct
    36541 ggattgtttg tcacgcatga tgatggccgt atgtctgatc gtttttatca aagagtgatg
    36601 tttccacttc gtaattctca aggccagacg atcggttttt caggacgctg gcttgcacct
    36661 gaaaaagggc aggaaaaaga tcagcccaaa tacttgaata gtccagaaac agaactgttc
    36721 aataaaagac aagttttatt taatcttgat aaagcaagaa gcgatatccg gaaaaacgga
    36781 gaaattttgt tgttcgaagg gtttatggat gtgattgctg catggcaggc tggtatcaaa
    36841 actggattag cttctatggg gacaagtcta acagctcaac agatccaaca aatggaaaag
    36901 ctgacgaaag aattggtctt ttgctatgac ggagacaacg caggttttga agcaaccaat
    36961 cgagggattg aattgcttcg gcaaaacagt cgattagcac tttctgtcgt agtcgttcca
    37021 gaaaagcttg atcctgatga atatctccgt aagtatggag aagcatcttt ccaagaatta
    37081 gtggctcatg ggcgcgaaac agtctttact tttaaatcac gttatttaaa acaagggaaa
    37141 aatttagata atgaaaaaga caagatcgaa tacctcgaag aattactagt tgaacttagc
    37201 cgagttgttt caccaatcga acaagatatg tatctatctc aactgtcaac agagtttcag
    37261 atcggcagag agacgataca aaaacaactg cgcgatcttc gaaggacaaa tcagcaaaat
    37321 cgtcaagaac ctcaggaaag tcaacacact caggttacga gacaagaaac tgcacggaaa
    37381 aagagacctt tgacgcaagt agaaaaggca gagcagattc tattatatcg tgcatttaaa
    37441 gaagtttctg tccgtaatat tttaaaagaa cgagaatttc agtttattca tgatgcatat
    37501 gcagaagttt attttttatt cgatgcatat gtctcacaac attatgaatt caaccttgca
    37561 gagtttttag actttttgca agatgaaaat ttaaggcggt tggtggtgga aatcgaatat
    37621 ttaccggtgg cagaagaaag ttcgccacga gaaatccaag acttgctaga tgtgatcagc
    37681 aaatctggct tagctgatga aataacatta aaaaaacaaa tgcagcaaga agccagacga
    37741 actggaaaca aacagcttga gcttgaattg acgattgaaa tcatcaattt aacgaaacag
    37801 ttaaaacaag ccaaatagct actcaagggg ggccttcttt tatggcaaat ggaacagata
    37861 aaaaaacgta tgaagcagca gtagcagctt tcatcaaaga aaacaaaccc aaacgacaag
    37921 ttgtatatga tgatttatcc aatcagcttg ctacaccatt cactttgaat gcagatgaaa
    37981 tggacaaatt gatccaaaag attgaagacg caggtatcag tgtggtggat gaaaatggtg
    38041 atccatcaat tcacagcttg aagagtgctg agaaaaaagc tgaacaagca aaaacagaag
    38101 atctttctgc gccaaccggt gtaaaaatca atgacccggt tcgtatgtat ctgaaagaaa
    38161 ttggccgtgt ctccctttta actgcggaag aagaagtagc gttagcattg aaaatcgaag
    38221 aaggcgacca agaagcgaaa cagcgtctgg cagaagcaaa ccttcgttta gtagtaagta
    38281 tcgctaaacg ttatgtagga cgaggcatgc agttccttga cttgatccaa gaaggaaaca
    38341 tgggactgat gaaggcagtt gaaaaatttg actaccgcaa aggatttaag ttttcaacct
    38401 atgctacatg gtggattcgt caagccatca ctcgagcaat cgctgaccaa gcacgtacga
    38461 tccgtattcc agttcatatg gttgaaacaa ttaataaatt gatacgtatc caacgtcaat
    38521 tgctgcaaga ccttggaaga gaacctacgc cagaagaaat cggtgcggaa atggatcttc
    38581 caacagaaaa agtccgagaa atcttgaaaa tcgcgcaaga acctgtttcc cttgaaacgc
    38641 caatcggtga agaagatgac tctcacttag gtgatttcat agaagaccag gaagcaacaa
    38701 gtccagcaga acacgcagct tatgagttac taaaagaaca attggaagat gtactagata
    38761 cattgactga tcgggaagag aatgtccttc gcttacgttt tggtttagat gatggccgga
    38821 cgagaacatt ggaagaagta gggaaagtat ttggtgttac tcgggaacgt attcgtcaga
    38881 tcgaggctaa agcattaaga aaattgcgcc atccttctcg ttcaaaacaa ttaaaagatt
    38941 tcttagaata agcgtggact attgaccaga agagaaatca gtaaaactgt ttggtttatt
    39001 ttaaaagaaa aaaa
//
LOCUS       DAPBBV010000027        37223 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.027, whole genome shotgun sequence.
ACCESSION   DAPBBV010000027 DAPBBV010000000
VERSION     DAPBBV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37223
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.027"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            647..964
                     /locus_tag="RD486_001691"
     CDS             647..964
                     /locus_tag="RD486_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDT7663425.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="RD486_001692"
     CDS             complement(1055..1420)
                     /locus_tag="RD486_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663426.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="RD486_001693"
     CDS             1628..2110
                     /locus_tag="RD486_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663427.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="RD486_001694"
     CDS             2307..3197
                     /locus_tag="RD486_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HDT7663428.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3484..4758)
                     /locus_tag="RD486_001695"
     CDS             complement(3484..4758)
                     /locus_tag="RD486_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7663429.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            5031..7502
                     /locus_tag="RD486_001696"
     CDS             5031..7502
                     /locus_tag="RD486_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7663430.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7605..9341)
                     /locus_tag="RD486_001697"
     CDS             complement(7605..9341)
                     /locus_tag="RD486_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDT7663431.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9338..10042)
                     /locus_tag="RD486_001698"
     CDS             complement(9338..10042)
                     /locus_tag="RD486_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7663432.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            10173..10676
                     /locus_tag="RD486_001699"
     CDS             10173..10676
                     /locus_tag="RD486_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDT7663433.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10636..10974
                     /locus_tag="RD486_001700"
     CDS             10636..10974
                     /locus_tag="RD486_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDT7663434.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10995..12413
                     /gene="ffh"
                     /locus_tag="RD486_001701"
     CDS             10995..12413
                     /gene="ffh"
                     /locus_tag="RD486_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDT7663435.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12525..13103
                     /locus_tag="RD486_001702"
     CDS             12525..13103
                     /locus_tag="RD486_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDT7663436.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            13107..13628
                     /locus_tag="RD486_001703"
     CDS             13107..13628
                     /locus_tag="RD486_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7663437.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(13707..14261)
                     /locus_tag="RD486_001704"
     CDS             complement(13707..14261)
                     /locus_tag="RD486_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDT7663438.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14514..14789
                     /gene="rpsP"
                     /locus_tag="RD486_001705"
     CDS             14514..14789
                     /gene="rpsP"
                     /locus_tag="RD486_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDT7663439.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14801..15052
                     /locus_tag="RD486_001706"
     CDS             14801..15052
                     /locus_tag="RD486_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDT7663440.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            15177..15968
                     /locus_tag="RD486_001707"
     CDS             15177..15968
                     /locus_tag="RD486_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663441.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            16138..16659
                     /gene="rimM"
                     /locus_tag="RD486_001708"
     CDS             16138..16659
                     /gene="rimM"
                     /locus_tag="RD486_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDT7663442.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16649..17410
                     /gene="trmD"
                     /locus_tag="RD486_001709"
     CDS             16649..17410
                     /gene="trmD"
                     /locus_tag="RD486_001709"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDT7663443.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17546..17893
                     /gene="rplS"
                     /locus_tag="RD486_001710"
     CDS             17546..17893
                     /gene="rplS"
                     /locus_tag="RD486_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDT7663444.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            18151..18444
                     /locus_tag="RD486_001711"
     CDS             18151..18444
                     /locus_tag="RD486_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDT7663445.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            19287..21614
                     /locus_tag="RD486_001712"
     CDS             19287..21614
                     /locus_tag="RD486_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7663446.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            21740..22069
                     /locus_tag="RD486_001713"
     CDS             21740..22069
                     /locus_tag="RD486_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HDT7663447.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            22109..23113
                     /locus_tag="RD486_001714"
     CDS             22109..23113
                     /locus_tag="RD486_001714"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7663448.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            23110..24539
                     /locus_tag="RD486_001715"
                     /pseudo
     CDS             23110..24539
                     /locus_tag="RD486_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            24745..25917
                     /locus_tag="RD486_001716"
     CDS             24745..25917
                     /locus_tag="RD486_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7663449.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(26079..26534)
                     /locus_tag="RD486_001717"
     CDS             complement(26079..26534)
                     /locus_tag="RD486_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663450.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            27124..27546
                     /locus_tag="RD486_001718"
     CDS             27124..27546
                     /locus_tag="RD486_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663451.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(27712..28905)
                     /locus_tag="RD486_001719"
     CDS             complement(27712..28905)
                     /locus_tag="RD486_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7663452.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            29129..29506
                     /locus_tag="RD486_001720"
     CDS             29129..29506
                     /locus_tag="RD486_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7663453.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            29494..29832
                     /locus_tag="RD486_001721"
     CDS             29494..29832
                     /locus_tag="RD486_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7663454.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            29966..30409
                     /locus_tag="RD486_001722"
     CDS             29966..30409
                     /locus_tag="RD486_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HDT7663455.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            30671..31486
                     /locus_tag="RD486_001723"
     CDS             30671..31486
                     /locus_tag="RD486_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7663456.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            31496..32158
                     /locus_tag="RD486_001724"
     CDS             31496..32158
                     /locus_tag="RD486_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7663457.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            32363..34027
                     /gene="alsS"
                     /locus_tag="RD486_001725"
     CDS             32363..34027
                     /gene="alsS"
                     /locus_tag="RD486_001725"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HDT7663458.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            34040..34750
                     /gene="budA"
                     /locus_tag="RD486_001726"
     CDS             34040..34750
                     /gene="budA"
                     /locus_tag="RD486_001726"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDT7663459.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            34880..35377
                     /locus_tag="RD486_001727"
     CDS             34880..35377
                     /locus_tag="RD486_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HDT7663460.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            35562..35822
                     /locus_tag="RD486_001728"
     CDS             35562..35822
                     /locus_tag="RD486_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663461.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(36184..36423)
                     /locus_tag="RD486_001729"
     CDS             complement(36184..36423)
                     /locus_tag="RD486_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663462.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            36709..37023
                     /locus_tag="RD486_001730"
     CDS             36709..37023
                     /locus_tag="RD486_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663463.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT        12512 a         6485 c         7380 g        10846 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg
     3421 tgaagacaaa tttgaataaa acttagtccg atatgcggcg cgttctgtgc gccgcatatt
     3481 tttttagttt tcaaagatca gaccttgttg taaatagatc cgtgcccgaa agttataaaa
     3541 gttgcgataa ccaaacgcaa ttcgtttaat cagcttgatc ttgttattca gcccctcagt
     3601 gacgccgttt gagtgggaca ccttaaaggc atttgaaata cccgattggt agcaatggaa
     3661 gatcgtgaat ttctttttaa acgactgagg taacgtagat gaaattgttt taagggtttc
     3721 ttgaaagcct tccgtacctc gtttaacgaa ataatagcgt aataattgac aaaaatgata
     3781 cgcagttcgc aattcttcgt tgtagcttaa cagctcatca acgatttctg tttgactaat
     3841 tggtcgttta aacagtcgat gataatgccg tttgagtggc tcccatgtcg tggaatcttt
     3901 gagtaagagt ttccaatatc gcttgagccg acggtacttc ttctgatttt cagagtgtga
     3961 ggttcgaaaa cgattcatga tctggacacg taattgattg aagctgcgat tgatgtgttg
     4021 gacaatatga aagcggtcag ttacgatctc cgcatttgga aagactgttt taagcaactg
     4081 acaatagctg gcattcatgt ccatcactag gtacttgacc tttaaacggg cctttctagg
     4141 aaagcgcagg aagtattgag ttagtttgta aagtctgcga tcttcaagga tcgtaaatag
     4201 ctgattggtt gtcccatcaa cacaaataaa actcatggaa ccagaaacag aattcattga
     4261 tttgaactca tccatacaca acaccgtcgg aaggaagttc atacgtggct ggtaatgctt
     4321 cgttgcttca cgcaagatcc gtgtcaccgt cccatccgag acgaagtact tcttagcgat
     4381 tagtttacgt gattgatttt cgtacagttc catgagaatc gcctgcttca gttcctttgt
     4441 tagttgatga tgttcatcaa ctaagtccgt tttcgcagaa aaggtccttc cacaatcatg
     4501 gcagagaaaa cgggtacgtt ttaattctaa aatagttaac ttttctttga ctttcaacat
     4561 ctgagtgcgt gtcgtatagg aaccgttgcg gataatacga accgatcgac agtgttcaca
     4621 ataggaagaa gagtcatcca attttccttt aataaactgc gcttgaacgc ctttatattc
     4681 tttttcaatc agccattctt catcaaaaaa taaatgttta tctgttaatc cgagtaattt
     4741 tctagtatga ttatccattg agagactcct ttggtaggat gacgttttgg tcgactaaat
     4801 tttaccaaaa gtgagtctct ttttgagttg aaacgaagaa aaagtgttag tagaaaatcg
     4861 ccttcgattt tccaccaaca caaaatatta tagaaccctt tttttttgct atatgacagg
     4921 aatgaaaggt gtttgcaagc ttaatgtgag gaacactttc catatctgtt ctatactgga
     4981 taggagaagt ttggaaatat ccagaaaacg aaatcaatcg aggtagccac atgaagaata
     5041 aatggataaa tcgaagtaaa aaaaagaaag taacacaaag atcatcagat aaagtcatcc
     5101 gtctttttcc atcgtataaa gaaggattaa cggcagatca agtcaaggaa cgaatagaaa
     5161 aaggtgcagc aaataattca gtcgatccca cattcaaaac aaatcagcaa atcgtattgg
     5221 aaaacatatt tacgtatttc aatttgatct ttcttatctt agccattttg ctttgtttag
     5281 tagaatccta taagaacttg acttttttac cagttatcat agccaataca ggaatcgcca
     5341 tttttcagga aattcgatcc aaaaagatct tggacgaact aaatgtttta aatacagcaa
     5401 aagtcaatgt catacgagac gggatagaac aaacaataga tatagaagac cttgtaatag
     5461 atgacattgt tattttagag actggatatc aaattccagc agatgcagag gtcgtggaag
     5521 ggaaactgca agttaatgag gctttattga caggcgaagc agatgaaata accaaagaaa
     5581 taggtgatcc attaatgtcc ggcagtttca ttgtttccgg aaaagcttac gcccgattag
     5641 acaaagttgg agcagattcg tatatttccc agctgacagt caaagccaag acaatgggag
     5701 aaggagaaca gtcggagatg attgcttctc ttaatcaatt gatcaaatgg attgggatca
     5761 tcattattcc tatcggtatc ctgctttttt ctcaaagtta cttttttaat ggaaacacga
     5821 tcaaagaaag tgtcgttgca atggaagcag cattgatcgg tatgatacct gaaggactgt
     5881 acttgctgac gacgattgca ttagcattaa gtgcgactaa actagcaaag caaagagttc
     5941 ttttacacaa tatgaaaagc attgagacat tggcaagggt aaatgtcctt tgtgtagata
     6001 aaacaggaac gatcacagaa aataaaatgt ctgttcaaaa aatgatcgtc tctaaaaaac
     6061 aagaaataat cagtcagtca gatcaattgg aagcatgcat tgctgactat gcaaaagcga
     6121 tggcaggaga caatgcaaca atggaagctg ttaaagcata ttttacaaaa accactgatc
     6181 aatcctatca ccatgttatt cctttttctt ctgtccaaaa attcagcagt gtagcgttgg
     6241 cagacaaggt gtatgtttta ggagcgcccg aaatggtttt gcgcgatcaa ttgccggaat
     6301 atgcggaaga gtttgtttct ttcgctgaaa aaggctatcg cgtgttggtc tttggtgtgt
     6361 acgatgggat tcttgaagaa ccagtattga cagaagcagt cacaccatta ggctatattc
     6421 tgattgctaa tcctatcaga aaagaagcaa gagccacatt tgattacttc aaaaaacagc
     6481 aagtagccat caaagtgatt tctggagata atccgctcac cgtatccaat gtagctgtcc
     6541 aagcagggat ttcacatgct gatcagtacg ttgatgcatc taaattatca gaagaagaat
     6601 atgaagcagc tgtcgaaaaa tatacagttt ttggacgcgt caagccagaa caaaagaaaa
     6661 tcttcgttca attgataaag cgtaacaata cagtagctat gacaggtgat ggcgtgaatg
     6721 atattctagc catgaaagaa gcagactgca gtatagcgat ggcttccgga aatgaagccg
     6781 ccatgcaggc ctcacaagtg gtcttacttg attctgactt ttcacgcatg ccagaagttg
     6841 ttgcagaagg acggcgcgtt gtgaacaata ttgagcgatc agccagcttg tttttagtga
     6901 agaatatttt ctcctttttg ctctcactgt tttcagtgat ctttgctctg acctatcctt
     6961 tagaaccatc acaaatcaca ttgattagtt tgtttactat cggacttcca tctttcttgc
     7021 ttgctctaga agaaaacaaa aagcgaatca gagggaaatt catcatgaat gtgatggaaa
     7081 aagctgtgcc aggtggacta acagatatga tcgtagtcgg tgcgttggtg atctgcgggg
     7141 tgactttgaa tctaaataaa acagatgttt ctacagcatc taccatgctt ttgattgcag
     7201 tagggttcct cgttctctat aaaatctgtt caccgctgaa taaattcaga agtcagatca
     7261 ttcttttctg tgctagcggt aacttttttt cggtcatctt tttgcataag ctgttttcaa
     7321 tcaccggtat ctcagctgta tcacttttgc tgttgagcat tctatttttc tcggcagatt
     7381 cgatttttag gcatttgacc acattggtag aatatttgtt tgaacgtaaa aatgaaaaag
     7441 agcaaaagcc gtttagtcgc gtagctaaaa aatttctatc gatatttaaa cgagaaaatt
     7501 gacgaaaagt atctcaaaaa agagtaaaaa agaacaacca ctcgtgtatc tttcgaagca
     7561 ggatgagtca tccaacttta aaacgcacga gcagttgctc ttttttacat tttcggaatg
     7621 gtaacggtga aagtcgaacc tgttccaaga tgactgtcta cagtaatcgt accattaagg
     7681 agttgcacgt agtcttttac aatcgctaac cctaatccgg tcccgcctga atgtcggctt
     7741 cgcgccttgt ctacgcggta aaaacgctca aagatccgtt cctgatcctc aatgtcgata
     7801 cctataccaa agtcttggac agaaaacgat agatcatctg ttgcctgata gcggataata
     7861 atctcgctgt cgctttttga atattggaca gcattttcaa tcagattttt gataattgga
     7921 taaaggatat ctgttttagt agtaaatggt tcgttctttc caatcaatcg aatcgtcaac
     7981 cgtttctttt cgatgattgg ctgataattt tgaacgattt gctggaaata aggttctgta
     8041 taaattgtct ggatctcgta agaattctcg ccatcttttg acagctggat gatttcccga
     8101 atcagtttat ctaaccggat cgcatctttt tgcatgatct caagaaaaga agtcagagtt
     8161 tgcgggtcat cttttgcacc atccagtaaa gtctcggtaa aaccaatcag tgaagtcaca
     8221 ggagttttta attcgtgaga gacgttgcca acgaaatcct tttgtagctt ttctaaacgt
     8281 cgcactttcg ttaagtcata cgccacccct agaatctgtc cggtaccttc tgaattagta
     8341 aagtagcgca aactcaagtc taatgtctgc cgaccttctg taagggtgat ctcctgatgg
     8401 atcagcggat gctcaggagt cacttgatga atcagctgaa tgagttttgg ctcttgaatg
     8461 acttctgtgt accgctgttc aggttgatag cttaccacgt ttaaatgtag ctgcatcttt
     8521 ggattaagca gtagtaaacg agaatcagca tcatcaatca ggaatacgcc aatcatcagt
     8581 tcgttcagta acgtatataa ttgctcttct gtggtagtac acgcccgata catcttactc
     8641 atttgttcgc tcaacgcatt aatcgtctga tacaattctt cccattgatc gggtgtttgc
     8701 atgattactt ccgcctgatt aggattttgc accatttttt ttagtacggg cagcacggtt
     8761 ttcaatggct ggtttttttg atagatcaga taatagatca ttcctgcaag aacaaggaag
     8821 aaagacagaa agaagaaaaa gacccaacgg cgaaaactct cagttctcgg taaaaaaacg
     8881 cttgtcggtt ctgcgatacg taaaatggct tctaactggc cacttttttt gactggtaat
     8941 gcgacatata aaagatcctc attcaaagta gtacttttgc gcaaagcgct acctaggttc
     9001 ccaccattca atacggcttt gatttcggga cgggagtttc gctgttcatt caatgtttca
     9061 ttgtttgtgt caaataagat ctttccagta gcatccatta aagtaatccg ttcgttcgac
     9121 tgatggacga attcttccaa agcagttttg ttttgcgctg cttggaggtt ttcgacatct
     9181 aattgccgga tcagcagttg tgcttttttt gtcaggtagc tttcttgctg ttccacgatc
     9241 tgctgttgaa aataatggga aatcaattgc cagccaccaa aaaacaaact aactaaaaga
     9301 ataagaaaga agagacgttc ataaattttt ttccatttca tcgtttgggt tcctgaaact
     9361 tatagccaaa tcctctaata gtcaccaagt actttgggtg ttttggatct cgctcgattt
     9421 tttctcgcaa atgactaacg tgtacatcta cgattcggct ttgtcctgcg aagtcaaaat
     9481 tccaaatgcg gtctagcaat gtgtctcggt cgatcacacg gtcttttcgt ttcatgaaat
     9541 aaacaagtaa ttcaaattct ttcggtgtta gttcaatcag atggtcgtct acggtcactt
     9601 gataattggt caaatcagca gtgatttgtc caatcgatag atattcaggc tcagcttcat
     9661 cttttgattg cttacgaggt tcaattcgtc tgaatattgc tttcatacgg gctaatactt
     9721 cgcgaggact aaatggtttg gtcaaatagt cgtcagcacc tatttctagg ccaatgatcc
     9781 gatccacttg gtcatcttta gccgtcagca tcaaaatcgg tgtttcattt ttttcttgac
     9841 gcagccgctg agtgatctcc atgccatcca tcgttggaag catcacatct aaaatgatga
     9901 aatcaaatga ttgttctaat gctaattcta atccttcgcc tccatctgtg gcactggtta
     9961 ccttgtagcc ttctttttcc aaattgaacg tcaagagcgt tacaatagaa ggttcatcat
    10021 caacaactag tatttttttc attcaaatct cctttaaata ggtttcattc tgtttatatt
    10081 ttagcataga atcagtacaa agggctattt tacaaaagaa ataaatggta taataggaag
    10141 gcactttgct gaatagaaag gaagagcagt caatgattgg aatcagtgca tgtttaggcg
    10201 gtctggcctg tcgctatgat ggacagaaaa aagaagtacc agaattgatg gaactagttg
    10261 aaactggaga agctgtcatg gtctgtccag aagtgatcgg cggattacca attcctagag
    10321 atcccgctga aatcattggt ggaaatggat tcgatgtgtg gaaagatcaa gcaaaagtat
    10381 ggacgacaag cggcgaagat gtaacggaag cgtacaaaaa tggcgcgatc aaagcctatc
    10441 aaaaattgca ggaaaaacac attgatctag tcatcatgaa ggaaaaaagc ccttcatgcg
    10501 gaacccattc gatttatgac ggaagttttt ccggaataaa aaaaaatggt gccggagtgg
    10561 ctactgctta ttttattcag caaaaaatga ctgtgctctc tgatgaagaa tggctgaaaa
    10621 ctagaggtga gcagaatgga aatcgaaaag accaatcgaa tgaacgcgct ctttgaattt
    10681 tattcgacct tattgacaga aaaacaaatg aactacatgg aattatatta tgcagatgat
    10741 ttttcattag gtgagatcgc ggaagaatac gaagtaagcc gacaagcagt atatgacaat
    10801 atcaagcgga caagcaagat cttggaggat tatgaaaaaa aactccatct tttttctaat
    10861 tatattgttc gagaacaggt attggaaaat atgactgcat atattacaga taagtacccg
    10921 gaagataaaa aactacttga atatgtacag caaattcaag caatcgaaga ataaataaaa
    10981 ggaatgaaga aaatatggca tttgaaagct taactgaacg tctccagcag gcgatgggaa
    11041 aaataagaaa aaaaggaaaa gtatcagaag ctgacgtaaa agaaatgatg cgggaaatcc
    11101 gccttgcctt actagaagcc gatgttaact tgcaagtagt caaagatttt actaagcgcg
    11161 tacgcgaacg tgcggtaggg gcagaagtgc tggaaagttt atcacctgca caacaaatcg
    11221 taaaaatcgt tgatgaagaa ttgacgatca cacttggttc tgaaacagca gagttaaata
    11281 aatcaccaaa aataccaact gttatcatga tggctggtct tcaaggggca ggtaaaacga
    11341 cctttactgg taaattagcc aattatttaa agaaaaatga aaatgctcgt ccgctcctaa
    11401 tcgcagggga cgtatatcga ccagctgcga tcgaccaatt gaaagtatta ggtcaacagc
    11461 tagacgttcc tgtatttgat atgggaactg aagtcagccc ggtagagatc gtccgtcaag
    11521 ggatggagtt agcaaaagaa aagaaaaacg actatgtatt gatcgatacg gcaggacgtc
    11581 tgcatatcga tgaaacattg atggatgagt tgaaacaaat caaagaattg acgcaaccaa
    11641 atgagatttt gcttgttgtc gatgccatga ctggtcaaga tgccgtcaac gtagctgata
    11701 gcttcaacca gcaattaggt attacagggg tcgtcatcac taaacttgat ggggatactc
    11761 gaggcggggc agcactatcg atccgctcag tgacaggcgc accaatcaaa ttcatcggtt
    11821 ctggtgaaaa attgactgac ttagaagtat tccacccaga tcgtatggct agccgtatcc
    11881 ttggtatggg ggatatgctg acattgattg aaaaagcgca gcaagactac gacgagaaaa
    11941 aagcggaaga acttgcacag aaaatgcggg aaaattcatt cgatttcaat gactttattg
    12001 aacagcttga tcaagtgatg ggtatgggcc cactggaaga tctaatcaaa atgatcccag
    12061 gaatgaatca agtccctgga atcgaaaacg tcaaggtaga tccaaaagat gttgaacgca
    12121 aaaaagcgat ggtttattct atgacgccag cagaaagagc aaatcctgat ctgttgaacc
    12181 caagccgtcg tcgccgaatt gctgccggtt ctggaaacag tgttgttgaa gtgaatcgaa
    12241 tgatcaaaca attcaaggaa tcaagaaaaa tgatgcagca aatgtccaaa ggggatatga
    12301 acatcccagg tatggaccaa atgtttggtt caggcgtcaa aggaaaacta ggcaaaatgg
    12361 cgatgaatcg aatgatcaag aaaaataaga agaaaaagaa aaaacggaaa taagatgaaa
    12421 aaaacagctt cggtacagac tgaaaatgtc tactgccgga gcttttctat cagcaatttt
    12481 tattctttac taatacaatt actctaaacg aagaggtggc acagatgaga tgtccgtgga
    12541 gtgaacaaac agaaagtatg cggcaatatc atgatactgt ctggggtgtt cctgaatatg
    12601 atgaccaaaa gctgttccga aaattgatgc ttgatattaa tcaagccgga ttgagctggc
    12661 agacgatttt aaataaaagt gaagcattcg atgaagcata tgatcgattc gatatcaaaa
    12721 aagtcgcaaa ttatggagaa acaaaaatca gtgaactaat ggaaaacaaa ggaattattc
    12781 gtaaccgaag aaaaatcgaa gcagccgtcc aaaacgccaa agcagtcttg aaaattcaag
    12841 aagaaatcgg cagtttttca gagtatcttt ggtcgttttc taatggaaaa atcgttgatt
    12901 cttcttatca ttcacaagaa gaagtcccaa caacaagtcc tctttcagat gaattagcaa
    12961 aagatctaaa gaaaagagga tttaaattta tcggaagcac aacaatctat gcttttttag
    13021 aagctgtcgg gatcatcaat gatcaccttg acagttgttt ccgcaaagaa gaggtcgtac
    13081 gtatcggcag aaagggcgaa taaagcatgc gaaaaatcat attttatggt gctataagtt
    13141 tagatggcta tttggcaacg aaaacggatg atcttcaatg gctttttgac actccaacag
    13201 gtaagcaaac tacttatgaa gctttttatg aaacaatcga tacgaccatc atgggcagaa
    13261 aaacttatca ggaagcaaaa aaatatttgg agaccgaagc aatttatcca gagaaaaaga
    13321 atttcgtttt ttccacccac gcacaattac aattgccaga tgctgaggtc gtaaacgaag
    13381 atcctgttgc ttttctaaaa aatctacaaa tgacagaagg aaaagatatc tgggttgtgg
    13441 gtggcggtcg attgatcaaa ccgctattgg aacatcaaat gattgatgaa tggtatatcc
    13501 agattacccc tgtattatta ggggacggga ttcctttatt ccaaaaagga acatatgaag
    13561 cgcgttttga aatgctagac acgacacgat tcggtgaatt tatcgaattg cattatgtac
    13621 gaaagtagaa gtaaataaaa taaaaaaggc aactatatgc agaaatgtcc tgtacatagt
    13681 tgcctttttt attaccgtta tgctttttac tctgttaatt tgttagaaaa atctagatac
    13741 gcatctaaaa tcgtttggaa gaaacttaat gttccttcaa cgatattacc attttcatca
    13801 attagattcg caacgtttcc gatatatgct tccggttgct gcaaggttgg cacattcaaa
    13861 aagacaagtg attggcgtag atggtggttt gcgccaaagc cgccgatccc acctggtgat
    13921 gcagtaacga ctaaacctgg tttatgatcc caaacactgt gtccataagg tcttgagcct
    13981 acatctaaag catttttcaa tactgctggc acagaacggt tgtattcagg agtaacgaaa
    14041 acgacaccgt ctagtcccct cacttcctca cgaaaacgag tccattcagc aggagcctgt
    14101 tctggagttt cgagatcctc attgtaaaat ggcagatcat cgatttttac aaatacactt
    14161 tcgtaccctt caggaagcaa tttcgcaaaa gcttctgcta cttttttgtt gtaagaatct
    14221 tttcttaaac taccaataaa aaatccaatt ttttttgtca tacgattttt cctccttcaa
    14281 actatctata ataatcttac aaaagataag taactggagc aaataaaaac acttactgac
    14341 aaaagctaca tagaagatag attacttatt tttaacaaaa aagaagtcta aaatcttcta
    14401 ttttctaaaa aaaatcgaat ttaatcaagc tgtaaagaaa aaaagcttta cagggtaaaa
    14461 aaaaactgtt acactacatc ttgtgaataa aacaatggag gtggaaataa ataatggcag
    14521 ttaaaatccg tttaaaacgt atgggttcta aaaagagtcc gttttaccgt atcgtcgtag
    14581 ctgattcacg ttctcctcgt gatggacgtt tcatcgaaac tgtaggtact tacaatcctt
    14641 tgaaagaccc tgcagaagta gttttaaaag aagacttagt tcttgactgg ttatcaaaag
    14701 gtgcacaacc ttctgacact gtacgtaaca tcctttcaaa agaaggcgtt atgcaaaaac
    14761 accacgaagc taaattctca aagaaataag gtgaccggat atgaaagatt taagcgactt
    14821 agtcttaaca atcgttcgtc cgctagtcac ttatcctgat caagtcaagt tagacgtcgt
    14881 agagtcgaaa gacttttacg agtacaatct aacagtggct cctgaagata ttggccgtat
    14941 cattggaaaa caagggcgtg ttgctaaagc aatccgcaca atcgtttacg gtgttcggat
    15001 caatgcaccg aaaaaagtgc gtttgaatat catcgatgat aaggaaaagt aaataaacgt
    15061 gctgtactcg aattttcgag tgcagctttt ttgttttttt tattaattga agaaatgatt
    15121 atttggcaaa acaagcaaga aagcgtatcc ttataggagg agggagtgaa cagccaatga
    15181 gaaagaaaat gttatttatt ccatttgctc tattgttaag cgcttgtagt tcggttactc
    15241 aagaatcaga caatacacat ctatcaagca gtatatctga aactgttacc agtccagaaa
    15301 aaagtagtac caaaacggct tccaccactg aacaaacaat ggctacctca aataatgaga
    15361 aaaagactgc tttagaccag ttgaaagaac aacagccaaa tgttcccatg cctctagatg
    15421 taccagtctc ttcaggctat ctcaatatcg cagcgacaca tacaaagcaa ggttattcta
    15481 ttttatatta cagaacagat cgtcccctcg ggttgaatgc tgacgaattg aatcaagaaa
    15541 cgcctattgc aacctatcta tatcaatatg ggtttgcttc tagtcaagaa acaatccaag
    15601 ttttgcagcc atttgagatc gacacaaatg gtcagcaagt ggacttaggt tctcgaatca
    15661 cagggtatca gcaaggtgca gcaggttcaa gttttcttga atggcaagaa ggaaactggc
    15721 gtattcgaat ccgtgggaat aatatagaag gccaagatcc cttactatta gctaaagaaa
    15781 tcgtagctta tttggaagaa aacagtctac cagcacctga acaatttggt aaaattactg
    15841 ttgatatggg tgatacgacg aatcgagccg tagaagtaag ctggcaagaa ccgaaaaatg
    15901 cctatacgat cactcatcaa gatcctatgt ctgcgttgaa gatggcagtt tctatgaaga
    15961 ggttgtgaaa tcagcgcgct gatctgagcc catcatttaa ctccaagtca caggaagtaa
    16021 tcaaaaatag cacgccgcat ttttgcataa ttttggctta ataccttaaa agaaaactag
    16081 aattgcctct tcacacatgc taaaataaaa cagacaaaaa agaaatgggg atataagttg
    16141 actgaatact tgaatgtagg aaaaatcgta aacacacaag gtatcaaagg cgaagtccgt
    16201 gttatctcaa caacggattt cccagaagaa cgttacaaaa aaggaacggt gctaacacta
    16261 ttccaagacg gaaaagcacc tgtggaatta acagtcaaaa gtcatcgcaa acataaaaat
    16321 tttgacttat tgagttttga aggacatcct tctatcaatg atgtggaaaa atatcgggat
    16381 ggcatattaa aagtgtcaaa agacaactct gtagatctag ctgaaaatga attctattac
    16441 catgagatca tcggtctgca tgtattagaa gatggaactg agttaggtaa agtaaaagaa
    16501 atcttgtcac caggtgccaa tgatgtttgg gtcgttcaac gtccgaaaaa agctgatata
    16561 ttgcttccat atatcgcttc tgtcgtcaaa gaagtcgatt tagaagctgg agtggtccgt
    16621 gtagaaattc cagaaggact gattgacgat gaagattgat gtattgactt tatttccaag
    16681 aatgtttgaa ggtcctatgg gggaatccat catcggtaag gctgtagata aaggattatt
    16741 agatatcaat atctctaact tccgcgatta ttcagataac aaacatcaga cagtagatga
    16801 ttatccatac ggcggtggag caggtatgct gctcaaagtc cagcccatct atgataacat
    16861 ccaagccatt gaaaaagctg caccggatgt caaaaaaaga gtaattcttc ttgacccagc
    16921 tggtaaacga ttcgatcaga aaatggcaga agaattttca caagaagaac acttagtatt
    16981 catttgtggt cattatgagg gatatgatga acgtatccgc acattagtga cagatgaagt
    17041 ttccttagga gattatgtcc ttactggggg agaattaggt gcgatggtca tgatcgatgc
    17101 aacagttcgg cttttgccag atgtgttagg gaatcagact tcagctcaaa cggattctta
    17161 ttcaaccggt ttattggaac atccccaata tactcgcccg gcagaatata aagggatgaa
    17221 agtaccagaa gtattgacaa atggaaatca taaattgatt gaagaatggc aattaaaaga
    17281 atcactaaga aggacctatc aacgtcggcc tgatcttttg gaaacacttg aatggacacc
    17341 tcaaatgacg aaatttttag aagaaatcaa gaaagaagaa caagaaaaaa cagcagatga
    17401 agccaagtga ctttttctaa aatcttcttt acagtaggtt gataatatgt tagtatttta
    17461 tggtgagtgc aaaagcactt aactattacg atattccgct gtgagaaaag ctcataagaa
    17521 tatttggaat aaggagaaga aaaccatgaa tccattaatc gaagaattaa caaaagaaca
    17581 attacgttct gacatcccag cgttccgccc tggtgacact gtgcgtgttc acgcaaaagt
    17641 tgttgaaggt actcgtgaac gtatccagtt atttgaaggt gttgttatca aacgccgcgg
    17701 tgctggaatc agcgaaactt atacagtacg taaagtttct aacggagtgg gcgttgaacg
    17761 tacattccca ttgcatacac cacgtgttgc aaaaatcgaa gtagttcgct acggtaaagt
    17821 acgtcgtgca aaattgtact acctacgtgc attacacgga aaagctgctc gtatcaaaga
    17881 aatccgtcgt taatcattgt tatcagactg agaaagaacc cttggtattc aagggttctt
    17941 ttttcttagc atgtaatttg aacaccctga tccagttttt tctttaatta ttggtagggg
    18001 agaataatgg attagaataa atctacctat aagtagtagt aaaaaaaaga gcactatgat
    18061 aatatctttc ttaagagtaa ccgctttaat aaaaaatcca gaatattcta acataaatgg
    18121 agtattctta gaatcaaaag gagaaagaag atggtttata cttatacgga gcaagaaaag
    18181 atgaaagttt tagacacatt catgaatgat ggaaaagtaa aacaagtacc aagttcaaca
    18241 aaaaagaaat acatcctatt gaaagaagtc ttgaaacgct ttgaccatgg agtgacttat
    18301 acagaaacag aggttaattc gatactgctg aacgtatttt ctagtggcga ttatgtcgaa
    18361 caaagacgtt atctaatcac atttggcttt ttcaaaagaa gttcagacgg tcgggcatat
    18421 cagatgatgg gaattgaaaa ttagaagttt taatttatac tcattgaaaa aagttcaagt
    18481 atgcgatatt ggttctacac cgcatacttg aacttttttt gtcatctgta tctataatac
    18541 aaagccaaga acgttattca aaatatggat agctatgata aaagctaatg agcgattcgc
    18601 agttaaataa gcaatcgtca gtaaaatcgt tccaggagcg tacatgaaaa aatcaattgg
    18661 atgcgttaca tgaataaaga taattctctt ttatttgtac gaataaatac caaaacgtac
    18721 ctcctaaaat tagattttgg acagatgccc tttaaaaaga taacaagatt tcgttcttga
    18781 aacaatatat atgcttttat tccaatgagg ttgtgaaaac agtattttgt cctgagcgtt
    18841 agaaaattga aaatggggaa tagcaactcg tactttacca ttttttaagt gaatacaaga
    18901 tcagctaatt gaacaccgtt tattcgtgat gagggacaca acactgcagt cgacacattt
    18961 ctcttttatg ttcaaagata acaaatattt aaaacaaaga aaaatagtag ataatcccgt
    19021 cctaactctt ttattcttcc ctcatagctt ccaaatttaa gcaatacttc aattaatcaa
    19081 gttttatctt tttttttcaa taatcgtaaa aaaagagtat tttttattta aaaataaaat
    19141 ctttgtatta aaggacaaga ctaaaataac cttagaataa aaagagaaaa aaagccccaa
    19201 actttctata catcaataaa ataataaaaa ttaaatttag aataacgtgt aaaggattat
    19261 ttgatgattt tttattgaga ggagggatga aaatgattaa gaaaactcaa aataaaatcc
    19321 aacgtatatg tcaaaaacat tttgtttcta gactcaaagc tgtatctaaa agaaaatact
    19381 tacatcccat tatgatttcg atcatcttga tttttacttt cttagggagc ttatcaagta
    19441 tttatgtaaa cgtttataca gaaacgtcaa attttgctaa ccaaacgaca gaggagacaa
    19501 atagtccacc ctattctgaa atacagtcca tagaaagcac caatcagtct agcaacaacg
    19561 agacaacctc aaccacatcc tcgactcaac tgattgatcc gacagaaaaa gaaatcacag
    19621 cagcaaaagc agcaggggag aaagcttatt cagaaacagg tagaagccag acatttagta
    19681 ctgttgcggc cactgcgaat ttcaacggac ataccatacc agatggatat acagtgatat
    19741 atgccaaaga tggagtcatt gttgcggtta acggatcgat gagtgcggat aaaactgcgt
    19801 tacaaggcgt aaccaaagca atcgctttta ttgataaccg tccagatatc cataatctgt
    19861 ttattggctc cacagtaaat ggtactacta tcacattccc aaaaagtatc tatatggggg
    19921 tggctaccgc tggaaatacg atcgattcag ttacacccaa tgcggataaa agttattctt
    19981 ttacaccctc aacatgggga gggcttcctg ccggaggagg tatgagtact ttttcaatcg
    20041 gtatacagtt agcaaatgat attccattca cggggtactc gatcaaaaat gggcagatcg
    20101 ttgatggtaa gggaaatgtt tcaaattttc caacctatca agcagcaacg gttcaggtca
    20161 atgcgaatcg gacaggaact ttttcttata cagtcaatgg tggagcagca aaaatcggaa
    20221 cgtacgggac tacattatct ggaatccatg tgggtgacaa agtggttatc actccaacag
    20281 cagtaacggg ctattctttt gcacaaacaa acggttcttt cacagcccta gaaagtaacg
    20341 tcgatacggt gacctataca ggcaaacaaa caccaatcac tattaagtat caagactatt
    20401 ttggacagat gattgctcct tctaaaataa tgaatcttac ttacggaagt gctgcacaag
    20461 acctgacgac taatacgcct actatcaacg gatatacctt tacagctgtt tcagcgacag
    20521 aaacaaagaa ccaatcagca atgagtgttt tagctagttt agatacaaat ggaaatgtaa
    20581 tcgtaaagga cgcaaatgga aaacagattt ctgaagtcat cctatattat aagacaaatg
    20641 caacagtatc aatcaatgca aatggcagta agtactatga tggtctttct gttgtaccga
    20701 tcgttaaata tgcctttaat gataaaacag aatcaacatc ccttttaaac aatgatctca
    20761 gtattgatca aatcacatgg aatccaactg atttcaaagc gatgaatgaa aagggagttg
    20821 aagtaactgc gcctactgaa attggaacct atacgtcttg gcaattgaca aaaagcggac
    20881 tagctaaact agctgccaga acaaactatt tatttactat cgtgcagaca tctgatgtct
    20941 atacgattaa gcaaatcagc ggtgcggtag agctcagtgg cagtaagaca tatgatggaa
    21001 aagcaggtgt cccgtcaatc catgtcaagc tagcagaggg tgtcactagt tcgcttactc
    21061 cagtacaagt ggcacttagc agtatggatt acacagcaga tgcacaatca gcaaaaaata
    21121 tggttaatgc tggcagctat acaattaaac taacgaatag cggaatagac aaagtcaaag
    21181 cagcaaatcc caagttgtca tttactgata tagccaacac atcaggaact tataccatct
    21241 ataaagctaa cgcagtgatt actgtcgatg acgctgcctt taattatgat gcccaaagtc
    21301 actcgatttc ggttggaaat ctccacgtta ccggtgttgt cttaggcgaa tcattggatt
    21361 ataccctaac agttaacagc cggacagata ttggatcaca aatagtaacg attagtttag
    21421 gcgaaggaag tgtaaacaat aattatacga ttatcgcaac agataccgct aagttgacga
    21481 tcaatccgac tctcttgctt ccttcgacag gtgggatagg tctactgccc tttgtctttt
    21541 taggactgat ctttattttt tctggcttct tttattttat ccatcgtaag aaaaaagcag
    21601 gtgaacagcg atgaaaaaaa caaaaaatgt acgtgtggat atatttgctg ttctcttttt
    21661 tatcctactg gtctttttta taggttctcc gactgtgtca gctagagaat cacctattac
    21721 atttactttg cataatcgaa tgttcgaaag cgataagatg ccaagtatca gtcaaaacga
    21781 cggaataaat atcccggata actttcaagg agtaaaaggg ttgaacggcg ttactttcgc
    21841 tatatatgat gtctcggatg aattttacaa gctgcggtca gaaggaagta gtgtggaaga
    21901 cgcacaaaga aaactagcac aaaaaagtga tagtgaaaaa atactggcag aaaatgtgac
    21961 aaaaacagta gacgaggaag agggcattgc ttcttttagt gcatcggaca aagatgagca
    22021 aggtcgtgac gctgtttacc gatttgcgga aataaagact tcagattaag taaaagaaaa
    22081 atcagcacca tttgtcgttg tgcttcctgt gacagattca tctaatcata aattgacgac
    22141 catccacttg tatccaaaga gcgaacaaaa aatacctgct gcactcacat taacaaaaac
    22201 agtagagaat aagcagacag attttgcaga tggggataaa gttccttatc tcatcaccgt
    22261 aacaattcct gagaacatca acgagatagg aacctatacg atcaaagata cagctgatcc
    22321 tcagttatgg ctagaaccag aaacgatcga ttttttgatt ggtggagaca agattcatac
    22381 atttcacaca caaaaaacaa aacatggttt tgtcttatca gattctggaa aagatcttag
    22441 ttcgtttgct gggaaaaaat taacgatccg ttaccaaatg acattgaaag aaaacagtga
    22501 aaaaacgaca tttgataacg atgtacgttt gacgactgac aatcaaacag tagaaacaca
    22561 tcttgccatc caaacaggag gcaaacaatt tgtcaaagtg gatcggcaaa cgaaacaaaa
    22621 actagcagat gctcaatttc tagtcaaaaa aaatgaccaa tacttagcgc aagaaaacgg
    22681 gataaatcat tgggtagcca aagatgattc aagagcaacg atttttactt ccagtaaaga
    22741 tggaacattt tctgtccatg gattgtcttt tggaagttac gaactagtgg agattaaacc
    22801 gcctaaagga tatatattga gtcaatcaac cattctcttt gaagttgaaa aaggcagtta
    22861 tgatccgctt catcctatac cattggaaat catcaacgaa ccaaaagcaa atccgacgaa
    22921 taatggaaaa acgccagttc agatgcagac aaatggtcca tcaaatgaaa aaaatggagg
    22981 aagctttcca aaaacaagcg aagagatgct tggaggtttc tcaattttag ggttgttgct
    23041 agtcctttca acagggacag cttggtttta taaaaaacaa caaaaaggaa acaataggag
    23101 ggaaataaaa tgaaaaacat caaaacaaaa atatggacgt ttttaggaac tgctatcatg
    23161 ctgcttcctt tcgttctcgg cctaggaact gcagaggttt ctaggccgta tcacctacac
    23221 cagaaaatgt tacggttaat ttgcataaat tgaaattcac ttcagcacca gaaaatcaaa
    23281 taaacaacgg aacggaattg acatttccga atagcgaacc gttgaacggc gttgaattca
    23341 acgtatatga catcactgct acgtactatc caagtaaaga cacagcagtt ccagcagacg
    23401 ctacaccctt cgcaagtgta acgacttctg gtgaaggatt agctaacctg actcttccag
    23461 gtaaatctga tgggaaagat gctgtatacg tctttgtaga aacaccaaag cccggtgtcg
    23521 aaacgtcgcc aaatatcgtg ttaagcttac ccttttataa cccgaattca tcagaccctg
    23581 acaaaccttt agacacgatt cacctatatg ctaaaaatgt catcaaagaa agcaatatca
    23641 aaatccagaa agctgggaac ttttcagggg tagataagtt agcaggggcg caattccaga
    23701 tcaaaaattc agagaatcaa ttcgtgaccg gttttgatga aaacactggt gtcgctctct
    23761 atgatcctgc tgagtcagcg ttgacattca caactgatac tgaaggatcc atcagtgtca
    23821 atggattaat agacggcaat tatactttag ttgaaacaaa agcaccagat ggttatcaat
    23881 taaccaatcc acaaaaagaa actactttta tagtaaaaaa cggaaaattg caacaaacaa
    23941 ccggtatcat ccatggcgca gatgaagcca atcttgggaa tccaaacggt gtagtcaatc
    24001 gggaaaatac aactacggat aacacgatta ctgtagaaaa tgtccaaaac tacggtgatt
    24061 tccacttcat caaacaagat gtgaacacgc aagaaaaatt agccgatgca gaattttcta
    24121 ttctaagagc aaaagatcca actgttaaat taatgaaaaa aatagcaaat cttgcctcag
    24181 gagaataccc atatgcttgg tcagatgaag tcacaggttc tgactgggaa gaagtgaaat
    24241 tgatttctga ttcagaaggg aaattttcaa tcgaagggct gaaacaaggg gcatactgcc
    24301 ttcaagaaac aaaagcacca gaaggctacg cattacctaa gaatgaagct gcgtacactg
    24361 aatttacagt agatgatgat ccaacaactt ctgatgaaac aacgatcgat aaccaaccta
    24421 aaggaatctt gccttcaact ggtggtatgg ggatcatcgt attcatcttg gtaggtactg
    24481 ctttagttgg aggagcagtg atctacttca aaaaacgcca tcaagaaaca gaagcttaaa
    24541 ctattggaaa caaaaatcat acgataaata aacgatagtg attcaaatgg ggagaaaggt
    24601 tgtgacaagt ggtcggtctc ttggtattcg ctcaacaaac ggcaaaatag gaggaactat
    24661 tttgccgttt gttgagcgaa tactcaggtc aaggcgctga tttcacaacc tcttcatata
    24721 catattagaa aataggtgga catgatgaat aaaagcagaa taagaatact ggacatcttc
    24781 atggcaatca ttttagtcgt tgggatcggg atcttttctt atccttttgt agaagattca
    24841 ctgaatgatt ttcttgccca gcaaatgatc atccattatc aaaagcaagc atcgaataag
    24901 aattcagagg aaataaaaaa acagcaggaa aaaatgacaa agaaaaacca acagttggca
    24961 gagcaaaacg tatcaccagg gataggcagt ttcaaccaag cagttgatgc aaaagcatta
    25021 aaagatttac ctagtaatgc cttttttatg gaacatatgc ttggagtcat cgaaatccca
    25081 aaaatcaatg tcagcttacc tatattcgat cagacaacgg aaatattttt gcaaaaagga
    25141 acgtcattat tggaagaaag ttcttatccg actggcggga aaaacaccca tgccgttctt
    25201 tctgggcatc gtggactccc agaagcaaaa ttatttacag atttgcctaa gttgaaaaaa
    25261 ggagaccagt ttttcatcca gatcaatgga aagacattgg cgtatcaagt agaaaaaatc
    25321 caagtggtct tacctgatga agtagattct ttgggtatcc aaaaaggcag agatctcgtg
    25381 actttgctta cctgtactcc ttatatggtc aatacacatc gactgcttgt gacggggcat
    25441 cgtattcctt atcaagcaaa agaggcaaaa aaagcgatcc aaggaattga tcaatggaaa
    25501 aaatggaaat tttttatttg gtttatcggt atactacttg gatcaatcgg cttagtttgg
    25561 ctactcatcg cttatttaga ttctttggcc atcgctaagc gaaactatcc tttatctttt
    25621 tatgtaaaga acacaaacgg acgaccaatc gaaggaatgg tcttttctgt aaaaacgctc
    25681 aacggcaaac actatattac tagagaaaaa gttccatttg tgaaagcttc tgatgaatac
    25741 ggactagtga gattttctga tttaaaaggc aggaactatc gcttgcaaca tgaggagctc
    25801 ctgcttaaaa tccatgtaaa acataaacat tcgaaacagt tttcaatgaa attgaaaaaa
    25861 ggaagatata aactgcgaaa agaaaaagag gtgtactatt tgattgagaa agaatgaatg
    25921 aagatgtcca aaaaagcaga gggaacagac taaatgaaaa aagagagaag ctgacgaaat
    25981 ggacgtgtaa actgctattt ttggtttact atctggaacg ccagcttcta tttttttatg
    26041 tttcagaaga attttattat tatagtataa cttttgaatt agtttccata acatttggag
    26101 caaggggtta aaccacgagc ttgagcttcg cttaaagtgg caggggtata cgtaccattt
    26161 ccacatttat gtgtatggta ttttgaaccg gtcggtgtga catagacagt ttgttcatta
    26221 ttttgctcag gagctgcggc ttgtgcctgc tgagaggcct gttcagctgc tgcttgctgt
    26281 cgcgcctgtt ctgcttgttg ctgtgcgatt gcttcttgtt gcgcttgttc tgcttgttgt
    26341 cgtgcaattt cttcttgctt tttccgttct tcttctgctt cttttgcttt gattgtggaa
    26401 tcaattgcag caagacggct tgtcaactct tgtttgtttt caggtagcgc ttggatagct
    26461 gctgaagcag ttgcatagtt ttcttttgta ggatttgctt cagcttgtga caaagcagat
    26521 tccgcttctg tcactttttt ttctagtgca gctttttccg ctttttgttt ctcttcttct
    26581 tttttctttt caatttgttc ttgttctttc gatgaatctg ccgtactttc ggagatcgtg
    26641 gtactgctgc tggaagcctg agctgaactt gtgctttgag tagtagacgt agtagcacca
    26701 cacccactca acaaacttcc tgcgaccaaa aacaatgcaa ctaatttttt cactaaattt
    26761 cctccttaag taaaaaacaa ccgttttcaa taaatgtcct tttcaattgt ttacttactt
    26821 gttataataa ttgtgttatg aatagtgatt gaggaaactt aatctaatcc cgttttgata
    26881 cacgggattt tttgctatag ttctgttatt aagtatgcaa taataaaata tgtacgttat
    26941 tttattatta gattattgac atttatataa taaacgatta aatgattcat atcaatagaa
    27001 tacttaggaa aaaaagagaa ataataacag gtttatgcac tattgacggt gtgacaatat
    27061 gatatttgta tccgtttttt ttcttgtatg tagtatagta aagtagatac aggaggagaa
    27121 aatatgcaga cttttttaac aaaagtttct caaaagaaaa ttaaaatgat tcatttactg
    27181 cttgaaacag aacgttggtg ttcaatagaa gaactacaaa acgaattgaa ggtatcaagt
    27241 aagtctatct tgaattatct aacagattta gaagaattgt tccaaaaata tcctgataag
    27301 gtcattttga agaatgagaa taatcggcgc ttttctatgg aaaagcagga gaacttccca
    27361 atctacatta tttatcttca tttctacaga aaatcatata attatcattt gattgaattc
    27421 atgtatcaac atcctgagaa aaatttggaa gattatgcag acgctcaata tacgagtgta
    27481 tccacagttt ttcgttatgc taagttatta gtaaagtact ttgaaatgac ggacgtcaaa
    27541 gaatagtagc cgccagatag aaggaaatta gcagttgaaa aagctgccct gcatcaagta
    27601 atacgaccag ccaaacggaa acagtgtctc atgtttttga tttggctggt cttattaccg
    27661 cagatgcaag cttttgccac acctctttct tgtcatttac agactcaact atcaatgctg
    27721 caagctttcc cttaatgctg taacaccagt aagagttgtc aagaccagca gactgactag
    27781 gtaaataccg ctcaaaaaca agattacggc agttaaacta taatgatcca tcaagaaacc
    27841 gatgacgata gaagaaaaac caccaacagc tcgtccaagg ttcataatga aattattcgc
    27901 cgtcgcgcgg atttctgttg gatacaaact actaatcact gcgccatatc caccatacat
    27961 gccattgata aagtagccga ctatcacagc ggctgctacc aaactccact ggctatgggc
    28021 taacacaagt agatagacag ataaggatga acaaattaaa aacaaagaaa aggctagttt
    28081 aggccccaat ttatccatga ttatgccaaa agtcatcatc cccaaagaca tgcctaaaat
    28141 agtactgacc atccacaatg aagacccaga aaccgaaagc cctaatcgat tttgcataat
    28201 tgaaggcagc caattcatta acccaaaata gccggcaatt tggacagtta ccatgatact
    28261 aaggccacat gtttgccaag caagatgttt tgattcaaac agtctgctaa gtttggtttt
    28321 cttttcggca gattgtacag atttgaattc ctttggttca gtcaagccgc gacgaatgaa
    28381 caagaccatc aacaccggca gtacacctac gacatacaac atcttccaac caaacgttgg
    28441 aatgatcaca gcagctaaaa tcgcagccaa agccgcaccg acctgcgcac caataccagc
    28501 aaccgaagaa gctcgtccaa tttgtttttt tgaaaaactt tcggaaatca aggacataca
    28561 cgccccgtat tctcctcccg ctcctacacc tgcgataaag cgaaagagat aaaccaagta
    28621 gatgtttgaa gcaaaataca tcaataaaga agcaatcgaa aacagaagga ccgtttgaga
    28681 aaatactttc acacgtccat atttatcagc tatgatgcca aaaaaaatac ctccaatgag
    28741 catccccaaa ttagtgatcg ttgaaatgaa acccgcttgc gtaccactaa tatgaaaaga
    28801 agtaatcatt gaagataatg aaaaagctaa aaacataata tccatattct ctaaagcaat
    28861 tcccgccgat gtcgataata ataactttcg ctgatacgtt gtcattttta tacccctttt
    28921 cctaaaattt ccctaaattg ttaaaagtat atccaaaaaa gaataaaaaa acaagacttt
    28981 tttatttgaa ataatacaca aacaaccgat atagataatc cagcttagtt ttaatagaaa
    29041 tgagtattga cttggagtac acttaaagtt gtagaataaa taaaatacat aagtaaagtg
    29101 gcaagaaatt aagagaaaga gtgatcagat gaatatcaaa caagtcagtg aagaaaaggg
    29161 catttcggcc gatacattgc gctattatga acgaatcggg ttgattccac cagttaatcg
    29221 gacaaaaggc ggaatccgtg attatacaga agaagaccta aaatgggtcg actttacgat
    29281 ctgtatgcga aatgccggat tatcgatcga gtctttgatt gaatatattc gcctatctag
    29341 cgaaggagaa gcaactgtat ttgagcggcg taagcttttg attgaagaaa gtgaactttt
    29401 gacgaaaaaa attgctgaaa tgcaagaatg tttggaacgt ttacaaggaa aaatcaagaa
    29461 atatgatcgt gtgttatcta gaaataaaat ggaatgtatc aagtaaaaaa atcaaggagc
    29521 atcgctatgg agttacgctt actaaaatat ttttggacaa ttgcagaaga aggaacaatc
    29581 tctcaagccg cagaagttct acatcttaca caaccaacct taagccgaca actgaaggag
    29641 ttagaagagg aactaggaac agaactgttt gtacgcgaaa accgcaaaat gatcttgaca
    29701 gaagcaggtt attttctaaa aaagccgagc agaagaaatt ttagatttaa cgaatcaaac
    29761 cactcaagaa ttcgagaaca gaaaaaaaca attattcagc ggccgattta cgatcggctg
    29821 tgtggaagct gataattcga atacattggc actattacta gaaaagttga tccgtgatta
    29881 tcccagcgtt caatttcata tccacagcgg aacaagtgat gatatcacgg agtgactaga
    29941 aaaaagcctg ttagatttag cgattttgct agatccagta gatacagaga aatacgaaac
    30001 gattttgtta ccaagaaagg aaaaatgggg attgctcatt ttagaaaatt ctgttttagc
    30061 aaaaaaagac gtgataacaa aagaagactt tgcgaatgta cctcttttga tctcaaagcg
    30121 tccagaaata cagcgaatgt ttgctgactg gttaggcata aaaaaggagc agttgctgat
    30181 cacaggaacg tacaatttga ttttcaatgt atttgcgcta attgagaatc aggtaggtgc
    30241 tgctttagtc atagaaggtg ctgtaagtca tctttcaaag cgagtgacat tcgttccgct
    30301 tgacccaatg attgaaacga actgcatgct agtctggaaa aagaatcgga ttttatcacc
    30361 tgtagtcaat gaattgattc accgtttcaa agaagctttt gaacagtaat aagtatctct
    30421 aatcgaagaa atttcaatac aaaagcgaga cgtatgacag tcttgctttt gtattttttc
    30481 atttttaaat caaaaaaaat aaagagattt acataacttg ttaaataagc gcttacaaac
    30541 ataagaagaa cggaaatgaa tcagctataa taaccgttgt tctggattgt aatcattaca
    30601 aagaaatgaa gattataact ttggaggtgt tcgaaatgaa agaaaaaaag caaaaattcg
    30661 ttcaaaaaac atgcccttta ttcaatggtt gggtatgatt ctgctgattg tattagcttt
    30721 attgacgatc attccttttt tatggatggt ttctgcttca ttcaaagcaa ataatgaagt
    30781 gttcacgatt ccgattcaat ggatccctaa aacttggcat ttagagaatt atctggttat
    30841 ttggtctcgt attcctttag tgacattttt taagaataca gcttttttaa gcgttgtgat
    30901 cacgttgatt cagttgttta cttctagttt tgctgcttac gggttttcta aactaaattt
    30961 taaagggcgc gatattttat ttttagcata tatcggcacg attgctgtcc cttggcagtc
    31021 ttatatgatc ccgcagttca ttatgatgag aaaagtgggt ttaacatata cgttgtggtc
    31081 gttggtgcta ttacaagcgt tcaatgcttt tggtgtgttc ttgttgaagc aatactacag
    31141 tagtatccca gattctttat gtgagagtgc gcggatcgat ggcttatcag agtggggaat
    31201 ctatcgcaag atcattttac ctcttacaaa accggcgatt gccagtttga cgatcatcac
    31261 attcgttaat acatggaacg attatatggg gccattcatt tatttgtctt ctacggaaaa
    31321 taaaacaatc cagttagggt tgaaaatgtt tattgggcta tttgatgcag agtacgcatt
    31381 aatcatggct gcctcagttg tttctgttct tcctgttgct tttatatttt tagcgatgca
    31441 aaaatatttt gtagaaggga tcgcttcatc aggaatgaag gaataggagg tgattatgaa
    31501 agagcagcgt tttgacaaaa atgtttatat ggaattcttt tattggttgt atcaatcatt
    31561 ggcaagtagc ctttgttttt ggtgtgtcaa tatcttgtat atagcagctg cgttcctttt
    31621 gtcgatagat ggaaggaatg tcttttcctt tattttttct ttacttttta ttggtccagg
    31681 ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt tttcaccagt
    31741 acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt attggctatt
    31801 tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac gtttttctta
    31861 tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt cctttagcat
    31921 caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat
    31981 agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac
    32041 aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat
    32101 cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac
    32161 tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact gtcattcttt
    32221 ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac ttttgaatga
    32281 aacaggttta gaaactgtat caattatttg tgattatttc taactaataa ttaaaaataa
    32341 agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga aatctgtagt
    32401 agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg caaaaatcga
    32461 tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc gtcacgaaca
    32521 aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag gagtagttat
    32581 cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag cgacagcaga
    32641 aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat tgaagttgac
    32701 ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca gtgcagaaat
    32761 ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg ctaagagttc
    32821 aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac ctgtccaagg
    32881 gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag atgatatccg
    32941 ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag gtatgcgagg
    33001 atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag cattgcctgt
    33061 tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc atttctttgg
    33121 tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa gtgatctagt
    33181 tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg cggaaaaaga
    33241 tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta tgcagcctga
    33301 aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt cattagagcc
    33361 tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag aattaacgga
    33421 gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag aagttattaa
    33481 cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag gtagtcatta
    33541 tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat tcagtaatgg
    33601 tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg tgcgtccaaa
    33661 tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc aggatttaga
    33721 aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg gacactacaa
    33781 tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag actttggtcc
    33841 agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag ctacaagtgt
    33901 agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg taattattga
    33961 tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac cagatcaatt
    34021 ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga cattaggagc
    34081 tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag aaaaaggaac
    34141 tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag atggcgtagc
    34201 ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac ttacccccta
    34261 tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa ctgcagatgg
    34321 agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat ttttggcagt
    34381 gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc aagaaaaacc
    34441 ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa gcaatgtcca
    34501 aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg cagcgggatt
    34561 tcacctgcat tttatcgatg atacacatac atttggcgga catgtaatgg attttgaagt
    34621 ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt ttccagttga
    34681 tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag aaatccaaca
    34741 agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg tatctcgttt
    34801 ttttgaggag aaaacctagc gtttacaaaa aaactgagct ataatcttct ccatagatca
    34861 aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat acgaaatttt
    34921 attattacag caacaaggat tattagaagc agaagataac tggttagcaa atttagcaaa
    34981 ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat attatttatt
    35041 cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca cacgtatcaa
    35101 gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga tcgttgatga
    35161 tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag aaatcgtagt
    35221 gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg gagtaacgaa
    35281 agggtatgat gaaatcgatc aagcatttct agaaaaatat gtagatcttt tattagcaaa
    35341 ttttaatata aatgcttttt catttattaa taactaaaat cgtctattga aacaaaaaag
    35401 aagagaaatc aagaataaaa agagccggaa agacagtggg catttctgtt tttcggtttt
    35461 tttatttttt tataaaatca caagtgttat tgattttcat aatcatattt taatgttatt
    35521 atcattttaa ataatgaaaa aacattaagg atggatgaaa tatgaataac gaaactatca
    35581 ttttaggaaa aaaatatatt tgccaaccta ttggcttgaa acaaaaagtg attggagaag
    35641 taatcagtaa attagaaaat tgtgttgtga tctgcgtaga cgaatatcat gacgtcgatc
    35701 gcaatgaaat attagaaaaa tgcggaaaag tagtggcaaa atatactcac gtttatgagt
    35761 tggaaacaac agaatatcta tataactata gcaacaaata tgaacatact ttagtttcat
    35821 aaagatttaa ataaagtgcc ttcaaaagcg agaagaccaa gcttttgaag gcactttatt
    35881 tagttggcag tgattgttca tgatttttga tttattcaaa aggttcgcct agagaatctg
    35941 tctctgtaac gaggcctggt ggagaaactc gataaaaacc tatactgcca gaactgtcct
    36001 attttcggat agacaaacta gtagttttaa aaagatcatc cgatccaatc atttcaaaaa
    36061 atgcaaaact gatatcagga tcatttagct caggcttgtt atcgtaaagc atttgtaaag
    36121 gttgcattta gttaggagta aacgcgaaac tatcatcatt atttgctgaa gaagatgaag
    36181 aagctaattc agagtttgtt tgaaataaag gagacgtgct gacagtttct ttaccctgtt
    36241 ttttgcagag gtagaaactt ttatatcgga agtttctacc ggagaatttt tctcatttgt
    36301 agaaattgtt gaatcgatac tattcgaaat ttgcgtatct gaaggtatgt tctttgatgc
    36361 agaagtccca caagcagtaa gtaacaataa atttgataaa ctgataaaca gaattctttt
    36421 cattatgtac acactcctta tagtatcgtt tagcatacac ctatgctcag tattaggcaa
    36481 aatcaatgca aaactatcaa gtcttttata gtatctatta gtcttagtaa tacatatatg
    36541 gagagggtga tatcccagtt caaaccagat acattggtta ccatctgtat taacgattat
    36601 gcctctaaac gcttttttta tgaaaaaatt tataagtgaa aacgtaggta tgatattatc
    36661 tagaggtaat ttttttgggt atttaaatag ttgctaggag gatagctttt ggatttttac
    36721 agtaatttta tcttaataat agcaatatta ttacttctaa atatttggtt ttttgataag
    36781 agtagaaatg cagggatagg ttttagaacc aaacgaagta cgtcttctga aaaaaagtgg
    36841 gtatattcac agactatttt ttacggaggg gttatttcaa tcagtttact ttcttcaaca
    36901 ctttattctt ttaatgttat agacgtttcc atgtcaaatt ttatatctat tattggaatc
    36961 cttatttctg caattattac acaactactt cttgtgtttg aagagaagtc aaaaaataat
    37021 taaagcaatt atgcctttta gtacaggaat tattacttct tacaaatgta tagcgaatgt
    37081 gaagcctgct gttttaattg ttctagaaaa acttttgagt gaacaattat tttatgttag
    37141 gatgaattaa tttctctaga gtttataatt cgccgtttgt ataattaagc gagacaaata
    37201 aaaaagccat ttatgttaca ctc
//
LOCUS       DAPBBV010000028        34914 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.028, whole genome shotgun sequence.
ACCESSION   DAPBBV010000028 DAPBBV010000000
VERSION     DAPBBV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.028"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..1350
                     /locus_tag="RD486_001731"
     CDS             <1..1350
                     /locus_tag="RD486_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7663464.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2815
                     /locus_tag="RD486_001732"
     CDS             1484..2815
                     /locus_tag="RD486_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7663465.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFIFSFVKLS"
     gene            complement(2802..3761)
                     /locus_tag="RD486_001733"
     CDS             complement(2802..3761)
                     /locus_tag="RD486_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7663466.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            4005..5456
                     /locus_tag="RD486_001734"
     CDS             4005..5456
                     /locus_tag="RD486_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDT7663467.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            5805..6437
                     /locus_tag="RD486_001735"
     CDS             5805..6437
                     /locus_tag="RD486_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HDT7663468.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            7025..8464
                     /locus_tag="RD486_001736"
     CDS             7025..8464
                     /locus_tag="RD486_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7663469.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            8759..8977
                     /locus_tag="RD486_001737"
                     /pseudo
     CDS             8759..8977
                     /locus_tag="RD486_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9226..9441
                     /locus_tag="RD486_001738"
     CDS             9226..9441
                     /locus_tag="RD486_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663470.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(9658..9914)
                     /locus_tag="RD486_001739"
                     /pseudo
     CDS             complement(9658..9914)
                     /locus_tag="RD486_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10101..11012)
                     /locus_tag="RD486_001740"
     CDS             complement(10101..11012)
                     /locus_tag="RD486_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7663471.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(11031..12035)
                     /locus_tag="RD486_001741"
     CDS             complement(11031..12035)
                     /locus_tag="RD486_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDT7663472.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(12032..14155)
                     /locus_tag="RD486_001742"
     CDS             complement(12032..14155)
                     /locus_tag="RD486_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7663473.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(14160..16607)
                     /locus_tag="RD486_001743"
     CDS             complement(14160..16607)
                     /locus_tag="RD486_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7663474.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(16594..16983)
                     /locus_tag="RD486_001744"
     CDS             complement(16594..16983)
                     /locus_tag="RD486_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7663475.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(17043..17546)
                     /locus_tag="RD486_001745"
     CDS             complement(17043..17546)
                     /locus_tag="RD486_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDT7663476.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(17559..17783)
                     /locus_tag="RD486_001746"
     CDS             complement(17559..17783)
                     /locus_tag="RD486_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663477.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(17887..19797)
                     /gene="ltrA"
                     /locus_tag="RD486_001747"
     CDS             complement(17887..19797)
                     /gene="ltrA"
                     /locus_tag="RD486_001747"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDT7663478.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(20543..20680)
                     /locus_tag="RD486_001748"
     CDS             complement(20543..20680)
                     /locus_tag="RD486_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDT7663479.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(20677..21861)
                     /locus_tag="RD486_001749"
     CDS             complement(20677..21861)
                     /locus_tag="RD486_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7663480.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(22120..22410)
                     /locus_tag="RD486_001750"
     CDS             complement(22120..22410)
                     /locus_tag="RD486_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663481.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(22400..23542)
                     /gene="dcm"
                     /locus_tag="RD486_001751"
                     /pseudo
     CDS             complement(22400..23542)
                     /gene="dcm"
                     /locus_tag="RD486_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(23618..23782)
                     /locus_tag="RD486_001752"
     CDS             complement(23618..23782)
                     /locus_tag="RD486_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663482.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(23775..24449)
                     /locus_tag="RD486_001753"
     CDS             complement(23775..24449)
                     /locus_tag="RD486_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7663483.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(24527..25867)
                     /locus_tag="RD486_001754"
     CDS             complement(24527..25867)
                     /locus_tag="RD486_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HDT7663484.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(25950..26285)
                     /locus_tag="RD486_001755"
     CDS             complement(25950..26285)
                     /locus_tag="RD486_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HDT7663485.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(26295..26669)
                     /locus_tag="RD486_001756"
     CDS             complement(26295..26669)
                     /locus_tag="RD486_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7663486.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(26682..26996)
                     /locus_tag="RD486_001757"
     CDS             complement(26682..26996)
                     /locus_tag="RD486_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7663487.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(27109..30336)
                     /gene="fss3"
                     /locus_tag="RD486_001758"
     CDS             complement(27109..30336)
                     /gene="fss3"
                     /locus_tag="RD486_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HDT7663488.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            31124..31447
                     /locus_tag="RD486_001759"
     CDS             31124..31447
                     /locus_tag="RD486_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663489.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            31611..32528
                     /locus_tag="RD486_001760"
     CDS             31611..32528
                     /locus_tag="RD486_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7663490.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            32521..33303
                     /locus_tag="RD486_001761"
     CDS             32521..33303
                     /locus_tag="RD486_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663491.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            33304..33984
                     /locus_tag="RD486_001762"
     CDS             33304..33984
                     /locus_tag="RD486_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7663492.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            33977..34873
                     /locus_tag="RD486_001763"
     CDS             33977..34873
                     /locus_tag="RD486_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7663493.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
BASE COUNT        10514 a         6893 c         6330 g        11177 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttttcgttt gtcaaattaa gttagacaaa
     2821 tcatcttttg tgacgtaact caaaaatact tccattggtg tccgatagtg taatgatttt
     2881 ctaggaatat gatttcgttt cgatgccacc gattggataa aggtttcaga tacaccatta
     2941 aaatccatag ctttatacaa accatcttta cgtaataagc catttgaatg ttcattcaat
     3001 cctcgttgag aaggtgttcc tggatccgca aaataaattg aaatatcgtt ggtattacta
     3061 atctttttcc aatttgagaa ttcttttcca caatcaaatg tgatggattt aaataagttt
     3121 tttgggacac aacgaaacca ttgattcagc ctattttcaa tgtctttagc ctgtctgcct
     3181 tcgggtttca aggtaatgat gactttagat agccgttcaa ctaatgtgat gaccgcgctt
     3241 ttatgttttc cacccacgat agtgtcacct tccaggtgac caaattcatg atcaaactgg
     3301 gtatagtctg tctttctgtc tcggattgac cggcgaaacc cttgttttcc tcttttttct
     3361 ttatgaccgt ttggttttct ttttcccttc attggtaaat cgtgagtgtc aaaggtttta
     3421 tctttaaaca ttcgatacag tgtgcgtacc gaacaagcaa taggaaactc tgctcgacca
     3481 ataaggacat caggagccca cccttgaaca accttttttt gaatgtattc ctgttgctca
     3541 tcaggtaaaa caatcggatg tcttccgcag ttacgtttgt ttttcttata ttgtttatag
     3601 tagctcattg cgcttccacc agatttaaga aaacgataga ccttataaat agtttgtcga
     3661 gaacgttgta acagattggc tacttttgaa acaggttgtg attgattgaa ataagcttct
     3721 atcattacga gttcagttgg tgtaagatgg ttataggtca tttgtactca ctccttataa
     3781 ttctttcgtc ggaactattt tgagtgtagc acaaatgact ttttttagtt gtctagctta
     3841 attttacaat cggcgtttta aaggcagtaa caggattaaa cattgaaaca taatcgttac
     3901 taaatgaaat caagaaatat actgtattac tcaattcatt gaaaatattt atcataattt
     3961 ttaatagaaa acactattaa agagaaaaaa gagaggtaaa tcaaatgaaa aaatctttaa
     4021 aacttgcatc agcagttata ttaatgtccc aactccttat agcaacacct ttccatgtgt
     4081 tggcaagcga aaattcaaca tacaaaattg caaaagaaag aaccgagacg actgaaatga
     4141 gtaattccga tgtaacagca gagagtagtg aacttttgac aacttcatca agtgaaagta
     4201 gtacgacttc aaatgccgag tcttcaacaa cttcatcaag tgaaagtagt acgacttcaa
     4261 atgccgagtc ttcaacaact tcatcaagtg aaagtagtac gacttcaaat gccgagtctt
     4321 caacaacttc gtcaagtgaa agtagtacga tttcaagtac cgaatcttca acaacttcaa
     4381 gtagtacaag tgaaataact tcttcgaaag tgacaaaacc aaaccatata gaatcttcaa
     4441 aaaaggaagc gccaaaaacg gaaggacaaa caaaaacttt ttcgacacca cagcaaatag
     4501 aatcaacaga atctttccaa tcacaaccaa tactatctgg taatgaagaa attcattttg
     4561 acaaaaatga atctgtagaa aattttatta tgaaaattgg tgagtctgcg agaaaaattg
     4621 gtcagaaata tgatttatat gcttctgtta tgattgcaca agcgatctta gaatctgcca
     4681 gtggtcaaag ccagttagct caggcaccga attacaattt atttgggata aaaggaactt
     4741 ataatggaaa ctttgtcatt atggtaacaa acgaagattt gggtaatgga acgctttata
     4801 cgacccaatc aaaatttaga gtgtatgaaa actatgagga aagctttgaa gattatgcca
     4861 aattattaac taagggaatt agtggaaata aagattttta tgcaggagca ttaaaagcta
     4921 atagtaaaac atatcgagaa gcaactaaat tccttacagg acggtatgca acagatacac
     4981 aatactattt gaagctaaat gaattaatta aaacctacga tttaaccaac tatgataaag
     5041 aagttaaagg tccacaaatg agtaagactg gataccaagt gcctattcat aattattcaa
     5101 taaccagttt gtttggaaat cgtggaaatg aatttcaccg aggacttgat atggcagcta
     5161 cacagggtga gccgattcat gcagttaaag ctggtaaggt tgttaaagca gagtttcact
     5221 actcttgggg aaattacgtg gtgatacaac acgaagatgg atcaaccgcg ttatatgctc
     5281 accagcaaca atacctagta aaaactggag ataatgtttt gcaaggacaa ataattggct
     5341 atgtaggaag tactgggaat agtactggcc cacaccttca tttggaaatt tgcaaagata
     5401 gtagtctttc tcagagcatg ttagttgatc cgaaaacctt attattcgga gactaaaaaa
     5461 ggtaatcaat ctgacaaagt aacaagaaaa tggttggatt cttagacctt tgatcaggat
     5521 attgagactg gaattgatat ctcgattacg atgggtttga caaataaaac aagtccatta
     5581 tcgaatatcg agtgtattat tgccgtcttt atgctcatat tttgagcagg tttcactaga
     5641 tgaaaacaat ttatctatct tgaggatttc gtgtacgtat cgttcagtct tgtattgtaa
     5701 attagtcata aaatcagact aagaaaaatt ggaaatattt ttttctgatt tattaaaagt
     5761 taattgaaat tatatggtac ttctttcttg ggagggtagg tgcagtgaag gaaagatatg
     5821 gtcaccttac tgttgttgag gagattactc ataatggata taaaaaatat cgttgcctat
     5881 gtgactgtgg gaatgaaacg attgtatatc gatcaaactt actaacaggt agaaccaaaa
     5941 gttgtggatg tggaaattat aaaaataggc ataaatataa aaatttgaca aataaaactt
     6001 ttggtaagtt agttgcaatc aagccaacta aactgcgaag tgaaggaact gttgtttggg
     6061 aatgtcaatg tctgtgtggg agaaaaaagt tagtatcggc aaagcgactt ctaaaaggtg
     6121 atgtaaaaag ctgtggatgt ttgaaatcaa aaaagcatca cattgaaaat aaaaaattcg
     6181 gattacttac tgcaaagtat cctttggaca ataactgttc atggaaaaca aaatgggttt
     6241 gtcattgtga gtgtggcagt atgtgtgaga taagttatag taacttattt tttggacata
     6301 ctcaaagttg tggatgttta aaaaggcaag aaacaaggac atgtgttgaa gggacagtaa
     6361 tagagtgtct aacgtcaaaa ttaccgaaaa ataatacaag tggtgttaag ggagtttatc
     6421 gttctaaaga gaaatagatt gcgtatataa ctttaaaaaa aaagaggtac tatttaggat
     6481 cgtatgattc tattaagagt gcagctcaag ctagaaaaga tgctgaaaat aaattgtttc
     6541 aacctttgat tgacaaatat cgaggtaatc attaattatt gtggataata attaacagtg
     6601 atatataaac atctataata tattattcat actattgata tttagtataa tcctatggaa
     6661 ttgaatatca tagcaatgta tttgaaaagc aaattggaaa acaaataggt gcaacaccat
     6721 aaatatgaaa aaattgggaa aaagtagaat ggaaatttgc ttacgtctca cgagatagct
     6781 cacactatta atctgaagaa caatgaagtc gacttttaga aattgctaga agaaagtaaa
     6841 gcgaattatc actagttact atagagtaag ttcaaataaa gcatctccaa cttacatggt
     6901 tacatgagga tatcaaatcg aaattactca agcttcctat ggctagagtc gcgagaagtt
     6961 gttgggcagt agacataggt tatattgttc ttagctacac gatcattaga aaggaaatcc
     7021 tattatgtat agttatcaag aagatgcaaa agtccaaaaa aatcgctggt ggattttgat
     7081 tgctatatct atgtttacct tcatgtccac attggatggc agtattgtca atattgcact
     7141 acctaccatc tcagatgata tgggcatacc aatgaatcaa gcggaatggg tagtgtccgt
     7201 ttatctgatg attgtctgtt cttgtttgtt gctgtttggt aaaattggcg atagccgtgg
     7261 gaaaatcaaa gtatttcgga ttggtacgct gatctttgtc ttgggatcgc tgttgtgtgg
     7321 gttcaatcat tcgctaggta ttttattgtt cgcacgggtg gtacaagcca ttggtgctag
     7381 tatgactatg gctacaaatg ccggaatcat cacggaagtc tttcccatac atgaacgtgg
     7441 tcgggcattg ggagcaatag gtgcgtttgt ttcattaggc tcgattgctg gaccaggtct
     7501 tggcggcttg attttgtccc aattttcttg ggcgtacatt ttttggatca atgtaccggt
     7561 gggaatcgta acgatgttga ttgctgaaaa attcttacca aaagatatca ccatgagcgg
     7621 ccatacaatc gatggagggg gctttgctgc cattgcggct acgattatca gcttttttgg
     7681 agcaatcttt ttggggcaag aaagtggctt tttccatcca gtcccccttg tactgttcgt
     7741 aatttcagtg attgcctttg tcagcttttt aaaagttgaa aagaaagcag cctctccatt
     7801 gatttctttc ggtattttta agaacaagat ttttaccatg agcttgatta cagccttgtt
     7861 gattttttct tccaacttct ttgtcaatgt agtgattcct ttttatctgc aaaatgctcg
     7921 cgggttgagt cctagctatg ctgggctgtt gatgatggtc tttcctttga tgatggtcgt
     7981 cggggcgcct ttaagcggct acctgaccga ccgggttggc ccggagattt tggtattagt
     8041 aggcttgggc ttattgtcgg taacccaggt catgtatatg tttttgtcag tggactctcc
     8101 tttgtggcta tacattgtcg ctactgccat catgggtgcc ggcaatgcct tgttccagtc
     8161 ccccaataat acgatggtta tgagctcggt cactatcgaa aacttgggac tggcaggctc
     8221 gatgaattcc tttgcccgaa atttggggat ggtcagcggg atttcgcttt ctacgacggt
     8281 cttatatcaa gcgatgtctg ctaagatggg ccagcaagta actaactata tcgcaaatcg
     8341 gccggatgtc tttttatatg gaatgaagat taccttttta ggcagctttg ttttgtgttt
     8401 tgttgccttt ttcctgacta tctggcgtat caaaaaacaa ggaggtattc agaaaaatgt
     8461 ctgaaaaaac cactgttgaa gaatttttgg aggcctgcgt atgggtgagt gggatttcca
     8521 tggatgatgg aagatgaagt gaacttctaa aagccgaaaa actcaagtat tatcttcaaa
     8581 atactagtgc tcaatgagat gcttgatttg atcacaagaa gactgcgaaa gccgctggca
     8641 accgcaagct aggtatccca ccgatggact acgttttaga ggctactggt tatgaatacg
     8701 gagccaacgc tctcatctgc ataagaatac atcacccaga ttatgtaaag attttcgata
     8761 cttctgtcaa aaaatcatta agatagataa atgatttccg tctagtcaaa ttggttcaga
     8821 atgtagacac acagatggta agaagtcact cacaattcga gaatggactt gtcctatttg
     8881 ccgtatacat cataatcgaa acgtcaacga tagtatcaat attttgacca agggctatga
     8941 atacaagcat tgccttagaa aacatcaaga accttaggaa caacggggat agcttggtta
     9001 ataagagata ccgctgttta ggcttgcaag tatactcttt tatcaagaat tccgtggctt
     9061 tagtcatgag aggcttaata ctatgaaaat tttctttagc atttttgatt taggttcctt
     9121 ttctaattat aataagatga ccactacagt aacctactga aatatataaa cagccactgt
     9181 agtaccattt tcaaagtagt ctatgagagg agaatcttca ttcttatgaa cgctggaatt
     9241 gcggatatga atttaataaa aaaaaccctt aatgatttta cttccaattc aatatcaaaa
     9301 ggtactggta tcaatttaag cacaataaaa aagctgaaaa gtggtgaaag atcagtggaa
     9361 aagctgaatc ttttagatgc tataaaaata acggaatttg ctatgaaaaa tggaaaagct
     9421 gagattgaaa tatggagata attatcgtct agtgaattac ttgccactta gctgaattta
     9481 acgatccttg gtgcttgaag ggggagattc ttgggaatag agcatacttg caagcctatg
     9541 tctttactaa caacgatatc tcttattaac caagctatcc ccgtagttct aaggctttta
     9601 cttttatcta agcaataatc gtattcaaag gaaatttttg acccttagaa agtctcattt
     9661 tatcagacgt gagcttaggc attgctgaat tttgttaatt cggttttagg ttgtgctttg
     9721 agcataatat gaaagtattc tttatcacga tttcattcat ctaaggtaat gtgatgtgat
     9781 tctgaaattc tttcaaaggc agtttttgca taagctgaca ttacatcatc aatgacatgt
     9841 ttacaatgtt tcactactaa aataaggggg taaccaagaa gaaaaactga atgattattt
     9901 gtatctaatt ccatggtata tcaaccattt cctatataga ctgattatga catggattaa
     9961 aataaaaagg cactatgtct taattgtcgg ttttcgagtt accgaatggc attcatcacc
    10021 cacctataga ggatgggcga cttctgcctg aaataagtta cactacttat aacttctaat
    10081 aaaattagat tgagtcatta ttatttaaca tcaacgattt tccagtttcc atttttttgt
    10141 aatactaatt tgtactgaaa gtagctagtg gtttttgata cattatcaag gtattttatc
    10201 tttgtactca ctagaaaatt ttttccgttt tgtagataaa ctggattctc taactccgaa
    10261 aactttaagt caatattgat tggtcgcatc gcaccatttt caacataata ctccaattct
    10321 ttttcagaag ctgatggata aagtttaaaa aatgtttcta aaaaatcggt gatttcttcc
    10381 gttgttttgg catcaatttc tgaatcgttt tctacttgtt ttgcttcata ttttgccttg
    10441 tctggctttc caatcattgt tggcaaacta gttactaaat gattcctgtt ttcatcttca
    10501 aagattgtca ctcgatatgc agaagaaatt gattgcgtct tttttccctc tgtaatatgt
    10561 tgctccacta aaaatgaaac gacaaattct tccgagtgtt tttcaacatc tagaattttt
    10621 acagattgaa cttcggaact cgtgggaata tctgctcgaa ccatatcttg gattaaagcg
    10681 agaccgtttt ctgtaaggta ctgttcgaga ttactcattc tcttttcaat tgcttctttg
    10741 ttatttttcc atgaaaaata ttctttcgca aaatcctctg taaaactttc aacgccagaa
    10801 gtattcacta ccttctcttt tataaccact ttttcatgag ttgtatgttg atcaatggcg
    10861 gtgaaatttt tataaacgcc aaaagcaaga ctacaagaca ataaaagcca aagggcaagc
    10921 accatttttc gatgcttacc cacggataca actcgttctt ttttcttttt tgggctcttt
    10981 tccttttgat tccgttcaat ttttatcttc attctttttc ctcttttctc ttatttgtat
    11041 cggccagctc cgataagatg ctgccgccaa tagttttccg ttagattcgt ccaccccact
    11101 ggatctcctg catgaaacat gcgattctcc cctgcgtaaa tgcccacatg ggtcacataa
    11161 gtaccggcat cataggttga atgaaagaaa actaaatcac ctggtttggc atcttttaga
    11221 tcaatatgag tcatggcatc atattgatcc tgagccaccc gaggaagttt caggtcaact
    11281 ttggcataac accattgggt caagccacta caatcaaacc ccgtttctgg acttgagcca
    11341 ccaaacacat aggccgttcc ttcatactta aatgcctcat caaaaatttc ttggactatt
    11401 ttgtcatcaa actgagttgt agttaggtat tgcttcacta ataaacagta aaacatattg
    11461 ccataattat accgccaccc accattttcc ttaatcgcga ttgggttggg gtaatcgact
    11521 ttttgaccac ctgatttttc ctttgaaaaa gattcagcta aagcaaaact atgcttcttc
    11581 ccgtttttcc cgacatgatc tagatacccg ccaccatagt tataggcctg aataatacta
    11641 tcttgatcac accctagttc tttggaacgc ttaaccaaag acgcaaaata gagacagcct
    11701 tgtttgatgg atgcctcggt acttaatgaa ttaggtggta atccggctga ctcagaactt
    11761 tgcataacgt cttccattgt gccaccagat tccacttgaa taatcgccaa aagaattgga
    11821 atatactctg ttatatccga ttctttggca tacttttcca ccattgcacg gtgtttcaat
    11881 acttcttctg agacactagt tccgccagga gaagtgccag aactaccatt tccctcactg
    11941 tcttcaccaa acaacaaacc cacacacatc aaaataccca taaaagagat ggtcagaaaa
    12001 gttaatgaaa taacacccac tttcttcaag ttcatttttt ctcacctgac cttgattttg
    12061 gacgatggtt cattcttttt tgtacttttt gattggtctg ctttggcaga gtggacctct
    12121 gtttcacttg ttggaaagaa tttttcttac ttgctgattg gcttttccct tttgaaatga
    12181 tttcttgact agttagtttt cgtttgattt cgggattcag atttgctctc acaatccgct
    12241 ttggtgcttc ttttttcagc atcatatctt tctgaggttg agctgcttta tctattggaa
    12301 tattcgccct tctttttccc tgacgatttg ttgcttcact cagtatcttg cgtttttcgt
    12361 ccattttcgc atttcttcgt tgtcgttgtt tttctcgcaa atccactcga tccgcttttt
    12421 cttggaacag tccgcgcttg aattcttctg gtgctttttt cgacttttcg attcctttat
    12481 ggagattgta tttcaaattc gttggcgtat tccttacctg atcctttact tgtttagtct
    12541 tatctttcac caaagcttgg gtatccaaaa ctttgccgat ttttctccca gccaaattca
    12601 ttcgggattg tttcttatta tttgaaactg gattctcctt agttaagtca gatagtattt
    12661 cgtgatcgtt cggtaatcgt gaattctttc gtagagaaga accggatggc ttaaatttgg
    12721 attttgattg ttcctttgcc aacttatttc cgactgctgc accaccacca aaagccaaag
    12781 ctcgtcccac atttcgattg agttgccgca attttcgatt cattaacatt tgcggttttc
    12841 gcatgacgcg tcttcccatt gactggctat cattactctg gaggttgaac atactcataa
    12901 tgtcgcccaa tttgaaatag ataccggcaa aggtcacaat ttgcagaaaa gcaaccatga
    12961 aaaatggata ggttgccgaa atattgaaaa acatcgtgga gatgctaaat gcagtcgtaa
    13021 tcaccaaagt aacacccgct cgcatcataa tcgtattgaa taaacgaata atcgccttct
    13081 ttcctaaact ttcataagtc ggcaacatgg acaataagaa actaattggc agaaacatcg
    13141 caaagataat gaagagaatt tgcgagaaca acataatccc tgttagaaga aaaacaaaga
    13201 aggaaatgcc aatattgaac aataccaaaa agaccacggt ccctaaacgg ttcatggtct
    13261 tggtaatact gagattcgca ttgtcattgt cttcaatctc tgccttgacc gcttcttccc
    13321 gatctttgcc tttgttttca tctggactca cagatagaat cttgttgacc cggtcttcac
    13381 caatttcttc tatgttggaa tcatcaaatt gcagtagtaa ccaaggttgt tggacttgaa
    13441 tcgaaaacaa actatcccga atcaaatcca cactatcttt tccttggctt tctgaattgg
    13501 gtacaacgat ctcggttcca agggtaaggg ccgcttcact aacatctgag ctaaagtcat
    13561 tgatttttgt gatataggta ggcgcataag caatgaacga acccgatagt agaaaaatca
    13621 tcacaaaatt aatcacggct cgaactgctt tcgtggtttc tcgttttaat aatccggtat
    13681 acgccacata cacccccaga gctaaaatca tcaataatag aaacccaaaa taaaatccgg
    13741 aggtctggag tccattttca gtaataccag ccaatgtttg gatattcttt ccaatacttt
    13801 cagccgtatc cgaaatgaaa tctaatttgt aagcctcttg aaccacataa cccgtggcgt
    13861 tcgacaaata caaactcacc gtccaaatga aattagtaat ggcataaaga ccatacatca
    13921 cgcttttccc taagccatca ccccaattcc aaggcaacca atcccaagag ctatccacaa
    13981 agaaatctag ttgatagttg ttcagtgaat atttggaata tagatttcct gcttcaactg
    14041 tatcatcaac tagccctgtc gcctcggcta ccgtaccaac taaactcaat agaactatca
    14101 gagtgagtat gctaataaaa acgattccca caatccgaaa aagtttcttt ttcatcccct
    14161 cactccattc tctcttgaac aggtggacgg gtatcaaagg catggaagag ttcttcaaag
    14221 actggatgta cctgaaccac gcctacccga ccatacaaat cctgcatcaa gcattggcca
    14281 ttttccaaat ctcgtaggcg tttttgattg ctttcatctt ctcgatccaa gccaaagaat
    14341 tccaaggttt tcttgatttc atgaatatcg gtactgcgaa acgcaaactt caacccgata
    14401 ttattcttca agcgttcatc cagtaaatca tcactatttt gcgtgacaaa gtaaaccccg
    14461 gcattcatag cccgcccagc acgaacgagc ttattcgata atgttttccc ttgcgctact
    14521 tgaagaaaac tccacgcctc atctaagtct acaattttga agatttctcg attactatgg
    14581 ataaagtcca aggcaaaagt ggaaatgacg attagcatgg aaacactaag caattccatg
    14641 gtggtatatt cttcaaaagt ggtttctgca tctggtaaaa ccaaatccgc tacttgaatg
    14701 atatttaact gcctatctaa actaatcgac tgggtaatcg aaccatctga gaaaagcaaa
    14761 tgggcaaaat cataatcggt aaaggactcg atgtgatccg cgatattttc cgcaactggt
    14821 gagccttctt ttcgaagctc attaattact tgtaataatc cccgttgatt gctttgggta
    14881 accgtccgaa tggccttacg caacactgga aacttctccc catctcgact agaaattcct
    14941 gttaaaaagg tcagaatatc aattgctaga ctttcagaat ccttcttttt ctccataatc
    15001 acataaggat caagtaatcc ttgatttttt ggcttactag ttaagttgag aatattgatt
    15061 tcatccgcaa tttctggcaa ggtttctttc cagccacccc gttccccttt tggatcgaca
    15121 atcacagctt gtccaccaaa aaggacggcg taataaacta agagattgtt actaaaggac
    15181 tttccgccac cgagtgaacc gaggaatgcc gctgctagcg cattggtaac tgaatccttg
    15241 accccttgtg aggccaatgc cggtttcagg taaacattgc gccccgtatc tacgttataa
    15301 ccaaagtaaa tgccttccaa ctcccctaac atctgagtgg cgccaaaacc aagtccggcg
    15361 agaaaatcag acgtaacata ctggatataa tcattcatgt atcgcttact agaaggtaag
    15421 aattcttcat gtagccccat catatcgcca aaaggccgga ctagttttac attggtatca
    15481 tcataaaaat ctagcacttc atcacaccgg cgctttagtt catctactga ttcggcactt
    15541 actcgaacca catagctcag tttgtacatg gattctttgg actgatccaa ggtagtttcc
    15601 aattcatcta cggaatccaa tgcatctaag acattggaat ttgtttcatt gtcagattga
    15661 taggcatggt tgtccaagtc ttttaattcc tttttcttat tgcgaacggt agcaagtgcc
    15721 tttttgttcg tcacaatctc cacattcata ctagtgtcaa ttgggaatgt aaattgttgt
    15781 tgctggtaat agaaaagttc tgaggaggga aactccattt cccccacaat tgtattaatt
    15841 gttaagtacg ctacatatga ttcatgattc tcatgttcca tgcataagta ccggggcttt
    15901 tcttcaatca aacaacgact gggacgtaat aagtcgtaac gtttcaccaa agtttccgac
    15961 ttcagctttt tctttggtag ctgaaattca tattcttcaa atggtgtacc cttttcgcca
    16021 tagatatgtt caatcaaata catcagatca ctcggtgtga ctcgtctgac tttaaatctt
    16081 cgagccaatt tactttccat tagtttttca agcttggtat atcggcgaat ttcttcattg
    16141 gataaggaaa caaaatcgcc catcaaatga tgattcactc catagacaaa ttcttgaaag
    16201 ccggagaaga aagatttctt gagattcttt agattgacct cttcatctgt cgcaatcagt
    16261 ttgaagccaa taaaaaagcg ataatcaatc tgactatcgc caatcatgga tactaatgcc
    16321 tctgtctgta aatcaattcg ttgtttcgct acttctgtta atcgcccggt aatttccttt
    16381 tttgatcgtt cttgcgtggc acgaatacta ctttctgtgg caatttgtaa ggcatgaatc
    16441 ttgccttcac gattttgcgc aatcaattga cgaaagttat cgtggacttg atatttctgt
    16501 tcaggtgaca aaaaggagta attgtaaggt attaactcat agtaggcaaa acattctccc
    16561 tcttgattaa agacaagatt attttcaata tacttaatcg ggtacatagt tcacactcct
    16621 taccagagta atgggttcgt cccatcgttt cttctgttct ttgactttct ttcctgcgaa
    16681 agtgacctta aatcgtaagt gatagctaat aaaagatcgt aaaaatccca atggtttctt
    16741 accgtcaaac gttttttgcg acatgaacca agtaactgcc accggtatac ctaagtattt
    16801 taaaaaggcc ccctctatca tagatagtgg aggcacatgg gcaaatacga tgacaaacag
    16861 caaggataaa acaaaccaag ccatctggtt aaaagtcaca ggaaaaggca gttgaaagtc
    16921 attaattgca taaatgacct tttcaactgc ccaaatactg gtgtagcttt ttattttctt
    16981 catcaaatca ttcctttaaa aagaaggata gtttagaaat caactaccct tcaataattt
    17041 tgttaatatg gatactcaaa aacacctcga ctcgttacca aataattgcc tccaatctcc
    17101 aagtctctac cacacgcatc aaaatcaata tacgtcttca agtgttctgg tacttctcca
    17161 aaatcaccag cttctacaat caagaaatat gctacatcac tcatatcatc gcaatctgga
    17221 taatagataa tatcatccac atgctctacc atctcctcaa aagaattgaa gaaagcatgt
    17281 tgaatctcag aagcaacttc accaactggc gttccttcaa gttcctccgc taagccacac
    17341 aaccgattaa tttcctcaat tggcgtatac tcatcaatct caaagggaag ttcataatca
    17401 tgaattgcat attcctcgta ttcgtcattt aacccaattc gttctttcac ttcatcaaaa
    17461 tcgacaggtg gggtaaacca cgcccccacc aattcacctt cgttatattt cccgaggttc
    17521 gcaatataaa cacgcatctg ttccatcgtg cttccccctt acgcaccgac aattcggtta
    17581 aacaaactga gtaagacatc cttcacccca gaagcattaa agaccaatcc gaccgcaatc
    17641 aaagcaatca ccaaaaagcc aatcagtttg gaaaactccc gcttaaatcc taaaaacaaa
    17701 ccaatgacca caattgccag taagactaag gattgggcat tggttaaaaa ccattgatat
    17761 atggataggt aagttcctga tattataaat atctcaaact tttcccccca ttcacacgga
    17821 gcgtgcgact ttcaccgcac tccgcgttcc atcgtgttta tattgaaaag tatttatgta
    17881 gtagacctat atcaagttta attcttgatt gccagctaat actctatatt tatttagtct
    17941 tatgagctgg actttattta gcttcaatag agctatatat ttttgtattg tttcttctgt
    18001 tttagcgtgt attagacggt gtaccgcctc ttttaccaaa ataagatttt tataatcgtc
    18061 atttccacca gctccagttg gtacaatatg atgacaatgt atttcattag cttgttgaaa
    18121 ttcttccaga gttatagcac attttccatg ttgagcagaa aatagcgaaa ttcgattgtc
    18181 tgcgtattct attgtgcgat tttccaaaga taatttcatt aactggtaca tcagtaattt
    18241 atcaacactt agattggtgt ggataaattt tcttccctct agagtgtagc aattcgctaa
    18301 atacaccttt gccattggtt ttctgtgttg gatatatcca acagggaaaa taggttcgcc
    18361 ctcgccagca acataccgaa gcattttaga tttaccatat cttgttgcct cctttgtcgt
    18421 aagttgtctg cctgtttttc tcaatctgcc ccttttgttt gtacctaatc tgttagtgaa
    18481 gatagccatt acagctctat tcagtttcat acaatccaga tttacattcg ttgcaatctg
    18541 ataataattt tgcataccta ataccattga attataaagt cttgtttctt ctaattccgt
    18601 tttccctttt gagggagaag caattttctt tgcctgtgat accagcttgt ctttttggtt
    18661 tttgaattgt ttatcactta tatgtgattt aacaactaac ttctttcttc tcggtatcat
    18721 tttaatcttg aaaccaagaa agtcggagta tctttttcta acatttacaa ttcttgtttt
    18781 ttcttgtgat acttccaatt ttaatcgttg ttcaatccat tgagtgattg ctattttggc
    18841 tttttcagca ctttccttgt agcggcagaa aactctaaaa tcatctgcat aacgaaccat
    18901 atacatttcc tttaactttg ttttcttcat ttctttgtaa gcgttgcttt tacatgggct
    18961 accgctttta ttgatatgaa ccacatagtt ttttgtaaca ggattttcct gccattggct
    19021 ttctacccaa tggtctaact cattaagaac aatgtttgct agtagtgggg atattattcc
    19081 cccttgcgga gttcctttct ctggatatgt tattgtaccg ttagtcattt tgattggagc
    19141 ttttaatatc ctttttaaaa tgaatatcaa gtgcttgtcc cgtattccca tagcccatat
    19201 ctgttttatc agcttggaat ggttcacgtt gtcaaagaaa cccttaatat caaattcaat
    19261 cacataatgt agctggctga tttgtaggcg gttataggtt gcttttattg cattttcaac
    19321 tgacctatta ggtctaaaac catagctgtt ttcactaaat ttagcttcgc agattggttc
    19381 taatacttgt tttatacatt gttgtataag cctgtcccac atacaaggaa tacctagagg
    19441 tctggtttta ccatttggtt ttggtatttc ttttcgcctc actggcttag gtcgataccc
    19501 atgtggactg cctgcaacaa tgtatcttac ttttttgaca actgtttctg ctggcaattt
    19561 gccaatatct ttaattattg taccgtctgt tcctgctgtt ttactgcctg catttgcttt
    19621 gatatttcga tatgccagta atatattttc tctcgatagg ataatatcca taagatgagt
    19681 gaaaatatct ccattcttac ttttggcata taaatcatca aaggtgtttt gcatttcgta
    19741 atattcagcg tgtcttaaat cttctacaca caatgtttca tttttatttt taggcataag
    19801 gcttcactcc tttacttgaa attgagtgag cttttttatc ttactcgtaa tccttattga
    19861 aacaacataa tacttttcta atatatacac gacttgaggg cattcctcca ttctcattac
    19921 aagaatttct taggttcgcc ctctgctttt cagcattagt tcaactgctt attgttcttc
    19981 gtcagtttat tctcttgatg agaacccaat acctttcctc gttccgataa tcttatctat
    20041 acatatatat ccttaggtca ctagctataa gcctgctggc ttgataccgc ctgtaacgtt
    20101 atatggcatt tcataaccta tattcttact ttgccacacc agctacgatt tctcgtacct
    20161 ttgcatttct acaaagttca aatttagacc cgtacattcg ctgtttcgtc agttccttat
    20221 agaacattct aaccatagat attttataga cccccgacct gttggatacg ctacccacct
    20281 ctggatagtt ttcgatagaa gatatatgtt catcaactat tacggtatct ttcagccgtc
    20341 tttaccgagc ttcaaacatt ctgagtttcc tcatacaatg cttgtcggag gctcagggca
    20401 ggcgtttcag agcgttactt catcattcca cctgtcagat tatcagttct cctaataacc
    20461 aaactttttc gttcttttat tagtgcctta gcttttcact aaggaacgag tcgcacataa
    20521 attttgtccg aaattcatct tgtcactttc ctttcttttc cattgctcga tccgctgctg
    20581 cacttgcatt catcaagcac atcacagtaa caccaagcat actgccacca aataccaaaa
    20641 aaatatcttt tacaattccc atgacgattc ctcttttcat ataatcaaat tttcaattgc
    20701 catactttgt tgctccaaaa tctttttatg tcggtctgat aagcgtgcat tctgtaccat
    20761 atcctggata taggttgtcc gattcaatcg atccaactcc ttagccattt tccacgtagg
    20821 ggcgacttgt cggcctagcc aattcaaggt tcgttcaatg gtatacggtt ttggctcgga
    20881 agttaattga atctctttcc gattccgtcc aataaaacgc ccccattgtt cattcaaggg
    20941 ccagttggtt cgccttttac cttctacttt atccgcaaat cgcaagtaac gattgataat
    21001 ggaaaacgtg gtgctctcaa tgctacgacc ttttaacaaa tcttgaatcg catgaaaagc
    21061 acggtcattt ttcagtcgaa tctcaaaacg atttttcgtc tcagtttggt ctaatggaat
    21121 ccctaacttg atatattgtt catagtcttt ttcatacaaa cagaaataaa cctcactctt
    21181 gagactgccg atatataagg tattgcccat gccgtccttt tcatcagcct ttaaaagttc
    21241 cccggaacga taacttttaa aggtacgaaa caaggagata cattcttcct tctgacattt
    21301 tttcgttagc tcaggtatat ccaatagccc cactcgatca ttgattgcca agtccaagcg
    21361 tttcatcacg ccaccggcct ttagacaatc ctcgaaaaag tcgtaccagc tacgcttttg
    21421 agcgagtaaa aaagtttcaa attgtcggca acctcgcccc tttaattcta aaagcacacc
    21481 tttatcttct tcatgagaca acatcaccac aatatcaccc atgacatact gttcttgata
    21541 ggagtaaaag gcataatctt catggagcat atactcaaat ttcaaatgga gaatttcttg
    21601 aataattttt cgtgcatccg ttgtgggaaa gcgaatcctt acatagtcaa acagtaacgt
    21661 caaaggcaaa tcgggattaa agctttccag ttggtcaaaa attttcctca tggtttttat
    21721 agatgcggtt acgccaccat tttctatctg atttaagtac ggccgactaa gtccacaagc
    21781 cgtagccaat ttattttgtg aaacgccgta ttcgttgcgt cggtctttta atagccgata
    21841 atctaaattc cgttgtgcca agttctcacc tccaaattca aggtgttaac tttttcaaat
    21901 gagttaacac ctatacaaat tacttactat ctttgataca acaagcattc ttaatggttg
    21961 cttacttatt ttttgtgttt ttgtaccccc ctgttagata cgggggtgag acatcatggt
    22021 cggctaacgc cgtccatgaa caggcacagc accacggagg atttctgctt cgcgaatcct
    22081 ccgcggtcag cgcctaacag tcagttgtgt tggtttaggt tactcatctg taataccatt
    22141 tacttccaac tctgctttca tttctaacaa gtattgacga atatctggtt cttttgcttg
    22201 gtccgcaatc cgctcaaatt ctgcaattac ttgatttatt tcaattcgag catccgtctc
    22261 ctcattcatt aaatatggat cgccagcgac tttgacacca ttcttgcgaa tatcaaattt
    22321 taaccgtcgc aattgttctt ctaattctgg gtctgactga atctttccaa tcacccaata
    22381 aatttctcca atcaactcat cataaaccat gtacatccaa ctcttttaat cttctggcaa
    22441 tatcaaaaat gaccggaact gttacagagt ttccggcttg cttatacaac tgactatctg
    22501 aattgacttg agaatctcga tcaaaagccc aatcgggaaa gccctgaagt cgccaacact
    22561 ctctaggtgt tagcttccga atttgatact gatccgtgac gatcgcttgt tggtctcctg
    22621 ttagtaaggt atgaacactc tgttttccca gacgacctcg gcgacttgtg gaattaggaa
    22681 aagccagatt cacactgtct tctggcttca cctcttgata ttctgtttca ttttttcgaa
    22741 tcatgatttt tgtaccacct tgtttcgttg acaaggtggg ggcggttcca gtaacttcat
    22801 aaactcgatt accttgttca aactttcccg gtaatagtcc tgctacagag attccatccc
    22861 ttgctggcag tgcgattttg attccttcat cacctgttaa ggttggcgct acgccatctg
    22921 aaccatagac ttgtccaccc attcctcgat tggaaggatt gatatttacc aaatttctga
    22981 tgttttgatc agatgttgaa gacggtccaa tgataggaaa tacttgttcg gtacatgcgt
    23041 ctcgagaatg tccgataagg aatatccgct cccggctttg gggaatgtag gcctttgagt
    23101 taagcaccta ccactccacg tcatacccca atccatccag cgttcggagg atcgtctcga
    23161 acgtagcccc tccttcgtga ttgagcaatc ctcggacgtt ctcaaggaat aaaagcttag
    23221 gtcggagaag agtggtgaac cgagcgattt caaagaataa agtacctcga gtatcggaaa
    23281 atctttgccg ctttcccgca attgaaaaag cttggcacgg aaatccgccg caaaggatgt
    23341 ccactggtcc gagggattga ataaactcat ctgatacact tgtgatgtca tgcatttcca
    23401 cctccttact tgtatcatga attgctttat aactacgtct agcaaattta tcaatttcac
    23461 aaaaaccgat acaatgatgg ctcgcctgtt ccatacctaa acgaaagcca ccaataccgg
    23521 cgaataaatc taaaaatctc atacattacc tcattcattg caaagaaaaa agccaagaac
    23581 attttgctct tggctcatac attattaatt tgtcctacta ttttttattt aatccaacta
    23641 atttccgttg tttttcattg gcctgatcgg ctacatattt aatcaccgtt ttgaactctt
    23701 ttgcagtagc attttccgat aaatccgcaa tgctcttatt gtatttcttt acaattttcg
    23761 ttacttgttc tttctcagtc atgtaattga acctccaaat ctttcctact ataccctagt
    23821 ggtaaaaata attctagatt atccgtagca taatgaactt cggaaatatt attcgtataa
    23881 tcttttatta tgatatgaag caatacatct ggatgtttac tctttacttt tgcaatgttc
    23941 tctcttgatt tgaaaaaagc gttaataaat gcctttttcg gcacatgacg tccctctgca
    24001 atttcacgtt cttgtgtaaa tttccaagcg attttagggt cttgataaac atagaaaatc
    24061 gtcactcgaa aatgtttttt caacgcccgc gagatatttt tttcagcact taatattgca
    24121 aaagttgcat ccagaataaa agaatagcca tgatctaaga catatctaaa tgcctgctct
    24181 accaaccaag aagatgcttt ttgaaagaga ctagagtttt ttccattata atcaggaaac
    24241 tgggtgcgaa agtaatccgc atcaataatc acatggttat cataattctc agctaatcca
    24301 atggcaacct ctgattttcc agccccagga ctccctgcca taaaaactgc gtctcgtcca
    24361 acttcggggg atttcccttt gataatataa gaaataaact tatccttatt tgcttttgca
    24421 tactctaaat aagaatcatt actttccata ttaattatcc cctttcttcc tactatataa
    24481 aagtattata cgttacttga agtataaagt cagtattgaa gatcactcaa tcattcatct
    24541 tttctaattt actaattgaa tctaagaaat catacccttt tggtacaagt ggcgtataaa
    24601 actcactaat cacactgcca cctgtatcca cataacctcg acctttgatg tgcttcataa
    24661 agaagttttt ttcgacctcc ccaaacatca tggaatatcc gagttcactc atacgaccca
    24721 aagccacgcg aaagttgaat tgatcgcgga ttccgtctcc taaatatttc gcatccggcc
    24781 tttggcaagc caaaatcaga aagaaaccag attgacgacc caacatcacg atttgtttga
    24841 gcttattcaa aatcaccgca ctttctttcg tcgttaacat ctccatataa gccacgtatt
    24901 catcaaagat taaaaagttg ggtggaagtc caagataggc ataattctct cctgttttgt
    24961 agttagacat ttctttcatt gccttgctac gagccatcat acgttcatag aaatcttcca
    25021 cacaagcaga aatttcttcc ttttgtgaat aaacatgagg catcaccgta cctaaatcag
    25081 ctaaatctgc atttttggga tcgaggataa acaattctgc atctgacttc aatagtgctt
    25141 cgataatggt gaggaggaaa taggtcttcc ctccacccgt gccaccagcg attaacatat
    25201 ggggtaaaga atcataagcc catacttgat ttttcatcaa tcgcagagtc ccattttctg
    25261 ccactacttc gtctatccca attcgattgg cgatcatatc atacagtaaa gtatactcca
    25321 cataggagtc tttgagttcc ttttctacta actcacaata cagtccgctt tctaacttct
    25381 tttccaattt taaaagctga tcttggtatt tcccaagtga aatttgaacg cgaatagaca
    25441 gtaatccatc tttcattcga taacagattt tggggaagta actgatagtc tctctggttc
    25501 ggctactatt caaatctttg aaaaagcctt cactttgagt ttgtttcact tcataccaat
    25561 ggttctctag aatcatccga gctagctttt gtcgatgcca caagcttcgc caatgatcaa
    25621 gaaaaaagtg aatataaagc aatatcatag ctcctgaaaa agcgagactt ccaagcagac
    25681 atactaaatc ttttatagac caaacgattt caatagtaga aagtgatagc ttagaaatat
    25741 caaattgtct aaactcttga aaataaaaga cgctcatcca accgatgaac agagcgagta
    25801 gccagccaag aacaaagtga taaaccaagt gctgatctcc tgcgcgtatg cgatgtcctt
    25861 tgtacatttt gatggtttcc acctccaatc gaaaaagccc aataggattt cattaggcaa
    25921 tttcaaaaag ttatgctagt catttactgc tacgaggagg ggagttgttt cgtttcaacc
    25981 aattgattta aaaagccttc aatagcatcc ggcatctcca caccaatttc ttccaaaatg
    26041 gattctgcct gccgacataa gttttcattt acttcgacaa ctataaagaa agactcttct
    26101 tctcctaacc agtctagtac atcagagtct tcttcactgt cgctattttc tccaagtaaa
    26161 ccttgatgta taatcagaaa cattttttca tcagaggtta atgctttaac gagttgttcc
    26221 tcagtcagct cgccttttcc atattgatcg agacaatcta aaatatgttc aacattaatt
    26281 tccataatct tcacctattt ctttctttca ttttggttcg taggatttcc ttgattcggc
    26341 tgccgcttca agactaaatc atccgcctta atgaaccaat taacggtagt tccttctcga
    26401 aaaacataat tggcaacggt atccacgatt ggattgacca actctacctc tgcatcataa
    26461 gcaaactcgc gtaagggtac attagctggg atactaactt gaatcattcg cccttgtgca
    26521 gaggatttta aattataggt tcgttctttt acctcattac caattgttcc atcctcattt
    26581 tgcttccgta cttctcggcg taatgcggaa aaacgcaact tcccaaatgt taaacctgaa
    26641 tctacgacaa taccttctgt taatctcatc ttcttttcct cctatgcttt cactaaatca
    26701 tcaacataca acacgtaatc agtaaaccca cgattctcaa tctcatagcc tttggcaacc
    26761 aaatggggat tcacggcttt tagcggttgg tcttgatcaa aatccttttc accggcttcc
    26821 gcagctacta ccacctcaat atcatcggcc cgttgcttac tggaatacaa atgataactg
    26881 cgaccaatca ccgtagtatt ccgtccatat ccttctgtta taatttctcc ttcaccggca
    26941 taacttaact ttccaaaggt ttcagccata tctggcacga caaatttcaa ttccatcttc
    27001 ttttcctctt ttcattgtta gttttggata caaaaatagc gcgactactt ttttaggagg
    27061 cggtcgcgca cgttggttct taggatttac ttgtatcatc tcatcacctt agttccggcg
    27121 attccagaaa taatagcccg ccgtcgcaaa aatcaaagta aaaccaatga acagtaaaac
    27181 attggaattt ttctccccgg tttgagggaa ggtcttcact gtgggactag attcttgaga
    27241 gccacttgga acagttggtg tttccggttg tttcggcgta cttagtatgg ttggaacttc
    27301 ttttggtgtt aaggtttgag atttttcttt caaatcttca ttgtgttttc cattgatatt
    27361 cccatcttta tcgtaattga tttccgcaaa agtaaacttg gttccttctg gatattttcc
    27421 ggtatctact tttttcgcaa gcacagtttt ggtgaattct ttatcattta cttcataatc
    27481 aatcttgcca gatttccaaa tttctttgtt tgtaccatcc ggtaataaag catacagaat
    27541 tgtttcgaaa gcttcttttg agccatccag tacatcatga gtaatcgaca catcatcaaa
    27601 catatccacc acatcaccat gagtaaaggt ctgagaaccg ttttctaggt gggcctttgt
    27661 ttggatagaa acatggtgtt ccactgtaca actgacagtt tgggcttggt tattcaagct
    27721 aacatccttc gctactggct tatcgcctgc ttcaaaagct tccttatttt catacacata
    27781 gttgaataag acaatagttt tatttaaaac ttgttcggcg gttaatttat gctgaatttt
    27841 ccaagttcct gttttctctt tgttcgccaa cgttgcgctt gtttctgcaa tcaccactgg
    27901 tttggctttt tcatcttttt cttgggcagc ttttgtcgca tccacatcaa tggcttgcgc
    27961 taccacatac cagtcttctt tgatttcatg tagattgtaa ctcaatttat caactagctc
    28021 ggtagaatcc agagaagtta attctttgtt tccgtctttc caagtcgcaa gagaagttaa
    28081 actatcttct tcctcaggca aatcatagag cattaaacgg ttcaaactaa cagaaaatgc
    28141 tttgttcgtc agcttctcgt aaggaacggt caccgtttta attggttgtt tttggtcttg
    28201 ttcggtaatg gtaaagacat actcactctt cacaaagtct tctttgtttt ccttaaaagt
    28261 agaacggatt tctaatggcg taatcttttg aaaaccttct ggggcttcta cttcttcaag
    28321 taaataatcc ccataaggaa gattttcaaa cttgccataa ccatcaaacc ctaattgctc
    28381 gttataagct gtggtcgctt catcttcggc acctgtgatt tcattggtcc cttccaatgg
    28441 cgacacttta aaggtcagat cattgaagcc agtttcggta gtgcccgcag ctgatccagc
    28501 aaatttaaag aaatcaaagc caaagcgaat cacttgttct tttgccgtaa catttcgggt
    28561 aatcacggca tttttttcgc tatcatccac ctttttgatg gatacaggat actttgtttc
    28621 atcaaggcta tatccttcgg gcgcttttgt ttcttggcaa taatactcgt tgatagctaa
    28681 atgtttaacg gcaacttggt tcttttcgtc taaagtcaaa gtgaccgttt catcagaacc
    28741 tttcgttccc ttcgctaact ctggtttaaa agcctcactc catttaacag cttttccatc
    28801 cttagcagta aacaaggtgt attcagcacc ctcaaagact gccttacctt gtgctttatc
    28861 cccagtatct ttgtcttctt tcgtcaaagt ggtttcgcca gtgacttctt gattttgccc
    28921 ttttacgtta ctggtaacag gggctacggt ttgattggca tacttcaatt cgacttttac
    28981 aggtttgaac gtattcacga acccatgact agctttagtt tcggtcacat aataggttcc
    29041 caattccaac gcattagcaa tctcttttgg tgtttccgca tgaccgtttt catccgtggt
    29101 catttcttga acgatttcac cggttggact gtctttgcga atggcaaacg tattaccagc
    29161 taaggaataa ttgtcattcc aaagatcact ccctgtttca actccgcttt tatccagaat
    29221 gatttgccct ttttcccgtg cgttttttga agtcacgtaa atggtttcgc ctgctttaat
    29281 ggtggtagtc atgggggtgg tatcaatcgt ataaggcgcc ggtactgatt tttcggtaat
    29341 ggttactttt gtaccatgag gaatctcatc caatgtagca atgccttctt tgtcagtagt
    29401 cacgtctttt gcaggtaaag tttttccaaa gtctaaatgg aaaaccgttc ctggtacaac
    29461 atcacccgat tctttatcga cttttttgat ctttaaagaa ccctccgttt ccacatcaat
    29521 tttgattgtg taggtattag gtttatcaat cgccccggcc attaaagtct gttggccagc
    29581 ctttttatag gcgacaggtg ttccggtacc agcagatttc ttaagcgtca gcacaccact
    29641 ttcttttgaa ttggcatttg gggtgattat caactgatta ccattcacac gataatcaat
    29701 gtttgcggca ttttccacaa cctcatcgaa ctctgacaaa ttcagattat tcgtatccgt
    29761 cacagtagtc gattgcccta atactgtttt agccgtacta ttatggaagg ttggtttctt
    29821 ctgataatcg tcaatggctt gatttatttt tgcctcaatg gctgcgatat ttacggcact
    29881 accatctgat cgttttattg agtgaagggt atacccatta acttcttgcc agatcatctt
    29941 ctgtgccaca atatgagtat ctgcatctgt acctactttt ttccataaaa cggaaactaa
    30001 tttggcttta tcggacatat ctggtaacgg gtttttctca tagccaggag tgaactcatt
    30061 gtaaatcggg actcctggtt caatacagaa aatatcttgt ttaaagccgt tgtacactgc
    30121 ataatgcgga acagtgactt ctgacattgg acgaccatca ctaaaagttc cttcaacagc
    30181 atattgatgt gctaaatcta gttctacggt taccgtttgt ggatgggtaa tttcatcagc
    30241 aaaagtaatc gtaggagcaa ttgctccaac aattgcttga acagccaaac tcaaaatagt
    30301 taatacacat aatttctttt tttgtttttt atacatgaaa tgttctcctt tcaaattaag
    30361 cacaaaaaaa taagatgctc gcttgaacat ctttgtttat aaagtctttt taaaattttt
    30421 attgactgaa tagaatggat ttgagaatga atgagcctaa aaatttaatc taaaatacga
    30481 aatatactgc ctttaaatta gaacacattt tagaacacaa acatttcaaa tttaatcaaa
    30541 tataataaaa tatatttacg ggaaaacctt tataaatcaa ggtttttcaa acttattcaa
    30601 tgatacgaag aaaaaaccag gtcttaagaa agcccgtaaa gcttcacagt tctcaaaacg
    30661 ttaattgcga ttatcgttcg agttcacgag ttacgagaat cgtactgggc gaagcaatgc
    30721 tgagcgcagt taccttaatc ctaacttttc tggcactttc cacaatttgg aaagtgcctt
    30781 ttttgtgttt ttagctatgt taataggtag gattcttggt ctataatatc attcgatcta
    30841 taaacaaacg ggaaaaagat aaagtatcat caaacaatat tatttatccg cttctgaggt
    30901 tgtgacagaa gtggtcagct tcaagaaata agaaggaatt tacaaaaatt gcttctcatg
    30961 tttgataaat attgtgactt gtgaccgagg agttggcagg agaacaccgt ttattcggaa
    31021 gaagggattg tgaaaagtct tttgtcataa cctcttattt ggtagctaat tgtaaatccc
    31081 aaacggcatg tattattttt cataagtccg tttttaagga ttaatgtttt cttttgcttt
    31141 ttatatggtc tggcttcagc gagaagttcc aacgcatata caaggacgac ttatgtcaac
    31201 gataacaacg attaccatgg tggccagtcc acttggatta gcactgtttg gtgcgctctt
    31261 tgattggaag acaacgcaac cacgtctgcg agacagtcta atttttctgg gagggagtct
    31321 tgctatagtt atccttataa ccggtctggt aaaattactc aagcttgatc tgaaagaagc
    31381 aaaaattttc agtgaagagg aatacagaga aacgactttg gtcgaaaaga aagaatcagg
    31441 aaactgatac aagcgtataa caaactgcct gataatagga aagacacgta ttgtccgatt
    31501 gttttttttg acattcaatt ggaaaattta cactttcttt atacatttct ggctgctttc
    31561 tttatacccg tcaactatac ttcactcatc aataagaaag aaggataagt atggattttg
    31621 gaaatgaaac ggtcttgaaa gcaactggta taaccaaaaa atacggtgct gccaaagcat
    31681 tagataaagt atcaatcgaa atcaaacgtg gaatgatcta tggattgatt ggggaaaatg
    31741 gagcgggtaa gtctaccttt atgagaacta ttatgggttt gatctcgatt gatgaaggtt
    31801 cgatcgaatt atttggaacg acggatttgc aggcagcaag acgacgtatg ggtcaatcga
    31861 ttgaaacccc tgctctttat ccagaattaa ctgcaagaga taacctacgt atccaagcag
    31921 cgaacggcgg tgtgtcggat agagaaatcg aagacctgct gaaaatgatg cgattggaaa
    31981 atacagggaa aaagaaagca aagaatttct ctttaggtat gcgccagcgt ttagctattg
    32041 caaatgcact gatcacgaat ccagaatttt tgattttgga tgaaccgacg aatgggatgg
    32101 atccagcagg gatggcagaa atgcgagaaa tcatccaacg tttggtaaaa gaacggggca
    32161 tcaccgtctt gctttctagc cacttgctag atgaattgtc acagatcgcc actcactatg
    32221 gtattttgca tgaaggacac ttgatcaaag aattatcgaa agaagaattg gcacaagaat
    32281 ctcgtcaatt tataaaaatt gacacttcgg cgacggaaca agcagtaacg gttctcgact
    32341 ctcttggtta tagggattat tttgtacaat ctagccgtgt tatccagctt tttgaaggaa
    32401 ttgaccaagt agcagccatc aatcaagcat tggtagaagc aaaagttcct gtggatggta
    32461 ttcacctagt tgggcaaaaa ctggaagatt atttcttaca attaactgga ggcaatccac
    32521 atgtttaatc tattaactgc tgaaaaaata aaagtatgga agagccgtaa aatgtgggtc
    32581 tcactaggac tgatggtcgt acttccgctt ttttattctt ggaacgaatg gtatatgcat
    32641 acaaaatacg gcaatgaatt aaaccaagca acggatacag tcatcaacgg tgcaacaggg
    32701 attttaatgg tagaaaaaat ggctgcatgg attcttctgg ctttcgcagc atttgcgtgc
    32761 ttttatattg gggaagaatt tcaaaacggt acgattcgca atacgttatc tttaggacgg
    32821 aatcgaatga cttattatgt gtcgaaactt ctcgttacgc ttttgatcac aacacttggc
    32881 gtggttttga tcacgggact agccatgctt gcttacacac ttgctttcgg atttggtgaa
    32941 gttgagggaa tcaaaaacta tggaaattat gttctaaaag tatttcctgt attgcttctg
    33001 ctgacattag ggacattatc tgttccagtg gctttgacat tcatcactag aagtaccagt
    33061 gtcagtttgc ttctttcttt tctttatatc atgggaacgg ccttcattcc cggtgttttc
    33121 gcaaaaatca aaggcttgga atttctaacg gagtggttta cggaaacgtg gctcatgtat
    33181 acggactttg cgcaacaagc aacttattcg caagcaccga aaatgattct ggtcagtcta
    33241 gtaacaatcg tggtatcatc agctctagga atgtttattt tccaaaaatc tgacattaag
    33301 taggtggtcc tgctggaaac tattttgatt atcgaagacg atgaagctgt tcattcctta
    33361 ctggaggagg ttcttgaaca gagatacaaa cttcttgatg cttattcagg tacggaagga
    33421 aaattattgt taagcacata tcctgtcgat ttgatccttc tagatctcat gcttccaggg
    33481 ctttcaggtg aagcattgtt agcagaaatc cgacagacat cgaatgttcc gatcatcgtt
    33541 ctttcagcaa aaagcgatca aagagataaa gtttccttgt tggcagcagg agcggatgac
    33601 tatgtgacga aaccatttga tatcgaagaa cttttgttac gaatcggcat ccaacttcgt
    33661 catcagactt ctgtccaagt aaaagatctg tcgcaacgca tctattacaa ggaaatctta
    33721 ctggacaaag agtcgaggga tgtaaatgtg aatggtgtgg ctgtccattt gacaggaaga
    33781 gaattcgatc tgctgaagct ttttttagaa catccgaaaa aagtattttc gcgagcaaat
    33841 ctttatgaaa cagtttggca agaaccatat tttgatagtg agaaaacagt gaatatgcat
    33901 atttccaatc ttcgagggaa gctagcaaag gcacatgctg tgtatattca tacggtgtgg
    33961 ggagtggggt ttagatttga ttaaatggct gttgcttctc gttgttatct ttatgggaag
    34021 ttttattttc ttcctgcaaa gggaaatcaa gagattaact aagaaaatcg ccactctttc
    34081 tgaacgacaa gaatatggtg gtcgtctttc agtcgaattt cgagaaaaga atctaatgga
    34141 cctagtagat gcactgaata catggttgga tgaaaatgaa caaaaaggac aagcatttca
    34201 agaaatggaa gaaaacatca gactatcgat cgtcggcctt tctcatgatc tcagaactcc
    34261 tttgactgct attaacggtt atgtacaatt actggaacag gtagaggata cggagaaacg
    34321 ggagaagtat ttaacgatca tcaaacaatc tgttgcaaga ttactcagta tgacggatca
    34381 gttttatgat cttgctcgaa tagagacgaa gcaaaaagaa atggatctcc atacgctttc
    34441 tttttctaaa gaggtggaag aagtattttt ctctttttat gaacaatttt ctgagaaaaa
    34501 tatcgaggta gcgttcgctg aacactcgat aaatacaact gtattagcag atccgctcat
    34561 gttgctgcga gtgctgcaaa atatcataca gaatttattg cgttatgcag atggacaagc
    34621 aaaggtgaca ttttcaaaag aggatccatt cattcgatta acagtggcca atcctatcaa
    34681 accaggaacg caaacctctg ttgaaaaagt cttccagcgt ttttataccg aaaataccag
    34741 ccgcacaaat acggaatcta gcggaatcgg gctttacctg tcaaaaaaat tggtggaagg
    34801 aatgggagga gagatgaccg ctagattaga cgggggcatc ttctccatct ccgtcaagtt
    34861 gcggagggtt taattataca agattagtga gaactagtag aaaaatgtat tatc
//
LOCUS       DAPBBV010000029        34184 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.029, whole genome shotgun sequence.
ACCESSION   DAPBBV010000029 DAPBBV010000000
VERSION     DAPBBV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.029"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            337..2502
                     /gene="acm"
                     /locus_tag="RD486_001764"
     CDS             337..2502
                     /gene="acm"
                     /locus_tag="RD486_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HDT7663494.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2774..3259)
                     /locus_tag="RD486_001765"
     CDS             complement(2774..3259)
                     /locus_tag="RD486_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDT7663495.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3349..3694
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3739..4380
                     /locus_tag="RD486_001766"
     CDS             3739..4380
                     /locus_tag="RD486_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7663496.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4399..5034
                     /locus_tag="RD486_001767"
     CDS             4399..5034
                     /locus_tag="RD486_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7663497.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            5052..5867
                     /locus_tag="RD486_001768"
     CDS             5052..5867
                     /locus_tag="RD486_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7663498.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6186..7622
                     /locus_tag="RD486_001769"
     CDS             6186..7622
                     /locus_tag="RD486_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7663499.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7811..10258
                     /locus_tag="RD486_001770"
     CDS             7811..10258
                     /locus_tag="RD486_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7663500.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10488..11555
                     /gene="rlmN"
                     /locus_tag="RD486_001771"
     CDS             10488..11555
                     /gene="rlmN"
                     /locus_tag="RD486_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDT7663501.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11748..12851)
                     /locus_tag="RD486_001772"
     CDS             complement(11748..12851)
                     /locus_tag="RD486_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7663502.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13404..13952
                     /gene="aac(6')"
                     /locus_tag="RD486_001773"
     CDS             13404..13952
                     /gene="aac(6')"
                     /locus_tag="RD486_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDT7663503.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14498..16159
                     /locus_tag="RD486_001774"
     CDS             14498..16159
                     /locus_tag="RD486_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7663504.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(16229..16576)
                     /locus_tag="RD486_001775"
     CDS             complement(16229..16576)
                     /locus_tag="RD486_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HDT7663505.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16660..17601
                     /locus_tag="RD486_001776"
     CDS             16660..17601
                     /locus_tag="RD486_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663506.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17602..18645
                     /locus_tag="RD486_001777"
     CDS             17602..18645
                     /locus_tag="RD486_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663507.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18651..19721
                     /locus_tag="RD486_001778"
     CDS             18651..19721
                     /locus_tag="RD486_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663508.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19711..20664
                     /locus_tag="RD486_001779"
     CDS             19711..20664
                     /locus_tag="RD486_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7663509.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20676..21686
                     /locus_tag="RD486_001780"
     CDS             20676..21686
                     /locus_tag="RD486_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7663510.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21971..22792)
                     /locus_tag="RD486_001781"
     CDS             complement(21971..22792)
                     /locus_tag="RD486_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7663511.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22889..23167)
                     /locus_tag="RD486_001782"
     CDS             complement(22889..23167)
                     /locus_tag="RD486_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663512.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23435..25444
                     /gene="metG"
                     /locus_tag="RD486_001783"
     CDS             23435..25444
                     /gene="metG"
                     /locus_tag="RD486_001783"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDT7663513.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25923..26510)
                     /locus_tag="RD486_001784"
     CDS             complement(25923..26510)
                     /locus_tag="RD486_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663514.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26685..28007
                     /locus_tag="RD486_001785"
     CDS             26685..28007
                     /locus_tag="RD486_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7663515.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            28162..28938
                     /locus_tag="RD486_001786"
     CDS             28162..28938
                     /locus_tag="RD486_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDT7663516.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28931..29500
                     /gene="rnmV"
                     /locus_tag="RD486_001787"
     CDS             28931..29500
                     /gene="rnmV"
                     /locus_tag="RD486_001787"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDT7663517.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29493..30377
                     /gene="rsmA"
                     /locus_tag="RD486_001788"
     CDS             29493..30377
                     /gene="rsmA"
                     /locus_tag="RD486_001788"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDT7663518.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30828..31457
                     /locus_tag="RD486_001789"
     CDS             30828..31457
                     /locus_tag="RD486_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663519.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(31581..32690)
                     /gene="ugpC"
                     /locus_tag="RD486_001790"
     CDS             complement(31581..32690)
                     /gene="ugpC"
                     /locus_tag="RD486_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDT7663520.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32899..33321
                     /gene="mgsA"
                     /locus_tag="RD486_001791"
     CDS             32899..33321
                     /gene="mgsA"
                     /locus_tag="RD486_001791"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDT7663521.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            33644..34180
                     /locus_tag="RD486_001792"
     CDS             33644..34180
                     /locus_tag="RD486_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDT7663522.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
BASE COUNT        11391 a         5916 c         7068 g         9809 t
ORIGIN      
        1 tagtataaac taataatgtt aattaaaagt gtattttatg aaactatcgt tatttattaa
       61 tgttgcattt ttgtaagtta aaaattggaa atatagattg aaaaaatgaa agcaataagt
      121 aaaataaaat gaatatatgc gaaaaaataa tttacattag gaaaaacctt gtaaaaacag
      181 ttttttggca tatttatttt ttataaatat ttgtaaaata actatcaatt ttttagttaa
      241 aagattggaa atgagtgggg gaggaattga agaaaggatt tttgagagat gatatagtag
      301 gttttatttt tagttaaaat aggggagata gaaaaaatga aaaagtgtag aaatattatt
      361 ttatcaatgt tatttattat tactaatata acatcactga ttcctgttca tgtctatgcg
      421 gatgcaggca gagatatcag cagtaatgtc acttcgttga ccgtggaccc aacgaatatt
      481 acagatggag gaaacataaa agtaaaattc tcgtttgacg aaaaaaaaca aaatatccaa
      541 ccaggtgatt atctttggat caattggcca agtgaaggaa atattcgcgg tgaaggattc
      601 caaaaagaaa tcccattaat gattgaaaat aaaaatgttg gaactttaac ggtcagaaaa
      661 gattctgcgc aggttgtgtt taatgaaaat attaaaaacc tagactcagt agaaggttgg
      721 gggcaatttg agatacaggc cagaaacgta accgataccg gtgaagaaaa tacgggacca
      781 ttcaccgtga cgagcggtga taaaacagct actgtaaatg tgacaaagcc agcttctggt
      841 tcttcttcta gcgtttttta ttataaaaca ggagacatgc tacctgaaga tactaagcac
      901 attcgatggt ttttgaatat taacaataac ggcacttatg ttgaacaacc agttaaaatc
      961 agtgatgaaa tccaaagtgg acaaagatta gatccaagta cgtttgaaat taatcaaata
     1021 cacttaggtg aacagaaggt ttatagagga gaagagggaa tccaacaatt tttacaagat
     1081 ttccccagcg ctacatttaa tttttcagta actgataatt acattgaaat aactatacca
     1141 aaaaactttg tcaatcttag gaaaataatg gtgagttata agacgatcat agaaaaccca
     1201 gaacaaataa attttgagaa tcattcggaa gcttggttta aagaatttaa taaacctgct
     1261 gttgatggag aaagtttcaa tcatacagtt aaaaatattt cagcttctgg tggagtcaac
     1321 ggtacagtta gaggcgaatt gaagattttc aaatatatca atgacacaga gattggtatc
     1381 ccaaatgtga ctttcgaatt aagacgagca gatgaacagc ctattcaagg acagtctagt
     1441 atcctgttga cttcgaatga acagggagaa gctagtatca aaggcctgca agtaggagac
     1501 tatgttgtaa aagaaaaaga agcacccaat tggattgatt ttgatccact aagttcaaat
     1561 gaactcaaat tctccataaa cgaaaatgat acagagggag tcagtttacc tatttataac
     1621 aagaaaaagg ttacgaacat cacagcaact aaaatttgga acggtggaac cactccaaga
     1681 ccgagtattt attttaaatt attcagagca agtacaaaca attgggaacc agttcctgat
     1741 gcagaaacaa aacgattaga caatggaata acttcagtga cttgggaaga tatccaacag
     1801 tatgatgata gtggaaacga atatacgttt aaagtgcaag aagtagatca aaacggaaat
     1861 gattatgtcc cttcaggtta tcaaaaaatt gaaaacgggc tagtcgttac aaatgagaat
     1921 aaagaagtca tttcagtctc aggacaaaaa acatgggaag acaatgagaa ccaagacggc
     1981 aaacgaccga cgacgatcac agtaaatcta ttagccgacg gtcaaccgat ccaacacaaa
     2041 gaagtaagtg aaaaagatga ttggcgctat cgtttcacaa atctgccaaa atacagagac
     2101 gggcaagaaa tcatctatac tgtaacggaa gacaacgtgc ccgaatacag tacgacgatt
     2161 gacgggtata acatcaaaaa cagttataca ccggaaaaaa caaatatatc tataccaggt
     2221 agccatataa caccgtggaa aaattttcca gagaagacag agagagagaa aattagaaat
     2281 ctattctctc aaaaattgca aatatttgct catacaggag aatccagcga acaaagaagc
     2341 aattatatta gtaagagagc tgtacctaaa cagataacaa ataaatcaaa aagcattctt
     2401 cctaaaacaa gtagtaaaaa atctagtttt gctgtaatca ttggtttatt gatagtaact
     2461 atctgtgctg ggatattctt acaaaaatat aaaaaagttt agttagaata taatattttt
     2521 tgttaaatat gactgaaatc aaaagaataa aattccgatt tataatcgaa aaaagaagca
     2581 tttttatata tgcttctttt ttcgtagaat caataaatat ggatttggct aactatggaa
     2641 gaatactcgt attagttttc agcgttcata ctagttgtta cattgtttga ttggccaaaa
     2701 gaatttctga tatattttgt gctaaataaa gaaaaagacg cttgaattgg gaaataagaa
     2761 aactactcta tcattacaaa ttttcataaa ctggcagatg ttctaagtaa acaagtatct
     2821 tttcaaagtc ggaaaaatcc ataatcaacg tagtggtatt gatatttgga tgaaagccta
     2881 cggtatcttg acgatcaata gcagcatcga tcacgacttg gatttttttc tctttgtcgt
     2941 gcatcaatgc taatggagtc actgtacctg ctggaacgcc taggaggtca ggaagctgtt
     3001 cttcagaaac aaaagataag cgcttttctt ttaattgttc agctagttgt tttaaatcgg
     3061 cgtgcttttc atcaggcaag atgacaagat agatttgttt tccttttctt gatttcaata
     3121 atagattttt tacttgcgga ccaggtaggg aaaaagggac atttttgact gacgtaatcg
     3181 caggatgatc gactttttga aaagagatac ccagtttttt tagtagttca taagcttctt
     3241 gttcggttgc acgactcatc gcgcatcacc ctcctttttt tattagtgta tcataaaaaa
     3301 gagttgacaa atgaaaaata atcatgtaaa ttacacgtaa agttaaaaca aatgacatcg
     3361 aaaagaagag tagccgttag gtgtttttag agagtctctg gttggtggaa agaggcagca
     3421 gttaaccgtg aaacacatct tggagtcgat tttctgaagc gtatagtagg aaaatccggg
     3481 gagcccgtta cagctgcggt cgttgctaga tgaccagata aggctggctt ttccgtgagg
     3541 agtcggtaaa aaaaggtgga accacgtgat taacgtcctt tgatcttcgg atcaaaggac
     3601 tttttgtttt catctgaacg gcaacgactg tgtgaggttt tttctgcaag gaaaaaataa
     3661 acagaggtgg aaccacgtat aatacgtcct cttggcattt gccaagagga tttttttatt
     3721 ttaaaggagg aaaagaagat ggagtatttg attgaagtta tgccgcaatt attagtagga
     3781 gcactcacaa cattgaaatt atttttattt accttgattg gctcattacc attagggatt
     3841 gttttagcat taggattgtc tttgcatttt aagccgctac gctacttgct tcaaacatat
     3901 gtatgggtta tgcggggaac accgctgttg ttgcaactga tttttatttt ttatgggttg
     3961 ccgacgattg ggatcgtttt tgatcgtttc gaagcagcac tcattgcctt tatcttaaac
     4021 tatgcagctt attttgcaga gatctttcgt ggagggatac aatcgattcc tcaaggtcaa
     4081 tatgaagcag cgcaagtttt gcaattaagt ccctttcaaa cggtgacgaa aatcgtcatc
     4141 ccacaagtga caaagattgt tttaccttct gtagggaatg aagttatcaa cttggtcaaa
     4201 gattcttcct tgatctatat attaggttta ggtgacgtaa tgcgtgctgg gaaaatcgcg
     4261 atggaacgcg acgcgacttt actgcctttg ctaggcgtgg caatcatcta tcttacattg
     4321 actggtattc taacaatcgt aatgaaacaa gttgaaggaa aattaaatta ttaccgctaa
     4381 ctgataggag gaagaaatat gattgaattg aagaaagtga acaaagcatt tggtgaaaaa
     4441 aaaataatca aagatttgaa tctaatcatt ccagatggga aaacattagc tatcgtaggt
     4501 ccttccggtg gcggtaaaac cacgctttta cgtatcttgg ctggcttaga aagttctgac
     4561 agcggagaat tttatttaga cggtgtaccg ttcaacccat tcgagcttaa aatgaaagaa
     4621 caagttgtag gagtcgtatt ccaagacttc cagctatttc cacatctgaa tatttttgaa
     4681 aacattacct tagcaccaaa aatggtattg aaacagacaa aagaagaata caccaaaaaa
     4741 gcagaagaat tagcggcttc attagggatt agtgatttat tgaatatcta tccttatcag
     4801 ctttctggcg gacaaaaaca gcgggtagcg attgccagag cattggctat gaatccacgg
     4861 gtattggctt atgatgaacc aacaagtgct ttagatcctg aattacgcca gcaagtcgag
     4921 cgtttgatcc tatcattgaa agaagatggg gtaacccaaa ttattgtcac ccatgattta
     4981 gtatttgcag aaaatgtcgg tgatcaatta ctaaaagttt ccccaattca ttaagaaagg
     5041 agaagataga gatgaaaaaa accagttttc tattcgcttt gatcgcaggt cttcttcttt
     5101 ttgcaggctg ttcgaacaaa aaaacttcag cagataattg ggcgactatc aacgaagaga
     5161 aaaaaatcgt tataggttta gacgatacat ttgttcctat gggatttaga gataaagacg
     5221 ggaagctcac aggatttgat attgatttag ccaaagcagt ctttgaacaa tatgggatta
     5281 cggtagactt tcagcccatt gactggtcaa tgaaggaatt tgaactgaac aatggaacga
     5341 tcgatttgat atggaacggc tattccaaaa cgccggcaag agaaaagaaa gtgcaattta
     5401 caaaacctta tatggaaaac gatcaagtgc tgatcacacc taaagaatca ggaatcacaa
     5461 actttggaca aatgaataat aagagattag gtgcgcaaaa tgggtcatct ggttatgatg
     5521 tatttacgaa acaaccagaa gtattaaaag agatagtcaa aaaccaagat gctgttttgt
     5581 atgatagttt taatgaagca ttgatcgatc tgaaaagcag acgggtcgat ggtctgctga
     5641 tggataaagt atacgcagac tattatttga aacaaagaaa cgaactagaa gacttcaaca
     5701 taacaaaagg ttcttatgag agtgaggatt ttgcagttgg tgcacgcaag tcagatagta
     5761 cattagtgaa aaaaatcaat gaagccctag atcaactaga gaaaacaggt gaattccaaa
     5821 aaatatccga taaatggttt ggcgaagatg ttacgccgag aaattaacaa ataggggact
     5881 gtgacaaaag acgtgtcaca gtcccttttt ccgaataaac agtgttctcc tgccaactcc
     5941 ttgtgactcg gagctgaatg gcaggctcac aacctcttgg taaacggtgt tcaaaagcca
     6001 gtttttcggt attaagccaa atttatgcaa aaatgtagaa agccattttc acaaaatttt
     6061 tcttactact cgaaactaag cgactttttc acaacctcct ttacataatt ttattttgtt
     6121 gtggaagggg tttcgtgtta ttctaaaaga ggaacgattg aaggttatag gaaaggaaga
     6181 gatgaatgga acacaaagaa cttacctcat ttccaaaaga ttttctgtgg ggctctgctt
     6241 ctgcagcgta tcaagtagaa ggagcttggc aagaagatgg gaaaggagaa tcagtctggg
     6301 atcgatttgt acggatacct ggaaagacat ttaaaggaac gaacggtgat ttggcagtag
     6361 accactatca tcgttataaa gaagatattg ctttaatgaa agaacaaggt ctgaaagctt
     6421 accgcttctc tgtagcttgg acacggattt ttcctaatgg acgaggagaa gtcaatcaag
     6481 ctgggctcgc tttttatgag agattgatcg acgaattgat tgaaaacgat attgaaccta
     6541 tgttgacttt atatcattgg gatcttccac aagcattgca agatgaatat aatggttggg
     6601 aatcacgtca gatcattgaa gatttcactc attatgcaga aacattattt gaggcattcc
     6661 gcgggaaagt ccattactgg attagtttga atgaacaaaa tatcttcact tcattaggtt
     6721 atttgttagc agcacatccg ccaggtgtga cagacccgaa acgaatgtat gaagttaacc
     6781 atattgctaa tttagcaaat gcatctgtca tcaataaatt tcacgagtta gaaatgcctg
     6841 gaaaaatcgg accaagcttt gcgtatacgc caaattatcc aattgacagt aatcctgaaa
     6901 atgttctggc tgctgaaaat gcagaagacc tgatggccaa ttattggatg gatgtctata
     6961 tgtggggaaa atatccgatt gctgccatga ggttcttaga agaaaaagga tgggcaccaa
     7021 cgattgaagc tggcgatgca gaattgctag aatctgctaa accagatttt cttgggatca
     7081 attactatca aacggcgacg aatgcattca atccattaaa cggagttggt gctggaaaaa
     7141 tgaatacgac aggaaaaaaa ggttcatcag aagaaactgg agttcctgga atgtataaaa
     7201 aagttgagaa tccatttgtc gaacgaacaa attgggactg ggagattgac ccagaaggat
     7261 taaggatcgg actgcgtcgt atcacaagcc gttaccgcat gccggtactg attacggaaa
     7321 atggcttagg agagtatgac aagttgacag aagataaaca aatccatgac gactatcgaa
     7381 tcaattactt acaaagccac gtcaaagcca tcaaagaagc aatttcggat ggagcagaag
     7441 tcctaggcta ttgcacctgg tcttatacag atttgcttag ctggctgaac ggttatcaaa
     7501 agcgatatgg atttgtatat gttgatcaag acgaaacaca agaaggatct ttggaacgat
     7561 ataagaaaga cagttattac tggtaccaaa aactgattga agaaaatgga gagaaccttt
     7621 agttcacata cttaaaacaa gaaggtacgg ctggatatgg ccgtgccttt tcttgataaa
     7681 atcatttaga aattaagaaa aactgtaaaa taagctgaaa aatgaaagaa agcgtcagtt
     7741 ctttcaaaca aaactttagt tcccttactt ttttttgtat aatgaaactt gatgaaatga
     7801 gggataataa atggcacaaa agaaacggcc tactaaaaaa aggaaaaaga cgaaaaaaac
     7861 gaaaaagcaa aaacagcagc aggaacaaat gctgacgatt ggtgttgggt ttgccttgat
     7921 tttatttgct gtcttcggct ttttaaaatt aggtttttta ggaatattga ttgcaaacgg
     7981 ctttcggatc attgcaggaa atacttacca aatcctctgt cttttattag ccgtattagg
     8041 attttggatt gtcattaaga atacagagtt ttcaattggt aaaaaccgac gctggtttgg
     8101 cggcatactc ttttatttcg gtatcttatt attgttacat gcccatttat ttggcaaact
     8161 ccatactggg gaaccaaata tcatggggac gacatgggat ttgttagcca gtgatataaa
     8221 acaaagtcaa gtagacaata acgttggtgg tgggatgatt ggagcaatcc tttatcattt
     8281 tacttacttc ttgattgcac agcctggaag ttatttagca gcagtgctat tactggcagg
     8341 aggagcattc ctgttcagta atctggaagg ctatcagctg ttaaatggta tccaatcaat
     8401 tggagaacga gtacaggaat tattggaagg tgatcctgcc aagcaagctc gaaagcaagc
     8461 ggcaaaggaa gagagaatga aacagcgcgc agaagcgaaa gaagcaaggc gcttagctgc
     8521 aaaagaagct gcagaaaaag aagctgcaga atatgagaag aaaaaagcgg tgagccagca
     8581 aagggaaaat actgctgatg aatggcagga accagaaaat acagagccgg agcagctaag
     8641 ttttgttcca atcgacagtt ttcaagaaaa tatccatcct gcgaatctag agaaaccagt
     8701 accagataca ccaaaacaga ccaatacagc agaaggtttt tcagatgagt tgccagagga
     8761 tgacggtacc tcattagaat ttgagattga agcagaacag gaaaatcaag actatgaatt
     8821 accgacagtt gatttgcttg attctatacc aactgtggat caaagtgatg agtataaaaa
     8881 aattgaaaaa aatatcggcg tattagaaca aactttccaa agtttcggtg tcgatgccaa
     8941 ggtcgtcaaa gccagcttag gaccatccgt cacaaaattc gaagtccagc cggctgtagg
     9001 ggtaaaagta agtaaaattg tgaacttaac agatgatatc gcgcttgctt tagcggcgaa
     9061 agatgtccgg atggaagcac cgattccagg taaatcactg attggtattg aagtaccaaa
     9121 tggaaagatc agtatggttt cctttagaga aatcatcgaa gcacaaccaa accacccaga
     9181 taaattacta gaagtacctt taggacgtga tgtttctgga cgggtacaaa cggctgatct
     9241 ttcgaagatg cctcacttac tcgtggctgg ttcgactggt agtgggaagt cagtagcaat
     9301 taatgggatt atcacaagta tattaatgcg tgctaagccc catgaagtaa aactgatgat
     9361 gatcgatccg aaaatggttg aattgaatat gtacaacggc atacctcatc tgttgacgcc
     9421 ggtcgtgacg aaccctagaa aagcagcgca agccttacaa aaagtagtac aagaaatgga
     9481 agaacgatat gaaaaattcg cggcaaccgg agtaagaaat atttctggtt acaatgaatt
     9541 tgttcaacag aaaaacttgg aaaacggaac gaaacatcca accttaccat tcatcgtagt
     9601 gatcgtagat gaattagctg atttgatgat ggtagccagc aatgaagttg aagatgcgat
     9661 tattcgttta gcgcaaatgg ctcgggcagc ggggattcat atgatcctag ctactcaacg
     9721 tccaagtgtg gatgttatca caggaatcat caaagcaaat gtaccttcca gaatggcatt
     9781 tgcggtatca agcggtacag attctcggac gatcattgat tctaatgggg cagaaaagct
     9841 cttagggcga ggagatatgc tattcttgcc aatgggtgag aataaaccga tccgtgtgca
     9901 aggagcattc atttctgacc acgaagtaga acgggtcgtt caatttgtta cagatcagca
     9961 agaagctcat tatgaagaga aaatgatgcc gacagatgaa gttgaaacga caggtgctcc
    10021 agaacagcca caagatgagc tgtttgaaga agcaaaagca cttgtcgttg aaatgcaaac
    10081 ggcaagtatt tcccttctcc aaagaagatt tcggatcggt tacaaccgag cagcacgttt
    10141 agtagatgaa ctggaagctc atggagttgt tggcccgtca gaaggaagca agcctcggaa
    10201 agtattcatt gagcaggaag aaacatcaga aacgttgccg gacgataatg acatgtaaaa
    10261 cttgtgtgat gaagggttga aaaacgaata accaataaaa agacaaggca tgatgatacc
    10321 aaaagaaaaa atggtttttt tccatctttt ctaatacggt atgatgtctt gtctttttag
    10381 tttttgtgag attaaagttc tattcgattt atttgtgaag tattgcatta aggaaatgaa
    10441 tcatgtatag tatgtagcga aactttgaga aaaagaggga aaatactttg gaaaaacagt
    10501 ccatttatgg cttgacgaat gaagaattaa tcaattggtt tatagaaaac ggcgagaaaa
    10561 aattccgagc tgcccaagtt tgggaatggt tgtatcaaaa acgtgtaagt aatttcacag
    10621 aaatgacgaa tctatcgaaa caattgatcg aaaaattatc ggagcatttt atcatcaatc
    10681 ctctaaaaca gatggtcgtc caagaagctt cggatggtac agtaaaatat ttgtttgaac
    10741 tccctgataa aaacatgatt gagactgtac tgatgagaca agaatatggc ttgtcagttt
    10801 gtgtgacgac acaagtagga tgtaatatcg gctgtacgtt ttgtgcaagc gggctgctca
    10861 aaaagaaccg tgatctgact gctggagaaa ttgttgcaca gatcatgatg gtccaacatt
    10921 attttgatga gcgcaatctt ggcgaacgcg tttcacatgt cgttgtaatg gggatcggtg
    10981 agccatttga taattacgac aatgtaatgg actttttgca tatcatcaat gatgccaaag
    11041 gattggcaat tggtgctcgg cacattacag tttccactag tggattagca cacaaaatca
    11101 aggaattcgc taataacggc ttgcaagtca atctggctat ttccttgcac gcgccgaata
    11161 atgaggtgcg aacatcgatc atgcggatca accgaagttt cccaattgag aaattgatgg
    11221 aagctgtgga tgagtattta gagaaaacaa accgtcgaat cacgtttgaa tatatcatgt
    11281 tgaatcaagt aaatgataga ccagagcatg cgcaacaatt agcagatcta ttaaaagata
    11341 agaaaaaatt agcatatgtc aacttgattc catataatcc agtcagtgaa catgatcaat
    11401 attctcgcag tccaaaagct gatgtattga gattttatga tgtattgaag aaaaacggcg
    11461 taaactgtgt gatacgtaaa gaacatggta cagatattga tgcagcttgc ggacaattgc
    11521 gaagcaagca aatgaaaaaa acagttgcca aataatcgta tcctactcgt tttttcaatt
    11581 accataaaag gagcagtttt cttaattaag gaactgttca acttaaataa gagaaaagat
    11641 tctatagcga aagctataaa gctttttttg acaagaaaaa ccctcatcaa gcaaagaaat
    11701 gtcctcaatt tgatgacagc ctgcttgatg ggggttttag caattattta actgattttc
    11761 ttatatcctt gctggctttc ttgtgtagca tgataagttt ctacgtcaag aatggcctgt
    11821 ttaaattttt ctcgggtgat ttcataaggc acatgtttaa tatcatttgt tgccatggct
    11881 ttatctaaga ttgcttctaa atcggtcgtg acattgagat tcatgtcggt taacgatact
    11941 ggaagttggt tctttttcat aaacacatag attttatcaa acaaatcgaa ctgctgatcc
    12001 atcatcaata aggtcagtac accataactg acagatgctc cgtgaaggta tccctccatt
    12061 ttttctagaa cagtcgtacc gtaatagaat gagtgtgcca tagcagaatt atagttattg
    12121 ttaactaaaa cagaaaccaa tccggtagta acaatgatat ccgaaacgac ttgttcaatt
    12181 gcatatgagg gacgatcgtc ggcactatct ttcaatgctt gcgtaccata agtcaagaga
    12241 cgatcaatgc acatttttcc gatttggatt cctaatctat ccgtgtagcc tagatcatcg
    12301 ccacgagcag aaaaagtaga ttcgacttct ttggataaag catcgccaat acctgcccat
    12361 aagtatttat caggtgcttc ggcaataatt gctgtatcaa tgaaggtgtg tacaggtggt
    12421 tttgaaggaa agaagagtcc gtccattacg ccttcttcgt tatagatgac acataccgca
    12481 gtgacgggcg aacagttcga accaatagtg ggaaaggtga agactggttt agctagtttt
    12541 tcaccaatga cttttacagt atcgcaagca cggccaccac cgactgcaaa caggacgtct
    12601 gctttttgga cactttcatg ctggatcaac tgttcaatat ttccataagt tgaattaccc
    12661 ccgtaccaga gactggcgac aacctctatt tcctgtgtca aagctacttt tattttgttt
    12721 tctgcctttg aaagtgcagt cttccctcca atcagcacta cttttgtccc atattctttg
    12781 acgattccat ttgctttttc atacgcatct gttccaatgg tataatttgg taagaaaaca
    12841 ctttgactca tattcatttc cttctttctt cgttgaaacg ggttaaaatt ttaaagagtg
    12901 atcgatctga ctgcggctgt agatggagta gaggtgaacc taagacagga taagtgatga
    12961 ataaggtggc atgaacacct tgaaatcatc aataagtatc ctaaaaacga acaagtacaa
    13021 aaacattgaa aacgacaata atgaattttt gttcctctta gtatttctac cgattccctt
    13081 tgcttttttg taattatcta aaaattctaa aaattaagat tattatatga aaacaggttt
    13141 tatttgtcaa ttcataattg gtttttttta aagcaaaaga taatctatat catgatgaac
    13201 aaacagagtt ttttcctcca attgatggct ttcctgatct ttcctatttt gaataaagtg
    13261 tttctgtata atttttttat tttataagta agataaataa tgaaagaata gagatactga
    13321 ttggtagcta aagatttttg agcgagaaca tttcgttttt tcaaaaggac tgttagaata
    13381 agcaagaaca agggggaaga cgtatgataa tcagtgaatt tgaccgtaat aatccagtat
    13441 tgaaagatca gctttctgat ttactgagac tgacttggcc ggaagaatat ggagacagct
    13501 cggcagaaga agtagaagaa atgatgaatc cagaacgaat cgcggtagca gcggtagacc
    13561 aagatgagtt agtaggattt attggtgcaa tccctcaata cggtatcaca ggttgggaat
    13621 tgcatccatt agttgtagaa agctcccgac gaaagaacca aataggtact cgattagtca
    13681 attacttaga aaaagaagta gcttccagag gaggaatcac gatttattta ggtacggatg
    13741 atttagacca tggaacaacg ttaagtcaaa cggacctgta tgagcataca tttgataaag
    13801 tggcttccat ccagaacctt cgtgaacatc cgtatgaatt ctatgaaaaa ttaggttata
    13861 aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa accggatatt tggatggcaa
    13921 aaacgattat tcctcgacca aattctcaat aataaaaaga ggttgtgaca gaagtaatca
    13981 gcttcaagaa ataagaagga atttacgaaa attacttctt gaatttttgt gaaattccaa
    14041 cttatttccg aagaagctac ttttggaaca ccgtgtacca gaggttgtga aaaagtcgct
    14101 tagtttcgag tagtaagaaa aattttgtga aaatggcttt ctacattttt gcataaattt
    14161 ggcttaatac cgagaaactg gcttttgaac accgtttatt cagataaggg actgtgacaa
    14221 gacttttgtc acagtttctt tttgtttatt cttttttatc tttgtatggc aataatagac
    14281 aatataacga aaattattta atggcttttg gaagaccatg gaaaaccttg tacaaagcta
    14341 ttttttctga aaaattcctt gaaacctcac gaaaaaatca ttattttatg aaaaagacaa
    14401 aaaaaagtgt tgatttttta ataattattc attaaactct taaacaactt cagaaaatat
    14461 taattattct gaaaattcca ataaaggggt acgtaaaatg aaaaagaaat ttacatttgg
    14521 tttggttgcg gtatgcggcc ttgtacttgc tggatgttat ggcggcagtt cagccacaag
    14581 cagtagttca gcaaaaagcg gttcagcaga tggaggaggc gtatttaact tagtcgtgcc
    14641 tcaagaaatg cctacagctg acttatcagt tgcaacagat acaatcagtt ttacagcatt
    14701 gaataacgtt tatgaaggaa tttaccgtct tgatgaagac agcaaaccac agccggcagg
    14761 agctagcgag ttggcagaag tcagtgaaga cggattaact tacaaaatca aattacgaga
    14821 agacgcaaaa tggtcaaatg gtgatcctgt tacagcagcg gattacgttt atggctggca
    14881 acgaacagta gacccagcta cagcttctga atatgcttac ctgtatgcgc cagttgaaaa
    14941 tgcagaagac attacagctg gaaagaaaga taaatcagaa ctagggatca aagcagttgg
    15001 tgactatgaa ttagaaatca aattgacgaa acaaacacca tatttccaat atctgcttgc
    15061 tttcccatca tttttcccac aaaaacaatc cgtagtggaa gaaaatgggg atgcctatgc
    15121 atctgcaagt gataaagctg tttataatgg accattcaca ttagaagatt ttgatggacc
    15181 aggaacagat acagaatgga cttataagaa aaatgatcat tactgggaca aagatacagt
    15241 aaaactttct gaaatcaaag tcagtgtagt aaaagaatct tctactgcat tgaacttatt
    15301 caaagatggc caagcagatg acgtgatctt gtctggtgag ttagcacagc aaaacgcaaa
    15361 cgatccagct tatacttctg ttaaagaagc gcggacaagc tatatcgaat tcaatcaacg
    15421 tgaaaagaat tcaccattca acaatgtgaa cctaagaaaa gctatttctt attctatcga
    15481 tcgtgaagct ttagtaaaac aagtactagg tgacggatca gttgtctcta caggattgat
    15541 cccatcagat atggtaaaaa gtccaacaac gaacgaagac tttgcaaaag aagctggaaa
    15601 attagtttct tatgacaaag ataaagcaaa agaatattgg gaaaaagcga aaaaagaatt
    15661 gggcgttgat tctttagaat ttgatttgat ggcttctgat gatgattcat cgaaaaaagt
    15721 aatcgaatat gttcaaaact caatccaaga aaacttggat ggcgtaacag tcaaaccaac
    15781 acctgttcca ttctctgtac gtcttgaccg ctcaacttcg ggtgattttg acgcagtact
    15841 aggcggatgg gctgctgact atgcagaccc aagcagcttt actgatttgt ttgtcacagg
    15901 taattcatac aaccgtggtc gctggagcaa tgcagaatat gacgaagcag ttaaagcagc
    15961 ttcatcaaca gacgctggcg atgaacaagc ccgttgggat gatttccaaa aagcaatcaa
    16021 gatcatctct gatgatatgg gtgtcgttcc ggtgtaccaa aaagcagaag gtcacctagt
    16081 gaatgaaaaa atcaaaggta tcgttcacca tgcggcaggc gcttcatggg attacaaatg
    16141 gacatacgtt gaagaataat cgttaatacc gtgagcatga gaaaaaacga ggctgcggca
    16201 aatgtcgcaa cctcgttctc atattcactt atcctaacaa agaaaaaagc atgaaaatag
    16261 cagaaagagc aattagtatt ccggcaatga tcagccaaaa gctgtacata ccgtagctgg
    16321 cagacgagag cgaggaaaat tctggttttt tctttcggtt ccttgttcgt gcaagatgga
    16381 ccgatcgctg aaaatgatcg aagaaacccg aagaaaagac ccataaaaaa ccgccgataa
    16441 tcagaaacgg caatgaccat aagaatagat cattagataa ttgaatgagt gtaaaggaat
    16501 ggttgatgag attttttatt aaaataacca gaatcagtag aaaagctact gcgtagggga
    16561 tagatttttt tttcatttga ttgctccttt atttttggtt cattatctaa taatgtagcg
    16621 aaacatctgt cagaagtcaa aagctagggg gaaacattag tgaatagtta tatcaaatat
    16681 gtattaaaac gtgtcttttt catgatcatc acgctttggt taattgcaac aatcaccttt
    16741 ttcttgatgc aattgctgcc gggcacgcca tatacgaatc aggaacgttt gagtcctgaa
    16801 acaatcgaga tgctaaataa acaagtcggt ttggataaac cagttatcgt acaatatggg
    16861 atttatcttt ctaatttgct tcaaggagat tttggaattt ccttccaatt taaaaaccag
    16921 ccagtcgcac atttgttagc tggaagaatc ggaccatcct tgcagttagg gttacaggca
    16981 attatctttg gaacagtcct agggacgatt ttaggaacga tctctgccat gaagcaaaat
    17041 acatgggcag atacatcttc tacactcgta gcgatattag gtcgttccat tccaaacttt
    17101 gtatttgctg ttttattaca atatatcttt gcaatcaaat tacaagtttt gccaatcgca
    17161 aaatgggatg gctttgtgta cacaatctta ccaacaattg cgttggccat gtcgccgctt
    17221 gctgactctg ctcggtttat ccgtacggaa atggtggaag tactgcatag tgattatgtg
    17281 gaattagcaa aagcaaaagg attgagccgt tgggaaatcg cctttaaaca tggtcttcga
    17341 aatagtttga ttccattgat gactttatta ggaccgttag ctgtagcatt gatgaccgga
    17401 tcactggtgg tagaaaatat ctttgctatt cctggtatcg gggaacaatt cgttaagtca
    17461 atcacaacaa atgattatcc tacgatcatg gctgtaacga tcctttactc atttatgctg
    17521 atttttgtta ttttgatcgt ggatctattg tacggtctag ttgatccaag aattcgtgtt
    17581 tcagaaggga gccgaggata aatggaaatg ataccaaagc gttatgaaac agttgcagat
    17641 atccctgcgg atgaatttct tccattacaa aaaaataccg aagaagaacg tgaacagatt
    17701 actgcacctt ctttgaattt tatccaagat tcatggcgcc gtttaaagaa aaacaaagct
    17761 gccgttattt caatggtttt actattggtc atcattttga tctctgtgat cacaatcttt
    17821 gtttctcctc atgatccaac tgcccaaaac gtggcttata tcaatttgcc tcctcgtatt
    17881 ccgggaatca atatcgatgg attgaatgga aaagcaatgg ttggtggtga acttgttgat
    17941 aaatatgctc aagcaaacgt cccttcaaac gtaaatttct ttttaggaac agacggtttg
    18001 ggacgtgatg tattaagccg cttatttatg ggaatgagaa tctcgttgct gatcgcattt
    18061 attgctgcat tactagatgt aacgattggt gtagcttacg ggttggtttc tggtttgtta
    18121 ggcggacgtg tcgataacgt gatgcaacgt tttttggaaa tcttatcagg aattccaaac
    18181 ctcgttgtca tgattttgat gttggtcgtt tttgaaccag gaattttttc aatcgtggct
    18241 gctatggcca tcacaaactg gataccaatg gcacgtatcg ttcgtgcaca aacaatgaaa
    18301 ttaaaagatc aagaatatgt tttagctgga ttgacattag gtgaatcaag aatgaaaatt
    18361 gcattcaaac atattttgcc gaatatctct agtgtcatta ttattcaaat gatgtttagt
    18421 attccatctg ctattttctt cgaagccttt ttaagcttta tcggtttagg tcttacgcct
    18481 ccgtcagctt cattaggaac gatgttgagc gaagggtaca agacattcct gtatctgcct
    18541 tatctattat ggattccggc agtaacttta tcggttatca tgattggctt taacttactt
    18601 gctgatggat tgcgtgatgc ctttgatcct aaaatgaaag agtgaagacg atgacgaaaa
    18661 ttttagaagt gaaagactta gaaatctctt ttgatacgta tgctggaaag gtacgagcga
    18721 ttcgcggtgt caattttcat ttgaataaag gagaaacatt ggcgatcgtt ggggaatctg
    18781 gaagtggaaa atcagtgacg accagaagca tcatgcgctt gctgtcaagc aacgccaata
    18841 tagatgctgg tcaaatcctc tttaaaggta acgatatcgt tggaaaatca gaaagagaga
    18901 tgcaaaaaat ccgtggtaaa gaaatagcga tgattttcca agatccaatg acctctttag
    18961 atccgacgat gcccattggg aagcaagtcg ctgagtccct tagaaagcat aataaagttt
    19021 caaaaaaaga gggacaaaaa gctgcattag aattgcttaa attagttgga atacccgaag
    19081 ctgagaaacg tatcaacagt tatccgcatc agttctcagg aggtcagcgt caacggatcg
    19141 tgatcgcgat tgcactggta tgttatccgg aaatcctgat tgctgatgaa cctacaacag
    19201 cgcttgatgt gactattcaa gcacagattt tggagctgct gaaagaaatt cagacaaaaa
    19261 tcgatacatc aattatcttt atcactcatg accttggtgt agtagcgaat gtcgctgatc
    19321 gtgtcgctgt catgtatgga ggaagaatcg ttgaagttgg aacatcggaa gaaattttct
    19381 acaacccgca acatccctat acttggggac tgcttggttc aatgccgaca ttagatagtg
    19441 cgaacgatcg attgtatgct attcctggtt ctccaccgga tttattgaac ccgccaaaag
    19501 gagacgcatt ctatccaaga aatgaattcg cgatgaaaat cgatgcagaa caagaaccac
    19561 cattttttga actatcaaaa acacacaagg cagcaacttg gctacttgct ccgcaggcac
    19621 ccaaagtgac accgccagaa gaaatccaac gtcgctgggc tatctttaaa gagaaacaaa
    19681 aacatactta cggtcaagga ggaattgctg atgccaaata aactacttga agttaaagga
    19741 ttgaaacagt atttcaatgt aggaaaaaag aatgaagtac atgctgtaaa tgacatcagc
    19801 tttcacattt atgaaggaga aacattcggt ttagttggag aatctggaag cggaaaatcc
    19861 actactggcc gtacgatcat tcgcttgaat gaacctactg atggtgagat attattcgac
    19921 ggtcaagata taacgaagat caaagataaa aaaggtttga cgaaattccg gcatgatgtt
    19981 cagatgatct ttcaagatcc atacgcttcg ttgaatcctc gtatgaaagt cagagatatc
    20041 attgccgaag gaattgatgt taatggacta gctaaatcat ctgaagagcg tgcaaaaaaa
    20101 gtcgatgatc tattgagaac tgttggattg aatccaagcc acggtactcg ttatcctcat
    20161 gaattttcag gtgggcaacg ccagcgtatt ggtattgcac gagcattggc agtaaaaccg
    20221 cgttttatca tttgtgatga accaatttct gcactagatg tgtcgatcca agcccaagtg
    20281 gtcaatttgt tgcaagatct ccaaaaagaa catcaattga cctatctatt tattgcacat
    20341 gatttgtcga tggttaaaca tattagtgac cgaatcggtg taatgcataa cggcttgtta
    20401 ttagagatgg gaacaagtga tgaaatctat aatcacggtg ttcatcctta tacagaaagt
    20461 ttgttatctg ctattcctct accagatcca gaccatgaga gaaaacgcag aagaatcaaa
    20521 tatcaacctg aaccagatga cggacaagta cgtcaacttc gtgaaatcgc accagaacat
    20581 tttgtctatg caactgagca ggaagtccca tattacgcaa aaaaactaaa acgacaaaag
    20641 gaatctcttc tggttgctaa ctaggaggga catagatgct aaaagctttt aaattccgta
    20701 tgtatccgac agaagaacaa aaacagcaat tgattcgtac ttttggatgt gctcgattta
    20761 cctataacca tttgctgaaa aagcggcaga aaagttggca acaaacagga gtagccaatt
    20821 tttcgctcac acccgctaca ttaaaaaaag aatacccatt cttaaaagaa gtagacagtc
    20881 ttgctttagc aaatgcacag cttaatttgg atcgggcttt tcgcaattat ttcaagggac
    20941 gtgccagctt cccaaagctt aaaacgaaaa aaagtatgtg gcaatcttat acgaccaaca
    21001 accaaacccg tacgatctat ctggaaaatg gctacttaaa gttaccaaaa caaaaagaac
    21061 taatcaagat aaatcagcat cggccagttg aaggatcgat tcgctccgct acgatttctg
    21121 ctcgatataa tgaagaattt tatgtcgcac tactttgtga tgtttcgcca gtaaaaaaag
    21181 aatctttagc taaatggatc gggatcgcct atcatccgaa gacattgatc caaacatctc
    21241 gacctctaga agtaacttta ccaaaatttc accagacaga agaaaagctg caacatgcac
    21301 agcggaaatt gaatgtgaaa gtccgctccg ctcaccatag aaagatcagg ttagatcagg
    21361 caagcaatta tcagaaacaa aagagaaaag taatggatct ttatctgaaa caaaagaacc
    21421 agcgagaaga ttatcttgaa caattatctg ggaaattggt caaacaatat gactacttat
    21481 ttgtagaatc ttttccaaaa gaagaggcac atgctgattt ttctattcac gactggcata
    21541 aattaataac aaaattgcgt tataagtccc aatggtataa taaaaaattt cttttgatca
    21601 ataccgacgg agcagaagaa agcaattccg taagaaagag ccaagtagta gaaaaaatgg
    21661 gcagacattc ggttatcaag ggataaaaaa tgaatgaaac tgataggagc gttagggtta
    21721 gccttgttaa taaaaagtct taatgacttt tgtttctagg aatttttctt ttgaagaaaa
    21781 gctcactaat tatgacaaac caataaaaca atagcagaaa aagttcgtac gagctttttc
    21841 tgctattgtt aattttttat tcagaaagtt tacgaataca tcaaaattct gaaacaaaaa
    21901 acgtaactca caaagagttg tttttgcgtt ttttcttgaa tgattaggtc tgaatctttt
    21961 gctcacaacc ttattcatgg tgccccggct tgagctgata gatttttgaa ggacggccga
    22021 ttcctacagg acgttcaccg atctcatcga aatattggag catagctttc ttaaaattgg
    22081 aatgatcgat cgttttataa tcgatcccta agaatttagc aaatactttt cgagcttccg
    22141 taatcgtgaa atctttacct aaaacttgta gaacttgcgg ctcgtgttcc attttattga
    22201 ctacacggtt gaatgctttc aagatgattt gactatggtc aaaagccaaa gtatctttgc
    22261 cagaagactc tccagtgact aaatcaagcg agatagccac ttctccgcta gataaatgga
    22321 tcttgttact atgacgttct agtgtgaacc agcgtacttc cttggcatca tctccggcga
    22381 ttagcggttc ttctccaata aaggctaagt agctgactgt gacgacccag cctcgcggat
    22441 ctcgattagg cgtactgaat gtatgcagtt gctcaatatt ttcttttgaa ataaccacac
    22501 cagtttcttc ctttgtttct cttaagacgc tttctccagt tgactcatcc ttttggacaa
    22561 agccaccagg caatgcccat gaatttcgat aaggatgccc ttttctttgg atcaacaaaa
    22621 ctttcagctg atcttcttct ttgttatagc acatcagtac gatatcgaca gtcaaagagg
    22681 gcttgtcata ttctggacgt tcctgttttt gataccagtt aagaaattct tcttcacttg
    22741 ctttatgttc ataatataat ttttcttctt ctttagaagc aaaacggttc atctgaccac
    22801 ctccattgac agtaaaagta ctttttacct tattgtagca gactctgaaa aaaaaccaag
    22861 gatttacttg aaaaatctag gttatcattt aaatatgaaa aataaatgga agtatgagat
    22921 tgaataaaaa gaaaagcaga taaaacggca atactttata ccgctcttca cgaatggcaa
    22981 agaagccaca aataacgata tatacgtcaa tgataaaacg caaaatccaa gctgctgtca
    23041 taaaactgtt caaatgccca tggaggttaa aataaccata catacgaata taaaaatagc
    23101 tgaatattaa atgtgctaat gaaagaaaag caatactaag tgtaaaaaaa agatgtttct
    23161 tctgcatgat tgttccagtc ccttactaag atagatagtc tttattatac cacgtgtgag
    23221 gggagaaata aaaagccgtt ttttagtaga tatgaaacaa aacaaaaacc cgcatttatt
    23281 caacctattc atccttttaa aggatagatt gaacgtagat agaagtcgtt tatccagtct
    23341 ttttcatttt gaaaaaaagc taacagcatg ctttttttat ggtatactag caaggaaacg
    23401 aattcgcatc atgcgataaa ggaggaagag ccccgtggca gaaaaggaaa ctttttatat
    23461 cactacgcca atctattatc caagcggcaa acttcatatc ggcaactcgt atactacgat
    23521 tgcatgtgac gcaattgctc gttataaacg gttgatgggc tttgatgtgt tttatctcac
    23581 tggagtggat gaacatggtc aaaaaatcga aacaaaagca gaagaactag gtgtaaaacc
    23641 gcaagaatat gtagataaaa tggcggctga tgtcaagaaa ttatggaaaa cgcttgatat
    23701 cagttatgat aaattcattc gcacgacaga tgattaccat aaagcagctg ttcaaaaaat
    23761 atttgatcgt ttattagaac agggagatat ttacttaggt gaatatgaag gctggtactc
    23821 tgtttctgac gaagaattct ttacagaaac acaacttgca gaagtgtaca aagatgacga
    23881 aggtaacgtg atcggtggta aagcgccaag tggacacgaa gtagaattgg taaaagaaga
    23941 atcatacttc ttccgcatga gcaaatacgc agaccgtcta ttggaatact atgaagaaca
    24001 tcccgaattc atccagccag aatctcgtaa aaacgaaatg atcaacaact ttatcaaacc
    24061 aggattagag gatcttgcag tttcacgaac aacttttact tggggagtac cagtcaagag
    24121 tgatccgaaa catgtggtgt atgtatggat cgatgcatta tccaattata ttactgcact
    24181 aggatatggc tccgaagatg aaagtctatt cgaaaaatac tggcctgcag atgttcagat
    24241 ggtcggtaaa gaaatcgttc gctttcatac gatctattgg ccaatcatgc tgatggccct
    24301 tgatttgcct ctacctaaaa aagtatttgg gcatggctgg ctattgatga aagacggaaa
    24361 aatgtctaaa tcaaaaggaa atgtcgttta tcctgaaatg cttgtggaac gttatggttt
    24421 agatgcactc cgttattatt tgcttcgtgc tgttccgttt gggtcagatg gtgtctttac
    24481 gccagaagat tttgtttccc gtgtcaatta tgatctggca aatgatctag ggaacttatt
    24541 gaatcgaacg attgctatga tcaacaaata ttgtgatgga ctcgttcctg actatgcctc
    24601 acttgtcact ccatttgata gtgaactgtc tacgacggct gctaacgttg tcggacgtta
    24661 ccatgatgca atggaaaaaa tggaattcaa tacagcattg gctgaaatct gggtgctgat
    24721 ttctcgtgca aacaaataca ttgatgaaac agaaccatgg gtattagcaa aagacgaaga
    24781 aaagaaagct gaattgaata gtgtcatgat ccatttagct gaatctttgc gtatcgcagc
    24841 gatattactt cagccaatca tgacagaaac gccagagaag atcttcaatc aactaggatt
    24901 ggactctgaa acaatgaatc ttgaaggatt acactttggc gaatttcctt caggaacaaa
    24961 agtagttgca aaaggtacac caatcttccc acgtttagat atggaagaag aagttgcttt
    25021 tattcaagaa aaaatgtctg aaggtactca aacaaacgaa gatacagtca aatgggatcc
    25081 agaagaaaca gaacttgttt caacgaaaga aaaacaaatc aaatttgatg tatttgaaaa
    25141 agtagaacta aaagtagcag aagtcatcaa ctgtcaaaaa gtagaagggg cagataagtt
    25201 gctgcaattc cgactagatg ctggagacag ccaagaccgt caaatcttgt caggaatcgc
    25261 tgaattttat cctgatccaa gcgaattgat cgggaaaaaa gtcgtcattg tagcaaatct
    25321 gaaaccacga aagatgcgtg gacaaatcag tcaaggaatg atcctttctg cagaagcacc
    25381 agatggctct ttacaagtaa tcgaagcacc aaaatccatg ccaaatggct cagaaatcgc
    25441 atagaaattc aaagggggta tgacactagt tgtgtcatac cccctttttc cgaaatttga
    25501 gaagcaattt tcgtaaattc cttcttatta cttgaagcca atcatataat acagaaacag
    25561 agaactatcc aaaataaatc ctagaaaaag aagtacgagc ttcgctgatt tttgttaatt
    25621 tagaataata ctaataggaa tcgtaaaaac agaaaaaaag cataatgata aagggtcggg
    25681 cagattttaa ttgattcatc tggtactctt ttttattgtc cttacattca taaagtttga
    25741 atgcaatgac tttattacat ctatatttat atctaacagt agcgttgatg tgttaattat
    25801 aagttctatc actttatgtt caattagttt gtgctcttat atgtgtgatt gaaaatatag
    25861 ataaaaaaac aatcatcggc tttgacttcg atgattgttt tctttatttt gtaaaaatcc
    25921 tatcacttga ttttatggta accttttatt tttgtcttca aacggcttgg taagagagca
    25981 gtaagcagtg caaatgggat cgaaaagaca taccagaaaa tcgtacgtcc gataccataa
    26041 tgttgataga gctttgtcaa catcacgtgt aacaagatca accctaaaag caaggagcca
    26101 gctataaacc aatgattatc ccaatgcatg acttcactaa gtgccatcac tccaaaagga
    26161 tagaaataaa aatagatccc gactaaggtc atccgccagt tctttgtaaa tgttccgata
    26221 ttcaataaaa agaaaatcgc tgaaagcaaa ataccgatag gcggaaaaag cccaaccaaa
    26281 aaggaataca acatccccca caagatcatc acaggacctt tgatcaatgc aacgattgcg
    26341 atgaacaaag tcagcaatat tagtttttgt gataacgttg caacagtcat taatccaaat
    26401 aaaattaatg tgaaccaatg ccaatgggac tgctgttgtt ctttacggga aaaatcgacc
    26461 cggttggata aataatctgc taatttcgga taagaacgct taaaatccat aaactgttcc
    26521 tccttcgtgg aaaaggtagg tttagtatac gaaaaataaa aaagaaatac atccgtctta
    26581 agagggagtt tttcactgaa agtggagaaa aaagaatggt aaattaaaat attctcagtt
    26641 atactgaaaa ttataccaaa tttcaaagaa gaaagaggat gggaatgaaa ggcaaactaa
    26701 aacgagaaat caatctgttt ggcgcattag ctaccgttat gggaaccgtg atcggtgcag
    26761 gcgtcttctt caaaactgct gctgttactg ctagtactca gtctacaagt ttgacattgc
    26821 tagcttggct tttgggtggt ttcttaacga tctgtgctgg attgacagtg gctgaattag
    26881 ctacagcaat cccggaaact ggtggagctg taaaatatat tgaagctgcg tatggaaaat
    26941 tgcccagctt tttattagga tgggcgcaaa gcttgattta ctttcctgct aatattgctg
    27001 cattatcgat tatctttgcg acacaattga cgaacttatt acaattatct accgattatc
    27061 ttttgttgat tgcagtgatc accgctgttt ctgtgacagg gttgaatttg ttagggacaa
    27121 aagtcggtgc ttctgtacaa tcagtgacgt tgattgttaa attaatacca attgctgtga
    27181 ttgtcatatg gggattattg accccaggac aaggaactgt ccagttattt ccaatcgaag
    27241 ctggaaaaga tgttactttt gtcgaaggat tgagcagtgc gttgttagca acgttgtttg
    27301 cttatgacgg ctggttaggt gtcggtgcaa tggcagggga aatgaaacgg ccggaaaaag
    27361 atttgcctaa agcaattatt cttggtttga gttttgtaac agtcgtttat ctattgatca
    27421 attttgtttt tttgaaaact ttgccgattg atcatcttgc cggtaatttg aatgcagctt
    27481 ctgaagcatc agacgtcatt tttggaggaa tcggtggaaa gctggtcact attgggatct
    27541 tgatctcggt atacggtgca ttgaacggtt atacactaac tgggatccgc gtgccttatg
    27601 cgatggcttt agaagacgag ctacctttca gtaaacagct gacaaagctt tcaaagaagt
    27661 ttacggttcc ttatgttcct gcggttttcc agttagcagt agcttgtatt atgatgagcc
    27721 ttggttcttt cgacttttta acagacatgt tgatttttgt gatgtggcta ttcagtttac
    27781 tgatttttat cggtgtcttt attttaagaa aaaaagcgcc ggaattgcca cgtccatata
    27841 aagtaccact ttatccaatc gttccgatta ttgcgattct cggtgctatt ttcattttag
    27901 gtatgacgat gatgacgcaa acgaaattag cattgatcgg tataggtgtt accttgatag
    27961 gtatcccagt ctattatcaa aaaaagaaaa aacgctcaga agagtaaaat atttcaacaa
    28021 cagacagaaa aagtacgaac taggtcctct agatcttcgt gctttttcta tttcaataaa
    28081 acaagttctt ctattttgat ttttgctact tctgcaagta gtgcttatgt gctaaagtaa
    28141 gaatgaaaag gagagataaa catgatattt gattctcata cccatttaaa tgctgaacag
    28201 ttcaatgaag atattccaga aacgattcag cgagcacaag aaatgggggt aacgaaaatg
    28261 gcggtcgtgg gcttcgatac gccaacgatt gaaaagtctt tgcaattaag ccatgactat
    28321 ccaaatatat acagtattat cggctggcat ccgacagagg ctggcagtta tacgaaagaa
    28381 atcgaaaata aattacaaga acaattgact ttaccaaagg ttgtagcatt aggggaaatt
    28441 ggcttggatt atcattggat ggaagacccg aaagaagtcc aagataaagt atttcgcaga
    28501 cagattgcta tcgcaaaaga aatgaaccta ccaatcagta ttcatactag agaagcactt
    28561 gaagacacgt atcaaatcct aaaagaagaa gatgttcgag atatcggtgg aatcatgcat
    28621 agtttcagtg gtgattatga atgggcaaaa cgatttcttg acttagggat gcatatttca
    28681 tttagcggtg tcgtcacttt caaaaaagca ttagacgtcc aagaggctgc agcaaatgta
    28741 ccaatcgaac gattacttgt ggaaacagat gccccttatc tggcaccagt tccttttaga
    28801 ggaaagcgaa atgaaccagg ctatactcgt tatacagtag aaaagattgc tgaacttcgg
    28861 aatcttccga cagaagaagt ggctgcccaa acatggacaa atgcgcaccg attatttggt
    28921 ctaagcgaac atggataaga tgaagatcca agagattata gtcgttgaag gaaaagacga
    28981 tacaagaagg ctgcgggaag tagttgatgc agatacgata gaaacaatag ggtctgcaat
    29041 caatgaagag atcctgatgc aaattgaaca tgcccaagag actcgtggag tgatcgtttt
    29101 taccgatcct gatttttcag gagaaaaaat aagaaaaatc attatggaag ctgttcctca
    29161 ggcaaaacat gcttttttgc cgcgcacaca agctaaacca aagaaaaagg gaagccttgg
    29221 tgtcgagcat gcaagtgatg ctgctatttt agaagcattg aaaaaggtcg tgacgccaga
    29281 catttcccaa acggctgttt ctgaaatcac tagacaagac cttttagact atggtttaat
    29341 agctggggca caagcaaaag aaaaacgaga aaaactaggt gacgagttgc gcatcggtta
    29401 cacgaacggc aaacaattgg aaaaacgttt gaagatgttt cgtattacgc cgaaagaact
    29461 cgcccaagca atgaaaatag tggaggaaca acatgagtga atatcgtgaa attgcgacac
    29521 cctctagaac aaaagagatt ttattgaaac atggtttttc atttaaaaaa agtttaggac
    29581 aaaattttct gactgaacca aatattttaa ggaaaatcgt agaaactgcg caaatagatg
    29641 aacatacgaa cgtgatcgaa gttggaccag gaatcggtgc attgacggaa caattagcca
    29701 agcatgcaaa acaagtcgta gcatttgaga tcgatgatcg tttgatccct gtattggctg
    29761 atacgatgca accctatgac aatgtgacta ttgtacatca agatatttta aagaccgatt
    29821 tgtcaacagc tgttagagaa acatttcatg aggagcttcc gttaaaagtc gtagcgaatt
    29881 taccttacta tattacgaca ccgatcatga tgcattttct tgaatcagat ttggttgtgg
    29941 atgaactagt cgtcatgatg caaaaagaag tagctgatcg tatctctgct gaaccaggaa
    30001 cgaaagctta tggttcatta tcgattgctg ttcaatatta tatggaagcc agtttagcat
    30061 tcatcgtacc aaaaacagta tttgtccctc agccaaatgt agattcagcg attttgaaac
    30121 tgacaagaag agatataccg gcagtcgaag tgacagacga aaaagcattt ttccgattga
    30181 caaaagcggc atttcagcaa agaagaaaaa cgctttggaa taacttgcag cattcgtatg
    30241 gcaaagatga ccagacaaaa gcatggttag caaaaagctt ggaaacagct ggaatcgatc
    30301 caaaacgtcg tggggagact ttgtcattac aagaattcgc cgcattaagc aatgcgatgt
    30361 cagaaaatat gcagtaaaaa aagaggttgt gacagaagtt gtgaaaaagc tgtcctgcat
    30421 caagtaataa gaacagccaa acaaaaatag ttcctcatgt ttttcgtttg tttgggctta
    30481 ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga ggttgtgggc ctgccgttta
    30541 actctaagtc acaaggaaca atttcaaaaa acagcttctc atgtttttga gttagttggt
    30601 cttattactt gatgcaagct tttgaccact attatgccga acaaggagat gtgacacaaa
    30661 ttttgtcaca tctcctattt ttgtttcttg atcaaaaaat tcttatactt gatactcaca
    30721 ctcattttgt atggatttag aaaagaatat gtgtcttgac agttattagt aagtgagtta
    30781 tactaagtcg acatttatgt gtcaagacat attaggagag agaaaaaatg agaaaaaatt
    30841 cagttcgaaa actaacgatt tctgctttat tgattgggat gggggtcatt atcccaatgg
    30901 tcatgcctaa aatcatgatt ccaccagctt cctttacttt ggcgtctcat gtgccattat
    30961 ttattgcgat gttttttaca ccaggagttg cagtggctgt tgcgctaggt acgacatttg
    31021 gtttcttttt aacaacgccg gttatcatcg cattgcgagc attgtcacat cttgtgtttg
    31081 cgttgattgg ggcttggtac ttgcaaaagc atccgagtat cgttttaaaa aatggacagt
    31141 ttacttttgc taattggcgt ttccaagggt tcaattttgt gatcggtgtg attcattctt
    31201 tagcagaaat gctagtagtc agcatctttt actttattgg taatatgcct gaaacatatt
    31261 attctcaagg atatttttat acagtattca tcttgatggg gattggtggg cttatccaca
    31321 gtttagttga ttataatatt gcttatttta tagcaggaac actcagcaaa tattttgata
    31381 tccccgtatt tacggcagca aaaaaagaaa atcggaaaga gtcgattcaa gggtacgcga
    31441 agaaaacgac atattagaca tgatctctca aaaaaaaaac tctcatctag taatggataa
    31501 taaatcctct aagatgagag ttttttgtcc taaaaagagc tgcaccaaca tcttctggca
    31561 cagctctaac agggggcaat ttatggaagt ttgatgactt gttctgtttc tttatcaaag
    31621 aagtggcctt tgctgatgtt gaaggcaagg tcgactattt cgcctggttt atggaaatct
    31681 cttgcatcta cttttgagat gaactcagta gaaccagttt ttgtgtaaag catcgtttca
    31741 gctccaagta attcggaaac gacaacttct gatttcacta cggcttcagg tgaagcttca
    31801 agggctactt gttcactgtg gatgtcttct ggacgaatac cgaagataac ttcttttcct
    31861 tcataacctt tttcaactaa tactttgttt tttccttcag gaatacgaag cttaagccca
    31921 tgtccatctg tgataacacc atttttcaat gtcacattaa agaagttcat ggcaggagat
    31981 ccaataaagc cggcaacgaa catattgacg ggtgtatcat aaacttcttt cggtgtaccg
    32041 atttgttgga taaatccgtc tttcatgata acgattcggt cagccatagt cattgcttct
    32101 gtctgatcgt gagtaacata gatggtcgtt gtttcaagac gctggtgaag tttggcaatc
    32161 tcagcacgca tggctacacg taatttagca tctaaatttg ataatggctc atccattaag
    32221 aagacttttg catcccgaac gattgcccgt cccaatgcca cacgttggcg ttgtccacca
    32281 gataaagcag ctggttttcg tttcaagtat tctgtcagac ctaagatctc tgctgcattg
    32341 tccacacgtt ttttgatgtc tgctttatca tatttacgta atttcaagcc aaaagccata
    32401 ttatcaaaaa cagtcatatg aggatacaat gcgtagtttt ggaaaaccat ggcaatatca
    32461 cggtctttag gtgccacgtc attcatgact tttccgccga tatttagttc tccttcagag
    32521 atatcttcca gtcccgcgat cattcgcaaa gtagttgact ttccacaacc ggaaggacca
    32581 acaaaaacga taaattcacg gtctttgatt gatagattaa aatcagttac agaataattt
    32641 tctgcattgt catatttttt atatacgttt ttcagagcca tttctaccat aatacgttcc
    32701 acactttctt ttttagtttt attaactatt taaagtataa atgaaagcgt taactaactt
    32761 caatgtcatg ttgaacaaga attttttctt ttttttgtca atgtgctagt tttaagcttt
    32821 aataaatatc cataagaaat aaaaactgat acactggagt aaataagtat gttaacaata
    32881 tcaaaaggag tgtctcttat gaaaatcgct ttgatcgctc atgaccgaaa aaaacctatg
    32941 atggtgaaat tagcaacagc gtataaaaca atattggaaa aacatgaact ttttgctacc
    33001 gggacgactg ggcagaggat cacggaagca accggcttgc cgatccatcg gtttaaatcc
    33061 ggaccgttag gcggggatca gcaaattgga gccatgattt cggaggatca gttagatttg
    33121 gtgatttttc ttcgagaccc gctggctgca cagccccatg aaccagatgt aacagcactt
    33181 atccgtttat ctgatgtcta tgagattccg ttagctacga atatcggaac agctgaggtg
    33241 ctactaagag gactggaagc cggcttccta gattttcgaa gaatcgtcca tgaaatagac
    33301 aagcatccac tttcattttg atggataagc gtatggaaaa ataacgttta atgttcgcct
    33361 atatgtagct ataaaagcta aacaaactga taatatgcga tataatacga acgtattgga
    33421 taatataaac aataatatta gtttttcgta tttgcagtaa atgtgaaaat atgctatagt
    33481 ttctgtggga aaagatccca aaaataatac agagtagaaa ataaagcgtt aagtgctaag
    33541 aggatgggat gttgcctctt ggacgaagga cgtaatgttc gcggttttat tttcgcattc
    33601 gctgcatgat acgatgtagc agctcttaaa ggagatgcta aaaatgaaga aacaccggtt
    33661 agacgcacgt atgattgcta ttatgggctt attgattgca ttgatggtca ctttgtcccg
    33721 actggtagca atcgagaccc catttattaa aatcagtgtc acatttattc cacaagtgat
    33781 catgggcatt ctttttggtc ctttttggtc agggataggc gcagttttag ctgatttagt
    33841 aggaatggcc ctcttctcga aatctgcatt ctttattgga tttacattga atgcatttat
    33901 tgaaggagca atctacggat tctttttcta tcgaaaagag atcacttgga aaaatgccat
    33961 tctggctacg cttagtgtca cgctgatcat caacttattt ttgacaccat tatggcttgc
    34021 gttgatgtac catgtgccat tgttcagctg ggtcgtttgg gcgccccgcc tgttaaaaac
    34081 agtaatatgg ttaccgattc aatcaattgc catttattac gtaggacgta gtattcctta
    34141 caaaaaaatt ttaagaagtt tagcgatcca cgctaaataa aaaa
//
LOCUS       DAPBBV010000030        34003 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.030, whole genome shotgun sequence.
ACCESSION   DAPBBV010000030 DAPBBV010000000
VERSION     DAPBBV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.030"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..839
                     /locus_tag="RD486_001793"
     CDS             <1..839
                     /locus_tag="RD486_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7663523.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
     gene            complement(1263..1433)
                     /locus_tag="RD486_001794"
     CDS             complement(1263..1433)
                     /locus_tag="RD486_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7663524.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1627..1806)
                     /locus_tag="RD486_001795"
     CDS             complement(1627..1806)
                     /locus_tag="RD486_001795"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663525.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            2193..3305
                     /locus_tag="RD486_001796"
     CDS             2193..3305
                     /locus_tag="RD486_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7663526.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3383..3676)
                     /locus_tag="RD486_001797"
     CDS             complement(3383..3676)
                     /locus_tag="RD486_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDT7663527.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3844..4158
                     /locus_tag="RD486_001798"
     CDS             3844..4158
                     /locus_tag="RD486_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HDT7663528.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4179..6158
                     /locus_tag="RD486_001799"
     CDS             4179..6158
                     /locus_tag="RD486_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7663529.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6171..6497
                     /locus_tag="RD486_001800"
     CDS             6171..6497
                     /locus_tag="RD486_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HDT7663530.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6513..7031
                     /locus_tag="RD486_001801"
     CDS             6513..7031
                     /locus_tag="RD486_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663531.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7031..8383
                     /gene="celB"
                     /locus_tag="RD486_001802"
     CDS             7031..8383
                     /gene="celB"
                     /locus_tag="RD486_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDT7663532.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8467..9972)
                     /locus_tag="RD486_001803"
     CDS             complement(8467..9972)
                     /locus_tag="RD486_001803"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HDT7663533.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10064..10654)
                     /locus_tag="RD486_001804"
     CDS             complement(10064..10654)
                     /locus_tag="RD486_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7663534.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10833..12479
                     /locus_tag="RD486_001805"
     CDS             10833..12479
                     /locus_tag="RD486_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7663535.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12528..13247
                     /locus_tag="RD486_001806"
     CDS             12528..13247
                     /locus_tag="RD486_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDT7663536.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13846..14793
                     /locus_tag="RD486_001807"
     CDS             13846..14793
                     /locus_tag="RD486_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7663537.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14805..15725
                     /locus_tag="RD486_001808"
     CDS             14805..15725
                     /locus_tag="RD486_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7663538.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15766..17223
                     /locus_tag="RD486_001809"
     CDS             15766..17223
                     /locus_tag="RD486_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7663539.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17568..18182
                     /locus_tag="RD486_001810"
     CDS             17568..18182
                     /locus_tag="RD486_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7663540.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18175..19899
                     /locus_tag="RD486_001811"
     CDS             18175..19899
                     /locus_tag="RD486_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7663541.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19896..21347
                     /locus_tag="RD486_001812"
     CDS             19896..21347
                     /locus_tag="RD486_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7663542.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21820..23973)
                     /locus_tag="RD486_001813"
     CDS             complement(21820..23973)
                     /locus_tag="RD486_001813"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HDT7663543.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23975..25021)
                     /locus_tag="RD486_001814"
     CDS             complement(23975..25021)
                     /locus_tag="RD486_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7663544.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            25171..26457
                     /locus_tag="RD486_001815"
     CDS             25171..26457
                     /locus_tag="RD486_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HDT7663545.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVE"
     gene            26473..29175
                     /locus_tag="RD486_001816"
     CDS             26473..29175
                     /locus_tag="RD486_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDT7663546.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            29160..30017
                     /locus_tag="RD486_001817"
     CDS             29160..30017
                     /locus_tag="RD486_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7663547.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30088..30987)
                     /locus_tag="RD486_001818"
     CDS             complement(30088..30987)
                     /locus_tag="RD486_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7663548.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            31156..33327
                     /locus_tag="RD486_001819"
     CDS             31156..33327
                     /locus_tag="RD486_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDT7663549.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33395..33736
                     /locus_tag="RD486_001820"
     CDS             33395..33736
                     /locus_tag="RD486_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7663550.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
BASE COUNT        11063 a         5947 c         6975 g        10018 t
ORIGIN      
        1 catatcagct ggtagaaact caagcgccaa cggggtatga attagatgcg acaccgatcg
       61 agtttgagat cgaaagaagt cagacagcgg tggtagaatt gacgaaagca aaccgactta
      121 caccaggcgg tgtcgtgttg acaaagatcg atgaccaaag cggggaagtc ctgcaaggag
      181 ctgtttttga gttacaagat gccaatggaa ccgttctgca gtcaggtcta accacaggag
      241 cagatggaaa actggcgatt gacggcttag caccaggagt gtatcagctg gtagaaaccc
      301 aagcgccaac ggggtatgaa ttggatgcga caccaatcga gtttgagatc gaaagaagtc
      361 agacagcggt ggtagaattg acgaaagaaa atcgacttac accaggcggt gtcgtgttga
      421 caaagatcga tgaccaaagc ggagaagtcc tgcaaggagc tgtttttgag ttacaagatg
      481 ccaatggaac cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgatag
      541 atggcttagc accaggagca tatcagctgg tagaaactca agcgccaacg gggtatgaat
      601 tggatgcgac accagtaact ttcaagatcg aaaaagaaca agaagtggcg atctttttaa
      661 caaaagagaa tagaaaagtt gctgatagct cagatataag aggaaacaat ccaacaagca
      721 gtggaaataa gcatcttcca aaaactggag aaaccatcat tagccagttt atattgtcaa
      781 tattgggtgt gctacttgtt ttcatcagta taaaatttag aaagaaacga aatatatgag
      841 ctaaaataaa aaattgaata agcatagttt ttaaaatcaa ctagtaccca tcaattgaat
      901 ggaaactacc gattttagaa ggggtataca aacaaatatt agtatcggag tagagaaggt
      961 tgaacccaac cagtaaataa gtaaagacaa ttttgtgctg cgttgagaag tgaaaaataa
     1021 acctttgtag taatactagt taataaaaaa tatacaaaaa cactgcgaaa atcattcttg
     1081 agtttcgcag tgttttttgc ctaatgactc aagtttattg ggtaatactt tgattttctt
     1141 tctacaaata atcagcgatc agttgtaatt ttttctctag ttttaatggc tctttgtcaa
     1201 taaggagaaa aacaagtcgg gtcttttgtc tcggaaagct tcaaccaact cgtgaataaa
     1261 ggttacgcct ccttgaaagg cgtggaaaaa ccaagtaatc gatcaatcac caatttcgca
     1321 tttggtagaa catgtttggt gagctgaaag taggtggcgt tcatgtctgt aactaagaat
     1381 tctatttctt taggattagt gcagctaagg aaatagtttg ttaatcgagg aattttttgt
     1441 gtaggtaaat tttctcgatt aatttttctg tctcgccatc cgcggaaata aaactcagtt
     1501 tatcctcaac ggaaacgtga gaacgaaatt cacaaccctc aacactcaag acagaattct
     1561 tttggaagac tttggtaaat agcttctcaa ctctttcaat gtgcgaataa cggttgtcaa
     1621 agatacctaa caacttttcg aaataaaaaa taacgacact ttttcagtca gtaaagaagt
     1681 gattttatgt ctgacatgat ttgaaatcga gtgccttgga cggataaaat aactttgagc
     1741 gttccaatgg cttcgacagt ttttacaggt atagcgctgc ttttttaggc gtataaccat
     1801 tggcatatga ttatattatt caaagtggac aatggtttcc ttcttcttgt ttttcaccac
     1861 cattaatttc ctatttccat ctaccacagc agaaccacaa tttctacaga cacatggagc
     1921 agggaagaga actgcagcaa cgatcaatgt ttttttcttc tgtaaggttt cgtaagagac
     1981 ctctgtaatc atcaaatttt tgtctattga tctcagaatt tttttgatag aaccattcat
     2041 aaagcatatc gttctctcag ttgtttattt tgtggtgatt taatcataca agaaaacgat
     2101 atgttttttt ataaaaacat gaataggaaa aatagttgac aagaaaatga caacgccata
     2161 tgatgttcca tagtatttac aacctgtcat agatgactgt aaaaaataaa agtaaaaaga
     2221 aaggacgaca acaggtggat ttttatcagt ctctacaact agatccgttt attttaaaac
     2281 aaaaaatacg agaagcagct tctaaaaaag aaaagtgcat gtatatttgt tcattgtttt
     2341 tacgatcatt attcatcgta ttgtttgcca tttgttttat cattataatt acaacattat
     2401 ttgaatcgaa gcataaacca tacgctgtgg ttttattctg tatgttgatg agtattcgtt
     2461 ttgttgactt tggttataag atttcccatt cgatcatagg tttagcaatc gtcatgttct
     2521 cactattagt agcaccgtat gtccagctga tcaaatggtc agttatgggc atgttgattc
     2581 attttatttt actaagcagc atattaatgg caaccgctag tgatcccaaa atggggaatg
     2641 cttctttgta cggcttttca tatctcttta ttgtttattc gttacctaaa gattcgttga
     2701 acaagaattt ctttacacaa acaagtagct tattattttt gtttttttgt tggttttcag
     2761 ttctccttta cagaaaacat cgagaaaaga acaaagacaa aagcttgttt aaagagattt
     2821 ttttgaaagg catgtattcg caggaaaaaa tttggatgct catctatgca tttggcatta
     2881 gtcttttgat cgttgcagga gagtatgtcc cttttcagcg attgatgtgg gcagggtttg
     2941 cattttcttc tattgtatct agctatggat tgatgtcgat tggtttcaaa gaacgagcag
     3001 tagaccgaat cattggctca ttgattggat gtgttttatt tattggtatc agccaattta
     3061 ttccttttaa ctgggtcggt atattaggtg gtctagcttt aggtgtttgt tctacctata
     3121 gatataaaac agtttttaat tcttttggtg ctttggcaat cactgccagt ttattcgggg
     3181 ttccaggagc agtaacgatc cgcatttttg agaatatcct tggggtatgt ttaggaatca
     3241 tgtatattgg ggtgactgaa atacttatcc gaaaaataag agaaaaacac ggtttgaatc
     3301 attagatgag atcgaataaa aaataaggaa aaagtgaaga tacacatgga tgataaattg
     3361 ctatcattcc atgtgtatct ttttacggta aatcagtgaa acgttcgact ttcattttta
     3421 atttatactt tttacggagt tcgtttattt gagccatcat ttcggatttg tgatgctttt
     3481 cgattgcttc ttcatctttc caacggtcga tcagtaaaag agattctgga tcttctagtg
     3541 gaaagtaata gtcatatttc tcgtttcctt cttctgcacg aatcgctttg acaatgtttc
     3601 tttcgaccat ttcttctgca aattttctgg cttgtccatt tgtacttgta tacaaaatat
     3661 tcactgtgat actcactaaa tcccctcctg aaaaaattct atcactagta tatcacggtg
     3721 ccagaaatta ttattcaaga tatgatacac attttttccg caatgctacg gaaatatata
     3781 ttttgaatag aaaacgctta caagatatgc ttggtttata aaaataaaag gagtgattga
     3841 tttatgaaaa aagcattgat tatttgtgcg gcaggaatgt catcctcgat gatggcctca
     3901 aagacaacgg atttctttaa gcaaaaaaga gaagaggtac tcgtagatgc agtttcagct
     3961 acagaaggcg ataatatgat taagaatagt gattttgatt tatttctgat cagcccgcaa
     4021 acgacgatgt ttttggataa attcaaaaaa ttaggagaat ctgttggaaa gcctgttgtt
     4081 agtatccctt tccaagcgta tgtcccaatc cctacaggca tccagaagtt agcagaggtg
     4141 atcgaagaga acatatgatg gaataggagt ggatgataat gaaacagaag gaaaaattgc
     4201 tgttgagata tttgattgat cacaagaagg agtatgtcac cagtcaacgt ttagcttctg
     4261 aattgttatt atctgatcgg acaatccgta attacttgca gcggatcaaa gagttagtag
     4321 aaaaaaacgg aggtaagatc attgctaaac caggttatgg ctaccaactg catattttac
     4381 aaagactgac atttgacttg tttttgagtc ggcaagaaat agtacctgga tatgctagag
     4441 aaccgcaagg attttatgag tccgaagatc gacaaaagta tatattgaac caattgcttt
     4501 tggaagatgc cattcttttt atggatgatt tggcagaaga gctttatatc agtcgttcca
     4561 gtttgacaaa ggacatgcaa gaaatcaagg agcgattgat tccatattca ctaaaaatcg
     4621 tttctaagca tggtcaaggg acatggatcg aaggggaaga aagaaatcga cggcatttta
     4681 tcatggatac tttttttgga aaccattatg gaaattcatt gaaagaatat ttagggcaaa
     4741 gccgtttttt cccagacatc agttttgaag agctagtcat tatcattctc gatgaaacaa
     4801 gagaagctaa gttaaaagtt tcggatttta tcatacagaa tctgacttta cacttggctt
     4861 tggggatcaa acggctccga gaagggtttg aaatcaagga attaggcatc gaacaagaag
     4921 tttctaagcg agtagagtat caagtggcgc agcggatcgt tcaacgtatt gaggtaatcg
     4981 caggtgtatc gtttcccgaa gaagaaattg cttatttgac attacatctc atggctaagt
     5041 cgaatcacaa agaaaatcaa aatgatcagg aactatcaaa ggaattagcg aaagttctga
     5101 aaagattgtc tcaggaattt catttttcat tagtagagga tctccagctt ttcaatggac
     5161 tactcgatca tttgtcaccg atgatgattc gattgagccg aggtattcgc attgagaacc
     5221 cattgactga ggagataaag aaagaaaatc ccaaagtctt tgacgcagta aaaaggcatt
     5281 tcagcaacat gccggctttg aaaaactata ccatcaatga agatgaatgg gcctatttgg
     5341 ctttgcatct catggcggca ttggaaaaag aaagagctgc gcataaacta catgcattga
     5401 ttatctgtgc aacgggttac ggcagtgccc aactattaaa gaatcgcgta gtcagtgaat
     5461 tcggtaaaaa tattacagtg gtaagtgtaa aaggctatta tgagatcaat gaaacaactt
     5521 taaaaggaat cgacctgatt atttcttcta ttgatctttc gacaatgttt ttcaaaattc
     5581 cagttttaca tgtcagtatt tttttgaatg aagatgatgt tcgtaaaata cgaaaggtag
     5641 ttggagaatc tataccctat cattcctcag atagaccgat accagcattt tctctacagc
     5701 aaaaaaagca gatttacacc gaacagttgt ctgaaaaatt tttcaagact tatacgtacg
     5761 aaccgaaaaa ggaagaaatt cttcatgatt tgctgcaaaa gctgagcata aatgaagaag
     5821 aaggatatat aagagaaatg cgaaagcaga tccagcaacg tgaaaatatg ggacaaatca
     5881 tattcagtga tacagtggca gtcccacatc ccgctgttcc agttggaatc gaaacaaagg
     5941 tagccgttgc attgattcct tctgggatgc agtgggatca atatcaagaa attcattttg
     6001 tttttttagt ttcgccttct tatgtcgaaa atgaaggaat tacggtcgtg actaaagcaa
     6061 tcgttaggtt agttgaccag ctaaaagtac agcaggaaat cttagctgaa cctatttttg
     6121 agaatttcag cagtaaattt atcaaactga tcgaataagg aggaaaacag atggctgaaa
     6181 aaataaacag tgaaacacta caagtgactt cttttgatat cattttccat agcggaaatg
     6241 cacggacact gatacatgaa gcatttcgct cgatgcgtaa agagatgttt gaagaagtag
     6301 aagagaagtt gcgacaagca aatgaagaga ttcttcatgc gcatcagtca caaactcaac
     6361 ttctgaaaga atatgccagc gggacaaaaa tagaaatgga aattatcatg gtccatgcac
     6421 aagatcatct gatgacgacg atgacattat tggaagttgc acaggaaatg aattatttgt
     6481 atcaaaaaaa taaatagaaa ggaaggatca ttgtgcagga tacagtaaaa aggaaaatcg
     6541 aattagaaaa aaagcaactt agtttgaaaa acatgtattt caatcgttat ctaatcgtac
     6601 gttacctgac tgcctttttc tttttcatga acatgcaatg gatgattctg cttctatcag
     6661 ctaaaagttt aggaagtagt ttaccgatga ttctgatttt agctattttg cctgcagtag
     6721 gagaacaagt aaagctttat cgaaaacacc aaacgaacgt tccatggaca aagtggtatt
     6781 ttttgttcca gagtgtcttt aatttattag tgattccagt gttgtttacc tcaggattta
     6841 cattcttgta tccttttatg gcaaataaca atggaggaca gttatttgtt ttcattcttg
     6901 ttgtaagcgg tatttttgcc agtgcattta tacagtatcg tttaaagaaa atttcactca
     6961 accaagacca acagtatatc cgtattaaac aatatgaaaa agcgttatat ttaggaaagg
     7021 agaataacta atgtttgatt ttttgcagaa atacctgatg ggacctatgg ggaaaattgc
     7081 gcaacttaaa atcgttcggg ctgtcatggc agcggggatg gcttctattc ctttcacgat
     7141 tgtaggctcg atgtttttgg ttttaaatat tttgccatta ccgttcccat ttttagaagg
     7201 attttttaat gcaacttttt tcaaagttag tgacttgtac atgatcgtca atacaatgac
     7261 gatggggatt ttatctattt actttgccat tgtgtttgct tatgaattaa cgtcaattga
     7321 acgagatgaa caaaaattaa atgttaatcc gctcacgggg gcattactat ctgtttttgc
     7381 attctttatg tgtatccctg aattgatcat gactgatggt aaaatcagct tgattgcttc
     7441 tatcaatgag acagaaactg tagtaaatgg tattaggatg ggctcttttg tcgaacgttt
     7501 aggaacttca ggaatcttta cagctattat tatgtcgatt attgcggtcg aattgtattg
     7561 tatgtgtgtc aagagaaatt gggtcataaa aatgccagat gttgttccgc caggagtttc
     7621 tcgttctttc actgctctga tcccaacatt tgtcattgcg tttgtggtga tgatcatcaa
     7681 tggattatta gttgcactag gaacggatat cttcaaaatg attgctatcc catttgggtt
     7741 tgttacgcag ttgacgaata catggcttgg tgtcatggtg atttatttct tgatccatgc
     7801 attgtggatc gtagggatcc atggagcgaa tatcatcact tctttcttga ccccgatcgt
     7861 attagctaat atggcagcta acgcacaagg cgcaaattat ccgttggcag gagaattcaa
     7921 caattcttat gtaaccgttg gtggatcagg tgcgacttta ggattgatca tctttattgc
     7981 attcctcgcg aaatctgatc agctgaaagt gttaggaaaa gcctcacttg taccaggatt
     8041 attcaatatc aatgaaccaa tcattttcgg gatgccaatc gtctacaatc cctatttagc
     8101 ggttccgttt ttcttagctc cgatggcttc tgctacactc gcttattttg ccattcggct
     8161 ggaaatcgtc aaaccgatgc ttgcacagat gccgtggcct tcaccagtcg ggatcggagc
     8221 atttgttggt agtggtggtg attggaaagc tgctgtgtta gcagtcattt gtgcaatcat
     8281 cgcattcatt atctggttcc catttatcaa attctatgat aataaattat taaatgaaga
     8341 aagagaaaag gcagcagaat tagctagtga aaagttaaaa tgatttctaa gaaaaaagga
     8401 actgtgacaa aaaatcacag tccctttttt tcttagaaat gggaaaccac tagtatataa
     8461 ataccattat tcttcaatca accgcttcac gattgcataa tccccttcat aaggttcatc
     8521 tacaccattg attttttgat agggatccac gccttttccc gcaataacga ctgaatcttg
     8581 cggagcgctt tctgctaaag cgcgtcgaat cgcttcagga cgatccattt cataatgaac
     8641 gatcaaatct ggattagtaa ttgcttcatt gatttcttcc gcgatttttt tcggatcttc
     8701 aaatgctggg tcatctgccg tcaaaaaggc gatgtcagct gtttctgata gcacttttcc
     8761 aaaatcatgt cgacgggaga ttgctttgtt tcctgggctg cctaatacaa caattacacg
     8821 gccatctgga tgttcatttt tggcaaattt cagcaatgtt ttcaagctta gataattatg
     8881 tgcatagtcc acatagacat gcgctccatt ggattggatc aattgatcca ttcggcctgg
     8941 tacacgagct tcttttaatc cgtcttgtgc atcttgactg gaggcacctg ttagtgctgc
     9001 ggcaatgatc gcactggctg cattttcttg gttgaatcct ccagccagca aaatatcata
     9061 agcagtatcg cagatagcta agcgatcttc atgagaagat aaagtaaaac cgtgagtacc
     9121 tttatctgaa cggatcactt gataattgct ttcttccgaa cgaccataag tgatcgttgg
     9181 aatctggaat agatcggctg tttccctaag taaatcaaaa tagtcacttt catgatttaa
     9241 aacaactgtt tttgaattca agatcaattg tcgcttgcaa tagaaatagt catcaaatgt
     9301 cggatgttcg atcggactga tatggtcagg cgagatattc aagaagattc cgacatctaa
     9361 agtcaagccg tatacgcgtt gtgttttgta agcttgtgaa gaaacttcca tcactagatg
     9421 agtcatacca ttttcaactg cttctgacat catacgatat aaatctaatg actcaggcgt
     9481 tgtcaaatgg gatttgaaat atgttttgcc atctaacgtt gtattcatag tagaaagcaa
     9541 tgctgttttt ttatttgttg tgtgatccaa gattgctttt gtaaagtacg cagcagttgt
     9601 tttacctttt gttccagtga atccgatcac tttcaattta ttttgcggat agtcgtaaaa
     9661 agccatagca agaagcgcca ttgctttacg gatatccgtt acgatgattc ctactgctga
     9721 attttcgtat ggttgttctg atacataata ttgaataccc tgttcgattg ctgaatccaa
     9781 atattcttct ttgaaattca ttcctttaca gaaaaacaaa gtagaagcat cagcttttct
     9841 tgaatcataa cttaactgaa gaaattcagc tttttctggt acatcaagat gccagcctct
     9901 tgttgaaaca aattctttta atagattttc ttttaatagt aaatgacgga tgtcttctaa
     9961 agagaagctc attgattgat ccctcgcttt attcaatttc ttggtttatt atagcacact
    10021 ctttttaata tatcgtttgt ttccgctatg acaaaatcca gctttattca aattttcttg
    10081 acacagggga caagcggatg agtattttca taaacaatga actgactgta atagatagga
    10141 gaacgaatag tgtctccaac aatccaaaaa cataataatt caaaaagacg ataagactat
    10201 tggtaagtaa aagtccttgc ggcattggaa gccgaaaaaa tttgtggaaa ataatcggcg
    10261 gtatcgttat accgccattt gaggccccga ctgtgtacaa tgtgtaaacc ccaagactga
    10321 acaaaagact tcctgaaatc agtgaaaaga aatgtgagga gatcatttcc acttttggaa
    10381 caatctctaa aacaacagga aaaagcagac ttcccgctac agtcttaaaa aatactgatt
    10441 ttcctaatag gacagcggct agaagcagca tcataagatt gatgctccaa acagtaactg
    10501 agcgttggat agaaaaggcc gtttcaacta aatgtccgat ggcgcccact ccggcggaag
    10561 ctatatcgtg agggagcaag aaccaattca atccaactgt gataaagaaa agacctaaaa
    10621 atataacggg tagttttttt atttcttgtg tcattgatat ctcctataaa tgttagccat
    10681 aaaaggctgt atatttcttt actttaccaa aaaaacgaaa ccgaattcaa aaaaacaatt
    10741 gttcttataa aagttatata aaatcgattg ccagtttctg ttttaccaat taaaatgata
    10801 gtaatgtttt gtagaaagtt ggaatctgac cgatggataa tcaaagaaaa ccagcattag
    10861 atcaattaac accgcaagaa aaaatggcac gaggctctgc ttggatgacc gccagtaata
    10921 tcatttcaag attgctaggc gctgtctata tcattccctg gtatgcttgg atgggcgaaa
    10981 atgctaaggc tgccaatgga ttattcaata tgggatacaa tatatatgca ttgtttctac
    11041 tgatctctac agcaggaata cctgctgcga ttgcaaaaca aactgcacgc tataattcat
    11101 tgaatgaata tggcacttca cgacgattat ttatccgtgc attacagatg atgggcgggt
    11161 taggcctgtt gtttgctttg ttcatgtaca tcgcctctcc ttggctagct catgcttctg
    11221 gtggcggaga agaactgatt ccaacgatgc gttctttgag tatcgctgta ttggtttttc
    11281 cttgtatgag tgtgatacga gggtattttc aaggcaatca agaaatgatg ccttatgcgc
    11341 tgtcgcagat tgtagaacag gtggcacgta ttttttatat gctattggct acattcatca
    11401 tcatgaaagt catggatggt gactatgtga cggcggtcac gcaatcaact ttcgcggcat
    11461 ttatcggtat gctagcaagt attcttgtcc ttttgtattt tttgaagaaa catcaagcgt
    11521 atacatcggc gtttattcac tacagcgaaa acaaaataaa tattgcaacg aaggaattgt
    11581 tgttagatac cgttaaagaa gcgattccgt ttattattgt gggttcaggg gtaacgatct
    11641 tcaaattagt cgatcagttc acttttatga agatcatgtc tgcatccacc gagtattcca
    11701 atgcacagtt actggatctt ttttcgattt ttagtgccaa tccagataag ttgacgatgg
    11761 tagttattgc attggcaaca tcgatcgcgt ctactgggtt accgttgatt acagaagctg
    11821 ttacgttgaa agatcgagta ggtctggcaa aattgacaag cggaaattta cagttgtttt
    11881 cattttttat gtttccggcg acatttggtg ttatgttact tgcctatccg ctaaatacat
    11941 tattttatac accggattct ctaggaagta atgtactgat ccaagcaagt tttgtaggac
    12001 tcttcctagg actatatatg ctagtttcca acatgctgca aggaatgttt gaaaacaagg
    12061 cggcaattaa ttatttggtt attgggtttc tagtgaaact ccttcttcaa tacccagcca
    12121 ttcgtttatt tgaagtatac ggccctttat tggcgacaat gatcggattt gctgtgtctt
    12181 gtaccttgat cttaaagaga atccatgaag tagcccgctt taaaccaagt tttgtctggc
    12241 gcaggacatt gctgatcttt attcttacct tgattatgct tttggcttcg tggatcacaa
    12301 agatgatttt tggtgctttt ttaaacgaag atagcaaatt ccagtctcta ttgttgattc
    12361 ttgtagtagc aggtataggg gctttagtgt atggttattt agctttgaaa atccgcttgg
    12421 cagaaagact actaggacca ggaatagcgc gtttacgaca taaattaaaa ataaaataag
    12481 tgaatcagaa gagctagatt gatgctcttt tgaaatgggg gaaacgcatg cgtttagata
    12541 agtttttagc agatatggga cttggcagcc gcaaagaagt caaaggatta atcaaaaaag
    12601 gaacgatcga agtcaatgga caagtggtga aaagcgataa agcgcaagta aatgaattcg
    12661 aagatgcggt tacttattta ggagaaatca ttacgtatca aaaagatttt tactacattt
    12721 tgcataaacc tgcaggagtc atttctgcta ctcaggataa tcatgatcaa accgtaatcg
    12781 atttattgga agaccaggat tatcgggaag atctttttcc agtcggccga ttagataaag
    12841 acacagaggg cctcttgatt ttaacgaatg acggggtgtt tgcccatcag ttactatcac
    12901 ctaaaaaaca tgtggagaaa gaatatctag ctgaggttag cggtataatg acagaagaag
    12961 atatccgttt atttgcagaa ggactgatta ttgatggcga tgagcagaca ttgccggcaa
    13021 aactccaaat tgatcaagta gatcaagaga cagaaacttc aattatccgt ctgattttgc
    13081 atgaaggaaa gtttcaccaa gttaagcgaa tggtcaaagc agtaggaaaa gaagtcttat
    13141 atttaaaaag aatccgtatg ggaaaatttt ggctgcctaa agatttgaat aaagggcaat
    13201 atcgacccat gaccaaagaa gagctagaac aagtgagaga aaaataattg aatggatagc
    13261 taaaagaata agcagagtag ttgtagcgcc atctgaaaag cagacttgtc cgtctgactt
    13321 tcggatggct tttttgtgaa atttcggctt atttccgtag aagctacttc tggaacaccg
    13381 tttgttcgga ataagggact gtgacaagac ttttgttaca gtccccattg ttccttgtga
    13441 ctcagagtta gatagtaagg acacgatctc cctaatactc aggccaaaac gctgaattca
    13501 caacctctga taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa
    13561 aatatgagga actattttcc cgtttttttc tctaatactc aggccaaaac gctgatttca
    13621 caacctctga taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa
    13681 aatatgagga actattttcc cgtttttttc tctaatactc aggccaaaac gctgatttca
    13741 caacctctcc tatactttgt ttcattttcc ctatactttg tttatttatt ctcattattg
    13801 aaagcgctat aattacgttg cgaatgaatc gaaaggggtt tttagatgaa aaaacgaaag
    13861 gggttcaatc atttttttat gaatctatgg cgttataaag cacttgtcct gatggctgta
    13921 ccgggtatgc tttggatgat ttttttcttt tacatacctg taatggcgaa tgtcgtagca
    13981 ttcaaaaatt ttcatatttc agcagatggg ttcttggcta gcttgaggga aagtccttgg
    14041 gtgggttggg aaaatttcaa atttttattt tcttcggatc aagcatttct catcactaaa
    14101 aatacaattt tatataatgt agcatttatc cttttgaatc tgctgatctc agtcgtattt
    14161 gcaatcatta tgagcgagtt gagaaataaa cgactcgtta aagtttatca aacgatgtcc
    14221 ttactacctt attttctatc ttgggtcatt atcagttact ttgtttacgc ttttttaagt
    14281 cctgacaaag gaatattcaa tcagtggatc actggacatg gaggagaagc tgtcaattgg
    14341 tataatgaac cgaaatattg gccgtttatc ttggtgttca ttggtacatg gaaagggatt
    14401 ggttataaca gcattattta ctttgcatct gttatgggaa tcgatccgac ttattatgaa
    14461 gctgctatgg ttgatggagc tagcaaatgg cagcagatca aacatgtgac gataccacaa
    14521 cttattccac taatgacgat tttaacgatt ttagccgtag gaaacatttt ccgagctgat
    14581 tttggcctgt tttataacat tcctaggaat tccggtgcat tatatgatgt gactcaagtt
    14641 ttggatacgt atatctacaa tggcctgaca tccacaggag attttggtat gacggctgct
    14701 gcaggacttt accaatcagt tgtcggcttt gtcttgttga tgatcacaaa tacgatcgcc
    14761 cgacgttttg atagcgattc tgcattattc taaggaggaa aaaaatgaaa aaaaagaaag
    14821 tggagagagt ccaagtccgc tctttcaata agacggctaa ttttttctct aatataatga
    14881 ttgcactctt tgctatttcc tgtattttgc catttatatt tgttatcgcc atctctttta
    14941 ccgatgagtc catattgtcg actcacgggt acagtttttg gccagaaaag ttcagtatat
    15001 ttggttatac gtacttgttc gaccagatgc aggataaaat tttccaagcg cttttcgtca
    15061 ctgtacttgt tactgtttta ggtacactga tcaatagcac ggctacttct ttatatgctt
    15121 atgcgatttc acggtcaaac tttccattcc gtcgtttttt taccgttttt tgtttgatta
    15181 cgatgttgtt ctcaccaggg atggtggcca attatcttgt tatgacaaat cttcttcagt
    15241 taaaagatac gatttgggca ttgatcttgc caatggctgt cagtcccttc aatattattg
    15301 tgatgcgcac attctttaaa cgttcggtct ctgattcgat tattgaatcg gcacggatcg
    15361 atggagctag cgaactgcga atatttgttc agatcgtttt accgttagct gttccaggta
    15421 ttgcgacaat cagtttattt gccgcattgg gttactggaa tgactggttc aatgctttac
    15481 tatacatcca agatgataag ctagttccac tacagtatct tttgatgaaa atccaaagta
    15541 atattcaata tctgacacaa aattcaggag caggaagcca attgacaggc ggattagcct
    15601 cagttccagg agaatctgcc agaatggcga tcgtagtcat ctcgacgttg cctattgcga
    15661 tcagctatcc atttttccag aagcattttg tcaaaggtct aacaatcggc ggagtaaaag
    15721 aataaagaaa caaaaatata aatcataaaa ttaggaggaa gaaaaatgaa gttatggaag
    15781 aaactagcct ttacaggtgt ttcagcgttg ttgttgggaa cattagcagc atgcggaggt
    15841 tctggttcta aagaccaggc agaagctagc aattcggaca ctttgcagat gtatcaaatc
    15901 ggagataaac cagataattt cgatcaattg atggaagtag caaacaaacg aatcgaaaaa
    15961 gagatcggtg taaaagtcaa tatcaattac attggctggg gcgattacga aaagaaaatg
    16021 aacgtcatca tttcttccgg ggaaaattat gatatcgcct ttgcgaacaa ctatgtttcc
    16081 aatgcccaaa aaggagcctt tgctgatttg actgaattag cgcctaagta cgctgaaaaa
    16141 gcttataatg atttagatga agcatatatt aaaggaaatc tggtcaatgg aaaattatat
    16201 gctttcccag tcaatggaaa tgtctttgct caacaagtac ttacttttaa caaagcttta
    16261 ctagataaat acgatctttc aattgatgga atccaatctt acgctgatgc agaaaaagtc
    16321 ttgaaggaat tccatgaaaa agaaccaaac acggcagctt ttgccattgg acaaggcttc
    16381 aaagtccaag ggaactttga ttatccttta gggaatacgt taccatttgc tattgatctg
    16441 gatggagatg attcgaaaat catcaaccaa tacgataatg aaacgtatat cggactgtta
    16501 cgtacaatgc atagctggta caaacaagga ctcattccaa gtgacgctgc aacgagcaat
    16561 aaggattatc cactagaagg aaatacttgg ctaatgcgtg gagaaacaca aggaccgtat
    16621 gattatggcg atacaatttt gacaaatgca gcaaaacaag aacttgtctc aaaagcaatt
    16681 actgttccac taaaatctac agctcaagca caaatggcaa attttgtcgt atcaaatact
    16741 tcaaaaaata aagaaaaatc agtagaactt ctagggctgc ttaacagtga tccagaatta
    16801 ttgaatgggc ttgtttgggg gatcgaggga gaagcatggg aaaaagtcga tggttcagat
    16861 gataaaatca aattgctaga tggttatcag ccaaatacac atatgtctgc ttggaataca
    16921 ggaaacaaca agattctata tacacaagag tctattacgg atgacatgat tgccaaacgt
    16981 gatcaatcga ttgctgatgc agaaacttca ccgattttag gattcagctt caacactgac
    17041 agtgtcaaaa cagaattaag taatatttct aatgtcatga atcaatattt agatggattg
    17101 aatacaggga ctgttgatcc agatgaaaca ttaccgaaat tgaaagacgc tttggacaag
    17161 gctggctatg ataaggtatt gaaagaaatg caaaaacaat atgatgagtt ccgacaagaa
    17221 taataatgaa taaagacaaa ggggttgtga caaaagacgt gtcacaacct cttgttccga
    17281 ataaacggtg ttcaaaagcc agtttctcgg tattaagcta aatatatgta aaaatgtgga
    17341 aagccatatt cacaaaattt ttcttactac tcgaaactaa gcggctattt cacaaactct
    17401 tggtaaacgg tgttcaatca gctaaccctc ggtattcgct cacaaaacga caaaatatga
    17461 ggaactattt ttccgtttgt ttctctaata atcaggtcaa ggtgctgatt gcccaacctt
    17521 tttttgtata atgagaaagt ataaacttaa tgtttggagg agaagatatg ttagggaagg
    17581 ttttggaaga gttatttatc cggatctggg tcattataaa actaaccttg tatttctgga
    17641 tatatacatt tgccggcggg atcatctttg gattaggtgc ggcatggaaa acagtcaatg
    17701 aactatttta tttgtacgga ttcgagtata aagaaatcac aataaaaaga ggctggaata
    17761 tatataaaag aaatttttta agaggcaatc tgctatttag tttattttta tctggtactg
    17821 ctttattgag ttacaattta tatttatctg ttcaaatcaa agggctcatt tttttagcta
    17881 ttgattttat tttacttttt gccttgctct gcctatttgc tacttatcaa tacagtatga
    17941 ttttagatag tgaatatacg atctctgttc ctaatctgct aaagctaagt tttatttcgg
    18001 ttttttccag cttttcgtct tttctaaaaa taattattgg tagcggtata attttaggcg
    18061 tgacttggca attcaaagga ttgatcctgt ttggtgtcat tggtcttttg acggtttgga
    18121 atggtacgat gacaacacat tggcgtgaag aattagataa acagttggaa agttatgaat
    18181 aagtttcgga ttctattttc aaaaggaacc ttactaaatc gtctgttgcg gaaatacgcg
    18241 gttatcatga tcggtgtaac gatgactgct accgttattt ttagtatcca tacttgggaa
    18301 caaaatcaaa aacaggcaga aaacatgaca agtgatgccg ttcaaagcac aagcagaatg
    18361 ctgaatgata aaacaacctt gagtaggatc atcaaaaacc agcttgtagg gaattccgaa
    18421 aagatcgaaa atgtgacgac ctacttaaca aaacccatag atcagtatct gatgtatgta
    18481 tacgaacagc aaaacagtac cgatgaatta gtttctttcc caaatcaaat caaagatctc
    18541 tacgcaaatt atgaagaact aagtgcgata tatatcgtgt tgaatcaact accggagtat
    18601 tatgaatctt ctagagaaaa caaaggtggg gaaataaaaa aggggacacc aaaattacta
    18661 gacgcctttt atatcaagtt gcctatcaca caaggaggag ctgagtcagg aagtattttt
    18721 attggttttc aaaagaaaga actagatatg attttagaaa atctaacgtc attcaatgga
    18781 ctctctttat acatgatttc tggaacgaca aatcgactat acacattcca tgataataaa
    18841 atagctaaag aaacgtttga aagacaagaa atgatcatca cagagagtct gaagaaaaat
    18901 tcacaattgc cgattgacga tctggaaaaa aacaattttg ttcaacacca agaactgtct
    18961 gatgattatc gtatattagc tgtactagat aaaaaaagtg taaaaatcga aacgggaaaa
    19021 aatcttgccc cgctgatcat tggtatcatt attttagaca atatactgct tatctttctt
    19081 tataaaacat tcaaacgata ttcacagcaa gtatctatcg tcatgcaggc catggatcaa
    19141 acagcagcag ggaatttaga gacgcggatc gacataacaa acacggaata tgaactgaag
    19201 gaactttcaa tcggtatcaa cgaaatgttg gatagcatca atcagtttgt agaagacatc
    19261 tacaaattag aaatcaaaca gcaagacgca catatgcggg cgcttcaagc acagatcaat
    19321 ccacactttt tatataatac attagaatat atccgaatgt atgcaatcag cgaaggaagt
    19381 gaagaattag cagatgttgt gtatgcgttt tccgctttgc ttcgaaacaa tacgaatcaa
    19441 gagaaaacga tcactttaaa agaagaactg gacttttgcg aaaaatatgt ctatttgtat
    19501 caaatgcgtt atcctaatcg agtagcctat cattttatga tcgatcctga tttggaaaag
    19561 atcgaagtac ctaaatttgt gatccagcca ttagttgaaa attattttaa acacggtatt
    19621 gattttactc gattcgataa tgcgctaagt gtcaaagtct tgcaggaagg caaacgggta
    19681 aggatcatca tcaaagataa tggaaaaggg atgactgaaa aacggctaaa acagattgaa
    19741 gaaaaactgt ctcatcctaa agtggaactt cacggttcta tcggtctgca aaacgtgaat
    19801 gaacgtttac gtgccagctt cggcagcagt tattatatgt cgcttgagaa taatgagaca
    19861 ggtggactga ccgtttctat tacattcaag gagggatgag cgtgtatcaa gtgttattgg
    19921 tagatgatga atacatgatt ttgaatgggt taaaaaagat aattgattgg caaagtttag
    19981 gctttcaaat agtagcaaca gcagagaatg ccaaagaagg actagctgta cttgaacagc
    20041 gacagattga tttagtagta acggatgtga caatgccaga aataaatgga ctggaattta
    20101 ttgaagcggc tcaaaaagaa cgtcataatt ttgaatttat gattttatca ggataccaag
    20161 aattcgatta tttgaaagga ggtatgcaat taggcgccgt gaattatttg atgaaacccg
    20221 tgaataagtt cgaattggtt gaaagcctca agaaaatcaa aacacggtta gatcagcaaa
    20281 atgaacaaaa aaatcaacaa gaaatctatc aagaactgtt attcagtcaa tggttgaatg
    20341 aagaattgga tgaaataagt gaagaagaaa taataggaca aataagtgag aagcagcata
    20401 ggatagtatt gattcaactg gcaagaactc atgatactct tatcaataga tggttgcaag
    20461 aacggcaaca aatcttttac tatcaacgaa attacggaga ccgtgtattg atcacgttgt
    20521 tgttggaggc agatgaagtt gatggcttct gttgttttgt tcaagaaaac tttcctgatc
    20581 aggaatggct gatcagtatc ggggaagaga cagattcttt ggacaaaatc cctgaaacat
    20641 tccaacaagc gaaagacaat ctacagttgc atcaatttta tggagataaa gacgagcatg
    20701 ttttttacgc agtacaagca gaaacaaaag atcaaaccat cgatttttca agtttcagac
    20761 gcgtgctgca aaataaacaa ttggaagtcg ctcaaaaaat gatcactgat ttttttgaac
    20821 agtttcagtt agcagccatg atgccggaag atatacgata ttccagtttt ttactgttta
    20881 tggagattca acgggaattg attgatctgg aagatgagga atatttacaa ggaatcgaaa
    20941 aaatccatca ggcaaaaacg gtgcaagaac ttcagcagct acttctgtca ttcatcaaaa
    21001 agcatcagag acagaaaaag tacagtgaca atgtggaaaa agtaatcgta atcctgcacc
    21061 agcattatca agaaccactt acactcaaag aagtgtcaga aaacctgcat ttaaatgtca
    21121 tgtatctagg acagctgttc aaaaaagaaa cgaaaaaaag tttttcagct tatttgaacc
    21181 atttacgtat ggaaaaagcg aaacaactgc ttttgcacag taatcaaaac atcaatgaga
    21241 tagcaagtga gattggctac aacaacacca cgtatttctc taaattattc aagaaaatcg
    21301 tcggcagatc ccctaaagag taccgagaaa acagtggaga atcataaaag aaaaagccaa
    21361 tgtaatgaaa taacttataa aaaattgtct agaaatctaa ttttgggctg ttcttattac
    21421 ttgaggcaag gcagcttttt catgacctct cgataaacgg agttcaaaag ccagtttctc
    21481 ggtattaagc caaatttatg caaaaatgtg gaaagccatt ttcacaaaat ttttcttaat
    21541 actcgaaact aaacagcttt ttcacgacct ctccactaaa cggtgttcaa tcagctgacc
    21601 ctcggtatta gctcaaaaaa tggcaaaata tgaggaacta ttttgccatt tgtctctcta
    21661 atactcaggt cagaacgctg atttcacaac ctctcaataa acggtgttca aaagcttgca
    21721 tctgcggtaa taagaccaac caaacgaaaa atatgaggat ctatttttgc ttggctgttc
    21781 ttattacttg atgcaggaca gctttttcac aacctcttgt taattatagt ttgataagga
    21841 aaaaggcaaa tcttttgctt gatatttctt agggtgaggg atgatcccta attggtaaga
    21901 gatcgtgccg cctttcagca aatcttgatg ggtaaaatat aatttcgtat attctttgtc
    21961 catccgtttg attttatgga taaattgttg ctgcggccga ttaggcgttg cttcaatcgt
    22021 caattccttt ccatttgaca aaagcaaaac agccttgtca attaatggca taccgataac
    22081 atattcaccg gttccaggcg tgacaggata aaatcccaga ctattgaaga tataccaagc
    22141 ggccatactt ccattgtcct catctccagg gtaacccatt ggagaatcgt cgaaggtctg
    22201 agtcatcaac tgtttaagca gtggctgtgc catttcaggt tgtcctatat aactgaacaa
    22261 gtaaggatag tgaaaacttg gctggtttga aatagctaat tgtccaaatt ctatcgcggc
    22321 catctcactc atttcgtgga tctcaaaacc atatcctcct gggtcaaacg ttgggggctg
    22381 attgcacagc tcaatgagtt tttctttata tctctcactg ccaccatatt ttccgatcag
    22441 tcctgaaaaa tcgtgataaa cagcaaagct gctttgccaa gcacttcctt ctgcataatc
    22501 ttgtccccaa cgattagctg aaaatggttc tctgaacttg ccatctttat cttttgaacg
    22561 cataaatcct gactcatagt caaagatatt ttgatagttc aatgattgct gctgatattt
    22621 cttcgtcatt tcctcttctt ctagtacctt ggcaacttgg ctaatacaaa aatcgctata
    22681 agcatagtct aatgtgtgat tgactgattc gtggtagtga ttaggaacat agccatatgt
    22741 caagtaatct tctgttcctt ggcgtccata atttggatgt ttgctttgaa ccgtagcacc
    22801 tttttccatt gccgttagaa attcaggcat caagtctcgt cggatatctt ttacagcagc
    22861 atctgcaatg accgcatcga tcaatgtccc aggcataagt ccacgttcat caggagacag
    22921 ccattttggc aaatagccac tttctctata gctgttcaaa aaaccttcca gcatttcttc
    22981 gtatttttct acagcaatca aagaataaag aggataaacc gttttatacg tatcccaaaa
    23041 cccattattt gtatagagaa caccaggttt tatagatcga ctagtcgtat catagtggat
    23101 tttttgccca ctaggatcaa tttcataaaa tgtttgtgga aataaaaaca cccgatataa
    23161 attatgataa aacgtccgca attgttgttg atcatggtgt gtgagctgta tacgatcaaa
    23221 ataggactgc cattgttctt gactgtgagc aaggtaagtc tctttgcttt ggttttgttc
    23281 tagttccagg ttataagctg cttgttccga gctgataaaa gatgtcccaa atcggatagt
    23341 ttgttttttt gtctgttcaa aatacaacgg gatcgagtcg ctatttttgt tggaaacagc
    23401 taactcatca attgttaaag gatattcaaa tctcaatata aaataaaaag aaaaatcagg
    23461 atcttctgaa ccagcaaaat gtgtgatttt tccttccact gtgtaaggat ctataacaaa
    23521 gagctgatgg cgtcccggaa aggataaaag taaaccgctg tcatttttgc tgtaatcaat
    23581 agataagatt ccgccataca tgctaggtat caatgtagaa cagatgccat aacgtaattg
    23641 acagatcgac agatgagtcg ggcaaaatat actttcttct gggcggtaag aactttgagc
    23701 atggaaaagg gtgttctcct gtagttttcc attgatcggc gtaaacagca tatgactgaa
    23761 atcacccatc caaggacttg gttgatgggt aagacggtag ccttgaaaaa cgcggtcatc
    23821 aggatgaaac caccagctgc cgttttgatc cgtagtttgc ggtgcaaaat aattcatccc
    23881 aaaaggaacg ccagtataag gctggcagtt cccattagag aaatttggct gattcgctgt
    23941 tgcatgtcta gtatctattt gaccgatatt cattttattt ctcctttgtt gattgtcttt
    24001 tgatgaatga aactggaaat ttactatcgg atggtcgatc ttttgtctct aaccaagtga
    24061 ccaaagcatc tcccgcaagc ttacctaact gttcaaaatc ttgtgcgatg gttgtcagtg
    24121 gcgggtcaac aagagctgct gcttggatat catcaaatcc gataattgaa aaatcttcag
    24181 ggatatgata accatgctgt ctcaagagat tcatggtctg gatagcgaca acatcgtttt
    24241 cacaaacaaa agcagttact tcatacttag tgatataaga aagcaattca tctaatgtcg
    24301 cgcttttgtc atccagtgaa gtgtggaaag tcaaaccagc tttgtccaat gcttcaaggt
    24361 aaccaaggta acgctgtcga acggattgtg gatgagtctg cgtaccaaac aaataagcga
    24421 tttttgaatg tccctgttcg atcaaataag aggcagcaag cgcaccgcct tggaaattat
    24481 cggaaagaac ggtaggaaaa ggtaactcat agattttttt atctaatatg acgacaggga
    24541 attctttcaa tgaaagctca aaaagtaagt caagatgttg ttctgtatca agagcataat
    24601 aaatcaatcc gtcaaattca ttgattagct cttttgctgt tttattttgt agaaagtcaa
    24661 gcgtcgtcat catgacatca atctgtttat cttgcatcac agggttcaat cccttgctaa
    24721 aatcaccaac agacaaatca gcgacatatg gaagaagaaa cagaatccgt cgtgtttttg
    24781 taggagaagc aagaatctgt tccggagaag cggatttaac gaaactgcct ttcccgcgaa
    24841 cgcgataaat aagtcctaat tgctctaatt cagtcaatgc acgtttggaa gtgattctgc
    24901 ttactttata ggtacgtgaa agttcttttt cagttggtag ttggctgtct acaggtaatt
    24961 caccagttaa aatagccgtt tgcaaatcat taaatattgt ctggtacaat ggttgattca
    25021 tataaacacc tcttaatgat atatcatatt caaataatac cataatggat gaaaaagtaa
    25081 ataaaaagat attttttgaa agcgtagaca taattggctg tatgaagtat aatctttaaa
    25141 gatatatcaa atagaaagaa ggttttatta gtggcttata aagatatacc aaaatcggtg
    25201 cagaaattta tggaagatat cacacaaaaa tgtggggata tccatgcgga ctgggcaaag
    25261 aattttacag cagcatttgc caatactctg ttgacaacag tcaaaaagca aaatgacgga
    25321 accacctttt tattgacggg agacattcca gcgatgtggt taagagactc tactgcacaa
    25381 gttcgtcctt atttagtgat tgcaaaagaa gatgaggaat tagctgacat gatcagcggg
    25441 ttagtcaaaa agcaattttt ttatatcaat atcgatccat atgcgaatgc cttcaacgaa
    25501 gaagctaacg gtgctggcca ccaaacagat catacaaaaa tgaacgattg gatctgggaa
    25561 agaaaatatg aaattgattc tttatgctac ccaatacagt tggcctatct tctttacaaa
    25621 aatacaggaa aaactgatca attcaatcaa tcttttattg aaggtatcaa aaaaatcttg
    25681 gacgtgttca aaacagagca agatcatgaa cactctcctt atacatttgt acgagacacg
    25741 acaagaaaag aagatacgct gatcaatgac gggcgaggtg caaaaacagc ttttacagga
    25801 atgacatggt ctggtttccg tcctagcgat gatacttgcc gttatggata tctggtacca
    25861 tccaatatgt ttgcggtggt cgtgttaggt tatgtggaag aaatttttca aacgatactc
    25921 gatgataaag aaattgtaca gcaaacacag aaattgaaga aagagatcca agaggggatt
    25981 cagaatcacg gacgaacggt taatcaaaaa gggcaaacga tttatgcata tgaagtagat
    26041 ggaatgggaa acgccacagt catggatgac agtaatgtgc ccaatctgat cgccgcacct
    26101 tacttgggat attgttctga acaagaggaa gattatctgc aaacaagaag aacattgttg
    26161 agtaaagaaa atccatattt ctatgaagga aagtacgcaa aaggaattgg atcctcccat
    26221 acgccagaaa aatacgtttg gccgattgca ttagctatgg aaggaatgac aacgtcagac
    26281 aaatctgaaa aagagcggat attgaattta cttgtagcaa ctgacgcagg aacacacctt
    26341 atgcacgaag gattcgatgt gaacaatcct gaaaattata cgagagaatg gttttcttgg
    26401 gcaaatatga tgttttgcga attagtcatg gattactttg atattagagt agaatagtag
    26461 gaggtatcgt aaatgaaaaa gaaagtatat atcatttctc atagccactg ggatcgtgaa
    26521 tggtacatgg cttacgaaca gcatcacatg cgactgattg aattgataga cgatctacta
    26581 gagctatttg aagttgatcc gtccttcaac agttttcatt tggatgggca aacgattatt
    26641 ttagatgact atcttcaagt aaggccagaa aaaagacagg caatccaaca agcaatcaat
    26701 gaaggaaaat tgagaattgg accattttat atcttgcaag atgattttct tatcagctcg
    26761 gaatcgaacg tgagaaatat gctgattggc atggaagaaa gccgtaaatg gggaacccct
    26821 gtcatgttag gctattttcc cgatacattt ggaaatatgg gacagacgcc tcaattaatg
    26881 aaacaagctg gtatttcagc agcagcgttt ggccgtggtg taaaaccaat tggctttgat
    26941 aatcaagttt tggaagcaga aaactattct tcccaatact cagagatgtg gtggaaagga
    27001 cctgatcaaa cagcaatctt tggtctgcta tttgccaatt ggtatagcaa cgggaatgag
    27061 attccagtag aaaaagaagc agctcttgcc ttttggaagc aaaaattagc ggatgcagaa
    27121 caatatgcct ctacgaacca cttattgatg atgaatggtg ttgatcatca accggtacaa
    27181 aaagatatat caaaagcaat ccatctcgca aatgaactgt ttccagatta cgagtttatt
    27241 cattctaatt ttactgacta tctggaagca gttcaaaaag atgtgccaga agacttaggc
    27301 tcagtagaag gagaattgac aagtcaagaa acggatggct ggtatacttt agccaataca
    27361 gcatctgctc gggtttactt aaaacaatgg aataccaagg tccagcgaca gctagaaaat
    27421 attacagaac cacttgcgac gatggcttat gaagttagtg gaaactatcc ccatgatcaa
    27481 ttagattatg cttggaagac attaatgcaa aatcatcctc acgacagtat ttgcggttgt
    27541 tcagtcgatt ctgtccatcg ggaaatgata cctcgttttg aaaaagcaga tgaagttgga
    27601 aagtatcttg cacaagattc cttagaacag ctgaccgcag caatcgatac gaccggattc
    27661 ccaaaagaca gctttccatt tgtcattgta aatactgcag gaatggataa aactggtgaa
    27721 gcagaaataa ccatcgaatt agaaagaaaa agattcgctg aaggaatacc tgaacaacta
    27781 tatcaagagt tagaaaattt gcctaaacgt aagtatcatg tagaaacaaa aagtggggcc
    27841 actataccag ctattttatc tgaagaaact gtccaatttg gttatgattt gccgaaagac
    27901 cgtttccgtg tgccatatat ggcaagaatg atcaaagtga ctttaccatt agaaaacatg
    27961 ccagcatttt cttgggaaac attcgcgctt gtagaagggg aagcgaaagc agaagaaaag
    28021 gaaacaatga ttcatcagag tggacgaatc atcgaaaacg gccctctaca tttgacgatt
    28081 gaaaaaaatg gtaccattac aatggaagat cgcaaaaaca aacgaaagtt gaataatctg
    28141 catatttttg aagatatcgg cgatatagga aatgagtata tctttaaaca acctttctgt
    28201 gatcagccaa tcctatccag taacaaagaa aactctgaag taaaagtatt agtagataca
    28261 ccggaaatag caaaaataag tattctacag gaaatggaaa tccctgtttc tgcagacgag
    28321 cgtttagaaa aagaacagca gatggttgtg gaatttcgtt atcgaaaagc agaacgatcc
    28381 aaagaaaaac gaatccttca aataaaaaca atcatgacaa tcagaaaaga tagtaaaaaa
    28441 atcgactttg aaacgactct cgacaatcag atgaaagatc atcgcttacg tgtcttgttt
    28501 cctacaaagt tacatgtgga acatcacgaa gcagatagta tttttgaagt ggtgaagcgc
    28561 ccaaaccatg tgtctaaaag ttgggaaaac cccacgaatc cgcaacatca gcaagcattt
    28621 gtcaatattc atgatgaaga gtacggtgta acagtcggaa actttggttt gaatgaatat
    28681 gaagtaacag aagacggaca aatcgcagtg acgctacttc gcagtgtggg agaactaggc
    28741 gattggggat attttccaac accagaagca cagtgtctag gtgagcatcg gttcaattac
    28801 agcattgaac tacatggacc agaagaaaaa ttctctactt atttgcatgc atacgcagca
    28861 cagattcctt tttccactca acaaatcaaa catcatgaag gaacattgat ttcaaaacaa
    28921 caatatttaa cgataaaaag tgaaacgttt gcaattacag ctttgaaacg cagcaagttt
    28981 agtgataaag tagtagtaag aggtttcaat atgtctagtc atttagaaaa attggaaata
    29041 actaaagaca atggaaaaac tgtcatattg aatctgcttg aagaaccaac gaagcaagcg
    29101 gttgtcccaa taatccaacc ttatgagatt cggacaatcg gattcgagga ggaaaacgaa
    29161 tgtatggcgg aatagaagca ggcggaacaa aatttgtgtg tgcggtttca gatggtggag
    29221 aaattttaga aaaattaagt atccctacca caacaccaga agaaacattg gatcaggtat
    29281 ttgaattttt tgatcgttat gaattgaagg gaatcgggat tggctcattc ggcccgattg
    29341 gtatcgacaa aacaaaagat aattacggat acgttttggc aactcccaaa aaagggtggg
    29401 cacaattcga ttttcttggc acaatcaagg aacgctacaa tattcctgct gcttggacaa
    29461 cggatgtcaa tgctgctgca tatggggaat tgaagcaagg agcagcacaa ggaaaaaata
    29521 gttgtattta ccttaccgtg ggaacaggaa tcggtgcagg tgtcgtgatc aatgaagaaa
    29581 ttttttcagg gatcgcacat cctgaaatgg gacatatttg ggtgaaacgc catccagatg
    29641 accattatga aggtacttgt ccttatcata aagattgttt agaaggatta gcagcaggac
    29701 cgtctattga ggcacgcaca gggatcaaag ggcaagatct gccgcaagat catcctgttt
    29761 gggctattca ggcttattat attgctcaag cactgatcaa ctatacgttg acgttagcac
    29821 ctgaaaagat tattttaggc ggtggggtaa tgaatcagga tcatctcctt caaaaaatcc
    29881 gtcagcaatt tgttgaattg atgggtggtt atatggaaac acctcaagta agtgaatata
    29941 tcgttcgttg gggactgccg aatgaaagtg ggattatcgg tagtttgctg ttagcagaac
    30001 acgaacatca aaagtaagca gacaaattac acaaaaagaa cagagtctta tcattatctg
    30061 ctgataagac tctgttcttt tttatttcta ttcccataat ccaggtaaag ctttaccgac
    30121 tattttttct tgagtaaatg gatggatcat gtgcagttct aatgcatgga gcatcagtcg
    30181 ttcagctgtt ctattttggt agagagggtc tccaacgatc ggatgtccct tatgagctaa
    30241 atgaactctg atctggtgtg tacgtccggt ttccaaaaca caatagactt gtgtttgttc
    30301 agaaagtact ttgttgacag tgacatgtgt caaggcgctc tgaccatttt tatcatctac
    30361 gacccttttt ctccgatcat ggcgatctcg tccaatttta ttggtgatgg tcatatcttt
    30421 ggcaatttct ccccatacga tggcttgata tctccgatag atcatttttt gttccaacat
    30481 tcttccaagt atcggcaaga caaatggatt ttttgcaaat aaaacggcac cgcttgtttc
    30541 tttgtccaag cggtggacaa cgtaaggtcg ttgctgttta gtgtcgagat aagcagctaa
    30601 atgattgagt aaggtactgt tttctgtcgg ttcatttgga tgagtcttca ttcctgcagg
    30661 cttatccact ataatcaaat gctcatcttc atataaaaca cggatgtgct tcgcatctcc
    30721 taattgaact tcttgataat tataatctgt ttcttcgaat aacaatgtga tctggtcatt
    30781 gccctttact tcatgatgga acaaagcagg ttgttgattg atccaaacgt ttttacgtat
    30841 acgcaaaaag tgtcgaacct ttctaggaac taaccattcc ttttcaagca agtcgcgaat
    30901 tgttgtttca ggatggttca taggtaaagt gatcgtgatt ttcacaagtg tactcctttc
    30961 agtgcaatcg cagactaatt gtaccatttt taaaacatat ttaagaaaaa acttacattt
    31021 ttctgttcat tcttatgtta ctctacttgc actaacgtaa aaaaacatat tgaactacaa
    31081 cttaagcagg aagaaaacac tctttcacta tggtaaaata agacgattga atcaaataga
    31141 caggagaaga agcaaatgga ttttcaaagc attttagaaa agataaaagc tgctttgatc
    31201 agtttttggc gttggatcag accatatctc ggacaattcc atcgatggcg aaagcgcatc
    31261 tggaaaaaat atcatgtgaa caaattgatt ttgctgattg gtttgatctg tgtcttagtg
    31321 acaagtatct acctctttat tttagcaaaa caagcaaatg tcgaaacgtt aaaatcagga
    31381 ttaagccaat cgacagtcat ttatgataag aaaaacgaag aagctggcac actgtacgcc
    31441 caaaaaggaa catatgtaga attaaacgcg atttctccct atatccaaga tgcagtaatc
    31501 tcgacagaag ataggaattt ttacgagcat cacgggtttg atatcaaagg gattgcccgt
    31561 gcagcagtcc gaatggtctt gtctggcgga acatcagggg gcggaggaag tacgatcact
    31621 cagcagcttg ccaaaaatgc gtatctgaca ttagaccaaa cgtttgatcg aaaagcgaag
    31681 gaattatttt tggcaatcga gatcgaaaag aagtacagca aagaagaaat cttgaccatg
    31741 tatcttaaca atgcctattt tggcaacggg gtatggggtg tccaagacgc ttccagaaag
    31801 tattttggag tagatgcaac gaatgttacg ctgtctgagg ctgctacttt ggcaggaatg
    31861 ctgaaaggtc ctggtattta taatccgatc gatcacccaa aaaatgcgaa tgatcggaaa
    31921 aacacagtac taagtgtaat ggaagaaaac ggaaaaatca caaaagaaca agaacaagca
    31981 gaaagccaga cagatatcag cgcgtatctt aatgacacat acgataattc agattctggt
    32041 tatcgttatc cttattattt tgatgcagtg atcgatgaag cagttaacga gtatggtctt
    32101 gatgaagaag atgtcatgaa taaaggctat aaaatctata cagctttaga tcaggattat
    32161 caaaagcaat tagaagctac ttatcaaaac agtgcattat tcccagcaaa tgcttcagat
    32221 ggtgccatgg tccaatctgc ttcagtagct ttagatccga atacaggtgg tgtacaagca
    32281 ctagtaggac gaagaggaga tcatgtcttt agaggattca gctttgctac acagatgcgt
    32341 cgttcaccag gatcaacgat caaaccatta agcgtatata caccagcact ggaagctgga
    32401 tacaagcctt ccagtatctt gaaagacgaa ccgcaaagtt attacgatgc gcataatttt
    32461 gacgggacat accaaggaga agtaccgatg tatcaagctg ttgcacaaag tttgaatttg
    32521 cctactgtat ggcttttgca tgagatcggt ttacaaaaag gatatgataa agcagaagaa
    32581 ttcggcctgc ctttagcaaa atctgataag tattatggct tagcccttgg tggactggaa
    32641 aaaggagtat ctccattgat catggcgggt gcttacagtg catttgccaa tgatggtcag
    32701 atgtatacgc cgcatcttat cacgaaaatc gttgattcga ctggagcggt gatcgtcgat
    32761 aacacaaaca aaaaaccaaa acaggtcata tcaaaggaaa cagccgatga aatgaccagc
    32821 atgcttcttg gtacattttc aaatggaaca gcggctgctg cgaatcctgc aggttatacg
    32881 atagcaggga aaacaggaac cacagaaact aatttcgatg ccacaaaagc aaatgaccaa
    32941 tggatgatcg gttacacgcc agacgtagtg atttcgacat ggatgggtta cgaagaatcc
    33001 agcaagctgc actatttgga agggacaagt ggaaatgttg tcgggaaagt cttcaaatca
    33061 gcggcagaag gcatccttcc gtatacttca aaaacaggat ttagtgtagc agatgcctat
    33121 gccacaggag gacaagtggt agctgcagat caagttggaa acacaggaaa ttctaatgga
    33181 gagtctggaa attggcaaga taacttgaat caatatggtg aacaagcaaa agaagggctg
    33241 aaaaacttcg gcgatatggt gaaagaaggc gttcagggaa ttggtgaagc ggctaaagac
    33301 ctctggcgga aatatcaagg agagtagccc ctttgaaaac gaataacccc atgttacaat
    33361 agagagtaac tactaaaaga aaagagggca taacatgtca aacatctacg atagcgcgaa
    33421 tcaaatcgaa cgtgagatcc gtgaattacc agaattcaaa gcgttgaaag aagcgtacga
    33481 gaaagtacaa gcaaacgaag aagcacacaa actgttcaaa gacttccaag cgatgcaaat
    33541 cgaattacaa gaaaaacaaa tgagtggaca agagttcagc gacgaagatg caatgaaagc
    33601 acaagaaatg gctgtgaaaa tccaatcaga agaagtaatc aatgacttga tgcaaaaaga
    33661 gcaaggcttc agtacaatca tcaatgactt gaaccgtatc atcatgacac cagttcgcga
    33721 cctttacagc gaataaaact attttatgaa acaacagagg gtgtgaaaga gacgttcggc
    33781 cttgagcgat gacaaaattg cttcttattg ccgataggct gtctcttgaa caccatttac
    33841 caagaggtcg tgagcctacc gtttaactct gagttacaag gaacaatttc aaaaaacagc
    33901 ttctcatgtt tgatgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
    33961 attcagaaat aggagctacg acaaaagtct tgtcatagct cct
//
LOCUS       DAPBBV010000031        32535 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.031, whole genome shotgun sequence.
ACCESSION   DAPBBV010000031 DAPBBV010000000
VERSION     DAPBBV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.031"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            133..507
                     /locus_tag="RD486_001821"
     CDS             133..507
                     /locus_tag="RD486_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7663551.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="RD486_001822"
     CDS             complement(621..1250)
                     /locus_tag="RD486_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7663552.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="RD486_001823"
     tRNA            complement(1384..1456)
                     /locus_tag="RD486_001823"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="RD486_001824"
     tRNA            1670..1743
                     /locus_tag="RD486_001824"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
     gene            complement(1881..2045)
                     /locus_tag="RD486_001825"
     CDS             complement(1881..2045)
                     /locus_tag="RD486_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663553.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2340..3668
                     /locus_tag="RD486_001826"
     CDS             2340..3668
                     /locus_tag="RD486_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HDT7663554.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMEAFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3870..4703
                     /locus_tag="RD486_001827"
     CDS             3870..4703
                     /locus_tag="RD486_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDT7663555.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4719..5456
                     /locus_tag="RD486_001828"
     CDS             4719..5456
                     /locus_tag="RD486_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HDT7663556.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5611..6579)
                     /locus_tag="RD486_001829"
     CDS             complement(5611..6579)
                     /locus_tag="RD486_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDT7663557.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6811..7644
                     /locus_tag="RD486_001830"
     CDS             6811..7644
                     /locus_tag="RD486_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDT7663558.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7678..8517
                     /locus_tag="RD486_001831"
     CDS             7678..8517
                     /locus_tag="RD486_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7663559.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8543..9103
                     /locus_tag="RD486_001832"
     CDS             8543..9103
                     /locus_tag="RD486_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7663560.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9302..11023
                     /locus_tag="RD486_001833"
     CDS             9302..11023
                     /locus_tag="RD486_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HDT7663561.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11188..12330
                     /locus_tag="RD486_001834"
     CDS             11188..12330
                     /locus_tag="RD486_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7663562.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12346..13557
                     /gene="thiI"
                     /locus_tag="RD486_001835"
     CDS             12346..13557
                     /gene="thiI"
                     /locus_tag="RD486_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDT7663563.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14130..14777
                     /locus_tag="RD486_001836"
     CDS             14130..14777
                     /locus_tag="RD486_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDT7663564.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14906..15122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15170..17815
                     /locus_tag="RD486_001837"
     CDS             15170..17815
                     /locus_tag="RD486_001837"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDT7663565.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18125..19438
                     /locus_tag="RD486_001838"
     CDS             18125..19438
                     /locus_tag="RD486_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDT7663566.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19428..20081
                     /locus_tag="RD486_001839"
     CDS             19428..20081
                     /locus_tag="RD486_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7663567.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20136..20828
                     /gene="radC"
                     /locus_tag="RD486_001840"
     CDS             20136..20828
                     /gene="radC"
                     /locus_tag="RD486_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDT7663568.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20978..21178
                     /locus_tag="RD486_001841"
     CDS             20978..21178
                     /locus_tag="RD486_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7663569.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21432..23111)
                     /locus_tag="RD486_001842"
     CDS             complement(21432..23111)
                     /locus_tag="RD486_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDT7663570.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23113..23325)
                     /locus_tag="RD486_001843"
     CDS             complement(23113..23325)
                     /locus_tag="RD486_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HDT7663571.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23718..25448
                     /gene="efrA"
                     /locus_tag="RD486_001844"
     CDS             23718..25448
                     /gene="efrA"
                     /locus_tag="RD486_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HDT7663572.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25445..27205
                     /gene="efrB"
                     /locus_tag="RD486_001845"
     CDS             25445..27205
                     /gene="efrB"
                     /locus_tag="RD486_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HDT7663573.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27300..27497
                     /locus_tag="RD486_001846"
     CDS             27300..27497
                     /locus_tag="RD486_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663574.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27650..28135
                     /locus_tag="RD486_001847"
     CDS             27650..28135
                     /locus_tag="RD486_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDT7663575.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="RD486_001848"
     CDS             complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="RD486_001848"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDT7663576.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29012..29539
                     /locus_tag="RD486_001849"
     CDS             29012..29539
                     /locus_tag="RD486_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663577.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29630..30367
                     /locus_tag="RD486_001850"
     CDS             29630..30367
                     /locus_tag="RD486_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDT7663578.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30371..31288
                     /gene="miaA"
                     /locus_tag="RD486_001851"
     CDS             30371..31288
                     /gene="miaA"
                     /locus_tag="RD486_001851"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDT7663579.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31290..32519
                     /gene="hflX"
                     /locus_tag="RD486_001852"
     CDS             31290..32519
                     /gene="hflX"
                     /locus_tag="RD486_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDT7663580.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10771 a         5522 c         6876 g         9366 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aatccaatca cttgggtttc tttttctttt
     1801 attattatga tgaatcaagc tttctgtttt tgtcacgtat gttgtaatct ttacgaaaga
     1861 gtagagttgg ctactcataa tcaaccatac ttcccatcat cgctaaatac gaaataaatc
     1921 agcattccta caccaatcaa agcacaagct gcaccaagaa aagggatgac attcccaaag
     1981 ttatctgtat tcataagtat gccaccaccc acaaacaaaa agccgccagc aatcaggttt
     2041 ttcattttat tcatctcctt tcttacgtta tagtatttcc ttctttcaat gagtattttg
     2101 aaagctatct tattgtatga tgttcttcta ggcctcttct ttattataca ggccattttc
     2161 gttatctcat agaaatattc ctttttatct gaaaactatt gtataccgta tgacattttt
     2221 cttcatgaag ttgtaagtat attctcattc aaatgaaaat ttcatcatag aagagattgt
     2281 atttctaaat tcttaagagt aaaatacgaa gtataacttg gatttggaag gatgattgga
     2341 tgaaagctat tacgcctgat atgacaacaa aatttaacaa acagtttcaa gcaaatatca
     2401 aacagcaggc attgcagcgg gcagttgtga agaacggaat tactgcttct gctgaaaatg
     2461 tttcagcaca tgtggagaat acaccggtat tttctataga tttggctacg gggaaagtgg
     2521 ctaatcaaat gcaatcgggg cgttgctgga tgtttgctgc actgaacaca ttccgtcata
     2581 agatgctgaa tcaattccat ttaaaagagt ttgaattatc acaaaattac acttttttct
     2641 gggataaata tgaaaaggca aattatttct atgaaaacat cattgcaaca ggaaaagagg
     2701 caatcgatag ccggaaagta gctttcttac tcgctactcc tcaacaagat ggcggccaat
     2761 gggatatgat cgtttcatta ttccaaaaat atggcgttgt gcctaaatcg gtgatgccgg
     2821 aaagtgcgaa tagttcaaat tctcgagatt tgaataacta cttgaacaaa ttactgcgta
     2881 aagatgcagt agtgttacgg aaaatggttg ctcaaggaga aacattagac gctattgaag
     2941 aaaagaaaga agaaatgcta gaaagcattt ataacttctt agctatctca ttaggaacac
     3001 ctccaaaaga attcgatttt gagtaccgcg atgaagaaaa gaactatcat cttgaccgag
     3061 gactgacacc acaaattttt tatgataaat acatcggtgt aaaattagat gattatgtta
     3121 gcgtgatcaa tgcaccaaca aaagacaaac cattcaatcg ttcttataca gtagagatgc
     3181 taggaaatgt cgttggcggg aaagaagtca aatatctgaa tgttgatatg gaagctttca
     3241 aaaaattagc gattgctcag cttgaagaag gagaatctgt ttggtttggt tgtgatgtag
     3301 gtcaatcttc tactagaact agtggcatca tggccttaga tgcttattca atggatgatc
     3361 tatttgatac ggattttaca atgactaaag ctgaacgttt agattttgga gaaagtctga
     3421 tgacccatgc gatggtattg accggtgttg acttagtaga cgggcaatca acaaaatgga
     3481 aagtcgaaaa tagctggggc gaaaaagttg gaaagaatgg cttctttgtt atgagtgatg
     3541 cctggatgga cgaatatacg taccaaatcg ttgtaagaaa agatttattg acgaaagagc
     3601 aattaaatgc gttcaatgaa gaaccaattg ttctatctcc gtgggatcca atgggtgctt
     3661 tagcatagac gagtatttca atgaagagta tgtagtaaag ataaaaagag ctggcttaag
     3721 ccagctcttt ttatctttaa agtccattcc ctgtttttta tggtccctgt gctataattc
     3781 taaataaagg ataaggattg gaaataatcc ttttatcatt aaaaatatga tgacgaagta
     3841 gaataaaatt gggagtaggg gggaaagtca tggatatcca aactgtttta tctgatctga
     3901 aattaaatgg taaagtgatt ccagttgttg gtggcgatgt taatcagacc tatcgtataa
     3961 aaaccgaaca tcgtgcttat tttttaaaaa tccatccgaa tgtaaaaaaa ggattttttg
     4021 aagcagaagt agacggatta aaagaactgt cagcattcgt acgtgtaccg gatacgtata
     4081 tgctaggtga aacaagtgaa ggcgcttatt tgttaatgga atggatcgag ccgggaaaag
     4141 gggatcaacg agatcttgct gcagctttag ctaatctcca tcagcaaaca gcgccacaat
     4201 ttggttttcg taaagataac tatttgggta cacttgttca gaaaaattct tttgaagaag
     4261 attggtggac ttttttcttt aaagatcggc ttgaatccca gatttctttg gcagaagaaa
     4321 cgaatcgatg gaatgtacag cgtcaagaaa agtatctgcg atttaaagaa cgtgtattga
     4381 aatcggttga accaaaaaag atcactccac gcctcttgca cggagacctg tggagtggta
     4441 atgtgttctt tgaccagcaa gggcatccag tttttgtcga cccagctgtt tcttatggga
     4501 atcgggaaca agatattgca atgagccagt tattcggtgg tttccgaccg gaatttttag
     4561 atgcttatca aactatattt ccattagaaa agggatggaa agaccgactg ccgatttacc
     4621 agttatatta tcttttggca catttgaata tgtttggaga aagttacggt tcccaagtag
     4681 atcaattact agaaaatttt taagaggagg gcgtgttttt ggcaaaaaaa tataccaaaa
     4741 agcatgaagt ttcatattat gagtgtgaca tcaaccaaac gatgacattt ccttcgatgt
     4801 taggagtagt tatcaaaacg tctgaagatc aaagcgacca gttgggaaga ggcagtgaat
     4861 tcgtcaatag ctttggactt acttgggtca tcacgaatta ttccatggag attaatcgtc
     4921 tccctagagt cggtgaagta atctcagtaa cgactcaagc catggagtac aataagtttt
     4981 tctgttatcg gaacttctgg atccatgatg aagatgggaa agaattagtc aaaatagaat
     5041 ctgttttcgt attgatggat tttgtgaatc gaaaaatgag cagtgttaat gaagagatca
     5101 ttgctccttt tgagagtgag aagatcaaga aaatcaagcg tcaggaaaaa attgaaaaga
     5161 ttgattcggg cttcatgttg ccatatcgtg ttcgttttta tgatatcgat agtaatcagc
     5221 atgttaataa tgcgatgtat tttaattgga tcattgacgt attaggatat gactttttga
     5281 ctacgcatgt tccagaaaaa gtaattattc gatttgataa agaagtagag tacgggaatg
     5341 agatcgaaag ccattttgaa caaatcccta tcgaaaatgg tgtcaaaaca aaacatgaaa
     5401 tccgaatgca agaacagctg tattgtgaag caaatattat atggaaaaat aaataaaaaa
     5461 gaggttgtga cagaaggggg caacttcaag aaataagaag aaatttacga aaattgtttc
     5521 tcaaattttt gtaaattttc gacttagttt tcgaagaagc tatttttgtc acagcctctc
     5581 tttttaagtt tagctattag ataatgatgt ttagttttgg ataaacgaaa tcaattcttc
     5641 acccgacaaa ccatagttta cagcaatcaa tagttttaaa cgtgcttttt gactattaat
     5701 actgttacag aaaataatcc ccattttttc tagttctttt cccccgcctt cataatcata
     5761 aacaggctct gcgattccat tgaaacaacg agaaacaagt actacaggga ttttttggac
     5821 aagaagcttt tccaaagcag ctaaggcttg tggagggaga ttccccgcac ctaaagcttc
     5881 gattaccaaa ccgtctactt tcgtatgggc gatggcttcc aataagtccc cttgcatccc
     5941 agcatatgct ttaacgatcg ggatagtccc atctacagcg gaaatgtcca gtcgctttgt
     6001 ttctaaaagt tcctgcaaga ataaaattcg attcttagtt actaagccga tgggacccaa
     6061 tgtaggtgtt cggaaagtag caacatttgt ggtatgggtc tttgtcacgt agcgtgcaga
     6121 atggatctca tcgttcatga ccaccaaaac ccccttatct agcgcttctt cacaacttgc
     6181 gacacgaatc gcactttcaa aattataaag gccgtcactt ccaagttcat tacttgaacg
     6241 cattgcccca gtcaaaacaa ttggtaattt gttgccaatc gttgtatcaa gaaaaaaagc
     6301 agtttcttct aatgtatctg taccgtgtgt gatcaccact ccggatatac ctgatgcata
     6361 agcggacaag atacgttctt ttaataccaa catgtgagaa ggcatgatgt gtggtgaggg
     6421 aagattgaag atatcttcaa ctaataattc tacatgcttg gggattgtga tttctgcatc
     6481 taataatggg tttgccacat caggactaac accgcccgtg agcatgtttt ctttcatggc
     6541 gatcgttccg ccggtgtgta gtacaagtat ttttttcatt ttacagactt ccttacgaat
     6601 aattttgcat agccgttaaa tcttattgta tactatataa aagagttttg ctatcagtga
     6661 agaataacga atagcctaac ttatcataaa aaagctgacc ttattaaaat ggaaaagact
     6721 caaccttgac ctcctaatac aatggagtat ctggttgagt ttcttttaca agaaagcagc
     6781 caaggaaatc aatcacgaag gtggccggaa atgatcagaa tcggattaac atcgtttaaa
     6841 gaacatgaca aattaactgg taaaaagaat aacactcttt atgaatatgc agggtttcta
     6901 cccttagtgg aattagatac tgcctattat ggaattcccc gaaagtcctc agttgagaat
     6961 tggataagtg aagtacctga atcatttcgc tttgtagtca aagtctatca aggaatcagc
     7021 ggtcaaggag actggaagcc ttattatcag accgaagaag agatgattgc gcatttttta
     7081 gatgttatgt cgccaatggt agatgctgga aagatgtttt gctttttagt ccaattcccc
     7141 tcatcattca aatgtacgaa agaaaatgtc cagtacttgc gcaaacttag aaagtggttt
     7201 gagggttatc ctgtttctat agaattgcgg gattattctt ggtacagcga tgaatttctt
     7261 gaacgtacaa gaaactttat gtctagagcc gctttttctt tagccatcat cgatgagcca
     7321 cagttgctga atacaacgat tccttttgat ccatttgtca ccaatccgaa ctttgctctt
     7381 tttcgattcc atggtaggaa tgcgcaagga tggcaagcaa atgataaaga gtggcgtaaa
     7441 aaaagaacgt tatatcgtta ttcagaaaaa gaactgcaag aactagcaca tgaagtcaaa
     7501 gtagttgatt ctaagacaaa agaggtaggt gtgattttta ataataattc tggtggtgat
     7561 gcggctgaaa atgcattagc actgcaaaaa atattaaata tcaagccaga tggactcaat
     7621 ccaacccaaa tggatctgtt ttaagggctt attttattca agaaaggggc gaagtctatg
     7681 atcaaagcta ttttttttga tattgacgga acattggtca ccaatcgttc aaaagcgttg
     7741 gaatcaacaa aacaagcaat tgaatatgct cggaaaaacg gcattttatg cggtgtagca
     7801 acggggcgca gcccagtaaa gatcaaagaa atcattgatg aattggaatt agatatgtat
     7861 gtcgtgtata atggtcaact ggtttttact gcagatcgca cgattatcga ccaccctttt
     7921 gaacaaaaag tattggaaca tattgttgaa tttgcagatg agaaccatcg acaaatcgtt
     7981 tttggtgcga gaaatcggtt agatggatca acgacgatgc tattaggaca atcgattttt
     8041 atcaagcgac tagtcagctt tttaccgcgt aaattcccgg tacgtctgat gaaaaaaatc
     8101 ctccaggttt ttagccctca ccgacaaaag gatcgttatg aaacgttaga gatattaaaa
     8161 gaaccaattt atcaatgtat attgctcagt ccggagtcag aacagaaaaa gttagaacat
     8221 cgctttcccg agtgtacgtt tcagcgttca aatacgtata ctgtagatat catcccaaaa
     8281 ggtggttcaa aattactagg catccaagct ttcgcaaatg ctgtcgaaat tgaaatggaa
     8341 gaaattatgg cattcggcga tcattacaat gatatcgaga tgctgaaagg tgtaggaatt
     8401 ggagtggcca tggggaatgc tcagatcgaa gtaaaacatg ctgcagactt tgtgactcaa
     8461 tcaaatgaag aagatgggat atacgaagga ctgaaacact tcggtctgat ttattagtca
     8521 atgaaagaag gaaaaaatca gtatggaagc agagacacct tttcaaaaag tagaaacatt
     8581 ccacaaaact tttgatccaa gaagaccaga gatacccacg gcttttacag aaaatgaagc
     8641 tcatacacgt gctgcgttca aaatagaaga acttgttgaa tttgttgcag ctacttcacc
     8701 taataaagaa caactgcatg aagctgttat gctgctgcac gaagcattag ataaagcaga
     8761 agaaaaaata cttggtaaaa cacagtgggg aagtgatccg ctggttgaac aagtagatgc
     8821 actgacagat atcctttact ttacttatgg ttctttttca ttactaggaa tagtgcctga
     8881 tcgaatattc gaaatcgtcc atcaggcaaa tatggggaaa ttatttccag atggaaaacc
     8941 tcattatgac cctgtaacaa ataaagtgtt gaaacctgaa aactggcaga tggaatatgc
     9001 tccagaacct aaaatcgcgg cagaaatcca acgtcagatt caagaagcga ttgctaagaa
     9061 gaaatccgct gatataggca tgtgcacaaa tgaaaaagag tgatcagagt ttcactattt
     9121 ttgttatctt tatacgatgg aaaaacaaaa gattttcgtt taagttagtg aatgcatgaa
     9181 aatagtatgc tataatctag aatagatgtc ttttgcacga gagacgtatt atttggattt
     9241 atgccaagca gaacgccatc tgttgcataa aagatgcata ctgaaaacgg aggaaccata
     9301 aatgggaaat aatgttatca tcggaatcgt cattgcaatc attatagtcg ccattgtcgt
     9361 ctttttggtt agttacttga tgaagaaaaa aaaccaagat cgattggatg ccttagaaaa
     9421 acgcaaggaa gaattatttg acttgccagt gattgaagaa gtcgatgatg ttaaaaaaat
     9481 gcatctggtt gggcaaagcc aaaatacctt tcgtgaatgg agtcaaaaat ggaatgacat
     9541 atctacttcc tcgttcgctg aactagaaag tcaaattttc gaagtggaaa acctcaatga
     9601 aagttttcgg ttcttaaaag gaaaaaaagc agttgttgaa gcagaagcta caatggacca
     9661 aatggagaaa caagtgacgg aaatccgtga aggtctaaag gaattgcggg aaacggaaga
     9721 acgcaactca ctagctgttc agcaggcact tgacgtctat gaagaactga aagaaaaagt
     9781 cagagaagac gagcatgaat acggaccagc tctttttgaa ttgcaaaaac agatcaaagt
     9841 gatcgaaaaa gaatttacgc agtttgtgac tttaaacact tctggagacc ctgttgaagc
     9901 ccgcgaggtt ttggataaag cagaaaaaca tacgtatgaa gtggaagctc tgatgaaaaa
     9961 aattccaccg ctgtatgagg agctccatac cactttccct gaacaacttg aagaaatcag
    10021 tgatacttac gagaaattga tggaagaaca atatgtattc ccagaagaag atcttgctga
    10081 agatatcgca aaagtaagtc gaagaattga aaattcatta gccaatcttg aaaaaacaga
    10141 agttgaaacg gtcgaatttg aaaaccgtga aacagctgat ttgattgatt cgttatatga
    10201 tatcttagaa cgggaaatgg aagctcagag atatgtaaaa actaaccaat caacgattgc
    10261 agagtatatc aaacatacaa caaagaataa ccgtcaatta ttgattgagc tggatcacac
    10321 atctcaaagc tatacattga accacaatga aattggccgt gtacgaggtt tccaaaccga
    10381 agtggaagaa atggaacgtc aaaatgaaca gatgattcca cagatccgtc aacacgaaat
    10441 tccttattca gaagtgcgca cgttctataa aacagtcttc aaagtcttag aagatatcga
    10501 aaagcaacaa gtagagatcg acgactcatt acatgaattg agaaaaggcg aaaaagaagc
    10561 gcaagaaaag atcgatacat tcgaattcaa attgcgcagt ttgaaacgtt ttgtagaaaa
    10621 acaacgtttg cctggcttgc cgaatgatta cctagaattc ttttttgttg ctactgaccg
    10681 tattgaagaa ctaagtgttg tcttgaataa aattcgagta aacatggaag aggtcaatcg
    10741 tttagttgct ctatgtgaag aagatctaga attattagat aagaagacac atgatttagt
    10801 agatgcagca gcattaacgg agcaaatgct ccaatatgca aatcgttatc gtcatacaca
    10861 cgaagaagtg agagaagcaa ttgataaaag ctactattta ttcaataaag aatatcacta
    10921 tcaagaagca ttagacgaaa tcggtacagc attagagcga gtagaacctg gtgctttcaa
    10981 acgcatcgaa gatttttatt ttaatcatcc agacttagta taaagcaaaa aagttagtaa
    11041 accagcaaga gcaagacgga ttattgtctt gttcttgtct ttttttgtat atttgaaaat
    11101 tgaaacaagt gaaaatttca cctgctcttg aaagcacctt ggacaaccgt tataatagaa
    11161 aagaatttca aaaaagaggg gtttcttatg atatattttg ataacagtgc aacaacccca
    11221 atctttccgc aaagcttaga tgcatatgta aaaaccagtc agcggattat tgggaatcca
    11281 tcaagcttgc atgatttagg caatcaagct aaccggttgt tgcagcaagc aagaaagcag
    11341 atcgctgatt tgatccatgt agaaccagaa gaaatctatt ttacttcagg cggaacagaa
    11401 ggagataact gggtattaaa aggaacgatg atcgaaaaaa gagaatatgg gaatcatatg
    11461 atcatttcag gagtcgaaca tccggccgtc agcgagacag cagaacaatt aaaagaatta
    11521 ggaatcgaag taagtatcgc cccagtggat aaacgcggat ttgtacgtgt cgacgaattg
    11581 aaagaattaa taagaaaaga gacagtatta gtctctgtta tggctgtgaa taatgaagta
    11641 ggatcgattc agcccatcca ggaaatcagt gatcttttgg atgattttcc taaaattcat
    11701 ttccatgtag atgctgttca ggcgattgga aaagtaccat tctcgcaatg gttgacagaa
    11761 agagttgatt ttgcaacatt ttcagctcat aaattccatg gcccacgggg aactggtttc
    11821 atttattgga aaaagggtcg tcgtttagca ccattactga caggtggagg gcaagaaaga
    11881 aatcagcgaa gtgggacaga aaatgttcca ggtattgtgg ctatggttaa agctttacgt
    11941 ttatcattag agataaagga acaaaaacct gagcagacac aacgcttaaa agtagctcta
    12001 atcaatgcgt tgaagacgta tgagaaagtg acgatttttt cagaaggaac tgactatgca
    12061 ccgcatattt tatgttttgc tctaaaagga attcgcggcg aagttctcgt ccatgcctta
    12121 gaagaaaaac aaatatttgt ttctactact agtgcctgct cctcacgtaa acatatggca
    12181 agcagtacat tgcacgcaat gcatgtacca aatgatctgg ctacatctgc tgttcgaatc
    12241 agcttagatg aaaacaattc gcttgcagaa gtcgagcaat ttatgattat tttcaagcag
    12301 ctttataaga aattttctgc aatcaattaa aagaggagtg ttcttgtgaa atacagtgaa
    12361 attatggtcc gttatgggga actttcgaca aaaggaaaga atcgaaaaag ctttatcatg
    12421 caactagcac aaaatgtcag acaagctttg aaagactttc cagaaatcaa aatccatgct
    12481 gatcgggacc ggatgcatct tttattgaat ggcgcagacg ggcagctagt tattccaaaa
    12541 ctagcaaaaa tatttgggat ccaaaatttc tctccaagta ttcgtgtaga aaaagatgtc
    12601 gaagttttga aacaagctgt tcaagacatc atgaaagaaa tttatactgg gaaagaaaca
    12661 tttaaaatta tcgctaaaag aagcgatcac caatttgaat tgacaagtaa tgaattgaat
    12721 caaacattag gtaatgctgt ttttgatatt ttcccgcata tccaagttca aatgcgtcaa
    12781 ccagatattc cattacgtgt agagattcgg cgtgatggcg cttatctatc gtatgaaacg
    12841 atcaagggag ctggaggatt gcccgtagga acaagcggaa aaggaatgct tatgctttct
    12901 ggggggattg attctcctgt agcagggtac tttgccatga agcggggagt ggaaattgaa
    12961 gctgttcatt ttgctagtcc gccgtataca agtgaacaag cactgcaaaa agcaaaagat
    13021 ctaacagcca aactagcacc ttatgtggga acgatccatt ttatcgaagt gccatttacc
    13081 gagattcaag aagaaatcaa aaagtcagtg ccacaaggat attggatgac aattactcgt
    13141 cgaatgatgt tgcgtttgac cgatgaaatt cgccgtattc gtcatggttt agtcattttg
    13201 aatggtgaat cattaggtca agtggcttca caaactttgc aaagtatggt ggctatcaat
    13261 gaagtaacga atacgccaat cattcggcct gtagcgacaa tggataaact tgaaatcatt
    13321 gaagtagcag aacagatcga tacatttaat ctttctatcc agccttttga agattgctgt
    13381 acgatttttg ctcctccaca gccaaaaaca cgccctcaac tggaaaaggt ccatcaatat
    13441 gaagagcgtt tagcaataga tgaaatgatc caacgagcac tagctggctt gaagatggaa
    13501 gagatacaag cagaatcgtc taatgaaaaa actgaagaat tttcagaatt gctataagag
    13561 gttatgaaaa tagtgttttg accagagtat tagagaaaca aaacgaaaaa atagctccat
    13621 gtattttacc gtttttgaac taatgtcgaa gattagctga ttgaatacca tttatcaaga
    13681 agttatggaa aagccggttc ttttttacta actgaaaaat aaaattttat ttagagatca
    13741 agctacagtt gataaatgat ataaaaaaga gaatttccca tgaaatagcg aggttgtgac
    13801 agaagtgggc agcttcaaga aataagaagg aatttacgaa aattgctttt caaatttttg
    13861 tgaaatttcg gcttattttt cgaagaagtt acttctggaa caccgtgtat cagaggttgc
    13921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt
    13981 tacgtttggt tgagcttatt accgcagatg caagcttttg aacaccgttt tatttgtctc
    14041 acaccctttt ccttcctact tgtaaccttg ctcccgtgtt agaaacatgt tacactaaat
    14101 atgtgaaatt attaacaagg agcgtcgtta tgcgagaaaa aacagataca ctgccaaaag
    14161 caactgcgaa aagattacct ttatatttac gctacttgaa gatgctggat gactcaggta
    14221 taagtagaat caaatcaaat gagttcagcg aaatcaccca aattccttct gcaacgatcc
    14281 gcagagactt ctcgcaatta ggcgagctag gcagaagcgg atatggctat gatgtccctt
    14341 ttcttatcga tgtattcaat aatatcctta atactaaaga agaaaaacga atcgcattag
    14401 taggatatgg aaatcttggc aaagcattga aacacaacaa ttttagaaga aatgaaaatc
    14461 taaatatcgt gtgcgtcttt gataatgatc cagcactgat caatcgagta attgatggag
    14521 aaatgatcta tccgattgat cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag
    14581 caatctctac ggtaccaagt aaatattcac aatctgctat tgatgaaatt gtcaaaggaa
    14641 atgtaaccgc tatacttaat tttgcgcctg acagagtaac tgtcccagct tatgtcaatg
    14701 ttcaatacat tgatttgaca accgagttgc agacgcttat ttactttgat gagaattact
    14761 cagaagtttt ttcttaggaa aatttgagta ggcttattga tcttgcgaga actcgtcgta
    14821 attctttcaa aaatttttta gtactaaatg aagtggtttt ttcacgacca cttgttgact
    14881 aaaaaaaaaa accattgtag aatgaagcat aacgctgaac aagaggagta actggcacat
    14941 tcattcttag agagagaact atctgctgaa aggttctcaa tgacaaccag tgaaggtagc
    15001 ttgggagttt ctgtcttgaa tggagtagag atagacgagt cgtgatcgtt aactcacttg
    15061 agaggcaata atgattgatt attgcaattt aggtggtacc gcgtaaatca tacgtcctag
    15121 aatacgaaag tattttagga cgttttttag tttaaaggag gaaaacagca tgacggaaga
    15181 aaataaccta tcaacaaaat ataatccgca agaagttgaa gctggacgtt atcagcattg
    15241 gttagaacaa gatttgttta aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt
    15301 aatcccgccc ccaaatgtta ctggaaaact tcatttaggg catgcttggg atacgacctt
    15361 gcaagatatg ctgattcgtc aaaagagaat gcaaggatat gatactttat ggctgcctgg
    15421 tatggaccat gcaggaatcg cgacacaagc aaaagtagaa gcgaagctta gagagcaagg
    15481 gatttctcgt tatgatctag gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga
    15541 agagtatgcg agccacatcc gcgaacagtg ggctaaaatg ggcttatctt tagattacag
    15601 tagggaacgt tttacattag atgatggatt atctgaagca gtacgtaaag tttttgttac
    15661 cttatacgaa aaaggtttga tttatcgtgg tgaatatatc atcaactggg atcctcaagc
    15721 acgaacagct ctatctgata tcgaagttat tcataaagat atcgaaggcg ccttttatca
    15781 tatgagctat gaactagcag atggatcagg cgtagtagaa attgcgacaa cccgtccaga
    15841 aacgatgttg ggagatacgg cgattgctgt tcatccagaa gacgagcgtt atcaagcgct
    15901 catcggcaaa aaagtgattc tacctttagt caataaacaa atcccaatca ttgcagatga
    15961 atatgtagat atggaattcg ggacaggtgt agtaaaaatc actccagcac atgatccaaa
    16021 cgactttgag gtaggtaatc gtcatgatct tccacgcgta aatgttatgg atgatgatgg
    16081 tacgatgaat gaactagcag gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc
    16141 aatcgtgcaa gatctgaaag aaatcggtcg attgattaaa atcgatacga tgatccacag
    16201 tgtgggtcat tccgagcgga caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt
    16261 tgtaaaaatg gcgccgttag cgaaaaaagc cattgataac caagaaacag atcaagcagt
    16321 ggaattcttc cctccaagat tcaatcaaac gtttttacgt tggatggaaa atgtccatga
    16381 ttgggtaatc tcacgacaat tatggtgggg acatcaaatt cctgcatggt atcacaaaga
    16441 aacaggtgaa atgtatgtag ggatggaagc accagcggat agtgaaaact gggtacaaga
    16501 tcctgatgtt ttagacactt ggtttagttc agctttgtgg cctttctcaa caatgggctg
    16561 gccagatacg gaaagcgaag attataagcg atacttccct actagcactt tagtaaccgg
    16621 ttatgacatc attttcttct gggtaagcag aatgattttc caaagcttgg aatttactgg
    16681 cgaacgtcca tttgagaatg tcttgattca tggattgatt cgtgacgaac aagggcggaa
    16741 gatgagtaaa tcattaggta atggaatcga tccgatggaa gtaatcgaaa agtatggagc
    16801 agatgctctc cgctggttct tatcgaatgg ttctgcacca ggacaagatg tccgcttcag
    16861 ctatgaaaaa atggatgctt cttggaactt tatcaacaaa atctggaatg cttcacgttt
    16921 cgttatcatg aatatcgaag gaatgaccgt agaagagatc gatttatctg gagaaaaatc
    16981 agtggctgac cggtggatcc ttactcgttt gaatgaaacg atcgaacgag taactgagct
    17041 atttgatcgt tttgaatttg gtgaagcagg tcgacaactg tataacttta tctgggatga
    17101 tttttgtgac tggtacatcg aaatgagtaa agaagtactt tatggagatg atgctgtttc
    17161 aaaacaaacc acccgtagca tcttagtcca tacacttgat cagatcctac gtttattgca
    17221 tccaatcatg ccattcgtta cagaagaaat atgggaacat attcctcatc agggaaattc
    17281 tctagtagtg gcagaatatc ctgttgtacg tccagagttt gatgatgaaa cagcttctaa
    17341 agggatggaa gtattgaaag aattgattcg agccgttcga aatattcgtt cagaagtgaa
    17401 tacaccattg tctaaaccaa ttacgttgct aattaaaaca aacgatgcta aaatcgatca
    17461 atttttagtt gaaaatacaa gctatatcga acgcttctgt aatcccgaag agttgacgat
    17521 atcaagtgag atcactgcgc cagatctagc gatgtcagct gttctgacag gtgcagaaat
    17581 cttcttgccg ttagcaggat tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga
    17641 actggaaaag tggacaagcg aagtaaaacg tgtccaagga aaactttcta atgaacgttt
    17701 tgtttctaac gcgccggaag aagtagtaga ggcagagcgt gcaaaagaaa aagattattt
    17761 agagaagcaa acggctgtca aagaacgaat cgaaagtttg cgtactattc aataagaata
    17821 gaaaaagaga gtgtgaaatc agctagctat tactaaaagc tagctgattg aacatcgtta
    17881 caggaaagag tttgagcctc actcttagct tcgattcata aggagatgtg acataaattt
    17941 tgtcgcatct cttttttagt ctactcttat tatgtaggag aaggagggag gtggatcatg
    18001 tatcaagagt caataaagta gttgataaaa tcgttcctct ctctgtttct tttctctttg
    18061 tcatactttt atttttctta tgtgttctat ttgttataat aaaagagaaa tgggggaatt
    18121 gttgatgacg attgaagaag caatagaatg gatccatagt cgattaccat ttggttcacg
    18181 tcctggcctt gaccgagtcg aagctttatt agaagtggta gggcatccag agagaaaagt
    18241 aaaaacgatc catatcgctg gaacaaacgg aaaaggttct actgtagctt atttgagaag
    18301 cctattagaa gaggctgggc tgacagtagg tacatttact tcaccttata tcgaaacgtt
    18361 caatgaacgg atcgcaatca atggcaaaag cattccagac aatgatttga tccagcttgt
    18421 aaaaaaatat cagccactga tcaaacaact tgatcaattt gaagcagtag ctggtattac
    18481 tgaattcgag acattaacag caatggcatt tgattatttt ttgatgaaga aagtggacgt
    18541 agcgattatc gaagttggct taggcggctt attggattct accaatgtag ctgtaccaat
    18601 gctgacggga ataacaacga ttggacttga tcataccgaa atacttggag atacaattga
    18661 agaaatcgct gcacaaaaag ctggaatcat caaacaaggc gttccagtag taacaggaaa
    18721 tattgcccca gaagctttta ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct
    18781 ttatgtatac ggggaaaatt ataaaataaa ctatctgcat cctgatgaga tgtggggaga
    18841 agtatttgaa ttttttaatg aaataggaaa gatccctcaa ttaaccactc cgcttttagg
    18901 gcaacatcaa gctgaaaatg caggagtagc catcgaattg tattttgttt actgtcaatt
    18961 ggaaaagctg cctttccgag aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc
    19021 aggaagaatg gagcgtttga gtaacgagcc attagttgtt ttagatggtg cccataatac
    19081 gcatgcaatg aaccggcttg ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa
    19141 cattttgttt tccgccttac gaactaaaaa tgttagagaa atgctagaac gattgcagca
    19201 agtaccaaat gtccatattt atttgacgac ctttgaacat ccaaaagcca tcgaattaag
    19261 tgaagtatca gatttagcaa gtgagagagt atcaatcgtt tcattgtggc aattcggatt
    19321 agcagatata ttggaaaaga tgacaaatga agacgtatta gttgtgaccg gttcacttta
    19381 tttcatttca gaagttcgcc atttattaat acaattagga ggagatcatg aagtataatg
    19441 cagtgatttt tgacatggat ggtttgctgt tcgacacaga gttagtgtat tacgaagcca
    19501 cacaagtagt agcagacaag atgggttttc cttatgataa agacctgtat ttaaaattct
    19561 taggtgtttc agatgaagaa gtatgggcga attatcatat gattttctcg gaatttggca
    19621 aaacaagtgt acaaagattc atagatgatt cataccagga aacgcttgaa cgtttttcgc
    19681 aaggagcggt acaaatgaag cccggtgtgt tggaactcct ctctttttta gaagaacatc
    19741 agattcccaa agttgtcgct tccagtaacc aacgagcagt cattgaactt ttattgaaga
    19801 agaacaatct gtttgaacga tttgagacga ttgtttctgc agaaaatgtt caacgagcaa
    19861 aaccagaccc agaaattttc ttgttagcta atcagaagct aggtacagcg aagaaagaaa
    19921 cattgatttt agaagattca caaaatggta ttttagcagc ttctgcggct gagatcccgg
    19981 tagtcatggt accagatctg cttccaccat cccaagaatt gatcaaaaaa acagctgggg
    20041 ttgtttcttc tttacatgaa atccctgcat tgttaaaata aaaatccatc tcttttcgta
    20101 tcttatttta gataagatag aaaggagatg tttttttggg aaaacgattg atcaaagaag
    20161 tacctactag ctctttacca agggaacgta tggaaattta tggcgcggaa gctttatcgg
    20221 atcaggagct tttggcaatc ttactgcgta ccggtcaaca cccttatagt gtgatgtcga
    20281 ttgctggaaa tctgttaaaa acgtttggag gactggcctc tttacgacag gctactttgc
    20341 atgagttaga agagattcga gggataggac gcgtgaaagc aatcgaaatc aaagccttga
    20401 tcgaattagg tcgacgaatt cagacggatc atgaaagagc ggctccaccg gttcgtacca
    20461 gctacgaatt ggcccagcaa ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg
    20521 tttgtattta tttggacacg aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt
    20581 cgctgaatca gtcagtcgct catcctagag aaattttcca ttatgctgta cgttattgtg
    20641 cagcaaggat cgttttagcg cataatcatc cttctggtaa tgttattcca tcgcagcagg
    20701 atatgaattt taccaaaagg atacaaaagt gtggagaaat gatggggatc actgtactgg
    20761 accacttgat catcggacgc aaacgatatt ttagtttgag agaagaagga atgatggaag
    20821 agaagtaagt tgctttcttg caaaaaaaat gaagcaagtg tacaattata ttgtaatttt
    20881 gtttgggaat agaagttgaa acatctgttg cacctctatc gtacacgagc aatgttacaa
    20941 tttaaattag tgcttttggc acgaggagga tattattatg gaaaacggaa cagtaaaatg
    21001 gttcaacgct gaaaaaggat ttggatttat ctcacgtgaa gatggaagcg acgtattcgt
    21061 tcacttctca gctatccaag gtgacggatt caaaacatta gaagaaggtc aagcagtgac
    21121 tttcgacgtt gaagaatcag accgcggccc acaagctgca aacgttgtaa aagcttaatt
    21181 ttatctgtaa atcaaattga tggtagacat caatttttac gagagaacaa agcgagtaac
    21241 aaaaatacct gccacaagag acaatttctc ttgtggcagg tatttttttg tatgaaaaag
    21301 taaataaatt taagaggcta tgaaagagcc accttgtatc aaggaataag aacaaacaaa
    21361 aatggcttct catgtttttc atttgttttc tcttatattc aggacaaggt gctgatttca
    21421 taacctctta tttattcttc atctggtgtc attaccattg gcaaaatcat tggatgtctt
    21481 tctgtacgtt cgaataagaa aggctgaagc gcgccagtca tcgcttcttt caatttatat
    21541 tctgaacagt caggtccatt caaacattct cttaaagcgt ggaataagat tcgctgagct
    21601 tcattgatca tttctcctga ttctcgcatg tagacaaatc cacgagagag aatatctgga
    21661 ccagccaaga tttctttttt cttgatatcc actgtcgcga cagctaatac aagaccttct
    21721 tctgaaagca ggtgacggtc acgtaaaacg acattaccaa tatcaccgat cccgctacca
    21781 tcgatataca catctccagc cacaaaatgc ccagcaggac gcgcagaatc gctagttaac
    21841 gctaaaacat cgccattttc catgatgaag cagttttctg caggaacacc tacatcttgt
    21901 gctagagaag catgtacttt caacatgcgg aattctccgt ggacaggaat aaaatatttt
    21961 ggcttcatca aacgaagcat taatttttgt tcttcttgtc caccgtgacc ggaagtatgg
    22021 atgttattga tttttccgtg aatcacttct gcaccagctt cagacagcaa attgatcaaa
    22081 tgattgacac ttgttgtatt accaggaata ggtgaacttg aaaagatcac tgtatcgtct
    22141 ggctggattt ggatttgacg gtgagtacca ttcgcgatgc ggctcaacgc ggccatcgct
    22201 tctccttgag aacctgtaca taggatcatc gtttcattgg caggcaagcg attgatttcg
    22261 tgtgcatcta caaatgtgcc gtctggaact ttgatatatc ctaaacgttg accgttgacg
    22321 atggcatttt ccatgcttcg tccgaaaaca gcgattttac gaccagttgc cacagcggca
    22381 tctgctgctt gctgcaaacg gaagatgtta gaagcaaagc tggcaaaaat gatacgtcct
    22441 tcgatttttg aaaagatctt caaaatagaa tgcccaatcg ttttttctga tttagtaaat
    22501 gttggaatct cagcatttgt actatcagat aaaaggcaca agactccttc ttccccgata
    22561 cgagccattt tatgcaagtt tgctggttcg ccaacaggag tgaaatcgaa tttgaagtct
    22621 ccagtcgcta cgatatttcc agaaggtgtt ttcaccacga tccctaatgc atctgggata
    22681 ctatgggtcg ttctgaaaaa gctgacagaa gtctttctaa aacggatgat cgtatcttca
    22741 ttgatctcat ggagctctgc atctcgaagc aagccatgct catctaattt gtttgtgatc
    22801 aacgctaatg cgagaggacc agcatagata ggaatatttg cttgtttcag caagtagggt
    22861 attccgccga tgtggtcttc gtgcccgtga gtaatcacca aggcttttac tttgtgtaag
    22921 ttttgtatga tgtagctgta gtcgggaatg acatagtcaa ttccaagtaa atcgtcttcc
    22981 gggaatttga tcccggcatc aatcaaaatg atttcatctt ggaattgtac cccatacgta
    23041 tttttcccga tttcacctaa tccaccaata gcaaagacgc ctgtctcgtt atttttgatg
    23101 gaaagtttca tattaaaact ccactaatga gaaatcagca ttttcttttt cgtactctag
    23161 atgacttcct tctagaagtt gaacgaattc aatattgtat ggggtatttt cttccacacg
    23221 ttggcgagcg tctacatcgc tttttgcctc aatgtaaaga gattttgttt cttcccgttt
    23281 agggttgcgt acttttgttt cttgataata aactttatag atcattgttt tgtctccttt
    23341 atctgcgtaa agcagtgatt tagctagttg atttttttag acaacacaaa acgaggggac
    23401 aagccacctg gtttttcata tgctttgact agaatactgg attcgagtca aagagacaag
    23461 cctcgttttt gcttatctgt tcggatattt tttcaaccgt accttctgta taaaaaatat
    23521 acaacaatta attgttattc tagcataaaa cagcaaataa gtatagaaat caactagatt
    23581 gaaagaaaaa atcaatgttt atcatcccgc tataatcata atgacttttt tatgagagaa
    23641 gtgttctatt aataggctcg ttgtgctatc atttttagta atgaaaatgt aacaaaagat
    23701 taaaaggaga tgagaaagtg aaactaatgt ggcattatac catgcgttat aagaaattct
    23761 tgtttttcaa tttcatatgc gtatttggtt ttattttgat tgaattagga cttcctacga
    23821 ttttagcacg tatgatcgat gtaggaatcc gcaatgatga ttttgattat gtgaagcaac
    23881 aagggatatt tatgatcgtt attactgtaa tcggtattat tttgaatatc ttgttaggtt
    23941 attttggttc gaggattacg actaatatcg tagcagatat tcgagatgat ttgttcgaaa
    24001 agatccaaag ttattcgcat caggaatacg aaaatctagg cgtatcttca ttgatcactc
    24061 gtacaacaaa cgatgcttat cagatcatgt tgttcctgca aaatatttta cgtatcggtt
    24121 ttatggcacc aatgatgttc attgtcagtt tgtacatggt catgcgtaca agtgtgacac
    24181 tcagtttgta tgtagtaggt gcattacctt tactattatt ggcagtcgta gcgattgcta
    24241 aggtgtctga accgttatct aaaaagcaac aaaaaaactt agataaaatc aacagtatct
    24301 tgcgggaaaa tctttcagga ttgcgtgtga ttcgtgcatt cgtcaatgaa aagtttgaag
    24361 aaaaacgttt tgctgtagtc aatgagaatt atgcttctag ttcaaaaagc ttattccgtt
    24421 tgatggctgt tgcacaaccg ggtttttatt tcttatttaa tatcgtaatg gtattgatca
    24481 tctggagcgg ggcagtgcaa atcgatgcag gcgagcttcg tgtaggagat ttgattgcgt
    24541 ttatcgagta tatattccat gccttgttct cattcatgtt atttgctagt gtgttcatga
    24601 tgtatccaag agcagctgtt tcagctggac gtatccaaga agccctagat gccaaacctt
    24661 cgattgtaga agatccaaat ggtatatctg atacaaaaac taaagggtat atcgaatttc
    24721 aaaatgtaac atttgcttat ccaggccatt cgcaagagcc agtgatacga aatgtcagtt
    24781 ttacagcctc tccaggagag accgttgctt ttattggaag taccggtagc ggaaaatcta
    24841 cgttgatcca attgatccct cgcttttatg atgtgagtga aggaaagatc ttgatcgatg
    24901 gagtagacgt gagagattat cggctaagca agttgcgaga taagattggg tttattccgc
    24961 aaaaagcgct gctatttact ggaacgattg cagataattt gcgatacggg aaagaagatg
    25021 ctacgcaaga agaaatggaa cgtgcagctg agattgctca agcttcagaa ttcatttctc
    25081 gaaaaccaga tggatttaat gaacatttat cagaaggtgg ttccaatttt tcaggtggac
    25141 aaaaacaacg attggcaata gccagagcca tcatacgccg tccggaaatc tatatttttg
    25201 atgacagctt ttctgcatta gattatcaaa cggatgcgaa gttacgtgct cgtctgaaaa
    25261 aagaaacgac agaatctact gtattgatcg tagcacaacg tgtgggaacg atcatgcatg
    25321 cagataagat catcgtatta aatgaaggag aagtcgtcgg tatggggacg catcgggagt
    25381 tgttggaaaa atgcccgatt tattatgata ttgccgcttc tcaattatca aaggaggaat
    25441 tagcatgaaa aaaacctttt cttccttaaa acgtttagct cgatatatca gaccgtatcg
    25501 tgagactttt cttttagtga tcctatttac agttctgaca gtggctttca acgtggcttt
    25561 gccatatgtt acaggacttc ctactacaga aatcagccgt aatattgcca atggcgaatc
    25621 aatcaatttt tcttatatat tcaaatgtct catttggatc acagttgttg gaatagggta
    25681 ttgtatttcg caattacttt ctggtgtttt gatgacaaat gtcgttcaaa gtgccatgca
    25741 tgatttgaga agagacatag aagaaaaaat caatcgtctt ccggtttcat atttcgataa
    25801 aaaccagcaa ggaaatattt tgtctcgtgt gacgaatgat gtagatgcag tcagcggtgc
    25861 tttacaacaa gcttttattg gtatcgtaaa tgcgatattg ggaattacgt tggctgcagc
    25921 aatgatgttt tatatccagc cgatgatggc gctgatctct atgatcatga ttccaacatc
    25981 gatctggatc tcaaaacgag tgatcaatgc ttcgcagaaa tattttcaaa gcatgcagaa
    26041 ttctcttggt gagctaaacg gctacgtcca agaaaatatg acaggtttta gtgtattgaa
    26101 agtatatgga cgcgaaaaag aaacattgga aggattcaaa aaagttaatc acagcttgaa
    26161 atactttggg tttcgtgcag cattcatttc tggcttgatg atgcctctag ttcaattaac
    26221 tgcctatgct acttatattg gtatggctgt tctaggaagc ttttatgtta ttactggggc
    26281 gatcgttgtc ggtcaactac aagcattcat ccaatatatt tggcaaatca gtcagccaat
    26341 ggggaacgtg acacaattgt cttcagtttt gcaaagtgca tcagcggcaa cgaaacgtgt
    26401 attcgagatt ttagatgagc cagaagaaaa agaaaacaaa gtagatgctt cactgccaga
    26461 aacgatttta ggagatgtga cattcgatca tgtcgatttt gcatatgatc cgaagaaacc
    26521 attaatccaa gatttgaatt ttgaagtgaa agctggtcaa accgtagctg tggtcggtcc
    26581 gaccggtgcc ggcaagacga cattgatcaa tctattgatg cgtttttatg acgtagacaa
    26641 aggagcaata aggattgatg gaatcgacac caaatcaatg agtcgcagtg atgtgcgttc
    26701 gctatttggt atggtcttgc aagatgcatg gctttatcaa ggaacgattg cagataatat
    26761 ccgcttcgga aagcttgatg cgacagatta tgaagtagtt gatgctgcga aaacagcaaa
    26821 cgtagatcat tttatccgaa cgatgccaga tggatatgat atggccatca attctgaggg
    26881 agacaatgtg tctttaggac aaaaacagtt gctgacgatt gcccgagcag tggtctccga
    26941 tcctaaaatc ttgattttag atgaagcaac aagttcagta gacacccgtt tagaagcgtt
    27001 gattcaaaaa gcaatggatc gcgtgatgga gggacggaca agtttcgtca tcgctcaccg
    27061 tttatcgaca atccgtgatg cagatctgat tctagtgatg gatcaaggtc agatcattga
    27121 aaaaggaacg catgagagtt tattggcaca aggtggattt tatgaaaaac tgtataacag
    27181 ccaatttgct gaggaagcag aataagtcat ataagaataa aacagtttaa aacttatttt
    27241 ttgttctcta ttcttgataa tggtaaagta aagttatcaa gaaaagtgag gacacggaga
    27301 tggaacagtt tttaaatgaa aaaattactg aagccaaaag agaagttgat cgtttaacgc
    27361 acgtctgtca gacgaagcct tttgattcag ctgatttttt tgaaaatgag tttcaaatcg
    27421 aacgcttggc agcacaaata gaagtgtacg aattaatttt aaaaaaagta atagaagaaa
    27481 atatagatgt acaataaaaa caggtaaaac gtcagttacc agatactgta aatagacatc
    27541 tggcctgagc aggttttacc tgtttttttt cttatgaaat aaatatatgc tatgatacct
    27601 ttattcaata ggattagttt ctacaaaaaa tgaaaggaga aaaataaata tggaacggtt
    27661 tatagcatca aatgccacag tgattggtga tgtgacattg tcagaagatg tgacgatctg
    27721 gtatcaagct gttttacgcg gggacagtaa ttggataaaa ataggacaaa gaacgaatat
    27781 ccaagatggt acaatcatcc atgtcgatca tgatgcacct gtagatattg cggagaatgt
    27841 gacggtagga catcagtgca tgctacatgg ctgtacaatc gaaaaagggg cgctgatcgg
    27901 gatggggacc acgatattga atcatgcggt tattggtgag aatagtttga ttggtgctgg
    27961 atcattagta acagaaggaa aagttattcc tcctaatgtc ttggcttttg gtcgcccagc
    28021 taaagtgatc cgtcctttga caaaagaaga aatacaaaaa aacaaagaaa acatccagca
    28081 ttatgtcgag ataggtcgga tgcatgcgca aggaaaattc aaggagcaaa gataggcagt
    28141 agcatccata aaataaaaaa ggatggtcag tttgagttga ccatcctttt ttatttggtt
    28201 tagataagag agcttaaaaa agcttccttt gaaacagatt aatttaatga agaactgttt
    28261 tccatgactt catcgatcaa tccatatgct tttgcttgtt cagctgtcat atagttgtca
    28321 cgatctgtat ctttttcaat cacttcaagc ggttgtccag tgcgttcagc taaaattttg
    28381 tttaagcgtt cgcgtgtttg caaaatatgg cgtgccgcaa tttcgatttc agttgcttgc
    28441 ccttgagcgc cgccaagagg ttgatggatc atgatctcag catttggtaa agcaaatcgt
    28501 ttaccttttg taccagctgt cagcaagaag cttcccattg aagcagccat acccataaca
    28561 attgtttgga catctgcttt gacaaagttc attgtgtcgt aaatagccat acctgctgta
    28621 actgaaccac caggagaatt gatataaaga tagatatctt tttcagaatc ttgagcgtct
    28681 aagaaaagca attgggcgat gatcgaatta gcaagatcat ctgttacttg gccgcttaac
    28741 atgatgatac ggtctttcaa taaacgtgag tagatatcgt aagctctttc acctcgtgaa
    28801 gattgttcaa tgactgtagg aattaaattc ataatagagt tcctccttga tttcgtttag
    28861 aaatagtgta ccataattta gtttctaata cctaaaatgt agtatacatt tttggtcaaa
    28921 aaaggtcaaa taaaaaactt aggcaaatta gtcgcataaa cccgctttat ggtatgataa
    28981 gcagagaaac aaaacaagga ggaacaacag attgatagtt ggtattactg gccttatcgg
    29041 agtgctgaca ggtgctgtag ttgtctatat cggcatgata ctgcaaatgc gtcacttgga
    29101 aaataaagaa cagcgtagac gtgaattgga attgaaagtc aaagaaatcg agacgctgaa
    29161 tcaattaaat aaaaagatca acgagatctt gcaaaaacgg acaacgctga tggaagaata
    29221 tgtcagcttt gatgcatttg atgattgtta tatcacgatt gacgattttg cgtatctcca
    29281 atcattttca gcgcaaaata gtttttatct gccaaattat attttagacg agctatttaa
    29341 gaatatctcc catcgaaaag tgattttatc tccagatgaa acaatgaaga ttggtggata
    29401 tgcttataaa ggcggacgcg tgattttaga gaattttacg gatagtctga ctgaaatgat
    29461 caatgaaaaa aaagctcagt tgaagactat gacgcgccag ccgattggtt tcttctcgaa
    29521 agatgatgtt tggagctgat attttgaagc attgccgttg cacatgagag cgtggtaatg
    29581 ctttcttttt ttcttaatga tacaatagaa ctgaacggag tgaagaaaga tgttacaaat
    29641 ctatgcccat cgcggaagca gcggcaccca cccagaaaat acgcttcctg catttgcaga
    29701 agctgtacga gtaggtgcag atggtatcga actagatgtc catctaagca aagatggtta
    29761 tttgatcgtt atgcacgacg aagaagtgga ccggacgact aacggtaaag ggctgattcg
    29821 agaaaaaaca ttggaagaac tcaaaaaatt gaatgcaggg ggcaaattca gcaaagaatt
    29881 tccagcagct aaagttcctg aattgagaga agtgttagga ctgctcctcc aaaaaaatta
    29941 ccgagggatg ctaatgattg aaattaaaac tgatcagtat gaatatcccg gtatcgaaga
    30001 aaaattagcc gaaacattaa aaagtagaga ttggcctttt caacatgcat attgcagctt
    30061 tcatttggat tctttggaaa aaatcgcatt actggaaccg gagatacagc tggacttatt
    30121 gatgagtact tctgataaaa agatccaact agcagcagaa accccttata tagaaggagt
    30181 acatccaaaa aatacttggt tgttcgaaca tccagtccag gcagctgatt ttccaaaagc
    30241 aattcgtgca tggacgatta acgatgaaga agaaatggcc aaatgtcaag aactcaaaat
    30301 agatggaata ataactgatt ttccggagaa agctcttcgg tggaaacaat caacgaaaag
    30361 taggtaaaat atggaaaaag tattagtgat cgtcggtccg acagcagtcg gtaaaacagc
    30421 gctaagtgtg gaactcgcac aactatttgg aggagagatc atcagtggtg attcattgca
    30481 aatctataaa aatctggata tcggtacagc aaaaatcaaa gaagaagaga tgaataatgt
    30541 tccgcatcat ttgattgatg tgatcgaacc tactcaacgt tactcagccg ctgattttca
    30601 gcattcaggt cgacaattga ttaccgagat tgcgaaccga gggcacctac ctatcatagc
    30661 tggtggtacg ggtctctata tccaatccct tctatatgat tatcagttag gagcgacaga
    30721 agaagcgaat cctgagatta gaaaaaagta tgaaacgtta gctgaaacaa ttggttccca
    30781 agcattatgg aatcagttga aagaaaaaga cccggcagct gctgagaaaa tccactggaa
    30841 caatcaacgc aaagtgataa gagctctgga agttttagag acgacaggac atagtatcac
    30901 ggcacctaaa gaagagccaa agcaattgta tgattacctc atgattggat tagatacgaa
    30961 gcgtagtatt ctttatgaac gaatcaatca aagagtcgat ttgatgctag cagaaggttt
    31021 agtagcagaa gcgcgtaagg tgtatgagct tggagaagtc caggccagtc aaggtattgg
    31081 atataaagaa tttttccctt attttgaagg gaaagaaaca ttggaagaag caacagaaca
    31141 agtcaaacta cattcgagaa gatacgcgaa acgtcagttg acgtggtttc gtaaccgttt
    31201 ggatgcacag tggtttgatc ttataagtga gccaaatcaa aaaagtcaga ttgagcaaac
    31261 aatcaaaaaa tggctggagg cggaataaaa tggaagaaaa agtgatcatc gtaggggtag
    31321 aaaccgaagc aaaccagcgt tacttttcag agtcaatgga agagctagtt cagctgacga
    31381 ataccgcatc aggagaagtc gtattcacaa ttacacaaaa gagaccacaa gtggatcggc
    31441 aaacgattat cggtaaaggg aaattacaag aattagttca acaagcggat gcgcatgaag
    31501 cggatttgat catctttaat catgagctaa ctccgagaca gagccaactg attaccgatg
    31561 ctgttggtct tccggtaatt gatcgcgtgc agcttatctt agatattttt gcgatgcgtg
    31621 ctcgttcgaa agaagggaag ctgcaggttg aacttgctca gttagaatac ctgctgcctc
    31681 gtttagtagg gcaagggaaa acattatctc gtcttggcgg tgggatcgga acaagagggc
    31741 caggtgaaac aaagttagaa acagaccgcc gacatatacg gaataaaatt tttgctgtta
    31801 agaaagaatt gaaagaagta gaagctcatc gagagcgcaa tcgccaaaaa agaaaaaata
    31861 gcgagatttt tcagattgga cttattggct acacgaatgc cgggaagtca actatcttga
    31921 atctattgac acaagcggat acttattcga aagatcaatt gtttgcaacg ttagatccat
    31981 tgactaagag atggcgtttt gctgaaggat ttgagattac tgtaacggat accgtcgggt
    32041 tcatccaaga cctgcctacg caactgatcg atgctttcca ttctacatta gaagaaagtc
    32101 aaaatatgga tcttttgcta catgtagtcg atgctagttc tccagatcgt attttacagg
    32161 agcagactgt cttaaaattg atggatgaac tgaatatgaa agaaatgccg atactgactg
    32221 tttacaataa ggcagaccag atcgacccag cgatgttcac gcctacgcta ttcccaaatg
    32281 tattgatttc tactcagacg aaagaaggta agatggcgtt gatcgaagca atcaaacgtc
    32341 agctgatgga actaatgacc ccttatacac tttctgtgcc aagcaacgaa ggacagaaat
    32401 taagcgagtt gagaagacaa acaatggttt tggacgaagc gtacatggaa gaaacaaacg
    32461 aatatgaagt taaagggttt gcaaaaacca attcaaaatg gttaagaaaa aaccaataaa
    32521 attttatttt tttaa
//
LOCUS       DAPBBV010000032        31115 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.032, whole genome shotgun sequence.
ACCESSION   DAPBBV010000032 DAPBBV010000000
VERSION     DAPBBV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31115
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.032"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            23..646
                     /locus_tag="RD486_001853"
     CDS             23..646
                     /locus_tag="RD486_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663581.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="RD486_001854"
     CDS             1096..2145
                     /locus_tag="RD486_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7663582.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="RD486_001855"
     CDS             2142..3023
                     /locus_tag="RD486_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663583.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="RD486_001856"
     CDS             3026..3796
                     /locus_tag="RD486_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7663584.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="RD486_001857"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="RD486_001857"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDT7663585.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="RD486_001858"
     CDS             5107..6270
                     /locus_tag="RD486_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7663586.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVES
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="RD486_001859"
     CDS             6387..6797
                     /locus_tag="RD486_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7663587.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="RD486_001860"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="RD486_001860"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7663588.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="RD486_001861"
     CDS             9370..9654
                     /locus_tag="RD486_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663589.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="RD486_001862"
     CDS             9814..10050
                     /locus_tag="RD486_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7663590.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="RD486_001863"
     CDS             10047..10445
                     /locus_tag="RD486_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HDT7663591.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="RD486_001864"
     CDS             complement(11112..12056)
                     /locus_tag="RD486_001864"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDT7663592.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="RD486_001865"
     CDS             complement(12352..13296)
                     /locus_tag="RD486_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663593.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="RD486_001866"
     CDS             13517..14731
                     /locus_tag="RD486_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7663594.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="RD486_001867"
     CDS             14753..16768
                     /locus_tag="RD486_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HDT7663595.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="RD486_001868"
     CDS             complement(16851..18224)
                     /locus_tag="RD486_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDT7663596.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="RD486_001869"
     CDS             complement(18250..18534)
                     /locus_tag="RD486_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7663597.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="RD486_001870"
     CDS             complement(18536..20551)
                     /locus_tag="RD486_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7663598.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="RD486_001871"
     CDS             complement(20730..21035)
                     /locus_tag="RD486_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HDT7663599.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="RD486_001872"
     CDS             complement(21124..22155)
                     /locus_tag="RD486_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7663600.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="RD486_001873"
     CDS             22362..23237
                     /locus_tag="RD486_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7663601.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="RD486_001874"
     CDS             complement(23389..24231)
                     /locus_tag="RD486_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7663602.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="RD486_001875"
     CDS             complement(24323..26200)
                     /locus_tag="RD486_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7663603.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="RD486_001876"
     CDS             complement(26197..27618)
                     /locus_tag="RD486_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7663604.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="RD486_001877"
     CDS             complement(27621..31010)
                     /locus_tag="RD486_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDT7663605.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
BASE COUNT         9553 a         5658 c         5991 g         9913 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaagt
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattatattt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactagat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca tttgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa ttcggatcaa
    24961 ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg tcgatttctt
    25021 tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca aatgttaaag
    25081 cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt ccttctttat
    25141 cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca tttttgatgg
    25261 tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt gtttgctttt
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacttcta
    25381 aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag atccttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt atttgttgta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attat
//
LOCUS       DAPBBV010000033        29948 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.033, whole genome shotgun sequence.
ACCESSION   DAPBBV010000033 DAPBBV010000000
VERSION     DAPBBV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.033"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(26..328)
                     /locus_tag="RD486_001878"
     CDS             complement(26..328)
                     /locus_tag="RD486_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7663606.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="RD486_001879"
     CDS             complement(353..2446)
                     /locus_tag="RD486_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7663607.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="RD486_001880"
     CDS             complement(2935..3699)
                     /locus_tag="RD486_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HDT7663608.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="RD486_001881"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="RD486_001881"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HDT7663609.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="RD486_001882"
     CDS             complement(4704..5780)
                     /locus_tag="RD486_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HDT7663610.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="RD486_001883"
     CDS             complement(5804..6397)
                     /locus_tag="RD486_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HDT7663611.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="RD486_001884"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="RD486_001884"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HDT7663612.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="RD486_001885"
     CDS             complement(8067..8366)
                     /locus_tag="RD486_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HDT7663613.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="RD486_001886"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="RD486_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HDT7663614.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="RD486_001887"
     CDS             complement(10121..11032)
                     /locus_tag="RD486_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDT7663615.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="RD486_001888"
     CDS             11152..12009
                     /locus_tag="RD486_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7663616.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="RD486_001889"
     CDS             complement(12196..12558)
                     /locus_tag="RD486_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDT7663617.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            12904..14343
                     /locus_tag="RD486_001890"
     CDS             12904..14343
                     /locus_tag="RD486_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663618.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14350..16902)
                     /locus_tag="RD486_001891"
     CDS             complement(14350..16902)
                     /locus_tag="RD486_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDT7663619.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17016..18347)
                     /locus_tag="RD486_001892"
     CDS             complement(17016..18347)
                     /locus_tag="RD486_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7663620.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18313..19791)
                     /locus_tag="RD486_001893"
     CDS             complement(18313..19791)
                     /locus_tag="RD486_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7663621.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="RD486_001894"
     CDS             complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="RD486_001894"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HDT7663622.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22401..23828
                     /locus_tag="RD486_001895"
     CDS             22401..23828
                     /locus_tag="RD486_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663623.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23920..24285)
                     /locus_tag="RD486_001896"
     CDS             complement(23920..24285)
                     /locus_tag="RD486_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HDT7663624.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24282..24647)
                     /locus_tag="RD486_001897"
     CDS             complement(24282..24647)
                     /locus_tag="RD486_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HDT7663625.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24839..25087)
                     /locus_tag="RD486_001898"
     CDS             complement(24839..25087)
                     /locus_tag="RD486_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663626.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25086..25214
                     /locus_tag="RD486_001899"
     CDS             25086..25214
                     /locus_tag="RD486_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HDT7663627.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25271..26965
                     /locus_tag="RD486_001900"
     CDS             25271..26965
                     /locus_tag="RD486_001900"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HDT7663628.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            26969..27088
                     /locus_tag="RD486_001901"
                     /pseudo
     CDS             26969..27088
                     /locus_tag="RD486_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            27616..28749
                     /locus_tag="RD486_001902"
     CDS             27616..28749
                     /locus_tag="RD486_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HDT7663629.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28780..29100
                     /locus_tag="RD486_001903"
     CDS             28780..29100
                     /locus_tag="RD486_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HDT7663630.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29129..29593)
                     /locus_tag="RD486_001904"
     CDS             complement(29129..29593)
                     /locus_tag="RD486_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7663631.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29725..>29948)
                     /locus_tag="RD486_001905"
     CDS             complement(29725..>29948)
                     /locus_tag="RD486_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7663632.1"
                     /translation="VSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAA
                     VNLVLSILIYLPFVKVATIQERRKEALDA"
BASE COUNT         9032 a         6212 c         5170 g         9534 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
    14341 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
    14401 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
    14461 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
    14521 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
    14581 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
    14641 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
    14701 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
    14761 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
    14821 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
    14881 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
    14941 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
    15001 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
    15061 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
    15121 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    15181 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
    15241 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
    15301 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
    15361 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
    15421 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
    15481 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
    15541 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
    15601 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
    15661 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
    15721 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
    15781 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
    15841 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
    15901 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    15961 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
    16021 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
    16081 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
    16141 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
    16201 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
    16261 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    16321 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
    16381 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
    16441 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
    16501 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
    16561 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
    16621 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
    16681 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    16741 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
    16801 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
    16861 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    16921 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    16981 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
    17041 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    17101 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    17161 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    17221 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    17281 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
    17341 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    17401 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    17461 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
    17521 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    17581 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
    17641 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
    17701 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
    17761 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
    17821 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    17881 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    17941 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    18001 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    18061 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    18121 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
    18181 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    18241 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    18301 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    18361 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    18421 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    18481 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    18541 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    18601 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    18661 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    18721 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    18781 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    18841 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    18901 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    18961 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    19021 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    19081 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
    19141 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    19201 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    19261 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    19321 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    19381 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    19441 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
    19501 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    19561 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
    19621 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    19681 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    19741 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    19801 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    19861 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    19921 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    19981 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    20041 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    20101 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
    20161 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    20221 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    20281 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    20341 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    20401 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    20461 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    20521 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    20581 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    20641 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    20701 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    20761 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    20821 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    20881 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    20941 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    21001 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    21061 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
    21121 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    21181 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    21241 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    21301 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    21361 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
    21421 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
    21481 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    21541 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    21601 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    21661 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    21721 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    21781 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    21841 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    21901 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    21961 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    22021 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
    22081 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
    22141 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
    22201 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
    22261 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
    22321 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
    22381 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
    22441 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
    22501 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
    22561 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
    22621 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
    22681 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
    22741 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
    22801 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
    22861 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
    22921 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
    22981 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
    23041 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
    23101 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
    23161 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
    23221 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
    23281 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
    23341 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
    23401 tttatctttt aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
    23461 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
    23521 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
    23581 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
    23641 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
    23701 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
    23761 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
    23821 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
    23881 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
    23941 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
    24001 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
    24061 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
    24121 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
    24181 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
    24241 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
    24301 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
    24361 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
    24421 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
    24481 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
    24541 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
    24601 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
    24661 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
    24721 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
    24781 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
    24841 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
    24901 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    24961 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    25021 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    25081 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    25141 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    25201 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
    25261 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
    25321 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    25381 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    25441 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    25501 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    25561 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    25621 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    25681 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    25741 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    25801 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    25861 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    25921 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    25981 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    26041 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
    26101 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    26161 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    26221 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    26281 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    26341 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    26401 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctattgt
    26461 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
    26521 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    26581 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
    26641 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
    26701 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
    26761 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    26821 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    26881 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    26941 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
    27001 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    27061 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaagctg ccctgcatca
    27121 agtaataaga gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt
    27181 accgcagatg caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt
    27241 tcgagtatga agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt
    27301 aataccgaga aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt
    27361 gaaaacaact attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac
    27421 aactatttca atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa
    27481 tacataagac tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa
    27541 gatctccttt aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg
    27601 aaaggagcat ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga
    27661 aacgtagatg atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca
    27721 gccatttgcg gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg
    27781 tatgttgtag gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca
    27841 ttgaaaaaag ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc
    27901 tgcctgaatc acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg
    27961 cttttcggat ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga
    28021 gttccttatg cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa
    28081 gttttatttc tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta
    28141 aaaaaaggcg atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa
    28201 ttcgctgtta tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta
    28261 gataaagcgg ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct
    28321 ggaacagaat tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga
    28381 atggacggat tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc
    28441 acaatctctc cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta
    28501 actggtgttt atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat
    28561 atcgctgtca agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg
    28621 attgcagaag gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa
    28681 gcagcacaag catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg
    28741 aaaccttgaa ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat
    28801 acccatgaga tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc
    28861 ttctatttcc aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt
    28921 ttctatattt ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat
    28981 ttttatttgg ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac
    29041 atttttattt acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga
    29101 gaatttttca aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag
    29161 cggtcgtccc actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa
    29221 acgtggtatg atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc
    29281 tgatttccgc taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca
    29341 gggcacaaag atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg
    29401 ctcctccgac gatggtttct ttttcatcta agaccacata ccattgagga atactttcct
    29461 tattagcgat tccagtacga atactttcct catacacaac agcaggaact ccccattttg
    29521 atgaaaacca attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt
    29581 tatatgtaac caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag
    29641 tctttatgaa aattagcaat gacaacaata gtgatgtaaa aaaaaaaacg gaaaacaatc
    29701 acttgttctc cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat
    29761 cgtagctacc ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc
    29821 tagtacacca cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac
    29881 ccatggaggc ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac
    29941 actaacta
//
LOCUS       DAPBBV010000034        29218 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.034, whole genome shotgun sequence.
ACCESSION   DAPBBV010000034 DAPBBV010000000
VERSION     DAPBBV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.034"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..1813)
                     /locus_tag="RD486_001906"
     CDS             complement(<1..1813)
                     /locus_tag="RD486_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDT7663633.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEG"
     gene            complement(1826..2101)
                     /locus_tag="RD486_001907"
     CDS             complement(1826..2101)
                     /locus_tag="RD486_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663634.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(2463..2918)
                     /locus_tag="RD486_001908"
     CDS             complement(2463..2918)
                     /locus_tag="RD486_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663635.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(3072..4280)
                     /locus_tag="RD486_001909"
     CDS             complement(3072..4280)
                     /locus_tag="RD486_001909"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDT7663636.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(4392..4724)
                     /locus_tag="RD486_001910"
     CDS             complement(4392..4724)
                     /locus_tag="RD486_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDT7663637.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            4872..5747
                     /locus_tag="RD486_001911"
     CDS             4872..5747
                     /locus_tag="RD486_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7663638.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(5829..6410)
                     /locus_tag="RD486_001912"
     CDS             complement(5829..6410)
                     /locus_tag="RD486_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HDT7663639.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(6416..7675)
                     /locus_tag="RD486_001913"
     CDS             complement(6416..7675)
                     /locus_tag="RD486_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDT7663640.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(7677..8723)
                     /locus_tag="RD486_001914"
     CDS             complement(7677..8723)
                     /locus_tag="RD486_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663641.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(8958..9233)
                     /locus_tag="RD486_001915"
     CDS             complement(8958..9233)
                     /locus_tag="RD486_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDT7663642.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(9476..10786)
                     /gene="der"
                     /locus_tag="RD486_001916"
     CDS             complement(9476..10786)
                     /gene="der"
                     /locus_tag="RD486_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDT7663643.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(10968..12197)
                     /gene="rpsA"
                     /locus_tag="RD486_001917"
     CDS             complement(10968..12197)
                     /gene="rpsA"
                     /locus_tag="RD486_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDT7663644.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(12332..13012)
                     /locus_tag="RD486_001918"
     CDS             complement(12332..13012)
                     /locus_tag="RD486_001918"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDT7663645.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(13061..13696)
                     /locus_tag="RD486_001919"
     CDS             complement(13061..13696)
                     /locus_tag="RD486_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7663646.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(13762..15165)
                     /locus_tag="RD486_001920"
     CDS             complement(13762..15165)
                     /locus_tag="RD486_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDT7663647.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(15152..16183)
                     /locus_tag="RD486_001921"
     CDS             complement(15152..16183)
                     /locus_tag="RD486_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663648.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            16214..16435
                     /locus_tag="RD486_001922"
     CDS             16214..16435
                     /locus_tag="RD486_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDT7663649.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(16600..17337)
                     /locus_tag="RD486_001923"
     CDS             complement(16600..17337)
                     /locus_tag="RD486_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HDT7663650.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(17490..18830)
                     /locus_tag="RD486_001924"
     CDS             complement(17490..18830)
                     /locus_tag="RD486_001924"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDT7663651.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(19067..20590)
                     /locus_tag="RD486_001925"
     CDS             complement(19067..20590)
                     /locus_tag="RD486_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDT7663652.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(20969..21580)
                     /locus_tag="RD486_001926"
     CDS             complement(20969..21580)
                     /locus_tag="RD486_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7663653.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(21703..21828)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(21910..22626)
                     /locus_tag="RD486_001927"
     CDS             complement(21910..22626)
                     /locus_tag="RD486_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDT7663654.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(22632..23201)
                     /gene="scpB"
                     /locus_tag="RD486_001928"
     CDS             complement(22632..23201)
                     /gene="scpB"
                     /locus_tag="RD486_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDT7663655.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(23185..23982)
                     /locus_tag="RD486_001929"
     CDS             complement(23185..23982)
                     /locus_tag="RD486_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDT7663656.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(23952..24323)
                     /locus_tag="RD486_001930"
     CDS             complement(23952..24323)
                     /locus_tag="RD486_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDT7663657.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(24342..25229)
                     /gene="xerD"
                     /locus_tag="RD486_001931"
     CDS             complement(24342..25229)
                     /gene="xerD"
                     /locus_tag="RD486_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDT7663658.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(25325..25798)
                     /locus_tag="RD486_001932"
     CDS             complement(25325..25798)
                     /locus_tag="RD486_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7663659.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(25903..26766)
                     /locus_tag="RD486_001933"
     CDS             complement(25903..26766)
                     /locus_tag="RD486_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDT7663660.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(26962..29061)
                     /locus_tag="RD486_001934"
     CDS             complement(26962..29061)
                     /locus_tag="RD486_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDT7663661.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT         8120 a         6213 c         4914 g         9971 t
ORIGIN      
        1 ttccttcaag tttgcgttgc tggataaaaa attgaaccat cgtttcatca taaatatcag
       61 tcaagttatc taaactttca ataatcaact gagtattttt ttgatatgtc tctctgattt
      121 cttggatatc ttcatcacta ataaatgtct gacgatcagc atatcttctt tgccaaaaca
      181 ttttcggatg gagaacgatt cgcattaacc tacggacaac aatgaaccaa aagccgataa
      241 aagacaaaat ctggcttgtg atagaatgtt cgaatcgaga aagaaaacgg gagtaaaaac
      301 gataaccatt agaagaaagc ttgcccgaac gataactttc atccaatcca tcccgttcga
      361 tcgacaaaat cagtgcttgt atttcttgta cttcttgctt ttcatcatcg gttaaatctt
      421 ccaagtacag atcacgtatc cgttcttgat aattttctat cactgcttca gtggctaaaa
      481 attcttttgt attacgatca atttccttta tttcttttcg caaaacttca acgacctctt
      541 ctaaaatcat caaagcattc aaatccgtgc ttttcgcttc ctctgtttcc gtcagcatag
      601 gcaagacaat gatccctatg accaaagtca ctaagatgac acccgccgtc agaaacaaaa
      661 gcaaagaccg ctggtaaaac atcatattat tgattgaaaa tggcaaaata aaaatcgtag
      721 ccaaactgac tgttcccttt acaccgccaa atgttaagat caagatctcg ttcaactgtt
      781 ttttgaactt tttactgcca tctttgaata cataaaaaag actgatagaa atgaatctga
      841 tcacaaaaag catgacagag attaatacga taatcgctaa taaaagaccg tttggatata
      901 aaccgtctcc ccatactggc gagaacactt gcgtcaattc gattcctaaa aatataaata
      961 ctaatgcatt cagtgtaaaa gcaatagttg tccatgtact gtgggacaag ctcgacaatt
     1021 ctgcatcaaa cacagagatt ttcctaaaac cagaagcttg gagaatacct gctgccactg
     1081 cagcaatgat tccagataca tcaaatgcct ctgccaatac ataggctaga aaaggaagca
     1141 aaagttcgat cagcagatac cctgtgacat cttgtgctga tgctttttcg atcaaatgaa
     1201 ttattttttg tttgaaccag acaagcaaaa agccgatcaa agctccccca atactagaaa
     1261 ctactagact catccccgcg tttactgctg aaaaagatcc ggtgatcagc gcaccaagag
     1321 caaactggaa ggcagtaaca ccagatgcat cattcaaaag accttctcct tccaaaatat
     1381 gcatcgcctt tttagggata ttcactcgtc cagaaagaga actgactgct accgcatctg
     1441 tcggacctaa cgctgctcca aaagcaaagc aggcagcaag tgggacactt ggcaacagga
     1501 atgataacgt cgcacctacc ccgacaaggg tcaaaatgac tcctccaaat gccaagaaca
     1561 aaattgtccc gaaatttttg agaatcgaag aaatatctgc tttttctcct tctctaaata
     1621 acaatggtgc aataatcata actaagaaca attcaggttc aaaatcgatt gattgtcccc
     1681 actctgtcag acctaatacc actccaagga aaatttggat cagtggagct ggaatcattg
     1741 gcaaaatgcg gctagctatg ttcgataagg tgatcgttac tgcaaataca ataactaact
     1801 cagcaaattc catcgtccat cccctttatt ttttattttg tgtaagcatt tttaaaaatt
     1861 gttctttttt ctttaaaatt ttggtttcga ctacttcaac ctgtgtttgg ttcccctcta
     1921 attcacactg tacacgtttt gactccaaac gaagcagatc atgtttcaga cgttccaact
     1981 gacgatacat caatatattt cttttacgca acttacaaag tatttgacgg cggtcatcca
     2041 tcgaaagggc gccatagcga tcatgcaaca gttttttttg ttgttcaaaa ctctctctca
     2101 ttttccagat ctcctataca caaacttcca tcattatagc aaagttcttt ttggatgaaa
     2161 aatatttcat tgtttcatcg tttattgcta gttagaaatt tccataaatt tttcaacgcc
     2221 tcattctatt ccaaatagta tcagatatca agtaaaactt aagaaagata aaagtttctg
     2281 acaaaaggat gtttactttc ccattcctgc ctttcttgtt cttttatcac aacaaaaaaa
     2341 tggggctgcg acaaaaatct tgtcacagtc ccttattctg aataaacggt gtggaagaga
     2401 cagcctatca gtagtaataa gacacatctc tttcacagcc tcatttttgc gtaaaaatcg
     2461 atttattcga aaaattcccc gtatacatct tctacacgtt gatctggatt gatcacgata
     2521 tacaagttac ctgttttttc gctgattttt gttgattgat attgattgtc taatccttct
     2581 gttcctttat ctagatatgg gaagtacaca agatcaggtg tgccatttcg gtaaaggatt
     2641 tccattcgct cgatatcttc gtatttcaat gcgcgattaa acatgcccat ttccagtccg
     2701 cctaggttga tatcatgtgt cgcaactgcg tccccttcat ggaagatttc gattttaaat
     2761 ccagcacacg gatggatttc aacaaattca ctgccattga ttcgtccaaa acttgttgtg
     2821 atttgtttga tccaaagatc gccgatatga cggcggttga tcgtccaggt ttctccattt
     2881 ctaaaataaa attttagcgc tgtcatttct ttactcatta aaaagactcc tttatgatgt
     2941 aatttattct tgtactacct cagtttagca caaatttatg taagtggtca catcttatgt
     3001 tttttcttct aatgacgtat ctgcccactt taagtagcca acaaagctga gcagatacag
     3061 tctagtgttt tttaaatcaa tttttctttc gataaaaaat ccaaaacctg ttttttatca
     3121 ttttttattc tttgttctac gacggctttt tcagctaatt gcaaagcttc actaacccac
     3181 ttaccaggtt tttttccagt ttcttctagc aagattttac catctactgc taattcgctt
     3241 aatgacttga taggtaaacg atcataggat tctcctacgg catccatctg aggtgtttcg
     3301 tcaaaataga tcatcaattc ttctacttgc agtgcatgtt ttttgcctaa gaagtacaat
     3361 tcgaatggtt ccaaagctcc agtttctcgt tgtcgtagtc cttggacaag tgcttgaacg
     3421 tctttaatca tttggttaga acacttccac gatttcaaaa aggaacgaat ctcattttct
     3481 tttagatcca gttggctgat caataatgcc catgcttggc tctcttcttt caatgggacg
     3541 gatggtaatt cagcaaaacg taaaagtgct tcgccttctt ctttcaaacc gggacagcaa
     3601 atgtagcact ctgtttcaat aaatgcatgg attcccgcgg cccgttcatt tcccaagagc
     3661 atcttgatga attccacatt tatacgttct acagatattt tacctaatag ctcgtggttt
     3721 tctttgatgg cgtagaaggt ttcttcctct aatttgaacc ctagttgact gacaaaacgc
     3781 aacccgcgca tcattcgtaa ggcatcttca tggaaccgct catgaggatt gcctacagct
     3841 cgcaagatct gttcttctag atcttgcaga ccatcgaaca aatcgatgat ttctccatct
     3901 tctttcaaag caaacgcatt gatcgtaaaa tctcttcttt tcaaatcttc tgccaacgaa
     3961 cgaacgaatt cgacatgatc tggtctacgg tagtcctgat aagttgattc cgtccgaaat
     4021 gtggtgatct catattgttc atcattttct aataccaaca cagttccatg ttcgatccca
     4081 atatctatcg tttttggaaa aagctgtttg atttcttctg gaaatgcgct tgttgcgata
     4141 tccacatcat ggattggctg gttcagcaag atatcacgaa cacttccacc tacaaaataa
     4201 gcttcatatc ctgcattctc taattttttc agaactggaa ttgccttttg gtattccaga
     4261 ggtaattgtt ttaatttcat ttttccaacc tttcctgcgt gtttcttgtc ctgagataaa
     4321 gactcagttg catggtgact gtttgacaag tccgtttcag agtcttcaag gccaggacca
     4381 cttcatcttg tttactcgtc cttacgctca aagcgattat ggtctctttg attgaatttt
     4441 tccatgtttt tttcaaaaac ttcagttaag tcgatattca atgaattagc catgatcatc
     4501 gtaacgaata aaacatcacc aagttcttct gctaccgagt taactggttc agaagccttt
     4561 ttgctttttt ctccataagt gtggttgact tctcttgcca attcacctac ttcttcagtt
     4621 aatcgagcca tctgagctaa tggagagaaa taccccacct tgaattgctg gatatattca
     4681 tccacttcct gctgcatact gtataaagaa cgctttttat ccatcttttt ccctccaaaa
     4741 ctatcttacc aaaactttaa cgcaaatcct agataagagc aattgagaaa atcgaatttc
     4801 catgctacat ttaggaagga atttctaaat ggaaattctg tgaaaataca taattgaaag
     4861 ctggaattca tatggtcaaa cgaaaaacag taaaagaagt tctttttatc attataggaa
     4921 caagtattta tgcatttggt cttgtttact tgaacatcgc taatcattta gcagaagggg
     4981 gagtctcagg gatcaccttg atcttaagag ctttatttgg tattgatcca gcttatacga
     5041 ctttattaat caacatccca ttgattttac taggaggaaa gatcctcggt aaacgttcct
     5101 tggcctatac tgttctaggt acactttctt tgtcattctt tttatggatc tggcaaaggg
     5161 ttccactaga aatcaattta cagcatgatc tactgatcgt ttctctactt gcgggtttag
     5221 ttgcaggtgt aggaagcggg atcgtctacc gcatgggtgg aacaacaggc ggcagtgata
     5281 ttatcgctcg gattttagaa caaaattacg gcatcactat ggggcgttcc ctattggcat
     5341 ttgatatcat cgtcttactt gcttcattaa cctatatcga cttgaaacgt atgatgtata
     5401 cgttgattgt ttcgtatgtt ttcagtcgtg tgattgattc gatcttagat ggcggatatt
     5461 ctgcaaaagg tctacttgtc gtctccaaca aaagcgaaga gattgcacca ctactgatga
     5521 ccggtctgca aagaggtgtg actttccttt ctggagaagg cgcattctct ggtaattcaa
     5581 aaaaaatcat ctatatggtc gttagctcta gtgaattaac tgaagctaag aggatcgtcc
     5641 acgagattga cgaaaaagct ttcctttcaa tcatcaatgt gcatgaagtg gaagggcaag
     5701 gctttactta tttgaagcca cagacaagat tactgaaaaa actataagaa aaaagacaaa
     5761 gataggctat gaggaaagat tccacatcca gctgaccttt gtctttttta gtactatact
     5821 atttttaact aattgttatg ttcacttacc cggttacttt tcttttgtgt ctgcaaaagg
     5881 atctttcggt taacttcatc agataatttc aaaaaagcat ccctatctcc atcttctagt
     5941 gcttgatcga tttgagcata aagcattttt agttttgcct cttcttcttt ttcttgaaaa
     6001 tatcgttcaa ttaattcagt atcttcttca ctgactgaag aatcccaaga agaaaatgga
     6061 ttgtcttcta agatagatag atattctctt gtctgccaag cattttcgaa tatacattcc
     6121 acatataaag gctttttcca attcaaacgg atttcatgaa aaatctggtc tgtgtccgta
     6181 aattcttttc cctgcaaaaa caatttcatg ggttcccctt caacagatag atcactgatc
     6241 tgcagtcctc gatccgcaaa attcgcccct tcaacaaagt ggacattgct taaaatcgct
     6301 tcatgattgg caagataatt caagatccaa aaaacttctc ttcggctaaa agatacatga
     6361 ttgaccatcc acgttaaaaa attcttcttt tcccgtacat caattagcat ttttctcacc
     6421 tctctgttag gtcatctaat aatgacagtg cctccatatc tcctggttca agtgttaaat
     6481 aataagtcaa taattcttgc gctcttttca gctgcccttc ttctcttaag aaaaaggcat
     6541 actctttcaa gaaatctggt tcatgtgata gttcatgata agcctgttca tagtgtacag
     6601 ctgcaacggt aaagtcttct aattcattat aagcatgggc taggttccat tctgcataag
     6661 gattagcagt ttcttccatc tgattgatca cttgtatcac atcttcatat ctttcatcat
     6721 ccaagtaaag attacttaaa gtaagtaatg tttcatcttg tttgtctcct acttctaaag
     6781 ctttcagtaa aagttcttct gctcgctgtc tatcatgcag acggaaagca ttttccgagg
     6841 ccaggtgata aagttcgact tggtaaggat tttctttgat tccttcttct aacactgttt
     6901 gtgcttcttc aatcatttct tcttcttgaa gagcttgtcc tagatataga tataacgatt
     6961 gataatgcgg attaacttct cgaagttctt ccagatagtt gattgcctgc tgattttctt
     7021 tcaattgaag attcgtaaaa gctagctgga acagtcgatc atctgtcctt tcttctttca
     7081 gtgcttcttc taaaggtacg atagctgctt cgaattctcc ttgcatactt aaggattgtc
     7141 ctaaacgttc ctgcatcgag attcctgaaa tttcatttat cccgcttgcc aacaatgttt
     7201 cataaaccac tgctgcctct ttgaaacgat caactgaaaa atacaattca gctagcgcaa
     7261 actggatcaa tggttcatca ggaagcaacc cagctgcttc tttcaatttt gcttcactca
     7321 cttcagggat tccgataact tggtacaaat cagctatcgc caataagctt tgcggatagt
     7381 aatcactttg cttatccact ttttccaggt attcaaaagc taagtcgatc tcattatctt
     7441 cgattgcaat ttctgctaac gggatgttca gtccgtcatt ttctgggtat tggttgatca
     7501 gttgttcaaa aatctgtttt gcttcgatca aaaagccaat agccagcaat tcttcgccta
     7561 gttcagctaa tatatctgct gggtcttctt ttaatgcttt ttctaaaaag atttgtgctt
     7621 gtgacaagtc ttcatctgat aaagcttgca acattttttc gctatttgta ttcatttcaa
     7681 ttccctctta tctcactgac gatttgttga aataccgtca ttgttctcaa taattctttt
     7741 tcgtttggat gttggtatcc gtctattata cctatttttt ctaaaacaag tatttttttg
     7801 cttttttctg ccaaaaaaag aactttttcc aaatactcca tctttgaaat ctgttccagc
     7861 cagtggattg gatagccaag caagtccagc cacacaaaaa agttttttag ttggaaatca
     7921 aaaggatatg cttggagatt ccacacgaaa tgaaacatca ttcctaaaaa ttttttcata
     7981 ctagcagaaa gtagatggcc attttcggtc agataaaaag cttgttcaaa cagtttacca
     8041 taatttgaca ggttttctgc ctctaattga taaaaataga tcatttcttc gatcatcccg
     8101 gcaaacggcc gagtcgttaa ttgcttttta tttggatagt ttttatacag attttgcaaa
     8161 aaacgatgat cacaaatcat tccgcaacag ataaaagtca aaaagtcaat ctgctttccg
     8221 tccacctgcc gctcgctgat tgtttgatca taaacgatgc gttctggcag attgatggtt
     8281 tgcagcacta cacgatttgg tagctgcaaa atcgtccgct gcggtgttaa tgctcggctt
     8341 agagaacgga tcgatacagg gatcatccat agtgatgaat caagggttgt atgtttttga
     8401 aaaaaacctg ccagatccat gatcccttca tttccaaatc cgatgataaa catggattga
     8461 ttttcgggat agcgtttgac gaaatcaagc aggttcttta attctgttaa atgattgcat
     8521 tgagtgttgg cacaaatata ccagtcattg tttgcttgat ttgcaaataa cgggttgatc
     8581 ttatctgcaa acaaatcata atagcgctga ttcgttaaaa ataagattgg ctgatcaatg
     8641 gaaagttctc ttagctgact gactagcgtt tctccgtaaa acactttcgt caacgcatct
     8701 tctacttgat aatcaagttc catacgcatc cctcctcttc ttatttttat tttaccatta
     8761 gtaagcaaat tctagaaaag ataagagcaa agctcacctc ataacttgca aataaataaa
     8821 aattaaataa aatacatgtg ttttctatgt atgacatacg gattcggaat ctctgtctct
     8881 tatttattcc ttttctgcta ggaaataaaa agaaaagcac ttgtagccct agagccacaa
     8941 gcgctttttc aactgtctta tttaacagcg tcttttaatg ctttacctgg tttgaatgca
     9001 ggtactttgc tagctggaat ttcgatttct tcaccagttt gtgggttacg acctttgcga
     9061 gctgcgcgtt cgcgaacttc aaagttacca aaaccgatta attgaacttt ttcgccgtta
     9121 gctaaagcat cttgaatagt tgaaaataca gcatctactg ctgcagttgc atctttttta
     9181 gttaaatcag tagctgaagc aactttttcg attaattctg ctttgtttgc catggataga
     9241 ttcacctcct ccacaagaga tatgatagaa atatcattta gttaaaactt tctgagtggt
     9301 ccagaagttt aaaaagaaat attgattaac ttcaatattc tgttatcacg atatcatatg
     9361 aaccgcttaa tagcaaggtt tttaccaatt ttcacatgct ttttttagtc atagaaacgt
     9421 aacaaacgaa actgtctttt tcttttgaaa aaaaaacgtc gatatggtaa aatgcctatt
     9481 ttctcctacg agggataatt cggatggacg tcccttcaaa agtaaatgct tttctgattt
     9541 gattttctaa gaaacgttca taagaaaaat gcatcaattc ctcttcattg acaaaaacga
     9601 caaatgtagg tggtttgaca gcgacttgtg tagcataaaa aatcttcagg cgttttcctt
     9661 tatctgttgg tgttggattg attgctacag catccataat gatatcattc aacacagccg
     9721 aagagatacg aagattctgg ttcatactta cttgttcgat catttcaggc agacgttcca
     9781 accgttgttt agtcactgca gaaacaaaaa cgattggagc gtaatcaaga taccggaatt
     9841 catcacgaat ctcttgttcg aaatcacgca ttgtattggt ttctttcttt acaagatccc
     9901 atttattcac gacgataata attccacgac cagcttcatg ggcgtaaccc gctactcgct
     9961 tgtcttgttc ccgaatccct tcttcagcat tcagtaccat caaaacgata tcagaacggt
    10021 caatggcacg cattgcacgc atcacgctgt atttttcagt attttcgtat acttttccgc
    10081 gtttacgcat accagctgta tctatcatta agaatttctg accactttca gaaacgaagt
    10141 gggtgtcgat tgcgtctcgg gtcgttcctt caatatccga aacaattaca cgttcttctc
    10201 ctaaaatcgc attgatcaaa gaggatttac caacatttgg gcgaccaatc aaactaaact
    10261 taatcgtgtc gtcgtcctct tcttcagtct cttcagagaa atacttcact gcttcatcta
    10321 aaatatcacc aatccctagt ccatggcttc ctgaaacagg ataaggatcg cctagcccta
    10381 aggaataaaa ttcatagata tcgtttctca tttctggatt atctacttta ttgactgcta
    10441 aaatcactgg tttattactt ctgtataaaa ttttcgcaac catctcatct gcgtctgtca
    10501 cgccttcgcg tccgctgact acacaaatga ttacatctgc ttcttcaatc gcgatttctg
    10561 cttgatgctt gatctgatcc ataaaaggtt catcgccaag atcaattccg cctgtgtcga
    10621 tcacgctgaa ttctcgacct aaccattcac cttttgcata aatacgatca cgagttactc
    10681 caggagtatc ttcgacaatc gagatacgct caccagcgat gcggttaaaa atcgtagact
    10741 taccgacgtt cgggcggcca acgattgcaa ttgttggatt tgccatatta tttcctcctc
    10801 acaagtttcc aatctcactt agtttaacga atgcattgcc aactttcaag catagattgt
    10861 caattaaacg aagtattttt attccttatt gaaatactaa tcgcttttca aaagaaaaac
    10921 tgagacaaaa gcagctgctt tcatctcagt cacagataca aaatcaatta tttttcagaa
    10981 tcatcggttg ctttttcttc tacttcttct ttcaacgcat cacctaaaat gtctcccata
    11041 gtaaatccag tattttcttc tggtaattca taagactcaa cattttttgg ttcttcttct
    11101 gaagctggtt tttcttctaa agctttgata ctcaatgcaa tacgatgttc ttctggatgg
    11161 atctctaata ctttcacttt cacttcgtca ccttcatgaa gcacttcatg tggtgtcgca
    11221 atatgtttat gtgaaatttg agagatatgg actagccctt ctactccagg gaacacttca
    11281 acaaaggcac cgaagcttgt caaacgttta actgttccgt ctaatactgt gccaactgga
    11341 gcttttgtat cgatttctga ccaaggtcca ggctgtgtgt ctttgattga caaggaaaca
    11401 cgttcttgtt caggattgat agacaacact ttgacattta catcatcatt gacagccaat
    11461 acatcacttg gttttgctac atgactatgt gaaatctctg agacatggac tagaccgtca
    11521 attccgccta ggtcgacaaa tgcgccaaaa tcagtaagac gtgcaacacg tccactgaga
    11581 acatctccct catggatagt tgaaagaatt tcttttttct tttcttctct ttcgttttcc
    11641 actaccgctt tatgcgataa gatcaaacga ttttctgatg gttcgatttc gatgatttta
    11701 aagctcaatg ttttgccttt atagtctgaa aagtctgcaa caaaatgatc ttccaccatt
    11761 gatgcaggga caaaaccacg tacaccgacg tcaacgacta aaccgccttt gacaacattt
    11821 gtaacaggtg cttcgatgac cttgccctct tggaaatctc tttcgatatc ttcccaaact
    11881 tttttagcat ctaaacggcg ttttgaaagt agatagctgc cgttttcttt atctttgccg
    11941 atcgtactga taacgactaa atctaataca tcaccgactt ttactacttc gctgatatct
    12001 tctaccggca aagttgataa ttcttttgcc ggaacgactc cttcaactcc agccccttcg
    12061 attccgacaa tcacttgttt gtcttcaatg actaaaactt cgcccttaac aacatcgcca
    12121 acttttactt cttgtacgct tttcattgcg tcttccattg actggttgtt ctcttgattt
    12181 tgatcaaatt ctgtcataac acttgtcctc ctaaccaaca ttctgccgta agtacggtac
    12241 tgtttttagt ttaattgatt attcaaaaaa aataaagcga tttcgttcgt tttccttgaa
    12301 aaaacaattg tttttcattt tttttcttaa tttaaaaaag aagataacct tttttcaaaa
    12361 caacagcttt tattgctgca acgacttctg gaatcgattt gccagtcgta tcgatacgaa
    12421 cagcatcctc tgcttgcttc agcggagaga cgtcccttgt tgaatcataa tggtctcttt
    12481 cctgtatctc tttcgtcagt gtttcaagat cagtcggaat tcctttttct tggttctctt
    12541 tgaaacgtct ttctgcacgc tcacttacgc ttgctactaa aaagattttc acttctgcat
    12601 tcggtaatac agctgtcccg atgtctcttc cgtccatgac aacgccaccg cgttccccta
    12661 tttttcgttg gacagcaact aattcttctc tgacttttcc atgtgcagag acttcagaaa
    12721 cagcttttgt gacatctggt tgacggattt ctaaagtcac atcttttgat gctatgaata
    12781 catgctgtcc atcttcttgt tgcgaaaaag agataggata ctttttgatc agcgaaacta
    12841 gcccttcttc atctgaaaaa gatacattgt tcgtaatagc taaataagtt actgcgcgat
    12901 acatggcacc ggtatctgta taaatataat tcaattcttt tgctaatatc ttggcaacgg
    12961 tacttttccc agatgaagca ggcccgtcga ttgcaatact gatttgtgtc atgatataac
    13021 tcctttttct cagaaaaaaa gccgcaaagc gcggctatta ttatttaatt cttaattctt
    13081 gaccagggta aagcataaag ttgtttggat ctaagccatt caattcaaac aattgatcag
    13141 tggtgatccc tgcacgctca gccacttgtt ttggaccttc gcctgcttga acagtcgttg
    13201 ttgaaccggc tgcagctgat gaagaaggtg ttgtttctgc tgcattgctg cttgaatccc
    13261 ctgcttgata agttgcctca cttgaggaag tcggtgttgt ctctgctgca atactgcttt
    13321 ctgacgttac acctgtatct tgagacacag tagattcttc cgcgattgta ctagattcta
    13381 ctgttgaagt ctcagttgac tcctcttttg ttgtacttgt agaactttct actactgatg
    13441 tcgaagtttc agaagaagtt gctgctgttg cattgttgct tgatccattt ctgatccaga
    13501 aataagcacc tgctggaata gcgatacata agaccagtaa aatcaaaaat agcgaaagaa
    13561 ataatgtatt tcctttcttt tgttgtctct gagaacttct tgatgaaact tcatcatctg
    13621 tatcgtagat tggttgttcc catggttctt gtgtttcgtt attttctgta gattgatgtc
    13681 tatcttttct gctcactgtt ttacctccta aactctatcg tgtgtattat accataggaa
    13741 aaagtgtctt gtcctaaaaa atcaatgttc catgtttttt ttaaataaat ttagtaaaat
    13801 cgtttcccaa tgaagttgtt cagtcttaga aaaaagcttc ctctttggca gaagttctgc
    13861 ttttgctcca tcaatatcac aacaattctg cggcttttcg gagagttttt cgccaaaata
    13921 agctaagatg aattttctgc ggcagttttc ttcattaata tagcgaagca tctgctgcag
    13981 gcggaattct ttttcttttt cctgacgttt gagccgttcc acccaatttt ctggtttttc
    14041 agactgctgg atcagctcca tccatttttt ttgcagctca tcaaagggag cttgctttgt
    14101 ggcatattcc aaataaagct caaaactttg tcgctgttct ctagaaagtt gattaaagaa
    14161 ataatggata cgttcatccc cactttgata aaaaagaatt gctgcacttt cttcctgatc
    14221 tctgcctgct cgaccgattt cttgtacata gttttctaga ctgtctggca aatcataatg
    14281 gaccacataa cggatatcag atttatcgat ccccatacca aatgcattcg tagcaatgag
    14341 aaactgcagc tgatttttta caaactgctg ttgaagttgt cttctttgag ctgcatcaag
    14401 accaccgtga tagtatccaa ctgtaaaacg ttccctgaat aaatgataca atcgttcgac
    14461 ttcttttttt gttgcacaat aaatgattgc cgctccttgt gctctttcca tgaagtgttc
    14521 aagttcttgt tctttttgct gcgttttccg aacaaaaagc gagatatttt gccgattgac
    14581 tgattgtctg atctcttttg gtggtcgatc aaatagtaca tgacgtatat ctcttgctac
    14641 taaatctgtt gctgtcgccg ttagtgccag tgtgaccggg tttcctaaaa gctttcggat
    14701 ttttcctaac tgttgatatt ctggacggaa atcaactccc cattgagaca cgcaatgagc
    14761 ctcatctact acatataacg caatattttg ttttttcaga tgctctaaaa gagaaggatt
    14821 agtcaacatt tcgggactca aaaacaaaaa tttatattgc gatagatgac ggaggacgta
    14881 tcttctttca gattgcgaaa gtaaactatt gaaagcagct actcgtttct cccctcgttt
    14941 ttgtaattgc gtcacttgat cttccattag agaaagcagc ggtgacacga tgatgaccag
    15001 accttccatt aaataccccg tcaattgata gcaaaggctt tttcccgttc ctgtaggcaa
    15061 aatagcgaga gtatcttctc catcaagcaa cgcctgaata atttcttctt ggccgggacg
    15121 aaatgaatca aatccaaaat atttttttaa ttcatttatt aacattctgt atcgcttcct
    15181 ttctcaatag atagatttga tacaaacgaa attctccata atctaattgt ccatctacat
    15241 tccattcgct aaagcgccac tctcgcacgg aatccttatt tggttccaaa cgttcgattg
    15301 tttctgcaga gagaatccac tcgtatggaa aatcatcaaa aaacaaggcc cactcaataa
    15361 gatgatctgt tactgttcct ctttttaaat gacggattgc catgatctgg tcaattgtct
    15421 gaccattcat aaacatctgc ttggtgatca tcatgctttg attgaaattt tgctgtaata
    15481 atgaatcgat caaagcgtgc caaagcgaat ctggccgttt ttcgatttgt gctaacaaaa
    15541 ggtggataca tctgctttgt tgcagataaa cctctgactc atcattgttt tttgccagct
    15601 gataaggaag cagccctgtt cgctcatttc cagataattg gttagctaaa aaatctgctg
    15661 cttcttctgg tatctccgaa aacagctgca ccaaactctc atacgcagta tcaattaaaa
    15721 tttcacgtgg caattggctt tcactaagcc atttttttag ttggaaagta taaaaaggac
    15781 ttgtctctgc tggaagatag tcttgaatac ccgttgccag attagaaatt acttgaacag
    15841 caaatttaat gagccgccaa ctagtttccc ctgttctgcc atagcggtca aaacgcaaac
    15901 cagtatgttc tatttgatgt tcggacaaca tatcagcccc tgcaggcgtt agctttgctt
    15961 cattttcatt tatttcgatc caaccttgct gcgcaatttt ttgcaaaatt tgataaaact
    16021 tatcctgctt caattctgga aaactgttat ggataaacaa aagttcgtgg gtaaatccat
    16081 aaataagtac tgaagtcgtt cgttttccca caaggagttg gtaaagagaa ctaatccgca
    16141 gcttgtgtcc tgatgaaaat agcgataaaa taaaaacaat catattattc tccttaagtt
    16201 aggatggtta gaaatgtcac tactatgtaa acttgtacct gaacgctgta ttgcatgcgg
    16261 tctttgtcaa atcgaagcgc cagatatttt cgattatgat gaagaaggaa tcgttttatt
    16321 tgcccaagaa ccagaggctc atcaacagtt cgtgatgccg gaagaagaaa catatgtaaa
    16381 aaaagcgtat caaaaatgtc cagttcgagc gattttatta gaaaataaaa tataaatata
    16441 aacgaaactt taaaaacgta cactaagttc tctaaacttg aaaataagcc gggatctgtt
    16501 tctcttgttc cgtgaaatcc cgacttattt tgaaagattc atttgctatc tatagttaat
    16561 tgactagttt tttcacggac cctataggac ccatttatat tatttcaact ttttcagcca
    16621 gttttccaat gtattgacga tcacagtttg ctggtctgcg ttagaaattt ctgcctctcc
    16681 atctcctttt tgctcaccat agctgccaaa acctccatga tttccgccat tgattgatac
    16741 atactctgtt ctttccggta aatactgctt agcttcttga taagcttcct gattcaatac
    16801 tttatctttt gtcgccgtga tcgataaaac aggaacagct gattctgtca atgttccttt
    16861 tttgtcggga taacttgcca tgaagaatac cccttttaaa tgtttgtctg aatgattctt
    16921 attgacataa cgacttgcca ttacgccacc taatgaatgg ccaccgatca cataatcgga
    16981 atttggaaaa tcttctttga ccttatccgc tttgtttccg cccatcactg ctagatcaag
    17041 tggcattttg acaatagcga ctgaaaagcc gttttttgct aaatcttgcg cccaaatact
    17101 ataactttct ggctctacga gagcaccagg ataaaaaata agtaatggag actttccatg
    17161 attctttttc tctccttcaa aaaataagta atcttctttg ttttttcctt cttttaccaa
    17221 cacttgcgct tctgacgatg gttcgtacgt attttgctgt atatagtaat aaccggctcc
    17281 accgagtaat cctaaaatga tgactaagcc aattagtatt cgtctaaata ttttcacttt
    17341 ctcccacctt ttctatctga gtgacccctt tttcttaatc aagtatgatt ataccttaaa
    17401 aaaataagag agaaatgcaa actttccagc atcaaataaa aaaagacgga atatccattt
    17461 gaatatccgc cctttttgta tgtttatttt tatttagcac ataaacgata cacagcttct
    17521 gcataaattt ccattgcttt atacatacta cttaattccc atcgttcatt cgcctggtgc
    17581 ataaagtcag gagtatcagg gaacatcgca ccgaatgcca cacactggtt catcgtacga
    17641 gcaaaagtag cgccgcctga tacaaacggt tcagtcatgt ctccagtaat atcgcgatat
    17701 gtccccaata gatttttcac taactcactg tctagtggca cgtataatga atcaaggaag
    17761 tcaaattctt cataagtcaa cccatatttt tctgctgttt tagttaattt agctactaaa
    17821 tcatctttct tgaatgtaac agggattctc atatctacac cgatttttgt ttgttctggt
    17881 gtgatttcca aacttgcaaa gttcatcgtt agctcgccgg attgttcatc ttctgttttg
    17941 cccacgacag cttcaccagt tgcattttct tgaactaatt ttcctaagaa attgattggg
    18001 ccaaaatcaa atacttctga aagagcaatt gccagacgag aaatagcatt cactccttgt
    18061 gctgcatctt tcgcgtggat acttttacca agaacgacga tgccttcacc ttgttcttcg
    18121 aaatcgaatt cgtgtttttt caatgcttct tttacttcag aaagcttttc tccagagtaa
    18181 ggagctgcat caggaacaac attcaacgct cctccagctt ttacagaaaa ctcgttcgtt
    18241 cctggtcctg tcaagtaagc ttgcaataag cctttttctg cataaattaa aggaaattca
    18301 gcatctggcg caaatccttg cgtaattcct tcttcttttt cgttatattt ttctaaacaa
    18361 cgccataaat tttcttcatc tgtaccaaag ataaaacgaa tacgtgtctt gaattccacg
    18421 ccagcatcaa tcaaagcttt gacggcatac attgccgcaa tagaaggacc tttgtcatct
    18481 tgggatccgc gaccaactaa ccagccgtct tttatagttg gatcgaatgg ttttgtttcc
    18541 caattatttt cgtcccctgc tggaacaacg tccatatgac acaagatacc gaataattca
    18601 tctccagagc caatctctga ataaccgtaa tagccttctg gatctttaaa tgttctaaat
    18661 cctagctttt cactgatttc caatacttta tccaaagctt caatcacttt tttaccgaag
    18721 ggatgtcctt gtcctgaatc tgcttcatct agtacggaag gaattcggat caattcgctc
    18781 aatgattcta atgcttgttc atgatgttgt tctgtcacaa attttttcat gatattatcc
    18841 tcctaatatg ttaaaaaggg tcatgtcaaa ttcctccgac acaacctctt cttctcaaat
    18901 aatgacgttt taagcctgct ccatcagcaa gcagaatgtt cttaacaaat gatgaaagaa
    18961 aaaacactca ctgaatggag ctattgactt atccacgtgc ttatcgatag ccgtttatcg
    19021 gtttcttcat tcttatgata gaccttgtac ctgtatttgt ctaggtttag aacattgctg
    19081 ctacacctag gatcacacag atggctacaa ataatatcgc aattaattta ccggtaaatt
    19141 tccaccacac tgaaacatcg aaacgagcaa ttgctacagc acccattacg atagcagatg
    19201 ttggtgtaat taagtttact aaaccagatg cagattgata agcagtgatt actaaatcct
    19261 taccgacgcc ggcaaattca cccataggtc ccatgattcc cattgttgca gcagctaagc
    19321 cggaagttga aggaatcaag aatgacatag ggatatagaa aataaatgta ataatgatga
    19381 atacacttga agataatgaa cttaatcctt gttcgcccca atgtaagatg gtgtctgtga
    19441 ttaatccatt gttcataacc acttggatac cacgagcaac agctactacg attgctacac
    19501 cgatcaaatc agaagcacca gctaaaaatt cagagacaaa ttcagactct ttcatgccat
    19561 aagtgattgc tactacgatg gacattacta agaataacat agtaatttct gggaagtacc
    19621 agtcacctaa tggaagcatg cttttaccta gaaccgtacc tagtaccgga aggtttgtta
    19681 accagtttgt caatgattca aaaatcgtga aattcgcatt caaggttgtc caaggaatca
    19741 aactgatgat catgatacca aaagtaataa agaacaatac attaacatgt ttttgttttt
    19801 tcgtgattac ttcttgacga ccgattgctt caatatcgaa atgcttcata tcttctttac
    19861 gttggttgta tactaatgat tttgttggat ctttttcgat ctttgatgca taacgataca
    19921 catatacaat agaaatagct aacaaaataa cgaacatcaa gaatcgaaga ccaatacctt
    19981 cacccatcga aatcccaaca gcttgtgaag ctacgcctgt tgcaaaagga tttaccgttg
    20041 aagctagaca gcctacttga gaccctacta atacgattgc tacagctact actgtatcaa
    20101 agcctacagc catcatgact gggatcagta aagcatagaa tggaatcgtt tcttctgcca
    20161 ttccgtaagt agagccgcct aatgcaaata acagcatcaa tactggaata agcatttttt
    20221 cttttccttt gaatttcttc acaactgaag caatcccggc atctagtgcc cctgttttgt
    20281 tgataatacc taaaaatcca ccaacaacca aaatgaagaa agagattggg attgcagcag
    20341 gtgtttcttt agttagctcc cccgctggta cacctagcat cccattgatt ggcgccatga
    20401 aaatatccca cagcccttga ggattttgtt gtactcgttc atatgatcca gcgacgatgt
    20461 tgcctgcatc gtctacacta tagtgcccag ctggtataaa ccaagtaagt acagcgatta
    20521 ctgcaataat aataaataag accgtatacg ctgaaggcat ttgaaatttt ttcttttttg
    20581 tttgttccat cttcttcttc ctttcttttc cgttagagac aacaattttg gctctaatgt
    20641 tattttatca aaaagagtat cagaacaaaa ataataacac gcattttgta aaacttttgt
    20701 tcaaaaagtt cgtttttccc tattccctcc tcttttttca ggtttttaaa gctttcttct
    20761 ttttcattgt agcgtttcct tttttttata aacaaacatt ttcgtctttt aaaaggagaa
    20821 gaatttcaca tttgcaaaga attgattgat ttttatgcat aaatcaaaaa aatactcaaa
    20881 acaaacaaat aaaacgttta cattattgca tgtcttgtat ttttttccaa aaaaaaaaga
    20941 ccaagaaatt tcttgatctt tttgatattt atttgactgc tgtatgacgt tgttcgaact
    21001 gatgttgttt tcgacttaac catggaagaa gttgcgcatg cagcactaaa aagacagcac
    21061 tcacgatgaa tcctttgatc aagttgaaag gaacgatccc aatcagtaca tagtttgcta
    21121 aagacatgcc cagcatctgt gttgcgttca gccctaaaaa cattaagtaa agaggcgtaa
    21181 taacgaaata atttgcgata ctcataaaaa tagttagagc gatggttcct gtaatgacac
    21241 ctaaaaattt gtttcttcct ttatgctgtt tctttacact aaagaaataa taaatcggga
    21301 atgtaaagat cgttgttgat aagaaactag cagtgtctcc taccaaatta tccggagaaa
    21361 aacctgtagt cagcagatgt aatactgaac gcaagaacgc tgttgcaact ccggccgctg
    21421 gaccgaataa gaacatgctg atcaataccg agatatcact aaaatcgatc ttcaaaaaac
    21481 taaaagccgg catgatcgga aaagcaaaat actgtaaaac taatgcgatc gcagcaaaca
    21541 tcgctactgc aaccattttc tgtacacggg tgttcttcat ttgaaatcct cctgttagga
    21601 ctcctcttca gcgaactttt tgacgtttct ctccaaatga aaaaactcta ttttccaggg
    21661 aaaatagagt tagagttatt tgatcaagcg tcgtcaaata agctctatct tctttatcca
    21721 gactatactg tcggtatcgg aatttcaccg attcagctat ttttttgcaa aataggtcgt
    21781 ggactataac caccggtcgg gaatttcacc ctgcccctga agacgaacct tatataattt
    21841 ttgtttacat attcattata catatctatt caaaaaacgc aacatctaac acttataaaa
    21901 agtaagtgtt cattttgagt ggttcagcaa actgctgact tcttttttgt tcagttcacg
    21961 gtaatcccca ggacgtaggc cttgtaaagt cagatctccg tatttttcac gttttagttt
    22021 ttgcacagga agaccaactg cttgaagcat atttttcact tgatgattac gtccttcgtg
    22081 gatcgtcaat tccacgatac tgtggtttgt cttaggatcc actgataaaa tttggaattt
    22141 agctggagat gtttttcgtc cttcgatctt tattcctttt gtcaaaggtg caagcatcga
    22201 ttttgtagcg atccctttta cctttgcaac gtaaacttta tccacttcat gttttggatg
    22261 tgtcaggcgc tgagcaaaat ctccatcatt tgtcagtagc aagatccccg aagtatcgta
    22321 atccagtcga cctacaggat agatacgttc ttttaccatc ggcaaaagat ccgtaacaac
    22381 ttttcttcct ttgtcatctg caacagcaga aataactcct ttaggtttgt acaataaata
    22441 gtaaccgtat tcttcttgat aaattgggac ttcatccact tccacagtgt catgtttccc
    22501 aacttttatc cctaattccc ttacaacttg tccgtttact tttacacgtc ctgcaaggat
    22561 gaattcttct gcttttcgac gagaagtgat gccagcgtgg gcaattactt tctgcaatct
    22621 ctccattaca attattctcc tttattcatt ccatcaaaga atagatctgg tgacacgtct
    22681 tcttcaagtg aaatttccat ttcttgtgta tcaggcagtt cttctaatga tttcaaacca
    22741 aaataatcta agaagtagcc agttgttcca tataatatcg gccgacctgg tccttctact
    22801 ctaccttttt cttcaatcag tttatgggca gctagacgct gtaccgctcc tgaaacctga
    22861 actcctcgaa tctgctcgat ttcagctctt gtgattggct gtttataagc gatgattgct
    22921 aaggtttcga cggcggcttg agataatgtg tttgatgtcc cttgcgcata tcgcttaagt
    22981 aagggagcca gctctttttt agtcgttaat acataatggc tttccgtttc aaaaatatgc
    23041 aaagctgagt gcgagttttg agtgtaagat tcttttaatt ctttcactaa acttgtgact
    23101 tctgcttcgc tgagatttaa cagtccgctt aattcttcat tactgatccc ttcctcgcca
    23161 acaataaaaa gaagggcttc aagttcactt aatttcgtca tgttcggtat ctcctactgc
    23221 tggataaagc ataattgatt catagttttc tttttgttgc gcaatgatct gccctttttt
    23281 catcaattct agcaaagcca taaaagtagt gacaacttca cttttagaag gtgactcaaa
    23341 aaaagaatcg aaagtacagc catgcgcatt tctttttata cgctcttcga taaataccat
    23401 tcgttcttcg atcgttgtgt catcgggcgt gatcgttttt tccacttttt gagaaaattt
    23461 cttacgttct aagattttct gcatggcacg gatcaaatcg atttttttga cttgtcctcg
    23521 cttcaacggc ttttcagcat ccgctaaccc atcgatgttc ataggttctt ttgtgtaata
    23581 aagacttcgt tcctctgctt tttctgtcag tctttcagct gcatatttat atttacggta
    23641 ttctaaaagc tgagtgacca attcttctcg aggatcttct tcccataatt cttcatcgtc
    23701 tgtgacgaat tcttggacag gaagcaatgt cttgcttttg attgccatca atgtagcagc
    23761 catcactaag tattctcctg caacagctag ctcgagtgtt ttcattgtat ggatataatt
    23821 catatattgc tccgtgatcg tagcgatcgg tatatcatat atatcgattt ccatttgctg
    23881 aatcagatga agcagcagat cgagaggacc ctcgaataca tctaatttaa tattgatctc
    23941 cgtcaactca ttcactcttt cttctttttc tttgctagcc attttccaat gtaaggctct
    24001 gtgatttcag ttgcacggat ggagacatcc gggtactttt cctgtaattc atctaacatt
    24061 tgaaagccca tattctcacc gcgataagac ggattcaaag aaatgtcatg gatgatcagc
    24121 tgatcgttcg ttgcccagta aataccaata atcccttgaa tgttggttga accttctggc
    24181 gtaaagaaaa aaagttcata atcgtcttca gattcgtacg tatcaatctc cttcaacaaa
    24241 gaagttttac ctgtcagttt cttatggaaa ctcaatagtc ccatagcaat tttacggttt
    24301 tctttccggt aatgtgttaa catcttctca ccttcctatg actaagccct tggaaaatgc
    24361 tgcttataaa catccgtcat tcttttcttc gtgatatgtg tataaatctg agtcgtagag
    24421 atatccgcgt gacctaacaa ttcctgtact gtccgcaaat cagctccatt ttctagcaga
    24481 tgtgtggcaa agctatgccg cagcgtatgt ggtgttactt ctttgtaaat cccagcctct
    24541 cgtactaact gcttcagatt tttccagatt ccttgccgag aaagaccttt cccatgatta
    24601 ttgacaaata catgcatttc agatgcgtcc tttacaagta atggacgtgc ttcgtctaag
    24661 tagcgttcca gccattggat cgcataatca cctaaaggaa tgatccgctc tttatctcct
    24721 tttccaactg tctgtaccag tccaagagaa agatgaagat ctcccaattt caatccaatc
    24781 aattcactga cgcgcatccc agtagcatac atgacttcca agattgcacg atctcttatc
    24841 cctaacgttt ttgtcgtatc aggtgcttca atcagctttt ctacttctgt cagagtcaat
    24901 gtacttggta atttctgtgc tttcttcggc gtatcgatat gttgcatcgg atcatgatca
    24961 gtgatacgct cttgccgtaa aaactgatgg aatcttctga gacttgagat catccgagta
    25021 acagttgctg tcgctttttt ttcttcatgc aacttctcca gaaaacggat gactaaaaag
    25081 cgatcgacat cctgccatga agcaattttc tgctcctgta gaaaatgcaa gtactgttcc
    25141 aaatcacgtt catagctttg tcgtgtattg gcggacaatc cccgttcaat attcaagtag
    25201 tggagataat cgttgatttg ctctttcata ataatccccc tcatgcctct ctatcatatc
    25261 agataccgct tcattctgat agtctttttc cataatctga gcaaagaaaa agccgtctag
    25321 acactcagac ggactggttt cttttttctt tttcatagca ttcctgacag attccatgga
    25381 acgttagccg atgatctttt actaaaaaat gataacgttc ttctactact tgctccactt
    25441 caagtaaaag atcctcttct acttcctcga tcgtgccgca gttcaagcat agtaaatgat
    25501 gatggaaatg tttggcgcct tcttttctca aatcataacg ggctaatcca tcattaaaac
    25561 ttactttatc gacaattttc aattctgtca agatttcaag ggttcgataa acagtagcaa
    25621 gtccaatttc cggactcttt tttttcacta aaaagaagat ttcttctgca gataaatgct
    25681 ctttctcatt ttccaaaagc acaagcagag tagcttctct ttgcggtgtc agcttaaacc
    25741 ccgcttcatg tagctgctgt tttgtttttt tcatcgccga aatagcattc atgaccattt
    25801 actcaacccc aacaatttat aataattaca aataaaaaaa gatataacac tatgttaatt
    25861 aaaattatta taagctagtt aagaaaaaca tgcaagggat tctcaattag attttttgac
    25921 tagttttgtc acaccgtttt cttgtgtaat caatccttgt ttcaaaagat tacctaatgc
    25981 gcgcttaaat gctcctttgc tgataccaaa agctttcatg atttcttctg gatccgattt
    26041 atctgtaaag ttgatttgct gatctgcaga acgttctaaa atggttaaaa tcatttgtgc
    26101 atcatctgat atagcttcat atgctcttgg cttcaatgaa agattcagta caccgtctgg
    26161 tcggacacca atcactcgac cttttatctg ctcgcctaga cgaggttcat tatatcgttc
    26221 agaaggatgg ataaacccaa gatagaaatc ttccgttaaa acgtacgtac ctgttaattt
    26281 caagcggtat gctgttccta tcacatcttt gtttttcatt tcttctgttc catatttgct
    26341 taaagatttg aatatttttt catctgctaa actgccccaa atacggtctt ttgcatcaac
    26401 tctaagggaa atcatcaagc gatccccttt tttaggccat agctctgtca ttgtcggcaa
    26461 ttcatcaaga gatacgacaa agtctttatc tggaagaccg atatcgacaa acgcacctaa
    26521 atcttttcgt gtagcagtaa cgattccaaa agcgtaatga ccgatacggc ttttaggaat
    26581 ttgtgtagtg atccgatttt catgtttttg attttggtaa ccgaatcctt caactgcttc
    26641 accgattttg tgttcacctt ctgatttgct taagccaaag gtttgtccgt ttttttggac
    26701 aaagtagttt ttttcatttt catcaataat aatacctgta aatatagttg ctaataaatc
    26761 gttcattttt ttctccctct atagtgaaag gttttcttaa tacatttctt tgctatcata
    26821 acataatgtt atctacttga atagctgagc cttggtttgg aaaggtgaaa aaaggagtat
    26881 gacaacagtt gtgtcatact cccctttttc gaataaacgg tgttaaacgg caggctcaca
    26941 gcctctttca tttgcctaaa attaattgct cccatttcct ccgaaccatc cagttttaca
    27001 gttgatggtt acgatgtaaa atggcaaagc actttctcca atgcctttca tcaatgcaga
    27061 ttttgttgaa gtggcatata gattataata gccttcccca ttttcgattc tggctttttc
    27121 taatctgtaa cctccttcaa cgatatatcc acgttggata catgtagcaa tcactttgct
    27181 ttggacacct ggtgcccacg tccatgctgg attagatgca tcggcaatat cacttgctct
    27241 ggcagatttg attggctgat tcgctgagtt tgaagaggaa ggggtcgagg atgccgcttc
    27301 ttgctgtgct gcttgtgcga ccgcagcttg ttgagcggct tgagctgcag ctgctgcttg
    27361 agcggcttgt tttgcttgtt cttcagctgc ttttttcgct tcttctgctt ttttcttttc
    27421 ctcttcttct tttttctctt tatcagtgag catcttatct acttgtttca attgttcatt
    27481 caactgagca gatagatctg tatttttcac tttttctact gcttcttttg ccgtcttgta
    27541 ttggtcgcgt gttgctgaat ccactacttt tccgtcttta aagactatag ctgttttttc
    27601 tttagctgtt tgcaattcag catattgatt tttagcttct gtttgtgctt gttgaatcaa
    27661 ttttccaaaa tctgtgttat ccgtttcgat tgcttggatc tctttatctg ctttcaactt
    27721 gatgtcatct gctagatgat catcgacgat ggcaggtgct atgaaccact cattcacttt
    27781 ttggatatct cggatcttag attggatatc ttggtaagtt gtttctaact ctgaatatcc
    27841 tttttcattc ttaagactgg ataaatcatt ttttagtttt gataaatctt gatgaatcat
    27901 atctgcacga ataaattgat ggtgatcatc tgtataaaag gcagcaagtt tctcatgaag
    27961 ttcttccatt tgttgctgtc tttttgcttc tgctgctact tcggcttcta ctttttgatg
    28021 atggtcataa taagcccagc ttcctccacc gagtagaagt actgctgcta aaacgagata
    28081 aggtactttt tttgattttt tcttttgcgc tttatctgga tctgtttttt ctaagtttga
    28141 ttcttgatgt gttttttcag tatctggcac gattgttatt gatttcgctt ctgcttcaaa
    28201 cagcttaggc tggttctctt ctttttctat ttttgcttca agatcagtac cctctttgct
    28261 tacagattga ttttcagcat cggattcact atttatttca tcgggctctg ttgacttttt
    28321 gtctgtgttt tcgagtattt cttttttctc tgcttccggc agtttattcg ttttttcctt
    28381 ttctaattgt ttttcagtaa atacttcagt tttttctgtg atatccgttt ttacgtcttt
    28441 tatttttact gtttctttac ctgtggcgtt ttctctatca gagtcttttt cagtttcttg
    28501 ttccttttct ggctctactt tgttttcctg tgcaattttt tcactgatca ttttgagcag
    28561 ctctttcgcg tgctcttctt ttgtatcttc acgatgtgct ttgatataag cggatagtat
    28621 cgaattttct tcctcattat cgacgatttc tttcagttca gctactcttc ttttttgttt
    28681 tgattcaagc gtttcttctt gattctttcc tgattcttcc gaagtctcat gaacagttgc
    28741 tttcttctgt tcatttttct ctatattagt tacttgatcg tgagcaggtg gttcttcgtc
    28801 ttctggttct gctttttcga ataattccat tacagattct agaggtaaat ctttcaattc
    28861 cgaccattcg attggatcgt ttaattctgt atcaggaaag actgcatctt cagttgattt
    28921 atcctgcata gctgcatctg tatttgtttc ttcaattgat tcttttattt gctgatcttc
    28981 tgcagttatt tgatgaccgc agtctggaca gatagtattc tgctccattt ttttcgatcc
    29041 gcaatttgga cattttttca tcacttagcg atcggctcct ttactaggtt tacgctacca
    29101 tttaatctat catattctat acgtcacgcc aatagcttat ttttaggatt tacttaaaaa
    29161 taatgaatga atttccttcc tatagaaaaa aaagcttgag actgcgtagt ctcaagct
//
LOCUS       DAPBBV010000035        29110 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.035, whole genome shotgun sequence.
ACCESSION   DAPBBV010000035 DAPBBV010000000
VERSION     DAPBBV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.035"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..1030)
                     /locus_tag="RD486_001935"
     CDS             complement(<1..1030)
                     /locus_tag="RD486_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7663662.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLRDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="RD486_001936"
     CDS             complement(1112..1801)
                     /locus_tag="RD486_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7663663.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="RD486_001937"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="RD486_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDT7663664.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="RD486_001938"
     CDS             complement(2328..2831)
                     /locus_tag="RD486_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDT7663665.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="RD486_001939"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="RD486_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDT7663666.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="RD486_001940"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="RD486_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDT7663667.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="RD486_001941"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="RD486_001941"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HDT7663668.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="RD486_001942"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="RD486_001942"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HDT7663669.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="RD486_001943"
     CDS             complement(6443..7462)
                     /locus_tag="RD486_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDT7663670.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="RD486_001944"
     CDS             complement(7635..8540)
                     /locus_tag="RD486_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7663671.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="RD486_001945"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="RD486_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDT7663672.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="RD486_001946"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="RD486_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDT7663673.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="RD486_001947"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="RD486_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7663674.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="RD486_001948"
     CDS             9753..10397
                     /locus_tag="RD486_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7663675.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="RD486_001949"
     CDS             complement(10453..10956)
                     /locus_tag="RD486_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDT7663676.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="RD486_001950"
     CDS             11553..12518
                     /locus_tag="RD486_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDT7663677.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="RD486_001951"
     CDS             complement(12617..13789)
                     /locus_tag="RD486_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663678.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="RD486_001952"
     CDS             complement(13776..14921)
                     /locus_tag="RD486_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663679.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="RD486_001953"
     CDS             complement(14935..15867)
                     /locus_tag="RD486_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663680.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="RD486_001954"
     CDS             15984..17063
                     /locus_tag="RD486_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7663681.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="RD486_001955"
     CDS             17060..17689
                     /locus_tag="RD486_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7663682.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="RD486_001956"
     CDS             complement(17799..18026)
                     /locus_tag="RD486_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7663683.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="RD486_001957"
     CDS             complement(18129..20717)
                     /locus_tag="RD486_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDT7663684.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="RD486_001958"
     CDS             complement(20737..21396)
                     /locus_tag="RD486_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7663685.1"
                     /translation="MALYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="RD486_001959"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="RD486_001959"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDT7663686.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="RD486_001960"
     CDS             complement(22169..23035)
                     /locus_tag="RD486_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7663687.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="RD486_001961"
     CDS             23144..23785
                     /locus_tag="RD486_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDT7663688.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="RD486_001962"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="RD486_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDT7663689.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPLKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="RD486_001963"
     CDS             complement(25226..26125)
                     /locus_tag="RD486_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7663690.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="RD486_001964"
     CDS             complement(26127..26924)
                     /locus_tag="RD486_001964"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HDT7663691.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="RD486_001965"
     CDS             complement(26902..27606)
                     /locus_tag="RD486_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDT7663692.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="RD486_001966"
     CDS             27737..28312
                     /locus_tag="RD486_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HDT7663693.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="RD486_001967"
     CDS             28430..29107
                     /locus_tag="RD486_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDT7663694.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8566 a         6167 c         5234 g         9143 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtccct taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag tgccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta gtggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaaaaa
//
LOCUS       DAPBBV010000036        26656 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.036, whole genome shotgun sequence.
ACCESSION   DAPBBV010000036 DAPBBV010000000
VERSION     DAPBBV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.036"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     regulatory      95..174
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            172..1365
                     /locus_tag="RD486_001968"
     CDS             172..1365
                     /locus_tag="RD486_001968"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDT7663695.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1495..2967
                     /locus_tag="RD486_001969"
     CDS             1495..2967
                     /locus_tag="RD486_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7663696.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3050..3838
                     /locus_tag="RD486_001970"
     CDS             3050..3838
                     /locus_tag="RD486_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDT7663697.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(3905..4573)
                     /locus_tag="RD486_001971"
     CDS             complement(3905..4573)
                     /locus_tag="RD486_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HDT7663698.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYNLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGIKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            4688..6400
                     /locus_tag="RD486_001972"
     CDS             4688..6400
                     /locus_tag="RD486_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663699.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6403..8172
                     /locus_tag="RD486_001973"
     CDS             6403..8172
                     /locus_tag="RD486_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663700.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(8377..8943)
                     /locus_tag="RD486_001974"
     CDS             complement(8377..8943)
                     /locus_tag="RD486_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7663701.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(8943..9899)
                     /locus_tag="RD486_001975"
     CDS             complement(8943..9899)
                     /locus_tag="RD486_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDT7663702.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(9899..10555)
                     /locus_tag="RD486_001976"
     CDS             complement(9899..10555)
                     /locus_tag="RD486_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDT7663703.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            10925..12943
                     /locus_tag="RD486_001977"
     CDS             10925..12943
                     /locus_tag="RD486_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7663704.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFSARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    13013..13219
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13370..15784
                     /locus_tag="RD486_001978"
     CDS             13370..15784
                     /locus_tag="RD486_001978"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDT7663705.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            16132..17685
                     /locus_tag="RD486_001979"
     CDS             16132..17685
                     /locus_tag="RD486_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDT7663706.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(18066..19850)
                     /locus_tag="RD486_001980"
     CDS             complement(18066..19850)
                     /locus_tag="RD486_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663707.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(19865..21586)
                     /locus_tag="RD486_001981"
     CDS             complement(19865..21586)
                     /locus_tag="RD486_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663708.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            21686..22447
                     /locus_tag="RD486_001982"
     CDS             21686..22447
                     /locus_tag="RD486_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7663709.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            23414..23682
                     /locus_tag="RD486_001983"
                     /pseudo
     CDS             23414..23682
                     /locus_tag="RD486_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            24354..>26656
                     /locus_tag="RD486_001984"
     CDS             24354..>26656
                     /locus_tag="RD486_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663710.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVET"
BASE COUNT         8575 a         4670 c         5541 g         7870 t
ORIGIN      
        1 ttttttggac agttctaatg taaaatattt ttatattttt taagcaaaaa aatgaaaaaa
       61 tacgagcaga aaactgtttt atctgctata cttggttcgt tgcaagttcc cgaaaggatc
      121 cgcaggacgg agatgccttg taaccgaatt taactagggg gaatcattat aatggtagaa
      181 agacacttat ttacatcaga atctgtttct gaaggacatc cagataaaat tgctgaccaa
      241 atcagtgatg caatcttgga tgcaatttta aaacaagatc caacagcacg agtagcgtgt
      301 gaaacgtctg taacaactgg tcttgtttta gtatttggag aaatatctac gacggcatat
      361 gtagatattc aaaaagtcgt acgggaaaca ataaaagaaa ttggttatac acgtgcaaaa
      421 ttcggatttg atggagatac agcagctgta ttggttgcga ttgatgaaca atctcctgat
      481 attgctcaag gagttgatga agcacttgag atccgggatg aagataaaaa agacgtatta
      541 gatgagattg gtgctggtga ccaaggttta atgtttgggt ttgctgtaga tgaaacacca
      601 gaattgatgc ctttaccaat cgctttgagt catcgtctgg tacgacgctt ggcagatttg
      661 cgtaaatcaa atgaattaac gtatttacgt ccagatgcaa aatctcaagt aacggttgaa
      721 tatgatgatc aaggacaacc ggaacgcgta gatacaatcg ttatttcaac acagcatgat
      781 gatgcagtag ataatgaaac aattcgtcat gatgtcatcg aaaaagtagt gaaggaagtt
      841 attccagctg aattattaga tgatcaaacg aaatattata tcaatccgac tggccgattt
      901 gtcattggtg gtcctcaagg ggatgccgga ttaacaggaa gaaaaatcat tgttgatacg
      961 tatggcggtt atgctcgtca tggtggcggt gctttttctg gtaaagatgc gacaaaagtt
     1021 gaccgttctg ccagctatgc tgcacgttat attgctaaaa acattgttgc agcagggctt
     1081 gctcgcaaag cagaagtaca gctagcttat gcgattggtg ttgctcaacc tgtttcgatc
     1141 tcaatcaata ctttcggtac tggaacggtt ccggaagaag aactgattgc tgcagtgaga
     1201 gaaaacttcg atcttcggcc agcaggaatc atcgagatgc ttgatttgcg tcgtccgatt
     1261 tacaaacaaa cagctgctta cggtcatttt ggtcgtacag atgtagattt gccttgggaa
     1321 catacggaca aagtagatgc gttgaaagca agtttagcaa aataagttat attcagctgg
     1381 aacgatcgcc aagtggtggt tgttccagct ttttttatgg cagttaacct cttgaaaaag
     1441 atagtaatta tttatctatt tttagatcct gtcataatga aagggaggaa taagatgaaa
     1501 aaagaaacaa atgttacttt ggtcacagtg agtattttca ttgcaacgtt catgacggct
     1561 attgaaggta caatcgtaac aaccgctatg ccaacgattg tcggttcatt acatggaatg
     1621 gaaatcatga actgggtatt ttcgatttat ttgctgacaa acgctatgct tactccgatt
     1681 tacggaaaac ttgcggataa agtgggacgg aaaccaatct ttatttttgg gacattattg
     1741 tttattatcg gttcgttatt ttgcggttta tctcaaagca tgattgggtt gattgctgct
     1801 cgtgcgattc aagggatggg tgctggggca atgatgccag tagctttgac gatcatcggc
     1861 gatctttatt ctattgaaaa gcgagcaaaa gttttaggtt tgaatagttc agcctggggg
     1921 attgccagtg tttttggacc gcttgcggga ggattcatcg ttgaaacgat cagctggcac
     1981 tggatctttt ttatcaatgt gccgatcgga attctattaa ttattttgat ttggctatat
     2041 ttaaatgaac caaaaatcat acatgagtct aaaccaatgg atatttttgg tagttttagt
     2101 ttgatggcca tgcttgtctc attgctgtta gggttccaat tattaggaga cgaaggaatg
     2161 agtccgcttg tttctgcttt gctgctaggt agtatcgtaa tgttaggtat ttttgttttt
     2221 gccgaaaaaa gagctaaaga tcctgtcatc atgatgcatt tattcaaaaa tccactattt
     2281 gttgtggtca acttggctgc agcattggct agtggttttt tgatgggaat cgatgtttat
     2341 atccctatgt ggatgcaagg tgtattaggg ctgaatgcag caattggtgg gctggtatta
     2401 gcaccattat cactagtctg gatggtcggt tctttccttg caagcaagtg gatgactcaa
     2461 atgaaaactc attgggtctt gagaattgga ctactaatcg cagctattgg gggcgcttgg
     2521 ttgtatctta tgcctttcag aagtaactat ttatggtttt ttgctatatc aacggtcatc
     2581 ggtataggct taggtgtgac catgactacc tcgactgtca gtgcacaaaa tagtgtatct
     2641 cgtgaccagc ttggtgtagc aacttctttt aatacgttag ttcgaacaat tggtcaaaca
     2701 gtcatggttt ctatttttgg tttattgata aatggggtaa ctaaacgaga acttgcagca
     2761 gcaaatttaa caaatgatgc agatatcatg aataaactgg tgaatccaca aacggctaaa
     2821 tatattgatg cggatatttt gttaccatta agaaaaattc tttatgatgg gttacattcc
     2881 gtttatctag ttggcttgtt actcgtgatc attgctttgg tcttaacgct tttcgttcat
     2941 gaaaaaagtg gtaaaataaa acagtagttt cggttaagat atgtacgtag ccgaatcatt
     3001 caaatttaaa gttattcaaa aataacttct tactaaggaa ggcgaaaata tggcatttat
     3061 tcaagcaaat atttattcga atgtgttaga aatggaagtc aatctaaatg tgatactacc
     3121 gcaaacaaca aaaaaggtga ttggcaccag ttcagagcaa gagacaacgg atatacctgt
     3181 tttatattta cttcatggaa tgggtggcaa tcatagtgta tgggaaagac gtacgtcgat
     3241 tgaacgttat gtagcaaact acggattagc tgtcatcatg ccatctactg atcttggctg
     3301 gtacacagat acagtttatg acatgaagta ttggacattc attgcagaag agctacctga
     3361 gatttgtcat gaattattcc cgcaattaac aagaaaaaga gaaaaaacat atgccgctgg
     3421 attatcgatg ggcggatatg gcgcgttaaa actaggcctt gcaaaatcag aaaatttcgc
     3481 agcagtaatc tctctttcag gcgctgtttc tgtaggaaat cgaatggatg atcttttgat
     3541 ggttcgtaaa gcatcttttt gggaagggat ctttggacca ttggatcaaa tcgaaggttc
     3601 aaaaaatgat ccgcaatact tattgaaaga actagtaaaa agcggaaaac cagttccaag
     3661 attttatatg gcttgtgggg aatctgattt tctttatcag gcaaatcagg aaatggtatc
     3721 tgctatgcag gaacaaggct tggcggtcac ctttgaacaa ggacctggcg atcataactg
     3781 gatcttctgg gaccaatgga ttcaacgtgc attggcgtgg ctaatggaag aaaaataaaa
     3841 aaagagtctt aaaaagatag ctcctataga gatcacaaac atagtgatct ctataggagc
     3901 ttttttactg ctcgttttct cttcttttat tttgttggca taagccttca atataggttt
     3961 gtgcactcgt tagaaagagt gctttttcat tcaattctgc atgggactgc atactttctt
     4021 taattccctc taattgattt tcaactacat aattacgcat aaatagaact gtttctttca
     4081 aaaattcatt tccgtccata attttttgtc gaagctgctg ttcatgctgc tgatccatta
     4141 actgtccaat caataaattg tggagagagg caatggcctg atgactttgg gtgactgaaa
     4201 atccttcacg aacaagtaat tggatcattt gctccaaatg ttctaatcga ctcggaaaag
     4261 cgggcacagt attgatttct aattctgccc cacaagggaa acgtgtataa aggttatagt
     4321 aattttccat atactgcagc aactgttcat tccaaggcaa agttggatct ggaagcgcta
     4381 attcttcttc cattgtttca gccatttttt gcaagagctg ttgtttgttt ttgaaatacc
     4441 aatataaagc aggtgcttga acatgaattc tgtttgcgat gtttcgcatg gaaagctgcg
     4501 aaagagcttg tgtttcagcc aggatatcaa aggcggcctg aatgatgatt gcttgagaaa
     4561 gctttatttc cattttatca acctcgtgta ttgcattatc tttttaaaca tggtaaattg
     4621 ttagtcggtc taattttaca gtgttaaatt agtcctgtca atttaaacaa aggggtgtaa
     4681 tcaacgaatg aaattaatct tacgacatgc gaaaaaatat aaagtagctg tttttatttc
     4741 cttgctgtcc gtagcagtca tggttgcagc agcattatgg caacctaagt tactacagca
     4801 agtattggaa gctattatta cagaagataa tgatgaaatg aaaacaattg gtatttacct
     4861 gatcagtctg gctttgctag gattagccgc aggtgtaacg aacacgattt tctctgcaaa
     4921 agtagctcaa ggcgtaagtg cagatatccg agaagaagca tttcgaaaga tccagacatt
     4981 ttcatttgga aatatcgaac agttctctgc tggaaatctt gttgttcgtc taacaaatga
     5041 tatcacgcaa atccaaaatt tagtgatgat ttctttgcaa tcactttttc gaattccatt
     5101 cttatttatt ggtgccttca ttttagctat gatcacgatg ccgcaattat ggtggatcat
     5161 cgtagcgctt atcgttacgg tatttctgat tacggcactt tcatttacaa ggatgggcaa
     5221 gcacttcatg atcattcaaa aactgattga tcgtgtgaat agcattgcaa aagaaaactt
     5281 actagggatt cgtgtagtga aatcttttgt acaagaagaa aaccaattga agtcattcag
     5341 caaagtaagt gaggacttaa caaaacacaa catcatagtc ggtacattat tttctgtgat
     5401 gatcccgtcc ttcatgctgg ctgccaattt ggctgtggtt ggggcgatct tttttgtgag
     5461 cgatcttgtt aaagatgatc ctacgttaat tggtggaatt gcttcattca tgaactactt
     5521 gatgcagatt atgatggcaa tcattattgg cggaatgatg atgatgatga cttcaagagc
     5581 agccgtatcg ctgaagcgga ttgcggaaat tttagatgct gaaccagatc ttacttattt
     5641 agacgttcca gaacaagagt tgacgggttc tgtcactttt gaccatgttt cttttcgtta
     5701 tcctggtgag gatacagata cgcttaaaga tatcagcttt tctatcaaac ctggagaaat
     5761 ggttggtatc gtcggggcga ctggtgccgg gaagtcaaca ctagcacaat tgatccctcg
     5821 tctatttgat ccgacagaag gcaaagttga agtaggtggt gtagatcttc gtcaagtaaa
     5881 tgaaaagagt ttaagacaaa cggtttcctt tgttttgcaa aaagcaattt tattctcagg
     5941 aacgattgct caaaacttgc gccaagggaa aaagaatgca acagaaaaag agatggaaca
     6001 tgcttcttct attgctcaag caaaagaatt catcgaaaag ttatctgatc gttacgaagc
     6061 accaatagaa gaacgtagca gtaacttttc tggtggtcaa aagcaacgtt tatccattac
     6121 tcgtggcgtt atcggtaatc caaagatctt gatcctagat gacagtacga gtgcactgga
     6181 tgctcgctct gaaaagctgg tccgagaagc actcgatcga gatttgaagg gaacaacgac
     6241 gattgtcatc gcacaaaaaa ttgcttctgt tgtcaaagca gaccgcatct tagtattgga
     6301 tgaaggcaga ttagtcggcg aaggaaccca tgaggaattg gtagctggaa accgtgtcta
     6361 tcaggaaatc tttgaaactc aaaaaggaac ggaggagtaa gtatgactga tctaataaaa
     6421 gcaagtaaat ttttctatca ctatttgaag cggtacaaac tctccttttt ctttatcttt
     6481 atcacagtga tcattgctac ctatctacaa gtaaaggcac ctcaatacat cggggaagct
     6541 tttcaagaat tagctaatta cgtaggaggc ttgatgcaag gcgtagacga taaaagcaaa
     6601 tttgtttctg taatatggaa actcttgctg ttttatgtac tagctagtgc agccaacttt
     6661 atctatagta ttttgttcac acaagtagta gggaagtcaa cgaaccgaat gcgtatcggt
     6721 ctattcaaca aattggaaaa attgacgatc cgtttctttg attctcatca agacggtgaa
     6781 attttaagtc gttttaccag tgacttagat aatattcaaa atagtttgaa ccaagctttg
     6841 cttcaagtca tcacgaatgc tgttttactt gtcgggatct tgatcatgat gttccgccaa
     6901 aatgtagagt tagcttgggc tacaattgct tccactccag tagccgtttt gatagctgtc
     6961 ttgattatcc gcaaagcacg gaaatatgtg gatcttcagc aagatgaagt ggggaaacta
     7021 aatggttata tggatgaaaa aatcagcgga caacgtgtca tcatcacaaa tggcttacaa
     7081 gaagaaacga ttgaaggatt cttagagcat aatcaaagtg ttcgcgaagc aaccttcaaa
     7141 ggacaagctt attctggtct actatttccg atgatgcaag gaatgtcact ggtcaataca
     7201 gcgatagtta tctttttcgg cggctggtta gcattaaatg gtgatttgga acgttcggtg
     7261 gcattaggct tagttgtgac attcgtccag tattcacaac aatattacca accactgatg
     7321 cagatttcat ctggatacag catgatccaa ttagcgatta caggggcaag acgattgaat
     7381 gaaatatttg atgaaaaaga tgaagtcaaa ccagaaaacg gtaaagcatt tgatggtgtt
     7441 gaaaaaggtc ttgcgttgca gcacgtagat tttggttatt ctccagaaaa actagtcttg
     7501 aaagatgtct cgatcaatgt ggacaaagga gaaatggttg ctcttgttgg tccaacagga
     7561 tcggggaaaa cgacgatcat gaatctgcta aaccgttttt acgatgtcaa tgatggttca
     7621 gtagtcatcg atggaataga tatccgagat tatgatcttg atgcattacg tagacatgta
     7681 ggaatcgttt tgcaagaatc tgtattgttc tccggaacga tcaaagacaa tatcacattc
     7741 ggcaaaccgg acgcttcaga tgaagaagtc atcaatgcag caaaacaagc gaatattcat
     7801 gacttcatca tgacgttaga aaaaggttat gatacagaga tatccgaaga aaataactta
     7861 ttcagtacag gtcaaaagca gttgatcagt attgctcgaa cgatcatcac aaatccatct
     7921 ttattgattt tggatgaagc aacaagtaat gtagacacgg taacagaagc aaggatccaa
     7981 aaagcaatgg atgaagcaat caaaggaaga accagctttg tgattgctca ccggctgaaa
     8041 acaatcttga atgcagatag aatcgttgtc ttgcgtgatg gggaagtcat tgaagaaggc
     8101 agtcatcacg agttattagc agaaaatgga ttttatgcgg aactttatca taatcaattt
     8161 gtatttgaat aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat
     8221 caaaaacagc ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt
     8281 gagcaccgtg aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa
     8341 acgcaaaaca tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata
     8401 taaaataggc ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc
     8461 ctgtggcagt ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg
     8521 accatagtag acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc
     8581 catagctgtg cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata
     8641 ccctagattg aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt
     8701 ttcgtggcct tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc
     8761 acgagtagca tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc
     8821 gatgtgttct gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg
     8881 atcccctggt tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa
     8941 catcagacgc tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga
     9001 agttcttcat caattgcatt caagacttcc cattttttca agctccacat tggtccaatc
     9061 aaggaatccc acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt
     9121 tccagctggt cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct
     9181 tcatgatagt cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt
     9241 ccttggatat ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt
     9301 tcgcctggta atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta
     9361 gccacgccat ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct
     9421 tcaaaagttg tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca
     9481 aggtaatcaa ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg
     9541 acacctggta aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg
     9601 gtgtttgtaa aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc
     9661 atcatgtcga tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg
     9721 tctcccgaac cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga
     9781 ttcggacagt caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt
     9841 cgtaaagcgt aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt
     9901 aaaagtcctt ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat
     9961 aagtcaggca cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat
    10021 gaacgcccag ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt
    10081 gaagcaatgt gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac
    10141 cgtaaagaat catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta
    10201 ctaagtgcgc caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga
    10261 ttccagcaat tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat
    10321 accacatcca taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt
    10381 tagtcataaa gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa
    10441 accactgatc gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga
    10501 aaaacaggac aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat
    10561 tcctcctttg aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag
    10621 agataaaacc aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact
    10681 gtaatcggaa agacattttt tggtaatgca aatgaaatgt tagtgaaata aaatcagtgt
    10741 ttttcgaaat ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag
    10801 ttgttcatta cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt
    10861 ttaataaata ttaagagaag ttataattat taataataga taaattgaag ttggaggata
    10921 gaagatggaa aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg
    10981 aaaagcaaaa cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc
    11041 cccattagta cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcagcgcaag
    11101 aatcaataca gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc
    11161 caacgatcta tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag
    11221 tagtgcgtta tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg
    11281 acaaaccgtc tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga
    11341 gcctttccga caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag
    11401 aaatacttca tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc
    11461 ctatacagat gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg
    11521 caaattaaat aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg
    11581 aaacgcaggc ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg
    11641 cggttcaagc aattctggta atacaaactc aggttcagca acttcgacca cttatactgt
    11701 ccaatctggt gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt
    11761 gatccaatgg aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa
    11821 aggtagccag gaaaatggct cttcgacgaa taattccggt aacaatacca attcttcagg
    11881 aaatgctggt acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg
    11941 tgattctgtt tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg
    12001 gaacaatatc aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg
    12061 ttcttctaat gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc
    12121 gtccagctca agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga
    12181 ctctgtttgg agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa
    12241 caatatccaa aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc
    12301 aacaaacagc acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt
    12361 taatactggc agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg
    12421 gagcgtggca aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa
    12481 aaacaacttc atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac
    12541 aaatacaggt tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac
    12601 aagtacatca tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag
    12661 cgtagcgaac aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa
    12721 taatttcatc tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa
    12781 ccaacaatca gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag
    12841 tgttgctgac agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa
    12901 caactttatt tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa
    12961 ataacgattg aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac
    13021 ttgaaaagga agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg
    13081 cacggatgct tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg
    13141 gcggtgacgg ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg
    13201 cgtagattac gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg
    13261 aagtttgaga aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt
    13321 tatatttata atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa
    13381 tcataaagaa attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac
    13441 ccatgatgat cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg
    13501 tcaagggcta catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt
    13561 gaaaagaagt caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc
    13621 tgctgaacaa tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat
    13681 cgaaacattc cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt
    13741 gaatacaact gatccggagt attataaatg gacacaatgg atctttacga agctttatga
    13801 aaaaggtcta gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt
    13861 tatttcaaat gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag
    13921 aaaaccaatg cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga
    13981 tctagaatta gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg
    14041 ttcagtagga gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt
    14101 tacgacacga ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga
    14161 tcttgttaga gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga
    14221 gacagctaaa aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt
    14281 tactggtgct tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga
    14341 ttatgtatta tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg
    14401 tgactttgaa ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga
    14461 tgttgaaaaa gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg
    14521 catgaacaaa caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg
    14581 gaaaaaagaa gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg
    14641 tgaaccaatc ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga
    14701 gctaccatta cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc
    14761 attagcaaat atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg
    14821 tcgcgaaacg aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat
    14881 cgaccctcat aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt
    14941 tgacatctac attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg
    15001 gcataaattc ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata
    15061 caatcaagga atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt
    15121 agtcaatcct gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat
    15181 gttcatgggg ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg
    15241 taaattcttg gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg
    15301 tatcactaca ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt
    15361 gacagaagac tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat
    15421 caatgaagcc tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact
    15481 actcgcaccg attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg
    15541 tggtatttct tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt
    15601 agaagttgtt ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt
    15661 aggaaaagat gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga
    15721 aggcaaaaca gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa
    15781 ttaattggct ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa
    15841 tgaacttcat tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa
    15901 aggttttgat tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt
    15961 aagagatctc tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa
    16021 actacctgaa attgagagta cataccaaat tcataaattt tttattagtg ggactagtga
    16081 ttgtatggat tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa
    16141 gaactattta ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa
    16201 agagcgaaaa gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt
    16261 ttcggagctg tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg
    16321 atgcaaaaat taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt
    16381 gtgcttattg tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc
    16441 gatcaatggc ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat
    16501 gatgactatc tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt
    16561 gattgccagt tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa
    16621 tcaaaattcg gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa
    16681 aaaagccagt cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt
    16741 tttttcctca ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg
    16801 tcttctcata taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata
    16861 caaaagacaa atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa
    16921 aagataaatg atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt
    16981 ggtgctaatt gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc
    17041 ctgacaacgg ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc
    17101 gatttctcat ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat
    17161 aatggtaaaa catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga
    17221 aaagcggtat tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct
    17281 gcagaaactt tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga
    17341 agtacaatga tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt
    17401 gtttcgacac gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca
    17461 gttctgtcga ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat
    17521 gaagttactc aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga
    17581 ccaatcgatg cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca
    17641 tggcaattcg ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg
    17701 agcctgacgt tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg
    17761 ttgaatagtg taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta
    17821 tagcttctcg tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg
    17881 tttattcgta aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa
    17941 ggagctatcc aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta
    18001 catttaaaaa agctatcgat catggactaa tcatacatga tcgatagctt tttagataat
    18061 gtttgttacg ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg
    18121 agtagttcag aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg
    18181 tctgcatttt caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc
    18241 acagcttcca ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct
    18301 tcatctaaaa taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt
    18361 tgctgtcctt gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc
    18421 agtgttcgaa taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt
    18481 gtggcatcca ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta
    18541 ttttgtaaaa ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca
    18601 agaccgtcga attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact
    18661 aaagtcgttt ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact
    18721 gaaaaatcga cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg
    18781 aaagctattt ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca
    18841 tctgtttcat ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag
    18901 ttgatcacat aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa
    18961 gcttgtaaga agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca
    19021 cttatgatga aggcgagttg attaatgaaa cgaatggccg gatagatagc aaagttcata
    19081 aattgagcac gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct
    19141 gcatgagctt gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt
    19201 cgattattta aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc
    19261 gcaatcttag ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc
    19321 ttgctttcga tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa
    19381 aattgattga tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga
    19441 ctaatgatgt cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt
    19501 tttgtgattt cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt
    19561 tcctgaataa atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg
    19621 aacaacaatg cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt
    19681 tctgataaga gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg
    19741 ttcccgaata aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt
    19801 ttccaaaaac gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt
    19861 ctttctatat tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt
    19921 cttcatgagt accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt
    19981 gttggattgt actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat
    20041 gaagggctgc tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga
    20101 atacatagat ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc
    20161 cccctgaata attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt
    20221 ccactagttc ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat
    20281 attcatttcc catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag
    20341 ggacataact gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac
    20401 caagggttac ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac
    20461 tttttccaga tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat
    20521 caatatcttc tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag
    20581 cagctgcatt tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa
    20641 tttcgatctc tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga
    20701 taatgaccaa taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga
    20761 ctacagcagt cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc
    20821 acaaaataga agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa
    20881 atattcggtt cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct
    20941 tttcttcata tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc
    21001 tcaatgtgat ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc
    21061 gtttcatcag tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg
    21121 ttagtaatag agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg
    21181 gtaagatcat ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca
    21241 ttcttgtcaa aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga
    21301 atttacggaa atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa
    21361 agtaactaga ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc
    21421 caattttttt tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta
    21481 ctaattttgg tacacctaat gtaccggcga tttgtaaaca gatcatcaca aaggtaagga
    21541 gagcgagtcc tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt
    21601 tttcctgata cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa
    21661 taaactgaaa aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga
    21721 actatttgat ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc
    21781 aagtagacaa gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta
    21841 tgatatcgtt ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg
    21901 aaaaacattg acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga
    21961 actggtggtg atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt
    22021 gatgatcgat acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat
    22081 ctcaacggag tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt
    22141 tgggatgatg agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc
    22201 tagtgaagta catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta
    22261 tcgtcgattc ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat
    22321 cagagaaaga atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt
    22381 gacgaatacg gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa
    22441 aaaataggaa atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa
    22501 aaattttctg gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa
    22561 ttttagtttt ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata
    22621 tatacgatgt aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt
    22681 ataattcatg gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt
    22741 gtatcagatg agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt
    22801 gttgcttaca ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac
    22861 atatttttta atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga
    22921 tagcattttt ttgcttataa aataattata agtatttaga gatttttctt ctaacattct
    22981 tcaaacaaga aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt
    23041 gtttttttat agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat
    23101 ttggtaatat tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt
    23161 tattttttgg aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa
    23221 aaagcagtat gactaatata aatactattg tcatttatgc aattttttat ggatagtaat
    23281 tttagagggg aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt
    23341 agcaaaaata gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga
    23401 atcaactaca acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga
    23461 aaaggtagtt attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac
    23521 cctttgcaat atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat
    23581 ttaatacaga ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct
    23641 aagaagatga ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc
    23701 aaataaagag caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg
    23761 gtggacagtt tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc
    23821 ctaaatgcgt ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc
    23881 gatgaatccc aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt
    23941 tttgggattg atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac
    24001 cttggtatca acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca
    24061 ttaacaaaat aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc
    24121 gtgaaatcat aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa
    24181 tcaatcaaca gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct
    24241 tgagttgaac cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt
    24301 agaaaattat cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga
    24361 acaaatttca taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg
    24421 ggaacataac ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg
    24481 aagttgatca agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac
    24541 cagacctgct aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga
    24601 agcaactcaa tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg
    24661 aattgaccgc aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac
    24721 cagaagaaag cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta
    24781 atataccaga agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta
    24841 taacgcagga atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct
    24901 ctgctgagcg ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag
    24961 gaggcgctgg cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat
    25021 cgattggctt aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac
    25081 tggcatttta ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat
    25141 taaatgaagc cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat
    25201 caggcggtac tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag
    25261 caaacacgga attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat
    25321 actatggctc tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc
    25381 aagacgtgac caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag
    25441 acggtgtagt ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta
    25501 catggagttc cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa
    25561 cgaatccagg tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag
    25621 tatcttttaa taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc
    25681 aatcgtattt tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa
    25741 gacaagagga tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga
    25801 gccgagacta ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa
    25861 gtgtggacaa aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct
    25921 cgatgttttc tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg
    25981 aatttgtgtc atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa
    26041 tagttcgttt cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta
    26101 aggtcaatgt agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga
    26161 atagtgacaa tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta
    26221 aagtaattaa aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat
    26281 caagcgattc acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg
    26341 aaccgcttcc tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt
    26401 tagatgcgac ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa
    26461 ccattgaaaa catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg
    26521 gtgaagtcct tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa
    26581 ccggtttaac tacaggagaa gatggaaaac tggcaattga cggtttagca ccaggagcat
    26641 atcagctggt agaaac
//
LOCUS       DAPBBV010000037        25986 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.037, whole genome shotgun sequence.
ACCESSION   DAPBBV010000037 DAPBBV010000000
VERSION     DAPBBV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.037"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            185..1183
                     /locus_tag="RD486_001985"
     CDS             185..1183
                     /locus_tag="RD486_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7663711.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="RD486_001986"
     CDS             1295..1804
                     /locus_tag="RD486_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HDT7663712.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="RD486_001987"
     CDS             complement(1834..2493)
                     /locus_tag="RD486_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDT7663713.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="RD486_001988"
     CDS             complement(2495..3259)
                     /locus_tag="RD486_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HDT7663714.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="RD486_001989"
     CDS             complement(3267..3944)
                     /locus_tag="RD486_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HDT7663715.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="RD486_001990"
     CDS             complement(3981..5366)
                     /locus_tag="RD486_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7663716.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="RD486_001991"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="RD486_001991"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="RD486_001992"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="RD486_001992"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HDT7663717.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="RD486_001993"
     CDS             6305..7162
                     /locus_tag="RD486_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663718.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="RD486_001994"
     CDS             complement(7243..7578)
                     /locus_tag="RD486_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663719.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="RD486_001995"
     CDS             complement(7645..9015)
                     /locus_tag="RD486_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDT7663720.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="RD486_001996"
     CDS             complement(9093..9629)
                     /locus_tag="RD486_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7663721.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="RD486_001997"
     CDS             9938..11419
                     /locus_tag="RD486_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663722.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11522..12229)
                     /locus_tag="RD486_001998"
     CDS             complement(11522..12229)
                     /locus_tag="RD486_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDT7663723.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12308..12646)
                     /locus_tag="RD486_001999"
     CDS             complement(12308..12646)
                     /locus_tag="RD486_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDT7663724.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12757..13719)
                     /locus_tag="RD486_002000"
     CDS             complement(12757..13719)
                     /locus_tag="RD486_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDT7663725.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKINVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13734..15065)
                     /locus_tag="RD486_002001"
     CDS             complement(13734..15065)
                     /locus_tag="RD486_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7663726.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15073..15753)
                     /locus_tag="RD486_002002"
     CDS             complement(15073..15753)
                     /locus_tag="RD486_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDT7663727.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15972..16451)
                     /locus_tag="RD486_002003"
     CDS             complement(15972..16451)
                     /locus_tag="RD486_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HDT7663728.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(16578..18257)
                     /locus_tag="RD486_002004"
     CDS             complement(16578..18257)
                     /locus_tag="RD486_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDT7663729.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            18805..20307
                     /locus_tag="RD486_002005"
     CDS             18805..20307
                     /locus_tag="RD486_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663730.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            20320..20982
                     /locus_tag="RD486_002006"
     CDS             20320..20982
                     /locus_tag="RD486_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663731.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(21083..21286)
                     /locus_tag="RD486_002007"
     CDS             complement(21083..21286)
                     /locus_tag="RD486_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDT7663732.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(21397..22581)
                     /gene="iadA"
                     /locus_tag="RD486_002008"
     CDS             complement(21397..22581)
                     /gene="iadA"
                     /locus_tag="RD486_002008"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDT7663733.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(22738..24477)
                     /gene="yfcC"
                     /locus_tag="RD486_002009"
     CDS             complement(22738..24477)
                     /gene="yfcC"
                     /locus_tag="RD486_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDT7663734.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(25249..25863)
                     /locus_tag="RD486_002010"
     CDS             complement(25249..25863)
                     /locus_tag="RD486_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7663735.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT         7728 a         5438 c         4370 g         8450 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcactatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttattccaaa taaatggtat
    11461 tcaatcagct aactctcggt attagctcag atcaaagcgc tgatttcaca acttctttat
    11521 tttaatctct tcggttgccg ccgaacaata agatcaagcg caacagctgc aggaatgtcg
    11581 aaagcgctgc tgcaacataa gtcagtgctg ctgcaaataa tacgtgtctt gccatcggta
    11641 cttcttcttc cgtcagtagt ccgccttcac tcaaaatttg gattgctcgc cgagacgcgt
    11701 taaattcgac tggtaatgtc accaattgga aaagtaatgc taaagaaaaa gcgaaaatcc
    11761 cgatattgat taacgtagag ttccagctaa gcaatacacc taccataatc aaggggaacg
    11821 aaatcatcga accaaagtta gctgctggaa caagtgctgc acgaatcttc aatgggacat
    11881 aacccgaagc atcttgtacc gcatgtccgc attcatgagc tgctacacct atcgcagcaa
    11941 ctgaagtaga ctgtgcagtt gcttgagaca aactcaacat cttattacct gaattgtagt
    12001 tatctgtgag atctccggca atttgttgaa caccgacatt atttatctgt tgactttgta
    12061 atatatattg tgctgcttgt gtaccagtca cattgttttt gcttctcact tgatcgtatt
    12121 ttcggaaagt actattgacg tacgctgacg caattccgga aataactaat ccaagaatga
    12181 ccaaaagaaa tgtcggatct aaaaaaccat acattccata accatacatt ttcgtttcac
    12241 tccttttcgt ttactttatt ttatcattag tagtaggaaa agaatgtgaa aagaccttga
    12301 atattcttta attctttttc acaaattccg atttcagttt catcggtcca aatccttcta
    12361 ccttgcaatc gatattatga tcgccttcta ctaaacggat gttcttgact tttgttcctt
    12421 gtttaatggc acctgacgca ccttttactt tcaagtcttt aatcactgtc acgctatcgc
    12481 cctctaacag acggtttcca tttgcatcta ataccactaa tccgtcttct atgacagttt
    12541 cttgttcttc tttgttccat tcgttcccgc attctgggca aatcaacaag cctcgatctt
    12601 catatgtgta ctctgagcca cattctgggc aatttggtaa tgtcatcttc tttctccttt
    12661 aaaatcttta gtgagcacta ttgtaacgga aaaagaagat cttgaaaaga tacatttgtg
    12721 atttttacta caaaaggcac gttttcgaac gaagtatcat tctgtttttc tgctcttata
    12781 cgattggcat atatcttgga tctctttata gatttcctct acttctgcta aatcttttgc
    12841 attcgcacca cttgctaatg gatggcctcc tccatgatgg cgtttagcca attcattgat
    12901 gatcggcccc ttagaacgta aacgtacgcg gtaataccct gaaggctgct gaacaaaaat
    12961 cccccaagcc agcacttcgt caatcactcc aggaagtgaa acgatcgaag ctgtctctga
    13021 atcatcgatt ccatatttat caagaatttc ttgcggaagg attattcttc ctgcaccatt
    13081 ttcatccacc tggatatttt gataaagata accggaaagt ttagcgactt tcatcggcat
    13141 ttgttcaatc tctctgttca aagcacttgc atcaaatgga taatttctca atatcgaagc
    13201 aatctctaat gtacgggacg tcgtggaggg atacaaaaag cgccctgtat ctccgacgat
    13261 tcctgcataa agtaaccgtg cagccttaac gtttatcttt aaagattcag gaaacatcaa
    13321 agcaaattct gcaatcatct cactacagct acttgctttt gtatttaccc acacaagatc
    13381 tccataaggg tcatcattgg gatgatggtc gattttgatc agtttttctg ccaactgata
    13441 tctttgatca ctgattctgg gtgaattagc tgtatcagtc acgatgacta gcgctccttg
    13501 gtagaagaca tcttcaactt cttgcatttc tgctaaaaag cgaagccctt caatcgtttc
    13561 acctacttga cgtatttctt tttctgggaa actttcccgt aatagttcgg ctaatcctac
    13621 ttgtgatcct aatgcatcag gatcagggcg caaatgcctg tggataatga ttttatcgta
    13681 tttttttatt gtatctacta tttcttgctg tactgtcatt tcactcctgc tttctaagaa
    13741 cgttccatta cttgacaaac aacgattgct ttggaaacga tggtgttttc aataaacact
    13801 tcgatatcca gtttagcgga acgtctgccg atttccaata cacgtggacg aatgtctaat
    13861 tcgctttcca attggatcag ccgcaaataa tgtaggttca cttgttcaat caagatattt
    13921 cgtttttggt tcatcaccat tgttttttgt gcgacatcag aaatgatttc gctaagtacg
    13981 ccaaaagaaa tggttccaac gccattgacc atttgtggtg ctactacgaa tttgaactta
    14041 gggttttcca aacgatttcc ttcacggtca gtatcaatcg tatggatatt tccagatatc
    14101 tgatccgaaa tcgtatctgc aatctgcggt tgtcgctgga caagctgcat cgctttcatt
    14161 acatcttgcc gggtaatcaa gccttccaat gtcaagtcat cggaaacgac cggcatgact
    14221 tctagcccat cccagatcat ttgatggcta acagaggcaa tactcattgt tttctttaca
    14281 ctgattggtt ctttcgtcat cacccgatcg atgatctggt ttggcgattt ccctaaaaca
    14341 tcttttgccg taacaatccc catcaaacga tgatggcggt tgacgactgg aaaacgcgaa
    14401 tgctgcgttt cttctgacaa acgctgataa tcagaaatcg tatctgtctg ctgcaaataa
    14461 tgagtctttt cagctggcat atagatatca ctgacaagca tgatatcttt tttgatcaat
    14521 tggtcgctta acgctcggtt gatcatggtt gcgactgtaa atgtatcata agaggtgcgt
    14581 aagatcggca tttcaagatc atcagctagc tttgcaatct cagcagtcgt attgaatcct
    14641 cctgtgatca atactgcggc gccatcttcc aatgctaatt tttggacttc cgcccggttg
    14701 ccgacgatca ttagtgatcc tggcgtaata tagcgttcca tggcatgttt agtcatcgcg
    14761 ccgatgacga atttattcaa gaccttgtct aatcctgccg ccccgcctaa aacgtcccct
    14821 tcaatgatcc tgacgacctc gccaaatgtc aaacgttcaa tatgtttttt taatttgcgt
    14881 tcgatacgga tggtccctac tcgttgaatt gttgaaacta gtccgacatt ttctgcatct
    14941 ttgattgcac ggtacgctgt tccttcactg acattcaatt cttttgcgat gcttcttaca
    15001 gaaattcgat tgccaacagg taaactttca atatattcta aaatcaaatc atgttttgtc
    15061 gccattttct gcctacactt ccagcgtttc cgagacgctc attatttttc cttcactatc
    15121 ttccagtaac tctacaaaag attcgggatc ttgttcaatg acagggaaag tattgtaatg
    15181 gattggaact actttcttgg cacgaattgt ttgcgcagcc tttgctgcat cttctggccc
    15241 catcgtatag ttatcgccaa tcggcaagaa agcgacatca atatcgaatt cttctgcaag
    15301 caatcctaga tcactgaaat aagcagtatc ccctgcatga taaatcgttt ttccttctgc
    15361 ttgaataata attccgctag gctcgcccat atactgaacg ataccgtcta cttcatagct
    15421 tgaactatgc tgtgcatgta cgaattttac cacgccgaat ggaaacgcat gttttccacc
    15481 gatattcata ccgaatgaat ctactcctct gctgttcgca taatcagcaa tctcaacaat
    15541 actgataatt gtggcttgat tttcttttgc aataggaatc atatctccta tgtggtcact
    15601 atgaccatga gtaatcagca accaatctgt ctttacttct tctgcagtta agtctgtcaa
    15661 tggatttcct gtaataaacg ggtcaatcat cacgcgttgg ccattttcca tttcaattgt
    15721 taaacaggaa tgtccatgat acgtaatttt catattttac acctcgcgtt ttctctgtat
    15781 cttttttatt aaaaacgatt tcatcacttg cacatcaatg aaaaaatata gctgctaaat
    15841 atattttcat tggattgata gtacagtatg tacaaagcaa ttgtaacaga taatacagga
    15901 tgcaccaagt accaagcaga tataatctca agtttgaggt ctctgctctg cttagcttct
    15961 cttctcgtcc cttaactaat taaatcagcg taaataggat ggacgatctt ttctaaatcg
    16021 gctactttta tccgaaggct tctcccgatt tcaccgcttg acacaattac ttcttctttt
    16081 tcttttaaag aactgtctgc taaaaaacaa taatcaggat gtgcgagttt tattccaata
    16141 ggggtgtttg ctccgtgggg atatcctgta tgcattaata caaaatccat tccaggaaaa
    16201 ccaactttac gatctttcgt cacttgtctc gtttttttgt aatctaagtg atcgttcaaa
    16261 ggaatcaatg cgatgatcac cccagttttg tttcctttca ctacgagagt tttacatatc
    16321 aaagctggat caatccctct tttttgtagt tcttctgtga aagattcttc taccacatga
    16381 ctaaaatcaa gtggttgata gctgatcttt tgttcttcta aataacgttc gacttttgtt
    16441 tgactcatca ttgattcact ccctttattc tatcgtttat tataaagcga gggatgctgt
    16501 attcaaaaat tatttgtttt tcgcaaaaaa agagcaagac gagcactcta tagagaggtt
    16561 catcttactc tttttgttta ttttttattt cgacgttgag tagcttccat aatgactggc
    16621 aagatcactg ggcggcgttt tgtttgttca aataagtaac ggcctaattg atctcggatg
    16681 tcttgcttta atttgctcca ctcaaaatca ttgctttcta aatgtttctc aacgattgtt
    16741 tcaatcatat tgctgctttc tttcatcaga tcacggctag cttttacgta aacgaatccc
    16801 cgtgaagtaa tttgaggttt tgaaatgatt ttcttttctc gccgactgat agtgacaacc
    16861 gctacgaaaa tcccgtcttc tgacaagatt tttcgatcac gtaaaacaat gtttccgata
    16921 tcacctatgc ctaatccatc aatcattaca ttttctgcac ttgtagttcc tgcaacactc
    16981 atacgcttgt tcttatattc cagcacgtct ccgcgtccag taatatagat atttttgtat
    17041 ggcatcccta ctgcatgagc caaatctgca tgagcagcta attcacgata ctctccttga
    17101 actggcacaa aatatgttgg tttcatcaaa ttgatcatta attgcaagtc attaggattg
    17161 gcatggccag aaacgcgcat attctcagag atcaacttca ctgttccacc agctcgataa
    17221 atgatatctt ccgttttcgc cacgatggtt tccatcgcga tgcttggcgt agtagtgata
    17281 taaaccaaat ctccttcttc aatcttgaca ttacggtgtg taccgtttgc cattttttgc
    17341 agagacttga tgggttcacc cattcggcca gtttctaaaa tgatcagttc ttctggatca
    17401 tagtttttca tgtctttcaa cgtaacaagc agatcttcac ttggtaattg aagtttttct
    17461 aaacgcatcg ctgtgcgaat aattcgttcg aaatcttgac cagtcaagac aacttttcgt
    17521 tgtgcttttt ctgctgcatc caatacttgt tgcactcgtt gcaaattact tgctacacaa
    17581 gcgacgatga tacgcccttc ccaatatttg atcgtatcaa atacttcatc tgctatttgg
    17641 gcttcagaag ctacaggctg aggattttct gcatttgccg attcacttag taaggctaag
    17701 actccttctt tgccgatttc cgccaatcgt gcataatctg tttgatacat tgggatagcc
    17761 gtttggtcaa atttaaaatc tcccgtataa acgatactac cttcttttgt tttcagattg
    17821 atccccactg aatctggtat cgtatgagtg gtacggaaaa agctcactac tgtttcacca
    17881 aagtctattt ctgtatgctc atctaccaca tggaaatcct taaatccttt ggctgcttca
    17941 ttacgactga cattcaattt tgctaactcg atcgtcaact ctgtcccgaa tactggtaca
    18001 gaaatttttg acaacaagta aggaagtgcc ccgatcgcat ctgcatgtcc atgtgttaaa
    18061 aagacaccag ctacacgatc aatgttttct tctaaatacg taaaatcagg gattacgacg
    18121 tcgatcccca acaactcatt ttcaggatat tttagcccac aatctaaaat aaaaatatcc
    18181 tcgcccactt ctgcgacata catgtttttt ccattttcac gaacgccgcc taatgggata
    18241 attttaatgg tactcacaaa cttcacctct tcttatgaca tccaagttta aagatgtcga
    18301 ttttcttctt tatctaaata tatgagccat tccaatgaag catatgcaaa atcactattt
    18361 ctcaacttat ggagaatcag caggaaaatt accagcacat ccgcgttctg acagttggat
    18421 gggcatttta ttttggatat acttcattaa caaaatggat cttttgcgaa acgctatagc
    18481 cagaatactt atataagtat tcagctgttc cccattatta tacaacaaat aaactaaatc
    18541 gctagtatca gcaattgtta gaacaactat gcacgtaaaa atccctctgt agcatctagg
    18601 atttcttttg ctattcctct ttcatttctt cttcgtcggt ttgaaacata cttttttcat
    18661 tttaccacat tttttgcaat aactatagtg actttttata tatacagaac ctcatgttga
    18721 tggtgtgcaa acagcataag atttaagcta gctttaagat aggttgtcta ttatcaaatg
    18781 catctactag gagggatgca aaatatgaat tttatgaaac gtgcatggaa aagtacaaaa
    18841 gtaaaatggg gacgttcatt gttattgttt gccgtgttca cagccattct tatttttgtg
    18901 ctagctggcc tcacgattcg aagcgctgca gaagaagcag cgaatcaagc acaaaaagaa
    18961 gttggagcaa cagtgacttt aagtgccaat cgagaagctt catttaaaaa acaggaacaa
    19021 acttcttcaa gcggttctac cactgaagaa cgtccagatc caggcagttt ttctcttaca
    19081 ccagtttcct taacggacgc ggaaaaaata gctgaattag ataatgtaaa gagttattcc
    19141 tttgaaagtt ccgcctcagc tatggcaaaa gatggaataa ctgccatcac tagttctgat
    19201 tcaagtgaag acagttcaga aactactgat gcaggcggtg aacctgctgg aggaatgggc
    19261 gggaatccgc aaatgactca agcagacttt caaatcagtg gtgtgtcagc aactgcacaa
    19321 aatagtaatt tttctgatgg aacagcaaaa atcacggatg gtgaaggaat agatgacagc
    19381 gacaaaggca caaacaatgt agtcattgat tctactctag cagaaacaaa tgacctggca
    19441 gtcggagata ctttcacaat cacgagtact gaagatgaag ataccactta tgaaatgacg
    19501 atcaaaggaa tttatgaatc cagcgaaaca agcggcagta tgggtatgaa attcaacttc
    19561 atgaatccgt cgaatacact ttacacttct tacacttttg caaatgaact aaatgggaca
    19621 tctgacgata acacgataga ttctgctatt tacactctat ctgatccaga taaaatggat
    19681 gagtttctca aagaagctga gaagctgatc gacacagata catttagctt acaatcaaat
    19741 gattccatgt atcagtcaat gttggaacct ttaaacaacg tggcaagttt ttctaaaaat
    19801 gttgttttac tagtggctgt agccggtatt atcatactta ctctgatcat tatgattacc
    19861 attcgggagc gtcggcatga gttaggcgtc ttgctatctt taggagaatc cagaagtaaa
    19921 atcattctcc aattgtttac cgaagtggct atttgtatga ttcttgcatt aggagttgct
    19981 tcgcttagcg gaaacgtcgt cgcgaatgcc gtgggacagc agctacttga ccaacagaca
    20041 gaaaccacga cacaaaacca gcaagctcct ggcggtggac aaatgccagg taacagacaa
    20101 gaacaaggcg gtcaacgcga tggtcaacaa ggaaccacga ataatccatt tgctgtttct
    20161 gatcaagtca gcgaattgga aatcaatgtc aaacctgcac aattgggact attagccgga
    20221 gtagcatttg gaatcagtct gttttctgtc tttttagctt ctatagggat attaagatta
    20281 aacccaagaa aaatcctatt aaactaaagg aggaatttga tgttacggac agaacaattg
    20341 ggattttggt atcaagatcc gcaagatgcg ctttataaag atgtagaact gaatttcgaa
    20401 gctggaaaaa tgtacgctat tttaggagca agtggttctg gaaaaacgac ttttctttcg
    20461 cttatttctg gactagatgc accaaaagaa ggaaaggtat actatcaaga tcgttcactg
    20521 aacaaaatcg ggttaagaag ttatcgtaaa aatgatgtct cgattatttt ccaagcttac
    20581 aacttgcttc cttatttatc ggctctagac aacgtcatag cagcaatgga aatcactaag
    20641 accaagcaag agaattatcg acaagttgct ttagatcgac tggctcgtgt aggaattgat
    20701 gaaatattag caaaaaaaca ggtgaccaaa ctttcgggag gtcagcagca gcgagtcgct
    20761 atcgttcgtg ctatctgctg tgaacatcaa ctaatcgtag cggatgagcc tactggaaat
    20821 ctagatgaaa caacttcaca agatatcgtc aaacttttcc aagaaatcgc ccatgaacaa
    20881 aatcgctgta ttatcatcgt gactcatgag attgaagtag caaaaagctg tgatgaagtc
    20941 tttgaactaa aaaataaaaa atttcaaaaa atcgaagttt aaaaaacagg ataatgatca
    21001 aataaaaaat ccgaaccata tctgtctcgc agatatggtt tggatttttt atttgcttga
    21061 ttcaattagt aataagtggt ttttattttt tttcgtcttt tcgagaaaac ttgtctttga
    21121 cttcgtcgcc taaatttcga gctttttctt tgatgtcagc acctagtgat tgtgctttcc
    21181 cttctgtttc tttgctcttg tcgtctgttg ctttgccgta tgcttctttt ccttcaccga
    21241 ctactttatc tttcatatct ttagaacgtc cttttaaatc tgccattgtg cttcctcctc
    21301 ttagtttgtt tattgatcta ccttcagggt aacatcaaca acagatacag acaaacagaa
    21361 cgctcgtttt ctaaaaaaga tagttagagc tgttgattaa aaactttttt cgaaagtccc
    21421 ccatactttg acttcttttt cttggaccat tatttctcct ttagcgataa ctgtatcaat
    21481 atcaagcgtt tctttatcca agatacacag atctgcatca gcaccaattt cgatttttcc
    21541 ttttttatcc aatttcaata tacgtgctgg attactggtt atagctcgta aggcgatttc
    21601 caaagggata ctttcttttt gcacagcttc tttgatccct actagcaatg ccttggcact
    21661 tcctactcct aaccctagga aatgattgtt ttcatcaaaa taaggcaagc ttccttgtcc
    21721 atctgaggtc atcgtgaaat tatctaaaga aacatcttcc tcgatcaatc gtttcagtgc
    21781 tttgctgaag cgaacttcac catctgtctt ctcccaaaaa tcaggatctt cgctagcagt
    21841 gaagtcaatc gtgccaccac gtttggcaaa tgccacgcaa gcttcaaata attctggtgt
    21901 gcgatttgca tgagtaggca aaaattgtgt gatcggaatt tctgtttctt ctacgattcg
    21961 tgtcaatagc tctagctttc tttttcctcc gcctaagtgg acattgatga tcccagcttt
    22021 tcccgataac atgcctccta cacgagcatc tgctactgca cgagcgaact cttcaaaact
    22081 tggctgagaa gaacggtgat cggatactgc gatttctccg attccgataa ttttatcaat
    22141 tgtcaaaaag tctttgatga tagaatctgt tactgttttt accggcaatc ggtacgaacc
    22201 ttcgtataca taagtggaga ttccttctgc ttccagacct ttcgctttgc tgatcaacgc
    22261 agtcatatct ctaccttctc cgtctgttcc caaacaaccg acaactgtcg ttacaccagc
    22321 tgtagtcaat tggctcaatg tgacttctgg cgttcgattt tgataaccgc cttctcctcc
    22381 tccacctaaa atatggaaat gacagtcaat gaaacccggg gttagtactt ttccctcacc
    22441 tgaaagttct tctacttcca ctccttcgta gccgccttct agctgttctt ctacagccaa
    22501 aatcttccca ccggcaatca gtacatccat ttttcctaag taatctggtg caaacacttc
    22561 aatttgtcga atgattttca tacatttttc ctctttcttt aagtataact gatgatagga
    22621 tcttaaaaaa taatccaaac gataggatct ttactccttt gattttaccg taaaatgacg
    22681 gttcttggag tccttatcta ctgtttggat tactttttta tttacaggtc tccagtacta
    22741 ctgcagacct attgcaatgg caatcatgat gaaaatagtt cctaaaacaa acaggaatcc
    22801 ttgcatcttg atttggaatc ttgcccattt tgcccattcg atccgtgcaa cacctagcac
    22861 accaatcaag ctggctgata cgggtgtaaa agcgtccata aaacctgaac caagctgata
    22921 agcaagaact gctacttgtc tggatacacc tactaaatct gccagtggag ccatgattgg
    22981 catagtcaaa gctgcttgtc ctgaatttga tgtaacaacc aagttgaaca aactttggaa
    23041 gatgtacatc gcccaagcac caatgacagc tggaacaccg gtcaacgccg tcccgatccc
    23101 atgcaaaatc gtattcaaag ctgaaggaac agatgcatca gatcctccca agacaagaag
    23161 aatccctttg gccataccta ctacgattgc tgtaccagct aaatcagctg caccagattg
    23221 gaaagaagaa gcgatgtcat tgactttcat tccatctaat ttgaaaagaa cagcaatgat
    23281 tccagcaact aatcccatca caaagaattg agaagcgatt tctggaatgt aatagccttt
    23341 ttgagtcacg ccccaaacga tccagacaag gacaactaac atctctaata agatcaattt
    23401 atgcccaagc atgaattttt tattttcatc agatgtcttt ttgatatgag aacggaaata
    23461 atcatctgat ttgtaagtca acgaactttc tggtttttta cggatttttt ctgcatatat
    23521 catcatataa ccagcggcta atgcagtaac aactacccac ataatcaatc ggaatgtcgc
    23581 accagacaac acggggattc cagcaatccc ttgagccacc gctacgctaa acgggctcat
    23641 ccaagaggtc gcatttccga cttgagatgc gacataagtc acggttactg ctacgatcga
    23701 gtcatatcct aacgcaatga caaatggaac catcaccatt gagaatggaa ttacctcttc
    23761 tgccatcccg aatgtagcgc caccgaatga aaaagcaaag aataatagcg gtaaagctaa
    23821 acgctccagt cccttagttt tactgataaa cgcatagata cctgcgtcga tcgctccggt
    23881 acgcataata ataccaaaag cacctccaac aacaaggatc aatgcagcga tccctacagc
    23941 agatccatac ttatctccag atactagtcc ttcaaaaaca aaatttaaga aaccaaagcc
    24001 gccaaaatca tctgttcccc atattttggc tgttttatgc aattttttag aagtatcata
    24061 gatattttcg ccgtactgat cgtaaagcac atcatctgtc aaggagattt catctagttt
    24121 ttcctgcgta agattttttt ctccgtcagc aatgactttt tccaatcctt tttccggaac
    24181 atccagtttt tcacgttctg ctggatgatc ttgcagttct tctaattgat caaacacata
    24241 cgacttatcc agctcgtaag cataacggaa ggaatcttga cgtaaaacag tacgagtact
    24301 tgtttcgcca tttgcatctt tgtattcaat atcttgcgtg ctgaactttc ctgctggaac
    24361 gacaaaagtc agtatccatg caaagatgac tacaccaaaa ataatgacat acgtatgggg
    24421 tgtcgataat ttagtgaagt cgcgtttcgg ttttcctgaa gaatttgttt tcttcaaatt
    24481 tatttcttcc tttctttttt cagtaatttt gatgaataaa aaatggataa tcaaatgaat
    24541 tatacagtaa aaatgacatt tccacatgaa taatttatta gaaaatcact tttttctatt
    24601 ttgttttttt ctcctatgta tgattatttt tttctctttc catttatatt aagtatttta
    24661 tttctctgtt tttccttaaa attctttttt tatttttaga ttagagaaaa tctcgtcctg
    24721 tttttttcat tttacaatca ttgaaaaatt gaatttcatt gcaaaaaaaa taataaacac
    24781 ttataaatat ccattatcta tccttcaatt tttgtgtatt ttatttctat tagaaaaagg
    24841 tatcctgttg gacaattttg ttatatcagg taaacttcat tgcaataatg ataacaaatg
    24901 tactataatt actttgtaaa gagttttggg gaagactctt tcatcaacgt gtattaagag
    24961 acaagaaaga atccatatgg attctttctt gtctcttttt ccactacttt ttatttttct
    25021 gacactacat attcttataa ctcatttctc ataactgtga aacaacttat aaaaataaca
    25081 aactttaaac aaaacaagct taaaatcaaa gatgatccat cttaaaataa ctaaaacaaa
    25141 aaaagtagtc gttgttaatc ctcattaata atcgttttct ttttttcaaa cgctccattt
    25201 ttatgtggaa cattattttt ttaaggaact ttgtcaacat gtggataact attttccact
    25261 tgtgtcctgg actagctgtt ttgctgtaaa atacaaaact tgctgcagca aaaagatcgt
    25321 tgcaagagag gctgttccgc agatcgctgg atctagattt ggcaaagtca agactgcatc
    25381 atgtaaattg gcgtggttgt ccaaaaccaa atcagcaaat tcaaataatc gcaaaccact
    25441 gctatgttgc gatttgatac ttcgtgacaa atcaaatcca gtaacaatga ttaatggatg
    25501 accattttct ttgatccact gagctagttc gatgattgcc gggtttcttc cttcattcga
    25561 aagaagaaga aaaatgtctt ctgatttgac agaaagctga tcaataattg cctgtcctgc
    25621 accttctagc gtttcataga cacctccggc tggattttca atcaatatac ttggtacaag
    25681 atccggggtt tgatcccaaa attcaaatgc tacaccactt agtgtgcggc tagcatatat
    25741 ctgcaatcta ccaccttgat taatttgttt cgcgatccaa gtgccagctt gaagcatcag
    25801 cggctcttct atccttaatt tctcttccaa ttggtgataa tagtcaaaat aacataaact
    25861 catttatctc tcccgcctag ctatacttga catgaataga aacagctgcc taatctaagg
    25921 aagtacataa aaaaacagta gttagacagt aacacatgtg gtctttgctg tttcaaacac
    25981 aaaaaa
//
LOCUS       DAPBBV010000038        25818 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.038, whole genome shotgun sequence.
ACCESSION   DAPBBV010000038 DAPBBV010000000
VERSION     DAPBBV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.038"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            163..849
                     /gene="gpmA"
                     /locus_tag="RD486_002011"
     CDS             163..849
                     /gene="gpmA"
                     /locus_tag="RD486_002011"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDT7663736.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(1147..1854)
                     /gene="deoD"
                     /locus_tag="RD486_002012"
     CDS             complement(1147..1854)
                     /gene="deoD"
                     /locus_tag="RD486_002012"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7663737.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(1871..2689)
                     /locus_tag="RD486_002013"
     CDS             complement(1871..2689)
                     /locus_tag="RD486_002013"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7663738.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            complement(2713..3879)
                     /gene="deoB"
                     /locus_tag="RD486_002014"
     CDS             complement(2713..3879)
                     /gene="deoB"
                     /locus_tag="RD486_002014"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDT7663739.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            complement(3978..4934)
                     /locus_tag="RD486_002015"
     CDS             complement(3978..4934)
                     /locus_tag="RD486_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663740.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            complement(4934..6067)
                     /locus_tag="RD486_002016"
     CDS             complement(4934..6067)
                     /locus_tag="RD486_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663741.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            complement(6060..7622)
                     /locus_tag="RD486_002017"
     CDS             complement(6060..7622)
                     /locus_tag="RD486_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663742.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            complement(7834..8916)
                     /locus_tag="RD486_002018"
     CDS             complement(7834..8916)
                     /locus_tag="RD486_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7663743.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            complement(8982..9380)
                     /locus_tag="RD486_002019"
     CDS             complement(8982..9380)
                     /locus_tag="RD486_002019"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDT7663744.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            complement(9401..10063)
                     /gene="deoC"
                     /locus_tag="RD486_002020"
     CDS             complement(9401..10063)
                     /gene="deoC"
                     /locus_tag="RD486_002020"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDT7663745.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            complement(10109..11410)
                     /locus_tag="RD486_002021"
     CDS             complement(10109..11410)
                     /locus_tag="RD486_002021"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDT7663746.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            complement(11551..12567)
                     /locus_tag="RD486_002022"
     CDS             complement(11551..12567)
                     /locus_tag="RD486_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7663747.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            complement(12875..13480)
                     /locus_tag="RD486_002023"
     CDS             complement(12875..13480)
                     /locus_tag="RD486_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7663748.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            13676..14599
                     /locus_tag="RD486_002024"
     CDS             13676..14599
                     /locus_tag="RD486_002024"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDT7663749.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            14658..16223
                     /gene="guaA"
                     /locus_tag="RD486_002025"
     CDS             14658..16223
                     /gene="guaA"
                     /locus_tag="RD486_002025"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDT7663750.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(16714..18345)
                     /locus_tag="RD486_002026"
     CDS             complement(16714..18345)
                     /locus_tag="RD486_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HDT7663751.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(18359..20032)
                     /locus_tag="RD486_002027"
     CDS             complement(18359..20032)
                     /locus_tag="RD486_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HDT7663752.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            complement(20045..20362)
                     /locus_tag="RD486_002028"
     CDS             complement(20045..20362)
                     /locus_tag="RD486_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7663753.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            complement(20387..21787)
                     /gene="lacG"
                     /locus_tag="RD486_002029"
     CDS             complement(20387..21787)
                     /gene="lacG"
                     /locus_tag="RD486_002029"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HDT7663754.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            22024..22809
                     /locus_tag="RD486_002030"
     CDS             22024..22809
                     /locus_tag="RD486_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7663755.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            22812..23504
                     /locus_tag="RD486_002031"
     CDS             22812..23504
                     /locus_tag="RD486_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7663756.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(23778..24149)
                     /locus_tag="RD486_002032"
     CDS             complement(23778..24149)
                     /locus_tag="RD486_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HDT7663757.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            24482..25669
                     /locus_tag="RD486_002033"
     CDS             24482..25669
                     /locus_tag="RD486_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HDT7663758.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT         7534 a         5670 c         4707 g         7907 t
ORIGIN      
        1 acgaacagtt gcgtgggcac tgttcgtttt tttatattct ctacttgttt tctcatagaa
       61 tcttatctaa tttttcgatg gaaatctctt ccaaaaaatt gtacaataaa acagaactga
      121 aaatttcaga aatataaacc tatcttaaaa ggagagctaa acatgccaaa attagttttt
      181 tctcgtcacg gtcttagtga atggaatgca ttgaaccaat ttactggttg ggctgatgta
      241 aatctagcac cagaaggaat cgaagaagca aaagaaggcg gacgcaaaat caaagaagct
      301 ggaatcgaat ttgatgttgc ttacacttct gttttaactc gtgcaatcaa aacatgtaac
      361 ttgatcttag aatattcaga tcaactttgg gtaccacaaa tcaaatcatg gcgcttaaac
      421 gaacgtcact atggtaaatt acaaggtttg aacaaaaaag aaacagctga aaaatacggc
      481 gacgaacaag tgcacatctg gcgtcgttct tacgatactc ttcctccatt aatggaagaa
      541 actgacgaag gttctgcagc aaatgaccgt cgttacgcaa tgttagacaa acgcgatatt
      601 cctggtggag aaaacttgaa agtgacatta gaacgcgctt tgccattctg gcaagatgaa
      661 attgctccag cattactaga caacaaaact gttttagtag ctgcacatgg taactcatta
      721 cgcgccctag ctaaacatat cgaaggtatc tctgacgaag acatcatgga tcttgaaatt
      781 ccaacaggtc aaccacttgt ttatgaatta aatgatgact taacagttgc taaaaaatac
      841 tacctataaa aaacactata aaaaagggac tgtgacacga tttgtcacag tccctttttt
      901 cgtataaacg gttttctcct gccaacttct cggtcacaag tcacaatatt catcaaacat
      961 gaaaagctgt tttttgaaat tgttccttgt gactcagagt taaacggcag attcacaacc
     1021 tcttggtaaa cggtgttcaa aagcttacat ttgcaataat aagtccagcc aagtcaaaaa
     1081 catgaggagc tatttttgct tggatgttct tattacttaa tgcagggcag ctttttcatt
     1141 tccttcttat tctgctatcg ctgtttccaa tcctacttcg atcatttcat tgaacgtaga
     1201 ttgacgttct gcagctgttg tttcttcacc ggtgatcaaa tggtcgctaa cggtcatcaa
     1261 acttaatgtc tgcacatggt atttcgcgcc taagtaataa agagccgctg cttccatttc
     1321 cactcctaaa acgccaagtt cagctaattg gaacgtctct gtcaaatcat ctttgtagaa
     1381 agaatcttcc gaaagaacat ttcctacatg aaccgtatag cccttttctt tagctatctc
     1441 atatgctttc agtaatagat tgaaatcact gattggagga aaatgaaagg cttggaaatt
     1501 tttttcgatc atcgaagaac tggtcgctgc accttgtgct agtactaaat cacgaacatg
     1561 gacgtctttt gacaatgcac cgcatgtacc tactcgaatc aatttcttta caccatacga
     1621 ctggatcaat tcatgggcat agatggtggc tgatggcatt cccattcctg ttccttgaac
     1681 agaaatacgt tctcctttat atttgccggt aaagcctaac ataccgcgta cctgattgta
     1741 acaaactgga tcttccaaaa aagtctccgc aatatattta gctcgcaaag gatctcccgg
     1801 aagtaaaatc ttatcggcga tctcgccttc tttcgcttca atatgcacac tcattttatt
     1861 gttcctccta ttacaataat gtcaatgttt ctttaaccaa tgctttaaaa gattgtttga
     1921 ctctctgagt tgtttctaca acttcttcat ggctcagatt cgcttgcata cctgctgcta
     1981 agttggtaat acaagagatt cctaacactt ttaatccgct gtgagctgct acgatgactt
     2041 ctggaacagt cgacatccct actgcatcgg ctcctattgt ccgagacatt cggatctccg
     2101 caggcgtttc ataagttggt ccagaatagc ccatatatac gccttcttta agatccaaac
     2161 ctagtttttc tgctgctgct tttgctgttg cttgatagtc aggcgtataa gcttgactca
     2221 tatctggaaa tctagggccc attgcatctt cattcggacc gatcaaagga ttttcaccag
     2281 taaaattgat atgatcggta atcagcatca aatctcctgg tacaaatgat tcgttgacac
     2341 caccacatgc attagtcaca atgactgaat gggcccctag tccggccatc acacgtactg
     2401 gataggtcac tgtttgcatg gaatgacctt catagtagtg gaatctccct tgcatggcta
     2461 acactttctt gcctgccaga gacccataaa ctagctttcc tgcatgccca actactgtcg
     2521 aaacaggaaa gaacgggatc tcatcataag aaatcattac agcatcttcg atttcatctg
     2581 ctaattcacc taatcctgaa cctagaatca aaccaaaatc aatttctttt actcctttat
     2641 caaggataaa ctgggtcgtt tcttgtaaca tctcgcttaa cttggtcatt tgctttctcc
     2701 tatttaaaaa gattatttta ataatttcaa gaagctttcg ccattttcag tcgaagaaac
     2761 actaaagttc tcagcaatcg ttgctgaaat atctgaataa tatccttgag gcaatgcccc
     2821 ttgttctttc atttttttac tgtaaaccaa taacggtaca tattctcgcg tatgatcggt
     2881 accagtaaac gtcggatcgt ttccgtgatc ggctgtaatc attagcaagt cgtcttcttc
     2941 catcgcttca agcaattctg gaattcgtaa gtcaaattct tcaatcgcat gcgcatagcc
     3001 gactacatcc cgacgatgac cgtataatgc atcaaaatct actaaattgg taaagctgat
     3061 tcctgaaaaa tcgtttttca taactttcag cagctggtca acgccatcca tattgctttt
     3121 cgtgcggaca gattcagtga ttccttgtcc gttgaaaata tcgttgatct ttccaacagc
     3181 aatcacgtcc tttcctgctt ctttcaaaga atcaaggact gtgtgtccga atggattcaa
     3241 cgcataatca tggcgattgc ttgttcgtgt gaagtctcct ggttcaccca cgtacggacg
     3301 tgcaatgatt cggccaatca tatacggatc atcttttgtt atatcacgaa cgaattggca
     3361 aatccgatat aattcttcta aaggaatgat ttcttcatgt gccgcgatct gaaggacagg
     3421 atcggcagaa gtatatacaa ttaaatcgcc tgttttcatt tggtgttcac cgtaatcgtc
     3481 aataacagct gttccgctat aaggtttgtt acatacgact ttacggccag aaaattcttc
     3541 gatttgtttg atcagatcat cagggaatcc attaggaaac acacgaaatg gagttttgat
     3601 attcaatccc atgatttccc agtggcctgt catcgtatct ttccctacag aaacttcttc
     3661 taatttcgtc gcatagcctt gatgatcttt cactgattcc acaccttcaa gaggacggat
     3721 cgttcctaaa ccaagctgct ctaaatgtgg aacgttcaat cctgcttctt tcgcaatgtg
     3781 tcctaatgta tcagaaccaa catcaccgaa cttatcggca tctggtgctt ctccaattcc
     3841 tactgaatcc atgacgatca gatgtacgcg tttaaacatg attattcctt ctttcttttt
     3901 atttttattg cctttaaaac aaaaagggcg agacgaaaaa cacttcccgt aacccaccct
     3961 ttttattcgc taaaagatta ttttgatttg atatagttct tcccgtttgc ttttggacca
     4021 gaagctttcc ctaagaaaac aaccagcaca atgattgtca gcaaatatgg agcaatttgc
     4081 agcaatactg gcggaatcga agaaataact ggtaattgtg cgccaatgat actcaagctt
     4141 tgagcaaaac caaagaacaa tgaggcaccc attgccccta aaggattcca cttaccaaag
     4201 atcatagcag ccatggagat gaacccttgt ccaacgatcg taccagctga aaagttaccg
     4261 gaaatcgact gagcaaaaac agcaccgccc ataccgccta acaagccaga aatcagtacg
     4321 cctgaataac gcatagcata tacattgata cctaatgtgt cggcagcttg aggattttca
     4381 ccaactgaac ggaggcgcaa gccgaatttc gtcttgaaga tgatcaccca agctaggaca
     4441 gcaatcaaaa tagcacaata agcaggtaag aatgtatttt taaagaaaat tggtccaatg
     4501 accggaatat ctgctaatcc tgggaaagaa aaatacccca gattctgcgt gatgttatca
     4561 gtttgacctt taccatacca tgctttgatc aagaaaacac ctaaagcagg tgccatcaga
     4621 ttaattactg tcccgctgat aatatggtca gcacgcaaac tgactgttgc tactgcgtga
     4681 atcagagaaa ataggatacc tacgacgcca cccactaaaa tagcgatcca tggtgtcata
     4741 gaaccaagtg atggactcat cgtcaagttg aaaacgatgg aactaaaagc acccatgacc
     4801 atgattccct ctagccctac gtttacgatc ccgcttcgtt cagaaaaagt tccgcctagt
     4861 gacgttagaa ttagcggtgt tgaataaacc agtgtagaag taaggatcaa ggcaattaat
     4921 tcgatagtcg acattatagt tcgccccctt catggttttg attcgttggt ttcgattcta
     4981 ttgtcgcaac gatctcttct tgttttttcc cttggaagac tttagccatg acgaaacgaa
     5041 tcaggaagtt gatcccgaca aagaagataa tcaaagcaat cgatacattg acgatctcaa
     5101 acggaacacc tgctcctgtc tgcatgccaa gtccaccgat cttcaaaata ctgaacaaga
     5161 tcgctgataa aagaataccg attgctgatc cagaaccaag caaggaaaca gccattccgt
     5221 caaatccaat agatagcgaa gtcgtttgaa caaagaagtt ttgatacgtt cctaatcctt
     5281 caaccacacc gccaagccct gccaaagcgc cagaaatgac catcgacaaa acgatcgtac
     5341 gtttactact cattcctgca tactcagaag caaaaggatt caatccaaca gaacggattt
     5401 caaatcctaa agtcgttttc ttcatcagca gccaaacgaa aataagcgcg atgattgcta
     5461 aaaataatcc tgagtttacg cgagagccgc caaaagcttg tgttaaccat ggtaaccgca
     5521 gtgaggcatt ttgactgatc atattggaag agtccaaact tgagcgatag ctttcaggca
     5581 tcacttcatg taaagcaaat gtgcttacgt ataataagat atagttcatc atgattgtta
     5641 cgatcacttc acttgttcca aaaaatgctc gaagtaaacc tggaacagcc gctgccatcg
     5701 caccagctaa ggcacctaag atcacgcata acggaagcaa aacaactttt ggcagatctg
     5761 gaaacgcaag tgccacccag acactgacga tccacccgca aagtgcttgt ccagaaagcc
     5821 caatattgaa aaacccagct gagttagcta cagaaaaacc taatgctgta aaaatcaacg
     5881 gcgttgcttg ccttaacgtt tcacctatcc ctctttgcga accaagggct gcatctagca
     5941 tagaagaata accttggatg ggctgaaaac caaaagcagc catcaatatc gcgcctaaga
     6001 tcaatcctaa aacaactgaa agtacaggca ctaataaatt acggaatttt tcgctgcgat
     6061 cattcatgtg cgccagcccc cttttctaac tcttttcgtg cttcttctaa ggtatagccc
     6121 gccatcaata gacctaattc attttcagat gtttctttcg gatcaacgat accgacaatt
     6181 tctccttcat ggataacagc aatacgatcc gaaacattta aaatttcttc taattcgaaa
     6241 ctgatcagta acactgcttt gtatttgtcc ctttgttcga tcagacgttt atgaataaat
     6301 tcgatcgcac ctacatccag tccacgagtt ggatttgcaa caatcaacag atcaggatct
     6361 cggtcgactt cacgagcgat aattgctttt tgctgatttc cgcctgataa agcttttgcg
     6421 ggaacaagtt cattcgttgt tcgaacatca tattcttcga tcaattctct ggcatgttca
     6481 ttcattactg aataattcag catgccgttt ttactgtaag gtttttgatg ataggtttgt
     6541 agtgcgatat tttcagataa tgtcatatct aggactaacc cgtatttatg acggtcttct
     6601 ggcacgtgtc ctacaccatg ttcagtgatt tttcggggtt ttttattagt gatgtcttcc
     6661 ccttttagct tgatatgtcc gctttctgcc tttcgcaaac cagtcaaagc ttggatcaac
     6721 tccgactgcc cgtttccatc gattccagcg ataccaagta cttcgccagc acgaacctct
     6781 aagttcaagt ttttcacggc ttctaatcca cgattttctt tcaccactag attttcaata
     6841 gacaaaacga cttcttgagg cttcgcttct tttttcatcg ttttgaatga aaccgttctt
     6901 ccaaccatca tatcggctaa ttgttgtgag gttacgtctt taacgttgac tgtaccgatt
     6961 ccttttccac ggcggataac tgtacagcgg tcagctactg ctttgatttc atctaactta
     7021 tgcgtaatca aaatgatcga cttgccttct ttgactaatt ccttcatgat cacgattaat
     7081 tcatcaattt cttgaggggt caatacagct gtcggctcat caaaaatcag tacatctgct
     7141 cctcggtaaa gtgtttttaa aatttctacc cgttgttcca ttccaactga aatatcacga
     7201 acgtaagcat ctgggttgac tgacaatcca tactgttcag aaactttttg gatctctttt
     7261 cgtgcttttt tatggtcaag catccctgcg cgactaggct cgcttcccaa cacgatgttt
     7321 tctgttacag taaaggcatc aacaagcata aagtgctgat ggaccatccc aatccctaat
     7381 tggttggctt tggtcggact tgtgatcttt acttctttcc cacgcatcaa aattttccct
     7441 gatgtcggct ctaataatcc ggaaagcacg ttcatcaatg tagatttgcc agcaccgttt
     7501 tctccaagca acgcatgaat ttctcctgcc tttacttgta aattgatgtt gtcatttgcc
     7561 ttgaatgttc caaattcttt ggtaatattc tgcatttcta tgacaatatt ttcttgaacc
     7621 accttttttt cacatcctaa cgatttctat ctagggcaac gattgactaa gattcacgct
     7681 tagtgagcgt tcttcttttg aaacaaacat tacttcaggg agttgttccc ttatccaaac
     7741 tgtcacaagg cagcttggat aaatgaacaa ttcttgttct aatcaaacca tagccttgtc
     7801 aaacatgtgt ctaacaaggc tatagaaatg gttttagttt tcttcaggag tttctggaac
     7861 ttttacgtca cctgaaatga ttttttcttt tgcttcatca actgcttttt tcgcttcgtc
     7921 agaaagttgt ccttctgtta gaccaacacc gtcttctttc aatccataaa cagtgtgttc
     7981 gccgccaggg aatttaccgt ccgctgattt ttgtgccaaa tcttctacta ctgttccaac
     8041 tgctttcagt gtagatgtca atgtgaagtt tttcttttcg ccgtttaatg tgtattcgcc
     8101 ttcgtctgat tggtcgcggt caacaccgat aacccaaact tttttgtcgc ctgattcgtt
     8161 caatgatttt gcttcttgga atacaccgtt acctgtaccg cctgaagcat ggaagatgat
     8221 atctgcgttt tgtgcataca taccttgagc aattgaacgt cctttatctg gagcagagaa
     8281 gtcaccagca tattgattca atactttgat ttcttttcct aattctttcg cacctgcatc
     8341 aacaccggct ttgaatccag catcaaaacg atcgattact tcacctttta caccgccgat
     8401 aaagccgact acgtttgttt cagtcgtata agctgctgca acacctgcaa gataagaagc
     8461 ttcgttgtct ttgaaagttg cagatacaac gttatctaat ccatcgatga catcatcgat
     8521 aataacaaag ttcgtacctg tattgtttgt tgcttgttct tggatcgctg gttttagttt
     8581 ataaccaata ccaaaaatcg ttttgaatcc agcattcaat gcttggtcaa tatttgggat
     8641 gtaatctgat tcatttgaag attggaaata ttggaagcca tcatttcctc gtgaaagtcc
     8701 ttgatctttc ccccattttt ctagtccttc ccaagctgac tggttgaatg aacggtcgtc
     8761 tacaccacct gtgtctgtga tcaatgctgc agttgttgtg tctgatgagc ttttgccacc
     8821 ggatgaatca gtagagccgt tgttgccgca tgcacctaaa aataaccctg ctgctagtgc
     8881 gacagcacct aaaccaaata attttgcttt tttcatttct gtaaagcctc ctaaaataat
     8941 tgttttattt ttcaacagtc agctgactga atgaacatga gttatagatc tttttcagta
     9001 aatgcataag gcagcagtgc acgaacggtc gttgccttcg tcacaccatt gtctcctact
     9061 agcgtaaccg gcatatcagg ggaacagaat tctgccatta cttgtcgaca tgcaccacaa
     9121 ggagagatag gatcgggggt gtgccccgct acgactagat gcgtaaatgt tttttctcct
     9181 tcagatactg ctttgaaaaa agctgtgcgc tcggcacaat tcgttaatcc aaatgatgca
     9241 ttctcaatgt tgatgccttg ataaatcttg cctgattccg ttacgagaca agcgcctacc
     9301 ggaaaatggg aataaggaac ataggcttta tctaacgctt caatagctgt gttgatccat
     9361 tcttgtttga gttctgccat gagcttctcc tttgaaaaaa ttaatagcct tcaccagttg
     9421 aaccagatac gattgctact cctgcgcttg ttccgattct tgtagcacca gcttcgatca
     9481 ttgccattgc ttcttcttcg ttatggatac cgccggaagc tttgacaccc atttctggtc
     9541 ctacagtttc acgcatcaaa cggacatcct ctacctttgc tccgcctgtt gagaaaccag
     9601 ttgatgtttt gacaaaatca gcgcctgcag cttttgctat ttcgcaagct cggatgattt
     9661 cttctctatc taataacgat gtttcaataa taactttgac aagcgcacga tcttttgctg
     9721 cttcaacaac tgcttcgata tctttttgga cttgttgatc atcctttgat ttcaaagcac
     9781 cgatattgat gaccatatcg acttcatctg caccgttatt gatggcatct gttgtttcaa
     9841 atgcttttgt ctcgggtgtg tttgctccta gaggaaaccc gattactgta catacggcta
     9901 ctggctcacc ttgtaattgt tctttcgcta gcgcaaccca tgctggattg atgcagacag
     9961 aataaaaatg gtattttttt gcttcttcga taatttgcat cacagcttct ttagatgcgt
    10021 ctgctttcaa aatagtatgg tcgatcattc ggtttagttc catttctttt ccccttttct
    10081 ttaaaacggt aaagtccgct tttttccttt attctgtgat gatgtcatga atcaacgttg
    10141 gcttcattgc cgattcacca atttcaatat ttttatataa taattcaatg acagaagtga
    10201 tttcttcgtc gttactatag atcgtcaata gtgactcacc ttttgtcaca gtgtcaccaa
    10261 tttttttatg cagtttcaat ccaacagcgt gatcaatatc ttcttctttg gttttacgcc
    10321 cagcacctag catcattgca gcaattccta attcatttgc cacgattttt gacacaactc
    10381 cgctttgttt agcaggaagc tccattgtgt agcgtgcagt caaaattcgt tctggatgtt
    10441 ccacgatcgc tgggtctccc ccttgatttt ggatcatttc tttgaatttt gctaacgctt
    10501 tacctgattc cagagcttct tgaagcaacg ttcttgcttc atcggttgtc ttagctttgc
    10561 cagcaagaac aaccatttgg cttcctaagg cgtagcacat ttctactaga tcttctggac
    10621 catttccttg taatgtttcg attgcctcga caacttctag actatttccg atagcttcgc
    10681 caagaggttc tgacatatct gagataaccg ccactgtttc tcggttagcc agtttcccaa
    10741 tgctcgtcat ggtctttgcc agacgtcttg catcttcgat gttcttcatg aaagcaccgt
    10801 ctccagtggt cacatccaaa acgattgcat ctgctcctgc cgcgattttt ttactcataa
    10861 tcgaactggc aatcagcgga agagaatcaa cggtcgctgt gacgtcacgc aaggcataca
    10921 attttttgtc cgccggtgcc aagtttcctg attgaccaat taccgctact ttactttcat
    10981 taacaatgcg tacaaattct tcatccgaaa gctcgatctg aaatccggga attgcttcta
    11041 gcttgtctag tgtaccacct gtgtaaccta gaccgcgtcc agacatttta gccactgtca
    11101 ctccgacact agctactagg ggggctaaaa tcaatgtggt cgtgtcacca acgccacctg
    11161 tcgaatgctt atctaccttt attccttcaa gagaactcaa atcgatgaca tcaccagaat
    11221 tagcaatcgc caatgttaag ttcgtgattt cttcatttgt catgtcttga taaaaaattg
    11281 ccatcaataa tgcactgact tgataatctg gaatctttcc attcgtatag ttcgtgacga
    11341 tgtactcgat ttcctctttc gacagctcgt ttccatccct ctttttttca atcagatcca
    11401 ccattcgcat tgcctgatcc tccttgtctt cattcggtat tatacattat ttttaggaaa
    11461 ggtaaaccac tttagtaaac tggtttacta aaaataaaaa aagcactaac tagcctttgt
    11521 aaatgcttac ataagcaata taccgccgag ttagcccttt gtcaatactt ttacgctctc
    11581 acgaataatt aattttgttt cgaacacttt gttcggaact tttctttgag gaaattcgat
    11641 cgtatcgatc aggaaacgtg cagcataaaa tccaatatca aaacttggct gctgcactgt
    11701 cgtcaattgc ggaatcatgt attctgacag ctttaatcca tcgaatccta tgactgagat
    11761 atcttctggg atttttttgc ccaattcatc gatcgcctga tagcatccga tcgccatggc
    11821 atcattcccg caaaaaatag ccgtgatatc tttatgtttg agtaattttt ttgatgcagt
    11881 atatccacct tggacagtca actctccatg ttcaacaaat ttcccattaa aaggcaggcc
    11941 atgatctttc agcgcatgac gatatccgtt gaaacgttct tctaattgat agtatccagt
    12001 ggtttccttc agcatgccga tcttcgtatg gccattttca ataaacagcg aaacagcttg
    12061 ataggcgccc tcatattcct ttacgataag ccgtccgtta tcccgacgat tcaatccgcg
    12121 atcgattaaa atgattggca ttttttgata aaaaccgctg tctaatgcat atttctcagg
    12181 taaaatattt ggtgtggcca gcaagattcc gtccactgag cggtgggaaa gctcttgtaa
    12241 atacttgatc tcattttctt ggctatgacg agaattgcat aacatgatca catagcccaa
    12301 aggattcaaa tagctctcta caccttcgat cagtttggag aagaagaaat cagtgacatc
    12361 agggacgatc attccgatgg tctttgaatg tcgattgatc acatttgaag cgaaataatc
    12421 gggcttataa tgatgttcat tcacgatcga caacactttt tttcttgtct tatcactaaa
    12481 tctgcttcct ttgttattca aaatctgtga gacagttgtt actgatacgc ctgccatttc
    12541 tgcgatatct ctgatggtca gcttcatcct attggctccc ttctatctaa attccctatc
    12601 agtgtaccaa aacccccaag aaaagaatag agaaaaaagg aaagtatgtt ttttgataaa
    12661 aacctccttt atctaccgac ttggcagcct tctatacaag ttctgtatct tatttatttt
    12721 atcgtaaaaa acaacgactc tgttcctact atttcttttt gaagaaaaaa tagttctttg
    12781 tttttaaaaa cttctcaaca aaaaaagaac tgatacgtac ccgtacatgc acgcccagtt
    12841 ccactctttc gtcgctccac tatttttcag ctagttattc tttcacactt ttgatgatat
    12901 aatatccttt atcttttgtg acgatttctg cattaccaaa tgtttcttcc attttctttt
    12961 gcgcactcgg cgctccttgt ttcttctgga tcacaattgt cagtgtaccg cccttcttca
    13021 accgaggata tgcgcctgtc aaaatttcat gtacaacttt ttttccagca cggatcggcg
    13081 gattgcttac gatagctgca taggtttctt catgaactgc ttcatagata ttcgattgat
    13141 ggatatcaac atgttcgatt tggttacgct ttgcgtttcc ttgcgctaga cttaccgctc
    13201 gttcattaat gtcgaccatt tcaacaaacc gctgtgtcgc aaatgccaaa gctaacccaa
    13261 tcggtccata cccgcatccc acatctaaga tctttccttc atcaggtaac tcttcccaat
    13321 cgaaagcatc aatcaggaca cgtgaaccat aatccactgt ttcacgtgaa aatacaccag
    13381 aatctgttac aaattgaaag gttctgcctt ttaactcaaa agcccattgt tcaaaatcgt
    13441 gcgccgtatc tgggcgttca gaatagtaat gatttgtcat gtcttccatc cttctcattt
    13501 ctttcatgac aacagtctat ccttttatgt atccgtgcgc aagtcaagaa taagactccg
    13561 tttctttcta ttataaagat tatacaaaaa gatcggcaat ctctcttaag tggtggggtt
    13621 tgcgtttatt ttgtgttaaa atagttccat tgatgggaga acgcaggagg ctaatatgaa
    13681 tgatccaatg aactactacc gtgtggcaag agaagaatgg cgagaatttt atcgtaatgg
    13741 gcaagcacct ttgacacaag atgaactaga taatatcaaa agtttgaatg accgcatttc
    13801 catgcaggat gttcgagata tctatgtacc tcttgctcat ctgatttatc tttatatgaa
    13861 agaatttgaa tctttgttct tgagtaaagg tttatttctt cataaatacg tagaagtacc
    13921 gccttttatt atcgggatcg ccggaagtgt agccgttgga aaaagtacaa cagccagact
    13981 gctgcagacg attttgtctc gtaccttcaa acgaagaaac gttcagctga tcacgactga
    14041 cggatttctt tatccaaatc gtatattaaa agagcgtgga atcatggacc gtaaaggatt
    14101 tcctgaaagt tatgatatgg agatgctgat cgatttcttg aaccgtgtaa aatctggtca
    14161 ggaagagata aaagtacctg tttactcaca tgatgtgtat gatatcattc cagacaagta
    14221 cgaattgatc cagcagcctg atatcttgat cgttgagggg atcaatacgc ttcaattacc
    14281 tgcgaatcag caaatctacg tcagcgactt ttttgatttt tctgtctatg tcgatgccga
    14341 tcccgtgctg atcgaaaaat ggtatttgga tcgttttggt gcgttactgg atacggcttt
    14401 ccaaaatcca gagaattatt attatcgttt tgctatcgga gatcgtgaag aagcctttaa
    14461 aatggcaaaa gatgtatgga aaaatgtgaa tttgaaaaat ttacaggaat atatcttgcc
    14521 tacacgagga agagccgata taattctcca taaaactgaa aatcatatca tcgattcgat
    14581 tttcatgcga aaatattagc attttaaaat agtttgacta ttttgagata aaatttaaag
    14641 ggataggggt aataaatttg acaaacgttg ccgatatgac gaacgttgaa aagattatcg
    14701 tattagacta cggtagtcag tataaccaat tgatcacaag acgtattcgt gatcttggag
    14761 tcttttccga attattgagc caccgcatta ctgcagaaga agtaaaagcg atgaatccaa
    14821 agggaatcat tctttctggc ggaccaaaca gtgtatatga tgagaatgca tttgggatcg
    14881 atcctgagat cttcaattta ggtattcctg tattagggat ttgctatggt atgcaattga
    14941 tcacgtacaa acttggcggt tccgtagagc ctgctaaaaa ccgcgaatat gggaaagcct
    15001 tgttagaagt aacaagcgat caagctgtct tgtttaaaga aacaccaaaa caacaaacag
    15061 tatggatgag ccatggtgac ttggtaacta aagttcctga aggctttgaa acagtcggaa
    15121 caagcaaaga ttgtccgatt gcttctatcc aagacacaac acgtaatttt tatggtatcc
    15181 aattccatgc agaagtacgt cattccgaat acggaatcga attgctgcgc cactttgcct
    15241 ttgatgtttg tcactgtgaa ggtaactgga caatggataa ctttatcgat atgcaagtag
    15301 aaaaaatccg tgaacaagtt ggtgacaaaa aagtcttgct tggtctttca ggtggcgttg
    15361 attctagtgt cgttggggtt cttttacaaa aagcgatcgg tgaccaattg acatctatct
    15421 ttgttgacca cggtctgcta cgcaaaggcg aagcggaaca agtaatggaa agtctaggcg
    15481 gaaaattcgg cttgaacatc atcaaagtca atgcaagaga tcgcttctta gacaagttga
    15541 aaggtgtatc tgacccagaa caaaaacgta aaatcattgg gaatgaattc gtatatgttt
    15601 ttgatgacga agcaacaaaa cttgctggtg aagaaggcgt ctctttccta gcacaaggaa
    15661 cgttgtatac tgacgttatc gaatctggta cagaaacagc acagacgatc aaatctcacc
    15721 ataatgtagg tggactgcca gaagatatgc aatttgaatt gatcgaacca ttaaacacat
    15781 tattcaaaga cgaagtccgt gaattaggga ctcagttagg catgcctgat tcaatcgttt
    15841 ggcgtcagcc attccctggt cctggtcttg gtattcgtgt tcttggcgaa atcactgaag
    15901 acaagctaga aatcgtacgc gaatctgatg ctatcttgcg tgaagaaatc gcagctgctg
    15961 gacttgaccg tgatatctgg caatatttca ctgttcttcc agggatccgc tctgtcggtg
    16021 ttatgggtga cggacgtact tacgactaca cagtcggtat ccgtgctgta acttcaatcg
    16081 acggaatgac cgctgacttt gcccgtatcc catgggaagt cttgcaaaaa atctctgtac
    16141 gtatcgtaaa cgaagtagcc cacgtcaacc gtatcgtgta tgacatcact tctaaaccac
    16201 cagcaacagt ggagtgggaa taaagagcca acataatatg gagggggaat ccctataaat
    16261 caacattctt caatagctaa aatgcttgat tttcattaaa aataagatgg ttccctacca
    16321 aaagagacta taatataagt taatttgttt cattcttatc ataaaaagaa gttctcgaaa
    16381 aacgaactgt tttccgagaa cttttttcta tccatctaag tgctcaaatc atattcacga
    16441 cggaattcta aggttaccct ttcttaaaca aactttatgt tatctgcaca actttttgca
    16501 attttttcat tgcttcttac gaaatcgttg aactctcttt agcataatac aaagtgtaga
    16561 tgaagtctgg tgctttactc gttttggtaa aaatgactgg aaatcgtttc tggttatttt
    16621 tggcaaaggc gaggtgcagg ttcgattcct gccttctacg ctaacgatgt ggctgaaggg
    16681 aacctccgat cttgaatcga aacgatccgc agtctattgt ttcaccaatg aaacaaaatc
    16741 aacgttcgtc caagcatttc ctgaagcctt gctataaacc ccaatttcac aaacacctgt
    16801 tgtaattgga atgtctttga ttgtaatttt tgtccattca cttgttttaa caaccgcagt
    16861 atttagttcc gctccaccat aatttttgat atataactga ttagtatcaa actctccccc
    16921 agacattaca taggcactca atgtgtaagt tcctttgctt atgccactaa cattttgata
    16981 agctgatgcc tcgtatgctt gatcctgcca aaaagttagt ttgtagtccc caaaaaaagt
    17041 gcccgcttcc gttttgatcg tacccttagc ggttccttgt tgaaaccagg tttgccaatt
    17101 ggaaggactg gtcgttggtc catcgctttc gaaacttgca tttttaacta gatttatttg
    17161 cgcccctgct tgtttaaacg cacgcaagct tggcaaggcg tttccagcaa aatcaaacat
    17221 cgcttggttg tcccattcgt ttcccatagt ggattgaaca ctgagataat tcatacctgc
    17281 ttgtgttgcc caactcacat ttccgttgta ccaaagaggt tcccaataga agaagcccgc
    17341 cccgcgatta ttcggtactg cctgaatccg atcggcaaga tccagcaaat actctgcttg
    17401 tcctgtcggt gttggttcat atccccccgc agctgcttcg gcttcaccaa aagcatttgg
    17461 catagtatcg gcattcgctg ttgtatgccc ataagctgtt tcaactacga tcacttcttt
    17521 accataccgt tggctgatcg cattcatatt ggtttgaagt tcattcattg aaccgtgcca
    17581 atacggataa tacgacactc caattaaatc aaatgacaca cctcgactcg tgatttcatc
    17641 aaaccaccaa gtaaatgctc ctgtatcgcc accatcagct aagtggagca ttactggagt
    17701 tgttttaggt tgagtgtctc gaacagcttg gataccagac ttcaaaaaag cagccaatcg
    17761 atcaaattct cccccgcctt ctccccaaga cttgccataa ggccagagca ttccgctatt
    17821 cagttcattg ccgatctgaa ccatatcagg ataaacgtcc agctgcttca tttccgacag
    17881 aacgttcttt gtatagtcgt acaatgccgt attcatttct tcaaaggtca gaccttgcca
    17941 tgctttagga agattctgtt tcccaggatc aacccaaaaa tcactgtagt gaaaatccag
    18001 cagcacctta agtcccagat tttttgctcg ttttgcaagg tcaatcgtcg tttccagatc
    18061 atttgtccct gctccataac tttctccatt actattataa ggatcctgcc acaaacgcag
    18121 tcgaacatag ttgacaccat tattttttaa aatctctaag gcatcttttg aaatatcgtc
    18181 ttcataatat tttgcaccag atttttccat atctgacagg atcgaaatat ctgctccgcg
    18241 aataaattcg ctggcagatg cttcaacagt ttttgaaaca gcccccaaag cccctaacac
    18301 agctgcaaat aaaacagctt tacgcaacca aattcccatt ttcattatgg ctcctccttt
    18361 attgaaattg gttcagaata aactgaacag ctttttcagg atctctcgtt aatccgatat
    18421 attctgctcc ttttgtcgca accagcttga ttcctaagcg atcggtgtct tctttgatat
    18481 catcatagta agaattgact tgcggtgcta agaccaccat atcaaaatcc tgcagcattt
    18541 cgtaatgaga accataagca cccgccattg cactgatcgg tgctttcgat tcagatgcac
    18601 ctttttttaa agcattagct aacatcgcac ttgtccctgc gccagcacaa agtaccaaca
    18661 cattgatttc tttatttgca tcgctgataa cttgactcgc tgccacaggt acttcctcac
    18721 gtacatcggc agaagcacct tcctcggttg cgatcacctc tgctttttgt gcttctttct
    18781 ctactaagac agcatcgtat gctttgcaaa atggtagata gatcaggaag tcaacgacga
    18841 ttagaaccgc tgctagaaca aaagctaaga tacccatgcc cgttcctaga accaaaccga
    18901 tcggtgctgg agttgcccaa ggcaaaacgt acataaagct gttcatgccc aatacatcga
    18961 caaaaaactt gaacaggcaa acgtttacaa caggtgttaa caaaaatgga ataaaaaaat
    19021 aagggttcaa aatcatgggt gccgcaaata gcaatggttc gttgacagcg aaacttactg
    19081 gaataaagga agctttccca actgccttca actgcttaga cttagcaaag agtaggaaga
    19141 taaaaggaac aaccaatgtt gccccagttc ctcccatagt tcctacaaaa ttccctaaac
    19201 ccaccgtcag tactttagaa gcttgttcac cggaattgaa caattgcaga ttggtttcca
    19261 cattggcata gataattgcc gcaattgccg gctccacgat cgacggtcca tgaacaccga
    19321 caaaccaaaa cagcgccatc gctccccaga taatagcgat tcctaagtac ccgtcagctg
    19381 ctgtaaatag cggctgcagc accgtaatga ttgcttctgc aaatgagatt tggaagattt
    19441 gtcgaatgcc taaatcaatt aaaacggccg caaatactga aaaagagaaa ggaaaaatat
    19501 ctcggaaggt ttgcgaaatc gttccaggaa cttctttagg cattttaatg gtaatatctt
    19561 tcagcacaca aaacttatat aaattaactg ttaaaaatgc agcgacaaag gaagccagta
    19621 gtccctttgt ccccatatat tccgttgaaa atccaccttc aatcggagag acgcttaaca
    19681 acaggaaact taccacagag gccagcatca cagaggtggt gttgattact ttgtttttcg
    19741 gtaagcgacg attcatcgaa tcagccaagc agcgagcagt ggttgctgaa acgagtaacc
    19801 ctacaacacc catcgaataa ttatagactt tccatagcca tgtggagaca gattcaggcc
    19861 attggtaacc aaaaatctca ggaaccgcag caatcaaaat gaaaatgctt gaaaataaaa
    19921 tagctggcat cgctgttaaa aatccgtcac gaacggctcc taaataacta ttacgtgaga
    19981 ttttttcaaa aaatggtttc cctttttcga tttgtttaat gattccatcc atagcgttct
    20041 tctcctatcc ttgattctgt ctgtacagta caataaagtc ttgaatcaga tctctcagca
    20101 ataaagtggt cattaaatga tcctgcccat ggataaaaat gaatcccatc tccatctctt
    20161 tcccagatgc ttcttccgct aaaatttttg tttgcgaatt atgtgcaagg gttaaatttt
    20221 cgtcggcttc tttcaacgcc gaatcaacat gttcaaagtt tccttgtctt acttctttca
    20281 ataatttcaa taatgtactg cgagcgtcgc ctgaatatgc aacgatctca aaaccaagca
    20341 tttgtaattc ctctttattc atcttttctt cctccattat cacttattaa ataatcgttt
    20401 tggtttcact gaccaacttg taccagtaag ctgattcttt tgggtaacgc ttctgggttt
    20461 caaaatcaac ataaaacaag ccataccttt tgttataccc atttgtccat gagaaaagat
    20521 ccataagcga ccacaaaaaa taccccttca catttacccc ggctgttatc gccttgctta
    20581 aggattccaa atagactctc aaatagtcga ttctcggctg atccataata atgccatctt
    20641 caaactgatc tttatacccc atcccgttct cagtgatata gattttgttg taatgtgggt
    20701 aatcgctttt aattcgcagc aacaagtcat atagaccttc tggataaatc agccagtccc
    20761 aatcagttcg aggaattcct tctttataaa tacgttctcc gattcccttc actttataaa
    20821 cagaggtccc tttttcaccc gtaccgttat gatggattgc attttctcca tcgtaagctt
    20881 tgacaaaatg gcattggtag tgattgatcc ctaagtagtc attacgcgtg gatgcttttt
    20941 tcaattcaac gaaatcttct tcaggaaaat gatagctggc ctgatttgct tcacatatct
    21001 catcaagagc agtcaaggtt tcagttgaat aatagcctaa ataggtagca tctaataaga
    21061 aacggatcga caatgcatcg tctaaaaagg cagcatgctt atcttccggc gcgtctgttg
    21121 ccgcatattt cgtctctaat gagtgaacta caccaatttc acccggaagt tcgttttctt
    21181 tgaaatagtt cactacacgg gcatgagcaa ccatcatatt atgaagacag gcgacgatct
    21241 ttgtaaaatc atatttgatt cctggtggga aaacacctaa caaatattga ttggttgcaa
    21301 ctggatagat ttcattaaag gtactccaca ccttgacttc tttgaattca tgaaaacaaa
    21361 aaatggcata ggaaacaaat gcttctattg tttctcgatt caaaaaatct ccatggtcaa
    21421 acaaacgttt aggggtatca aaatgatgca acgtcacaaa cggcgttacg tttcttttct
    21481 tacattcttc gaacacacga tgataaaaag cgattccttc tggatttggt ttcccagctc
    21541 catcaggaaa aatgcggctc caagcaatgg ataatcttag accatttaca ccaaaacgtt
    21601 cacacaattc aatgtccttt gcatattgat gataaaaatc acttgccgga tcgggactga
    21661 atcgcccttg ttcctctaaa aagtcatccc aagcaacagc gcctttgcca ccttccttag
    21721 tggctccttc aacctgatag gctgctgtgg ctccgccaaa aataaaatct tctggtaatt
    21781 taagcatgta catctctcct caaatctata atcagttttc gctctttcta actgattgca
    21841 ttgtaaacgc atccaaaaca tttgtcaaca aaaacaaaca caaataatca taaaaaccag
    21901 aaaacagcaa taaaatctat tgtaacaaac ataaaaacca ccctaaatgt ttacttttgt
    21961 tcgaattaga ttgactgttg tccgtttata tgatagatta tccttaaatt agaggtgaag
    22021 acaatgttga aaaaagaaag attgcttact atcgtagaaa tggtcaataa aaaaggaatc
    22081 cttaccgtta atgaaatcat caatcaatta gatgtttctg atatgaccgt tcgcagagat
    22141 ttagatgaat tagaaaaatc gggcaagctg ctgcgtgtcc atggaggggc tcaaagtctt
    22201 tcctacactt tagatcaaga actttctcac actgaaaaag ccactctgca gattcaagaa
    22261 aaaaaagaaa ttgctgccac agcagcctcc ttgattcacg agggagaaac gattttctta
    22321 ggaccaggta caacaatcga actattggcg acgcatttac tgaacaagaa aattcggatc
    22381 attacaaata attatccagt ttttgatatt cttgctcaag cagatggacc agaaattcta
    22441 ctgattggcg gtgatttccg gaaaaatacc ggcgcatttg tcggaccgat caccaacgac
    22501 aatttaagaa gactaaagtt tacaaaagca tttatcagtt caaatggcgt tcacaacgaa
    22561 gcgatctcta cttacagtac cgaagaagga gaagcacagc agatcgctct aaataattcc
    22621 cgtaagaaat atctactcgt tgataataaa aaattcaatc gagatgattt ttatgtgttt
    22681 tataatttgc atgatttcga tctgctcatt acggatcgcc agatctcgcg ggaggttcaa
    22741 gagcactatg cacaatatgt cgatctgcaa attgctgatt caaccgaaaa taccactata
    22801 ggagcgtaac tatgaaaggg attatatttg atttcaacgg aacaatgttt ttggactctc
    22861 atctgcatga agctgcttgg ctgcatatga tacatgatca tacaaaagat ggtttatcag
    22921 acgaggatat tttaaaaaat attcatggtc ggacgaatac ggagattttg aaacatttca
    22981 tttcagagca tttgaccgcc tctgagatcg ccgtattgtc agaagaaaaa gaaagctatt
    23041 atcgtatgct ttgcttgcaa aatgaaaacg agcttcagtt gacaaaaggg cttgaagcga
    23101 ctcttgacca gctgactgac caacagattc cattaacgat tgccacggct actgtcaaag
    23161 agaatgttgc tttttatttt gatattttcg atttagcccg ctggtttgac tgggacaaga
    23221 ttgtctatga cgacggctct ttccctggga aaccgcaacc ggatattttt cttaaagcgg
    23281 cagacaaact gagcttagct ccggctgatt gtcttgttat cgaagatgct tactcaggat
    23341 tacttgctgc caaacgtgcg gggatcggaa caattattgc aattgatcca ttcggtaaaa
    23401 acaaaacagt atttgaacag gcacagctaa ataaagatgg aaccatcaaa gattttactg
    23461 gtttttggac agagcacctg tctgccacat ccgttaattc ttaaacgatt caactaacta
    23521 ccaaagaaaa gcaactgaaa tgcacacctc cttttataaa aaactgccag tgaaacgaca
    23581 tgaaagatac actgctatat ccttagtgaa atatagcagt gtatctttga ctttttcatt
    23641 cttttaacca tatgacgcgt tcatctctat ctataattaa cattaaaaat agtgttttca
    23701 cattatttct caaaccaatc ttaaaaatca tcaggagtac ttttttgata tacttttatt
    23761 aatgctgggc gtaatggtta aaagatttcc actagttcct ctccaccaag ctgagttgaa
    23821 aaatgcttat ctgtaaacaa catagacaaa gaggaaataa acgtttccgt atctttctct
    23881 gtcccaagga tattaattaa ttttcctact aggtaagtat cattaaactt aagatctgcc
    23941 ttcacatcaa aagttttgat aaaagctttt atcatgcgta caattttgtc tttatcgcca
    24001 taattgattt caccactcat atcaatatag tcactaatcc ctgaagaaat aatggcaact
    24061 gcttcttctt tcgccttatc agataattca tttaatgact gggattgatt gatgacttct
    24121 tgagttttat ctgttacgta atctctcatt atcctatcgg catactccgc aaagtaatct
    24181 tgaaaaaatt cttctacagg gtaaccaact tcgttttccc aaccaggaga aatttcatta
    24241 tcagtactta ttaaatctat taaaaaccaa cccgttctct gagtgttgat tctataatat
    24301 ttttaatttc ctatataaat caaaaatatt atagaatcaa taagctaatt aagaaacaaa
    24361 ctttagaaac tctgattacg tccatataat tgtgtaaaag tgaagcatca aaaaagccat
    24421 tgatctcagt taggagtaca atgttttttg cagaaaacat actcgaatag gactgatatc
    24481 aatgactcaa gtacatttta cttttgaaag cgaagaaatt caagcaatta taaacgaaag
    24541 cggtgcgaat gataccgcaa aaacacttat gactatcatg tttaatcagc tgatggaaga
    24601 acaacgaaat caatatattc aggcaaatgc ctatgaacgt tcagaagaac ggcaatcaca
    24661 aagaaatggt tactacgatc gttcgtttac aactcgaatt ggtacgttag aacttcatgt
    24721 tccacgaacc agagacggta agtttagtcc tactatcttt gaaagatatc agcgaagcga
    24781 aaaagctttg atcgctgcca tgattgaaat ggtcatttct ggtgtctcca ctcgcaaagt
    24841 aactaaaaca gttgaactgc taacggatgg tgcgactgtt tctaaatcat tcgtttcaaa
    24901 tctgatgaaa cagttggatc catttgtttt tgagtggaga aaccggagcc tagaaggctc
    24961 ggaatatcca tttttcatgt gtgatgccct gtatatgaaa gtaagggaaa atcatcgtat
    25021 tgtctcaaaa ggtgtatata ttggtatcgg cattgattct gatggacgac gtacgattct
    25081 tggttttgat gttcaagacg gcgaatcgga agataattgg gataccgttt ttcaatcgtt
    25141 cgttcaacga ggtttgttcg gtgtaaaact ggtcatttct gatgcacaca aagggttagt
    25201 taaggctgtt cgcaagaact ttttaggtgc gagctggcaa agatgccaag cccacttttt
    25261 gagaaatatt tttgataagc tgccaaagaa agtttcttct gatgtaaaag acgagttgaa
    25321 gagtatcttt aaagcctctg aacttgaatt gacacgtgaa agaaaagagc acttcttgga
    25381 aaaatatggt tgtgattcaa aattaagtgc tgcttgcgac attttagaaa acggctttga
    25441 agatgctatt caaattttgt cttttcctga aaatatccgc cgaaggattc gtacaaccaa
    25501 tgtgttggaa cggttgaacg aagagattcg ccggagagaa cgagtgattc ggatttttcc
    25561 aaatatcaat tccatcactc ggataattgg aacacttttg atggaaaaag acactgagtg
    25621 gctggcttct ccacgaaaat atttagaatt taattcgaat aacatttagc accatgaacc
    25681 tgtgcgagtc tcttctttct gaggagagac atcaagagtc gctgcgctac tgctcctgac
    25741 ctctctcctc agaaagaaag gcatggcagt taggttcaca acgcaaaaca ttgtgctttt
    25801 gatgaggttg aactttta
//
LOCUS       DAPBBV010000039        25784 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.039, whole genome shotgun sequence.
ACCESSION   DAPBBV010000039 DAPBBV010000000
VERSION     DAPBBV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.039"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(451..1761)
                     /locus_tag="RD486_002034"
     CDS             complement(451..1761)
                     /locus_tag="RD486_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDT7663759.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="RD486_002035"
     CDS             complement(1773..3191)
                     /locus_tag="RD486_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7663760.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="RD486_002036"
     CDS             complement(3431..4999)
                     /locus_tag="RD486_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDT7663761.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="RD486_002037"
     CDS             complement(5003..5413)
                     /locus_tag="RD486_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDT7663762.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="RD486_002038"
     CDS             complement(5410..6333)
                     /locus_tag="RD486_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HDT7663763.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="RD486_002039"
     CDS             complement(6330..7208)
                     /locus_tag="RD486_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HDT7663764.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="RD486_002040"
     CDS             complement(7195..8532)
                     /locus_tag="RD486_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDT7663765.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="RD486_002041"
     CDS             complement(8535..9638)
                     /locus_tag="RD486_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7663766.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="RD486_002042"
     CDS             complement(9712..11220)
                     /locus_tag="RD486_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7663767.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="RD486_002043"
     CDS             complement(11186..11878)
                     /locus_tag="RD486_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7663768.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="RD486_002044"
     CDS             complement(11900..12874)
                     /locus_tag="RD486_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7663769.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="RD486_002045"
     CDS             13174..14046
                     /locus_tag="RD486_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7663770.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="RD486_002046"
     CDS             complement(14504..16702)
                     /locus_tag="RD486_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663771.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="RD486_002047"
     CDS             16934..17926
                     /locus_tag="RD486_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7663772.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKTETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="RD486_002048"
     CDS             17986..19407
                     /locus_tag="RD486_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HDT7663773.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="RD486_002049"
     CDS             19400..20899
                     /locus_tag="RD486_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDT7663774.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="RD486_002050"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="RD486_002050"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDT7663775.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="RD486_002051"
     CDS             22491..23174
                     /locus_tag="RD486_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HDT7663776.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="RD486_002052"
     CDS             23176..24012
                     /locus_tag="RD486_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7663777.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="RD486_002053"
     CDS             24023..25777
                     /locus_tag="RD486_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663778.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKNQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
BASE COUNT         7850 a         5239 c         4516 g         8179 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat tgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa actgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaaaccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaa
//
LOCUS       DAPBBV010000040        25615 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.040, whole genome shotgun sequence.
ACCESSION   DAPBBV010000040 DAPBBV010000000
VERSION     DAPBBV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.040"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            391..1431
                     /locus_tag="RD486_002054"
     CDS             391..1431
                     /locus_tag="RD486_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDT7663779.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SSPSTITKDWLE"
     gene            2272..2604
                     /locus_tag="RD486_002055"
     CDS             2272..2604
                     /locus_tag="RD486_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDT7663780.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            3223..3564
                     /locus_tag="RD486_002056"
     CDS             3223..3564
                     /locus_tag="RD486_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HDT7663781.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     NEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            3583..3873
                     /locus_tag="RD486_002057"
     CDS             3583..3873
                     /locus_tag="RD486_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663782.1"
                     /translation="MKFFEVKSPYYYALIAAKNEEECAELYEQVVTDIENREEFIRCL
                     HELNRNEAIQEDAKKISEETLQPIGMEEATKDIFTIIDEQKSCVLSIDSTLV"
     gene            4065..4298
                     /locus_tag="RD486_002058"
     CDS             4065..4298
                     /locus_tag="RD486_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663783.1"
                     /translation="MARPVLDAMDMDTLTKGRYVQLLARGYSPKDVFKALSKGTDMEK
                     ERLRKEFDYWREHNGIKDLKPARPVIRRKKLKK"
     gene            4704..5375
                     /locus_tag="RD486_002059"
     CDS             4704..5375
                     /locus_tag="RD486_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDT7663784.1"
                     /translation="MKKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPID
                     QINEHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQAFAQIQIPALGLTLPIFK
                     GANQYTLSLGAATYFYEDAEMRKGNYVLAGHNMEIPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            5428..7407
                     /locus_tag="RD486_002060"
     CDS             5428..7407
                     /locus_tag="RD486_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7663785.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDVDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQAL
                     PREDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNNS
                     KGNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELT
                     KFGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVE
                     VPSEVVVGSDKEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVID
                     KTVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDT
                     AGQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASL
                     HGQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLK
                     VDSGLFGTGIKATPLESAEFAAKNAEGKYYGGLVDTDKNGVKEAVWVDDVANAAILKS
                     DKEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKAS
                     VPMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            7422..8174
                     /locus_tag="RD486_002061"
     CDS             7422..8174
                     /locus_tag="RD486_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7663786.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWTWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            8190..8951
                     /locus_tag="RD486_002062"
     CDS             8190..8951
                     /locus_tag="RD486_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663787.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLFSDQLKLVSNGKTKTIDQQT
                     GVFEFSIEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            8964..9224
                     /locus_tag="RD486_002063"
     CDS             8964..9224
                     /locus_tag="RD486_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663788.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            9221..11311
                     /locus_tag="RD486_002064"
     CDS             9221..11311
                     /locus_tag="RD486_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7663789.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKTTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            11338..11802
                     /locus_tag="RD486_002065"
     CDS             11338..11802
                     /locus_tag="RD486_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663790.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            11799..12041
                     /locus_tag="RD486_002066"
     CDS             11799..12041
                     /locus_tag="RD486_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HDT7663791.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            12059..12361
                     /locus_tag="RD486_002067"
     CDS             12059..12361
                     /locus_tag="RD486_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663792.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            12431..14494
                     /locus_tag="RD486_002068"
     CDS             12431..14494
                     /locus_tag="RD486_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663793.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHEGRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYSTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEKENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHEIAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIRERKEEFYQGLRTDKLKISKELNEQLNKLYQIT
                     SEALMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEE
                     AQEQARKEYEQQLEELLNRTNQATTESSMENSKESDPSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            14494..17103
                     /locus_tag="RD486_002069"
     CDS             14494..17103
                     /locus_tag="RD486_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDT7663794.1"
                     /translation="MRVRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAILMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGGFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPENDYRQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHQGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKRGETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     TNSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMH
                     DQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLHQNEEITEVIR
                     KRLLLEAEKAVKE"
     gene            17100..19496
                     /locus_tag="RD486_002070"
     CDS             17100..19496
                     /locus_tag="RD486_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663795.1"
                     /translation="MIIGGIFSGIANWWSGLFGDGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLETDPNKVESLPTDKRNALTAKNFKTANINSVII
                     PKEAAKMADEDKSGLSDIQKDRLRALQYRLELDDNGKEIPVEISDEGLAKYVYTSGYR
                     RYISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSNLNDIRKNGF
                     GNRKDVIPDNGEEQPDDKATIVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQY
                     RYKSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSMKIGLPKTQNLP
                     MKDSRLNQFKENDQSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNVSIQN
                     VVTREAAPEPIQKVHTGYKPANVAFTAPTKINVTRETKNRNNELKEQLLRDIKQDIKP
                     "
     gene            19548..19880
                     /locus_tag="RD486_002071"
     CDS             19548..19880
                     /locus_tag="RD486_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663796.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            19881..20474
                     /locus_tag="RD486_002072"
     CDS             19881..20474
                     /locus_tag="RD486_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663797.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLVTKE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVQTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            20637..22661
                     /locus_tag="RD486_002073"
     CDS             20637..22661
                     /locus_tag="RD486_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDT7663798.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASRLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            22661..23866
                     /locus_tag="RD486_002074"
     CDS             22661..23866
                     /locus_tag="RD486_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDT7663799.1"
                     /translation="MENQDESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNDNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPFLNSSKK"
     gene            23882..24526
                     /locus_tag="RD486_002075"
     CDS             23882..24526
                     /locus_tag="RD486_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663800.1"
                     /translation="MENKTLKIVLTAALSISLIGNIALFWQLKEEQATNTYKIEEVAK
                     NASEKLKKNFSEAQAKIDKLNQTINEKNQEIDQLKQQDGIKAKEEVTDAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAETS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            24537..25343
                     /locus_tag="RD486_002076"
     CDS             24537..25343
                     /locus_tag="RD486_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663801.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFTILGFLILASPIYTHKKVNI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQGLLKELANLDYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIVPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDDNYEQHAINYKVKGYKKEQKAAQKQIESLQATIDLNEELVNKLKDQLP
                     YQVADDQENTENKINDYQQEIETSKTQMKDQEEIIQKIQEKIDRMTKENI"
     gene            25366..25596
                     /locus_tag="RD486_002077"
     CDS             25366..25596
                     /locus_tag="RD486_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663802.1"
                     /translation="MKGANLVGKDIFAEQKVLIKAYLKVVKAKEICQEVNLSNTTISE
                     LKNGRKSLDTLKIRSFEALYLAAKKYFTAERK"
BASE COUNT         9448 a         3912 c         5197 g         7058 t
ORIGIN      
        1 gcctaaagcc ttgtcttata agaataatat aatatatact actgaaataa ggtagtatat
       61 attactagta gtggtagtat gttttatatg cataaggtag ttcttaattt attttttgtt
      121 ttgatactgg tagtacttaa ttatccttaa ttttaaaacc aaattttatt catacgttct
      181 tctggtagta tttaattata aataatattt atttaaagta gttcttaatg actttaaagg
      241 tagtacataa ttcattttat ttcttatttt aggtagtatt taattaaaaa acagttttaa
      301 tgcgtttgca ttttttattt atctttgcta ttttcgaaaa gagtaggtaa ttttacataa
      361 ataaaacaac gtgaaagtag aggatctaca atgactgatt ttaatttttt taaggcggat
      421 agagtttaca acgaattatt ttatcaattt ccaaaagtct ttattgtttc tgacgaatac
      481 aaaaaaatga aagattcaac taagattgcc tatatgcttt taaaagcaag attagagatc
      541 gcaatcagca aacggcaaat cgatgaagaa ggtaatgttt attttactta tacgacaaat
      601 gaactatgta gcgtattaaa ctgccaaaaa caaaaagcga tagcaatcaa aaaagagttg
      661 gaatcctttg gtttattatt acaaaagcag atgggattta acaaacagtt agggaaaaat
      721 aatcctaata gactatatct agcagaatta aaagtctcag aaaatgatat ctacttactc
      781 gaaaaatttg atagagagaa tagggaaaat gttgataaat cagagggtat gaaaatcata
      841 cccaccctcg acgaaaaatc agacgctgaa tcccttgggg ctcaagaggg tatgaaaatc
      901 ataccgtgcc aaaacgttga taaatcagag ggtatgaaaa tcataccaga acttaataat
      961 aatatattag acactaatag acacaatata gacactgaaa aagaccgcct acaagatcaa
     1021 ttgttgttag acaattttga gacaattatg acaaacgaca gcattgctac gtttgtccct
     1081 gaacgagtat taaatttgat aaaaacattt tcttcaagtt acagtgaagc tcaaaaaacc
     1141 gtccagacta ttcataatgc aaagaaaaaa gctgaaatag aaagtggtat ttcgatagtt
     1201 tttgaagaac tcgatagtta ttatgtcaat gcagaacaag aattatacac gacactgtta
     1261 aaagcctatc aaaaattaaa aaccgaaaaa gtcgaaaata tccagaacct gatttttgtc
     1321 tatgtaaaaa attggtttat cgaaaaacca atagctgcta aagtatcaag tgaaaaacgt
     1381 ttgaattctg aaagctcccc aagcactatt acgaaagact ggttagagtg aaactttact
     1441 gacaaagtga ttgttgcttc atggagtaac attaaagtta aaaatttttt attattctaa
     1501 ttatattacg aatattacaa aataatagct attttaatag aatttataag ttaaaatatt
     1561 atgataaaaa tcacaaacgt agccttttac gtcataagtg ttaaaagaaa taattaattt
     1621 caaatataaa aaagggaacg tatgtttgca tactcctttt ttttgagtta taataatacg
     1681 cgaagagaga taatttcatt atttaaacaa actaaaaatc ttgatattac ttcttttcag
     1741 gcaatacgaa tattattcgc ttacattttt ttgtataaat ttagttgttt taaatttaat
     1801 tgtctgctat gcctgtgatg aattgatttt cgttctgcac ttttggacga taaatttgga
     1861 caattgaaaa tacaaaaaaa aagaaaggcg gtatgaactc ggaaggctgg taaccttcgt
     1921 cagcgttcat acacggcatt aagatttggc ccttaatgcg ttaacctttc agtgttacgg
     1981 tattacccgc aatggattta gtataacaga tattcaaaag tgataccact ttttttggct
     2041 gtgttaaggt taaaaatacg tgatattacg atgaatctat gcctaagcat aatgttataa
     2101 aaatgtccgt gtggctcttt gccgtatgac gaacgctgaa attagaggga acgcatgttt
     2161 ggatgcgttc cctctttttt gtttgtcatg aacgaaaatc aattctctat ttttgaaaaa
     2221 taacaagaaa aacttgttaa aaatatttaa agaaattggg tggtttattt tatgtcatat
     2281 acaggaattt tgagtctcaa agatatttgt cactacggta aacggtgtac cgctacagag
     2341 aaaatcacga agaaactatc aactggccaa agtaaaaccg ttgtgcagtg taagaaatat
     2401 ataatccaga aagacaaagt ctcagaggaa atgatttatt acattgggaa acaaaagcaa
     2461 ataattttaa aagatcctat ccccttaaaa gagctatatc caacaatcaa acatgtttat
     2521 gaccaaaacg gtgtactgat tggtcgaaga aaaaatggag tcttgcgttg taccgcaaaa
     2581 gggatggggc gtttaatcag ctgaattgat cattctcata acttgtattt tatcgttttt
     2641 cgcttgcttg aaaatattgt cgagacttct aaaagaactt agaatcatta gaaaaataag
     2701 gagtagactt gatctatcaa caatttcctt cggggagtga cggggtagat ttttacgatt
     2761 ggtaacgtaa aaaattggtc aatcgagtaa atgcgcttgt ttggatagtg gtgaaatgaa
     2821 tttgtgtaaa taatatacac agagtaaaca agagggaatt tagaggttag acaagttaga
     2881 atagcgccta gattaatcat gagcagctac taagggatct aggctttgac gcaaactcat
     2941 ggaataagga gtaggtcttc tcgtaatggg gaggacgcac aagaaattgt gtcgtgtgct
     3001 gcagtacatg tagatacttg cgaggacgtt ggtcattggg tcaatcgagc atttaccgct
     3061 gtctactagg gtttctcgtt tcggacgcca taaacgagtc gatatttttt atgtattttt
     3121 aagtaaacga aaaacgataa aatatgaacg agtcctgaat aaagtgaaaa aattgatata
     3181 aaacatagag aaaatgaaat ttacgtaatg gaggaatgac aaatgaaaaa ttatgatccg
     3241 aatatacgat tgggcacaca tactattaag gtttctttcc aacgttggga ttacaaaggt
     3301 tttgtgacgt ttagaagagg cggaaattgt aaaggattag atgttttagc attaaacgag
     3361 gatgatttat acgatcaaac attgactgat aatccaattg gattcggctt gctacctgaa
     3421 gatgatgaag gtaatgaatg gtttaaaatg acgcttatga atgataatgg agacgaatta
     3481 tctgttgaag atacttggtc atatttgagt gattatattg tcagcgttga aatcattgaa
     3541 tttgtagcgg ataaagaaga ataaaaactg gaggaataaa ttatgaaatt tttcgaagta
     3601 aaatcaccat actattatgc gttaatcgca gcaaagaatg aagaagaatg tgcagaattg
     3661 tatgaacaag tagtaacaga tatcgaaaat cgtgaagaat ttattcgatg tttgcatgag
     3721 ttaaatcgaa atgaagcaat tcaagaggat gcgaaaaaaa ttagtgaaga aacgttacaa
     3781 ccaatcggta tggaggaagc tacaaaagac atttttacaa ttattgatga acaaaaatct
     3841 tgtgtattaa gcattgattc tacattggtt taatagatcc aagattctat aatttttttc
     3901 aaagtaaaaa gaaattaggt aatgattctc agaccaatta cttaggaaaa taaccataca
     3961 aattagattt tacagataaa ggattagaag gaatcacggc gattaataaa aaggtagtat
     4021 taccttaggc attgagtaag gaatttattt aggaggaaaa ttagatggcg cgaccagttt
     4081 tagatgcgat ggatatggat actttgacaa aaggaaggta tgtacagctg ttagctcgtg
     4141 gttattcacc taaagatgta ttcaaagccc tatctaaagg aacagatatg gaaaaagaaa
     4201 gattacgaaa agaattcgac tattggagag agcataacgg aataaaagat ttaaaaccag
     4261 cacgtccagt tattagacga aaaaaattga agaagtaaga ccaaagcgta tggcgtacat
     4321 aggctttttt attttgataa aaataatgaa aggaaggaaa actcatgaat tgtaaagaaa
     4381 tcgaaaatag aaaaaaagtg tcgaaagaaa tggaagaaaa gttactaaaa acaatgaaac
     4441 aaaaacaatg aaacaaaaac accttaaaag attatctgtc gcgcaatata tcaatgatat
     4501 gcagttaaca ggaaaagaga aagcttgttt gttaggttca atgaaaaact ttgaacagtt
     4561 gagacgaact tatgtgaaaa aaagttctaa ttgtcaacta ttgttagaag tctcatgaca
     4621 ttcattaata gaattcattt ttaaaacttt ttctatggaa atgagaaaaa gtttttttgt
     4681 tttgtctgaa aggaggcaga tggatgaaaa aatggttatt tggtttttta ggagtcgctt
     4741 taatcgtctt ttgcagtgtg tttggctatg ttagctacca aaaacatgaa ggagaggtgt
     4801 ttaagcaaaa tatagaaaaa aagatgccca tagatcaaat caatgaacat gcaaagagtt
     4861 ataaggagga tgcaacgaac gttaataatg atatgtcttt gggacaaatg ttgtccatac
     4921 aaaaagaagc aatcgaaatg ggcgtcaata aacaagcctt tgcacaaatt cagattcctg
     4981 cgcttggttt aacattgccg atttttaaag gtgcaaatca atacacattg agtcttggtg
     5041 cggctactta tttttatgag gatgccgaaa tgcgcaaagg aaactatgtt ctagcaggtc
     5101 ataacatgga aattccaggt gttttatttt ctgatattca aaagttgtca ctaggggagg
     5161 tgatggactt agttagtaac gatggcgtct atcgttacaa ggtaacgcgt aaatttatcg
     5221 tacctgagta ctttaaatta atcgatggcg ttcctgaaga gaactctttc ttgtctttac
     5281 caaagaaagg agagaaaccc ttattaacgt tgtttacttg tgtttatacg tcacaaggaa
     5341 aagaaagata cgtggtacag ggagagctac aataacaagg ttttaatcaa cgtgagtcgt
     5401 tgaaatatga aacgaggaga gtaaaaaatg gcaataaatc ggtatgtaaa aaaagctgga
     5461 atgcttgttg gaatgttagg aatcattgca ggctgctttc agggatatcg agcatatgca
     5521 gaagatgtca cgcaaaaaac gccaccagag aaggtcaata tcacggttca taaattaatg
     5581 tatgatcaag gaacgcaatt gaatgttgat gttgacggga tcaaaaacga tggttatacg
     5641 cacgatcaat atcctacggg tgtaacgaaa tacaacaagg cagattatgg tgatgttgag
     5701 tttacgttag gaaatattac ggatcaagca ttaccgaggg aagattctga tctaaccaac
     5761 gcgaaagtgg acgaaatcgt taaagatgta gaagacaagg gatctaacag tgagtacgtc
     5821 aagaatgcaa ccaacaaaat tacttcagct gtagatgaaa atggtgagat tacttttgct
     5881 gatcaaccag cctatgtcaa caattccaaa gggaatgtat atgtggttta tgaaagtaaa
     5941 tccgctgctg gattagtcac acaaaaagca aaaccaatgg ttgtgattgc gccaatgact
     6001 gataatacag gttcaggttt tttaaaagac attcacttat atcctaaaaa tattgtttct
     6061 aagttgagtt ttgaattaac gaaatttggt gacgatggca cagctcaaag caaacaaaca
     6121 cctttaaaag gggcaaaatt tgagttatac aagggcgaac ctggaaaagg aacaaaatta
     6181 ggagatcttg tatcggatga tcaaggaaag ctgactgcta ctgatttgac gttaggaaaa
     6241 tactattttg tggaagttcc ttcagaagtt gtagtgggat cagataaaga accaacagcc
     6301 gatcaatatt tattaggcgc agacgctcgc aacgatgcgc acaataaatt aacctttgaa
     6361 attacgaatg atggcgtgac aagtgactta aaagcttcat acgtaaacta taaagcacca
     6421 gtgatcgata aaacagtaac aaatggaaca ggacaagaac attctttcca aattggtgac
     6481 gcagtaaatt atcaaggaac gattcatatc ccaacagaca ttgcaggcgg agcagacggt
     6541 atcacagtaa acggagtgaa aagcgaaact tctccttaca gtgtatttaa atggggggat
     6601 acagcaggac aaggactttc ttatgtcgct gctaaagcaa atatcaaagt aacaaataaa
     6661 gatggatctg tggtattaaa agaaaataca gattataaaa tccaaaattc agaaaatggc
     6721 tttgtgatcg attttatcgt gaataatggc caagtaagtg atactgtagc aagtttacac
     6781 ggacaagatc ttcaaatgac ttataacatg tatgtaaatg acagcgcagc tgttgccaat
     6841 ccattaacaa atagcgtgga tttcgtttat aacaacaatc catttaatca ggaagaacac
     6901 cacgaaaaaa cgaaagctga cgttgtgact tatggtgcaa aattcttaaa agtcgatagc
     6961 ggactatttg gaacaggaat caaagcaaca ccgcttgaaa gcgcagaatt tgctgctaaa
     7021 aacgcagaag gaaaatatta tggtggatta gttgatacgg ataaaaacgg tgtcaaagaa
     7081 gcagtatggg tagacgatgt agcaaatgca gcgatcctaa aatcagataa agaaggtcac
     7141 tttgaaatca ctggtttaac tgaaggtgaa tattcactgg aagaaacaaa agcgcctgaa
     7201 aactatcaaa aattaacgaa agagatctct ttcaaagtag acaaagattc atacaaagaa
     7261 gaaaaccgaa ttacgatcaa aaacaatcaa aaagcttccg taccaatgac cggtagcaac
     7321 ggttttcaaa cgtatgtatt aatctcttgc ttgttgctag gagcaggggc actttctgca
     7381 gttgtttact ttaagaagaa agcctagaag gatcaaaacc aatgattatc aggaagccta
     7441 agaaaaagcg aatcatgggt aaatggatca ttgctttctg gttactttca gctgtaggtg
     7501 tcttactttt gatgcctgct gaagcgagcg tggcgaaata ccaacaaaat cagcagattg
     7561 ccgcaatcga tcgaacagga acggcagcag aaacggattc ttctttggat gttgctaaga
     7621 ttgagttagg cgatcctgtt ggtattctta caattccaag tatttcttta aaactaccaa
     7681 tttatgacgg aacgtccgac aaaattttag aaaatggtgt aggtattacg gaaggaactg
     7741 gtgatattac aggaggaaac ggtaaaaatc ctttaatcgc aggtcatagt ggactttata
     7801 aagataatct ttttgatgat ttaccttcag taaaaaaggg agaaaagttt tatatcaaag
     7861 ttgatggtga gcagcacgct tatcaaatcg atcggattga ggaagtgcaa aaagacgaac
     7921 tacaaagaaa ctttgtcact tacttagaac caaatcccaa tgaagatcga gtaacgctaa
     7981 tgacatgtac gcctaagggg atcaacacac accgttttct agtgtatggg aagcgagtaa
     8041 cctttacaaa atcagaatta aaagatgaag aaaataagaa acaaaaatta tcttggacat
     8101 ggcttttagg aagtactgtt tttctttcag tcatgatcat tggttcgcta tttgtttata
     8161 aaaagaaaaa ataaaggagg gtaaccaaca tgagaaatag aaaatggcta tttgtttgtg
     8221 cagccgctct tttttctttc actgcctaca cacagttgac gtttgcagac agacaagaaa
     8281 gcacggatag cacagaacaa acaatccaaa cgtcagatag cagcacgatt caaagcagcg
     8341 atgaaaccgt cgattcgtca acagttgatt cttcagaaga accgaaaatt gctgaagacg
     8401 atcaaatagt caaacagacc attcacgttc aaaaaattat ttcttccgaa caattagaca
     8461 accaggggca aaaacttgaa aaacaagaag gagtaaatgg cgcgaagttt tctgtttatg
     8521 atgtatcgga cattttacaa aagatggatg ttaaggatct cactactgac caaattgaat
     8581 cccaattaaa agatcgagtg aaaaaactat tcagtgatca attgaagcta gtttctaatg
     8641 gaaaaacaaa gacaattgat caacaaacag gtgtctttga attctcgata gaagtacagg
     8701 caaatcagaa acaagcttat tatattgtca atgaatcaag tcctgaaaac atttctaata
     8761 gcgaggatat tttgctatta acacctgttt ctgataaaaa cggtgaattc ttaaaggatg
     8821 tgtggatcta tcctaaatca gaagcttcgc aacctaaaga agaagtaaaa aaaatcgttt
     8881 ctactggcgt aaagaaaaac ttctttgaga attgttggga ttttgttact cacttgtttt
     8941 ctagagatta aggaagaaat aaaatgaaac tgatcaaatt attattattc aatttttctt
     9001 gtttaaccgc agtctttttg tactgcggtt tattattttc taaactatct attttgccaa
     9061 gctaccaact atacctaatg aggattttaa acataccagc tgcttccatg ccgctagata
     9121 ttatggaaaa gctcattagg aatccattat ttactacgat caatttgatc gttattgtcg
     9181 gaatttcact agtcatttat aaaaaagagg ggatgaaggg atgaatttta aacactcgtg
     9241 gacaagacgg ttaaaatatg tttttcccat aatgatgatg ttaggtacat tgtttgggtt
     9301 aaaaacagcc aatgtctttg ctgaaaaagt tattgtcgat ccgtcaaatc caatccagaa
     9361 cgtaaagaat aattttatta ttccaaaaga tgttcctaat gcaaaaacaa atattactgt
     9421 aaacggagcg tcaaaagttt acaaatatca tgttgatgcc aacaaaggtg gttttacaga
     9481 cgactacgta ggattagtgg agggaaacaa aaatatacgc tatccttctt tccaaaaaga
     9541 atacggtgaa acaaaccttg ttttagaagg cgtaacaacc aacaccaaag tcaatattga
     9601 ctatggaaaa atcggtacgt ataacgggaa aaaagtcaat atcaagctag ttctatctaa
     9661 tattcactta tactcggata cgttgccgtg gaatctacta gataacaact atacaaaaac
     9721 tcattttcga gacgatggct ataaaaatac gaatggtgca atgagtaaat ctaaaaaaag
     9781 aacagtactt tggatctcag acaatctttt ctcaggaatt gtttaccatt caacacaaat
     9841 gaatgtgcag ctagtagcca catatgagga cggtagcccc gttcaatttt caggagatac
     9901 atttatcagt tttaactctt tgaaccctgc aggaggaaaa accacggatc ttaaaggaga
     9961 atatgcccac tatgacaaaa tgaatacgac agattggtat gtcagaaaag atacggttct
    10021 ttcagaattt aaatctttct acaacaatct gaacgtggta ggtggccacc caggaggaag
    10081 ctctaagctg acacaagcgg ataatgattt caataatttg catgataaat taggagatcc
    10141 gaagtttggt caaggtactg tgtcctttaa aatatctgaa gcaaatccga cgtttgtgat
    10201 tggttcttct aatgttcaaa cctggtttac tttatcttct gcgacaatct ttagtgttgt
    10261 tcctgatcaa cctgaaaaaa caggggttga taaaaatgga aataacgtga acgataaaat
    10321 gttgcaagta ggagacacga ttcaatatcg aatcaaacag aaggtgaatc gattaggagt
    10381 ggatttacta gcggtttacg atcgatttga gttaatcgat aatttaccaa aagaagtaaa
    10441 ttacgtcgat gcacacgttg aaagtggtac aaataaaaaa ttcgatgtat ctggtgaagt
    10501 gacctatgac aaaacaaaac accaggtaaa atatgcagcg aaagctgata cattaaaaaa
    10561 tcgaatgaag tataacggcg aaacttacga attagtgatc aatgtaaaag tcaatgaatt
    10621 ggccaatcaa aatagtgtag ccaaaaatca gggaacgtcg atcattaata aagtagaaaa
    10681 ggatacaaat atcattaccg tttatttccc taaaattcca gtgaaagaag tacaacaaaa
    10741 tggaaaagat gtaaacggac gaaatgacgg taagaagggt acgccgacag ctcctttaaa
    10801 cgcaggatct gaagtacaat atctagtcac acaaaaatgg cacacaaaag gcgtagacgc
    10861 tgcgtcagat cactacaaac aatttagtat tcaagatcca attgaagctc gtttgacata
    10921 taaagaaggt tctgcgcaag taatagataa gagtaaagga aaagatatta cttctgaagg
    10981 cacactaacc tatgatagca attcaagaac gctgaagtgg gaagcttccg ctgacttctt
    11041 aagtaacaat cttttagatg gacgagaaat tcagctgata tttacagcta aaactccatt
    11101 acaatcagaa aaaaatattg ataaccaagc cgtagtagca gtagataatg tttctaataa
    11161 aacaaatgtt gtgacaattg gggttgatcc taacttgcca caggtcattg ttcctaaaac
    11221 aggttctaca catttagtaa cgatttcagc ggtcagctta ctattacttg tgttagcaac
    11281 ttttagttat gcggttctga gatacattta aaataaaaaa acgaaagaat gaataaaatg
    11341 aaaaagttaa taatagtagt tacttccttg attgccatga ttgttatttt agtcggatgt
    11401 agtaatgaaa aaaataaaca aactaatcaa gataatggcg tattgaaatc aggaactatg
    11461 tggaaagaag aagtaggtgg tcttgtttat aatttgaaaa ttatagacga gactacctgg
    11521 gaatactctg agagtgtatg gcatccagat cctgtacaaa taacagtcaa gaggcaaaaa
    11581 gactataaag gtttagaaag atacaaaata gtagattcag ctggtgttag ggaatttata
    11641 aacaaatctg attctttatt tattgttgtt ccctatgaga agaatggcgt aaaaaaaata
    11701 atttttcttg gatctagcaa ggatgaaaag cgaacgaaag agaaattgat tcacgatgga
    11761 tcacaatcca ataaatataa gttacaaaag actagcgagt gattgctagt ctttttattt
    11821 gtcctgaagg aggaatcaca gtggcaaaag ctaaaacgcc atttgaaaaa gccgcgtcta
    11881 aaatcttaga acgccgcggt gtatctgaaa cacagtggaa acaagaagtc cttgaaaaag
    11941 cacaatttga cctattacgg ggaaaagaca aggacttaga aggatatatc tatcaacgtg
    12001 aacgtgaaaa gcttgttttc gacgaaatta ttaaacacta aaaggagcga acaattttat
    12061 gtttgaatca attacaatga attttttaac acaaccgaaa gtagtagctg cggttgatat
    12121 ttttagagca ttacaaactg ccgcaactag tttaaaaaac aatctgatga tttttgctgc
    12181 tgctgcggcc gttgcttcca ttgttattgg gggtcttttc ttcctatttg gacgaagagg
    12241 agctgaaaat gggaagatgc acgtaggcta tgtattgatg ggggtaggag ttattttagc
    12301 agcagcttct attgtggttt cgttatttgg attgtttgga caaacacctc aaggattata
    12361 agaaagtaaa aaagtaggag taagaagtag tcgatacttt ttactccttt tttatgaaag
    12421 gagaatactc atgtacttta cgattgcagg caataccaaa acagataaag agttaataaa
    12481 aaaagcaacg aaggaagtag gaaagcgtac ttctttttta ccgaaaacaa ttaaatattc
    12541 tgtcattgaa acggaagaac agctacatgt gttagggaaa gtactggaac acgaaggtcg
    12601 atcttctgtt aagttgactc tcacgttaca tgacacagaa ggaaaaatag agaaagctgg
    12661 tacagaatac gtttttggcc cactggatta tcaaatttca gaaggtttct attctacatt
    12721 gatggattta atccgccttg atgtgtttaa agaaacggat gaaactatga gtgtggaaga
    12781 gtcttatcga aacgaaaaac ttttacaagt tttagaagaa gagttagaga gcgaccaaag
    12841 aaaagtgaat caagggagtg aagtcgaagt aaatgaagaa gtaccatggg aacgaccaat
    12901 atttccaaag aaggagtcaa aagaaaaaga gacagtctat gttgacgaac aagctgatat
    12961 tccgactcag aaatcgatat ttgagaaaga gaacgatgtg atgggtcagt tggaggtaga
    13021 tccctttgaa gaaacaatgg aggatgaaga gacggccgaa gtagaagttg atccagttga
    13081 agctaatgaa gagtcaacat ggactgaagg ggattctcag gaatatattg aaccacttat
    13141 cagtgaagaa gtagaaaaaa acgaaataga gatacaaaag gcaactgtat ttgattatat
    13201 tttggatcaa tatccgccag agcatgaatg gatgaaagaa aaaaacaaat tatttttaaa
    13261 tgagctttat tcgaaatatc aattacccca aacctatcaa gcatttttag agagtaaaga
    13321 agaattaatc tcacagggta aaggcacact tttagaacag ttagagtctg tccaatcaac
    13381 aaattggcat gagattgcac aagaagattt attagccacc tttgaagaac gtcaacaaga
    13441 aacagatcaa gaaattaatg agtatgcgac ggaacagtcg tctaattggg agaaagcaaa
    13501 agaggaacta aataaagaag aacagcgagt gattgaagaa gaagtacaaa aaattaaaga
    13561 gcgatacgaa aagaaacgcg acaatgcgta ttccttgtgt gtagaaaaga tcaataattt
    13621 tactcagacg aatcaagaag cgttatcgaa agaaaaagaa aacttgttaa aagaacgtat
    13681 aagagaacga aaagaagaat tttatcaagg tttgcgtaca gataagctaa agattagcaa
    13741 agaattaaat gagcaactga ataagctcta tcaaataaca agtgaagctc ttatggaaaa
    13801 acacgagcag atccagcaag aattacaagt acaaattcca aaatggaaaa aagagtatga
    13861 aattcaacaa caagaattga aagaacaaga agaaaaacaa cggcaaaaag aaaaagagcg
    13921 cgaacaatta gaactaaaaa aacgtgaaca ggatcttgcg gaacaacaaa tggcaataga
    13981 aaaacaacgg ttaaaccaag aaaaggaaaa agaagcagct gctcgtaagg aacgtcaaga
    14041 acaaatggat acattacgac aagctcagtt aaattatcta gcacaacctc aaccaacgcc
    14101 ttcagtagct gctgttcaaa ccccaatgaa caaccaaaca aatctaactc cttcaccaca
    14161 gcgttccttt aacggatgga tggtgggatg tattgcaagt ttaagcttgc ttctaggtgg
    14221 agggacagta tttgctttta atcatatcaa tcaatcttca caggctgatt ctgtagccac
    14281 aacggcgtca atcaaggaag aagcccaaga acaagcaaga aaagagtatg aacaacaatt
    14341 ggaagaatta ttgaatcgta ccaatcaggc aacaacagag tcaagtatgg aaaatagcaa
    14401 agagagtgat cctagtaagg ctaaagaagg atcaagcgat tcaactgtac aatcaaacac
    14461 ttccgaaagt tcagaatcaa atgaggtgaa ataatgcgtg ttagagaaac aacgagacga
    14521 aaagacaaac gattcaattt agaaaagaat aggtatcttt ctcatttcta tcgctatact
    14581 ccttcaggag aagagctacc agaaaaacat gacaaacgta tttctcaaaa gattttttat
    14641 agtggcttag cttatcttcc tttaaactat gttgttacaa gaataccaga agcatttcat
    14701 cgatttgaga ttattccagg aagtttacaa ggagtgaata tttttcagtt acaagaaatg
    14761 ccgcagttat tccattttga ttcaactggt ttttggaatc ctttgacccc aacaacaagt
    14821 ttaggcacac gtttagttgt ttctacgatt tgtgttgttc cagctatact tatgggattg
    14881 aaaatggaca tgtggtttcg tcctctagca gatgggcaaa aaggagataa ccgattaaaa
    14941 acgttaaagg aaatccaaca aatttatccg caaataccag aatcaaaggg aggttttcct
    15001 ggttatggcg gaataccaat tactcattat aaaaagtact ggtatattca gacggataca
    15061 gtaaatactt gtattgttgg tacttcccgt tcagggaaag gacagataga agttttagca
    15121 accattgaca atttgtctcg tgcagaaaga caaagttcaa tggttgttaa tgatccaaaa
    15181 acagaattat atgttgctag taaagatgaa ctagaagcta gagggtatga tgtgtatgca
    15241 tttaatatca ccgatccact gcaatcaatg agtgataatc cattggcact catcgtgaaa
    15301 tactggaagc gaggagacat agatactgca acgcagttaa ccaatacttt tacgaatacg
    15361 atttattatg atgccaatgc ttcagacaac aaatacttta acgaaaatgc gcagaaagct
    15421 gtaaatgcgc ttatttttgc gttgttagaa caagccgatc aaacagggga ttactccaaa
    15481 ttaacaccca ataatcttgt tgagcttctt tctgaaattg gcggttttaa ttatcaagat
    15541 cctgagaatg attacagaca actcaatgcc ttagatgaat tcatgaatca gttaccacct
    15601 ggaaacatag caaaaaaaca atatggggca acaaaaattg gttctgataa agcaaaaggg
    15661 aatattttat cgacggcaat cacaggattg aatccattta ccctaacgaa aattgcgaaa
    15721 atgacttctc aatcaaccat tgattataag tccattggtt ttccgaagta tttggatctc
    15781 aaactacacg agagtctgtt aaatcagcga attgttgtag agttttatca tcaagggaaa
    15841 aaatttcatg aggaacgtgt caaagtaggt tatagaggtt tttgtgaaat caactttgat
    15901 tgtcatttag agcagggaga tcatgtttgc ttaaaatacg atcatcaagg aaaagaatat
    15961 gttgcttggt atgagttttc tcaaagagta ttgaaagacg aagagggaaa tatcgtttat
    16021 cgaaaaaaac gaggagaaac ccatttacca gaattagaaa aagaagctgt tctaacatta
    16081 gatgaggata aaagtaactt attagtagag tctattcgga tgcactatac cgataaacca
    16141 atggctattt ttatgctcac acctgattat gatccatcta accatatcat tgttagtatt
    16201 tttcttagtc agttgtataa agaattatct acgcaatgtg ttaagactaa aggagataaa
    16261 tgtcaccgta ggattcattt tattttagat gaatttggga atatgccacc aatggataat
    16321 atggaaggaa tcatgacagt cacagctggt agaaacatgt tgtgggatct gtttattcaa
    16381 tcctatcagc aactttatgc gaagtatggg gaacaaaacg cagcgattat caaagaaaat
    16441 tgtcagacac atatttatat tatgtcgaca gacgataata ccatcgaaga attttccaaa
    16501 aaagtgggga ataagacggt tgaacaagag aacagtacca ccaattcatt aggtatgaat
    16561 actcatatca atcgcaatgt tgattcagat cgtatcttaa ctcctgaaag aatttctact
    16621 tttttagaag gtgaaacgat tgtactcgct cctttaaaac gacaagattt gaaaggtcat
    16681 aaaatacggc cgtatcctat ttttaatcat ggggaaacga atcttcctta tgcttatcaa
    16741 tatattgaag atttcaatcc atcgtgggat atcaatgata tagacataca ttgtacacat
    16801 gcggacttgg atcttaaggc tttacaaatt gattacgatt attttctacc tgatatctat
    16861 gcacgtcgac tttatcacaa tatgcacgat caaatagaag aggaagctaa agaaaacatt
    16921 tttattaaaa tcgttcaatc tttagacaac tcaacggcac aaaagttact tattcaattt
    16981 tatgaagaga agcaaataga tcgtttgcaa gaataccttg aaaaattgca tcaaaatgaa
    17041 gaaattacag aggttataag gaaacgactt ttgctagaag ctgaaaaggc ggtgaaagaa
    17101 tgatcattgg aggaatattt tccggcattg ccaactggtg gtcaggctta tttggggatg
    17161 gggatgcaga tcccaaaacc gtaacgaaag tcttacaaga ttatggtaat tatctgcagt
    17221 atcaagatgt attcagttgg atttgtaata cttttttatg gggtttgatt aaagggttat
    17281 ataatctcaa tactttacta gaaaaaacaa tttatcaaag ctttgattta aaagacttat
    17341 tgaacgctgc tggtgttaat gaactgtttc aaagtttgat tagtaaggta ttggctcttt
    17401 tttgtgtcgt cacattaatt tatttaggct taaaattttt tatgagtaaa catccaccaa
    17461 aaatcaaaaa tatcttggtt aatctattta tggccatgat tttgattttt ggtggtagtt
    17521 ctttaatcga tgaagggcta aatattagta aaaactttta cggagacgtg actgcagcaa
    17581 ataaagcaga taaaactgga tcacctgctt ttcaaattat tcaaaataat gtgatcgatg
    17641 tgagtacgct actagaaact gatccgaata aagtagaatc cctaccaaca gataaaagaa
    17701 atgctctcac ggcgaaaaac tttaagacag caaatattaa ttcagtgatt attcctaagg
    17761 aagccgctaa gatggcggat gaagataaga gcggtctatc agatatacaa aaggatcggc
    17821 taagagcgtt acaataccga ctggaactgg atgataatgg aaaagaaatc cctgtagaga
    17881 ttagtgatga ggggttagca aaatatgtgt atacttcagg ctatcgccga tacattagta
    17941 gtccagggat tattttagct ggtgaatctt ctttgtcggt tgcctattta tttatcttgt
    18001 ttacgattgt aacttgcatt attgagctgg tatttaaaaa attctattta gtaattgccg
    18061 cgtcaacgga ctttgagaca ggacaacgga tgaaaagtgc tatagaagat atttctcaat
    18121 ccttcttgtt attggcgttt acgattttag aattacgaat ctatacatta atgctgtcag
    18181 gtatcggtga tttgcacgca gcaggcaaga tcaacggatt tttgtatgtt gtcgctttaa
    18241 ttgtactaac cattgcgcta ttcaaaggct ctcaatctgt tacgaagatt ttcggtgttg
    18301 atacaagtct gaaaaacggc agcaattctc ttcttagcat gtttgcctta ggaaatattg
    18361 cgaaaaatgt gggtagtggg gctaaaaacc ttgcaagtgc tggtaagagt ggtttaagca
    18421 atttaaatga tattcgtaaa aatggatttg gcaatcgaaa agatgttatt cctgataacg
    18481 gggaagaaca accagacgat aaagctacaa ttgtacctaa tagtaagaaa acagtttccg
    18541 aaatgttcgg gaaagcgaaa aatggtgttt ctaaagccgc agaaggtctt ggttacgtca
    18601 atgaacgtgg gttaaaagga acagctgaag atcttacaga aaaagccaaa gacaccttag
    18661 aagagaaatt agacggcacg agagctaaag aattggctga agctgtgaag aatccatccg
    18721 aagcactaga aaaacaaaaa gaaaaagctt cagaagtcaa agaaggacta aaagatgcgt
    18781 atggtgaagg acaagtcaat gcagcagtga aggcaaatac aacaagtgaa aaagaaaatc
    18841 aagaaggtgc agcgattcct tcagccaaag atcaccaaga tgagttacat tctaacgaaa
    18901 attcgatcgg agaaaaagat tcagaagaag gacaacatgg acagttacca aaaaccgatc
    18961 cagaacaata tcgttataaa tctaacatta attctgaaaa tgaaaagcgc atttcagatt
    19021 taccaaaacg aaatcaagaa gtacaaacgg atgaggattc catcgatttg ccaaatgata
    19081 atggaatcga agttggaact gaaaaatcaa tgaaaattgg tttgcctaag acacaaaatt
    19141 taccaatgaa agatagtcgt ttgaatcaat tcaaggagaa tgatcaaagc tttgttcacc
    19201 aatcaactgc aggtactgtt caaatgaaac caagtcgttt gcctgaaaat ggaaatctga
    19261 caactgtttc ttacaattta tctgaaagtg gtgagacagg gaatgtgtcc attcaaaatg
    19321 ttgtgacaag agaagctgca ccagaaccta ttcaaaaagt tcacacaggt tacaaaccag
    19381 caaatgtggc atttactgca ccaacaaaaa taaatgtaac aagagaaact aaaaacagga
    19441 acaatgaatt gaaagaacaa ctattgaggg atatcaaaca ggatatcaaa ccataaaagg
    19501 cctacgagtt aggccttttt tctatgtatg aaaaggagaa atcatttatg gataaatata
    19561 ttaacatgaa aaatcctcca agatttagtg gggaatggaa gtttttcgcc tttttctttt
    19621 tagatctatt aacgcttggt ggttgctttt tttgggcgaa aatagtcaat aatcttgtcc
    19681 acttaccact cttttttgca ctcttgaatt atggcttatg gattgcgata gctctagtga
    19741 ttgtttggcg accttataat aacccaggtc aacgacaaat ttttgcgatt atcgaatcta
    19801 ttttctttgc ggataagaac cactatcatg cgttagatcc taaccgaaat tatcatggta
    19861 cgtataagga ggatgaataa atgcgagtca aaggacaaaa ttcagttgat aagaaatcca
    19921 ttttgcagtt tggaaaacca gaagaacgat ctatcttgga tttatttcct tataaatcct
    19981 gtacagaaga gggagtctta gttactaaag aagatcattt tcaacgttat tatcgtgtag
    20041 tttctacaga cgtggaagga ttaaacgaac aagagaaact agaacgaatg aatcagttga
    20101 ccaccgtcat gcgtacgtat gtgcaaacaa ttaagttagt tagtttgacc acagagacgg
    20161 atctaacgga acaaatcgta caaaagcggc aattattaga taagaatcgt atggaacaat
    20221 ccttaggaag aaatctacag cgattaagaa aatatgaaaa gaaattagta gaggaaatcc
    20281 aggaattgaa acgagcagaa caagaacgtc ctgacttaag cttctttttc gtcattgaag
    20341 gaaagacaat caaggattta caaaccagaa atcgtcagtt aatgcgatct agtggcattt
    20401 tagggttaaa accactctac aaaaaagaat tgatcaagat tctttatcga atgaacaata
    20461 tgaatgatga gtaggaatgg agaagagaga atgaaatatc cgttgatatg gttagaaaat
    20521 gatgttccga aggaagagat cactagaaaa ttttctcaca ctttaagcct gggtaagttg
    20581 ggaaaagggc aatcttttaa ccaagtaaag aatcaaacaa gaagaggtga ctgtacatgt
    20641 tagaagcgat taaaacagct ttttcaccac aaaatgatca aaaagtactt gatccattaa
    20701 agcaactagg aaatcgggaa atagaaattt taaaatccaa agggtatgat ttagattttt
    20761 taaaacaagt gatgccacaa ggtggattaa atttcgatga agagtatgtg acctatggaa
    20821 atggttattc acgatgtgtg acagtctatc actatacaaa aaatcctact cttttttggt
    20881 tggccaatct catgaacaat cctcatacag tggccacact agatgttagc acagatgaaa
    20941 agcaaaaagt gattgatcaa atcaaccgcg cattagatga attaaatgat cgatcagata
    21001 atgaacgaaa agcgactgac cgaaataaaa gtgcggaaga atacctggaa ctagcggaat
    21061 atgcccgaaa attgacttct aatggggaaa tttctaaaca agtcaaagtg agagtacatg
    21121 tttacggaaa tacgatacaa gaagtggatg aacgggcgca ggaactgatc gaaaatctaa
    21181 aagggatgga ttatcgtgcg gtgacttatc tgcataaaac caaacgagat tggcaatcga
    21241 tgtttaccat gttcgatgaa caagctgaat ggttcggaaa tatcaaaggg caatcactac
    21301 catcgttaaa cattggcgga ggtttcccgt tccaccacca aacgctaaaa gatccaggag
    21361 gtacacaata tggggaaacc atgacaggcg gcccatttgt ctggaatgcg acgtataaaa
    21421 atagtgtacg gttgtctact aataccttgc ttctaggaat gatgggagct ggtaaatcga
    21481 ccgttcttaa aatgatcgcg gaagcccatt tagctgcagg agactttatt tggggctttg
    21541 aaaagggaaa agactttatt cctttcttaa aggaatataa cggtattatg gtgcgtttag
    21601 acggatctga cgggatgatc aatcctttag agatatttgc cacacggacg tatgatgaag
    21661 catccaggtt atatgacgat ggatcagtca aagatttgaa gatcaatgaa gcagcgtcct
    21721 atcaaacgca cttagacaaa gtagtctatc aggtacagtt agtgagtcct cagctaaaag
    21781 gaacgatgaa agcagaattt aagacctact taaatcgttt ttatgaagag tatggaacag
    21841 taccacgtgg ctttacttcc tcaaattcgc gttcaaatac tgatacgcaa gtcacaggta
    21901 aagatccaga agcttatccg acgttcaaag aatttttaga ctttttagga caactggaat
    21961 taccaggtgc ttcccaagag aaaaagaatc gaaaagaaga aatggaatcc atcgtagaat
    22021 ccttatgtga gacgtatggc atgatttttg atggtcacag tacgattcga caccttgacc
    22081 aacaacagtt ggtctttttt gacattgact ctattacagg tttagatcga ggggtgcaac
    22141 aatgtcaaat gtacatggct atgacgttga tttggaatca ggcattgatc cagggaagaa
    22201 gacaacgacg tttaattaaa gaaaaacaaa tggaagaaca agacttcaaa cgcttcttgg
    22261 cgatgattga tgagtgccat aatgcgatta atccagattt tattgaaacg gtaaattatg
    22321 tcacaaactt tcaacgagaa atgcgtaaag tagaagcaat gactgtttta gctacacaat
    22381 ccccacaaga aatggtgcca gaaaatatgt cttctgataa cttctcgaaa ctgaagaaag
    22441 tctttgaatt ttcttctacg aagatcttta tgcgtatgga tgaatctatt ttacgtcata
    22501 tagaaggact agtgggtaaa tcaatgacga actcagaatt agaatccatt cctcaacaaa
    22561 atcaaggaga cgctgtgatc aactttggat caaaagaaac cattcgcgtt cattttagtc
    22621 cgaacaaacg tcaattaaaa ttgtttgatg gaggaaaata atggaaaatc aagatgaaag
    22681 tttaatcaag cagtatgtta agcgtcgcgc aaagcggcgc ttatttttgt ggttgtttgg
    22741 tacttctgca ggtttgatta ctattttgat cactgtgttt gttaccctat ttctaatact
    22801 tgcggcgggt tcgattgata attcggattc agattcaagc agtggtggcg aagcttttac
    22861 aggagaatat tcggaaggct taccgattta taaagaaatc aaaggaagag gccctttttc
    22921 tgatgagatt gcgcaatatg ccgtaggtgc agcagtgaaa tataaattat taccaagtgt
    22981 gattctttcg caatacggtt atgaatcagc gtttggtacg tcggcgtccg caagaaatga
    23041 tctcaactat tttgggatta cttggtttga tggttgtctg tttcctaaag gaactgcacg
    23101 aggaattggt ggcattgaag gtggctggta catgaagttt cccaactcaa aagctgcatt
    23161 ctcctattac ggctttatgg tagccacaca atcaaatttt aatgcatgtg taggaaataa
    23221 aagccctggc gcaagcttat tgatcttagg acgaggtggt tatgccgctg caggaattac
    23281 tgaagatagt ccgtattata caggttgtat gtcgattatt acctcaaata aattaacaga
    23341 atatgatgaa tttgcgatca aacattgggg agaaggcgga aatgacaacg gtacgattac
    23401 tggtgaatgg acgaatcctt tccctggcag cagtttagat aaaagttcct tcagcggtgg
    23461 tcaattattt ggaacgaatc caggcggtga attccgtccg aatggtttcc atgatggatt
    23521 agactttggt tcagttgatc atccaggaag tgagattcat gcggttcatg gaggaaaagt
    23581 cgtgtacgtt ggaaatcctg gtatttcagg tttgggcgcg tgtgtgatcg tgattaatta
    23641 cgacggcttg aatatggtat atcaagaatt tgcaaatagt acaggaaatt cccgtgtgaa
    23701 agtgggagat caagtgaaag ttggtcaagt aatcgggata cgagatacag cacacttgca
    23761 tttaggcttc actcgaatgg attggcgtca agcacaagga cacgcattca cagatgatgg
    23821 tacatggatc gatccattac catttttgaa tagcagcaaa aaatagatca ggagaaaaaa
    23881 tatggaaaat aaaacgttaa aaatcgtctt aacagctgca ctcagcatta gcttaattgg
    23941 caatatcgcg ctcttttggc agctgaaaga ggaacaagcg acaaatacct ataaaattga
    24001 agaagtggct aaaaacgcgt ctgagaagct caaaaaaaat ttctctgagg cacaggcgaa
    24061 gatcgacaag ttaaatcaaa ccatcaatga gaaaaaccaa gaaatcgatc agctgaagca
    24121 acaagacggt ataaaagcaa aagaagaagt cacagatgcc caaagaaaga cggcagaaga
    24181 gttcggtcaa ttggccattg ataaatcact aagcagaaat gaattaacgg aaaaactaaa
    24241 agatgtcgca acccaagaag tgatcgacaa attaagtcct gcagatgatg atcaccaaca
    24301 tgatgattat ggaagttact cctttacatt aggtgacgtg caaacttacg ctgaaacaag
    24361 cagtgtaaaa gaggaacaaa attttgtcgt atttgttgat tatacaatcg gcaatcctca
    24421 attcaaagat gtcaaaccgc aaaaaataaa aggtggatta actgtcactg aaaaacaagt
    24481 agatggtcaa tggaaagtca cagactttag ttatttcact cgttaggagg aagaaaatga
    24541 gtaagaaaaa aggagcaaga caacgtttta aaaaacggaa aagttatctt agatggctgg
    24601 gaatctttac gattctcggc tttttgattc ttgctagtcc gatttatacg cataagaagg
    24661 taaacatacc agatgaggta agcacgaacg cttttttaaa cacgaaagaa ctgacaatgg
    24721 tatcaaaaga aaaaggagcg aatcagcaat tagtttttga atttgcgatt gacgatgagg
    24781 atcaaggctt attaaaagaa ctggctaatc ttgattatcg cgtagaagta aagacagcta
    24841 aaggtgatta tcaagcaata aaagccaaag tgatcaaggt gtctgatgat tattttgtag
    24901 tgaaattagc acatgtacca gaagaatata tcgccatgcg tttaaccatt gttcctgaaa
    24961 aaattgatcc aaaagtggat atgcaagaac cacaagatct gatttattac gttcacgaag
    25021 ataaggttaa ggatcaagtg aaagatgata attatgaaca acatgcgatc aattacaaag
    25081 tgaaaggata caagaaagaa caaaaagcag cacaaaaaca gattgaatcc ttgcaagcaa
    25141 ccattgattt gaatgaagaa ttagtgaata aactaaaaga ccaattgcct tatcaagtcg
    25201 cagatgatca ggaaaatact gaaaataaga ttaatgatta ccagcaagaa attgaaacat
    25261 cgaaaacgca aatgaaagat caagaagaga tcattcaaaa aattcaagaa aaaattgatc
    25321 gtatgacaaa agaaaatatt tagtagaaca ggtggagtga aagaaatgaa gggagcgaac
    25381 ttggtcggca aagatatttt cgctgagcag aaagtattga ttaaagccta tctcaaagtt
    25441 gtaaaagcta aagaaatatg tcaagaagtg aatttatcta acacaacaat atctgagttg
    25501 aagaatggta gaaagagttt agatacctta aaaatcagat catttgaagc tttgtattta
    25561 gctgctaaaa aatattttac ggctgaaaga aaataaaaac aggaggattt tatgt
//
LOCUS       DAPBBV010000041        25502 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.041, whole genome shotgun sequence.
ACCESSION   DAPBBV010000041 DAPBBV010000000
VERSION     DAPBBV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.041"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            133..3660
                     /locus_tag="RD486_002078"
     CDS             133..3660
                     /locus_tag="RD486_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDT7663803.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="RD486_002079"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="RD486_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDT7663804.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="RD486_002080"
     CDS             7448..7789
                     /locus_tag="RD486_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7663805.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="RD486_002081"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="RD486_002081"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDT7663806.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="RD486_002082"
     CDS             9146..11566
                     /locus_tag="RD486_002082"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDT7663807.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="RD486_002083"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="RD486_002083"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDT7663808.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="RD486_002084"
     CDS             13000..13737
                     /locus_tag="RD486_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7663809.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="RD486_002085"
     CDS             13751..14566
                     /locus_tag="RD486_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDT7663810.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="RD486_002086"
     CDS             14579..15226
                     /locus_tag="RD486_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7663811.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="RD486_002087"
     CDS             15242..15898
                     /locus_tag="RD486_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7663812.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="RD486_002088"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="RD486_002088"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDT7663813.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="RD486_002089"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="RD486_002089"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDT7663814.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="RD486_002090"
     CDS             18240..18758
                     /locus_tag="RD486_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7663815.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="RD486_002091"
     CDS             18865..19365
                     /locus_tag="RD486_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7663816.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="RD486_002092"
     CDS             complement(19645..20565)
                     /locus_tag="RD486_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HDT7663817.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="RD486_002093"
     CDS             20730..21743
                     /locus_tag="RD486_002093"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HDT7663818.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="RD486_002094"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="RD486_002094"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDT7663819.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="RD486_002095"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="RD486_002095"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDT7663820.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="RD486_002096"
     CDS             complement(23383..24144)
                     /locus_tag="RD486_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7663821.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="RD486_002097"
     CDS             24333..25427
                     /locus_tag="RD486_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7663822.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4424 c         5384 g         7247 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg tgcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 gg
//
LOCUS       DAPBBV010000042        24896 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.042, whole genome shotgun sequence.
ACCESSION   DAPBBV010000042 DAPBBV010000000
VERSION     DAPBBV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.042"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            7..165
                     /locus_tag="RD486_002098"
     CDS             7..165
                     /locus_tag="RD486_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HDT7663823.1"
                     /translation="MSNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDEL
                     IPLENELR"
     gene            complement(914..1527)
                     /locus_tag="RD486_002099"
                     /pseudo
     CDS             complement(914..1527)
                     /locus_tag="RD486_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406632.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(2748..3452)
                     /locus_tag="RD486_002100"
     CDS             complement(2748..3452)
                     /locus_tag="RD486_002100"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012610.1,HMM:NF019322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7663824.1"
                     /translation="MIFDKVKEQIRKVYITTDRKSELLPSERDLAQEFSVSRPTIRKA
                     LASLEDEGIISKNEGRGYLVKPASEKYVDHELDSFIGFFQDAVQQGKKISSKIIQQTI
                     IPADSTISECLEIEQNTLVLVLERIRYIDDYPTCIAKSCIPLSVLPEIVEHDFAKESL
                     FSVLESRGIRLAYAKRSIEVTPPTDLENLYLDLEKNEPVFVFTSIGFAKNQKPFEYEI
                     SKYPAYKTKFESTVSK"
     gene            complement(3467..4336)
                     /locus_tag="RD486_002101"
     CDS             complement(3467..4336)
                     /locus_tag="RD486_002101"
                     /inference="COORDINATES: protein motif:HMM:NF012585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDT7663825.1"
                     /translation="MKIAVICSGGDSPGMNSALLAIKKTIDSEPDSEVVFFKNGYAGI
                     FKECIASVSLKEVEVFKAGTLIGTARFEKMRDLESRKIIIENLNKMEIDNLIVIGGNG
                     SLKGAELLKNESELQVSVIPGTIDNDFPNTDYTLGFDSALNTIIRSIDDLTSTANAHD
                     RIIIMEVMGRGCFALPEYASIANNTYWVERDDKEYLHLICKKFESEFYSPILLLPEGI
                     SNKQKIIEFITKNLPKETKYLNLAYLQRGSSPTFYDRYIGYLWGQLAAKELIEGKSGI
                     LSQKNGNIMLIPW"
     gene            complement(4444..5460)
                     /locus_tag="RD486_002102"
     CDS             complement(4444..5460)
                     /locus_tag="RD486_002102"
                     /inference="COORDINATES: protein motif:HMM:NF013539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7663826.1"
                     /translation="MFNFDQERFLKTQAGAVATNEQISNILESIASDLEEIYFIGSGG
                     VGILFDSTIEFARTRSTFPFHRVIAAEFMIHPNKTFSNKSLVVIPSLSGTTKETLELV
                     EYCNEMNVKTLALVGSPKTPLEKAATYSIYNDVLDDTSSENYYLQGLLIALFLMKQRN
                     EIDINQYNTYIEDLKKIPEALVHAKEQAEPMAKSFAKKHKDTSYHILTGAGDSFAEAY
                     YYGMCILEEMQWIKTRPVHAADFFHGTLELIEAGVSVIITEGEDDSRPLTERVKNFVP
                     KFTDVHVTVDTKDYDLPGISEDTRKIISPVVLATVFERISAFLEEERNHPLTTRRYYK
                     QMEY"
     gene            5650..8373
                     /locus_tag="RD486_002103"
     CDS             5650..8373
                     /locus_tag="RD486_002103"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012385.1,HMM:NF013070.1,HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7663827.1"
                     /translation="MKTKILKELNDLLNSYDFPQYFPEECNAQYIAQKFQIKRNTASK
                     HLNELMEQKKVVKINGRPVLFFPVHTIERYISHSLDSFEFSSIDSFREKISKKKADHF
                     FDDLIGAKQSLKEAVQQGISAMKYPGGLPIMYFGSSGVGKSYLVEKLAEYCRQTGIIH
                     ENAPFIELNCAQYFNNPELLTSQLFGHMKGSFTGADSDHIGIIEAADGGIVFLDEIHR
                     LPPEGQEKLFIHMDKGVFRRVGDSGPWRLSHVRYIFATTEQEENFFLETFRRRIPIVC
                     TLPNYQDREISERKEIVFHLLEKESTLINKEILVSEAALSFLIRLDLYGNIGELDGLI
                     KQTIANKLFSGSNKKYIEIHISDLPSRYLLTENIELKNQIASQRFYIFSNGNYVHDCD
                     ETSTVTTNLRGLIHRVSKYYSECHDVNRNSEEFRRFVKDQMAEFNDRFIYQKNSEVLV
                     KYYLPEIQNIVQKISPSLFVHLSGNTVQAIATYLAIRDQWGYGKENASANEIEKLYEN
                     LKCNYLTDLNVFLLIFENALDTTLTIWDKLYISLCVISETGNEAKDINAIILAHGYAT
                     ASSIANVANRLVNQFVIDSIDMPLDISFSEVIDRLLHYIEYRKPKDGLVIFVDMGSLA
                     QIKTEIEQVIEVPTMIINNVTTEMAIETAQLIQSTSDIQKVVKKLPYSQFEKQVLYPI
                     KIRKRTIVVSCNTGLGTSIKIKEMMENNLSKDLGIEFLPYENETLRDTQQLEFLIKTK
                     DIIAIIGTDDPRVSNIPYISLEELFDGEIGKLYKVLLRVYGKEIAEAINQNIVKNSSL
                     NRLIDSLTILDAEKVVNQIEESLKDYQMRVGKTLSSLSKINLYVHISCMIERLIRNQG
                     VSSYPAIDQFLKRYETEVASIQKALSKIEKLYNIKIPMEEIAYVCNIIVSY"
     gene            8501..8923
                     /locus_tag="RD486_002104"
     CDS             8501..8923
                     /locus_tag="RD486_002104"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose IIA subunit"
                     /protein_id="HDT7663828.1"
                     /translation="MRQILCMSHGPLAKGMIETLSIIVGDLDNIDFRCAYVDGNNDVE
                     MIIDDYLKESMGNETIVVTDIFGGSINNEWLRRLPDLSKVYLISGMNLSLLVDLYLKF
                     QLVSSDQIEEIIDHAIQASSGSIKFCNQLDYEQTVDDF"
     gene            8941..9411
                     /locus_tag="RD486_002105"
     CDS             8941..9411
                     /locus_tag="RD486_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7663829.1"
                     /translation="MIKLVRIDHRLIHGQVALTWTNAISADCILVANDEILNDPIQKT
                     TLKLAAPHNVKVVIKSIQDSIDAINSGKTDKYKLFVVTKTISDAKRLANGVEQIKSVN
                     IGSVKETSGSSALTHTIFVTEEERAELKGMVSEGIEVFAQQVPTDKAIDLKKSL"
     gene            9435..10217
                     /locus_tag="RD486_002106"
     CDS             9435..10217
                     /locus_tag="RD486_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7663830.1"
                     /translation="MDSLLVQAILLGLLTAFIVIDWMTGTNNLSRPIVSSVFVGLIMG
                     DLKMGIMMGATLELAFIGAITIGAARPPDTVSGGILGTAFAIATGKGAEFALTLAFPI
                     AALFLLVDNLLTLLVLPMIARKADRYAEKGELKNVSKMHVLGFILVKSLPRALFVGFS
                     FYLGSPVMERILNAIPTFVQDGINIAAGIMPALGFAILLQMLLKKDVFVYFVIGFALF
                     SYLHVPILGIAIFGACLAYIIVNMETKAAMGSRGEEMVEDDF"
     gene            10201..11031
                     /locus_tag="RD486_002107"
     CDS             10201..11031
                     /locus_tag="RD486_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014093338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7663831.1"
                     /translation="MKMTSSGKALTKDDLTKICIRSCALEASWNFERQQHMGFAFAMM
                     PALEKIYSGNEEEKQKAAQRHLEFFNTAPPLSTFIMGIVASMEEENAKNPDDFDTSTI
                     TSIKTALMGPLAGIGDSMFWGTLLVIGIGVGASLAKEGNILGPFLFLLIFNVPNFLLR
                     YFGVMQGYNFGTKLLENIESSGVMKTLTHAASILGLMVIGGMSGSMVSIKVAGSIGQG
                     DEATKIQSIIDGILPNLLSVLCVFLIYWMLKKGFKTTYVLFGIFIFGIIAAFFGFLTT
                     "
     gene            11066..12064
                     /locus_tag="RD486_002108"
     CDS             11066..12064
                     /locus_tag="RD486_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7663832.1"
                     /translation="MLNYNAKEMKKKGKRIYGIREDVEKIAKQAYDSGISNIFFTASG
                     GSVAVMQPFEYVLMTESSIPVYSMTAAELVLMGHKQLNEKSLVILYSKSGDTKETIKA
                     AEYLKERNVPTVGIVSKEDTPLEALSTYAINYLDGRPQEMPLYFLIMSIMNLNGEFPE
                     YTRFADELKNLPTALNSVREQADEKGKKYAEEFKEDPYQIWIGSGNLWGITYSYSMCV
                     LEESQWLRTKSVSSPEFFHGTLELVEKGVCVTLLKTEGETRLLDARVEKFAVQYTDKF
                     NVFDTKDYELPGISDEFRKYFCAPVMWAALGRVSVHLEDIRNHSLDKRRYYRVVEY"
     gene            12081..12935
                     /locus_tag="RD486_002109"
     CDS             12081..12935
                     /locus_tag="RD486_002109"
                     /inference="COORDINATES: protein motif:HMM:NF012515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663833.1"
                     /translation="MTAYVIGFGDNVVDYYENLNQKFPGGNAVNFAVNAKKSGVKAYY
                     VGSLSSDPDGVLLQHAISSEGVDISFSEVIDEPTEQAHVTIKDGDREFIGGVRGSRLT
                     PALSAELIDLMKNSSLVHTSCHSRTETKIKELKKYDVKVSFDFSDLDKYRTHEYLSDV
                     CPSIYIAQFSVATDDQEEINRLISECKDFEVPYLLFTRGSKSPVFVDTRENKTYEGFI
                     RKVESPHDTMGAGDAYFAAFASNFVLSKREKSMIEHVIDCFHKGANLAYETLMIDGSF
                     GHATPINP"
     gene            complement(13509..14759)
                     /locus_tag="RD486_002110"
                     /pseudo
     CDS             complement(13509..14759)
                     /locus_tag="RD486_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            15276..15467
                     /locus_tag="RD486_002111"
     CDS             15276..15467
                     /locus_tag="RD486_002111"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663834.1"
                     /translation="MGKYSFEFKSTIVQEYLEGEGGLGYLAKIQGVRSKKGTRMDQSK
                     VRPKNLTFGGRYLYGKISF"
     gene            15448..16859
                     /locus_tag="RD486_002112"
     CDS             join(15448..16003,16003..16859)
                     /locus_tag="RD486_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7663835.1"
                     /translation="MAKYPFELKLKIVKEYLSGVGEYRHLANKYGISSKSQVSDWVNA
                     YREYGEEGLLKKHQNQKYSVQFKLNALELYQTSEMSYREVASTLEMNNPALIANWMRN
                     FREAGIEGLSKEKGRPLTLTRKKENKKENTTTEERERIKALEKQVRSLQIENAFLKEL
                     RKLRKQEAQQRRKNQSHESSPASEDPFKLVELLETLKFPKATYMYWQKRFDRPNPDQE
                     IEEKMLEIRKEHKDYGCLRLKKELENQGIHVNKKKIQRLIKKLGIEVKSYTRKSRRYN
                     SYHGKVGTVAKNRIHRRFYTNICHQKITTDTTEFKYYEVDTTGVVRQKKLYLDPFMDF
                     YNSEILSYRISEKPNALAIMEGLEEAIQMTNDCPFRRTFHSDQGWAYQMNAYKNKLKQ
                     HKIFQSMSRKGNCLDNSPMENFFGLLKQEIFHGEVYRSLDELKTKIDQYIYYYNHKRI
                     KKKLNWRSPVQFREAVKTAV"
     gene            16934..18217
                     /locus_tag="RD486_002113"
                     /pseudo
     CDS             16934..18217
                     /locus_tag="RD486_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(18433..19245)
                     /locus_tag="RD486_002114"
     CDS             complement(18433..19245)
                     /locus_tag="RD486_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017867010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7663836.1"
                     /translation="MGDSKLTKKEINKVFWRSFALQGSESYTDMQGMGYSFSILPALN
                     KIYQGNDEKYYEAVYRNTEFFNTTPHISTFIMGMSLALEEENAKTDQFETETISSIKA
                     ALMGPVAGIGDSFYWGTFRVIAAGIGLSLAAQGNILGPILYFSIYTLLHFLGRYGCLR
                     IGYRMGANAIEKAFENNYLESFSLAASIVGLMSIGAMTSSLVRFTIPAVFKSKGGEIN
                     VQQMLDDIFPGILSLGLTFFVYFLLKKKVKVLWIILAIFVFSIVGVYIGLLG"
     gene            complement(19262..19993)
                     /locus_tag="RD486_002115"
     CDS             complement(19262..19993)
                     /locus_tag="RD486_002115"
                     /inference="COORDINATES: protein motif:HMM:NF015566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7663837.1"
                     /translation="MIECILIGIVGYLTTIDERYFGASMMNRPIIVGPVVGLILGDLH
                     QGILIGAALEAMFIGIVTIGAALPPDVGVAGTIATALAIKSGAGADVAVTLAMPFAVL
                     AQGLNMLAFTINSFTVSQGRKAIENRKLSSFQKWHFFPLIVRLPSAVLTFLVVYFGAN
                     ATESFVNIMPEKLMTGFTVASGLLPAVGFAMLIQGMIDKKSVPYFFIGYLLAAYLGVP
                     VVGVAVAAIMVALLVIQTKRNPVNI"
     gene            complement(20010..20465)
                     /locus_tag="RD486_002116"
     CDS             complement(20010..20465)
                     /locus_tag="RD486_002116"
                     /inference="COORDINATES: protein motif:HMM:NF015769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7663838.1"
                     /translation="MIKLLRIDDRLIHGQVAMAWTKSVSADYIIVVDDASANDKMKQM
                     ILSLAKPVSTGLDIITSADFLSTFEKRKNQNLMIVTSSPKSAFEIVNAIPGEVDSINI
                     GGLRYAEGKEKVNEYVAITSEDKNYLAKLKESGFKLIMQATPTGKAKIY"
     gene            complement(20458..20868)
                     /locus_tag="RD486_002117"
     CDS             complement(20458..20868)
                     /locus_tag="RD486_002117"
                     /inference="COORDINATES: protein motif:HMM:NF015567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7663839.1"
                     /translation="MYTIILASHKNLAKGMKETVEYILGPAPFIKVMTAYTDDNYDIE
                     KDTNILLDGTDKVLVITDLLGGSVNNHWMNYVYEKKLTKKITVIAGMTLSLIMELSMN
                     IEDYKLREKISMIIAESQKSIINCSELMEVEDND"
     gene            complement(21399..22358)
                     /locus_tag="RD486_002118"
                     /pseudo
     CDS             complement(21399..22358)
                     /locus_tag="RD486_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23219..23434)
                     /locus_tag="RD486_002119"
     CDS             complement(23219..23434)
                     /locus_tag="RD486_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HDT7663840.1"
                     /translation="MKKFIIPCIFLFLSILLFSTSILVGSYLDSSGMLIEPAFFCVPL
                     GYLTLGLAFFTALYSFVKQRLLKKYSA"
     gene            23917..>24896
                     /locus_tag="RD486_002120"
     CDS             23917..>24896
                     /locus_tag="RD486_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7663841.1"
                     /translation="MKKSAKDRVFDELIRLTGNMSSVTAEKISKNLGISRQNASHYLT
                     RLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQINEAFHSVVGHDGSLREVIQKCIAAV
                     KYPPNGLSVLINGATGVGKSFLATKIFEYAIHEQIIEEDAPFAILNCADYADNPELLS
                     ATLFGYKKGAFTGAEKDTEGLLATANNGYLFLDEVHRLSKENQEKLFVFIDTGNYRPV
                     GENVNWHSAKVRFIFATTEKSEDYLLDTFDRRIQISVMLPTFEDRPIRERLELIQLFF
                     QNEADILQKDIIVSKEALSLMLSHPFSGNIGKLKNIIKISCADVYSRTRE"
BASE COUNT         8157 a         4039 c         4747 g         7953 t
ORIGIN      
        1 agaaccattt ctaatatgaa agcaattatc aacagtaagg attacgaagg atataaagcc
       61 aaacatccag aagcgaaacc atttaaatac ccacaagaaa tgaagcgagc atggcgtaaa
      121 atgttagatg atgagttgat tccacttgaa aatgaattga ggtaaatgag aagagttaag
      181 aaaattgtac gattcaaaga tagtagtaaa gtggaagtgt agaaaatagg gatagatgtc
      241 ttttatttgt tcacatttta taacgaagta tttaagacag ctattgaata atgtttcctc
      301 cacctttttc attcatttac cccaccccgt tgttatatga ccgtgtttcg agagaaacca
      361 ataaaaagca taggctaact aggggttcct ttttcttttg attttttgga atccgcttaa
      421 gtgaaatgta tctgaaatga aacagagata aagtgatttt ttgctgtaat gacaaggttt
      481 tagctgtttc agataccatg taacccaaaa tagtttattg agaaaatagg agagtatttg
      541 atactaacta gtaggaaaaa atgagataaa aagtaaatgg aatcatttca ggtaatctca
      601 aataaaaaat atacaggcct gtggcacttt acctacggga ctgtatattt tttactctca
      661 gcgggcttgt tttgactccg tgtttgactc cgtcgtattg attttaaatg atattcgatg
      721 accaattaat aggtcgtttt tgaaattttt gtctctatat gactcagttt gataattatt
      781 gatagatcga tttgggtcta tatcgaacaa gggaagattg caaaagtcga agcttaaagg
      841 attgatatta aaggattaag aggtaaaaag gtatccccat aatatcctct gactccgttt
      901 ttgacctcgc ttatcatccg ttcatgtaag aatcaaataa ttcgactgtt tcattttgcc
      961 gattttttga tactttaata taaatgtcca tgattgtttt agaagaagaa tgtcctagcc
     1021 tatcttgtac atcttttact tgagcacctg cttcaaagag aagggtagca tgagtctttc
     1081 tgaagccatg gactttgatt atcttcatat ctgggaactt ccgtgctact ttatccatga
     1141 catggttagg gtagcctttg taaaggaagt cccttttttt attccctttg atagtgctga
     1201 ttacaggtat atcatctata ttatctatcc gaatccctct agaaaggttc ttttatgtta
     1261 cagaacgttt ccatttttta gaatacgtaa ggttccatta tcaattgaaa ttactccctt
     1321 tgatttgtct gtttttgtag gattaataca tagagagccc tcggatagtt ctactaacgt
     1381 tttgttgaag cagatagttt gattatcgaa atctatgtct ctacatgtca gtccgagtat
     1441 ttctcctttt cgttcccctg tataagaagc tattctaaag aatactaaag cacgctcatc
     1501 ttttaactta tgcaaacatt caaaaaacag atatttcaca tatatctaaa attcggagat
     1561 tgaaagaatg aatttatcta agaattttca ctaatgttgc gaatataata tcagaaaatt
     1621 tcgaaataaa ttttgttaaa aattagaaaa atccgaatac ttagtagtgg ataaattttt
     1681 ttcaggaata gtacgtttta ttaaaatgaa aactaatccg acatcaactt ttttatcgaa
     1741 gcaaacatca agcggtaaaa agacctcttt agtttgaaaa gtgttgcttt catattgatt
     1801 taaattttgg ttaagtaggt aaattaagaa atgatcagtg taagtatttc ctgatttagc
     1861 gcaccttgtt cactttgaaa atacaggttt ttgatggaca gattttgctt caaatgttta
     1921 aagaacatgc cactgtactt ggtacaggtc ggcgccccca tttggagttg cgtcagatcg
     1981 agtcgtgacg attcattttg tacaaattag aatttaaaat tgaatacatg acgcgcacat
     2041 tttcccagag agccatattc tgtaattaat cacagcaatt agtgattatg cacaatctaa
     2101 aaaactgatt tataataaaa atattattca aataaataat aataactgcc cgcatgatgt
     2161 tgacagttac aatagcacat agatagactg gcaaagatgg ttcttaatct ttcactttgg
     2221 tcagaattct tgggttatcc ttccagtgaa agtcagcaga aaatccttaa tgcttacaaa
     2281 taatttttgc gaaataggtt ttattggtaa aggactcaat catgaatatg aattactttt
     2341 atctggtaaa tttggaaaaa ttttgcaaag aaataaaaat tagacaaatt tgctacacat
     2401 aatcaaagat taaaaaagtt tttaaaatat agttgtttga atggggatat gaattagaga
     2461 aaattggttg attcaacggg tgctatcatt tttgatagcg tcatatgtga agtaagcaca
     2521 cctaatgaaa aaggttcagg cttgctttga agacttatta acaactatgt cgactatcct
     2581 tgacttaggg tagaggagta cctccacaca ccttaattag atgataatgt ttggactgta
     2641 ggctacttag cggattaaga taaagaggaa gtagaaaaag agccttgcgg aaagacactt
     2701 tatctgttat ccgcgaggct ctttatacat ttaagcatat ttaaaaatta tttggaaaca
     2761 gtactttcaa actttgtctt ataagcaggg tacttagata tttcatattc aaacggtttc
     2821 tgatttttag caaatccaat acttgtaaag acaaagactg gctcattttt ttctaaatca
     2881 agataaaggt tttctaaatc tgttggcggt gtaacttcaa ttgagcgttt ggcataagct
     2941 aatctaattc ccctactttc taatactgag aacagggatt ctttggcaaa atcatgttca
     3001 acaatttcag gtaaaacaga taggggaatg caactttttg caatacaagt tggatagtca
     3061 tcgatgtatc gaattctttc caagacaagc actaaagtat tctgctcaat ctccaaacat
     3121 tcactaattg ttgaatcagc aggtatgatg gtttgttgga taatcttaga actgattttc
     3181 tttccttgct gaaccgcatc ttggaagaat ccgataaaag agtcgagttc gtggtcaaca
     3241 tatttttctg aagctggttt cactagatac ccgcgacctt catttttaga aataattcct
     3301 tcgtcttcta aagaagctaa agctttccga attgttggac gactcaccga aaattcctgg
     3361 gccaaatctc tttccgaagg caataattca gatttccgat cagtggtgat atacactttt
     3421 cgaatttgtt cttttacttt gtcaaaaatc atagtaatcc atccttttac caaggtatta
     3481 acattatatt accatttttt tgacttaata tcccagattt tccttcaatt aattccttcg
     3541 ccgctaattg accccacaaa tagccaatat atcggtcata aaaagttgga gatgatccac
     3601 gctgaagata cgcaagattt aagtatttgg tttcttttgg taaatttttg gtaataaatt
     3661 caatgatttt ttgtttgtta gatatacctt ctggtaaaag caatataggc gagtagaact
     3721 ccgactcaaa ttttttacat attaagtgta agtattcctt gtcgtctctc tcaacccaat
     3781 aagtattatt tgcaatggaa gcgtactctg gaagagcaaa gcagcctcgg cccatgactt
     3841 ccattataat aatacgatca tgagcattag cagtagaagt taaatcatcg attgatcgga
     3901 ttatagtgtt taaggcgcta tcgaagccaa gtgtataatc ggtattgggg aaatcgttat
     3961 caatagtccc tgggatgaca gatacttgta attctgattc atttttcaat agttcagctc
     4021 ctttcaagga accgttacct ccaataacaa ttaagttgtc gatctccatc ttatttaggt
     4081 tttcaataat aattttccga ctttcgagat ctctcatttt ctcaaatctg gctgttccaa
     4141 taagtgttcc agctttgaat acctcaactt cttttagaga aactgaggca atacattcct
     4201 taaatattcc ggcataacca ttcttaaaaa agactacttc cgaatctggt tcgctatcaa
     4261 ttgttttttt tattgctaat aaagctgaat tcattccggg agagtcgcca ccactacaga
     4321 taactgcgat tttcatttta gatcctccta aaaaaggtga ctgcgattct attctcccat
     4381 tagagaaaat gaagcaatca aatgggcaat ggagtcgcgg tcaccttttt catattttta
     4441 tgattagtat tccatttgct tataataacg gcgagtagtt aaagggtggt tacgttcttc
     4501 ttctagaaaa gcactaattc gttcaaagac agtagctaag acgactgggg aaataatttt
     4561 tcgcgtgtct tccgaaatgc caggtaagtc atagtccttt gtatcaaccg ttacgtgaac
     4621 atctgtaaac ttaggaacga aattcttcac gcgttctgtg agaggtcgag aatcatcttc
     4681 tccttctgta atgatgacac ttacacccgc ttcaattaat tcaagagttc catggaagaa
     4741 gtctgctgca tgaacaggac gagtcttaat ccattgcatc tcttctaaaa tacacatgcc
     4801 atagtaatat gcttccgcaa agctatcacc agcaccggtt aaaatatgat atgaagtatc
     4861 tttgtgtttt tttgcaaaag attttgccat tggttccgct tgctctttag cgtgcactaa
     4921 ggcttcaggt atttttttta aatcctcaat ataggtattg tattgattga tatcgatttc
     4981 atttctttgt ttcattaaga agagagcaat cagcagtcct tgaaggtaat aattttctga
     5041 agatgtatca tctaaaacgt cgttatagat agaatatgtt gcagcttttt ctaggggcgt
     5101 tttaggactt cctaccaaag ctaatgtttt gacgttcatt tcattacagt attcgactaa
     5161 ctcaagtgtt tcttttgttg taccagataa agatgggata acaaccaaag atttgttaga
     5221 aaatgtttta ttgggatgaa tcataaattc ggcagcgata acacgatgaa aagggaaagt
     5281 gctacgagtt ctcgcgaatt cgattgttga atcaaaaaga ataccaactc ctccagaccc
     5341 aataaagtaa atttcttcta agtcagatgc gatggattct aaaatattgg aaatttgttc
     5401 atttgttgca acggcaccag cttgagtctt taaaaatctt tcttgatcaa aattaaacat
     5461 aaaaatctct cctttgatta ccaatggtaa tattttgttt gcataaataa aataccacag
     5521 gtaataaaaa gtgtcaaata ttttttagga aaaataccat aggtattgtt aaagtggaaa
     5581 gatgtttata aagaatattg aattttatag tgaaaatcat ttattattaa gtaaaggagg
     5641 tgggttcatt tgaaaacgaa aattttaaaa gaattaaatg atctacttaa cagctatgat
     5701 tttccacaat attttccaga agaatgtaac gcgcaatata ttgcccaaaa atttcaaata
     5761 aaaagaaata cggctagtaa gcatctaaac gaactaatgg aacagaaaaa agttgtgaaa
     5821 atcaatggtc gtcctgttct tttttttcca gtccatacaa ttgaacggta tatatcacat
     5881 tcattagata gttttgagtt ttcttcaatt gattcgttta gagaaaaaat ttcaaagaaa
     5941 aaagcagatc atttttttga tgatttaatt ggtgcaaaac aaagtttaaa agaagcggtt
     6001 caacaaggga tatcagcaat gaaatatcca ggtggattac caataatgta ttttggatcg
     6061 tccggagttg ggaagagtta cttagtggaa aaactagctg agtattgccg acaaactggt
     6121 attattcatg agaatgctcc gttcatcgag ttaaactgcg ctcagtattt taataatcca
     6181 gagttattaa caagtcagtt gtttggccat atgaagggat cgtttaccgg cgccgattct
     6241 gaccatattg gtataataga agcagcagac ggtggaatcg tctttcttga cgaaattcat
     6301 cgtttaccac cagaaggaca agagaaactt tttattcata tggataaagg cgtttttcga
     6361 agagttggag atagtggtcc ttggcgttta tcacatgtta gatatatttt tgcgacaacg
     6421 gaacaggaag aaaatttttt tctagaaact tttcgacgaa gaattccgat tgtttgtact
     6481 ttgcctaatt accaagatag agaaattagc gaacgaaaag agattgtctt ccatttatta
     6541 gagaaagagt ctactctgat caataaagaa atattagttt ctgaagccgc ccttagtttc
     6601 ctgattcgct tagatttgta tggaaacatt ggtgagctgg atggactaat aaaacaaact
     6661 attgcgaata aactatttag tggaagcaat aaaaaatata tcgaaattca tatttctgat
     6721 ttacctagca ggtacttgct aacagaaaat attgagttaa aaaaccaaat tgcgagccaa
     6781 cggttctata tctttagtaa tggtaactat gttcatgatt gtgacgagac ttcaactgta
     6841 actacaaatt tacgaggttt gattcatcgt gtttctaaat attattcaga gtgtcatgat
     6901 gtgaatagaa atagtgaaga gtttcgacgt tttgtgaagg accaaatggc agaatttaat
     6961 gatcgtttta tttaccaaaa aaattcagaa gtcttagtta agtattattt accggaaatc
     7021 caaaatattg ttcaaaaaat ctctcccagt ctttttgttc acctttctgg caatacggtc
     7081 caagctatag ctacctatct cgctattagg gatcaatggg ggtatgggaa agagaatgct
     7141 tcagcgaatg aaattgaaaa gttatatgaa aacctaaagt gtaactattt gacggattta
     7201 aatgtattct tactgatctt cgagaacgcc ctggatacaa cattgactat ttgggataaa
     7261 ctgtatatca gtttgtgtgt tattagtgag accggaaatg aagcgaaaga cattaacgca
     7321 attattttag cccatggata tgcgacagct agtagtattg ctaatgttgc caatcgtttg
     7381 gttaatcagt ttgtcataga ttctattgat atgcctctag atatcagctt tagtgaagta
     7441 attgacagat tacttcacta tatagagtat cgaaagccta aagatggact agtgattttc
     7501 gttgatatgg gaagtttagc tcaaattaag actgaaattg aacaagtaat cgaagttcca
     7561 acaatgatta ttaataatgt tacaaccgaa atggctattg aaaccgcaca actgattcaa
     7621 agtacgagtg atatccaaaa ggttgtaaaa aaattgccgt attctcagtt tgaaaagcaa
     7681 gttctatatc ccatcaaaat tagaaaacgt acaatcgttg tttcctgcaa tactggtttg
     7741 ggtacctcca taaaaattaa agaaatgatg gaaaataatt tgtcgaaaga cttgggcatt
     7801 gaatttctgc catacgaaaa tgaaactctt agagatactc agcaattaga gtttctcatt
     7861 aaaacaaagg atatcattgc cattatcgga acagatgatc cgcgtgtgtc gaacattccc
     7921 tatatttctc ttgaagaatt atttgatggt gaaattggca aactctataa agttcttttg
     7981 agagtctatg gaaaagagat tgctgaggca attaatcaaa atattgttaa aaatagctca
     8041 ttaaaccgct tgattgacag tcttactatt ttagatgccg aaaaagttgt caatcaaatt
     8101 gaggaaagtt taaaagatta tcaaatgagg gtggggaaaa cgttatcatc attgtccaaa
     8161 attaatcttt atgttcatat cagctgtatg attgagcgac taattcgtaa tcagggagta
     8221 agtagttatc cagcaataga tcagtttctt aagcgatacg aaactgaggt tgcttctatt
     8281 caaaaggcac ttagtaagat tgagaaactt tataatatta agattcctat ggaagagatt
     8341 gcatatgtgt gcaacatcat tgtaagttat tgataaaata aagtgacact attcacagcg
     8401 atggaaatag tgtcacttta ttttttgtac gccctttcat ttaagtggtg acagtaattg
     8461 gcacagtatt tgctaataac aaagcgaaag gagttcgggt atgagacaaa tattatgtat
     8521 gagccacggt cctctagcaa aaggaatgat tgaaactttg agtattatcg taggagattt
     8581 ggataatatt gattttcgat gtgcctatgt cgatggaaat aatgacgtag aaatgatcat
     8641 cgatgattat ctaaaggaat ctatgggaaa tgagacgatt gttgtaaccg acatttttgg
     8701 tggaagcatt aataatgagt ggctaagacg gttgccagat ctttctaaag tctatttgat
     8761 ttctggaatg aatttaagtc ttttagtgga tttatattta aaattccaat tagtttcatc
     8821 tgatcagatt gaagaaatta ttgatcatgc aattcaagca tcttctggtt cgattaagtt
     8881 ttgtaatcag ctagattatg agcaaacggt tgatgacttt taaataaagg agggaagaga
     8941 atgattaaat tagtgaggat cgatcatcgt ttgatacacg gtcaagttgc tttaacttgg
     9001 acgaacgcaa tcagtgcgga ttgcatttta gtagcgaacg atgaaatttt gaatgatcca
     9061 attcaaaaga caactttgaa attagccgca ccacataacg tgaaggttgt tatcaaatca
     9121 attcaagatt cgattgatgc aattaatagt gggaagacag ataaatacaa actatttgta
     9181 gttaccaaaa ccatttccga tgctaaacgg ttggcaaatg gggttgaaca aattaaatct
     9241 gtaaatatcg gtagtgttaa ggaaactagt ggcagtagcg ctttgacgca tacaattttt
     9301 gtaacagaag aggaacgagc agaacttaaa ggaatggtct cagagggcat tgaagtgttc
     9361 gctcaacaag ttccaacaga taaggcaata gatttaaaaa aatctttgta ataaaaaaat
     9421 aagggggtaa tttcatggat agtctcttag tacaagcaat tttgcttggt ctcttgactg
     9481 cgttcatcgt aattgactgg atgacaggta cgaataactt atcaagacca atcgtatctt
     9541 ccgtctttgt tggtttaatt atgggcgatc ttaagatggg gattatgatg ggggcaacac
     9601 tggagttagc atttatcgga gcaataacaa tcggagcggc acgtccgcct gatacggtat
     9661 ctggtgggat tttagggact gcgtttgcta ttgcaactgg caagggagca gaatttgcgt
     9721 tgaccttggc attcccaatc gctgcgctat tcttattagt tgataatcta ctaacattgc
     9781 ttgttctacc aatgattgct agaaaggcag atagatatgc tgaaaagggc gaactaaaaa
     9841 atgtgtcgaa aatgcatgtt ttaggtttta tcttagtaaa aagtttacca cgggctttat
     9901 ttgtcggatt ctcattttac ttaggaagtc ctgttatgga acgaatctta aatgctattc
     9961 caacttttgt ccaagatggg attaacattg ctgcaggcat tatgccagca ctaggttttg
    10021 ctattttatt gcaaatgctt cttaagaaag atgtctttgt atatttcgta attggttttg
    10081 cactctttag ctacttacat gtgccgattc tggggattgc aatcttcggc gcatgtctag
    10141 cttatattat agtaaacatg gaaaccaaag ctgcaatggg ttcaagaggg gaggagatgg
    10201 ttgaagatga cttctagtgg gaaagcttta actaaagatg atttaacaaa aatttgtatt
    10261 cggtcatgtg cattagaagc atcatggaat tttgagcgcc aacaacatat gggctttgct
    10321 tttgctatga tgccagcgtt agaaaaaatt tatagtggca atgaagaaga aaagcaaaaa
    10381 gcagctcaaa gacatctaga gttttttaac acagctccgc cattatcaac attcataatg
    10441 ggaattgtgg cttctatgga agaagaaaat gccaaaaatc ctgatgactt tgatacttct
    10501 acaatcactt ctattaaaac tgcattgatg ggaccattag ctggtattgg tgattcaatg
    10561 ttttggggta ccttattagt tatcggtatc ggtgtaggtg cttcattagc aaaagaaggc
    10621 aatattttgg gtccattttt atttttacta atcttcaatg tccctaattt tcttctccgt
    10681 tactttggag ttatgcaggg atataacttt ggtacaaagc tattagagaa cattgaatcc
    10741 tctggcgtca tgaaaacgtt gactcatgct gcctcaattt tgggtcttat ggtaattggg
    10801 ggcatgtctg gaagtatggt atcaatcaaa gtagctggtt ctattggaca aggtgatgaa
    10861 gcaacaaaaa ttcaaagtat cattgatggt attttaccaa atctgctgtc agtattatgt
    10921 gtatttctga tttactggat gcttaaaaaa ggctttaaaa caacttacgt gttattcgga
    10981 atctttatct ttggtatcat agcagccttc ttcggatttt tgacaactta attgaataat
    11041 ctaaataatt gtaaggagag aactaatgtt aaactataat gcaaaagaaa tgaaaaaaaa
    11101 aggcaaacgg atttacggta ttcgtgaaga tgtagaaaaa attgcaaagc aagcttatga
    11161 ttctggaatt agtaatattt tctttactgc ttctggtgga tcggtagccg taatgcaacc
    11221 atttgagtat gtattgatga ctgaatcaag tattcctgtt tactctatga ctgcagctga
    11281 gcttgtctta atgggacata aacagttgaa tgaaaaatct ttagtaatct tatactcaaa
    11341 atctggagat acgaaagaaa ctattaaggc agctgaatat ttaaaagaac gaaacgtgcc
    11401 aaccgttggt attgtaagta aagaagatac accgttagag gctctatcaa cttatgcaat
    11461 caattaccta gacggccgcc ctcaagaaat gccactttat ttcttaatta tgtctatcat
    11521 gaatttgaat ggggaatttc ctgaatacac tcgttttgct gatgaactga aaaacttacc
    11581 aacggctctg aattcagtta gagaacaggc tgatgaaaaa gggaagaagt atgccgaaga
    11641 atttaaagaa gatccttatc aaatttggat tggtagcggg aatttatggg gaatcaccta
    11701 ctcttattca atgtgtgtgc ttgaggaatc tcaatggttg cgtacaaagt ctgtctcatc
    11761 accagagttt ttccatggta ccctcgagtt agtcgaaaaa ggagtttgtg taacactttt
    11821 gaaaactgag ggggaaacac ggcttttaga tgctcgagtt gaaaaatttg cggtccaata
    11881 tacagataaa tttaatgttt ttgatactaa ggattatgag ctaccaggta ttagtgacga
    11941 atttcgaaag tacttttgtg ctccagttat gtgggcagcc ctaggtcgcg tcagtgttca
    12001 tcttgaagat attcggaacc actctttgga taaacgtcgt tattaccgag tagttgaata
    12061 ctaaaagtag gtgattaatt atgacagcgt atgtgattgg atttggcgat aatgttgttg
    12121 attactatga gaatttgaat caaaaatttc cagggggaaa tgcagttaat tttgctgtga
    12181 atgcaaaaaa gagtggtgtt aaagcatact atgtcggtag tctatcatct gatcctgatg
    12241 gcgtgttatt acaacacgcc atcagttctg aaggtgttga tatctctttc tcggaagtta
    12301 ttgacgagcc tactgagcaa gcacatgtaa ctattaaaga tggagatagg gagtttatag
    12361 gtggcgtgcg tggctcccga ttgacacctg ctctctcagc agaacttatt gatttgatga
    12421 agaacagttc attagttcat actagttgcc atagtcgaac agaaacaaaa attaaagaat
    12481 taaaaaaata tgatgttaaa gtttcttttg atttttctga cttagataaa tatagaacgc
    12541 atgaatactt gtcagatgtt tgtccgtcaa tttatattgc acagttttca gtcgctacag
    12601 atgatcaaga ggaaattaat cgcttaatta gtgaatgcaa ggactttgag gttccgtatc
    12661 ttctttttac gcgtggtagt aagagccctg tttttgttga cactcgagag aataagactt
    12721 atgaaggatt cattcgcaaa gttgagtcac ctcatgatac aatgggcgca ggtgatgcat
    12781 actttgcagc ttttgcaagt aattttgtct tatctaaacg tgaaaaatca atgatagaac
    12841 atgttattga ttgttttcac aaaggtgcaa accttgcata tgaaacattg atgattgatg
    12901 gctcctttgg tcatgctaca cctattaacc cttagctttg tgctttgggc ttttattgct
    12961 ggaatttgta tagtagactc atcataacta tatttttgta tgtgaaaagg caagaggcta
    13021 tgatgaaaat aacactggct aattgcatga gggagcatat cgttgttaaa gcgtcattga
    13081 tagtatgaat aaatatctcg ataatattat attgttattt acttaattta ttgattagtc
    13141 aagcaaagat aatcttctgt tacttaacga gactagtagg tacaagcact tcatgttatg
    13201 tacgacccaa aaatattgct gttgattatt tgctgaaatt attgcgagct tcaatttatt
    13261 tttaaaggac ttggtaggct gcgtgatgaa ataagacttg gaaggctgtc taaaccaata
    13321 tatagtagac taaatagtaa aaaagagcat ggtaattgtc tctttgtcaa taagtctaat
    13381 ggtaataaga caagttggag attgagaata tttttattgt gtaacctatt ttgaagcgta
    13441 cttaactagc cccggccaaa atcaaatttt ttcggggtat atcaagggtt tgcgtcaata
    13501 acagaatgtt atttatctat cacgttcctt ggtggcgtgt agagttgatg gttacgtagt
    13561 agcgtatcta ccagacgcgt aaattttctt gcggttaaga cgtgtgctcg tttgtgttta
    13621 tttttgggac ctctttacat ttgctttgat aaaaagcttt atattgagga agatattttt
    13681 ttacagagtt ggaagcttca actaagtagt atctaaaata gcgactcctt tgttttgtca
    13741 gaggtgtatt ttgtgaccga tagttaacag attgtttgcc tttccaacat aagcctgcgt
    13801 attttgccaa ttttgtttga tcttcaaatc gttcaatttg accgatttca gcgattaatc
    13861 cagcggcgtg tacctttcca atacctggaa cactagtcaa atattgatat tctggaataa
    13921 cgacaacaaa ttgctcggtt gctttatcca agtctttgat gttcttttca agcgcacgaa
    13981 tttcacatac aaaaacattt agaacgacat tgatggattc ttatgcaaga ctatctaacc
    14041 gataactcac ggcaattgca cgttgaatcg atttggcatt tttttctgga tctttaaagc
    14101 gacatttcct ttttctttta gtaagtcaca gaaagcttcc aaaggaagca cagccaattc
    14161 atctagcgtg aagtcttctg tcacaagagt aatgacagtg gcactataga gacttgtcga
    14221 ttcatcgcgc atttatcgag taagcgtatt gcatttgtac gttagatttt ccagaaagtg
    14281 ttgttttgta cgagtgaagt tgcttaatga gtcgatagcg agtgcgtgtt aaacgctgta
    14341 aagccacgta cttctcttct ttgataggag aagttgtgaa ccgttgaata cgcaataaat
    14401 cagcaattct taacgcgttg tttcgatcag tcgtatcttc ctcaaacatg cgactgaatt
    14461 gtttcatccg aaaaggattt tcaatcctca caagtgcatt gagttttttt agctctgcat
    14521 cttcatggaa aaacatcgaa ggatgaaagc tgtacatgga cgtttaattc catctcaata
    14581 acgatttgac cgaagtgatt gttttcattg aacacaagaa tcagttctcg tgtcaatgga
    14641 gccctttcaa tgtcattagc aacagaattt tcagtcaata tagatagctg atcgtcgtct
    14701 gttaggaagc aaacgtctaa tttttcagaa ctaacgtcat taccaacaaa taatttcatg
    14761 gaataaaaac ctattttcga tataaattct agaaaatgct tcgatactgt gggattccac
    14821 agaaactcac tgtgtggtca cgacctcgcc taatagaata cggtaataaa agagctaatg
    14881 agttgatagt aaacacagcg ctttggataa cagacttatg aaggtagaca aagctacagg
    14941 actgattagc aaattctcgt tgaatccttt ccatacatcc attgtactct gagaaatcac
    15001 acaataacga aataaattcc ggaaggaata tgttattcaa aaaaatttgt gttttataga
    15061 tactttaaaa gaaacttatt aggcaaaata tattttacga agactgatga gttgtgcaaa
    15121 atcaaatctg agtcagaatg aacttcattc tagctcagat ttttgtttaa tgacttcagt
    15181 cagtttcttg cattacgtga atgaaaatgg gactggtgat gtccaaaccc taaaaagtta
    15241 gaccaaaatc taacttcagg ggggatggta tttttatggg aaaatatagc tttgaattca
    15301 agtcaacaat cgttcaagag tatcttgaag gagaaggtgg attaggatat ttagcaaaaa
    15361 tacaaggagt gagatcaaaa aaaggtacac ggatggatca atcaaaagtt agaccaaaaa
    15421 atctaacttt tgggggtcgt tatttgtatg gcaaaatatc cttttgaatt aaaactaaaa
    15481 atcgttaaag aatatcttag tggcgtgggc gaatatcggc atcttgccaa caaatacggt
    15541 atttcaagca agtctcaagt aagtgattgg gtgaatgcct atcgtgaata cggagaggaa
    15601 ggtctattga aaaagcatca aaatcagaaa tattctgttc aatttaagtt aaatgcgcta
    15661 gagttatatc aaacaagtga gatgtcctat cgagaagttg ccagcacttt agaaatgaac
    15721 aaccctgcgc ttattgccaa ttggatgcgt aatttcagag aagcaggtat tgaggggctc
    15781 tcaaaagaga aagggcgacc acttactttg actagaaaaa aagaaaacaa aaaagaaaat
    15841 acaacaactg aagaacgcga gcgtatcaag gcattagaaa agcaagtccg atcccttcaa
    15901 attgagaatg cctttttaaa agagttgagg aagctgcgaa aacaggaagc ccagcaaaga
    15961 cgcaagaatc aatcgcacga atcatcgcca gcctccgagg atcattcaaa ctagttgagc
    16021 ttcttgaaac attgaaattt cctaaagcaa cctatatgta ttggcagaaa cggtttgaca
    16081 gaccaaaccc agaccaagaa attgaagaaa aaatgcttga aattcgcaag gagcataaag
    16141 actatggctg tctgcgacta aaaaaagaat tagagaatca agggattcat gtcaataaaa
    16201 agaagattca acgtctgata aaaaaactag gtatcgaagt aaagtcttac actcgaaaat
    16261 ctcgacggta caattcttat catgggaagg ttggcactgt cgccaaaaat cgtattcatc
    16321 gtcggtttta tacaaatatc tgtcaccaaa aaattacaac tgataccaca gagtttaagt
    16381 attatgaagt agacaccaca ggtgtcgttc gtcagaaaaa gctgtattta gatcctttca
    16441 tggatttcta caatagtgaa attctatctt atcggatttc tgaaaaacca aacgcactag
    16501 ccataatgga aggattagaa gaagcaatcc agatgacaaa tgattgtcca tttcgtagaa
    16561 ccttccattc agatcaagga tgggcctatc aaatgaatgc ttataagaat aaattgaagc
    16621 agcataaaat cttccagagt atgtctcgta aagggaattg tttagataac tcacctatgg
    16681 aaaacttctt tggtttatta aagcaagaga tttttcatgg agaagtctat cggagtttag
    16741 atgaattgaa aacaaaaatt gaccaatata tctattatta caaccataaa cgcatcaaaa
    16801 agaaattaaa ttggcgaagt ccggttcagt ttcgagaagc tgtaaaaaca gctgtctaac
    16861 agttaatttt atcgtacaaa aaaggagtgg atttctccac tccataaaag tctaactttt
    16921 tggggtcgct acaaatgctt atcgagaatt tggagaagaa ggcctcttgc gtaagcgaaa
    16981 taagcgaagt tattctgttc aattcaagat agatgcgata gagttataaa aaacgggtga
    17041 gctatcctat cgtgaagtgg cgaatcattt agggataaac caacctgcgt tagttgtcaa
    17101 ttggatgaaa atttttgttc aaaaggattg cacgggctct caaaaatgaa agggtcctcc
    17161 tccattttgt ctaagaaaga ataaaaggaa gaaacaagca aactgacgcc taaagagcat
    17221 aatcgtatca aagaattgga aaaataagtg cgtttccttc agattgagaa taccttttta
    17281 aaagaattga ggaagcttag aaaacaggaa gtctaacaaa gacgaacgaa tcaatcgcac
    17341 gaatcatcga caacctccga ggatcattca aattagttga gcttcttgaa accttgaaat
    17401 ttcctgaatt aacctttatg tattggcaaa gacgatttga tcgaagaaat tcagatcaag
    17461 aaatcgaaga ggaaatgctt aaaataagaa gtcaatataa agattatggc tatttacgta
    17521 tgacaaagga attgtgggac cgtgggttcc atgttaacaa gaaaaaagta caacgtttga
    17581 ttcgaaagct gagtattgaa gtacgatcat ttacgagaaa atatcgccgc tataatactt
    17641 atcgtggaag aatcggcatg attacaaaaa atcgaattca tcgacgcttt tacacaagca
    17701 actgtcatca aaaggttaca acagatacga cagaactaaa atattttgaa atggataaat
    17761 acggtgccaa tcgtgaaaag aagctgtatc ttgatccatt tttagatatg tacaacagtg
    17821 aaattttatt ttatcgcatt tctgaaaagc caagtgcgtt ggctatcatg gaagctttag
    17881 aggaagctat ctgcgcaacg gaatgtatct atcgtcgaac ttttcactcc aaaaaggatg
    17941 gacctaccaa atgaaagctt atagtcataa gttgaaagaa cataagatct tccaaagtat
    18001 gtcccgtaag gagacctgct tagataattc gatcattgag aacttcctta gtctattaaa
    18061 gcaggaaatt tattatggaa gagactatcg tatctttgaa gaattgaagc aagccattga
    18121 tggctatatt cattactaca accatgagcg tatgaaaagg aaactaaact ggcagagtct
    18181 ggtgcaattt agagtaatag cattcaaagc tgtctaaaat catcaagaaa agcaaagaaa
    18241 aacggagtga attttctcca ctccgaaaac atctatcttt tttaggtcac tacagaatca
    18301 attctgattc atcagaccca taaattatag atcctaataa tttataccat gctcttttta
    18361 ctcatattta catttatctt tgggtatttt atggtttaag ttgatgtctg atctagtttt
    18421 attctggatt aattaaccta ataatccaat ataaactcca acaatactaa agacgaagat
    18481 agcaagtata atccaaagaa cctttacttt tttctttaat agaaagtaaa caaagaatgt
    18541 tagccccaat gagagaattc ctggaaaaat atcatcgagc atttgctgaa catttatttc
    18601 tccacctttt gatttaaata cggcgggaat agtaaagcgt accagagatg aggtcatggc
    18661 tccaattgac attaaaccta cgatagatgc tgctaacgag aaactttcaa ggtaattgtt
    18721 ctcaaatgct ttttcaatgg cgtttgctcc catccgatat ccaatacgta agcagccata
    18781 tctgccaaga aaatgtaaca gcgtataaat tgaaaaatac aatattggac ctaaaatgtt
    18841 tccttgggca gctaaagata agccgatgcc agcagcaata acgcgaaatg ttccccagta
    18901 aaaactatca ccaataccag ctacaggccc catcaatgca gcttttatcg atgaaattgt
    18961 ttcagtttca aattgatctg tttttgcatt ttcttcttca agtgctaatg acatacccat
    19021 aataaaggtt gaaatatgag gcgttgtatt aaaaaattcc gtatttcggt aaacagcttc
    19081 ataatatttt tcatcattcc cttgatatat tttgtttaaa gcaggtaata tagaaaaact
    19141 atatcccatt ccttgcatat cagtgtatga ctcggatccc tgtaaagcaa atgaacgcca
    19201 gaaaaccttg tttatttctt ttttagttaa tttagaatct cccataatta tcactctccc
    19261 tttaaatatt tacaggattg cgtttagttt ggataactaa taaagcaacc ataattgcag
    19321 caacagctac accaactacg gggactccta aatatgccgc taaaaggtat ccaatgaaaa
    19381 aataaggaac tgattttttg tcaatcattc cttgaattag catggcaaat ccaacagcgg
    19441 ggagtaaacc agaagctacg gtgaaaccgg tcattaattt ttctggcata atatttacaa
    19501 aactttctgt agcattggca ccaaaatata ctactaaaaa tgtaagtact gcggaaggta
    19561 agcgaacgat taatggaaaa aaatgccact tctgaaaaga tgataatttg cggttttcaa
    19621 ttgcttttct accttgtgaa acggtaaagg agttaatcgt aaaagccaac atgtttaatc
    19681 cttgtgccaa tacagcgaaa ggcatcgcca atgtaacagc tacatcagca cctgctccac
    19741 tttttattgc tagagccgtt gcaatagtac cagctacacc tacatctggt ggtagtgcag
    19801 caccaatcgt tacaatgcca ataaacattg cttctaatgc tgctcctatc aagatgcctt
    19861 gatggagatc ccctaagata agtccaacaa caggtccaac tattatcggt cgattcatca
    19921 tagatgcccc aaaatatctt tcatctattg tcgttaaata cccaactatg ccaattaaaa
    19981 tgcattcaat cattcttatt ccccaccttc taataaatct tcgcttttcc agttggagta
    20041 gcctgcataa ttaatttgaa gccggactcc tttaattttg ctaagtagtt tttgtcttct
    20101 gatgtgatag ccacatactc gttaactttc tcttttccct cggcgtaccg taaaccaccg
    20161 atattaattg aatcgacttc ccctgggata gcgtttacaa tttcaaatgc gcttttaggg
    20221 gaactagtga ctatcatcaa attttgattt ttcctttttt caaaggtact taaaaaatct
    20281 gctgaagtaa taatatctag tcccgttgat acaggttttg ctaatgataa aatcatttgt
    20341 ttcattttgt cattagcaga ggcgtcatca actacaataa tgtagtcagc agatacggac
    20401 ttagtccaag ccattgcaac ttgaccgtgg atcaggcgat cgtcaattct taatagttta
    20461 atcattatct tctacctcca ttaattctga acagtttata atgctctttt ggctttcagc
    20521 aataatcatg gaaatttttt ctctcaattt ataatcttca atgttcatac ttaattccat
    20581 aattaaggac aaagtcatac ctgcaattac tgtaattttt tttgttaatt ttttttcgta
    20641 aacataattc atccaatgat tatttacgct accaccaagt aaatcagtga tgacaaggac
    20701 tttatcagtt ccatcgagaa gaatattcgt atctttttca atatcatagt tatcgtctgt
    20761 gtatgcagtc attactttta tgaatggtgc agggccaagg atatattcga ctgtctcttt
    20821 cattcctttc gctaaatttt tgtggcttgc aagaataatt gtgtacataa tccacctcca
    20881 tttatttata aataatatac cattggtaat ctaaatgtca ataaattatt tcgtattaag
    20941 aataaataaa atacctttgg taattagtgg ggcgaatcta aaaactttaa ctaaaattct
    21001 cttttgtaaa tttttttgaa cgcggctatc gtggtgattt tttatttctg tttgtttaat
    21061 gaatttgtaa attaggaggt gatttttgtg atggtgtaaa caaagcctat aaaaatgaag
    21121 taaagcattg tgttttgtcc agatgtcaaa tcttttatgt atcggttgta tgtatagtat
    21181 gttacaccca aaatagataa cccaagtcca aatggagaga cagatgttct ttatattact
    21241 ggcgaagaca tgaagtattc ttataaaata tctaaaaatg agtataagtt taaagaaaat
    21301 aatttatcta tataaactat tctgctttga ttagcaagtc tttcaatcgg taaaatatta
    21361 tttgaataga tgggatatgg tttattattt tctaaatgtc aaattaagtt agacaattgc
    21421 tcctcactta tgtaactcaa aaatacttct aacgatgttc gataatttaa agatttcctt
    21481 ggtatatgat ttcttttgga ggcaaccgcc gccacaaatt tttggtcaac ctgattgaaa
    21541 tccattgtat taggaagtcc gtctttacgt aacaatccat tagaatgttc atttaatccc
    21601 cgttgtgaca gcgttccagg atctgcaaaa taaatagaaa tatcgttagc attactcatg
    21661 tttttccaat tcgaaaattc ttttccgcaa tcaaaggtaa tggatttgaa caagtttcgg
    21721 ggaagctttt gtagccagtc agttgtcact ttttcaatat ctagtgcttt ccgtccttcg
    21781 ggttttaaag taataatcac ttttgacaag cgctcaacca gcgtgatgac agcactttta
    21841 tgatggacac ccacaatagt gtcgccttcc aaatgtccaa attcctgttg aaattcagga
    21901 tagtccgtga gacgttctga aatattccgt ttgaaggctt gtttccctcg acgttcttta
    21961 tgcccgttgg gtttccgttt tcctttcatg ggtagtttcg agcaatcaaa ttagtttgtt
    22021 ttaaacttgc gataaagggt tcgaacagaa catgaaattg aaaactcagc acgaccgata
    22081 atcacatcgg gtgtccatcc ttgcgccacc ttgtttcgga tatacgcatc ttgttctgct
    22141 ggcaaacaaa tgggtcgtcg gccgcaccgt gttttatttt tttgatattg ttggtaatag
    22201 tcatggatag attggccttg tttcaggaag ttgtacacat tgtagatggt ctgtctggaa
    22261 cgatttgagg tcttagcgac tacggtaaca gattgatgca tattgaaata ggcttctatc
    22321 atcacgagtt catttgttgt aagatgggta taggtcattt gtcttcactc cttataattc
    22381 tttggtcgga actattttga gtgtagcaca aatgactttt ttagttgtct agcttaattt
    22441 tacaatctgc gtttaataaa ctctcagtgg gatagtttga ctccgtatat gactccggtt
    22501 gatttgattg aattcagatg attatacata ctataaattt ctctattatg ttgccatttg
    22561 atttgaataa tgctgaaaga aggattttag tctataacga acaagggaat aaaaccaata
    22621 aaaaaagata tagaatatca atataacaaa aagagattgt gacataattc tctgaaaaaa
    22681 gctctagaaa tgacgagtca ttcgtcattt ctggagcttt ttaggtaaaa taaaagagta
    22741 cgagaggata ctcgcactct aaatcattca acccttgaaa ggatcaaaat catgcataca
    22801 aattataaca tgaatcaact cactttagat atcacaactt cttattccaa aagaagatag
    22861 caccgctggg tttgtcaatg aactcgttga aacccttgaa atcaacgagc cgtatctttt
    22921 tggccgccct aggaattgtg atttgagtgc catgttaaaa ttggttcttt tcgcatattg
    22981 aaaatgattg aagaggacta tcggtattac aaaagacaat ataaccagca ggtgaaaaaa
    23041 tggagaaggt aattccgaaa aaagcttctt ttggcgattg ggaataattg ttggtaatgg
    23101 aggaataaaa tgaatgttta tgcagacgtt tgatgtctac atcaacatcc attcttaata
    23161 ctcgaaggtt cgttgttgaa aaaactaact tttcttcaac agaggattta cgtgcaaatc
    23221 aagccgagta tttcttcaat aatctttgtt tgacgaaact gtataaggca gtaaagaaag
    23281 caagtcctaa tgttaagtag cccaacggaa cacaaaagaa cgctggttca atcagcattc
    23341 cgcttgaatc gaggtaagaa ccgactagga tggaagttga aaataacaaa atactcaaga
    23401 aaagaaatat acaaggaata atgaattttt tcatggtgtc tccttctttg tttttctaga
    23461 ttatatagaa tagaacctag gaaaagataa gtgtgacaaa attgataggt gtgaaaggca
    23521 ttgagatatc aaccagcttt atcctttgga gtatgctatt gtgattaatg agacagagga
    23581 tgtgggacca gacgatactg aatcaacgga aattgttcta aaccaccatc aaatagtagt
    23641 ttttctagta tttgaaggtg atttttttat gttcgaaagt aactgtaaaa aagataaata
    23701 atcggcagtt attctttcac ataagtaggt tggatgcagg tgagagaagt ttattgtatg
    23761 agaggaagat tggtaatcta actatagttt tataactaat atcagtttaa gctcgattat
    23821 ttttgtttca aagtaaaatt ggaacagaaa tatagaatag acatattgta gccgatagtt
    23881 tattatgctt ctagacacgt tgaactggag gggaaaatga aaaagagcgc taaagatcga
    23941 gtttttgatg agctgatacg actaacaggg aatatgtctt ctgtcactgc cgagaaaatt
    24001 tcgaagaatc taggtatctc tcgtcagaat gccagccatt atttgacgag attagtggaa
    24061 gataaaaagg tcgagaaatt accgggaaag cctgttttgt ggaagccttt agatgaatat
    24121 gcggttgtag ataatacgga gcaaataaac gaagcctttc attctgtggt gggtcatgac
    24181 ggaagtctga gagaggtcat tcaaaaatgt attgcagctg tcaaatatcc gcctaacgga
    24241 ctcagtgtat taataaatgg agccacgggg gttggaaaaa gttttttagc cacaaaaatt
    24301 tttgaatacg ctatccacga gcaaattatt gaagaagatg caccatttgc tattttaaat
    24361 tgtgccgatt atgcggacaa tcccgaactg ctttcggcaa cactgtttgg atacaagaaa
    24421 ggggccttta cgggggctga gaaggataca gaggggttat tggcaacagc caacaatggc
    24481 tatctttttc ttgatgaggt ccatcgtttg tcgaaagaaa atcaagaaaa gctctttgtt
    24541 tttattgata ctggaaatta tcgtccagtc ggtgaaaatg taaactggca ttctgctaag
    24601 gttcgtttta tcttcgccac gacggaaaaa agtgaagatt atttattaga cacctttgat
    24661 cgacgtattc aaatcagtgt tatgttgcca acttttgaag atcgtcccat tcgagaacgg
    24721 ttagagctga ttcaattatt ttttcaaaat gaagcggata ttttacaaaa agatattatt
    24781 gtttcaaaag aagctttgtc tctaatgtta tctcatccct ttagtgggaa tattggtaag
    24841 ctgaagaata tcattaaaat cagttgtgcg gatgtgtaca gtcgaacacg ggaaga
//
LOCUS       DAPBBV010000043        24579 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.043, whole genome shotgun sequence.
ACCESSION   DAPBBV010000043 DAPBBV010000000
VERSION     DAPBBV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.043"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(153..551)
                     /locus_tag="RD486_002121"
     CDS             complement(153..551)
                     /locus_tag="RD486_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HDT7663842.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(548..1321)
                     /locus_tag="RD486_002122"
     CDS             complement(548..1321)
                     /locus_tag="RD486_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDT7663843.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1318..2001)
                     /locus_tag="RD486_002123"
     CDS             complement(1318..2001)
                     /locus_tag="RD486_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDT7663844.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2168..3055)
                     /locus_tag="RD486_002124"
     CDS             complement(2168..3055)
                     /locus_tag="RD486_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7663845.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3052..3921)
                     /locus_tag="RD486_002125"
     CDS             complement(3052..3921)
                     /locus_tag="RD486_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7663846.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4058..5344)
                     /locus_tag="RD486_002126"
     CDS             complement(4058..5344)
                     /locus_tag="RD486_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7663847.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDVE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5617..6195
                     /locus_tag="RD486_002127"
     CDS             5617..6195
                     /locus_tag="RD486_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7663848.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPMKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6195..7124
                     /locus_tag="RD486_002128"
     CDS             6195..7124
                     /locus_tag="RD486_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7663849.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7121..8857
                     /locus_tag="RD486_002129"
     CDS             7121..8857
                     /locus_tag="RD486_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7663850.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="RD486_002130"
     CDS             complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="RD486_002130"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDT7663851.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9753..10262)
                     /locus_tag="RD486_002131"
     CDS             complement(9753..10262)
                     /locus_tag="RD486_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDT7663852.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="RD486_002132"
     CDS             complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="RD486_002132"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDT7663853.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11563..12654)
                     /locus_tag="RD486_002133"
     CDS             complement(11563..12654)
                     /locus_tag="RD486_002133"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDT7663854.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="RD486_002134"
     CDS             complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="RD486_002134"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDT7663855.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="RD486_002135"
     CDS             complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="RD486_002135"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDT7663856.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="RD486_002136"
     CDS             complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="RD486_002136"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDT7663857.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16617..17591)
                     /locus_tag="RD486_002137"
     CDS             complement(16617..17591)
                     /locus_tag="RD486_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HDT7663858.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17572..19455)
                     /locus_tag="RD486_002138"
     CDS             complement(17572..19455)
                     /locus_tag="RD486_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HDT7663859.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19473..21698)
                     /locus_tag="RD486_002139"
     CDS             complement(19473..21698)
                     /locus_tag="RD486_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDT7663860.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21813..22847
                     /locus_tag="RD486_002140"
     CDS             21813..22847
                     /locus_tag="RD486_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7663861.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22914..23927)
                     /locus_tag="RD486_002141"
     CDS             complement(22914..23927)
                     /locus_tag="RD486_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7663862.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYWGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24005..24193)
                     /locus_tag="RD486_002142"
     CDS             complement(24005..24193)
                     /locus_tag="RD486_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HDT7663863.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7066 a         5339 c         4398 g         7776 t
ORIGIN      
        1 agcatatttt gaaaagaaag tctgatgctt agagtagaat ttcataaaaa tttactattt
       61 cataagtatt cacgagaaaa atgcaaacaa aaaagcggaa ataacgctca tccgccttct
      121 tgtttgtgtt tatttcctct tcaaacgctt gtctatgatt cagacttttc tctatcgtta
      181 ttttcatcta aaagttcttg cattccgata atttctcgat attgatgaat cttagtgata
      241 ccaatgactt tgtctacatc aatactaaaa caaataccat tacctggaat atcgatgttg
      301 atgccttgac caatcgcatc cattacttta ttcgtcaaac tatcgggtac taatgtcaac
      361 acaatatctt tttctggcga aatgtccaaa cctaaaaatt tccctgaatc atgtacacca
      421 gaacctcttc catgtaagat cgttccgcct gctgcacctg cttcttttga aaagtcgata
      481 acatcttcgc ccattcctcc gtcaacgatc gtcacaatca tgtgaagatt caatgctaca
      541 agatctttca tttgctttcc cccaattttt gcaatctttc tttttcgatt ctgtcttttt
      601 catcttttcg tttataaata tatcctagta ctaaagtgga taatattggt gtcaatgcaa
      661 tcattgcaac cacaccaaac ccgtcaatga tcggatctct tccttcaatt tgtgcagcga
      721 ttgccacgct cattgataaa ataaatgtcg aacacatcgg gcccgttgct actccaccgt
      781 tatcaaaagc cattgctaaa aagatcttgt ccacttttcg tcctaaaata aatgctagcc
      841 cgtatcctgg gatcaagaaa taataaagag agaatccgac gagcaaacgc cacatagaca
      901 atcctactgc tgcgccgatc ccaattgaaa ttaccatcag catgattttc gatcggattc
      961 tcccctcgct caattcttca acctgtttga tcattacatg aatcgccggc tcagcaaacc
     1021 ctactaagaa ccccattaaa aagccaaggg gaaccagtat ataattgtaa ggcaatcccg
     1081 caatagcact gcctaaatgc tgtcctaccg gtacataagc catattgact ccgtgcagga
     1141 aaaggatcaa cccaatagtc gttatcaaga aacctttcat aatgtcaaag aaacgctttt
     1201 tgcgcatacg aaaactaatg atattcatta aaacaaatag gattacgata ggtgccactg
     1261 ccaaaatgac ttccatggta acgatttcga ttccatctat cacttgctgc cagaaactca
     1321 ttggaagatc acccccaaaa tcatcacggc aagaatcggc cctaacgaag caataccgac
     1381 cattccaaaa ctgtcatttt catttttctt ttgtttgatc atactagtca tccctccggc
     1441 aagggccaag ataaatggaa cagttactgg accagtagtc actccccccg aatcaaaagc
     1501 aatcggcata aattcggaac tggtgaaaaa tgaggcgatc aaaacgccta tgtagcctat
     1561 agccatcaat tgataatagg atagcttgaa tacgacccga agcagcgcaa aggctagaaa
     1621 tactccagtg ccgacgctga cgatcccaat cagcaacact ctgccaatct ctccgtcaga
     1681 tatatcatat acttgttgtc ccaaaacttg cacggaaggt tcagcaatcg tgatcacgat
     1741 cccgatagca aatcccaaac tgaccaaaac ggtcaaactt ttctttttga tcatatattt
     1801 ccctactaga tctccgactt ccatcataga ataatctgct ccaaacaaaa agagcgtcat
     1861 tccgatcatc atgattgccg caccaaccag aaatgaagcg aggtcttctc cttctaacgg
     1921 tgcaaaaaca aacgttaaaa tgacaatcag gacagtcatc ggcaatatag cagcaatcac
     1981 ttctttaaaa ttttttagca tgtatcctcc tcctttactc tttaagttta ccttaaaatg
     2041 aaagagtttt cgagcacaaa cttaaaacgt tatcatttaa tttttctcaa cataaaataa
     2101 cacacgtccc aaaagtatct ttttacttgg aaaaatgact ttgaaggaac gcgcttattg
     2161 tgttttttta ttttacagag ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa
     2221 atacgatggc agttggtaaa gtagcgatga ctaatccagc catgatcatt ccatagtctg
     2281 gtgtatagga agcacccata gcagataaaa caagcggaac cgtccgttta tcaggagatt
     2341 gcaaagctac taagggccat aaataattgt tccagctact catgaatgtg atgattgcag
     2401 ccgcggcata ggtattttta gccgtcggca tatacactct aaaaaaaata cttagttctt
     2461 ttagaccgtc taatcgagcg gcttctacta gatcttttgg aaaagattta acattttgtc
     2521 gaaagaagaa gatcaaaaaa gcagtgctaa cagatggcag gatgacaacc aagaaactgt
     2581 tgattcccaa aaccgttccg ttcaattgtg aaaacattcg atataaaggg atcatcaatg
     2641 ccgcaaaagg aaccatcatc gatagcagta gaatattgaa aattaggtct tttcgtttac
     2701 tttgataaat ctcaaatcca tatcctgcca ttgacgaaat cagcaatgca aacacagtgg
     2761 tcaccaaagc gatcatcgct gaattccaaa gggaacgagt aaaattcagc tcattggaaa
     2821 acaaattttg aaaattgatg atcaagttac tgccaatctt tatttttccc gatgtgatat
     2881 ccacgggtgt attcgtcatt cccaaaacca tccagacaaa agggaaaatg gaaataaatg
     2941 ataggatgct taatgctgta tactttaata ctgacccaat tgtcgaacga agttctaatg
     3001 cttgtttttt gacgttgggg cgttcgattg tttctttttc taccatattt ttcatcgact
     3061 ttctcctcct actttcgttt ggattatcga caatatcaca ataaaggaaa caataacaaa
     3121 ggaaactgct gccgcatatc caaaattagg cgtgaattta taactcaaat tatagatgta
     3181 ttgagatagg gtggtcgttg catttgctgg tcccccgcca gtaatatttt gtacttcatc
     3241 aaaaagctgc aatgtcccga tcgtcgaagt aatggaagta aacaaaatga ttggttttaa
     3301 atttgggatc gtcactttga taaactgctg ccatttagaa gcaccgtcaa tagatgctgc
     3361 ttcataaatc tccgaatcaa tattttgcat gcctgaaagg aaaaaaatca tattgtatcc
     3421 agtccaacgc caagtgatcg aaagaatgat cagaactctc gcccaaattg gatgagtcaa
     3481 ccagccaatc ggtgtgtcaa tcataccaat gcccaacaac aagttgttta caaggccaga
     3541 ttgagaaaat agacttttca tgatcagaga ataactgacc atcgaagtga tacatggaag
     3601 aaagatagcg gttcgaaaca accctttata tttcaacttt ttatcattta aaaggttgga
     3661 aataaaaagt gctagaaaca acatgatcgg tacttgtaca agtaaataca ggaatgtatt
     3721 aaaaaaagct tttttaaaag ttgcatctgt caacatccgc tgataattac ctaacccgtt
     3781 aaatgtcata ttgacagggg gaccactttg aaaagacgtg atcaaagcca aaaccatcgg
     3841 aataaaaacc atgattgata tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt
     3901 gaataaatct ttctgcttca ttcttttccc tccaattcta tcattgatta tctacatgaa
     3961 aagacaagaa agacaatatc tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct
     4021 gatgaaaaag cgaagaaatt cactttttta ccaccgatca attagccaat tgtgcttcta
     4081 cttgtttttg tgtatctgct agtaccttgt ctgtctcttc tccattgatg attcgatgaa
     4141 gagcttcagc tacgactgct tcaattgcat aggtctcatg tccgtaattc acttctggta
     4201 tttcagatgt ccatgttgaa aaatcgtcaa agatcttttg accactgtaa aattcagaag
     4261 cttcttgata agcttcttgt tcattcgcgc taagcatcgt agatactagt ccgatttctt
     4321 tcgcaagagt gcccatcagt tcttcattcg aagcaaacgt tgcttctagg aaatctttcg
     4381 ctgaatcttc tccagctact cctttgatca cataccagcc agcgccgcca aggttagaag
     4441 cttgcgcttt ttgcagattt tctggaagtg caggtattgg tgcaatcttc cattttccag
     4501 attggttttc tgctccttgg atcgttgaag aataccaagc gccagttggg ctagaagcta
     4561 ctgctcctga ttgtatcgca gttactccag cattccagtc agaggtttgt tcgactagat
     4621 cttctttcaa aagagtggca aacaattcaa gaccatactt taaagatgca ttgtcttgga
     4681 tcgtgactgt ctccacatct tcagatgtat accattctcc tgcctgttgc ataatcatcc
     4741 ttactcgacc aaggtcagaa ggattgactt cagcgatttt ctttcccgtc ttttctttga
     4801 catctcgcgc tacttgaata tactcgtccc acttcagatt ctccatatcc tcttctgtat
     4861 aacctgcttc tgccatcaga tccgtacgat agaagtttgc tgttacgccc gaatcgaaag
     4921 gaacaccgta tattttatct cctactttgt ttaccgcaaa tttatacggt gcaaaatgat
     4981 cttcctttac aatagcagac aaattagcga atgcatctgg ataagaagtc aaatagcctt
     5041 gtatcctata atcttcaatc aagacgatat tgggcaatcc ttctgtattc ccgctcgcta
     5101 aagcggtgtt cagtttctga acgatatcat cctgagacat cgtaacaact tctatctctg
     5161 tttcttcgtt ctcataaact ttttttgctt cattcactgc tttgatattg aatgtctcat
     5221 cccacgccca gacagtgact ttttcttctt tgtctgctgt actactagca cttccgcatc
     5281 ctgttaagaa acctgatgct gccgctaaac aaacgactcc agcaattaac tttctgatgt
     5341 tcatttttat ccgctccttt tccatccatt agttgtttac gtttgctaca ttcatcatac
     5401 caaaatttga aaacggtttc tttattattc agatacttca aaaatttctc ctaaaataat
     5461 aaaaaaatac aaatcaacta tgacaaaagg aataatctta gcatctagac caaagatcga
     5521 aatggtgagg tttctttaaa ataaaaatat ccttgcattt tctcctagaa ataagtattt
     5581 ttaaattaca agactattct taaggcgggt aaaaaaatgc caatacgcgt aattcttatc
     5641 gatgatgaac agacgatttt agatggaatg aaacagttga tcaattggtc tgagcacggg
     5701 tttcaattaa tagggacttt ttccagtccg atgaaagcgc ttgatttttc tttggtacat
     5761 gcaatcgata tcgtggtcac agatgtaatg atgcctgaat taaatggaat cgaattatcg
     5821 cggctattaa aacagcaaca acctgaaaca cagatcctta tcctctctag ctatgatgaa
     5881 tttgatatgg ttaaagattc ttttaaagaa ggcgtcgctg attatctttt aaagcctcga
     5941 ttgagtcctg atttttttct aaattcctta actgccgttt cacaaaaaat caaaaaaaag
     6001 cccaacaaaa gcccaatcac caatcgttat gagcagatct gcgagaatct ttcacagcag
     6061 attgctggac aaactcgtcc attgcttgac cctcttcttt ttgaacacac cttgtttttc
     6121 tgttatatac cgaaaaacgg ccattcagtt caaaacaagg ctctaaacaa aaacagtcga
     6181 tcacccattc attgatggat agcgacgatt cgtttactat ttatcctgtt tctacctttt
     6241 cggaagaatc cggctatgta atcaatactg attccaaaga tacacttagg aagtttgttc
     6301 aaaagtttcg tcaagaagtt tttccaggtg atttttttgt tgtttctgat tcttttgcaa
     6361 tccaagatat caatgaaata ttccaagaga tcagaaattg caccaaagga caacgtttct
     6421 atcataaggg aaagaacctt gcttatcagc atgaacttct tccgttatta accaaccacg
     6481 agcagcaagc aagtagttat ttaacaaaaa tcgttcataa agactacgct ttagctgtca
     6541 aagaacttga gaatttcttc acgacgatat tggaacagcc tattgatcca gcttatttga
     6601 aacatgaggc aatcaatcgt ttctatgcat tactcaacgc tttggctgac gagcatgttg
     6661 ggaatgaaga actttctttg ctcaagatcg cccttccttc tttattagcc gatgctgagt
     6721 atttcgaaga tttttctatt cttgtcaaag aaacacttga gaaactcacc cacttttctg
     6781 caaatgcaaa aaaagacaat ttcgatatct tgactttgat ctacgagttc gtccaggaaa
     6841 attatgagaa agaaatcaat ttacaacttt tatccgaaaa atatcatttt tcatatagct
     6901 atctctcagc catctttact gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag
     6961 tccgtatcag taaagccaag ctctttttga cggaaacacg gcttactttg acggaaatct
     7021 gtgagaaagt cggctatacc gaactgggtt atttctccag agtttttaaa gaagagacag
     7081 gaatgacacc ttctcaatac cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga
     7141 gcatgaactc tttgccaaac ttctgttcat tttgttcatc ggtctttttc tgcaagccat
     7201 cgtcatttct ttgtttattt atcatcgatc aagggatgcc tatatccagc tgttcaatca
     7261 atcgaatgat gtggtactaa aaaagattca atctgaattt gaaagtttga atgatacaat
     7321 cgagaataca ttagccgctt ttgattctaa tccagctgtc aaaagctatt tttccaatga
     7381 tccagcccaa catatggaac agcttcagca actaagaaca atccaaaaaa tgaatgactc
     7441 tctttcaaaa atccatccaa tgatcgatta cgatgtattg atctttggag aaaatggaag
     7501 aacttttgtc ggaaacgaca tgctcactgc cgtatctgcc gattcttttt ttcaatctgc
     7561 gattgctcag agagtgaatg aacgtgctgc tgatacacaa atgctttttg cacaccacgg
     7621 attgactctt cgcgataaga aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac
     7681 attgaatcac gtttacggat atgctgtttt atcgatctca tccaagcaac tagcgaatct
     7741 ttttcaatct gtagtaaatc ctgagatatc gaagatctcc ttcatgaacg aagaacagac
     7801 gatcatcgca tcaaatgaag aaaatacaat tgggagccga tcaatgattt tcaaaaaact
     7861 aacagtaggt gaaacaacga tttcaaatgg acagcagttg acccgtcttc ctctgtaccg
     7921 ccaggattgt acattactca gtcaagtcga tcttcattct ttatctaacc aaatgggcgt
     7981 gatttttccg attattttgt ataatatcgt gacacttgct tttgctggct cattggtatt
     8041 tatgtatttg gatcgacaca caaaatcgat ctaccgcttg attgattcgc taaaacggct
     8101 agaggaagat ggcttaaaag ctactgttcc tgtacaagga agccatgaag tccaattgct
     8161 agggaatacg atcaatcaat tgctaagtaa tgctcagcat cattatgaac agacgatcca
     8221 agacgaaaag aagaaacgtt cgcttgaaat ccaaactatg caagcacaga tacagcccca
     8281 ttttatttat aatacgctga ctagcttgaa atttttgatt tggcagaaaa aaacagatga
     8341 agcagttcaa ggaatcgaca gtttcattac tttactaaga agtacgattg ggaaaaaaga
     8401 agaagtgatt ccagtcaagg aagaaatcaa aagcgtacaa agttacatcg atcttttgag
     8461 tatgcgatat ggcgaaagaa tctcggctaa aataatgatt cctgatgaac tgcagtcatt
     8521 atctatgccg aatatgatcc ttcaaccaat tatcgaaaac gcctatcttc atgcttttca
     8581 caataaaacg caaggattca tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt
     8641 cgaagtgatt gataacggcg atggcttcga tactgaaaat accaaacaaa aaaatgatca
     8701 tttttcagga atcggcatca gccatgtaga tgagcggata cgcctaatgt atggcgatgc
     8761 atatggctta acgatccaat cagtgattgg gacaggaacg actgtaacga tttgtctacc
     8821 gcttcttcct aaaaatcaat cagaatatca aaaataaaga atagccaagc gctgattttt
     8881 ttattttaag ttaaataaat caatcagtat tcttgacttt catctacgcg tctcttctac
     8941 tgtcagcact ggataacagc ccaatatttg actttctcct ccgagcatct tgatttcttg
     9001 gagcgcattc tctactaatg tcattggacg gtccaacaac aaatcgatca cgaaaaaata
     9061 ttctcccaag ctagttttca atggtcggga ttcaatctta cttaagttga tttcccgcca
     9121 gccaaaagct gccagcattt tatgaagcat ccctggccga ttagcaggta gtgtcaagat
     9181 gacactcatt tttactggag ctgactgctg gctggtcatc tttcggtcac cgacgatcca
     9241 aaaacgtgtc tggttcaact cattatcttg gatattctca gctaagatct ccaatccaac
     9301 atgctgtgct gtttctaatg aagcaatcgc tgctgcgtct tctttcggat gttctgctac
     9361 atacattgct gcagcagttg ttgattctgt tgctactaaa ggaacattag gataatgcgt
     9421 ttctaaaaac tgttgtgatt gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt
     9481 tgttgctgga ttgcctaaaa gctgctgctt gataggaaga acgatttcac ttttaacttc
     9541 gacttctgga tgtttggaaa gaagatcgat tgtgtgatga acagctcctt ccaatgaatt
     9601 ctctacagga acgacagcca gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg
     9661 gatggaagca tacgcagtca attgttctgt aggaaatagc tgacaagccg cctgataagt
     9721 gaatgaactt tctggcccta gatagctgac gttcatatgc ttttgatcct ttctataatg
     9781 gtatcgatga tcttttctgg tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct
     9841 tcataccaag aaagtcgttg tgccaataat gcttttattt cttctcttgt ttttccaaga
     9901 gctaaaggtc gaatagacgt ttcatcttgt tggatacgat caactagaca gtccgcttct
     9961 gcctctaagt aaagaacaat cggctgtgtt tttaaaaaac gccgattttc tgcactttgg
    10021 acaatccctc caccagtcgc gataattttg tcttcatttg acagctttct taaaatatct
    10081 gactccactt ttcgaaagct tttttcaccg taatagtgaa aatattcggc aatcgacaat
    10141 tggatatgtt cctcaatctt tgtatctaaa tctacatact ctttttgtaa acattgagct
    10201 aaccctttac cgattgttgt ttttccagcg cccatgaaac caatcagcaa aatgctagcc
    10261 atgagcttct cctcctgaca caagttctgc taaatcgtca aaaaatgccg gataagagat
    10321 tgaaacagct tcagctcctt ctagttcgca aggtccatca gctatcaaag cagctacttg
    10381 cagcatcata ccgattcgat gatcgcctct gctggacact tttgcgccat gcagaggtgt
    10441 cggcccatgg atgatcagac cgtctgctgt cgcttttatc tttgctccca ttttctgtaa
    10501 ttcttctgcc accgcatcaa ttctgttggt ttcttttact tttaattctt ctgcgtcttt
    10561 gatgatcgtg attccttctg cttgagtagc cactaaagct agaatgggca attcatcaat
    10621 cagacgcgga atgatttctc caccaatcgt tgctttcttc aaatgactcg tcttgacact
    10681 taaatcagcc gattggttct gttcattgtg attcgtctgg gtaatcgctg cgcccatctc
    10741 ctccaacaca tctaagatac cagttcttgt tggattgacc ccgacatttt ttaacaacag
    10801 ttggctttcc ggaacaagaa gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc
    10861 tggaacagtt atctgttgac cagttaattt ttgcggtccg gtcactatga tcgttttatc
    10921 ttccactgtg atccttccgc caaattgacg aatcatttct tccgtatggt tacgggaacg
    10981 ttctttttca acgattacgg atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga
    11041 tttgacttgc gcactggcta caggcatatt gtatcggata ggtgataaag agcgggttcc
    11101 tgtcacagtg attggtagat actggtcatt ttcttctcct tgcaagtcag cgcccatctc
    11161 gcgtaaaggt tccatcactc gccccattgg acgtttagac aacgaagcat ccccgaacag
    11221 agtagtcgta aaaggctgtc cagccaaaat acccatcaat aaacgtatgg tcgtaccgga
    11281 gtttcccatg tcaattgatt cggttggttg gacaaatgag tggctaccgc gaccatgaat
    11341 cttgatcacc tcttcctctt cttcgatctc gacacctaat tgttggaagg catgtaaagt
    11401 actcagacaa tcttctgcgc gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc
    11461 tccaaacatg atgctgcgat gggaaattga tttatctgct ggtatcctaa cagtccctct
    11521 taatccatgt atttgttgta ataattgcat ttatccagcc tcctatttga tccagcaatg
    11581 ataactggta ttagacataa tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa
    11641 actgatttgc agtattccta aaatatcttc cctggtctct tggatcttca aattaatcaa
    11701 agaaactccc gcttttccga tcagtccagt tacttctgca ataacgccag gttcatctgg
    11761 cacatcgata aataaatcaa aaaaggcagg aatcgcgcct tgcttatgga caggcaactg
    11821 gtctcgactt tcttttgccc gattgaaaaa agaaaagatt tccgattggt tctcagtcat
    11881 gatccattct gctatttgtg tcatttcttg ttgccaatct gccaatcgtt ccaataatat
    11941 ctgcttattg ctcaacaaaa tatctgtcca catgacagga tctgaggaag cgatcctagt
    12001 gatatctcga aagcctcctg ctgccagttg tttggctcgc ggatactctt gattgaattg
    12061 ttctgcctga ttgactaagc cagctgccag aatatgtgga aaatgactta gcattcctgt
    12121 tatacggtca tgttctcttg ctgtaagagt tacatatttt gctttggttc cgcaaaatag
    12181 ttcttgcagt ttttcaacat cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc
    12241 attttcaaat agtttagcat ctgctgcctg tatacctgat ttatgagaac cagccattgg
    12301 atgtccaccg acaaaccgaa gatttttctg ctcagcggat gtcacgactt gctgcttcgt
    12361 actgctgaca tccgtaatga tgacgtgatc agacaagttg attctttcaa ggacatcaag
    12421 ataagctaag gttgtacgga cgggaacggc taataagata acgtctgctt gttctgcacc
    12481 tgtttcaaaa tcacttgcaa cgtaatcaac gatctgctgt tctactgctt gctcacgggt
    12541 ttttgactga ctatcccaac caactactat cagttctgga ttggtctgac gaatacaaag
    12601 tgccatagaa gcaccaatca gtccaagccc cacgataaaa acatgttgtg ccatcttatt
    12661 tgcccccttt ttagtaatgt ttcaagtagt cacggtactc cttcactgca gctttcaact
    12721 caacaagcga atcacttggg aattttgaca atagctctgt cgctaccaca gtggctacaa
    12781 cattttccgc aacgacgcta gctgcaggaa ctgctgtact atccgaacgt tctacacttg
    12841 ctttgtaagg ttcttttgta tcgatatcaa cactttgaag tggcttgtac aatgtaggaa
    12901 tgggtttcat gaccccgcga atgacaagtg gttcgccatt ggtcattccg ccttcgaagc
    12961 cgcctagatt attggtacgt cggaaatagc ctctttcttc ttcccatagg atctcatcca
    13021 tcacttctga gcctggtaat gaaccagaag tgaatccgac cccaaattct acgcctttaa
    13081 aggcattgat actaaccaca gcttgtgcga ttttggcatc tagcttcgtg tcccattgta
    13141 cgtagcttcc taatccagct ggaacgcctc caacgagcac ttctacaatt cctccgatcg
    13201 tatctccatt tttctttgtc tgatcgatca aatcttttat tctttgctca actgctggat
    13261 caacaactcg tacttctgac gcttcagaaa tttctttgat ttcttgaatc gagatatttc
    13321 caggtatttc tgcttggatt ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa
    13381 gttcttccag aattttcttg gcaattgcgc cgattgctac acgcatggtc gtctctcttg
    13441 cagaggaccg ttcaagcaca ttccgaagat ctcgatgatg gtatttcata ccgcctacca
    13501 aatccgcgtg tcctggacgc ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca
    13561 cttctgctac agacatgaca gttgtccaat ttttccaatc tttattttct accactaaag
    13621 tgacaggtga accaattgtt ttgccgtgac ggatgccaga cgtgatccga acacgatctt
    13681 tttcgatctt catccttcct cctctgccgt aaccagcttg tctgcgagcg agttcgtgat
    13741 tgatttcttc ttctgacaga ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt
    13801 ctggtccatg ggattctccc gcagtcatat aacgcatctt acagtcctcc taagtaatct
    13861 ttgaatgtct ctgtgggaac aggaacgatt tttgcttgcc caatcttttc tagcaagatg
    13921 atattcaatt ggcttcctct tgctttctta tcatgggtta tcgcgtggaa taattcatct
    13981 ggatgactta gatcgtacgt aatcggcaga tggaattttt gaagtatcct ttctaaagca
    14041 gctgtcgatc cagttggaga caagccgatt ttttctgcat gagaagtgat ggctaccatt
    14101 ccaatagcta ctccttctcc atgactgact accccatatc ctgctgtatt ttcaattgca
    14161 tggccaattg tatgaccaaa atttaaaata agtcgatttc cttggtcaaa gacatcttct
    14221 tccactactt ttcgtttgat ttccaacgta gcagtaatga ttggaacagc atgttccaga
    14281 agatcttttt cgtctttcag ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct
    14341 gctgatttga tgatttcagc gattccttct cgtaaacgac gtaccggcaa agtttttaga
    14401 acctcaggat caatcaatac accagctggc tggctaaatg ttccgacaag gtttttcgct
    14461 ttgtttgtat tgactgctgt cttcccgcca atactagaat ctacttgtgc aagtagcgta
    14521 gtcggaattt gaacgaaatg gatcccacgc atgaacgtcg aggccacgaa tgctgctaga
    14581 tcacccacca ttcctccacc aagtgcaagt atcccatcgc tgcgggtaaa atcattatct
    14641 gctaaaaaat cgtataactc agctgcttgt tctaaagatt tactggtctc acccgccggt
    14701 acgattgaaa ggactggttc aaaattagct tgtctcaatt ggaacatgat tttttctgca
    14761 tatagtggag caacgtttgt atcagtgatc acagctactt tttgaggtct ccaaatcgtt
    14821 tgaagccatg atccagcctg ttctagtgcg cctttttcaa tatgaatatc gtatttttgg
    14881 ttatcaacat gtacagtaag cattcgtttc acttctttct tttaaaaagc tggaattaat
    14941 cgagtgtctg aatcttttcc attgcttctt tcatgatcgc aacttctttc atcatgcgtg
    15001 agtaagtctt ttcattcaac gattggggac cgtctgacca agcatttgca ggatcaggat
    15061 ggatctctac gatcatgcca tctgctccgc ttgccacacc cgcacgagcc attggtggta
    15121 caagttccca aattcctgta ccatgacttg gatcaacaat cacagggaaa tgagttaatt
    15181 ttttcatcaa tgggacagca cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc
    15241 gaatcccacg ttcgataaaa atgacaggag atttgtcttc gactgcaatg tattctgcag
    15301 cattaagcca ttcattgatc gtaccggaaa ttccacgttt caatccaaca ggtttacctg
    15361 ttttaccgac agcagatagc agtttaaaat tttgcatatt acgtgcgcca atctgtagga
    15421 tatcgctgta ctcagccacc atatcgatat gcccttcatc catcacttca gtaatcactt
    15481 tcattccaaa ttcatcagcc gcttgacgga tgtatttcaa tccttcttct tctaaacctt
    15541 ggaaagcata tggagaagta cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc
    15601 cggctttggc cattcgcgca cattctctga tttggtctaa tccttcgata gaacaaggac
    15661 cagccatcgt cacgaaactg ccgtcaccaa tttttactcc gtctacatcc acgactgtat
    15721 tgccaggatg gaattctcga gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt
    15781 ctactccttc atagcgtgta aatgctcctt cttgtaaact tcgcgtatca ccttttagtc
    15841 caatcactac tcgttctgtt ccttgatcga ttgagacttt gaatccttct ttttcgatat
    15901 gatcgacgac tttttttatt tgttcttccg ttgcttcttt tttcataatt actatcattg
    15961 tttttcccgc tttcttttgt ttacttatct atcttggctg attttctcta ctttttcaag
    16021 gtggttttac attaattcct actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt
    16081 ctttcctact tatgacccag ataatcaaca aaaaaagatg tccctgtagg aaattgcctc
    16141 tacagtgaac atcttcaacg agccttaaaa agcgctgcaa aaatataaaa tagccactat
    16201 agatgaattt ctctacgtgg ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac
    16261 aaacctggtt tgtttgtacc cacgaagtca tgaatacaaa cctatctaaa atagctaaag
    16321 taatacgtat tcagttttgt aagttttcta gatttcataa aaaatcgctc caaactgatg
    16381 taagaattgt acctagtata gacataaaaa aatcgactgt caatcatttt tatgaaactt
    16441 tttttaattt tctgatagtt aactttgttt ttcagaaaaa taacaattgg ttttattgaa
    16501 gaaaatagtc atgaacaaaa gtatctgaga acttttttac tctcttgttc atgacatata
    16561 gaataaagca gctttgtctt gtaaactccg tttttcaaat aataatctaa agattgctac
    16621 tgaataataa agccgatttc atggtcctct tcgctgctga ttcggtaagg tgactcaaca
    16681 tccgctcccc agctattgat acccccgact cctcttactt ttgcaaaaat cgtaagaacc
    16741 gttcgtcttt ctggcggtag ttcttctata tgtgttgcct gttccagttc ttctgctttg
    16801 aatggtaaag cggaaaaagc aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct
    16861 tcttgatctt tatccgtatt atccaacgtt tgatttcttg ttagttctac ccatttcgtt
    16921 tccatatgca tgccgcattc ttggggaaca aggtatgggg aaacggggag tcctgccact
    16981 ttataaatac cttcgacacc accagccatc cgatccggat atgtttcccc tgataggcct
    17041 tcatactcaa aaaattttgc tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat
    17101 tccggtaatc ctttttgtcc ataataatgc atattgacaa gcattttacc ctctccagcg
    17161 atttggtagg aaattgtcac ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg
    17221 atttcaaccg tttcagcgta ttcattactt gaatattgat tatttactgg agcaatcggc
    17281 aaatcgatct ttttattgtc caccagtact tctatttctt tgacttttgg atacaatccg
    17341 gctcctaacc acataccgga tttaaatcca aatccgctac ctctgtcatt atcggtcgtt
    17401 gctcgccaaa aaactggaag tgtttcccgg tatagccatt cttttccgtt tttattgagc
    17461 gattccagtc cgcctcttgt ataagaaaaa atataatgcg tattccccga tttgacacct
    17521 aatgtacagt cgccgaagac gattgcaact ttttccgtat ccatatgact tttatttact
    17581 gtatttttca taataatatc ttacctcctg catggcgggt ttttcttgtc catctgcaaa
    17641 aacgatccca ttccctgaga attcatagtc acttggttta tcgtcaaagt caccgccata
    17701 gcgcatcact tctctgcctg tgattggatc agtcacttgg atcgcctgat ctttaaaatc
    17761 ccatatatag cctccttggt acatttcata acgatcaagc aacgtcatgt aagaatccat
    17821 tccacctaac gaattcccca tgtcatgcat atattcacat aagatgaacg gtttttccgc
    17881 tttattttca aggtagtcaa tgatctcttc tggtggcgca tacatgcagc tttttacatc
    17941 tgaaatcgaa tcttcgaatg ctggatttgg aaaattccct tcataatgga caagtcgatc
    18001 ggggtctact tttttgaagt aatcgttcat ttgtcgaatg ttttcttccg cataagattc
    18061 atttccaaga gaccaaaaaa gaatacttgg atggtttttt aatgtttcga aattcgtttt
    18121 tgctcgatca agaacagccg cctgccactg aggtactgca cctggtacgt tgtaagaagg
    18181 ctcaaatgcg cccatttttt gccatgagcc atgggattcg aggttcgttt ccgccatcac
    18241 atggattcct gcttggtcgc ataaataata ccaagtgatc tggttggggt aatgagatgt
    18301 ccgtacgccg ttgatctttg cattttttat gatagccaaa tctttttcca tatcttctat
    18361 agtgatggcg cgtccttttt tcggatgcca ctcatgtcga tttaccccgt tgataatcat
    18421 ccgttttcca ttgaagtaga tgattttatc tttgatttcg attttacgaa aaccgaagga
    18481 atagtcaata tactccgtta ctcttttttc ttcgtctatc gtctccaatt caagcttata
    18541 taaattgggc tgaaaatgcc cccacagtgc cacattttca aatccatcga tgcgaatcgt
    18601 catttgctct tttaacggat attgctgttg atagatttcc ttcccatcag gatctagtat
    18661 cgctacattc agctgactgt ttttggctac ttgctcaaaa gacaaatcta cttcaagttt
    18721 gccattttga catttgtcat ctaagcgagg tttgatccaa agatcttcta aatggttttg
    18781 tcctcgagca actaagaaga catctctgaa gatcccaaaa aatcggaaaa agtcctgatc
    18841 ttccaagaat gcagctgtac ttcttttgta aacctccaca gctagaatat tttcttcttc
    18901 caaataaggt gttaaatcaa attcagacgg agtgaacgaa tcttcggcat acccgataaa
    18961 atgaccattc aaccaaataa acattgcttg ttctacacca gcaaaatgaa tcgagatttg
    19021 ttttcccttt agaccttctt ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc
    19081 tttagcagct gaaaagatcc cttccgcctc tttctcaggg cttgtcgtga aagggggacg
    19141 gcgaaataca tgtccctccc acggatacat cgtattgatg taatggatct tgtcataatt
    19201 tgctaattca atatgactag gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt
    19261 tttataaaat gtttttggtc gtaccgaagg atttggcgaa taacaaaaac gccatgatcc
    19321 atttaaagac tgtttaaggg aggatgtggt ttctacttct tcccttgttg cataacaaac
    19381 atgatcgcta tgtgcatttg attggttcac tctaaaaact tgtggatcat ctaaccattt
    19441 tatatttgct ttcatacttt tttccttctc tctcataact ttttgaaatg aagcagttct
    19501 gtttggaaat caccttgaaa atcggggaag taaagtccaa ctgtcatcaa ttcggccccc
    19561 gaaaatatcc gcttcgaggt ctgttcctga taaagtgcct catcatctaa ccccatcaga
    19621 tatacttcat ggaacgctgg ttgagctgaa gctagtatcc tccctaaaaa cacaatagct
    19681 tcatcttgtt taggagacac aaacatccat gcggcaatat tttcttcaaa aggactcgcc
    19741 aaacgataat aatggccata ctggatcacc ggacgaatcg tttgatagga tataatttgg
    19801 tcttttactt gctttttttc ttcaggagac agctttgtca aatccagttc ataaccaaaa
    19861 acagcgctca tagctgtttc tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga
    19921 tttggtacag ctgatacatg agctgtgatg gacgaaatcg gataagcaag gcttgttcca
    19981 tattggattt tcatacgctc cactgcatcc gtgttatcac ttgtccatga ctgcggcata
    20041 taataaataa acccggcatc aaaccgtcca cctccaccag aacagccttc ccataagatt
    20101 tccggataat cagttgtcaa atgttcaagt agttcataaa gcccgagcat ataacgatgc
    20161 gctacttctc cttgtctctg tgggtcaagg gtaatcgaat agacatctga aagcgaacgg
    20221 ttcatatccc atttgatgta gtcaagagga atcgtatcta aaatctttct catttgtttc
    20281 tcaatcgtct gccgaacatc taaccttgta aaatccagta catgttgtga tctggaagca
    20341 gaaggcattc tacctggctc ctgcataaga aaatcaggat gtgttcgata cagttcagaa
    20401 tcaaccgaga tcatttcagg ttcaaaccat aaaccaaatt tcaatccttt gctatgagca
    20461 taatctgcta tttcacgtaa tccatttgtc aacttgcctt catactcgaa ccagtctcct
    20521 aatgaagaat tgtccgcatc tctttttcca aaccagccat catctaatac gaacatttcg
    20581 atgcctagct cctttgcttc atcaatgatc gccttgattt tttcactatt gaagtcaaag
    20641 taagtggctt cccagttatt gaccagaatc ggccgttcag caaattgatg acgacctctt
    20701 gcgattcttt cacgtagcaa ctcatggtgg atctgactca ttttgttcaa tccctgactt
    20761 gagtaagaaa ggatcatttc aggtgtttga aaagactggc ctgcattcaa ttcccacgaa
    20821 aaacgatggc tgttgatccc accgacgact ctcaattgat tgatctgatc tttttcaagt
    20881 tcgaaagaat ggttgccgga ataaacaaat tgaagtccga tcgcttctcc agtattttct
    20941 gtcgtatgat gatgaactaa agcaataaag ttattcatat ggtgactgct cgttcctcga
    21001 cggctttcaa atacttttgt tccagataaa acagattgcc gtgaaatctg tctttcattg
    21061 acatgtgctc ctggcaaagc aatgacttca tcaaatcgcc tagtatgggc aaagtctagc
    21121 tggaaactag ccgctttttc tagtttgatt gtttctccgg tttcatttct tatctttaca
    21181 gatcgtgtga tcactgctct atcagtaaat atggtataga acaaatcgaa ataaatcgct
    21241 gtttctctat ccttaagtga aatcaccaac gtttgtgcct ctgacttgtc catcacataa
    21301 gtttgaggca agccttcgat ctctggcttc ccatctgtaa tataatggct gtcatatctc
    21361 agatccagta agtctgatcc attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc
    21421 atgctgccat gagaagagta ttcttgcggt agtgtatctt tcgacagaga ccggtcagga
    21481 tttaagggaa catttcctga aaatccacga tctcttcggg gataattttt attgtctttg
    21541 tactgcttga ctggtttgcc aaaataaata tgcgccaata cattgctttc ttctatcttt
    21601 atcagataag aaagaaatgt atttcgtaaa tggaagactc ggctcttttc atcaaataag
    21661 atgaaatttt tatctgtttt tctatgcgta atatccatca tttcactccc aacaaaacgg
    21721 aaaccgttta ctttttttta taattcctgt atactgttta ctaaacaatt ttgtcaataa
    21781 aaatttttta tttttttgag gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa
    21841 aggcaaatgt ctctcctgct acagtttccc gtgtgttgaa taacgatcag acgatccatg
    21901 tggctcagac tactcggcaa cggatagtag aggcagctgc tgcgttggat tatgacatca
    21961 gtactcgtaa atatatcaaa aagagaatgc cttcgattgg tgtgatctct acgatcggca
    22021 aagcgagcga agaacaggat atctattaca aacatttgcg agtagggatg gaagaagaag
    22081 ctcgacgtct gcatttaggg atgaatcgaa tctataatct atctgataat cctaaacaat
    22141 gggaagatct agatcagtta ggtgcggtga tcgttgttgg gactgttacg aaagaatcga
    22201 ttaccgcctt gttaaaacaa aacatgcaaa tagtcgtcgt ggataaccct gacatccagc
    22261 aagaggtcga tatggtgtat gcagatcttg aacggatgac taaaaccgta ctggaattgt
    22321 tcttagaaaa tggtcataaa agaatagcct atatcggggg atataaagtc gatatggatg
    22381 aattcggtgg gaagcagatt tctataaatg aaaagaggat gcgtgcctat cagcatttta
    22441 tgatcgatca tcacttagaa aaatatatgt cttatcatct aggtggctgg acagaaaaac
    22501 aaggtgaggt acttgcgact aatctattag aaaatgaatc ccctcttcct actgccattc
    22561 ttgtcgggag cgatccaatg gcaattggtg tctatcgggc attgaaacaa aaaaatatcc
    22621 aaattggaga agagattgtt gtagcaagct ttgataatat cgagacaatc gcaaacctct
    22681 cccctggctt gaccagtgtt caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa
    22741 tggcattgga gcgaattgac ggtatacggg acgaaccaat cattttgact tatcctgcac
    22801 gattgattgt tagggaaagt tttatcccaa gaacaaaaag gtattgaaag agaggttgtg
    22861 aaaagccgct tcgtttcttc atactcaaaa cgaaacggct ttttcacaac ctcttactta
    22921 tacttattca caaaatccaa tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa
    22981 tcaaattggt attcatgggt aatctctttt tttgtatctg tataaaacaa ggattgcacg
    23041 ggtaccttta attctgtcaa ccgattttct aatgcttgac cttgctcctg gaatgagtat
    23101 gcatttccgt cagttatata cgttggcgga aattccttag aaacatggtc agccacacta
    23161 gcttctttca attgctcact cgttttccaa tcttttgttc caatcaacga ccacgcaacg
    23221 gttttgacga aaaacttcat aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa
    23281 tcaacaggtc cccaataaga aatggttcct ttcagactat cttttggaag tagctgtttg
    23341 attttcattt gtttagcata cgcatcattc gtttgtatag ctgcatattg caatgcgatt
    23401 tgtgaacctg cactatctcc accaaaaaat aattgttcca tgtctagcaa tttgtcgtct
    23461 ttttcttcag ctaataaatc tttgatcagt tcattcactt gaagaacttg attagggtat
    23521 tctgaatcag gcgctaattc ataattcatc gcaaccactg cgatgttggc gtctgaaact
    23581 aattttgtcg caaattcttt gacacccgat ttatctccgc cgacgaatcc tccaccatgt
    23641 acccaaaata gaacaggaac aggccccttg ctgttttttg gatagtagat gtcataagta
    23701 ttctctttat acttggactc atacgtcaaa tctgtttttt tcgccacgtt tttttctgct
    23761 tgatcgaacg tttttttatc agtgatttga acagtatttg aaaacatatg gttgatcaag
    23821 aatgctccag gtctggggga aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga
    23881 atgattccga agaaccatcc gataaattta agaattttct ttttcataag gctccctcag
    23941 tagttagtat taagcattct gattatacca tagtgttatt tcctatcaag ctctcctaga
    24001 tgatttaatg attttcccca aacttcttct gcaatgcttt tgacaaaaga aattttttcc
    24061 attgttcttc aaacaaaaca ttttcttctt ctgttgaagc aaatccacat tgaggactta
    24121 agcacaaacg atccaaaggc agatatcgtg tcgcttcgta gatccggtca atcacttgct
    24181 ggtgctcttc catttcgcca tttttcgtta cagtcaaaat ctaagacaac taatttatct
    24241 tcagagactt tctctaaaag aacaaaagtc ccagcacgtt cactatcgta ttctaaataa
    24301 taggcacgga cattttcttg agtaaaataa tgggtctgct acgtcgtcat cccccctgat
    24361 gccgccaaaa tcgaataata atttccgcgt caaacatgta tatttagtgt tgaatcattt
    24421 gagaatatga aaataaaaat ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa
    24481 atctgagaca gaatgacgtt cattctgacc cagatttgat tttgcacaac tcaacagtcc
    24541 ttattggcaa atcgccaaaa taatgtagac taactaaaa
//
LOCUS       DAPBBV010000044        23905 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.044, whole genome shotgun sequence.
ACCESSION   DAPBBV010000044 DAPBBV010000000
VERSION     DAPBBV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.044"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(186..311)
                     /locus_tag="RD486_002143"
     CDS             complement(186..311)
                     /locus_tag="RD486_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7663864.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(445..1338)
                     /locus_tag="RD486_002144"
     CDS             complement(445..1338)
                     /locus_tag="RD486_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HDT7663865.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(1520..2446)
                     /locus_tag="RD486_002145"
     CDS             complement(1520..2446)
                     /locus_tag="RD486_002145"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HDT7663866.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(2531..3292)
                     /gene="pflA"
                     /locus_tag="RD486_002146"
     CDS             complement(2531..3292)
                     /gene="pflA"
                     /locus_tag="RD486_002146"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDT7663867.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(3536..5767)
                     /gene="pflB"
                     /locus_tag="RD486_002147"
     CDS             complement(3536..5767)
                     /gene="pflB"
                     /locus_tag="RD486_002147"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDT7663868.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6044..8494)
                     /gene="parC"
                     /locus_tag="RD486_002148"
     CDS             complement(6044..8494)
                     /gene="parC"
                     /locus_tag="RD486_002148"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDT7663869.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(8506..10551)
                     /gene="parE"
                     /locus_tag="RD486_002149"
     CDS             complement(8506..10551)
                     /gene="parE"
                     /locus_tag="RD486_002149"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDT7663870.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(10717..11151)
                     /locus_tag="RD486_002150"
     CDS             complement(10717..11151)
                     /locus_tag="RD486_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDT7663871.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11278..11916
                     /gene="plsY"
                     /locus_tag="RD486_002151"
     CDS             11278..11916
                     /gene="plsY"
                     /locus_tag="RD486_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDT7663872.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12048..12923)
                     /locus_tag="RD486_002152"
     CDS             complement(12048..12923)
                     /locus_tag="RD486_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDT7663873.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13005..13796)
                     /gene="codY"
                     /locus_tag="RD486_002153"
     CDS             complement(13005..13796)
                     /gene="codY"
                     /locus_tag="RD486_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDT7663874.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(13814..15214)
                     /gene="hslU"
                     /locus_tag="RD486_002154"
     CDS             complement(13814..15214)
                     /gene="hslU"
                     /locus_tag="RD486_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HDT7663875.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15228..15776)
                     /gene="hslV"
                     /locus_tag="RD486_002155"
     CDS             complement(15228..15776)
                     /gene="hslV"
                     /locus_tag="RD486_002155"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HDT7663876.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(15813..16718)
                     /gene="xerC"
                     /locus_tag="RD486_002156"
     CDS             complement(15813..16718)
                     /gene="xerC"
                     /locus_tag="RD486_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDT7663877.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(16916..18292)
                     /gene="trmFO"
                     /locus_tag="RD486_002157"
     CDS             complement(16916..18292)
                     /gene="trmFO"
                     /locus_tag="RD486_002157"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HDT7663878.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18261..20339)
                     /gene="topA"
                     /locus_tag="RD486_002158"
     CDS             complement(18261..20339)
                     /gene="topA"
                     /locus_tag="RD486_002158"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDT7663879.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHGHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(20461..21318)
                     /gene="dprA"
                     /locus_tag="RD486_002159"
     CDS             complement(20461..21318)
                     /gene="dprA"
                     /locus_tag="RD486_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDT7663880.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21374..22141)
                     /locus_tag="RD486_002160"
     CDS             complement(21374..22141)
                     /locus_tag="RD486_002160"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDT7663881.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22134..22994)
                     /gene="ylqF"
                     /locus_tag="RD486_002161"
     CDS             complement(22134..22994)
                     /gene="ylqF"
                     /locus_tag="RD486_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDT7663882.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            complement(23088..>23905)
                     /locus_tag="RD486_002162"
     CDS             complement(23088..>23905)
                     /locus_tag="RD486_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7663883.1"
                     /translation="KSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDV
                     IVGRAAFPIRCSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHERE
                     KDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHW
                     FESVPKNLFKSITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRD
                     GLLKSMDFNSVDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         6280 a         5155 c         4120 g         8350 t
ORIGIN      
        1 atttatgtgg caaagaaaaa acaaacaaaa taaaaagcat tttgaagcct gactattacg
       61 acttcataaa tgctttttta gttttaaaca cttcaatcta aaagaataac ccaagattgg
      121 ataaattatt aatgactcgc cattcgtttc ttagtgattc tggattatca aatggacttc
      181 ctaatctaat cagctagttc ttcccataaa atgccatact tgactgaatc ataatattga
      241 ttatttaaaa atctaacttt tcttatcact acttcctttg tcattccaca tttctcacca
      301 tttttttgca ttcctttgtt tccagaccat gtagtgaatc taataggtgg tagataggca
      361 aaatactcaa ataattcttt taaccataaa ggaagagaaa ggctcctcct gcaagagtca
      421 gtataatttt tgcttactgc tctcttaggt tttactcact aaaactgttc catattcttt
      481 gatataagaa aatgcatgcg gtataaattt cttgctcagc tcagaaaaga tttgtcgttt
      541 aagaaaggcc atttcctcca ttgtcaatga aggatccaat gttggtaatt caatctcaaa
      601 attgtttttt tcgacaatag gtaattctaa tgtgaatgat tcttcttcct ttatagtatt
      661 cgtcacaagt agagactgat ggaaaatact aggccggcga tttttatatt tattcttacg
      721 tatcctgtca acgataactt ctatttgatc aaaaaagtac gattcattta cgtctccaat
      781 aagttcggct aattctttga atgccttcgt tacaggaagc tgattcttct gtacaaaaaa
      841 gtaattagcc aaagtaagcg ggaagtgttc tatagaggaa agtgtgataa aacggtactt
      901 ctcatttcct gcagttgtcc tcagcaattc tgtctctcgg ctgtttctta ctccataaaa
      961 atacgcttct ttccgttcat cttcgaaaca atacgcccaa ataacttctc ccatcgctaa
     1021 tttttgttca tcaacagaga gtctcttcaa ttgttcagct atggtttcag cagccgaagt
     1081 ggcttgttgc aagtaatctt taggatcaaa tattggaaag ttcaaatgat atcttcgttc
     1141 ttccctcttg attaatcctg catcgatcaa taaatcaaga aaatgggaaa atttattttg
     1201 cgaaaattct tttttcaatt ctcttagaat cgtttcttgt tctcgatgtt catatagata
     1261 atcggtcaat gaagaaaaaa gcggatcatc ggtcagtttt tgataaaagt tttccttatt
     1321 ttttgaataa tagttcatat atgttctctt ttctatccgt tttattttac ttaaaaggct
     1381 tttacgtaaa aaggaggaag aacaagagtc ataattgact gttattctcc tccatttctt
     1441 cggcctttag tatgttctat gtttcttttt atatcaatcg cttatccatt cattttgaat
     1501 gcttcatact accatttgat tagctaaata cagccgtcaa ttgaggtacg acttgttttt
     1561 tacgtgaaac gacaccttta agcaaagcac ggttgttggt caaagttgtt tggaaagctt
     1621 cttctacttt ttcttttcct ttaccagcaa caagtaattc tgaatcactg tctaagatgt
     1681 ttgtgacaac taatacgaac agatcgtagc catttgcttt catttcatct tccattgctg
     1741 cttctagctc tgcttgtcga tccatcactt cattaaggtc cactgtattg acttgagcga
     1801 tacgaacgtt ggaactgccc attgggaaac tttttgcatc caaatcaaga agaaccgcag
     1861 ctgatttatc acttagattt gttcctgctt tcaacatttc aagtccataa gtgtttagat
     1921 cgacttcagc gattgctgca agttcttttg cagctgcttc atcttcaggc gtacatgttg
     1981 gtgatttgaa caacaatgta tctgaaatga tagctgagag catgattcct gcgatttctt
     2041 taggaattgt tacttggttt tctttatata gttttaaaat aatcgtactt gtacatccaa
     2101 ctggttctgc acgatagtac aatggattag ctgtttcaaa gtttgcaata cgatggtggt
     2161 ctactacagc taaaatattt acttcgctga tatctgaaat actttgttgg aattcattat
     2221 gatccacaag catgacatct gcattttctg ctttagctga ctctactact cgtggtgcag
     2281 atagctgaaa gtggtctaat gcgtattgtg tttcttcatt aggtgtacct agagcaactg
     2341 cttctgtttc tttacctaat tcattttgca agtgtgaaaa cgcaatggct gccccgattg
     2401 catctgtatc tggattttgg tgaccaaaaa ctaaaatttt tgacatgtca ttcgctcctt
     2461 tgtgatttct cctatttaat aatagcaaaa aaacggaaag aagcaatact tatcttcttt
     2521 ccgatgcgac ctatcgcgtt aaatattttg tatactcttc tgtatgaagc aatcgtttag
     2581 cattttcgac acgttctttt gtaggtggtt cgatcccttc taatggatat ttcaaaccaa
     2641 gtgtttccca cttgtatttt cccatcgtat gataaggaag aatctctact ctgtctacat
     2701 ttgacaaggt ttgaataaag ttgtctagtc ggatcaaata ttcatcataa tcacttcgct
     2761 caggaactag tacatggcga atccaaaccg gtttgttgat ttttgacaaa tattgagcca
     2821 tttctaaaat attttcattg tcccaatgcg ttagtttttt atgctcttca ttatcgatgt
     2881 gtttgatgtc aaataacagt aaatctgtat acttcatcaa ttcttgaaaa cgtgaaaaga
     2941 aaggttcttc atacgtaaaa ggttttccgc atgtatccaa tgtagtatgc atcttccgct
     3001 cttttgcttt tttaaatagt tcgatcaaaa aatcgatctg caatagaggt tctccaccac
     3061 taacagtaat accaccttta tctccccagt aaggtctgaa gcgttctgct ttatctaaaa
     3121 gttcatctgc tgtgtattct ttccctccgc caatattcca agtatctgga ttgtgacaaa
     3181 attggcaacg catgcggcat ccttgcataa acacgacaaa gcgcagtcca ggtccgtcta
     3241 ctgaaccgaa agtttcgata gaatgaacat agccgattgt tttttcttcc atttaagttc
     3301 acatcttttc tttgatttca ttttaagtac aagttagctg tcgaagcgaa gctttctgaa
     3361 caaaattttt cgcaattgcc gcttcgttat gtgtaaaatt tacagggacg gaacatacaa
     3421 gtcctgcccc tgtaaatcgt ttctttcaaa taagcatact gattattcga ttttgatgcg
     3481 atggctattc aacgtccttt cgacgctaag tcgaaaaact tttttcacga actttttaca
     3541 ttctgtcgtg tgaagttctc atcaagacat ctaattgttg ttctcttgtc aagtcacgga
     3601 atttaactgc ataaccagat acccggatcg tcaagttcgg atatttcatt ggattttcca
     3661 ttgcatcacg caataaatca ttactgaata cattgacatt caaatgataa gctccttttg
     3721 agaagtatcc atctaagaca ttacgcaagt tttcgattct tgtatcttgt tcttttccaa
     3781 gacctgaagg attgattgtt tgggtatttg aaattccatc caatgcacag ccgtaattca
     3841 ttttagctgt tgagttcagg ctagctaata acccactttg ttccgcattg taacttggat
     3901 ttgctcctgg cgcaagtggt tttccagctt cacggccatc aggagtattt cctgtatttt
     3961 taccgtaaac aacatttgaa gtaatcgtca ataatgaagt tgttggtttt gagttgcggt
     4021 aagttttatg acgtttgatt tgtcccatga agtattccaa gatccatgaa actaattcat
     4081 ctgcacggtc atcatcattt ccgtatttag ggaagtcgcc atccacttca aaatcaactg
     4141 ctattccttt ttcattacgg attgctttta cttttgcata tttgatcgct gacaagctgt
     4201 ctgccgcatg agagatccca gcaatacctg tagcaaatgt gcgttgcaag tcagaatcca
     4261 tcaaagccag ctgagctgct tcataagaat atttatcatg catataatga atgatgttca
     4321 acgtattgac atatagttct gctaaccaat ccatcatatt catgaagtta tgtttcactt
     4381 cttcaaagtc tagtatttct gatgtgattg gacgatattc tggtccaact tgggcgccag
     4441 tcacttcatc gactccgcca ttgatggcat ataatagtgt tttagccaag ttagcacgag
     4501 cgccaaagaa ttgcatgtct tttccgacaa ctgttcctga tacacagcaa gcaatcgcac
     4561 aatcatcaga accccattgt tcacgaagct gattatcatt ttcgaattga atcgaagaac
     4621 tttcgatagc gattctgcta gcatatgttc tgaatccttc tggaaggtgt tcagaataca
     4681 aaacagtcaa gtttggttct ggtgaaggtc ccatatttgt taatgtatga agcagacgga
     4741 aatcattctt tgtaactaat gaacgaccat ctaatcccat acctgcaatg gataaagtag
     4801 cccagatagg gaatcctgag aataattggt tatattcagg tgtacgcgcg aatttgacca
     4861 tacgtaattt cattactaag tggtcgatca attcttgtgc ttctttttct gtgattactc
     4921 cattatccaa atcacgttgg atatagatat caaggaatgc tgagatacgt ccgattgaca
     4981 tcgcagcacc attttgtgat ttgattgctg ctaaatatcc gaagtatagc cattggacag
     5041 cttcttttgc atttgcagct ggtttagaaa tatcatagcc atatttcgca gccatttctt
     5101 tcatttgcgc taatgcacga tattgttcag tgatttcttc acgtaaacga atcacttctt
     5161 cactcattgt atgataacca gtcatatcat gatctttttt cttttgttcc atcaaatagt
     5221 cgattccata caatgccaca cgacgatagt caccgatgat acgtccgcga ccgtaagcgt
     5281 ctggaagccc tgtaatgatt ttgtttttac gagcagcacg catttcagca gtataagcgt
     5341 caaatacacc ttgattatgt gttttgcgcc agtcagtgaa aatatgtgtc aattcatcgt
     5401 ttggtgtata gccattgctt tttagcgcat tgttagccat attgattccg ccgaacggca
     5461 tgaatgcttg tttcaaaggt ttgtctgtct gtagaccgac gattttttcc aaatctttat
     5521 ccaaatagcc tgcatcgtgt gaagtaatag ttgatacgat ttctgtgtcc atatcataga
     5581 caccgttacg ctcgaattgg atatcattta acttttgcaa ttcatcccat aatttttctg
     5641 ttgcttctgt tgggccttcc aaaaagctgt catcaccgcg atattcagtg tagttatttt
     5701 gaataaagtc tctagtgtct acgccttctt tccatttggt acctttaaat ccattccatt
     5761 gctccattgt atggacctcc taaatttctg ttttatgtaa cagtttttac gtgattagta
     5821 taacacagca ccctatcttt gcaagggttt tcttgttttt tatttaacaa tttttatgtt
     5881 ttatttacat atatttaaat caacgttgac ataccaacat ttaagcattg tgaacacttt
     5941 catctttttt tgcaaacgta taaggattta ttaaaaatga atgaaaaaga gacgccacct
     6001 gtattaatac agatggcgtc tcttcattaa aatactacaa cagttacgac tcgatgaaaa
     6061 tctcaggagc atcgataact tcgatgactt ctccaccttt tttctcatcc atcgcaaatg
     6121 atccattcga tgttcgatca cctataggga aatcagttgg gtcaatcgtt aactgctgcc
     6181 ctttttgatt catcaaggtt atttcttttg atcttccttc cgacatatag ataatacggt
     6241 gcggattttt tttcagctca cgcatgaccg tcactccccg cttcgcacgt gaagtttggc
     6301 tgatttcttg agcaagcatg cgtttaacag ctcctcgctg agtaacgatt acgatcggcg
     6361 tatcaccttc tgctaacaca agcagcccgt tgataatcct atctccatct ttcaaattca
     6421 tagacttcac tccagctgcc tttgctccaa caacgggaac atctgttaaa ggatagcgca
     6481 aacccattcc ttgatgcgtt actaagaaaa catctaagcc tggctgatct tctttcagat
     6541 acacagcaat cagttcatct tcttccgcct ttagcttcat acagctgagc ggacggctct
     6601 tataggtgcg ccatggttcg aactctgtca ttcgtgtttg cttgatcaat ccattcttgc
     6661 tgatgaatac aaatgttttc tctgcttgaa ttttttgata tgggaaaaca gctaaaatcg
     6721 attcgtctac agacagattg gagattgttt gagaaatgtg ctcaccagca tctttccatt
     6781 tcaaatcggg tagttcatgg acagggcggt agatcacatt tgctttattt gtgatcagaa
     6841 gaacatggtc caatgtactc aattcacctg agtatagcaa gtagtcgcct tctcgcatcc
     6901 cgatttcttc tggtttggaa gcactataag aacgaaggct tgttcgcttc acatagcctt
     6961 ctcgcgtcac actgacaatt acgtcttctt gtgccactaa gacttgcgta tcaattttga
     7021 tttcttcgat ttcgtcttcg attgtcgtta gacgagcgga agaataattt tttttcactt
     7081 ctcgcaattc ttttttcata acagagaaaa gctctttgtc atttgaaagg attttattca
     7141 actctgtgat ttgcgcaatc aagctttcgg attccttttg aagctctgtg atatccgtgt
     7201 tcgtcaaacg gtataattgc aatgtgacaa ttgcttctgc ttgttcttct gtaaattgaa
     7261 agacgtcgac taaattcttt ttggcgtctt ttttgtcttt actttcacga atcgttgcga
     7321 ttacttcatc cagaatcgat aaagctttca tcaatccttc tacgatatgc tgtctttttt
     7381 gagctttggc taaatcgaat tgactacgtt ttgttatgac ttgctttcga tgctcgatat
     7441 aacttcttaa aatgtctttc agtccaactt gatgcggagt catatggtcg atagcgacca
     7501 tattgaaatt gtaattgatc tgtagctcag tgtttttgaa caaataattc aaaattcctt
     7561 gagcattggc gtcttttttc aattcgacga caatttgcag acctgttcta tcactttcat
     7621 ctcgtacttc agctattcca tcgattttct tattcaaacg gatctcatcc atttttttca
     7681 ccaaggtcgc tttatttact tcatatggga tttctgtgat cacgatttgc tgtttattac
     7741 ccttcattgc ctctatcttt gttttcgaac gaagaataac ttttcctcgt cctgtttcat
     7801 aagctttttt gatttcatct tttccttgca agatccctcc tgttggaaag tcaggtccag
     7861 gaatatattc catcaatttt tcaaggctcg cttgtggatg atcgatcata tagattgtgc
     7921 catcgatcac ttcagctaag ttatgagtcg ggatttctgt tgcatatcca gcagatatac
     7981 ctgtcgatcc attgacgaga aggtttgggt atcgagctgg aaggactgtt ggttcttttt
     8041 ctgtatcatc aaaattccac acgagatcga ctgtttcttt ctcgatatct gctagcatct
     8101 ctccacttaa cttggataat ctggcttcag tataacgcat cgcagcaggt ggatcaccgt
     8161 ccatactccc gttattcccg tgcatttcga tcagtacttc ccgcaacttc cagtcttggc
     8221 tcatgcggac catcgcttca taaatactga tgtcaccatg aggatgataa ttccccatga
     8281 tatttccgac agattttgct gatttacgga atcctttgtc atacgtattg ccatctttgt
     8341 tcatggcaaa taatatccgg cgttgcactg gcttcaatcc atcacggata tcaggcagtg
     8401 cacgttcttg gataatatat ttggaataac gtccgaagcg gtcacccatc acttcttcta
     8461 aagttaattc ttgtacttct tgtcgatttt ccatcaggtg acctcctatt ctacttcaaa
     8521 taactgattg ttttcatttt tatctgctcg ttcttcatct aataaatcat tagaaactga
     8581 aggagagatt tcagtatcct cttttttatc taagatactg ccatcttctt cgagcgtaaa
     8641 ttgcacgtga ttttcgatcc attttcttcg aggttctact ttgtcaccca tcagtgtggt
     8701 tactcgacgt tcagcttgcg cagcatcatc gatacggacg cggatcaacg tacgggaagt
     8761 cggatccatc gttgtttccc acaattgttc cgcattcatc tctccaagtc ctttatatcg
     8821 ctgcagcata tatcctttgc cgactttttt aatcattgct gccaattcgt catctgtcca
     8881 cgcatattca atgacttgct tctttccttg tcctttggat actttatata aaggcggtaa
     8941 cgcgatatat actttcccag cttcaatcag cggtttcata taacgataaa agaaagtaag
     9001 cagtaatact tgaatatggg cgccgtctgt atccgcatcg gtcatgatga ttactttgtc
     9061 gtaattacag tcttcgatag aaaactcagg accgactcct gcaccaatcg tatagatcat
     9121 cgtattgatt tcttcatttt tcaagatatc ttgcatttta gctttttcgg tattgatgac
     9181 ttttcctcgt aaaggtagaa ttgcttggaa ctttctgtct cttccttgtt tagcagatcc
     9241 gccagcagaa tccccttcga ctaaatacaa ttcatttttc ttagggtttc gggattgtgc
     9301 gggtgtcaat tttcctgaaa gaagagattc gcctttttta cgcttcttcc catttcggct
     9361 ttcttctctg gctttacgtg ctgcttctct cgcttctctg gctttgattg ctttacggac
     9421 caacatctgg ctcatttcgc tattttcctg caaataaaag cccatttgtt cactgatgac
     9481 gttatctact acggtacgag caactggcgt accaagtttt tcttttgttt gcccttcaaa
     9541 ttgcagaaga ttttcaggta cacggataga aagtacagca gctaaccctt ctctgaaatc
     9601 actaccttcc agattcttgt cccgttcttt cagcaaacca acttttctcg catattcatt
     9661 ataagatttc gtcatcgccg ctttcatacc agcttcatgg gttcccccat cttttgtccg
     9721 aacgttattg acaaaagata aaacattttc tgaataaccg tcattgtatt gataagcgac
     9781 ctctacttcg ataccttctt tttctcctga aaaataaaca actggtgtca atgtatcttt
     9841 ttcttcattc agataatcaa caaattcttt gattccttct tcgtaatgaa aaatttcctt
     9901 gactggttct tctccacgaa gatcagaaag agagatttta acgcctttta gaagaaaggc
     9961 agattctctt aaccgttcgg ctaaaatttc atatgaaaat ttcgttgtac tgaatattgt
    10021 atcatctggt aaaaaatgga cagtcgtccc gtttgctttt tttgtttttc ctatcttttt
    10081 caaagtaccg tcaggtttac cgccgttttt aaatttctgc tgatactcta cgccatctct
    10141 aacgatcgtt acaattagcc atttcgataa ggcatttacc acactggctc ctacaccgtg
    10201 cagtccacca gaagttttgt accctccttg accaaacttt ccgccagcat gcagcacagt
    10261 aaaaatcact tcaactgttg gtattccgga agcatgcatt cctacaggca tcccacgtcc
    10321 gctatctgca acagttatac tattgtcttc atggatggtc acatcaatct cactgccata
    10381 acctgataat gcttcgtcaa ctgcattatc gacgatttca tagactaaat gatgcaagcc
    10441 tcggctgtca gtggatccaa tgtacatccc tggtcttttt ctaactgcct ctaatccttc
    10501 caatacttgg atggacgagt cattgtattc gttgtttact ttttttgcca aggcaaacgc
    10561 tccttcaata atactttgcg gcaaaaccgc accacgatta tcatactaga aaaggtcgtg
    10621 aaaaaaaaga gggtagacga gaaatcaatt ttaattatct cctaaccgct ttttcgacat
    10681 tcccctctat cgatcatctc ttctttgtgg tcatttttat ttttggtttt ctttcaactt
    10741 accaagttca atcttaatac aacgatccat tacgatatct gtacgtcctg cttttcttag
    10801 catctcagct gcttctttgt tttcaatccc taattgtgcc cagaacactt tagcatcagt
    10861 tttcaaaaaa tcacctgcta tttcaggtaa aaattcactc cgtctaaata catctacgat
    10921 atcgattgga tcatcgattt ctgtcaaatt cgcatagact ttctcgccta gaatttcttc
    10981 accagccaat aatggattta ctggtatgat tttatatcca ttgtcttgca atacctgtgc
    11041 aaccatgtaa cttgttcgtt ctggtttatt gctcaagcct acgacggcaa tattttttgc
    11101 ttcttccaaa tagttgaaaa tcgtttcttg tgttggattt tttacagaca tttctgccac
    11161 cccttgcttt tctttttatt ccatctatta tacttgtatc tttcattttt tcaattgttc
    11221 ctgttaccta ttcatgctaa aataaaggat agttttcaac ttgaaagagg gtaaaaaatg
    11281 aaattgatct tattacttat tttagcatat cttttaggtt ctattccttc cggtgtctgg
    11341 attggcaaat tgtttttcaa aaaagatatc cgacaacacg ggagcggtaa tactggaacg
    11401 accaatacat ttcgtgtatt aggcaaaaca gccgggattg ttgtcctgct tatggatatt
    11461 ttaaaaggta cattggctac ttgtttgccg atgatcttcc acctttctgg gattaaccct
    11521 ctttggtttg gggtatgcgc cattcttggc catacatttc cgatttttgc tgggttcaaa
    11581 ggaggaaaag ctgttgcgac aagtgcagga atgcttttag gatttaatcc tgtatttttt
    11641 gtttattctt gtatcatctt tatcgttagt ttattttgta caagtatggt gagtttgagc
    11701 agtatgatca gtgcagtatt gatcacttta tctacgatcg tccttcctta tgtagctcct
    11761 gtgattttgg ctaagcccaa ttggttactg acgatcattg cctttttagt ttcttccttt
    11821 atcttttatc ggcataaaga caatatcaag cgtatcagaa accatactga aagtcgaatc
    11881 ccgtttggtt tgaatagcag caagaaaaaa tcctgatact ttttcattcc aaagagataa
    11941 aacgggagtg tgacaaatcg atgtcacact cccttattac ttacaggata gcttttttac
    12001 acaccttggt aaacggtgtt ccctgctaac ttctcggtca caacctctta cttcactgtg
    12061 atggaatatt ttgtcttgaa gatttcatgg gcacctagtt gattgatccc tactttttcc
    12121 atcaagtttc cactactgtt caccgtgtca gcgattccgc accacggttc gatacaaacg
    12181 aaaggcgctt cttttggata aggagaccag atccctacat aaggcatatc tttatagctt
    12241 aaagttacgc tatgggaaga tttttcactt cgaatggcgt acgcatttag accccttgtt
    12301 tcaaaaacca aggcatcttg ctcaaaaagt tcacgattca aagccagatt cgtatttgtc
    12361 tgacctaacg tcttttgatc catatcgatg aatgggcctt tcaatggtag gcgtaatctt
    12421 gatttcaatg gagaaaatgc cagatagaaa tcttcaaatg acaatccttc ttcaagaggt
    12481 acattgaaag caggatgtcc accgatagaa aagaacattt ctttttcacc ggtatttgcc
    12541 acttgataat gaaccgtgat gccgtctcct cctaattcat agctgatcac taattcaaaa
    12601 tcaaatggat acttttctaa tgtctccggc gtactcctta agatgaaact agccatttct
    12661 tgtccatgtt caatgacttc aaaatccata tcccgagcaa atccgtgttg ccccatttga
    12721 tatgttttcc cttgataaac atactgatca tcttttaaac gtccaacaaa agggaataaa
    12781 accggtgcat gtctgcccca atacgctgga tcaccttgcc agatatactc taaaccatgt
    12841 tcttttgatt tcagactgat caattccgca ccgtgttcag cgatttcggc gatcagctgg
    12901 tcattttgaa taataacagt cattgccatt cctccaactt cgacttactt tttaaaatgg
    12961 gaaggctgga acaaacattt ctatctgccc cagtcccctt acttctaata actgtgtttt
    13021 gctaactcgt ctttaaaacg ggaattcaat acttttaaat aagttccctt catgcctaac
    13081 gaacgagatt caatgattcc agctgattcc aattttcgta aagcattgac gatcacagaa
    13141 cgagtgatgc cgatactatc ggcaatatta gaagcagtca gacgaccttc atctccatcc
    13201 aatgcttcaa agatagcttg tacagccttc aattcgctat aagataatgt gttgattgcc
    13261 atttggacag ccgttgcact ccgtacatct gcttcgatgc ttcgagactt ctgataaagg
    13321 atctgcatac cgacaaccgt agctccatat tctgctaaga ctagatcgtc atctgcaaac
    13381 gattgttcca tacgagataa gataatcgta cccaaacgtt cgccagctcc aaagatcgga
    13441 acgacagtcg tcagaccaaa tggatatttc tctcttgact ctaccggaaa tgcagtaata
    13501 tcactagtaa ttgggatatt agcttcagtt ttcatcaact gtgccactgt atcagtataa
    13561 gattcaggaa attgtttctc aacaaacatt gttttgattc gttcattgtt cacatcgtga
    13621 cgttcattat aacctagtaa tactccgtca cttcctatga tataggtgtt gctgtcaaga
    13681 ataccaccta gtgtgacagc cattttatcg taaggcaaat ctgcttgcat gtcaaaagta
    13741 ttcttttgct gcaaaagtgt gtttatcttg cgggttttcg ttagcaagtc tgtcattgtc
    13801 gtcctccgat tttttataaa atatagcgac ttaaatcttc atttgccgca attgagccaa
    13861 gtttgtcatc cacatatgct tctgtgatcg ttatttctcc catttgcata tctggtgctt
    13921 caaataatag atcttctagt agtttttcca aaatggtatg cagtctgcgt gcgccgatat
    13981 tatctgtgtc acggttgaca tcgaaagcga tttgagcgat ccgttcaatt gcttcttttg
    14041 taaacgtaac tgacacattt tctgtaccga tcaacgcgac gtattgtttt actaaagcat
    14101 tatttggttc ggtcagaatc ttcacaaaat cttcagctgt caaatcatct aattctaccc
    14161 gtatcgggaa gcgtccttga agttctggaa ttagatcact tggtttagac aaatggaaag
    14221 ctcctgaagc aatgaatagg acgtgatctg tttggatgat cccgtatttt gtgtttactt
    14281 gtgaaccttc gacaattggc aatatgtctc tttggacgcc ttctctggat acttctccag
    14341 attgctgtga tttagaagtg atcttatcga tttcatcgat aaaaataatt ccactttctt
    14401 ccgctaattt gattgcctca ctatggatat cagcatcctt gactaatttt gctgattctt
    14461 ccttgatcaa taactctaaa gcttctttga ctgttaccgt ccgttccact tttttcttcg
    14521 gtgtcaaagc acctagagtt tcatttaggt cgatccccat ttgctccaat ccattgttca
    14581 tcattggtgc aggtttcttt tggtcttcaa cttcaatggt tacttcacga ctatccagta
    14641 aacccttttg tagttgttcc aagactgtac ggcgattgat tcgaatatct tctgtcactt
    14701 cttcttgcgg ttcagcggta ttttgctgac tagcattaaa aagattcatc atttgttcaa
    14761 attgattagt ggattgtttc tgttcttttt tgataccagg taccaagatt tttaccaaac
    14821 gtttttctgc atttttttta gcacttgtgt atacacggct gtactgctct ttttctacga
    14881 tttggatcgc attttctact aaatcccgaa ccattgattc tacatctctt ccgacataac
    14941 cgacttcagt aaattttgtt gcttcgactt tgacaaatgg tgcattgacg atttttgcca
    15001 aacgtcgtgc gatttctgtt ttaccgaccc ctgtaggtcc gatcatcagc atattttttg
    15061 gtgtaatatc ttgttgcatt ttttcatcta actgcaaacg gcgatagcgg ttacgcaaag
    15121 caacggcaac agattttttt gctgcgtgct gtcctacgat atattcatct aattcactta
    15181 cgatttgtct tggtgtttgt tttaattcat acatatctac tcacctctta cagttcttct
    15241 acgataatat tatgattagt aaagatacag atatctgcgg caatatttaa cgcattttct
    15301 gcaatttctt tcgcactcat gtcgttttga gcatagtttt tcattgctcg ggctgcagcc
    15361 aacgcaaaat tccctcctga tccgatagct aagataccat catctggtgt gataacttct
    15421 cctgtacctg aaacaagaag catttcttta tcattcatta cgatcagcat cgcttcaagt
    15481 ttttgcatag attgctgtgt ccgccattct tgagctaatt cgacagctgc gcgttgtaga
    15541 ttcccgttat attcgtttag tttgccttca aatttttctt ctaaagtaaa cgcatctgca
    15601 acacttccgg cgaaacctac aacaacttct ccattgtaga tacgtcgtac tttctttgca
    15661 gtgcctttca tgacaacaga ttcacccatt gttacttggc catctccagc catagcaaat
    15721 ttcccgtctt tttcgacggc acagatagtg gttgaatgaa atggtgattc gaccatgttt
    15781 gtttcctcct aaatttgttc ttttccttat ttttacgctc ttggatggaa agaacgatag
    15841 tttttttgta aactttcttt tgttacatgg gcatagatct gggtagtcga taaattggca
    15901 tgtcctagca attcttggac tgtccgcaaa tctgccccat tatttaataa atgagtagca
    15961 aatgtatggc gcagcatgtg aggatggata tcactatcca aactgctttt tttgatcatt
    16021 tgattcaaga catattcaat tccagtaggc gtgattggtt ttccatgatg attcacaaaa
    16081 acgatatcat gctcttcgtg atattttgtc atcaatacct ggcggccttc cctgaaatat
    16141 tcttgcagag catcttgagc aaaagaacct agaggagcat atctctcttt gttcccttta
    16201 ccatggatca acatgacctc tgaatcaaaa tcaatgtctg ataccgacaa actgctacac
    16261 tcacttaaac ggatgcctga cccgtaaagg acttccagta aagcgcggtt cctcaaatcc
    16321 aaaggactat ctcctgctac gctgtcaaaa agtgcttgca tttcattttc ataaaaaaaa
    16381 cgtggcagtc tcaaattttt ctttttgaga tgaacgtaag aaaatggatt ttcttttatc
    16441 acttcttctt tgagaagata ctgataaaac gaacgtaggc tggctatctt gcgactgata
    16501 gaatttctgc tatagctagg acgatgatca gctaatgcac tcaaatagac acgaaccgta
    16561 aaatattccg ccttcagcag atcagcgtct ccagattcct ccaaaaaatg tttgaaatgg
    16621 agaatgtctt cttcatatgc ttctttcgtt ttttctgaat atcctctttc gacaatcaaa
    16681 taacgcaaaa atttttgttc ccacgtggct tctgtcattt tctcaccttc cttttgtccc
    16741 agagaataat ttagcacagc gtttataaaa agacaaataa attgtcagaa tttaaccaat
    16801 atttctaagt ttgttcacaa ttggcgcaat tcctcacatt ttgtttgaga aattcttaag
    16861 aaaaacgcaa gaaaaagagc gagactatcc gtctcaccct cttcatggag tttccttact
    16921 catttgggat tgcagttttt tctaattctg tttttattgc ctcattagct tttaaagctc
    16981 gttgtgcaat tgcttcatat cttgcttttt tgtctcgaat gcgctctggc agttcaggaa
    17041 acagaccata gttggcattc atcggttgga aatgttttcc ttccgcatga gtaatgtagt
    17101 aagccatact tccaatagct gtttcttgtg gaaactcgac tggttccatt tcttttgcta
    17161 agcgtgcggc gttgattcca gcaagtagtc cgctcgctgc actttcaaca tagccttcta
    17221 caccagtcat ctgacctgca aagaacagat cttcgcgttt cgttgattgg taagtcggtt
    17281 tcagcaattc tggcgaattc ataaagctgt ttcggtgcat cacaccatag cgaacgaatt
    17341 cagcattttc taacccagga atcatccgga aaacacgttt ttgctcgccc catttcaagt
    17401 gagtctgaaa gcccacgatg ttgtataaag aagctgcagc attgtcttga cgcagctgga
    17461 taacagcata aggacgtttg ccagttttag gatcttccaa tccaactggt ttcataggtc
    17521 cgaaaagcat cgttttgaat cctcgctgtg ccattacttc aattggcata catccttcaa
    17581 aatatttttc tttctcaaaa gatttaagtt ctgccacttc ggcattgatt agtgcctcat
    17641 ggaaagcttt gaattcctct tctgtcatcg gacagttcaa gtaagctgct tctcctttgt
    17701 catagcggga cttcaaatat actttatcca tatcgatcgt agctttgtct acgattggtg
    17761 cagctgcatc atagaaataa aaaccatctg aaccattgaa tgctttgatg ctttctgcta
    17821 atggatgaga agtcaaaggt cctgttgcta ctacggtgat tccttccggt atttcagtaa
    17881 tttcttcgtt tatcactgtt actaatggat gctctttgac ttttcgggta attgtttcag
    17941 aaaaagaatc gcggtcaaca gctaaggcac caccagctgg cactgctgtt tcatctgccg
    18001 aagtgattac taccgaattc aatcggcgca tttcttcttt caataaccct actgcattag
    18061 ccaaactgtt tcctcttaat gaattggaac atactagttc agcaaaatta cttgtgtgat
    18121 gcgcctcagt cgatttgact ggacgcattt catataaacg gacagggact cctgcttgtg
    18181 cgatctgcca agcagcttca cttccggcaa gccctgctcc aacaacattt accattttca
    18241 atgaaagaac ctcttttcta ttatttttgg atgtcttctt cgtaatctcc atttacacag
    18301 actacttgtt taccgccttt gactttcttc tcgaccagat atccgtcaca ttttggacaa
    18361 tttctgccca ctggtttatc ccaagaagtg aattcacatt ctgggaaacg ggaacaacca
    18421 tagaatagtc tgtttttctt agattttcgt tcaatgactt gtccttcatg acatactggg
    18481 caagtcacac cgatttcttt tacgattggt ttcgtattcc gacaatcagg aaaattactg
    18541 caagcataaa acttcccata tttccctaat tttatcacca tcggatgtcc acagacatca
    18601 caatcgaatc ctgctggttc atctttgatt tgaatttttt cgattttttc ttccgcattc
    18661 gtcagttctt tttcaaacgg tttatagaaa cgatcaacca ctttgaccca cgcttccgtg
    18721 ccttcttcaa ttttatccaa atctccttcc atttctgctg tgaaatggat atcgacgatt
    18781 tgagggaaga attcacagat taatgaattg acaatttctc ctagttcagt cggctcaaat
    18841 cttttttgtg tcaattttac atagtagcgt ctttggatcg tatcaagtgt tggtgcataa
    18901 gtggaaggtc gccctacccc gttttcttct agtgcacgaa tcaacgtagc ctcactaaaa
    18961 cgtgctggtg gttgagtaaa atgttgtttt ggttcaatat caacagattg gactacatcg
    19021 ccttcttcaa gttctggaag aatattttct ttctcttctt tgccgtcatc tctaccttcc
    19081 acatacactt gcatgaatcc tttgaatttg atttttgaac cgttcgcaat gaagatgaca
    19141 ccattttgtt ctaatgtcac tttcattgta tctaaaatag ctggtgtcat ctgactagcc
    19201 acaaaacgtg accagatcaa tgtataaagt ttcaattgat ctttatctaa atattgtttg
    19261 agttcatctg gtgtacgaag cacactcgtt ggacgcacag cttcatgggc atcttgtgcg
    19321 ccttgagcat ttttgatctt tcggtgacca tgtctagaaa attcttttcc atacgtatct
    19381 tcaataaatg ctgcggcctc tgcttttgct gtatcggcaa tccgggtaga atcagtacgc
    19441 atgtatgtaa tcaagccgac tgttccttgt ttacccaaag tgattccttc atataattgc
    19501 tgtgctacca tcatggtttt tcttgttcga aagtttaact tacgggcagc ttcttgttgc
    19561 aggctacttg tagtgaaagg attcgcaggg tttcttttgc gctctttctt ttctactttt
    19621 ttaacttcga agtctgttcc atcaattcta gcagtgactt cttttacact ttgtgcatct
    19681 ggtaatttct ttttcttacc gtcgattccc cagaaatttg ctttgaattt cttgcgagct
    19741 tttttaaaat taccgtcgat gctccaatat tcttctggaa caaattctcg gatctctttt
    19801 tcacggtcaa taataatttt taaagcgaca gattggacac gtcctgcact taaccctttc
    19861 ttgaccttac gccagagaat aggactgatc gaataaccaa cgattctgtc taaggtacga
    19921 cgagcttgct gtgcatctac taaatctaca tcgatcgttc ttggttcctt aaaagctgct
    19981 ttgactgcgt cttttgtgat ttcattgaag accacccgat ttttttcttt cagatccaac
    20041 ccaagtaggt acgctaaatg ccaagcaatc gcttctcctt ctctatccgg gtcacttgcc
    20101 aagtaaactt tttgagcttt ttttgctgcg gctttcaggc ttttgatgac atcgcctttt
    20161 ccgcgtatag aaatataatg gggttcataa ttgttttcaa aatcgatacc cattttactt
    20221 ttcggtaaat ctcttatatg gccaacactg gccattactt tatagtttcg tccaagatat
    20281 ttctcaattg tcttggcttt tgcaggtgat tctacaatca ctaaatattt atacgccatt
    20341 actgaatgga ctcctttcca ttgtcgtgtt cctactatta aaagaggatt catacaaatc
    20401 gtagctaatc atatccattc agaaaacgtt tgtcaagaaa agcaaatgaa aagtatggtg
    20461 ttattcttta aattctgcca agatatcttc acccgaaacc gtgcaaactg caccgtcttg
    20521 gatcaaatga tgacatccgg tagaatgttc tgttaaaata tttcctggaa cagaaaaaac
    20581 tgttcttcca agatccaatg cttgctgtgc tgttatcaga gagccgcttt ttttcttggc
    20641 ttcaaagaca catgttcctt tagacaaagc tgcgataatc cgatttctca ttggaaaaca
    20701 atgctttttc gggccggatt gaggaggata ttcactcaaa agaagatgat catttgcaat
    20761 cacctcttgc aagtcacgat tttcagcagg atagacttgc tctatccctg ttccaatgac
    20821 tgcgattgtc cgtccaccat gagagattgc tgcttggtga ccgtatgtat ctatcccttt
    20881 cgcgcagcca ctgacgatca catatccagc ttctatcact ggttttagta aataataaac
    20941 tgtttttttg gctaaagcag aagtgtgtct tccaccaaca acgcttaaca tgttacaaga
    21001 aagtaaagat agatcaccat tataaaacag tacaattggc ggataggtca agtgaagcag
    21061 ctgaggggga tatttgggat caaagcaagt gataaacgac tgtttcgatt ggattttgcc
    21121 ccagttagcg tgaatttcct gccaactttt gcgaaacagc tcccggtgtt tggttatttt
    21181 acctatctta atgatgtctt caaatccgat ttctttataa ggatactgca tcatccagtt
    21241 agcaagtgcc cattttcctt gactactgat tccttttgta taagcaagtt tcaataaatt
    21301 ttcttctatt tgatacatca taaaaccgcc tttcgtctct ctttctaata agatacgtaa
    21361 aagcggctgt tttttattgt aaatattttt ttacaggtgc aaaactttta cgatggattg
    21421 gcgtaattcc ttgtcgttca agtccttcta agtgttcctt tgttccataa cctgcattat
    21481 gcgagaaacc atatccagga taaagcacgt catattcttt catcaattgg tctcgatata
    21541 ctttagcaat gatacttgca gcagcaatcg acacagatcg tgcatcccct ttgattattt
    21601 tttcctgctg aataggcaaa tccaaggtca tcgcatcgat caacaaatag cttggtacaa
    21661 tggacaattt ttctactgct tggatcatcg ctaatttact tgcttcataa atattcacat
    21721 catcgattgt ctgctgatca acgatcccga tcccgattgc cagggctttt tcttgaactt
    21781 gttgataaag aagttctcgc tttttctctg ataattgttt ggagtcattc agccctaata
    21841 tgatctcatt tttcggcaag ataactgcag ctgccacgac aggtccagct aatggtcctc
    21901 ttcctacttc atcaatgccg gcaatccatt ggtgaccttg tgcgtaccct tgcttttcaa
    21961 agcaaaacat ttcttcatat ttttccttaa ttaatgcttc ctttttcaat cgtcgttcaa
    22021 aagaagccag tgcttgctgc acgcctttgc gtggatcatt tcttaatgat tctagtgtag
    22081 gatcatctat tctctgtatg cttttcaatc gttctttgat actttggatg gattcagtca
    22141 tcactttttt gctccatttc ttcgcaacga tccagtgtgt atcgtccaag ttttccttga
    22201 cgaatatcat gcacgactaa ttcgctgcca cgatcatagt cttctttata cccacgtttt
    22261 gctgtaatat ccatcagtaa ttccggtgcc aatttttctt cttgctcgat tgataaacca
    22321 taacgatcgc tgattcttcc tgaataatat cgggcaaaaa agtctaatcc gtaaatcgct
    22381 aaatcatcta aatggacaag ctggtctttg atcgcgcctg tcagcgctag ttttttgccg
    22441 atttcttcat cttcaaattt gggccataaa atccctggtg tgtctaacaa ttccaactca
    22501 ttacctaaac gaagccactg ctgacctttt gttacgccag gcttatttcc tgtctgtgca
    22561 attttcttgc ctactagtcg attcatcaac gtagatttcc caacatttgg aatacctaag
    22621 accattgccc gaatagcgcg aggcttgatc ccccgagcag catctcttgc ccgtttttct
    22681 ttcaatgctt ctttagccgc aggtactaga cctttaattc ctttactttc ttgtgccgtg
    22741 atagctaatg caagatggcc ttgtttacga aaatattctt gccacagctt tgtctgttgt
    22801 ggatctgcca gatccgcttt attcaataaa acaaggcgag gtttttgctg aatgatctga
    22861 tctagcattg gattacgaga agataaaggt aatcgtgcgt ctaccaattc aaatacgatg
    22921 tccacatatt tcattttttc agaaacttct cgtcgggctt ttgccatatg tcccggaaac
    22981 cattggatgg tcattgttct ctccattcct ttcataccgg aatattcccc ggctttactt
    23041 gtttttttct ttttcaatat aaattcactt ttttattatc ttaattgtca aattaagtta
    23101 gacaaatcat caatacttac gtaactcaaa aatacttcca aaggtgttcg ataattcagt
    23161 gattttctag gaatattatt tcgtttcgat gcgacagatt gaataaaaga ttcatctact
    23221 gaattgaaat ccatagattt caataaacca tctctacgta acaatccgtt agaattctcg
    23281 tttaggcctc tttgagacgg cgttcctgga tcagcgaaat aaatggcaat atcattggca
    23341 ttactgatct gtttccaatt tgaaaattcc tttccacaat caaaagtgat ggatttgaat
    23401 agatttttcg gtacagattc aaaccaatga tttaatttgt tttcaatatc aatcgcttgt
    23461 ctaccacacg gtttcaatgt gatgataact tttgataatc gctcaactaa ggtaattaca
    23521 gcacttttat gtttcaaacc tacgatagtg tcaccttcaa ggtgaccaaa ctcatttgag
    23581 aattggctat aatctttttc acgttcatga atagagcgac ggaaagcttg ttttccacgt
    23641 ctttcttgat gtccatttgg tttacgcttg cctttcatcg gtaagtcaga aggattaaat
    23701 agcccctttt tgaacatacg ataaatggta cgagcagaac aacgaatagg aaacgctgca
    23761 cgaccaacaa tcacatcggg tgtccatcct tgaacaacct ttctttgaat atattctgat
    23821 tgttcctcag gtaaaacaag cgggcgtcta ccacagtttg atttgttttt cttatactgt
    23881 tgatagtact ctaaggctga ttttc
//
LOCUS       DAPBBV010000045        23673 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.045, whole genome shotgun sequence.
ACCESSION   DAPBBV010000045 DAPBBV010000000
VERSION     DAPBBV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.045"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            288..695
                     /locus_tag="RD486_002163"
     CDS             288..695
                     /locus_tag="RD486_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663884.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            709..1110
                     /locus_tag="RD486_002164"
     CDS             709..1110
                     /locus_tag="RD486_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663885.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1112..1483
                     /locus_tag="RD486_002165"
     CDS             1112..1483
                     /locus_tag="RD486_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663886.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1519..1821)
                     /locus_tag="RD486_002166"
     CDS             complement(1519..1821)
                     /locus_tag="RD486_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663887.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2070..2270)
                     /locus_tag="RD486_002167"
     CDS             complement(2070..2270)
                     /locus_tag="RD486_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7663888.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(2575..3807)
                     /locus_tag="RD486_002168"
     CDS             complement(2575..3807)
                     /locus_tag="RD486_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDT7663889.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4061..4630
                     /locus_tag="RD486_002169"
     CDS             4061..4630
                     /locus_tag="RD486_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7663890.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4808..5248)
                     /locus_tag="RD486_002170"
     CDS             complement(4808..5248)
                     /locus_tag="RD486_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDT7663891.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5406..6170
                     /gene="map"
                     /locus_tag="RD486_002171"
     CDS             5406..6170
                     /gene="map"
                     /locus_tag="RD486_002171"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDT7663892.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6202..7125
                     /locus_tag="RD486_002172"
     CDS             6202..7125
                     /locus_tag="RD486_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDT7663893.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7201..8340
                     /locus_tag="RD486_002173"
     CDS             7201..8340
                     /locus_tag="RD486_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HDT7663894.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8333..9133
                     /locus_tag="RD486_002174"
     CDS             8333..9133
                     /locus_tag="RD486_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7663895.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9133..9960
                     /locus_tag="RD486_002175"
     CDS             9133..9960
                     /locus_tag="RD486_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7663896.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9938..10672
                     /locus_tag="RD486_002176"
     CDS             9938..10672
                     /locus_tag="RD486_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7663897.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            10772..11638
                     /gene="rfbA"
                     /locus_tag="RD486_002177"
     CDS             10772..11638
                     /gene="rfbA"
                     /locus_tag="RD486_002177"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDT7663898.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11652..12224
                     /gene="rfbC"
                     /locus_tag="RD486_002178"
     CDS             11652..12224
                     /gene="rfbC"
                     /locus_tag="RD486_002178"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDT7663899.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12246..13274
                     /gene="rfbB"
                     /locus_tag="RD486_002179"
     CDS             12246..13274
                     /gene="rfbB"
                     /locus_tag="RD486_002179"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDT7663900.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13372..14223
                     /gene="rfbD"
                     /locus_tag="RD486_002180"
     CDS             13372..14223
                     /gene="rfbD"
                     /locus_tag="RD486_002180"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDT7663901.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14258..16291
                     /locus_tag="RD486_002181"
     CDS             14258..16291
                     /locus_tag="RD486_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663902.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16335..17615
                     /locus_tag="RD486_002182"
     CDS             16335..17615
                     /locus_tag="RD486_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HDT7663903.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17825..18631
                     /locus_tag="RD486_002183"
     CDS             17825..18631
                     /locus_tag="RD486_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663904.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18643..19863
                     /locus_tag="RD486_002184"
     CDS             18643..19863
                     /locus_tag="RD486_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663905.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19853..21439
                     /locus_tag="RD486_002185"
     CDS             19853..21439
                     /locus_tag="RD486_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7663906.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21478..23616
                     /locus_tag="RD486_002186"
     CDS             21478..23616
                     /locus_tag="RD486_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7663907.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7569 a         3939 c         4853 g         7312 t
ORIGIN      
        1 ttgaggggaa gtacatatag ttgttgatat agttgctaat attgttagct aatttgttag
       61 taaaactgta tacgaattta gatagtaaaa aaacagtttg ttccttatat agaggcactt
      121 ttactactga ttaaatgtca gatatgctta caaatatact tataaatatg cttacaaaat
      181 tagctaatat ttccgttgac aaagctttgt tactattgtt aaactaaatt gactagcaaa
      241 agtgaaacat aaatttatta aataaatgta aaaattagga gaaatcaatg tcttatagag
      301 tacaattaat aatttcagaa gatgtagaaa gtcagcaatt tggcactaat gttattaata
      361 aagtaattaa tccagctctt tctattaatg cgcctttaat tcctactgct ttatcatttt
      421 ctgtaacagc tgtggtgtct gagatagagg atacagaaaa gataaaaata gtagaaattg
      481 aagttttaaa caagaatgaa aaacaaattt tttctacggg tgaagtatcg gtaagcttgc
      541 ctcctcaagt taacgatata aactttaata taaacgccag aaatgtcttg gttgaagaag
      601 caggagagca ttatgctgtt gttaaattta atggaactga gattggaagg caaatctttg
      661 atatcaaggt caacaaacca gtggaaaaaa attaaggaga cgatacggat gcttgatata
      721 gtaccatcaa atacacatcg gagtggtagc ttaataaatt ttgctgcgat ttttgcttgc
      781 gcatcggtaa ttctagcatc tccagttgtt gtggatgcaa gttctactcc gaaaactaaa
      841 aatgataatc aacttgtaat tactacaaaa aatgagatta acacaatttc aagtaatgat
      901 ggcaaaattt ttgatgtgat aaatacggtt ttaaaaagaa aagctgaaat caatataaaa
      961 tatgatgaag atttaaactt gtatttcttt gttatcaaaa caacatctga attgttttcc
     1021 tcagattacg atgttttgga tactctcgat aatgtattat ctgactataa atatatgggg
     1081 aaatctgtag tagcaacttt gggggaataa aatgtttgac tttaatgaat atttatctat
     1141 ttccaaacaa attgaatcag atgataaata taattctaaa gaatcttata gaagaactgc
     1201 tgtttcaaga gcatactaca gtgcttttaa aaaatctgat gagtatttga aagaaaatta
     1261 tgatattatt tataatggaa gtagcggaaa aggaagccac caaaccgttt ggaatttgtt
     1321 ttcaacagtt aaggaattga ataccttagg aatacataat agtgggtata gaatgttaga
     1381 gaaaagaaaa tgtgctgact atattcctaa tgaaaccatt acgaaaacag atatggcgct
     1441 gatgaatcga gaagcagaaa aaataataaa caaactcacc taatgaattt caagcgagtt
     1501 tgtttgttat ttttttattt aatctttgta tctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatgat cgctacgtgc gtccggcacg tcagtcacga tatcaaacaa
     1621 aaagtataca cccttcttca ttctagtttt cgcagcagga attttgaaat agttcttatt
     1681 agaatagtag agattgatta ataagctatc ttcgattgct aaaaagaaaa cttctgaatt
     1741 ccatacttta taaaaatctt tgataaatct attcgaaggg tcaaatttaa accataattg
     1801 tgtttttcct tccatcagca taaaagttca cctcaaaaag agtatacgaa cgaatgttct
     1861 ttttgtgaag gcggaattta atatactgaa taatagaaaa caagtacttg tgccaaatta
     1921 tgtgccaaaa aaattcgaat tcaacaaaat gtaaacaaat agaaaacctt ctatattaag
     1981 atttcctgca ataacaaaca caacagaaga cgtgtaatag ttagtcagga acgtacaaat
     2041 aacccctgta tcctttgcgg tacagggggt tattttgtat aagtagacat tgtagtttct
     2101 aaactgctat gtcctaaacg tttcgatacg ctaagtatat ttactccttg ataaagtaaa
     2161 atagatgcat gcgtatgtct tagtccatca ataaacagtc gaagagaaaa tagggaaaaa
     2221 ttgattacta aagaaaaact tactaggtcg acggtgtagt tgattttcat acttcaatag
     2281 attcgaatta aacgatttcg attggcttat accagtccta tccaacgaaa gatatatcgt
     2341 tcttaactct agcggtataa cttgaagctt tacgtaaagc caatgggaat gaactggaga
     2401 tgacttttta ttatttttag taatagctga tgggttaata cttacaactt tccttttcaa
     2461 agtaccatat aaaaaaacgg tggggttgtt tagcgaaata aaggatctaa gccaatagct
     2521 tagatccttt attctatgct ttatattatt ttttgcatgt gtgcgaaagt atactcaagc
     2581 ccaatcgcca tttcggaaaa tcggtactgt agagccatct tcacggattc cgtcgatatc
     2641 catcttgtca gatcctacca tgaaatctac gtgggtttga cttctattca atccagcttc
     2701 tgctaattct tcatcggaca tttctgtacc gcctttcaca ctgaaggcat aagcagaacc
     2761 tagtgctaag tgattcgatg cgttttcatc aaataatgta ttgaaaaaga tgatgccaga
     2821 ttgagaaata ggtgaagggt caggtacaag tgcgacttct cctaaacgac gcgcaccttc
     2881 atctgtatca agcagttttg ctaagacatc ttctccttgt tcggcagaaa aatcaacaac
     2941 ttttccatct ttaaaagtaa atttcatacc cgagatgatg gtgccagcat aactcagtgg
     3001 ctttgtactt gaaatgtaac catctactcg atgactgtca ggtgctgtga acacttcttc
     3061 cgtcggcata tttgccatga atttttctcc acgagcatta tagcttccag cgccttccca
     3121 aagatggttt ttaggcaatc cgataatgat atctgtaccg ggagcagtat agtgaagggc
     3181 agaaaattgt tctcgattca attcttctgc tttttttgct aatttttcat catgcttctt
     3241 ccatgctaag acagggtctt cttcatagac acgagtcgtt ttgaaaatct gatcccataa
     3301 tgcctcaact tgtttttctt ctggcagttc tgggaagact tttgctgccc attgtttacc
     3361 agccgcagcc acgacagtcc aactgacttt atttgcttga gttgccttgc gtaaattcat
     3421 tagtgctttg ccattcgctg attgataaga cgctactcga tggctatcta caccagcaaa
     3481 tgcatcggga tcggcagaaa caacgctgat cctgcttgct cctttttcaa gccattcatc
     3541 cgcttgatcg attttagatt gtggtacatt ctcaatacga tccgttgcag catgtaaaag
     3601 aaattctctt tggatctggt cgtcagtcca ttgaacgata acctcagcgg ctcctagttt
     3661 ataagcttct tgtgtgatca atcgagcaag gggtgcctgt tccacgctga tctgtaaaac
     3721 aactgtgtgt cctttttctg tggctacgcc agtttctgca attaagcgtg catatttttt
     3781 tagaagttca ttaaaatcag ataacataat aaaaattcct cctcaccatt ttttctggta
     3841 actattagca tgataccatt taattatgat tcaaacaatg aggctttaaa taaaaaaagg
     3901 aggttatttt tttaaggtta agtttcatga tatatgttac tacttgctat ttcagcttgt
     3961 gaagaaaatc aaaaactaat tttgcatatc aaaaaaacat gttacaatga aattaatcaa
     4021 tggtggaagc gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat
     4081 tactagagaa cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg
     4141 atttactgcg agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga
     4201 gtttaaaaat atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca
     4261 atatgaagtg ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta
     4321 tatccatttt gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg
     4381 tggaggaaaa gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga
     4441 tccagcttat gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat
     4501 catagctact gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca
     4561 gattgaaaag atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga
     4621 aatcgattga atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa
     4681 taaggaaaag ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca
     4741 tgaatgcaat gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc
     4801 aagtatatta aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt
     4861 cttcttcagc attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg
     4921 caaaagcagc atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag
     4981 atccgcagac accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt
     5041 ctacgatctc atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat
     5101 ctgcctcctc gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat
     5161 ccagattttc aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc
     5221 tagcatatac gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa
     5281 ttatgaatta taccaaaaca tcattgaaaa gaaaataaaa cctaaagaca cctggggaat
     5341 gtcatttggc taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg
     5401 aaaatatgat tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt
     5461 tattagcaga tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg
     5521 atattgaggt atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg
     5581 gctttgaagg gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat
     5641 tccctcgtaa aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt
     5701 tgaaaggcgg catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga
     5761 tcgaccgatt gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag
     5821 tagggaatcg gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc
     5881 tagcgatcgt tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag
     5941 cagttcctca ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca
     6001 cgatcgaacc tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga
     6061 ctgcgtatac aagagacggc ggactttctt gccaatatga acatacattg gctattacta
     6121 aagatggtcc aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt
     6181 caataggtac gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg
     6241 atgcgcttta ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct
     6301 gtcgtcgttg cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat
     6361 attttaccgt ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt
     6421 cctgagaccg tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca
     6481 ggaggcttgt tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat
     6541 gctttgcaaa ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc
     6601 gtccgtttct tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact
     6661 atcgttcttg ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc
     6721 gtgaacttta tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt
     6781 gtcatcatgt tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc
     6841 attccgggca cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc
     6901 tatgctaggt attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta
     6961 ctcatgcttt ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca
     7021 gttgttcaag aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa
     7081 tggttcaata aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta
     7141 ttgtaaattt atatcagtaa tttataataa ttatgactct taattaaagt aggtgcccat
     7201 atgcttgttt cttttagtat ggttataaga ttttttctga caattttatt atcactgata
     7261 ttaacacctg tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa
     7321 agaagaataa ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt
     7381 gttatatcga ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc
     7441 ttgattgctt ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca
     7501 cctaaacaaa aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat
     7561 atacgtattg attccttcac gcttcctttt attggatata tccaactagg ctggcttagt
     7621 tttcccgtaa cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt
     7681 ttggatgggc tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga
     7741 tattttttcc tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca
     7801 agtattatcg gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca
     7861 ggagctctat tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg
     7921 acttttgttt catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt
     7981 tttgctatca ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat
     8041 cttcatcacc gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat
     8101 gcgatggctt tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga
     8161 acgatcatat tgattattgc catgttgttt gctgcaattt tattatttga attgattggt
     8221 ctgatcaatg agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag
     8281 taccgtacgc aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa
     8341 caaattaaac cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg
     8401 gacactagat aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt
     8461 tgacaacaat tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta
     8521 catcgatatc tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct
     8581 gatagctagc gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga
     8641 gacagttaca gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc
     8701 taagattctt aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt
     8761 tgattacgtt ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact
     8821 ggctgtgttt gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc
     8881 aggtagtttt atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg
     8941 tttcttcatg tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa
     9001 gttattgtac acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa
     9061 tgcaaaactg tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg
     9121 gcgttttttc tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc
     9181 agtcaatctc cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt
     9241 attatttacg ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc
     9301 gtttatcatc atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct
     9361 caagcagatg aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac
     9421 gattattttg aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg
     9481 atgatttttt ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt
     9541 acagctcaag cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca
     9601 ggtgttgcct ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct
     9661 ttagattttt tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag
     9721 atccttcctg tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt
     9781 aatcgatacc gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg
     9841 catttatcca gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc
     9901 aaaaaccggc atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga
     9961 attcgtgcgt tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt
    10021 agatagtatt ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc
    10081 agtagatgat acatgggata tattaactga atacgcagaa aaagataagc gaatccagct
    10141 tttttcgggg cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa
    10201 aggagatcta atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa
    10261 gatcactgac tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat
    10321 tgtggacagc gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga
    10381 aggatggctt aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc
    10441 ttctttaaaa cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat
    10501 tggtttgctg ggaggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag
    10561 acatgattta aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg
    10621 gcgtgttcat ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat
    10681 gtttaaatcc ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga
    10741 aatttgaaat caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag
    10801 cggaacacgt ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga
    10861 caaaccaatg atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct
    10921 gattatttca acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga
    10981 tttaggactg cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt
    11041 tatcattgga gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat
    11101 ttactatggt ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc
    11161 gacagtattt ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga
    11221 gaatatgcaa gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt
    11281 aactggcctt tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc
    11341 agaacgtgga gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact
    11401 atccgtagaa cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt
    11461 gcttgaagca tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg
    11521 tttggaagaa attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc
    11581 acagccattg aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg
    11641 agtccttaca gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg
    11701 acgtctttgg cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag
    11761 aacatggatt gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg
    11821 tccttcgggg gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag
    11881 tcactggagc agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc
    11941 aatgggacgg atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat
    12001 atgcccatgg attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt
    12061 actataatgc agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt
    12121 ggccaattga tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa
    12181 aagaatttga agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt
    12241 ttcttatgaa aaacatcatt gtaaccggag gtgccggatt catcggctct aatttcgttc
    12301 attacgtggt aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg
    12361 caggaaacaa agagaacttg gccggacttc ctagcgatcg cgtagaattg gtcgtaggag
    12421 atgttgcaga tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt
    12481 acgcggcaga atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga
    12541 atatcattgg tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc
    12601 acgtatctac tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg
    12661 gggaaggcga aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt
    12721 cttctacaaa agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac
    12781 gtgcaaccat ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta
    12841 ttcctcgcca agtaacgagt atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa
    12901 agaatgttcg tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga
    12961 cgaaaggcag aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga
    13021 ccgtgatgga attgatctta gaaatgatgg gccaaccaaa agacgcatac gaccatgtaa
    13081 acgaccgcgc agggcacgat ttgcgttatg caatcgattc gacaaaattg cgagaagagc
    13141 taggttggca gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt
    13201 acgaagaaca tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca
    13261 aaaatggaca ataatacaga ggaaatttca ctgtattaat ggaaaaacac atgtgaggca
    13321 ggcgctcgcc tgtctctttt ttaaaataaa aatcaaggag cggataacca tatgttttta
    13381 ttaactggag gaaatggaca attaggtaca gaattgcgcc atttattaga tgaaaaaaat
    13441 ctgccatatg tttcaacaga tgcaaaagac ttggatatca cagatgctga gaaaacaatg
    13501 gcttatatta cagaattaaa acccgatgtt attttccatt gcgcagctta cacagcagta
    13561 gataaagcag aagaagaagc aaaagaatta gatgagaaaa tcaatgtcga tggcacaaga
    13621 aatgtagcac ttgcagcaaa agctgtgaat gcacaattcg tctatatcag tacagactat
    13681 gttttcgatg gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta
    13741 aatgaatatg gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac
    13801 tattatatca tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg
    13861 atgcaacgcc tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga
    13921 ccaacttgga cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca
    13981 tttggtattt atcatttgtc gaacgaaaat agctgttctt ggtatgagtt cgcaaaagaa
    14041 atattgaaag atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa
    14101 gcaacacgtc cgcagtattc agtcatgagc ctgaaaaaga cagaagcgtt aggttttgtc
    14161 ataccaactt ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag
    14221 taatttcctt tttatcaaat agaatttgga gcatgatatg gaaaaacaaa caagaagtgc
    14281 acgacgaaaa gaaaagccaa aagcgaatca ggcagattcg aatttggtgc ttgacctgtt
    14341 tctaaaactc cgctatctta ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt
    14401 aaacggaagt tcacttggtg tttgggataa atatgtgtcg caaagagacg atgggaaaaa
    14461 aactgatgtg atttttggac agaatcggga agtgcggtca gacgaatggc tggtgcagac
    14521 acctttttac ctctcacaag ctgaagagga cttttcgttg gtgaacgagg attattcatt
    14581 aaacggacaa aacatgatca ttgcgtataa ttctcctgta aaggatatta cggttatcgg
    14641 aaaaccattc aactggggat tctttttcct cggaagagat cgaggacttt ccttttattg
    14701 ggcgatgaaa ttagtcgtca tggtcttgct tggattcgaa gtactgatga tattaacgaa
    14761 gaggaaaaaa gctctatcgc taatcggtgc atttgcgctg acattttctc cagcagtcca
    14821 gtggtggttc atgcaacatg tgggcgattt gattttcttt actttgggac tgatgattgc
    14881 tttttatcat tatttctaca atcatgataa aaaatggcta cgaacgttga tgatgctttt
    14941 ggtggttatt ttcggtattg ggtttatttt agtgatttac ccagcccatc aagtgatgct
    15001 ggcgtacttg ctgatttttt attttgttgg cctgcttatt tactatagca agaaagtttc
    15061 atgggatctg ttggatgtag tgttgattgg aggggcagtt ttatttattg gcggagtcat
    15121 ggttcatttc tggctaacgt caaaagacgc attgttagct tctttgaata ccttatatcc
    15181 aggaaaacgg gtaagtactg gaggaaagtg gacgattggc gaattttttt ctttccttac
    15241 aaattggaaa attccttttg aagatatcaa ctattcgaat aactctgaag tggccctgtt
    15301 ctatcacttt tttccaactg tattcctagc aagtccattt gtgttatttg gcaaaaaaga
    15361 tagcgaacaa aagttactgg gacgtatttt gatgattttt tgtctgtttt ctatcttttg
    15421 gattaccgtt gggttgccaa aatggctagc agaaatcact ctgctgtctt atgttcctcc
    15481 attaagagcc atccttactt ttagttttgc ggcttgttta ttatcgatct ggtttatcgc
    15541 ttatatttgg agagaagatg ttattcctat ttggtataaa ttcattttgt tggcagtaaa
    15601 tgcatggtct tatttctatg cgattacgca ttcgaaaatg gataattatt tttcggattt
    15661 tgaaaccatc gcagttgctg tgttgggaac agtgatttta gcttttgcat tatttggctg
    15721 gagacgcttg ttttacctcg cttttgtcgc cttagttatc gtatctggct ttttcgtcaa
    15781 tccagtcgta gaaggtacag gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa
    15841 aatcgatcaa caagatcctg gtaaagtttg gttgtctgaa gatgaattat ataacttcac
    15901 cccaacattg ggagtgaaat ccttcaatac agtacgcttt tatccagata tagctgcatg
    15961 gaagaaaatc gatccgaaag aagaatacga gaagtattat aatcggtatg ctcatacaag
    16021 agcttttatc gctaaggaag atacaaagtt cattttagat cgtccagata tgttttcggt
    16081 cacgttgaat tttgaagacg cagaaaaatt agggatcgac tatgtgatca gtaaacgacc
    16141 attaactgat tacaaccaat tatatgaagc gcagttcacg cagctatatg gaccggataa
    16201 agacggttat atgattttta aagtagaata tccggattat ccagatgtac cacaaacaca
    16261 aactcaggaa aatcagctag tcgtacagta ataggctagc tgagaataat cctgaaatat
    16321 tagtagaaag gagagtgaag ataattcaag caatcgtaca aaaatttgtc aacaaaatga
    16381 gtgtcggttt cttgcttttg ttgctgacgc tagtcttttt tgtttggaca gcaggggtag
    16441 gttttccagc aactttgttt atatataaca atagttcatt acttatcgct tttagtgtgg
    16501 ctattttgct cattttaaat gtttataaag caaaaggcgt cgattttctt tatctaggtg
    16561 ttgcgcttgc ccttttcatt ttcttttctt actttcggga attaagaaat gagtctttat
    16621 ttggagactt actgtttcct ttgattattt tattttgttt agtaattaaa tggatcgagt
    16681 ggacaaaatg ggatcgcggt atttatctga ttgtctttac ggtcttcctc ggaatcacgt
    16741 tatatcgtgt atttacagag atccaagtac cagaaggaca aagcatctgg gctccaggca
    16801 attcgctttc tgatatttgg atcaatacga atacaatcgg aagttctttg atgactcttg
    16861 ctttattgat cagtggattt gccagttctt ttgaacgatg gtatgttcga atcatcggtg
    16921 ggatagcagt cgttgcagcc tttttaggta tttgggtctg ccaatctaga ggtgcattag
    16981 tcgcgttgat tgtttttgcg atattggatc ttttacctaa atcgttgatg cgtgtcattc
    17041 gtgcgccatt tattgcctac acggttacga ttcttttagc tttgccgatt tcttatctgg
    17101 cggctgtctc tgaaaaagtc aatttgttta ccggtcgaga agatatttgg cataaattct
    17161 atcagacgct aggagaaaaa tctgaacaag ttttactagg aatgaaaaca tttatcttcc
    17221 agcgaggaaa ccaattttta ggaaaccaca atagttataa ttctattttg aatatctatg
    17281 gattgatagg atttgggatt gctgctttgc tgcttatcct ttttattggt cgcttaacgt
    17341 tgaaagcaga tttatccaac gggcagatga cttttatctg ggcctttttt gcggtgatga
    17401 tgcagtcatt tatggaggat acattgactt cataccgatg ggttccgatt atttatatcc
    17461 tgttggctat ggccgttcat cgatatgatg aaccagaagt tacggaggaa ttctatgtta
    17521 tggaagaggc atatgacgat atgacttatg atgatacatc ttatgaggaa caaccagata
    17581 gcgctcattc ttccaggatc caacgctatc attgataggc acaaaatacg agagaggctg
    17641 tgacaaccgt cgcagccttt tttggtttat tgcaattgtc tagcatcttc tgtaaaatag
    17701 aaacgttaga gaaaatcttg tatcatagaa aattaagaaa gaaataagaa cgcagctcgg
    17761 taccaaaaat atggtaaaat ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac
    17821 acaaatgttt aaagatttgt atttatttat gaaggacatt tatcagaaca gaaaattact
    17881 gctacagttt tcgatcaatg acttcaaatc aagatatgca ggatcgtttt taggaatctt
    17941 atgggcgttt atcaatccgc tatttactgt attgatttat tggctggtat ttggtgttgg
    18001 actgaaagca caaatgatcg atgcaaaata cccatttatc gtatatttag ttaccgggat
    18061 gattccctgg ttcttcttct cagatgcatt tgcatcaact acggttgttt ttcgggaata
    18121 tacttattta gtaaagaaag tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct
    18181 atccaatctg tacacccatt tattcttcat tctgattggc atagctgtcg cgcttataaa
    18241 tggtatatat ccttcagcaa tgtctttaca gctgatttat tatttatttt gcatgtgtgc
    18301 tttcttgaca ggattgactt ggctgacggc atcgatccaa ccatttttac ctgatatcat
    18361 gcaattaatt acgatcgtgc tgcagttgat catgtggaca ttaccgatat tatggagccc
    18421 taatcagttt gattcaggtc ttgtaagcat attgaaatta aatccgctgt actatgttgt
    18481 tcaaggttat cgtgagtcat ttttaagtga agcttggttc tgggagcatg gaacatatac
    18541 tttgtatttc tgggttttca cgttagtaat gttcgtaatc ggctctgcag tgttccgtag
    18601 attgaaacca catttttcag atgtgctgta aggagaatag ctatgacaga atatgcaatt
    18661 agactaaaag atatcacaaa atcttataat atgtacgcaa aaccttcgga tcgatttcgt
    18721 gaagccctca atccttttaa gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg
    18781 aatgtagaaa taaaaaaagg tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa
    18841 tctacaatgt tgaaaatcat tacgggagta ctgacaccaa catccggcac gatggaaatc
    18901 gaaggaaaaa tctcagcttt gctagaacta ggatcaggat tcaatcctga gtattctggc
    18961 tatgaaaata tctatttaaa tggaatggtt ctaggatttt caagagaaga agtcgatgaa
    19021 atggtcgatg atatcattga atttgctgac atcggcgacc atatttatca acctgtaaaa
    19081 acctattcaa gtgggatgtt cgttcgtcta gcttttgctg tagcgatcaa tgtgaatcct
    19141 gatattttga ttgtggatga agcattggca gtaggagatc ttgaatttca actaaaatgt
    19201 atggaaaaat ttacagaaat caagaactcg ggaaagacga ttttattcgt ttctcatgat
    19261 attagttcga ttcgccgttt ttgtgatcgt tcctattggt tgaaaaatgg aaaagttgtc
    19321 gaatatggtg atacgatgga agtaacgacg aattacgaaa actttttgaa gaaaaaatca
    19381 gttaaaacag tagatcgaaa taaaaaccaa gtagaacgct tcgcagctcc agatatcgta
    19441 gacgtgacga aagccgaatt gttggataaa gataaaaatc cagtggatat gctggaacaa
    19501 ggagaaaaac tatacgttaa agtaacctat gaagtaaaag acgatacaat caaaaatcca
    19561 gttttaggaa ttgctctgcg tacagtcgac aatttttatg tgtgcggact caatactcta
    19621 ctagatggta tcaagatccc ttggaaaaaa ggtgagaata tcttttatct ggagtatgaa
    19681 aagttaggtt tgttagctgg tgaatattat tttgacgttg cggtctttga agaaaatgca
    19741 acggttcctt tggtatacaa gacaaaatac atgaacttgt ttgtcagcgg ttcttatatc
    19801 ggagaaggca tcgtggtctt agaccataaa tgggaagaag ggactcatag caatgaaata
    19861 tgattttgaa atggacctag atgaacaaag cagtgtggga aaaattgccg cacagatcaa
    19921 accaggaagt aaagttttag agtttggtcc tggaaacggc cgattaacga aacatttgat
    19981 cggagcaaaa caatgtgaag tgagcattgt cgagctagat aaggaattgt tcgattttgt
    20041 cagcgagttt gcccaagatg gattttatgg agatatcgaa agttttgaat gggcaaacta
    20101 ttatgctgga caaacatttg attacgtttt gtttgccgat gttttagaac atttggtaga
    20161 tcctggaaaa acgttgaaga aagttagaga atttttgaat gaagaaggag aaattctaat
    20221 tacattccct aaccttgcgc ataattctgt catgattgat ttgttcaata atcaattgcc
    20281 atgggcttct tatggtttgc tagatgaaac ccataattct ttttatactc atgatggctt
    20341 ccaaaaagtt tttgaaaaag caggattata catcaatatt gaagattatt tgtacttagc
    20401 tgtaggtgat acagaattaa aatcaactta tgaagaattg ccggaagctg tacgttatga
    20461 tttcaaaatg cgaccatttg gcgaagtcta ccaatacttc ttctcattga tgaaacatcc
    20521 agtagcacaa agttccattg cgcagccgca aaattctaat tatgtgaaag tattagaagt
    20581 aatccagcaa acgaaacaag atgaaataat tcaacaaata ccattcaata atttcacagg
    20641 ggaaaatgag acactaagtt tccatgtatc agaattagca gaacgaatgg tgtttcgctt
    20701 cgcgcagcaa cctagcttta tcgaattcag cgcagaagct gctggagaaa aactcacatt
    20761 tatcgattca aatgctgtag tcaaaacagt aaatgattgt tatttgtttg atggtaaaga
    20821 tttaccagag ttctttttaa cggatattgc agggaaagaa gtgactatcc attgtcacta
    20881 tcgttttatc ggagaattga caccaacaat gaaagaattg ctggaaacaa tccgtccaat
    20941 ggctgaagtt acaaagcagc tttctgagaa aaatgatgaa ttagaaagag aaaatcatta
    21001 tcttattgag aataatacaa gattagatca gacgttgaaa acaaccataa atcgctattg
    21061 cacgttgttg gaaagtgatg aatggacaat caaacataga ttagggcgac gtaagaaaga
    21121 aacatcgaaa aaaatccaag aaaaagagct ttctctatgt attgacgaaa aaatctggga
    21181 tgcagaaaca aagatattga aaatcatcgg gtggggaatc gctaattcgg atcgccaacc
    21241 attgtcctat aagttatcag ccgaccaatc accatttttt gaagcaattc ctgttttacg
    21301 agaagaagtc aatcaagcaa aacagctagc tgaaggagca aaagcaggat ttgaactgcg
    21361 gatcctttgc gagaaggaac gttcattctt agttgaagca gtggctcaaa atggtcaatc
    21421 atggatcatt gaaatgtaaa taatgattaa cttataaaga taaggagtaa acgaatcgtg
    21481 caaaaaaaag aaattgccgt atttatcgat caaatcactc gtgaacgggc cactggcgat
    21541 ttgcttattg tgggctgggc aattgatgaa gtgaccaaag aaatccctac gataaaggta
    21601 gaaaaagaaa atgtgattgc tgaagcaaca catgtcgtaa gattggatat caatcattta
    21661 tataatcttg atgttaagac ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga
    21721 ggaaaagcaa tcttagactt ccaaacagca agacatcaaa atggcatagc tgtgaaatta
    21781 aacggtaaat atccttatga tgacggcatt gaatcttcat gggaaagaaa aaaaagatta
    21841 ctgaaaaaag ggataaatta tgcaaggact catggcgtaa aaaaagcaat ccgccgggtc
    21901 aaactggaat tgaaaccagg atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa
    21961 cctgatctga aagagcaaag gaaagaagta caaggatttg cctaccgccc attgatttcc
    22021 atacttatgc ctgtctataa cgttgaaatc aaatggctcg aaaaatgcat tgattcggta
    22081 cttgatcaaa cgtatgatca ctgggaacta tgtatcagtg atgatgcttc tactgatcca
    22141 gctatccgaa agtgtctaga atcctatcaa gcaaaagatg atagaattaa agtcgttttc
    22201 cgacaagaaa atggacacat cagtctggca actaattctg cattggaaat ggcagaagga
    22261 gagtttatag cgctcttaga taatgatgac gaattacctc catttgcctt atatgaagtg
    22321 gcaaaagtgc taaacgtaca tccagaactg gatttgatct acagtgacga agataaaatc
    22381 gatgcagatg ggaatcgctt tgacccgcac ttcaaagcag actggtctcc cgatacattg
    22441 atgggaaata attatatctc tcacttaggc gtatatcgga caagcattgt taaggaactt
    22501 ggcggtttcc gtaaaggata tgaaggctct caagattatg atttggttct tcgtgtgaca
    22561 gaacaaattc ctgcagaaca catttaccac attgaccgtg tcttgtatca ttggcggacg
    22621 atcccgggat caactgcaag caatggagaa gctaaaagct acatctatga ttctggagtg
    22681 aaagcattga cagatgctct atctagaaga aatatcaagg gaagcgtaca tcctggcaga
    22741 atttctggtt tttatgaaat cacttatgat gttttgcaag aagacttggt cagtgtgatc
    22801 attccaacta agaatggcta tgaagatcta aaaacttgtg tggattcgat catcgaaaaa
    22861 acgtcttatc caaattatga aatcattatt gcagataatg gaagtacaga tcctaaaatg
    22921 caagaattat ttgcagaata caagcatcag ctgaaagacc gatttatcgt cgaattaatt
    22981 gacattccat tcaattattc acgtatcaac aatctggcag cagaaaaagc aaacggcaaa
    23041 tactttttat tcttgaataa cgatacagaa gtgattgaac ctgactggat gacagcgatg
    23101 gtttcttatg cacagtttga tcgaatcggc tgtgtaggag caaaattatt ttatccggat
    23161 gatacaacgc agcatgcagg tgtattatta gggatcggtg gcgttgcagg acatgcattg
    23221 aataactatg atcgaacaca ttgtggttac tttggccgat tggtcattga cgtcaattac
    23281 ttagcagtca ctgcagcttg tatgatggtc aaggcagctg acttcaatgc tgtcaatgga
    23341 tttgatgaaa tattagaagt agcattcaac gatgttgact tgtgcttgaa agtttatgaa
    23401 ctgggtcgtt acaatgtcta tgcacatcaa gcagaattgt accatttcga atctaaatca
    23461 agaggttatg aagatacacc agaaaaacaa agacgttttg ctggggaaat caaaaaaatg
    23521 caagataagt ggccttctta tattgctcat gacccatttt ataacgataa tctaactaaa
    23581 gaaggaatcg gcgatttttc gttgagacct gattgattaa aagaactgta ttttcatttt
    23641 tattaatgaa aatacagttc ttttaattta att
//
LOCUS       DAPBBV010000046        23299 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.046, whole genome shotgun sequence.
ACCESSION   DAPBBV010000046 DAPBBV010000000
VERSION     DAPBBV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.046"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..2387)
                     /gene="esp"
                     /locus_tag="RD486_002187"
     CDS             complement(<1..2387)
                     /gene="esp"
                     /locus_tag="RD486_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HDT7663908.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVS"
     gene            complement(3004..3438)
                     /locus_tag="RD486_002188"
     CDS             complement(3004..3438)
                     /locus_tag="RD486_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663909.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3455..4102)
                     /locus_tag="RD486_002189"
                     /pseudo
     CDS             complement(3455..4102)
                     /locus_tag="RD486_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
     gene            complement(4307..5626)
                     /locus_tag="RD486_002190"
     CDS             complement(4307..5626)
                     /locus_tag="RD486_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HDT7663910.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(5783..6343)
                     /locus_tag="RD486_002191"
                     /pseudo
     CDS             complement(5783..6343)
                     /locus_tag="RD486_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
     gene            7037..7423
                     /locus_tag="RD486_002192"
     CDS             7037..7423
                     /locus_tag="RD486_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7663911.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            7517..7708
                     /locus_tag="RD486_002193"
     CDS             7517..7708
                     /locus_tag="RD486_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663912.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            8222..8554
                     /locus_tag="RD486_002194"
     CDS             8222..8554
                     /locus_tag="RD486_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7663913.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            8850..9005
                     /locus_tag="RD486_002195"
     CDS             8850..9005
                     /locus_tag="RD486_002195"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HDT7663914.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            9281..10621
                     /locus_tag="RD486_002196"
                     /pseudo
     CDS             9281..10621
                     /locus_tag="RD486_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(10862..12478)
                     /locus_tag="RD486_002197"
     CDS             complement(10862..12478)
                     /locus_tag="RD486_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDT7663915.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            12596..12814
                     /locus_tag="RD486_002198"
     CDS             12596..12814
                     /locus_tag="RD486_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663916.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            13009..13470
                     /locus_tag="RD486_002199"
     CDS             13009..13470
                     /locus_tag="RD486_002199"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7663917.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(13663..13902)
                     /locus_tag="RD486_002200"
     CDS             complement(13663..13902)
                     /locus_tag="RD486_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663918.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(13926..15449)
                     /locus_tag="RD486_002201"
     CDS             complement(13926..15449)
                     /locus_tag="RD486_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDT7663919.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(15467..15589)
                     /locus_tag="RD486_002202"
     CDS             complement(15467..15589)
                     /locus_tag="RD486_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDT7663920.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(15619..16602)
                     /locus_tag="RD486_002203"
     CDS             complement(15619..16602)
                     /locus_tag="RD486_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7663921.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(16626..16775)
                     /gene="rpmG"
                     /locus_tag="RD486_002204"
     CDS             complement(16626..16775)
                     /gene="rpmG"
                     /locus_tag="RD486_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7663922.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(16796..17173)
                     /locus_tag="RD486_002205"
     CDS             complement(16796..17173)
                     /locus_tag="RD486_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663923.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(17205..17384)
                     /gene="rpmF"
                     /locus_tag="RD486_002206"
     CDS             complement(17205..17384)
                     /gene="rpmF"
                     /locus_tag="RD486_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDT7663924.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(17399..17668)
                     /gene="rpsN"
                     /locus_tag="RD486_002207"
     CDS             complement(17399..17668)
                     /gene="rpsN"
                     /locus_tag="RD486_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDT7663925.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(18191..19957)
                     /locus_tag="RD486_002208"
     CDS             complement(18191..19957)
                     /locus_tag="RD486_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663926.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(19917..21671)
                     /locus_tag="RD486_002209"
     CDS             complement(19917..21671)
                     /locus_tag="RD486_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663927.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(21781..22350)
                     /locus_tag="RD486_002210"
     CDS             complement(21781..22350)
                     /locus_tag="RD486_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HDT7663928.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(22368..>23299)
                     /locus_tag="RD486_002211"
     CDS             complement(22368..>23299)
                     /locus_tag="RD486_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7663929.1"
                     /translation="IILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKE
                     LIDQVLFVKNRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEIT
                     YENILKDINFDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFL
                     VMQEMDYQFFTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRL
                     LVSIASLSKTNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCN
                     RIIYLKNGGIKKDIKLRVEDSTLIEQIFNDITK"
BASE COUNT         7438 a         4390 c         3497 g         7974 t
ORIGIN      
        1 aagcttacgc cgtctttcac tgcaaagact gttgttccac tttcaatact tgttccttcc
       61 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
      121 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      181 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      241 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      301 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      361 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      421 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      481 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      541 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      601 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      661 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      721 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      781 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      841 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      901 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      961 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
     1021 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1081 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1141 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1201 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1261 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1321 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1381 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1441 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1501 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1561 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1621 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1681 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1741 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1801 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1861 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1921 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1981 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     2041 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2101 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2161 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2221 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2281 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2341 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2401 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2461 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2521 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2581 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2641 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2701 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2761 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2821 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2881 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2941 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     3001 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3061 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3121 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3181 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3241 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3301 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3361 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3421 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3481 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3541 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3601 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3661 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3721 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3781 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3841 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3901 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3961 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     4021 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4081 catttttaac atattccagt attcctgaat aattcatagc tttaattctt tggcacattt
     4141 tattgaaata tgtatcacta atatccctat caactgattt tgactaaaaa gttacttcaa
     4201 acattcactg ttcaaaaata ttgaggaata aattttgggt gtaaggcatt ttgagcatac
     4261 ttctccctgg ataacttccc agtaaaaaaa tcgttagatt gttggattag atccattgac
     4321 tggctcgcct caggcgagca aagaccctgt agaattcatt ctgatacaca tgataactag
     4381 ataatttgag atagactcgt ctacccgttt ggactaattt cccagcaact ttcagaaact
     4441 tcaatcgaat agaatgaatg gtcattccct tttggacttc ttcaaagcca atcgttctta
     4501 agaagttgac taagttgtaa gctatcaagc tgagcatcat tcggacatga ttctccaaaa
     4561 agcgaggact gtctgttttg tcaaagtaaa agccagcttt cgcttcttta atgaagttct
     4621 ccattgtgcc acgtttggca tagatagaaa agatggtatc aggagaaaca ttttctgata
     4681 gattcgtcac gataaattca tgtcgaaaga gtagttcgcc cgcttcacgt gttgagcgta
     4741 tacacacgcg acgactttgt gaccaggatt gtgcttgata agtggtcgag aagtactgaa
     4801 cttctcgttc ttcccacttt tgattatcgc cataaagtac tgatttctca gctatttgac
     4861 ctagtctacg attattcttc agtcgaataa cataatgact cttttttgat tcacacgaat
     4921 catacacacc aggtgtagcg aacccgctgt ctccacgaac caagatgtca gtgtttggta
     4981 gagagtgatt atagtgctct aataaaggtg tgagaaactc ctttacgcct tttgatgtat
     5041 attgatttcc tgaacgtagt tcagctttta agaagtcacc agtcaatccg tcaaaagcta
     5101 ccaatggatg gtaaccatag gtttggtagt gtgtattata attcgtttgt tcttggtgac
     5161 caaatgtatc tgaatgggtc gaatctaaat caatgattaa ttccgtatca ttacggatga
     5221 ggcgtgcttt atcgataagt tcttggttca aagcttgaag ttcatggata ttctcctcag
     5281 atagtcgatc taaaaatcgg gaaagtgaag attgagaagc gagttctttc ctatctaaaa
     5341 cagctttaaa cacaggatct tgtctcagga gattagctgc agaatcagct gagtaaccag
     5401 caattaattg cataatgaac tgctcaagta tggataagtt gtcatgagta aaatacgctc
     5461 gttcgtcttc aatgtgaatg tgttgcttag ccagttcaga aaaaccaaag atgttcatca
     5521 gctctttcac taggacgaga cccgaatcac tcgataattg accacctgta tgagaaatag
     5581 tgatatttga attgaatttt acttggtttt tgtgtaagct agtcatgaaa agaactcctt
     5641 tcttttggtt ggtttagtca ctttaaccat agcagaaagg ggttcttttt tcatcactta
     5701 acgggtgaag atgaaaaagt aattgtaagc tgccgtgagg cagtttcaca tggttttaat
     5761 taaaagtatg aattattcag ggtattttat tttcataaag aaacagatat atttctggat
     5821 cgtaattttg tgataacaga ttatctattt tgatttgctc gatagtttta cttagatttt
     5881 ctgtatattc aattaacggt tcatggaata gatcttctat ttttccagta aaaaaataat
     5941 gaactaaaat cagaatatct cgaatgtctc ctaaagaata caaagtcaaa ttttgcaatg
     6001 aattatagag tcgttctcta tcagccattg caacattcaa attgttcatt tttagtttaa
     6061 aaaaaacttt atcaatatta tttgctctaa atggaccaaa taagtaatat ctggttttaa
     6121 acatgtatag aagaaacatc tcattaaaat caccagtaaa gaaatggaaa tctttagttt
     6181 ttttaatatt atcagttagt aactttttat aatcataaaa aaaataagta gttctatctg
     6241 agcgatactc ttttataata ctgaattcgg aattaaaaac cacgataggt aactttaaac
     6301 aaacatgaag agactttaat aagacttctt tatctgaaaa cacttttgtt tctctctttc
     6361 ctttctacat cattaaatag tattttatac gttatctaaa atactattcc tctgtcaaaa
     6421 taagctaact tacttcatta taaaatatcc acttatcgct ttcatgtata ttccaccgta
     6481 aaaagtacat tttatcaccg agaactcatc atttttcatc atgatgaata ctatttacat
     6541 atatctagtt caaagacaat aattattatg atccgttatt atctaagcac tatacagata
     6601 ataggaattt ttcgtttcta aatattccaa tttgggaatc caataaaaat tttcgttcaa
     6661 atacgtgtct attcgaactc ttttctagtt gttaattatg aagggggaag aaataaaaaa
     6721 tacaatctat acacgaataa gaatattatc caaaaggagg ttttagaaaa gatttattat
     6781 acgtaaaaag ctcaagacat tttcttagcc ataaggacat gtttgatatt taagaagata
     6841 tatgaatttt cttttctaag tataaagata actatccatt atcaactaaa aaaacatttt
     6901 tgaaaataaa catcagcagt cctatcaatg catgtgagct tatagaagtt attcgcagcg
     6961 cagcataatt gcattagctt cttttcgtgt tttttgcctc ttttcccttt aaatcttaat
     7021 ggaggaggtg tgcaatatgt cagataacga cgaacgcgta aatgcccagt tgattcgatt
     7081 ctttgaaaag gtcattttga acaccgctaa tacttattat aaaaaacaag aagaaattca
     7141 aaaacatgaa caacttgatc aactcccacc atatttgttt actaaagata ctataaaatt
     7201 taaacaaccg attaatgttt taaatgtgac tctccttgtt gaagatataa aattagcaaa
     7261 aatccttcct ttgttgaaag aacctgaaca aatttttctt atcgaaaaat ttatctttga
     7321 taaaactgat aaagaaattg gaaaggttct ggggattaca agacagggtg cgacaaattt
     7381 aaaacatcga ctttacaaaa aaattcaaaa aatgctggtt taatatctgc ataataacta
     7441 attttgtatg cttctttgct cgttctcctc cttcccaaag aaatagatta taagtccatg
     7501 ggaagaaggt agatttatga attctttaaa agaagatttc attttagcaa aggctggaaa
     7561 tgaagaagct gttgaggcaa ttctcaaaag atttagctct ttgattcata agcaatcctg
     7621 gagaactgga aaatatgatc aagattgtta tcaagaatgt atgcttgcaa tatatctagc
     7681 tatctcgaaa ttcgaaatta aagaataact caactaaggg agtctgtgac ataagtaaaa
     7741 agatagtttc aaatttcgaa caataaattt gaaactatct tctttataat tataaagtat
     7801 cgattttaca gcgttctata atgattcata gaatctaaaa cgaatgattt taattatcaa
     7861 cgttttttaa ttcgttttta gcttaaaaat aacttttgtc acagtctcac tcctaaaatt
     7921 actttattta cgtatgaagt gggcaggagg tcgaatccag aactgggcta tggtacttca
     7981 acgaggactt ctcctctaga attgaaaagc atgcgattta ccttccgtaa cgacggtaga
     8041 tttattcaac tatgtgtcca atcaaaattt gtctgatttc aaaaatagtc aagagaattt
     8101 tggttgttaa aaactcttat ctatcaactt ccacagttta gttgacaaac cctgatacta
     8161 agttgggcta tgatacactt ttcttgacta tcagttacgt taccggaagg aatgaactct
     8221 attgagaaaa acatatgatc gtaaatttaa actaaagatt tcacaggata tccttgagaa
     8281 aaaagtaact accaagaaaa ttgctgaaga atacaatatc tctcgtccaa caatttcccg
     8341 atgggtttca gaatatcgtc gatacgggaa aaatgctttt gctggacaag gaaaaagatt
     8401 acctgataaa gcagatttct acattcttga acaggaaaat aaacgactaa aagaggaaga
     8461 cgagtgttct acgaacacaa agatcgatac ggatctccag ggatcactca aaaactttac
     8521 gatgaaggaa tcgaaatcaa taaacgtgtt gtagctgttc ttatgcgtga aatgaattta
     8581 tgcacaagag gatttcatcg acgcaaatct tctcatggta gagaaaaaac aatcaaagaa
     8641 atggtaaaaa aatgttgaat cgataatttg aacagaacca aattgatgct gtttgggtga
     8701 tggatattac ttacattcca tgtaatgacg gtcgcctcta tttgtccacc tatattgact
     8761 tagcaactcg tattctacgt tactatatgg tagattcaca catgaaaaaa gagattgtcg
     8821 tccgtccatt acaaatttat taaggagaat tgcctacggt aattcattcc gatagaggta
     8881 gccagcatcg gtcttttatt tatcaagagc tgttgaacga ccaccacatc acacattcag
     8941 tgagccaaac tgggactcct gttgacaatg cagtaattga agcgtttcat cgatcaatca
     9001 aatgagaatt aatcgactcc aacaaatata aaagtaaaat agagatgaag gtgttaatcc
     9061 aagattattt agaagactac tacccaaaca aaagaatcca tacaaaattt atgatgactc
     9121 cttgacaatt tgaagcgaag aaaataaggg atctataata tctagtgttg gtgacgcctt
     9181 ctgttgccaa tactttttct tttttctaat aaacgcaaac agacacctta aaatccttta
     9241 gaataaagtc gacgaaaacc attcaaagga gtgtttcaag atgtcctatt cagagtttac
     9301 caaagagtta ctagatattc tagacctaaa tcttatcttt catgaagatg cctttcgcaa
     9361 agagcgaatc aatgacgaaa catgttttgt ttttgatggc acattgacct atcaaccgga
     9421 ggaatgcttt catcgccact atcaaaatga acaaacgatc attaaatagg gctggaaaaa
     9481 agtatccatc ttattgaatg atgtcagtaa ctacaagacc attctgcgga ttaacaaaca
     9541 gcgcttcaaa tgtaaacact gtggaaagac ttttttagca gaagattcag ttagtgatcg
     9601 tcgctgctcc attgctcgca gagtcaaaca agccattctt gagctattaa gcgaacctct
     9661 ttctatgtct ttgatcgcac gtatgaagca catttctccg accactgtca ttcgaatact
     9721 tcgcagcctt cggcctaaaa ccatttcttt gagccagctg ttaccagaag tggtgtgttt
     9781 cgatgaattc aaatcagtga aaaatgtctc gggagccatg agctttgtca tgatggacgg
     9841 caagacccat caactgattg atattgtgga aaatcggcaa ctcaatcctt tacgcgacta
     9901 tttcttgcgc taccctataa aagtccgtga acaagtgcgt ctagtggttt cagatttcta
     9961 tacaccctat cgcacattgg tgaaagagtg ttttccgaat gcccgaatcg tcgccgatcg
    10021 ctttcatatt agccaacaca ttggtcgggc ttttaccaac caccgaattc aagtaatgaa
    10081 gacctttaaa aaaggggatc gtcggtcgaa gcacttaaag aaatactgga aactacttca
    10141 aaagaatgcg tgggaattga aaggtcagca tcgctactgg cgtccgtcat ttcgagatca
    10201 tctgacagaa gcagagatag tcgatcggct attatcttat gatgattcct taaagcgagg
    10261 ctacgaagtc taccaggatt ttctttccgt tatcagaaga caagatgttc ctgaattcgt
    10321 cgcgctccta aaagaagact acaaggagtt gccagagcac taccaaccag tgttcacgac
    10381 cttcaagaaa taccaaacag aaatcaaacg agcgttgcgc gttccctatt ccaacggccc
    10441 tatagaatgt ttgaataacc atatcaaagt actaaaacga attgcctatg gctatagaaa
    10501 ctttcaaaac taccgagaac gaatcttttt atatcgagga aaatatttta agaaaactaa
    10561 gaatactacc caactgacta aagccagaac aacaacacgg ctagacaaga tagctgtcta
    10621 gccgtgtgag tatctcgatt attctattga atttcttcac caacactcat tgacgaagag
    10681 ccaaaataag taatctaacc gactgttaac taaaccattg caggtcccgt taaagatact
    10741 tgtgcctgtt gtcaccgctt ctttttcttg tccacaagcg cttaacacac ttaataaagc
    10801 ccctgctatt attaataata atatcttttt cttattaaaa acctcctcat ctatttccag
    10861 attagtaaat gtagtaatct gtgctttctt ttttctcaat actaataact aacttatggg
    10921 gtaaacaaat actcgtttga ccgggttttg agatccatcc agttctaacc gcgatttgat
    10981 caggactatt atcttcttta actcgaattc ttccatcttt aatctcaaca atattatatt
    11041 gtcccttcgc aggatgataa ttcacgagtt tatgattgat cttatccaaa tcgaagcgat
    11101 ccatttcctt gccatcaatt cgaacgatgg catatttgat agcatcttca gttgtttcat
    11161 tctccttttc tatagagaat acaaataagg gaataaaaga ggtaataatc aaaatgccaa
    11221 taattatgac atcgcctatc ttgacaccag cttttcttaa aaatttcatt aacgatatct
    11281 ggctaaacat attagacttt ttccatggaa atggtgaaat ttttcggaaa ttatctgcat
    11341 taagagaatc agttaaacaa ccctcaagtt gttccttaat acattgttga tccatcttca
    11401 taccaataaa aactagttta ttaatgcgtt caccaaacaa cggatgccag gcttccttca
    11461 attcgggatt tttttgtata atcatttgac actcaatttt aggtaaacta gctacccaat
    11521 aatttaatga ttcaatactt ttatagctac ccgatgtttc aaagatcgtc gaaaaatcac
    11581 tatgttgggc aaaccaaaga aacccttttg ctcttgtaat attgccagga aaatttttat
    11641 ccgtaagatg ggcaaatttt tgtgcgtcaa ggagtaaccg atttcgatag ataaaacttg
    11701 agataccata ttcttctgtt tcaggaatat gattttgata gccaagctct aactctttga
    11761 accagcccac tgaataggaa gtctcatcta tattaaaaag atttgtattt agaattttcg
    11821 ataagtctac ttcaccttta attgtcctaa ttattttggc attggactgt aacttagcaa
    11881 ttagaccgtt aattttgtaa atcgtcttgg ttgacactaa gtcactatta tttaaaagta
    11941 atatgttaca acactcgaat tgatcaatta acaagccacg aatatcctgt tcttcttcaa
    12001 ctacattacc ttcagctttt ctttcctgaa tcttttcacc cgtttcgaaa ttatcccaaa
    12061 aacgttttac atccactact ataataatgg caccaatctc taatcgttgg gtcaaatcaa
    12121 tgtctaaagg gtttttagct aatataattg cttgaataat tggaattggt ttgctgattc
    12181 ctgaagcttc aataacaatt tgattcaagt cagaaaattg cactaattga tctagttcaa
    12241 caatcaaatc ttcgcgtaat gtacaacaaa tgcatccatt cggcatcgaa acaagttttt
    12301 ctccagttct tttaaaacct ttcttgtcga ctaatacccc atcaacattt acttccccta
    12361 tgtcatttac aatgacagca atttcctttc cgtgatcacc gtacagaata tgatttagaa
    12421 gtatcgtttt tcctgaacca agatagccag ttaagattgt aataggtatt tttttcatag
    12481 ggaacctctt tctatacctt gaatttacac tttaagtgca acacataaaa atgagtcata
    12541 atcgatatcc aactagtata agtttgtcga gaacactcct agaaggaaaa taattatgag
    12601 ccagtatcgt catcttacta tactcgaacg agaaagaatc tttctgcttc acgaagaagg
    12661 attttctatt agtataattg gcaacgacat tcagcatagc ccgtttacta ttttacatga
    12721 actgagaaga aacaagaaaa aaactattca ccttccaaag cggaaaaaaa ttatgcttat
    12781 cgaagaaaaa aatgcggacg ttatcacatt ctaaatgatc cgtgagtttg gtcaattgtt
    12841 cgtcatttat ttgtcgattt tcagtggtcg ccagaggaaa tctcgaatcg tttgaagcat
    12901 gaacatatgg acttttcaat tagttttatc acgatctaac gtgcaatttg caatgatctt
    12961 ttcgatacag aacccctctc acacggcaat aaaggcctga tccgttcatt gcaccatcga
    13021 ggaaaaacaa gacatacaaa aaatcatgtc gagtctcgtg gaaagatttg ccttactcat
    13081 tcgatccatg gccgtccaaa atccgcagat gatagaagtg attttggtca ttggaaagcc
    13141 gatattgtag ctggcaaaac tggtggtact tgtttagtga ctttgacaga cagaaaatca
    13201 tgcttccttt tagcaggaaa gaaggtcccc agaaagaaag ccgcttatgt gagcgagaaa
    13261 atgattgaac ttttaagcag tattccaaat gaggcggtca aaacgatcac tccagataga
    13321 ggaaaagaat tctccaatca tttcgcagtt acagaagcat tgaataatat gcccttttat
    13381 tttccagatc ctcatgccct tggcaacaat gaacaaatta aaatacgaat agactcattc
    13441 gagaatactt gccaaaatcg aaagagatag ctacggtaga taactcaacg ataaatcaga
    13501 tgattgaaaa actgaataac agacctagaa agtgtttaga ttggagaaca ccttatgaag
    13561 tcttctttga taaagtgttg cgcttgattt gacaattcaa gacataataa aaagcagatc
    13621 aaatccaaat aagggaaaaa tgatctactc tggtattatc aattaattgg ccaagctatt
    13681 atgccgtttt gctaaacgtc tacttcttcc agtattgacc ttgataaaac aacaatcagg
    13741 atcccgtttt aatactctat gaactgtgtc aatactaaca tgtaaagttg cagcaatatc
    13801 agctaatgta ctcccattta atctcatttg ctttgcaaat cgataacgcc gataagcatc
    13861 aatattcttg gaatccatag acaataatac ttttcttacc atgtatttcc tccaaaaatt
    13921 gaattttaat gagccatcat ttcttgagca atttcatgtt tagacaatga agctggatag
    13981 aaagtaggcc aattatgcaa ttcattatag agtttttctt gactttctcc accaaagaaa
    14041 atatggaaat gctctgcctt acttggtgca attccatgat cactaaattg aatatattta
    14101 aaacgaccag cacctgcatc atcagtttca aaattaaaac gaacaccacg gtttcctttt
    14161 tcataattca aaattttgta tccaacatat ttgtatgtgt attgatgatg ttcaccgttg
    14221 actacaaaat caatggtgtt gtctttaatg ttgatagtat caatatctgt cttatagcca
    14281 gtagtataat aatctttgta ctcggcagct gtcatgtctt tattgatttt tgctttgtaa
    14341 tcgaaaactt catccaaaat tccatctttt aacaacggat aaacagattg ccattcgcct
    14401 gtataatcac tcaattcgcg atccttcaca tcggcatctt taaagtaccc attagcaact
    14461 gtcttttcat ccttcgcttc tttttctgga actacctctt caccagcaac catagttgtt
    14521 ttttctaacg cttttagatt gtcttccatt actgaaacat aatcttcacc attatccatt
    14581 tgttcttttg taagactttc aagaggattc agtacttcca attttatccc agcttcgttg
    14641 gccaaagttt ttgcaatttt atcattagca ttcttttcaa agtaaatata attgatctta
    14701 ttttttttaa catactcttt taattcagct aatcgaccag aagatggctc ttcttcagga
    14761 cttagtccag caataggaac ttgtttcaat ccataatcca aagctaaata tccaaaggct
    14821 gcgtgttgcg tcacaaaact tttttgtttc gcttctttaa gactagtggt atagtcagca
    14881 tccaaccgtt tcagtttagt caaatacttt tcagcatttg tctcaaatac ttttgctttt
    14941 ttcggataca atttaactaa ctgatccttg atatttgaaa cttccttaat tgccattttg
    15001 ggtgaaaccc acgtatgagg atctagttca tgatggtgat cttcttctcc gtgatcatga
    15061 tcttcttctt cactacctgg caataaaatc atgtcttttg ttccttctac tacattaggc
    15121 ccagctttct tccaactttc tttagctttt ggtacccatg attccatgtt ttcgttatga
    15181 tatacaaaaa catcagcatc atgagctttt gccatatcct tagctgaggg ctcatagtca
    15241 tgaggttctg atcccgctgg aaccattaaa tccacgttcg cttcatcgcc gacgatgttt
    15301 ttggtgaaat catacattgg atagaatgtt gttacaattt ctaattttcc atctttatca
    15361 ttcgatactt ttgcatcatt agtgctggag caagctccca ataatcctag agctgctatc
    15421 ccaataagtc ctacactgat tttcttcatt ctttttcctt ccttaattat gctaatttct
    15481 tcattttatt tcgtttatgt tctttgataa tttttaatgc cctttttcta gttttaatat
    15541 tcgggctttt aagtcgtcga tatgcactag atatatccgt tttctccatt agaaattacc
    15601 cccaatcact acttatcatt atttgctttc cgccagtaat ttatcaaaac tctgtttgat
    15661 cctttcttca tccaacattt ttccgattag aataatagtg gtttggtctt tttgtcgagt
    15721 ggtgtattga aaattaacct gttcgtttac ctcttgcatg gcaactataa aatcctgctc
    15781 ttgtaaagca atcaatcctt taaaacgata caggctccct tggttggtta aaatcagcca
    15841 gtcaatccat tggagtaaaa aatctttttt tatgtcttga tctgaagtta agagaattga
    15901 tttaaactca tgtacttgat ggtgttgatg atagtatttg ccattatagt gattttctga
    15961 tgaatcactt tcaaaaacta agggatgatt aaattttttc aaattataaa aatccttttt
    16021 ttgaatcgtt tcactatgtg tgaacattcg aatatcggat aaagggttaa tacttttgat
    16081 ttctctctgt aattttttta gtgcagataa attcaagttt tgttttctag acacaaaaat
    16141 gcgatctgcc atgacaagtt gcttaagggc ttgtggttct ctttcaataa gttcaaaact
    16201 gtcactatca ataacagtca ataaactatc gatatatact cttcctctta gttgaggcgc
    16261 tgttaaaagt gtttgaatga ttggttgggg atctgctata cctgtagttt caatgatgat
    16321 ttgtgaaatt ggttgttgat gttcttctat tgtttccagt aaagaaatca atattgctaa
    16381 taaatcactg cgaagactgc aacacataca tccattattt agttgtaaca cccgttcctc
    16441 gctatgaact aataatttgt gatcaatccc aacttcacca aactcatttt caattataat
    16501 aatttcttcc ctggggtagg gtgagacttg caaggcttga ttgattagcg ttgtttttcc
    16561 agcccctaaa aacccagaaa cgattgtaac tggtatgccc attttgtcac ctttttacca
    16621 cttagctatt tcacttcttt aaaaattgcc cgtctgcgca attttggcga atactttttt
    16681 aattctaacc gttcagggtt attccgttta tttttgctgg tgagatacag acgttctcca
    16741 gtttcgacac attccaaaat aatattttga cgcataaatc ttcctccttc aatacttatc
    16801 gatcttcaag atatgcttga atttgttgtg catcttcaaa agttaactcg ccagattcca
    16861 attgtgaaac taaattttct ttcatatcaa caggtatctc ccaataacca tcgatacatt
    16921 gaaataactc ctcgtcatac tcttcaaaaa ttggatagat tcttaaaaaa tcatcaaatg
    16981 ataagccttg gtcctcatag taatctttga ctaatccatt ttcaattgcc tgttgggtcg
    17041 gtaaacccgt ttcagtaata attcctctct ctaccatcga acgataaaaa gtgcatttat
    17101 ctagcgattg ctgggtcgtt tcaagataat actttaatcc ttcttcaact aaaggtgggt
    17161 aaataatttc cattttgatt ccctcctaaa agttatatat taaactattt tgaagctcct
    17221 ttaattactt tctttccatt atagtaccct tttaaagata catgatggct acgtctataa
    17281 tcaccattcg cttcgtcaaa tgaaatttct ggttttacta cagtttgatg agttcttctt
    17341 aaccgtttct tcgccttaga tgtttttctt gctggtactg ccatgatatt tcctcctttt
    17401 accaacttgc tttttttact ccaggaatca acccttgatg ggcaagttct ctaaacttaa
    17461 tacgggacat accgaacttt cgcatatacc ctcttggacg accatccgtc tgatcacgaa
    17521 gcctcagacg attcggattt gaatctcttg gcaatttagc gagagcggtg cgatctcctg
    17581 cggcttttaa ttcctgacgt ttatctgcat acttttcaat catcgccatt tgtttctttg
    17641 ctttagcaat tttcgacttt tttgccatat acctttatac tccttttatt ttgatttaga
    17701 cacctcaaat cgtaatcgtt acgttttgac actgatactt taccaacaag agttgctctt
    17761 gtcaacaata aataacatga aataaaactc atatgaatag ataactattt gaaaacgaat
    17821 ttatcggtac atagagataa tcaaatcatt taaaagaata tgcagtttag gctctgaaaa
    17881 ataagaattc acttttatta gtccaatcaa acacaaatac cgttttaagt agcttttcct
    17941 ctacttaaaa cggcaatatg aaagaaacta taacttttta ttcaatcttt tatgtttaac
    18001 tggtttatcg ccaatttttt aaaactttga ttattcctta tattataaga atagacatta
    18061 agtgaactaa ttcaatcata ctgattcttt cgtgtattca aaattagatg ctgtttaata
    18121 aaattattct ttttgaaaaa gaattataac tatatcccaa aaattgtagg ttaatttaaa
    18181 gcctatttca tcatcgtgat tgagcttctt tttcatagac gaatttctca gatagtttag
    18241 ttttctttat gagatttttg tatatttctg accttcgata caactcatta tgagtacctt
    18301 gatcaactag ttttccttga tccatcacta caattttatt taccttttca atagacttca
    18361 agcgatgcga tataattagt actgtcttat cttgtattaa acgatttaaa ctttcctgaa
    18421 tacgtttttc attttccgca tctaaactgg cagtaatttc atctaaaatt aaaattggcg
    18481 catttttcaa aaaagcccgt gctatggata ggcgttgtcg ctctcctcca gaaagtgaac
    18541 ttccgttttc tccgaccaat gtatgataac cgtcaggtag tttttcaata aagtcttcgc
    18601 agttagctaa acgagctgct tttttcactt cctcatctga cgcttgacta tttccaatac
    18661 gtatattttc caaaatactt gtattaaaca aagttacctc ttgaaaaaca atagcgattt
    18721 tgctaaacaa agaagctgga gatacacgtt taatatcata cccatcaatt aaaatacagc
    18781 cttcatcata atcatacagt ctagacacta atttcaagat actagttttc ccggaaccac
    18841 tagcacctac taacgcagtc acttctcctt gtttagccgt aaaagagata tgatctaaaa
    18901 ttggggtatt gttatcatat gagaaagaga catctcgcaa ctcaatgtca aaagatttca
    18961 gaggactatc tgatccctct tggatactgg tttccttcat agctctaatt cgctgtattt
    19021 taggagctaa ataaaatatt tcaagcactg cttctttcat agaatcgaag gaatccttta
    19081 tttttattgc ggctagtaag taaccaacga cgtagagtat agtcacttca cccgttaaca
    19141 gtaagtgaac acctactaga atgactactg ctaaactaac atatgagaaa atagaggata
    19201 aggccatgac tgaaaaagta cttaattcta cctttaaatg aatcctttca ctctcttcca
    19261 tttttttgaa aagtctgtct tgaacttttt tagatagatt aaagctatta atctcttgct
    19321 gcaattctat agtttcttga aattcttccg agttttctct caaagtatcg taatatttag
    19381 tattggcttt cgtttgggat ttctttgata acaagattaa gacaaaacta aataacgttg
    19441 gcaaaataac agctaatccc attttgacat taccaaccaa aagcatcact gaaataaaag
    19501 ggaaaaacag agccataccg ccggctttag gtattgcatg actcatcgca tgctcaatac
    19561 cttcaacgtc agacatgata gtttgagata aatctgataa attatgtttt gaaaaatagg
    19621 ataatggtaa atttgacaaa tcgtctgcaa tttgcactct taaatgcgca ctttctttat
    19681 aagtactatt atataagttt tcatactccc tatctaacaa ccaatacatg aaaagcaaag
    19741 taacaaacga tacggcaaaa taaagccaac ggggctttgt attttctaaa actaattcgt
    19801 ctatcagcat cattataatg aatgctggta ccatattaat gcagtataca aaaaaactag
    19861 aaatagaagc tttagttaaa gcttctgcgc cctgatcact taaagcaaat ttgtttttat
    19921 aaaaactttt cattgtcaag cctccaatca tttgcattct cataattagt gaccaattgt
    19981 ttatacactt gatgtttagc cattaattca ttatgatttc cacgttctac tattttccct
    20041 tctgacaaga caagaatttc atctacagat ttaatgctgg ataatcgatg agctatcata
    20101 ataactgttt tttcttttat cagatgttga aaagcctttt gtagttcata ctcattatct
    20161 ggatcaatag atgcactggc ttcatccata ataacaatct ttgcatcttt taaaattgct
    20221 ctggcaatag ctatacgttg tttttctcct cctgacagat aaactccttt actaccaatt
    20281 aaggtatgct ctctttcggg aaatttttct aaaatcgatt cgcaaccggc taatcttagc
    20341 gcgtcaaata ctttacttgc tggcgcttga ggatttgcta tagaaacgtt atcgtaaata
    20401 ctctgattga atagtttcgt atcttgaaag acaaaagcaa ttgtgttaat aattgtgtct
    20461 tttgaatagt gatttaaagg cttaccacca attttaatct gtcccttatc cacattgtag
    20521 aaacctgaaa ttagtttagc tatcgtactc tttccgcttc ctgattttcc tactaatgca
    20581 taaattcttt tttgttctaa aactaagttg aaattttcta aaacacactc ttctttgtat
    20641 gaaaagctga cattttcaaa tgcaatgtca caatttttaa tctgtgtctc gttcccatat
    20701 tttagttggt cttgcttcat ttctaaataa agggagtcta gtgtttcgac tgcatatctt
    20761 gcttcaaaca agtgcatact tacatacatt attctcatga aagaaacaaa aataattcca
    20821 cttaaaaaaa acaacatcaa caagtcaaca gctaatatct tgggagtggt aagagaagtt
    20881 ataaaaaagg ttataggaac tatcaaaatg caaactatgc caaaaaatag ccattgaaaa
    20941 agaacaaaag gtgttttccc actcaaagaa tacttatatg caaacttagc ataatcgtta
    21001 attgctttat tcaaggcttt aaatgatgtt actttagcac caaatatctt tataacttga
    21061 attccgcgga tatattctac cgtttcagag cttaacacat ctaacgattc ttgatatttt
    21121 tgaataaaat ttgtattctc tgtcattttc tttaacaaga atacaccaat tactaacatg
    21181 gcgattagaa ccaatccaat tttaaagtta atgaaaaagc ctaaggcaac tgataaaaca
    21241 ggtgttacta tggcttgagc actatctgga atcaagtgag caattgccat atgtgtttta
    21301 gccgcgttgt catcaattgt ctttcgaata tatcccgaag aatttaaatc aaaaaaacga
    21361 aaacttgctt ctgttaaacc gctaattccc ttttttctca aattagtctc taagcgaaac
    21421 ccaaggatat gagaaaataa gccagaaaaa atataaaata aagctcctaa agttaaccaa
    21481 gcaacagttt gaaccgcata actcttagct aaatattcat ctcctacaat aattagagac
    21541 tgaagaaatt tgtaaatact gtaatatcca tagactgtta atacgacaga aaaatcagaa
    21601 aataaagtgg ctaaccatcc gtagtatttc attttaggga cataactaaa taattttttg
    21661 tatactttca ttttttcctc ccccgcattc aatttcttct cttattcgtt tacaactgtt
    21721 aatgctttcc gtaatagcgt aaattagaga tgtacaaaca gataaaaggt aaactacgtt
    21781 ctattttttg tattttttta agacttttct tccaatcaat acaccaatca tagataaact
    21841 tgctacaact aacactgaaa tgattcccca tatacctacc gcatagtgga tcattgcatc
    21901 cattgttgca gcagattgtc ctttatctat ccaatcttga cgaaaacgat ctgtaaagaa
    21961 ccatatagga atccactgtc cggcagcact gcctaattgc attagagccc aagacgcaac
    22021 ttgaggaatt gctcgatcat atccaaatac agatagaata atatcagcta agatcgccat
    22081 actaatcgaa ctgataaacc aaggtaagta cgccccgccc attaacgtaa aaaataacaa
    22141 taaaacaatt gtgtaaatag taaaaattcc ttttctaggg tagttatagc taatataaac
    22201 aaatatgatt ccagataata atccaaaaat cccgggggat atgctgtgac caaacgcccc
    22261 accaatacta ctaaccatta ttgaaaaaaa gtaaattact agggaaataa ctgtagctaa
    22321 accaataaaa atataatctt ttgttttcat atatattctc ctcaattcta tttcgttatg
    22381 tcattaaaaa tctgttctat caaagttgaa tcttctactc taagttttat atcttttttt
    22441 attccaccat tttttaaata aataattcta ttgcatgttt tataaagaaa ttccggatca
    22501 tgagtagcta taactactgc acccttttct tttaagtctt taataaggtc agcaatcctt
    22561 tccatattaa tataatccaa cccacttgta ggttcatcaa atagaaataa attagttttt
    22621 gacaatgaag ctatagaaac caataatctt tgtttttctc caccggataa atcaaacggt
    22681 aattgatctt tcattttata aagttccatt ttttttaaaa ttttttcttg ctgatcttta
    22741 ctaactattt cattccccag ggctaactcg ctcctcactg attctgtgaa aaattggtaa
    22801 tccatttctt gcattactaa aaacggcgat gacaaatttt ttttattttc gattatcttt
    22861 cctttggtag ggcgaataat cttcatgagt attcttagta aggttgtttt ccccacaccg
    22921 tttttcccta ccaaaccaat aacatctcca actttgacat caaaatttat gtcttttaga
    22981 atattttcat aagtaatctc ttcaactttt aatacatctg cacttacctt ttcgatatag
    23041 ggaacttcaa tcgaactatt aaaaatgtca aatttcctta atgcgttatt gttttcagtt
    23101 tttaacaact gaatagttgt agtttttaca gttctatttt taacaaatag aacttgatca
    23161 attaattctt tcaaatagta aaaacgatgt tcagctataa caatagtaaa tcctttattt
    23221 tttaaatcac aaagtaagtc agcaagtttc ttagtcgctt tgaagtccaa atttgaagac
    23281 ggttcatcca atataatta
//
LOCUS       DAPBBV010000047        21596 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.047, whole genome shotgun sequence.
ACCESSION   DAPBBV010000047 DAPBBV010000000
VERSION     DAPBBV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.047"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            144..542
                     /locus_tag="RD486_002212"
     CDS             144..542
                     /locus_tag="RD486_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDT7663930.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="RD486_002213"
     CDS             526..1221
                     /locus_tag="RD486_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDT7663931.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1815..2702)
                     /locus_tag="RD486_002214"
     CDS             complement(1815..2702)
                     /locus_tag="RD486_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDT7663932.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2887..3726
                     /locus_tag="RD486_002215"
     CDS             2887..3726
                     /locus_tag="RD486_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7663933.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3922..4896
                     /gene="sgrA"
                     /locus_tag="RD486_002216"
     CDS             3922..4896
                     /gene="sgrA"
                     /locus_tag="RD486_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HDT7663934.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5194..5550
                     /locus_tag="RD486_002217"
     CDS             5194..5550
                     /locus_tag="RD486_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663935.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5553..6710
                     /locus_tag="RD486_002218"
     CDS             5553..6710
                     /locus_tag="RD486_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663936.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6736..7176)
                     /locus_tag="RD486_002219"
     CDS             complement(6736..7176)
                     /locus_tag="RD486_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDT7663937.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7336..7842
                     /locus_tag="RD486_002220"
     CDS             7336..7842
                     /locus_tag="RD486_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7663938.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8010..9923
                     /locus_tag="RD486_002221"
     CDS             8010..9923
                     /locus_tag="RD486_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HDT7663939.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9928..10929
                     /locus_tag="RD486_002222"
     CDS             9928..10929
                     /locus_tag="RD486_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7663940.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11131..11337)
                     /locus_tag="RD486_002223"
     CDS             complement(11131..11337)
                     /locus_tag="RD486_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HDT7663941.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11983..12831)
                     /locus_tag="RD486_002224"
     CDS             complement(11983..12831)
                     /locus_tag="RD486_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7663942.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12830..13897
                     /gene="gnd"
                     /locus_tag="RD486_002225"
     CDS             12830..13897
                     /gene="gnd"
                     /locus_tag="RD486_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HDT7663943.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13899..14900
                     /locus_tag="RD486_002226"
     CDS             13899..14900
                     /locus_tag="RD486_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDT7663944.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14897..15181
                     /locus_tag="RD486_002227"
     CDS             14897..15181
                     /locus_tag="RD486_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDT7663945.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15214..16011
                     /locus_tag="RD486_002228"
     CDS             15214..16011
                     /locus_tag="RD486_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7663946.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16025..16858
                     /locus_tag="RD486_002229"
     CDS             16025..16858
                     /locus_tag="RD486_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7663947.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16876..17733
                     /locus_tag="RD486_002230"
     CDS             16876..17733
                     /locus_tag="RD486_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7663948.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17755..18264
                     /locus_tag="RD486_002231"
     CDS             17755..18264
                     /locus_tag="RD486_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7663949.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18301..18702
                     /locus_tag="RD486_002232"
     CDS             18301..18702
                     /locus_tag="RD486_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663950.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18814..19167
                     /locus_tag="RD486_002233"
     CDS             18814..19167
                     /locus_tag="RD486_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663951.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19201..19644
                     /locus_tag="RD486_002234"
     CDS             19201..19644
                     /locus_tag="RD486_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7663952.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19661..20746
                     /gene="uxuA"
                     /locus_tag="RD486_002235"
     CDS             19661..20746
                     /gene="uxuA"
                     /locus_tag="RD486_002235"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7663953.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20739..21452
                     /locus_tag="RD486_002236"
     CDS             20739..21452
                     /locus_tag="RD486_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7663954.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7443 a         3314 c         4494 g         6345 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 taactattac ttatttctca tttaaacgat gtattcccta acctctaata catccttgta
     1381 actctgaagt tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata
     1441 aaaatatctt tcgtgtttct ctagtataac agaataagaa gaacaagtcc agaagggata
     1501 tttttagtct tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg
     1561 aagcgatacg gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg
     1621 attcatgtga tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc
     1681 agtgatttgt tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt
     1741 gcctcaaaaa taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat
     1801 tgggtcaaat ttgtttattt gaatatattt tttacataag gatctttaat agttacattg
     1861 tcttttttca tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct
     1921 tcggtagcaa ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt
     1981 ttttttacca tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga
     2041 atgatatcag aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga
     2101 atctctggat tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt
     2161 tttccataag cttgaacaag cttggagaaa ttttctcctt catttgcttc tttttttgct
     2221 ttatctgctt cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat
     2281 tctttccaag cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat
     2341 tggaaagcca gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct
     2401 tttaattgtt ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt
     2461 acttcctttg aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt
     2521 ttttttaata gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact
     2581 gtaagtgttc cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat
     2641 agtaaaattg cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc
     2701 atcctttcct tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg
     2761 taaggttgct gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat
     2821 ttacatagtt ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga
     2881 tgaaagatga tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt
     2941 gttttaggaa ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg
     3001 attggagcaa ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt
     3061 gctagtaagg tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac
     3121 tgggggtatt tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt
     3181 ccattatatt tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg
     3241 ataacgagtt ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc
     3301 ttttttcagc atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca
     3361 ttatttgctc ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc
     3421 tttttagcag gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct
     3481 attggtgctc atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc
     3541 ggaacgcaag aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact
     3601 gggggaaact ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt
     3661 gttggtttgt tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat
     3721 caataaaaga tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga
     3781 ttaaacgaaa aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca
     3841 actgactgtc gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta
     3901 attatatgga gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg
     3961 ctgagtataa ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag
     4021 aatctttcat ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt
     4081 actattccag tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca
     4141 tatggttggg atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac
     4201 gtacaatgga ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat
     4261 gagatcaaga gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc
     4321 acggagaatt tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc
     4381 acaagtagtg aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc
     4441 agtgaaagta gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa
     4501 agtagcacag gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc
     4561 acaggaagca tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga
     4621 aaagtaaata atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat
     4681 gcagggagca acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat
     4741 catcaagaaa aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt
     4801 agaaccttga acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca
     4861 agctattttc gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa
     4921 ttgaataaaa cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc
     4981 gaagttgtag ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata
     5041 acaggaacac aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta
     5101 gtatctctga aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata
     5161 agtctaaata atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat
     5221 gaaaggcaag tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg
     5281 gtgaaggata tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa
     5341 caagcagaat cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac
     5401 aagatgataa aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt
     5461 ttagagggaa cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc
     5521 ttagaaaatc ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag
     5581 aacttaatac tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga
     5641 tagaaggaga agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg
     5701 acgaaaatca ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat
     5761 ttgcgaaaca tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa
     5821 gaatttcgtt gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga
     5881 acaaatttgt gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt
     5941 tttttgaagc aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt
     6001 attttatgtt tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata
     6061 aagtacaaga aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact
     6121 tcaagatttg ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc
     6181 atttgtattc aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag
     6241 aagacagaga ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta
     6301 gtggggtagc tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga
     6361 tttttcaata ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat
     6421 tctatattca atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat
     6481 ctatgactga acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca
     6541 ttagcgatta tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact
     6601 ggaatggaca acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca
     6661 ggaatgagaa aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga
     6721 ttgtttatgc caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg
     6781 accagaaagc aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct
     6841 gattttatct tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt
     6901 tttcaataaa gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc
     6961 tattctgtga acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc
     7021 gttgtttgtc aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa
     7081 gttctgttcg ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga
     7141 cgagcagcca gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt
     7201 tatgaaataa taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa
     7261 aatgttgtca cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag
     7321 aaagaaggca caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa
     7381 ggggtatgtt ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat
     7441 aaaagaatca aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat
     7501 gctcaattag tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag
     7561 cacagttatt ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt
     7621 ttattaactg aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt
     7681 atagatacga ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga
     7741 gcaacgacaa cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag
     7801 aaaatttggg ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa
     7861 aaaagcagaa tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat
     7921 cctgttctat ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac
     7981 atataattct cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa
     8041 agggagcgtt ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg
     8101 gagagagcat ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg
     8161 ctggaaatga aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg
     8221 agacatctgt tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag
     8281 aagaagcaac agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca
     8341 aagagaatgg gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat
     8401 atttgaatta cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca
     8461 agtcaaaatt aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata
     8521 aagagattat caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa
     8581 acagtgtgtt gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca
     8641 caggcttcta tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca
     8701 aaatgatgga tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc
     8761 atggcggatt tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt
     8821 ataaggccgg gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg
     8881 attatgtgac ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag
     8941 ttcgagagcg gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga
     9001 tgatgtctgt attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg
     9061 gatttgcatc aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac
     9121 taccggatgc cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat
     9181 ttatgggcct tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg
     9241 ctctacctac gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag
     9301 atgatgtagt acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag
     9361 atcttttatt agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct
     9421 acacgaaaca tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt
     9481 atgtggatga aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag
     9541 cttatggaga aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg
     9601 ttgaaggacc gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca
     9661 aaaaaatccc agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg
     9721 gaaagaatga acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag
     9781 tgaaagtaca aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga
     9841 aacattcgct tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga
     9901 tttggcgaag aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta
     9961 ccagttatca tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag
    10021 ccgattagct tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc
    10081 cgaccagatg atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat
    10141 ccttcaaagt acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa
    10201 ttaccgattc ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt
    10261 cgtgattatt tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat
    10321 gaacgatcac cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa
    10381 gcagctaaaa aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat
    10441 tcggcaggtg cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa
    10501 aaagctgatc atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg
    10561 tctggtctgt tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt
    10621 tatgaaaaat gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc
    10681 aaaagtttag ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat
    10741 ggaaatacaa atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg
    10801 ggggtgaaag tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat
    10861 cagtttgatt tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc
    10921 aaggagtaaa gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca
    10981 aggagcaatt tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag
    11041 gagttagaga tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg
    11101 tcacgatctc ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa
    11161 agcaacaaat ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa
    11221 gaatgctggt tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat
    11281 agcaaataaa atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag
    11341 cagcacctcc ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag
    11401 tttgttagga tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat
    11461 aagcaattaa tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca
    11521 ataatagaaa atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc
    11581 caaaaattcg atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa
    11641 taaaattaca aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt
    11701 aattcaccaa aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag
    11761 aaaagataaa ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg
    11821 aataatacca atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta
    11881 ttgatgttct gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg
    11941 ctttttttgt tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga
    12001 aatagtatgt cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa
    12061 aatcacatat agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga
    12121 tcggaattct gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga
    12181 agaattagct tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc
    12241 aatatggatt gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc
    12301 cgtcaataaa gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat
    12361 aggggaacgc aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc
    12421 gaaaaaatag acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg
    12481 ttgtaacaac ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc
    12541 catagtgagc tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc
    12601 attttcttgg atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt
    12661 tgtaaattga aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg
    12721 actatgactt actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg
    12781 gctgaagtcg ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc
    12841 tcattttcat aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag
    12901 agtaggaaaa aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt
    12961 gtataatgag ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg
    13021 aaaaatggga ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact
    13081 cgacatttca agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga
    13141 gatctctgaa tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc
    13201 tggagagata accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat
    13261 tattattgaa ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca
    13321 gaaaaatgaa atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca
    13381 tcaagcctgc ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt
    13441 caaagatgta gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt
    13501 cttgaaaatg atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt
    13561 ccaacttgta caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa
    13621 tcatggttcg gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca
    13681 tcccaattta agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt
    13741 tgaaacagcg ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag
    13801 gaatctttca caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg
    13861 gtttggcgga catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa
    13921 tcgttaattc cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag
    13981 ttggagacgt tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt
    14041 tacttaaagg attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt
    14101 ttgaaaacaa agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg
    14161 atttaaaagc agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac
    14221 gaaatgctgt agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac
    14281 aagcacaagc aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga
    14341 cgctgtttaa caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg
    14401 aaattttgcg taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt
    14461 tatacatcga aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag
    14521 atatcatttg tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag
    14581 aagtcgatca gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg
    14641 atgaagaagc gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg
    14701 ttttagaaga agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga
    14761 ttacgccaca tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg
    14821 tcagagatgt cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga
    14881 gcaactatat aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc
    14941 tcaattttat ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata
    15001 cggcgcgaaa agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa
    15061 attagtattt ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg
    15121 tagttatgct gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta
    15181 gttggcgttg gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga
    15241 atcgatttcg gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct
    15301 gtcatgtata aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct
    15361 gcttttttta taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc
    15421 gggttagcag atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt
    15481 ttgcaagatg aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag
    15541 attttgaatc attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag
    15601 ttcaaacagc tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat
    15661 aaatacgcaa gaaatgtggc agcacatgct atgcatgacg ctatcagtaa atatattccg
    15721 gaaagccatc gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca
    15781 ctagaaggtc gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg
    15841 ccggtttctc tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg
    15901 gctgaattta ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa
    15961 tcactgatac agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg
    16021 acacatggaa acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt
    16081 tatgtcccgc tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac
    16141 tggattagtc gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc
    16201 tttgcaaatg atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc
    16261 tattgcagca gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc
    16321 gattgccgtt gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt
    16381 catcaatact tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc
    16441 tatggcccga tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct
    16501 tgttttcatt gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga
    16561 gggaacagtc gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat
    16621 cgcgacaact gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta
    16681 ttttatgagt gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg
    16741 gattattatc gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac
    16801 aagcaataac aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt
    16861 taggaggaat gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc
    16921 acgaaaaaag atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac
    16981 tcttttgaac gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa
    17041 ctttataaag atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac
    17101 actcaattaa gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa
    17161 agagcagaag aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac
    17221 acgaaagcgg gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc
    17281 gtccaatata tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc
    17341 gcactttttc cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca
    17401 agacaagctt tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag
    17461 acagcgattg aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac
    17521 tatgtaaaag tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag
    17581 gaaattcttg atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac
    17641 ttgttctata cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata
    17701 ttaattgtgc tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt
    17761 gtagtcaatt tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta
    17821 tctcaaaaaa gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa
    17881 tttatgagag atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt
    17941 acaccagaga aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt
    18001 ttgatcgcaa aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa
    18061 gaattgaata ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa
    18121 tctgtttatt taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc
    18181 gtaaagaata tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta
    18241 ttgaacaagt ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa
    18301 atgaagaaga acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag
    18361 cgccgtacaa aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt
    18421 atgagaacag atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt
    18481 tatgttggag atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt
    18541 catgcattag gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac
    18601 tctatattat tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat
    18661 aacaaaaatc ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta
    18721 gcatttggga gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa
    18781 acttttattc gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat
    18841 gatccgagtg tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac
    18901 agcgtgagat cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca
    18961 gatacaccgc tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa
    19021 gttgataagt tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg
    19081 cagttcttct atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc
    19141 aatcagatta ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta
    19201 atgttggaaa tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg
    19261 gaagtaattg tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac
    19321 atccaaacat tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc
    19381 atgctagtat ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc
    19441 aatgaactga ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca
    19501 atgttgttag aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa
    19561 caaattgtca aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa
    19621 aaattagatg aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg
    19681 gtatggtgaa aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa
    19741 tgggataatt ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat
    19801 tgaggagttg aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt
    19861 agcgatccac gatgcaatca aggcagggac agatgaacga gattactata ttgataacta
    19921 tatacgaaca atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa
    19981 accaattttt ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc
    20041 tcttttatac gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat
    20101 acacagccag tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt
    20161 cgctcagctg gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac
    20221 ttatttttta gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca
    20281 tccagatgat ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga
    20341 cttgaagaaa attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg
    20401 atctttaggg gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg
    20461 catccatttt gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac
    20521 ggcacatccc tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca
    20581 agaagggttc gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc
    20641 tatgcctgga tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata
    20701 tgaggcgata agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca
    20761 tctttgatat ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa
    20821 aatcagcaca aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc
    20881 aaacagaaat ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata
    20941 tcaaatggcg agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag
    21001 tatatacgaa aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata
    21061 caatcgtggc ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc
    21121 tatatgcctt gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac
    21181 cagagatctt tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat
    21241 ttgaagactc gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca
    21301 tcaaagatca tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg
    21361 taagtttata tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac
    21421 gatttttaga aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt
    21481 atttattgtc ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag
    21541 tatctacctt atttgtagtg aacaatttag aacaaacaca aaacgcatct actgtt
//
LOCUS       DAPBBV010000048        19755 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.048, whole genome shotgun sequence.
ACCESSION   DAPBBV010000048 DAPBBV010000000
VERSION     DAPBBV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.048"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..353)
                     /locus_tag="RD486_002237"
     CDS             complement(<1..353)
                     /locus_tag="RD486_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7663955.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIF"
     gene            688..2079
                     /locus_tag="RD486_002238"
     CDS             688..2079
                     /locus_tag="RD486_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDT7663956.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAEIDFSQEKIYR"
     gene            2138..2941
                     /locus_tag="RD486_002239"
     CDS             2138..2941
                     /locus_tag="RD486_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7663957.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGKRIVPEYNNAIRVFSKRRNPFNHMTVMFD
                     KKAILEVGNYQPLSGFEDYYLWARLLKAGYKGYNIQETLVYARTGKDMYARRGGMKYL
                     GSGLMGRYRIWKDGLGSVKDFIIVSCGHIFISLLPNQLRGKFYQTQLRK"
     gene            2974..3828
                     /locus_tag="RD486_002240"
     CDS             2974..3828
                     /locus_tag="RD486_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HDT7663958.1"
                     /translation="MKKIQQITLKMSQEIVDFCLKNQLLCYFCGGGAIGTVREQGFIP
                     WDDDLDFFMPREDYEKFYQLWVNSEKSKKYPIQKASKNYNDHNSFTTIRDADTTFIKT
                     YQRDLDIVHGITIDIFPLDVAPVSKFSRKIQKLWALVYALFCSQVVPEKHGGIMATGS
                     KILLSIFRSPRTRYKIWSFAEKQMTKYNNEPTGYVTELCVGPKYMGNVYPAKDFESAV
                     WVPFEDTEMPVPVGYDNYLSQVFGDYMQLPPEKDQVSHHEAVYIDPEHPYTMYKGKYY
                     LTKGAEKK"
     gene            3825..4526
                     /locus_tag="RD486_002241"
     CDS             3825..4526
                     /locus_tag="RD486_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDT7663959.1"
                     /translation="MITAIIIAGGVGKRMGQDIPKQFITIEGKPIIIYTLESFQHHPQ
                     VDRILVVCKSGWEETMWAYIKEFNISKVKWVITGGSKGQESINNGVQFLKDYSEDDDT
                     IIIHDGIRPLVDELVLSDVIVKCKEFGNGVTSLPYNEQIFIKKTEETTEQYVDRNTLR
                     RVSTPQAYQYGKLRAAYDRAVKEDIGMTDSSYTNTMMVDLGETLYFAAGSDKNIKLTT
                     TDDLELFKAYLKMKD"
     gene            4534..5601
                     /locus_tag="RD486_002242"
     CDS             4534..5601
                     /locus_tag="RD486_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDT7663960.1"
                     /translation="MMTLIKQPMYQEDLAKVINHTPKIKQLHGKSVLMIGASGMIGSF
                     LIDTLMAANEQLGIKIKVYAMGRNRQKLEKRFASYLELDTFEIVEGDVTEPLPKEIQA
                     DYLIHGASNTHPKAYATDPIGTIMTNLAGTEQVLKHAVATQPVRVLFLSTVEIYGENR
                     GDIEKFTEDYCGYIDCNTLRAGYPEGKRVSESLCQAYIAKHDLDIVIPRLCRTFGPTM
                     LLSDTKASSQFILNAVEQKDIVLKSEGNQYFSYVYVGDAVSAILHLLLEGEKGEAYNV
                     SSENFDLRLKELAQQLADISGKQVIFELPDEIEQKGFSKASTAVLENKKIKETGWKPI
                     FPLNESLVHTVELVKGEKYNV"
     gene            5594..6559
                     /locus_tag="RD486_002243"
     CDS             5594..6559
                     /locus_tag="RD486_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7663961.1"
                     /translation="MCEISIIVPVYKVEKYLRKCVDSILAQTFTDFEVILVDDGSPDN
                     SGKICDEYAEKDNRVRVIHKENGGLSSARNAGIDVARGKYLGFVDSDDYIDEDMYEIL
                     YENLKIHDADISSVELIPFYGDRYKKANKEKKVIILNKKEAIKSVLEGTQFYAYAWNK
                     LYRKELFKDNRYLDGKTFEDAYIIIDLLFQTEKIVVSNEEKYFYLQRNDSIMGKSFSM
                     NNFDVIEAWQYNKEKILDAFPDLHDSYYRRLCWAYFYVLDKMVLSSSYQQIPRKKTVI
                     EFLKKNRNFILTYKGFTKSRKIAIIALSFRVDWYRKLVEQKNKKN"
     gene            6604..7578
                     /locus_tag="RD486_002244"
     CDS             6604..7578
                     /locus_tag="RD486_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7663962.1"
                     /translation="MCRISIIVPVYNVEKYLKKCVDSILGQTFTDFELLLIDDGSTDN
                     SGSICDELAKTDNRIKVIHKENGGLSDARNIGIEVAKGDFIGFIDSDDYIDEDMYAFL
                     YNNILKYDAELSMCGIYDVHKNKEIKKLTPFSQLVTKSEAIELVLDGKLVVANAVSKL
                     YKKELFENVRYPKGKIAEDAAVILKIINQCNKIHVDTSQKYYYYHRGDSITSKKFTKK
                     DFDIIDVWNENEKWIIKNYPQMYDKVHTRVCWAYFVVLDKLVLTEEKGLYQEKKQVRE
                     YLIDNFFFIIKNKRLTFQRKISMLLLTFGIAAYKIPVKYQYKKVKAVN"
     gene            7601..9136
                     /locus_tag="RD486_002245"
     CDS             7601..9136
                     /locus_tag="RD486_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HDT7663963.1"
                     /translation="MKKSRLEYSLINSSISMFIYILRIVIQFVGRSFFIYFLGAKYLG
                     LNGLFTNILSFLSLAELGIGSSIIYSLYKPLAQKDESKVKALMNLYKKTYEFIGIFIG
                     IVGVLIIPLLPLFIKNSTDIPHMYRYYVLFLLNSVLSYFFTYKRSLAIADQKNYLVAI
                     NDFAFLFFMNIVQVIALYFYSNFTLFLIVQILFTLFSNINISRTVDKRYSYLKEKDVV
                     SLDKQTKDEVKKNVIGNMSSKIGGVIVMGTDNILISTFVNLTAVGIYSNYSLIVTSVQ
                     NLCKQITNSITASVGNFAVSNKKKDSFELFKKHFFINHSLIFFSSILLLTLMNPFISL
                     WVGAKYMLPMSTTILIVLNYSVQVYRNTSFVFIESFGLYWSQRKKPIIEAGVNLLLSL
                     LLLIVFDMGINGVLIGTIGSSLGFVIWYEAFIIYKTVFEKRFIHFFLTFWRSFIELII
                     SAIVVFLLNEYLANGGSTFLQFITKTLITIVTTSILYLLLYFRREEFTFIKKILFRYI
                     LKK"
     gene            9193..10308
                     /locus_tag="RD486_002246"
     CDS             9193..10308
                     /locus_tag="RD486_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7663964.1"
                     /translation="MGGASIVASKIAKGLIDSGHEVFFVSYLESEKPQVESKYYDLYE
                     KKIFLFKNFSRFHKILEYRLFGGFVPSRYIKKEKEQLKKVLKKEKPDVIIFNTFIPSV
                     LFSEFLKYEFPTVKLITWMHSDPDYSLNHIAKFYKKEYRKSFERVDSIFCLSQDTKEK
                     LSLYNNHIKVIYNPLTLSGSSLISNLDKKIISFTARYDINIKGFDYLCEVAKNLPVGW
                     AIRIAGDGTEEERKELKRLIEKNGVLDKIICAGALFGDELINHYIESSIFISTSRSEG
                     LPLVLIEAMTYGLPVISFDHGGAKEILQDGNYGILIKNFDVQDMNNEIEKLSNNRLLM
                     EKYQKFSLERAKDFNEKKIIGEWQTLLNELGNEDVRN"
     gene            10305..11720
                     /locus_tag="RD486_002247"
     CDS             10305..11720
                     /locus_tag="RD486_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDT7663965.1"
                     /translation="MRTSIKNFNLWKEWYLYIFFIGMIIRAINFYSLLPSTFDSIFFK
                     LIGISGVLLLGIDFIIKFNKRKVTYNILLIAYMVILVITSFVHKEYGLGENLKTIMWA
                     ILQYFLIYQFAFENSDNKRFFKRISWGFIYSWFVLVSMSMVLFFGKFGYEKYYNARHR
                     IRIGFLESRLFGTFSDINNAAIASLVVIVLILFYLYNKKVTGLNKIIFLINLPLQFIY
                     IVLSGSRSTYVVSIIIVAISSFIVVLKRNGTKKDLKNYILAIVSSIGSVLILFALFNA
                     TKILFQELLPHLKEINFFNFTERHKELMNNSQHINNTQTPDNTLVRKDVAENTDISNA
                     RITIWKSAWEIFKTSWLIGVSPKNVVSYAQSIIPDGYIAKVGIAIHNAYLNVLTSTGI
                     LGIIPFMAFLIKSFVLNVYRIIYNKCIGKDYHFVYCLVILSYALYAALNNELVYENTV
                     GTFVFWLFLGRVNSKNNSSYF"
     gene            11753..12700
                     /locus_tag="RD486_002248"
     CDS             11753..12700
                     /locus_tag="RD486_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDT7663966.1"
                     /translation="MLNYLITGGAGFIGSTLANYLGKENNVVVIDDLSMGKKENLDES
                     KHITFIEGDVADKNLMEKVMKEYHFDYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(12740..13900)
                     /locus_tag="RD486_002249"
     CDS             complement(12740..13900)
                     /locus_tag="RD486_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDT7663967.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            14065..15240
                     /gene="mltG"
                     /locus_tag="RD486_002250"
     CDS             14065..15240
                     /gene="mltG"
                     /locus_tag="RD486_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDT7663968.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            15376..15855
                     /gene="greA"
                     /locus_tag="RD486_002251"
     CDS             15376..15855
                     /gene="greA"
                     /locus_tag="RD486_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDT7663969.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            16023..16754
                     /locus_tag="RD486_002252"
     CDS             16023..16754
                     /locus_tag="RD486_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HDT7663970.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDIEVIRI"
     gene            16751..17818
                     /locus_tag="RD486_002253"
     CDS             16751..17818
                     /locus_tag="RD486_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7663971.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            17825..18457
                     /locus_tag="RD486_002254"
     CDS             17825..18457
                     /locus_tag="RD486_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7663972.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            18597..19262
                     /locus_tag="RD486_002255"
     CDS             18597..19262
                     /locus_tag="RD486_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDT7663973.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            19290..19583
                     /locus_tag="RD486_002256"
     CDS             19290..19583
                     /locus_tag="RD486_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HDT7663974.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(19651..>19755)
                     /locus_tag="RD486_002257"
     CDS             complement(19651..>19755)
                     /locus_tag="RD486_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDT7663975.1"
                     /translation="DFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         6862 a         2787 c         3783 g         6323 t
ORIGIN      
        1 tcaaatattc ctttagaaaa taaacgataa agtgttctca taccgcatga aacaggcctt
       61 tcttttcgcc cgataatgac gtcaggcgtc caaccaagag tgactttctc tttaatgtaa
      121 tctacttcat gagcaggtaa ttgaatgact tttctaccac attttttctt attttcttta
      181 tactggtgcc aataatcaag agcagtcttg ccttgcttga acttattgac tacattataa
      241 atagtttgta tagcacgtcc cattcggtta gcgatttcaa ccggcttatt atgttgaaga
      301 taatatgatt ctatcattgt cagttcgtct atggtaagat gtttgtaggt catttatggt
      361 tacactcctt tgttttcttt cgtcggaaat acaatttgag tgtaccataa atgccttttt
      421 atttttctaa cttaatttta caattcgcgt tatatgaata ttgtaacttg tgaataagga
      481 attagcagga gaatactagt tcagcataaa ggaagtgatg ggacttctga gacaactttc
      541 tgttatgcag aaatacacat ataaacagac aataaacgct tttccccgtt tcttttaatt
      601 tcctttacaa tttggttatt cactaggttt ttaaactttg ctatggtaag atgatagagg
      661 cattatttta tggttaggag tgtatatatg aataaaaatg gggagtggaa tgcggcacgc
      721 agaatattca ttattcttat ggatgtactt gtattaaatg tatcgatcta tcttagtttt
      781 ttgctgaaat tccagggaga agtaccagtg agaaacttag aaacctttca gcattcagca
      841 atttttattt ccatcatctt tattgcgttg aatattttgt taggagctta tgtattctat
      901 aaccgaatga tcagtgatat tgtcttcatt actgttattg gacaagtact aatagcattg
      961 gggatcatgg tagttacttt tgctggccga tggtttgcat ttccgcgtgg cgtcattttg
     1021 atctcgttta tcctaggtac gatattactt agtgtttacc ggatagtcgt ttacaaactg
     1081 tacttaagag tcagtcgtga taagaaagtc cttatcgtgg gtttggagaa agatgtcgca
     1141 ccagctatcc aaaattttca atctaagaaa aacaataaac ataaggttga agcagtggca
     1201 atcgataatt attacgaaaa tacaaaaaaa ttgatcgatg atatggatat cgtctatttg
     1261 gcttctaaaa tcccagaaga tgaaaaaatc aacatttatc aattagtgac taaaaaagag
     1321 aagaaattat ttttaaatac gacttttgag aatctgacaa tgataaatcc gaatattatg
     1381 aattttgaag atgaaagcat cattgaagct tctgggttca gaatccaacc agaatacgaa
     1441 ctattcaagc gtctctttga tatcatcgtt tcgcttattt tactgatcct cgcctcacct
     1501 tttatgctaa tcacagcgat tttggtaaaa acaacttcac ctggaccaat catctataaa
     1561 caagtacgta ttacgaaaaa tcaaaaggaa ttttcaatct ataaattccg ttccatgagt
     1621 gcgacagctg aagcaaaatc aggaccagtc ttggctaaaa gtaacgatgc acgtgtgaca
     1681 ccagtaggta aatttatccg tgctgtacgt tttgacgaat tacctcaaat ctttaatgta
     1741 ttgaaaggcg atatgtcgat tgtcggtcca aggccagaaa gaccattttt cgttgatcag
     1801 ttcaatgaag aaaatcctta ttattactta agacacaatg tacgtgcggg aattaccgga
     1861 tatgcacaag tatacggaaa atatgtatca gattataaca gtaaactacg ttttgatttg
     1921 ttgtatatca aaaaatattc attactatta gatttgaaga ttttacttca aacaatcaaa
     1981 atcttatttg ataagatgtc atctcaagga ctagatgaag atgaaaatat tagttcatta
     2041 gcagaaatcg acttttcaca agagaaaatt tatcgctaga ttggaaaaat tttgagcaaa
     2101 gaggtaggag agaacattgg aaaataaaaa tgtaagtatg ctgctttctt tatatgataa
     2161 agaaaagcca gagtatttaa aggaagcatt aactagtatt tttgagcaaa cagtaatgcc
     2221 aaaagaaatt gtattagttt atgacggccc tataaatgaa aaacttcaag tagttgtcac
     2281 ttatttccaa caaaaagatc ctcacttgtt tacagttgta aaattagaaa aaaatcaagg
     2341 attggggatt gctttagcaa ttggattaga acatacgaaa aatcgcttag tagccagaat
     2401 ggatacagat gatataatgg aaccccaacg attagaaaaa caattagaga tcttccaaaa
     2461 agatccagaa atagcgattg ttgggagtaa tattgaggaa tttactggca cgcttagcaa
     2521 tgttatcgga aaaagaattg tacctgaata taacaatgca attcgtgtat tttctaaaag
     2581 aagaaatccc tttaatcata tgaccgttat gtttgataaa aaagctattt tggaagtggg
     2641 aaattaccaa ccattaagtg ggtttgaaga ttattatctt tgggcaagat tattaaaggc
     2701 aggttataaa ggatataata ttcaagaaac attagtctat gcgcgaactg gcaaagatat
     2761 gtatgcaaga agaggcggaa tgaaatatct tggttctggt cttatgggtc gttatcgtat
     2821 ctggaaagac ggtttagggt cagtaaaaga ttttataatt gtttcttgcg gacatatttt
     2881 tattagctta ctaccaaatc aattaagagg aaaattttat caaacgcaat taagaaaata
     2941 ggaggttttt ctttgtatag cactgatcca aaaatgaaaa aaatacaaca gattacgttg
     3001 aaaatgtctc aagagattgt tgatttttgt ctaaaaaatc aacttctttg ttatttctgc
     3061 ggtggtggtg ccatcggtac tgtgagagaa caagggttta ttccatggga tgatgattta
     3121 gatttcttta tgcctagaga ggattatgaa aaattttatc aactatgggt taattcagaa
     3181 aaaagtaaaa aatatcccat acagaaggct tctaaaaatt ataatgatca taattctttt
     3241 acaactatcc gcgatgcaga tactacattt attaaaactt atcaaagaga tttagatata
     3301 gtccatggaa ttactattga tattttcccg ttagatgttg cccctgtttc gaaatttagc
     3361 cgtaaaattc aaaaactatg ggctttagta tatgctttat tttgttctca agtcgtccct
     3421 gaaaaacatg gtggaataat ggctacaggt agtaagatac tcttatctat tttccgctca
     3481 cctcgtacga gatataagat atggtctttt gctgaaaaac aaatgacaaa atataataat
     3541 gaaccaacgg gctatgtgac tgaactttgt gtcggaccta aatacatggg aaatgtttat
     3601 cctgcaaaag actttgaatc tgctgtgtgg gtgccattcg aagatacaga gatgccagta
     3661 ccagttggtt atgataatta tttaagtcaa gtttttggtg actatatgca gcttccgcct
     3721 gaaaaagatc aggtttctca tcatgaagca gtttatattg atccagaaca tccatacaca
     3781 atgtacaaag gaaaatatta tttaactaaa ggagcagaaa aaaaatgatt acagctatta
     3841 ttattgctgg tggtgtgggt aaacgaatgg gacaagatat cccaaaacag ttcattacaa
     3901 ttgaaggaaa acctattatt atctatactt tagaatcatt tcaacaccat cctcaagttg
     3961 accggatttt agtcgtttgc aaatctggtt gggaagaaac gatgtgggcg tatatcaaag
     4021 aattcaatat tagcaaagtc aaatgggtca ttacaggtgg atcaaaggga caagagtcga
     4081 tcaataatgg tgttcagttt ttgaaagact attctgaaga tgatgatacg atcatcatcc
     4141 atgatggaat ccgtccacta gtagacgaac tggtattgtc agatgtaatc gttaaatgta
     4201 aagaatttgg taacggtgta acctctctac cttacaacga acaaattttt atcaagaaaa
     4261 cagaagaaac gacggaacag tatgtcgatc gtaacacatt gaggcgtgtc tcaactccac
     4321 aagcttatca atacggaaaa ctacgggcag catatgaccg ggcagtgaaa gaagacatcg
     4381 gtatgactga ttcttcttat acgaatacca tgatggtaga tttgggagaa actttatatt
     4441 ttgctgctgg ttctgataaa aatatcaaat tgacaacaac agatgatcta gaattgttca
     4501 aagcatattt aaaaatgaaa gactaggtga aagatgatga cgttgattaa acaaccaatg
     4561 taccaagaag atttggcaaa agtaatcaat catacaccaa aaataaaaca gctacatgga
     4621 aaatccgttc tgatgattgg tgcttctgga atgatcggct cttttttgat tgatacgttg
     4681 atggctgcta atgaacaact aggcatcaaa atcaaagttt atgcaatggg cagaaaccgt
     4741 cagaagcttg aaaaaaggtt tgccagttat cttgaattag atactttcga aattgttgaa
     4801 ggtgacgtca cagaaccctt accaaaagaa attcaagctg actatttgat acacggtgca
     4861 agtaacacac atcctaaggc ttacgcaact gatccaatcg gtacgatcat gactaatctt
     4921 gcaggtacag agcaagtatt gaaacatgca gtagcaaccc aaccggttag agtattattt
     4981 ttatcaacag tagaaatcta tggcgaaaat cgaggcgata tagaaaaatt cacagaagat
     5041 tactgtggat acatcgattg taatacactg agagcaggct accctgaagg aaaaagagtc
     5101 agtgaatcat tatgccaagc ctacatcgca aaacacgacc tcgacatcgt gattccaagg
     5161 ctttgccgta cgtttggtcc gacgatgctt ttatctgata cgaaagcatc ctcacaattt
     5221 attttaaatg cagtcgaaca aaaagatatt gttttaaaaa gtgaaggaaa ccaatatttt
     5281 tcgtatgtat atgttggaga tgctgtttct gctattcttc atttactgct tgaaggagaa
     5341 aaaggagagg cgtacaacgt ttcttcagaa aactttgatt tacgactaaa agaattagcc
     5401 caacagctag ctgatatcag cggcaaacaa gtaatttttg aattgccgga tgagattgaa
     5461 caaaaaggtt tctcaaaagc tagcacagca gtacttgaaa ataaaaaaat taaagagaca
     5521 ggttggaaac caatttttcc tttgaacgaa tcattggttc atacagtaga attagttaaa
     5581 ggtgagaaat ataatgtgtg agattagtat tattgttcct gtgtataaag ttgaaaaata
     5641 tttaagaaaa tgtgtagatt cgattttagc ccaaacattt actgattttg aagttatatt
     5701 agtagatgat ggatctcctg acaatagcgg gaaaatctgt gatgagtatg ctgaaaaaga
     5761 taatcgagta cgtgtgatcc ataaagaaaa cggcggatta agcagtgcta gaaatgcggg
     5821 gattgatgtt gcgagaggca aatacttagg ctttgttgac agtgatgatt atattgatga
     5881 agatatgtat gaaattttgt atgagaattt gaaaattcat gatgccgaca ttagctctgt
     5941 tgaattgatt cctttttatg gtgatagata taagaaagct aataaagaaa agaaagtaat
     6001 tatattaaat aaaaaggaag caataaaatc tgttttagaa ggaacgcaat tttatgcata
     6061 cgcatggaat aaactttatc gtaaggaact ttttaaagat aatcgttact tggatggaaa
     6121 aacatttgag gatgcatata taataataga tctattattt caaacagaaa aaattgttgt
     6181 ttccaatgaa gagaaatatt tctatcttca aagaaatgat agtattatgg gaaaaagttt
     6241 ttctatgaat aatttcgatg ttatagaagc atggcaatat aacaaagaga agattttaga
     6301 tgcttttcca gatttgcatg attcctatta tcgccgacta tgttgggcat atttttacgt
     6361 gttggataaa atggttttat caagtagtta tcaacaaatt ccacgtaaaa aaacagtaat
     6421 tgaattttta aagaagaaca gaaattttat attaacttat aagggattca ctaaatcgcg
     6481 caaaatagct attattgctc tgagctttag agtagattgg tataggaaat tggttgaaca
     6541 aaaaaataaa aaaaattaga atgtttaaat tagtaaataa aagaaaagga attgaaaact
     6601 aaaatgtgca gaataagtat aatagttcca gtttataatg ttgaaaaata tttaaaaaag
     6661 tgtgtcgatt caattctagg ccaaacattt accgattttg aattattatt aattgatgat
     6721 ggttctacag ataattcagg aagtatatgc gatgaacttg cgaaaacaga caaccgaata
     6781 aaagtgatac ataaggaaaa tgggggtcta agtgatgcca gaaatattgg tattgaggta
     6841 gcaaagggag attttattgg gtttatagat agtgatgatt acattgatga agatatgtat
     6901 gcatttttat ataacaatat attgaaatat gatgcagagt tatcaatgtg tggtatttat
     6961 gacgtccata agaataaaga aattaaaaag ttaactcctt tttctcaatt ggttactaaa
     7021 tctgaagcaa ttgaattagt attagatggt aagctagttg ttgctaatgc agtaagcaag
     7081 ctatataaaa aagaattatt tgagaatgtg agatatccaa aaggaaaaat tgctgaagac
     7141 gcagcagtaa tactgaaaat tatcaatcag tgtaataaaa tccatgttga tacttctcaa
     7201 aaatattatt attatcatcg tggagatagt attactagta aaaaatttac aaaaaaagat
     7261 tttgatataa ttgatgtatg gaatgagaat gaaaaatgga ttattaaaaa ttatcctcaa
     7321 atgtacgata aagtacatac tagagtttgt tgggcttact ttgttgtgtt agataaatta
     7381 gttttaactg aagaaaaagg actgtatcaa gaaaaaaaac aagtaagaga gtatttaatt
     7441 gataatttct tttttattat aaaaaataaa cgattaactt ttcaaagaaa aatatctatg
     7501 ttattgctta cttttggaat tgctgcgtat aaaataccgg ttaaatatca gtataagaaa
     7561 gtaaaggctg ttaattaatg ctttagttag gatgaattag atgaaaaaaa gcaggttaga
     7621 gtattcttta ataaattctt ctatatcaat gtttatatat attttaagga tagtaataca
     7681 atttgtaggt agaagttttt ttatttattt cttaggagcg aaatatttag gattaaatgg
     7741 tttatttaca aatatactta gtttcttgtc gttggctgaa ctaggcatag gctcttctat
     7801 tatttattcc ctatacaaac cattagccca aaaggatgaa agtaaagtaa aggctttaat
     7861 gaatttgtat aagaagacat atgaatttat tggtattttt atcggcatag taggagtatt
     7921 gattattccg ctgttacctc tatttattaa aaatagcaca gacataccac atatgtatcg
     7981 atattatgta ttatttttat taaattcagt tcttagttat tttttcacgt ataaaagatc
     8041 acttgcaata gcagatcaaa aaaattatct ggttgcgatt aatgattttg cctttttatt
     8101 ctttatgaac attgtacaag taattgcttt gtacttttat tctaatttta ctctatttct
     8161 aatagtgcag attttgttta ctctattttc taatataaat atttccagaa cagttgacaa
     8221 gagatattca tatttaaaag agaaagatgt agtttctcta gataagcaaa caaaagatga
     8281 agtaaagaaa aatgtcatag gtaatatgtc ctcaaaaata ggcggggtta ttgtaatggg
     8341 gacagataat atattaattt ctacatttgt taatttaaca gctgtaggaa tttattctaa
     8401 ctattcattg attgtcacaa gtgtgcaaaa tttatgtaag caaattacta attctatcac
     8461 ggcaagtgta ggaaattttg ctgtatcaaa taaaaaaaag gattcatttg agctatttaa
     8521 aaaacatttt tttatcaacc actcactaat ctttttttct tctatattgt tattgacttt
     8581 aatgaatccc ttcattagct tgtgggtagg agccaaatac atgctaccta tgtcaacgac
     8641 tattttaatt gttttaaatt atagtgtaca ggtttataga aatacatcct tcgtttttat
     8701 agagtcattt ggtttatatt ggtctcaacg gaaaaagcct ataattgaag caggtgtaaa
     8761 cttgttatta tctttgcttt tgttaatagt ttttgatatg ggaatcaatg gagtacttat
     8821 agggactatc ggatcgtctc taggatttgt gatttggtat gaagcattta tcatatataa
     8881 aacggtattt gagaaacgtt ttattcattt ctttttaact ttctggcgaa gttttataga
     8941 attaataatt tcggcaatag tcgtttttct attaaatgaa tatttagcaa atggaggcag
     9001 tacgttcctt caatttataa ctaaaacctt aataactata gtaacaacat cgatattata
     9061 tttgttatta tattttagaa gagaagaatt tacatttatc aaaaaaattc tttttaggta
     9121 tattttaaaa aaatagcttt ctataaagga gtgttttatt tgaaaatagc tatactatct
     9181 ccagctttct caatgggagg agctagtatc gtggcctcaa aaattgcaaa aggattaata
     9241 gatagtggcc atgaagtttt ttttgtttct tacttagaaa gtgaaaaacc acaagtagaa
     9301 tctaagtatt atgatttata cgaaaaaaaa atttttttat ttaaaaattt ttctcgattt
     9361 cataagatat tagagtatag attgtttgga ggctttgttc ctagtagata tataaaaaaa
     9421 gaaaaagaac aactaaaaaa agttctaaag aaagaaaaac ctgatgtcat catattcaat
     9481 acttttatac ctagtgtact attctccgaa ttcctaaagt atgaatttcc aacagtgaaa
     9541 ttaattactt ggatgcactc tgatcctgat tacagcttaa atcatattgc taaattttat
     9601 aaaaaagaat atagaaaaag ttttgaacgc gtggattcca ttttttgtct ttcgcaagat
     9661 acaaaagaaa aactttcatt atacaataac catattaaag ttatttataa cccattgaca
     9721 ttaagcggct ctagtttaat aagtaacctt gataaaaaaa ttatttcatt tactgccaga
     9781 tacgatataa atattaaagg gtttgattat ttatgtgaag tagctaaaaa cttacctgtt
     9841 ggatgggcta taaggattgc tggagatggt acagaagaag aacgtaaaga gctgaaaaga
     9901 ttaattgaga aaaatggtgt gttagataaa attatttgcg caggtgcatt atttggagat
     9961 gaattaatca atcattatat agaaagttct attttcatat ctacttctag aagtgaggga
    10021 ctaccattag tgttgataga agcaatgact tatggattac ctgtaataag ttttgatcat
    10081 ggtggtgcta aggaaatatt acaagatgga aattatggaa ttttaattaa gaattttgac
    10141 gtacaagata tgaataatga gatagaaaaa ttgtctaata atcgtttact tatggaaaaa
    10201 tatcaaaaat tctctttaga aagagctaag gattttaatg aaaaaaaaat aattggtgaa
    10261 tggcaaacat tgttaaatga attaggaaat gaggatgtta gaaattgagg acttcgatta
    10321 aaaattttaa tttatggaaa gaatggtatc tatatatatt ttttataggg atgattattc
    10381 gtgcaataaa tttttatagt ttattaccgt ccacttttga tagtattttt tttaaactta
    10441 taggaatttc aggagttttg ctattaggga tagatttcat aattaaattt aataaaagaa
    10501 aagtaactta taacatttta ttgatagcat atatggtgat tttagtaata acgagttttg
    10561 ttcataaaga atatggtcta ggagaaaact taaagactat aatgtgggca atcttacagt
    10621 attttttgat ttatcagttt gcttttgaga atagcgataa taaacgattt tttaaaagga
    10681 taagttgggg atttatttat agttggtttg ttttagtatc aatgtcaatg gttcttttct
    10741 ttggtaaatt cggctatgag aaatattata atgctagaca taggatcaga attggttttt
    10801 tagaatcaag actgtttggg acgttttctg atattaacaa tgctgctata gcatctttag
    10861 ttgttattgt cctaatctta ttttatcttt ataataaaaa agtgacagga ttaaataaaa
    10921 tcattttttt aattaatctt ccattacaat ttatttatat agtattaagt gggtcacgat
    10981 ctacctatgt ggtaagtata ataatagttg ccatatcatc ttttattgtt gtgttaaaac
    11041 gaaatggaac aaaaaaagat ttaaaaaact atatccttgc tatagtatct tctattggtt
    11101 ctgttctgat tttattcgct ttgtttaatg caactaagat actttttcaa gaattattac
    11161 ctcatttaaa agaaataaat ttttttaatt ttacagagcg tcataaagaa ttaatgaata
    11221 atagtcaaca tattaataat actcaaacac ctgataatac tcttgttagg aaagacgtag
    11281 ctgaaaatac agatatttct aatgctagaa ttactatatg gaaaagtgca tgggaaatat
    11341 ttaaaacaag ttggcttatc ggagtctctc cgaaaaatgt agtatcttat gcacagtcaa
    11401 ttattccaga tggatatatt gcgaaagtag gaattgccat tcataatgca tacttgaatg
    11461 tattaacatc gacaggtatt ctaggaataa ttcctttcat ggctttttta ataaagagtt
    11521 ttgtgctgaa tgtttatcga atcatctata ataaatgcat tggtaaagat tatcattttg
    11581 tttactgttt agttatttta tcttatgcac tatacgcagc tcttaacaat gaattagtct
    11641 atgaaaacac tgtaggaacg tttgtttttt ggctattttt aggaagagtt aatagcaaaa
    11701 ataattctag ctatttttag taataaattt tatcttgaaa agaggagaaa aaatgttgaa
    11761 ttacttgatt accggtggcg ccggcttcat tggctcgacg ctcgcgaatt atctaggaaa
    11821 agaaaacaat gtagttgtga tcgatgattt atcgatgggg aaaaaagaga atctggatga
    11881 atcgaagcac atcacgttta ttgaagggga tgtcgctgac aaaaatttga tggaaaaggt
    11941 catgaaagaa taccatttcg attatatttt ccatctagct gctgtagcta gtgtggcaga
    12001 ttctgtagaa cgtcctctag aaactcatcg tgtaaatttt gacagtgcgc ttttattgct
    12061 tgaattggta cgaaaatatc aatctggttt aaaacgattg gtatttagtt catcagctgc
    12121 agtttatggc gatgaaccaa cgttgccaaa aaaagaagaa tcggtcatcc gtcctttaac
    12181 accatatgcc atcgataagt ttgcagcaga acaatatgtt ttggattact gtcatttata
    12241 tgatgttccg actagtgctg tccgattttt taacgtttat ggtccaaatc aaaatcctaa
    12301 ctctccatat agcggagtta tttcgattct agtggaccga tacaaaaaac aattggcagg
    12361 agaaaaaaca gaatttactt tatttggtga tggtagccaa tctagagact tcgtttatat
    12421 agaagatgtt atacaagcac ttttacttgt tgctaaggaa gaaaaagctt taggacagca
    12481 attcaatgtc ggtacaggaa aaagcactac gctacttgaa ttgattcatt caattgatca
    12541 aatcttagga acagagctag cgcttaaata tgaagcggag cgttcagggg atattcgtga
    12601 ttctttagcg gatatttcaa agatccgttc tttaggttat caacccaaat ttgatatatt
    12661 gaacggaatg gaacgttatt taaagacaga aatcgattga aacaaaaaac cagcatcctg
    12721 ctggtttttt tgtctcgact tagcttttta aattaacacc ttccatcagt tcgtaaatct
    12781 gatttcttaa atcagtggcc ggcaatttga tgtttttatc agattggata ttactttcca
    12841 tgacgattgc atcttttgtg tcttttttca tcgccgctac tgcatggaat cgattgatat
    12901 ttccctgagc aaggatataa tcatttccac tgtaaacacc gccgctgtaa ggatgtttat
    12961 caccattatt ttgccacaat gagaaaagta gttcttttgg tataatatcg ccagacagaa
    13021 cactggtaaa gaatttgttc aagtcataaa cagacatact tatatttcct gtgcctaatt
    13081 catttcggat gtctgtttca ggctcgacca atgcttttga ataatcgtca gttgcagaca
    13141 tttggtaaga tacagcatgc tgaggggaat tttttacatt ttcataaaaa tctgtatgtt
    13201 ctagatggag tggccgaatg atttcttttt ttaaaagagt ttcataaggc tgattcatta
    13261 gtttgatcaa tacccctgta agcaatgtat aatttaatgg ttcataatga tacgtatcat
    13321 aaccagtaaa tttcaaatga tgaagggcaa actgaatgat ctcactatct gacataggtt
    13381 tttttggaga agcggttcga tgaagaccag agcgcatgta aagcatattt ttgattgaga
    13441 tttgctgact tccaggaatc tgaggataaa attcagatag ctttgtgtca aaagttatct
    13501 tgccagattg aatttgtttt aggataagta aagcagtcat cgctttttgg atcgaaccga
    13561 tttgatagta aagagaagga gaattcgatt cttttatgcg tagatttgcg tacccatatc
    13621 ctttttctaa tatcactcga ttatttttgc gtacataaat cgaaccgata taatctgatt
    13681 tttgcagtaa ttgatcaatt ttgctggcaa gcatctgctc attagatgtt aaattggaag
    13741 caagttgtgc gggttccgtt ttataaattt gtggttgagg ttgttttgtt aattgccatc
    13801 ctgtaatgat gcctgttgaa aagaagctga cagccagcaa caaaactgcg agaaaagaaa
    13861 gagagatctg ctgttttttt tgatgttttc cttttgccat attaaatcct tcctatccat
    13921 ttttaactat ttttcattgt aatcctcaaa aagagcattt gccacttaca attttgacat
    13981 aatatttggt aaaataattc acggcagtag aaatttcatg tataataaac agagttacga
    14041 agatgatagt aaggaggagt tgttttgtca ggaaacaaac aacacccaag caaagacaaa
    14101 aaagaagcca gtaaggcagc tacagcagat ataatcgaca agcggagaaa tctgcgtaaa
    14161 aaagaagata agatcgtgag gaagatcatt ttagtgatcg ctcttacatt attgattatt
    14221 ggcggatttc tcgggtttac cgtatatcgt tatgtagata gcgggttgaa gcctttagat
    14281 aaatcggacg accaattagt ccaagtggaa atcccaagcg gctcttctaa taagcagatt
    14341 ggcgaaattt tggagaaaga caatattatt aaaagtggga ttgttttcaa ttattataca
    14401 aaatttaaaa acttaactgg ctttcaagct ggttattatc agttagcgcc taatatgact
    14461 cttgatgaga ttggcaagca gttgcaagaa ggcggcacat ctgagccaac aaaagttgca
    14521 gatgggaaaa ttgccattcc agaaggctac gacatcgatc agattgctga gcgggtagcg
    14581 aaggtaactg gtaaagacaa gaaagaattt ttagatttag taaatgatga gactttcttt
    14641 aacgagttgt atcaaaaatt cccagaattg ttggaaagtg cctctaaagc tgagaacaca
    14701 aaataccgtt tggaaggcta cttattccca gctacttatg attactacac gagtacttcg
    14761 cttaaggatc ttgtgattga gatggtgaac aaaacaaata cggtcatgca aaactattat
    14821 tcagctatca aacagaaaaa tttgactgta caagaagttt taactttggc ttctctagtt
    14881 gaaaaagaag gcgtaaaaga aaatgatcgt aaaaatattg cacaagtctt ctttaaccga
    14941 atcaaggcaa atatgccact tcagtcagat atctctgttt tatatgcatt aggagaacat
    15001 aaagaattgg tgacgtatga agatacagct gtagattcac catacaattt gtataccaat
    15061 accggctatg ggcctggtcc ttttgacaat ccaagcgaag aggcaatcaa ggcagtatta
    15121 gaaccagcag aaaatgacta ttattatttc gtagcagata cgagcactgg aaatgtttat
    15181 ttcgctaaaa cgtatgaaga acatatggaa ctagtgcaaa aatatgtaaa taattcttag
    15241 aaaaacaggg gctagtcatt gatcattttt agaaaaacat ttacatttta agaaaagcgt
    15301 ggtaatcttt tttggactat attcctcaaa agattacctt ttgcggtatt ttatcgaaaa
    15361 aaggagacgt tacacatggt agagaaagtt tatccaatga ctctagaagg taaagaaaaa
    15421 ttagaaaaag aattagaaga actaaaaaca gttaaacgcg gagaaatcat tgaacgaatc
    15481 aaaatcgctc gcggtttcgg agatctttcc gaaaactccg aatacgaatc agctaaagat
    15541 gaacaagcat ttgttgaagg aagaatcaca acaattgaaa atatgatccg ttttgcacaa
    15601 atcatcgata atgacggcgt agatgcagat gaggtatcga tcggtaaaac agttacgttc
    15661 atcgagttgc ctgatggaga tgaagaagag tacacgattg tcggaagtgc tgaagcagac
    15721 ccgttttctg gaaagatttc caatgattct cctatcgcgc aagcattgat tggcaaacgt
    15781 aaaaatgatg aagtaaccat tgctacacca ggtggcgata tgttagttaa aatcgtcaaa
    15841 gtagaacaag cgtagtctga ctgaaagatc tagagagttc atcttactga tgacgcactc
    15901 tagatctttt ctctttgagt attgcaggtt tcactgaacg atcttacatc taaagtccta
    15961 tagccaacag tcaaaaaaat aggtatgatg aaatgagaat gtgtcaggag ggagaaaaag
    16021 cgatgaatag ttcttggcgt ttttttgtgg tagtcgaagc actgctgctg ttatttgctg
    16081 tttggcaaat cgtaaacaat actggacttt tgcttttagt aatattcggt attttcaata
    16141 tatatctagc tatgcgcaaa tatcctcgta ctaaatttca aaattttcaa ttgatcttag
    16201 ggagcttggt catttttttt agcttagtca acagtcctgc tttatggatg atggttgtat
    16261 tggccgtttt atttatcggg ctgaaaggtg tagagatttc aggaatagat ttgacaaaaa
    16321 atgctttttg gcgaaaaaaa cagatcatga tggtccaaac agagcaatta aaaacacata
    16381 ataatgagcg taaaagacag caattatttg gtaaccaacg tattggaaac gacgtctatg
    16441 aatgggatga tatcaacatt gccatcattt ctggtgatac tatcatcgat ttgggcaata
    16501 cacttttgcc aaaagatgat aatattgtga ttgtaagaaa agggataggc agaacacgga
    16561 tcttagtacc cctgggagtg gctattcgtt tagagcatgc gacattagta ggaaatgtct
    16621 tgtttgaaga agagcagttt tccttaaaaa acgaacagat caaaatctgc agcagtgatt
    16681 atgatgaaaa tcctcgcaga ttgaagatca ttaccaatac tttggttgga gatatcgagg
    16741 tgatacgaat atgatgggaa gaatatccaa agcaatgcta gctgtttatt cggggattgc
    16801 ggctttcctt attattctat tttcactttt cacttatttt tatgccagta accaaagtca
    16861 ttggtgggga gaattgctgc gtgcgcgttt attatacgtt ccgcttatct tccatttgat
    16921 ggcaatttca ttaggtgtag gattgatcgt atttctattg ttatcactta ttcaaaaggc
    16981 aaaatacggg aaaatcgaag aaaagcttcg tgcactttct tctggcaatt atgaatccaa
    17041 acttttgcat cagccgatcc caagcgcgtc ggatgatctg tacatcaaag atattgatat
    17101 ggaaattact aaaataaaag aaaaaatgat cgaagtatcc agtgaattac agattatgac
    17161 tagccgtcct caatatgtag atggacaaac caaagaagag attttaaaat tagaaaggca
    17221 tcgattagct cgtgagcttc atgattcagt ttcacagcaa ttatttgcag cgatgatgat
    17281 gatgtcggca ttgacggagc aagcagaaaa aagtgagaca ccagaaatgt tccgtaagca
    17341 gttgaaaatg gtggcagaga tcatcaacgc ttcccagtct gagatgcgtg cgctgcttct
    17401 tcatctgcgt ccagtcaatt tagaagaaaa aagtttaaaa caaggcattg agcagttatt
    17461 gaaggaattg cagaataaaa tccagatttc gctaaaatgg gaggtagaag atgtaaaatt
    17521 aactagttcc attgaggatc acttgttccg aatcgttcaa gaattgttat caaacacatt
    17581 aagacatgct aaggctaatg aattagaagt ctatttgcat aaaatagata acaatctttt
    17641 attacgtatc attgacgacg ggacaggatt taatatgaat gaaaccaaaa cgggaagtta
    17701 tggattgaac aatatcaaag aacgagtagc tggtattggt ggaacagtaa aaatcattag
    17761 ttttaaaggg caaggtacga gcgtggagac caaggtccct ttgatgaagg aggcatagat
    17821 aaagatgata aaagttttat tagtagatga ccatgaaatg gtacgcttag gcgtctcttc
    17881 ttatttatct atccaagaag acattgaagt gattggagaa gctgaaaatg gacgtcaagg
    17941 ctatgaaaag gcgatggcac ttcgaccgga tgtcatttta atggatctag tcatggaaga
    18001 aatggatggc atcgaatcaa caaaagcaat cttaaaagat tggccaaaag ccaaaatcat
    18061 tatcgtcaca agttttattg atgatgaaaa agtttatcct gcaattgaag caggagcagc
    18121 aggatatttg ttgaagacgt ctacagcaca tgaaatagct gatgctataa gggctacgca
    18181 acgcggcgag cgagtactag aacctgaagt gacaacaaaa atgatggaaa aaatgagtcg
    18241 gcgaaatgat ccagtattgc atgaagaatt aacgaatcga gaaaatgaaa ttttgatgct
    18301 gatttctgaa gggaaaagta atcaggaaat cgcggatgaa ttgtttatca cactgaaaac
    18361 agtcaaaacg catgtgtcga atatattagc taagttagag gtagaagacc gaactcaagc
    18421 agctatctat gcgtttaaac atggtttggt gaaataaaaa cgatgataaa gaggataatc
    18481 aaaagctgag aaaataacta ttatttttct tggctttttt acaataatga tgcttgcttt
    18541 tgtttttgga aaggctttgt tatactgaga aaagaagata ctaaaggagg aaaatggtga
    18601 aacaaaattt tgcaattgta ggccttggac gatttggcgg aagcatctgc cgtacactga
    18661 tcgaagctgg acaagaagta ctggctattg acagtaatga agatcgagtc aatgaatata
    18721 tgaatatagc cacccatgct gttgtggcaa atgcacagga tgagatgaca cttcgttcat
    18781 taggtataag aaatttcgat catgtaattg tcgctattgg agaagatatc caagccagca
    18841 tcttagttac tctgatggta aaggaaatgg gcgtaccgaa tattttagca aaagcccaaa
    18901 atgagtacca tgcccgtgta ctagagaaga tcggagcaga tcgtgtcgta caccctgagc
    18961 gagacatggg gatacggatt gcacataact tagtatcaaa gaatattcta gactacttag
    19021 agctgtcaga taaatattct ttagcagaaa tccgagtctc caatcctaaa tttttcaaca
    19081 aaacattagc tgaattaaat ttcaggcaac gttttgactt aacagtagtc gccatacgaa
    19141 gagtagatca aacggttatc gcttctcctg cagcagatga atatgttcgt gaaaatgata
    19201 atctactggt tattggagag acaggcgatg tggatattct agacgataag atgaatcaat
    19261 agaaagaaaa gagaaagtag gttgttggga tgaaattaac ggtaacgcca aaagcacaaa
    19321 agtggtttga ctcagaaatt gatctgccag aaacttacgg aatacgtttt tttggaaaag
    19381 tctacggcaa aacagaggtt catgatggtt tttcgattgg aatgtcagtt gaacagccag
    19441 aacatcctgt aaagaaagtg gaaatggatg ggacactttt ttttatcgag gaagcagatg
    19501 aatggttctt taaaggatat gatttacttg ttgattatga tcccaacctg gaggagccaa
    19561 cctatcactt taaaaaacaa taaaaaaaga gagggtgaca caatttttgt caccttctct
    19621 tttttctttt gaaaatattg ttttcagcta ttaatatcct gcagacaatt ttacttgatt
    19681 ggtttgaagc tcatgggtgg caaagtagct tttcagattg gttaaaaaaa tagccattaa
    19741 tttcttttga aaatc
//
LOCUS       DAPBBV010000049        18977 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.049, whole genome shotgun sequence.
ACCESSION   DAPBBV010000049 DAPBBV010000000
VERSION     DAPBBV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.049"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(53..451)
                     /locus_tag="RD486_002258"
     CDS             complement(53..451)
                     /locus_tag="RD486_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HDT7663976.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(643..1410)
                     /locus_tag="RD486_002259"
     CDS             complement(643..1410)
                     /locus_tag="RD486_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7663977.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            complement(1445..2668)
                     /locus_tag="RD486_002260"
     CDS             complement(1445..2668)
                     /locus_tag="RD486_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HDT7663978.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLENHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            3649..4452
                     /locus_tag="RD486_002261"
     CDS             3649..4452
                     /locus_tag="RD486_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7663979.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            5037..5492
                     /locus_tag="RD486_002262"
     CDS             5037..5492
                     /locus_tag="RD486_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663980.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            5611..6669
                     /locus_tag="RD486_002263"
     CDS             5611..6669
                     /locus_tag="RD486_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HDT7663981.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            6711..8660
                     /locus_tag="RD486_002264"
     CDS             6711..8660
                     /locus_tag="RD486_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDT7663982.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            8663..12304
                     /locus_tag="RD486_002265"
     CDS             8663..12304
                     /locus_tag="RD486_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663983.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            12704..13042
                     /locus_tag="RD486_002266"
     CDS             12704..13042
                     /locus_tag="RD486_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663984.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            13152..13373
                     /locus_tag="RD486_002267"
     CDS             13152..13373
                     /locus_tag="RD486_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663985.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            13393..15549
                     /locus_tag="RD486_002268"
     CDS             13393..15549
                     /locus_tag="RD486_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663986.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            15561..15794
                     /locus_tag="RD486_002269"
     CDS             15561..15794
                     /locus_tag="RD486_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7663987.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            15784..16650
                     /locus_tag="RD486_002270"
     CDS             15784..16650
                     /locus_tag="RD486_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663988.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            16665..18635
                     /locus_tag="RD486_002271"
     CDS             16665..18635
                     /locus_tag="RD486_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663989.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            18802..>18977
                     /locus_tag="RD486_002272"
     CDS             18802..>18977
                     /locus_tag="RD486_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663990.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARV"
BASE COUNT         6869 a         2754 c         3620 g         5734 t
ORIGIN      
        1 ccatacgtcc taaaacaagc tgtttttgct taatatgatc atctgagaga catcaaatca
       61 acttttctct caacaaatca ttcaaagctt tcgacagatt aatattctct tcagccgcta
      121 aaacatttaa atagtgttcc acagtcactg attttcgatc ataattttgc ttgtttcgag
      181 ctttagcaac tttcgtatta gcttttacga caaataaatt aacattctca gatcgcttga
      241 ttcttgcatt taactcttga acaggcgtag gcgatggaat ttctttttct tgcaactcta
      301 aaagcaccaa gtatccttcc aatacttctt gcgccatctc aaaagcatct tctaaagttt
      361 caccatgtgt atataagtct ggaaaatctg ggaatttaac tgcatattca tttcctttcc
      421 attcgaatac tgcacaaaaa aagtatttca tcgcattgca cctctctaat taaaaaataa
      481 tttttgcttt tttgtttcaa aaaaaagaat cgcctaccaa aaaaattgat aggcgatcac
      541 aagctaatta acctctaaag gagattaata ccttgctccc aaggcactat atatcttagc
      601 atacgtctga agcatcttca aacgagtaag atatattttg cattaaccta attttttttc
      661 tctataagtt ttttcatcaa actcactaga aatattaaac tggacagcaa aattgtaatt
      721 tctgcctttt ctaactttag caaaatcaat attcagcatt gatttttcat taatttcctc
      781 aactgattcc cttaaaacac gtctatcaaa attcgatatt gttttatact cattttctgt
      841 tttcgtaatc tcacgaattt taactatttc aatcagggga ttcttatata tttcagcttt
      901 ctcaaaatct cctttatttt tggcgataag atatttttta taatacatcg ccaaatattt
      961 gtataacacg atgctatatt ttttttgaaa agatgctaag tcttcaaaaa caaagaacgg
     1021 atacttcttt ttgattgaga caattaaggg aattacatct tctgaaaaac tgaaagatac
     1081 actatgctct tctaaatccc aatgaatccg atcaatagca gatacagtag tatacgtctt
     1141 atattttttg tctagattcg aaatttcata aactgcttgt ctttgcaaag tgttaactat
     1201 ggtttttagt tccgtttcaa gattttgatc aacatccatg taattaataa tcgctttaac
     1261 aggtaaatct actacgcctg ttttctttag ctttgtgggt gagatataac tgaacagcaa
     1321 ttgataaagt tcatacgact ttaaatccat tttcatgtca attgttgcta agaactcctc
     1381 attgtacttt gtcagttcat cttttttcaa aagtttttcc ttccttcacg cattttttca
     1441 gttgttaatc ataaaggttc acataaggca aataactcgt aattgatttt tcgagatatt
     1501 taacagtatt ttttattgtg taatcctcct tatgagtagc aacgtaagat aggtgattga
     1561 caactgattc aaatcctcta tctttggata aacgatcata aagcggataa actttattct
     1621 gaagtcggct cataagttta agatcgcata agtcggcaga actgatcaaa aagtttttga
     1681 ttagtaattt agtgtatttg ctattcatag ctttcaagta cgattgattc attttctctg
     1741 ttttatcttc tgcgcctttt aaataagcag ggtctctttg ttcttgctta taaggtaccg
     1801 gaactgacat ggtacgtgta agcaagaact ttatgtttgt ataagtatga cccttcttga
     1861 taagctcata gtcaatttta aaatcagtgt atttattcag ttgggcaatc ggttctttaa
     1921 ttacacgtct ttcaaagtct cgaaaagctt tatatttttt ctcaatacta aatttctttc
     1981 gtaaatctgc aatggagaaa acaggatttt ttaatctatc aagtgatttt gtactccatg
     2041 ttaagttatc tctatttgct tcatacagat taaaatcttt agtgaataat tgaaaaaaac
     2101 tgatcgcata cttgcttgtc aagttaacta cttgatcaaa tgtatattgc gtaaaatgat
     2161 tttctaagtt cgttaataaa ggcataattg aactactaaa tttaatagat actgcatcag
     2221 aaaaatcatt gaattcagta atttctagcg gtgagatgac tttgtattca gtcttaccgt
     2281 taggtttagt tctttgaatt ttaatgacag attgctgatg caatttttca ataacttgtt
     2341 ttaatcttga atgttttgaa gaagatgaac tagaagacat caacgcaaat aaagcctttt
     2401 tagatacttt gacggtatta ttaaaaggcg gatttttagg gtcaagatgt cctatagcgt
     2461 aaagataaat tttttgtggc atagcatcca tttcaacaat gctatctaca agttgattcg
     2521 ataaagtaac agttaaatca aactttttta gattgctttc ggtagtttca aatttcgggt
     2581 ttacattctt ttctgttatt ttcatacgat tgcctcttct ttctaagctt ggtacgagct
     2641 taaaaacttg gaactggtac gattccattg aataagtata gacctgtttt cgatacgtta
     2701 caataagaaa tgtatcgtaa atttataaca taactcaatg tcagtaaaac acattttatt
     2761 ttttccaatc aaatttcatt gaaaatacag cagaaatcgc tattttagaa cattttcaaa
     2821 ataaaaatcc ttttcaataa aatacgaaat tataaaaatt accaaaatta aaaaacaaat
     2881 atttttctag tttttagaaa taaattcaca tactttttct ttttttggat atattcggaa
     2941 taccacatcg ctttttgtcc acgtttgcat cgctttttgt ccacattcac atcgcttttt
     3001 gtccatgttc gcatcgcttt atgtccaccc taaaatctat ttaagattga tataaagcct
     3061 ttttggaggt tgctaaagtt ttaaagatta aaatatatat tataaatata aataaaaggg
     3121 gaagctgaag cttcctcctt ttcctttttt tcaattattc aaagttacac aagcaaaata
     3181 aactcctaga tagtgttagt tttttttaag attttttatt tttaagattt tgaaataaga
     3241 gaggagtaat cctcctttat taaatatctg ttaatatatc tgttaaatat ctgttaatat
     3301 atctgttagg ggaggcttaa tctcttggga gagtaagtat taaaggggta taaaggtaac
     3361 acttttggac agtaaaggta acaaaagtgg acagtaaggg taacagtttt ggacagcaaa
     3421 ggtaacaaaa gtggacattt gaggtatcac actaggataa gacgttacct tcggttttct
     3481 tgatttggaa ggcgaaaaaa tagaaaatta gattagtaac aaatctttgt tgactgttac
     3541 ctttagttgt gatttaattt aggtaacaag cagaaaaaat tgtttccttt aattagtacc
     3601 agattaacat gattaaagga gcgcaaaaag aagattggag agtaatcaat gtctcaagaa
     3661 gttaccgaaa agattattga tagtgatgta gatttagtat cagaacaaac aaatgcaatt
     3721 gtgcgttata acaatggtct gaatacaaca gctttgcgag gatttaagcc tgttgaaatg
     3781 gatgtgtttt gggctatttt atcaaaaatg aaacgtcaag gaacagcaga agtaactttt
     3841 gatttcaacc tctttcgtta tttggtcaaa tacgacagaa gagaaaagga cagtttttat
     3901 tctgtgttaa aagatttgag tgacaaacta ggtaatttaa cctaccgttt tgaagattca
     3961 gacgtctatg aacagctgtg gctttttcaa aaattccgga tagataaaca gaaggaaaca
     4021 gttacaatta aggcaaatga ggaatttgaa tttatcttaa actcaattgg caaaaacttt
     4081 actcgttttg aacttgataa ttttacaaaa ctaagaagta gctacacaaa agaattgtat
     4141 cgtcatctca tgcaatacag aaataaagag tggcgaaatg gttattgggt agtcaaagtt
     4201 gaagatttta gaagagcatt aagtatacct tcaagttata gaatgacaaa tattgataaa
     4261 agaatactag agcaggcgaa agaagaattt ttagctcctg atgaaaacgg aatacaggta
     4321 tttgaaactt ttgattatga aaaaatctat gcaaagaaag gaagaagagt tgatcggctc
     4381 agattcactt ttagtgagcc agaatcaaac ttgccaacca tttcaatgca taattggtta
     4441 gaagaagatt gagaagaagc aggttgtaat tttaatacaa cctgcttctt taaaaaagta
     4501 tgggtaacac ttttggacaa taaatgcaag aagttttttt gtaagcaagt ttcagtctaa
     4561 ataatatttg aaagaatggc taatctatac aaattttaac aactatgggt aacacttttg
     4621 gacaagtcaa gaaaaaaaac aatttttctt aatttgttga tcgactaaag gtaacacttt
     4681 tggacaacac agaataaaaa gtccggtgat atcagttttg gtaggaaaca tcttaatatc
     4741 tttgtgagat tgaaggtaac atttttggac aagtcaacta tttgttaaaa gttaatatag
     4801 agtaattaga taagtttttt cttttcgtct gataaatgga taatattagt tattttattg
     4861 ctaattagtc tttcatgatg actgaaatag ctaaaataaa tatctcgttg gataattgct
     4921 gatactttaa gggatatcta aatttgctga ttgatttatt tatgttatta tgatattata
     4981 ataacataaa tgtgttacgc ccgaacctca ttttaaaaaa atgaaggggt gagacaatga
     5041 atgctattaa ttggcatgaa tttgttaact atatggagag cttactagat gatctaaaaa
     5101 gttttagtat tgctgatgca gtaaagcatg ggttaccagt tagtacaacg atgaaattac
     5161 gaggattgaa aattccagat gaaattatta agctgagaac taaaacaatt attgaaaccg
     5221 caaaagtcgt tgacaatatg aaccatgaac taaaaggcaa gaaaacaact tacgagaaag
     5281 attttgaacg ttttttaaaa tctgttattg gaaaatatct aggtaaaaaa tctttcagtg
     5341 aattgagaga tgaagagatt gtacctactc caatggttag caaaatccga aaaaacaaag
     5401 ccgaggggaa ttactatctt ggtacaatag caaaaatcat tgattatttg gaaaataaag
     5461 agcaaaagaa aggaacgaag aaaggaagat aatttttgtg ttaaatatta atggggaaga
     5521 atataccgaa atgattcaaa atcccgaacc tagaattacc gaaaaaacgt ctgattgttt
     5581 gctcttttat gaaagggggc agacaaacta atggaaaaaa acgtcaattc aacatctacc
     5641 aaagatcaat acagtattat tggagggttg cttggtgata aggataagag aacacgtcac
     5701 ggattacgca ttatgcttgc aacttttcta ggagtgcttt ttttattaac aggcttgggt
     5761 agctacattt atcaattagg aaactataat tattatctcg tgaacaatac aacacctata
     5821 ggctcttcat tggagtttgc tcgatcagga gcagagatca ctatttcaga tgtgtggaca
     5881 gatcaaaaca gagatgtaac agtagtaaaa ctcggttact cgcaaaacgc tagaaagttg
     5941 ttatctacgc aaggaaaaaa ctacaactta tatatggcaa cgaaagaaaa agatcgtcct
     6001 aaaaagcttg aaatgagcta tgggatgtta agtactgatg gggatgcttt cttattccta
     6061 aaaggtaaat tagatgaaag agcttatcaa gtttttattg caaaccaagt atcactaatt
     6121 tctggtgatg atacagctga cgatgatacc aaagtcaatg tgaatgaagc agattcagtt
     6181 acaaaagcac tttctcaata ttctatgaat gatgttaata atgaaggagt aatttctttt
     6241 gggaaaaaag caaaacctgt taatactcct gataatatca atttcagaat aaatccatat
     6301 tcagattcaa ctaatgtcta tcaaggaagc tttcttacca aagatggcga tattgattat
     6361 tcaaaagttg tagcagttac aagtaagaat aatgttgtaa gtaagttaga agatcagtta
     6421 aatgcttcaa atactaacat caagaaaatt gaagctacaa aagctgagta tctggaacgt
     6481 ttacaacaaa atcctgacga taaagattcg caagaaagta ttcgtcaact agacagtcga
     6541 atggagaccg aaattaaagc aatcaatgat acacaaaaat tgattgatca atacaaaaat
     6601 gctgacttta acaaagattc ttttggagac atgaagacga catttaagta cctaactctg
     6661 actgactaga agtaaattat tcttatttta gaggaagtga acacaaacag atggaaaata
     6721 gtaccgagtt ttttaagaat attcaaactg aatttaatca tgctctcaca ccaatgaaac
     6781 caccgaaaca taagttagtg ggacgtgatg acgaactcca tgagttgtca ctgatcttga
     6841 atagaccgga aacaccgcaa gctatcttgt taggtgaagc cggaacaggt aaaacagcac
     6901 ttgcaagtga atgggctgaa agacagcgac aagatggaaa gaaagtacaa gtatacaaat
     6961 tatcaatcgg acaattgcgt gttgggggag atgatgtcct ccaaacacgt ttagaaacat
     7021 taattccaag attgaaagaa tatgagcgaa ttttaaaatc tgaggacaaa gaaaatgaat
     7081 ttgtcctctt cattgacgag tttcataaag ttgttagctc ttttggtagt ggcaataaaa
     7141 ttgggggtga ttcgctaaaa gaaccgttag caaatgaatc acttcaattg attaccgcta
     7201 ctacaagaaa agaatatgaa aactatatca aaagagatga tgccttaggg agacggttac
     7261 aaccgttaga attgaatgaa ctaaaaagcg atgttgtcgt cgatattttg agacaatggc
     7321 taaatacatc ctctgttaaa gatgatcctc aggcttcttt taaattatcg caaaggattc
     7381 ctgatgaatt acttcaagaa atcgtacaag caaacaagct ttatcgtgag gatttgtccg
     7441 aaccggctaa atcaattgcc gtaatggagg atttgattgc aaaagatcga gtagacggaa
     7501 atgcttataa tcgagaaagt ctattgcaaa tatttggtaa gtataatatt cagctagatt
     7561 ctgattttga tatggaaaaa cttcaagagg aattaaagtc cataaaaggg caaccgttag
     7621 cagtttatac tataacaatg ttgtttaaac gtatgaagct tggatttgat cgttttaaag
     7681 gtcgaaagca accaaaagca actgctctgt ttacaggatc aacaggggtc ggtaaaactg
     7741 caatggctaa agccgtggca agaggacttt atggcgatga aaataaagtt ctcttagtta
     7801 atatgccgga ctacaaaaca aaagatgatg caatgcgttt tagacgactc ataggtactc
     7861 atgtaaggca tgatccttct gcgattattg tgtgtgatga atatgagaaa gctggtgtag
     7921 aaacactcga tgccttttta tcaattttag atgaaggtag gataagtttt actgaaagag
     7981 gatgggatga tcgagaagtt cacgacactg tttcattgtc aaatacaatt ttatttgcga
     8041 caacaaatgc aggtgcggag atgttcgatt cgttaaacag atatagctca ctatctcgtg
     8101 ttacaaacaa ggaaaattct aatgaatata gcactgaact aaaaagagaa taccgaaaag
     8161 tcgcatcagg gatcaaacaa gccttgattg gtgaaggtct aaagcctgaa gttattaacc
     8221 gatttggacg aatagttcca ttttgggctt tatccgaaca aactcttctg gaaattgctt
     8281 ataatgaaat gttgaagagt gctgaattag tacgaaaaca tttaaatata gatttacgtc
     8341 ttccacctag gaaagaaaga gtatatggtc aaaattttta tgcagacgat ctctccatgc
     8401 acttagtttt tgacatggct tcacaagagg attctaaatc agggggtgca aggaatatct
     8461 tgcatttagt tgaatctgag tttgaagaag cgattactga agcaataatt acttatccaa
     8521 acgcaaaaat attcgatgtt aagttgagtg aagccggagc gtttgaagga aaaggtgatt
     8581 ctaatgctga aattattgca aagccttccg ttgctgaaag taaagaaaac aagattgtat
     8641 tttcgattgg aggggcgtag ctatgaaatt caagaaatat ttactacaaa accttagaat
     8701 aaaacgatgg gtcgtaagag gtctagttat tggaggagta ttagcagtta ctttaggcgc
     8761 tccttttgga atgaatgatc caactcctga caatcaagat agcaaacaag aaacagttat
     8821 aaataagaac gttgcatatg cggaaagtaa accggcagaa caaggaatgt ggacactata
     8881 tgctcgtatc ctaatgggag ataaagaagt taatgatagt gccgctaaaa ctggacaaat
     8941 gaatttgtta ggacaaggtg gtatcagtgc cgatttccct tattctgaca tttctaaaca
     9001 aggtaattcg attgcagggg gtaatgcagg tactcaacta gcatctactt tagcaactta
     9061 tagttactac ggatatattg aaacagtctc aggaaatgct attgccagtc aagcatcatc
     9121 cattctagga agtattggta ggacgattgg tagttttatc ggatcaatta gtttaatcct
     9181 ttctaatatt gctgaatcca taaatgaact ccttggaaaa tttttcatga gtatgaatat
     9241 attttctctt atggggtggg gagaaggtgg atcggatgta tctaatccgg tatctaaagc
     9301 attaactagc ttgcttaaca atttgggatt aaataatgaa ttatttaaag cgatagcaag
     9361 cttatctatg ctctttttca cagcaatact aggttatcaa ggaatgaaat tattgtcgaa
     9421 agatggtgtt aactcgaagg gattatcacc agtacttgaa aaatggattg ttcgtatttt
     9481 tgtattgttt atattcttac cagtggcagg atcgctattg ggagtttata tcaacggcat
     9541 ccagtcagca aaaaaagatg gagatatacc aacaaatgtt gtttctgact acatcattaa
     9601 cacaagactt tgggcttcta ctcaaaatct tgctccatca tctgatactg gtggtgatgt
     9661 acctgacgga aagcctacat ccgaaatcaa gttcgttgat acagattatg aaccatctaa
     9721 aaaatctgca atgataagag cgatcaatac tagcagttat gccagacaaa ataatgatct
     9781 agattctaat tcagtcggta tggctctatt aaaagaatgg tcatcgaatg atactttcaa
     9841 tattaatact tatgccggtg atgttaatgt cgccgaaaat gatgcttata tgggaagagc
     9901 gcctgctgtt tggacaggct ataatttagg ggatggaaaa gaaggaagtg caattaagaa
     9961 accaaccaat ttaaatggat atatttggtc agcaaatcaa aatgtgacag acgacaatcg
    10021 caagcctgat ggaaaaggaa cagcgcataa ctttgatgct actcaacctt ggggcgttgc
    10081 taacaatgca acttttagca cacagtcggt agctttattg ctccaatcgg cacttgatac
    10141 atcgggagct aagttttatg cgtataatat cgctccttca ggaattcaag gcagtgctaa
    10201 gaatatgtca acagtaaaaa cagaatggcg tacagcatcc ttagttggtc atggagctat
    10261 gggtaagttt ggctcgtggc tagcgatgaa cgctgaatca atcgttttag cagttcttta
    10321 cttagcatgt gcttgggcga tgttcaatgt gaatatcgtg aaagcattta aacgtgaatt
    10381 tattcggatt tgggaagtag ttctaacagg atcacttgca tcaggagcag gtgtgatggc
    10441 aatttcatta ggtgttgtta caacatctct gatcggacta caattaccta tctttctgat
    10501 tacttttatt cgtgcatttg gtgatactgc tgtgggattc attcctaata cattagttgg
    10561 cgatggcgta gcaaatattg ttcgatctgc tatgatttta ggtgtaggat atcttttagt
    10621 ctttaaaaaa ggcgaaaaag taaataattt gattaatatg cttattggct taccacttga
    10681 agtagcgttt gggtttgatg aacgtgctaa gttattattt ggtaatagaa atgatgctgt
    10741 gcgagttgtg gacggcgttt ctaaagcaat caagaaaagc caaggagcta aaaatcccta
    10801 ttatgatggt ggcaacagct cagtaaaaga tatggttgca ggaggtcttg gagcagttgg
    10861 agcgcaaaaa atggctgaac gtttgaacaa tatgggagat agcaatgctg atgctaagtc
    10921 cattgctgat aaagtaattc ctgaaacacc agaaggaatg tcattcaacg gtggcggagt
    10981 tggttccaca atcaataata cctctttcaa agatttagtt cgtcaagatc aactacgtaa
    11041 taactcccaa caatatattg atcatttagg acgtatggtt gatgaaaacg gaaactttgt
    11101 cgatgaaaat ggtgaaatat taaaagatag taaatacggt aaagatgcta aaggcaactt
    11161 tattgacgaa aaagggcgtt tggtcgatga agatggaaac cttatagata ctaatggtaa
    11221 accattggaa gatagtgaag atggtaatat tggtatggat agcgaaggac gtttaattga
    11281 tgaaaaaggt cgcttagtcg atgaagatgg aaatcttgtt gacgaaaatg gacgcaggtt
    11341 gctaaatggt gattttggtc atgatagtaa cggacgttta gttgacgaaa aaggtcgttt
    11401 agttgatgaa gatggaaatc ttgttgatga gtttggtaat aaacttggta aacacagcga
    11461 tggatataat gtgaatggag atttagtcga tgaggatggg aatatcattg agacgagaga
    11521 tgcgcttgtg gcagatcgaa atagagaact cgaacaacaa cggcatacgc caattgctgt
    11581 tgcaattcct gagaatgaag aagacgagat tactttagat caaactcatc aagaactgag
    11641 gaatgaaatg agtggtgagg acgtgtcaga cagagtgcat cgggaattag gagatggagc
    11701 atctggtgaa agtcagtcaa gagagcttaa cagcaacttt gataatagtg ctattcggaa
    11761 tgacacagta cttaaagaca gagaatcgct aacaaaagaa acggataaag aacaatcaga
    11821 tgtgaagaaa aagttcattc ctactcctaa tgttaatcaa acagataaat atgaaacaaa
    11881 tattggatca ggaatgtcga aagacaatca atcaattaga gaacctgaac tgacaaataa
    11941 aaataataga acaaataatt ctaaatctac ttcagataat tcagggaaat ctaatcaatc
    12001 aaccaagaaa acatcaacag ctaaatcagc cgttgaatat ctatcaaaaa ctggtaaaaa
    12061 tgtttacacc tcagcagata aagctttagc aaaagctcca aaaggtagtc tagcagggat
    12121 aacctatgaa gctaaaaacg aagctattaa aataggtaaa ggaacggcta aggttgccaa
    12181 ggctactgct acaggagcat ccaaaactgg taaagtagtg aagaaatcta ccatgtcagt
    12241 caaggactat attgtaaaat acggtaatca aaaatcaact gaaaataagt ctgaagacga
    12301 gtaaaaagaa ggagcattga tttgctcctt ctttttactt tgatttctaa ctgaagatgt
    12361 caaggaaaat ttctatttat gcaaaaaaat tattttaaat tgtctataaa tgaattaaat
    12421 atttactgtt caaagttgta taattaaaaa gggcttatgc tggtaaagaa cagaattatt
    12481 atctaaacaa aaacttgata aaccagcatt tttagccaat aaaaaaagtg aaataattta
    12541 atggaaaatc tcttttaatc atcgaaaatt tatgttatta tgataacata aagatgtaaa
    12601 tatcgagacg tctttttctt agttagatca ttgacaagtg aacaaataag atttgtcgat
    12661 gatataatta acttattaaa aatattaaaa aggaggtttt tatatgttcg attctattaa
    12721 aaatttggtt agcggaatga cgcctgatat gaaaacttta gtacaagttg ttttgtattt
    12781 cttggcattc gttttttcgt tgaaaccagg attcactgca atgaaatttt ttggtgatgc
    12841 aaaatgggga gatggattaa aatatgttgg ggcgattatt gcaatcttta ttattcctgt
    12901 aattacaacc gttatgcttt acacaatggg tactaaaaca ggtaatgatt tgaaccaaaa
    12961 agctaatatc atatcagcac ttattccagt tgttggtatc tatctagttt caaaatttcc
    13021 aaaaaatgaa ctgttaggtt aaaagtgaat tgaacaaatt tggataatat gccgatttgt
    13081 tcaatttact ttttaccaaa aaactacgct ccaagcgtag tttagaagtg agggaagaaa
    13141 gtaaatgtaa gatggttttt gatagagaaa aaatgttagc tcacgccaac gaagtattaa
    13201 tgagcagtct gaaaggtacc gaactggcaa agataatgaa tatgaatgtt aaccagttct
    13261 atgattatcg aaatgggagt aaaaagattg aaaaagccag acttgaaacg cttattaaat
    13321 tcgaaaaagc atatgtatat atgctagata aacagaaaag aactattgac tgaaaaaagg
    13381 agttttacaa taatggcaaa attcaaagat attaccgaat ctattaatta tgtggcagaa
    13441 acagttcctg tagttgcact ctctttgaag ccacaattac tcgaagtgta caaaaaagaa
    13501 gaaaaagaag cgaaggcaaa aaaagctaaa gcaaaggtat ggaaagaatt cgatgcgttg
    13561 ctgaccaaag atttaccaaa gaaaaattat atggtaattg aagatgtaca aaagctcaac
    13621 agtgagggag ttatagatga ggatgatgct attctcgatt ctgagaagta tgtcgttcta
    13681 ttgaagtcaa gtttgaatta tgtagctgat ctaccagaaa aatttaaaga gaagctatta
    13741 gcaggtgtcc gttttatgga tagtagtggt caattattag ttattccgga tgatcctaat
    13801 gtgtttgaat cagaagttga agaagctaca gacttctata gcgcagtaga gcaattagaa
    13861 gtagctacta atggattaga acgaattgct gagaccttca actcttctga agaagttgaa
    13921 tttgaagccg tagcagaaaa tgtaccagat gaaaaagaag ctctttttgt ggatgataac
    13981 aaaccaaccg aagcagaaaa ccaagaagta agcatagaag aaacacaaat acaaacagaa
    14041 acctaccaac aaccaaaaat tgatgaaaaa cccgaatccc aaagtgacaa agaaaattat
    14101 gtttatgaag ctgaaaaaat cacatctgaa agtgatgtac cgaaaaactt agatgctgat
    14161 tttttagaaa aaaattttga acagatcatt gctgacaaat ttcaacctgt agttttagat
    14221 gagattaatg accctgtcga tttaaacgag gagatgctat ccatacctga gttgaaacca
    14281 ttgctgtttt tagctaaaga gagtatgaac gctcgcatct ctattgctaa taataaaatc
    14341 aacagtgaat taaataagac gaaggagcaa ttgatcctca aaggaaagca aatgttagct
    14401 gatgagcttt tgcggataga ggaagcaacc tcattaaatg gtcaaaatca gtttacaaat
    14461 acactatcgg ttgctaaaga gagctacgaa gcagaagcat ctaaaattga tgatttagtg
    14521 atggaaaaat ccaatatcat tcgtaaagat tatgatatgg cgaaacaggc ttatttggat
    14581 gctgaactaa agaaactaga gcaacggtat gatgctgagc atttaccaga agttaaacaa
    14641 caagaagatg aatatagaaa agcaactgaa gaaagtcttg atcaacagta ccaagaagca
    14701 attgaatcta ttaaaaacga tgcattgaaa caaagccaag aagcaaaaga agttgtggtg
    14761 gaacgaatta tcaattcatt gaaaccagaa attgaaaaat cattaacaga cgtgcaagaa
    14821 aaaactttag agattgtcga aaaaacaaag tcagaaaatg aagctgagtt ccatgataca
    14881 aaagagaaaa caacagatgt ggttgtcaaa tattttgcga acaaagaaga agttgaaaag
    14941 caggtagcta acaacacgaa agaattagaa acaaaacttg tagagcaaca aaaaactatc
    15001 gaagaatata aagatcgaat gaaagaggtc aaagatttag cagagggtta taaattaaat
    15061 agcgaaaagt tggcagaaca aagtgaagct ttaagagaag acttatctcg ttcccgaagt
    15121 gatctagctc aaatggcaga aaaaacgaaa tcattagcag ttgctacaga aaatcaatca
    15181 agttcaaaac gtgattttac aagtaaaaag atggctacta tcatttctgt cgctgcaatg
    15241 gcttgcggaa cgatcttggg atcgtcctac tttattagtc ataataatca acaagcacag
    15301 gctcaaactc aaacatctat ttcgagagtg gaaaattcga ttgggacaaa tacgaactct
    15361 gcttcaacaa atagtagcta tgaagcaaca ccaactacag agttcaaagt tgggaaagat
    15421 gttgtcatca gtattgatgg gaaaacaact aaggctgaag tgatttctat tgatggagaa
    15481 aaagcagttg tgaaaactcc agacggaaat cagtacaaaa ttcaagctca cttatctgat
    15541 aataactaag gagggctatt atgcgagaag aaaaaatagt ttatccagta attcaaaaca
    15601 atcaagaaaa catgacctct tctcagcact tacaggaagc acagctcgtg tatcaggtaa
    15661 atgaactacc acaaacgaac gagacaatga gcaagtcaat atctttaatt ggcttgctta
    15721 ttgttgcaat agtgataact gtaggtgttt accgtaagtt gaacgtgaaa ggaagtattt
    15781 ctgatggcag ataactcaaa ctatggattt aaacataact tacatcaaaa accttctgaa
    15841 acaattgtca gagttgaatg gcttgaaaag catgtcaata gcacctattc tgttacagca
    15901 aaaagattaa ttgtatcagc tatagttgtt gcagtcgttg ttcttggatc aattgtttac
    15961 ttagtttctg atacgattaa actgaaattt atttttgttc caacgttatt aatgataatt
    16021 ggatttctta ttctaattag ccagtatatg tttattgatc catctagtgg ttcattgatt
    16081 tctggttcta ttagactgtt caaatcagta gttaattcag caagagtatc tatggggaaa
    16141 aagaaaccat ttcgaggcac agagatttta aaagtgaaac aagatggaac aatcgtatat
    16201 cgagatggga gtgtagcatt aatgttcaat ctagatgggg ctacatcact aaccgctttt
    16261 ccagaagaag ttatggctca ggaatcgaaa tcaatacaat atcaaaatac cagagatcgt
    16321 tccttagctg aaatcaaaat cacttcatct caacctcaga atacggaaag acaaactcga
    16381 aatatgaaaa tacaaaaacg aaatgcaagg agtaacaaag cagtctttga cataatagat
    16441 cagcaagaac gatttgtatc agaatatatt gatggtgtga aaacaacagt aatccaatat
    16501 cttatcttga aatctcaatc taagatggta ttggatgaag gtgtggaacg tttagaaaac
    16561 tatacgagta gaggacttta ttatagtgtc actcagttgt cagctaaaca aacaaaagaa
    16621 atattatctg atatttatgc actgaaatag aggtgagaga ttaaatggaa attatgggta
    16681 gatcacaact attaaatttc aaaaaaaaga gaaaaactaa aaaagaacaa aaaactagaa
    16741 attcaaaggt agtgaataat acctttgtta gtgatttaac atctttagtt ggttatcaat
    16801 ttacaccatc ttacattagg acaggtaagc ggtggggaac aattgtgaaa ttagtgaata
    16861 cttatggaat gaatagaaat tatggatttg gttggatggt taaagctatt cctgaagtga
    16921 gagtagaagg ggtaaaagcc tatctaattg aagcagataa gccagtgtca caaaaagatc
    16981 aacaagaaat aatgcacgag aatgttgggg gatcaacgaa tagttatgaa aataatttag
    17041 aaggaaaaaa ttcagatgct gaaattagca aaactgttat gcggattatg gatttgaata
    17101 cagcatcttt actagacagc atggcaaata aaattattga ttggaagcta gaaatcctat
    17161 tagtatccga ttctcctaat aaaatcagcg aacagctaat taaactccaa cggttgtatg
    17221 atgaaaaaat gtatggatta aagcttatgt catatggagg agatcaacgt gatctgtttg
    17281 atagactttt aagtgaacca atcgggaatg tctatgagta tacgtctatg agttcggatt
    17341 ttgcaggaaa tgatcatgca attcgcaaag gtttagatga tgcgaatgga tgggctatcg
    17401 gcactatgtc tactagctac gcaagtggtg tagcttttat ggcactggat gattctttta
    17461 caagtaaagt tttagtggca tcacacaaaa acgctacaat taaaggctat gatgaaaaaa
    17521 tctcagcatc atcactttgg gggcaattga ttgctaataa tgcaatggca aatcataaac
    17581 gaacttttca tattgtctta aataaatttg attactttgg tgatccaact ggtagaacat
    17641 ttgttgccaa accttcgtta aacagtgtaa tagaaaaggt taatttggct gaagaaggtc
    17701 ttaactcttt ggagcttttt ggtaatcaaa aggacattgg tgatttatat agacggaatc
    17761 tcgataaact aactcagatt ttttatttgt tagcaggcag aacattagat tctgcaacta
    17821 gagttttatt gaaaaaagaa ttaggtaact tttatataag tcagaaactt tgggatatta
    17881 attatgaaga acgttcaaaa cttttggtga acagtagtga tacaatgcca gttcttgggg
    17941 attttattag ctatttgact aatgctgaaa caaaagccaa aaaatctggt actgaaaaag
    18001 aagtcgatcg tattattgta ttaaaagaca cattgagaac agcattagac agcttctcta
    18061 ggatgtttaa tcaaagaacg acactgaaag aaatcggtaa aagtgacaaa ttacagtttt
    18121 actataactt aggtgatcta agagcagaaa ccaatgttat ggaagctcaa tttttaaata
    18181 cctttgattt catcacatca caagcaaaaa aagatgatat tgttatgatt cacggcttcg
    18241 ataagttatc tattgaaacc gttgggctaa ttaaaaaaag attaacaatg cttgaagaag
    18301 atggaattcg tcttgccttt ctatttgata caatcggttc aggagaagac aatgaataca
    18361 aagaagatat tgaaacagct gatatattca atacagatgg aaaaatttac caaagttttg
    18421 aaagtgattt taattacact atcattggaa agatgaccag tggagagtta atgaagtatg
    18481 aaaaaaaagt tgctcctgct agaaaaggag aagatgatca aaaactttct gttgatttga
    18541 gacagtattt gacaacagga agaagtaata aatttcagat caggagacca gtggatctga
    18601 ctaataattt tgttattgga gagtttattc tttaagtttt atctttgatt ttgagtgtat
    18661 aaggaaagga taagaaaaaa catgtatatt tgagactaaa aacagtctta gagaacatgg
    18721 tacgttttgt gaaaagagaa ctatagaaat ttcataaagt gaaaccttac tgagtgaaat
    18781 aattatagtg gaggttaaat aatgaaacca aacataaaaa ttttagatcg aatatttcta
    18841 ggtagagaca cagaagtaat cctaattcaa catgaagaag gatttgaagt tagtataggt
    18901 attcagaaac ttcaaaaacc tcattattgt aatcagttgt ataaaaactt tactgatgaa
    18961 gaaaaagcga gagtttt
//
LOCUS       DAPBBV010000050        18396 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.050, whole genome shotgun sequence.
ACCESSION   DAPBBV010000050 DAPBBV010000000
VERSION     DAPBBV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.050"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..146)
                     /locus_tag="RD486_002273"
     CDS             complement(<1..146)
                     /locus_tag="RD486_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7663991.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMA"
     gene            complement(143..796)
                     /locus_tag="RD486_002274"
     CDS             complement(143..796)
                     /locus_tag="RD486_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7663992.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1084..2017
                     /locus_tag="RD486_002275"
                     /pseudo
     CDS             1084..2017
                     /locus_tag="RD486_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1925..2641)
                     /locus_tag="RD486_002276"
     CDS             complement(1925..2641)
                     /locus_tag="RD486_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDT7663993.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(2765..2950)
                     /locus_tag="RD486_002277"
     CDS             complement(2765..2950)
                     /locus_tag="RD486_002277"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7663994.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            3177..4450
                     /locus_tag="RD486_002278"
                     /pseudo
     CDS             3177..4450
                     /locus_tag="RD486_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4557..5588)
                     /locus_tag="RD486_002279"
     CDS             complement(4557..5588)
                     /locus_tag="RD486_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7663995.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(5595..6425)
                     /locus_tag="RD486_002280"
     CDS             complement(5595..6425)
                     /locus_tag="RD486_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7663996.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(6422..7237)
                     /locus_tag="RD486_002281"
     CDS             complement(6422..7237)
                     /locus_tag="RD486_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7663997.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(7234..8058)
                     /locus_tag="RD486_002282"
     CDS             complement(7234..8058)
                     /locus_tag="RD486_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HDT7663998.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8048..9148)
                     /locus_tag="RD486_002283"
     CDS             complement(8048..9148)
                     /locus_tag="RD486_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7663999.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            9326..10111
                     /locus_tag="RD486_002284"
     CDS             9326..10111
                     /locus_tag="RD486_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HDT7664000.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10144..10527
                     /locus_tag="RD486_002285"
     CDS             10144..10527
                     /locus_tag="RD486_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDT7664001.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            10603..10734
                     /locus_tag="RD486_002286"
     CDS             10603..10734
                     /locus_tag="RD486_002286"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7664002.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            10703..10939
                     /locus_tag="RD486_002287"
     CDS             10703..10939
                     /locus_tag="RD486_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7664003.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11017..11988)
                     /locus_tag="RD486_002288"
     CDS             complement(11017..11988)
                     /locus_tag="RD486_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDT7664004.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            12640..14262
                     /locus_tag="RD486_002289"
     CDS             12640..14262
                     /locus_tag="RD486_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HDT7664005.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVSQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYSFEEKIP
                     HFSTFGKNYVRQFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANANKHKFT
                     KEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVK
                     GEREKQFAYSAHTSCDDNGFILSTIITPGNIHDSQVAFQLVKQSKRLFPEINCVVADA
                     GYKTPKFVHFLTHLNLRPCLPYSRPKGKKGLLSKNEFLYDEYFDCYICPQDQMLAFST
                     VTRERYREYKSNPKECVNCPLLNQCTKSKNHQRVITRHVWGDLMDEVEHLRLTDLNKS
                     IYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKE
                     PLFFCSKIRNEVDKKLFQARVTSLEQLLSTVCDVGDISFSIRNQLRFKRSLPVSGNIN
                     VYFTKARFKRLIAITVSSIVMFLWLFRMGVIP"
     gene            complement(14548..15924)
                     /locus_tag="RD486_002290"
     CDS             complement(14548..15924)
                     /locus_tag="RD486_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7664006.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(15924..16580)
                     /locus_tag="RD486_002291"
     CDS             complement(15924..16580)
                     /locus_tag="RD486_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7664007.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(16590..17867)
                     /locus_tag="RD486_002292"
     CDS             complement(16590..17867)
                     /locus_tag="RD486_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7664008.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(17886..18047)
                     /locus_tag="RD486_002293"
     CDS             complement(17886..18047)
                     /locus_tag="RD486_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDT7664009.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            18117..>18396
                     /locus_tag="RD486_002294"
     CDS             18117..>18396
                     /locus_tag="RD486_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7664010.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPRAEIIREYELTPSSFDKW
                     MKQAQSTGSFKERDNLTPEQAELIALRKKNKQLEMENDILKQAALIFGR"
BASE COUNT         5648 a         3889 c         3110 g         5749 t
ORIGIN      
        1 gccatattat gaatcttttc ttttctcgtc tccaaatatg ttttaggaaa gataaaaaaa
       61 attaatgaat gaactaatat aattattatt ccaagaacag aaaatatttg tatgaacatt
      121 tttggaaata tctttaattt tttcattttc tctccaattt atatcctaca tttcttatag
      181 tagttataca gtctaattgt aatttttttc taagttcttt tatatataca tctattactc
      241 gatcataagg agtttcttcg ctatctttcc atacataatc aataatttgc attcttgtta
      301 acacttgtcc attattatcc aataaacatt ttaatacttc tagttctttt gcatttacat
      361 ctatttcttc accatttatt ttagctgtat agctattaaa attaaccgat agatccttat
      421 attcaaactt ctctaaatgt ccataattct tcttaattaa agaatctatt ctagctttta
      481 agaccggcaa tgaaaatggc ttttctacat atccgtctac taaattagta aatgcatcaa
      541 ttttatattc ttcatcacta aatgcagtca agattagaat tggtaaattg cttttctttc
      601 taatttcttt caacacttct aaaccattta taaaaggtat ctgaatgtct aagataacca
      661 aatttatatc gctattaaat tttgacaagg cttctcttcc atctttagct tgaataacag
      721 tatatccaaa ttctgaaaga tattcactta ttccctctct tatcatatta tcatcttcaa
      781 cagttaatat tttcatatat acctccactt aagcctatac actagatatt atacagcata
      841 ttatggctct ataatatcta gtgttggtga cgccttctgt tgccaatact ttttcttttt
      901 tttaataaat gcaaacagac accttgaaat cctttagaaa aaaggcttct ataatatttt
      961 gtgttgttgg aaaatcgaag gcgattttct actaacactt tttcttcgtt tcaactcaaa
     1021 aagagactca cttttggtaa aatttagtcg accaaaacat caccctacca aaggagtcgc
     1081 tctatggata atcatactag aaaattactc ggattaacag ataaacattt attttttgat
     1141 gaagaatggc tgattgaaaa agaatataaa ggcgttcaag cgcagtttat taaagggaga
     1201 ttggatgact caccttccca ttgtgaacac tgtggatcga ttcgtattat ccgcaacggt
     1261 tcctatacga cacgtactca gatgttgaaa gtcaaagaaa agttgactat tttagaatta
     1321 aaacgtaccc gttttctatg ctatgattgt gggcagacct tttctgcgaa aacggactta
     1381 gttgatgaac atcatcaact aacaaaggaa ctgaagcagg cgattctcat agaactgtac
     1441 gaaaatcaat cacgtaaact aatcgctaag aagtacttcg tctcggatgg gacggtgaca
     1501 cggatcttgc gtgaagcaac gaagcattac cagccacgta tgaacttcct tccgacggtg
     1561 ttgtgtatgg atgagttcaa atcaatgaag tctgtttcta gttccatgag ttttatttgt
     1621 gttgatggga caacccatca gctatttacg atccttgaag atcgcagact ttacaaacta
     1681 actcaatact tcctgcactt tcctagaaaa gcccgtttaa aggtcaagta cctagaatgc
     1741 cagctattgt cagctgctta aaacggtctt tccaaatgcg gagatcgtaa ctgatcgctt
     1801 tcatattgtc caacatatca atcgcagctt caatcaattg cgtatccaga tcatgaatcg
     1861 ttttcgagcc tcgcactctg aaaatcagaa gaagtaccgt cggctcaagc gatattggaa
     1921 actcttactc aaagattcca cgacattgga gccgctcaaa cggcattatc atcgactgtt
     1981 taaacgacca attagtcaaa cagaaatcgt cgatgaaccg ttgtgcacaa tggtgtcctg
     2041 aacgtacagc gacaccttcc atatccagag cagtcgccac atcacgggga tggatgccat
     2101 ccaaattaaa agcaaccacg ccagtatgat gttcaggatc ttgcggtccg taaatggtga
     2161 taccgccgat cgcttgtaat ttaggtaaaa cgtaggcaac cagttcttgc tcataacgat
     2221 gaatattctc cataccaatc tcattcaagt aatcgattgc tcctgcaatg ttcggagtac
     2281 cagcttcaaa tttccatggc agctctttcc atgaactatc gtaaagattg acaaaatcta
     2341 tcatttcacc gccgaattcg actggctcca tttgttctaa caattgacgt ttgccatata
     2401 atacaccgat tcctgtcggc ccgcacattt tatgcccgct aaaggcgaaa aaatctgcat
     2461 ccaacgcttg tacatcaact gtcatatgcg gtgctgcttg ggcaccgact ggactatcct
     2521 caactacaac agcctgttca accctcagcc gtttcaagca caacaaataa ccttctggat
     2581 ctggtttgcc gacctgaaga tcatcgatcg tcacaaagga atcaattttt tccttaatca
     2641 tcggatgtgc ttcaaaaaaa tagtctagct cccgcagttc agaattgaga ctactccgat
     2701 tttccagtgc tgctgatccg ctgctcaaaa tgttcagcat ccactggtct cccaaccgct
     2761 tgacttatcc cttcataaaa ggacagttct gctgccgtcc caacaccttg ttgatagtct
     2821 gcaaaaggaa ttttatagcc gaactgctcc agtaaatagg cttcagtaaa tagtgatgaa
     2881 tactctcgta aaacatccat tcactgtcaa tcatcgtccc atcaaaatca aaaataagtg
     2941 ctttggtcat cttctttccc ccttacccaa aacaagcaaa agctgtgtcc tgctctctct
     3001 acagtatcag cataaaaact gccgtctgaa aagtcaaagg tgaaagaaat gtggcgctat
     3061 aatttctagg actgatagta aatcattcta tcagtccttt tgagcataaa aaaacaaaac
     3121 atacagaagc tccgttagaa ttgaatcacc acaacacaat caaaggagcg ttctgtatgc
     3181 ctgatcttca tcttatcaaa ctattactag gaatcaaaga tggaaacatt caaatcactc
     3241 atgtcgagaa gaaaaaaata cattcaatca acagtatcgt tgtttctgcc acgctcatta
     3301 aaacgattca gccctgtcct cagtgtaaac aggtgaatca acatgggctg atcgttaaga
     3361 acggaaagaa aaaatcgctg gtccttctca ataagtgtgc gaatcaacgg acttatcttg
     3421 ctttggcaaa gcaacggtac ctctgtcgtg gctgtcacac ctattttacg gcgaatacct
     3481 acattgttga aaaaaactgt tttatcgcca aacaagtaca ttataaaata ttggaggaat
     3541 tgactgaaaa acaagcaatg acgacgattt ctaaacattg cggcgtttct tggtcaaccg
     3601 tttcgcgaac actcgcttct ctgctcccca tgacaaacgt gaaaataaat tggttgcctc
     3661 gctgttcatt ggtagatgaa tttcgttcat tgaaaaatca agtcggtccc tattcttttt
     3721 cttgtatgga tggcgatact gggaaattac tggatattct tccttcacgt aagaagaaag
     3781 atctcatttc ttattttatg caatttgaac gacgtgcacg tttaaacgta aaaatactcg
     3841 taacagatat gaacgcctct tatgctttgc tgataaaaga gtgctttcct catgccaaac
     3901 tcgttgtgga tcgctttcac atcgtcaagc acctcattcg cagttttaag gatatttgac
     3961 tatgagtcat gaaaagcttc gaccgaaacg atccaataca agccaaacac tatcgacaag
     4021 tgaaggcttt atctcgactt ctgatcaaac gacaggacac gcttgtttat gataaatgga
     4081 caaaatggcg taattttggt tgggcctatt taaccgaaag tgaagtcgta gaacgtctac
     4141 tttctacttc tgatgaacta cgaatagctt atgcttacta tcaagaaatt cttcaagctt
     4201 tttatgacaa agaagcggac atcttctttc agcttgtaaa aacaatgccc aagtcggttc
     4261 caagagaact gcatcatata aaaaaagcgt ttataaacta tgaatccggc attcgtttag
     4321 ccttagagtt gccttactca aatggcaaaa tagaaaatct gcatacccac atcaaagcat
     4381 tgaaacgaat agcttacggg ttaggatgag aaccagaatt ttcttaatca atcatctgat
     4441 cacttattaa acataaaaaa acatctaaag cagaaaatca attctacctt agatgttctt
     4501 atatcactct atcagtccta tttgacaaag agccagaaat gtttgccgac tatacactag
     4561 ctttgttgtg caaaatgctg agtatcaatt tccacaggga ttgctagaat atctttcagc
     4621 tgaatgtata aggcatcgct aattttctct tcccgatcgt tcaaccgatc cactaaaatt
     4681 tctttgccct ccagcgtttg aaaaacatac cgttgaatgt tgcctaaaat aaatgattcc
     4741 ttccatagaa ccggaatctt aaccccctga ggaaccggtt caaattgaat cagctccggt
     4801 cttaaataat aaatgcagcg attgccctta gcggaaaact cgtgggtata ctgattcagc
     4861 tcataccatt cgaaacgatt atagttgccg ataaattccg caacaaatcg gctctgagga
     4921 ttctgataca attccttcga ggtggaaacc tgagccaccc gcccagcttc catcacaaaa
     4981 atccgatcac tgattcgcat cgcctcttct tggtcatgag tcacaaaaat catcgtcatc
     5041 cctagcgatt gctggatagc gcgcaaatcc cgctgcagct gttttctaat tcgggcatcc
     5101 aaagcactta atggctcatc cagcagcagg actttcggtt cagtgaccaa tgagcgagcc
     5161 agtgccaccc gttgtcgttg accgccagaa agaaactgga catttttatc tgcctgctcc
     5221 gtcatatcca ccaatgatag catctcaaaa accttttcct gaatcacctc aggactcagc
     5281 ttctttacct tcaaaccaaa ggctacattt tcaaaaacag tcatagttgg aaacaatgca
     5341 tactgttgaa aaacaaagcc gatattgcga tccttcgtag gcttatcggc aatattctca
     5401 ttgtccagca caatctcacc gctctttggt tgttccaatc ccgtgataca gcgcagcaac
     5461 gtagactttc cgcacccgct gggacctagt aaagtaacca gctcaccctt ttcaatctga
     5521 atttcatcaa tagctaaaat ctgtttttca tcaaaaaaca gattgagatc atgtatttct
     5581 aaaaacattt tccgtcacaa ctcctttaag ggcttctttt tcgactgctt ctcttccctc
     5641 gtctgcttaa gggacagctg ttgcttttgt cgataagtca gcataaaggt agttaaagca
     5701 attcccacca taaacagcaa atacaaaacc atcacagcgc tagccaaatg gccgttttcg
     5761 ttcatccgcc gcagcatata gatgcgtacc gtctgaaatc gaccgccaat caacaggttc
     5821 gtcagcatgt actccccaaa aaccgaagaa aaaatcatca gagaaactag ggtcacaccg
     5881 atacggatgt ttggaaacag cacctggata ataatcgtag acatcggggc gcccaaggtt
     5941 tctgctgcat ccactaattc cttcagatta attaagcgca tctggttgtt aagactaaga
     6001 tagacaatcg gcaacgccgt aataaacaat gcacctacca acactacaaa cattgggata
     6061 ccagtttcag catacgttcg aagcaaagcc gttaccaaaa tcactcctgg taaagcatac
     6121 ggcagcagga gcagcttttc cagccaacga ttcaaacgag ggaaatacaa atgaatccaa
     6181 ataatggtgg gaatcatcaa caacagaatc gtcaccaaga ccacacctgc taataaaagt
     6241 gagcgaccca ccgcagcaat aaattccctg tccgtcagca gctgttggaa ccattgcaag
     6301 gtaaaatcac taggtaaaag cgattttgac catttagtgg agctggcata caaaatcgtt
     6361 ccaataatcg gcagcaagta atacaggaca aagcagaaca aaatcggttt tattaacttt
     6421 ttcacgtctg caccaccttg cctttctttt gaataatcaa cattgccgtt accagcagga
     6481 cacctaaagc gactgccaac gcactgccta aattaggctt ggcgaacaca tctcccgaca
     6541 ctaaagccgc aattcgaatc gttaaaagat ttacattact gctggtcagg gcatacgctg
     6601 tttcataggt ccccatgcca ttagcaaata agatgacaaa ggtgctggca atcgatggtc
     6661 gcaaaaaagg caaagccacc ttgaaccaag catacgctga tgaagcgccc agcaattgtg
     6721 cggactccag ccattccttt ttcacttcct tcatgctggg atacaaaaac aagaccccta
     6781 acggaatttg gaaataggta tacgtgatgg tcaatcccca ccaagaatac aaattgaagt
     6841 ccgctagaaa tggcaaaatc attttcagca cacctacatt ccccaacaaa ataataaaag
     6901 agaatgccag cggaatccca gcaaaattag ctgccaaatt ggaaacaaag gtgattttct
     6961 cctgcaattt agtcgataga ttcattaagc ataaacataa aataaacgtc ccgattaacc
     7021 caatcacact ggagctgaca gcaatcagta cgctgttaac aaaggcctgt gtgtaatatt
     7081 tgttgctgaa aatatcactg taattggcca atgtccactg gttagttaaa tcactgtgca
     7141 agctgcacag aaccataaaa agcagcggca gcagtaaaaa tgcacagaag ataaaggagg
     7201 caggaaccag aaccaagcgt tttttcatct ctttcatccc ctcatcaatt cttgaatgtc
     7261 ctgcattttc tctgacggtg caattcctaa taaccagcaa aacaatggag ccgccagcag
     7321 ctgtggtaca gtttgttcct tcagcttttg gcgtttattt gaaatcaaat aaaaaggaac
     7381 ttcacgatgt gcagccaagc tgccgccatg cagtccgtgc gcatccatcc cgtgatccgc
     7441 agtcaccacg acttgataac ctttttgcag ccattcagga aggtaaatag ccaataatct
     7501 gtccgcctga ttaaccgctg ctgcatattc atgagaatcg gcggtaaatt tgtgaccgac
     7561 atcatcaata ttcatcgaat gtacgaccaa aaagtctggc tgatactgat tcactaaata
     7621 atgggcatcc gcaaataaat gcgaatcagg gtaagtgtcc tcactataaa agatgccatg
     7681 ctgaatcagt cgctcctcct gatgctggat gcgatcaacc aaacgattat agggggcttg
     7741 attgtacaac tcgctgtacc agtggtaagc ggcggctcct gtttttccgc cagcttcctt
     7801 aactaattca aacagcgacc actctttgga tcgctgagca tggtaattac tatagatgcc
     7861 attttcatag gctggaacgc cggtcatcag tacttcgtat aacggacgtg aattgctggg
     7921 cagctcactt tttaccttca ataagcttgc ttgctggtgc tcaactaaat gattcatgaa
     7981 cccaagctgg gcgacggctg tgtcgtagcg acagccgtct agtataacta caatcagttt
     8041 gtcaagtcta ctttgcatag gtcagtacct ccgcctgcca aagctctgga agctctacag
     8101 aggtcttgtt ccaagcttca ttgtcttcaa ctggcaccgc cgcttcataa gcatcctccg
     8161 gcagtaattt ttcagctact tctttaggca gctctacctt gcgaataggt cgcgcatagc
     8221 cctttgccaa attgatttgc ccttcatcag ataaaatata ttcccgtgct agctttgccg
     8281 cattgggatg aggggcattt ttattgatta aggttgtata cccgctaatg atggagccgt
     8341 ctgttggcac agttacctca aaacgctcgg agtcaatttg gtcacgataa tttagtccat
     8401 tgaagtccca aacaactgcc acatcgattt cacctttttc aagatttgct acgctggcat
     8461 caacggtgga caaacggcct ttttctgcca tttttttgta gtaattcaga cctggctgaa
     8521 tatccttttc gtcacctccg ttggcaatcg ccgcagccaa tacagcaaat tgtgcttggt
     8581 tggcaatcgt cacatccccc acgctaactt gatagtcacc ctcttgcagc tccttccagc
     8641 tagtcggtgc ttgcttcaca ttctctttat cggtgataaa ggaaatggtt cccgtatagc
     8701 ttaacaacca atccccatca tcatcctttg cccaatccgg aatttcctcc caatagttgg
     8761 tcttataagg taaggttaac tctttgcttt cagccaacgg accgaagctg ataccgacat
     8821 caccaatatc ggcggttcca ttttttcctt ctgattcaaa cttagccaat tcttctgcac
     8881 tggacatatc cgtatccacg tgacttaagc cgtattcttt ttcaaggtcg ttccaagtgc
     8941 ctacccaatt tgcccaagta tccggcattc ccaagctggc aatctctcct tcttccttgg
     9001 ctttttctat aatcgtatct aaagagtcgt ctgccgcagc cgattgcttc gttgcttcac
     9061 ctgagccgca gcctgtcagc aggatactta ctgttgctgc acaaaataaa ccgatagtca
     9121 tgttacgaat tttttcattc attttcattc attcttctcc cctttcgata attccattct
     9181 aacaaagctt tgtaatgaga gaatcagttt cttgaaaagg tttcatgaac aatgtaaagg
     9241 ttgtatatgg tttgtaaatt tcgacgaatt cccgttaacc ttctaaagct tttgcggtat
     9301 gatagtagaa aaaaggaggc tccctatgca gtattatgat cagcatctcc acacgtattt
     9361 ttcctttgat tcagaggaaa aatttgaaaa ctatttagcc tatcagccgg agtttttcgt
     9421 ttctacggat cactttgatt taaacaatcc atctaccgga aaagatgaca ttccggatta
     9481 tccagcctat ataaacaaac tggactcttt aaaagaaacc tattccacca aatttctgcg
     9541 aggtatcgag attggcgttg ttccaggaca agaagagcgg atcgtggatt acctcgctca
     9601 gcatccttat gatttaaagc tggtaagtat tcatcaaaat ggccgctttg attatatgga
     9661 cgatgtggtt ttaaccaaag atcccattca aactaccaag gaatattttg atcagatgtt
     9721 gcaggtcttg acggattttc cagaaggaga tattttgact cactttgatt atggattacg
     9781 ccgcttcacc ttcacagcgg aagaattcgc ggagcatttt gaggctcagc tgctaacgat
     9841 tttcaaaaag gttgttgaac gagaattggc gatggagtta aatgccaaga gcttcttgaa
     9901 atacggcaac gaagaccttt accgttatgc cgttcctttg tatcaaagtg tcggcggaaa
     9961 gctctttacc ttaggctcgg atgctcatgt tgccgaagat tatcagctgg gctttaaaaa
    10021 aatgagtcag ctgttggcag actgtcaggt agaaaagttg ctagtcattc aaggaaaaga
    10081 acgccgcctg acgccgctgc cgattttgtg attcctatat aatagaagaa agtggtgaaa
    10141 aaaatgagca acctgtggga ctacaatcaa gaggcaccca tccattattt aattgcgcga
    10201 cattgggatg cgttgaaaat tgaggcggtt tgccgatcct tgttagcagc cgttccaaaa
    10261 caacaactgg aaaatttttt ggtggctgac agcttgcagc gggaaaaagt tcaggcttat
    10321 tttgcagcct ttaaagatca gcctttggaa tatttgcatg cgcagtttca tcttttttat
    10381 caagtagccg ccccagatga ctacaacgat ttacgaggac agctgcaatt gacctttcaa
    10441 gcggatgaaa ccgcctatac cgttttattg ggaatggctc gccttggtga tcaggcgaag
    10501 gtcgagtggc ggattttcga tatttgatgg caggatcaag gcgtttcagt tgcaaacctt
    10561 cctctctttc aattagaaaa accgcagcag gaagaagttt gtgtgctggt caccgatgct
    10621 ggtgaaattc gtctccgctt atttcctgac caagctcccc tggctgtagc caactggcgc
    10681 tccctagctg agcaaggcgt ttatgacaac acacctttcg gctcgtgtca ttaaggaatt
    10741 tgttattcaa ggtggcgctt tggatggttc tggtgatgaa gctgtttcca gctatgaggg
    10801 ctttttcgct gatgaagtgc atcgcggact ttatcatttt aatggcgcct tggccttagg
    10861 ggaccacggc ccccacacca acggcaacca gttttttatt gtgcaaaaca caaaggcgca
    10921 ggctgacctg ctaatgtaaa gcaagcatac ttggagcttg gaggactacc ggagctggat
    10981 ggtcgttata ctgtttttgg acaggtatac caagggttag aaatcgtagc agcgatcgca
    11041 gctcagccga caaacagtga agatgtaccg attgagccag tgttcattcg acaaattaac
    11101 ttcgaaaaaa catcgtaaaa agacactcac tgacttcagc aaaagctcta ttcttgagct
    11161 ggctgcagct agtgagtgtc tttcatttat ccataagata aagcttggat tcaataaata
    11221 aataaatgtt ttggttaaag ctgtgaccag caaatgagga accgtgcgag ccagttgatc
    11281 tgccaatgca aacatttctt taggtgaagg cgctggcgtg tctgccaacg gatactccag
    11341 tcccaatgct tggtaaccgt gcataccata gcagtggtac ggtagtaatt ctaacggtac
    11401 gaaccgatca agatctgcca caaaacaagc aatcgtcagc agctcggtca ggttcatatt
    11461 gatacctgga accacaggaa ctcgaattcg cacttcgcag ttaggatact caattaaaaa
    11521 gcgacgaata ttcttcaaaa tttgttggtt atctaagccg gtccattgtt tgtggagctt
    11581 gctggtaaac atttttacat ccacaaacaa tgtatccaca tagggagcta ccttttggat
    11641 ttcattataa gcaccacaaa agctggtttc cagtacggta ttgattccaa tgtatttcga
    11701 tttttgcaaa atttctttag caaaatccgc ctgaaccagt gcctcgcctc cgctaatggt
    11761 cactccgcca tccgagtgaa agtaaaaaac agcatccttc tcaatctcat ccattacctc
    11821 ttcagcggtc atggtctggc caaatccttt ttcaatctgc ttgctttgtg attcgggaat
    11881 cgaacaccag gcacagcgta atgggcagcc ctttaaataa acaacggtcc gtaaaccagc
    11941 accatcatgt agagaaccct gttctattct taatactgtt ccttccatat agatttttga
    12001 attacacact agtttaaact aaaacacaca aggaaaaact taccatttaa tcataaaatt
    12061 agctcatata aatatactag gatgtaaaat agactggtca aaatctggtc aaaaaagagg
    12121 actaatacag gtagtcctct tttttgttat tttaatattc taaatcattt tttattggtt
    12181 tattccctta ttcgatgtag actcaaatca ctatatcact agatatcaaa cggcgtcata
    12241 cggaatcaaa aacatcaaat ttgacctgtt aaatggtcat tgaataacat tcaaaatcaa
    12301 taaaacggag tcagacacgg agtcaaaaac gctgagagta aaaaatatat acagccttgt
    12361 aggtaaagta ccacagggct gtatattttt tatttcagat taccttaaat gattccattt
    12421 actttttatc tcattttttc ctactagtta gtatcaaata ctctcctatt ttctcaataa
    12481 actatttttg gatacatggt atctgaaaca gctaaaacct tgtcattaca gcaaaaaatc
    12541 acgttatcca gactgtagac aaagtccatt ttatggatga tgtctacagt cttttctttt
    12601 ataatagatt tatgaaaacg aatgcaagga gtgatagcta tgatgtctaa aaacaatacg
    12661 aatggtagaa atcaatttgc gatgcttacg attgatgatc tagtttctca agatcatctc
    12721 gttcgaaaga ttgatgccgc gcttgatttt gaatttattt atccaatcgt cgaagccact
    12781 tactccgatt taggtcgccc aagtatcgat ccagtgattc tgatcaaatt ggtgtttatt
    12841 cagtatttat tcggtatccg ttccatgcga caaaccatta aggaagtcga taccaatgtc
    12901 gcttaccgct ggtttttagg ctactccttc gaggagaaaa tcccccattt ctcaactttt
    12961 ggaaagaatt atgttcgcca atttagagaa acgacggtgt ttgaggatat ttttgcctat
    13021 attttagaac aagcagttaa agcaggtttt gtaacagagg ataatttgta tctggattct
    13081 acccacatca aagctaacgc caataaacat aagtttacga aagaaatgac ccatgatgaa
    13141 gcgaaagcct atcaggatga attagaagat gagatcaatc gtcaacgaat agaggctgga
    13201 aaacgccctt ttactttgga cttagaaaag gaagtgaagc tgaaagaaag aaaaataagt
    13261 aaagctgatc cggaaagcgg ctactacgtc aaaggcgaac gagaaaaaca atttgcttat
    13321 tctgcccata cttcatgcga cgacaatgga tttattctta gcacaatcat cactcctgga
    13381 aatattcatg acagtcaagt cgcctttcag ctcgtcaaac aatcgaagag actttttcct
    13441 gaaatcaatt gtgttgtcgc tgatgctggg tataagacac ctaagtttgt tcactttttg
    13501 actcatttga accttcgacc ttgtttgcct tattcaaggc ccaaagggaa aaaggggcta
    13561 ttatcaaaaa atgagtttct ctatgacgag tattttgatt gttatatttg tccgcaagat
    13621 caaatgctcg ctttttcaac ggttactcga gaaaggtacc gagaatacaa atccaatcca
    13681 aaagaatgtg tgaactgtcc tctgctaaac caatgtacca aaagtaaaaa tcatcaacga
    13741 gtcatcacga gacatgtttg gggagatctg atggatgaag tggaacatct tcgcctaaca
    13801 gatctgaata aatcaattta caaaaaacgg aaacaaacga ttgaacgaat atttgcggat
    13861 gcaaaagaaa agcatgggat gcgttggacc aagtatcgag gcttggaaaa agtcgcgacg
    13921 catacgatgc tagtgtttgc tgcaatgaat ttaaagaaat tagccacctg gctatggaaa
    13981 ggcaaggagc ctttattttt ttgttcaaaa attcgaaacg aagtagataa aaagctgttc
    14041 caagctcgag ttacgagttt ggaacagctt ttgtctacag tctgcgatgt cggagacatc
    14101 tcgttttcta ttaggaatca actcaggttc aaaagaagcc tcccggtctc tgggaacatc
    14161 aatgtttact ttaccaaagc tcgttttaag cgtcttattg ccataaccgt ttcgtcgatt
    14221 gtcatgtttc tttggctctt tagaatgggc gtcataccct aaatggttat tcaattctcc
    14281 ttgaagcatt ttttcaaata agggaccaaa cacatctttt aaaacatctt gcatatcctc
    14341 tacagattcg ggttgataag tattcaaaat ggattcagct aacttctcag catcaggatt
    14401 tcctttcttt ctagccatcg tgtaatcacc tcttgatctt attttagaaa aataaaaacc
    14461 gtgaagcaac cacccgccta ggattgatgg ttacttacac ggtttatatt acactctcat
    14521 ttttggtgct aaaaagcacc gaaaatttta attattgtca attaataatt cttttggatt
    14581 ccttcttaat atattgaatg aagaaataat caatgataca agaagtacta aactcataaa
    14641 tataactaca taaatcatga atttaggtaa tacattgata tctaaacttg ataatgtctt
    14701 gttaaatcct tcagcttctg ccccaccacc taattggcta gatgcagatt gtttagctat
    14761 ttgtttagct atatcaccag taaccttatt caatatatta ttcccaagct tgtcagctgt
    14821 atattgagct aagaaatagg aaccaacgaa tgcggggatt gatataaata ccatctcaat
    14881 taggaattga ccaaaaattt ctaattttga tatacctaat gatagtaata ctgctatttc
    14941 tttctttcta gcattcatcc ataagaataa taataatgaa actacaactc ctgcaaatat
    15001 taatgagcca aaaaataatt tatttgaaat tgagtaaata cctgatatag attgttgtaa
    15061 tgcagggtaa tttgatgaac ttttaatcaa attatattct ctccaattta tatctaattt
    15121 cccaagatct tttattacac tatcaagatt cttatcacct tttacaaaga atgttgcatc
    15181 ttggtataca gctgtatctt cggtattacc ataaacttta gcagctgtat gaatatcagt
    15241 gattaatgta ttttcgtata gttcttgtgc tgcacttact acaccgctat tatgcccatc
    15301 gaatagacct ttaatttcta cttctactgt ttcatctgca cctttctcat tatcagcatc
    15361 aaataaatta gattttattt ttatcttatc tccaacttta aggttatttt tttcagctaa
    15421 atctttatgc attaagattt tatttttatc ttcattttct aaatgctttc cttctactaa
    15481 tttatatgct tctgatacaa attttgtttc ttttgttgag tcgttaaccc cagttaacat
    15541 aactgttctt ttaaaattct ttgctctttc aggtgattga ttcgcaagag tctcttgagt
    15601 ttcaataata tcataatcaa ctaaatctgc aacactgttt attcttttta cataggagtc
    15661 tatactatct gtttgagata tctttttaat atcttcacct tttacatttc ccccacctct
    15721 aggtgttcct ggatttactt gtctatttat ctccatagaa aaactatttg ttatattagc
    15781 aaatgtttct tttgaagctc tgtccgtagc atctttaata gataaactaa tgagacttaa
    15841 agttgacata gataaaataa ctaatatgat aattaatgat tttaaacttt ttctagttac
    15901 ataagcaaat gcatttttta tcattattca acctccaaat tcattttatt tacttttttc
    15961 aactttttac cacttagttc taaaatgata tccgcagaat ctgctacttc cttactatgt
    16021 gttacaacta ttacacattt atttctatct ttagctaatg tctttaatat attaattatt
    16081 tctccagcag taacactgtc tagattacca gtaggctcat cagctagtat tattggagca
    16141 tctgatacca atgctctagc aatagctact ctttgttgct gtccaccaga taatttcata
    16201 acatttcttt ttatttgttt tttatctaaa cctagttcaa acaagatact ttcatctgct
    16261 gatttattta ctaatctaat attttcaatt ggtgataaat aatctattaa attatagttt
    16321 tgaaatacta aagatatatt attttttcta tgattactat atcctttatt ttgtatatct
    16381 tcattcttaa acaatatttt tcctgtttga ggtttatcaa gtccagcaag taaggaaaga
    16441 agtgtagatt ttcctgttcc tgactttcct actatcgcat aaaacttccc aagttcaaat
    16501 ttttgattta ctcctgacaa aactttttct ttagaatttg cataactata tgctacattc
    16561 tttatttcta atatatccat tattttctcc taacttattt ttgataagat ttctttaggc
    16621 ttcttgatta acattaatga agaagcaaat acaactgata aaacaataat acttattaat
    16681 attaaataac tttgtccaag tgttgttata tttgacataa aactactatt atttattaaa
    16741 cttccaccgg aaatcattga atcctctgag ttaatgaatc catctacaat tacttttagt
    16801 aatacatttc ctaaaaataa ggaagatatt atacttggta tcgatatgaa tattaactcg
    16861 aatataaatt gcattataat ttgtatctta gatgttccaa tagataagaa tatacctatt
    16921 tcataaattc tttcccttaa ccatagaatc aagattaatg aaagaacaac catcccacct
    16981 aacataatag aataagtcat tacttttatt atatatttta ttccactcac tgactctaaa
    17041 gactcttcaa acgcattaga atctttttca acaaaatact ttgactcatc aattttaagc
    17101 tctttcaatt tgtttaaggc taagtctgta gattctgcac taccagaata cattaaaatt
    17161 ttatttgcaa tttcattatt ttctgaatta tttaatatct cttggcttgt tgaataatct
    17221 acaaacacca tattttcact aaaatcagaa gataatcctg tatatgtttc ctgtttttta
    17281 ccagaaaaga tccctataat tttaaattta tgacttttta tttttccact tttttcaata
    17341 tctagtaatt caagatcaac ttcatcacct aattttagat tgttttgttt agcaaattct
    17401 tcatgaacaa taattgaatt cttatcattt tcttctatat ttttaccttc tttaattgta
    17461 aatactccac tactaaataa aatatttctt ttagtattat ttgtagcttc gagtgaaaca
    17521 acattcttaa attcgtcaga taaatcttct ctatttattc tttgttctcc gctaactact
    17581 ttagcatctt ttaattttgc taatccatca tattgaatta ttttttcttc aatttctttt
    17641 aatttttcaa tatctttaaa ttgattaaca ttaaaatatt taccatcttt ttttgttatt
    17701 gatattgaag aattagaact ttcatataaa gccttttcta tttcattgct tgatttcatt
    17761 attgttaaac aagaatacaa gcaagaaaga actatagtta atatgataaa aattattaaa
    17821 gttctatttt tctttcttgt aatatatgct atagcatttt ttatcacttt cctaactact
    17881 cctctctatt ttcttactcc ataactaatt gcatccactg gacaagcatt tttacatcgt
    17941 ccacatctga tacactccag atgattgcaa ttctcaactg aatctttatt catttggcaa
    18001 acttttttac attttccaca attaatacac ttatccttat cctgaatcgg ctacactaga
    18061 ctagacagaa aaaataaggt gtgtagaata ataaaaaaca cactggagga tttttcatgc
    18121 caagacgtca acgaagaacc tattcaaaag aattcaaaca acaaatcgtc gatctctatc
    18181 tcgctggtaa gcctcgcgca gaaattattc gagagtatga gcttacgcct tcttctttcg
    18241 ataaatggat gaagcaagca caatcaacgg gctcattcaa agaaagagac aacttaacac
    18301 cagaacaagc agaattgatc gcactaagaa agaaaaataa gcaactcgaa atggagaatg
    18361 atattttaaa gcaagcggcg ctgatattcg gacgaa
//
LOCUS       DAPBBV010000051        17891 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.051, whole genome shotgun sequence.
ACCESSION   DAPBBV010000051 DAPBBV010000000
VERSION     DAPBBV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.051"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            114..1013
                     /gene="rsgA"
                     /locus_tag="RD486_002295"
     CDS             114..1013
                     /gene="rsgA"
                     /locus_tag="RD486_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDT7664011.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            1026..1676
                     /locus_tag="RD486_002296"
     CDS             1026..1676
                     /locus_tag="RD486_002296"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDT7664012.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            1677..2315
                     /locus_tag="RD486_002297"
     CDS             1677..2315
                     /locus_tag="RD486_002297"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDT7664013.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            2470..3324
                     /gene="mreC"
                     /locus_tag="RD486_002298"
     CDS             2470..3324
                     /gene="mreC"
                     /locus_tag="RD486_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDT7664014.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVASVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            3328..3837
                     /gene="mreD"
                     /locus_tag="RD486_002299"
     CDS             3328..3837
                     /gene="mreD"
                     /locus_tag="RD486_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDT7664015.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            4092..5666
                     /locus_tag="RD486_002300"
     CDS             4092..5666
                     /locus_tag="RD486_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7664016.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(5734..7533)
                     /locus_tag="RD486_002301"
     CDS             complement(5734..7533)
                     /locus_tag="RD486_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDT7664017.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            7656..8162
                     /locus_tag="RD486_002302"
     CDS             7656..8162
                     /locus_tag="RD486_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7664018.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            8241..8963
                     /locus_tag="RD486_002303"
     CDS             8241..8963
                     /locus_tag="RD486_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7664019.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(9041..10441)
                     /locus_tag="RD486_002304"
     CDS             complement(9041..10441)
                     /locus_tag="RD486_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDT7664020.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(10611..11585)
                     /locus_tag="RD486_002305"
     CDS             complement(10611..11585)
                     /locus_tag="RD486_002305"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDT7664021.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            11938..12498
                     /locus_tag="RD486_002306"
     CDS             11938..12498
                     /locus_tag="RD486_002306"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDT7664022.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            12515..16036
                     /gene="mfd"
                     /locus_tag="RD486_002307"
     CDS             12515..16036
                     /gene="mfd"
                     /locus_tag="RD486_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDT7664023.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            16051..17649
                     /locus_tag="RD486_002308"
     CDS             16051..17649
                     /locus_tag="RD486_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7664024.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIRRL"
     gene            17731..>17891
                     /locus_tag="RD486_002309"
     CDS             17731..>17891
                     /locus_tag="RD486_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7664025.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALE"
BASE COUNT         5598 a         3352 c         3797 g         5144 t
ORIGIN      
        1 tcttttttgt gtttctatct cttttgatca attttcaagc catatacttt gagaagtttg
       61 catggaataa cacctacttt cctcttcgta tggtaaaata aacaaaaacg gaggtggcac
      121 ttatcaaagg acaaatcaga aaagcaatca gcggttttta ctatgtatac gcaaacggag
      181 agacctatca aacaagagga agaggaaatt tccggaatcg gaaaatcacg ccgcttgtcg
      241 gagatcaggt gatctttgag agtgaaaatc aaacagacgg ctatcttctg gaaatcttgc
      301 cgagaaaaaa tcaattagtt cgcccaccag tcacaaatgt tgatcttgga atcattgtca
      361 caagtatcgt agagcctgca ttttcttata atctacttga ccgctttcta gttaccttgg
      421 aatacgagtc gatcgaaccg attatttttt tgacaaagac cgacttgtca gacgacccag
      481 aaaaaatcga agagatcaag caaacctata ctaaaatagg ctatccggtg attgtaccca
      541 atcatacggg tgatacgaca gaactgatcc gttacttccc agaacggcta tcggtcttta
      601 tgggtcagtc tggagcagga aaatcgacgc tactgaatca aatatcaccg gaactgaatt
      661 tagcaacagg agagatttct gatgcacttg gaagaggacg gcatacaaca cgtcatgtgg
      721 aactgattcc tatctatggc gggttagtag cagatacacc aggatttagc tcgattgact
      781 ttttgacaat tgaagcagga gaactgccga gacaatttcc tgaatttgta gaagcttctg
      841 tccattgcaa atttagagag tgcatgcatg ctaaagaacc tggctgcgaa gtaaaacata
      901 gagtagaaac aggtggtatc gcacagacac gttacgacaa ttatttgcaa ttcttacaag
      961 aaatcgaaaa aagaaaacca atgtatgcaa aaaaagaagg taaacgaaaa taggaggaaa
     1021 caagaatgaa gatagcacca tccattttga gtgcagattt tgccaattta caaagagaca
     1081 ttgagttagt ggaaaaagga ggcgcagatt acatccacgt agatgtaatg gatggccaat
     1141 ttgtcccaaa tatcacatta gggccaaata ttgttcaggc aatccgtcct gttactaaat
     1201 taccgttaga cgtccatctg atgatcgttg atccagaaaa ctacattcca gcatttgcaa
     1261 aagctggagc agatatcatt actgtccacg tcgaagcaac tcctcatatt catcgggcac
     1321 ttcaaatgac aaaaagctta ggagttaaag ctggagtagt tatcaatcca ggaacaccag
     1381 tctccatgat caaacatgtt ttgcctttgg ctgatcaagt actagtcatg actgtcaatc
     1441 ctgggttcgg cggacaaagc tttattgaag aaacagtaga aaaaattacg gaactcgctg
     1501 atctacgtag agagaacaat tggacttatg caatcgaagt agatggcgga atcgttccag
     1561 aaacagcaaa aatctgtaaa gatgcagggg cggatgtctt cgttgcagga tcatatatct
     1621 atggagccga aaatccagtc ggacaaatcg aacgattaaa agaggcatta gactaaatga
     1681 aaattttatt agctgctgga ggtaatccgc aaaactggcc gcagtctctg ctgtccaaat
     1741 acgatgccta tgtcgggata gaccgtggtg cgctgtacct gcttcaagca ggctacccag
     1801 tagatctggc agtgggtgat tttgattcat tgtcgaacga agagcagaag gaagtatttg
     1861 caaaagccaa agagtatacc cgttcccctg cagaaaaaga cgatacagat acacagttag
     1921 gtatcttaaa aacatttgaa cgttacccgc aagcggaagt cactttgatt ggagctacgg
     1981 gcggaagatt ggatcatctt ttagccaatc tctggttagg tatggaacct cgcttcaaac
     2041 cctttgccca tcagcttatt atcagagatt gtcaaaatta tttgtcttat tatttgcctg
     2101 gagagcatat agtaagacag ataccagata tgaagtattt agcttattgc tgcttgactc
     2161 ccgtctcgaa tcttacatta aaaggcagca agtatgtatt ggaaaataaa gaagtagaat
     2221 atccgacatc ttatgcaagt aacgaatttc tttcagatac cgcagaattt tctttttcag
     2281 atggtatgat tgcagttatt caaagcaaag attgatccat aaacaaataa aaaaatttgt
     2341 ctttcaggct aaaaatgaca gaatctatta tttgctaaaa aaaagcttaa gaggagcaac
     2401 ttaccttttg tttcacggca tttagtgata aaattgaaca caagagtcta attaattcga
     2461 ggtgtctttg tgaagaagtt caatcctaat aaaaatatta ttattacctt ggttattgtt
     2521 atcatcgtgg tgacgatact aagtgtgacc gctgcgcagc gagcgaatga aggaaagccc
     2581 aatttcttcc aatccatcgt taatgacagt gttgcaatgg ttgataaaac aatctctgcc
     2641 ccagtacggt gggtacgaaa tggagtagct tctgtccata atcttttttc aacttatgcc
     2701 gaaaatgagc ggctaaaaga aaaaatcgat agctatgatg acgtttcaca gcaaaacaag
     2761 aattacgaga gagaaatcga agcgttgaaa aaagaacttg agttgaatca gacgctgact
     2821 agttacgaaa aagtaacggc aaatgtcatt actcgttcgc ctgacagttg gcaggacatg
     2881 ctgatcgtag acaagggttc taaagacggt atcgaagcaa atatggcagt catgtcgcaa
     2941 aaaggattga ttggccgagt gatcgaggtc aatacggctt cgtctaaaat cgaattactg
     3001 tcatcctcta atgaaagctc caatcatttt ccagtacggg tatcttcggc taatggcgaa
     3061 gcgtttggtt tgcttaaaaa ctatgatgaa aagctccatg ccttagtggt gacccaatta
     3121 actggtgata cggatatcaa agaaggggat gttgtccaga catccggtct tggagggaat
     3181 tctccagcta acttgccgat cggtacggtt attaaaacga aaccagatag ttatgggctg
     3241 gatcgggaag tttatgtgaa accttatgca gaaatgtatg acgtgtcagt tgtgacgatt
     3301 gtccaacggc tagcggagga ttagtccatg ttgaagaaag aaacaatgaa gtactatctg
     3361 ccaatcgttt tgttcttttt gatgttgata gatggtcatt taacaagaat gctaggggag
     3421 tggtcgaaag gcacctatat gtcaaatgcc cactttctga tattggcatt attatgttgc
     3481 agtatggcgt ttgaaaaacg ttatttactg attaccacga ttgttctcgg ggctatctat
     3541 gacgcttact atattggcgt tatcggtatc tatgcagtag ctctcccttt aattgtatgg
     3601 ttgatgtatg taatgaaaga cgttatccat gtcaacatct ttactgaatt tttcagtatg
     3661 atcatctttg tcacgggtta tgaattgttt acgatggtgg tccagttgat ttttaaatta
     3721 gcagtagtaa ataacacgta ttttattaca aggtttttag gacctacact gctgttgaac
     3781 atgattatat ttgtattatt catttttccc tttaagaaat tattcagtga tgaataattt
     3841 ctttttttat ttttaggtcg aaagcgaaaa agaatcgttg ttatcttaag aaatgctaga
     3901 cttaacgcgg ctttttcatg atcattttct gaaacgaaca gttttgtcat ttttaaaagt
     3961 tgttttgaaa catttttgta acataactat tatatcgttg acacactgct atggtacaat
     4021 ttttatatcg ttaagaaaga cttaaatata tttagatatt tattaaatta agccagtcgg
     4081 aggaatgaag agtgaaaaag agtttaatat cagcagtaat ggtatgttca atgaccttga
     4141 ctgccgtagc atcaccgatc gctgccgcgg cggacgattt tgattctcag atacaacagc
     4201 aagatcaaaa gattgcagac ttgaaaaatc aacaagcaga tgcacaatca caaatcgatg
     4261 ccttagaaag ccaagtttct gaaatcaaca cacaagcaca agacctatta gcaaaacaag
     4321 atacattgcg tcaagaatct gcacaattag taaaagacat tgcagattta caagaacgta
     4381 ttgaaaaacg tgaagataca atccaaaaac aagcacgcga agcacaagta agcaacacaa
     4441 gctcaaacta catcgatgct gtattgaatg ctgattcatt agcagatgct attggacgcg
     4501 ttcaagcaat gacaacgatg gtaaaagcaa acaacgactt gatggaacaa caaaaacaag
     4561 ataaaaaagc tgtagaagac aaaaaagctg aaaacgatgc taaactaaaa gaattagctg
     4621 aaaaccaagc tgctttggaa tctcaaaaag gcgatctttt atctaaacaa gctgatttga
     4681 acgtactgaa aacttcatta gctgctgaac aagcaactgc tgaagacaag aaagctgact
     4741 tgaaccgtca aaaagcagaa gctgaagcag agcaagctcg tattcgtgaa caacaacgtc
     4801 tagcagaaca agctcgtcaa caagctgcac aagaaaaagc tgaaaaagaa gcacgcgaac
     4861 aagcagaggc tgaagcacaa gctactcaag cttcatctac tgcacaaagc tcagcaacag
     4921 aagaatcatc agctacacaa tcttcaatga ctgaagaatc atcatcagct acacaatctt
     4981 cagcaacaga agaatcaaca acacctgaat cttcaacaga agaatcaaca gcgcctgaat
     5041 cttcagcaac agaagaatca acaacagcgc ctgaatcttc agcaacagaa gaatcaacaa
     5101 cagtgcctga atcttcagca acagaagaat caacaacagt gcctgaatct tcaacaacag
     5161 aagaatcaac aacacctgcg cctacaacac catcaacaga tcaaagtgtt gatacaggaa
     5221 acggcacagg aagtagtact ccggctccaa cgccaacacc aacacctgaa caaccaaaac
     5281 ctgtaacacc tgctccagct ccttctggaa gtgtgaatgg tgcagcaatc gtagcagaag
     5341 cttacaaata tattggtact ccatatgttt ggggcggtaa agatccaagt ggctttgact
     5401 gctcagggtt cacacgctat gtttacatgc aagtaactgg tcgtgacatc ggtggttgga
     5461 cagttcctca agaatcagct ggaacaaaaa tttcagtttc tcaagcaaaa gctggagact
     5521 tgttattctg ggggtcacaa ggcggaactt accacgtagc gattgcttta ggcggaggac
     5581 aatatatcca tgctcctcaa ccaggcgaaa gcgtaaaagt tggttcagtt caatggtttg
     5641 cccctgactt tgctgtcagc atgtaagaat gattaatcaa aaagagttag cccattctgg
     5701 actaactctt tttttattgt gataaaatag aaatcagata aattcttctg tcaattccat
     5761 gaacgtttgg atatcttcag tcaccatgtc gatacctgct tgccaaaaat ctggttgggt
     5821 aagatcgaca ttcaaatgtt tcttcgcaag atcttccgtc gtcattgagg cagtatcgcg
     5881 tagtaaatgg atatattctt cttcaaaatt tgctcccttt tggttggcgt aagcatagat
     5941 gcccaaacta aagaggtagc caaatgtgta tgggaagtta taaaacggta cgtcatcaat
     6001 aaagaaatgc aattttgcag cccagaaata tggatggtaa gtagctaaag ctccttgata
     6061 gccttctttt tgcgcctcaa ccatcatctc tgtgatctta tcttctgaga ctaatccttc
     6121 ttgccgtgct tcatagaatc gattttcaaa aatgaatcgg gaatggatat tcatgaacat
     6181 agctaaagca ttttgcagtt ttgtatctag caaattgatt ttttcttctt ttgtttttgc
     6241 gacttttaat gtagcatcgg ctacgatcag ttctgcgaat gtacttgctg tttctgcgac
     6301 attcatggca tattcgcgat ttaaagaagg taaatcccac atcgtgctgc tatggaaagc
     6361 atgtcctagt tcatgagcaa gtgtcgcaac ctcattaaca gaattactgt aggtcataaa
     6421 gatccttgat tcttttgttt ctggtaactc agtacaataa ccaccaggac gtttcccagg
     6481 acgatcttct gcttcgatcc agctcttttc aaaagcagat tgggcaaatt tagccatttt
     6541 tggactgaat ttgttaaagt tttcgataat aaatgctgct gcttcgtcaa aactaaaggt
     6601 tttttctttc aaatcgccta aaataatagg tgcatcttga tcttgccatt ccattttttc
     6661 tttaccgaaa agattagctt ttctagtcaa gtaattaaca aggggttgtt tgtttttctg
     6721 gattgtatcc cacatgacag acaatgtttc tttcttcaac cgattgtact ctaatggttt
     6781 ttgtagaaaa tctgtgacac catgaagttc atagtcagaa agtctaaaac catctaaatg
     6841 attcaaagta tccgtgaaga ggggtgcctt ttctttccag gcttcttccc atgctgcgaa
     6901 aagtgtttct ctgacttttg gatctggatc gcccatcatc ttattgaagg cttgtccagc
     6961 agataattcg actacttgtc catcttgttc gaagggaatc gaaatgctgg ctacaatcgt
     7021 atcataatga ctgctccaag catttagacc atctaaagaa agcgtattta taatgttttc
     7081 ttcagcttct gataataatt gtgagccatc acgacgaatc tcgtttaaac gaaaagcaat
     7141 tgtttcaaac gaagattgag aaagcatctg attccaatca ttgtcagata tttctgcaaa
     7201 tttctttgac aatacagttt cggctgattg cagacgaggc agcattgcgt aaagcttgcc
     7261 tgataagacc tttgcatctg aatcattgac attggcagaa agcaatgcag taatatagct
     7321 gctgcattgg gtaaaaccat tcgtaatcgt ttcttgcaat tgaagaatag cgtttaactg
     7381 ctctgcattg tcagaactag gtgaccattt tgttacgcgg tgataatact cgttcatttg
     7441 gtcttccaat tgcttcatcc gttggttcaa agcatcagaa tgactgcctc cggaaaaaat
     7501 agaatctaga ttccaattta atgaataact catgaaaaaa ctcccttcat attgtaatac
     7561 aaaattaagt atagcacttt tttatggaag aagtctctat gaaaatgatt gttgtttctt
     7621 caaaaaaagt ctaagataaa atacagaggt gacttatgaa ttcttcaaaa aaacaaatga
     7681 aaaacggaaa tatttattta gtaatcgcac tgatagtcgt tataatctta ttttacagtt
     7741 cttctcaaac ttacggacag caatcacaag tttcgcgatt agaaagctgg ctgcctaatc
     7801 agccatttaa agacacatta gcgggtatac gttttaatta tggtggaagt atggtgagta
     7861 tcgaccatct gggctacgcc aaatttttag agttcttttt aaggaagggc gcacatttcg
     7921 gtacctattt tattttggga ggcagcttgt ttttaggtgt tttccccaag ctaaaaattt
     7981 ggtggctgac agcgatcctt gcttggcttt cagcaacagg gtacgcaggt ttggacgaat
     8041 tccatcagat gatgaccggt ggacgaacac ctatgttcca agatgtcatg ttggattcga
     8101 tcggtgctct gactgctgtg atattatgtg tgctttttgc ggcattcaag aagcgtttat
     8161 agattggctg tggctttgtt tttttgtgaa atagtactag aatagaagtg tattctcaaa
     8221 agaacaaggg aggaaaaatc atgtcaggac atagtaaatg gcataatatc caaggaagaa
     8281 aaaatgccca agatgcaaaa cgagggaaag tctttcagaa actttctcgt gaaatttata
     8341 tggcagctaa agcaggcggt cctgatccat ctatgaatcc agctttgcgg cttgttgtgg
     8401 acaaagcaaa agctgcaaat atgcctaacg acaatgtgga acgggcgatt aaaaaggcta
     8461 cgagtgccgt agatgaaacg aattacgatg aaatcacgta tgaaggatat ggtccgggtg
     8521 gagtaggaat cttagtccat gcattgacag ataaccgtaa tcggacagcg acaaatgtcc
     8581 gagtagcttt tactcgaaac ggtggatcac tgggagaaac gggttcagtc agttacttgt
     8641 ttgaccgcaa aggatatatc gctattgaac gcgatgggtt gactgttgat gaagagacga
     8701 tgtttgagga tgtattagag gcgggggcag aagatctgca aacttctcct gaagtattcg
     8761 agatttatac tgcaccagaa gattttgctg ctgtacgaga tgagttggaa aaagagttca
     8821 ctttggcgca agcagaattg acgatgattc cacaaacgac gattgattta aatgaggaac
     8881 aaaaagagca attggaacgt ctagtagata agctagaaga cgatgatgat gtttcagaag
     8941 tctttactgc tgctgaaatg taagtagcac attgttagat aataaaaaga aagcacctgt
     9001 accaatcgta cgggtgcttt ctttttatat attatttttg ttagaagacc aatacaggcg
     9061 ttcctttttc gaccatcccg aataattcct tcattacact tggtggggtg ttgatgcagc
     9121 cgtgtgaacc gcgggttttc cataagtctc caccgtattc aggttgccag tctgaatcgt
     9181 ggataccaac acctgtccag tcaatcggca tccagtagtt taccggactc tcgtaaggtg
     9241 ttccatcgtc atttgttcct tttaaagttg catcttcttc tttattccaa acatagaaga
     9301 ctccagcagg tgtaggtgta gttggctttc cggaaacgat atctgtttca agggccactt
     9361 ttccgtcttt gtaataccac atatgctggt tctccagatc aacttcgata tacgtatctt
     9421 cgatcaatgg atgatcagcg gttgtgccac cttgcacaat gggtgaacga gtaaaatctt
     9481 ggcctgccag aatcgctttt ttcaatgctt ctgtctcact gtctgtttgg atcgtccaac
     9541 tgtaagtgcc aactgggacc gtaacttctc ctctttttgt acttttaaat tttgtgtcat
     9601 tcgtacttgt gttatacttt gtgcctaaat ctgttacata ttgacgtact tgttctgtat
     9661 ctaaatcgac ttttccatca ttgtaggtca gccaactcat aatatcactt gatgggatct
     9721 ggaaagtctc accgtttata ctgtaagtag cttttacatt tgcgatagca ttcatggatg
     9781 cgagttgttc tttcagtgag ctgtcttcag atgttacttt tggtttttct ttgaattcag
     9841 tcaattcaat tgtatcttta ccagagttta ccgcactttt taattgtttg accgcagcat
     9901 cgacgtcgat cgtatttcca ttgacttcag gcttgataac gaaagagtca cctgcttttt
     9961 cgatcgttgc atcagtagta ggtgtccggt ctttgttcaa atcagtcagc ttagttgtca
    10021 atgtctgaac ggtagtgtct agtttttggt ggttttgact gacaggatct atttcttgtt
    10081 tttctgccgc tgagacataa gtcattcccc aagtccatcc gttttgttca tttaggatcg
    10141 gagaaagctc cgaagtgaaa tcatctttgt agccgagctc ggattttggt acttcctgcc
    10201 agacttttcc atcttcttta atagccagtt ttttatcaga ataagcttct tttaattttt
    10261 catttgcttt ttcgactgtt agattgctga catttattcc atttatttct gtattcggca
    10321 aaaaatgctt tgtgtagtat gtactgcgat aggtataaaa gctgatcagc actaagagaa
    10381 caccaagaac tgaaagcaaa gcaacatgtt tcgatttttt tcgatgcgaa gatcttgtca
    10441 tatcgacaac tccttaagta aaagtttagg gtggaacggt ctcatgatag cataatttag
    10501 aggaaaagac gaaggttatc tctactttat gaaaaaattt agaaaccata agggtgataa
    10561 aataaaaaaa cggaaaacac cgaatagatg ttttccgtca tgttcaaaga ttattcagcg
    10621 tctagtttag caaaagcttc atctagaatt tcttttaatt gcttagcaga agcagccata
    10681 cggtcttgct cgctgtcact taaaggaatt tcgattactt tttggatacc ttgacggttg
    10741 ataacagcag gtgcaccaat gtagatgtcg ttcaatccat attcgccatt catgaatact
    10801 gataaaggaa gaacagcatt ttcatcatct aagatggcac gagtgatacg tgctaatgct
    10861 actgcgatac catagaaagt agcgcctttt ttctcgataa ttgtgtaagc agcgtcacgt
    10921 acgccaaaga ataggttaac catagcttct tcatcgattt ctgggttgtt ttttacccat
    10981 tcatagattt gcaagccggc aacatttgca tgtgaccaaa ctgggaattc tgaatctccg
    11041 tgttcaccta agatgtaagc atggacgtta cgtgcatcaa cgtcaactaa ttccgcaagt
    11101 gcttgacgga aacgagctga gtcaagagag gtacctgaac cgattacgcg ttctttaggg
    11161 aaacctgaga atttccaagt tgagtaagtc aaaatatcta ctgggttagc ggcaactaaa
    11221 aagataccgt taaatcctga ttcaacgatt tgtgtgacaa catcgcggtt gatttttagg
    11281 tttttgttta ctaagtctaa acgagtttca cctggttttt gtggtgcgcc agctgtaata
    11341 acaactaagt cagcatcatg tgcgtctgcg taagtagcag aatagatttt tttaggtgaa
    11401 gtaaatgcca aagcgtgaga caagtcaatt gcgtctcctt cagttttagc agtattgata
    11461 tccacaatac ctacttcttg agcgatattt tgagtaacta gagcaaaggc atagctagaa
    11521 cctacggcgc cgtctccaac aagaataact ttttgatgat cttttttttc tgcagctgca
    11581 gtcatttagt atcaatcctt ccattgattt gttttttccc atgcttatgc taacatttct
    11641 caagccccat gtcacgctat ttggctataa aatataacag ataacaaggt tgtattatat
    11701 gtaaaagctt acatgtgcgt tatttcacta tttttatata tcaattattt cattaaactt
    11761 tgaagaaatt tttaatttat ttatcattta ttaacgattc tcttttagcc gaaacgcctt
    11821 gttttgtgtt atactatgca ttgacaagta taaaaaagaa aaaagctcga tggactggac
    11881 cgctaattag cagtccagcc ttttgtgctg ctttttagaa ttaggtggaa aacaaaaatg
    11941 aaaatgatcg tcgggttagg aaacccaggt accaaatacc aatatacaaa acacaatatc
    12001 ggctttatgg tcgtggataa aattgcacgc gagcatcaag ctactttcaa aaaaaatccg
    12061 ttcgaagcag aagttgccga attttttcat aatggagaaa agatcctttt agtcaaacca
    12121 caaacattca tgaatgaatc tggtcgtgca gtcggcccac taatgactta ttttgggatt
    12181 tatccagagg aattagtcgt aatctacgat gatttggatc tggcagtggg aaaaatccgg
    12241 ctccgtcaaa agggaagtgc cggcgggcat aacggtatca aaagtattat ttcccatttg
    12301 aatacgaatg tctttgatcg aatcaaggtg ggaatcggca ggccagaagg gaaaaaaaca
    12361 gtagtccagc atgtgcttag tcctttcagc aaagaaaatc agcctttgat agaagaaagc
    12421 atgtgtcaat ctgttaaagc agtcgaatat ctcatagaag ggcattcgtt cgtggatgcg
    12481 atgaatcgat tcaattgagg aaggaggaaa aggaatggat attattcaat tagtcggaaa
    12541 agatccgcaa gtaaaagaat gggtcagcaa tttagaagaa aaaatgccta gacaactaat
    12601 cacaggatta gcgggctcag cgaaaacact tctatttgct cgagcgttta agaaaacaaa
    12661 taaaaacatg attattctga tgccaaattt gtattatgcg aatcagttag cagaagatct
    12721 gcaacatgtg attccgcaag atcagatcca tttatttcca gtggatgaag tgctttctgc
    12781 tgaaatggcc ttttcttctc cagaagcgcg aggcgagaga gttgcaacgc ttaacgcact
    12841 tcaagaaaaa aaagcaggta tctatttgtt gccagtcgca tctttgcaca aacgactgcc
    12901 gaataagaaa acttggctac aggcgcaatt gaattggcat attggtgatg agatagacgt
    12961 ggaaaatctt cctcgccaat tgactttgat gggctatgta cgagaagaga tggtcgcaaa
    13021 accgggagaa ttcagtattc gaggaagcat tatcgatatt tacccgttaa cgacaaccta
    13081 tcctgttcgt gtagaactat ttgatgtaga gatagattct atgcggtatt ttgaagcaga
    13141 aacacaacgc tcaatcgaaa aaacggaaga aatctgggtt tccccaacga gtgaacaagt
    13201 ctacggacca gaggatctag aacatggaat agagcaaatg caaaaaatgc tagaaaaacg
    13261 gcttgctgcg accacagaag aagcagaccg cgagtttttg caagattact tcggtcagct
    13321 gacttcaagc tggcaagcag gtgtcccgac agaagaagca aaattctact cagatcttct
    13381 ttaccaagaa tctgtgacga tcttggatta tttcccttca aatagtttac tagtcgttga
    13441 tgattatcag cgaatcatgg aaacaaatcg ggaaatcgaa agggaagcgg cagaatggca
    13501 gactcaaaaa atcagcgaat tgcgggtgtt ttctgagcag acattttcag cagatataca
    13561 aaaaatcgtg cagaaggaaa agttcaccac aacctttttc tcactcttcc aaaaagggat
    13621 gggaaatctt cgtttccaag caatccataa ttttcaatat cggacgatgc aacagttctt
    13681 cggacaaatg ccattgctga aaacagaaat ggaccgttgg cgcaagcaaa aacagactgt
    13741 tgtgatcttt attccgacaa aggacagaat acgcaaagca gaacaaatgc ttcgagatga
    13801 agacatatta gtagtagaaa cagaaaaaaa tgcattgatc agaggacagg tacaattagt
    13861 tgaaggagct ttgcaggctg gttttgaact tcctcaagaa aaaatagtag ctatcacaga
    13921 aaaagaaatt ttccaaaaaa cgacgaaaaa acaaacgaga cgtcaaacag taacaaacgc
    13981 agagcgattg aaaagctata atgagttaaa agcaggagat tacgttgtcc atgccaatca
    14041 tggtatcggg aaatacattg ggatggaaac gctagaagta gatggcgttc accaagacta
    14101 tatgactatt ttgtatcaaa acgacgacaa actgtttatt cctgttactc aactgaatct
    14161 gatccaaaaa tatgtcgcct ctgaagccaa agcgcctcgc atcaataagc taggcggaag
    14221 tgaatggacg aaaaccaagc gaaaagtctc ttcaaaaatc gaggatatcg ctgacgatct
    14281 aatcaaatta tatgccgcaa gagagtcaga aaaaggatat gcttttggac ctgatgacgc
    14341 ctaccaaaaa gaattcgaaa atgccttccc ctactctgaa actgatgacc agttgagaag
    14401 tgcagcggag atcaaacggg atatggaaaa agaaaaacca atggatcgac tactcgtagg
    14461 tgatgttggt tatgggaaaa cagaagtagc gcttcgagcg gcctttaaag cgataaagga
    14521 aagcaaacaa gtagcctttt tagttccaac aacgatcttg gcacagcagc actatgaaac
    14581 gatgctggaa agatttgaag gtttccccgt aaatatcggg ctattaagtc gtttcagaac
    14641 aagaaagcaa caaaaagaaa ccatcgaaca actgcgtaca ggtcaagttg atattgttgt
    14701 aggaacccac cgaattttgt caaaagatat tgaatttagc gatttgggtc tactgatcat
    14761 tgacgaagaa caacgttttg gtgtaaaaca taaggaacga ttgaaacagt tacgtgcaca
    14821 agtggatgtt ttgactctga ctgcaacacc gattccgaga actttgcata tgtcgatgtt
    14881 aggcgtgcgg gatctttcag taatcgaaac accgcctgcg aatcgttatc cgatccaaac
    14941 gtatgttatg gaaaaaaatc ctggggctat tcgcgaagca atccatcgag aaatgggacg
    15001 aggtggacaa gtattctatt tatataatcg ggtagaaacg atcgaacaaa aagtagaaga
    15061 aatccaagaa ctcgttccgg aagcacggat cggttatgct catgggcaaa tgacagaggc
    15121 gcaattagaa aatacgcttt ttgaatttat tgaaggtcaa tatgatgttc ttgtcactac
    15181 aaccatcatt gaaacaggag tagatatccc gaacgcaaat acgttgttcg ttgagaacgc
    15241 tgattatatg ggattatcca cgttatacca attgcgaggg cgggtaggaa gaagcagccg
    15301 tgtcgcatat gcttacttta tgtatgagca gcagaagatc cttaacgaag tcagtgaaaa
    15361 acgtcttcag gcaatcaaag attttacaga actgggatct ggattcaaga ttgcgatgcg
    15421 ggatctttcc attcgcggtg caggtaatct cttaggtgct cagcagcatg gatttattga
    15481 tgcagtcggt ttcgatatgt attctcaaat gctaagcgaa gctgtttctc gtaaacaagg
    15541 aaagaatagt caagtggaga agaccactgt tgagatcgac ctcggtgtcg atgcgtatct
    15601 acctgaaaca tacgtggcag atcaacggca gaaaatcgag atctataaac gaattcgtga
    15661 acttgattcg caagaaatgc tagatgaact agaagatgat ctgctcgacc gttttggaga
    15721 atatccagaa gaagtagcac atctcttgac aattgggcag atcaaaatgg atggcgatcg
    15781 agcgctccta gaaacgataa ggaaacagga ggcgcatata gtctttactc taagtaaagt
    15841 tggaacaaaa cgctatagtg tggaacagtt attcgaagca ctgacagcga caaaactaaa
    15901 agccagtcta ggcgttgaaa aagaacagat ggtgatacgc ttgacgatcc ccaaccaaat
    15961 ggaagaagca gtatggcttc aggaaatcca aaagtttgtc aaagcgttgc gtgagcaaaa
    16021 atatctgtca gcgtaggaag gagcaatgat ttggatcata aagaaatgcg gcgcgtcatg
    16081 caaggagcat ttgtattgac gattgcttct ttcatagcaa aagtattaag tgccctttac
    16141 cgaattcccc tccaaaactt agtcggcgac gaaggttttt atgtttatca gcaagtttat
    16201 ccaatttatg ggatagcaat gactttagct ttatccggtc ttccgcagtt catatcaaag
    16261 tacgttgcag aaagaaagaa tcctttcgag cgaaagcaag ctttgcaaaa tctttatccc
    16321 ttagtatttt ggacaggtgt ctttttgtgg ttgtttgtct ttgcatttag cagctggatt
    16381 gcttggatga tgggagacat acaattgaaa ccgctgatcc aagtagtttc ctttaccttt
    16441 ttgctgatgc ctggtctatc tttttatcga gggaatttcc aaggaagatt cttgatggaa
    16501 ccaactgctg tttctcaagt agttgagcag ttcgttcgtg tttttgtgat tgtctgtagt
    16561 gcgtttgctt ttagaaagct tggatggacg gtgtaccaaa cagggacggc agcaatgagt
    16621 ggagctgttt ttggcggttt atgcgcatat gggatccttc actactatga acaaaagatt
    16681 catggaggag cgttaagctt ccgacggttt ccattgttca aacagccgtc aaagcccttg
    16741 atccggcgtt ttctggtaga aggcggactg gtttcgattt atagtggatt gcttatcttt
    16801 ttccagctga tcgactcttt ctttgtaaaa aatgctttgg aagtttacgg actgtcagaa
    16861 tacggtgcga agatagcaaa aggggtctat gatcgaggtc agcctttagt acaattaggt
    16921 ttagtgattg ccactgcatt aagtgcgaca ttcctgcctg cgttgactcg tcatttgacc
    16981 aaccggatct atcgtcagtt tttacagaca gccaaaatct atcttagatt gacgaccgct
    17041 ttagcattag ctgcgtcttt gggattagcc ttgctgctcc cttatatcaa ttatgcgttg
    17101 tttaaagatt atgcgggaaa tgcagcgctt gtattatttg ttttttccat tgctttcact
    17161 gcagtcatcc aagcttatca aagtattgct caaagcaaga actcgtttcg cccttcttta
    17221 aaaggcgcag gatggggact attggtaaaa ggattgacta cttcttttct gaccggttta
    17281 ttaggaacag caggtgcaag cctgtctacc cttttaggat taggtgtgac gctttggtat
    17341 tttgttcgaa ttgaaacaaa agagctaaat gctttttgga aagaacggca ttttggacgg
    17401 aagttgatgt tcagccttct ttgtatgaca gtagtactgc tgctgtatta tggtgtattg
    17461 aatatagtat ttggtcctgt aactcatcgt tccactgctt tttttgtcag cgtgatagga
    17521 gttgggatcg gggcttctgt gttcatttat gcagtgattc gtcttcgtct gtttacagta
    17581 cgagaatggc taatgttgcc ttttggtaag aaaatcctgc gattaaataa aaaaattcgc
    17641 cgattgtaaa attaagctag acaactaaaa aagtcatttg tgctacactc aaaatagttc
    17701 cgaccaaaga attataagga gtgagtacaa atgacctata cccatcttac aacggatgaa
    17761 cttgtaataa tagagtctta tttcaaaatg aatcaatctg ttgctaaaac tgcccattgc
    17821 ttgaatcgtt caagacaaac gatccataaa gtatacctgt tcttcaagca aggaaaatca
    17881 gccttagagt a
//
LOCUS       DAPBBV010000052        17007 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.052, whole genome shotgun sequence.
ACCESSION   DAPBBV010000052 DAPBBV010000000
VERSION     DAPBBV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.052"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..126)
                     /locus_tag="RD486_002310"
     CDS             complement(<1..126)
                     /locus_tag="RD486_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HDT7664026.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(230..541)
                     /locus_tag="RD486_002311"
     CDS             complement(230..541)
                     /locus_tag="RD486_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7664027.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(543..740)
                     /locus_tag="RD486_002312"
     CDS             complement(543..740)
                     /locus_tag="RD486_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HDT7664028.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1134..2861)
                     /locus_tag="RD486_002313"
     CDS             complement(1134..2861)
                     /locus_tag="RD486_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HDT7664029.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2854..4047)
                     /locus_tag="RD486_002314"
     CDS             complement(2854..4047)
                     /locus_tag="RD486_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7664030.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4234..4878)
                     /locus_tag="RD486_002315"
     CDS             complement(4234..4878)
                     /locus_tag="RD486_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7664031.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4972..5106)
                     /locus_tag="RD486_002316"
     CDS             complement(4972..5106)
                     /locus_tag="RD486_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDT7664032.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="RD486_002317"
     CDS             complement(5108..7240)
                     /gene="feoB"
                     /locus_tag="RD486_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDT7664033.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7237..7710)
                     /locus_tag="RD486_002318"
     CDS             complement(7237..7710)
                     /locus_tag="RD486_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDT7664034.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8111..8335
                     /gene="nrdH"
                     /locus_tag="RD486_002319"
     CDS             8111..8335
                     /gene="nrdH"
                     /locus_tag="RD486_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDT7664035.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8494..10653
                     /gene="nrdE"
                     /locus_tag="RD486_002320"
     CDS             8494..10653
                     /gene="nrdE"
                     /locus_tag="RD486_002320"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDT7664036.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10703..11668
                     /gene="nrdF"
                     /locus_tag="RD486_002321"
     CDS             10703..11668
                     /gene="nrdF"
                     /locus_tag="RD486_002321"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDT7664037.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11757..12896)
                     /locus_tag="RD486_002322"
     CDS             complement(11757..12896)
                     /locus_tag="RD486_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7664038.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13205..13918)
                     /locus_tag="RD486_002323"
     CDS             complement(13205..13918)
                     /locus_tag="RD486_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDT7664039.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="RD486_002324"
     CDS             complement(14172..14873)
                     /gene="nagB"
                     /locus_tag="RD486_002324"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDT7664040.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15107..16639
                     /locus_tag="RD486_002325"
     CDS             15107..16639
                     /locus_tag="RD486_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7664041.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16830..>17007)
                     /locus_tag="RD486_002326"
     CDS             complement(16830..>17007)
                     /locus_tag="RD486_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7664042.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5324 t
ORIGIN      
        1 tgaaaaaaca cattccacta aatttgatgc cggttttcct tgaggttttg ttccagcacc
       61 tcctttaatt tttttaagct cttgatctga acattgttta gcatttagtc tatttttttc
      121 ttccattacg attcccccta caaactataa atacttttat gtcactgatt caatatacct
      181 atttttctaa tcaaaaaatt ttgagacata tttaatatta taagtatcat taaaattgag
      241 atttatctcc ataatctgct cgatataaac catttattcc agcagttctt ccaatttcac
      301 tcaaatttct tattaattcc tcttgatatt cagtgaatct tattttatta gtataagcag
      361 taaaatatag ataattcacc aatctattta ttaaaggact gggatctaat tcatattttt
      421 gtttttctaa ttttaaatat accttttgta aaacctcaag aatatcagaa tatttaggat
      481 ctttacttat agatatatca ttatataatt catgaacaat ttgcttagca ttttttttca
      541 ttttagcact tccctggaat tgctccacct aaaaaaccac ctatagacat tcctgcaata
      601 caagtagttg ccttggccca atcgaccgta catttatttt tagtgcaata cactccattt
      661 ccataatatt ttccactatg agtggtaccc ccatagataa gttgtgtctc tttaatagac
      721 aaaattttta aatgtttcat aatctaatca cccctaaatt aatgttttta gactattatt
      781 ctaacattca ttaaatttca aaaaacaatt ccttcttgaa acgtagcaaa ataattcctg
      841 aataagaatt taatcacttt taagtatata aactatgtat attctttaat attttttgag
      901 aatgcacttc gtacataata aactttaatc acattagtct ttcataccta cgatcgatct
      961 ctttgactcg cacccataaa ttcataatag tttgtcggcg tctttgaacg tttcgaagat
     1021 gagctacgca ttctcttttt ttatagacaa aaaagataga gacgaacatg gagcttccaa
     1081 atttggatat ttgatccaat tttggaagct ccatttattt cgtgtctgtc tttttatttt
     1141 ttccagcttt cgactaattc ttggttctct ttgatccagt cttttgctgc ttgctgtgga
     1201 tcttttccat tgttgatttc caacataact ttttccatat ctttttctga ccaatggaaa
     1261 ttgtctaata ctttgtaagc ttctggctgg tcttctttca atccttttcg aaccatcgta
     1321 tggatctgct cttcgcttcc cattccgttt tcaggatctt ctaagtattt cagatcatat
     1381 ttggcaaaca tccaatgagg tgtccatcct gtaactacaa ttggttcgtg ttttttgatc
     1441 gcttgaccta gtgcaacggt cattgctcct gaagaagatg tctctacttt ccagtctttc
     1501 aagttgtcat atttttggat cgtgttttca gcagccgtaa ctacaccagc tcctggctcg
     1561 attcctatga ttttcttacc tgcctgatcg gttaactcat cgatcgaatt tacatccatg
     1621 taggctggca ctgctaaacc aacttttgct cctgtcaaat tggcacctag gtcttcgact
     1681 tgatctttat attgtgcata ttgtgaacca tgagttttag gtagccaagc tgaaaccatg
     1741 gcatctgact cgccatttga aacagatttc cacatgattg aattatctaa tggcgtcatc
     1801 gttacatcat agcccatttg tttcaatact tcaccgacta catttgttga agcaacttct
     1861 gtatcccatt caacataaga taagttgata cgttttgttt ctttggcaga tgaaaaactc
     1921 cctataccaa tcgcacctaa gatcactact actacagcac caatgatcag tccttgacgt
     1981 tttttacttt tctgtgttgt tgctcctgca gcttttttat tgtttggctg gttcaaatgc
     2041 tgtgtaaaac ggtcaatgat gattgctaag ataactaatg caaccccgtt gacaaatcca
     2101 ttcccgactt gtgctctttg caatgctgat aatacgccgc gtcctaagcc gggtgcaccg
     2161 atcatagagg caataacgac cattgaaagt gacagcattg ttgtttgatt gatccctgcc
     2221 atgatcgtac ttttagctaa aggcaattct agtttgaata gtttttgacg acttgtgctc
     2281 ccgaatgaat cagaagcttc tactaattct ttaggaactt gtcgaatccc taaattcgta
     2341 aaacgaacgg ttggtggcag agcaaagatg actgaggcaa atacccctgg aaccatcccg
     2401 ataccgaaaa atgcaactgc tggaatcaaa taaacgaatc ctggcattgt ctgcataaag
     2461 tcaaggatcg gtttgataat actttgggct ttactgcttt ttgccatcaa gatccctaat
     2521 ggtaccccaa tgatgatcga gatcacacta gataaaagaa caagtgtgac agtattcatc
     2581 aaatcattcc atagaccttg gttataaata aaccatagac cgattaatgt gaacaacgta
     2641 agtcctggac gtttcttaga aataaagaaa gctgctaccg tcaataacaa gataaacaaa
     2701 ggagctggaa tcactaacag taaatttgta atccccgaca tcactgcctg tccaatcgtt
     2761 tgtaaaaatg aaaataggcc agaaaaagtt gtcgtaaacc attctgtgat attttctacc
     2821 cagtttgcca ctggtaattg atagttcaat agattattca tgttcactca cctcgcttgt
     2881 ttctgctaat gcttcaatca cactacctcg gatgacgaca ccttttaatt ttccatcctc
     2941 tacaactgca agtggagtcg gtgagtcata aataatattg aaaatatcac ttaccaccat
     3001 gtctttccca atcaccgtca cattttcatc taggaagtcg atcaatggac gtttttgctt
     3061 cctagcttct aacgcttgat ctgcagtgat gatccctttc aggtgtctct ttctgtcaac
     3121 agccatcagc atgctgactt cttcattacg catccttgtc aatgcaacgt ttggtccatc
     3181 agattcgata ttcgtcgtca atgcaggtac catgatgttt tgagccgtaa gcactttgga
     3241 acgatcgact tcttccacaa attcacgtac ataatcattt gctggattgg tcaatatttc
     3301 ttcacctgtt ccgatctgca tgatttcgcc gtctttcatc aaggcgattc tgtccccaat
     3361 ccgtaaagct tcattcaaat catgggtaat gaaaataatc gttttttgaa cattggcttg
     3421 caggtccagt aattcgtctt gcatttctcg ccggatcagc ggatcaagag ccgagaacgc
     3481 ttcgtccatc agcaagatct caggatcatt tgctaaagct ctggctaggc caacccgttg
     3541 ttgcatccca ccagataact gactaggata ttggtcttta aatgaaagca aactagaatt
     3601 ttctaatgct ttttctgctt tttcttgtcg ttcttcttta ggtacaccac ggacttctaa
     3661 cccgtattct gtattttcca agatcgttcg atgtggaaac agaccgaagt tttggaaaac
     3721 catattgatt ttatgacgac ggacttctcg caattcttct ttgcttaact tcgatacatc
     3781 ttctccatca atatagatac tgcccgaagt tggctcaatc agacgattca atagacggat
     3841 caatgtggat ttcccactcc cggaaagccc catgatcacg aagatttctc cttcttttac
     3901 gtcaaaattc acgtcataca caccaaccgt tgcaccggtt ttctttaaaa tctccgtttt
     3961 cggctggtga tcattcatca tatctaaagc ggcttgtgtc tttttaccaa atatctttgt
     4021 taaatgtttt acttctactt ttaccaaaca aattctcctt ttttatgtaa attcattttt
     4081 ctttctgaaa aaagtgacca cactatgtta acatcatgta gtcactttgt caaaaatgaa
     4141 agaaatttgc ttgtccaaac tgaaaaaaac ttggctaaat ctttgtaaat aaaaggttta
     4201 gccaagttaa tattttttta atatttcaca caatcattct gcaagctgat gctccgggta
     4261 aaaaaagttt gtcatacgct gtagtgtata ttcatttcca ataaaatgaa cgatgtcccc
     4321 tgccgtaaat ttagcatagg ggccaggtga aacaagcagt tcttcattat gagaaattgc
     4381 gataactgtg gcgccagtcg cctgccagat attcaactcg ctaattgaac ggtccagatg
     4441 cattgctttt tctgataaag ataattcaaa cggaagtaaa ggattcatct tatgtattcg
     4501 cttcgtttga ttgaccagct gatccaataa ttgagaaaaa tgattcagct catcttgttg
     4561 cttctccaca cttgccatga tttctgcttt tgtatcttgg atggattgta catcttgata
     4621 ttgcaatagg aaatcttttg ctttttcctt cgaagcaaca aatgccccac ttccatgccg
     4681 tacttccatg attccaagat ctaccagcac attgatagcc ttgcgggtag tctcaggaga
     4741 agcattgtac gtactggcaa gtgttgagcg ggcatggatc ttctcaccca ctttatatcg
     4801 gttttcaacg atacgttcgg ctaaatcaac agcaatctgc tggtagcgcg ggcggacgat
     4861 ttttttcttt ccagacattt tctttcctct ttcttttttt actttccctc atcttactat
     4921 gctctagcaa aataagcaaa aaaggggaga atagcctctt gcaacgactg atcatcgctt
     4981 gatctgttcc ttttttactg ggcaagctgt ttgacagtca tcacaattct taccggattt
     5041 taaacgagta tagacaattg cgcctgcact tccaaagatt aacacactta ataagaatgt
     5101 cgccatccta ttcctctcct tctaatgaca atatagtata aaactggttc ttggattttg
     5161 gctgacggaa caaaacataa acgagtccta tcatcagtaa aatagcaaga tacgtcccta
     5221 acgctacctg tccaccctcc aataagtgtc ccaactgata aatcacaaaa ctaactaaat
     5281 aagctaaacc gcattgatag cctatggcga tccaagtcca tttcttggca ttcatttccc
     5341 gatggatagc cccaattgcc gcaaaacaag gcgcacaaag taaattgaag gctaacaatg
     5401 aataagctgc tgcgggagta tatgtgtgtt gtagcacttg ccagatttct ctgccatttt
     5461 cggatacttc cgcatgacca aacaaaatac caaatgtgcc aataatattt tctttagcga
     5521 ccaatcctgt aatcgctgcg actgttcctt gccagtttcc ccaaccaagc ggctgaaaaa
     5581 caactgccag gattcgcccg aaaaaggcta agatactttg gtcttcagaa acaggttgag
     5641 cataaaaatt ataagaagag ctgaaccaga tcacgatact agaaacaaag ataatcgttc
     5701 ctgctttttt aacaaaagac ttgctgcggt cataggtttg tcttaggacc gctgaccatt
     5761 gaggaaaatg atatgcgggc aattccatga taaaaggagc tgtatctcca gcaaacaaac
     5821 gtgttttttt caagctgatt ccagagaaaa taattgcagt cataccaaga aaataggcag
     5881 aaggagctac ccaagattga tgaggaaaaa aggcccctgc tactaaggca ataatcggca
     5941 actttgcaga acaaggcatg aaggttgtga ccatgatcgt caaacgacga tcttgctcgt
     6001 tttcaatcgt gcgactggcc atgacgcctg gcactccaca tcctgtagca atcagcatag
     6061 gaatgaagga ttttcctgaa agaccgaatt tcctgaaaag tcgatccatg acaaaagcga
     6121 tcctcgccat atatccgcag tcttccagaa agctcaagca taaaaacaat ataatcaatt
     6181 gcggtagaaa tcctaacact gctcccacgc ctgcgatgat gccgttcaag atcagctcct
     6241 gcatccatcc cgctacttgc cattcagcta acaatctgcc aacatgttct ggtaaccatg
     6301 taccaaacaa tgtgtcattg atccaatctg tccccattgt tcctactgtt tgaatagcca
     6361 gataatagat cagccacatc acaaatgcga agatcggcaa ggctaaccaa cgattcgttg
     6421 caatctgatc gattttgtca ctcatcgata attggaaaga atcatttgac acaacacaga
     6481 gtgtacatag ttgggtaata aattcataac gttcattgac cagaatcgtc tcactatcgt
     6541 cgtccaatag tttctctgtt aactggatca gttgctcgat ctctttttgc tgagaaactg
     6601 ctatctcgta atcctctctt accttctgat ctcgttcaaa atatttcatt gcataccagc
     6661 gtttcttgcc gctttgttct cctagtacat cttcaatttc atgtaaagct gcttctaaac
     6721 gtggatcata tgtacaggga acaggaatag aaggccgctt ttttgcagac tcctgaatct
     6781 tttcgattag tttttcgatt ccttgctttt tcaatacgct gattggtaaa actggtacac
     6841 caagaccata ggaaagcttt tctagattga ttttttttcc ttcttttttg atgacatcca
     6901 tcatattcag accaatgatc ataggaatgt ctaaatccaa taactgcgta gttaaataaa
     6961 gatttcgttc taaattggta gcatcaataa tgttgatgat cagttcaggc tgttcctgaa
     7021 ccaaataatc tcttgcaatc acttcttctg gtgtataagg agacaaagaa tagatgccgg
     7081 gtaggtcctg aatatgaatg ttcggatttt ttttcaacga tccttctttt ttttctactg
     7141 ttacgcccgg ccaattccct acatattgat tcgaaccagt caagagattg aacaagctag
     7201 ttttcccgct gtttggattt ccgactaacg cgatattcat tctttttcct ccctttgtat
     7261 caagattagt tcggcctctg actttcgtaa cgtcagttca taccctcgca ctgtcagttc
     7321 gattggatct cccagagggg ctagttttcg gataactatt tttacatttc gcgtcaatcc
     7381 catatccatt aaccgtcgct tcactgcgcc ttgtccgtgg attgctacga cgatcccagt
     7441 ctctcctgct tttaattgat caagagaagt ccagctttca gaggaagcag tctttttatt
     7501 gacaaagatt tgacctagta tttcccgact tactgccact cgatgacttt ttaccagtaa
     7561 aatggcattg ttgcctgata aattgacgac gacgatttta cttccggcaa cgatcccgat
     7621 attttgcaaa tggcgttttg ttttttcttc tgtttcgatt cgttcgactt gataaacgaa
     7681 attctgcttt gcctgcgcta aggtctgcat attgattcct ctcttgtgaa ataaatcatg
     7741 tattaaaatc attcattata tgttctaatt ttcttacgtg ttacgcaaat aaatgagaat
     7801 cattctcaca tagaatactc tcggtaattg agaatgtcaa ttatacttgt gatattatga
     7861 gcgaatcttt agtattgata gataaaaatg agaaaaaaat atttcttcat agttttccac
     7921 aattttttct ctattaaatt tgctattttc ccacacgata cttgttttca gctctttttt
     7981 caaaaacaca aaacttagta ttccacagtt tccacaacac aatatgtagt gtttgttgtt
     8041 tgactttttt actaagagtt ttatactatc tattatagat aataagaatg tgttagagga
     8101 ggcactcacc atgaacgtaa aaatcttttc taaaaataat tgtatgcaat gtaagatggt
     8161 caaacggttt ttaacagaaa atcaaattgc ttttgaagaa gtcaatatcg atgaacagcc
     8221 tgaagcagta gactggttga aagcacaagg attccaaagt gttcctgtca ttacttctga
     8281 tgcagaaaca gttatcggat tccgtcctga tcagttgcgt aaacttgcca gctaacatga
     8341 ctaaaagaat caaaacgtga tacatggatt tgaagggctt gagacagcac cagtttttgt
     8401 cgcaaacttc caaatccttt tttaaagctt aaaaacaatg caatgatttg caatcaagca
     8461 tcatcaaata cgaaatgaag gttgggcgta cgtatgagtc ttaaaaattt acaagatgtc
     8521 agttatttca agctgaataa tgaaatcaat cggccagtca atggtcaaat ccctttgaat
     8581 aaggataaag aagctttagt tgcctttttt gaggaaaatg tcaaaccaaa tacgatgact
     8641 tttccatcta ttatggaaaa aatcaattac ttgatcgatc aagaatatat agaagcagaa
     8701 ttcattcaat tgtattcacc atcatttatt gaaaagctat atcaattttt ggacgagcaa
     8761 catttttctt tcaaatcttt tatggctgct tacaaatttt attctcaata tgcgttgaaa
     8821 accaacgacg gttccgctta tctggaaact tatgaagatc gagtagcctt caatgcgctt
     8881 tactttgcga acggggatga agaattagca cttgctcttg cagacgaaat gatccatcaa
     8941 cgatatcagc cagctacacc ttctttcttg aatgctggac gtaaacgtcg gggcgaattg
     9001 gtgtcttgtt tcttgactca agtcactgac gatatgaact ctatcgggcg ctcaatcaac
     9061 tctgctttgc aattgtcccg tattggtggc ggcgtaggga ttactttatc aaatcttcgt
     9121 gaagccggcg ctcctatcaa aggatatgag ggtgctgcaa gtggtgtcgt tccagtcatg
     9181 aaattattcg aagatagttt cagctattct aatcaattag gtcagcgtca aggagctggc
     9241 gtggtttatt tgaacgtttt ccatccagac attattgctt tcctttcagc aaaaaaagaa
     9301 aatgcagatg aaaagattcg cgtaaaaact ctttctcttg gcgtgatcgt acctgataaa
     9361 ttttatgaat tgacacgtaa aaacgaagat atgtatttat ttagtccata tagtgtcgaa
     9421 aaagaatatg gtgtcccatt ctcttatgta aatattacag ctgagtatga tcatctagtt
     9481 gcaaatccaa acattcgcaa acaaaaaatc aaagcgcgtg atcttgaaaa tgaaatctca
     9541 aaattacaac aagaatctgg ctatccttac gtaatcaata ttgatacagc gaaccgcgag
     9601 aatccaatcg atggcaagat catcatgagt aatttatgtt cagagatttt acaagttcaa
     9661 acgccttctg tgattaacgg caaacaggaa tatgaagtat taggaacaga tatctcatgt
     9721 aacttaggct cgacaaatat cgtgaatttg atgcaaagcc ctaactttgg tcaatctgtg
     9781 cgtacgatga ctcgtgcatt gacatttatt acagatgcat ctgatatcga tgtcgtacca
     9841 ccgatccaaa acggaaataa gctgaatcat acgattggat taggtgccat gggcttacac
     9901 acttatcttg caaaagaaca aatggaatat ggctcagagg attcattaga ctttacaaat
     9961 atttacttca tgctgttgaa ttattggaca cttgttgaaa gcaacaatat cgctcgtgaa
    10021 agaaaacaag ttttccataa ttttgaaaaa tcagcttatg ctgacggcac ttatttcgaa
    10081 aaatacgtaa ctggagaatt ccagccaaaa tcagaaaaag tcaaagcatt gtttgaaggc
    10141 atttttatcc caactgctga agattggaat gctttgaaac aagcagtaat gaaagatgga
    10201 ctgtatcatc aaaatcgctt ggcagtagca ccaaatggct caatttcata tatcaacgat
    10261 acgagtgcaa gtattcatcc tatcactcgc atgatcgaag aacgccaaga gaagaaaatc
    10321 ggtaaaattt attacccagc gccttatcta tccaatgaga cgattccgta ttacacttct
    10381 gcttatgata tggacatgcg taaagtaatc gatgtttatg caacggcaca acaacacgtc
    10441 gatcaaggca tgagtttgac tttattcatg cgttctgaaa tcccagaagg catttatgaa
    10501 tggaagacaa caacgaagca aacgacacgt gatttgaata ttttaagaca ttacgctttc
    10561 cacaaaggaa tcaaatccat ttattacgta cgtaccttta ctgatgatgc agaagaaatc
    10621 ggaagcaatc aatgtgaaag ctgcgtgatc taatatcata gatagattcg cttattcata
    10681 ttttaattaa aggagcattc tcatgtcaga aacatattat gaagcaataa actggaatga
    10741 aattgaagat atcattgata aatccacttg ggagaagctg acagagcaat tttggctaga
    10801 tacacgtatc ccactttcaa atgacctaga tgattggcgt acattgtctc aattggaaaa
    10861 agatacagta ggacatgtat ttggcggttt gacactgcta gatactgtcc aatctgaaag
    10921 tggcatggat cagttgcgta aagatgtccg cactccccat gaagaagccg ttttgaacaa
    10981 tattcaattc atggaatccg ttcatgccaa aagttattct tctattttta gtacactgaa
    11041 tacgaaaaaa gaaatcgaag aaatttttga ctggacaaat acgaatcctt atctgcaaaa
    11101 aaaagctgag cgtatcaatg aaatctacaa acacggtaca ccgctagaaa agaaaattgc
    11161 cagcgtcttt ttagaaacat tcttgttcta ttcaggtttt tatactcctc tttattattt
    11221 aggaaacaac aaattggcta acgtagcaga gatcatcaaa ctaatcatcc gagatgaatc
    11281 tgtacatgga acctacatcg gttacaaatt ccaattagga ttcaacgagt tacctgaagc
    11341 agaacaagaa acgttaaaag actggatgta caatcttctt tatgagcttt acgaaaacga
    11401 agaacgttat acagaagaat tatacgatcc aatcggctgg acagaagaag tcaagacatt
    11461 cctacgctat aatgccaaca aagcattgat gaacctaggg atggatccac tctttccaga
    11521 tactgccaat gatgtcaacc caatcgtaat gaacgggatt tcaacaggca caagcaacca
    11581 tgacttcttc tcacaagtcg gaaacggcta tttgttaggt catgtagaag cgatgaaaga
    11641 cgacgattat ttgattggat tggaataagg atttatttta attcaaaaat ttttcgaaaa
    11701 ataaaaagag tttagcgtac agatatttta aatgtacact gaactctttt ttatgcttat
    11761 tcacttgttt cttccagcac ttttggactg tctaactttt ccgaaacatg ttccattctt
    11821 ctcaataaat agattttccg gatatttaat attatcgtct taatcactgc atagacaggt
    11881 atgcaaatca gcatgcctaa tattcctgcg acacttcctg ctccaatcaa taccaagatg
    11941 atcgtcaaag gatggatatt cattgatttc ccaaataaca acggcttgat caaatttcca
    12001 tctaattgtt ggatcactaa aatcgacaac gccatataca aagcttgaaa tggagagata
    12061 aacaaaccga caatgattgc tggtaccgct ccaataaaag ggccgacata cgggataata
    12121 ttcgtgattc cgcaaatgac cgcaagcaac aagctataag gctgatcgaa tattctcatt
    12181 gccaaaaagc tcattacacc aataatcaaa gcatctaaga tcgtactgct gatataggca
    12241 gataatgttt cgtttaattc ttttaccgtt tggcgtaact ctttacgaat cgctttcgga
    12301 aagaagtgag acaacgcatc aataaatttg tgcccatcct tgaacataaa tagcaaaata
    12361 aatggaacgg taaataacaa aataaaaaat tgcatcataa atgaaatgat ttttgagaca
    12421 cttgcagata aactgactaa tatgatattg aacaaattac taagagataa atttgctgat
    12481 gctaattgtt cttccaaatt gaaattttta aactcttccc gctgcgccaa ttcatttaac
    12541 catttgcttg tttcatctgc atacattggc aagctctggg tcaattgaat tgtctgttcc
    12601 attaactgag gcactacatt catgacagtt aaaacaacta aaatgattac gaccaaaaac
    12661 gtcaataaaa aaccgaacac tctcgggatc cgatgctttt cgagaaaaac aacgattgga
    12721 tcgaacatat aatagataaa accagcaaca agcaatggta aaaaaattgc cgaaagcatt
    12781 ttcaatattg gactaaaaat attcggcatt tgtaaaataa agtacacgcc gatgatcgtg
    12841 agtactagct ccactgtcca gaaaaataat tttgattgtt taaaacgtga ttgcatacat
    12901 ctcctccaag gtcctttgat acttctattc tatcatttaa caaagagtta cgcgctgaga
    12961 ttttcatttg cttaaaaaaa acaaaaaaaa taaacatatt ttaatgagta gacgagtact
    13021 taaacaaaaa cacggtttgg agtagtgaca aaaattatac tgcagtccct ttttccaaat
    13081 aaacggtgtt caaaagcttg catcttcgta ataagcccag ccaaacgaaa aatataagga
    13141 actattttta tttggctggg cttattactt gatgtaggac atctatttta caacctcaga
    13201 tcatttattg cgcaatactg actaaatgca actttgtgat atttttgtgt acggacaact
    13261 cctcgatcac atcggcataa gtgagccctt ttggaagatc aatcgtatag atatttttgt
    13321 acactcggta gtcatcaacg aattttacgt caaaattcac atcttcgatt acgatatttt
    13381 tctcttcaaa ataatcggta agaaaatctt tggtttcttt tctatggata aattggattt
    13441 ctaacttttt agtcgtaggt acatggatca cgcgtttcac tactgtgagt gcaatagcaa
    13501 tcccgataaa actgatgatc gcaatggaat agtaacccat gccgatggcg atccctaatc
    13561 cagcaattgc ccataaagaa gcggcagtcg taagtcccgt caccgattgt ttcgtgacga
    13621 tgatcgttcc cgcgcctaag aaaccgacac cactcaccac ttgagcaatc agccttgctt
    13681 catctgaacg aatcgttcca gcaagctgtg gatactctaa agcatctctt aatgcaccac
    13741 tagcgatctc aacttggatc aatgcaatga tacatgctcc catacaaact aaaatatgcg
    13801 tacgcatacc tgctggacga tttttatatt gtcgttcaaa accgattgct ccgccaaata
    13861 gcatagcgat ccctaaacgt aaaataatct ctggaattgt caataccata tcattcatct
    13921 aaacaccctc cagtccaata tatcatgtct gaaaggagca gacaaaaaaa gtgcaatttt
    13981 tacctcttac gaaaaaagga ctgtgacaaa atttttgtca tagtcctttt tatgaataaa
    14041 cggtgttcaa tcagctgacc ctcggtatta ctcaacaaac ggcaaaatat ggggagctat
    14101 ttttcctttg tcttctctaa tactcaggtc aaaacgctga tttcacaacc tctttagcct
    14161 actattgaaa attacaactt acttgctgct tcttcatcga tgatcacaac aacattgtcg
    14221 tgattttgca atacacttgc tggcaaatga ttcgttacag gtccttcaat catccctttg
    14281 attgcatcag ctttgctttc gccaaatgcc atcaagacga tttctttact tttcataatt
    14341 gaaccgattc ccattgaaac agcttttgtt ggtacatctt ctgctttatc gaagaatcgt
    14401 ttgtttgcat tgattgttga ttctgttaag tcaactactg aagtcgttcc gtcaaatgaa
    14461 gcaccaggtt cattgaaacc gatatgtcca ttttgcccga ttcctaagat ttggatatcg
    14521 attggatgtg catcgatgat ttgatcatac tttttgcatg ctgcttccag atcttctgct
    14581 tttccatctg gtacaaacgt ttctttgaat ggttttttat caaataattg gacatccatg
    14641 aaatgacggt agctttgttc atctgaaccg cctagtccaa cgtactcatc taagtttaca
    14701 gaagtcattt cactgaaatc caaatcgctt gaagtcattt ctttatataa agtaactggt
    14761 gtgcttcctg ttgccaatcc taatactttt gcacctttgt tcataccttc tttgatgatt
    14821 tcaaatgctt tttttccgcc ttcttcagcg ttttttacac gaatgatttc catagtgatt
    14881 gctcctttat attttggtat agcccaatta tagcattctt tttttctttt tacaataatt
    14941 agtatagacc aaattgcatt tttttcattt tcttgacaat aaataggaat ccgtgttagg
    15001 tttcataaga tggttcaatc aaacaatcca tgttgcatga aaaccaagca agtgattcac
    15061 tgtggacgct ttatgtctgc agttttttta tgaaaaagga gttattatga gtatactgac
    15121 attaaacaac attacccagc aatttggcga caaaatcctc tatgaaggtg tcgatctgca
    15181 attaaatgct ggcgaacatc ttgggctgat tggacaaaac ggagccggta aaagtacatt
    15241 gattaaaatc atcactggtg agatcttacc agatgacgga cagatccatt ggcaaaaaaa
    15301 tattcacaaa ggttacctcg atcaatatgt ggaagtcgat gaaacattaa caatcgaaga
    15361 atttctaaaa actgcgtacg caaaagaata cgaaaaggaa gaaaaaattg cttttcttta
    15421 ccaaacatat agcgagacct tcgatgattc cttgctggaa aaagctggga aactccaaac
    15481 ggaattagac caaggagtgt tttatcaaat cgacacctta gttgctgaga tgagcagcgg
    15541 gttggggatc gatgtcttag gtttagattc actgttgaaa aatctaagtg gtggacaacg
    15601 ttcaaaggtg attttagcaa aactactttt agaaaaccca gatgttctga tcttagatga
    15661 accaaccaat cacttagatg atcagcatat ccaatggctg acgcagtttc ttcaggattt
    15721 tgacggtgcg tatatcgtga tttcccatga ccaagaattt cttgatcaga tcaccaccca
    15781 tatcgcagac atcgagtttg gaaagattac taagtatact ggccatctaa aacaagcatt
    15841 gaaacaaaag gaacaaaatc gcgaaagcta tttgcgccaa tatcatgctc aacaaaaaca
    15901 aatcgaaaag accgaagctt atattcgaaa atacaaagcc ggttcccgat caacgatggc
    15961 aaaaagccga caaaaacaat tagataaaat cgaacggctg acgcctccag cttcagcaag
    16021 taaagctgtc tttgattttc cattctcgcc tattgtcacg acattagcag tggaaacaac
    16081 tgatttagtc atcggatatg atcgaccgct acttgcaccc atcaatttga ccatccgctt
    16141 tggtgaaaat attgccattc gaggcttcaa cgggattgga aaatctactt tattaaaaac
    16201 actgatcggt gagattgaaa aaataagtgg cgatttccac ttcccagata acacaaaaat
    16261 caattacttt tcacaagatc tgtactggga aaatccatta gaaacaccac tacaatattt
    16321 aagcagtcaa tttccaaaag cgactatcaa agaattacgt cgccaactag ctaaagcagg
    16381 gttagttaat caattagcaa gtgaacctct cactacatta agtggtgggg aacaaactaa
    16441 ggtgaaactt gcacagttga caatgaacca aggtaattta ctgattctcg atgaaccgac
    16501 gaaccatatc gatcaagaaa cgaaagaaag cttacaagac gggatacaga aatttccagg
    16561 aacagtaatc atcgtctctc atgaacaaga attttatcaa gatcttgtgc aacgagtcat
    16621 tgagattgaa ccaaaataaa cgtttgattg aatagttgaa aaaaaggagc tgtgacaaaa
    16681 gttttgtcac aactccttct tctgaataaa tggtggccaa ttagctgacc ttcggtatta
    16741 gctcaaaaaa cggcaaaata tgaggagcta tttttatttg gctattctta ttacttgatg
    16801 cagaacagct tttcacaacc tcttttcgtc tattttttat tttcgagatt tctctttcct
    16861 ttaaaaacaa ctgtttgaaa gaagaacgca catccttgaa aaacaagccc gctaaccgtt
    16921 acacctaacc agccatactg ctgccacatt gtcgtcccta gcaatgaacc agccgcacct
    16981 ccaataaagt acataaacat aaataca
//
LOCUS       DAPBBV010000053        16876 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.053, whole genome shotgun sequence.
ACCESSION   DAPBBV010000053 DAPBBV010000000
VERSION     DAPBBV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.053"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..587)
                     /locus_tag="RD486_002327"
     CDS             complement(<1..587)
                     /locus_tag="RD486_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664043.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVF"
     gene            complement(735..1277)
                     /locus_tag="RD486_002328"
     CDS             complement(735..1277)
                     /locus_tag="RD486_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HDT7664044.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            1412..1801
                     /locus_tag="RD486_002329"
     CDS             1412..1801
                     /locus_tag="RD486_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664045.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1805..2569
                     /locus_tag="RD486_002330"
     CDS             1805..2569
                     /locus_tag="RD486_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7664046.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2698..3645
                     /locus_tag="RD486_002331"
     CDS             2698..3645
                     /locus_tag="RD486_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7664047.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3775..4515
                     /locus_tag="RD486_002332"
     CDS             3775..4515
                     /locus_tag="RD486_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664048.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4806..5474)
                     /locus_tag="RD486_002333"
     CDS             complement(4806..5474)
                     /locus_tag="RD486_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7664049.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            5608..5895
                     /locus_tag="RD486_002334"
     CDS             5608..5895
                     /locus_tag="RD486_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664050.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            6311..7849
                     /locus_tag="RD486_002335"
     CDS             6311..7849
                     /locus_tag="RD486_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HDT7664051.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7846..8811
                     /locus_tag="RD486_002336"
     CDS             7846..8811
                     /locus_tag="RD486_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7664052.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8798..10120
                     /locus_tag="RD486_002337"
     CDS             8798..10120
                     /locus_tag="RD486_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7664053.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTPVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      10183..10287
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10361..11104
                     /locus_tag="RD486_002338"
     CDS             10361..11104
                     /locus_tag="RD486_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7664054.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            11119..12111
                     /locus_tag="RD486_002339"
     CDS             11119..12111
                     /locus_tag="RD486_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7664055.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            12123..12860
                     /locus_tag="RD486_002340"
     CDS             12123..12860
                     /locus_tag="RD486_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7664056.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12850..13572
                     /locus_tag="RD486_002341"
     CDS             12850..13572
                     /locus_tag="RD486_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDT7664057.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(13656..14279)
                     /locus_tag="RD486_002342"
     CDS             complement(13656..14279)
                     /locus_tag="RD486_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7664058.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            14674..15365
                     /locus_tag="RD486_002343"
                     /pseudo
     CDS             14674..15365
                     /locus_tag="RD486_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            15573..15863
                     /locus_tag="RD486_002344"
     CDS             15573..15863
                     /locus_tag="RD486_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664059.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         5765 a         2786 c         3432 g         4893 t
ORIGIN      
        1 ataaatacac ctagactgac gatgaagagc atatccaaca gatttcctgc gacttggatc
       61 gtcgaagggt tggtcagtgg cattaaagca aggacaaaaa aggaaaacaa gctgtaaata
      121 aaacaggtga caggaactaa tcgaaagaag agcggacatt tcaattggct aaaaatgagt
      181 gaaaaaataa aataagtaaa aatggataaa atcacgacta aaccattcat gataaagaag
      241 aaaagcgtat tgtgattaaa cgaataaaaa agaattgcta aaaaagaaaa cgttttaaat
      301 gcaatcaata cgcttgaagc ttcgtttaac gtaccaggat gtcgatgaaa aaaataggca
      361 ccgaaataaa cagaaaacag taagccgcaa agagaagaca aaatcaaaaa aaacggattt
      421 tcttcggctt ctgtgatatc agaatgatcc aaaagcaacc agcctaatgc actagaaggc
      481 gcatgtgagg tcttaaggta tgaataacat agaaaaaata agatcgtcaa agttgcaaaa
      541 aaagagccta aatgtaaaaa attagtggtt ctacgttgaa tttccataat atctccaaat
      601 taaattgata agtatataaa gtataataac aaattgatga gtatatgtcg atgtttttta
      661 atcaaaataa taaataaaaa ctgtctaaca tttaaaattt aatttagata ttagacagtt
      721 tttaagtttg tgagttattt tccttgtcgt tttctcactt ttttagtcca gaaaccacct
      781 gaaatatatt ttggctcata agaaatgata aaagcacgct cttcgatttc tttgatcagg
      841 cgatacagtt cacgttcgct ttttctagga gaaagtattt cgagaactag ccgctcacct
      901 tccagcccca ttgcagaagt ctgtgtcaca ccataaccgt gttctctcag tatacccggc
      961 aaacttttat cttctgcgct atttgctggc aaaatcgttg tgaccatgat gtatcctaat
     1021 gccaatttgt cttcaatcaa aattccgaca ctgataccta ctgcgtaacc taacgcatag
     1081 acaaataaat tcagtggatt atctaaacga tctaaaacaa gggataagcc gacgatataa
     1141 atcgtgatct cgaccatact gacaagtgga gcaatcagtc gatagccttt cattgtcaac
     1201 atgaaacgta acgtgttcag agtgatataa gcaaaattaa tgaggaagat catccccaac
     1261 atttttggat caatcatttg taaaactcct ttcatttata taacaacaat atcaaaaaaa
     1321 atcgtaagtg aagaaaaatt gaaactttat acatacaaaa aaatgataaa atgattataa
     1381 tagaattata aagataggtt aggtgattaa aatgaaaacg gtcaatcgtg tgttttgtgc
     1441 cagccacgtg ctaagtctcc ttctcagtat atacttaggt gtctattcga ttcaacagcc
     1501 aattgaggta gagaacattg tttttcagat gtcgctgaca gatggtttaa ttttaagcgt
     1561 ttttttcttt ttgatactgt ttattggtaa tattttcggt agcgttgcca gttttttgaa
     1621 tttttctatt tatccactcc tttcgctagc attaggagtg gtgggacttt gttctctgtg
     1681 cttatttccc gagccattca gtcctgcatt tatattattt ggtacactga acctgttcca
     1741 gacaactgtt ggagcatggt tgctatggcg atcaggaaat ttaatgaaaa taggtgagta
     1801 acaattgaat ccaattatat tgaaacgttc tgtccatcat attccagtgt tagaagttgt
     1861 tctgaaagaa ttaagagagg aacgtattcc cgttgtcatc tattatcacg gatggcagac
     1921 aagtaaggag ttagttttga cgcaaggaag aaaaattgcg cagcagggca ttcgtgtgat
     1981 cctgccagat gcgatgaatc atggggagcg caaacagccg gtttcttcta ttccatccta
     2041 tacattttgg gatagtatct acggaaatct gtttgaattt gacacactta tcaagcattt
     2101 agaaaaaaga ggtcttctac atgatcagct tgcagttggc ggggtttcga tggggggaat
     2161 gacaacatgc gccttgttgg ctaaacatcc tcatatagta gcgggcgtgt gtttgatggg
     2221 ttcccctgca cctttggaat atggaaaaga aatcgtaagg cgcgcatcgg aatataatta
     2281 tgtcgtacca aaagactatt ttgatttgat ttcatgggtt aagagctatg atttgtcatt
     2341 gcagccggaa aagttagctg gacgtcctct gttcttttgg catggacaag ctgacgaaaa
     2401 aatcccttat atacaaacgg aacgatttgt agaaaaaaat cggcataagt cttacggaaa
     2461 agaaattgtt tttcgttcct caaaaacaca gcgacatatg gtacaaatac cactaatgga
     2521 agaagcttcc acttttttag caaaaaattt gataaaaaag tataaataat tgaaacggaa
     2581 aatcactcat gacgatagag gattttccgt tttttatttt gggctataat aaactctgtt
     2641 aggaaaattt ggtataattg atagtaagaa tgacaacatg ttagaaagga agagagcatg
     2701 cccactttag cagatgttgc aaaacgtgcc aatgtttcaa aaatgacggt ctctcgagtc
     2761 atcaatcatc cggaacaggt gactgacgaa ttgaaagagt tagttttctc agcaatggct
     2821 gaactggatt accgtccaaa tattgctgca aaagcacttg tcacgaatcg gtcgcagatc
     2881 atcaaattat ttatactgga agaaatcgac acaactgagc cctattacat gaatttgctg
     2941 atgggaatcg ctaaacggat cggtaaagcg cattattctc tccaattagt tacaaatgat
     3001 gccttcgacg tcggttcttg tgatggatac atcatcacag gtgtcagaaa aaaagacttc
     3061 gattggatcg accgtttgga aaaaccagtt gtcttgtttg gggaaaattc tgaaggatat
     3121 gattatgtag acagcgataa tgaatatggt acagcaaaag caacgcaata tgccttagaa
     3181 agagattatc aaacgattat ttatatcggt atcgaagtgg acgagccttt tgaaatttca
     3241 agggaaactg gttatttatc tgtgatgaag gaagttgatc ttcctagtaa aatcttgcgg
     3301 tttccaaatc attcgacaga agtagaaaga tatatgacag aaaactgggc agattttaca
     3361 gataaaactt gttttgtatg tagttcagat cggctagcac taggagcagt aagagggatt
     3421 ataaatgctg gaggacactt gcccgaagaa tttggtgtga ttggatttga tggggtattt
     3481 ttagaccaaa tcagttcacc taaattgaca acgatcaagc aagatattat acgtatgggt
     3541 gaagtatgtg gagaaatgtt gttaaaaaaa atagaagaaa aaggggcgag tcaaggttat
     3601 cgtcgttttt ttcctgaact agttatcaga gagacaacga attaagtctt attactatat
     3661 atatatttat gaaattcatc gctattttct taaaataatc agcgcattgc tactgaaaac
     3721 aatgaatctg tgctattatt gagaaaagtt ccatttttga gaaggatggt ttgaatgaaa
     3781 gaaatcagac gaaaacattt ccgttttcct gcgtacgatg atgagttagg cgtaaaatta
     3841 accaacgaca agaagcgagt attatttgac ggacaagaag atcttttgac tgaacagaat
     3901 cagtccccgt ttgaacagat gaaagaattt catttcacga acacgaacac cgagaaaatc
     3961 cgtcgcaagc gtcgtgcaac aaatggattg aagtcagctc cgcgtaagga aaatttggaa
     4021 aagcataaag gaaaattacc ggattatacc ggccattacc aatcagaaat cacatcgaca
     4081 ggacgaaaaa aactttttgg tgattcctct cgttctgtca gacaaagtga aacaaggaca
     4141 gagtccaagc atactacacg aaacgcatct gttgacacga aggtgcggga gcgttcttat
     4201 tttgttccta aatatgtacc cgcatcgatt atcccagacc ctagagaaag caaaatttct
     4261 gaggatcatt taatcgaatc gatgaaaaaa acggatgact cttatctgtt gttcgataca
     4321 gaaccgacgc cgtatcaaga aaaaagaaat ggtgagccgt ctgtacgaac attcaatcga
     4381 acaaaaacgt tagaggaaac aaagcagtca gaagaaaaaa aatcgaaaaa aagccatggt
     4441 atcttagaac gctcattaca aggattgatc gatgatcaag gaaactcttt gggagaaaat
     4501 agctatttta aataagtgat atacaaattt atattcggct acagttggaa aggaaacgct
     4561 gcggcgtttc cttattttat actctatccg aaagtttata tcgtatcctc aaattttttt
     4621 gagtttaagc gaattttttc tcccaataag taagaaaata atggcaaaat aaaaaaacaa
     4681 actattttcg cagatcgttt gcaaaaatag tttatttttt tataaagaag attttactga
     4741 ataatatcat tttagtttac ataatgatat ttctgtaaat taaataaagt agtgaaaaat
     4801 aagaatcagt gctctaactg ttcaagagga tcaagtggtt caaatgtttc tgtagtctgt
     4861 tttgcttcca attggggcaa aacagatcca atttccagat acttcacttt attcaatgta
     4921 taagatagaa tagaacagct aagtaatgta tacagaaaat gtgtgagatc caaataaagc
     4981 aaggagacaa ctaaaatacc aaaagtaatc aagaaaagac ttttgccaat cttaatatga
     5041 aaatattttt caatggcttg ataaatgata tctgttccgc ctgtgcttcc gccgaatcga
     5101 aagacgagac cgcaaccaat gccagaaaga atacctgtca tcaaactatt gatcagtaga
     5161 ctatctacag caaaatgtat atgaaggctc tcccataaat gtaaaaagaa aactagcgca
     5221 aatgttccga cgatcgtccg gagaaaagcg tgttttccaa aaagaaacaa tgagataagc
     5281 aataaaggta aattaaaaag cagtgaagtg acagaaggag cgaatccaaa aagattatgc
     5341 aaaagcaaag caataccagt aaccccacca tctgccagct tagatggaat attgattcct
     5401 gtcacagcta atccgtagat tcctgcgcct aaaatgattc cgcacaattc tgtaaataaa
     5461 tttaattttt tcatttctag cctcttttct tttgaaaatt ttcagcaact tctttattat
     5521 actgacttat actcttactt caagaggaaa atgaaaaaaa attatttttg gctgtttctt
     5581 tttatttatc aaataaggag tggaaaaatg cgagcagcag acttattgac aattcttaca
     5641 aaatcaccca aaaaaacaga gtatcaagga gtttttttgg ctcaagaaca aaaactggtg
     5701 cctgtgacaa tggtccagat aaataaagca aatcaattta tctttttatt tgaacacggc
     5761 aaagcaccac ttgctatgaa agacatcttt ctttttttga tgaagaaccg tgagaaagct
     5821 gtttattatc agtcaaaaga agaactcatt cctctttatg gagtgaaaga gatagaaaat
     5881 aaagtggtga tataagtaaa aataagaaaa caagacgttt atgatgtcaa aacaaccatt
     5941 ttttacattt ttggcaaaaa agtgtcatga tacagtataa tattcgttga acaggccaat
     6001 aaaggtgttc tcccccacga gatttctact ttattggctg tttcttttta ttaaaataaa
     6061 agttgtgtgt gtaaaaaaga tatagctgat tccaagtgac aatttcgtat agatttttat
     6121 ggtattcgta gtgaaaaaac gagaaccaaa aagttgatcc gactttgttg cttggattct
     6181 ttttttgtca gcatatttag aggtattttt ttcttttttt tgttcgtgct gtaaggttaa
     6241 ggcaagacaa gttagttggg aaaaaggaaa gaaatgttta tacttaaaga ataacagaaa
     6301 ggaaggtcgc atgaataatt ttatacaaac attaagtgaa agaaaaggcg agttgctgga
     6361 agctgcattt caacatctgt ccatttctct catttctttg ctgattgcag cactgattgc
     6421 tattccttta gcgatttggg cagccaatca taaaaaaatg gcagaagtct tattgcagat
     6481 cacgggtgtg ctccaaacga ttccttcact tgccttatta ggtttactta tcccatttgt
     6541 agggatcgga actgttccag cattgattgc acttgttatt tacgctttgc ttccgatttt
     6601 ccaaaacacg tatattggtc tagctgaaat tgacccgtct attgaagaag cagcggtagc
     6661 atttggtatg tccagaatga gacgcttgct gaaagtagag cttcccatcg cattacctgt
     6721 cattatctca ggtatccgaa ctgccttagt tttaatcatc ggtacggcta ctttggcagc
     6781 attgatcgga gcaggtggat tagggacatt tattttgtta ggtattgacc gaaatacacc
     6841 tgttttgaca ttgattggtg cgatcagttc tgccttgctt gcaattatat tcagcggact
     6901 gattcgctgg ttgcagcata agaaacctcg atattccatc attactttag cagcagtggt
     6961 gtgtttattt ggcggcgttt ctttatatca gtctgccttg tttaaaaatg aaaccatcac
     7021 gattgctgga aaattaggag cggaacctga aatcctgatc caaatgtata aagaattgat
     7081 tgaagacaac acaaaaacag aagttgaatt aaaaccgaat tttggcaaga cgagtttttt
     7141 gttcaatgca ctggatcaag gtcaaatcga tatctatcct gagttcacag gtactgtcct
     7201 agaaagcttg gtgaaggtac ctgaagcaat gaaaagtgct gatttgacaa aagaaaaaac
     7261 atatgacgaa gcagaagaat tattgaataa gcaattcgat atgacattat taaaaccaat
     7321 ggcttaccaa aatacgtatg ccttggcagt caagagatct tttgcgaacg aacatcaact
     7381 taaaaagatt tccgatttgg cagctatctc tgatcagatc aaagcgggat tcacactgga
     7441 atttattgat cgttcagatg gatataaagg aatccaagaa gcatatggct tgaatttttc
     7501 aagtgtacaa agcatggagc caagtttgcg ttaccaagca atcaataatg gagatgtcaa
     7561 tattgtggat gcctattcca cagatagcca gctcaaggag tacgatctag tgactctaga
     7621 agatgatcga gggttattcc cagcttatca aggcgcaccg ctgatgaaaa aagattttgc
     7681 taaagaacat cctgaaatcg ttaaagcact gaataaatta agcggaaaaa taacagagga
     7741 tcaaatgatt gatatgaatt accaagtcaa tgtcgaaaag aaaaagccga cagaagtagc
     7801 acgaatcttc ctgaaaaatg aaggattagt aaaggaggaa gatcagtgac taaattaatc
     7861 gagttcaaac atgtgcaaaa aaagtatgat ggaaagtatg tcatcgatga cctaaatctg
     7921 gcaatcaaaa aaggagaaat ctttgttttg gttggtcctt ccggtagtgg aaaaacaact
     7981 actttgaaaa tgatcaatgg attatctaaa ccatcagcag gagacatcta cttcaaagga
     8041 aaatcgttaa atgaatataa tctgcagaaa atgcggtgga atatgggata tgtgctgcag
     8101 caaatcgctt tgttcccgac catgacagtc aagcaaaata ttgaagtcat ccctgaaatg
     8161 ttaggttggg aaaagcagaa aagagcagac cgtgtagatg aacttcttca aaaagttggc
     8221 ttatctcctg atatttatcg agatcgtatg cctagagagt tgtctggagg agaacagcaa
     8281 cggatcggga tcatccgagc tattgctgca agcccagatg tgattttgat ggacgagcca
     8341 tttagcgcat tagatccgat ttcaagaaac tcattacaag aattggtttt gtccttacac
     8401 gaagaattgg gcacgaccat cgttttcgtt acgcacaata tggaagaagc aatcaagcta
     8461 ggtgatcgta ttgcatttat gaaggatgga gaaattatcc aatgtgacac accagagcag
     8521 ttattgatga atcctaaaaa cgactacgtt cggcatttct ttgatgaacc gaaacagacg
     8581 aaagagtggc gagtagaaga tttagtcgtc aatggatatt tcttaaatga aataccagaa
     8641 aatgctcgtc aacaagtttg ctttgatacg cctatgaaag aagtatattc gcttctttcg
     8701 gtgtatccaa gcattgtgat agtagaaaag caaagaagta ttgggtcgct gacaagtaaa
     8761 gaaatctttg cttttttaag tcgagaggag gaaggaaatg aaaacatatg atgcaatcat
     8821 catcggttca ggtgtgagcg gcttaagtgc tgcttatgga ttgaaagaag caggtaaaac
     8881 agtactagtg gtcgaagaag atctatgggg cgggacttgt cctaaccgtg gatgtgatcc
     8941 taaaaaagtc ttgttaagtg cagtagaggc acgtaatcgg gtaaaacaat tgagtggaaa
     9001 aggttttaac gagatcccaa ctgccaactg ggaagaactt caaaaattca aacgaacatt
     9061 tacggatcca gtcccagaaa gccgaaaaaa acaattagca gaagctgaaa tcgatcatct
     9121 ttcaggaacc gctcgttttt tggatgattc atctattgaa gtcaacgaag aagtcttcca
     9181 tgcggattac ttagttttgg caaccgggca aagacctacg atcttaccag tggagggaaa
     9241 ggaatacttg aaaactagtg cagacttttt atcattgcct gtactgccta aagaaatcat
     9301 ttttatcggt ggtggttata ttgcttttga gctagctacg attgccaatg ctgcagggag
     9361 caaagtaacc attgtccatc ataatcaacg gccattaaaa gaatttgagg cgtctttggt
     9421 agaggaagcc gtccatcaaa tggaagcatc tggcattcag tttgcttttg gtgttgaaac
     9481 ccaaaagatc atttcagaag gtactcgcta tcgtttagtc ggaaaagaga cggaattagt
     9541 agcagatatg attttttgtg cgactgggag acagccgaat acagaatctt tagcacttga
     9601 gcaagcgaat atcgtctttg ataaacacgg aattgcagtc aatgattatc tgcaaacgag
     9661 caatccaaaa atttttgcgt gtggagatat tgtttcaagg aaaaccccaa aattgacacc
     9721 agtcgccact tttgaaggaa attatgtagc taagcggata acggatgcaa caagcgaacc
     9781 tatcaaatat ccgattatac ctacgatcgt ctacgccagt cctaaacttg ctgaagtagg
     9841 agttacaaaa agtcacgcct cttcgtcaga tcaagtggta gagatggatc ttaccagttg
     9901 gttcacctat catcgtgtca atgaaccagt tgctaaggct gaattgacct ttgaccagca
     9961 aaattatttg attggtgctg cagtgattag cgagcaagca gacgaattga tcgatgattt
    10021 gacacccgtc atcaatcaaa aattgactaa aaaagagttg gatagctata tcatggggta
    10081 tccgacattg gcaagtgatc tctcctattt attgaaataa tcagcatgat aactaaagcg
    10141 cttgttgctt tttccttctt gtgctacact ttaaaaaatg aatacctgtt tctggggatg
    10201 tcgtagacga catgagagta agttgtgaac ttagacccat tgaacctgtc agttaatact
    10261 ggtgaaggga gaaacatagc agacgcttga agcgggttac tatgtcgtgc ccatttcaag
    10321 cgttttttgt tattcatatt agaagaaagg aggtaacaaa atgaagaaaa atctttatcc
    10381 agcagtcagt atggcattca ttttaattat ttggcagatt gttgtcatag tttggaaaat
    10441 acctgccttt attttacccg gacctgctgc tgtattttct gcattagcgg cagatgcaca
    10501 agtattactt tcccattctg tcacgacatt aaatgaagca gtgcttggtt tggtaatagc
    10561 tagcgttctt tcttttatta ctgccttggc aatggattat tggaagtttt tagaaatgtc
    10621 tttttatccg ttactagtga tttcacaaat gttgccaatc atggtgttag ggccattact
    10681 taccctatgg tttggtttcg gtatgcttcc aaaagtgatc cttgttgtct tgataagcta
    10741 ttttccgatc gtagtttctt tttcggatac attgaggaaa gtatcaaaag agcaaatcat
    10801 ctttttgaaa acgatggggg cagatacagg gaagatttat cgaatatata aaataccagc
    10861 gggtttatcc ggcttctttt ccggtttaaa agtggctgct acttattgtg tcagcggagc
    10921 agtcgttgga gaatggctaa gcgctcaagc aggcttaggg tattacatga tacgcgtaaa
    10981 aaacagctac cagatcgata aagtttttgc tgcgatcatt tgtgtcattc tattgagttt
    11041 attgctgaat ggcgcttgtt cattattgaa aaaagggtat tatcgtatgc tttatatttt
    11101 ttaagagaag gggatcaaat gaaaaaatta tggcttttat taccgctact gttgctttta
    11161 tccgcttgtg gcactgcaaa agaaacaagt agcaaacaag aaataaagga tttgaaaaaa
    11221 gtgacacttg ttttggatta tgtaccgaat actaatcata ctggcatcta cctagcaaaa
    11281 gaaaaaggct attataaaga ggctggttta aatgtccaaa tcatcgaacc aggagataat
    11341 tcgacaagta ttggtctagt aggtgcggac aaagcacaat ttggtgtaag ttatcaagaa
    11401 gatgtcactt atgctcacgc agatggacag aatataccag tcaaagcaat tgctacagtg
    11461 atcaaacata atacttctgg attcgccacc ctatcagaca gtaacatcca ttcaccaaaa
    11521 gattttgaag gaaaaacata tgcaggttgg caaagtccaa gtgaagaagc tgtcttaaaa
    11581 gctgtgatgg aaaaagacgg cggggacttt tcaaaactga caatggtagg aagcaatgga
    11641 gaagggccag aaagcttagg aaaatcctca gatatccaat ggtactttga aggttgggat
    11701 atgatcaaag caaaagaagc gggtattgaa ctaaactata tcccattgaa agaattagat
    11761 gaacggttag attactatac tccggtaatt attacgaatg atcaactgat caaaagtgat
    11821 ccagaattgg tacagtcttt tatggatgcc acgaaaaaag gctatcagga agctattaag
    11881 gatccaaatg acagtgctaa actgttgcaa aaatatgcaa aagaaaatga tcggacgttt
    11941 ttagaagaat cacaagcatt cttgtcaaaa aattatacgg atgatcctga gaattgggga
    12001 ttgatggaag aaaaagtttg gcgcaattat acagctttta tgcaggaaaa cggattgatc
    12061 aagcaagatg taccttcgca agaactattc actaatcagt ttataaaata ggagtgatag
    12121 atatgtcaat ccaaatcagc cacttgaatg tagtcattga aaacctgaaa atattagaag
    12181 acatccattt cactatccct aaagatacct ttacatcgat tgtcgcgcca agcggagccg
    12241 gtaagtcaac attgctgaaa actttaacag gagtccagcc tatgacttct ggaacgatca
    12301 aagtagacga tcaaaaagta actggtctcc atacagcatt tagttatatg ccgcaagaag
    12361 atatgttact tccttggctg agcgtctatc aaaacgttac gttatatcaa aaaatcaatc
    12421 atctaacaat caatgaagaa caagtaaggg attatctgga tatctttggg ttaaacggct
    12481 atgaacattt tttgccggaa caattatctg gcgggatgaa gcagcgaacg gccttgttac
    12541 gaacaatcat gaatccttct tcttacttgc ttcttgatga accatttgga gcgttagatg
    12601 ctatgaccag agggcagatg caagactgga tgttgaagct gcctaaaaaa gcaaagcgga
    12661 ctactttact tgtgacgcat gatatcgaag aagcaattta tttatcagac aggattcttg
    12721 tgctttccgc ccgtccggca catgtgattg ctgagattca agtgcctgaa aaacgacggt
    12781 cacgtgaatg gctactgcag caatcagagt tgaagcaaac gatttatcag ttattggcag
    12841 gtgaattaga tgttaagtga tgctcattgt catttagatg ggagtcagag tttagcactc
    12901 cttcagcagg aacacacgat tttgacgatc atcaattgtg attcgccaga agaatggaag
    12961 gaaaacagac agcttgcagc aagtaagact caagccttaa gttacggtat ccatccttgg
    13021 aaagcagata gctatacgtt tgaacaagtt gagccttttt tgaaaaaagc aaggatcatc
    13081 ggtgaaatag ggttagataa tatttggacg aatgtaccga tgactacaca aaaaaaagta
    13141 tttgagcgac agcttgcttt tgcagccata aatgagaaac ctgttgtact gcacacaaaa
    13201 ggatgcgaaa aagagatctt aaattatatc caagcttacc ctaatcacta tttgatccat
    13261 tggtattctt ctttggacta tcaacaagac tatattgatt taggctgtta tttcagcatt
    13321 ggtcttgatt tgaaaaagaa tccagcagtc tggcaactag ctaaagcagt cccaatcgac
    13381 cacttactta ttgaaacgga tggactacat gcagcagagt gggctttagg ggggattttt
    13441 tcagaaaaag attatgtctc actgcttgaa gaacagttaa agacaatcgc tgagatcaaa
    13501 gagctatcag ttgaagaagt taaaaaaaat acttatcaaa acttggaacg tttcattaga
    13561 ttaggtaaat aaaaaagaga tgtgacacaa ctagtgtcgc acctcttttt ggctttcttt
    13621 gtataaaagt aaactgtttg attaataaat gaatcttagt accaaccgtt tgcttcccag
    13681 aatgctttcg ccgcttccca agaaccataa cgtgaagtaa catattgttc tgctactctt
    13741 tcttggtttg cagcagagta gtcaccattt aagtaagaag aatctaattg gtaacgtccg
    13801 atgtaacgtc cgttcgttgc tgtgtaagaa ccgcttgatt ctttttgtgc gatccattct
    13861 tttgcagagc ttgtgcttgc tggagtagca gcagtttctg ttacagcagg agcaggttgt
    13921 gtttcagcaa caggcgctgc ttgtttttcc gtttgaaccg tttcttgtac aacaggttgt
    13981 tcagcttgga ctggtgcttc ttgaacggct gcttgaggtt cagcagctgc ttgtgcagag
    14041 ccttctgttg ggattgttaa ttgttgtcct gagtaaatca ggttaatatc agaaattgaa
    14101 tttgattctg caatggcatt gatcaaggag ttatcaccaa cgtatttttg agaaatcgtt
    14161 gatagagtat cacctgattg aacggtataa gcttcgtccg catgagcagt cgttcccatg
    14221 aagaatgcag cgccggcagc caaagttgtt ccaaaaagta aagttttaag tgatgtcatg
    14281 aaaaatctcc tttattcgtt aaaaagtttt atttgttgtg ttcaacgagg aatactttaa
    14341 cacgtgaaaa tatttcatag gtaaaagaag catgacaatt tatgacaaat ccgcgttttt
    14401 tgtaataaat acagtaatct atgaaatgaa aagggttacg tttaataaaa cttgcttttt
    14461 tgtttttgtt caccataaat atttatttaa gaaagtatta acctgcattt ttctctataa
    14521 aaaagatttt ttaaatagat aaaaaaggag gattaaatga gtatttgata gtatttatat
    14581 taaaattaca tatgtaattt aaaaacgctt gacattgtgt ttgagatcac ttacttttag
    14641 catgtaaaag tattggatta aggagctatg caaatgaaaa agaaatttat tactggtggg
    14701 attgtcgttg catttctatg tctaattggc tacacaggca cgcggtacgc aaatgaaatt
    14761 attttgtggg gtggagagac agatattgat acaatcaatg agaatctgac acagcttgat
    14821 catacattga cagataaaga gcaagcgatt acagatctta ccgctcgact agcacaaaaa
    14881 gaacagacat tgcaagattc aaaggcagat gtccaagaat accaaacaaa agtaaatgaa
    14941 ttagaaaacc aaaaaaatca atcggcagca gaaaaacaaa acttagaaag tcaattagtc
    15001 agcaaggatg cacaactaca aagcaaacaa aatgaaatca atgtcaaact agatgagatc
    15061 aaccaaaaaa atgatgaaat caatcatctg aatgcagatt ggacagcaag actacaagaa
    15121 gcacaagcaa aactttcaga attacaaaat actgtaaatg gtttgaatca acaaatcgca
    15181 acactgacac aagaaaaaac aaatgtagaa atcagttaac agatacacaa aagaaattag
    15241 acgaagcaac tgctgaaaac tcaagcttga aacaatatat tcaaaagtta gaaaaagcaa
    15301 aagatgaagt ggaagataca gctgataaat ctcagcaaat tgttgaagaa catttgcgta
    15361 aataatcttt cttaacaagt aaacctaaat tagtaaagaa gcaacagtaa tctatactgc
    15421 tgcctctttt ttttagtaca tgtccttcat cttcgcagga agtgccaata tgattttaag
    15481 aaaggtaata gacaaaaagt caaaaagata aaacagagtt tcttctttac aaagggaatg
    15541 tatgttcgta taatggtatt gaggtgaagg ttatggagaa aaaatatgga acagtagata
    15601 agatccgtac tttgcaagtt agtgccagac cgttgatccg tttcagttta aatggggtca
    15661 attgtttgat tgcttcccat agtttgaact tcctagctga agtagacgaa gggatgaagt
    15721 tagtcgttac aggttattat aataatagaa agcaatttgt tgtgagatcc tatcatgtgt
    15781 tagggaaacc caaaattgtg gtagaatatg agaaaagtct atacccaaga aaaaaggtcc
    15841 gacaagatga aagaataaac tagaaaacaa gcggctgaga caaaaatgtc ctagccgctt
    15901 gttttggaaa gatggatgca gacgatggga tttgaaccca cacgagcata cgctcacaag
    15961 aacctcaatc tatatataac tacatgtatt taagtatttg tgatgaatca ctaaactttc
    16021 caaactcatt tgagggatat tgcttaaaga ttgaacagat caattcgaag ccctattagt
    16081 attcgctcaa tggggggatc agaggccata aaaagagact agtcattact agtctcaggt
    16141 agtggaattg taggatttta aacgttcctg gagagtaccg gtatgtaact cgaagaggtg
    16201 attatcatag tcgtaaaagt aaattgaaga agcctcgcct ttcacacgag aacgtcctgg
    16261 ttcgacagtt aaacctaaca tttggatttt tgagacaaac gaatctatat cttgttcgtc
    16321 aattttaaaa gcaatatgat tgtatgtctt tggcagttta ttcgacgaat tctgcattac
    16381 tgcaatccat aggtccttaa ctaagaaaaa tttttctgga tataatgaaa atttttttgt
    16441 tgactatcgt agatttcttt tgcatcaaat aaggtattta acaattaagt atttaaaaga
    16501 taacttttaa gttatcttta agtaatgctt aaagctatgt tatactctat taggaaatat
    16561 aagaaggagt ataaaaatga acaaacataa tagaaaaata acgaataaca aagaactgat
    16621 cttgttacta atagggattt ggggtatctt tttactcttt aatatgtata tgccgactat
    16681 gagagcggat gacgtagttt atgcaagtag attagatgaa cttggctatt tgggtgcttc
    16741 gatagaacat tataagacat ggagttcaag aattattata gaactattct taatgttctt
    16801 ttctaaacac tttatgctat ggaaattatt aaattctacg attatgttag gaattgtagt
    16861 attactttgc aagtat
//
LOCUS       DAPBBV010000054        15960 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.054, whole genome shotgun sequence.
ACCESSION   DAPBBV010000054 DAPBBV010000000
VERSION     DAPBBV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.054"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..450)
                     /locus_tag="RD486_002345"
     CDS             complement(<1..450)
                     /locus_tag="RD486_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7664060.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITN"
     gene            674..1465
                     /locus_tag="RD486_002346"
     CDS             674..1465
                     /locus_tag="RD486_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7664061.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1431..2384
                     /locus_tag="RD486_002347"
     CDS             1431..2384
                     /locus_tag="RD486_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HDT7664062.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2782..3756)
                     /locus_tag="RD486_002348"
     CDS             complement(2782..3756)
                     /locus_tag="RD486_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7664063.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3871..4305
                     /locus_tag="RD486_002349"
     CDS             3871..4305
                     /locus_tag="RD486_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7664064.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4430..5452)
                     /locus_tag="RD486_002350"
     CDS             complement(4430..5452)
                     /locus_tag="RD486_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HDT7664065.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            5844..6266
                     /gene="arsC"
                     /locus_tag="RD486_002351"
     CDS             5844..6266
                     /gene="arsC"
                     /locus_tag="RD486_002351"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HDT7664066.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETHGLN
                     PRAIKIMAEDGIDISKQTSDLIDRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDL
                     KDPAQAVGSEEEILTEFRKVREGIKRKVLDLNQRTSIV"
     gene            complement(6546..8468)
                     /locus_tag="RD486_002352"
     CDS             complement(6546..8468)
                     /locus_tag="RD486_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDT7664067.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(8555..10495)
                     /locus_tag="RD486_002353"
     CDS             complement(8555..10495)
                     /locus_tag="RD486_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDT7664068.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            complement(10783..11523)
                     /locus_tag="RD486_002354"
     CDS             complement(10783..11523)
                     /locus_tag="RD486_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HDT7664069.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
     gene            complement(11536..12627)
                     /locus_tag="RD486_002355"
     CDS             complement(11536..12627)
                     /locus_tag="RD486_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HDT7664070.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            complement(12617..13723)
                     /locus_tag="RD486_002356"
     CDS             complement(12617..13723)
                     /locus_tag="RD486_002356"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HDT7664071.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            complement(13742..14419)
                     /locus_tag="RD486_002357"
     CDS             complement(13742..14419)
                     /locus_tag="RD486_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HDT7664072.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAMILG
                     AIFPAVN"
     gene            complement(14430..15209)
                     /locus_tag="RD486_002358"
     CDS             complement(14430..15209)
                     /locus_tag="RD486_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HDT7664073.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            complement(15238..15588)
                     /locus_tag="RD486_002359"
     CDS             complement(15238..15588)
                     /locus_tag="RD486_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HDT7664074.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            complement(15604..15960)
                     /locus_tag="RD486_002360"
     CDS             complement(15604..15960)
                     /locus_tag="RD486_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HDT7664075.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
BASE COUNT         4736 a         3344 c         2689 g         5191 t
ORIGIN      
        1 atttgtaata agttcgtata tgttttgcgg tgtttcttgt ttcttgtaat tttccacgaa
       61 tgtttcatcc atgaataaat tcataaacgc ttgaagtaat cctacttgtt cttttggttc
      121 tttgattcct aaaaaaaata gattttctac agtcatttcc tgattatccc ccatttgata
      181 aaaataaatt gggttcttca gctgcataac aaaaacaaat ggcttttcga catattcaca
      241 ttccgaatgt ggcagcgcga tatttaaata cttagtaatc aatccagtag gaaattctct
      301 ttctcttgca atcagtccat tcaaataatt ctcattgacg taccccattt tttctaattg
      361 ttgtgcagcg attaaaaaag cttcttcttt attttttact tctaccgcta attgaatcaa
      421 actaggaacg aacatctctt tatatttcat tccaacctcc tcctttttga ttaagtttgt
      481 taatttattg ttctactaag ttcatctttg ttttacaaga acattatatt tctgttagtt
      541 tgttttgtca acgctttcaa aagaaattta ttttgttaaa tttgatctac ttgaaaataa
      601 aatcgtttat ctatataatt aagaagaaca aagtcgaaca aaaattgact tttatgttaa
      661 aggagtaatt catatgctga aaaaagaaag acaagaacaa atcattacat tattagagaa
      721 agatttttat ttaactaatt cagaaatcgc taacaaatta ggcgtatcag aaatgaccat
      781 acgccgagat gtcactgaat tagcaaaaaa aaataaagta aaaaagctat atggtggcgt
      841 tgaacgaaag gaaccttata atcgagaact atcgactcaa gaaaagattg atacgaatgt
      901 agccgaaaaa aaatatattg gtcaagtcat gaacagtatg attcccgata attctactat
      961 ttatgtcggt gctggaacaa cgatcctata tgcacttcct ttcattcaaa agaaaaatct
     1021 atttgtaatt acaaacagtt tgattgcttt caactattta aagaatcata caagttatcg
     1081 gattttactt actggtggcg aattttctcc tattacagaa gagttcattg gggaagttgc
     1141 agaaagatct tttgaaagtt tgaatgtcga tatctctttc gctgcaacaa acggcatatt
     1201 tgataacaat gtgacaaccg ctcaatttat tgagggaaat attcagaacg cagcgctcaa
     1261 tgcagcaaaa atcaaatgca ttgttgcaga ttattcaaaa ttaaataaat cagacgtcta
     1321 tacttttaga aaattaaccg attttgatta tctaataacc gataatcatt tatcagaaca
     1381 ggatttcaat cattattcaa aatacttaac aatattaaag gagcccaaaa atgatactga
     1441 caatcacgat gaacccatcc attgattcca tttattttac aaaacacttt gaattaggta
     1501 cgatgacacg ctttgattct ccggtacgct atgtaggcgg caagggaatc aattgcggac
     1561 gagcttctgc tctactaggt tcatcagtta ttttaacagg gtttttgggc ggttattttg
     1621 gcagtatgat tcaagatatg ctgaaaaatg aaaatttgtt tgatttgcat tttttaccta
     1681 ttgcagaaga atcaagaggt gccgtcacga tcatgcatga tgatgaaacg cagacagagc
     1741 tagtggaagc tggtcctgaa atagcagata ctactatcaa aaaattaatg aatgatatca
     1801 aactaatcag taaaaataat tacctttcag tcattacaat aaatggttct gttaacaatc
     1861 cagatccctt tttgtatgct aaattattac aatatatcaa agaacaaata gatccttcca
     1921 cctatatatt aatggatata tctggacaac atctccgtga agtcttagca agtaagtata
     1981 aaccgatgtt catcaaacct aatatccatg agttttcaga tatcatccat caaaaaatta
     2041 ctcaaaaaag cgacataaaa caccatctaa aaacaaatcc actatttaaa gatatcgatg
     2101 ttatcatgat ttcttgcggc tcgtatggtg cagtagtcaa agtaaaagaa gaattttgga
     2161 atgttgagat ccctaagatt cctatcatta atacaacagg ctctggggat gccactgttg
     2221 gaggttttgc tcattcatta gaacagaatt atcctttaaa agaatgtgta aggtacgcaa
     2281 tggcttgcgg catgtcgaat gcacagcaat cagaagtcgg gaaagttatt ccagctgatg
     2341 taaaaaattt agcaaaaagc attaaaatca cagaaatgaa ataaatagta caaagtaaat
     2401 aattgtttat atgaaatgag acacaaagag actgtgacaa aaaacgtgtg taccgacccc
     2461 caaaagttag attttttggt ctaacttttg ggagtcgata cattgtcaca gtcctttttt
     2521 cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
     2581 gagaagctat tttttgaaat tgctccttgt gactcagagt taaacggcag gctcacgacc
     2641 tcttggtata aacggtgttc aaaagcttgc atctacgcta atgagtccaa ccaagtcaaa
     2701 aatgaggagc ttttttggct gtccttatta cttgatgcag ggcagttttt tcataatctc
     2761 ttttagatta aatccttttg gttacacaag gttctcttca aagaatgttg ccattttttc
     2821 aaatggaatg atgtctgtct ggtcgtatag atctgtatgg gatgctcctg gaatgatcat
     2881 gagttccttg ttgtcacctt ttagttcttt gaaagcgtcc tccccaaagt aacgtgaatg
     2941 agctttttcc ccgtgaatga ctaagactgc atgacggatt tctggaatat aatgcaatag
     3001 ttttgcattc ataagtgaca accctgatgt cctattccaa ccatcattgg agtttaaaga
     3061 acggacatga tatccgcggt ctgttttata atacgcatga tagtctttga caaattgagg
     3121 agcatcttca ggcaacggat caaccacacc tccagcacgt gcgtagtccc cttgtttgaa
     3181 atcaatgatg cgttgtgcat ttaattcttc acgcatttca tatcgggcat tttcatccat
     3241 aacatcgaag tagccatttg ctgttactcg agtcatgtca tacattgtgg aaacaactgt
     3301 tgctttgacc cgcgtatcga tagctgctgc attcaatgcc atacctcccc atccacaaat
     3361 accaatgatt ccgattctct cagggtttac atttttttgt acagataaaa agtctactgc
     3421 cgcttggaaa tcttccgtat tgatatcagg cgaagcaaca tatcgaggta ctcctccgct
     3481 ttctcctgta aacgatggat caaacgcaat cgttaaaaag cctctttcag ccatcgtctg
     3541 cgcatataga ccagacgatt gttccttcac tgcaccaaat ggcccgctca cagcgattgc
     3601 cggcaatttc ttttcactta cttcttttgg ttcatataaa tcagcgacta atgtgatacc
     3661 aaaacgattc gggaagctca cctttcgatg attgacttga ttgctttttg gaaatacttt
     3721 gtcccattct tgtgtgatgt ttaattcttt attcatattc tagactctcc tttgatcaaa
     3781 attgacattt gtttttgaat gtattattat gataaaactt aaacttgact ttaggtcaag
     3841 gtaaaaattt tattttagga ggattttttt atgtattcca ttggacaagt gtctgaaatg
     3901 tttggattgc ctgtttctac tttacgttat tacgacaaag agggattatt tcctgatatc
     3961 cagcgtgttt ctggtattag aaaattttca gagaatgagt tagaggcttt aagagtcatt
     4021 gactgtttga aaaaatctgg tttagaaata aaagacatta agcaattcat ggaatggagc
     4081 aaagaaggca gtaagacatt tgaggttcgt aaagaactat ttgaaaaaca aaaagaagta
     4141 gtagaaaaag aaatagcaaa attagaaaga gtactcgcta tgctaaacta caaaagctgg
     4201 tactatgaag aagcaataaa agccggcaat gaagaagccg tattgacaat gattcctgat
     4261 gatttacccc aacatgtaaa agaagcttat gtacattctc attgaacaaa cggataactc
     4321 actctccttc tctatgaact tcatgaaaac atgaataaac acctctaact gattgttaga
     4381 agtgtttatt ttttcactca agtatcctgc acttacaaaa atatcctttt taccgccatc
     4441 ctaattctgg agcgatatct tttacgattg tttcaagcaa gtgcatgtta tattctaccc
     4501 ccaaagtatt aggaatcgtg acaagtactg tgtctgcttc tttgattgct tcatcttcag
     4561 ctagctcctt gattaattga tcaggttcac cagcaaaagt ttttccaaaa atcgttgggt
     4621 ttcggtgata agcaagatag ccgacagcat cttgttgcgg actaccgtct tgtccaaata
     4681 agcgtcgatc caaatcagtg gtgattggct gaatcgagcg agtaactaat gttcttggtt
     4741 caaaatcatg acctgcttgc ttccacgctt ctttatacgc acgtaattgg tttgcttgtt
     4801 ggatatggaa tggctcgtgg gattcgtaat tgactaatgt agatgattgc agattcattc
     4861 catgttgtgc tgcccagatt gccgtttgct gcgaaccagc tccccaccag attctttgtc
     4921 gtaatccttc tgaataaggt tctatccgta attttcctga tccttgtggg aacattggtt
     4981 gaggatttgg ttcttcaaat ggttttcctt caagtaattc caagaattca agggtgcgtt
     5041 cccgtgttac ctctttgatt tcttcttcac tgtaatcata accaaagtat ttccagccat
     5101 ctagaacttg ttcaggtgaa ccacgcccca ctcctagttg cactcttcct tgcgtgatga
     5161 tatctgtcaa tccggcattt tctgccatat aataagggtt ttcatatcgc atatcaataa
     5221 gtcctgtacc gatttcaatc ttacttgtct ttgcgccgat tgccgctagc aaaggaaacg
     5281 gcgacccaat ctgaggggca aaatgatgta cgcggaaaaa cgctccgtcc actccgattt
     5341 tttctgcttc caccgctaaa tcaatcgatt gcaaataagc atcttgagct gatttcacaa
     5401 gcgatccttg ctccatccaa tgtccaaagc ttaaaaagcc gatttttttc aaggtaatga
     5461 cctcctttaa acctacaaaa atggaaggtt ttttattttt aatatgaact gattctacta
     5521 ctttttttct taaaagacga ataattgttc tcgcctcaca atcaagaaat gtatcggctt
     5581 actacacccc tactttcttc atcatctgcc gtgtcttaat ctcttttaac agtctgttac
     5641 atcgttgatt tttgactcaa aatgattgtt tctaacatgt atttatggta aaaaagacaa
     5701 gattagttct ttgtacacat cgatttatac gctgaacaaa aagaaatata taaactaaga
     5761 aacccattgt tttttcgctc catcacatag agtttacttt agataaacag tgacatttac
     5821 taatccataa cggaggaaat caaatgaaaa aaatctattt cttatgtacg ggcaattcat
     5881 gccgcagtca aatagcagaa ggctacgcgc gtaaatactt gtctccttca atgtttgaga
     5941 taagaagtgc ggggatcgag acacatggct tgaatccaag agctataaaa atcatggcag
     6001 aagacggcat cgatatttcc aaacagacgt ctgatttgat tgatagagat tactttactc
     6061 aggcagactt gatcattaca ctttgtggtg atgccaaaga caagtgccct gccgttccaa
     6121 acaatcacga acaccttcac tgggacctaa aagatcctgc acaagctgtc gggagcgaag
     6181 aagaaatatt aacggaattc agaaaagtca gagaaggaat caaaagaaaa gttttagact
     6241 taaatcaacg tacatcgatc gtataaagaa gtattcaaaa tgatttttca agcactaaga
     6301 aacaatgtta aaaaaatagc tttccatatt ttacaaaatt gtgccttatt gccgacaaat
     6361 tgtctcttga acaccgttta ccagtagtca agacatcgta agcaactata aaaaattata
     6421 agaaactcaa aataaaagga tgtgccacaa ctttggccac atcctctttt tttgtattta
     6481 gttttctact tccaaataaa tagatagaat tattataaat ataaaggcag ttttttaatc
     6541 gctacttatt cataactaga taacaacgtt aagatttcta gcggatgatt ggattgcatc
     6601 aactgagcca tttgttctgg ctgcttttct agatagtgaa taacagaaaa tatttttttg
     6661 aactctgcat gtttcaaatc atttttcttt attgctaata gcagtacgat acgtatctgt
     6721 tccccgtgcc ataggactgg ttctttcatt gtagcaatag aaatcatcga atgcttcaca
     6781 tacagcggat taccgtgagg gattgttaca aatggtgcta ctctagtact ggagtgactg
     6841 tctctttcca agacagaatc gatgaattcc ggctccacat aatgatgttc cactaagacg
     6901 tttcccataa agtttaaaat atcggctggg tctgtccgtt caagttgagg aaagatcaga
     6961 aatggatgag taaagcttgc tagatcaaat gtttttttct tcttgatagg cacatgctcc
     7021 agcatatatt ttgtcaaata ggctagatca gtttctgtga tcattggtga gatctcgatt
     7081 actggaatgc ttatatgttt aaatggtaac gtagccaaga taaaatcaac agagggaaaa
     7141 tcttgtctct ttaattctgg cttatattca actagatcca taatcgttaa ttctggaagt
     7201 tctctgttca gccgtgcttc gagaaaagta gccatagctt ttgaatattc actaactaaa
     7261 accgtttgat atcttctact tttctgatgt ttgtgtcgct cgatcgctgc ttggaaatgg
     7321 atcgttaaat aagctgtctc ctcttgtgga acataaaaat tttccttttc aaaataatct
     7381 tctaaaatta actgtaaaac taagaaaagt tgtgtgtacg tactaaacac atttttcgtc
     7441 aatggattag aaatctgcaa accataatgg agtcgaaaat aagttgaaga taaatgagac
     7501 cttaaatttt gttttagtag ctgatcttct tttaatgaat agcctagaaa ctgttccact
     7561 tgttcgatca aatgatcagc aagtgcgcta gattcctttt gaaaacgtgt ggctgcttgt
     7621 gaatttgtaa aaagattggc gatacgcaaa gccagataat tgatttcatc aggagaaaat
     7681 tcaattggat agatggtggc tagttttgct aatatttgac tacttaactt ttgtgcttgg
     7741 gtgtgttcca cgacttcgtt ttcgtcttta cttaatttca ctttctggta ctgtttcatt
     7801 cgctcgagca taaagtagat gtgaatctcc acactagcca gtccattcgg ctgttctaaa
     7861 tggttttcat aaaaaacatc ttgtaatgta tgttggataa cttttaatgt atctttagcg
     7921 aagaattctt tcaacgacgg actttgtgga tcttctttct gcatatttcg taatgtctta
     7981 acaagcaact gtcttttttc ttgttcatcg cctttaagaa aagttcctag ttttgttttg
     8041 gatactagct gtaaatggtg atactcaaaa aagctttgca actctgtcaa ttctttacga
     8101 atcgtacgtt ttccaacata tagtttttct gaaagttctt caagactaaa tccgtctttt
     8161 gctactagca gatggaaaat caataactga cgaagctgtt ttttatccat ttctgtttga
     8221 gtctcttcat taagcgctcg tttcagttgt tccctttcgt gaggcagacc attcaacaag
     8281 atacctgtac ctttttttct ttcaaacatt aaaggcagat gtttgtctct caaccaagtt
     8341 tcaatggtat tcaaatcgct atgaatcgtt ctttctgaca catggaaatg ctctgctagc
     8401 ttttttgttg ttatataatt attgttctca cttaattgat agatcaaaga ttgctgacgc
     8461 tgattcataa tgtgcagaaa ctcccttcta aataaaaaat cgatcatgat aacacatcta
     8521 ttatgtctca tcacggtcga tttttcatct tatgttacat ttcgcttaat aattggtgaa
     8581 ctgttgtttt atctggcgct tccatcagtg cttgacggaa gtcatcatcc atcaatttac
     8641 gtgatagacg ttgcagtatt ttcaagtgca tatcaccttg gctgttttca ggtacagcaa
     8701 tcataaagat catatgtgca ggttttccat ctaaagaatg ccaatctacc ccagattgac
     8761 ttctggcaaa tgccactgtt ggtttaagaa cataagctga ttttccatgt ggaatagcaa
     8821 tccccatacc gattcccgtt gtactttcat gttctctatc atagatgact tctttaaatc
     8881 tggttttatc tgtgatcgcc gctgtttttt ctaaacgttg gactaaatct tcgattactc
     8941 cgtcttttgt tgttgctgtt tcacctaaaa cgattgcttc atctgacata atatccgtga
     9001 tagaatcaaa agtttcagtt ttcgtataaa catcacttgt ttcagtctct gatagatctg
     9061 ctactgtcac accatttgct gcagcaaccg cagtttgttg taatgtcggt ttaaggattc
     9121 ttaacattag cacggttaca gcaataccag caatcactgc tacaaaaaac atggctacgt
     9181 gatccactgc tcctaaaacc gctacgatcg gaccgccatg agctacatga tctgtcactc
     9241 ctgaaagcat cgcgatcaca cttcctgtca ttgccccgat tacaatgctt ggaatcaccc
     9301 gtagtggatc tgttgaagca aacggaatag cgccttctgt aatcccaaac agtcccattg
     9361 ctaaggacgc cttaccagct tctcgttctg ttttcgtaaa tttggttttt aaaatcaatg
     9421 atgccagccc caatgctaat ggagggatac agatagctac agcaattggc cccataatgg
     9481 aataattgcc ttctgcaatc aagccagatc cgaacaaaaa ggctacttta ttgaacggcc
     9541 cccccatatc aaaagcaatc atcgctccta agatcatagc tagaacaatt tcacttcctc
     9601 cttgcatccc tgctaaaaag tgagtcaatg aactaaatag aagagctact ggttctccaa
     9661 taacatagat aaacacaaaa ccaactgcca atgatcctaa aattgggata acaataattg
     9721 gcatgatcga ttgtaaagct ttcggtactc gcactttctt gattcctaaa gcaatgaatc
     9781 ctgctaaaaa tccagtgatg atcccgccta agaatcccgc attcgcatca ctaccatata
     9841 atgctccgtt tgccgctaac atcccaccaa caaatccagg aacaagtcct ggacgatctg
     9901 caatactttg cgcaataaat gcagatagaa ttggaaccat caaccccata gcgatacttc
     9961 cgatactatt catcgttgcc caaatcgttc cttctggtat cttgatccct tcaggtgtag
    10021 ctgttcctcc taatgttaaa gaaatcgcga tcaataaccc tcctgtaact acgaaaggta
    10081 ccatgtacga aacgccattc atcaaactct tatagatttt tttacctaaa ttttctgatt
    10141 cacttttatt ttcggaagaa ataattgcct ccgtactttt atagactggc gcttttcctg
    10201 ctaaaatatc tctcaccaac tcatctgcat ggtggattcc ttcttgcaca cctacggtta
    10261 tcaaaggttt accgccgaat cgtgatttat ctattttagt atctgctgcg atgattacac
    10321 cagctgcttc ttcgatatct cttgcagtca attcattttc aataccgatg gaaccatgtg
    10381 tttcgacttt tacctcggcg ccaactgctt tccccgcttt ctctaagttt tctgctgcca
    10441 tgtatgtatg ggcaatacca actggacagg atgtgattgc aataattttt ttcattttcc
    10501 taccgccttt ctacatttat agtatataaa aacggtttct ttttattaag cacaaaatga
    10561 ttccgtaata actgaaattc ttggaataaa tagaaatttc gctaaaaaaa ttgatatacg
    10621 atttattatg ttgaataaaa taatattgga aaatcttaca tttctgtact tctgcttacg
    10681 tacatctaaa ttattatcta cattaacaat ttccgtaatt aattataaaa agcttattcc
    10741 atttaatttc attctggaat aagcttctta ttttctaatg agttagtgaa taattttttt
    10801 taccatgctt aatagtatct ttacgtctcc tatacgcgta tctcctgttt ctttatctat
    10861 aattgaacta taaacatgag gaatcacttt ttttacacct gcatcgattg caattttcag
    10921 aatttcttca aagtttgaaa gatcaattcc tcctgttggc tctaaataga attcatattt
    10981 tgcgcaagct tccgcaactg ctttaaattc ttccctatgt gctaagcctt tcatcgggaa
    11041 atacttgatt gaagtacctc ccatgtcttg cagcatttga atggcagttt caataggcac
    11101 ttcagctgct ggcgcttgtg aacttaacgg acctgtagca atattgacat agccgatctt
    11161 acctgttggt gaaaccaatc cattgatgac tgtatcattt tggcccaata aagcacgaga
    11221 agtccccacg ccagtaaata cttgattgac atgttgtggt tgtaaaaccc cagataaacg
    11281 cgaaaccatc tgactttggt ttggatctcc agcgcctaat ccaactgaca acgcattatt
    11341 ggttgcgtct tggtaccttt tcatatcttc gattgctgct tcatcgctag cataattttt
    11401 cgatagcaca cctagtacga catgcccttc cgctgcttca tagcatgctt ttgcattttc
    11461 aactgaatga gctaatacat ttaaacatac acgattttta taataatttg ggataactga
    11521 caatttaaaa gcctcctaca tgatttctct caatcttttt ataatttttt ccatttcgtt
    11581 ttggctgacg gaacgaatgt cgaactcaat gattccgtta tttgcttgat attctcgggt
    11641 gtagactgct ggatttcgtg cttttaattc ctgaatgact tctttcgcac ttttatcgcc
    11701 attaatcgtt acacttgctc gataaatatc tctgccggca ccatcttgaa ctattttcgc
    11761 tgaaaggtca ggaagttgat tgattgcgtt aacaaaaggc gctaatcgtt gcttcatgga
    11821 gtcaccggat tcgctcccat tttttaaata atcttctagt gcctgggtaa agcctaaaat
    11881 attatcttta ccgattttca ttgctcggcc aataccttta gactgtagcc gaatccattg
    11941 aatatacttc ttttttccta tgaccagtcc ggcactcgga ccttcgattg cttttgcccc
    12001 agagtaaatc actaagtcaa cgcccatttc gctatatttg aataaatctt cttccgcagc
    12061 tgcatcaacg atcaatggca aacgatgagc tttggcaact tctaccattt ctgccaccgt
    12121 cagcatactt ttctgaactg catgatgact tttaatatat agaagcgcag cagttttttc
    12181 cgtaatcatc atggaaacat gttccggtgt acacatattt gcatagccag cttctatgac
    12241 ttttcctcca ccttgagcaa ccattacttc aaccggtgtc ccataatcta cattatgtcc
    12301 cttaggtatg atgatttccc gtctagcgat tttttctgta tagggatgat agacatggta
    12361 catgtcgccc tgtccgatta aagcagcaac agattgagca atccctgctg aagcagaaga
    12421 aacgatttgc gcatcttcca ctttcagtaa ttgagaaaga taagcgccgg ttttgatggc
    12481 aagatcactc atctcaaaaa aatgctcgcc tccaaatcgt tgtgctgcta ggacactttc
    12541 agatacctta gaaaccccta ggatcgtcat ttttcccgat gcattaatga cttcttttaa
    12601 atcaaacttt ccatagctaa ttgtcatata tgacgcctcc aataattgtt ttaatcggta
    12661 aaatttgttc tttagctata cgtgtaaatc cgttggaatc tttcaattcc ttttcatttt
    12721 caacaatctc aaatatcgtc aaatctgcat cataattgac agctaactgg cccttattct
    12781 tcaaatgaaa attccgtgca ggaactgctg taactttttc aatgatttct tcccaagaat
    12841 agccgactac cctcaatttt tctaaagtag ttgctagatc aaaaactggg ccatttgtac
    12901 gattgcggat gtagatatcc gtactaatag aggtagcttt cattcctgct tttagtgcgg
    12961 tttctgccac atggaaatta aagctatccg tcccatgtcc aatatcaaag acgacaccat
    13021 tattgtaagc atcccagaca aagtttttaa tttgatctgt ctttggatct aaaataccgt
    13081 ttggttttcc attaaaacaa tgggtcaata catcgcctct ttccattctt gacaatactt
    13141 cttctaactc aggaggtgca gaaccgatat gaaccatcaa tggcagatca ttgttttctg
    13201 tctggatttt tttagctaat tctaatggct taatgccatt ttcaccaaca actgtcttac
    13261 tcattctcgc tttaatcccg acaataaatt ccggcagttc tgctaacgca gtacttacta
    13321 gatcttcttg aatctttgtt agatcagcaa gttcatcttg tttgacaatg ccccatttag
    13381 agatattcat tagcgcatac acatttgtct tgaccgattt cgtcaattga taaaattcac
    13441 ggatgttttc tgctcccgta gttccagcat caatgaccgt cgtcacacct ttttcgaccc
    13501 ctatctgatc aggatagtca taataaagat tcatcttttc atagcagtgg acatgatcat
    13561 cgatccaccc agcggataaa taatactttc cctccaagtc aactacttct tgcgccggct
    13621 gatttatttc tgctgcaact gctttaatca tgcctttttc tatagcgacc tctattttag
    13681 atccatcaac taaccttcca tttttaatca aagtatcaaa catttaatga ccctctttct
    13741 attaatttac tgccgggaag attgctccta aaatcattgc tcctaaaata gcacctccag
    13801 caattggttt tttccaagca tagaatccta gtgctcctaa tgtagcgcca atgccgattg
    13861 gaatagatgc tgcacacgcg cttaatataa ttaatggacc caaaaaacgt ccagatgaat
    13921 ttcctgcccc catcatgacg tcagcaccaa aagtggaatt tgattgattg atcgtaaatt
    13981 tacgaatcaa gacaatgatg ccaccaacaa tcaaacctag aaccaaacca gtcaataaag
    14041 agagtgcaaa attatcgatt ggtgccgcta ttttcatact taagagaatt gctggtaccc
    14101 caattccgat cccagttagg atcgaaccgc ctaagtccaa gatcccaact aaagagcctt
    14161 ctaaaattct ggcaaataag aaactagcac caaacgctgc cgctgcgcca taggatccgc
    14221 catccagccc ggcttttaac atcgccacga tcgaaacttc attgaatgca cccacaccat
    14281 acatcacata catgtgtgtt cctgcaaata cagcagcgga cataattcct acgattagcg
    14341 gaaaagacca gtctgcaaac caaaagctct tttgccgctt tgcttctaat acttttgctt
    14401 gttcttctgt tgtctccatg attctcctcc tatttcacac taaagatgtt gtgcaagtta
    14461 tcaagccaat taggcacttg aagctggaag ctcttgatca tttccatatc aaatccacgg
    14521 aaaaatccac tgaaaataaa taataaaaca atagcgatca tcatgctctt cgtgacgcga
    14581 ttccaaccgc tctcatcgac gcctttacca atcaagattc ctagaacaac accaggtacc
    14641 gcatttccca taatcaattg cgcgatacca ccaaaaagag tgccccaaaa accagttcgt
    14701 ttccctgcgt ctaaagctgc caaccaaaaa ataactggca ttactgtatt gatcagaatc
    14761 gtcgctgctg gtaccaaaac ggaaaccgcc gtcacttgta acgcctctgg aattgctgca
    14821 gctgttgtgt ttaagaaggc taccaccact gccccgataa ccgctccaat gatccccatt
    14881 tttttcggat catgcatggt ctgggtgaca tctttgtttt ttgctagaag tgctgccgct
    14941 gcccaattgg gaatgattcg atgcgtcaca tcttgtgtga atgcaccagc accaactgaa
    15001 gaagcccatg cattaaagaa aaagcctaaa ccaaatgaaa aatgagaagc tggatcaccc
    15061 atgcaggcat tcatttcgcc taatgttcta aaagctccta aaccttgtgt attaggtgca
    15121 tgaaacattc gagctgcccc gacagatgct gcaaaaccaa gtaatccccc gataatgacc
    15181 gatttgacta gaatgattac gaaatccacg ttattctttc ccccttatga ttcaaaatta
    15241 gattttttta gttacaaatg gaatggcaat cccatttgga tcttcagtca tttgctggct
    15301 gaacgatatg tctgccaatt ttatttctgt tacagccaca gtaacagaga gttcgacttc
    15361 atagctaata cgttgccgtg ggaagaagaa aaatagaaag cgttctgtgt atttgttttc
    15421 gaccgccttt aaaatatcca cattgactgg ttcgattcgc aataatacgt ttgattgttc
    15481 cattattttg ttttgaattt ctgctaacgc tgatgcaaaa gcatgttgct ttgtttcccc
    15541 tttaccggag acgataactt tttgctgaat tgtcttttga acgctcattt catgtccctc
    15601 tttctatttt ccatgctttt tgataaattc ttctgtcaga cgtttcccta attcctcttg
    15661 atccataaag ccgaaaccta gaacagtttt gccatccttg atagctgtga tcccttcttc
    15721 aatcgaacgc ataccatgtc gttctggata gccatatttt gttgctgctg ttaatgcacc
    15781 tgcaccacca ctaccacaaa aagagatacc catatctgca tgctcttgtt gcatcacatc
    15841 gcccaaacgc atatctgccc ccattcctgg tacgacaact gcttttccac cagctgcttc
    15901 tacccctttg gccacatttt gtcctttacc catacggtct gcaataacta ctttaatcat
//
LOCUS       DAPBBV010000055        15932 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.055, whole genome shotgun sequence.
ACCESSION   DAPBBV010000055 DAPBBV010000000
VERSION     DAPBBV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.055"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(481..858)
                     /locus_tag="RD486_002361"
     CDS             complement(481..858)
                     /locus_tag="RD486_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664076.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(1158..2039)
                     /gene="galU"
                     /locus_tag="RD486_002362"
     CDS             complement(1158..2039)
                     /gene="galU"
                     /locus_tag="RD486_002362"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDT7664077.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(2082..3101)
                     /locus_tag="RD486_002363"
     CDS             complement(2082..3101)
                     /locus_tag="RD486_002363"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDT7664078.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(3734..4738)
                     /locus_tag="RD486_002364"
     CDS             complement(3734..4738)
                     /locus_tag="RD486_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7664079.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(4751..5800)
                     /locus_tag="RD486_002365"
     CDS             complement(4751..5800)
                     /locus_tag="RD486_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7664080.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(5817..6638)
                     /locus_tag="RD486_002366"
     CDS             complement(5817..6638)
                     /locus_tag="RD486_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7664081.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(6625..7404)
                     /locus_tag="RD486_002367"
     CDS             complement(6625..7404)
                     /locus_tag="RD486_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7664082.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(7421..7891)
                     /locus_tag="RD486_002368"
     CDS             complement(7421..7891)
                     /locus_tag="RD486_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7664083.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(7903..8322)
                     /locus_tag="RD486_002369"
     CDS             complement(7903..8322)
                     /locus_tag="RD486_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDT7664084.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(8403..11180)
                     /locus_tag="RD486_002370"
     CDS             complement(8403..11180)
                     /locus_tag="RD486_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7664085.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            11371..11595
                     /locus_tag="RD486_002371"
     CDS             11371..11595
                     /locus_tag="RD486_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664086.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            12374..14089
                     /locus_tag="RD486_002372"
     CDS             12374..14089
                     /locus_tag="RD486_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7664087.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            14092..15855
                     /locus_tag="RD486_002373"
     CDS             14092..15855
                     /locus_tag="RD486_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7664088.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
BASE COUNT         4673 a         3279 c         2724 g         5256 t
ORIGIN      
        1 cattgaacga atacgcccaa taccttgaca tagcaaataa aacaacgtgc agaccatgga
       61 aaatatctac ataggggtag aattttcacc ctagattagg tacaataaat taggtcgatg
      121 cactgcattg actatggcaa aatgatcggt cagggtgtat gtgtgtgact ggtcattccc
      181 tgattcttag cgccaactaa gggtcaggga gccttttttt attcagctgt ttctatctga
      241 atttattgta agtaatctct tatccaagtg caagcaagaa aatacaaaaa aacattggta
      301 tgatttatat atatataaat aacataaaaa aaggaatggc ttatcccgat acaacaagca
      361 ttcctttaaa aaagattctt ttatataagt gaaaaaagct tttttccacc aattaaataa
      421 atctctcatc tcaatagttt atccattatt ttatcttttt ttgcgtatac ctactaaata
      481 ttaccgtctt cttctcgttc ttctactttg ttcgagagaa tctgtactag aaaaagtagt
      541 tgtatgtcta ccttttctgc ctatccgaga ctttcttttc atatatggga tataaatgat
      601 tagatacagt acagcaaaaa ataaagcaaa tacgcaagct tcccaactac ctaacgccaa
      661 ttcaaccatc aaggtagcaa ccccaacgga tgctgcatac cagataaaaa tcagaaacgt
      721 ttcttttttt ctgaccatgc gaaacatgat aaatagacta ataagcaata gtggcaacac
      781 aaatatccaa ttgcttcctt ccatcagcca cttgagtata tcaagcagcg actgtgcaac
      841 agcgactaat tttcccatag tgaacacaca ccttttttta taattaaaaa attcgccttt
      901 ttattctact atgaatcttc tggcttggct ttcatttctc ttatgtaatc attttctttt
      961 atacaactta aaaaaaaatt aaaccattag cataatattt tctgaatcta ttcacgaaag
     1021 tctttttcta tctttcgttt tccacgactc aactgatcta gagtcaaaaa actaaaacga
     1081 cagttgcgca aatgacgcac aagctgccgc tttaataaca aatagccttt cattctcagc
     1141 aggccactta tttccagtta actttctgtt cttagctttt tactcaactg gataatatat
     1201 gcacttaatg aagtcccaat ttccgaatgt tgaagtccat attcaatatt tgtcttcata
     1261 tatcctaact tatcgcctac gtcgtatctt tttcctttaa actctctcgc atagaccgcc
     1321 tctgtctggt taagagtctg aagtgcatcc gttagctgta tctcgtttcc tgctcctggt
     1381 tcttgagttt ctaatatctc aaatatttta ggagtcagta gataacgtcc gataatggct
     1441 aaattacttg gtgcttttcc catttcaggt ttttctacaa acccttttac tctgcaacga
     1501 cccttttcgc tatctgtttt aggatcaata attccgtatt tagatgtttc attttctggt
     1561 acacgcatga cggcaacagc ggaagcttgt gtttcttcat aatccatcat caattgttga
     1621 gtcaatggga tatcatcttt catcaaatca tcccccagca tgacgacaaa cggttcattt
     1681 cctataaatg cttttgcttg aagcacggca tcccccagtc ctcttggatg agattgacgg
     1741 atgaagtgaa gattgacttg agtcgtttct tcaactaaag cgagtaattc tgttttttcc
     1801 ttttcccgca aattgttttc caattcgata tttgcatcaa agtgatcttc aatgggtctt
     1861 ttttcttttc ccgttacgat caagatgtct tcgattcccg aatccaatgc ttcttccaca
     1921 ataaactgga tcgttggttt atccacgatt ggaagcattt cttttgccat ggcttttgtt
     1981 gccggcaaaa aacgtgttcc tagcccagcg gcaggaatga ctgctttttt gaccttcact
     2041 tgctgttcct cctaaacgac gattaactat tgatcatcta tttaacgaag agaaaattca
     2101 ttctccattt ttccgtcacg taacatgatt tcttttgctg cttttttgat atcttctcca
     2161 ttatacaaaa cattatagat tgtttgagta attggcatct caacacctag ctgttgagct
     2221 agctctactg ctgcttttgt cgttgccaca ccctcaacga ccattcccat gttttctaga
     2281 acttcttcca gcttatgtcc ctgtcctaac aagttaccgg cacgccaatt gcgagaatga
     2341 acacttgtac aagtaacgat caagtccccc acaccactca aaccgataaa tgtcagagga
     2401 ttggcaccca tcgcgacacc aagacggctg atttctgcca atcctcgagt catgattgct
     2461 gcttttgcat catctccgaa tcctaatcca tggatagcgc cggcaccaat tgcaatgata
     2521 tttttcagtg ctgcaccagt ttctacgcca atcacatcat tatttgtata aatcctgaaa
     2581 taatcattca tgaacagttt ttgtacatag gctgctgctt tttgatcaat acttgcagct
     2641 gtaattgttg tgatatcatg tactgccact tcctcagcat ggctaggacc agataataca
     2701 acaattgcct gtcttttttc ttctggaatt tcttcagcca aaacttctga gattcgttta
     2761 tgcgtatctt gttctagtcc tttacttgca tgtataatga ttggcttagt attcatttta
     2821 ccaataagtt cctgtgcgac tgaacgaatc gcttttgttg gaacaacaaa taaaatagca
     2881 tctgcgttat ccactgcttc tgccaattct ttatatccga taatcgattc tgggatcgtc
     2941 aaatcaggta aaaaatgctg atttgtatga tacttattga tttcatcaat ctgttcaggt
     3001 acatttcccc aaatacggac atcatgcccg ttttctgcca atgtttgtgc taaagcagtg
     3061 ccccaagatc caggaccaag aactgcgatt ttttgtttca tggatattcc tccaaataaa
     3121 taattgataa tttccattat agtatacatt tcttaaagtt gggactaatt tccattgttt
     3181 ttaagtgttt gtttacttct tttatcgttt ttacttgaaa taatcaatga tatgttacaa
     3241 tagtctacat tttattttta cactcgttat gctttgcttg ttcctaagag gaagcagttt
     3301 tgacaatgtt actaccagca ttactattag gaggttagga aacttctcct agtgagtatt
     3361 gatttaaaat acataagaga cagattgaac atttctaaat ctgtcaggtc ctgcaacgga
     3421 cagattgtct ctgttgacgg ttgacatagg aacttttgtt ttagtcaaca ttctggatac
     3481 aaaacgctat gtaaactggc gcaactcgtt gtacttggac ttttactacg gatccatgca
     3541 acaactaaat agtactattg cataacaaaa aatggttggc acccacatgt cccattaaac
     3601 agattataag ttgaactgta gataatgcaa aaaatgtgtt ttataacgta attgatgcca
     3661 atattttaaa aaaataaagg gagcagttat cgctgctctc tttatttttt atattctttt
     3721 tatccagtct atcctaataa tcaaactgac gatagtagcg gcgtatctct aatggatggc
     3781 agttcaactg ctccacatga gcatcgatgc gttgtgtcac tacatgcatc aataagaaag
     3841 acaaaacacg tccgcgatat ttttcactga taccttctac tggatagtct tttgtgtcta
     3901 tcaatgtata attgctgcaa atttttggca aaagtttagc cacacgttca gataacactc
     3961 tctgttcatc ttcgcctaaa aataatgtga ctggggttgt ttcttctacg atctctaacg
     4021 tcccgtgaag aaactcggca gcatggatag atttcgatgg aagccagctt tgttcttccc
     4081 agtaacacat ggcatatgaa taaacagctc cccattgatt ccctgctcca ataaaataat
     4141 gcatactatc acgtcgatgt ttttctgcaa atgataagcc aaatgcatct gcttttttct
     4201 ctgcttccac taaccctgtt ggtaaataac gttcgagctg ttcatagtat tctgaataag
     4261 cttcgaattc tccattcaaa tacatcaatc gatctgctgc cataaaaaat ttgatttgtt
     4321 ctgttccagg agctggataa gtgaccacaa aatcgcatag ctgagacaac ttactgttcg
     4381 ctttatcgat aaatccaatc agtgtcgctc ctactttctt gatttgttct actgctttca
     4441 ctacttcttg agttgtaccg gtaacagagg acaaaataac gatagaatct tttgttaatc
     4501 ttttgtttcc agtagtgtaa tattctgcag catgctgtac aaagacaggc aagttgcttt
     4561 tcccattcat ataagtgaca gcttgcatcg aggaagcata cgttccaccg attcctagat
     4621 aatagacagc gtcaaatttt tccgcataaa gtttatcgat gatttcttct acttgcggac
     4681 gtaaagctag tgcgcctttt attgctttga tttgttcttc ttcattgaat ttcagcatga
     4741 tttccacctc ttataattta cttttcaaga ctgtatcaaa gtcttcaaaa atctttttgt
     4801 tcaagtcaat acctttagct actgcggttt tataagcgaa tagttgaaac ggaacgacaa
     4861 gcgctaatac agacagatat tcatcacatt ctattgctaa tccaagtgtt ttctcgtttc
     4921 ttgctttttt tgtggtaatg gtgagagtct ctccaacgta ccgactcata tatctttgca
     4981 acttttgcga acgttcctta tttacacttt ccccttcaat aaagaatagc aaatgcgaag
     5041 catctgcctc caggtatggg ccgtgcatat aagcttctaa ctcaaatcct tgtgacggaa
     5101 cgcggattgt ttcagtcaat ttcgtctctg cttctttagc tgttccccag tttggaccat
     5161 atccaatggt gacgaaacgc tgtgctaaac gaaataaact ttgatatcca tcaaaaaatt
     5221 cttccgtttt ttgaataatc gctggtaaat ggttgattat tttgcgcaac tgttgcatgt
     5281 agtcttgttc tatttttttg ctgattttat ttttacttat tccaattcct atccctaaga
     5341 gtagtaactg taaaacagtc gcagaatagc cttttgtaac gaagcctact gattctaccc
     5401 cggcacctaa atcaataatt tgtgcagctt ctaaagcaag tggactttgc acgtcatttg
     5461 tgatagcaac aacaggtaac ccttgttttt gtatcatttt tactgcttca acagtagaag
     5521 cacttttccc gctttgtgac acagcaatca cagtatcgat tgaaggagaa agttttccat
     5581 aattgaaaaa ataaaaaggt tcttgaatat cgacagtaag atcaccataa gattccaatg
     5641 ctggcttcgc tgctaaacaa gcgttataag atgaacccgt tgctaagatc agtaaattca
     5701 ctgttttttt catatgttct cttgtcgaaa aatcattctt tttcaagatc gtacttagta
     5761 cttccttttc ttcatagata taatcttgca tcgtaaacat tttctctgct ccttttttaa
     5821 aaaatcccta tccacgaacc aaaaattcca aagaaagcta gtccgatcaa gatcgttaat
     5881 ggtttcactt ctttcttcaa tagataaaac actatgccaa atgctccaag acataagata
     5941 tttggaacga tatcatcaaa aatactttga acagtcacag cattttctcc tgaaccgatt
     6001 tttaaaggaa tattgatggt gatcatcgtg gcagtcattg ctccaacgac catcagtcca
     6061 ataatagacg cgcctaatgt caaactttcc atcataccgt ttgcctggat ctttttcaaa
     6121 aaacccgttc ctaagcgata tccccaacct gttgctagat agcgaaacag aatgtgcgga
     6181 atattgaaaa tcaaaatgaa caagataggg cctaaaatat ttccttgcat ggctaaagag
     6241 gtacccacac ctgtggcaat caatcgcaaa gttccccaaa agaaagaatc tcctaaccct
     6301 gcaagaggtc ccatcaaaga tgttttgata ctatcgatcg cagtcacatc aaattcagga
     6361 tcatccttat tttcttcctc cattgcagcc gtgattccta aaatcagtgt aacgatatgt
     6421 ggggtcgtgt taaaaaactc tagatgccgt ttcaaagctg ctgccatttc ttctttcgac
     6481 tgatataact ttttcaaaat cggaatcatt gcataaacat aagccatatt catctgacgt
     6541 tcataattcc aagaaaactc catttgaaaa gaacgccaaa atacgtgatt tagctctttt
     6601 ttcgttattt tgctgttttt gatctcagaa ttcttcatct tcttctacct cccctgcagt
     6661 tgtttgaagt ggtagttgac ggacattcat aatattgact accacaactg ctaaaatcgc
     6721 accaaaaata gctactccgg tcacaggaat ctctaagtaa gaagctatag caaaacctaa
     6781 gaaaaaatat ggtgcaactt gtttgttgat cagcaaacga gcaagcatcg caaaaccaag
     6841 agctggaatc aaccctgtag ctactgacaa ccccttttga acgaagtcag gaatcatatt
     6901 taatagattt ccgatcgtat tgcttcccac catataagaa accattacca caacaccaag
     6961 catcaaggaa agaccgatac cggcaagcaa gtgcatatgc tcgactcctt tataatttcc
     7021 ttcttctgca taattgtctg ctttatggtt cataattgga atcaaaagcc ctaagtaaat
     7081 atttttcaat atcaatgtca acgtagcaat cggcaaacct agtaaaagcg cggtttctgt
     7141 accggctcca gctgtaatag caaaagccgt ccctaaaatc ccaccggtca caacatcagg
     7201 tggaatcgaa gcacctactg agaacgatcc gataaatgct aactctaaag ttgcgcccat
     7261 aatgatccca gtttttacat cacctaacac gattcctgta aacagccccg tcacaatcgg
     7321 acgagaaagc aacgatgtcc ctagtgcata ttctgattgt gcgacaaatg caacaattcc
     7381 taataagact gcttgtacaa tcattgaggt tcttcctttc ttacaaaact tctcttacat
     7441 ccactttttt atctgctggt acttgacgga tttctacttc tatttgtttg tcaattaatc
     7501 gtttcaagcg ttcctcctct tctggtaaaa tatttaccgc ttttccgatg ctgcgagtac
     7561 caggttttgc cttgatccct cctaagttga tggttttgat ttctggatac gcttctgcca
     7621 gcttatatgc atcctcgatc gattccacta cgatgaataa cttatattta tctgtcaccc
     7681 cgcttttcaa cgcggcaatc gagtcatcaa ttgatttgat cactagtttg actccttgtg
     7741 gcttggctaa tttgatcgtt gtctttcgta tctcattcgt aggtacatca tcattagcaa
     7801 tcaaaataca gtctgcgcct attgtttgtg tccatgaaaa agctacttgt ccgtgtaata
     7861 accgatggtc gactcttgtc aatacaatca tttttcttcc tcctaaaatt cgtcttcttc
     7921 tattttctga ttgagccgct cgttacaaaa ctggatcatt ttttttgaat cagttagcac
     7981 ctgctggatc aaaacagttg tctctacttc agcgtccaac cgagatacta gctcaatcaa
     8041 tagtggcaaa ttcaatccgg caacgagata gacatgatcc cgattgatat attgtaagaa
     8101 ttcgttgttg acacttccgc caaaaagatc cgtcagaaca atgatttctt tatctttgta
     8161 cctcataaaa agctgcctta ctgtttccgc taaatcaaaa ttctcatcag tatagcaatc
     8221 gaatacagta atagaatgat ttttcccata gatcagctct aatgaatcta atatccctga
     8281 agcaaatttt ccatgggaag ctaagataat ttctctatcc actttttcat ctcctctttt
     8341 cacttacaca tactaaaaaa gcaagttgca tgccaaaatt agtggcaaca acttgcttat
     8401 gttcaaaatt cttcttctat cgagagaaac tctgtatctt cactcaaaat atcatagata
     8461 taggcaatct cagaattggg gatcatgaca ctataatgct cttcaatgac actaaacgca
     8521 gatttaatag cagataaccc ttctttttga cactgcttcc atttctctaa tccttgatag
     8581 gtttcgattg gcatttgtcg gatcaatcgt tcaatgagac agctcacatg gacatacaac
     8641 gctaattttt tgggattgct gatgcttcga ttcaactgca cctctaattc tctcataaaa
     8701 tgatcgattt ctcccatcac cttctctgta tctagaatag tcacggaatc cagtactttt
     8761 tccaatgaaa aattacgaat gatgcgctga ttgaatattt ccttctctga agcattcata
     8821 gtagtgtcca accattcagc tagtacagac atcttttccc ccgagatgag gtcttctaat
     8881 gaaagatagt cgatattggt gatatcagga tctgtggtgc caatcattcc tacgacttcg
     8941 tatatggaaa ataatgggtc actgtttttc ttatctttta attgctgata ttcatatggg
     9001 atgattttca actgacaagc cgtaggtaag cttttttcta gcagttcact taagtggacc
     9061 gccgtaccga ttccagtgaa gcaagtagta atgagtgctt tgggtttgtt ttcctctgga
     9121 tagagcagtc gccattctgg ctggatctgt cgaacagtct cttctgctat ctcttctaat
     9181 gatacatttt tttgcaggca ttcccctact gtgattgcta aaggtgtcgt cacattattc
     9241 aaaatcaaaa gcggtacgga taactgtttt ttaaaaaact gatggatttc tttcagagat
     9301 cccatgtcta ctaatatgat caatccattt gaaacatcgc tgttttcgca ataatcaagg
     9361 atttctgaag caatctgctg tggtgtgaca tctagtggca tatcaaatga ttcaaataga
     9421 tcctcttgta ataaacgatt tactacattt gccatactgc tagcagttgc ataaccgtga
     9481 gcagcaatca tcgcttttgg cagtcgtttt tcttttgacc atttcgcttt ttttagatag
     9541 atcgtcagta aaatccgatc catacttgtg tcttcaatat ctaatttgat cttacttaat
     9601 tccagaattc gttggacata gtgataacta gatggataag actgagaaac ttgttgttct
     9661 aattctttga ttagttggat aatatcatgt tcttccggta accatttgat agtgcttcgc
     9721 tgatagagat agtaactcaa ggcatagaca ctgtttccat cgaatttgat ttgataggca
     9781 gtttccattt gtcgaaaggt ctctcggata gattgtgtcc aataaaccag cagctcgtgt
     9841 ttttcttgtc tactggtctc aaacagcaaa aaatcaaata attgaatcac ttcttgcttt
     9901 aattttcctt cgcaagaata tagcagacag ttatttttct tgaaatcaat taggatttgc
     9961 tcaaaacttt taacgattcg ctgctgttcg ggctgttgct tctccattaa ttgctctaag
    10021 gtctggtctt gcgtaatata gattccttgc tgtgctgtat ttttagtaat aggctgcgca
    10081 agtagttctt tttgcaaatg atggatcgtg acatggattt caggctgttc acgctgttca
    10141 gcatatgctt ttgctgctga aactttgacg atatttttca gctctcctat gtttccggat
    10201 aatttctgac ttgttaaaag tgacaaagct ggtccactga ctgacaaagg gctccccatt
    10261 tttctttgtt cttcgagaaa aaaagagtaa atcagttcta gccgttcatt acgactacgc
    10321 tgattaagtg caggtagttc gattcggata ggtattcttc gaatgaaagt tgttaagaaa
    10381 tgactagtaa tctcttcagt cgtagcaaaa aagagacgtg ttttgatccg gcgtgacaaa
    10441 ttaggttctc ccatacgata aatcacacct tgatcaagat aggtgaacag tttttcctga
    10501 ccttctggtg ttaagcgatg tacctcgtct aaaaacaaga tcccaccatc tgctgcttca
    10561 aaagcccctt ttttattttc ttctgcacca gtgtacgctc ccttaacatg tccaaacaaa
    10621 ttgctagtca aaagttcagg attatctgca tattgtgcac aattaaaagt gatgaatggt
    10681 gcagaatctt ctagcagatc atgaagcaga caatactgat agaccaaatt aactaaataa
    10741 cttttacctg tgccactttc gcctgtaatc aaaagtggta atccgccatc tggatagtaa
    10801 agagctgttt tgatttgttc gatactttct ttcaaactgg cgtcgtatcc gatcataaaa
    10861 gagaataagt cttttggttg cgcgaaaaaa ggctgttcct ctttgagatc atcgatagaa
    10921 aaataaaaat tcgtgcgtaa cttaaaaaat tgtttttcaa aagcttcttt gtggaaataa
    10981 atcactggtc gagaattgat tttgactagt agttgctcat catttaactg gttcaaataa
    11041 tgactgactg tgtttctttt taccccaaaa tgatcagcta acctttgtgc tgtaaagacc
    11101 tcgttcatat gttctaaatc gaaaaaggct gtctggttct ctaagtaaca taaaatttcc
    11161 ttcttcaaca acttattcac ccctcctcca tcatagaaaa cggattcatt ttgtcaataa
    11221 aatctttaat aaagaattga aaaatatatc ttattataga cagcagccta cttatccctt
    11281 ataattttta ttctaaaaaa cgtacagttc cttccagttt ttatactgga atttcaacat
    11341 atgaaagaat aaggaggcta tgactattca atgaaatcgg ataaatataa aaacaggaaa
    11401 catacttcct ggaaaacttt tcgagaaatc atcggatctt atctcgctgt agttgtattt
    11461 ttgcctttgc tttatatggc tatgacagaa caaactcgtt ttattggcgt agatacgcaa
    11521 tatatagccg aaacaggatt tttattcatc tttatcttga tttttgcgtt ctataaatcc
    11581 ttccatacaa aataagattc acagatttca actttcctgt ctgtttttag ctattacaaa
    11641 tccttatatg tggtataaca acaatttatt ggcataatga ggaaaaacga gttatgatgc
    11701 tttcagagag taaagaggta ctgttgtcac catccttttt attgattacg tacaccactc
    11761 ttagtttttt cccattgatt acgaaaacaa ggtagaaaca ttgatgttcc taccttgttt
    11821 tcttttttta ttttcagatc aaaatctcaa gtagcttttg acttgatgtc gggaggttgt
    11881 cttcgttcca tcaaacctga tagaatctgc gccaaaccat agttttctcc actattattt
    11941 attcctctaa gatagtaccc acaataaacg aataaatatt tttctcattt tcatactcct
    12001 tctttgaaaa tcaattagat ttctctcaac ccactttttt acaaaaatta cgtagcaaaa
    12061 aagattgcaa gaacaaatta aaaaagaagt aaatagagtt tcatctataa acatttactt
    12121 gatatatttt ttatgcagaa ttcatttata gaaaaattaa gtaaaataga cgttcctatg
    12181 aatgaagaga ctggcatgtt ttctcatttt ctttttttta aaaaaaatag tctattcaat
    12241 ttctaaagct tcttcataat aaaactttca tttatgaaaa ggcttgttct cttttcattc
    12301 taaatttcct aagctacaat gtggtagtac ttgttttttc aattgtggac aaataaataa
    12361 taggaggaat catatgattc agttattacg ttatgcaaaa gactatcgta agcaaatcat
    12421 tttgggcccg ttcttcaaat ttcttgaagc tgtcttcgaa cttgtcctgc ctttaatgat
    12481 ggcttccttg atcgataatg gactaaaaat gaatgaccga ggaaaaatca ttgaaatggg
    12541 cttatggatg gtcgctatgt ctgtgattgg tctgatttgt gctatcattt gccaatacta
    12601 tgcttcagta gcttcacaag gatttggtac agagttacgt aatcagctaa tcaaaaaaat
    12661 caatactttc tctcacaacg agttgaatca ttttggaaca gataccttga tcacccgaat
    12721 gacaaacgac atcaatcagc ttcagctagc tttagcaatg gtcattcgtt tattgatcag
    12781 agcaccgttt ttaagtatcg ggtcagtggt catggctttt gtgatcgact gggaagtagg
    12841 tctgtttttc ttagcattat tgcctatttt ctcaatcatt ttatttttta tcatcaaaaa
    12901 aaccgttcct ctctaccaaa aagtgcaaga aaaactagat cagctcaatg aacacgttag
    12961 tcagaatctt agcggtgttc gtgtcatccg cgcatttgcg cagacaaaaa aagaaacaga
    13021 gaagttcgat aaaagcacaa atgatctagc gaacaattat ttacgtgttt ccaatatctc
    13081 tgccctatta tcacctgcta caaccttgat catgaatgtc gggatcatct gtttgctgac
    13141 agttggcggg atcaaagtaa atattggtag cttgcaacaa ggacaagttc ttgctttgat
    13201 caattatatg aatcaaatgc ttttggcact gatcgttgtt tcaaacctcg tcgtgatctt
    13261 cacacgtgcc gaagcttcag gaaatcgggt gaaagaggtg ctagacacag aaaattcgat
    13321 tcttgaagct gaggtcagta ctactcccga tttttcttct gaagcaatta tcgcttttga
    13381 ccatgttgac ttccgttata ctcctgattc tggtctttct ctccaaaata ttacatttca
    13441 gctgaagcga aatacagtcc ttggaatcat tggtccaacc ggaagcggga aaacgacttt
    13501 gacacaattg attccgcgtt tctatgatgt cagttccggt acagttataa tggacggaat
    13561 ggatgttcgt tcttggcagc tggatcatct ccgtcagcaa attgctcttg ttccccaaac
    13621 ttctgtacta tttaccggga ctattcgtga aaaccttcaa tggggtaaga aagacgccac
    13681 agaaaaagaa tgttgggaag ctctgaaaat cgctcaggca gaagaatttg tccgtcagct
    13741 tccaaatggt ttagatacaa aagtcatgga aaatgggaaa aatttctctg gcggacaaaa
    13801 acagcgactg acgattgcaa gagctttgat tgccaagcca gcattactga ttttagatga
    13861 ctctttaagt gcgttggatt atcaaacaga cttggatttg cgtaaggcgc tacagactta
    13921 tcttggcagt acagtgatta ttatctccca acgtgtccgc tctattcaag aagcacatca
    13981 tatcttagtg atggatcaag gtaagattgc tgctcagggt acccatgaag aattacttgc
    14041 tcaatcagca gaatatcagg aaatcgtcgc atcacaggag gaagaatagt tatgaaagta
    14101 aaaaaattat ccttgcagac gctccgccga ttcattcctt accttactgc ctatgcaaaa
    14161 gacatttggc tagctgtgat actaggaatc atcaatggga ttgcaacagt tgtgatgacg
    14221 ttacaaattg gtcaaagtat cgatcaaatg attggagaag gacaggtccg cttcaatcga
    14281 ctgttccatt tacttattct attcggtggt atcgttttaa tcaacgtagt cagtcaatgg
    14341 ctcatccaag tgttaagcaa tcggttagct tacttatccg ttgcaaaatt aagaaaagat
    14401 gcatttgctc atctgaatcg attgccactt cgttattatg atcaaaactc ccacggaaat
    14461 atcgtcagtc gatttacaaa tgatatggac aatatttcca ttgcaatttc tgcggccttc
    14521 aatcaattat tttctggagt ggcaatcatc attctttcgt ttatttttat gatgcgtcta
    14581 agtccacttc tgacattggt cgttctttgt tctacaccaa ttattttcct tgtgagttgg
    14641 atcgttgctc gtgcttcaca aacaaatttc gatagacagc aaaggattat tggggatatc
    14701 tcgggctttg tgaccgaacg aatcggtaac cagaaaatcg tgaaagcttt tcagcaagaa
    14761 gaagctagtc aacagcaatt tgaactgcta aatgctgatc tatatgaaaa aggacaacgg
    14821 gcacaatttt cttcttcctt gacaaacccg tcttctcgtt ttgtagatca ccttgcttat
    14881 ttatcgattg gtttagttgg cggcctattg gcattgaaga gtggttcgtc aatcactgtt
    14941 ggtgtgattt ccagctttac gatctactca agtcagtttt ctaaaccatt tatcgaactt
    15001 tctggaatca cgacacaact gcaaaccgct ttttctggtc tagaacgagc atttgatttg
    15061 atcgatcagc cagaagaaaa gcctgatttg ccagatgcct atgccttgga acccaaaaat
    15121 atcaaaggaa aagtctcttt tgatcatgtt tctttttctt atgaccccaa gcagcgtttg
    15181 atcgaagatt tcaattttac tgcttatcca ggtcaaacca ttgctatagt aggaaaaaca
    15241 ggggccggaa aatccacact tgttaatttg ctgatgcgtt tttatgacac aacaaaagga
    15301 acaattacag tcgatgacca tgacatccgc tctatccaac gtgatacatt acgtaaaagt
    15361 tttggaatgg tgttacaaga tacttggcta tttgacagta cattgcgaga aaatcttcgt
    15421 tttgggaatc cggaagcaag tgacgcagaa atcaatgatg ccctaaaagc ctcttatatg
    15481 tatgaatttg tagaacgttt gccggaaaaa ttagatacta agattggcgg tcaagggtta
    15541 aagatatcag atggacaacg ccaactgttg acgattgctc gaacgatgat cagtaatccc
    15601 cctatgttga tcttagatga agctaccagc tcagtcgata cattgacaga gaaaaaaatc
    15661 caacaagcct tcttagcaat gatggaagga aaaaccagtt ttgtgattgc ccatcgcctg
    15721 tccacaatca aaaatgcgga ccagatatta gtgatggatc agggagctat tgtcgaaatg
    15781 ggcacccatg atgagctgct tcaaaaagat ggttattacc gacggctcta tcaagcacaa
    15841 ttcacagcac aataaaaaca agcagtcttc tgggatggga agactgcttg ttttttaggc
    15901 tctatacttt ttgatgttgg tgaacttcac ca
//
LOCUS       DAPBBV010000056        15860 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.056, whole genome shotgun sequence.
ACCESSION   DAPBBV010000056 DAPBBV010000000
VERSION     DAPBBV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.056"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(12..482)
                     /locus_tag="RD486_002374"
     CDS             complement(12..482)
                     /locus_tag="RD486_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HDT7664089.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="RD486_002375"
     CDS             complement(641..1099)
                     /locus_tag="RD486_002375"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDT7664090.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="RD486_002376"
     CDS             complement(1270..2415)
                     /locus_tag="RD486_002376"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HDT7664091.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKRDEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="RD486_002377"
     CDS             complement(2428..3345)
                     /locus_tag="RD486_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDT7664092.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="RD486_002378"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="RD486_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDT7664093.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4437..4607
                     /locus_tag="RD486_002379"
     CDS             4437..4607
                     /locus_tag="RD486_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664094.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4822..6081
                     /gene="lysA"
                     /locus_tag="RD486_002380"
     CDS             4822..6081
                     /gene="lysA"
                     /locus_tag="RD486_002380"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDT7664095.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6068..6868
                     /gene="dapF"
                     /locus_tag="RD486_002381"
     CDS             6068..6868
                     /gene="dapF"
                     /locus_tag="RD486_002381"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDT7664096.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6871..7752
                     /locus_tag="RD486_002382"
     CDS             6871..7752
                     /locus_tag="RD486_002382"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDT7664097.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7749..8465
                     /locus_tag="RD486_002383"
     CDS             7749..8465
                     /locus_tag="RD486_002383"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDT7664098.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8471..9166
                     /gene="dapD"
                     /locus_tag="RD486_002384"
     CDS             8471..9166
                     /gene="dapD"
                     /locus_tag="RD486_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDT7664099.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9182..10183
                     /locus_tag="RD486_002385"
     CDS             9182..10183
                     /locus_tag="RD486_002385"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDT7664100.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10180..11541
                     /locus_tag="RD486_002386"
     CDS             10180..11541
                     /locus_tag="RD486_002386"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDT7664101.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11501..12652
                     /locus_tag="RD486_002387"
     CDS             11501..12652
                     /locus_tag="RD486_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDT7664102.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12627..13796
                     /locus_tag="RD486_002388"
     CDS             12627..13796
                     /locus_tag="RD486_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7664103.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13971..15350
                     /locus_tag="RD486_002389"
     CDS             13971..15350
                     /locus_tag="RD486_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7664104.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15631..15860
                     /locus_tag="RD486_002390"
                     /pseudo
     CDS             15631..15860
                     /locus_tag="RD486_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5186 a         2799 c         3378 g         4497 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcatctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa attttgttta
     4741 atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa acggaaaaaa
     4801 agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac agcaagcaca
     4861 ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat gagacaaacg
     4921 atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt gctttacgcc
     4981 tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg attcgggcta
     5041 gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc tagagatact
     5101 atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact tgaaaatgat
     5161 ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga attaagccaa
     5221 cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga agcacatact
     5281 catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa
     5341 gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt agaaggattt
     5401 catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga aatcgacaaa
     5461 ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg cggagggttt
     5521 gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact aaaaaaactg
     5581 attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca attactgatc
     5641 gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat tggtttcatc
     5701 aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga taatatccgt
     5761 ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc ggaagaaaaa
     5821 acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa
     5881 gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac gggagcttat
     5941 ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt ttttgtcaat
     6001 aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact aaggggggaa
     6061 gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct tattagatta
     6121 cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag aaaaatatga
     6181 tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt acaacaaaga
     6241 tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat acgtaaatga
     6301 tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca caagaaaaat
     6361 tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc cagatgattc
     6421 tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa tagagatcaa
     6481 tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg ttgtttttgt
     6541 tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc atcatccttt
     6601 gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag aattgatcgt
     6661 ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt gctgtgcctc
     6721 ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg ttcacttgga
     6781 acaaggagac ttgatgatct ctggtgagga tgcgatacaa atggctggcc cagcagttca
     6841 tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt ggcgctgatc
     6901 acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt gatccaattc
     6961 catttagatg aacaaacaga tggattatta gttttaggta caacaggaga atcttctacg
     7021 ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt ggctggccgt
     7081 gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga aaaagcgaag
     7141 cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta caacaaaaca
     7201 agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc gattccgctt
     7261 attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt attagtaaat
     7321 ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat ggcttatgtg
     7381 atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa tgatgatttg
     7441 atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa
     7501 cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca gcaagcaaaa
     7561 gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac caatcctatt
     7621 cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg cctgccttta
     7681 gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg
     7741 gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga gtcgaagaag
     7801 ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa gaagcaacta
     7861 cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca gataatttag
     7921 agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc acgacaggtt
     7981 atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct gtgatgtata
     8041 gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa gcagctgcaa
     8101 tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa aaagatgcac
     8161 catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg
     8221 tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac agtattcgtg
     8281 caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa atatttacga
     8341 tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa gcagcggact
     8401 ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg gacaaagggg
     8461 tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat ctaaaaagac
     8521 gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt
     8581 tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc cggttttaga
     8641 agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat acagcgcagt
     8701 tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga
     8761 tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca atattggtgc
     8821 agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac gagcgacagt
     8881 gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc
     8941 ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag tgattgttga
     9001 aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt tagaagatgt
     9061 ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca
     9121 gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga gatggagaaa
     9181 aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct
     9241 caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag cttcaaaacg
     9301 ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg aattgacaga
     9361 aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg tatccaaaga
     9421 gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct cagcatggcg
     9481 ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact atacattgaa
     9541 tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc ttaaagcttt
     9601 acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag tttctggttc
     9661 cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac cagttttgta
     9721 tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg aaaatgggta
     9781 tacaaaagaa gaacagaaaa tgataaatga gacccgtaag attctgcatc agcctgcttt
     9841 gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc
     9901 agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca gccagtttcc
     9961 agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca ttcttgctag
    10021 aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag agaacggatt
    10081 gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg ccgtacagat
    10141 tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac gctgaaagta
    10201 gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt
    10261 gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca
    10321 gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca gcatcatgtt
    10381 gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag agatgttctt
    10441 gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact ggaagacgaa
    10501 aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca actgatggct
    10561 gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga ctatgatggg
    10621 aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag atatccgaaa
    10681 atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt attgggccgt
    10741 gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga aagttatgag
    10801 aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga tcatcctaaa
    10861 atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg ggctaacgtt
    10921 cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca aataaaaaat
    10981 accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga aaaggaaaat
    11041 ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt caaacgtcat
    11101 atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa acatgagata
    11161 tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc agcagaagcg
    11221 attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg cgtggaagaa
    11281 atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca taaagaattg
    11341 attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg cacatcgatc
    11401 ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa tcaatatgaa
    11461 acagtagtga agggtatcta cgaagggatg gtgaatacgg atgctgaaag aatatcgaat
    11521 ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa aatatttata
    11581 tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag gactactcct
    11641 ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg atgcactgcc
    11701 agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata tgcatgcatg
    11761 tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa ctaaacacat
    11821 tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa tttccggtgg
    11881 cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag caatatttgg
    11941 ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag gacctttgat
    12001 ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata ttgcttctag
    12061 tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg tttatgattt
    12121 tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa tccaaggtgg
    12181 aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc gttcttacag
    12241 ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac agtttcactc
    12301 tacagctact atttcttttc gctataatga cggctatcca gctgtaatca accatagagg
    12361 cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc cagttcttca
    12421 agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct ttttaggtgt
    12481 cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg ttttagaaaa
    12541 tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa aaatcgatag
    12601 cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt agtcctaggc
    12661 tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg tcgataccag
    12721 atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat gtcaagcaag
    12781 caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga ggattagagg
    12841 aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact tatgatccgc
    12901 aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg
    12961 ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga tatcagccat
    13021 tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca gggtttgtct
    13081 gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc aaagcagtca
    13141 ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa
    13201 tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta tatgctgaat
    13261 tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa acaatcgtga
    13321 taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt atttttgctc
    13381 aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact gccgctacaa
    13441 cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat agcgagaata
    13501 tgaaagagca atatcaaaca cgaagagatt atctggtcca gcaattggcg cctttaggat
    13561 ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca gctgccattc
    13621 aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc
    13681 caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat gctagcagca
    13741 tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa cagtgattca
    13801 tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg agacgattgt
    13861 tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg taatgttaag
    13921 tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca atggaaaaaa
    13981 tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg gaactattga
    14041 cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat atttccttca
    14101 tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat gatgtacgta
    14161 atttcagacc agaaaacttt ccgcaatcca atgttcatat tttaaataat cacgaagtaa
    14221 aaacgatcga tgccgataaa aaaacagtaa cggttactag cgcatcagat aacgaaacaa
    14281 aagaatatcc ttatgacaaa ttgattttga gttctggtgt caaaccaaac aatctgccag
    14341 taccaggagc agatctagaa aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa
    14401 tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca
    14461 ttgggatcga agcagcagaa gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg
    14521 tgatcgatag acctttaggc acttatttag atgctgagat gacagatatt ttagaacaac
    14581 acctaaatga aaacggtatt gaagttttga caaatgcaaa aatcgaagct tttactggta
    14641 acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat cccagcagat ctagtcattc
    14701 aagctgccgg tgtgaaggca aatacagaat ggttaaaagg gatcgtcgac ttagatgaac
    14761 gtggctggat ccaaacaaat gaatacttgc aaacgaatct tccagatgtg tatgcagtag
    14821 gagatgctac acttgcttat tctatcccag cacgcaaaaa aatgccgatc gctttagcga
    14881 ctgttgcacg tagagaagca cgttatgtag taaaacatct ttttgaagaa gtaccaaaca
    14941 aaccgttcgg cggagtcgta ggttcctctg cattaagtgt ctttgactat cattttgcag
    15001 caagcggatt gaatagcttt acagcagcaa aagcaggagt agatgtacga gtgtcttatt
    15061 atgaagatac gttacgacca aaatatgtac cagaagaaca aggaaatcca aaagtgtcca
    15121 tccaattatt ctcggatcca atgacccatc aattgctagg aggagcagta ttatctacct
    15181 atgatgttac aggtcaagga aatgtattgg cactagcgat ccaaaacaaa ctgactttag
    15241 aagaactagc agaagctgac ttcttcttcc agccaggctt tgaccgacaa tggagcatgt
    15301 tgaatctagc cgctcaacaa gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa
    15361 tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag taataagaac agccaagtaa
    15421 aaacagcttc ttatgttttt aacttggctg gacttattac cgcagatgca agcttttgaa
    15481 caccgtttat tttcaaaaaa gggactgtga cacgatttgt gtaccgaccc ccaaaagtta
    15541 gaccaaaaaa tctaactttt ggaggtcggt attttttatg gttaaatata cttttgaact
    15601 taaattaaag atcgttcatg attatttgga tggcaaaggc gattggaccg taaaaatcca
    15661 gatcaagaga ttgaagcgga aatgcttaaa attcgggaga agcacaagga ttatggctgt
    15721 ttacggatga ccaatgaact aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag
    15781 cgcttgatca agaagctagg aataaaagta acggcataca cgcgtaaatc acgtcgctac
    15841 aattcttatc gaggaaaagt
//
LOCUS       DAPBBV010000057        15243 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.057, whole genome shotgun sequence.
ACCESSION   DAPBBV010000057 DAPBBV010000000
VERSION     DAPBBV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.057"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            168..362
                     /locus_tag="RD486_002391"
     CDS             168..362
                     /locus_tag="RD486_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664105.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="RD486_002392"
     CDS             631..930
                     /locus_tag="RD486_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664106.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="RD486_002393"
     CDS             complement(1027..1461)
                     /locus_tag="RD486_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7664107.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="RD486_002394"
     CDS             complement(1693..2403)
                     /locus_tag="RD486_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDT7664108.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="RD486_002395"
     CDS             complement(2393..3253)
                     /locus_tag="RD486_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HDT7664109.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="RD486_002396"
     CDS             complement(3258..3896)
                     /locus_tag="RD486_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDT7664110.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="RD486_002397"
     CDS             complement(3911..4210)
                     /locus_tag="RD486_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7664111.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="RD486_002398"
     CDS             complement(4253..5737)
                     /locus_tag="RD486_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDT7664112.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="RD486_002399"
     CDS             complement(5757..6218)
                     /locus_tag="RD486_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7664113.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="RD486_002400"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="RD486_002400"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HDT7664114.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="RD486_002401"
     CDS             7521..8291
                     /locus_tag="RD486_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7664115.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="RD486_002402"
     CDS             complement(8564..9391)
                     /locus_tag="RD486_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7664116.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="RD486_002403"
     CDS             9959..11194
                     /locus_tag="RD486_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDT7664117.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="RD486_002404"
     CDS             complement(12193..12453)
                     /locus_tag="RD486_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDT7664118.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVTHLNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="RD486_002405"
     CDS             complement(12480..13781)
                     /locus_tag="RD486_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7664119.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="RD486_002406"
     CDS             complement(14073..14531)
                     /locus_tag="RD486_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7664120.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..>15243)
                     /locus_tag="RD486_002407"
     CDS             complement(14544..>15243)
                     /locus_tag="RD486_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HDT7664121.1"
                     /translation="KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITK
                     NFPSNIPNNYLEYYLYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVL
                     NFNFGEHGQYIVDIAISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEP
                     ITLRKPISDFHKGLMEAQVAVEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILD
                     EMIKVNKKYWPALK"
BASE COUNT         4876 a         3105 c         2365 g         4897 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgcccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatacttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcaaatgcgt
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacgac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 tta
//
LOCUS       DAPBBV010000058        13969 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.058, whole genome shotgun sequence.
ACCESSION   DAPBBV010000058 DAPBBV010000000
VERSION     DAPBBV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.058"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(325..2322)
                     /gene="tkt"
                     /locus_tag="RD486_002408"
     CDS             complement(325..2322)
                     /gene="tkt"
                     /locus_tag="RD486_002408"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDT7664122.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2424..2675)
                     /locus_tag="RD486_002409"
     CDS             complement(2424..2675)
                     /locus_tag="RD486_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HDT7664123.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2822..3445
                     /gene="lexA"
                     /locus_tag="RD486_002410"
     CDS             2822..3445
                     /gene="lexA"
                     /locus_tag="RD486_002410"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDT7664124.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3624..3842
                     /locus_tag="RD486_002411"
     CDS             3624..3842
                     /locus_tag="RD486_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664125.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4130..4642)
                     /locus_tag="RD486_002412"
     CDS             complement(4130..4642)
                     /locus_tag="RD486_002412"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDT7664126.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="RD486_002413"
     CDS             complement(4656..6953)
                     /gene="recJ"
                     /locus_tag="RD486_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDT7664127.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7095..7538)
                     /locus_tag="RD486_002414"
     CDS             complement(7095..7538)
                     /locus_tag="RD486_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HDT7664128.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7539..8327)
                     /locus_tag="RD486_002415"
     CDS             complement(7539..8327)
                     /locus_tag="RD486_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7664129.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8324..9265)
                     /locus_tag="RD486_002416"
     CDS             complement(8324..9265)
                     /locus_tag="RD486_002416"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDT7664130.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9442..10029)
                     /locus_tag="RD486_002417"
     CDS             complement(9442..10029)
                     /locus_tag="RD486_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HDT7664131.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10250..11557)
                     /gene="obgE"
                     /locus_tag="RD486_002418"
     CDS             complement(10250..11557)
                     /gene="obgE"
                     /locus_tag="RD486_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDT7664132.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11851..12861
                     /gene="gap"
                     /locus_tag="RD486_002419"
     CDS             11851..12861
                     /gene="gap"
                     /locus_tag="RD486_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDT7664133.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12946..13881)
                     /locus_tag="RD486_002420"
     CDS             complement(12946..13881)
                     /locus_tag="RD486_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7664134.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3856 a         3130 c         2455 g         4528 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acaaacttaa ttaattaaat tatactttta attctcaaga aacacaaact
      181 aatccgaaga attctttgtt ttgtcattta aatgtaacat agccgaaaac gaaaagtaat
      241 attgatttat tcttctaaca cataaagaac agctgtctcc aacttgcaga cagctgttct
      301 tatcagtcaa acaattgctt ggatctatga tagttgattg tacgtattca cgacattttc
      361 tactgtaaat ccaaattctt ctaaaatttt agtgccaggg gcagatgcac cgaaatgatc
      421 gattgtaatc gttgcgccct ctgttcctac gtagcgttcc caaccaaatg atgcagcagc
      481 ttcgatagcc acacgtttct tcactgattt aggaagtaca ctttctttat attcagaaga
      541 ttgtttttca aagaggtcaa agcttggcat agaaacaaca gaaacatctt tgcctttttc
      601 agccaattct ttttgagctt tcacagccaa atcaacttca gaacctgttg caatcaaaat
      661 accttctggt gtttctcctt gtgatggaga aagaacatac gcgccttttt tcaccatttc
      721 atctgctact tcttttgtag aaggcaatac tggaaggttt tgacgactca atacaaggat
      781 agtaggcgca tctgttgtct ccatcgctac tttccaagca gcacgtgttt catttccgtc
      841 tgccggacga atcacttgaa caccaggcat gcagcgaaca gatgctagtt gttcaatcgg
      901 ttcgtgcgtt ggtccgtctt ctccgacagc aaccgagtca tgtgttaaga cgtaaacaac
      961 aggagtatgt tggattgctg ctaaacgaac tgctggtctt agataatcga caaagacaaa
     1021 gaatgttcca ccgtagatac gagttccgcc atgaagttgg ataccattca tagccgaagc
     1081 cattgcaaat tcgcggacac cgaaccagat gttgcgtcct tcataatgtt caggagtgaa
     1141 atctttatct gcagccacca ttgtattatt ggaacctgac aagtccgctg aaccacccca
     1201 gaagcttggt atagctttcg ataattcttg gatgacttct ttacttgaaa cacggcttgc
     1261 ttgactgctt ccaacttcat aagttggcaa ttctgcatcc cagttttctg gtagtttgcc
     1321 atcaaaagca tcttcaaatt gttgtgctaa ttcaggataa gcttttttat aattggcaaa
     1381 catttcattc catgcatctt cagctttttg tccttcttct atcatcgttt gatggaagcg
     1441 ggcagctact tcttctggaa cagtgaaatc tggatactcc caaccataaa cttctttagc
     1501 catcttgatg ccatcttcac caataggagc accatgaaca gcagatgttc cttctttagg
     1561 agcaccatag ccgatgactg tttttacttc gatcaatgtt ggtttgtctg tttcagcttt
     1621 tgcttcttca atcgctttag agattgcttc taggtcattt ccgtctttca ctaagatatg
     1681 ttgccagcca tatgcttcat agcgagcacc aacgttttct gtgaaagctt ttgaagttgg
     1741 accgtctagt gaaatatcgt ttgaatcgta taaaacgatc aatttcccta gtttcatatg
     1801 acctgccatc gaacttgctt cttgagatac cccttccatc aagtctccgt caccgcatat
     1861 tgcatacgta tagtgatcca tcacattaaa gttttctttg ttatacgttg ctgcaaggtg
     1921 cgcttctgcc attgccatac cgacagccat tgcaatccct tgtcctaatg gccctgtagt
     1981 ggcttctaca ccatctgtgt gatgtacttc aggatgtcct ggtgttttag aatcccattg
     2041 acggaattgt ttcaaatcat cgattgtcac ttgatagcca gctaaatgaa gcaagctata
     2101 caacattgct gacccatgtc ctgccgaaag aacgaaacgg tcgcggtcag cccagttttt
     2161 tgatgtcgtt ggatttactt tcaggtgttt tgtccataac gcatatgcca taggtgctgc
     2221 gcccatcggc aatccaggat gtcctgagtt tgctttttgg actgcttcaa tacttaatgt
     2281 acgaattgtg ttaacgccaa gttggtcaat tttgtcaaac aaaataaccc ctcctattaa
     2341 tttaggtttt ttttaccttt atttcttaca ctttcattct ataagatgtc acacgaaaaa
     2401 gcaatctttt tcagtatttt ttactaaaag ttgtcatttc ggttgtgtaa gccttttttc
     2461 ttttggattt cttttaattt ttccggggtc acgtcattgc cctcaggatc gacgactttc
     2521 attccttcga tatgatgacg cataccggaa cgaaaagctt ccaaatactc tttgcgtaag
     2581 ttgatttgtt cttgttcttc ggcttttgag agaccatttt ccttcttttt acgtgcaagt
     2641 tcattgatcc tctctatttt ttcaggtgac agcatgctca gccctccttt tactctcctt
     2701 catattatat aaaaactgaa aaaaaaacaa ctagataaac taaataaaat acgaacattc
     2761 gtttgattta gcgcttttta tatggtacta tttatttatc aagtgaaaga aggtgtacct
     2821 tgtggcccga caaactgaat caagacaaat cgaagtctta cgatatatcc atgaacaagt
     2881 aacccaaaaa ggatacccgc cgactgtccg tgaaatcggg gaagctgttc agctttcttc
     2941 tacttctact gttcacggtc atcttgcacg gcttgaaaaa aaagggttta tccaaagaga
     3001 tccgacgaaa cctcgtgcaa tcgagttgac aaaacaaggt ttagaaaaga ttgggattcg
     3061 tccaacaact attccagtac ttggcgtcgt aacagctgga gaacccattt tagcagtaga
     3121 ggatgcttca gacttctttc caatccctcc taatctttct tccgaagaag gcagtctctt
     3181 tatgctgaca attcgtggag atagtatgat caatgctggg atcttggatg gtgacaacgt
     3241 gatcgttcgg aagcaagaaa ctgctcaaaa tggcgatatt gtcattgcaa tgactgccga
     3301 ggacgaagcg acttgcaaac gattctataa agaaaaaaac tttttccgtc tgcagcctga
     3361 aaacgacttg ctcgaaccaa tcatcttaga tcaagtatct atattaggac gagtagtagg
     3421 actttatcgt agtcatatct attaattgct actaataaaa gaaaactttt taaaaagagt
     3481 ttgagacgat ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc
     3541 acttccctct ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc
     3601 ataaattaac gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg
     3661 ttttgttttt aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg
     3721 ttccgttatt tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc
     3781 ggcgcagaat tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat
     3841 aataaggatt gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga
     3901 caaaaatcgg tcacatcctt ttttcgaata aacggtgttc taaagccagt ttttcggtat
     3961 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat
     4021 ttataaaaaa atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt
     4081 taaaatcgct tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca
     4141 ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga
     4201 tcaaaaatgc gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt
     4261 tgattgttcc tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa
     4321 tggcatcctt atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga
     4381 tggtttctcg aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat
     4441 aagcaacagg acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc
     4501 gtttttcttt tgcataattt acgatttgct tcgtagcttc ccgataagcg tcaccatctg
     4561 ccatcagtgg ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg
     4621 caatataatc ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg
     4681 gtaggaatat cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgccgctgg
     4741 tataatctgc tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg
     4801 ttctctattg taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt
     4861 tcagggatac gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct
     4921 tgagaatgga tcagtttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa
     4981 taggcctcat caggcgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa
     5041 acttctttca gatccgctaa atcatctgga caatccataa taactagaga gttcggtttt
     5101 cttttttcaa ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg
     5161 ataatctcag gcacgaattt caacgtagaa gaatcaaatg ctaaataaag gctaccttcc
     5221 gacgttcggc tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc
     5281 acagaaaaat cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa
     5341 agctttccta ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca
     5401 aaagcgaccg catcaagctg actcgatgca ttggaaagga caaatttcag atgctgttgg
     5461 tttgctccga ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa
     5521 ggattatccg taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact
     5581 tcatttggca gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga
     5641 tgatcgacta tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc
     5701 gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca
     5761 agcatttcaa aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct
     5821 tcttttaaag taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca
     5881 atgcccaaaa cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta
     5941 ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg
     6001 atctcattca atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac
     6061 gagacggcag gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa
     6121 aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc
     6181 tgaagtccta tccgttctga atgatgaatg gcattgattc ctaatgaaac aaggattcga
     6241 ttctcatcag tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat
     6301 tctacaggcg gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc
     6361 aaatctggaa atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct
     6421 ggtaaattct caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga
     6481 gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt
     6541 ccttcttcga tcttttcttg gtatacagat tggtttggtc catacccatg ctcaaatcga
     6601 tttggcagga atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt
     6661 gcactggtga tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt
     6721 acagcttctt ggattcggct gattgcttta tccatatcgt gcatcagata cggatcatgt
     6781 aattcttgtt cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt
     6841 tgccacagta acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag
     6901 gattcagaag gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca
     6961 ctcctaactt agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa
     7021 aaacagatca gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt
     7081 atgaaatatc cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt
     7141 tcttccggcg ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa
     7201 gcagcttcca actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct
     7261 tcaattttct tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt
     7321 tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc
     7381 agcgcagaac cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt
     7441 acaggaacat ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat
     7501 ccaagaatca cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg
     7561 ctggctaaat aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa
     7621 ataaacggtt gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc
     7681 aacttggcag gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca
     7741 gccttatcga agaaatctgt ctcgattgga cctggattca ctgtcgtaac agctacgcca
     7801 agtggtttca attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca
     7861 gaataaaccg ttgattttgc agttgccatt tttccagcca tagacgcgat attaatgata
     7921 tgaccttgtc ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct
     7981 aagatgttga cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg
     8041 aaaatcccaa aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc
     8101 ttttcatata attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc
     8161 tctttgccgc tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt
     8221 gcgcaactta taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga
     8281 ccgcctgaac tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct
     8341 cgcgaaatgg aatctcaatg ctatcaaaat ctttcatgat cgtcgtgttt tcaaacactt
     8401 cttgtgcttc tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag
     8461 taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg
     8521 aatggaaata gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca
     8581 gaatatcgct attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa
     8641 tagtcacgat tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc
     8701 catcttctag ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa
     8761 tacctaattc ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac
     8821 gataaccaaa actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat
     8881 cagtaaaaat cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg
     8941 tttgcgaaat acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct
     9001 ctaatggcgt atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa
     9061 tatgatcgcc gtgtaaatgt gtaataaaaa ttttaccgat ttttctcgga cgaatagtcg
     9121 ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct
     9181 cgtctaaaag tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac
     9241 ctgttcctaa aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt
     9301 ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa
     9361 cgttctaaag cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt
     9421 gagatcctct gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt
     9481 ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc
     9541 tttcgcatca tgcacatctt tttcgacatc ttcataatcc aagcgggtaa tttctccgcc
     9601 taattccatc attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat
     9661 cagtcctgta gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc
     9721 ttttatttct ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa
     9781 aatccctagc ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga
     9841 tttgttatta ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg
     9901 atcatggctg acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt
     9961 gatttctgaa aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg
    10021 tttgctcatt aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgta
    10081 aaataagaaa agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta
    10141 tcacagctcc tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct
    10201 cccttaaatc tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa
    10261 attcaaattc aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa
    10321 gagcttcatc cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat
    10381 gatcgaaatt cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg
    10441 catctgaatc acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag
    10501 tttcttcttc cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg
    10561 ctgtagcatt caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg
    10621 ggatgtcatc agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta
    10681 gattttccgg tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta
    10741 gcaagcgtaa gttataagta gataattctt tgttgatggc aagatagtct tcataaggat
    10801 ctcgtccttc catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat
    10861 gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca
    10921 agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttagggacga
    10981 gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag
    11041 tcgatttccc gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta
    11101 gttcgatttt tcgctcttgt cctggttcgc cgttttcagc aatttccggt gcaggattcc
    11161 gaggagaggc aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg
    11221 tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg
    11281 ttccttgtgg tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca
    11341 tcccattttc acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac
    11401 gtaacccttc atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg
    11461 gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc
    11521 cagctttcac atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt
    11581 attcatttat ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta
    11641 tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt
    11701 ttatcatttg gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa
    11761 tattctttgc gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac
    11821 agcaccccta ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt
    11881 gggcgtattg gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta
    11941 gtagcaatca acgacttaac aagtccaact atgttagcac aattattgca atttgactct
    12001 actcatggta cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc
    12061 gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac
    12121 ggtgtagata tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg
    12181 catttagatg ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc
    12241 atcgtctata acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt
    12301 tcatgtacaa caaactgttt agcacctatg gcttatttct taaataatga atttgggatc
    12361 gaagttggta caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga
    12421 cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat
    12481 tctactggtg ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa
    12541 ggacacgcac aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg
    12601 aaaacaaaag taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat
    12661 ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa
    12721 ggttcgatct ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt
    12781 aaaactgttg catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta
    12841 gaaaaattcg ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat
    12901 ccagtcaaag gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg
    12961 gcttaaaaat tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc
    13021 atgctcggct ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt
    13081 atctaacatt tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg
    13141 ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac
    13201 ttttgtcact agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc
    13261 tagctgataa gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt
    13321 cacattatct ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac
    13381 accgtataga acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg
    13441 tacatagtct ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg
    13501 tcctcttgca tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt
    13561 ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt
    13621 cgtttcagca ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca
    13681 atcgcttcgg ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg
    13741 tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt
    13801 ataaaaataa ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag
    13861 gattttcatc caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg
    13921 aattagtata atcaaagaat ctctactatg caatgttcat ttttataac
//
LOCUS       DAPBBV010000059        13950 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.059, whole genome shotgun sequence.
ACCESSION   DAPBBV010000059 DAPBBV010000000
VERSION     DAPBBV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.059"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            137..310
                     /locus_tag="RD486_002421"
     CDS             137..310
                     /locus_tag="RD486_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664135.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            950..1423
                     /locus_tag="RD486_002422"
     CDS             950..1423
                     /locus_tag="RD486_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDT7664136.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1432..1659
                     /locus_tag="RD486_002423"
     CDS             1432..1659
                     /locus_tag="RD486_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7664137.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2295..2666
                     /locus_tag="RD486_002424"
     CDS             2295..2666
                     /locus_tag="RD486_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664138.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2922..3164)
                     /locus_tag="RD486_002425"
     CDS             complement(2922..3164)
                     /locus_tag="RD486_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7664139.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3196..4098)
                     /locus_tag="RD486_002426"
     CDS             complement(3196..4098)
                     /locus_tag="RD486_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7664140.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4111..4299)
                     /locus_tag="RD486_002427"
     CDS             complement(4111..4299)
                     /locus_tag="RD486_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDT7664141.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="RD486_002428"
     CDS             complement(4313..4876)
                     /gene="amaP"
                     /locus_tag="RD486_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDT7664142.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4914..5807)
                     /locus_tag="RD486_002429"
     CDS             complement(4914..5807)
                     /locus_tag="RD486_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7664143.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5885..6808)
                     /locus_tag="RD486_002430"
     CDS             complement(5885..6808)
                     /locus_tag="RD486_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7664144.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6857..7207)
                     /locus_tag="RD486_002431"
     CDS             complement(6857..7207)
                     /locus_tag="RD486_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7664145.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7240..8142)
                     /locus_tag="RD486_002432"
     CDS             complement(7240..8142)
                     /locus_tag="RD486_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDT7664146.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8135..8992)
                     /locus_tag="RD486_002433"
     CDS             complement(8135..8992)
                     /locus_tag="RD486_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDT7664147.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9326..10135
                     /locus_tag="RD486_002434"
     CDS             9326..10135
                     /locus_tag="RD486_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7664148.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10175..10672
                     /locus_tag="RD486_002435"
     CDS             10175..10672
                     /locus_tag="RD486_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7664149.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11057..11130)
                     /locus_tag="RD486_002436"
     tRNA            complement(11057..11130)
                     /locus_tag="RD486_002436"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11094..11096),aa:Ile,seq:cat)
     gene            11317..11640
                     /locus_tag="RD486_002437"
     CDS             11317..11640
                     /locus_tag="RD486_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664150.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11804..12058
                     /locus_tag="RD486_002438"
     CDS             11804..12058
                     /locus_tag="RD486_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664151.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12128..12373
                     /locus_tag="RD486_002439"
     CDS             12128..12373
                     /locus_tag="RD486_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7664152.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12449..12814
                     /locus_tag="RD486_002440"
     CDS             12449..12814
                     /locus_tag="RD486_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664153.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12875..13438)
                     /locus_tag="RD486_002441"
     CDS             complement(12875..13438)
                     /locus_tag="RD486_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664154.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4090 a         2577 c         2304 g         4979 t
ORIGIN      
        1 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
       61 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
      121 aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
      181 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
      241 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
      301 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
      361 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
      421 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
      481 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
      541 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
      601 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
      661 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
      721 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
      781 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
      841 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
      901 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
      961 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     1021 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     1081 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     1141 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     1201 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     1261 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     1321 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     1381 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     1441 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     1501 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     1561 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     1621 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     1681 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     1741 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     1801 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     1861 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     1921 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     1981 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     2041 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     2101 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     2161 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     2221 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     2281 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     2341 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     2401 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     2461 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     2521 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     2581 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     2641 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     2701 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     2761 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     2821 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     2881 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     2941 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     3001 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     3061 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     3121 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     3181 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     3241 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     3301 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     3361 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     3421 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     3481 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     3541 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     3601 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     3661 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     3721 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     3781 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     3841 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     3901 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
     3961 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
     4021 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
     4081 tttgttattg ttattcatgg atgtttcctc ctaagattta aaatagtgat ctaagatttt
     4141 cgtttgtttc agataaaaac cgatagcgac gccgatcgct gccatgatca agatcaataa
     4201 ggtcttgaaa aagcccacgg tgatccataa aacggctaat atcaatccaa gtaccccaaa
     4261 gatgataggg agcttgtatg tcgaaaatag ttctttcatt tttggtcccc ccctattcta
     4321 ctcgtttgcg gtcattgctt cgtttagctg gttcttcaaa gcctgtgtat ttcaccgata
     4381 ctttcactgg ctcttttgtt cccaatatgt gttgtacttc attttcgatt tctttcatca
     4441 atgttcctgt tttaccaatg agtgctgaag ttcgtttcaa ctcccctttt acattgacgg
     4501 cgatcttgtt tttcgttgct ttgacattta cttttggtga atggatgaat tcatcttcat
     4561 gcaagtgaga acgaaccatt ccttcaattg cttttttatc caacgtcaac tccccatcac
     4621 catgtttcag tagaaagttt ccgattgttt ttggataaaa caggaaaaca agtaacgtga
     4681 taattgtcaa aatagcaaat gcaacggcaa gccaaaatac atattgttgc acgtatgaat
     4741 tagtgatgga aaagaatcga aacttctcta gctgaaaagg caatggatag gttgcactta
     4801 atagtatcgc aaacaaaagc acagatagca aaagtaatgt tccgatcact ccgatcgttt
     4861 ttacaccttt attcattttc gcacctcctc ataggggtga aacgatcaac ttcttataag
     4921 ttgatcgctt ctccaccagt tactccgtaa atttgggctg taacataact tgctttattc
     4981 gatgctaaga aaacataaac tggtgctaat tctcctggct gacctgcacg ttctagtaaa
     5041 ctttgctgac caaattcagg gatcgaatca gaaggttgtc cttcgtctag ttgtaatggt
     5101 gtccagattg gaccaggtgc tacaccattt acacggattc ctttaggtgc aagctgtttt
     5161 gctaaaccga tcgtaaagtt agcgattgaa gcttttgttg ctgcgtaatc taataaatgt
     5221 tcgcttggat tgaatgcttg aacagaagtt gttgttacga ttgctcctcc tgctgggata
     5281 tgcggaacag cttctttcac taaagcaaac atagcgatga tgtttatcat aaatgtgtct
     5341 ttgacttgct caagtggtaa ctcagcaata gactgacaag aaatttgctg tcctgcgttt
     5401 agtaccatcg tatctagccc gccaagttca ctcacggctt tatctatgat ttctttaggt
     5461 gcttgttcgt cacgaagatc aaaaggtagt aagacaatct tacgtcctgc aactttcacg
     5521 tattttgcta cttcctctgc atctttttct tctcctggga agaattgaag agcgatatct
     5581 gccccttctc tagcaaatgc aatcgctgct gcacgaccga tccctgaatc tccaccagtg
     5641 attagtacac ggcggttttc tagttgatta ttgccttcat aggattcttc tccacaatca
     5701 ggaacaggaa tcatattctg ctgtaaagct ggtgtatcct gatcttgttt aggaaatttc
     5761 tccgtatggt acaagtttcg cgggtcgatt aattttggtt ctgtcattgc tgtattcctc
     5821 ctagttttta aattgtattg ccaaaacaaa tttctttgtt tgatacctgt tttaaataga
     5881 ttctttaatt tgtataatct ttccggtata aatggtaacc taaaactact gctgctatca
     5941 aagagccaaa gactacgagt ataaagccta gagcagaact tttacccggt aatcctcctg
     6001 tattcattcc ccaaatccct gcgaacaacg ccggaacgga aatgattaat gcagctgaat
     6061 ctagatattt catgatatga tttagattat tgtccatcat cccgttgaat agatcaccaa
     6121 tactctctaa taaatctcga tagatctcga tcattttttc tgtttgtcgc tgtctcaaat
     6181 ggacatcata gagtagctgt tcatcgtcta aacgtttgat gaaagtttca gaattccata
     6241 attgatccat tgtttcccgt tgatctctta aggtatgatc gatatatacg atgtctcttt
     6301 caagatctgc ctgtttatac agttcttcat tttccgttgt tttacgagct gctttatcca
     6361 aagcgtcaat tcgctttttc atctctctta gttctttcac gtaatgggtg taaatatcta
     6421 ataatgtata cgtgatgatc ttttcaaacg agtttaaatg atttccatgc tttgtcagca
     6481 gccgatccac aaattcggtt tttctatcga tacaagtaat caagagatta tcggaaagta
     6541 caaaagatat tggcgttaat tttttttcga tacgattatc tgactgatct agattaatca
     6601 ctaccaaaga aaatggatgc tctagtttcg tctcataaag gcgctccatc cgagaaactt
     6661 cttccggata ttcggttcct acgaaaatat catcaggaag ctcgaattct tcgattgctt
     6721 gctcaatctc ttcgggcttt gcactatcaa gtacgagcca attatatttt ttttcatctg
     6781 tttctattac attcttttct tcatccacaa agtagtatct caatgtatac ctcctttttg
     6841 gactttctcg aaactattag ctgaagaagc agttctttaa tttgatatta taatcgagta
     6901 ctgcgatttc attttctaat gaaaagctgt caagctgttt gttgaagtcc atgttcaatc
     6961 gtttaccgaa ataattttgc tctaatttag atgtatagat gtccaataat ggatgctcga
     7021 ttttagtcgc atattctcca aattccgaaa caaaaggaat gatttgaaaa aagctgcctt
     7081 ttgcaaaagc acctttgtcc cttagaaatg gatcggaatc attgataagc gcgagtgcga
     7141 tttttgtatt ttccccaacc ttttcaatta acgtctctac tgcattttta gacattgtaa
     7201 tttccattcc tactccccct cttcagttgt tgtcttctat tatttaacaa ctacatctgt
     7261 ttttggttga acttttgcat attttggata tttagggaat ttagctacac aacggaaagc
     7321 cgtcatccct gcatattttt cgtaatattt cttcgttggc ccttcaaaat ccttgctcca
     7381 cggtttcaca tgtcctgaaa aatggataat gtaaggattg ttgcgagttt cttcgtattc
     7441 acgttcacct gctgctgttg gatgtttttt tgcttttgcc atgatatagc cttgtgcatt
     7501 ccaacgcgga tgaagtggta accaacggtc atgtaagata gcatttaatg catcttggtc
     7561 atggaatcgt aatttttctg gattatgttc gatgaaatct aatacttttt gcgtaatatt
     7621 ttcatctaac cattttttca cattgatcag catcaaacct gagttgaaat aacgcattga
     7681 tttagctgaa attttcattt tttccagtcg ttgatggaac ccagcgtctt caacagctgc
     7741 tacgattgaa tcaccgaagt caagacgcca taatttagag atatcttgta aagcgatcat
     7801 gtcgcaatcc atatataaga tacgttcaac ttctgtgccg cggaacaatt ccggaatcgc
     7861 aatacgataa taagctgttt ctggaatacg atcgctgatt accacatttg taaagaattc
     7921 tttattgatt ttcaagaatt ccacatctga gttcattcgt gcgtttttca ctgagaagcg
     7981 taaaagctgt ttactttcaa aatcgatatc atcgtcaatc acatagaacc gaacaaattt
     8041 agacgggttg caattatcta atactgagac aaataatgca gctaaatgtg gtacgaattt
     8101 tgtgttacaa cttgcgacta ctgctatttc ttttttattc attgatctcg cctactttcg
     8161 ttagagtact gtgtgctaat ttttttaagt ataaattggt atacggatga tctttcaacg
     8221 tattccaagg tttatcatgt cctgtaaagt gaacgatcga aggtttttca tttccttctt
     8281 tatactgacg ttcatatttt tcatttggtg ctggatgacg ttcaaaaatc agcgaagtct
     8341 gcatgttcca ttttggatga agttgttccc aatcttcata aagtacagca ttcaaagcat
     8401 cttggtcgtg atagatgatt cgatcgccat tttcactgag gtaatggata gttttttctg
     8461 taatttcttt tttattccat tgatcaatgt caatcaccat cactcctgaa ttgaagtaca
     8521 agtcatcgga atcgattcct aatctttcca aagctttcac ttggcctgga tcgataatag
     8581 cgccgattgt ttttccattt aacggctcat catatagttt tacgatatcg tctagtacta
     8641 acacatctga atctaagtaa aggactttct tataatcctc tttagctaat aagtttggta
     8701 aagaaattct taagtaagcg gtagttgtga tatggtcact gactaggaag tcttcgtaga
     8761 tatctttttc cactgtcagg aattggatac ttgcattact tgaatattta tttaccgttt
     8821 cttccaatcc ttctttacta tattctgata gaccatcgtc aatcacataa aattttatgc
     8881 gtcttgtttt attgcaattt tctaatgcag ttgcgatcat cacgctcaag taaggagcat
     8941 aattttcgtc tgaagcagtt accacaggaa ctacgccgta tctcttctcc atcaaaatca
     9001 ctcctttttc taatcttttt ctaacctgtt ctacatctag aatattcctc atttggtttt
     9061 aaagcaaaat atatgctttg ttttcattga atattttaaa atttttttat cacaaaacgc
     9121 atcggtaagc gctaactatt cgtttttcat ggctttttat tcaaaggtat tgaccaaaaa
     9181 ctactatata tagccacctt tttcttaaga atgttttttg aaaaaattca taatgacaaa
     9241 gcaagttagt ttcatttttt taaattctca tttaatctta aggtaacagg aaaatagata
     9301 tgtaaaaaga aagtaggaag ataaaatgaa actagcagcg attgatttag acggtacctt
     9361 gcttgatcga aatggaaaga taccagaaga aaatatccaa gcacttcgga aatttgatga
     9421 aaatggcgga atcgtaaccg tcgctaccgg aaggaacagc atttctgcta aagatatttt
     9481 ttccgaatta ggaatcggtg gctatttgat ttcttccaat ggttcactga ttgctgaaat
     9541 gaaggatgga aaaatggcga aagttctcag acgttcaaaa atagatagcg atacactgag
     9601 aaaagccttc ttctatgctc aagaagcgaa aatatccatc attgctagcc gagaaaccca
     9661 agatgatcag ctgacattcg atgaatcaaa tctagtcaaa gatgaccctt attatgaaca
     9721 tttcaattta cagaaccatt cttttgatca aattttaaat atgttggaag atccttctct
     9781 tagctatctt aaattagcat taacagataa gagtgaagaa aaactacaga agctacaaag
     9841 agatctgcaa gcagatggta tccaatcagt attctctgat ccgcatttct tagaaatcac
     9901 gcctacaggt atcactaaag ctcattcact tgtttttctg gcggattacc ttggaatcga
     9961 atcgagtgac atcatggctt ttggcgatca agaaaacgac attgctatgt tgaattacag
    10021 cgggttgagt attgcgatgg ggaatgcaca gcgacaagta aaagaaattg caaaccaagt
    10081 aacactgacg aatgaagaag ctggtgttgc ttatatttta aaaaacttct attaaaaaga
    10141 ataaaatgac gatatgaatg taggaggaaa gaaaatgtta gttattattg atatgcaaaa
    10201 tcatattctt gatccaaaca gcgaatttta tattccagag tcagatcaat tggcagaacg
    10261 tattgctcaa agattagcta aagcacgcca aaataatgaa tatattctct tcacacggga
    10321 tataccagtt gaactgaagg acaaagaaga agaacgagaa gatttgcaat tgatccctct
    10381 tctttctcca caagaaaatg aacgagtgat taaaaagtat tactttacga ttccacctga
    10441 aactttagct gaaatccagg aaactttatt tgaaagcaaa gaagaacaaa aagagatcga
    10501 agtagtcggg attgaaacaa acttgtgtgt actctctaat ctgataggcc tgcagagtgc
    10561 ttttcctgaa gcagactttt ttgttgatcc aatgttagtc tccagtagaa aacacggaga
    10621 atccgcttta gagctgttga aagatttcaa cgtctctatc gtcgaatcat aaaaatatct
    10681 atcttcattt acgatattta acacacaata aaaaaagcac gcagaactgt tttagtccta
    10741 cgtgcttttt ctatcaaagt agattggctt ttttatgaca cagagtgaaa cggcaggctc
    10801 acgacctctt tcttaaatgg tgttcaatca gctgaccctc ggtattagct taacaaacgg
    10861 caaaatatga ggaactattt ttccgtttgt taagctaata ctcaggtcaa aacgctgatt
    10921 tcacaacctc ttccttaaac ggtattcaaa agcttgcatc tgcagtaata agaacagcca
    10981 agtaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg cagggcagct
    11041 ttttcacaac ctcttatgta ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
    11101 gtctgctcta accaactgag ctaaaggtac atcataaata aaatttattt ttgttacttt
    11161 tcaactatag cacgaatgac aaactctcac aagtttcaaa atataagtaa aataatattg
    11221 ttattcttat ttcttttact tgtgtcataa ctattttgtt actttaattt ttatttgctt
    11281 attttagaaa aaatgttatt cttttattta ttctcaatgt taggagtgat tattttgcca
    11341 tttattgcga ttttattcga tttagttgcg gcagcagctt attttctcca attaaattat
    11401 caaacctcag gaattctgtt tattggaatg atttttcaag gtgtgattac ccttttgctt
    11461 cttgtcatga tgctcagcta taaaggaaaa agatatgccc gtattcaaac aaaagtattt
    11521 gttaaatatg tttccattcg ctatgggatc atcattcttt cctttttagt gaatgcgatc
    11581 gtcctctttt tatatgtatt gaattactta gatatcaatc cattgatttt ttctcgatag
    11641 ataagacaca ttcagcggaa cagttcctgc ttatcagcag aaaactgttc tgctttttca
    11701 tttttcattg atctattctt cttttatttt cctagcattt catttgtgat gtatgcaata
    11761 acatgttatc ttttattata tgaatcgttg aggagtccgt tacatgatta cgttggtgag
    11821 agttttgttt tgggtgcctg cggtcgcact ggtcgcaagt attgtttatc ttatgaattg
    11881 gaacaaagaa cggttttatt tagctatttt gactcttccg gctatctact ttatgtggaa
    11941 agtttttaat tacaactact ttgaacccga tagtgttttt atagaagaat tatcaggact
    12001 ggttttgtct ttattgatcg tcattcttta tttgatacgt ttaaataaaa aacattgagt
    12061 actattgatt gcatgtgtag ctttctatag tcattataac tattctacta taatgaaagg
    12121 tgattaaatg agtatcgaag aagctatttt actggatact ttacgttgtc gtctgaattt
    12181 cttaagaact ggccgatctt tatctcaagt agctgtttct agcgcgttaa gtattccttt
    12241 attcaaatat cgtaagtacg aagaaggaga agaaattcca agcatcattg aattaatcta
    12301 tatcgctgac ttttacgata tttccgttga ttacctaatt ggtcgctcag aaacagcaag
    12361 caaactgaag tgattttttc cagccttggt gctggttttt tcatttaacg tctaaggtta
    12421 acaatctata tataaaggag acatttctat gcgattatgg catgaaaaat tgatttcaaa
    12481 gcttcctcgt caacagcttt taggacaaca tcgggaatgc tgtgcattaa gaggaaatgg
    12541 ctggggaaag aaacatgcta ctgtggatta tgtttttcac tattctcctt atagattatt
    12601 ccaatatcat cagcttgtca tggatgaaat ggaaaaacgt ggttacagcc cagcaccaga
    12661 gtggaaaaat cctatgtatc gtggcaaatc atgcgaagca ttttttgatt tacctactgt
    12721 agagcgcaac gtgccgattt atccggaaca cgatgaagtt tatctagcag aatgtttagc
    12781 aaatttggag caaaaaggaa tttatcttac ctaatataac tagaaaagcc ttctatctcc
    12841 tcttacttca ttaaaaagct ttaaccatct tagatcaagc taaaatgtcg taagttttag
    12901 ggttatcttc atcctcacgt gcaaaactaa aagcgtactc tagttttggt tcatcgccaa
    12961 cttccctaga cataaatgaa catctcctga cgtggtttaa aagtaccgca tcttcgacgt
    13021 ctgtatacga tgcacagcac agattgcttc ttttgatctt tcttttgatt tttctgttgc
    13081 ttcttctaca ccttcttcga ttactacatc gatgcttaca attgcttctg cctaatattc
    13141 ccatgcatcg tcgatttaag cctctgtagt cactgtgatc gtttccacat tttaactcct
    13201 ctgtcgtggc ttcagttgat tttgtgatca gttcagttgc taagccagag tcagaacaac
    13261 ctgccattgc tagcgttaat attgatagta aaaatagttt ttttatcata aggttccccc
    13321 cctgaaaata gactaaaata ataacgcttt ctttttttgt tttcagacga aaattaataa
    13381 tttctaaata ttctttaaaa aagcttataa ctattatgcc ttttttaata tataacacag
    13441 ttatttttaa aaataagaat gctaaatcac tctacaataa cggcgaaagc acaaaaaata
    13501 aaaaaattat tacgttatta aaaaaacaga tgaaagatca ggttttatta gatctcattc
    13561 tttcatcact tgaagggatt taatgaacta ctttttcctc tttgtcgttt ttatatattc
    13621 gtattccttc aaacagtagg atagcctctt tcaatgcttg atatttgaac tgtccgttac
    13681 ttaaaaattt agatgtgccg ccctcttcct agaacatatt cttttttact ttttcattaa
    13741 ttgacagacc aatcgaacga aactgtaaat ttcgatagga taatgattgg tcaaactcat
    13801 tcattttcaa gacatctcga ttcatattca agataggaat ctttttatca acatcacttt
    13861 attcgtattt tcctctacca taaaagcttc acgctccaca aaattgtttt atacactact
    13921 attcagccca ttcaacgacc aatgaatttt
//
LOCUS       DAPBBV010000060        13854 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.060, whole genome shotgun sequence.
ACCESSION   DAPBBV010000060 DAPBBV010000000
VERSION     DAPBBV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.060"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..138)
                     /locus_tag="RD486_002442"
     CDS             complement(<1..138)
                     /locus_tag="RD486_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HDT7664155.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
     gene            complement(369..1499)
                     /locus_tag="RD486_002443"
     CDS             complement(369..1499)
                     /locus_tag="RD486_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7664156.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(2040..2246)
                     /locus_tag="RD486_002444"
     CDS             complement(2040..2246)
                     /locus_tag="RD486_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664157.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2262..2876)
                     /locus_tag="RD486_002445"
     CDS             complement(2262..2876)
                     /locus_tag="RD486_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDT7664158.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(3023..3706)
                     /locus_tag="RD486_002446"
     CDS             complement(3023..3706)
                     /locus_tag="RD486_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDT7664159.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3815..4273)
                     /locus_tag="RD486_002447"
     CDS             complement(3815..4273)
                     /locus_tag="RD486_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDT7664160.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4357..6120)
                     /locus_tag="RD486_002448"
     CDS             complement(4357..6120)
                     /locus_tag="RD486_002448"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDT7664161.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6341..7801)
                     /locus_tag="RD486_002449"
     CDS             complement(6341..7801)
                     /locus_tag="RD486_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664162.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELLDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(8009..8935)
                     /gene="glsA"
                     /locus_tag="RD486_002450"
     CDS             complement(8009..8935)
                     /gene="glsA"
                     /locus_tag="RD486_002450"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDT7664163.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8958..10385)
                     /locus_tag="RD486_002451"
     CDS             complement(8958..10385)
                     /locus_tag="RD486_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7664164.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10416..11630)
                     /locus_tag="RD486_002452"
     CDS             complement(10416..11630)
                     /locus_tag="RD486_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HDT7664165.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(11971..12213)
                     /locus_tag="RD486_002453"
     CDS             complement(11971..12213)
                     /locus_tag="RD486_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7664166.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(12245..12802)
                     /locus_tag="RD486_002454"
     CDS             complement(12245..12802)
                     /locus_tag="RD486_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7664167.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(12815..13003)
                     /locus_tag="RD486_002455"
     CDS             complement(12815..13003)
                     /locus_tag="RD486_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDT7664168.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(13016..13582)
                     /gene="amaP"
                     /locus_tag="RD486_002456"
     CDS             complement(13016..13582)
                     /gene="amaP"
                     /locus_tag="RD486_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDT7664169.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4138 a         2847 c         2262 g         4607 t
ORIGIN      
        1 cttcagttga tcagtatttc ttcggttttt aatcttatct ggtacacaat tgtggtatat
       61 gttagaaaca gttctcataa tttccttgaa tgttataaaa gtatctgtat aatgttcagt
      121 atattttgat gaacgcatat gtagtcctca tttcttggga gttttgagac tactatatgc
      181 gtttttttgt tgatttacca acatgtttag acattttcct ctaggaaaaa attaactagc
      241 accacgggta taatatgatt ttttgagata ctttcattgc gaattcctct ttctaaaaga
      301 acctctcgct tgaaaaataa aagattgtac tttatgataa ttcaaactga gagtttctca
      361 gtttctcttt attgtttttc aggtcgatag agcgccaact cttcggcctg tatctttgaa
      421 gaaatattca acgtgattcc gattcctaaa gaaaggatca gataacttgt tcctccgtag
      481 ctaacaaatg gcaatggcac accagtcatt ggcatcagcc ccgcgatact tcccacgttc
      541 attatcgtct gaacgaatag caaagttccg aatcctaaaa gaaacaatcc agcttgctga
      601 tttttacagc gactgcttaa acaaaagatt ctcatgcata atgagaacaa taagaaaagc
      661 acacacaatg caccgattag cccaagctct tctgtaataa tcgaaaaaat aaaatctgtt
      721 tctgtctctg gaagataccc tttttttgtg atactatttc ctaatccccg cccaaatatg
      781 ccaccattat atagtgcata aaacgaatgg gtcatttgat agcccgcacc atgactatcg
      841 ataaaagaat ctcttaaagt cgcgatcctt tcataagcat gattaaacat ctgtggaagc
      901 caacctttat ttcctaaata taataccccg cctgctgctc caatcagcaa tgcagaaaaa
      961 gtaacgatta gatagatccc ttttttaaat ggaaccgccg ctgcccaaaa tatgacccac
     1021 gcaatcgaaa ggatcatcaa tgctccagca atctttggct gaaataaaat cagaaaagtt
     1081 atacctactg taatcaggaa tggttttttt agatcttttg ggctactatt tccgtcacga
     1141 aaaaaccagc ttaaataaaa aatcaaaaaa agatttgcca gttcagaagg ctggaattga
     1201 atgccaaaca gagagatcca acgttgtgcg ccgttgacag tgacaccgaa tatccctatt
     1261 cttactaata ctaaaaagaa aatcgataag gctaaaccgt atcctgctat tttagggtga
     1321 agtaaatagt gtagtttgac tgaacgagct aagaagatca cgctccaact caaaaatatg
     1381 aaaattagtt gacgcaataa tagacttttt gtattttcat cggcttgcaa taaacgataa
     1441 gaactggcac tgtatacttc taaaagaccg atcatggaca aagtcaaata aggacccaaa
     1501 atccaccaat cgatcttttt tcaccgcatc tcctcctcac acagcaatcc acttgtcagg
     1561 tgaggagcga gtttgtctca tcaaataagt cagtcacaaa aatataaaga aaaggtcaga
     1621 aaccttttcg aacaagaatt ctgacctagc atcatctcat cgtccgagtt ttagcactat
     1681 acaacgtaaa gaaaacattc ttagctattg gaaaaagcct taatccaaca gtttctgttt
     1741 tacccattgg cgactttcga cgtttctggg caacagccta tgtttgtata ggagcctcac
     1801 ctaacaaggt tattactata ttctatttac gagttcatga tagacttttc ctaatgatta
     1861 ggcaatggaa tttgaaatga aatagtgaaa tttaacaatc tttaatattt tttagaaaaa
     1921 aataacaaat aagttgaaag aatcccgttg caaattcttt cagttgcacc aggattcttt
     1981 gataattttt tagttttatg tgttttttta tatgtttttt cacttttcgg aataaatatt
     2041 tatttgttaa agtaattaaa caatccgcta atcgtttgat ctggcatttc tatttcctta
     2101 ccatctaaag taacagtagt aacgacaaaa tggtcttgca atggcggaac ttctaagtac
     2161 tgcccttgca gaaaatcatt cactgtttca tattcttttt tcatttcttt tgaatctgtc
     2221 gatggtttat agcttatttt taacataact agtgctcctt tttattcggg acgtgcaatc
     2281 gtgaaaattt ctcctattgc tgcataatca tttcctgcca aacggcttac agcattcaat
     2341 tttcttggat cgatccttcc tgtcttatca tcatagactg tttcatttaa atgatatttc
     2401 tgtacttcta gcaaaaataa atcagctgtt actttatttt tattccgtat ctcgacatgt
     2461 tcatataagg atgtttcaaa acgaactttt gcttctgtca atgctggtac tgaaatgatt
     2521 actgaatcag ttaaagtcaa gtcagtcagg tacagttcgc tttcctcatt aggcagattg
     2581 gctgctgttt tatttacttc ttctacgttg tcctcatcaa ggatatggat aacagcttct
     2641 cttgtctcaa gaatattctt tgctgtgtct tttactgcat cttgttttct ctggatcgcc
     2701 aaggataaga tgggtcgatt cgaactgacg atattgaagt aactgaaggg tgcgatattc
     2761 actatatctt ttgctgattt agtcgttact actgctactg gtctagggat gactgaacca
     2821 atcagcaact tgtaattttc acgttctgtc aattctgaag gactccgttc aaacatggtt
     2881 tcgccttctt tctataaaat tcgttaaaaa gcagatcttg aagacaaaat gaaaagtaat
     2941 gcttttttca tcttcttaga atctgcttta aactatctat caatttttct tttttgtcaa
     3001 gaatctgtgc cgtgcgtgtt ttttagttat ttgctttact tgcggcttcg acatatcttt
     3061 tagtgatcaa ttgcggacgg gtgataatag atccaactac gactgaaaaa gcacctaatt
     3121 catatgcttt ctctacttgt tcaggagagt cagtatgtcc ttccataatt actgggatat
     3181 cgacttgttc tatgatttga ttcaataaat caaaatcagg tgtctgcgtc tttcgtgaat
     3241 attctgtata gcctgctaaa gtcgtagaca aaagatcaaa accatcttct tgcgcttgaa
     3301 gcgcttcctc aaaagtcgaa atatctgcca tagctaaccg accgtgttcg tgaatcattt
     3361 ggacaagttc agcagttgtt ttttctgtcg gacgtttacg agaagttgca tccagtgcaa
     3421 tgatttctgc ttgcgtctcc aaaagttctt ccacttcttt ttctgtcgca gtaataaaca
     3481 cttctgaccc atcgtaatct cttttgataa tccctattac cggtaaatca acgattcgct
     3541 tgatttcatt gatatcttct gtcgtatttg ctcgaatacc aactgctccg ccttcttttg
     3601 cagccaaagc cattctcccc ataataaaag aactgtgtag cggctcgttt tccaaagctt
     3661 gacaagaaac gacgactccg cctttgattt gttccagtgt atccacaata tctcctccag
     3721 taatgttata taaaaataca gcttcatata aaaatgtaac ccttttctat tcaggagaca
     3781 ataatgagct atttctttca gcagaccttt cttactaaaa gaaaattact tcaaattctt
     3841 cgtatacgac cagcttctct tctgtaaatt ctatgttcaa cgcttcttta taagcatgtt
     3901 taaaaaactc agcatggact ttccgccaat aagctaatgt ccgatcccct tctccttctt
     3961 tccaagcatg ctctttcgtg acttcactaa aaggcaagat ggtcacattt atatttttga
     4021 tgatacaaac tggttcattt tttccattca ggaccacgtc taattgacca acttttggta
     4081 aaggctcatt ctcttgttta tacagatcgt aaccacttga tgtaccagtc tttatctttt
     4141 ttacaactag ttcgctcaac tcgtctgcca ttttttctgt atccccaaat gaaaagaaac
     4201 ctaatttttc tgattgataa ctaggatatt tttcttggaa ctttttgaca tattcttcta
     4261 cttgctgata cataacatcc acccctttgc tttttataat gaaaaaacca tccagatact
     4321 agtataaaca attatctgga tggtgagcat aatgaattat tgaatattca agacacgcag
     4381 actatcttca acgatttgtt ttggtgttaa atgataacgt tcataaagct gccctacagg
     4441 aacgctatcc gtgaattctt tctctgcacc aaaatttaat acgttcattg aagaatcacc
     4501 ataataacga ctgatatttt cgccaaatcc tcctgacaaa ctaccatctt ctaatgtgat
     4561 gactaattcg tgtgtttctt ttaatttatc taatgtttct acgtcatttt ctgtgatcgt
     4621 tcctggattg atcaacgttg cttcgattcc tttttttcta aaagctttta ctgtttcttt
     4681 tcctaattca agaaaaccgc ctaaagctaa aattgctact tttcctccat tatttactgt
     4741 ttgataggct ggaatactat aatcatttgc gatagctgta ccatgttcta caccatgtgt
     4801 aggaattcgg attgctacag gctgcgctgt ttgttcgaac gcccaatcta gcatagagat
     4861 catatcctct tttgttgctg gagcaagata tttgatgttc gggatacttg ataagtaagg
     4921 aatgtcaaat gttccttggt gtgttcggtc actagctgag atcgttccgc caccgactaa
     4981 aataatcact ggattctcgt tgatcgctaa atcatgtgat aattgatcat atgcccgttg
     5041 caagaaagta cttgattgga agacgactgg acgtactccc tgagaagcca aagcagaagc
     5101 gaaagtgata gagtgctgtt cagcgatccc cacgtcaaaa taatgatctg gatgtttttc
     5161 ttggaatgtt ttcagtccaa aggcgcctgg tatcgctgca ttgactgcgg caataggagc
     5221 tgtacttgtt tgcattttct tatccaaata atccatgatg atcatattaa atgtttctcc
     5281 agaagttact tgctttgcct ccccggtgga cagatcaaat ggtacatgcc aatgatattt
     5341 cattttatta tcgattgccg gctgataacc gcgacctttt tccgtatgga cgtgaagtac
     5401 aatcggatga tcaatatctt ttacttcttc aaataaacgg atcaccgttt ccagatcgtt
     5461 tccattatcc acgtaacgat aatcaaatcc cattgcttta aataggttat tgctgctttt
     5521 accgttggtt tgacgaagct cagctaagtt tttatataaa ctgccatgat tctcatcaat
     5581 agacatctca ttatcgttta ctaatacgat tagattggat tgtaaaacac caccattgtt
     5641 caatccttca aaagctaagc caccacttag ggagccgtca ccgataaatg ctaccacatt
     5701 tcctgattct ttcttcagat ctctcgcttt agctaaacct gttgctaagc tgatagatgt
     5761 agatgtgtgc cccactgtaa aatagtcatg tttactttca tgttggttgg aatatccgct
     5821 cacttcacgg taatgtcctt tttcaaaacc attttttcga ccagttaaaa gcttatgacc
     5881 ataagactga tgggaaacat cccaaacgat tttatccttt ggtgaatcaa atacataatg
     5941 aaacgcaatc gttaattcta ctacacctag attcggacca acgtgcccac ctacatcgct
     6001 gtccttttgc aagatttttt ggcgcatctc ttctgccaac tgtttcattt cctcaacaga
     6061 taattttttg acatctgcgg ggctattgat tgcatccaat acatgtaata ctgtactcat
     6121 aatacattct ctcctccgta ctatcttctt ttaatgaaaa tagatttgtt acactttatc
     6181 tattctacta cttagagttg actctaagtc aatagcattt taaaaaaatt tcagagaaag
     6241 cttgttatat aagtagatct tcgcacgaat caggactcaa ataaaaacct tctacagaca
     6301 attaaaaagc tttgtagaag gtctcctaat taaggtctca tcaagaaata tgttttttta
     6361 ataggtgaag ttcctgagca atatgataca aatggatgtt tgcacctttt aatgagattg
     6421 gatagatctt tgtcttttca gtttctaatc cattttgata gctagcagca tcgcacaaaa
     6481 ccactctttt tttcgcacat agacattcat caagcaattc ttctaatgaa cgaaataaaa
     6541 taggatttat ttcagcgatg ccttcttccg catacaaatg aaattgggtt cgataaaaaa
     6601 attgtttgac tgaactttct gaaacaacaa aaatttctat ttcctgtctc cccgcttgtt
     6661 cactgttgat caaagaaaga cttttgacga attttcgaat gaaattttca ttccatctta
     6721 gttggatttg atttttcttt ttccactctt ccaatatttc tacaattttt ccgtacagaa
     6781 gttgttcttt ttctgataga agatagatcc tttccggtaa aaatacttgt ccatctgccc
     6841 acaacgtacg gacaaattgt aaaaaggatt gcttgaaaat aaaattttct gcatcgtcga
     6901 tttcagcgat actaataatc tgtaaaatca attcattcag tgataggtca ttgagaacaa
     6961 aatttttata aacaacttcg aaatcttttc ttaacagctc catgttctca ttggtataat
     7021 ttctactgtt gaacaaagaa aaaatataat agacatcttc ttcttgtaag tctagaattc
     7081 ctttttgctc ttccaatcct tgacagacta attgaaataa cggcttcgtt tctgcgcttt
     7141 tcttatcttc ttctttcagt ccaaggggaa atgcctttct tccgattgcg atctctattc
     7201 ctcgtatgat aaaggacttt tcatcttccg aatatcttct tttaaaaaaa tgagtctcta
     7261 cataatcaat caactcgtta caagcttctt ctacatacgg atttttattt tcatagcctt
     7321 cccaattgac ataacgtact aaagctagca agatgttccg cgagtcaaat tctgggataa
     7381 tgatttcttt atttttcaaa taatcatttt ctttaaaaaa atccaatacg atttttttga
     7441 ttgtatatac tttgctcaaa gaaataaatt caagatcagc cagttctgta ctcgtgaata
     7501 taccattaaa ataataactt aaaaacttta aaaaataaga ttgaccgtac agaaactgtg
     7561 tgagctcaga aagagcaata ccatgtttga atacgagttt atacttatgc ttctctctta
     7621 cttgttcttt tatacaatat tctagacact cggctagact ttctagatcg tgaaggatcg
     7681 ttggtgtagt cacccttaga gaaatagctg tttgttcgat gtctatttct tggaattcaa
     7741 ataattgttc acacagatac acttttctaa atatatttcg ctcgatgtaa ttttccagca
     7801 ttcctgatac acgcctccag tttttcttat gattttattt aatcatatct gtaaatcgta
     7861 tttttgtttc ctttttattt agaaaagccc tttcaaaaac caataaaaaa agaaactggg
     7921 acaaaagtca aacaagctca caatttcagc ctcattgtag gtagctttga gccgtttgga
     7981 cttttacccc agcctctttc aagaatggtt attcaaagat gtcagcgtct agttctttga
     8041 ctacatcttt caacaattgg ataccagctg cgctgttacc aaatggatct agtgccgggc
     8101 tgaagacacc tatgccgtaa cgatttggca cagctgccat caacccgccg cctacaccgc
     8161 tttttgcagg tacaccaaca tggacggaaa actctcctga ttcatcatac aaaccagcag
     8221 ttgtcataat tgatttgacg attgtagcac tttcttcagt aatgatttgt ttgccattcc
     8281 aaggagcaat tcctttattt gccagcacag cagctaattt tgctatgcct gtagcggtga
     8341 cattgaggga gcattgtctg aaataagcat cgagtatctc cggtacgtct ccttcgatca
     8401 tttgattacc tttcatatag taagcaagag agcgattgat atcacctgtt cttgattcag
     8461 aatgatagat ttcttcattc aatgtgatat taggatcatc acagatctct ttcataaatg
     8521 acaagattcg ctcaaatttt tcatctgcat ctttaccggc aatcaacgag gttgttgcaa
     8581 tcgctcctgc attaacaaaa ggattcattg gatgtttgcg atgattgatt tccatattca
     8641 tgatagaatt gaaggcaaaa ccggttggtt ccgtgttgat tgtttgaaag actttttcta
     8701 ttccgttgtc tttgattgct aataacaata cgggaacttt tgacatgctt tcgatggcaa
     8761 agcgcacatc ggcgtctcct ccctcaatca gttgttttgt atccaaatca taaatcgcca
     8821 tacctaattg tttgggatcc acttcagcta atgctggaat gtaatccgcc acttgtcctg
     8881 tttgataata gtggaaattt tttccaatca attgttctaa ttcttttact tccatttgaa
     8941 taaccagctt tcatttttta tttttctgca tgctggaatt tatgacggca tgcgtagatc
     9001 gtaaatggaa taactaagac gataagataa gaaacaatca gaatcgtttc ataaatccca
     9061 tgctgtccag ctgcgatact agcaggtgga acaaatgaga tacaaaaagc aaaaagtgaa
     9121 gtcaaaagac ctaaacaagc aacgattact tttacaactt ttccgcctgg aacctgatag
     9181 gctctttcaa gactgtcatc tttaaaaacc agcttcaaat agcccgcgaa aaacataaag
     9241 tacaacatca ggtagattac aacagtcaat gacatcgctg caagaaatga aagattattc
     9301 cccccgccgc ttaatgtaaa gacggctgcc cagattgttg caacgatccc atttgcgatc
     9361 atcaaatgag caggaacacc gtgtgtgttt tcttttgcaa aatattcagg aagtaatcct
     9421 tcttctgctg ctacgtgaag tgcttttgaa ggagaggtta cccaagaagc aatttctccg
     9481 atgacaccta aacaaacaag aatcgcaaga attttcgcaa tccatgcaag atttggatca
     9541 atgtgtctta ataggaattc taacgattga atcacccctg tattaagaga caaaccatgt
     9601 tgaggtactg tagtagcgac ggtcaatccg ccaaaagtat ctaaaatgat tgccagaata
     9661 accaatacaa acattgctaa tggataatcc tttttagggt tttccatttc atttgcatga
     9721 ctggcagatg tttctacgcc catatatgct aaaataaagg aaacaaaaac aaccagcgta
     9781 ggcaatttcg aaaaatcagg aatcaatgtt ttcatagaca gtatcgtttg tagtggagcg
     9841 cctgaagcga cataatggat ccctaagcca aacaagacta atgctggcaa caagatacca
     9901 gctacaaaac cgatccgagc aatcaatgaa gtgtatttgg ttccttttaa ctgtgagagt
     9961 aaaatagccc agaaaataat caataggatt gccaatttca gatatttatt gttttgtata
    10021 gcaccaatac ccgttgcata ggataatgca ccagttaaga aatacagcat ggtcaagtag
    10081 ccaactgtta tctcaaacca ttggaaaaag attgcggcaa aaccgaatcg ttttcccaat
    10141 gtgcgactga cccaagtata gacaccgcct ttttcccatc ctttcaccgt tgccatctct
    10201 gctgcgcaca atgccacagg gataaaccat agcaaaccgc ctaataacaa gaaaaatact
    10261 aagctgaagc ctgaggtcgc gaatgtggga tattcatata atgaaacgac cattgagatg
    10321 gtcatagcca aaaagccaaa gaacgttaat ttttttgcag gaattttcgt tttgctttgt
    10381 tgcatgaatc ttcctctttt ctatttgaat ttgtttcaat tgagtttgtt gccaaagaag
    10441 aaaaagtcca atccttcttc ttgttcttct tttgtagtag tgatcgttgt aaagtgcatc
    10501 gccgatttta aaatcactgt tgtcagcaca taggcataca cggcagtaat gatgacacca
    10561 atcacttgaa tccctaagaa gtaccagctg cttggattcg ttagtaaatg gctgttagat
    10621 gcaaagatcc ctatcagaat cgtacctgtg aatccgccca tgccatgaac accccacaca
    10681 tcaagtgcat catcccattg tttcttttta cgaaaatcaa cagcagcatg acagacgata
    10741 cccgcaatga tcccaatcag catggcactt tttgcttcta cataaccggc acaaggcgta
    10801 atggctgcca atccagcaac ggatcctgtt agtacgtcga caaaatcaaa gccatttcct
    10861 tttacttttg caatgatcag ccaagtaatc atcgcaaatg caagagcgat gaatgttgaa
    10921 ccaaatgcat tgactgcttg ttcatctgct cgaagtgcac caccggaatt aaaaccgaac
    10981 cagccaaacc aaagcagtcc tgtaccgata gcagctgcca taagactgct atgctgactt
    11041 ctttctccta aaggaatctt tctttgacca agtgtgagga tacatgctaa agagccgaat
    11101 ccagctgtcg tgtggatgac tgctccacca gcgaaatctc taaatcccat ctgatccaaa
    11161 aatccgccac cccatatcca gtggcaaaca gggaaataaa tcagcagatt ccaaaaaata
    11221 acaagtataa tatagccttt taaattcaat ctccctgcaa aagctcctgt catcaaagga
    11281 acggtaatca cgataaacat cagttggtaa agaaagaaca ttaaaaatgg aatcgttgca
    11341 ccatgaaaca tgttggggaa gcttgtaaca tgtctcatca aaaagaaatc tgccgggttt
    11401 ccaataacac cgccgatatc ccgtccaaag gccaatccga atccaccaaa tacccacata
    11461 atcgttgtta tcccaacgga gagaaaagat tgagacatga tcgttagtat attattcttc
    11521 cgtgctaatc cgccgtaaaa aaaagctaga ccaggagtca tcaggcaaac cattgctgta
    11581 cataaaatca tgaatgctgt atctcctgta ttgataggta atgtattcat ttttttcgcc
    11641 tcctttctac gattacgagt ataaaagaag gtgtagttgt ttttttcttc tgtttttttg
    11701 aattaatact tgcatttata aaagacagac aattaataaa agcttgatgt gttgtgctct
    11761 ttttcgtttt tcacacaaat aaagacaaaa aataaacggt cttcttttta tagaaaaccg
    11821 tttattttcg tcttttttta tttttaaaga tattttttca taaggaataa agaatacttc
    11881 atataaaata tataaaaaag aaccgcagcg agtgtcgcta cggttctcaa atttgttctt
    11941 catttcaaca taagtttttc ttcaatttgc ttataattta cgtgcaaaga atgaaacgac
    12001 taatactaaa atgattgcac cgatcaatga tggaatgata gccattcctg caattgttgg
    12061 tccccaagtt cctagtaaag cttgtccaat tgctgaacct actaaaccag caatgatgtt
    12121 tgcgatgatc cccattgatg atcctttatt cgtgattgct cctgcaattg ctccaatgat
    12181 accgccgacg attaatgccc aaataaatcc cattttaaat tcctcctaac tgacttctta
    12241 cttcttattg tacacgtggt tcgttatttt ctttgacttt ttgtgcacct ttgcctacag
    12301 cagattttgc tttatctgtt tggcgtgaag caaattgtcc tgtggatttt gctgcttctg
    12361 ttactttgtc ttgtactgtt tcttgatctt tttggtattc ttcttgtgtt ttgatgtctg
    12421 caacattcac attcacttcg ataacatcta aatgtgtcat attgtttact tcagtactga
    12481 tcaattcttt gatttggttg taaatatctt cgatgtcttt accgtattct acgatcacat
    12541 ctagatccac agctacttgt ttcttaccta cttctgtatt gatacctgct gttacgttat
    12601 ctgtgttgac taatttttca gccatatttg agaaaaatcc gccatctaat gtcaatagac
    12661 catctacatc tttcaatgca taaccgatga ttttttggat gactttgtct tcataagtca
    12721 attcaccatt catcatgcgg ttttctcctt tttcatttgc caaaactgat ccatttgttg
    12781 tattcatgtt tttgttttcc atctttgttt cctcctatga tttaaaaaat tgatcaacta
    12841 ttcctgactg tttcaaataa aaaccgattc ctgcgccaat tgctgtcatg attatgatca
    12901 acaatgtctt gaaaaatcca atcgttaacc ataaaacagc tagcagtagt ccaagacccc
    12961 caaagataat agggagcttg tatgctgaaa atagttcttt cattatttgg ccctcctatt
    13021 ccactcgaga gtgcttgtag tctcttgtat cttcttgttc ttcataaccg ctgtatgtga
    13081 ctgccacttt gaccgtttct tttgttccga gtactttagt tacttcttct tcgatatctt
    13141 gcatcaatac acctgttttc cctactaatg aagaagttcg tttcaagtct ccgttgacat
    13201 ggatatggat tcgatttttc gttgaacgta tccgtacttt aggtgaatga atgaactctt
    13261 cttcgtgtaa atgggaacgt accaaccctt cgatcgcttt tttgtcgatt gttagtttgc
    13321 catcttcccg tttcataacg aaagttcctc ttgactttgg atagaaaaga acgactagca
    13381 agatgataat agcaagaacg gcaaatacta cagctgccca gaaaatatat tgttgcatgt
    13441 agtaattcgt taaagtaaag aagcgaaatc gttccaattg ttcaggcata atatacggcg
    13501 cattgatcaa cgcaatcgct agaaatactg aaagtagcag taaactcatg ataacaccga
    13561 ttatttttaa ccccttattc attttccacc tcctataaac ttatttttac cctgtaaata
    13621 actctaccga caatcacagt atagatagcg aacagttagc atagcatcag taaataaagc
    13681 gctaccaaac attgctggat cataacggcg ttttattgcc agtctgatac tgaaataaca
    13741 attgcttact tattctctat ttacttttga ttgctggcta tacttaaagg atattattca
    13801 agattaaaaa ttgcaaagat tatgctcagt tattattaca agattctatt tatt
//
LOCUS       DAPBBV010000061        13721 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.062, whole genome shotgun sequence.
ACCESSION   DAPBBV010000061 DAPBBV010000000
VERSION     DAPBBV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.062"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..902)
                     /locus_tag="RD486_002457"
     CDS             complement(<1..902)
                     /locus_tag="RD486_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDT7664170.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(926..970)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1185..2153
                     /locus_tag="RD486_002458"
     CDS             1185..2153
                     /locus_tag="RD486_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7664171.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2266..2544
                     /locus_tag="RD486_002459"
     CDS             2266..2544
                     /locus_tag="RD486_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDT7664172.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2662..2898
                     /gene="secG"
                     /locus_tag="RD486_002460"
     CDS             2662..2898
                     /gene="secG"
                     /locus_tag="RD486_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDT7664173.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3001..3756
                     /locus_tag="RD486_002461"
     CDS             3001..3756
                     /locus_tag="RD486_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7664174.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3759..6116
                     /gene="rnr"
                     /locus_tag="RD486_002462"
     CDS             3759..6116
                     /gene="rnr"
                     /locus_tag="RD486_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDT7664175.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6138..6602
                     /gene="smpB"
                     /locus_tag="RD486_002463"
     CDS             6138..6602
                     /gene="smpB"
                     /locus_tag="RD486_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDT7664176.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6904..7623
                     /gene="atpB"
                     /locus_tag="RD486_002464"
     CDS             6904..7623
                     /gene="atpB"
                     /locus_tag="RD486_002464"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDT7664177.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7676..7891
                     /gene="atpE"
                     /locus_tag="RD486_002465"
     CDS             7676..7891
                     /gene="atpE"
                     /locus_tag="RD486_002465"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDT7664178.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7982..8506
                     /gene="atpF"
                     /locus_tag="RD486_002466"
     CDS             7982..8506
                     /gene="atpF"
                     /locus_tag="RD486_002466"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDT7664179.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8493..9035
                     /locus_tag="RD486_002467"
     CDS             8493..9035
                     /locus_tag="RD486_002467"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDT7664180.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9058..10614
                     /locus_tag="RD486_002468"
     CDS             9058..10614
                     /locus_tag="RD486_002468"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDT7664181.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            10628..11530
                     /locus_tag="RD486_002469"
     CDS             10628..11530
                     /locus_tag="RD486_002469"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDT7664182.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRAVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11553..12959
                     /gene="atpD"
                     /locus_tag="RD486_002470"
     CDS             11553..12959
                     /gene="atpD"
                     /locus_tag="RD486_002470"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDT7664183.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12973..13395
                     /locus_tag="RD486_002471"
     CDS             12973..13395
                     /locus_tag="RD486_002471"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDT7664184.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4535 a         2452 c         2991 g         3743 t
ORIGIN      
        1 ctttcggaaa aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc
       61 caaaattcat aacgatcaac caatgtttgt ccacgactta ttccctgagt ttccacagcg
      121 gtgaagcttt tgaaaccttc acagatggcc ccctcgatga aataagcaac agctaacgga
      181 tcattgatga cacatcctaa aattctttct tgtttccagt ggaagtcaaa ataaaaacga
      241 gtgatcgctt ttaaatactc tccctcttca ggattcattt gacagcagta ttcgaggata
      301 gtcggtgtca agacgatttc tcttgtcaca tctaacccaa ccatttctat cgtttgtttg
      361 agattctcga atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact
      421 ggcgaacagt taccatggct tttgtaagtt ccacccatcg agacaaaacg atccatatgt
      481 ttcccaatat ttgggttgac tttcaaagca aaagcgatat tggtcaaagg acccaaagca
      541 atgactgatg tatttgtctt ttctttgaaa taatcagcca aaaaatcaac ggcatggaga
      601 ggttctgcct gttttctcaa gatcatcggg aaatttgttt cccctaaacc atccatacca
      661 tgagtgtctt gtgcactgat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca
      721 ggaatgtcta aacgatcaca gcgttccagg catttcagca cattctgcgt acctatatct
      781 gcagggacat tcccacaaac tacggtaata gcaactactt cgatatcagg ggatttgaca
      841 gctaatgata aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tacttttcgc
      901 attatttcca atctcctttc tttagagata cttagttttt tattctggga agtttccgaa
      961 ccagtccaag acgagcgtct tgattataat gcacgaaatt agtatactgg cttttattgc
     1021 gaatgtaaat gctctcttac aagtaaatct attgaggaga actttaagta aatgatacaa
     1081 tgaaaaagaa atggaattta cgtgtgccga aaataaagaa tcctatggat cggtacattg
     1141 gataatagat agattatagt ttggcagaaa gcggcgggtg tacaatggtt attttttatt
     1201 tcattcttat tctgataatt atagggatca gttaccattt tctttcttat ttttatgcaa
     1261 agaaattagt aagagcggga gtacagagag gatatgactg gtatgaagac actggtcatc
     1321 gtttgatgga ccctgctgca gtcacgtcag tagaaaaaaa acgacaaaaa ttagaagaag
     1381 agtgtgaaag cttttgggag cagggaacac ccaaaacaat caaaagttat gacgggttga
     1441 aactagctgg tcagatgttc atccatccaa ataagcagaa taaatgggtc atttgcgtac
     1501 atgattaccg aagcacaggg aaaagagaca tgtctcatat aggtaaaaga tatgcagaga
     1561 aaggattcaa cgttcttgta cctgatttac gtgcgcacgg agaaagtgaa ggagaaatca
     1621 tcggaatggg atggctagat cggctagatt taattgcctg gatccaactc atcttagatg
     1681 aacagccgaa tgcgtccatt attttacacg gcggatcaat gggagcttct acgatcatga
     1741 tggcaagtgg tgaaaaactt ccatcagcgg tcaaaggatt tattttagac agcggatatg
     1801 tttctgttta tgcagaattc cgatatatgt taagtaaaat cactgtcttt cctaaaaaaa
     1861 tggtcatgag atatgcgaat cattatgccc agaaatacgc cggttactcc ttaaagcaag
     1921 catcagctac gagacagctt ggcagcaacc atctgccttt attagtcatc catggtgaaa
     1981 gagatcattt tgtccctaca gaagcagcgt acacgattca aaatgctacg gcaggggata
     2041 aagcactgct gcttgttcca gaagcagaac acttggaagc atcgatgaaa gatccgaaaa
     2101 cctattggac agtgattttt tcatttattg aacaaagaat aacgatggat taattttctc
     2161 ttcttttttg taagtaattc gaggataaat aattgtttat agatctggag actgctaaaa
     2221 taaggtagga ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagaa
     2281 gaaaaaaatc gtcttgcttt attcaatgat gagcaacaag agattggaga aatgacatgg
     2341 tcagatgcgg gcccagacat catgatcatt gaccatacat ttgtagatcc agcatatcgt
     2401 ggtcaaaagt tagctgaaaa gctagtgtat actggagtag aattagcaag acgagacggg
     2461 aaaaagatca ttcctttatg cccttatgca aaaaaagagt ttgaaaagaa accagaatat
     2521 caagacgtct tacgtcagtc ataagaataa cagctgaaag ttttgaactt tcagctgtta
     2581 ttccatttat atagagttgt cacggacttt tatctatgat aaagttaaag agacgatatc
     2641 ttttgggaag gaggctgcga tatgtataat ttaattttgg gaatcgtgat cgttttatcg
     2701 attgttatgg tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca
     2761 tttaccggcg gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc
     2821 atgcagcgat caactgcagt tatgggagct atctggatga tcttattatt tgtcctagca
     2881 tatttatctt cgaagtagtt gaataagcct ctcgcaaaac ggcgggcggc tttttttatt
     2941 gcaaagagaa cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag
     3001 gtgagacgag tgagacaatt accaaaaccc ctttatgcaa aacatggaaa gcgagcggtt
     3061 ttgctgcttc acgcttactc aggaagtcca aacgatgttc gaatgctcgc acgatttttg
     3121 gaaaaagcag attatacagt ttatgcgccg ctttttaaag gacacggaac aatggagcca
     3181 tatgatatct tgcaagaaaa agcagaaagc tggtgggcag acactaaaaa agccatccat
     3241 tttttacagt ctgagcagtt ttctgatatt gccgtattag gattatcaat gggcggcatc
     3301 tttgctgtac gagcactaga agaagaatca gtgattggcg gcggtttttt ctgttcgcct
     3361 ttgtctcctg taaaaacaaa cgtgcctgaa aactttgaaa aatacgtacg tcaagtgctg
     3421 aagacagcag gtaaatcaga gaaagaaatc aatgaaaaag cagttgctta ccgctcgtta
     3481 gctgaacaac aattaatgga tatacaagat caggcagcaa tcgtagaaag taggttgtca
     3541 gatatccaac agccgatatt tttagctcaa gctgggaaag atgaaatgat cgaccctaat
     3601 ggcgtatttg aaactgcacg caagttgagc cgtcagcgag tgacacttca atggtatcct
     3661 gaaagtggtc atgtgattac agttggtaca gcaagacgcg aattagaaaa agacgtcttg
     3721 gaatttttag aaaaattacc ttggaatgag gaataaatat gacaaaagaa acgataaaag
     3781 agaaaattct ctttttcatg gaaagcagtc gcaaacgcag tttttctatg gaagaaatcg
     3841 ctgaaggttt agggttccaa aaaagcgatg attttaaatt actagtacaa acgattgctc
     3901 aaatggaaag agaacagagt atagttttca ataaaaaagg aaaagtgaaa cttcctttaa
     3961 aaccaatctt gatcgaagga acatttcgag caaatgaacg aggatttgga tttgtaacga
     4021 ttgatcccga agaagatgac atctatatcc caaaagaagc gactggtttt gcaatggatg
     4081 gagacaccgt agcaatcgat atcatgaagc gagcaaatac agatatggat cgcggagcag
     4141 aggggaaagt agtcgagatt cgagaccggg cgactactca gttagcaggg gaattcgttg
     4201 cttattcaga agaagaaata caagaaacag atctttacgg cgttgttatc ccgaaagata
     4261 gaaagctcaa ccaatttaaa gtatatgcag cagcagaggg agttcgtcca gttgacggaa
     4321 gtattgtgct gatcgaactg acccattacc ctgaaaaagg gtatgcgact agtttagaag
     4381 ggataatcaa gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcaattg
     4441 tcgtggctaa tggtatccct acgaaatttc ctgatgatgt attgtctgaa gcagatgaag
     4501 ttccagatca aatcagcgaa aaggatataa ctggacgtag agatttaaga aatcagctca
     4561 ttgttacgat tgatggagaa gatgcaaaag atctagatga tgcagttacg gttaaaaaat
     4621 tagataacgg taattatttt cttggagtac acattgcaga tgtttcttac tatgtgacac
     4681 aaggcagtca attggacaga gaagcatatg aaagagggac aagtgtatat ttgactgatc
     4741 gagtgattcc gatgatcccg caacgtttat cgaatggtat ctgttcactg aatccccatg
     4801 ttccaaggct gaccatgagt tgcgaaatgg agattgatcc aaatggacaa gtagtctctc
     4861 atgatatttt cccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc
     4921 aaatcttaga agatcaagac gaagaaacga tgcaacgcta tgctcagctc gtacctatgt
     4981 tccaagaaat gggtgaattg catcgaatcc ttgaaacgat gcgaatcaaa cgtggcgcga
     5041 tttcttttga ggatcgcgaa gcgaaaatcc ttgttgatgc tgaaggacac ccaaatgaca
     5101 tccagctaag aagcagagga attggtgaac gcttgatcga atctttcatg cttgcggcca
     5161 atgaaacggt agctgaacat tataataaat taaatctgcc gtttatttac cgaatccatg
     5221 aacagccaaa agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc
     5281 tggtccgagg aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag
     5341 tagaagacaa accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag
     5401 cacgctattc agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact
     5461 ttacatctcc tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca
     5521 gtgaagataa aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag
     5581 atcatagttc taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga
     5641 agaaagcaga attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg
     5701 ttgtgaaatt cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca
     5761 atgaattgaa acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa
     5821 gaactggtct gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc
     5881 cagatgaacg agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac
     5941 gtccaaaagc acgcaatgga aaatctggaa aacgagaagg aaaacaagca ggcaaacgct
     6001 cagaaaaaaa tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga
     6061 aaaaagggaa aaagccattt tacaaagatg tcaaaaagaa gaaaaagaaa aaataaaatg
     6121 agttggagga aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag
     6181 ctcgccatga ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg
     6241 agatcaagtc gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca
     6301 acggggaagc tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta
     6361 atcatgatcc gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg
     6421 aaaacgaatt gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg
     6481 gctatgccaa ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag
     6541 atttgaaacg aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat
     6601 aatttcatta tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg
     6661 ttagcattta atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg
     6721 tgcatgggga aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga
     6781 aaatgttttg aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg
     6841 aaaaaaccag atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat
     6901 ggattggatg aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt
     6961 tgtataatgg tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga
     7021 aatcttaagt tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt
     7081 cgaggaatcg taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca
     7141 tttacattgt ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc
     7201 ttacctaacg aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact
     7261 ttggcattta taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa
     7321 ggatatttcg taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt
     7381 gaagaattta caaatttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg
     7441 gaagttttgc taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca
     7501 ttagcaattc cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa
     7561 gcatttgtct ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa
     7621 taatactcgg ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa
     7681 ttatatcgca gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg
     7741 tcaagttatc tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt
     7801 ccgtacaaca atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt
     7861 tatcgccttg attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat
     7921 cgtttgttac tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc
     7981 tatgctgaat caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt
     8041 tgtcagcggc tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat
     8101 cagcgatatt ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca
     8161 atctcgcatc aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg
     8221 ttctgatgca gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa
     8281 tattttgaag gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat
     8341 cactgtagaa cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct
     8401 tcaaatcgcg gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat
     8461 caatcaatac attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa
     8521 gacgttacgg gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct
     8581 atcaagatct cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt
     8641 taagtgatgt tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg
     8701 gttatgatgg gatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg
     8761 accttttgtt catgatcgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat
     8821 tgggaagtgt cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga
     8881 atgttgcaaa aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta
     8941 ttattggtgg cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc
     9001 aattagaaaa aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg
     9061 gccatcaaag cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac
     9121 gtgctttcag tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca
     9181 catggtttag aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga
     9241 atggcgcaaa acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc
     9301 attcgtgaag gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag
     9361 gccttgatcg gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc
     9421 gttactgaca aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct
     9481 gttaacgaac caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc
     9541 ggacaacgtg aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgatcgat
     9601 acgatcatca accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa
     9661 gattctacag ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca
     9721 atcgttgtga atgccggtgc gtctcaacca gcaccattgc tttatatcgc accatatgct
     9781 ggtactgcaa tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat
     9841 gatctttcaa aacaagctgt tgcttatcgt gaactttcct tgctacttcg ccgtccacca
     9901 ggtcgtgaag cttatcctgg ggatgttttc tacttgcact cacgtttatt agaacgtgca
     9961 gcaaaattaa gtgatgattt aggtggcggt tcaatgactg ccttaccatt tgttgaaaca
    10021 caagctggag atatctctgc ttatatccca acaaacgtta tttcgatcac tgatggacaa
    10081 atcttcttag aaagcgactt gttctacgca ggtactcgtc cagcggttga tgccggacta
    10141 tctgtatctc gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact
    10201 ttacgcctag acttagcaag ttaccgtgaa ttagaagcat ttacacaatt cggttctgac
    10261 ttggatgcag caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa
    10321 caaaaattgc atgcaccgct agctgttgaa aaacaagtag tgattttgta tgctttgaca
    10381 catggattct tagatagtat ccctgtagac agtattttag acttcgaaca tgaattattc
    10441 gaatatctgg ataccaatca ttcagatatc tttgaaacaa tccgtacaac aaaagatctt
    10501 ccagaagaag aagcgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca
    10561 aaaggaagta attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt
    10621 gagatgaatg ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac
    10681 gagccaaatc acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc
    10741 ttcttcacag aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac
    10801 tgctactcag ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag
    10861 catgctgctc agccgtgctg tgaagaaaac tggttatatc gtcatcactg cagatggcgg
    10921 tttagtcggt ggatataaca gctcgatatt gaaacaaacg atgtctattt tagaagaaga
    10981 ccaccaatca cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt
    11041 taaagcacgc ggtatcaatc tagcatatga gctgcgcaat ctatctgatc agccaagctt
    11101 tgatgaagtc cgcaaaatcg taaatatggc aacaactatg ttccaaaacg aagtattcga
    11161 tgaattatac gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga
    11221 aaaaatgctg ccaatctcag acttagatcc agaagaagca acgactttcg aacaagaata
    11281 tatttttgaa ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag
    11341 tttgatctac ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc
    11401 aatgaaaaca gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttataa
    11461 ccgtgcaaga caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc
    11521 actagaatag tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa
    11581 tcggtcccgt tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg
    11641 cattagttgt ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag
    11701 aattagggga cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag
    11761 gaatggaagt cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag
    11821 gtcgcgtatt caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg
    11881 cggaaagaag cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag
    11941 aaattttgga aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga
    12001 aagtcggact attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc
    12061 ataatatcgc ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc
    12121 gtgaaggtaa tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca
    12181 tggtgttcgg acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt
    12241 tgacgattgc ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca
    12301 acattttccg tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt
    12361 ctgcggttgg ttatcaacca acattggcaa cagaaatggg tcaattacaa gaacgtatca
    12421 catctacgaa aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact
    12481 acactgaccc ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac
    12541 gtaaattaac agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg
    12601 ctttagcacc tgaaatcgtg ggggaagaac attataaagt agcaacagaa gtccaacacg
    12661 tattgcaacg atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat
    12721 ccgatcaaga aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa
    12781 actttaacgt ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa
    12841 cagtgaaagg attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt
    12901 tccgaagtgt tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga
    12961 aaggggtgcc ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc
    13021 tatgatcacc atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg
    13081 cctaaacatg caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca
    13141 gattcagata cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat
    13201 aatgttgttt caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt
    13261 gcggaacgtg caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat
    13321 acgaacgaat tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta
    13381 tctaagcact cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag
    13441 gttatgacag aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca
    13501 aatttttgtg aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatca
    13561 gaggttgtaa aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct
    13621 catattttgc cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg
    13681 ggctctttgt caaatgatgt tggtaaagag aaatcttaga a
//
LOCUS       DAPBBV010000062        13149 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.064, whole genome shotgun sequence.
ACCESSION   DAPBBV010000062 DAPBBV010000000
VERSION     DAPBBV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.064"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(77..149)
                     /locus_tag="RD486_002472"
     tRNA            complement(77..149)
                     /locus_tag="RD486_002472"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="RD486_002473"
     CDS             530..1099
                     /locus_tag="RD486_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDT7664185.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="RD486_002474"
     CDS             1086..1946
                     /locus_tag="RD486_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7664186.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="RD486_002475"
     CDS             2136..2840
                     /locus_tag="RD486_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7664187.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="RD486_002476"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="RD486_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HDT7664188.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="RD486_002477"
     CDS             4677..5993
                     /locus_tag="RD486_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664189.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="RD486_002478"
     CDS             5994..6863
                     /locus_tag="RD486_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HDT7664190.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="RD486_002479"
     CDS             6918..7727
                     /locus_tag="RD486_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7664191.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="RD486_002480"
     CDS             complement(7830..8459)
                     /locus_tag="RD486_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDT7664192.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9923
                     /locus_tag="RD486_002481"
                     /pseudo
     CDS             8629..9923
                     /locus_tag="RD486_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(9999..10661)
                     /locus_tag="RD486_002482"
     CDS             complement(9999..10661)
                     /locus_tag="RD486_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7664193.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10886..11170
                     /gene="groES"
                     /locus_tag="RD486_002483"
     CDS             10886..11170
                     /gene="groES"
                     /locus_tag="RD486_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDT7664194.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11221..12846
                     /gene="groL"
                     /locus_tag="RD486_002484"
     CDS             11221..12846
                     /gene="groL"
                     /locus_tag="RD486_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDT7664195.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4371 a         2265 c         2833 g         3680 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatatg
     9061 cacgtttagt aagacttgcg aaagggtgga agcaaagaga gaagatacct gaaaatgttt
     9121 ggcagtcttt tacttcattg attccaatca ttgttatagt cacttttacg cttatcggtt
     9181 cagcggtttt tcaacagttg ttcagaatga ctgttgttca aggagtatgg acatatgtcc
     9241 agcttcccat tcaatcgttc atagacacgt tgtttggtgt gcttttatta ggtttttttg
     9301 ttccgttttt atggttattt ggtcttcatg gatctgcgat ggtcaatggg ttggttagtc
     9361 ccgtcttgca agcgaattca ttagcgaatg cagaaatctt agcctcagga caagagttga
     9421 cggtggcaaa tggcggacat atcgttactc agcaatttct cgatcagttc atgacggtta
     9481 cgggtgctgg attgacgtta ggggctgtat tttttatgac ggtttttgcg aaatcgaaga
     9541 aatacagaga attaggaaat cttgctcttt taccagcctt tttcaacatc aatgaatcaa
     9601 ttattttttc cacaccgatc gtgatgaacc cgatgatggc tgttcctttt attttcgcac
     9661 cggtcgtttc aggattgatt acctattccg ctttatattt tggattcgtt cctttattta
     9721 cagcagtcca agtcccttgg acaacaccgc cgatcctctc gggtttctta gtaggcggag
     9781 tgcctgcagc gattttacaa ggtatcgtgt tgtcaattag ttttttcatt tatttcccat
     9841 ttttgaaaaa aatagattct gcaaactgca aaaaggaaag acagacaaaa aatgatggag
     9901 cagcagaaaa gatgaacgac taaaaaacaa aaatactcct gtcgctttag attgggaaaa
     9961 tcaccaatct aggatgacag gagtatttat agtcatgttt atactagccc tttttggaca
    10021 gctaattgaa caagaacaac taatgtgttc attcctacgt gtgtgatcat cgatgtccag
    10081 atccgaccag ttgctttgta ctctaggctg aagaagaaac ctaggaaaaa gtagattagc
    10141 agatgaccat cattatgagc aaacgcaaac agcaaagagc tgatcactgc tccgacccaa
    10201 aaatttgaat atcgactgat gatccccagt atactgcggc ggaatacgaa ctcttccatg
    10261 atgggtccag caacagttgt cgccaaaata aaagcgggtg cttccatgat catctggatg
    10321 atattttgtg tattctcgga aggggttgct ttgccaaaca atacagattc taacatgaca
    10381 gcgatgcttt gcagaatcaa tgcgacaaag attccaacca atccataaat aacaatcttt
    10441 ggagcagaag ctttttttac cgctgattcg atcgctaagg gttcacgttg cttaaaataa
    10501 aaaatagcta ggacaacggc gcctagtata tacatgactg cagttgctgt gatcaattca
    10561 gacgtagatt ttacaagtcc tatcgaagct aggatcaagg gtgagataaa aattagacca
    10621 tagcaaaaaa tgctgaggaa gctatatttt tttaaagaca tgtaattcct ccttttaagg
    10681 gataacaagc atgcaaggca agcttatatc gattgatttc aattatatca taatttcaat
    10741 aagcagctgt cagaataaaa tttcttttct ttgatttaaa agcttgcaaa aaagagggag
    10801 aatgagtatt attaaaaatg taggttagca ctcgaaggtt aagagtgcta acagattaaa
    10861 aaaagagtta tcggagggat ttatcgtgtt aaaaccatta ggtgatcgcg tcattatcga
    10921 agtcgcaaaa gaagaagaaa aaactgtcgg aggaatcgtt ttagcttctg ctgctaaaga
    10981 gaaaccccaa actgggacag ttgttgcagt cggtgaaggc cgtttgttag aaaacggtga
    11041 aaaagttcct gccgctgtaa aagcaggcga ccaagttatg ttcgaaaaat acgccggtac
    11101 agaagtaaaa tacgaaggaa aagaatatct gatcgtcgca ggaaaagata tcatggcgat
    11161 tgttgagtaa atttggaaga taaaaaaata atcaaaaata atcaatgagg tgaatcaatc
    11221 atggcaaaag aattgaaatt tgcagaagac gcacgcgcag ctatgttacg cggggtagat
    11281 aaattagcag atacagtgaa agtaacatta ggacctaaag gccgaaatgt cgtactagaa
    11341 aaatcttacg gctctccatt gatcacaaat gatggtgtga cgatcgcaaa agaaatcgaa
    11401 ttagaagatc attttgaaaa catgggtgca aaacttgtat cagaagtagc atcaaaaaca
    11461 aatgatattg caggagacgg tacaacgaca gcaactgttc tgacacaagc aatcgttcgc
    11521 gaaggtttaa aaaacgtaac tgcaggtgct aatcctctag gcattcgtcg cgggatcgaa
    11581 ttggcaacaa aagcagcagt cgaagaattg cataatatct caactgttgt tgattcaaaa
    11641 gaagccattg cacaagtagc agctgtttct tcgggttctg ataaagttgg acatttgatt
    11701 gctgatgcaa tggaaaaagt tggaaacgac ggtgtcatca caatcgaaga atcaaaaggg
    11761 atcgaaacag aactagatgt tgtagaaggt atgcagtttg atcgtggtta cttatcacaa
    11821 tatatggtaa cagataacga caaaatggaa gctgttctag aaaacccata tatcttgatc
    11881 acagacaaaa aaatctctaa catccaagat attctgccat tgttagaaca aatcttgcaa
    11941 caatcacgtc cattgttgat tattgctgac gatgtagatg gtgaagcatt gccaactctt
    12001 gtattgaaca aaatccgtgg aacattcaac gtagtagctg taaaagctcc tggtttcggc
    12061 gatcgtcgta aagcaatgct tgaagatatc gctattttga caggtggtac agtaattact
    12121 gacgatctag gtttagaatt gaaagatgta acaatcgaaa acttaggaaa tgcttctaaa
    12181 gttgttgtag ataaagacaa tacaacgatc gtagaaggtt ctggagaaaa agaagcaatc
    12241 gaagctcgtg tgcaattgat caaaaaccaa attgctgaaa caacttctga ttttgaccgc
    12301 gaaaaattac aagaacgctt agctaaatta gcaggtggtg tagctgttgt taaagttggt
    12361 gcagctactg aaacagaatt gaaagaatta aaattacgca ttgaagatgc attgaatgct
    12421 acacgtgccg cagtagaaga aggaatggtc tcaggtggtg gtacagctct agtgaacgtt
    12481 atcagcaaag tttctgctgt agaagcagaa ggagacgtgg caacaggtat caagatcgtt
    12541 gttcgtgctt tagaagaacc aattcgtcaa atcgctgaaa acgctggtta tgaaggatca
    12601 gtgattgttg ataaattgaa gaacgtggaa ctaggcactg gtttcaatgc tgctactgga
    12661 gaatgggtaa acatggttga agcaggtatc gtagacccaa ctaaagtaac acgttctgcc
    12721 ttgcaaaatg ccgcttccgt ttctgccttg ttattaacga cagaagcagt cgttgcagat
    12781 aaaccagaac cagcagcgcc agcagctcct gcaatggatc catcaatgat gggcggtatg
    12841 atgtaagaaa aagcaacttg cttatctaca actgatcatt agtgaaagac agataaaaag
    12901 aggctggaac agaagcgttt aactccaaga aataagaaga aattcacgga aattgctttt
    12961 caaatttttg tgaatttcag cttatttccg aaggagttgc ttctgcttcc gctgtttata
    13021 cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt cccacgctct tttttgtgtg
    13081 taattataat gaaaatagtt atttttaata gttataatat tttatctatt aaaagtaaat
    13141 atccattca
//
LOCUS       DAPBBV010000063        13086 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.065, whole genome shotgun sequence.
ACCESSION   DAPBBV010000063 DAPBBV010000000
VERSION     DAPBBV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.065"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(80..2200)
                     /locus_tag="RD486_002485"
     CDS             complement(80..2200)
                     /locus_tag="RD486_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7664196.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2430..3608
                     /locus_tag="RD486_002486"
     CDS             2430..3608
                     /locus_tag="RD486_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HDT7664197.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3624..4382
                     /gene="aroD"
                     /locus_tag="RD486_002487"
     CDS             3624..4382
                     /gene="aroD"
                     /locus_tag="RD486_002487"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDT7664198.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4405..4890
                     /gene="ybaK"
                     /locus_tag="RD486_002488"
     CDS             4405..4890
                     /gene="ybaK"
                     /locus_tag="RD486_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDT7664199.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4961..6214)
                     /locus_tag="RD486_002489"
     CDS             complement(4961..6214)
                     /locus_tag="RD486_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7664200.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6330..7679
                     /gene="gdhA"
                     /locus_tag="RD486_002490"
     CDS             6330..7679
                     /gene="gdhA"
                     /locus_tag="RD486_002490"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HDT7664201.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7791..9137
                     /locus_tag="RD486_002491"
     CDS             7791..9137
                     /locus_tag="RD486_002491"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDT7664202.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9445..9831)
                     /locus_tag="RD486_002492"
     CDS             complement(9445..9831)
                     /locus_tag="RD486_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7664203.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10099..10248)
                     /locus_tag="RD486_002493"
     CDS             complement(10099..10248)
                     /locus_tag="RD486_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664204.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10710..10922
                     /locus_tag="RD486_002494"
     CDS             10710..10922
                     /locus_tag="RD486_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664205.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11200..12999)
                     /locus_tag="RD486_002495"
     CDS             complement(11200..12999)
                     /locus_tag="RD486_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDT7664206.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4292 a         2353 c         2577 g         3864 t
ORIGIN      
        1 attattctaa gatttctctt taccaacatc atttgacaaa gagcctaatt ttgtcgctgc
       61 tccttttaaa tttattttat cattcggaag aacttgtggt cgttccgtga agttcttggt
      121 acgtttgcgt tttataaaga tcaacagttg attgtccctt gtgttcacta aagacactag
      181 ttgacttgtc accaagagat ttttcagctt cttttaattt ctctaagcca ttcttgtagt
      241 cataatcact ggtatcaatt gggtctaatc cactattcgt atagaaccga agaagatcac
      301 cattattgat ttggtcagaa acagctaact gtttatcaac tttttctttc agtgaatcaa
      361 tttcattctg tacttcctca gtaggttcag taatagcttc accagtttcg ttactataga
      421 tcgtaccacc gtagtaagta tattttggtg taacaaaatc accatcacgg aaagaaacaa
      481 gctgttcatg atctttcgag aatagatctt gtcctaactg aatataattt tttgtatcta
      541 cacctagtaa gtgaagtaat gtaggcaagg catcaacttg tccgccgtaa gtgtgattga
      601 ttccgccctg tgtttgtcca gggatatgga tcatataagg gacacgctgc atttgtgcat
      661 tgtcgtagtt tgtccaagta gaacttgttt ttccaactaa ttcagctaga tttttatttc
      721 ttgaattcga gacaccgtaa tggtcaccgt aaaggacgat gactgaatta tcatacaagc
      781 cgctttcttt caaataattg aagaattctt gtacggcggt atctaaataa ttggctgtcg
      841 caaagtaacc gttgatcgtt tcatcatttg tattggctaa cgggaatcct gcttcgtcat
      901 tggtgaattt tgaataagga taatggttag atacagcaat gaattttgaa taaaatggtt
      961 gttgcagacg ttccaagtat tgtacggatt gttggaaaaa tggtttatca tgcaacccgt
     1021 attggaacga attgtcatca ttaacatcat aataagaaga atcaaagaaa taatcatatc
     1081 ctaaattctt gtatgtctcg tttcgattcc agaatgtacc agcgttccca tggaataccg
     1141 cactagtgta accttgtgtt tgacttaaaa tatcaggtgc agcttggaaa gtattttttc
     1201 cgcctaattg tgtgaacaag gagccttgat tcaagccaaa caatgaattt tccatcagcg
     1261 tttccgcatc gcttgttttt cctgctttta cttgatggaa aaagttgtca aaactgaacg
     1321 tgctgttgct gtggtaaaga ctattgatga aaggtgtaac ttcaagctgg agaccattct
     1381 catctgtcaa tttataatcg atcaggaatt gctggaagct ttctaaatgg atataaatca
     1441 cattttttcc tttagcgagc ccgaacaaat catcatttgg tgctgcataa tgttctttta
     1501 cataattttc tacttctttc atatcattgg gacttgcttc tgcccgcact tggtttgtct
     1561 ggtaagtttg aacaccgtca taaaccatga aagcattcaa gccaagatat ttgaccaaat
     1621 aatcacgaga gaatgttcga gtcagcaatt ctggacgatc agcttccgcc ataaaaagat
     1681 ttcctgagaa aatcataact gctaatgtag agatcgcaaa agccattctt gctcggatcg
     1741 ggcgagggtc caacttgatt ttttttgcaa tcagcagaac agtcaagata ataaaatcga
     1801 tccaatagat cacatcatat gggcgaaaca gtcgaatggc actttctccc agaccactcg
     1861 ctactttccc agcacctaaa atcgtgttga tcgtaatgaa gtccgtgaat tctcgataat
     1921 aagtgacatt cgaaaaaaca agcaatgtca aaagaaaata aatgaccatc atcgtgatat
     1981 aagcaactct agggcgtctg atataaagag caattccaag taataacaat gtagttgcaa
     2041 tagggttgat aaacaagata aagtattgaa tgccactttc gattccgaga tggaaatcaa
     2101 ctaaataggc aaaaatcgtt ttcaaccaaa gtaaaacaac tagtaaagaa aaaaatccga
     2161 gcctcttatt caaaaaggca ggtgttttta tacatttcaa gataatcttc ctttctgcac
     2221 ttcttaatca cagaagtgtc atgaaaccat gttacacagc tcacttattc tcatttattt
     2281 tactagtatg acaatatagt gtcaattgaa accagaagtt tatgctgttt cattaaggtt
     2341 ttctttaagc ttcatgaaaa aatgagcagt aagacaagtc ctatgttttt tgttatactt
     2401 gggaagagaa agctaaagca ggtgaaggaa tgaaagtaaa agtaaaaaaa agagcaagca
     2461 atcgattgaa aaaaggatat ccactgatcc aaaaagaaga ccttgctcat ccccaaaaag
     2521 aaaccacgca atgggtggaa ttagttgatt cgcaaaacca atttatcgca aaaggatatc
     2581 taggaaagca gaataaggga atcggttggg tattgagcca gcagaacatc ccatttgatc
     2641 aatctttttt tgaagaattt tttgtgaagt caaaagaaaa aagaactttc tttttttcag
     2701 atgattctac taccgctttt cgtatattca atggagaagg agacgggatc ggcggtctga
     2761 ttgttgatta ttatgcaggt tatgctgttt tttcttggta taacgaaacg ttatatgcac
     2821 atcgtgaatt attgattcaa gcttttcgtg aaatctaccc ggaaatcgta ggaggctatg
     2881 agaaaattcg atttgaatca gtaaatctgc ctgagagcca gttcatttac ggaaaagagg
     2941 caccggaacc cttgatcgta aaagaaaacg gagtaaaatt tgccgtttat ttaaatgaag
     3001 gattaatgac tgggatcttt ttagaccaaa aagaagtacg gggatcatta gcagaaggtt
     3061 tcgcttctgg gaaaacagtt ttgaacatgt ttagttatac cggcgccttt tctgttgctg
     3121 ccgcaatggg aggggcaatc gaaacaacaa gtgtcgatct agcaaaacgc agtttaaaaa
     3181 aaacacagga acagtttgaa gtgaatggtt tggatgtcga tcagcaaaaa atcattgtta
     3241 tggacgtatt cgagtatttc aaatacgcca aaagaaaaca atttttatat gacatgattg
     3301 tattggatcc accaagtttt gccagaaata agaaaaaagt ctttcgcgta gcaaaagatt
     3361 atggggaact ggtcaaggat agtctggata ttttagcaga agacgggata cttattgcgt
     3421 ctacaaatgc tgcgaatgtc tcgatagaac aattccaaac aatgattgaa gaggaattcc
     3481 atgccaaaaa tgtttctttt gaacaacttg ctttatatcg tctgccaaaa gatttccaga
     3541 cgacggatac ctttttagaa ggcaattatc tgaaagtgtt tgtttatcaa attaaaaata
     3601 accattagaa ggagcgatgc agaatggttt gggtaaaggg attgaatata ggaagcggta
     3661 gaccaaagat ttgtgcgcct cttatcgggg ccgtccgaga ggaagtatta cgtgaagcag
     3721 ttcttgcacg tgaagcaggg gccgatttag tcgaatggcg agtcgatcat tatcgtgaag
     3781 ttttttcttt tgatgaagta gcagaaacat tggttcttat ccatgagatg cttgatggac
     3841 tgccgttatt atttacgttt cgtaccttag ctgaaggcgg agaacaagac atatcgatcc
     3901 gtcagtatcg cgacctttat gaacatgtga tacacacagg attagtagat atggtcgata
     3961 tcgagttgtt caaagtagaa agtctaggaa aaagactgat agaggaaatc aagtctttaa
     4021 acattccttt aattatcagt agtcatgatt ttaaagaaac accagcagac cctgtcttgc
     4081 tttaccgatt gaatgttatg gaacattttg gagccgatat cggaaaactg gcagtaactc
     4141 ccaataatga acgagatgtt ttgcggttga tggagttgac tagacgggca aatgcttttg
     4201 tctccatgcc tattattacg atgtccatgg gaaatcttgg taaaatttct cgtctggctg
     4261 gcggaacgac gggttccgtt atgacatttg gttccttaag cagcgattct acttctgctc
     4321 caggacaatt accggtcaaa gcattgaagc aaattattca attattaaat gaaccgttgt
     4381 agaacaagtt tgaggtgata ttttttggca aagaaaaaaa tagtaaaaac gaatgcaatc
     4441 cgtatggtcg aacaaaaaaa gattccctat acagagcacg aatatgagtg ggacgaaagc
     4501 cacctaagtg cgtcatcggt cgctgaacag cttccagaaa gccaatctca tatatttaaa
     4561 acactggttg ctgtgggcaa tgtgacgggg cctcttgttg ctgtgatacc gggagaagcc
     4621 gaattgaatc taaaaaaatt agcaaaagtt tcagggaata aaaaagtaga aatgctccat
     4681 ttaaaagatt tggaagcaac gaccggatac atacgtggtg gctgctcgcc tataggtatg
     4741 aaaaaactat ttcctactta tttagatcaa attgcagaaa gctatgaaca aatcattgtc
     4801 tcggctggca gaagagggct acagatggag ttagcacctc aagatatctg tgcattaacg
     4861 agcggacaat ttgcagatat aaaacaataa atcatacgta taaaagaaag aaggaggccg
     4921 ggatgttgtt tgtccagtct ccttctttct tttttataca ttatgctctt tgcccggcat
     4981 tcattcctgc tacatgccct gtagcgaaag ccgctgtgat attaaagccg ccagtataac
     5041 cattgacatc cagtaattct cccgcaaaat acagaccatc aatgatttta ctctccaatg
     5101 ttttaggata aatttccttt agagaaaccc ctccgccagt tacaaatgat ttctcaatag
     5161 gaaaagtttt gttgattgat agcttaaact ctttgcatag ttgaacaaaa tcttgaattt
     5221 gtttttgaga ggcttgttgt cctgtcagat gatccatttc aagccgctca agaaagaaaa
     5281 ctaacaatcg ctcaggcaat ataccatgcc aagcattgac caagttcttt ttggttgctt
     5341 tacttttttc tgtcaatata tgaataagct cttgtttggt ttgtgtaggg aaacaatcca
     5401 gagaaagtgt cactggttct cccgttttct ctaattcttt attgacaaaa cttgaacaac
     5461 gcagtgcagc cggaccagaa ataccgaaat gggtgaaaag taaatccatc gtatgttcag
     5521 tcaatacacg acctttttta tttaaaacgc gtaaagtgat gtcttgtaaa gaaagccctt
     5581 gaagtgtttt ctcctgaata tacggttcat ccgatatcaa gggggactct gtcgcataaa
     5641 gaggcgtcac cgtgtgaccc actcgcttca cgatcttgta cccatctcca gtagaaccag
     5701 tagatggata agtccgtcca ccagttgtta agataatggc aggagcatgg aactcttcga
     5761 attccgtgcg tataccgtaa attttatgtt ctttgtggat caatttctct actcgagtag
     5821 agaatagaag cgtcacatct agttctttca gacgattgag caatgcttcg ataatcgttt
     5881 ttgatttatt tgttacagga aacatccgtc catgatcctc ttcttttaaa tgtacgcctt
     5941 gtgattcaaa gaagttcatg atatcgaaat tattccattg cgcaaacgta ctatataaaa
     6001 actttccatt tccaggaata tgtgcaatca aatcatcaac aggacgattg ttcgtaacat
     6061 tgcaccgacc accacctgtc atcagtagtt tttttcctgc ttttttgttt ttttcgatca
     6121 agagtacgcg tgcgccttgt tcagctgcac tgatcgctgc catcatcccg cttgttccag
     6181 cgccgactac gatcacatca tacagttttt ccattccctc acctcaagga aagtgtagca
     6241 tatctgaaga aagaaaacag aaaaaatgtt ttgagccaaa agagaaaatg agctaaaatg
     6301 agggaagata agcaaaggag cgtggaacga tgacaaacgc aacagaatat gttcaagcaa
     6361 ttcaagaaaa gctacatcaa aaggatcaag ggcaagaaga atttttacaa gcaatcgatg
     6421 aattcatgcc cacggttatg tcttttttgg acactcatcc cgaatatatc gaaaagaata
     6481 tcttagaact tttaacggaa ccagaaagag ttattcaatt tcgagtgcct tggcaagatg
     6541 atgaaggaaa ctggcgagta aatagagggt accgtatcca atacaactca gctatcggcc
     6601 cttataaagg tggattgcgc ttccatccta gtgtcaatct aagtatcttg aaatttttgg
     6661 cttttgaaca gattttcaag aatagtttaa ccggtctgcc aatcggtgga ggaaaaggcg
     6721 gaagtgactt cgatcctaaa ggaaaatctg ataatgagat catgcgtttt tgtcaaagtt
     6781 tcatgctgga attgtcaaaa catatcggcc catcgattga tgttcctgcg ggagatatcg
     6841 gtgtaggagc tagagaaatc ggctatttgt tcggcgaata taaacgattg aaaaaatatg
     6901 atactggtgt gttgacaggt aaacctttgg atttttgggg aagtaagata cgtacggaag
     6961 ctactggtta tggattagtg tattatgtca aacatctatt gaacgaagaa aaagattcat
     7021 ttaatcaaaa aacagttttt gtttccggaa gcgggaatgt agccatttat gcaatcgaaa
     7081 aagtgcaaga gctaggcggg aaagttgtta catgttcaga ttctagcggg tacatctatg
     7141 atccagaagg aatagatgtg aaactattga aagaagtcaa agaaatcaat agacaacgtt
     7201 tgacggaata cgcaaaccaa cgtccttctg ctatttatca tgctggagaa tctgtttgga
     7261 cattgaaaga aaaagcggat atcgctttgc catgtgctac tcaaaatgaa atagacgaaa
     7321 gcttggccga aatcttagta gaaaatggga tcaaaatcgt agcagaaggc gctaatatgc
     7381 catgtacagt aaaagctgtt tctgttcttc atgaagcagg cgtgtggtat tgtccaggaa
     7441 aagctgctaa tgctggagga gtagcagtat ctgctttaga aatgagtcag aacgcccagc
     7501 gattgacttg ggaaagagag caagtggatg agcagctgga tcaaatcatg gaaacgattt
     7561 accatacgtg tcgccaaaca gcagccgagt acggcgacga aaaaaatctg cttcttggag
     7621 caaatgttgc tggatttgaa aaagttgcca aagcaatggc agcagaaggt ttagtttgaa
     7681 aaatgaaact ttcttggaaa tattgtcagc attttgttta tttgcttgaa aaataataaa
     7741 aaaaaacgta aagtattacc tgtagagtaa acctataagg aggagaacaa atggcacaca
     7801 ttcattttga ctattcaaaa gtagcaccgt ttgtcaacga acaagagtta gggtacatgc
     7861 aaagccaagt aacagcagcc cacaacgaat tacgggaagg tactggcgca ggaagcgact
     7921 tccgcggctg gatcgattta ccaacgaact atgacaaaga agaatttgca cgtatcaaag
     7981 aagcagctaa aaaaatccaa tctgattctg aagtattagt tgttatcggt atcggtggtt
     8041 cttatttagg cgctcgtgca gcgatcgact tcttgaatca cacattcttc aatttattag
     8101 atagcaacac aagaaaagca ccacaaatct tctttgccgg aaattcaatc agctcaacat
     8161 atattgctga cttgatcgaa gtaatcggtg atcgcgactt ttcagtaaac gttatttcaa
     8221 aatctggaac aactactgaa ccagcgattg cgttccgtgt attcaaagag cttcttgtta
     8281 agaaatatgg acaagaagaa gcaaacaaac gtatctacgc tacaacagat aaagcaaaag
     8341 gtgcagttaa agtagaagca gatgcagaag gttgggaaac tttcgtgatt cctgatgaca
     8401 tcggcggacg tttctctgta ttaactgctg ttggtttgtt accaatcgct gttagtggtg
     8461 cagatatcga tgcattgatg caaggtgccg ctgatgcaag caaagcatac tcaagcgaca
     8521 aactagaaga aaacgaagct taccaatacg cagcaatgcg caacattctt taccgtaaag
     8581 gcaaagtaac tgagttgttg atcaactatg aaccaggaat gcaatacttc tcagaatggt
     8641 ggaaacaatt gtatggtgaa tctgaaggaa aagaccaaaa aggcatctat ccttcaagcg
     8701 caaacttctc aactgatttg cactctttag gacaattcat ccaagaagga cgtcgcaata
     8761 tttttgaaac agttgtgaag gttgaaaaac ctcgtaaatc aatcacaatt cctgaacaag
     8821 cagaagattt agacggtcta ggctacttgc aaggaaaaga agtggacttc gtaaatacaa
     8881 aagcatttga aggaacattg cttgctcata cagacggtga cgtgcctaac ttgctagtca
     8941 aaattccaga aatggatgct tatacattgg gttatacaat gtacttcttt gaaattgctg
     9001 taggtatttc aggttacttg aatggaatca acccattcga ccaaccaggt gtagaagctt
     9061 acaagaaaaa catgttcgca cttctaggca aaccgggctt tgaagatctt gctaaagaat
     9121 tgaacgaacg cctgtaagat aagggttttt cgctagattt aaataatcag tgatagaaac
     9181 atgttcgctt taaaatgaaa actggtaccc atttaggtac tcaaacatac tgcatcgttt
     9241 attcagaata aggggctgtg acaagacgtt tgtcacagtc ccttgtttgt atagaaatcg
     9301 attgattgcc ttgctcttta gtttgtttta ggactttaag aacagtgagg ctgacttcga
     9361 aggttaattc tgtttttttg ttttctagaa tcagtaagca aaaaagcact cacttcgagt
     9421 gcttttttgc gatatattct tagcttaaga taggcctaat ttttctttta cagatgaggg
     9481 taccttatcg ctggtaatta cttttttctc tatgatccgc ttttcgcttg ctttcaactg
     9541 caagatcgtt ccttcggtgt aagcagaacc attggcagag tcaccagaag taatgacatc
     9601 gaaatctaac tgtctttttt caccgttttc agcataagca tctacgttgt atttaaaacc
     9661 tcttccaatt acttccccat tatctgcttt gatatcagtt tctgcaggca ttggagcttt
     9721 gactaccgca taataatctt tacctacata agtagactga tagtagtccc aacctttcca
     9781 tcctataaaa gcaatcaata tgataacgat caaccctaaa atttttttca tgaaagatct
     9841 ccttttttat ttttattata ttaaatatta tacagataat aacggaatat tatcatcgaa
     9901 acagctaaca aaattgtcat aaaaaacgag atggttgata ttagaacttg tgtttttgtt
     9961 taggtctaga gataaagaga gacaatttcc aaatatatgt aatgaataca aaaagacgtt
    10021 tgtcgcggat taccgttaca aacgtctttt attgattttc cgagatctca tcagtcgcca
    10081 tttggaatgg ttcactcctt atctagattc gtttaatgct cggactgctt gttcgattgt
    10141 aataccaaac gcaacgttat tttcgttttg tgcatcaatc gccataaaac ggttagaagt
    10201 tgtatcaaaa gctacgcggt attgcatatt tgtttttgta aacgtcataa aattcatctc
    10261 ctttgtaatg taatttagtt cttgaaagtt tcctttaaac tttcgaactt ataccaagtt
    10321 tagcatcgta cgttttttga tgcaattaaa aagcatttat cattttcctt atttattttt
    10381 tcttaaatgg tttagctatt ttcttttaat ccgataagta gcccaatcat caaggttaca
    10441 aatactattg cttgaatata aatcatatgc tcacctcttt ataaataact tagcaatata
    10501 aagaaaaaaa cgcacgaaca acataggaat ataaacaaac gtttttgtca caacgtctaa
    10561 gatcgtgtta aaaaatagtt atctaaaaag cagaaagata ctcaaaataa aaaataaaaa
    10621 aatgaataaa aacgttttca aatacaaggt aatttgttat tataaaataa agaaaaaaca
    10681 aaataaaaat aaagaaaaga gggaatgaaa tggtaaaagc agaagtagga agatcttata
    10741 tatgcaaacc gatcggagta tctcatgaac taatcggctg tattgaacgt acatatatca
    10801 acacggctgt cgtgtatgtt gaaagttatg accaacgaga ctatcaactt atcaatgaaa
    10861 gcaagtatcg catgctcgta aaattctgtg atattagcgc acctactgaa ttggtttctt
    10921 aaacagtatt tttgagaatt cgcaagaact cccttataat ataaataaag acagaaggga
    10981 gcgagaagat atgccaaaaa gaaaaagttc agggaaaatg ggaattattc ttgcagtgat
    11041 ctctgcaatt cctgctattt tagctattgt tcgtgcgatg aaggaatcaa gagaaagtta
    11101 agcacacatt atgagcgtca aacaaaaaac gcatatacct gcggtggcag gttatgcgtt
    11161 ttttgttgta taaagacttt tttcattaac gatttttgat tagccgactc ccaaaacaaa
    11221 atttagcagt ttatctgaat aagtgatttc ttcatctgtt tgtttcacac tttcatttag
    11281 tagtcccatc tcatcggtta tgataccatc cacaccataa aacatcatgc gactcatggc
    11341 atctgaatcg ttgattgtcc atacatatac ttcttttccg tcttggtggg cagaattaat
    11401 gaagttacgg ttgatcgtac tatattccat tgtcagaaaa tcagcaggcg tcacaggggg
    11461 cccaacaata ttgaaaggta agatgtagcc cacataaaag tttggttctg cttcttttaa
    11521 atctgaaacg gtttggtacg tcaaactttg caaaatatga tggttctcta agataacttt
    11581 gcggtattta tggacaaatc gttcgacaag gtcatccgaa tcttttttag aggtcttgat
    11641 ctcaataagt aatttttggt ttagcttatg tgctttttcc aaataagaat caaaagaaca
    11701 aacaggggct tgcactccgt tttcagtaac tgtaagattt gtcaattctt tcaatgtaag
    11761 atcctgtggt gttccattta cccctgttaa gtgacgaaga tttgcatcat gcatcactac
    11821 gaaatgacca tcttttgttt cctgaacatc catctctaca taatcaggat gatagtctct
    11881 gcttgttttt tcaagtgctt ctaaagtatt ttgcgcccca ttttgggtac tcacacctct
    11941 gtgagagaca gtcactggtt ttgtctgaac agctgaagtc agataatcca tattgtaaag
    12001 acagacgcca ataccgaaaa aaactgcaaa aagagtcaaa ccagtgtttt tcagcgcaga
    12061 gaaacgcaag ttgggggctt gtgggataaa ccacttaggg atctcaggca agaagccttc
    12121 gtcatccatg aaatcaacaa tgatataaaa aatccctacg gtagacatca cgatattgaa
    12181 taataaaatc ccttgtaaaa gcgtcatagc aaacacagcg ctgatcaatg catagtctgg
    12241 gaaaaattgt tcaaccatac tttgtgccaa aataacaacg atatatccta aagaagaaag
    12301 gagtaaaatc gtaccgccaa tcacaataaa ttggcccgtg atggccaaaa gacgcgattt
    12361 ggtcaatgac cagctttccc gaatggctgc tcgaaaagaa cgatctcgta gaatcatttc
    12421 cggtaaagca aaaatcagtc gaatcccaat atagccaagg aaaatataaa cgagtaaaaa
    12481 ggaactgacg atgatccaac gattagcaaa aataaaatcc ataatgaaag cggggatttt
    12541 tatttttgac agtagatcag aattaaaact taatccgctg atcggtagaa tcaataaaaa
    12601 ataagcaagg aaaaacaaaa aagtaatggg tctcactttc ttcagctgaa gtatcgtcaa
    12661 gtgtaagagt tgcttcaaag agattggttc tttcttttta ataaaaaaaa cactcatcaa
    12721 aagaaaagta aattcgaaat aaactaacag taaaatcgtc atcaaaacta cgattaacga
    12781 gagtagaacc ccaggatgtt gagaaaaaat tgaaggaata ttgtcataag acaaatagtc
    12841 aattgcccct cggtgtaaaa taaaacgggt cgtactgctc aataagggta aacaaataaa
    12901 taaaataaag ccatgcatca gcaagacatc acggaaataa gcttgtgttc cttttaaaaa
    12961 gtcccaagca ttacctaagc tacgtttcaa ataattcatc ctatcacctg ctcttcacat
    13021 tgtagcgcaa atctaatgaa aaaggaaagg gtgcagtgtg ttttgcagac cctttcccag
    13081 atttaa
//
LOCUS       DAPBBV010000064        12576 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.066, whole genome shotgun sequence.
ACCESSION   DAPBBV010000064 DAPBBV010000000
VERSION     DAPBBV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.066"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            4..2376
                     /locus_tag="RD486_002496"
     CDS             4..2376
                     /locus_tag="RD486_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664207.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNDQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     TPTDSVKEKETDHFYRVEFNENDPAKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELARLCEQVPEKEQKQTVKNEPISKV
                     QNEIKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGHTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     ATWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQD
                     EKNVVETAEQKNIVLVGSLWIDKKDGKVLEEDTGRTLHLKDAAFIEDTQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="RD486_002497"
     CDS             2437..3897
                     /locus_tag="RD486_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HDT7664208.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPDWLIDYAEKEGLIAELKPKHERQNF
                     LVQDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEMKVEPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKGCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIHQQEIRKQKRAMLFQQGKQQERE"
     gene            3908..4351
                     /locus_tag="RD486_002498"
     CDS             3908..4351
                     /locus_tag="RD486_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
                     /protein_id="HDT7664209.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQ"
     gene            4436..6112
                     /locus_tag="RD486_002499"
     CDS             4436..6112
                     /locus_tag="RD486_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HDT7664210.1"
                     /translation="MNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRNFQ
                     KEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVETE
                     KKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAIQGLYEGKYLSYPRTDTPYITEGEY
                     AYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQLS
                     PLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPLDLGWKKLFGKES
                     DGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSEEA
                     QSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLTSA
                     EMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKAAS
                     EKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEIIQN
                     SRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTAK"
     gene            6128..6277
                     /locus_tag="RD486_002500"
     CDS             6128..6277
                     /locus_tag="RD486_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664211.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6358..6954
                     /locus_tag="RD486_002501"
     CDS             6358..6954
                     /locus_tag="RD486_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HDT7664212.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDTERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            6967..7866
                     /locus_tag="RD486_002502"
     CDS             6967..7866
                     /locus_tag="RD486_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HDT7664213.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKEQKLAYQRHQQMNREMER"
     gene            7869..8353
                     /gene="ssb"
                     /locus_tag="RD486_002503"
                     /pseudo
     CDS             7869..8353
                     /gene="ssb"
                     /locus_tag="RD486_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            8375..8632
                     /locus_tag="RD486_002504"
     CDS             8375..8632
                     /locus_tag="RD486_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664214.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(8791..8925)
                     /locus_tag="RD486_002505"
     CDS             complement(8791..8925)
                     /locus_tag="RD486_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HDT7664215.1"
                     /translation="MLKSIKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK
                     "
     gene            9068..9328
                     /locus_tag="RD486_002506"
     CDS             9068..9328
                     /locus_tag="RD486_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664216.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9777..9983
                     /locus_tag="RD486_002507"
     CDS             9777..9983
                     /locus_tag="RD486_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HDT7664217.1"
                     /translation="MRKKFDYLGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIEEKGKKR"
     gene            9983..10234
                     /locus_tag="RD486_002508"
     CDS             9983..10234
                     /locus_tag="RD486_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664218.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGCELHYQENLETYENEYWLTKLEN"
     gene            10250..10687
                     /locus_tag="RD486_002509"
     CDS             10250..10687
                     /locus_tag="RD486_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664219.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCFEIGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            11123..11311
                     /locus_tag="RD486_002510"
     CDS             11123..11311
                     /locus_tag="RD486_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664220.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IACIGQYLYCIRGRKLYA"
     gene            11369..11635
                     /locus_tag="RD486_002511"
     CDS             11369..11635
                     /locus_tag="RD486_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664221.1"
                     /translation="MGTGFIDRVLVQVKEERKITMKYNLLDHKRMWVEKLEEDLEQLE
                     LLGHNKTSTVYKEGLKRTKKAQKELATLESRVQKKEVDLTHTYL"
     gene            11645..11878
                     /locus_tag="RD486_002512"
     CDS             11645..11878
                     /locus_tag="RD486_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HDT7664222.1"
                     /translation="MADKRKEKIQKLLALAADVNDEESVSALAKAQQLMMDYDLTEDE
                     IFNYHEQQRIEAVETHVIYRGRPQKWLYRLFRN"
     gene            12200..12403
                     /locus_tag="RD486_002513"
     CDS             12200..12403
                     /locus_tag="RD486_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HDT7664223.1"
                     /translation="MILGIVLLSVSTLGITVDAATYYGNGVYCNTQKCWVDWSRARSE
                     IVDRGVKAYVNGFTKVLGGVGGR"
     gene            12393..>12576
                     /locus_tag="RD486_002514"
     CDS             12393..>12576
                     /locus_tag="RD486_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664224.1"
                     /translation="MEDKKEKLFDLIANAYNSKSYNNVEVKEGFLQDAKKIREDKPYP
                     EIIISVYKHLSKLKAEE"
BASE COUNT         4655 a         2076 c         2644 g         3201 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaatgat caaatcgaaa agatgtttga acaccaaaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaacgggc attcttggtt taggcaacaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gttataacaa gtacggtggc
      301 ctggatatga cgatcgaaaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc tgccacgatc cgaaaatacc aacgaaaatt ggaaacatta
      421 gaacagctga aagaaaaatc agagaaagga aaagaaaata ttcttcctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaagaatc caactatcta ttttctgaaa
      541 ggctatcgaa aagtcgcttt agaactcaat gaaaacgggg gatttgagga atctaaaaaa
      601 taccaagcca cgtcggaaga agaaaaggca gctgttcgtg aattacttga agaagctaca
      661 cctactgatt ctgtgaagga gaaagaaacc gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag caaaagggtt gaaaagttat ggtggggaga tcgtaacact agaattgatc
      781 gatcaactca aaacactgga taaccaatac gccgcagaag caggctatta taaattctat
      841 tttgaagaag tgaagaatgg agaagtagta gatcagatac gaatggatct aggggatggc
      901 gtcaatagta atcaccccat ctatttagag ttagctagat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaaacagt caaaaatgaa cctatttcaa aagtacaaaa tgagattaaa
     1021 gagacaaaaa caaaacaaaa gggttatcaa aaacgaacgg cagaagagat taagcaagaa
     1081 gtcaaatcac tttcccaaca ggcgcttgat gcggtgaaaa agcatactca ttcacctgaa
     1141 gacgtcaaag aacttttgaa ttttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgatcg aggaacaatt tccaggcgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaggc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacaa ttgaagcctg aagactatcc gaaaatcttc
     1501 ccgaaccgcg tctttgattt tcaattggat caaacagggc atacagaact tcaagttggg
     1561 attcaagcgg tagccaaaaa tattggaatt caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtacgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagccac aagtattcac
     1741 gaattagccc atgctagaat gcacaaattt tcagaattag atactgcaac aaaagaacta
     1801 caggcagaaa tgacctccta tattgtgtgc aagcattttg ggatggacac ctcggagaaa
     1861 gctattcctt atattgcgac atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agtcgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccagcc agcagaagtg
     2041 aagcaggatg agaaaaatgt tgtagaaaca gcagaacaaa agaatattgt gctcgttggc
     2101 tcactttgga tcgacaagaa agacgggaaa gtcctggaag aagacacggg ccgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat acgcagcata atcaagtgat tttaaaagga
     2221 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gattcaagac tctaagcaac aatttaaagc agccacagat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtagaaa atcttcattt tgagacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatttg
     2821 aaggaagaac gaaaactgcc cgattggttg attgattatg cagaaaaaga aggattgatc
     2881 gccgaactaa agccaaaaca tgaacggcaa aatttcttag ttcaagacga tcgtttggat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacat tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggatttaac ctaaagatcg gtgaccctaa acagttaaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccattga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagttgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aagtcattta tgaagaagtt gcaaaagaaa tgaaagttga acctgaagca
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgtcttt tggtcagcag ctttctgtta acgattcaat agaagctatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aaggttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc tcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggattg gaatgatcaa ttgaagcatg aaatccacca acaagagatc
     3841 agaaagcaaa aacgtgcgat gttgtttcaa caaggcaaac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccaccc gaaaagacgg gtattttgaa atccaagata gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gagttagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agagcatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatagcttg
     4261 gacgatcatt caacaagcag gcgccgatca tggaaagata tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcagtg attccagcaa ttacgagacg cagaagagac
     4381 ctatcccaaa tttgaagaag cacaagcacg ccagatcgct gattggttga tcggcatgaa
     4441 cggcagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gtttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcag ctgcaggaaa agattagaaa
     4561 cttccaaaaa gagccttatt ttgaaggaaa agcccaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggtacg atccaccaag ttgaaaccga
     4741 gaaaaaaagt gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagatac tttggaagcc atacaagggt tgtatgaagg
     4861 gaaatatcta agctacccac gaacagatac cccttatatt acagaagggg agtatgcgta
     4921 tctgttggat cacttagacg aatacaaaca ctttttaaag gccgaagcca ttcctactcc
     4981 tattcataca ccgaatagtc gatatgtgaa taataagaaa gtccaggaac attacgcgat
     5041 cattcctaca aaaacggtca tgacggcagc ggcttttgaa caattaagtc cactgcagca
     5101 ggccatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ttaaaggcaa tcggaaaggt
     5221 gccgctagat ctaggttgga agaagttatt tggaaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtgg atctacaagt
     5341 tcttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcaat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agctcgtggt gacgaataaa gggattttgc tttgccaagc
     5581 cgtggaaaaa gagccgctgc ttacgagcgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatc ggtgaacgaa aaggaacaca aaccactttt ctagccaata tccaaaaatt
     5701 tgtctctcac ttattggaag tcgtaccagg gcaaatccaa tccactgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttgct ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatc attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcattt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgccgc actgcaaaat aatggagggt
     6121 taatcttatg cgtaatacca cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caggaaaaaa tgcgtgccag caaacgaaga ctgcagcaat tgaagaacca
     6241 gcagaggatt caaaaagaaa tcgaattaga tcgataaaat cttcctaact attgtatacg
     6301 tataaactta tgttatactg tttttataag tttatacgta tacaaaggag ggagaaaatg
     6361 acaaaagcaa tggtatacaa gctgctagaa gaatttaatg gaactttggc tttgaaggat
     6421 gccaaaaaag cgggcatttc tcctgtaacg atcaaacgta tggtagatcg aggggagctg
     6481 gatcgagagt atccaggttt tttcacctta cctggtcaat ttcctgatga attgtttatg
     6541 gcgcaaaaaa aatatgaacg cggcattatt tcacatatta ccgcgttaga tttgtatgat
     6601 ttaacagata tgatccctag acagatcgat ctgactgtac cttacggtta tcacgtttct
     6661 gaaaaaggat tgaaggaatt cgcagttgag ctacactata caaaagcgga atggtatgaa
     6721 ttaggtaaga ttgaaataaa aagtcgctat gggaatccta ttatagctta tgatacagaa
     6781 agaactttat gtgacatttg gaatccctgg tataccgttg aggatgaaat caaagtaaaa
     6841 gcaatcaaaa actatatgga gtcggacaga aaaaatctta gaaaattgaa tgagtatcga
     6901 cgaattttac caacagacaa aacgatgcgt tcttatatta tggctttaaa ttaaaggaga
     6961 agatacatga cacctacgca gttaaaagca aaagtgaaga atatttctag agaaaaagaa
     7021 gttgatccgc agcttgtttt aagacatttt atgatggaaa aattcttgga aaaaatctca
     7081 gagtctcctt atcgtgaaaa ttttgtgtta aaaggcggct tcttgattgg ctcaaagtat
     7141 ggcattgaaa atcgcacaac caaagatatt gatacgactt tacgggaaat gaaagtaacc
     7201 aaagaaacat taacaacggt tctaaacgaa attttttcaa cgccgacgaa agaaggcatt
     7261 caatttgaga ttcaaggaat gaaagaaacg agagaagccg attactatcc aggatttagc
     7321 ttacgtgtgc tggcacattt ggaaaacatg cggccagatt ttaaggtaga tgtgactaca
     7381 ggtgactcga tctatcctgc aacgatcact cacagtcata aattgatgtt tgaggatcga
     7441 acgattcctt tggaatccta tcctacagaa caaattattg ctgaaaaatt aagtgcaacc
     7501 tttgattttt taacagataa ttcgagagga aaagattttt atgatctcta tactattcct
     7561 aaaatggaga agatcgatga gaagaccttg aaagatagtg tgagaaatac atttacacgt
     7621 cgaggaaaaa ctgatccgtt aaagatatac tatgaaaagg atatggatgt actgaaaaat
     7681 agtcacgagc taaaagatac ctggaagaaa tatcaaaaaa gcaatcctta tgctgcatcg
     7741 atcacgtacg atgagacaat ggattcgatt agtaatttga tggaaaaagt gattcacgtc
     7801 gaagaaaaag agcaaaaact agcttatcaa agacaccaac agatgaatag agaaatggag
     7861 agataaagat gattaataat gtgacattag taggacgctt aaccaaagat cctgatttac
     7921 gttataccgc aagtggtact gcagtagcga cttttaccct agccgtcaac cgaaatttca
     7981 cgaatcaaaa cggcaatcga gaagccgatt ttattaactg cgtgatttgg cgcaaaccag
     8041 cagaaacaat ggcgacatta gctaaaaaag gtagcttgat tggtgtagtt gggcggattc
     8101 aaacgcggac ttacgacaac cagcaaggac aacgtgtata tgtgactgaa gttgtagcag
     8161 ataactttca actattagaa aataaagcag cgacagagag ccgtgcgcac gctgatcaat
     8221 cgtccaccag tccaagcacc gccacctttg aacaacggat acagcgacgc ctaacaacaa
     8281 tggattgaac gcttcacaga atccatttgg tggacaatca atcgatatta gcgatgatga
     8341 tctaccgttt tagtttgaga aagaaggagt aagcatggca aaaaaaatta gtctgacgat
     8401 ggatctattg atacccgtaa ttgcatttat agacgggatt tctttgggcg tcactgaaaa
     8461 tcctttggta aatagaattg cgaaaggatc actatttctt gtattcgtgt atcttgtctg
     8521 ttcttatctt ttaaaaagag caggaaagga taattccttt tggcgattga ctaaagtcac
     8581 agtagcagcg acagctgtta tacttacggc tattctaccg ctttatatgt agagttaacg
     8641 ggaaatcgtt gaacttcttg cgaaatattg ctataatgaa catgaaaaag aggagttgcg
     8701 ctaacaaccc ctcattaaca gcaccgatta aagaacggtg gcagaatatt agttatttgg
     8761 aaataaccgc tgacctgcta aagtagacgg ttatttcttt ttgtcatttt taagcatatt
     8821 tacaatcaaa ctaatcaaag caatggtaaa cataccaaaa ccaagaatgg tttgaattgt
     8881 ctcatatgcg gacaaaaggc ttactccttt tatagatttt agcacttaca ttcataagca
     8941 ccaccacctt tccagaagtc gccaccgtct tcaaacttta ctgtcttgac tattatagca
     9001 tatctaaaat cgaataaaaa ttctcaattt taactgtttt tgctataatt ttagcgaggt
     9061 gatcgtgatg aacaaatatg ttggtttgct tgataaaatc cgagtaataa aaacacaacc
     9121 attattggtt cgctttactt tacaaacaat tcatgaatcg attaattgtg tagttgcaga
     9181 tattgaaatt atcgataaat tgttaattat ggatgatgga aaatacaata ttgccgtcac
     9241 aggtcatttc aataaacgga atcaattagt cattgaatcg atgcaaatta gaaaccctga
     9301 tcattttacg cgatcaatgg gcatataaat aaaagaagag ctgcaatcct aatgtaggac
     9361 tgcagctctt tttgttttac atagaaacag gaagaaaggg aaaggcctgt ttaggaaggc
     9421 acaagtgcct tctcaattga aaaacctttc tctcactcca accgccaccg ccgttcgaga
     9481 agaaaggaag tgaacgttgc acgttcacta agataagggg tcttgctttg taagacaaaa
     9541 taggaaaagc ttcctctcac caaaaggttc gttcctgttc gctatctctt tattgatttg
     9601 ccagaccggc aacaagttgc cttttatcac caaaaagcga caaggacaag ggtaaatggc
     9661 acgctgcgcg cccttgtcct tgtcgctttt cgttgattca ttctggccaa caaatcaata
     9721 aagaaagaac taacgaaagg aagtaaaacc tttcctaaga ggaggcagaa tcaatcatgc
     9781 gaaagaaatt tgattatttg ggtgttccct tcagcgaatt attcccaaac tatcatgcac
     9841 cacatactgt cgaatgcgat tgtggagaaa gagcgaaatg tatcaaaagc tattgtttgt
     9901 atcaatgtcc aacatgcggg aaaaaatata ccttgtctta tggcgattat attttgattg
     9961 aggagaaagg aaagaaacgc tgatgaaaac acaacacaaa ttattgactg taaaagaagt
    10021 cgttcaaatt ttggtggaca aagaagtcat ttctgaaaaa gtagcagaag ctttacttat
    10081 tccgcggtac tggacgatag aaaccccttt agtagaggat gcaccgacta tgctatttga
    10141 agacctagtg aagattgcag gatgtgaact gcattatcaa gaaaacttgg aaacttatga
    10201 aaacgaatat tggttaacca aattagagaa ctaaaaagga gaaaaaaata tggctcaaaa
    10261 ttactatgac gaatttgtca aattaccttt ggataaaatg gcacaaaaaa tggaggatat
    10321 gacgttccta tacaacgaaa cacgtgttcc aaaaaaacat tataaagaaa aattgtcggt
    10381 agctgtggaa gaaatgattg aatcaggtgt cgaaatgaat cttattgcga cgtactatcg
    10441 aacactggaa gaactgaaaa agcaaaatgc aaaatggttt ttccaagcct tactatgctt
    10501 tgaaataggt gtcaaaccaa gcactattaa accttctgaa taccaggctt tagaactaac
    10561 gtatgcgaaa tttatcgaaa cgaaaaaagc caagactgtt tcaagtgaat ggttagatta
    10621 ttttgaaaat atcaataagt atggcgcata ttacaccatg aaaaaggaag acaacgaaaa
    10681 tgaataaggt gatttatcaa ctaacaacgg attccatatc aacgatttga aagaaaaaaa
    10741 ggtcaataat catttatacc gaaaagtgag aatgtgtgga ataaggacaa aaaaagccta
    10801 gtaactaagg gaatggttct tatttcgcac caaccgcccc cgccgcttag gtggtgcgaa
    10861 ataaacgggc aaagcccgat aacttaagag aaagaaggtg atccatttga aaaagattat
    10921 tcccttattg ttagtactgt ttgttggcga aatacttatg cgagatagtg cagctgtaca
    10981 gttaaacctc gctgtatttt tggtaatact ggtgttttgt ttgatctttt ggcggtttgt
    11041 attagtcctc gtgagtctac tattcaagat gattgcagcc atatttttca tggggttatt
    11101 tcgatgaaag gagagagtac caatgccaat tgcaatagga aataaacggt tacccgtgac
    11161 attagatgaa aagagacaaa aagaattgca gcaactaaag cagaagtacg gcaaaagtga
    11221 atccaggatt atgtgtattg cgttagattt attgattgcc tgtattggac aatatctcta
    11281 ttgtattcga ggaagaaagc tttacgcttg aatgcgataa gttaacccga tatatcgatc
    11341 caaaattcta tgaggataaa aacctggcat gggaactggc tttatagaca gagtgctagt
    11401 gcaagtaaag gaagaaagga agatcaccat gaaatacaat ttattagacc ataagcgaat
    11461 gtgggtagag aaattagagg aagacttaga acagttggaa ttgttaggtc ataataagac
    11521 ttcaacggtg tataaagaag gactaaaacg aacgaaaaaa gcacaaaaag aactagcaac
    11581 actggaaagt agggttcaga aaaaagaagt agacttaaca cacacttacc tttaggagta
    11641 gaaaatggca gacaagagaa aagaaaagat tcaaaaatta ctggcgcttg cggcggatgt
    11701 aaatgatgag gaatcagtga gcgcattagc caaagcccag caattgatga tggactatga
    11761 tcttactgaa gatgagattt tcaattatca tgagcagcaa cggatagaag cagtagaaac
    11821 gcacgtgatc tatcgtggac gtccgcaaaa atggctgtat cgtttattta gaaattaaga
    11881 taaaaaaggc tagttaacag gtttgttgac tggccttttt tgatatgttt gtacatgttt
    11941 tattgtgttt taatttttct cttttttata gcaagctcct tttataataa atattccgaa
    12001 aagtgaagac cattttttat ttattaagac tattattatt agtgagataa aatttgattg
    12061 atcttacaga atattggtga cgattatgac actaaagata ctatttatga aaattttgca
    12121 aaaatgttct gaaaattaca tataattgtt ttataaaaaa gggaggcaat tatatgaaga
    12181 aaaaatttgt tagtattttt tgattttagg aattgtttta ttgagtgtat ctactttagg
    12241 aattacagta gatgctgcaa cttattatgg aaatggtgtt tattgtaata ctcaaaaatg
    12301 ttgggtagat tggagtagag ctcgctctga gattgttgat agaggagtaa aagcttacgt
    12361 taatggtttt acaaaagtgc taggtggagt cggtggaaga taaaaaagaa aaactttttg
    12421 acttaattgc gaatgcatat aattcaaagt catataataa tgtagaagta aaagaaggat
    12481 ttcttcaaga tgctaagaaa atacgagagg ataaaccata tcctgaaatt attatatcag
    12541 tgtacaaaca tttatctaaa ttaaaagctg aggaac
//
LOCUS       DAPBBV010000065        11586 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.067, whole genome shotgun sequence.
ACCESSION   DAPBBV010000065 DAPBBV010000000
VERSION     DAPBBV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.067"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            127..1815
                     /locus_tag="RD486_002515"
     CDS             127..1815
                     /locus_tag="RD486_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664225.1"
                     /translation="MKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRI
                     KGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNI
                     CTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYY
                     AYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFV
                     VVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDI
                     TTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLL
                     QFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVI
                     QSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKA
                     ADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIE
                     ITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1802..3436
                     /locus_tag="RD486_002516"
     CDS             1802..3436
                     /locus_tag="RD486_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664226.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3611..4444
                     /gene="msrA"
                     /locus_tag="RD486_002517"
     CDS             3611..4444
                     /gene="msrA"
                     /locus_tag="RD486_002517"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7664227.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4557..5513
                     /locus_tag="RD486_002518"
     CDS             4557..5513
                     /locus_tag="RD486_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7664228.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            5802..6500
                     /locus_tag="RD486_002519"
     CDS             5802..6500
                     /locus_tag="RD486_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDT7664229.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            6650..7966
                     /locus_tag="RD486_002520"
     CDS             6650..7966
                     /locus_tag="RD486_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7664230.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            7983..9398
                     /locus_tag="RD486_002521"
     CDS             7983..9398
                     /locus_tag="RD486_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7664231.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            9862..10182
                     /locus_tag="RD486_002522"
     CDS             9862..10182
                     /locus_tag="RD486_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7664232.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            10208..10525
                     /locus_tag="RD486_002523"
     CDS             10208..10525
                     /locus_tag="RD486_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7664233.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            10554..>11586
                     /locus_tag="RD486_002524"
     CDS             10554..>11586
                     /locus_tag="RD486_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7664234.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVL"
BASE COUNT         3873 a         1820 c         2287 g         3606 t
ORIGIN      
        1 gtaataaaaa ttgattcttt tctagtatat catactagtg ctatgaaaaa tttaacgcaa
       61 aacttattaa aaaaagacaa ttctagtata ctgaaaatag aattaaaaaa ggagaacaac
      121 aaatctatga aaataagtaa aaaagcattt cttttagtag ttcttatctt acttagtact
      181 ttatattcag taaattttat gagaaatgct caagaaattt atacaacagg tgatttatct
      241 tttcatcttt cacgaatcaa agggttatct tctatttttg aagggccaat caactataca
      301 acatttaaca attatggaga tggactgaac tatttttatc cttttcttac aataattcct
      361 gcagtcgttt tttatggaat ttcaaataac ttaatattaa gttatgttct atatatttgg
      421 ttattaaata tttgtacgat tctgattagt ttttattatg gagaaaagtt ttttaaaaag
      481 atagatgctg cttttttatt tagttgttta tatacttttg caacttatcg aacagttgat
      541 atctattatc gatccgcaat tgcagaagca atcgctctta cgattatccc agctgtttta
      601 tattatgctt atggattgat attcaataga gaaaaaaaag tcatcgcttt atctgtcagt
      661 ataagtctac ttgtgtatac tcatgtctta actacactat tgtgtagtgc attgattgct
      721 tgtatgatta tagttcgttt gtttttaagc aagcaaataa aaaacgatat aaaatttgtg
      781 gtcgtgaatt tagtaaaggc tgtttttttg acttgtgcat taactagcta tttttggtat
      841 cctatgttgc agcagatgaa ttatcaagaa atacacagtc ccttcaaaac agatttgcag
      901 ctagaagcac tttctatttc agatagtatc attcaagcgt taaataacga tattacaaca
      961 tacactatgg ggttattagg attggttgcg ttgatttttc ctttattcat actgaaagaa
     1021 atggagaaaa aagaaaaaat catctatgtt ggcgtagttt ctacatgggt atgcgtaact
     1081 aatttatttc catggttttt gtttcaaaaa acaccgataa gcttactcca gtttccttgg
     1141 cgtatcttag gtatccaaat ctttttttct tcaatgatca taacgcttgt ttttatgaaa
     1201 aagactatga ataaaaaata ttcatggtta atcattggcg ctactgtggt gtttctactc
     1261 gtcacgtcta tagcagcaaa agaaaattac gcaaaagtta tccaatcaaa acacggtcat
     1321 attgttatca atgaagaaac actcccacgt tatacaacat cagatatggg aggattatac
     1381 gattacgccc caacagaagc gataaaagaa aggcctcact tagaaaaaca tgaagtaaaa
     1441 gtaggagaat cgtgggaaaa agggaagtat aaagctgcag ataataacat tacttacaca
     1501 gtggcaagca acaaaaagca aaaagtgaca gtaccagtat atgcttattt aggtacacag
     1561 gtaaaagtaa acggtaaagt cgtaaatgac tcttataaaa aacatggctt agtgaatgtg
     1621 gatgtaaatg ctggagaaaa taagatagaa attacaacaa aatatactcc aactgctctc
     1681 atggctttat ggatcagtat tctgacttat tgtttagtgg tgtattcaag ttttaaacga
     1741 tttgcaccta ataagttgaa agattctcga tatgtgacta aaaaggagat aaacaagaag
     1801 aatgaaaata aataaaaaag tagtaatatt gagtggatta attatagtta gtagtatata
     1861 ttctttcatc tttttcaaaa atacacagag tatttatacc actggagatc tttcttttca
     1921 cttatctcga atcaaggggt tatcgactat ttttaccagt ccgattaatt atgagacatt
     1981 caattatact ggatatggtg taaattattt ttatcccttt ctgacttttt ttccagctgt
     2041 aatgttatat tggatgacaa aaaatttgat tgtaagctat attatttacg tttggttatt
     2101 gaacttgtgt acaacactcg tagcttatca ttatggcgag cggtttttaa aacaaaaaaa
     2161 agcggcattt ttatttagtt gtctctatat tttctctgct tatcggacag tagacatcta
     2221 ctatcgttcc gcaattgccg aagctatcgc aataacactt gttatccctg tattatttta
     2281 tgcttatcaa atcatctctg gaaaagaaga aaagtatccg tctgtaaagc tagcattgag
     2341 tatgagtttg ctagtgtaca gccatgtact atcaacatta atgagtacag cattaattat
     2401 catttttatt tttattcgtt tggtttctaa aggtttcaag aatgcagatt ttattgctat
     2461 atttaaaaaa ttatttagtg cggcaggaat gacattggtt ctgacgagtg ctttttggta
     2521 tccgatgttt gaacaaatgc tctaccaaaa aatcaacaaa cctagcgtga caaatttata
     2581 tgctcatgca tctaatgtgt tcgatagtct gactgaagct atgaacaacg acttaactac
     2641 ttactcaatg ggactagttg gtctgttatc tttatgtatt cccctgattt tatttaaaaa
     2701 attaacaaac atagaaaaaa agatttatta tggtacgtgt ttgacttggc tagctacaac
     2761 tagtttggtg ccatggtatc ttctgcaaaa tacgccagcc aaattgttac aatttccttg
     2821 gcggatctta agcttgcaaa taatattctc ttctctgata ttaacgatga tatttttcaa
     2881 aaatagaaga tacaataaga caagagaact attttattta tttatgactg ttttgttatt
     2941 aatcacttta actgtttcta gtaaaaaaaa tttcaatcaa aaaataattt ctcagccggg
     3001 acatattgtt gtaaacaaag aaacagtaga ggcgtatacc actaaaggaa tggattattt
     3061 tttatatgat tattctccta tcgcttcatt ggagaataag gagcatataa taaaacacga
     3121 agcaaagatt ggcagtcaat gggtaaacct tccttataaa acaactggta gttctatcat
     3181 atatagagta actaatgaga agagccaagt aatcacactt cctgtatatg cttatttagg
     3241 aacgaatgta gaaataaatc atcaacctgt aaaggagcag gtgaatgcta atggattggt
     3301 acaaataagc ggagtcaaag gagttgctga tattaaagta agcacaagtt atacagtaac
     3361 gactattatt tcttatcttg ttacattaac tgcatattta tgtttatttt ttaaaatagt
     3421 tttccataaa aggtaaatta acttttcatt tataaaataa attgattaaa aaggagaatc
     3481 tgtcgataag gattctctct tttttatacg aaaaatctgt agggggatga agtaatcgct
     3541 tatttcctca ctttatgata aattacagct aaagtcacta gcttgtcttc ttcggaaagg
     3601 aggagaatct atggatgagg aacaaatatt cattcaaaca ctttataatc tgattttgaa
     3661 tccgaataca cgagattggg aacgaaaagt attgattcag acaaagaatg acataagaga
     3721 aaatatatcc gttaaagaac agttatcaaa actagaagca acactacgtc cattagctat
     3781 ccgaatgaat ctgacgcctg atgtaatgga cttttattta ttgattacgg aaggatttga
     3841 taaggagcaa aaatatgact tttccaagca tgccatgcaa gatgctgact atcaagaacg
     3901 tgcagtattt gcagggggat gtttctggtg tatggtcgag ccgtttgaat cgaaaaaagg
     3961 gatcctatct gttttgtcag gatacacggg cggacatgtt gaaaaaccaa attatgatca
     4021 agtaagtggt ggttacacag gtcatgtgga agctgtggag atcatttatg acacaagaga
     4081 aataagttat agcgagttgc tgacaatcta ttggcaaatt actgatccca cagatacatt
     4141 tggacaattt caagatagag ggaagcaata tcgtccagtg attttttatc aagtcgaacg
     4201 acaaaaagaa ttagcggaac aatcaaaaca gaaactagac agttcaggaa ctttccacca
     4261 accaatcgtc acaaaaatcg aaccagccgg tacgttttgg ccagcagaaa actatcatca
     4321 gcaattttac aaaaaacaac cgaaacgtta taaaaaaatc cagcaagcac gtaatcaatt
     4381 tctgatctat caacgagtaa aaaacaaatg gcaaaaaaat atacgaaaaa atcattttga
     4441 ttaactcctt ttctttaaaa tgtagtaaac taaaaataga aaaaagaaag cgttttaaaa
     4501 agatttgatg aggaggagaa aaattgtata ttgcagatag tgcacgttat gaaaaaatgg
     4561 aatatcgtaa atccggtcat tcaggtttga aattaccgat tttatctctc ggattatggc
     4621 aaaattttgg tgattatgat cctatccata atcaaagaga gattttaaga ggcgcattcg
     4681 acatgggaat tacccatttc gaccttgcga ataattatgg aggccctgct ggagctgcag
     4741 agaaaaactt tgggcgtatt tttagagaag attttcaagc ctaccgtgat gaactgatta
     4801 tttctagcaa agcaggttat catatgtggg aagggccata tggggaatgg ggctctcgta
     4861 aatccatcat ttcaagttgt gaccaaagtc tccaaagaat ggggctagat tatgttgaca
     4921 tcttctatca tcatcgccca gaccctgata cacctttgga agaaacagca gaagctttga
     4981 tgcaacttgt aagacaagga aaagcattat atattggtat atccaactat aatggagaag
     5041 atacaaaaaa aatgactgaa attttaaaaa gaaaggaagc accgttcatt attcatcaga
     5101 tgcgctacaa tatgttttct cgtgcactac tagaagacga tctatctcca gtattagaag
     5161 aagaagggct aggggcaatc acgttcagtc cgcttgctca agggttgctg acaaatcgtt
     5221 atctacatgg tattcctgaa gattctagag cacatcgtaa ggaaatacca ttcctttcag
     5281 aagaacaagt tggatcaact ctggaaaaaa tcaaagcact gcaaacaatc gccgtatcac
     5341 gaggacaatc attagcgcaa atggcccttg catggaattt gcgacaaaaa tctgttacaa
     5401 gtgtactggt cggagcaagt cggttaagtc agttacaaga aagtgttcga atgatggata
     5461 atttagattt ctcaccagaa gaagaattga gaatcgacca aattctagaa tagaaacgat
     5521 gtaatcaaac tttttatcca tatattaaaa aaaacaaaag atgacatcaa gaatcgaatg
     5581 aagatcgtct gttattgaac atcatatttt ttgtcgttca aaataaaaat gatcgaaggc
     5641 taggagtgaa ttttatccta gtctttttta tggtaaatat cttcttcgtt tgtatgtcta
     5701 tgaacggatt aatcaatttt gtatacaaaa aatcatcaga tgattcaaac gtgttataat
     5761 aattacgaaa aaatacatca gatgaaaagg aggtatgtgg tttggaagaa aataaaaccc
     5821 tagtagaagt aactactgac aagatcctta gatatttaaa ggaaatgcag ttgcaagtag
     5881 gagataaact gccgaatgaa tatgaattgt ccgattattt agaggtgggg cgaagcacgg
     5941 tgcgagaagc tgtgcgggct ctagcttcca ggaatatcct tgaagttcgg caaggagcgg
     6001 ggacatttgt cagtgataag cgagggattg ccaatgaccc actcggtttt tctttgattg
     6061 aagatcagga tcggatgata cgagacttat ttgaactgag atatttattg gagcctaaga
     6121 tggcaggttt ggcagcggaa tatgcaacga agaatcaaat cgtccaaatg aaaaaattaa
     6181 cgcaaaagat tgaaacttct tttcgagaag gcacacaaga acatgttcaa ttagacatcg
     6241 attttcatac gatgattgca gaagctagcg gaaacgtagc cttgctgcat attatcccaa
     6301 tcattaatga atcaattgct ttgtttaata aaaattatga tatccagcat ctgaaaatcg
     6361 agacgatcga tattcataca gagatcgttc aggccatcga aaggcggaat gcacttgctg
     6421 cgtttgatgc aatgactgtc catatggcaa taaatcggag agaattacag aaaataatag
     6481 gagaaaaaga aactaattga cagttcatct gatgtatttt atgataaata catcagatga
     6541 atttttgttt tatatttggt aaaaaagagg agtaaatagt ttctgttcat cgaaatgtaa
     6601 gcgctgacta atagacaaaa agagatgacg tcaaggagaa gaagcaggaa tgaggggatc
     6661 tggaatgagt tttatggata aattagccaa tgttttaggg aacgtggcaa cgagaatcaa
     6721 taatttaagg tatatcatgg tgataaaaaa cgcatttgct gcattgattc cggtaattat
     6781 tacgggtgct tttggcacat tgttttcagc aatggtcttt gactcggaaa atggcttagc
     6841 acagataagt ttcttgcgtt ttttagaaga attaaagcct atcgcatctg ccatcagcta
     6901 tgtcacacta agtttcttga ccatctatgc tgtttttctg atagggatcg aattagccaa
     6961 gctgaataaa gtggatggtg tattccctgg tatcatcgca gtgatgtctt atttatctgt
     7021 taatccaact gtttatgaat tagtgaatga aaatcagact gttatagtag aaaacgtatt
     7081 ggctaaacaa tatacagata cgaaagggtt atttttggga atgttggtct ccatcctttc
     7141 tattgaactt tattgctggt tgaggaaaca gaagaaacta cagctgagaa tgcctgatac
     7201 cgtgccaacg aatgtttctg ctagtttttc tgctttattc ccgacgattc tgactgtatc
     7261 gggtatcgcg gctgcgggat ttatcatcaa agaacttaca ggaatgtacc tttatgatat
     7321 catttacaat gtcgtacaac gcccattaga aggtgtcgta caagggttac cgggtatttt
     7381 gctattgatg tttattgcgc aagtcttttg ggtgattggt atccatggaa atcaaatggt
     7441 gaagccgata cgggaaccgt tgcttttagc ggcaattgct gtaaatacgg aagcttttga
     7501 agctggaaaa gaagtaccga acattattac tatgccattt tgggatatgt atatgagtat
     7561 gggcgggtct ggagtcacga tcggtttact gattgcagta ttgttagttg gaaaacggga
     7621 agatatgaaa caaatcacca agttatccct tgctcctggg atcttcaaca tcaatgaacc
     7681 agttattttt ggtatgccga tcatgctgaa tccaatttta gctattccgt ttatcttaac
     7741 gcctcttatc actggaacga ttggttattt tgcaaccgct ttaggatttg cggcgaaagc
     7801 agttgtaatg gtcccttggc caatgccgcc gatcgtcaat gcttatctgg caacagcagg
     7861 aaatatcggt gcagttatta cgcaacttgt ttgtattatt gtttctattt tgatctatct
     7921 gccatttgta aaagtagcaa atcgtgtgga aaatgatggg atctaaaaaa caggaggaaa
     7981 tcatgaaaat tactattcca aaaaatttta ttcttggtgc tgcatcttct gcttggcaaa
     8041 cggaaggttg gaaaggaaaa aaagaaggac aggattcgtt tatagatagc tggtataaaa
     8101 atgaacattt tgtttggcat aatgggtatg gcccagccgt agcaactaat tttatggaac
     8161 aataccagca ggatgtggat ctgatgaaat ccatccatct gacacattat cggacttcta
     8221 tcaattgggc tcgttttttt actgattatg agaactgtat agtagatgaa gaatatgctc
     8281 agcatataag tgaaatgatc gactctttga tcgaagcaga cgtagaaccg atgatttgtt
     8341 tggaacatta tgaagtccca gcttttcttt tggaaaaata tgatggctgg tcttcaagaa
     8401 aagtagttga tttttatgct aagtatgctc aaattgcctt tgatcgttac ggtgataggg
     8461 taaaaaactg gtttacattc aacgaaccaa tcgttcccca aacgcgttgc tatttggatg
     8521 ctgttcgctg gccgcatgaa caaaacacaa aaaagtggat gatgtggaat tatcataaag
     8581 ttttagcaac ggctaaagca gtagagattt accgcagcgg aaattatggt ggaaggattg
     8641 gctgtatttt aaatcctgaa atggtctatg ctcgatccaa ttctccagaa gaccaaaaag
     8701 ctgcttatat gtatgatttg ttttataatc gagtattttt tgatccgatg gtaaaaggat
     8761 actacacaga agagttcctg gagttgtgtc aaaaacaatc gatttatttc gatcctgcaa
     8821 cagaggattt agaaacgatt cagcatcata cagtagattt ccttggaatc aatcaatatt
     8881 atcctaaacg cgttcgcgcc cctcgttatc aatggaatga agagacacct ttccatcctg
     8941 aacgatatta tgaagtcttt gatttacctg ggaagaaaat gaataattcc aggggatggg
     9001 aaatctatcc gaaaatcatg tatgatatag ccatgtatct aaaagaaaat tatcataata
     9061 tcccttggct gataacagaa aacggtatgg gaagagaata tgaagaacag tatatggatg
     9121 agaaaggaat cgtgcaagat gattaccgta tcgaatttat cggacagcat ttgcattact
     9181 tgatcaaagc aacagaagaa ggcgcaaatt gcgaaggcta tatgttatgg gcattcactg
     9241 actgtgtgtc accaatgaat gcatttaaga atcgatatgg attagttcga atcgaattga
     9301 acgatgaacg aagcagaaca ttgaaaaaat ctgcttcgtg gtatcagact ttgattgata
     9361 agagagaatt ggatttgcct gacgaaatct ataaataaat agaagttttt tgtagatgtt
     9421 cattgtattt actggttatt tgaaataaaa gaggttgtga atccagcgtt ttgagctaat
     9481 acccagggtc agctgattga acaccgttta ttgagaggtt gtgaaaaagc tgtcctgcat
     9541 caagtaataa gaatagcaaa gtaaaaacaa catcttatgt ttttaacttg gttggactta
     9601 ttaccgcaga tgcaagcttt tgaataccgt ttatttgaaa aaagttgtga caagttttgt
     9661 gtcacaactt tttttgtgca cgttaaaaga aaaaaggtaa taaaaattaa tttgtgtgtt
     9721 tagtgtgcgc tttctttttt agtgtgtatg caacttggta tagaccttaa atgtgatgat
     9781 atcaactttt taaagcgctt ttaaagttgg cacgctactt gcttatatac aagtgtaagt
     9841 atagaaagga acgtgtttaa aatggaaaag aaaacaatca tgcttgtatg ttcagctgga
     9901 atgagtacaa gtctcctagt cacaaaaatg caaaaggcag cagaagcaaa aggaatggaa
     9961 gcagacatct ttgctgtatc tgcttcagat gcggataatc aactagaatc taaaaatgta
    10021 gacgttttac ttttaggacc gcaagtacgc tttatgcaaa atcaatttgc tgaaaagcta
    10081 gcacctaaag gcattccttt agatgtaatc aatatggctg actatggcat gatgaatggt
    10141 gaaaaagtac tcgaccaagc agaaaaacta ataaacaaat aataaaaatt atcggaggat
    10201 acaataaatg gaagatcaaa aaaatctaga agccatcatg ggtctgatca tgtttggcgg
    10261 aaatgcaaaa agcgatgcaa tggaagcgat tgctgctgcg aaaaaaggtg atttcacttt
    10321 agcagatgaa aaaatcaaag atgcagagga atctttagtc caagcacatc actctcaaac
    10381 agagatgctg acacaagaag cacaaggaaa tcacgttgaa gtcacgcttt tgacggtcca
    10441 cagtcaagat catctgatga catctatagc ttttacagat ttagcaaaag agatcattga
    10501 tctgtatcgt cgattgaacg cgtaatctac agtaaagaaa agagggaaga tttatggata
    10561 aatttgttgc atttatggag aaacatttta tacctgtagc atcaaaaatt ggtgcacaac
    10621 ggcatttagt tgcgattcgg gactcattta tggtgagtat gccgttaatg atcttaggag
    10681 cattagcagt aatgatcaat aacttaccga ttcccgggtt ccaagaattg atgaactcaa
    10741 tttttggtgg tgaatcatgg aaaggattcg gggctgctgc ttggaacggt acatttgcca
    10801 ttctttctgt cttgattgct ttcttgcttg cttatcattt agctaacggc taccgaaaag
    10861 acggtgtttc cgcaggtgtg atttctttag gctctttctt cgctttaggc ggagcattag
    10921 gtatgagctc aaacggtttg tttattgcta ttattgttgg gattatttca acagaaatct
    10981 ttgtacgttt aagcggaaat gaaaaattga tcatcaaaat gcctgatggt gtgccaccgg
    11041 cagttgcaaa agcatttgct tcattactac cagcaatgat cactatctct gcgtttgctt
    11101 tagttgctgc aatttttgct gcattcggtg ttgatgatat cgtaggttct ttctatacag
    11161 tggtccaaga accatttatg ggacttgcaa actcttatcc atctgcctta ctgcttgcat
    11221 ttatcacacc attcttatgg ttctttggtt tacacggagc gaatatggtc gatcctttga
    11281 tgcaaacaat caatgcgcca gccattgaag caaacgttaa tgcaatcgca gctggacata
    11341 gcgcaccgtt tatcgtgaac aaacctttct ttgacagctt tgtcaactta ggaggaacag
    11401 gtgcaacttt aggtttactg ttagctattt atttagtagg acgtaaaaac aaaccatata
    11461 tggttgtaac aaacttgtcg attgcgccag gtgtcttcaa tattaatgaa ccaacgatgt
    11521 ttgggttacc tatcgtgttg aacccgatca tgttcattcc atttattttg acaccaatgg
    11581 tcttag
//
LOCUS       DAPBBV010000066        10848 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.068, whole genome shotgun sequence.
ACCESSION   DAPBBV010000066 DAPBBV010000000
VERSION     DAPBBV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.068"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(123..1907)
                     /gene="pyk"
                     /locus_tag="RD486_002525"
     CDS             complement(123..1907)
                     /gene="pyk"
                     /locus_tag="RD486_002525"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDT7664235.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(1981..2943)
                     /gene="pfkA"
                     /locus_tag="RD486_002526"
     CDS             complement(1981..2943)
                     /gene="pfkA"
                     /locus_tag="RD486_002526"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDT7664236.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(3111..6425)
                     /gene="dnaE"
                     /locus_tag="RD486_002527"
     CDS             complement(3111..6425)
                     /gene="dnaE"
                     /locus_tag="RD486_002527"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDT7664237.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            6656..6841
                     /locus_tag="RD486_002528"
     CDS             6656..6841
                     /locus_tag="RD486_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HDT7664238.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(6903..8099)
                     /locus_tag="RD486_002529"
     CDS             complement(6903..8099)
                     /locus_tag="RD486_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7664239.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(8269..9705)
                     /locus_tag="RD486_002530"
     CDS             complement(8269..9705)
                     /locus_tag="RD486_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDT7664240.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            9998..10807
                     /locus_tag="RD486_002531"
     CDS             9998..10807
                     /locus_tag="RD486_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7664241.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3243 a         2269 c         1928 g         3408 t
ORIGIN      
        1 atttttaacc aaataaacag aacagaaaga ggttttcttc tttctgttct gtccaaatta
       61 ttctaagatt tctctttacc aacatcattt gacaaagagc ctttattttt tattaagcta
      121 aattagatag ctgttgtttc gccacggtaa acgatgccgc gacgtgaatc aacggtaatc
      181 aattcacctt ctgtaattgt tgttgttgcg cctttagcac caacgattac aggaatatct
      241 tgtgcaattc ctacaactgc agcgtgagaa gtcaatccgc cttcttcaac gataacagca
      301 gctgcttttt cgattgcagg catatattct ttgtcagttg atggtacaac tagaaccatt
      361 ccgtcttttg ctttttttac agcttcttca gcagatgaag caataactgc atttgcaacg
      421 acagattttt gtccaacgcc ttgagcttct aataatttag aaccaatcat ttgaattttc
      481 atcacgttag ttgttccgcg ttcaccaact ggtacaccag cagtgatcaa gattaaatcg
      541 ccttctgatg cgaaacctaa ttcaacagct tttttagctg ctagttcaaa catttcatca
      601 gttgttgatg gtttttcagc aactgttggg taaacgcccc agtttaacat caaaccacgt
      661 tttgtgcgtt cgtcaaaagt aacagccaag atatctgcat ctggacgata ttttgaaatc
      721 atttttgcag tgtatcctga ttcagttgca gcaacgattg ttttcacgcc tagatttttt
      781 gcagcacgag ctacagataa accgattgtt tcagttacat ctgttttatc gaattcgttc
      841 aattggaatg tacctaattc tgataatgca ttttcagctt cttggtcgat acgtgccatt
      901 gttgaaacag cttcaactgg gtagtccccg tttgcagatt caccagatag cattgttgca
      961 tctgtgccat caaatacagc gttagcaacg tcagaagctt ccgcacgtgt tggacgtggg
     1021 ttttcttgca ttgattctaa catttgtgta gcagtgataa ctgggatacc agcagcatta
     1081 cattttttga taatgcgttt ttgaaccatt ggtactagtt cagctgggat ttcaacaccc
     1141 atatctccgc gggcaatcat aacaccgtca gaaactttga tgatttcgtc aatgttgtcg
     1201 ataccttctt gagattcgat tttagggaag atttgaacat gagtcatgtc tttttcttct
     1261 aagatttcgc ggatatctag aacgtcttgt gctttacgta caaaacttgc agcgataaag
     1321 tcgatatcgt tgtctaaacc aaaacgaata tcgtcagcat cttttggagt aatacctggc
     1381 aaactaatag aaacgcctgg tgcatttacc cctttacgtg atcctagcat acctgcattt
     1441 ttaacttcta cgactaattc acggtttgct tcgtcttttt caatgatttg catatcgatc
     1501 aaaccatcat caaataaaat gtgtccgcca acgtgaacat cgtcaaataa tcctgggtaa
     1561 gtaaccgcga ttttttcttt tgaacctaca tgttcaggat ccatagagat gcgtgtttga
     1621 tctcctactt caaatttgat gtatcctgca cgaccaaaat cagcttctgt tgtgccttga
     1681 acagttgtac ggatttcagc tccttttgta tctaaaagaa taccgacatc ttttcctgtc
     1741 tttttaactg cttcacggac catagtcata cgtgataatt gttcttcatg gtcaccatga
     1801 gaaaaattaa agcggaagac atttgcccca gattcaatca attgagaaat aatttctact
     1861 gagttacttg ctggtcctaa tgtactaacg attttggttt ttttcattta aaaaactctc
     1921 ccattcaatt ttgtttattt aaagctgtac acagcttaaa tagcttggtt tctttcactc
     1981 ttaaaatgaa agtgaattat ttagatcata tagtgataag tctggtttat gtttgttgtt
     2041 ttcaagtgta tcaatgatgt cagacgcaac gatttcgttg tcatggatac cgacacataa
     2101 tccacctttt ccttcttgaa gcaattcgac agcgtaagca ccgaatttac ttgccaacac
     2161 gcggtcgcgt gcgcttggtg ctccaccacg gacaacgtgt cccaagatag atacacgtgt
     2221 atgatagtca ccaaattctg aaagtttctc agcgaattca tttccgccca ttacaccttc
     2281 agccaagatg atcaagcaat gtttcttccc gcgatcgcgg ccttcttgga tttttttagc
     2341 aactgaagcc atatcaaaat catgttctgg gatgatgatt tcatccgctc cgccagccac
     2401 acctgaccat aaagcgatgt ctcctgcatt gcgtcccatt acttcgataa cgaatgtacg
     2461 aacatgagaa gtcgctgtgt cacgaatacg gtcaattgat tctagtactg tattgattgc
     2521 tgtatcaaaa ccgattgtga aatcagtccc aggaatatca ttatcgattg ttccaggaat
     2581 acctactgct gggaaaccgc gttttgtcaa agccattgcg ccatgataag agccgtctcc
     2641 tccgataacc actagacctt cgattccgaa ttttttcaat tgttcgattc cttttaattg
     2701 accttcttca gttgcaaatt ctggataacg tgcagaatac aagaatgtac caccacgttg
     2761 gatcttgtca cctacatctg ccacatcaag acgacgaata tctccagcaa ctaaaccggc
     2821 aaaaccataa ttgatcccgt atacttccag tccttcgtaa atacctttac gaacaacggc
     2881 acgaacagct gcattcattc caggtgcgtc tccgccactg gtcaaaattc cgatgcgttt
     2941 cataataaac attcacctca ttaaaatact ttatcctaag tatgacttag gtttacaacc
     3001 atttttgcgt taaccacgac taacattcta acattatttt tctcacttgt cttgatttac
     3061 ggataaaaaa atgaaaaaaa atgaaagcaa gtagtatttt ttaccgtaag ttatttgaaa
     3121 accacattat cttcgccaag cagataaata agttgccgct ttatactctt gctgtcatcc
     3181 acccaataag catctgacag aactactttt cgttgcgttt tttcgtgata cataactact
     3241 ggtatatatc ctgggtgttt ctgaaaaatc acttgtaatt gtttcattat ctcgggatct
     3301 tcccgttctt ctgtaatacg caaatagcaa gtttgtgaag gatactgggc ttctaactgg
     3361 ttaggatcag caaagctttc tccaattagt tgcagttcct gattatattt gctgatttcg
     3421 ctccgccctt gaacaaagat cactcgatca acggcaaaca aattacgata tttacgataa
     3481 agagttggaa aaactgtgac agaaatttct ccactactgt cggttccttc aacaaaggcc
     3541 atcagttctc ctttttttgt ccgaatttct ctaacttcct tgatcatcac taataaattg
     3601 actggttgat tagggacgat atctgtaatc agctgaactt gtttagctaa acgaagacga
     3661 tcaaaccctt ctgcaggatg acctgacaaa taaataccta agtactcctc ttccagcttc
     3721 aagcgttctt ctagtgtata gtcagcgact tcttcttctt ttaatgccat gattcccagc
     3781 aagtcaagac ttccaccact gtaaacgata ttttggattt ttccttcgag atcaagcatc
     3841 aattgtttcc tgttaggaga taattcatca aaaactccta ctgctgtcag tgattgcagt
     3901 aactctaatt tcagccaacg cttatcgatc cgtatgagga attgatccac tgactggaac
     3961 gggccatttt gttttctttc gtttaatata tcttctacaa aatcacgccg aatacctttt
     4021 atcgctgtca gtccgaatct gatttcttcc ttattgacca actcaaaact ggaattactt
     4081 tgattaatgg acggcgagga aagtttgagt ttatttttac gtgcttctgc aatatattct
     4141 ttcaattttg atgtgttatg ccgaacagaa ttcatcaggc tggtaaagaa agcacctgga
     4201 tgatgggctt ttagatacgc catttggaat cccacgaatg aataagcaaa tgcatgtgac
     4261 cgattgaatc catagtttgc aaatttttcg atatattcat atacggtcgc tgctgttttt
     4321 tccgaatatc cctgttgtaa tgctcctgat acaaaatgcg acttttcttc atctaatacg
     4381 tcttttttct ttttactcac tgcccgtcgc agaatatctg actgccctaa tgtaaatcca
     4441 gccatagtcg aggcgatctg catgatttgt tcctgataga cgatcactcc atatgtgttt
     4501 ttcaaaatcg ggatcagtga atcatctggg tagcgaatgg cttcttttcc tttcttcctg
     4561 gcaatgaagg tatctatatt ttgcataggg cctggtcgat acaatgcatt gactgcggca
     4621 atatcttcga tgttttctgg atctaatctt cgtaaaacgt tccggatacc agcagattca
     4681 aattgaaata ctcctgaggt ttcgcctcgt tgaaacaaga gcagcgtttt tgcatcattt
     4741 agcgggatct cttttaatcg gatctcatac ccttctactc gcttaacagc tttcaaagta
     4801 aaatcaataa tcgataagtt gcgtagtcct aaaaagtcca ttttcaaaag accgattgct
     4861 tctacctcat tcatcgtata ctgggtcaga aaagcttcat cagaaccgcg ttggagcgga
     4921 actagttcaa gtagattctt atcgctgata actacacctg ctgcgtgagt cgaaacatgt
     4981 cttggcaatc cttctaaaat cactgcagtt ttgaataaaa gttggttttt ttcgcttgcc
     5041 tgaactaatt ctactaattg atgcgaagtt ttataagctt gggtcaatgt gattttcaat
     5101 tgattgggta ttgcttttga ccagcggttt gcttcacttt gcgataaacc aaacactcta
     5161 gctgcatctc taagaaccat ttttgctgcc attgtgccaa atgttgcgat ttgtgccata
     5221 tgatattgtc catacttttc tcgaacataa ttcaatactt cttcacgtcg attgtcagga
     5281 atatccaaat cgatatctgg catcgtaaag cgttcggggt ttaaaaagcg ttcgaacagc
     5341 aaatcatatt ctaatggatc cacatctgtg atttctaaca cataggctac taatgaaccc
     5401 gcagcagaac cacgacctgc accggtaacg attttgtttc tatgagcaaa agccattaca
     5461 tcccatacga tcaagaaata atcatcgaat cccatttgat ggatgacaga taactcgtag
     5521 tccaaacgtt cttggtattc ctttgtatag tcagtgattc ggcgttccac ttgcgaatag
     5581 cataactctc ttaaatattc tccagcttgt tttccattag gaactggata atgcggaagt
     5641 aatttctgat ggaactggaa ttcaaatgaa atcgattcag ctaaacgctg ggcgcctatt
     5701 acagcttggg aaagacccgc tttttcgaat cgtttgatca tttcttgttc tgaaagaaga
     5761 tagacatttg ctgttagtgg taaagatgca gataaatttt ctaaaggtat ttggcttccc
     5821 tctttgatat gtttcatcac ttcaagtgca aaaagttctt cttgttgtaa actagcgatg
     5881 ggatgtaatg cacaaagcga ataattttct tttatcacat actgatacca ttcaggcaat
     5941 tgatcaggcg tgttttctgt caagccgata taaaaatttc tagtaaaaac attttcaagt
     6001 aaaaactgcc aatgaccgaa aaagttatcc tctttattga aagcctcaga aacagaatga
     6061 tttgccggaa caacaaacgc tagatggtcg gtttctgtca tttctgcaag ttccaatttt
     6121 tcttggatca tttttcggct ggaaagtttc atcagctgct gataacctat ttcatctttt
     6181 gcgtacgcaa gcaagccata atttttttct tcataagtat aactaagatg taatccaatg
     6241 attggctgta ctccttcttc tacacaaata cgatagaatt caggtgcacc gtataagaca
     6301 tctttatccg ttatggctaa tgaagtgtag ccttgttttt ttgcttcttg tacatattct
     6361 cgaatacgta tcgtactttg taaaagagaa taagaagtaa ttgtataaag ttgtgggaaa
     6421 aacatcttgc attccgcctt ttttttcgtt aaaattcact agcgttaaaa ggtttgatcc
     6481 ttttactttc attaagatag caggcgctga agttgattat tccacttcat ttgcttgctt
     6541 gtaatctgta ggaatgagtt ctttcgcaag aactcaaatt ttattgagat ttggtctcgt
     6601 ttctttacat tcaaagaaaa tctggtaaaa ttaagataga aaagaggtgt tctttatgcg
     6661 atatatcgtt acattattct gggctgtcgt tctaggtcaa gtagtcggtt atattggtgc
     6721 tgcattaaca agcggaacat atgattttac tttgacaaca atcatttcat tcattgcggg
     6781 tgtcattatc cttttgattg gtgcagttgc gccaagaaaa gaaacctctg cccattcgta
     6841 aaaaaacagc caagagcttg agatttctca agctcttttt tattttctac tcctcaccac
     6901 cattataatc tgctgcgaag aactttacga aagttgaata aagaaagaag aatatttgac
     6961 agaacaaaca aacttgtcac aataaaaaca gcactgtaat tataagcatg cgcgactgtc
     7021 gatcctagca tgggacctaa aacttgtcca aagttgctaa acatctgatt gtagctatag
     7081 attcggctga ctccttcttg aggcgtaatc ttactgatca gtgtattgac agaaggcatc
     7141 aaagcgccag ttgaaaagcc taaaataaag cgaagtatac ctaattggag cggtgtagtg
     7201 acgaatgcca taggtaaata acagcaaaat gataaaatga gtcctccaat tagaactttt
     7261 tgattcccaa tcttatcccc tagttttcct agtttcggtg aagaaaagac agcggaaaca
     7321 ccagctatcg aaacaatcaa gccgctgaca aaaaggatat tttctgtact tccgctcaat
     7381 tcacgaatat ataaggtcaa aatagggctg atcgtagtga ttcctatctg taaaatcaag
     7441 gtcgtaatga aaagaccgat caaaatagag agatgatcca tttttgaaaa aatttctttg
     7501 gtgcttatca gatctttttt ctcgattgga tggaaatctt ctttgactaa gaaaatggtc
     7561 aataccgttg tgatcatcaa caaagcccct gtgatcaaga atacattttc cataccaaac
     7621 cactgagcca gtgcaccgcc cattgaaggt ccgatcagat ttccagcaat cgctccggta
     7681 gacaatgttc ctaacgccca tccgctcttt tctctaggtg cctgtgaagc aatcatcgct
     7741 gtggcatttg gaatatatcc agacaaaatc ccattccaaa accgcatgat caaaagccaa
     7801 tacgcgtttg gtacaaaagc caaagatccc attgttaatg tcatccctgc tgctgcacgg
     7861 atcatcatga gttttcggcc ttttcgatca gctagatttc cccagattgg tgcaaccacg
     7921 gcagatgcaa aagcagtcac agagattgct agtcccgaaa acaattcgat ttgatctttt
     7981 ggtgttccta gttgctcaac ataaactggt atgaatggca taactaaact aatacttgca
     8041 ccagtgaaaa aacagccaat ccacgcaatc actaaatttt ttctccaatt aatctccatc
     8101 tatcatccct ctttcgtctc ttttatcata cctattttcg aataaacaag caacgatctc
     8161 gccagtaaaa agagaaaaat cccgcaaagg tcattttata tgtaacgttc tttttatgta
     8221 aaacaaaaag agatcagaac aaatactgtt ccaatccctt ctctttagtt aaattgttgc
     8281 tagaatgatg aagttgataa tgaataaaat atcaacgatc cacaaagcaa cagaaacttg
     8341 attgtatttt cctttgatta ctttcacaat tgtatagaaa ataaatcctg ctgcaatccc
     8401 ataggaaatg ctatagcaca atcccataaa gatcgatgca aagaaggccg gtaaagcttc
     8461 ttccatatct agccatttga tgtctgcaaa agaagccatc atcattactc caactaaaat
     8521 caatgctggc gcagttgctt gatttggtac aatggcgatc agtggagaga ataaactact
     8581 taatgcgaat agcactgcca ctactactga agtcaaacca gtacgtccac cggccccgat
     8641 cccagctgca gattcgacat aagttgttgt attcgatgta ccaaagatag cccccacaga
     8701 agtagcgatc gcatcggcaa atagtgcttt atccattttt gttttgaacc cacgaccatc
     8761 ttccaacgcg atctcgtctt cttttgagaa aatacctgtg cggcgtcctg taccgataaa
     8821 tgttccgatc gtatcgaaag tatcagataa actgaatgcg atgatcgtca tcaatacttg
     8881 aggaatcttg gaagaatcac tgaataaaga ttgcatgcct tcagaaccaa atgctgcacc
     8941 gaaagttgtt cctaattctt taaatgaatt acctaacgaa ttcgtttgcc aatcaatgga
     9001 acttaaatca acaacaccca taaaaatacc aaggactgtg gtcgctacga taccgataag
     9061 aatagcccca cggacatttt ttacaactaa aatggctgtc agtaccaaac caatcacagc
     9121 caataagata ggagcgttgt caaagttggc taacgcaggg acgattccac catttatcgt
     9181 aacatttgtc gcttttccgc cttcaacgac agagctcgaa atagctgact ggtctgctga
     9241 aaaagataag aatcctgcat ttttgattcc gacatacgca acgaaaatac cgatcccgcc
     9301 accaatcgca tgttgaagac tttcgggaat cgcccgaata atcatttttc gaatatttgt
     9361 gacagtaata aaaatattga ttaatccgca aataaacacc attgccaagg cttgttgcca
     9421 agaataacca agcccaaaaa cgaccgtaaa agtgaaaaat gcgttcaatc ccataccagg
     9481 tgcctgagca tatggtacat ttgcgaacaa tcccattacc agcgtaccaa taatcgatgc
     9541 aatgattgtc gctagaaata ctgcttggaa gggcatacct gatgctgaca aaatcgtcgg
     9601 atttacgaat aagatataac tcatggcaaa gaatgtcgtt actcccgcca ttatttcagt
     9661 tgatacattt gtattgtttt tctttaaacc gaaaaacttt tccataaaaa gttccactcc
     9721 ctgaattttt ttctgatgga aaactataat aataaaaaat aagtaaaata gggcaaatcc
     9781 atcgaacaat ttcaaattat atagacgttt cattcgcttt tcaacgtttt tttaacaaaa
     9841 aaagcgaaaa taatacttaa cgttcgtgtt tagcttatgt ttagctattt atatagccat
     9901 aactgtagtt tttgttagga atagctgatt gctcttgtta attacctaaa atatgctaga
     9961 ctaaaacaaa tgctagttga ggaaggaagg acccttattg aataaaaaat taattgccat
    10021 cgatctggac ggaactaccc tcaatcaaga ttcgatgatt acatctaaaa caaaagagac
    10081 tctaaaaaaa gcaatcaatg ccggtcatca tgtcagtatt gctacaggac gcccattccg
    10141 aatgagccat cagttttacc aacaattaga attaacaaca ccgatggtta attttaacgg
    10201 cgcattagta cacatcccta atcagcactg ggatggtgaa agagaaacgt tgatcaatcg
    10261 tgaaatcgct tttgaaatct tatcgcaaaa aaagcagcta aatttagatt ttatcgctgc
    10321 tgaaaatcgt gatacttttt ttattgacag ttttgatttc tttgatgaaa aaatttttgc
    10381 ttcttctcgt ccaggagaga agaatttgct ttctcctaaa aatttgacga caaatcctac
    10441 atctttgctt gtccgaacag acaaacgttt tgcaggagct gtatctgctg aattaacacg
    10501 tcaatttggc agttatgtcg atgttcggac atggggtgga cctactgcca tcttagagat
    10561 tgtttcaaaa ggaatccaaa aagcaaaagg cgtgcaagag attgctaact acctgtctat
    10621 cgatcaaaaa gacgtcattg cctttggtga cgagcataat gatttggaat tgttggatta
    10681 tgcaggttgg ggagtagcta tggctaacgg tactgaccaa ctcaaaggca ttgcaaatga
    10741 tgtcactcct ttgagcaatc aggaagacgg tttagctgtt tatctggaaa aactacttaa
    10801 actataatag agaattagat tccacaaaaa agaggttgtg acaatttt
//
LOCUS       DAPBBV010000067        10616 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.069, whole genome shotgun sequence.
ACCESSION   DAPBBV010000067 DAPBBV010000000
VERSION     DAPBBV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.069"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            288..2234
                     /locus_tag="RD486_002532"
     CDS             288..2234
                     /locus_tag="RD486_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7664242.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2237..2692
                     /locus_tag="RD486_002533"
     CDS             2237..2692
                     /locus_tag="RD486_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7664243.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2706..4034
                     /locus_tag="RD486_002534"
     CDS             2706..4034
                     /locus_tag="RD486_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDT7664244.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            4068..4352
                     /locus_tag="RD486_002535"
     CDS             4068..4352
                     /locus_tag="RD486_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7664245.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            4354..4869
                     /locus_tag="RD486_002536"
     CDS             4354..4869
                     /locus_tag="RD486_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HDT7664246.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            4885..5547
                     /gene="rpe"
                     /locus_tag="RD486_002537"
     CDS             4885..5547
                     /gene="rpe"
                     /locus_tag="RD486_002537"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDT7664247.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            5554..6126
                     /locus_tag="RD486_002538"
     CDS             5554..6126
                     /locus_tag="RD486_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7664248.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(6313..7833)
                     /locus_tag="RD486_002539"
     CDS             complement(6313..7833)
                     /locus_tag="RD486_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDT7664249.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(8076..8261)
                     /locus_tag="RD486_002540"
     CDS             complement(8076..8261)
                     /locus_tag="RD486_002540"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDT7664250.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(8245..8427)
                     /locus_tag="RD486_002541"
     CDS             complement(8245..8427)
                     /locus_tag="RD486_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664251.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            8668..8886
                     /locus_tag="RD486_002542"
                     /pseudo
     CDS             8668..8886
                     /locus_tag="RD486_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9381..9980
                     /locus_tag="RD486_002543"
     CDS             9381..9980
                     /locus_tag="RD486_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7664252.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            10044..>10616
                     /locus_tag="RD486_002544"
     CDS             10044..>10616
                     /locus_tag="RD486_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HDT7664253.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT         3509 a         1670 c         1983 g         3454 t
ORIGIN      
        1 tataataaaa aaatacgaat tttagtgacg ccattatatt gtttttattt ttcaattgta
       61 atatttcata ttacttccat aataaggagt attttctatt ggaatatctt agctctttta
      121 aggatttctc cttttttgtt tctcattttt taagattatt tggatttcct ttacaacaaa
      181 cttccacaag tattattgac atagatgtaa ttgagggaag ggggttccag tgctagaata
      241 aataatgaaa agaggtaaca aatgctagcg ttaagaggtg aacaagtttg attgaaagac
      301 atgtaaattt attaaaatta ttaagtcgac aagaagactt taaacccgct tcttttttta
      361 gtgataaatt ggcagtgtcg accaagacca tttatcaaga tattgaattg ttggaagatt
      421 atgtagttaa ttaccaagta acaattgagc gattaccttc tttgggtatc aaactcatag
      481 gtgataggaa aaacgttgaa catttgattt catcggtaga aaattatctt gaaaaagata
      541 tttattctcc agaaaaaaga cgtgtcgaga tcattaaaga agttttgttt ggtgataagc
      601 ctgtttcttt aactcatttg tctcaaagtt ttatggttag taaaacatcg ttatacaatg
      661 acctgagaat tatcaataaa attattggca gtggagaagt taagttgcag tcatctgcag
      721 aaggaattag ttttactggt aatgaacaag caattcaacg agcaatcaag caacttgtat
      781 tctattatgc gaatgacatg gaatcaaaaa cattttttca agttttaaat atgttgtttg
      841 attcaaaagt tattagtgtc attcatgatt tgctattcaa tgattacagt gaactgactg
      901 aaaaggtttc tgattactat gttcggtcat tgatttctac tttagttatc caatgtaacc
      961 gtttactgaa aggtcatcat ttaactgttg aagaagaatt cctcttcaat agcattcgct
     1021 atatggaaac gtacattgtg gcaaatggtt taattgaaga attgaaggca aaattgaatc
     1081 ttccatttta tgacgcagat aaagaatatc tatgtcgtca actatttgca catcgtgtga
     1141 caaataattt aaaaaccagc aatgaagagt acgctatgag cgttcataaa ttgattgaaa
     1201 gaatgagtga gattgaaaaa attgatttga ctcaaaatga tcgattatat caatccttat
     1261 tgtatcatgt gccagcaatg gtccttcgtt taaaaaaagg tattaaaatt caaaatccgt
     1321 tattagaaaa tatcaaatct caatattcag aactctttag catagtatgg tacgccatgt
     1381 ccatccttga agaagaattt gatgtgactt taacggacga tgaagtttcc ttaattttga
     1441 ttcattttca gattgctatt gaagatcagt ccaaagcaaa taatatcatc attatttgcc
     1501 aatacggtat ttcttctgcg caattaattt acaataaagt tcgacggttt ttaccagcaa
     1561 aagataatgt agaaatatca actttagata agtttcattt agctgaaatt ggggaagttg
     1621 atttgattat ttcctctctt tcctttgatg caggtggtat acccttagta agggtatctc
     1681 cattggtaag taaaacagat tatatgaata ttatggaagc ttatactaaa tatttaatag
     1741 aagaaccttc gcgatttatt caaaatgaac tgattcctaa agcggttaaa gttcccacca
     1801 tatctaaatt tgttcaatca tctttagtaa aaacaggagt acaggtggaa agcaaagaag
     1861 aatgtttgga tttgatgatt tccgaactag aagccaattc attagttact gaagagtttc
     1921 gtgcttctat cttctctaga gagaaaatgg ggaatactaa tttagaaagt ggtgttgctt
     1981 taccgcatgc gaatccatca atggtcattg aatccaacat ttttattgta gcattaaaaa
     2041 atgcgattaa ttggggcgat cgaaaagtca aattagtcat tatggttagt ttagctgaag
     2101 aagatgtatc tgagattaga ggagtatatg aagaacttta ccaatttatt gggcaaaaag
     2161 aaatggtcga tcgcttgtta caagttcatg atagcgaaaa attactaaga atttttcaac
     2221 aaaaaggaga ataaaaatgt atctagataa agaattatgt ttatttcaat tagaagtgaa
     2281 agatcaaaaa gaattgtttc aagtaatgtc tgaacaatta aaaaacgctg gttgcgtgaa
     2341 agatagtttc ttagaaggta tcaccaaccg tgaacaagaa tttccaactg gattagaagt
     2401 aaatcaaatt gggtttgcta tcccacatac agattccgca catgtaaata gctctcaaat
     2461 ctgttttgcc tcattaaagg aaccactggt attttcagat atgacagata aatctcatga
     2521 aatacctgta cgtttagtct ttatgttggc aatgtcacaa cctcatgaac aaattgatac
     2581 actacaaaac ttagttagcc tatttcaaaa tgaagaaaaa gtaaatgaat tacttgcatg
     2641 taccacgaaa gaagcattta ttgagttagt acattctgca ggagtttatt aggaggaata
     2701 gagagatgga tattgtatta aatgcctttg aatggtttat tggattaggg tcaaacgtct
     2761 ttttaccact gattattttt gtaatcggga tattatttgg attaaaacct ggtaaagcat
     2821 ttgtttccgg cgttactgtt ggtatcggtt ctattggttt aggattagtt ttaagtttat
     2881 tatcagatgg tttaggaaca gcaattcaac aaatggggga acaatacggt ggtggcctga
     2941 atatcctaga tattggcgta ggtgttggtg gacctttggc ttactctaca tcattgggaa
     3001 ttttaatgat tccaatttca ttaattctta acttcatatt tgtggttttg ggttggacaa
     3061 aaacattgaa tgttgatatt tggaactttt ggttcgcaat tttcctaggt atgattactc
     3121 aatctgttac gggaaacttt tggtttggct taattggcgc gattgtcgca gtaattttac
     3181 aatggttctt agcagatcgt acacaaaaaa ctgttagcga atttttcggc tatccaggaa
     3241 tctctatcac acatatgatg ggattatcag gagtactatt tgccaaacca gtaaattggg
     3301 tttttgatcg tattcctgga tttaataaaa tagatgcaga tgcagaaaca ttaacaaaac
     3361 gtttcggtgt tttaggtgac acagttgtta ttggcctaat tatcggtatt gtagtgggta
     3421 ttatggcagg ctatgacgta gcaggaattg gaaacttagg aattatgact gcggcagtga
     3481 tgaagattat gcctaaaatg gtagcaatgt ttatggaagg tttaatgcca attgcagaag
     3541 cggcgaaaga atttacgaat aaaaagttaa atggtcgcca agtaaacatt ggaatggatg
     3601 cagcgttaac tgtgggtcat ccaactatta tgtcaacttc tctattgctt gtaccaatct
     3661 cattattgct agcactaatt cttccaggaa ataaagtatt accttttgga gatttagcat
     3721 tctttgcttt cgccatctgt ttaatgattc cttattttaa aggaaatatt gtgagatcat
     3781 tagtaggatg ttcgttgtat gttgttacaa cattatatat ggcaacatgg ttggcaccaa
     3841 ttatcactga tgtgtttaca ttagcaagtt tcgatgtggg gacagcagga ttagtaacta
     3901 tgttgttatg tggattatgg ccagtagggt tgtttgtttt attagcatct tactttggtg
     3961 taattggaat aggtggatta ggagttgttt tagtaggtgc ttctatctac atgaacaaag
     4021 tgaagaaagc ttaatcataa aattaaaata agaaagaaga gatcaatatg aaaaaattat
     4081 tagttatttg tggagcaggt catgctactt ctacaattgc agtagcaaaa ttatcaaaat
     4141 ggttggaaga agaaggatta acagatcaag tgaaaattta tcaatctaaa attgctgatg
     4201 agctaaataa aattgatgaa tatgatgctg tagtaagtac aacaattgtc cctgatgtaa
     4261 ttaaagctaa agtaacgaat ggcttgggct tattaacagg tattggtaca gatgccattt
     4321 atgcagatgt aaaagaaaga ttaggtgttt aatatgcgtt ttcatcatga cactttgact
     4381 attgaaacag tttcagggcg tccttcgtat catgatattc gaaaagaact tttagataca
     4441 gttgatacag caggtattga gaatggaatg ttagtaattt cgagcccgca tacaacttgc
     4501 tcactctttt ttgaagaaac gatgcatgac acaaactttt ttggtgatga ttatttacat
     4561 gtagacatca acaatgtaat ggaaacgatt attccaaaaa tgacgagtga aaatcaatac
     4621 aacagtccgg ggccaaaaca cattgatttt ggaacaagat tatctgatcc caattaccct
     4681 gcagaaaaat gggtcatgct aaataccgat gcacatttac gttcatctat ttatggaacc
     4741 aactcaatga ctttaattgt tcaagaaggt aaacttttat taggagaaat gggccgtgtc
     4801 tattttgtcg attgggatca actaagagag cgaactagaa caatcaatct catgattatg
     4861 ggagaataaa cgggggaata gagaatgaca attgctccat cattgttaaa tgcacctatc
     4921 gcagaagtta aagagttatt tgaaatctta aaagaaaaga atgttgatta tttgcatatt
     4981 gatgtaatgg atggctgttt tgtaccagat atggcttttg gaccaagtgt tattaaagat
     5041 attcgtccac taacagacgt tgtgtttgat gttcatttga tgattgatac accagaaaaa
     5101 attgtcacaa gatttgtaga agcaggagca gatattgtta ccttccacat tgaagctacc
     5161 aaacacgcaa tgaaggtcat tcagttagtc aaggaagcag gagcaaaagt agggattact
     5221 tttaatcctg caacaccagt cagttttatt gaaccagtat tatctttagt cgatcaagta
     5281 ttagtaatga caatcaatcc aggaacagag aataagcatt ttattcaaga gacagtagtt
     5341 aaaatcgaac agttagatgt aatacgcaaa caaaatgatt atacgtatga tattgaagta
     5401 gatggcaaga ttgataatca aacgattaaa gtttgttcta aagcaggggc ggatattttt
     5461 gtatcaggcg gtttcatctt caatgggaaa aataccccgc aagaacaaat tgataaacta
     5521 aatcaatcat tagaggaagt gaagtaaaag atcatgacca ataaagacca aaataaaaac
     5581 tatttagaag cgattatctt agaattacaa aataactcaa aacgtattaa ttctgtagag
     5641 ttagaacaat ttagtgagaa aattgttcaa gctaaacaca tctttctagc tggtgcagga
     5701 cgctctggaa ttgccatgca agcatttacg aatcgcttaa tgcatttagg tttttcagtc
     5761 agccttgtcg gtgaaattag ttcaccacat tcgcaacctg gagatttatt aattatctgt
     5821 tctggctcag gtgaaacagg tagtttaaaa aatttagcgg ccaaagcaaa tcaaagtggt
     5881 gtaagcattg ctttagttac catgaaaaaa gactcgtcga ttggtcaatt agcagattct
     5941 gttcttgtat taccaggtat taccaaagat gaaaatcaac gagaagaaga tactttttca
     6001 caacctatgg gttcaagttt tgaacaatta gcatttctca cctttgatag tttagtgtta
     6061 tctttaatgg ataaaacagg tgaaagctca gaaacgatgt ttgctcgaca tgcagatttt
     6121 gagtagtaga ttttaaagat aaaaaaccat tctctaaatg ctaattattc agcaaatatg
     6181 agaatggttt ttttatttga ttagacataa cttaataatt cagtagtttt gagcgtaagc
     6241 gtgtcataga atggtaccta aacacaaata gcccgatttg atacactcaa atcaggttat
     6301 ttgtggctta tattatttac agatttcttg tatctgctga ttccatggca aataagcgcg
     6361 tagcgcttca ggtgtcatcg aagacagatt gggaatctct gtaaaaagat gatttaaata
     6421 tttgcggatg tttaacccat tcgcaacagc tgtctggata atactcaata taattccatt
     6481 tgatctagcg ccttttaagc ttttagaaaa tagccagttt tttcgaccga tcactaactc
     6541 tttgatggca cgctctgctc ggttatttga aagttccaag cgtccatcaa gcaacacaat
     6601 ctgaagtccg tctttatgat tgactgcgta ttgaaccgcc tttccaagct gcgattttgg
     6661 caaataagca aaactctcac accaatgaaa aaattcagtc atcacaggct gcaacgtttc
     6721 cttcctcgct acaaaccttt cttctgcgct aagcttatta aaggtccgtt cgattcgaaa
     6781 catcttgtca cagaagtcta atcctatttt ggcatgactt tttggggacg gttgtttacc
     6841 caatgcttca aaaaactttc tgcgaacatg cgcccaacaa taaacattgt ttaccggcag
     6901 ctttccatag gccgcgtaac catcagtatg caagaaaccg ctaaatgatt ctaaaaaact
     6961 ttttggctca tcaacggaac gcgaatttgc gtgctcgtag agcacaactt gtttttcttc
     7021 gcttttacct gaagcatata accagtaaaa ggtcttttct ttatgagtat tcaatacccg
     7081 atagcttgtc tcatccgcgt gtaagacctc ctgattgctt aattcttgat gaaggcaatt
     7141 gtagattggc tctaaaacca tttcacttac cttgatatgc caattagtga tttttttacg
     7201 atcaagaggg aaaccaagtg catgccattc tttttcttgt cgatatgccg gcaccttttt
     7261 aacaaatttt tcccaaatac tctgtgtcac aattgaagag gaacctagac tattattgat
     7321 caacggttta ggaacaggcg cttttttgat ttttgtttct cctaatgctt cacattctct
     7381 gcaatgatag gcatgttggt agatgacttg tttttctata tgggcaggaa catacaatgg
     7441 ctcttctcta agccttgtcg caccgatatc atgtaaagta tgaccacagt cttcacacaa
     7501 acaatcggca ccttttaatt cataatgaat aggaacttca ggcagacctt ctaatgaaag
     7561 tgctttgagt cccttgcgtt ttctgcgttt aaaagaagat accgtaatgg gttcctggct
     7621 ttcttgtcca gtgtgctctg gttcattaaa agttgagtcg tctaataaat cgatttgccc
     7681 atctacgggt ggtgtttctt tttttcgtcc aaacaagcgt cgattcattt cagcaatttg
     7741 ttctctaaga agagtatttt cctgttgctg gatttcaagc aactgtgtta attgcttgat
     7801 ttgtacaaga agttcagatt ccatttttgt catttttaca ccaccattct agcgattttc
     7861 ttacatctat tataccattt tatgacaacg aaaaacagac aaaatccttg atttaacaag
     7921 gttttcgtct aatatatcgc accttttttc gtttctttta gcgtacattt ttcttcgatt
     7981 gaaaggccag tcagtaagac ttcttttctg gaacgcggcc attgaaggta cccactttca
     8041 aatcttttgt acattaatac aaatccattt tgatcctagt aaagagcctt gaagcgatct
     8101 ttcttcgtac cgcaaaataa gaaaagcgct tgatcgtaaa catcaaggtc atattcttct
     8161 ataacgaaag ctgctagtcc atcaattcct tttcgaagat ctgtttttcc acaaacgata
     8221 aaaatatgtt tcaatgcagt tgcatcaatg agcattggca ttcaactctt ttaacaaggt
     8281 atacaaaaga tatttatcca ttccattata aataaatatt tccttatctt ccgatttgat
     8341 tctgcaagct agttttggct tggtgtcaat ttgcgatttt tgagccgcac ttgaaaattg
     8401 aactggtaca atatcttttt tattcattcg tttttctcct tctatatttg atagtttaat
     8461 tatagaagaa agataatcgg cgtacgagat actatcctat gacacgctta catttaattt
     8521 aatattttgc ctcaaattag ccacactttt tatagaacta agaggaaaaa tgaagttttc
     8581 ttcctattaa tatagttgtt tgaaatctta aatatagcgt tttacgatgt aatgggaagt
     8641 atggtgaata aatcaactat gttcgtacga agcatttact caactaattt aatcgaatct
     8701 ttcaataaac aaatcaagaa atacagccac cgcaaggaac agttccaaaa tgaagagtcg
     8761 atggaacgtt tcttagtctc gtcttttgat acttacaacc aaaaattcct aggtcgcagt
     8821 cataaaggtt tccaacaggc cgaaggcgag ctcgaacaaa tgctgagtca accgatggag
     8881 aattagaaac aatctacagt agggaagaac cattgacaca aaattattga cgctcccaac
     8941 taaaagtgtc aaaataatga tgaaatcatt tagttcttat aaattagaaa agagaaaata
     9001 aatattccat atctacttta ttggatccgt aacatgacta aattctgaat actttttaaa
     9061 gcttatcatt tggtaaaact gaatataagt taattatata gactgaaaat tttgaatttt
     9121 cagaatagaa taacttaaaa gtactgacaa aattttttaa aggggcaata ttaatgttct
     9181 gagataatca aatcctaccg aaaatatcaa aaatccaatg tgacacaatc ggattgtgtc
     9241 tcattcgagg gaatcacaca atcccacgtg gctctaggca gaattgaatt tttgcttggg
     9301 gctttttcct tatattgatt ttgaatgaga cttattatat gttataatgc aattaagtat
     9361 cattggagag ggcgaagaaa atgaagacgg tagaacctat tcgagacaaa aaaaagatcg
     9421 atgcgatgaa ggcaatcttg gcttcgggaa aatatggcca acgaaatttg gttctttttt
     9481 cgattgggat caacaccgcc tatcgcattt ctgatttgcg tcaattgaag ctggccgacg
     9541 tgctggaaat ttcacgcggt cgcgtggtgg tcaaagatcg attagcgatg aaggaacaaa
     9601 aaacagctaa acataattcg gtctatattt ccaacaaatt gcgaaaaacg attttggagt
     9661 acgttcaaca ggaatttcct gatcaactcc ttcagcaaga ttttgacggt tatttgttcc
     9721 ctagtcgaaa agggacgaat gaaccgctca accgccaaag tctgtggcga atcattcatg
     9781 atgctggcac ggcaatcgga ttgaaagaca ttggcccaca ttccatgcga aaaacgttcg
     9841 gttactttct ctataaacag gggaccaaaa cagaaatcat tcagtccttg ttgaaccatt
     9901 cttctcagcg cgaaacattg cggtatattg gtattacaca agaagacaaa gatacagctg
     9961 taaaaagctt agatttataa tataaaagtt aagtttaaac atggatagtt ttaaattagt
    10021 agattgagtg ttgggaggaa agaatgagta cattatatat tataggaaac ggttttgatt
    10081 taagtcatgg tttaaaaact agatacactg atttttcaaa atgggttgaa aaaagtcata
    10141 gtgaaatatt cgataaaata gacacaatga taaatgaaaa taatgaggtg agaagtacag
    10201 ctgatgataa gataggttgg tttaattttg aaagtagttt gcatgagtta attcaaagtc
    10261 cagtctttga agattatgta gaagagtcta aggattatct cataggttat ggacatgaag
    10321 attggtcaga ttctgcccat catgattttc aaaatatggt ttatgattat gttgtttctc
    10381 tagaagaatt acaacaactt ttcaaggaat ggatacgcaa agaaatacag ccgacaatag
    10441 aacataaaat tccaaaatac caattttcgt ccgatgtact attctttaca ttcaattata
    10501 cagatgtttt ggaaattcta tacaagcaac cgaaagaaaa catatatcat attcatggca
    10561 gttatgacga tataataatc ggccactccg agaattttga caactttata ggagat
//
LOCUS       DAPBBV010000068        10534 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.070, whole genome shotgun sequence.
ACCESSION   DAPBBV010000068 DAPBBV010000000
VERSION     DAPBBV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.070"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(1..657)
                     /locus_tag="RD486_002545"
                     /pseudo
     CDS             complement(1..657)
                     /locus_tag="RD486_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            complement(662..1429)
                     /locus_tag="RD486_002546"
     CDS             complement(662..1429)
                     /locus_tag="RD486_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7664254.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1917..2342
                     /gene="lacA"
                     /locus_tag="RD486_002547"
     CDS             1917..2342
                     /gene="lacA"
                     /locus_tag="RD486_002547"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HDT7664255.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2359..2874
                     /gene="lacB"
                     /locus_tag="RD486_002548"
     CDS             2359..2874
                     /gene="lacB"
                     /locus_tag="RD486_002548"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HDT7664256.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2885..3817
                     /gene="lacC"
                     /locus_tag="RD486_002549"
     CDS             2885..3817
                     /gene="lacC"
                     /locus_tag="RD486_002549"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HDT7664257.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTVSHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3820..4800
                     /gene="lacD"
                     /locus_tag="RD486_002550"
     CDS             3820..4800
                     /gene="lacD"
                     /locus_tag="RD486_002550"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDT7664258.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4828..5145
                     /locus_tag="RD486_002551"
     CDS             4828..5145
                     /locus_tag="RD486_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7664259.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5145..6851
                     /locus_tag="RD486_002552"
     CDS             5145..6851
                     /locus_tag="RD486_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7664260.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTVLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            6993..8399
                     /gene="lacG"
                     /locus_tag="RD486_002553"
     CDS             6993..8399
                     /gene="lacG"
                     /locus_tag="RD486_002553"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HDT7664261.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8422..8694
                     /locus_tag="RD486_002554"
     CDS             8422..8694
                     /locus_tag="RD486_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HDT7664262.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            8715..9614
                     /locus_tag="RD486_002555"
     CDS             8715..9614
                     /locus_tag="RD486_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDT7664263.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
     gene            complement(10086..>10534)
                     /locus_tag="RD486_002556"
     CDS             complement(10086..>10534)
                     /locus_tag="RD486_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7664264.1"
                     /translation="FNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFHTDRGKEF
                     DNQAIDELLTTFDINQSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLELF
                     DYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
BASE COUNT         3303 a         1798 c         2108 g         3325 t
ORIGIN      
        1 gtttatgacg acttttggaa gtaaaaatcc atccattatc tttataatca ggattgaatc
       61 ttatatgttg gtgatttaac tcaatttcct ctttaagaat ttctatagcc cttttagata
      121 attggacatt ttggtaactt tgtaagtttt ttacattacc ttcatagcta ttttctgcag
      181 ctcctccgtg agtggactga ctaatgatga tattttgctt ttcaaaatat tgataggcac
      241 caatattttg gagttttcga ctctgtaagt caacagggcc attagttaga atacctattg
      301 ggatgcggtt tttatgtaga gccagtagta gttgatgtat ctcaggaatc atcgtaatct
      361 gatcgagttc atattcatag tcagcttgga agtctagagc ttctgtccta gaaatactat
      421 cgatgccaaa ttcttccata gtcttctgac agcgaaaaat tctaagctgc tcaatactga
      481 tgagtttttc gtgtatttag gaaaagcaac atcagaccaa catctgaaac gtttgtaaat
      541 gttatctatt tgttggatat caatcgttgg aaaacatttc tcaacgctac ttttaaaggg
      601 gagttgatgg tcataaagag tgtcatcaag gtcaaaaaca atatttttat aagtcataat
      661 tctagtccgc ttttaaaata gtagtgtact ggctaaattc ctctaagtgt tgagggctaa
      721 tctggttatc tgtaatgatg gtatcgagtt gatctagatt atagaagtta aagaaatcgt
      781 atcgatcgaa tttagtactg tctactaata agaatttttc tacagcattg tttagggcaa
      841 gttgttgaat cacaccttcc ttgtcactat atgtagcaat agaattatgg gtaacagcat
      901 ttgcactaac aaaagctttg gcaaatctaa ttgcttttaa atttgtcgaa gccattgaac
      961 ctacaaaagc tccagttatt tctctatatt caccgccaag aagcaataaa tcaatggttt
     1021 cgctatcatt tagaatcaag aacacaggga gactatttgt aatgacacga attttataac
     1081 ctttacgacc tttcaattct aatgccagtt gttcaagtgt agttccgggt ccaataaaaa
     1141 tagtatcgcc atctttgatt aaagagcagg cttttttagc aatgtcaatt ttttcttttg
     1201 tatttagact tttcttctcg atatgtgtct tttcaagtgg ctttttagag gaaagtaatt
     1261 gtgcaccacc atgagtacgt gttaaaagtc catcagcttc tagagcatca aggtctctac
     1321 gggctgtcat atcggaaata tctagttcat ctattatttc ttttatggtt atggtcccat
     1381 caatctttaa catatctaaa attttttcta atcgtcgttt tttgttcata tgaagaccct
     1441 tctttcataa agtaattttt ttccaaagat aattctcttt taattgtatc ataaaagaca
     1501 atattttcaa ggtaaaacaa acaatttcaa acaaaaacaa atgttagatg atgaaataag
     1561 aacagtggat tgacgtatat tagcttaggt cagattttgt ataagacgaa aataaagtag
     1621 gacctcttaa tcagtaagtt atagaaagta aaagactttt gtaatacttg aatagatatt
     1681 tcacgtccat tttgtgatgg attaaatgaa caaaaatgaa caataattta acggtgttat
     1741 ctatttttta aaaaaacaaa taaaaaaaca aaaaataaac aaaaaagtgt tgctttttgt
     1801 ttgaatgctt gatattatat aaacaaagaa atgatgaaaa cgttttttcg aacattttgc
     1861 aaaatgtttt ctacttctac gtagcatttc tttctaaaat ttaggaggtg gtcaaaatgg
     1921 ctattgttgt tggtgcagat ctcaaaggta cgagattaaa agatgttgtg aaaaattttc
     1981 ttgtagaaga aggttttgag gtaattgatg tgactaagga cggacaagat tttgttgatg
     2041 ttaccttggc agttgcctct gaagtaaata aagatgagca aaacttaggt attgtaattg
     2101 atgcttatgg agctggtcca ttcatggtag caactaaaat taaaggtatg gttgcagcag
     2161 aagtttcaga tgaacgctca gcttatatga cacgtggaca taacaattca cgaatgatta
     2221 cggttggcgc tgaaatcgtc ggtgatgagc ttgctaaaaa catcgctaaa ggtttcgtca
     2281 atggtaaata tgatggcgga cgtcatcaaa tccgagtaga tatgcttaac aaaatgtgtt
     2341 aaggaaagga gttaaggaat gagaatcgca attggatgtg accacattgt cacagatgaa
     2401 aaaatggcag tatcagaatt cttgaaatca aaaggacatg aggtccttga tttcgggaca
     2461 tatgaccacg cacgtactca ctaccctatc tatggtaaaa aagtcggtga agcagtagta
     2521 agtggtcaag cagacttggg agtatgtatc tgtggtacag gtgtcggcat taacaatgca
     2581 gtcaataaag ttccaggtgt tcgctcagcg ttggttcgtg atatgacatc agctatatat
     2641 gcaaaagaag agttaaatgc gaatgttatc ggtttcggtg gaaagattac tggtggtctt
     2701 cttatgaatg acatcattga agctttcatt gaagctgagt acaaaccaac agaagaaaat
     2761 aaaaaattga ttgcaaaaat cgaacacgtt gaaacacata atgcacatca agcagatgaa
     2821 gatttcttta cagaattcct tgaaagatgg gaccgtggtg actaccacga ttaaggtata
     2881 acaaatgatt ctgacagtca cactaaatcc ttcagtagac atctcttatc ctctagaaac
     2941 attgaaaatt gatacagtga atagggtgaa agatgttagt aagacagctg gtggaaaagg
     3001 cttaaatgtt actagagtct tgtatgaatc tggtgataaa gttactgcta caggtttctt
     3061 aggtggtaaa attggtgaat ttattgaaag cgaattagaa caatctcctg ttagtccagc
     3121 tttttataaa atctcaggaa acactagaaa ctgtattgct atcttacacg agggtaacca
     3181 aacagaaatt ttggaacaag gaccaacagt ttctcatgaa gaagcagaag gttttcttga
     3241 ccactatagc aatcttatta aacaatcaga agttgtgaca atttcaggaa gtttaccttc
     3301 aggacttccc aacgattatt atgaaaaact tatccaactt gcttcggatg aaggagtagc
     3361 agtcgttttg gattgttcag gtgcacctct tgaaacagtt ctaaaatcgt cggctaaacc
     3421 tactgccatc aaacctaata atgaggaact ttcacagttg cttggaaaag aagtaacaaa
     3481 agatattgaa gaactcaaag acgttcttaa agagtcactt tttagtggta tcgaatggat
     3541 agtggtctca ttaggtcgaa acggtgcctt tgcaaaacat ggtgatgttt tctataaggt
     3601 agatattcct gatatcccag ttgttaatcc agtcggatca ggggactcaa cggtagctgg
     3661 tattgcatca gctttaaata gtaaaaaaag tgacgctgac ttattaaaac atgcgatgac
     3721 attgggtatg ttaaatgctc aagaaacaat gacagggcat gtgaatatga ctaattacga
     3781 aacactaaac tcacaaattg gagtaaaaga ggtataaaaa tggtacttac agaacagaaa
     3841 cgcaaatctt tggaaaaaat ttcagataaa aacggtgtta tctcagcttt ggcatttgac
     3901 caacgtggtg ctttgaaacg tttgatggca cagtatcaag atacagaacc aactgtagct
     3961 caaatggaag aactaaaggt tttggttgct gatgaactta caaaatacgc ttcttcaatg
     4021 ttgcttgacc ctgaatatgg acttccagca acaaaagcat tggataaaga agcaggtctt
     4081 cttcttgcct atgaaaaaac aggttatgat acatcaagta caaaacgttt gcctgactgc
     4141 ttggatgttt ggtctgcaaa acgtatcaaa gagcaaggcg ctgatgccgt taagttcttg
     4201 ctttactatg atgtagacag ctcagatgaa cttaaccaac aaaaacaagc ttatattgaa
     4261 cgtgttggtt ctgaatgtgt cgctgaagat attcctttct tcttggaaat ccttgcttat
     4321 gatgaagaaa tctcagatgc aggttctgtt gaatatgcaa aagtgaaacc tcgcaaagtc
     4381 attgaagcga tgaaagtttt ctctgatcca cgctttaaca ttgatgttct taaagtagaa
     4441 gtaccagtta acgttaaata tgtcgaaggt tttgctgatg gtgaagtggt ttacagtaaa
     4501 gctgaagctg ctgacttctt taaagcacaa gaagaagcga ctaaccttcc atacatctac
     4561 ctaagtgcag gtgtatctgc taaattgttc caagaaacat tgcaatttgc tcacgactca
     4621 ggtgccaagt ttaatggtgt gctttgtgga cgtgctactt gggcaggatc tgtagaacct
     4681 tacatcaaag aaggtgaaaa agcagcacgt gaatggttgc gtactactgg attcgaaaat
     4741 attgatgaac ttaacaaagt tcttgttaaa acagctagtc catggactga taaagtatag
     4801 taaaaacata aaacggagga tattgttatg aacagagaag agatgactct cttagggttt
     4861 gaaattgttg cttatgctgg agatgctcgc tctaaacttt tagaagcgct taaagcggct
     4921 gaaaatggtg atttcgctaa ggcagatagt cttgtagtag aagcaggaag ctgtattgca
     4981 gaggctcaca attctcagac agctatgttg gctcgagaag cttctgggga ggaacttcca
     5041 tacagcgtta ccatgatgca tggtcaggac cacttaatga ctactgtctt attaaaagat
     5101 gtgattcatc acctcatcga actttataaa agaggagcaa aataatgcat aaactcattg
     5161 aacttattga gaaagggaaa ccgttctttg agaaaatctc tcgaaacatc tatcttcgtg
     5221 ctattcgtga tggatttatc gctggtatgc cagtcatcct tttctcatct atctttatcc
     5281 ttattgccta tgtcccaaat gcttggggat tccactggtc aaaagacatt gagaccttct
     5341 tgatgactcc ttatagctat tcgatgggta tcctagcatt ctttgttggt ggtactaccg
     5401 ctaaagcttt gacggactca atgaaccgtg acctacctgc gaccaatcag attaacttct
     5461 tatctacgat gctagcgtct atggtagggt tccttttgat ggcagctgag cctgcaaaag
     5521 aaggaggctt cttgacagcc ttcacgggaa caaaaggtct tttgacagca tttattgcag
     5581 cctttgtgac agttaatgtt tacaaggtct gtgtgaaaaa taatgttact attcgtatgc
     5641 ctgaagaggt tccaccaaat atctctcaag tatttaaaga cttgattcca ttcactgtag
     5701 cggttgttct cctttatgga tttgaactca ttgttaaggg aactcttggt gtaaccgttg
     5761 cagaatcaat cggtaccgtt cttgctcctc tcttctcagc tgcagatggt taccttggaa
     5821 ttacacttat ctttggtgct tatgccttct tctggtttgt tggtatccac ggtccttcaa
     5881 ttgtcgaacc agcaatcgct gctatcactt atgccaatat cgatgccaac ttgcatctta
     5941 tccaagctgg acaacatgca gataaagtta tcacttctgg tactcaaatg tttattgtta
     6001 ccatgggtgg aacaggagct acattgattg ttccattctt gttcatgtgg atttgtaaat
     6061 cagaacgtaa ccgtgccatc ggacgtgcct cagttgttcc aacattcttt ggggttaatg
     6121 agccaatctt atttggtgca ccaatcgtat tgaatccgat tttctttgta ccgttcattt
     6181 tcgctccgat tgtcaacgtt tggatcttta aattctttgt tgacacattg aacatgaact
     6241 cattctctgc caaccttcca tgggttactc ctggtccgtt gggaattgta ctcggtacta
     6301 acttccaagt tctatcattt atcttagccg gactcttggt agttgttgat actatcattt
     6361 attacccatt tgttaaggta tacgatgaac aaattcttga agaagaacgt tctggtaaaa
     6421 caaacgatgc tcttaaagaa aaagtagctg caaacttcaa tactgctaaa gcagatgccg
     6481 ttcttggaaa agcaggcgtt gctaaagaag atgtagcagc aaacaataat atcacaaaag
     6541 aaactaatgt ccttgttctt tgtgcaggtg gaggtacaag tggcttgctt gccaatgcct
     6601 tgaacaaagc agcagcagaa tacaatgttc cagtcaaagc ggcagcgggt agttacggtg
     6661 ctcaccgtga aatgttgcca gagtttgact tggttatctt ggctccacag gtcgcttcaa
     6721 acttcgatga tatgaaggct gaaacggata aattgggcat taaacttgca aaaactgaag
     6781 gagctcaata tatcaaattg acacgtgatg gacaaggtgc tcttgcattt gttcaacaac
     6841 agtttgatta ataaatttgt aaaagttatt tgagacgaga ttattctttc agttccttat
     6901 aatattgtta accatatcat tgcatttcat ttccttggtt tccggaactc agaatatcgt
     6961 ctcaaatgct ttttttgaaa ggatttatag ttatgactaa aacacttcct aaagatttta
     7021 tttttggtgg tgctacagct gcttatcaag cagaaggtgc gactcacacg gatggtaaag
     7081 gcccagttgc atgggataag tatcttgaag acaattattg gtacacagca gagcctgcaa
     7141 gtgattttta ccataaatat cctgttgatt tagaattagc tgaaaaatat ggcgttaatg
     7201 gtattcgtat ttcaattgcc tggtctcgta ttttcccaac tggctatggc gaagtaaatg
     7261 aaaaaggtgt tgaattctac cataatcttt ttgccgagtg ccacaaacgt catgttgagc
     7321 cattcgtgac tttgcaccac tttgacacac cagaagttct tcactcagat ggagatttct
     7381 taaaccgcga aaatatagaa cactttgtag attatgccgc tttctgtttt gaagagttcc
     7441 cagaagtaaa ctactggaca actttcaatg aaattggccc aattggagat ggtcaatact
     7501 tggttggtaa attccctcca ggcattcaat atgatcttgc caaagtcttc caatcacacc
     7561 acaatatgat ggtttctcat gcacgtgctg tgaaattgta taaagataaa ggttataaag
     7621 gcgaaattgg tgtagtacat gcgttgccaa ccaaataccc ttatgatcca gaaaatccag
     7681 cagatgttcg tgccgctgag ttagaagata tcatccataa caaatttatc ttggatgcaa
     7741 cctaccttgg acactattca gataaaacga tggaaggggt caaccacatc ctagctgaaa
     7801 atggtggaga acttgatctt cgtgatgaag acttccaagc acttgaagca gctaaagatt
     7861 tgaacgattt ccttggtatc aactactaca tgagtgattg gatgcaagcc tttgatggtg
     7921 agactgaaat cattcacaat ggtaagggtg aaaaaggaag ttctaagtac cagattaaag
     7981 gtgttggtcg ccgaatcgca ccagattatg tgcctagaac ggattgggac tggattattt
     8041 atcctgaagg cttgtatgac caaatcatgc gagtgaaaaa tgattatcca aactacaaga
     8101 agatttacat cactgaaaac ggtcttggat acaaagatga gtttgtagat aataccgttt
     8161 atgatgatgg tcgtattgat tacgtgaaga aacacttgga agttttatca gacgcaattg
     8221 cggatggtgc aaatgttaaa ggttacttca tctggtcact tatggatgtc ttctcatggt
     8281 caaacggata cgaaaaacgt tatggactat tctatgtaga ctttgacacg caagaacgct
     8341 atcctaagaa atcagctcat tggtataaga aagtagcaga aactcaagtg atagagtaat
     8401 attacttgaa aatgtaaaaa attgttatcc gatactttag aaaaagtaca acacttattt
     8461 agaccaggct ttgaaaaggt atatattgtt agtttcgaag attgtcctat gattcctgag
     8521 cttgaagcta ccccgttgct aaaatgtggt aaatggtatg tttcaactgg aaaagagtgg
     8581 atttgccatt ctgatttaga gttatcagca tttgaatggg aatttttaca atcactcgat
     8641 gtagaaatac gtgagactat tcacttcgag gtaaattatt tgcctttcca ataataaaaa
     8701 gaaaggaatt agttgtgact atcgaattaa aaaacgagta tcttactgtt cagtttaaaa
     8761 cacttggtgg tcaactgact tcgattaaag acaaggatgg gatagagtat ctctggcaag
     8821 ctgatccaaa ttattggaat ggacaggcgc ctattctatt tcctatctgt ggtagtttac
     8881 gaaatgattg ggctatttat agacctcaag aaagaccttt ttttacaggt cttattcgta
     8941 gacatggttt tgttcgaaaa gaagaattta ttctggaaga agtcaatgat aatagcgtga
     9001 cctttagtat taaaccaaat gctgagatgc ttgataatta cctatatcag tttgaactga
     9061 gagttgttta taccttgaat ggtaaatcaa ttagaaccga atttcaggta acgaacttgg
     9121 aaatggaaaa aacaatgcct tactttattg gagcccatcc agcattcaat agtcctttag
     9181 tagaaggtga aaactatgag gattattata ttgaatttag tgaggttgag tcttgctcga
     9241 taccaaagag ttttcctgag acaggattat tagatttgca agatcggaca ccttttttgg
     9301 aaaatcaaaa aattctcgat ttggactact cacttttttc ccatgatgcc attacacttg
     9361 accagctcaa gtctcgtagc gtaacgcttc ggtcaaggaa gtctggtaaa ggtcttcgag
     9421 tagattttga tgattttccg aacttgattc tgtggtctac aactaataaa agtccattca
     9481 ttgctttgga accttggagt ggtctctcca cttcacttga agaaggtaat ttcttagaag
     9541 ataaaagaca ggtaacgaaa atttcacctc aagaaacttc tagaaaaatc tatgatatta
     9601 ctatccttaa ttaaaatttg ttattatttg agtcttcaat aagatttgaa tactcttacc
     9661 ttgtgatgat agattggtct tctccgtgcc agtcttacat cgcaaggttt ttaagttttt
     9721 tgtgggtcta tgtcaactgt agtgggtgac gaaaagctaa tatctaaaga cagtctggta
     9781 gtaaaaaata agattattta ctacttcttg atttaaaata atagtggagc cattaatttg
     9841 tggcaaattt aatttaatat tttgcctcaa attagccaca ctttttatag aactaagagg
     9901 aaaaatgaaa ttttcttcct attaatatag ttgtttgaaa tcttaaatat agcgttttgg
     9961 aatggcaaca gtttttttga caaattttat aaggtgcaga acttctttcc gtatgctatt
    10021 ccgattgtcc ttgacaatga gcctcctcgg atgtgacgat cttcggcagg agctaacagt
    10081 taaagttaga ctgcctcgct agcgttagca catccgagct cattatcaag gattcgctgc
    10141 gccaatctct ggttacggta accaaccggt gtctcgtagc caagtgtacc gtgcaaccga
    10201 aggtggttcc accaattgac atagtcaaat aactccaaat ccaattgttg taaggtttca
    10261 aatgtgtatt gatagacaaa ttctactttc agcgacttat aagttgattc agctacggca
    10321 ttatcaaaag gacagccttt atgactcaat gattgattga tgtcaaaagt tgttaataat
    10381 tcatcaatag cttggttatc aaactctttt ccacgatcag tatgaaaaat ctcaacctct
    10441 gtcagaggtt gtttgatacg gctaaatgct ttttttacta gaacggcatc tttatgttct
    10501 ccacaagaat agccgagaat ttctcgattg aaca
//
LOCUS       DAPBBV010000069        10178 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.071, whole genome shotgun sequence.
ACCESSION   DAPBBV010000069 DAPBBV010000000
VERSION     DAPBBV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.071"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..264
                     /locus_tag="RD486_002557"
     CDS             <1..264
                     /locus_tag="RD486_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDT7664265.1"
                     /translation="KMNSGNLISSWMIQQDSLFTKKMLRGYYLERKIIDEYEVAEKIT
                     TFSANSYRRNINLLESYTMNKPSDNFSFRFAFRAKSKKTSPIK"
     gene            424..2310
                     /locus_tag="RD486_002558"
     CDS             424..2310
                     /locus_tag="RD486_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7664266.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            2322..3269
                     /locus_tag="RD486_002559"
     CDS             2322..3269
                     /locus_tag="RD486_002559"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDT7664267.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            3289..3816
                     /locus_tag="RD486_002560"
     CDS             3289..3816
                     /locus_tag="RD486_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7664268.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(3879..4532)
                     /locus_tag="RD486_002561"
     CDS             complement(3879..4532)
                     /locus_tag="RD486_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDT7664269.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            4664..5506
                     /locus_tag="RD486_002562"
     CDS             4664..5506
                     /locus_tag="RD486_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7664270.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            5664..6560
                     /locus_tag="RD486_002563"
     CDS             5664..6560
                     /locus_tag="RD486_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7664271.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            6563..7276
                     /locus_tag="RD486_002564"
     CDS             6563..7276
                     /locus_tag="RD486_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HDT7664272.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            7296..7814
                     /gene="msrA"
                     /locus_tag="RD486_002565"
     CDS             7296..7814
                     /gene="msrA"
                     /locus_tag="RD486_002565"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7664273.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            7811..8038
                     /locus_tag="RD486_002566"
     CDS             7811..8038
                     /locus_tag="RD486_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HDT7664274.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            8190..8741
                     /gene="lepB"
                     /locus_tag="RD486_002567"
     CDS             8190..8741
                     /gene="lepB"
                     /locus_tag="RD486_002567"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7664275.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(8824..9324)
                     /locus_tag="RD486_002568"
     CDS             complement(8824..9324)
                     /locus_tag="RD486_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDT7664276.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(9603..10001)
                     /locus_tag="RD486_002569"
     CDS             complement(9603..10001)
                     /locus_tag="RD486_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7664277.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         3666 a         1765 c         1986 g         2761 t
ORIGIN      
        1 aaaatgaact cggggaattt gatttcttcg tggatgatcc agcaagatag tctgtttacg
       61 aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca ttgatgaata cgaagttgct
      121 gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga atatcaattt gttagaatct
      181 tatacgatga acaaaccatc tgataacttt tctttccgat ttgcgtttcg agcaaagtca
      241 aaaaaaacga gtccaataaa ataaaaaggt aaaaattttc aagttttata aaaaacaaaa
      301 catatcagaa caggatcgaa tcggtcctgt tctttttttg agaacacaaa aagaacaaat
      361 accaaaaaaa ttttcctgaa gttcactatt tttatgatac aatatccaag ataaggaggg
      421 aacatgttga aagaattaaa agtaactgac ctcaaaaaaa cttatggtga aaaagatttg
      481 tttgaccaga tttctttttt ggtccacgaa aaagaccgta tcgggttgat tgggacgaac
      541 gggacgggta aaacaagtct cttaaatatt attgccggta tcgatagcag cgacggtgat
      601 cggcaaacag tgttttatcc aactgattac cgtattggtt atctttctca agcagctgaa
      661 ttttccgatg aattaactgt tctccaagca gtctttcaag gaaacagccc cttgatccaa
      721 actgttcgag catatgagga agcattgatc gaactagggg aaaacggaga agaccctgat
      781 gtgcaaaaac gttatgctaa agcagaagaa caaatgaata aagaagatgc ttggactaca
      841 gataccaacg caaagattat tttgcaaaaa ttaggaatca gtgaattaga taaaaaaatc
      901 agtactttat caggtggtca gaaaaaacga gttagtctgg cgcaagtgtt gattgatgaa
      961 cccgatttac tattactaga cgaaccaaca aaccatttag attatgaagc gatcgagtgg
     1021 ttggaaaact atttgaaaca ataccgtggc gcactattga tggttaccca cgatcgttat
     1081 tttctagata gagtagcaaa ccgaatcttc gaactttcat ttggaaaatt atacgagtat
     1141 aaaggaaatt atgaagctta cgtcttagaa aaagcagaac gtgatcgtgt agaagtagaa
     1201 caagaagaaa agcgcaagcg gctttataaa caggaattag cttggatgag ggctggcgta
     1261 caggcacgtg gcaccaagca gcaagcacgg atcaaccgtt tcgaagatct aaaggagaac
     1321 ttgtaccaag taaaccaaga agatgattta gagctgaacc tagcgacaca acgtttaggg
     1381 aaaaaagtac tggaaatcaa agatggcagt taccgtataa atgaccaaac actgctagaa
     1441 catttagatt tattgattca atctcgggaa agactaggta ttactggtaa aaatggtgcg
     1501 ggaaaatcga cattgcttaa tattctagct ggcagaattc ccctggatag cggtacaatg
     1561 tctatcggtg aaacggttca tcttgcgtat tatacacaag aaaatgaaga aatggcacca
     1621 gataaacgga tgattgctta cttacaagaa gctgctgaag aagcaaaaac agcagatggc
     1681 agtcaaatcg gagtagcaga attacttgaa cgatttttat ttccaagatt tatgcatggg
     1741 acactgatag gcaaactttc aggcggagaa aaacgccggt tatttttgtt gaaactgctg
     1801 attcagcaac ctaatgtttt attattggat gaaccgacca atgatttgga catagcaaca
     1861 ttgacgattt tggaagatta ttttagaagt tttccaggtg ctgtgatcac tgtttcccat
     1921 gaccgttatt tcttggacaa ggtagcagat aagttattag tattccaagg aaacggaaaa
     1981 caagaacttt attacggaaa catgtccagt tatttactga agcaaaaaga gacccagcag
     2041 cctgctgaaa aagcgaaacc aaaaatacag agcaaggaac ctgctgaaaa gaagaaatta
     2101 tcttacatgg aacaaaaaga atgggaaacg attgaagatg agattgcaga acttgaagaa
     2161 aaaatctcat tgctccaaga agagatgaat catcaaggag ataatttcac tcgattacaa
     2221 gaattgcaaa acgacgtatc tgaaacagaa gcacaacttg aagaaaaaat ggcacggtgg
     2281 gaatacttga gtgaatgggt agaagattag gaggaaaaag gatggaacaa gcgtatcttg
     2341 acttaggaag aaaattgttg gaagaagggc atcgtaaaga agacagaaca ggcacaggca
     2401 cattaagctt attcggatac caaatgcggt ttgatctgca aaaagggttt cctttgttaa
     2461 caacgaaacg agtacctttt ggattgatca aaagcgaatt gctttggttt ttaaaaggag
     2521 atacgaatat ccgctatcta ttacaaaata aaaaccatat ttgggatgaa tgggcatttg
     2581 aacgctacat caaaagtcca gactataatg gaccagatat gactgatttt ggccatagat
     2641 gtttgacaga tcctgaattc aatgaagaat ataaaaagca gagcaagctt ttttgcgaga
     2701 agatcctaac cgatgattcc tttgctgaaa catacggcga tcttggacac atctacggct
     2761 atcaatggcg tcactgggaa acaaaagacg gtggctttat cgatcaaatc aaacaagtga
     2821 tcgaagcaat caaaaagact cctgattcta gaagattgat cgtttctgca tggaatccgg
     2881 aagatgttcc tagcatggct ttgcctcctt gtcatacgat gtttcaattt tatgttcaag
     2941 agggacggct aagctgccaa ttgtatcaac gcagtgggga tgtgtttcta ggcgttccgt
     3001 tcaacattgc aagttatgcg ttgctgactc acctaattgc acatgaaaca ggtttagcgg
     3061 ttggcgaatt tgttcacaca ttaggagatg ctcatcttta tatcaatcat atcgaacaaa
     3121 tgaaagaaca attgagccga gaaatacgcg catttccgac tttagttttg aatcaggaaa
     3181 agcagtcagt atttgatttt gagatggaag atatccaatt agaaggatat gacccacatc
     3241 cggcgatcaa agctcctatc gctgtttaga atcagaaagg atgagaaaat gttagctgca
     3301 atttgggcac aggatgaaaa cggattgatt ggaaaagaag accgtcttcc ttggcgtttg
     3361 ccaaatgatc tgaaattctt caaacaaatg acagaagcaa atacactagt gatgggacga
     3421 aaaacattcg aagggatggg tagccgtccg ttgccgaatc gtcagacgat tgttttgacg
     3481 agagattctt cctataaagc agaaggcgtg catgtcatgc atagtgtgga agacgtgctt
     3541 gctctggaaa aagaaacaga cggtatcttt ttcatcgctg gagggtcagc tgtttatcaa
     3601 gaatttctgc cattttgtac gatattatac cgtacagtca tccatcatgt attcgatgga
     3661 gatgcttatt ttccacctgt tgactggtct gattggtcac tgatcaatac tagtcaagga
     3721 gaaatggatg aaaaaaatcg ttatccgcat caatttgaaa cgtatcagcg taatgagaat
     3781 cctgtaaaaa gcgggacagg cgaattgacg atataaaaaa gctatggata gactagctgt
     3841 tatttagagc tgtcccatcc atagctttat tttttttatt aagtaaagaa taaaacagag
     3901 aagtacataa aacctgcacc taacataaca aacaaatgcc aaacaacatg catatagcgg
     3961 atagaattca agctataaaa gaatgcgcct atcgtgtaag aaagcccgcc tgctaccatc
     4021 aaaataacac cagtcattcc aagagagtga taaagaggaa cagcagccac gacacagagc
     4081 caccccataa aaatatagat gatcgtagat acttttgata ctctctcccg tttatgcaac
     4141 gtcaacgctt tatatataat gccaagaatc gcaaacaacc agattaatac aaataaagtc
     4201 caacctagcc atcctcggat actcagcaaa caaaaaggag tataacttcc tgcaatcaaa
     4261 agaaaaatcg aactatgatc gaatacttgg aacacctttt ttgcttttgt aaaaatcaat
     4321 gaatgaaaca aagtagacgt taaaaataaa agaatcatca tcgatccata gatagcataa
     4381 gagacaatat ggagggagga atgcaagtgg gcacctttta ctaaaagaac cactagtccc
     4441 gcgatactca atccagtccc aattccatgg gtgactgcat taaacacttc atttaatatt
     4501 tcatacgttc gattaaattt cgttttttcc atgaaaacgg ctcctttact aggtgtaatt
     4561 aatgaaaaat cattatttgt ctgttatact aaaaatagaa attgtcttac atgtagttta
     4621 acatgaataa ggcatcttgt taaagaaaga gagagagaaa ataatgacaa atgtaaaaat
     4681 cgtaacagat tcttcatgta cgatggaaaa aaatgtacgc gatgctttag gcattcgtgt
     4741 catgccgcta tccatcatga tcgacggaac agtatatccc gatgatgacc aactagacgg
     4801 cgaaagattt atggaaatga tggcgaaagc aaaaaatctg cccaaaacaa gccaaccacc
     4861 aattggagaa ttcatctcga tgtatgatga gctaggagaa gacggcagtg aagtgatttc
     4921 gatccatatg acaaaaggct tgagtggaac agtagaagca gcaagacaag ccagtaatct
     4981 aacaaaaacg aaagtaacgg ttatcgacag tgataccact gaccaaggat tatcttttca
     5041 ggtaattcga gcagctgaat tagcaaaaga aggtaaaaca gtagagaaaa tccttgaaga
     5101 agtcaaaaaa gtacaagaca atacaaaatt atacatcgga atatccacac tagataactt
     5161 ggtaaaaggt ggaagaatca gccgaacaac tggtttgctg tctagtgttt tgaacatacg
     5221 cgtggtgatg aatttcgccc attctgaatt aatccctgta actaaggggc gaggaaagaa
     5281 aacgttcgat aaatggttta ataatttgaa aaatgaactg aaagaattgc caaatgtgcg
     5341 acaaatcggt atttcacatg cggatgcaaa agaattggcg caagaattca aagagggttt
     5401 gcaagaatta ttcccggaca tgcatatccc tgtactgcat acgaatccgg ttatcgctac
     5461 gcatactggt aaagacgcgt ttgcaatcat gtattatgta gattagtcga aaagaggata
     5521 agccctcagc ctgaaaggct tgcagcttat tctctttttc tttataaaat taggaaaata
     5581 attgttttct tttttcataa agactacctt tttgataaaa tttttgataa cattagaacc
     5641 aatcgaatac aagaggtgaa aaaatgaaat taacgaaacg acatttgatc ctcgttttgt
     5701 tcccattatt aattgcgatc atcatctatg caggtttagc tgcttctata ccgaaagctg
     5761 gcccactaat gaaaccagta actactgtga gagaagatcc aaataaaaaa gaaaaacttc
     5821 actacatagc tatcggagat tcgctgactg aaggagtagg agatcaaacc aagcaaggag
     5881 gattcgttcc ccttgtcgca aatgatctaa aagaccgtta taatttgacc gcggttgaaa
     5941 cagaaaacta tggtgtaaat ggtgaacgaa gtgaccagat cttaaagcga gtaaaaacaa
     6001 aagaagaaat tcgaaacaat atcaaaacag ctgattttat cacactgact gttggcggta
     6061 atgatttgat gaaagttatc caaaataatt tattcgggtt aacggtcaat tcctttaaaa
     6121 agccactgaa aaactatcag gaaaatgtca cagaactatt ggaagaattt cgatccctca
     6181 ataaaaccgc acctatttac attttaggca tctacaatcc attttatttg aactttcctg
     6241 agatcactga catgcagaca attgttaaca attggaacaa aggaacagaa acggtgacaa
     6301 aaaaaatgcc gaactgctac tttatcccaa tcaatgattt gctttatcaa ggattgaatc
     6361 aggaagtagg tgtcacagaa gaaggaacag atcaaacaac tagcacgaca gaaaatctaa
     6421 atggcatcaa aaataatgtg ctctatgaag aagatcattt ccatccaaat aatttaggtt
     6481 atcaattgat ggcaaatgca gtgagagatc agctgatcga gacacaaaac caatggttag
     6541 agaaggagga tgatcaataa acatgaaaac aagatctgac gtatcttcaa acaaaacaaa
     6601 gaaaacaaat tactggaaat tcgccttcct tatccttctt ggggtagtac ttggttcgac
     6661 cgtattttta ggcagccgta tttttgctaa tcgggaacca gaactcccag aaataccagc
     6721 tcttacggaa agacaaggag atcctgtctt aacgatcaat tcaaataaag aaaaagtcaa
     6781 tcaaatcatc agctttttcc ttagtgagta tcaaaaagat agtgatattg aatataaatt
     6841 ttatttggaa aatgaagcac tactcaatgg tactttcgaa gtactaggtt ttcctatcga
     6901 tttctattta tattttgatc cgtatgtgat ggaaaacgga aatgtccaac taaaagctag
     6961 aagtctttct atcggaacat tgagtttgcc aatcaaagat gtgatgaata tgatcaagag
     7021 aaactataaa ttaccagatt ggatcgaagt caatacagat gatctgacta tcatgcttag
     7081 gttggatcaa ttccgaatgc aaaacgggat gtatattaaa gcagataaaa tcgacttagt
     7141 aaatgatgac attcggttta gtctatattt gccaaaagat acctctgatg cttcaaacaa
     7201 ctcaaatacc aacaaaacta gcaccagcag tactgaaagc aagacaaaag aaaataaaaa
     7261 atcatcggat gagtagtatt agagggggaa tcataatgga acgagcaata tttgcaggag
     7321 gctgcttctg gtgtatgatc cagcctttcg acacgcttcc tggtatccat acagtgatgt
     7381 caggatatac tggagggcat gtaccagatc cgacttatga acaagtaaaa agccaaacga
     7441 ctggacatac agaagcagtg gagattatct atgatccaac attgatttca tatgaacaat
     7501 tagtagaact ttactggcag caaactgatc caactgacgc tttcggacaa ttcgaggatc
     7561 gcggtgacaa ttatcgcccg gtgatctttt atttgacaga agaacagcgg atcattgctg
     7621 aaaaaagtaa gaaacagtta gctgaaagtg gacgtttcga acagccaatc gttacaaaaa
     7681 tcgaaccagc ccaaccattt tatctagcag aagaagacca tcaagagtat tataaaaagc
     7741 atcctgaaaa ttttaaaaga aaccatgcac gccgggctgc ctttatcgaa gaaaattgga
     7801 ggaacgaagg gtgaatcgaa gcttttttca ttatttaatg acactgcgag gcggtggcac
     7861 acatgatgct ttatctgttt tcgctacaga agccggtaaa gacatccaat ttcctaagca
     7921 cagctctagc tacgaagaaa tttctaatta tctggaactg aatgtcgact atttgccgtc
     7981 catggatatc tttgacgaag catgggaaaa atatttagaa aataatcatg acatataaga
     8041 gatagttttg tactttatga tcaaaaaagt tttttgtcca atagcctaat tgaaagaatt
     8101 atttttattt cagctatcta gtcgcatttt tttgatattt ttcttataat aaagaaagaa
     8161 tgaaaaaaag agggatggat tgatagagat tgacaaaaaa acaacgctat attaatcgct
     8221 tctggcttgt attcaaatac ttacttgttt ctgtattcct tgcgttcatg ttgcggggat
     8281 ttttattcat cccggtacca gtggaaggca attcaatgga aaacgtgttg aagcaaggtg
     8341 atatggttgt gatggaaaaa ttttcggaga tcagacgatt tgatattgtt gtttttcaat
     8401 tagcagatgg cacgatttat atcaaacgag taatcggtct tccaggagaa aatgtcagct
     8461 accaaaatga tcaattgaag atcaatggga aagtagttaa ggaaccttat ctaactaaaa
     8521 acctgaaatc agatcatgca aatgcatcct atacgacgga ctttacacta caagagctaa
     8581 cgggacaatc caagcttccg gaagataatt attttgtact tggagataat cgaagagttt
     8641 caaaagatag tcgttcgttt ggcacgatca ataaaactga tattctaggt aaagcaagat
     8701 ttgtctatta tccacttgat gaaataaaat ggatccagtg agaaacaata aagcgtgcag
     8761 tctgttgaga ctgcacgctt tattgtttaa tccaaaatca gtttactacc ttagtacgta
     8821 aaatcaaaca gctcgtttaa acacttttct agcctctaaa gttttgataa atgaataaac
     8881 aaccattatt tgaataggga tttggatcat attcctgatg aatctaccta gaaaaattac
     8941 tttgaaatct gcaccaaaca aaacagacat cagccaagaa ttgataaaaa ggctgactgg
     9001 gatcataatc aataattggg cagcgatgac ggaaggcagg tttatctttt tatgatataa
     9061 aaataagcca ttaataaatc caccaaggaa agccgtgata agaaaagcag cttgaaacgt
     9121 tcctgaacca aatatcgtga aatttaaagt gttcgacaac atttcaagca aaccagccca
     9181 gatcggtcca tatagataac ccataagcgc catacttaaa aatccgaatg tgatttgaaa
     9241 ataagcagga ccaatcgcta tcttgtataa gatgacatca agggctaata aaagagcaga
     9301 ggtcgacaac aatcttgcat tcatttcggg caatctaaaa acgtcttttg caatcaaagt
     9361 gttcaaaata ttctctcctt tgtcagttaa taataaaagg ataccataaa atcaccaatg
     9421 tgtcatgaca cattggtgat ttacatacac tggcatctaa caattaaaaa aagggtgaga
     9481 agactgcttt tataaactgt aaaaaagaga ttgtacgaat aaaaaaaata gaggcggaga
     9541 atacttatcg tatcatccgc ctttgttttt ttgttataaa aaacgtcaga ttagttatct
     9601 gcttacatct tcatccatac gggttctaat gtatttccgt ctagatcttg gacttctaat
     9661 gaaaacatct cttcttcagg cattcccata tctacttcgt ggaaagtacc accattttct
     9721 tttgcaattt gagcaaattt ttttacttca tccgcatttt caacactaaa cgaaatcaaa
     9781 gcaccacttg tttttttatt atcagctatt tctttatctt ttataaattt tttataaaaa
     9841 tcatgagaga gaagcattat ccaaaaagtg tcatcccata ccattgaacc agcttcttca
     9901 gtagaaaatt cttcattttt tttaaaaccc agcttttcat aaaaagcaac ggaacgattg
     9961 acatcagcaa caggaaaatt aacaaaaacc atactattca tttgtttcgt ctcctttctg
    10021 ttttgttcgt ctatcatctc ttatttagga aacgctgtca aaaatttaga ttcatatata
    10081 gaaaccaaaa taaaaatttg catcatcaaa aaagtgaaga tgtgatagaa tgaggactgg
    10141 ttcactttca cttaactaat agatggaatt tctttata
//
LOCUS       DAPBBV010000070        10111 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.072, whole genome shotgun sequence.
ACCESSION   DAPBBV010000070 DAPBBV010000000
VERSION     DAPBBV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.072"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..106)
                     /locus_tag="RD486_002570"
     rRNA            complement(<1..106)
                     /locus_tag="RD486_002570"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(787..2283)
                     /gene="lysS"
                     /locus_tag="RD486_002571"
     CDS             complement(787..2283)
                     /gene="lysS"
                     /locus_tag="RD486_002571"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDT7664278.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2394..3398)
                     /gene="dusB"
                     /locus_tag="RD486_002572"
     CDS             complement(2394..3398)
                     /gene="dusB"
                     /locus_tag="RD486_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDT7664279.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3399..4286)
                     /gene="hslO"
                     /locus_tag="RD486_002573"
     CDS             complement(3399..4286)
                     /gene="hslO"
                     /locus_tag="RD486_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDT7664280.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4503..6614)
                     /gene="ftsH"
                     /locus_tag="RD486_002574"
     CDS             complement(4503..6614)
                     /gene="ftsH"
                     /locus_tag="RD486_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDT7664281.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6704..7249)
                     /gene="hpt"
                     /locus_tag="RD486_002575"
     CDS             complement(6704..7249)
                     /gene="hpt"
                     /locus_tag="RD486_002575"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDT7664282.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(7249..8694)
                     /gene="tilS"
                     /locus_tag="RD486_002576"
     CDS             complement(7249..8694)
                     /gene="tilS"
                     /locus_tag="RD486_002576"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDT7664283.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8814..9284)
                     /locus_tag="RD486_002577"
     CDS             complement(8814..9284)
                     /locus_tag="RD486_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HDT7664284.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9330..9755)
                     /locus_tag="RD486_002578"
     CDS             complement(9330..9755)
                     /locus_tag="RD486_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDT7664285.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9822..10091)
                     /locus_tag="RD486_002579"
     CDS             complement(9822..10091)
                     /locus_tag="RD486_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDT7664286.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
BASE COUNT         2543 a         2228 c         1747 g         3593 t
ORIGIN      
        1 tctttttccg gtggagcaag ctccggtgga aaaagaagcg ttcgacttgc atgtattagg
       61 cacgccgcca gcgttcgtcc tgagccagga tcaaactctc ataaaaagtt cgaacaatct
      121 tgcgattgtt aagctcaatt tgtttgctag catattgctt gcttgttaaa aatgtttgtt
      181 gtcttgaatt gaatcaagac gccctacaca tttggtttgt cttactttgt tcagttttca
      241 aaggtctact tcatcgagag tgtttcccga ttcatttttg gctgccgtag caacttttat
      301 atcatatcag agagacaagc gattgtcaac tcttttttaa aagttttttt cgatttcgtt
      361 tttcgaaatc tttcggcaac tcatttatca taacttatcg tttgttattt gtcaagaact
      421 tttttgaagt ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag
      481 ttatcttatc atgtcgttag taacatgtca ataacttttt tgttatgttt ttgaataaat
      541 attttcttct gtcttttgga caagtaataa tataccaact aaatttagct tggtcaacga
      601 attttttgta ttttttcaag tttttttcaa taaacgatta ttcataactt ttctttcttt
      661 atcgttcgtt ttcgtcttct ttaatgtcta gaatagtcgg cattagcttt tgaactttcg
      721 ttattattta ttcctttcta cacagcaaaa gctgcctaag gaattcctta gacagctttt
      781 attcgattat ctcattgttg ggaatagcaa aacatcccga attgattgtg catcagttag
      841 caacattact aatctgtcga tcccgatgcc tagaccacca gttggcggca taccgtattc
      901 taaggcttcc aagaagtctt cgtctacacc gtgagcttcg tcatttccta gttcacgttc
      961 tttttcttgc gcttcgaatc tttctctttg atcaattgga tcgttcagtt ctgtaaaggc
     1021 attagcaaat tcgcgcccca ctatgaatag ttcgaatcga tctgtgaatc gaggatcttc
     1081 tggatttttc ttcgctaaag gcgaaacttc gactggatgt ccgtatacaa acgtcggttg
     1141 tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg ataacatgtc cgacacccat
     1201 agcttcggtt acttctacat tgtgtttttc ggctaaagct aatgcttctt ccaatgtcat
     1261 ttcttgccag aagtctacac cagtttgttc tttgattgca tctaccatat ggatgcgttt
     1321 aaagtcactt tctaagtcga cagcttgtcc atcatatgtg atttttgctg ttcctagtac
     1381 tttttcagct gcgttacgga taataccttc tgtcagattc attacatcat tgaaatcagt
     1441 atatgctgtg tatgcttcta acatcgtaaa ttctggatta tgtgtagtat caattccttc
     1501 attacggaaa acgcggccga tttcataaac tttttccatt ccgccaacaa ttagtcgttt
     1561 taaatgaagt tctagcgcaa tacgcaaata taaatcaatg tccagtgcat tatgatgcgt
     1621 gataaatggg cgtgcggcag ctccacctgc ctcattgtgc aatactggtg tttctacttc
     1681 aatatagcca ttgccatcta aatagcgacg gatttcgctg ataatttggc ttcgtttcat
     1741 aaatcggtca aagctttcgc gattactgat taaatccaag tagcgttgtc tgtagcgttg
     1801 ttcaatattc gttaagccat ggtatttatc tggcagtgga cgaagtgctt ttgacaaaat
     1861 cgtgatttct gaagctttga tagaaacttc gcctgtgtct gttttcatga tttgtccagt
     1921 tacaccaaag aaatctccaa ggtctgcatg tttgaatact tcataggcct catcacctac
     1981 ttggtctttt cttacataaa tttgaatttg gccttcacga tcttgtagat gcgcaaatcc
     2041 agctttccct tttcctcggc gagtcatcat acgaccagct acactagcgg tcaatcccat
     2101 ttctgctagt tcttcttttg ttcttggatc aaatagttca tgcaattctt ctgagttgtg
     2161 cgtgcgttca aatcgttttc caaatggatc gattccatct tcacgcaatt gttccatttt
     2221 ttgacgacgt acaagcattt gatcatttaa atcttctact tgatgttgtt gttcctgtgt
     2281 cacaaaagtt cctccattct catgttaatc tctttcctat aatgccaatg aaacacaaaa
     2341 aaagcaagcc gaacttggaa tttcggcttg aaaattcacg aaaaacttag aaatcacaac
     2401 gtttgtttca atagtacttt ttccgctttt tctacaaatt gatccagcag gtcattgatt
     2461 tcttgctgtt tttctgtctg attgattgct actttcactt tcgctgctcg aggaatccct
     2521 tttaaataat aagccgcatg tgttctgaat tctctacaag ctactttttc tcctttgaga
     2581 tctgctaagc gttgtaaatg aagtttagct gtagcaattt tttcggctgg tgttggttca
     2641 ggaatcagtt ctcctgtttc gagataatgc tgtgtgcggt gaatcatcca tggattgccc
     2701 agcgctgcac gaccaatcat cacaccgtct gcaccgacat agtcaagcat ccattttgca
     2761 tcttctggcg ttttgacatc cccgttcccc ataaatggga tcgtcaaatg ttttttcact
     2821 tctttcaata cttcccagtc cgcttttcct tcatacatct gaacccgtgt acgtccatgc
     2881 atagcgatgg cacttgctcc agctgattgt gctgctaatg cattttctac agcaaagacg
     2941 tgctcttcat cccaaccaat acgcatcttg attgttactg ggatatttac tgctgaagaa
     3001 acagcttgga ccatttcgta tactttctca ggatctaaaa gccattttgc tcctgcttct
     3061 gctttgatta ctttatttac tggacagccc atattgatat ctattatatc ggcagctgtg
     3121 ttttcttcga caaattgagc agcttcaact agactatctt tatttccgcc aaatatctgt
     3181 aaacttaatg gatgttctgt ttcttcaatg tggagcatct ctaaagtttt tttgtttctg
     3241 aaatgaatac cttggtcact gatcatttca catacgacta agcccgcacc aaattctttg
     3301 acagtgactc gaaatgctga atttgttatt ccagccatcg gtgcaacaac gacacgatta
     3361 gggatttcca cattgccaat tttccatgtg tgttccactt aaatccctcc taaggcttct
     3421 ttcttcaatc catctaattc ttcttcgcta tacttgtatt tgttattaca gaaagaacaa
     3481 accgcttctg caccgtgatc ttcgtctatc attgcttgga tttcttctgc acctaacgcg
     3541 ataattgctt ctgcaaattt ttcttttgaa cagtcacatt tgaattgaac aggcattttt
     3601 tccaaaatgt tcaattcttc tgtaccaagc aatcctttca atatttcttc tggtgtctgt
     3661 ccttcatcta agagggtaga gattcttggt gtcgttttta attgttcttc gatcttgctg
     3721 attgtttctt catcggcacc tggcatgatt tggatcatga atcctcccgc cgtcttgatg
     3781 ctgtcgtcag tattgaccaa tacactcagt ccaacagctg aagggatttg ttctgagata
     3841 gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa caatcggcgt ttgcccagaa
     3901 aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca ttccttgtgt tccaactgct
     3961 ccccgcacat cgattttacc ttcactattt agaggaagac tgagatgcgg atttttgatg
     4021 taacctttca catctccctt tccatttgca tctactacaa ttcctgttgc tggaccatcg
     4081 ccttggattc gaacagttag tttgtcttct cctttgagcg tcgcaccaag tagcagacta
     4141 ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc aagtatcatg acgtctttgt
     4201 gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc ggacgaatcc gtcgtgagca
     4261 agtgccttaa ccaaataatc tttcatttgt tatgtactcc tttttccgtt tttaaactca
     4321 tagtgaatca tactagcaac tactgctttt ttcaacttgg gaatgcttct tttaaaaata
     4381 attcagaatc atctagaaaa caggacatca ccctatttac aacttaaata aagaaatctc
     4441 ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc agatcaattg acctatattt
     4501 ttttatttgt attgatcgtc tgaatgatta tcttctgatt gttgagaatc tgaatcatgt
     4561 tctgctttat tttcctcatt cagttcatgt tttgcttctt caaaatcacg tttttcttcc
     4621 gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg cttcttcaaa agttttcgct
     4681 tctttttcgc ttggataatc atttgactca gtaccttcag gcatcacacc gtgttcaaac
     4741 aatgacttga ttgctttggc atccaatgtt tcgaattcca aaagtttttc agcaatcagt
     4801 ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt tatcatgagc ttccatcaag
     4861 atttttcgta cttcttgatc aatctcgaaa gcgacttgtt ccgagtaagc ttttgtttga
     4921 ccatagtcgc ggccaacaaa cacttgatgg tttccttcat attgaacagg acctaaacga
     4981 tcactcattc catattctgt taccatgctt cgtgctagag ctgtcgcttg ctcaaagtca
     5041 ttggaagcac cagttgattg gacattgaag atgatttctt cagctgtacg tccaccaagt
     5101 aagcctacga tttgttcaaa catatcttct ttcgtcatca agaactgatc ttcttttggt
     5161 aaagcgatca tatatccgcc ggcgcgtccg cgagggatga tcgttacttt gtggacgacc
     5221 cgagcgcgac tcaatactaa tccgacaatc gtatgaccag cttcgtgata agcaaccatt
     5281 tcgcgttctt ttttgctgat tacgcgatct tttttagctg gacctgcaat cacgcgatct
     5341 tccgcttcat cgatatcaga agcatcgatt ttctttttat ttcttctagc agctactaac
     5401 gctgcttcat tcaagacatt ttctaaatct gctccggcaa aacctggtgt ctgttgagcc
     5461 acaactttca agtcaacgtc atctgccatc ggtttattcc gtgcatggac tcgcaagatt
     5521 gcttcacgac cttttacatc tggacgtcca actaaaatct ggcggtcaaa acggcctgga
     5581 cgtagtaacg ctgggtctag tacatcagaa cggttggttg cagcaatgac gattactcct
     5641 tcatttccgt cgaagccatc catttctaca agcaattggt tcaatgtttg ttcgcgttca
     5701 tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta ccgcatcaat ttcatcaatg
     5761 aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca aatcacgaac acgacttgct
     5821 ccaacaccga caaacatttc tacgaaatca gaacccgaga tcgagtaaaa cggtactcca
     5881 gcttctccgg caacagcttt tgctaataag gttttacctg ttcctggagg tccttctaaa
     5941 agtacacctg ccgggatacg ggcacctaat tcaacaaatc ggcgaggatc tttcagaaat
     6001 tcaacaactt caactagttc ttgtttttct tcttccgcac ccgctacatc agaaaaacgt
     6061 acgcgattag cttttttgtc tgcttctttg gcttttgatt taccaaagtt catgacacgg
     6121 ccgccaccgc caccgccgcc gccttgttgt cccatcatca tgtaaaagaa aaagatgatg
     6181 attacgattg gcaagaagct aagcaatagg gaaacccata taccgctgct tgattcttct
     6241 tttactgttg tagcaacttt gttttctttt gccagttctg ttacttggct caatgttgta
     6301 tcatttggca aaatgattgt tgtgaaatgg gtagtagtcg tatctgttga acctaagata
     6361 gctaacccac cgctgttagc gacggtctgc tgttctttgt attcaccagt gatcttatat
     6421 acaccatttg caggctgcac ttcaaattct ttgatcttgc ctgcttgtag ttgttctgtg
     6481 aattttgagt actcgatatc tgacgatcgc tggccgttat taccaaaaat gaaataaacg
     6541 accattacca tcgctaagat tacgaggaca taatacaagg catttttcat catgccgttg
     6601 ttctttttgt tcatagttgc cctccctaag cgtcaattta atttaacagt tttttatcaa
     6661 tcctgaccat tctattgtac cataatttaa ttgagataca gcattaattt gattgataaa
     6721 cactaggttt caatacaccg atgtacggaa ggttacgata tgcttctgca taatccaagc
     6781 cataaccgac cacaaattca tttggtacgt tgaagccaac ataatctgct tcgatattta
     6841 ctactcttcc ttcaggtttg tcaagtagtg taacaatttt gactgatttt gctttgcggt
     6901 atttgaaaag atccactaaa taagcaagtg ttcttccgct gtcaatgata tcttcaacga
     6961 tcaacagatc gcgaccttct acattcgtat ctaagtcttt gacgattttt acttcccctg
     7021 acgagactgt tgcattcccg tagcttgaaa catccatgaa atccaattcc aaatacgtat
     7081 cgatagaacg aacgatatct gccatgaatg gtaccgctcc ttttaagaca cctactacta
     7141 ggggattggt gttttggtaa atttctgtta actctttgcc tagttctttg caacgaactt
     7201 gtatctcttc ttgtgagatc aaaattctct caatatcctt ttccaacatc aggttctcct
     7261 tccaattgct tctttttgat atttgtaaag aagtatgtag tgtattttat cagtttcttc
     7321 acgaatactc aaatatgaaa aggcaaaagg tatcaagcta tatatatttc ttttggcatc
     7381 tgtaatgatc caagcatgct gcctttgtga attaggtact ttctgatcga taaaatatct
     7441 agatactttt tttgtgagat tctctgttaa tttaatgcgg tctcctgctt ttcttttttc
     7501 gacatacagt tgcacatcag caggaatcca aatgtcatga gaaaatagag accatgaatc
     7561 tgttgctttg atgtcccctg cattttcagg tttgaccaga ccaatccatt ctgtttcatt
     7621 caaatatatt ccttgttctg gaatcagcaa caagcgctgg tcttctgtct ggctagttgc
     7681 ttgtttttct tttttagaga gtacaacaaa atgatactct cttttcagta tccaattatt
     7741 gccaatactg agttgccatt ggcttttttt ctgttgccac tggtctaaaa tcgactccat
     7801 ttgttgttct ttcaaaataa ttcctgtttt tgagaatgct ttgtcgaaaa aggagtaaaa
     7861 aaaatagtat cgttcagcat ctgtcatttc ttcaatcatt tctgcagaaa atcgaaattg
     7921 ttcctcccac tgttcgactt ccttttcgat caactgtccc atatattttt gaatgacttg
     7981 gtctgcccat tggatctgtt gcgaaaattg ctggaaatgt ctcaacgcct gtgtattttc
     8041 ttgtttcaat tgaggaacta ccaaatgacg aagccgattt ctctggatat ctaacaattg
     8101 gtttgtctga tcctcaaagt aaacaagctg cgattccgct gcataagtat ataggtcttc
     8161 tttgctaaaa ctcagcaacg gacgaatcag tctgcccgta gcaaatggtt gtacttcttt
     8221 gattccagaa aaagtattta actgtccccc acgaacgatt ttcattaaca ccgtctcgat
     8281 ttgatcatct ccgtgatgag cagtcatcaa cgtgtcatat tgtccttctt ccatcacgcg
     8341 agtgaattct tgataacgaa agttacgagc ttctgtttct atggcggatt tggctggatc
     8401 ttcccaaata cttacatata aagggagatt cttctcttca caatatgagc gaagataggc
     8461 agcttcttct gctgattctt ctcttaattg gtgattgatg tggacgatac ctaaagaaaa
     8521 accgatttgg cgttgcactt gtaaaagtaa atggagcaaa accatcgaat caacaccacc
     8581 tgataccgct gctaaaattc tcgatccttg ttgccagaat ccttgttcat tcccgtgccg
     8641 aataaatgac tgctgtaata gcggtgcttt tttcccgcct ttttcaacgt tcatcctttc
     8701 cacacccttt cttcctaaaa aaaagagagc gggaaaacgt ctaaaacgac aattaacctg
     8761 ccctctgttg atactatgac ccaaatagtc gcactatcat tatttgcggc tttttagctg
     8821 cgacgtccgc cacggccacc gcgctttcct tctgtgtttc gcttcaatga agataagcgg
     8881 tcatcgctat ctttcaaaaa tgaactcatc aatgaatcga agtcttcttt ttgagctgaa
     8941 ggttgactgc gagaaaaaga ttttttctgt gctggacgat ttcggttgtc acggggatct
     9001 ttttgttgat attttttagg acggctttct tctccagatt cagcaggttg ttcctgcgct
     9061 ttccggatag atagtccgat ttttccatca tcatttactg aaataacttt aactgttact
     9121 tcatctccta cacttaaaac atcatggatg tcttttacat agccatttga cacttcgcta
     9181 atatgaacta gacccgtttt tccagcacct agatcaataa acgcaccaaa atttgtgatt
     9241 cctgatactt ttccttgcag ttttgctcct acctcgattg acataaaaaa aatgttcctc
     9301 ctaattattt ccctttttta tattcctgct tattttgcag ttgtagaact agttgattga
     9361 tctgtttcat ttgtcgagct gtctgtattt gattctaata taggataaac tttttcaccg
     9421 tcttttgagt aaaagaattt gcttctggca agtttagcta catactcatc atctttcagc
     9481 aatgaaacat cttggtgcag ctgatcaacg tctgcgttga cttctttcat ttcagtattt
     9541 gcttcgactc tcaattcgtt caattgatgc atcctttgca tgtcatggaa aatctgcaca
     9601 cctattatcg cgaaaatgac caaagcacca acaaaaattg cagccagtct gcgtcttcga
     9661 aaaatcagtt gacgttgttg ttgctgaaat tcagcatact ttttctttgc atattccgta
     9721 tctagcgcag cgattttatt gctttttttc gtcacttgga ttcgctccaa tctttttgat
     9781 tgtctttttc attataccaa tatcgtgaaa gcttgtctaa tctatttctc tagtgtttct
     9841 gtgcgatttt cagaaataat ttcgtacatt ttttgtgcat cttctttttt ggttgattca
     9901 tgtaattccg taattttcac ttccaacgtt ttgttgccaa actggacttt caaaatatcg
     9961 cctactttga catcactgga agatttcgcc aatttaccgt tgatttgaat tcttccttta
    10021 tcagctactt cttttgctac tgatcgtctt ttgatgattc gggaaatttt taaaaattta
    10081 tctaatcgca tatcttattc ctcacttttt a
//
LOCUS       DAPBBV010000071         9935 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.073, whole genome shotgun sequence.
ACCESSION   DAPBBV010000071 DAPBBV010000000
VERSION     DAPBBV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.073"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            157..1548
                     /locus_tag="RD486_002580"
     CDS             157..1548
                     /locus_tag="RD486_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7664287.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(1621..2268)
                     /locus_tag="RD486_002581"
     CDS             complement(1621..2268)
                     /locus_tag="RD486_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDT7664288.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(2276..2962)
                     /locus_tag="RD486_002582"
     CDS             complement(2276..2962)
                     /locus_tag="RD486_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7664289.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(2968..4041)
                     /locus_tag="RD486_002583"
     CDS             complement(2968..4041)
                     /locus_tag="RD486_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7664290.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            4263..4937
                     /locus_tag="RD486_002584"
     CDS             4263..4937
                     /locus_tag="RD486_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7664291.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            4942..6282
                     /locus_tag="RD486_002585"
     CDS             4942..6282
                     /locus_tag="RD486_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7664292.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(6431..7417)
                     /locus_tag="RD486_002586"
     CDS             complement(6431..7417)
                     /locus_tag="RD486_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HDT7664293.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            8141..9172
                     /locus_tag="RD486_002587"
     CDS             8141..9172
                     /locus_tag="RD486_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7664294.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            9281..9706
                     /locus_tag="RD486_002588"
                     /pseudo
     CDS             9281..9706
                     /locus_tag="RD486_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
     gene            9819..>9935
                     /locus_tag="RD486_002589"
     CDS             9819..>9935
                     /locus_tag="RD486_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HDT7664295.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNR"
BASE COUNT         3210 a         1795 c         1704 g         3226 t
ORIGIN      
        1 attatacgaa gggcgctaaa gggaatcaca ccaattttca taccaattgg tttcatttat
       61 gaagttgatt ccttcgatta atgagcgttt cattgaaaga aaagggttga gggagaaaaa
      121 catatgatca ggttgttgga atgaaactat agaaagatgg aaaaaatcat tcgaattctg
      181 tccatttctg acaagtggat gactaaaaaa gaacttgcca aacgaattgg tagttcagaa
      241 tctacatttg taaggtatat cgaagagatc aaaatccgct ggggaacgga tgtaacgatt
      301 caatcttcac aaaaattggg gtatcgtctt gaacatttga atgtaccagc ttatttaaat
      361 gttctgatgg aaatgtcgca aagttctaca aacagtcgtt tattaaatga gattattgtc
      421 aatccgggta aaacgattga gtattattgt gaaaaaattt ccatcagccg gtcttctttt
      481 acacgtaagt tgaaacaatg caatcaaatt ttagaaagct atttattaaa agtgatcgtt
      541 gaccaaggtt ttcagttaac tagccttaaa agtgagctcc agttgcgtat ctttgttacc
      601 tttttctttt taagttacta cggaagacgc acgttgccat ttccaatcga aaaaaagaag
      661 atcaaagaaa ttatggtcaa gaataattgt cagatgaatt tgtttcagga agaaagccca
      721 tatgagcaat ctttctttat tatgtatttt gttgtgcatc tcatgagaga atcccaagga
      781 actccatttg aatggaaagc tggagactct tatgtacagt tgataaatat cgataaaaaa
      841 gacttcttaa tcttgaaaaa tctcttagga aaattgaagt acagcagcta tataaaagta
      901 gtgaactatt ttgtcaatac gattttttca gaattttcgg agaaagaaaa aaatgaaatc
      961 agtgagcaga tacgaaaaaa tatgtcctac tgttcgtttt catccgctga ttgcaaagaa
     1021 aaaaacgaag aatatgttgt tcaattatta acgcaaattt attttttctc ccgtattttc
     1081 ccatacgata cgactcattt gacgatccgt gcaacttact ttgcacagca gatgcaacac
     1141 cgccagatac gtctatatgc tggatttcgt gcagaacttc aattttattc cactctactg
     1201 aatcagaatc tgatttatta tttatctagc tatatctttt ggatgcttat cggtaatcct
     1261 gaaattcacc attatacttc tgataaaaaa atactgatta tcagcgactt aagtcttcga
     1321 catagtcaat atattgaaga atatatcagt gatattcttg ctgtgcataa aattcactct
     1381 gagacaactg ctattactga agatcagctg tcgaaataca atcttctcga gtatgatctg
     1441 atcgttacga atcaacccat tttgaatgcc catgttcctc atatattgat tgatgatagt
     1501 gtgtcattcg caaatgaaga agaactcatc cgcttattcg agttatgaat aatcaaaaaa
     1561 cagctatgta taaaccaccc tgataaaaat ttcaggacaa atacacatag ctgtttcttt
     1621 ttattgtatt ccttcagcaa tccaacgaga tttatagcga aagtctttta acaactcttc
     1681 ttttgtccaa ttatttgcaa tgagatccgt caaagtgttc attacgaggg tcatggaaaa
     1741 gtataggaaa ctaactgctt cttccgacga ttgaatggag aaatgattga ttcttaataa
     1801 ttccagccat ttttcgttca ttggagaatc agccgatagt tctctacgtt tggttgtctg
     1861 ctgatcattt cgctgggtta acaagtataa cctttgccaa tagatacttt cgtgatctaa
     1921 gtcgcagcac cactctaaat atttttcgat ccccaaaaag aaatgttgtt tgttttcgct
     1981 aatgaatttt aagatatctt gatggactat gtgagaactg cttttgatcg tatacaaata
     2041 agcatcttcc aaatcttgaa aatatttata aaaagcaccg cgcgacatcc ccatcttgtc
     2101 aacgatttct gagactttga cttggctgat gtgctgtgag caaaatatct ccagtaatag
     2161 gtcatcgatt ctctgtttct ttgcgttcga taaattgaaa aaagtttctt ttggcatcca
     2221 catctctcct ttatctctga ttatacgtgg atagcccttc attgtcatga aggattcatt
     2281 ccttcttttt ctcttcttct gtcaagtacc catcttccat tcgataaacg cgatcactcc
     2341 attgaatcat acggacatca tgagtaacca taatagtcgc tttttgtttc tcatgagctt
     2401 ctttaactag taatttgacg acttcatatg catgatctgt atccaaacta gctgttggtt
     2461 cgtctgctaa gatcaagctt ggctcattat ataaagcgcg agcaattgcc actctctgtc
     2521 tttctccacc agaaaggtct ttaggataac tatttttaag tgactggata tctaaagatt
     2581 gcagcaagga atcgattttt gttgaatctt ctttttttga agtaacttgg tcaactagtt
     2641 caaattgttc ctttaccgtt aaaaaaggaa tcaaattaga gctttggaga ataaatccta
     2701 tttctttaaa gcgtaaatct gctcgttttt tttctggaag ctcagttagt gagtgaccgt
     2761 tgatcactat ttctccggaa gtcggtgttt gcaatcctcc tgaaatggta aggaaagtac
     2821 ttttacctga accagaagga ccaatgatgc tgacgaattc tccttccttt acataaaaat
     2881 caattgcttt caaagctgag acctttgtat gaccagaacc aaatgttttg gtaacttttt
     2941 tcatcgttaa tatttttttc atttttatta acctcctatt gctgtaattg ggtctacttt
     3001 ggttatcgta cgtatcgaaa acaatccgcc tagcattgcg acaatgatca aaatcccact
     3061 atatagcaac cattgtgacc aaaaaacagc aaaaggcatc gcgcttggta aaatcagact
     3121 agtcaaataa gcaaacaaaa gagcaagcag aacgcctacc accccaacaa taaaggactg
     3181 tgctactaaa gatttagcga tgaagaaatt tttgatccct tgtgctttca ttactccaaa
     3241 aatagcagtc ttctgaagtg tcatcacgta catgaaaata ccgaccacgg cagcaaccac
     3301 taagaacaaa aagtatatca tcgcatttaa ggtcatattt tgggcagaat agccaggaat
     3361 actttcaatg aatgtcccaa tagttaataa ctgtagaccc ttcgatgctt tttctttcga
     3421 aattttagct gaatccttta ttacgatccc attgatcggc tgttcttctt cagaagcaaa
     3481 cggctgttgt ccatacttca aagcagtcca cgtatctagg gacgcataga tgacgggaga
     3541 aactgtgtaa taagtttcag gaaagatacc gacaatcgtc aaaggatcgt cgtaactgcc
     3601 aattttgatc gtatctccaa ttttatagcc tgaatcagcc agattttgag agatgatgat
     3661 ttcattcttt gttttaaatt catgcccttt cgtgagtttt ggtaataaaa atgcttcttt
     3721 cgttgtgccg aaaactgtaa cattttcttt gttttttcct ttgattgctc cgctgtacaa
     3781 tccgattggt gctttctctc ctccttcaat gtatttcaga tctcctcttg ttaattgtga
     3841 agctgcaaat acttgatttg catcctccga caaaacaatc tcttgtgcgt cccaatcatc
     3901 gattgctttt ttaaactctt ctgaaagtcc attcgctagt cctgacaaca tgaatacgac
     3961 atacgcaatc aagaacataa taccgacgat caagccatat cgtaatttag aatagcgaat
     4021 ttctttgata gctagaaaca tttgtttttc ctccctatga tagattgata gtgacaaaat
     4081 gtcacttgtt gaatagtgta actctaaagt gacaatttgt cacttgtgtt gtttttttct
     4141 tatcaataaa ttgtctaaga catctttcga taaaacctta acatgagtca taaaaaattt
     4201 atttaagcct tatttatgct ttccatgata aactaaagtg accaaatcaa tgaggtggga
     4261 aaatgattaa actattagta gtagaagacg ataaagtatt atccaataat ataaaagaaa
     4321 tactcgctgc aatcggcgag ataacacaag tttatgatgg tagtgaagga ctgttcgagt
     4381 tggaaagtgg agtttatgat cttgcaatct tggatttgat gatgccggaa atgaatggat
     4441 atgaagtgtt agcaaaaata cggaaagaaa aaatacagac tccagtattg attttgactg
     4501 caaaagatag tttggaagat aagattgaag gatttgaacg aggtgcagat gattatctaa
     4561 caaaaccttt ctatcgagaa gaactgatca tgcgcgtgaa agcattattg aaacgctcgc
     4621 taggtctctt tgatgaaaat gttctgaagt ataaggatat cagttgtgat ttaaaaagca
     4681 atgaagtctt gtataaagaa caagttttgc ccatacaagg aaaagagttt gaattgctcg
     4741 tttatttttt acaaaataag ggaatcattt tgacaaaaga gcagatattt gaccggatct
     4801 ggggatttga ttctgatacg acgattacag ttattgaagt ttatatgagc aacttacgaa
     4861 aacatctgcg aagtactgga ttggataaag aaatcaaaac cttacgtaat gtcggttata
     4921 tactgcaaag ggtgtgatgc aatgaatgga gatattacac gaaagcaacg tagtcgcttt
     4981 tttgcgacaa atgtagcagc atttgctttt atcttttttc ttttgggatt cattacttta
     5041 cagatattaa accaatctgc atacagagaa acagatctgt cattagagaa aataaatttt
     5101 gattctcgaa cagtacaatt agagatacaa agatatcagc aaggcgatcc ctttttaaac
     5161 ccgactcaaa cggaacaaaa cagaacaaac atggaacagc cattaatgga accatcaaat
     5221 gaccgtttta acactcaagt gatcttgtgg tctaaaaatg gtgagatatt gaataaagca
     5281 gctattggtg ggcgtttcaa ccaaatcaaa gaattaaaaa tggatacgaa aaatctgaat
     5341 accatccaaa atattgaatt aaatgaagac agtggctcat ctgccctctc tttccgttcg
     5401 attacgaaaa aagcggagac gaatcaagat ggcgttgcct acatccaaat tttagaaaat
     5461 acaaatcaaa tcaagaattc attagcgact tttcgcacga ttatgatttt gtgtatgatt
     5521 gttttttgga ttctctctat tggtatcagt tattacttgt ctagtctaag catgcgccct
     5581 attattcttt cttggagaag acaaaaagaa tttgttgaga atgcttctca tgaattgcgc
     5641 acaccgttaa cgattattca aaatagtttg gaacatcttt ttaccaagcc taatcatact
     5701 attattgaag aatccgaaag catcgctcaa gcattgtcag agacgaggcg cctcactgga
     5761 ttgacttcgg atttgctgac aatcgctcgg aatgattctg atcagcagct gctttcaaag
     5821 caaatgatca atacacaaga atatatcgaa caacttgtta aaccatttca agagatggcc
     5881 atcatagatg gaaaagagtt tattctccat aacgatgcaa cattagaagt accaattgat
     5941 gaaaaaaaaa tccatcaagt tttggttatt ttgctggata atgcattaaa atatacgaat
     6001 ccagaagata agatcatttt ggattcatct gttaaccata aagaatggct gattcacgta
     6061 aagaatactg gcccttctat cagtgaagaa gatcaagcaa ggatttttga tcgattttat
     6121 cgggaagatc aatctcgggc gaaagagact ggcggatacg ggcttggctt ggcaattgca
     6181 aaacaggtaa tcgaacagca tcatggacag atttctgtat ccaattatct tccacaagga
     6241 gtcgatttta aagtccaatt gccgttgaag cctaaaaaat aatgcttatc cctaaaaaag
     6301 ggctgtgaca aaaatcttgt cacagccctt ttttgttgcg aataaacggt gttccagaag
     6361 tagcttcttc ggaaataagc cgaaatttct ttaagctgac cacttctgtc acaacctctt
     6421 tagcttacgc ttacgatttt ttattgcggt cttcaatgtg tacatcaccg cttgtgtcaa
     6481 tatccaattc ttctcggcta acatcttctg tcactttttc aacatcttca tgttcttctt
     6541 tatgaatccc aacttcttca cgaataactg tatgtttgct tacatctact tgctcttctt
     6601 tgattgggat agtaatcgtg tcatcttcca atttttcgtc tgttccctgt gaagattgat
     6661 ctgttactgg tttgcgttcg atgacgattt cttcacgttt gaccggtact tctaccgttt
     6721 cagtatcgtt gaccacatgt ttgtggatgt cgacttctcc agttgtcaca tcatgtgtat
     6781 ttacatctaa tttttcttct tttagttgaa ttgtatcatc atctagattt ggtttgcgat
     6841 cgatgtcttc agtcttgctt gtacccattg tatcagtctc gccaggtacg tccatcggat
     6901 cagttcctgg tgtcatattc aatggatccg ttgtattttg aaagcctgtc gtgccaccta
     6961 cgtccattgg atctgttcca gtgccagttt ctaatccagt ccccattgtg cttgctgggc
     7021 taacagtatc ttgtgtatcc attgtatctt ctgttgtttc tggctgacga tagcctttta
     7081 ctgtgatgac aaattttcca tcagaaatat ctcctctata ttgatataaa ggatcatttt
     7141 ctggtgtagc cgtctcagaa tcataggtat caaaagaaaa agtatctttt attttttccc
     7201 ataaagaacg gtcttcttca ccatccatcc gattttcatc tgtttcaaca tctataccag
     7261 acaatccgtc aaatcctagt ctagatgctg cttcatcagt agtataaata acgatatcat
     7321 ctcgttcata cccttcgtta cgcaaccgtt caattactga taatgcttct tccctcgtac
     7381 tatagcttcc gatgaccgtt aaatttttct cttccatgta aattcctcct agcaaataga
     7441 tttatgattg gtatattgtt acttataaat ttattctata ggagacgatt gttttctaca
     7501 aatatttaga ttggaatttg attaaaacaa tttaattgaa atttgaaaac atttatgtta
     7561 atgaaagtca tattctaata aaatgtcatt tgtttctata tgaattttta tgaaaaattt
     7621 catataattt ccactcgttg tgatggttta atttatccaa tccatcaata agcaaacaac
     7681 ttatataaaa aaggattaat tctcaatata attgctccta ccatagaata aatcttcatg
     7741 taaagtaatg aagtaccaac tatttctaat acttctttaa gaattatccc aacaatatcg
     7801 ttagacaaac cattattgaa taaatggaga gccaatcgat tctgaaaaaa tgttttctaa
     7861 tttttcggaa ataaaagaaa gagcctcctg ccattagaac gaaccaaatc catttcattg
     7921 ctcatgaagt aaccacatag ctaaaaagag gataaatcaa ttaaaagatc aaaagaatga
     7981 ctgcactaat aaaataacta aaaatgtatc ttcttacttc atatctttta gctagtactt
     8041 agttaaaaat ttgcttccta agatcaagac aaactgtcta tcttcatttg atgaaatgcg
     8101 gtaaaatata gaaaatgaac actattggag ggaatttgta atggacagca aaactagaaa
     8161 acaactgcaa gaaaagttaa agcaacgtac acacttgctc ccttccgtct ttcaacagtt
     8221 tttagaagaa aatcgttctt ccctttcatt aggcagtcgc tatgaatacg caaaagattt
     8281 tcatctgttt actgattatt tgagaaaagt attttctgaa gaagtggatg atcagctgat
     8341 tatccattta gaaaaacaag attatcagaa tttcttagct aaaatctatc gacatactcg
     8401 ttcgttccaa actacagcga accaagaaac ggagcaattg tttgaaaata gctattacgg
     8461 gatttcaagg aagcaatatt cattaaatca ttttttacga tttttgtatc aaaaaggact
     8521 gattgaagaa gagatttctc ttttgggtac aagtttaccg gaaacaacca aagcagctcc
     8581 gcgatatatc gatgcagaac ttttcaaaga ttttgagcat ttgtttatcc cgattgaagg
     8641 ctttcaaaca agcagagaag ctagctttga agaaaagaat agaccgagga accttgcaat
     8701 tactgccatt cttctgtatt gcggattaaa gatccatgaa gtagtagaac ttaaacgtaa
     8761 agatgtatct ttgaccaagc agattcttaa tctgaataga aaagaaaaca gactgaataa
     8821 agtaccaata ccaaaagaag cgatgccatt tctggagaac tattttaagt taacagcaca
     8881 aaatacggac gaaaattctt ttgtttttcg ttcctcacat gatcagcaaa tttctcctcg
     8941 gactattcgc caaattttga gcaaaattac agtatataaa aacgtatcgc cagaactatg
     9001 cagaaaaaca tatcgttatt atgcagaact atatttagat gatgctgacg cggtaaatta
     9061 tttatgtggt aatcgatacc tctcatccca ttcttttcaa gatatctggg aaaagatggt
     9121 tgatttttct tatcacgaat tagcggcatt cgttcgggtt tcttccatat aaaacaaatg
     9181 tatgatcttt ttttcacaat aaactatgtt attatataaa ggattatgtt acgattatct
     9241 tgaatttgta tattacttaa caaaagataa tggagtgtga atgatggaga ccataacgta
     9301 ttcccctttg aacttattta cgaattttca agaagctgca gctaactttt ccgagacccc
     9361 gattatcttt gatgagccac tttcagcttt cccagaatta ggacttgaaa caacttacaa
     9421 aaaatgctgc gaaagtgtgt tgaaacgggc ttatcaattg gctcatcttg gagtgaaatc
     9481 cggagacaaa gttattattt ataagagttc cgcttttgac acataccttc tagctgtttc
     9541 tgtgtcttac cttggtgcag tgcctgtcat gacttcttat catctaccaa caacaacaat
     9601 ggaagtattt atcgatcgtt tagaagaccc tttcatttta tttgatgatg agacaaaaaa
     9661 gcgagtgaga gaaatttcaa atggaacaaa atcaaaacag attcctaacc cgtggtgcta
     9721 gttaattttt tcctagagga aaatgtctaa acatgttggt aaatcaacaa aaaaacgcat
     9781 atagtagtct caaaactccc aagaaatgag gactacatat gcgttcatca aaatatactg
     9841 aacattatac agatactttt ataacattca aggaaattat gagaactgtt tctaacatat
     9901 accacaattg tgtaccagat aagattaaaa accga
//
LOCUS       DAPBBV010000072         9819 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.074, whole genome shotgun sequence.
ACCESSION   DAPBBV010000072 DAPBBV010000000
VERSION     DAPBBV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.074"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            52..504
                     /locus_tag="RD486_002590"
     CDS             52..504
                     /locus_tag="RD486_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664296.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            518..1207
                     /locus_tag="RD486_002591"
     CDS             518..1207
                     /locus_tag="RD486_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664297.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1332..3683
                     /locus_tag="RD486_002592"
     CDS             1332..3683
                     /locus_tag="RD486_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HDT7664298.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3763..4158
                     /locus_tag="RD486_002593"
     CDS             3763..4158
                     /locus_tag="RD486_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664299.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4483..5100
                     /locus_tag="RD486_002594"
     CDS             4483..5100
                     /locus_tag="RD486_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7664300.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5141..5440
                     /locus_tag="RD486_002595"
     CDS             5141..5440
                     /locus_tag="RD486_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HDT7664301.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5474..5641
                     /locus_tag="RD486_002596"
     CDS             5474..5641
                     /locus_tag="RD486_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7664302.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5686..6291)
                     /locus_tag="RD486_002597"
     CDS             complement(5686..6291)
                     /locus_tag="RD486_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7664303.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            6416..9403
                     /locus_tag="RD486_002598"
     CDS             6416..9403
                     /locus_tag="RD486_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDT7664304.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            9552..9761
                     /locus_tag="RD486_002599"
                     /pseudo
     CDS             9552..9761
                     /locus_tag="RD486_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3360 a         1479 c         1879 g         3101 t
ORIGIN      
        1 tcttatcgta gatatatatt ataaatttaa taagaaagcg aggtgagaat cgtgaaaaaa
       61 acgatactaa gtattttttc agtatttaca atattaattg ggggctattt tcttttgaat
      121 ttagattctg ttaattcaaa cgctcaaata aaagatcaaa gagtagctga acataataat
      181 aaaaaaatga gtttgaccaa aaatatctat tctatgtcag atgaagaatt gtataaagaa
      241 tttggtgatt tatccgggga acagttagaa gaaagtattc caggaattag tgactcagat
      301 aaaattgttg tcttgtctgc tggtgggcaa ttaatgggag atggcaaatc cgaattagtt
      361 agttataaac aaaatcacag acagtttatt gatgttaata ctgattccaa cgctatttcg
      421 attaaggatc taaaagagct tttaaatagt aaaagaaatg aattaaagca gataaaagaa
      481 actaattcag tggaattaga gtaaaggaag attcattatg aaaaagattt ttggtgtttc
      541 tgttgggcta cttatgatgt taacatttgg aaatgcagta tatgctgctg agaaagaagt
      601 tatttcagat ccagagcagt acgcctcacg atactttgct gattttgaag aagaagataa
      661 agtacttgca ttgccagaag gtggtttttt aaaaggggaa gctaaaattg tatctatgga
      721 taatccagat ataattcaag gttcatataa ttcagaaact gatcctgctt cagtttcagt
      781 gacagaagca aaaaaaattg ttgctgaaaa attcaaaaat gatattgaaa ctactccaat
      841 tatgcctcga ggagcatttc cacccgatgt tggtactagc ggacaccttc ttgtactagc
      901 aggaggagga agctataaat cacagccatt tagtggtgcg ggatggcgtt ttggaggtat
      961 gggtgtaaaa ccagctgatg gtacaggcaa ctttttacgt tggaaatcct acattgacga
     1021 tggaagagta ggaaatgtaa atcaagccaa cgcaactaaa tctggttcta ttcaaggaat
     1081 ggcattgtat gctcgtgaag gattcaaata ctttgcacca aacgggcctg gttggacaat
     1141 gaatataggt atttattaca cttataatcc tgttgcaggt acgtattatg ttgttcaaaa
     1201 tatttaataa aacagcacaa agagatttct ttgtgctgtt ttattatttt tagttgttga
     1261 caaacactaa aatataaaat ataatcaaca cataaacgaa cgtatgttcg gcaagaaagc
     1321 aggggatttt tatggatgag atggttttaa gtactcagaa atggctaaac aagaaataca
     1381 gtaatgttac agggtttgat aaggttccag aaaatgggcg aacagggtgg cctacaatct
     1441 atggacttat tgaaggacta caagtagaac ttggtattac taatctagta gctaattttg
     1501 gacctaccac tgaaaaaatg tacgataatc aggttactcc taaatggggc aaaaatctac
     1561 ctaaaaatat tgtatttctt attcaaggtg ccttttggtg taaggggatt aatccaggtg
     1621 gcttcgatgg ggtatatact ccatatttag atactgctgt aaaagagttg cagactgatg
     1681 cagggtttaa tggaagcgct gtaactggag ttttggatgc gaaatgggcc aaagcgttat
     1741 ttgatatgag tgcttttgtt cttgttcccg gcggagatag taaaattaga aaaatgcagc
     1801 aatggttaaa tgtaaattat ttagaataca cgggaataat gccttgtgat ggtatttatc
     1861 aaagaaattc aaatcaagca ttaatttttg cattacaagc tgaactagga tattctccca
     1921 gtgaagcaac agggtcttat ggtaatggga caactagtaa aacttatcct gtgtctgaag
     1981 gtaactcggg aaactatgta agaataattc aatatggatt atatgttaat ggttattttg
     2041 aagacggtac attcgatggt attttcacta aatatatggg tttagaagta ctggcattcc
     2101 gaaaatttat ggtattgcct gaatatactg aaatagcaga tgttgttgta ataaaaggac
     2161 tattgtctag cgctggagat attagaagat ctgcagatgg cgcagatact tctacgcaat
     2221 taactagatc tcaaatccaa acattggttg ataatgatat aaaaatagtt ggtagatatc
     2281 ttactggtac tgttggaatt ggaaaagatg aacgaaataa gtatctaact acagaggaat
     2341 tgaataatat tttttctaaa aatttatctg tgtttcctat ctatcaagat ggaggtgcag
     2401 cattagctta ttttacttat gatcgtggct tatcagatgg taagaaggct atagatgcag
     2461 caaaaaatct aaatatacca ttaacaacag ttatttattt tgctgttgat ctagacatgt
     2521 taggggaaga aattcttgca tatgctggag aatattttaa gggggtatct gctgtaatgt
     2581 catatagcgg gtatcaaacg ggtgtttacg gaacaagaaa tgtttgttct caaataatca
     2641 ataacgggta tgcttcgttt gcatttgttt cagatatgtc gactggttat agtgggaatt
     2701 taggttttcc tatgcctaga caatggtctt ttgatcaatt tgttgaattt accataggaa
     2761 gtggcaacgg agctgttggt atcgatttaa tcgctacatc gggtagagat agcggattta
     2821 atgagttatc aaatgatact aataatgata attacattgc caaatacaat cagaaggtta
     2881 taaatcagat ggtacgtgcg tatcaatatc tatcacaagc tggtcttgat aatccttgga
     2941 accctcattt gacattttat agatatgtaa attattctgg tttgtcatgg gacatcattt
     3001 cttctcctgt aacagagcat gatagaaaaa tttatgatga atataggaat aaattaacta
     3061 atagcgaggg cctgtataat tattttatag atcctaatac tggttcaata ataggtttgc
     3121 ctcacttaat tgtgacgtta caatcacaga tgtttctagc cgacacaatc aatgatagtg
     3181 tttctgactt tgcaggttgg ttaggagatt taatgacttg ctggggtgaa gttaagaaat
     3241 taggaataca aatggagcaa ggtgtatttg cattagtagg tacggctgca ggtggaacat
     3301 ttagtctaga agatttatac caagatgttg acgcggtaaa tgtttatacc ttagcaaaaa
     3361 gaaattctga ttcaacagct ttatcggctt taaaaacgta ctattgtgat aagggtgcta
     3421 ttgatagatt taatcaattt gttaagaaca gatttggttc ttcagataaa atcgcttcag
     3481 taacaaatag tttattagaa aatgacgaaa cagttgatat cttaggtgta gggataattt
     3541 catttttcat tgataaaata gttaataatt cacttgggac agattttact tatcttgatt
     3601 ttattggaga tgaggggaaa gttgcaaatg gattttctga aaaaattatt caatttcaag
     3661 aaaatagaag taaacttaat taagaatcgt ttactattta aacagtgtcc ttttcctttt
     3721 taaatatata cgataaaata agtatatgaa ttgtaaaagg acatgatgat tatggaagaa
     3781 atagaatgga ataatctgac tcaaaataat aaaaataatt ctggatgtgg aattatcttt
     3841 atgtttgtta tagttttggg aatagtagta cttttaataa ctgtcaagat agtagattac
     3901 tttgcgaata ctcctgaaga acaaatacag agaaaacttc ctgagtttga aagagtacca
     3961 ccttatgatc caagagataa ttcatttcaa gtaaaaaaat taaaagagtc tccaaatgaa
     4021 atgtggtttg aagttacagt tgaatcaagc gacttcaaag aaaaaaagaa agaatacaat
     4081 tatattgtaa aggcaaaagt atcaaaaaga tttattttta accctaaatt agaaatatat
     4141 agtgttgtaa tagaataata gtgttaaaaa aattgtaaaa gttaaagaag tcaaattctg
     4201 atgtgaaaaa taaaatatac catggaagac ataaaagaaa aactggataa ctagtttatt
     4261 taatggcaga ccgttaaggc ctgccatttt tatgtatttt agcggaataa atataatcat
     4321 gcgggagtgt aaacttactg tttcaaaaag tatacttttt gacatgcctt gattttcttt
     4381 gtttatgtat ggcataataa ccacataata caatttgaaa cgtttctgat ttaatctgat
     4441 tgttttgaaa caattttagt gaaaaaaggg tagataaaaa cgatgagaaa atttttttat
     4501 atccgggtca gtagttatga tcaatcgatc gaacgacaac tgatttccgc gaaggaatta
     4561 ggaatccctg aagaatatat atttgtagaa aaagccagcg gcaaagattt taaacgccct
     4621 gaatatcaat taatgaaacg gatgtttcga aaaggagatt tactctatct acaatcatta
     4681 gatagactag gcagaaataa acaaatgatt ttagaagaat ggcgagaatt aactaaggaa
     4741 aagcagattg atatttctgt gttagacatg cctctgttag atactgctag ttacaagcaa
     4801 ctagatgggt tagagacgct tatctctgac ttaattctgc aattactcag ctatatggcc
     4861 gaagacgagc ggaaacgaat taatagccgg caaagagaag gcgtagaagc tgcgaaacaa
     4921 aagggtgtaa aattcggcag aaagaaaatt gctttacctc ctgaatttcc tgcgatctat
     4981 tctgactgga aagcaggaaa gataactgca gtctatgcta tggatcaatt gggcatgaaa
     5041 cgaaatacct tttatcgacg ggtgaaagaa tatgaacata ccttgcacca cttttcttga
     5101 tagatataac agctattaga cgggaaggga gagtttgaaa atggacttaa cgaatcaaag
     5161 ggtcgttttt actggaacgc tgcagcaaat gacacgaacc caagccatcg gtttggttca
     5221 ctctttaaac ggccattgtc aatcaagtgt tacttcaaaa acaaatttcc tggtttgtgg
     5281 tcagtattct aagtcgttgt ttgatgattc tctctataca aaaaaggaac aaaccgcgcg
     5341 ggacttgatt gcgttaggtc atgagattac cattttatca gaagtcgaat tttatgcgtt
     5401 aattagtcaa cagttgaaag aatggcaacg gtatttataa tcgttagtaa aatttacaag
     5461 gaggaaaatt tttatgaagc gaaaatctta tgatcgttgg ggcattgaaa taactagttt
     5521 taatcgaaat attgcttttc acgtggagtg tgactgtggg gaattagcaa aaagtgttta
     5581 tcaaaaaaat tacttttact gtcctaaatg ccatcgccga tacggggtac atggaacata
     5641 gaaacgaaat agtgcggtag aaaagcgaat gaatgtagta tatttctaca aatcattcgc
     5701 tttctttatt ttataaatag ttggtcgaga gatcccgttt tcttttgcaa tctctgcaac
     5761 tggaatgcct tgctttaaca tgtccaccac ggttttaaaa actaagcgtt tttgcggatc
     5821 tgttgagtta atagaatact cgattggtcg tcccttatat cggccggctt tttgagccaa
     5881 taatactcct tgccgctgac gttcacgaat tttctcacgc tcgttttgtg caatataact
     5941 tagcagtgat aaaaacatat cgaacatagc ggtatccagg agttcatttc cagtattaaa
     6001 atctaaaaac tgtgcatcta atatttttaa cgctactttt ttctgtttca taaaagcaac
     6061 tgtatttttt atatcttcat aatctcttcc taaacgatct agtgatgtaa cgatgacgca
     6121 atcaccttca cggatataat ttagtaattt ttgaaactca ggacgctcag tatctttacc
     6181 actggctttt tcttggaata atttatcaat gttaagtcct tccatcattg ccaattgtcg
     6241 atccaaattt tgatcttgtg aagatactcg aatatagcca atttttccca taaaaaactc
     6301 ctttttaaaa gtgatataat ttacatgtaa aatttacttg tagttttact gctatcatag
     6361 catttttaaa aataaatttt atgtagactt aaaatttact tcatggaggg tttaaatgga
     6421 tgaaatcaaa agtaacaaaa aagcatttgg catttattta ggagaaccta gtacagaaca
     6481 attaaaccaa tttttttatt tgcatgaaaa agatttagaa ttgatggaga ctatacgacg
     6541 accagctact agattaggtt ttgcactaca gttagtctca ctacgttttt taggaacttt
     6601 tatattagat cttaccaata ttccccaaaa tgtattgagt tatgtagcaa ctcaactaaa
     6661 tattgatcct ggagaaatta tctactatag caggagacag accaggtatc agcacacaaa
     6721 attgataaaa tcacattatg gatatcaaga tttcaaccaa ccggaaatag aaacatacct
     6781 agctaactgg cttttaaata gagcgctgta tacaacagaa tcttcagata tgttgtttga
     6841 tatgcttcta aaaaaatgtc tggatgaaaa gattgtttta cctggaatta ctactttttc
     6901 tcgttttgtt gctagtgcaa ttgaaaaagc tgaagagcat ttataccgac aattgtcttt
     6961 ggttccaact gaagatgaga gaaagcggct tctcaatcat ttagaattaa ttggaactcc
     7021 agtttatggg gcaataatca aaatggacat tttgagaacc ccgttagctg acgatagtca
     7081 taaagaaata gccagaggtt ttgaccgact aaagcaattt caagctttct ctactgaaaa
     7141 atggaagatg gaatctattc ctgaagggaa aataaaagtt cttgcaaatt atgcatttaa
     7201 agctaaagct caattaattc aacgaatgag tgaacagaaa aaactggcgt tgttagtggc
     7261 atttattttc atatacaaac gtaaggctat ggatgaacaa attttagcac tatctaattt
     7321 ttttgaaact gtttttagac gcgccaaaaa taaggaatct aaagaacgtc ttcgtaccat
     7381 aaaagatcta gatcgagccg catcgacact ttcagatatt gtagatttag taatgtccag
     7441 tcattctgat actaatgaac tatcccttcg cgatcgtatc ttagaaaaat attctgagga
     7501 aaatgttacc gaagctgtat cgcaagttcg gctattggtt aaaaatgatc gtgaaccaat
     7561 agccatttct gaacttctga acacttatcg aaagttcaga aaatttattc cggatatttt
     7621 aactacacta acatttgaca gcaatgacta cggtaacaac tgtaaggaac tctggacctt
     7681 cattaataat agatttccta agccgattac ttacaaaatg tttggagcta ttaaacatac
     7741 tcttccaaag aaatggattt attacattca tgaataccct gaacaaacta ataaatgtgt
     7801 attgattgca gctgtcgaat tgttaattca atctttaaaa cgccatgata tttatattcc
     7861 tcagagtgtc ttatataaca atcctatgga ttgcttgatt gatgagaaaa cttgggttca
     7921 acaaaaatac gttttattag aacaactaga tcttccttct tcagcaaatg aaatgtcttt
     7981 atggttaaag aacgatttgg aactgtctta taaagaagcg ctaaatcgtt ggcctacttc
     8041 taaaatggcc agaatagaaa atgcagatcg cctggttgtc tctagactta aaaagacata
     8101 tgaaaaaaag gaagataagt cttttagacg tcgcattcag cagttacttc ctaaaattga
     8161 tttgtcagat ttgttattgg aagtaaacca acagttaaat cttactcaat catttaacca
     8221 cttaagtgac aaggacacca aaatgaaaga cttggatatt agtttattag cagttctttt
     8281 atcagagtcc tgcaatattg gtttttcccc ggtttcaaaa gaaggatttg attctttaaa
     8341 gtatgatcgt cttgtctatg tcaatcatca ttatattcga gtggatacac tttcaggagc
     8401 taatcaaaaa ataatacatg cacacaggaa acttgccacc tctaagatat ggggtgatgg
     8461 gcatatggct tcagctgacg gtattcgtta tatcacacca caacgttccc tatattctag
     8521 aagtaatcca aaatattttg gccgtggtcg tgggatcaca ttctacaatt ttgtctctga
     8581 tcaatatata gggttccacg gaatggtcgt ttcagggaca ctgcgagatt cgctttacct
     8641 tctagaagga ttcctcaatc aacccagcga attaactcct aatcagatca tgactgatac
     8701 agctggttat agcgatatga tttttggtct ctttggctta ttagggtttc aatttagtcc
     8761 aagaattgcc aatgataaag gaaccaaact ttggcgaatc gacgctaacg ctcactacgg
     8821 ggaacttgat acgttgtctc aaaattcaat taatatggaa ctgatttata cccattggga
     8881 ggacattctt agggttgcag gttcgttgaa atctggaaaa gtgaatgcaa cagaattaac
     8941 gaaatctctt caacggaatg ggcaacccac gcctttagga aaagcaataa ctgagtatgg
     9001 aaaagtttat aagacgaaac atcagcttcg ttatatttct gacgaaatat atgcacggca
     9061 aattttagaa caattgaata agggggaagc tcggcatgcc ttatgccgta atatttttta
     9121 tggacgaaaa ggaaaactct accagactta ttatgatggg atggaagagc agctcaatgc
     9181 attaggatta gttactaatg ccatcatata ttggaactca ctgtatttag aaaaagtatt
     9241 tgaacaaatg aaagctgaag gattcgactg ttccgaagaa atgatacgca ggcaatctcc
     9301 actaattagt gatcacatca attttgttgg taagtatacg tttagatacg aagctgaatt
     9361 atccaacggt aagttacgtc cattgaatgt agaagaattc tagcaatgtt cgggttttgc
     9421 atgctaccgc actatttcgt atgactgttc cagcgaatca cttcgaatag aaaaagagaa
     9481 aaacacgaga acagcgttaa atcaacgttt cttgtgtttt tacttttgtg ctaccgcact
     9541 atttcgtttc tatgttccat gtaccccttt atcaagaagc gcaaacacgc caaattgccg
     9601 attggttgat cggcatgaac gcaagccctt tatatacctt gaatttacaa caaaaaggcg
     9661 tacaaggtac attttcatta ggacgtgtac aaacaccgac tttatatctc atttatcaac
     9721 gccaggaagc aatagaaaac tttaaaaaag aacctttttt cctgaataat tcatagtttt
     9781 actaatagtc tttcctaaca ttgatttaat agtctttaa
//
LOCUS       DAPBBV010000073         9336 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.075, whole genome shotgun sequence.
ACCESSION   DAPBBV010000073 DAPBBV010000000
VERSION     DAPBBV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.075"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..280)
                     /locus_tag="RD486_002600"
     CDS             complement(<1..280)
                     /locus_tag="RD486_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7664305.1"
                     /translation="MSITKNIKCTDEKTSHSIKQILNIKDSHITFSKDAISKERVHGR
                     MANVFTGLLTGEAHRCECCGFDSVIRHAYHDSWIQLLPYQEVPTYLHLY"
     gene            complement(428..986)
                     /locus_tag="RD486_002601"
                     /pseudo
     CDS             complement(428..986)
                     /locus_tag="RD486_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302360.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1155..3266
                     /locus_tag="RD486_002602"
     CDS             1155..3266
                     /locus_tag="RD486_002602"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012579.1,HMM:NF013070.1,HMM:NF019826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7664306.1"
                     /translation="MNTKDLKLLETIVRSHVTNSQQLKSLVHFSTRQITYSIKKINDE
                     LSLHGLSLIKRSNSGEWLYEANDLQKLLIYMNQAMVFKEGAIPEYINDDLAYSEIRRY
                     SELLFILANPKKVTTQEIMAFIGISKNTARNDFSKIKKELPPDYTLIFDPQNGYMIES
                     SMAKLHTLLLEVFNYLFERHATVNRFESLFSEEREFVGFFIHTYEQTFKLKFSDNSLT
                     KLYYLIGLSLSSFKRRTKGQIDFSYDLQELDEFQMIRSCIDQHYQHAEIAIDYEWLTL
                     LFLSFNTISNEFEILDSRIYQVIMEMITLFQSKSAIRISNKEELTNRLMNHLRPAIYR
                     IRYELPFEIDDLAEIVKENHEVSAVLNFVKESIVPLEAFLRKTIPETELYLISVYFCS
                     ELLNSSIIETPVRKKAIVVCSNGLIMANVMAKTLKEIFPDIQFVASSSVREMDKFVED
                     VDLIFSNQPLKSEIPLYIIQPIMNEEEKNRLRNRVLIDFSTNNISKETRNLTEIIKRY
                     SAVQNEESLQTDIERFLINYANSLIYLDRQSKQAQKISFVELLVSEGIILVSTKQLTW
                     QNAMELSCQPLLKEQVINQNYQTILMSQMADEEAYYFLNNRIAIPHSSPENGVIKGGC
                     SLLISVDPIIFPGNRPIHFISPFAIGKKENYLLAINQLLQLSKDEEYQQEILLCTTED
                     EVRKKIKNFLRRKQYVNNEFS"
     gene            3244..3894
                     /locus_tag="RD486_002603"
     CDS             3244..3894
                     /locus_tag="RD486_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDT7664307.1"
                     /translation="MSITNFPELTIILRGYSFEEAMFVMEELAAMNTSVGIEVTTNND
                     DFARIITEGNKKFGQQLLIGAGTVLTFSQADQAIAGGAKFLLGPKKFSTPIFSLAKER
                     GVVTVPSAFTPSEIQVMFDEGADIVKVFPAVTVGPTYFKQLAGPFGIRPLMAVGGVTI
                     DNIAAFKKAGVVYFGVGSSMFQKADIQNRNGQAIRKSIQSYLDKLAEAGSEEDESH"
     gene            3881..4333
                     /locus_tag="RD486_002604"
     CDS             3881..4333
                     /locus_tag="RD486_002604"
                     /inference="COORDINATES: protein motif:HMM:NF012579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7664308.1"
                     /translation="MSLIKLEEKNILLNQSFSNQEEYFQKITKKLMTENMVKEGYLES
                     ITKRETTYPTGLYIGERSIAIPHTDYQLSNVTAILVSVLKDSLHFQRMDDPEEMVSVN
                     VIIHLLFDSPDKQPQLLKELMSKVTNQDFLQAIMEAKSKTEVLTAFNQ"
     gene            4350..4655
                     /locus_tag="RD486_002605"
     CDS             4350..4655
                     /locus_tag="RD486_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIB"
                     /protein_id="HDT7664309.1"
                     /translation="MSKKTIIVACASSMITSTMAANKIRKIAKTNGLPEPRILQLKFS
                     EVAGALESNQVDFIVPTGKLQENVTKGIKVIPGTPFVTGVNEEKSESLVLEALKELD"
     gene            4667..5944
                     /locus_tag="RD486_002606"
     CDS             4667..5944
                     /locus_tag="RD486_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010492829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IIABC"
                     /protein_id="HDT7664310.1"
                     /translation="MNIVIDALNWISSLGPMIMMPIIILILGLFFRIKLNTLLKSALT
                     VGIGFAGVNIIINWFISQVGPSVQLMVKNWGIQTSIMDVGWPARAAATWSFPLAAVMV
                     FIILGINVLMLIFKKTNTVMVDFWSYNHYIFVAALVYYATDKNIILAVIFGAIDAIIS
                     FKLADWTTPLVEDYFELEGVNFPTANSVGWAPLAWLLNKLWDRIPGLNKVDARPEKIQ
                     ERFGFVGEPMFMGFVIGLVIGLLAKEPVDKVLIVGMSTSATMVLTPKMMQILMEGLLP
                     FANSVKKFLNVKFPGNNFTMGVDAALTVANSSAIATGIIMVPITLVLAAILPGNKLLP
                     ISDIAYQAMWLSAWPVAFSKGNIIRGILSTTIITACVLLIATSLAGIHTQLALAGGFQ
                     LPAGMTQISTEDAGTHIIGFILMKIAEFISNIF"
     gene            5963..7111
                     /gene="dgoD"
                     /locus_tag="RD486_002607"
     CDS             5963..7111
                     /gene="dgoD"
                     /locus_tag="RD486_002607"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HDT7664311.1"
                     /translation="MKISKITVYKVKPRWIFVKISTDEGIEGWGEMISGTKTETVVAG
                     AYEIGNRFLVGQNPFAIERLFQEMHRSFFRGGPINGTIVSGLEMALWDIKGKALNVPV
                     YELLGGAARDKIKVYSWIGGDRPSEVVEQAQDRVDRGFTAVKMNATEELHYIDSYEKV
                     AEVVERVASIRERFGDTLSIGVDFHGRVHKPMAKVLAKALEPYHPMFLEEVVLPENEE
                     HFSEVANAVAVPLATGERLYTRWQFKSILQQGAIDIIQPDVALCGGILETRKIAAMAE
                     AYDIAVAPHAPYGPIALAATLQVDSCTPNVFIQEQSLGIHYNKGFDLLDFVKNKEIFQ
                     YKDGFVDLPTKPGLGLEMDEDRVKEIAQEGLVWTNPKWKNYDGTIAEW"
     gene            7123..8025
                     /locus_tag="RD486_002608"
     CDS             7123..8025
                     /locus_tag="RD486_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryldialkylphosphatase"
                     /protein_id="HDT7664312.1"
                     /translation="MINTVTGPIEAESLGTTFIHEHLYVIPNELRKYEDYTLDDIYHS
                     IAEVMAFKQAGGKTIVDLTPINYGRNPLALKMISEATGVNVAFVTGFHKEEFQPKWLT
                     TLNDDEIFELLYSEITHGVTSQNLLPGAMKVGTSKNEVTLAEQRILAIAGQVQKKTGI
                     PIITHCDGGTMGLEQINCLTKNGAKASNICLSHVDLTKDFHYLAQICETGASICMDHI
                     GRELANHDADRVQLIKRLVDAGYENQICLSGDMGRKKYLPTYGGTPGLTYILTSLKEE
                     LLKVMSEPTFNKMIEMNPINILSK"
     gene            complement(8694..9080)
                     /locus_tag="RD486_002609"
                     /pseudo
     CDS             complement(8694..9080)
                     /locus_tag="RD486_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252556.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9140..>9336)
                     /locus_tag="RD486_002610"
     CDS             complement(9140..>9336)
                     /locus_tag="RD486_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7664313.1"
                     /translation="NNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRN
                     GTLFGFSVSTEIKVLMGITA"
BASE COUNT         3012 a         1447 c         1904 g         2973 t
ORIGIN      
        1 tgtacaggtg tagataagtt ggtacttctt gatacggaag caactgaatc caactatcat
       61 gataagcatg acggatgaca gaatcaaacc cacaacattc gcaacgatgc gcttctccag
      121 ttaataagcc ggtaaataca ttggccatac ggccatgaac gcgctcttta ctaatggcat
      181 cttttgaaaa ggtaatatgg gaatctttga tgttcaaaat ttgtttgatg gaatgacttg
      241 tcttttcatc cgtacatttg atattcttag ttatggacat ttggttatcc tcctatgatt
      301 gtttttgccg atttaattat aggacaacca gatgtctttt tgttataaaa aaatatttgg
      361 cgtcactact cagtttgagt aacaaaacca aatattatag aaccggcttt ttcagttttt
      421 tcccttcaca aacaacatcg atgattttct cggcatgggt acgggtatca ttcattaatt
      481 ctgtatcggt tggatatttg atgttttgtg gagcacaagt ggcatccaaa atcaatgttc
      541 cggaattgaa atcgtcataa gaatcgttgt ccttatcgtc ttttttcttg tcgaagacga
      601 gtattttttc attgatttct atcaacgttg tttcgtccaa gcgtttccgg aaatagacca
      661 ttgtagagca tcgaaaggct tggcatcttg atagcccggc aaaccgatga agaactataa
      721 atacgggttt tcttgaattt gtaagaccgt ttcttcgtcg ctatagctat attccttttg
      781 aatcagtaga gctccgaagg tcatgcgaaa gggttttgcg acgtttcctt ttttttacga
      841 aaatttttag cgtagtcttt ttcaagttca gcccatggaa tgagctctgc tttttgaatc
      901 caacggttag acggattcat tttgagacct atcggttgat tgaaatcttc aaaagccaat
      961 tgaacggttg tttgtaattt atacatgaaa agcctccaaa attgagtggt actccacacc
     1021 attctgatgg tgcataagat aaaaaattaa agaagtgcct gtcatttgtc tgatttaagc
     1081 caaggtttga caaattttgg atattccaat taatactgta agcggttata tttaactcag
     1141 ggaggtagat gaatgtgaat acaaaagatt taaaactgtt agaaaccatt gtacgatcac
     1201 atgtgacaaa ctctcaacaa ttgaaatcat tagtacattt ttcgactagg cagataactt
     1261 actctataaa aaaaattaat gatgaattat cccttcatgg attgagtctg ataaagcgaa
     1321 gtaactcagg ggagtggtta tatgaagcca atgatcttca aaaacttttg atatacatga
     1381 atcaagcaat ggtttttaaa gaaggtgcga ttcctgaata tataaacgat gatttggctt
     1441 atagtgagat aagaagatat tcggaactgt tatttattct agccaacccc aaaaaagtga
     1501 caacccaaga aataatggcg tttattggta tcagtaaaaa tacggctaga aacgactttt
     1561 ctaaaataaa aaaagagttg ccaccagact acactttgat atttgatccc caaaatggct
     1621 atatgattga atcaagcatg gcaaagcttc atacattgct cttagaagtt ttcaattatt
     1681 tatttgaaag gcatgcaaca gttaaccgtt ttgagtcact cttttctgaa gaaagggaat
     1741 ttgttggttt ttttattcac acctacgaac aaacttttaa attgaaattt tctgataatt
     1801 cactaaccaa actttattat ttgataggtt tatcactttc tagttttaaa agaaggacga
     1861 aaggacagat tgattttagt tatgatttac aggaattaga tgagtttcaa atgattcgaa
     1921 gctgcattga tcaacattat caacatgctg agatagctat agattatgaa tggttgacgc
     1981 ttctgttttt atcattcaat acaatttcaa atgagtttga aattttagat tcaagaatct
     2041 atcaagtaat tatggagatg attaccttat ttcaaagtaa atcagctatt cggattagta
     2101 ataaagaaga gttgaccaat cgattgatga atcatttacg acctgcaatc tatcgaattc
     2161 gctacgaatt accatttgaa atagatgatt tagctgaaat tgttaaggaa aaccatgaag
     2221 ttagtgcggt acttaatttt gttaaagaat ccattgtacc tttggaagca tttttgcgta
     2281 agacgattcc tgaaactgaa ttatatttga tttctgttta tttttgttcg gagctattaa
     2341 attcttctat tatcgaaaca cctgttagaa aaaaggcaat cgtcgtatgt agcaatggat
     2401 tgattatggc caatgtaatg gcgaaaacat tgaaagaaat ttttccagat attcagtttg
     2461 ttgctagttc ttcggtcaga gagatggata agtttgtcga agatgttgat ttgattttta
     2521 gcaatcaacc attgaaaagt gaaattccat tatatattat acaaccgatt atgaacgaag
     2581 aagaaaaaaa ccgcttgcgg aaccgtgtac tcattgattt ttctacgaat aatatcagca
     2641 aagagactag gaaccttact gaaattatta agcgttactc tgctgttcaa aatgaagaaa
     2701 gtctacaaac tgatattgag agatttttaa ttaattatgc aaattcacta atatatctag
     2761 atcgtcaaag taaacaggca caaaagatat cttttgtgga attgcttgtt tctgaaggga
     2821 ttattcttgt atctacgaaa caacttactt ggcagaacgc gatggaattg tcttgtcagc
     2881 ctttattaaa ggagcaggta attaatcaga actatcagac tattttaatg agtcaaatgg
     2941 cggatgaaga ggcttattat tttcttaata atcgtattgc tattccacat tcatcgccag
     3001 aaaatggggt aattaagggc ggttgctcgt tacttatatc agttgatcca attatttttc
     3061 ctggaaatag gcctatccat tttatttccc cttttgcaat tggaaagaag gaaaattatt
     3121 tacttgcgat taaccaatta ctacaacttt ctaaggacga ggaatatcag caagaaatac
     3181 ttctttgcac gacggaagat gaagtgagaa aaaaaataaa aaatttttta aggaggaagc
     3241 aatatgtcaa taacgaattt tcctgaatta accatcattt taagaggata tagttttgaa
     3301 gaggcgatgt ttgtcatgga agaattggct gcgatgaaca cttcggtagg aattgaagta
     3361 acaaccaata atgatgactt tgcacgtatc atcacagaag gcaacaaaaa atttgggcaa
     3421 caattattga ttggtgcagg gacagtttta acattttcac aagcagatca agcaattgct
     3481 ggtggtgcga aatttttatt aggaccaaaa aaattttcaa caccaatttt ttcgttggct
     3541 aaagaacgtg gggtggtaac tgtgccatca gcttttacgc catcggaaat tcaagttatg
     3601 tttgatgaag gtgccgatat tgtaaaggtt tttccagcag tcactgtagg gccaacctac
     3661 tttaaacaac tggccggtcc ttttggtata cggcctttaa tggcagttgg aggagtgacg
     3721 attgataata ttgcggcttt taaaaaagca ggagttgtgt actttggggt aggatcaagc
     3781 atgtttcaaa aagctgatat acaaaaccgc aatgggcaag ctattcgaaa atcaattcaa
     3841 tcatatttag ataaactagc tgaagcagga agtgaagaag atgagtctca ttaaattaga
     3901 agaaaaaaat attttgttaa atcaaagttt ttcaaaccaa gaagaatact ttcaaaagat
     3961 tacaaagaaa ctgatgacgg aaaacatggt aaaggaggga tatctcgagt caatcactaa
     4021 gagagaaaca acttatccaa cggggctata tattggggaa cgctcaatcg caattccaca
     4081 tacagattat cagttatcaa atgttaccgc tattttagta tccgttctta aagatagttt
     4141 gcattttcag cgaatggatg atcccgaaga aatggtttca gtgaatgtta ttattcacct
     4201 tttattcgat agtcccgata agcaaccgca attattgaag gagttgatga gtaaagttac
     4261 caatcaggat ttcttacaag caattatgga agcaaagagt aaaacagaag ttttaactgc
     4321 atttaatcaa taaattggag ggaaatacaa tgagtaaaaa aacaattatc gtcgcatgtg
     4381 catcatcaat gattacatct acaatggcag ctaataaaat tcggaaaata gcaaaaacaa
     4441 atggattacc agaacctcga attttgcaac taaaattttc agaagttgca ggtgctttag
     4501 aatcaaatca agttgacttt atcgttccta cagggaaatt acaagaaaat gtaaccaaag
     4561 gaattaaagt tatacctgga acaccatttg ttactggagt gaatgaagaa aaatctgaat
     4621 ctttggtgtt agaagcattg aaagagcttg actaggaggg tgaaaaatga atattgtcat
     4681 tgatgcgtta aactggatct caagtttggg tccgatgatt atgatgccta tcattatctt
     4741 gattttagga ttatttttta gaattaagct aaatacatta ctaaaatcag cgttgactgt
     4801 ggggattggt tttgcgggtg taaatattat tattaattgg tttatttcac aggtaggtcc
     4861 atctgttcag ttaatggtca aaaattgggg tattcaaaca agtattatgg atgtcggctg
     4921 gccagctcgt gcagcagcca cttggtcttt tcctctagca gcagttatgg tatttattat
     4981 tttgggtatt aatgtgttga tgctgatttt taaaaagacc aatacagtaa tggtcgattt
     5041 ctggagttat aatcactata tttttgtagc tgctttggtt tattatgcaa cggataaaaa
     5101 tattatattg gcggtaatct tcggggcgat tgatgcaatt attagtttta aactcgctga
     5161 ttggacaacg ccgttagtag aggattactt tgaactagaa ggggttaatt tcccgactgc
     5221 gaactcagtt ggttgggcac ccttggcttg gctacttaac aaattgtggg accgcattcc
     5281 tggattaaat aaggtagatg ctcgtcctga aaaaattcaa gagcggtttg gttttgttgg
     5341 tgagcctatg tttatgggat ttgtcatcgg cttggttatt gggttattag caaaagaacc
     5401 tgttgataag gtattgatag tgggaatgag tacttctgca acaatggttc taacacctaa
     5461 aatgatgcaa attttaatgg aaggattatt accctttgct aattctgtta agaaattctt
     5521 gaatgtaaaa tttccaggaa acaattttac aatgggtgtg gatgctgcgt tgacagttgc
     5581 taattcaagt gccattgcta cgggtattat catggttccg attaccttag tgttggctgc
     5641 tattttacca ggtaacaaac tcttacctat ttcagatatt gcctaccaag caatgtggct
     5701 atctgcatgg ccggtcgcct tttcaaaagg aaatattatt cgcggaatac tttccaccac
     5761 gattataaca gcttgtgtgc ttttaattgc tactagttta gccggcatac atacacaatt
     5821 agctttggct gggggattcc aattaccagc aggaatgaca caaatatcta ccgaagatgc
     5881 aggtacacac attattggtt tcattttaat gaagattgct gagtttattt caaatatttt
     5941 ctaatattca ggagggcata cagtgaaaat ttcaaaaatt acagtctata aagtaaaacc
     6001 aagatggatt tttgtcaaaa tatctacaga tgaaggtatt gaaggctggg gtgaaatgat
     6061 ttctggaact aagactgaaa cagttgtggc aggagcttat gagataggaa atcgattctt
     6121 agttggtcaa aacccatttg caattgaacg tctgtttcag gaaatgcatc gttcattttt
     6181 ccgaggtggt cctattaatg gaacgattgt ctctggactt gaaatggctt tatgggatat
     6241 taaagggaaa gccttaaatg ttccagttta tgaattacta ggtggagcag cccgtgataa
     6301 aatcaaagta tattcttgga ttggtggaga tcgtccttct gaagtagtag agcaggcaca
     6361 agatcgagta gatcgtgggt ttaccgccgt gaaaatgaac gcgacagaag aattacacta
     6421 cattgattct tatgaaaaag tagctgaagt agtggaacgt gttgcttcaa ttagagaacg
     6481 ttttggagat acattgagca ttggtgtcga ttttcatggt cgtgttcaca aaccaatggc
     6541 taaggtttta gcaaaagcac tggaacccta tcatccaatg ttcttagaag aagtggtttt
     6601 gccggagaat gaagaacatt tcagtgaagt agccaatgca gttgctgtac cactagcaac
     6661 gggtgaacgt ttgtatacaa gatggcaatt taaatcaatt cttcaacagg gagcgattga
     6721 tatcattcaa ccagatgtag ctttatgtgg agggatttta gaaacaagaa aaattgctgc
     6781 aatggctgaa gcttatgata tagcagttgc cccccatgca ccatatggac cgattgcgtt
     6841 agcagctaca ttacaagttg attcttgtac acctaatgtg tttattcaag aacaaagctt
     6901 aggtattcat tacaacaaag ggtttgattt gttagatttt gtaaagaata aagagatatt
     6961 ccaatacaaa gatggcttcg tagatcttcc gacaaaacca ggtttagggt tagaaatgga
     7021 cgaagatcga gtgaaagaaa ttgcacaaga aggtttagtt tggaccaatc ctaagtggaa
     7081 aaattatgat ggtacaatcg ctgaatggta ggagatgagt gcatgatcaa tacggttaca
     7141 ggcccaatcg aagctgagtc tttgggtaca acatttattc atgaacattt atatgtcatt
     7201 cctaatgagt taagaaagta tgaagattat accttggatg atatttatca tagtattgcg
     7261 gaagttatgg cttttaaaca agctggtgga aaaactatcg ttgatttgac accaattaat
     7321 tatggacgaa atccgttagc tttgaaaatg atatctgaag ctaccggagt gaatgtagca
     7381 tttgttacgg gattccataa ggaagagttt cagccaaaat ggttgacaac gctcaatgat
     7441 gatgagatct ttgagttgct ttattccgaa ataactcacg gagtcacttc acaaaacctt
     7501 ttgccaggag caatgaaagt aggtacgagt aaaaatgagg ttacattggc tgaacaacga
     7561 atactagcca tagccggtca agtacaaaaa aaaacaggga ttcccattat tacgcattgt
     7621 gatgggggga cgatgggact ggagcaaatt aattgtttaa caaaaaacgg tgcgaaagca
     7681 agtaatattt gtttgagtca tgtagattta actaaagatt ttcactattt agctcaaatc
     7741 tgtgaaacgg gagcaagtat ttgtatggat catattggcc gagagttggc gaatcatgat
     7801 gcagaccgcg tccaactaat taaacgactg gttgatgcgg gttatgaaaa tcagatttgt
     7861 ctttcaggtg atatgggacg aaaaaaatat ttgccaactt atggaggaac gcctgggctt
     7921 acctatattt taacaagttt gaaagaagaa ctattaaaag taatgagtga accaactttt
     7981 aataaaatga ttgagatgaa tccaattaat atactgagta agtgaagtca attgaatcat
     8041 tcagaagaac taatgaaatt agttgctttc gcagggttaa ttcttctctc tgggtttgga
     8101 aaagagggct tagcttcgga ttccctagtt aaactagggg ttttatcagg ttattgtact
     8161 gattataagt acctgaatta ttcatgaaat actttttccg tcgttttata ggcagttggg
     8221 tcaataaaaa gatcagaaaa acgaacgaga gactctcata acgtgccact aaataaaaat
     8281 cgtacgttat tttaaaaaat gggttgattc taggcagtac tttgtcggtc tatttttaga
     8341 aaaagaggtt ctttgtcaaa catacatgaa ttcgcaagct cattcaccct gaaggatgaa
     8401 aggcagaaac tgtagtatac taatggtgga aaggaaaaaa agccgccagc aatttggaaa
     8461 agaacgttat gtcgattgtc aaactggctt gctttatttc tcgagaaccc tgaaatatag
     8521 ccaatgagca tgtgtataaa aaattgattt tatatgaaat aaagcactcc tttcctaaaa
     8581 ttattggaaa ggagtgcgtt ttttatggaa attatttagg ttctttgtca attgctattg
     8641 ttttgctcaa atcgtatgtt aggaaatgct tcggcatttc cttttttgcg ttattaaatg
     8701 atttcacaga tgttctgttg aatcaggaca cgcatccgga gatgacgaaa agtccgaaat
     8761 ccaaaagcaa ttcttttgat tactttgatg aggttattct ttccctccaa ttttccgttt
     8821 gaatagggat attttaagga gtttgtgatt gcttctgtgt gctttttcag ataacaaatt
     8881 gcctttttaa acccatcatt caaggaatgt ggcaatgatt caatgagatt gaaaaattca
     8941 gtaaaatctt ttgcatcaaa agcagctaat aactcttgat agacttcata gctttgtcgt
     9001 agttggttat ctatagagag taggtaatca agcacctccg actccgtcat gtatttccct
     9061 tggaagaggg gaaattgctt aaaagggttc tgttgcgaag tttgaaaatc aaacgcgccc
     9121 tctctgaact ccaaatatct taggctgtta ttcccattaa taccttgatt tcagtagaca
     9181 ccgaaaagcc gaagagcgtt ccatttcttc ggttcttttt atatattcct cgaatggtct
     9241 ccatgccctt aatcgtggaa gaggctgtac ggagactttg ataaaattta tttcgtcgtt
     9301 taataggtcg atggtcttgt tctattaaat tgttaa
//
LOCUS       DAPBBV010000074         9284 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.076, whole genome shotgun sequence.
ACCESSION   DAPBBV010000074 DAPBBV010000000
VERSION     DAPBBV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.076"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            1..270
                     /locus_tag="RD486_002611"
                     /pseudo
     CDS             1..270
                     /locus_tag="RD486_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751573.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
     gene            809..1009
                     /locus_tag="RD486_002612"
                     /pseudo
     CDS             809..1009
                     /locus_tag="RD486_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1496..1675
                     /locus_tag="RD486_002613"
     CDS             1496..1675
                     /locus_tag="RD486_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664314.1"
                     /translation="MTELTADMSDTWLQEYLFPEKQTTARGYLPVDWEYVHKELMKKN
                     MTLKLLHREYGVHGT"
     gene            complement(1721..2326)
                     /locus_tag="RD486_002614"
     CDS             complement(1721..2326)
                     /locus_tag="RD486_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7664315.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2508..2843
                     /locus_tag="RD486_002615"
                     /pseudo
     CDS             2508..2843
                     /locus_tag="RD486_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            3008..3235
                     /locus_tag="RD486_002616"
                     /pseudo
     CDS             3008..3235
                     /locus_tag="RD486_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3361..4332
                     /locus_tag="RD486_002617"
     CDS             3361..4332
                     /locus_tag="RD486_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7664316.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4472..5785
                     /locus_tag="RD486_002618"
     CDS             4472..5785
                     /locus_tag="RD486_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDT7664317.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5828..6694
                     /locus_tag="RD486_002619"
     CDS             5828..6694
                     /locus_tag="RD486_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7664318.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6691..7539
                     /locus_tag="RD486_002620"
     CDS             6691..7539
                     /locus_tag="RD486_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7664319.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7553..9025
                     /locus_tag="RD486_002621"
     CDS             7553..9025
                     /locus_tag="RD486_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HDT7664320.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQKRIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            9042..>9284
                     /locus_tag="RD486_002622"
     CDS             9042..>9284
                     /locus_tag="RD486_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7664321.1"
                     /translation="MIYGSIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         2954 a         1562 c         1895 g         2873 t
ORIGIN      
        1 aaatctatat tttgatatac aaattacagc ttcagatact aagttgcata aaccttttcc
       61 ggaccccata caaaaggcaa ttgatgaatt gggcataaaa aataagaaac gatttatatt
      121 ggtgattcat tatatgacat gcaaagtgcg aaagcttgtg ggatagcatt tggtttagct
      181 aaatggggag ccaaaaatat agaaaatttt caaagtgtag atataattat tgattctcct
      241 caagaaatac ttgatttgtt agaaaaatag acaaagagcg tgagataagg atagggtctc
      301 acgctctttg tttttcgcca tttaaagatt gaaatttttg ccatttaaaa agaaaagtga
      361 cagataggaa taaaaactta ttaaatgtag ttatgatctg ttatatttca tttctaatac
      421 taggtcttcc acaagcagtg tttcctgaaa tgttttctgg agactggggt attgtcagct
      481 attctatatt aacattgatt gctatggttt taggtacttc attttataat gcttttgtaa
      541 gtaagcatgt tgaggaatat gaagtattaa tgtacttaaa agagaaaaaa acaagtaatt
      601 aatatgagaa caccacgcat agtttttatt ttgagatatt ctagaatgaa acacattaag
      661 aacgaaagca aagcaaaaga cgccagaact tctactacct tctaagtttt ttcatatttg
      721 tttgttatgc tatacataga tctgcataat tagacttgcg ctgcccgtta ttgaagtttc
      781 aggcagcgct ctttttgggg gatcgataat ggaagaagaa aaaatatttg agaaacgctg
      841 gcagctagca tcaagtgaac aaagagcaag atacaataat ttgatcacct cctaccccac
      901 tgttgactag acatataagg aaaagaaata cttactttgg ctgtgccagt tagatataga
      961 tacctttgaa acatttgaag tgatcctaga taaaattaaa cagaattgat cagaaacaag
     1021 cgaagccttc tctcggttcg cttgttttgc tatttattag ttggctcagg gcaactctaa
     1081 gctcgtttga aagaaaaccg atggataatc cccttgtttg taccacttta gaatacatgg
     1141 atgtacgtat tgccattgac tcctattagt tactgaaaaa aaatttaaac aagttgagta
     1201 ttgcagataa atagctccag tgaggtgaat aactgctcca ctcaaggcaa tagatagctc
     1261 catccagggc aacaaactgc tccactttca tatttaatag atgaataacc ttctgtataa
     1321 tagaaaggca tacctttcgg tatgacaact tatacagaat gttattttat tggttcacta
     1381 tcgaaaaatt ttggagcttt atttttccgg tatttctcaa cgaacgatta gtttaactgt
     1441 gggaagctcc agacatacga ttcgagaagt tacttctcga gcagacagga agggggtgac
     1501 tgaactaacc gctgatatga gcgatacttg gctgcaggaa tatctttttc cggaaaaaca
     1561 aacaacagca cgaggttacc ttcctgtaga ctgggaatat gttcataaag aactaatgaa
     1621 aaagaatatg acattgaaac tccttcatag agaatatggg gtacatggaa catagaaacg
     1681 aaaatgcacg gtagaaaagc gaatgaatat agtataaatt ctacaaatca ttcgctttct
     1741 ttattttata tatggttggt cgagagagac cattttcttt ggcaatttct gcaactggaa
     1801 ctccttgatt taacatgtcc accacagttt taaagactaa tcgtttttgc ggatctgttg
     1861 agttctcaga atattcaatt ggtcgcccct tatatcgacc agcttttttg gccaataata
     1921 ctccttgccg ctgacgttca cggattttct cacgttcgtt ttgtgcaata taacttagca
     1981 atgataaaaa catatcgaac atagcagtat ctaggagttc atttccagta ttaaaatcta
     2041 aaaactgtgc atctagtatt tttaatgcta cttttttctg tttcataaag gtaactgtat
     2101 tttttatgtc ttcataatct ctgcctaggc gatccagtga tgcaacaatg acacaatcac
     2161 cttctcggat ataatttagt aatttttgaa actcaggtcg ctggatatct ttaccactgg
     2221 ctttttcttg gaataattta tcaatgttaa ggtcttccat cattgccaat tgtcgatcta
     2281 aattttgatc ttgtgaagac actctaatat atccaatttt tgccataaaa actcctttta
     2341 aaaaatgata taatttacat gtaaaattta cttgtagttt tactgttatc atagcatttt
     2401 taaaaataaa ttttaagtct acttataatt tactttggag gttttgaatg aatgaaatta
     2461 agcgcaataa aaattctttt ggtgtttatt taggagagcc tagctcggaa cagttaaata
     2521 aaggtgaagc tcgtcatgct ctatgtcgaa atatatttta tggtagaaaa ggcaaacttt
     2581 atcaaactta ttacgacggt atggaggaac agctcaacgc attaggatta gtaactaatg
     2641 ctatcatata ttggaattca ctatatttag aaaaagtctt tgaacaaatt aaaacggaag
     2701 ggttcgactg ttccgaagaa gtgttacgca agcaatttcc attaattagt gatcacatta
     2761 attttgttgg caaatatagt ttccgctatg aaaaagaatt atcgaatgga atactacgtc
     2821 cgttaaatat agagaattat tgagaatgtt cgtcttttgg ttcctaccgt gcattttcgc
     2881 acggatgttc cagatactat ttttgaatgt ataaaattga aaacacaaga atactaataa
     2941 atcaacgatt cttgtgtttt taatttttca ctaccgtgca ttttcgtttc tatgttccat
     3001 gtaccccaat cttgaaaaat taattaaaga cttagataaa gccattgacg acttagtcgt
     3061 ggtgctaccg gagtatcaat gtttaaccag tatcccaggt attggtcctg tttaggctgc
     3121 tggaatactc gctgaaattg gtccaattga acgtttttct gatgaaataa aattgacaaa
     3181 gtatgccggc ctatattggc gacagagtca atccggtaaa tctgaatacg aaaatttttt
     3241 tacgaaaagc ttcacgtcta atatctattt taaaataaaa atattcctgc taatttggaa
     3301 tcgtttcctt cttttggtat aataatacct gaaattcttt tgagaggagt tgttcgtgaa
     3361 gtgaaaacta ctatgaagga tgttgctgcg ttagcaggag ttggtgtggg tacggtatct
     3421 agagtaataa atggagtaaa ggtgaaagag gttaccaaag aaaaagtaat ggctgcaatt
     3481 agtgagctta attatgagcc tgatgaatat gccagaggta tgaaaacgaa tagtagcaat
     3541 acaatagctc ttattttacc tacgatttgg catcccttct tttccgagtt tgcctactat
     3601 gtagaggaag ctctcagcca aaaaaattat aagctttttt tgtgtaatgc gaacggcagt
     3661 gcggaaaaag aaaaagaata tatccaaatg gtcaagcaga gtaaagtaga cggaattata
     3721 ggtattacct attcagacat tgataaatat gtatcatcaa atttaccatt tgtcagtata
     3781 gaccgccatt tttcggaaca ggtttcttat gtaacggcag ataattattt aggtgggcaa
     3841 attgccgctc aagaactact tactcgtaac tgtaaaaact tgtgctatgt tgggggtgtt
     3901 tcaccttacc ctaacgaaac aaacaatcgt aaagctggtt tttacaatat ttgtgaggaa
     3961 aataaaatag ctgtgaaggt attggatatg cctgaaccaa ttagcaattt agaggaacaa
     4021 ttgctcgctt ttttttcgga taatcctgaa attgatagca tttttaccat caatgatttc
     4081 atggctttgg atgtgataaa agcccaaaaa aaactaggga aggaagcacc taaggatttt
     4141 caaattattg gttttgatgg agtcaagcta tcgttgcaaa aagactattt actatcaacg
     4201 attgtacagc cgatagagga aatggccaag gtttcagtag aaacactcat ggcgatgatt
     4261 ttaaatgaag aaccgcctaa gcgtgtggta gtaccggttt tctttcacgc tggagagacg
     4321 actaaagagt aaaaaaccgg tttataacga tttttttgag ataggttgac agaaagtgat
     4381 ttcaatgata tcttaaaacc aattaattgg aaacgttacc aattaattga aaaataaaac
     4441 ggaaacgttt caaaaaatag gaggaacatc gatgaaaaag agaatgttag caattgcagc
     4501 aattttagca ttaacagctg gaggacttgc aggatgtggc agtaaggaga aaagttcagg
     4561 tagcagtgat ccaggagaaa ttaagatttg ggttcagttt tctgatgaaa cgcctgaagg
     4621 aaaagcttgg gcagagattg tgaacaattt taatgatgaa tacgagggtg aatataaagc
     4681 tgttactgag tatattcctc gtagcggaag cggcggtgga tatgaggata aagtaaatgc
     4741 tgcaattaca accaataccc ttcctgatgt tattacgtta gatggaccga atactgcagc
     4801 ttatgctcat tcaggagtca ttgctccatt agatgattat ttgaaagatg cggacatgga
     4861 tgatgtatta gacagcatta ttcagcaagg aacctacgat ggcaaaatgt atgcgtttgg
     4921 tttctcagag tccagtgtgg gtgtctatta caataagtcg ctgttcaaag atgctggaat
     4981 tacagaagat caattgccga cgttagaaga tccttggact tggacggaat ttcaagcaat
     5041 ttgccaaaag ctgactgata aatacaaaac gcctgcaatt gatatgcaaa tggcgtcggg
     5101 agacgaaatg ctgacctacg catatacacc atttatatgg tcgaatggcg gcgatgtcgt
     5161 taatgctgat ggaaccaaag ccgaagacta ttttaacggt aaaaaatccg ttgaagcgtt
     5221 ggaatttatt caagaattgg ttgaaaaagg ttacaccaca atcagtccta ttgaaaaagg
     5281 atttgaaact ggcaaatatg ccatgatgct gagcggttct tggacaatgg cagatttaga
     5341 ggaaaactat caagagattg attatggtat tttgccttac cccgtttcag atgcaactgg
     5401 ggagttagtt tcaccaaccg gaagctggca gttagcaatg actgagaaaa cagagaaaaa
     5461 ggatgcttct gcggccttta ttaagtttgc aaccagtaca gaatctagtc gtattatgag
     5521 tttagggaac agtgttctac ctatcagaaa ttcaacagtt gatttaatta aagatgaagt
     5581 gtcggaagga atgcaggtat taattaagca aaaccaactt tctggacatg cccgcccagt
     5641 ggttgtagct tatccgcaag tatctagagc attccaacaa gcagttcaag atattagcta
     5701 cttcgaggaa aacccagatg tacaaaaagt agcagatagt cgcgctgctg aaatgcaaca
     5761 ggcaattgat acttcactaa aatagaagtt tctaaagggg gccaatcaag tgttaaaaaa
     5821 accgacaatg aaagacaatt tgataggtta cggctttcta gcgccagctt tgctgctgct
     5881 gacgattttt ctgatcatac ccgtaatcat ggtaatttat tatgccttta ctgattatta
     5941 tttgttaacg ccagatgcta gacaatttat cggcttagaa aattttaagc gactgttcgc
     6001 tgatccaatt tttgtaaaaa gtatttggaa cacggctaaa tttgttgttt ggattattcc
     6061 ggtccaaata ggggcagctt taggaatggc acttattatc aacaaaaatc gtaaaggaaa
     6121 tatctttttt aaagtagcct tttttgcgcc agtcgtgatg tccttagtcg ttatttcgat
     6181 tttatggttg tacttgttaa atcctaatga aggtctggtt aatacgctat ttgcaaagat
     6241 tggaattgct tcgcagcctt ttttgactag tcccaaacaa gcaatgtata cgcttgtttt
     6301 cgtatcggca tggcaaggtg caggatatca gatgctgctg tttttagggg gaatgcaaaa
     6361 tattccgcaa gacgtttatg aggcagccga aattgatggt ttttctaagt ttcagcaatt
     6421 tcgctatatc accatgccat tattaaagcc cacggcgatt tttattttac ttaccacatt
     6481 gatttcggcc tttaaactaa tcattcagcc aatggtaatg actcaaggtg gaccaatgaa
     6541 ttctactatg acaatggttt attacattta ccaaactgga tttacagacc gtatggtagg
     6601 ctactccagc tccattgcgt taatctttac cactatgatt ggtttaatta caattgctca
     6661 aagaaaattg gtaaaggagg atgatccagc atgaccaaga aatttggacc gctaatgatc
     6721 gtagaatatt gtttgctgtt ccttttagcg gcattattca ttttcccgat gctgtggatg
     6781 gtagtttcct ctatgaagcc tgaagcagat gtctatcaaa atttagcttc cttcaaagct
     6841 tttttaccta gtttgaatcc agctaattgg tttaaaactt atcaagaggt tatttcccgg
     6901 ttcagtgtgg gaacttattt attaaacagt attttttatg gtttaacctt tgcctgtggg
     6961 tcaatcattg taaactcttt ggcgggtttt gcctttgcga aggttaattt ttcaggcaag
     7021 aaaattatct ttggagcttt gttagctctg ctgattgtcc cgatggagac ggttttaatt
     7081 ccgcaattta ccatcgttaa ttcactaggc ttagtgaata ctcgcttggc agtgatttta
     7141 ccagcgatgg ccagcgcgtt taatatctat ctgtttagaa atttctttat cgcgattcca
     7201 gaagaaatca ttgaatcagc gaaattagat ggtgcaaata ttgttaaaat tttctttcac
     7261 atcatgctgc caatgtctaa accagccata gccacagtag gtgtcttatc ctttatctcc
     7321 agctggaatg attatatttg gccgttaatg gtcttaactg acagcagcaa attttcaatg
     7381 caagtggcaa ttactacgat caatactaca cagccagttt atatcaatca agtgatggct
     7441 gttttaacca ttgcaacgat tccactgatt attgtttata tcgttgcaca aaaatatatt
     7501 ctgcagggac ttggcggttc tggaacgggt ataaaatagg agtgaatagt gaatgttgca
     7561 aaaactttta aaggccaatg agtttattga gaaaaatgct caaacagtca atcaagaata
     7621 ccggaataaa tttcatttga tggctccgat tggctggatg aatgatccaa atggttttgt
     7681 ttattatcaa gaggagtatc acttgtttta tcaatattat ccttacgaca gcatctgggg
     7741 accaatgcat tggggccatg ctaaaagcaa ggatctaatt cactgggagc atttgccagt
     7801 agcactggca ccaggtgaaa gctatgacaa ggaaggctgt ttttccggca gtgccataga
     7861 aaaggatggc aagctgtatt tgatttatac aggacacaat gttgtggaag ggcaagttcg
     7921 acaagttcag tgtttggcag tttcagaaga tggcattcac tttgaaaaat atgccggaaa
     7981 tccaatcatc gcagaagatc acttagcttc tgttgcaacg accgaagatt tccgcgatcc
     8041 caaagtgttt cagcgaaaag aagactattt tactgtagtc gctactaaaa ctgcagatgc
     8101 tcgtggacaa attgtgatgt tccattccaa agatttacta acttgggagt tttattccgt
     8161 attgctggag ggaactccag aacaaggcat tgtatgggaa tgcccagact tgtttgaact
     8221 agatggcaaa gaagtcttga ttctttctcc tattcaaatg actccacaag gcaatgctta
     8281 ccaaaatacg aactcaactg ttgctttcat cggtactgtc gattggcaaa caggcaaatt
     8341 tctagtagag aattttcatg aaatcgatgg cggtttagat ttttatgcac cccagacctg
     8401 tgaaaacgaa gcaggccaaa gaataatgat tgcttggatg caaatgtggc agcgtaaaat
     8461 acctacgaat gatctgggcc atggttggtc aggttccatg accttgccta gagagctgag
     8521 ggtggctgat aatcaattgt tgcaacggcc agtttcatca atttatcaag taattgatcc
     8581 gcagaaaagg attgaatggg cgaagactga agagaatcgc ttcttactga aggacttagt
     8641 atatgaccag cactatttac gcttggaaat caatttaaaa caggcaacga aactagaact
     8701 tcactatgcg aagggacccg accatacatt actgcttaac tatgatgttg aacgggagtg
     8761 ctttactgct tccagggaac acatgccgta tgatttatca ggagctgaaa aggaagtgtt
     8821 gaaaaagcgc agtgtgacga ttcctttgga aaataattgt ctaaccatcg aaattttccg
     8881 tgatacttca gctattgagc tttttctaaa tgatcgtctg actatgagta caacttttta
     8941 tgagacagaa aaaggacagg attttctttt gctggcagac agtgaagtaa ccttttcatt
     9001 ggaaagcggc ttaattaatc tatagaaggg agagctcagt gatgatttat ggttcaatcg
     9061 aagcaggcgg cacaaaattt gtgtgtgcca ttggcgatga agaaatgacg atcaaggaaa
     9121 gagtgagctt tccgacaacg acacctgagg aaacaatacc tttagtcatt gacttcttca
     9181 aacaatacca agcagattta gcagggattg ggattggctc atttgggcct atcgatatcc
     9241 atcgcgattc cgccacttat gggtacatta cctcgacccc gaaa
//
LOCUS       DAPBBV010000075         8236 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.077, whole genome shotgun sequence.
ACCESSION   DAPBBV010000075 DAPBBV010000000
VERSION     DAPBBV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.077"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="RD486_002623"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="RD486_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDT7664322.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="RD486_002624"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="RD486_002624"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HDT7664323.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKNSSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="RD486_002625"
     CDS             2591..3376
                     /locus_tag="RD486_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7664324.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="RD486_002626"
     CDS             3389..4240
                     /locus_tag="RD486_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HDT7664325.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="RD486_002627"
     CDS             complement(4364..4816)
                     /locus_tag="RD486_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7664326.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="RD486_002628"
     CDS             complement(5281..5649)
                     /locus_tag="RD486_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HDT7664327.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="RD486_002629"
     CDS             5799..6281
                     /locus_tag="RD486_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HDT7664328.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="RD486_002630"
     CDS             6318..7328
                     /locus_tag="RD486_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDT7664329.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="RD486_002631"
     CDS             complement(7443..8156)
                     /locus_tag="RD486_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664330.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2788 a         1337 c         1669 g         2442 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa acagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtcta tggata
//
LOCUS       DAPBBV010000076         7891 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.079, whole genome shotgun sequence.
ACCESSION   DAPBBV010000076 DAPBBV010000000
VERSION     DAPBBV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.079"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..239
                     /locus_tag="RD486_002632"
     CDS             <1..239
                     /locus_tag="RD486_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7664331.1"
                     /translation="KENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIF
                     QSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
     gene            complement(279..971)
                     /locus_tag="RD486_002633"
     CDS             complement(279..971)
                     /locus_tag="RD486_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7664332.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1408..1977)
                     /locus_tag="RD486_002634"
     CDS             complement(1408..1977)
                     /locus_tag="RD486_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7664333.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2051..2374)
                     /locus_tag="RD486_002635"
     CDS             complement(2051..2374)
                     /locus_tag="RD486_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664334.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2528..3340)
                     /locus_tag="RD486_002636"
     CDS             complement(2528..3340)
                     /locus_tag="RD486_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664335.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3694..4542
                     /locus_tag="RD486_002637"
     CDS             3694..4542
                     /locus_tag="RD486_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDT7664336.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4687..5628
                     /locus_tag="RD486_002638"
     CDS             4687..5628
                     /locus_tag="RD486_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HDT7664337.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5618..7789
                     /locus_tag="RD486_002639"
                     /pseudo
     CDS             5618..7789
                     /locus_tag="RD486_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2379 a         1539 c         1417 g         2556 t
ORIGIN      
        1 taaaagagaa taacattatt caaagcatgt ctagaaaagg aaattgctta gataattctg
       61 taatagaaaa tttttttggt gtgcttaaat cagagttttt ttatcgagaa aaattccgat
      121 caattgagat atttcaaagt aaattaaatg agtatattag gtggtataat aacaaaagga
      181 taaaactaaa gttaaatgga ctatctccag tagaatatcg gaaacagtcc attaaatagt
      241 tcaacttttg gggttcagtt caaagagggg gggatttttt atcgttgtgg aatatttaaa
      301 taccaacgct tgtcatgaaa atcttgtgct ccacccttag tatttccttc tggatcgttt
      361 gtcgcacgca tcatgacgta tactttctta ttagggaaat cacgcatatt gaaagataca
      421 tgatagccaa catttcctaa agtattataa gcttgattta cgtctggtct ataaatccca
      481 tcagctctta ctctagctag ttcttttcca gtattgtagt ccataatgaa aatatactcg
      541 tatttataat tagcaatgtg ccatccagct acatgcaagt ttgcgttttc gatttctccg
      601 aactgatcaa tgtgggcgta atttgttcca tctgtcagcg tagaatttgc agcacctgct
      661 cgagttggat caattactgg tttatcctcc gaagtagttg gattatcatc cgtaaaacca
      721 tgagccaaat cataggctag tttttcttta cttacaccta tttcagaaag ataaccgtaa
      781 ggatctgtat gatcgcccca aatattttgt gttacccata aatgcgattt gattcctggt
      841 tggttataag gagtgtctaa tgttaatgga ataccatatt tcattgctga atctcttgcc
      901 aattcaacgt atactttata gttcttttca aaagtttctt tatcatgtgt gtgttgtaac
      961 tcgatttgca caggactttt ggctcacgag gttgtcctac tctacatctt gctgatagat
     1021 atgctgaaag gaaaacacca acattatgtt ttgctttttc agctagaacg agacaagcag
     1081 gaataccttt agaagatatc aaaggttttt taggtcataa agatgtttcc actacacaag
     1141 tctatgccca tatttctccc gaagtgaaaa aaagatcaat gaatcaacta gaaaactata
     1201 tagaagagca aataaaaaag cactcaaatt gagtgctttt ttaagctcac tatcactaaa
     1261 actatcacta attttattta taagcgaaca tgtttctatc actgattttt taaatctagc
     1321 gaaaaaccct tatcttaaag gcgttcgttc aattctttgg caaggtcttc aaagcctggc
     1381 ttgcctagaa gtgcgaacat ggttttctta tagctcatgt agaaaaattt tcttgatgat
     1441 gattttatcc atcaattgag attgactgtt ttgctctcct atgatttcag ctatgattgt
     1501 ccgattttgc ggttttcttc ttaactggta gttgattttc ccagtttcca tcaactcgct
     1561 aagcatatcc acgactccgc caaatccggt ctttttcgta ataaaaccta gtgctaccat
     1621 tcgttcatct agattttttg ctgtaatcgt cacaccagta atgagcgagt gctgtaatgt
     1681 ttgggccagc tcttccatcc cttcagcatt ggatacgacg gaagctgttt tgttaatagg
     1741 ttcttcgttt atttcttttg gttctttcct ctccactttc actgtttgac gaaggacatc
     1801 tagttcttgc aagagcgttt cgtattgttc ttgggtcagc atcacgccag ctactttttc
     1861 acgattaaat atatatacgc cagttcccgc gtctcgcgct tgagcaaata catccatcgg
     1921 cgatcgtttc acttctgtga tcgaagatgt gggaacttct aatttcttta attccaatgg
     1981 atttcctcct ttactaatcg ctttttatta tagcacagac tgacttgttt tgatcttttt
     2041 tccaaaggtt ttatcggttt ttgcctaacc agtaattgat atcggtaaga agtctttcga
     2101 taccaaatga aggatggtac agatacgttt tttgatcttc gttatggtct agtggaaaaa
     2161 aatgatcgat gatcactaga tctgcatacc gaggcggctt atttcgagta catacatgta
     2221 tagagatccg ttttcgatgt cttagcgttt tgttcagtac cccagcaagt cttcttgctt
     2281 cttggtgttc atagcgaaaa aaaaagacga ttttcacttc aggagggtgg acatctaaat
     2341 accctcgttc ctggagtgtt ttcagtaaaa gcatccccca ctctactgcg gggtgtgcaa
     2401 gtgcttgttg gatcgctagc cgaaattgat atagtttatc tttggaattg ggaaattttt
     2461 ctaatgtttc ctgataataa cgaacttctt ctatcagccg gtcatggata ccaattacgt
     2521 aacgaagtca ttcttggtaa agtacttttg tcagctttga tttgctttcg ctctcaaatt
     2581 cgctattcag ccaaaacagc gaatcaagct tttcagtcac aatcgtcaat ttccgatagt
     2641 cttgtgtctc ttctatccgt ttccaccgct tttcagtaat ctggttacag ctcaagcgca
     2701 aaattgctag ataatttttt tcttttattg gcaaaatctg ctcctctcta aatagcaatt
     2761 caggaaacaa ttcaaagaat agtgttcgac tgtctcctaa aatctcgatt tctgccggat
     2821 cctttctttg cttcaataat tggatgaaca tctcagaaaa ggactgctct ccatcatctg
     2881 caaaaaaatg cggaaaatct ttcaaaaagc aaaacagcag atatcttact tttctttctg
     2941 aaccaaagat ctgtgctttt ttataagaaa aagaaaggtg gtactcgcca aaccactttc
     3001 tcaatcgctc ttgcgtagaa cgatcgtact tctgctcgta aggttcattc aatagcagat
     3061 ttttcagtaa acaaaacggg ggtgattgga tcagaaaaac aaacaagaga taaggttcgc
     3121 tatatccttg atcataaact aactgaacgg ttttcttatg aagaatcagc tgaatgggac
     3181 agtcgctttc cgccaaacgt ttcagatgcc gatccactgt tttaacatcg attttcagtt
     3241 cttcagctaa atcagctttt cgccagatca aatctttcat tagattgatt agtgaaaata
     3301 aattctgtgc attttttgat aatagttttt gccatctcat cgatcatttc tcacctgatt
     3361 tctaaacata ttgtttgatc aaaatgggtt cactcctaaa aagataaaaa actccctttc
     3421 tatttattta aatacgcaaa tcttcctcat tattttttat tttactcaat ttaatcgtat
     3481 tctcatttca aaacgaatgt actttaaaaa aacataataa gatcactttg cttgtaggat
     3541 gtattccctt ccattacaat gaaataaata gcgattttat gagaaggtga tgtgaaaatg
     3601 gaagaaaaaa tagaagaatc caaacaaaaa atcgatcagt tgatataaga attagaaaaa
     3661 gcggtcatcg gcaaacgttc aactatccaa ttgatgatcg tggccctatt agcaggtggt
     3721 catgtcttat tcgaagatat tcccggtgta ggtaaaacgt tactggtcaa agcactagca
     3781 aaagctgtac agggaacctt cagcagagtc caatgtactc ctgatctgct gcctagtgat
     3841 attcttggtt tttccgtata caattcacaa tcaaaagagt ttgaatttcg tccgggaccg
     3901 atctttacca cgatcttgtt agcagatgag atcaatcgta cgactcctcg tactcagtca
     3961 gcacttttag aagcaatggc cgagaatcat gcaacgatcg acaacaatac ataccctcta
     4021 gacaatcatt tttttgtctt agctacgcaa aatccaatcg agtacgaagg aacatatcct
     4081 ttgccggaag cacagctcga tcgtttttta ttccgactac aaatcggtta tccttctttt
     4141 gatgacgaac ttttgctact tttggataaa ttcgaaaaag tgttggataa cttaaatgaa
     4201 gtattgaaca gttatgaaat agaagaaata aaaacaaatg tggcgaatgt ctttgtcagt
     4261 cccgaagtgg catcttatgc cttgcagtta gtgtcagcaa caagaagtca tgctgccatc
     4321 cagcttggca tcagtccacg aggaagcctt tcctttattc aggcagcaaa agcttatgct
     4381 ttaatccatg ggagaaatta cgtcacgccc aaagatttgc aggatttagt tccttacgtg
     4441 ttttcccatc gcctgatttt ttacgatcgt tcattgaagg aagacgaaaa gaaacaaatc
     4501 attcatactc ttgttgcaca aattcctatt cctgtgaggt agattgaggt agacaatgga
     4561 aaaaatcaaa gattatttca ttaattttgt gttatttctg gtatatttca tcattgtgct
     4621 ttttgctctt gtattcaaca attctttagg ctggttcttg ttggcctttt ttactcttta
     4681 tgtatcatgg agcttgattt cattaagcag ctttctaaag aaactttcgg ttacttgtac
     4741 attgcagcca ctcgtttatc gcaaaaaaag tatgcaggtt attttttcca tagcaaaaaa
     4801 gagaactttt tctttacctc tccctcgttt acaaatcggc ttcccagcaa tctttgcaga
     4861 aaaaaacaag agattttgat tcttacaaat aaaccgcaag aagtccaatt gctttggcag
     4921 ccaaaagaaa gaggatgcca tgaaacatta actgtcattt ttacagccta tgatagtcta
     4981 ggacttttca gaaaaagtgc aaaaagagag atctcttttc ctgtgactgt tctgcctgct
     5041 ttttgtaaga ttcaagcaga aaaattacag agagttctgg aaaaaaaaca gcagctgaac
     5101 gcgtaccaaa gaggtcttga ttttcgggaa catcgcgctt atcgtccagg tgattctttc
     5161 aaccgaatcg attggaaatt gtctgctcat actcaagagt ggttataccg tgaatacgat
     5221 tatcaagaag aagaatgttc tcctcttttt tgcttttggg gttcgcccag tccaaaattt
     5281 gaacctctgc tagacttgta tttttcttta tggcatttga gaaaagaaaa gcagccggaa
     5341 cttctgatat taggcaaccg cgcctttcat ggcaaagacc ccggtcatac ctattttgct
     5401 tctttggaag ctggcgatga gaaaactttt ttcgcacact tgaaaaaata tgcaaaaaaa
     5461 caaatcgtcc tctttgttcc tgagaattct cctgaagtct cagaagctat tgaaacattg
     5521 tcaaaagatc gaacggttta tcttgtttat ttcgtagaaa aacaactcat ggtccaagaa
     5581 aaagacaaga tatgttcatt gccaggaggt gaatggattg acgattaaac gggaaaaatg
     5641 gctgcgtggc gtttactcct ttgtgatact aagtgtaggt gctccgatat ttgtagtagc
     5701 taatcaattg caaaacagct accttcttat cctaactatt ggtgtcctat gccttattgt
     5761 ctgctgtatt cctaaaaaat gggtacgttt gctgctttct ttgccagtaa tgataggttg
     5821 tttgttttta tattttcctt cgaagacatt ttccatatta tggatcttac agtttttttc
     5881 gtcagttaca gaggaattct tccatctatc ccaaggtaaa ctttattatt tgccagaaaa
     5941 gacagctttt tttctcataa tgttgctgat ctatttattt attacattga ccgtggatta
     6001 cgactattgg tacgcaccct ttctttcttt gatggcttac ttcatgatgc ttaccgtttt
     6061 tcggaaaaaa gatttactgt acgaaatgat tgcggtagta actgttttgt tcgtgtatct
     6121 ggcagcaagg caatttttct ccatccggtt gttgtcgaga aacactcgat tccagtcatt
     6181 gactacagtt ctgcttattt gtttcttaac ttttagcgct atcttgcctt tatatcttcc
     6241 gaaagtacac caatctctcg aggaaacgag tgaaccgatc cgagaatatc ttaatgatga
     6301 agggctttat gacacactcc atgagtatca attaaccgga agtgcaagaa caggcttcag
     6361 tgagaatgat gaacagcttg gtggaccttt atatgataat ggcgaagttg tttttacagc
     6421 gaaccaaaaa ggaaatggct attggaagat cgaaaataaa aatcattaca ccggttctgg
     6481 atgaatagaa gatcaggacg cacccatcca accaatccaa gaattccctg ttgacatcac
     6541 gagctaccaa accgttatag aagacaaaga aaacattaca ttgaccctaa aaaaacaagc
     6601 tttcttacct tatccttatg gaaatactac cttgactgat ttttcattag ctagtggaca
     6661 aacgctttac tatttgcctg aaagccagcg attcattcct gtcccgaatg aatcgacacg
     6721 ttctgcaact ttacaaacag aaaggttagt ttttacgaga gaagaattaa aaagcagtca
     6781 gttaaaagct gatgatttag aaaatcagca gacaaatctt caattgccaa aaagtttgcc
     6841 taaacgtatt gaggacttgg cggtcgaatt gaccaaaaat gaagcaactt taattcgtaa
     6901 agtcgaagct gtctaacagt atttaaaaac aagcggaaat ttccgctatt ccaaaacgga
     6961 taccgggcat actccaaaag aacacgatta tgtggattat ttcctctttg attcaaaagt
     7021 cggctattgt gacaactttt caacttctat ggtcgtcctt cttcgaacac ttggtatccc
     7081 agctcgctgg acaaaaggtt ttacaaatgg gctcagaaca ggcacagata atcaagggaa
     7141 tgaggaatac agcattctca atagtcatgc tcattcttgg ccagaggtat actttcctgg
     7201 atttggctgg cttccatttg aaccaacccc ttcatttgcc aatccaatgg gttcacaacc
     7261 agttgctgaa acaaccgaaa ccgtccagcc tgctatcgaa caaccaaatg aaagcgaaaa
     7321 tatggcagaa actatttcca gtgagagatc tgaggtcatt ccatcagaag aaacaacact
     7381 cacaccagct tataaaatcg tcttattcag ccttggagtg tgtttatccg tcttgttgtt
     7441 ctttctattg ttattcagaa aatctctgcg ctggacaagt tatcttatct atcttcattt
     7501 ttttgcttct actaatacga ttgcatatca aaaacttctt aaccctttgg aaacattggt
     7561 accgcgcaaa cccgcagaat ctttgcagga atatagcctg cgaatagaac aagaattcaa
     7621 gctagatctg cgtttcattc gattaactac tcaatatgaa gcagaaatat atggacgaca
     7681 agcagatccg gtaaaattcg ataaaaaaac ctatttagaa ataacgcata taataagaaa
     7741 aacggtatac aaaaaaattc tgacaaaagg gagccgcttc aaaaaataag ataaaatttc
     7801 tggagaatct acttctcgaa tgccgagaac cagctgattg agtatcgatt actcgaaaaa
     7861 aaggttgtga cacgtttttt gtcacaacct t
//
LOCUS       DAPBBV010000077         7760 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.080, whole genome shotgun sequence.
ACCESSION   DAPBBV010000077 DAPBBV010000000
VERSION     DAPBBV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.080"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="RD486_002640"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="RD486_002640"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HDT7664338.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3285)
                     /locus_tag="RD486_002641"
     CDS             complement(2032..3285)
                     /locus_tag="RD486_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDT7664339.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="RD486_002642"
     CDS             complement(3291..4214)
                     /locus_tag="RD486_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDT7664340.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="RD486_002643"
     CDS             complement(4435..6927)
                     /locus_tag="RD486_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDT7664341.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="RD486_002644"
     CDS             complement(6934..7401)
                     /locus_tag="RD486_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDT7664342.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="RD486_002645"
     tRNA            complement(7537..7610)
                     /locus_tag="RD486_002645"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="RD486_002646"
     tRNA            complement(7668..7741)
                     /locus_tag="RD486_002646"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2162 a         1691 c         1246 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acaaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DAPBBV010000078         7598 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.081, whole genome shotgun sequence.
ACCESSION   DAPBBV010000078 DAPBBV010000000
VERSION     DAPBBV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.081"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(941..1354)
                     /locus_tag="RD486_002647"
     CDS             complement(941..1354)
                     /locus_tag="RD486_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HDT7664343.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1810..2295)
                     /locus_tag="RD486_002648"
     CDS             complement(1810..2295)
                     /locus_tag="RD486_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664344.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2434..2649)
                     /locus_tag="RD486_002649"
     CDS             complement(2434..2649)
                     /locus_tag="RD486_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDT7664345.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2873..3673
                     /locus_tag="RD486_002650"
     CDS             2873..3673
                     /locus_tag="RD486_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7664346.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3692..5560
                     /locus_tag="RD486_002651"
     CDS             3692..5560
                     /locus_tag="RD486_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDT7664347.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5553..6044
                     /locus_tag="RD486_002652"
     CDS             5553..6044
                     /locus_tag="RD486_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDT7664348.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6032..6586
                     /gene="srlA"
                     /locus_tag="RD486_002653"
     CDS             6032..6586
                     /gene="srlA"
                     /locus_tag="RD486_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDT7664349.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6604..>7598
                     /locus_tag="RD486_002654"
     CDS             6604..>7598
                     /locus_tag="RD486_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDT7664350.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2235 t
ORIGIN      
        1 tgttactatg aataacataa taagaaagta aagtggattg atttgagatc tttttatact
       61 tcaaaaaaga taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta
      121 atacatttta atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag
      181 agagatcata agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc
      241 ccatatttct tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat
      301 ccagcaccat ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg
      361 aagtaaaaac aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc
      421 ccccacattc aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt
      481 atgaataaca gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga
      541 agtttatttt tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa
      601 gccgatttcg tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt
      661 atggataaaa tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa
      721 taagtaaaag aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa
      781 gacaatcaaa tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt
      841 aaaaacaaaa tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat
      901 atataaaaat cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt
      961 ttgtttcttt tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa
     1021 aggttccagt gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga
     1081 ccgaatgtct ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat
     1141 gattggcgga gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac
     1201 agccaggcat atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg
     1261 gataacttga aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag
     1321 ggaacatgtc gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt
     1381 ttttatttat ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt
     1441 agctttgtga atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg
     1501 atcattaaaa taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca
     1561 aatatagaaa aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac
     1621 cgaaaatgaa gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc
     1681 ataagagaaa tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta
     1741 taactttctc agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat
     1801 atcatctaat caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga
     1861 cactcgataa aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc
     1921 tgtgaacaaa taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg
     1981 taattcggaa cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag
     2041 agaaggtaca gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact
     2101 tgattggcta tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga
     2161 agtactttta gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga
     2221 attctttgtt ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta
     2281 aatcccttta tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt
     2341 aaacaaagaa aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat
     2401 gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt
     2461 aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat
     2521 cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa
     2581 gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa tagcatctaa
     2641 agttttcatt agaattctcc tttcttaaat gataaaacaa ttatatatca aaaagagaaa
     2701 cattgcttat ataacgctca ggaattttag caatctatgc aaaaagatga aaattttttt
     2761 tgctcttcca ttagtacaca ttttttagct gaagctgtaa atttcatgtc ttaatttttt
     2821 ttagtgagct tttatactgg atttgtaaga aaaaagaagg agaggatcac atatgtcgga
     2881 ttggttggat attgcaggaa aagtagtaat tgtaactgga ggttcctcag gaattggaag
     2941 aagtatcgtc gaaaatttgt tgaagcagaa tgcacaagta gcgaattttg atgtaactga
     3001 atgccgtata cagcatgaaa acctactatc tttaaaagtc gatgtgtctt ctaaaacgga
     3061 catagaagaa gggatatata aagtaatgaa acatttcaag acgatcgatg gtctagtcaa
     3121 taatgcagga ataaatattc cttctcttct aatagataga aatcatccaa aaagcaagta
     3181 tgaattatca gaacaagttt ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt
     3241 gatgagccaa gcagttggaa gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct
     3301 ttcttctgaa tcaggattgg aaggatcaga aggacagagc tgttatgctg ctacaaaagc
     3361 agcgatgaac agttttactc gttcttgggc aaaagagtta ggaaagagga atgttcgtgt
     3421 ggtaggtgtt gcaccaggga tactggaaga aaccggtttg agaacacaag aatatgaaga
     3481 agctctttct tatacgagag gtataagcgt cgaacagctg agaaacggtt acagtcgaac
     3541 aagtacgatc cctctaggaa ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta
     3601 ttatctttca gaaagatcaa gttatatcac tggagtcacg actaatattt caggaggtaa
     3661 aacaagagga taaaggatag gggggacgca cgtgacgcta gtaaacagat ggtaccaatt
     3721 attgaaatta ctagtcactc acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa
     3781 aaccagtaat caaaccataa aaaaagatat tggggagttg aatgaagaaa ttgccggtat
     3841 tgcaaaaatc atccaaaaaa acaaacattt tgaacttgaa atttatgatt ttgatttttt
     3901 tgatgagatc atgcaaggaa aattgaaaac agccagtgat ttcaattcgg catccaaaag
     3961 aatcgcttat ttactaaata ggctgatcga aacagaggat ttcttacgta tggatgattt
     4021 gtctgaagaa gtcggtgtca gcagaggaac agtggtcaag gatctaaaga cattaaaaga
     4081 gatgatcaat gattttgatg taaagattac aggcacacca aataaaggac taagaataat
     4141 aggagatgag ctagaattac gactactttt attttatttt gtttctccct acttttcaga
     4201 gacgaaaaca gaacagtttc tagaagaaaa acaagcaatc aaacattttc agaagaagac
     4261 gaatgctagt aaacaagaaa tcaccctttt aacgaaagtt atcggtattt ctttgaatag
     4321 aatctctagt aactatctgt tgaagaagcc catcaatcgt tacagtgggt gttttgaata
     4381 tatccaagaa ttcaatgaac tgatcaatca gttggaagaa atctatgaac taactttgag
     4441 ccaatatgaa aaagatttta tcagttttcc tttgaacatc atcaacacaa gtataacgat
     4501 gataaggaaa gctaactctg atttgcgctt atatttcgac cccatgatga tgcgtattcg
     4561 acgattagat ctcattgatc tggatgagtc cttcttatat caagagatga aacagcacct
     4621 ctctttattg ataaatcggg taatttttcg ttatcgattg actgatttat tttatggtga
     4681 gatagaaaaa aagtatcctt tttcttacca aatcgctagc gaatgcatac aagcattaga
     4741 agctatcttg caacataaga tctctaaagt agagatcagc tacctaacgt tgtatttgga
     4801 gttagcattt cgatatcaaa aagagcattt ttcctctaaa aaagtagcca ttgttcatac
     4861 gacaggaaaa ggaacagcat taatgatcca aagacaaatc aaaaggatat tggggaggga
     4921 tatacaaata acacatgttt cagaagaaca atatgaaaaa gtagatctaa acaaatattt
     4981 cgctgttttt acaacgattc cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt
     5041 gactaatctt tttgatgact cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg
     5101 attagccggg tttcattcta ctgttttttt ctatcaaata tggaaagaaa aaaagacgta
     5161 tcaagaatat ttaaacaaat tagtcgctcc tttgatcaga ggctattatg tggatgaaga
     5221 atttgaaaaa aggatcttga aaagagaata tcagcaaagc acatttgtta acaaagaatt
     5281 tgcttttcct cacacaacca accagctatc tcaacacatt gttttatcag tagggctaat
     5341 aactgatcaa ggtttagcag aaacaggagg aaatggagtt atttttttat ttgccatacc
     5401 tgaagaaatg acggctgaag ttgagaatga attatttgag ctatacgata tcctatttga
     5461 actcataaaa atgggaatag atgagtttat tgaattagca ccgacacaag aatcattttt
     5521 aaaactaatc aaaagtaaag gagagagact tcatgaatga tatgtatcta ttcatagttt
     5581 tcgcagcttc agcttatgtg ctgcaagcag ttatcagttg gaagcaacta aagcatttca
     5641 atcaaacata tagcgaactg cgaagaaaag gaaaagtagc gattggtaaa cgacctggga
     5701 aaatccgttc aggcacgatt gttatgctag ctatagacga tcatgatcaa gttttagaag
     5761 tcagaaaaat gcaaggggtt acatctttgg caaaatttca ttcattacct gtctatgcgg
     5821 gtgaagatat ccattacatc gatcgttacc atccctcagt tcgagcggaa gatcgtttga
     5881 cacaagcagc tttagaaaat gccagagaag tatacttacg aatagaggca ggaaatgaaa
     5941 aaagtgaaca accttcattg ccttttattg ctatgctcaa taattttcgg atatggaaaa
     6001 gtacgatcaa agaaaaaagg agtgacaaac gatggatatc ataacaaaat ttgctgaggg
     6061 atttatgagg ctgttccaaa caggtgcaga aacattcata agctggatga caggaatcgt
     6121 accagttgtc ttgatgctga tggttgcaat gaatacgctg attgcttttt taggtgaaga
     6181 ccgagtaacg aaagtagcca aattatcagc gaaaaatccg cttactcgtt accttgtgtt
     6241 accgttctta tctgctttta tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct
     6301 tccagaatac tacaaaccaa gctattatgc tgctcaagct caattttgtc atacgagcaa
     6361 tggtgtattc ccccatatta atcctggaga attgtttgta tggatgggga ttgctcaagg
     6421 gatcgaaacc ttagggctaa attcgatgga gctggctatc cgatacttgc ttgtgggact
     6481 gctgatgaac tttattggtg gttggataac tgattttact actggatttg tatgcagaca
     6541 gcaaggaatc gttcttagca aaaaagtaga gctttcagtt gattagagaa aggagagttt
     6601 taaatgtatg gtgatattaa gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt
     6661 attaggccga caaaagataa acacaagttc atctatgtca caggtggagg tgagaggcca
     6721 atgatcgtag ataaaataga agaactgaca ggtatggagt ctatcaatgg gttcaaaaca
     6781 tcaatacctg atagtgaaat cgcgcttgca atcgttgact gtggagggac tcttagatgt
     6841 ggaatttatc ctaaaaaagg gataccaacc atcaatatcg tttccacagg aaaaagtggc
     6901 ccattagcac aatatatcac tgaagatatt tatgtttcag cagtagggtt agaacaaata
     6961 cagccactaa tggaaactga tgataacaaa gaaacagtaa atactgcatc tccagataaa
     7021 aagtacaaat atgatacttc taaaaagata accgagcaaa aagcagagca gcaaaactgg
     7081 atagcaaaaa ttggaatggg cgcgggaaaa gtagttgcta cattcaatca atcagcaaga
     7141 gaagcagtag atacgatgat ccggacagtg atccctttta tggctttcgt ttcccttttg
     7201 attggtgtga tacaaggttc tgggatcggt aatgtatttg ctaacattat ggcaccttta
     7261 gcaggaaatg cagttggatt aacaatcatt ggctttattt gttcactgcc atttttatct
     7321 cctttgcttg gtccaggggc agttattagc caagtgattg gaacattgat cggtgtagag
     7381 attgggaaag gaaatattcc tccccaatta gcattaccgg cactatttgc tatcaatact
     7441 caaaatgcat gtgattttat tccagtcggt ctaggtttgg aagaagcaaa agctgagaca
     7501 gtagaagtag gtgtaccatc agttctttat tcaagatttc ttaacggcat cccacgagtt
     7561 atcattgctt gggtagcaag ttttggatta tatagctg
//
LOCUS       DAPBBV010000079         7367 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.082, whole genome shotgun sequence.
ACCESSION   DAPBBV010000079 DAPBBV010000000
VERSION     DAPBBV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.082"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(99..1229)
                     /locus_tag="RD486_002655"
     CDS             complement(99..1229)
                     /locus_tag="RD486_002655"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDT7664351.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="RD486_002656"
     CDS             complement(1878..3080)
                     /locus_tag="RD486_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7664352.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="RD486_002657"
     CDS             complement(3140..3343)
                     /locus_tag="RD486_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HDT7664353.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="RD486_002658"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="RD486_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="RD486_002659"
     CDS             4880..5692
                     /locus_tag="RD486_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7664354.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="RD486_002660"
     CDS             complement(6716..6868)
                     /locus_tag="RD486_002660"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDT7664355.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..>7367)
                     /locus_tag="RD486_002661"
     CDS             complement(7059..>7367)
                     /locus_tag="RD486_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7664356.1"
                     /translation="LGVKGQNLLADDSFWQIEAFYLAQCAYNTTLMFSPDRIIFGGGV
                     MKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGIIGGLALARKAVRNKQP
                     "
BASE COUNT         2268 a         1477 c         1133 g         2489 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaa
//
LOCUS       DAPBBV010000080         7158 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.083, whole genome shotgun sequence.
ACCESSION   DAPBBV010000080 DAPBBV010000000
VERSION     DAPBBV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.083"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(560..1600)
                     /locus_tag="RD486_002662"
     CDS             complement(560..1600)
                     /locus_tag="RD486_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDT7664357.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1949..2275)
                     /locus_tag="RD486_002663"
     CDS             complement(1949..2275)
                     /locus_tag="RD486_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664358.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2262..3065)
                     /locus_tag="RD486_002664"
     CDS             complement(2262..3065)
                     /locus_tag="RD486_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7664359.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3418..3708)
                     /locus_tag="RD486_002665"
     CDS             complement(3418..3708)
                     /locus_tag="RD486_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HDT7664360.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3844..4023)
                     /locus_tag="RD486_002666"
     CDS             complement(3844..4023)
                     /locus_tag="RD486_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664361.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4020..4370)
                     /locus_tag="RD486_002667"
     CDS             complement(4020..4370)
                     /locus_tag="RD486_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664362.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4363..5688)
                     /locus_tag="RD486_002668"
     CDS             complement(4363..5688)
                     /locus_tag="RD486_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDT7664363.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6138..6752
                     /locus_tag="RD486_002669"
     CDS             6138..6752
                     /locus_tag="RD486_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7664364.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6917..>7158)
                     /locus_tag="RD486_002670"
     CDS             complement(6917..>7158)
                     /locus_tag="RD486_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664365.1"
                     /translation="SFMYRDFYEESIELTPTEPNKSQITLSKELERKVESQELAIGIS
                     ITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
BASE COUNT         2188 a         1292 c         1062 g         2616 t
ORIGIN      
        1 ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc ttaatgcttt
       61 cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc tttctttttt
      121 ttgtattttc aattatcaca atttatcgtc caaaagtgca gaacgaaaat caattcatca
      181 caagcatatc agacaattaa atttaaaaca actaaaaata tacaaaaaag tgtaattgaa
      241 tattagcagc actgcctgaa aagaagtaat atcaggcttt tcagcttggg gaaataagtg
      301 aattacctct cttcatgaat tattataact caaaaaagca catatgcaaa cactagttcc
      361 ctattttttt gaatgaaaaa taactaaaat atctaacgat tatgacttta aaacctacgt
      421 ttgtgattgt tttcataaac ttttaatcta aaaactccgg aataatagct atttatttgt
      481 aacatttgta ataaaattaa aatcataaaa aagttctaat ttaaaattga tcatttttat
      541 agtgatcgct ttttatcaac tactctagcc aattttccgt actaactgtt ggtaattcgt
      601 taaatgtttc tctttgttcg tttgcaagct ttgccgcaat agctttttcg acaaaccaat
      661 tttttacata aacgaaaatt agattctgca aattgtttac tttttcagtt ttttgttttt
      721 gataagcttt cagcaaagtc atatataatc ctttgtcagc atcaattcca taagattcca
      781 gttcttcata aacaacaact gtttgctcta attcttcagc ttttttcttt gcattatgaa
      841 tagtttggac ggttttttga gcgtcttcgt aagtactaga aaatgttttt atcaagttta
      901 atacattttc tggtacaaat gtatttatac tgtcctcttt catgatgtcg acgaagttat
      961 ctagtaaaac ttgattttgt aactgatcag tttcagtgtc tattatgtgt ctattagtgt
     1021 ctatagaatt agaatagaat agattgtctg cgattttcgc aattacggtt gagtccttga
     1081 tatgactgga ttttgccgta tttgcgattt tcgcaattac ggtggtatca ttgatttctc
     1141 gcggttttgc cgtatttgcg attttcgcaa ttacggtggt atcagtattg tcttcctctt
     1201 ccatgatttt aaagacgtct tgattcgtta cttctggctt gcctaagtac aataaattag
     1261 gcatggattc aatcttaccg tcacgtttat ttactcttcc tctcttctgt ttcagaagac
     1321 ctgctttttc taattccttt ttgattttag atactttacc ttcgcggcat tgtaacaatt
     1381 tcattaattc ttcaactgtg aatatgaaaa atatattatc atcagaatct acccagttat
     1441 ttttgactga ataatcaaat cgatctttaa gtagcatata agcaattttt gcatcatttg
     1501 atagatccat gtatttttcg ttagtaaaaa ataccttagg catttgataa tatttttcac
     1561 gataaatttc ttttgatttg taataattaa aatcattcat agccaatcct ctttctgtag
     1621 gatagcgttt tgttcaaaac tatgttacaa tgaattaaac aaatatatct atccactata
     1681 tatttttcta ctgctgataa gtcgccaaac tttgttaaag cagtagtctt tttttatctt
     1741 tttttagttt accttaaaaa ataaattaaa gcaaaccgct ctatttcaag gtttaagctc
     1801 atagtaacta tatcacgata ttacaataat attatatcac gatatcgtaa tattacaata
     1861 tgaagataag cgacttatca gctttgatac tactgatttt tataaaaaaa atatcacgat
     1921 attatgatat cgtgatattg aatgtaaatt aaattttatt ttgtttcttt gctagtttat
     1981 atccttcaat caagtattct tcaggtatgg actttaatag cgcatcttct ataacgtctg
     2041 gtttactttt gtctgattca gcaatagtcg tccaatattt gagtgctgac attagaattg
     2101 gatttatacg aatgctatct gctgttctta cactacttcc ttgatctttt atgactttac
     2161 ttatattttt cttggttaat tcgatttctt ctacttcttt tgatttaaaa ttctttttat
     2221 ttttatttcc tagtaatcta cttactgcag cttgactgcg attatcttct gccatcaaaa
     2281 tcaccaactt cttttaaata ttcttctgta aatgctttat agtcatcttc agctgttgag
     2341 ggtttattaa aattgattag atctgatcca gcagcttgcg cttcgtcaac ggttattgtc
     2401 ctacgaatat aagttttgaa aatttttgca ccaatgactc tagaaatttc ggttgctgca
     2461 gacgtcattt ctttagaaat gttataacgc ttattatact tagtaaatag aactcctcgt
     2521 acttcaagct tgtcgttcgt atattctttt accgtttcaa tagtttcact taactttatt
     2581 agtcctttta atgagaaata cgcagcttca actggaatga taatttcatc agaaacagta
     2641 aatgcgttga ctgtaagcat tcctaaactt ggtggacaat caattataat ataatcatag
     2701 ttgtccttga ttggttgaag tactctttta agcctgtgtt cacttcctac ttgagtaaat
     2761 tccctctctg cagaagaaag ggctatgtcg gctggcaaaa catcaattcc tttatagtcc
     2821 agaatagcat ctgtaatgtc agcctcccct tttaatactt cataaattgt aggttggttt
     2881 gttccatcta tatcgaaacc tacattatct gtagcatttc cctgaggatc aatgtccact
     2941 aaaagtacat ttttaccgta aacaaatttc aaacatgctg ctaaattaac gctagtcgta
     3001 gttttagaaa ctccaccttt ttgattggct actgacaata ttcttgccat taaaatatcc
     3061 cccattcatc ttatattata atataattat atcataatat tgtgatattg caatatcgta
     3121 tatgcattat attgtaatat tgtgtgatta ttttgtttta aagatatata tcggttcgga
     3181 tataaagatt attcatatgt tattcgaaat taaaataatc actttttatt actttaaaat
     3241 tttttattaa tgataagaaa tatgttttgc gagcagcaac tagaataatt taaacattac
     3301 taaactgtct atattgttac taataattcc cttcttatag tgcattttct tagaaaaaaa
     3361 caatattacg atatcatgat attaagatat cgtaatatta tacaattgtg attgatatta
     3421 tatatgtttt tttatttttt tatcatgttt aatcttgaag gaatcatatt ctttttctaa
     3481 agacaggagc ttttcataaa catcagacat gtttaaacta gaggccaggc ttaaatcata
     3541 aacgaatgaa gcaggtaatg attttattct acgttgtcgg gttatccagc ttgcaaccgt
     3601 tccttgtggg taggcatata actcacaaaa ttgttctaca gtgattccta aattcttgat
     3661 aatgtaaaca ttgatcgggt gcgagtaaac aaatgtattg atagacatgg tgcgtaagcc
     3721 tactttcttt tattattgcg tttgcaataa tagtttaaca cacgcattat tctagtatct
     3781 actcctattt gtaaaaacaa aaaaggattc atagagataa ctctatagaa tccgtaaaat
     3841 accttatata tataacggga agatataaaa cctaaaatta tgataacctg ctgcagcttc
     3901 tacatagaaa gagaagcgct caacaccaac ctcatttatc aaacgttggc cataacccca
     3961 aatctcttct gatagctgat caaaggttat atactttagc tcatattgct ggataatgtt
     4021 cattctaatc gactccattt attatcctgg taaaattcga tatgacgtat ttcgtcgtag
     4081 tgaattttgt cttttccaac gtagatcccc agctcatcac tacctaagat cttgccaatg
     4141 atatcttctg gatagtatcc ttcagcgttt cgttcttctt tttgaataga tactgatcta
     4201 ttttttatga ctgcagcgtt caatacttcc gcaatctctt cagtcgtcat ttgttctttt
     4261 gctaaatttt gactggttcg ttgttcattg tcggcatcaa tttcttcagt atgatcagat
     4321 aaataaaacc ctgcccactt taaacgtcca cgatcattgt aatcaatcat ttttaattcc
     4381 cccatttccg cccgcatgac caccaacaag tgtgcttcta gtaatgcttc tagcgccttc
     4441 taacattgaa gaagcatgta caatcgacgt aaaaccatat ttttgccgaa tcttgtcaat
     4501 aattttatct aaattttctt cgtcaatttg cttttgtgga tcactaaata aatccagctg
     4561 aagcgaatcg gtgtacacaa gcttgctata ggttattcca acatgcctta cttcttgtcc
     4621 ttcataatac ttatcaaaca agaaaagaca ataattctgc aattcctttg tattatctgt
     4681 gatagggatc ttcatctggt gtgaaaaccc tggtctcgtt tctaagatcg acgtgccaat
     4741 gtgtaaatgg acacaacctg ttttacagtt atgctgccta atgcgtatcg ctacttgttc
     4801 cgccatttct tttaccacca gctcgatttc atttcttcta gtataatctc gtggtaacac
     4861 ttgtgaattt ccatatgatt tttcctttgt cggttctggt gggattgcta tatctgttcg
     4921 atcgatccca ttagcatgga agtacagctg taagccaatc acacctagtc tattcttaat
     4981 cgtataagga ttccagttag caagatctct aatgctcata atccccatct gattgagtct
     5041 ttttttcatt cgagagccaa ttccccaaaa gtccgtcatt tcaggaatat tccatacttt
     5101 ttcaggaacg ttttcgtacg tccattccgc aacaaatcct tcattatgct ttgcttcgtt
     5161 gtctaaggct agtttagcca aaaggggatt atctccgaca cctactgtag caatcaatcc
     5221 tagctcttct ttaatattct cctggatcat ttgagccagc ttctttctcc gttgacttcg
     5281 tgttccttca gtcgtaaaaa gattcagtga tcgggtcact tttaagattg attcatcgat
     5341 cgagtaaatc agtagatctt catcagccac atatcttctg aaaatattat ttacctgcat
     5401 atttcgcttg atatataggt tcatacgtgg tggaacaacg tgtagtgttt taggaaatgg
     5461 ttgtggtaag tcacgtggtc tactcacatt tgtaatacca taccgctttt ttgcttcagg
     5521 agaagaagct aatatcaatc ctgaaccagt attatcagct cgactcataa caacaagttc
     5581 tgttgttaat ggatctaaat ttctttctat acattcgaca cttgcgtaaa agcttttcat
     5641 atcgattaaa aagtaatcat ttactggctc ttttgaataa tccatcataa ataacactcc
     5701 attctttcac attatacaaa catatgttcg atattgtaaa gaagaaatag ctaaatacat
     5761 aaaaaaagaa gcataggtat gctatcaccc tgcttcttct tttgatttgt atgatcaatt
     5821 tattctatca ctttactaat taatttgaaa atctaataaa aactctcact ctaaaagagt
     5881 gagagactgc aaattagagt acggactttt ttggagttcc gttctttaat attaacaaat
     5941 gaataaaatc cttacaacat ttgagaataa gttatcagta gacacttaca aaaaattctc
     6001 atactatttc ctccatcatt agtttttgtc tatataaggt ttaccctaaa tagacactgg
     6061 tataacattg aaaaatatgg cttcctcgtg tatgattagg gtgtatttta aatagttgca
     6121 gaaagtaggt aaaagttttg agagttgcat acatacgtgt ctcatcgatc gatcaaaatg
     6181 aacaacgcca gattgaagaa atgaaaaaat tcggtgcaga gagaattttc atcgagaaac
     6241 aatctggcgc aacgattact catcgacctg ttttccaaga agcattagat tacgtccgag
     6301 atcaagatat ttttattgtg gaagctattg atcgacttgg aagaaattat gacgagatca
     6361 tcgcttcagt caattacttg aagaagaaaa atgtgaagct gatcattact agtttaccga
     6421 tcatggctga agcaattggc aatcctctcc tggataaatt cattaaggat ctgatcatcc
     6481 aaattttggc catgatcgct gaacaagaac ggactgaatc gaaacgtcgc caggcacaag
     6541 gaattaagat cgcaaaagca aacggcgtct acaaagggcg gcccaaatta tacagtgcag
     6601 acgcaaaaga tccccaacgt cgccttgttt acaaaagcat cgttgaagat cttaaaaatg
     6661 gtgttgcgat tgctaagatt gctaaagact acaatgttac gagacaaacc gtgtatagaa
     6721 taaaaaaaga cagcatggtc aatgacaaat agttgatcat gctgctttta ttatcttctc
     6781 atctttaatt tcctacatat aattactatc tataaaatta agtcttactc agaacagata
     6841 aagcataaaa ttccaacaaa ccatttttta cttaactaaa taaagagtct gttaatataa
     6901 tcttcactta tttacgttaa tcccctactg tatttgttgg ttccttatct atattttcta
     6961 caaaatcctt attatcttgt gatttagctt cgtataattc tttgtatgtc gacacattgg
     7021 ttatactaat tcctatagct agttcttgag actctacttt tctctctagc tcctttgaca
     7081 aagtgatttg agatttattt ggttccgttg gagtcaattc tatagattct tcataaaaat
     7141 ctctatacat aaagctat
//
LOCUS       DAPBBV010000081         6643 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.085, whole genome shotgun sequence.
ACCESSION   DAPBBV010000081 DAPBBV010000000
VERSION     DAPBBV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.085"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(1..859)
                     /locus_tag="RD486_002671"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="RD486_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="RD486_002672"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="RD486_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDT7664366.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="RD486_002673"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="RD486_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2603..3421)
                     /locus_tag="RD486_002674"
     CDS             complement(2603..3421)
                     /locus_tag="RD486_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7664367.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="RD486_002675"
     CDS             3582..4271
                     /locus_tag="RD486_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDT7664368.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="RD486_002676"
     CDS             4285..5787
                     /locus_tag="RD486_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7664369.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="RD486_002677"
     CDS             5800..6276
                     /locus_tag="RD486_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7664370.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="RD486_002678"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="RD486_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1033 c         1204 g         2234 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttctat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atg
//
LOCUS       DAPBBV010000082         6624 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.086, whole genome shotgun sequence.
ACCESSION   DAPBBV010000082 DAPBBV010000000
VERSION     DAPBBV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.086"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            70..153
                     /locus_tag="RD486_002679"
     CDS             70..153
                     /locus_tag="RD486_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HDT7664371.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            278..1015
                     /gene="erm(B)"
                     /locus_tag="RD486_002680"
     CDS             278..1015
                     /gene="erm(B)"
                     /locus_tag="RD486_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HDT7664372.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1185..1445
                     /locus_tag="RD486_002681"
                     /pseudo
     CDS             1185..1445
                     /locus_tag="RD486_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1608..2273
                     /locus_tag="RD486_002682"
                     /pseudo
     CDS             1608..2273
                     /locus_tag="RD486_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2309..2554
                     /locus_tag="RD486_002683"
     CDS             2309..2554
                     /locus_tag="RD486_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7664373.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2657..3526
                     /locus_tag="RD486_002684"
     CDS             2657..3526
                     /locus_tag="RD486_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDT7664374.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3507..4241
                     /locus_tag="RD486_002685"
     CDS             3507..4241
                     /locus_tag="RD486_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7664375.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4274..5182
                     /locus_tag="RD486_002686"
     CDS             4274..5182
                     /locus_tag="RD486_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HDT7664376.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5179..5721
                     /gene="sat4"
                     /locus_tag="RD486_002687"
     CDS             5179..5721
                     /gene="sat4"
                     /locus_tag="RD486_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HDT7664377.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5814..6608
                     /locus_tag="RD486_002688"
                     /note="aph(3')-IIIa"
     CDS             5814..6608
                     /locus_tag="RD486_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HDT7664378.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2321 a          996 c         1389 g         1918 t
ORIGIN      
        1 tttgtgtata ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag
       61 ggattcgtca tgttggtatt ccaaatgcgt aatgtagata aaacatctac tgttttgaaa
      121 cagactaaaa acagtgatta cgcagataaa taaatacgtt agattaattc ctaccagtga
      181 ctaatcttat gactttttaa acagataact aaaattacaa acaaatcgtt taacttctgt
      241 atttatttac agatgtaata acttcaggag tgattacatg aacaaaaata taaaatattc
      301 tcaaaacttt ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa
      361 agaaaccgat accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc
      421 taaaataagt aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc
      481 agaaaaatta aaactgaaca ttcgtgtcac tttaattcac caagatattc tacagtttca
      541 attccctaac aaacagaggt ataaaattgt tgggagtatt ccttaccatt taagcacaca
      601 aattattaaa aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga
      661 aggattctac aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca
      721 agtctcgatt cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt
      781 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
      841 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
      901 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta
      961 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
     1021 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
     1081 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
     1141 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
     1201 ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg
     1261 aatgtaagtt tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa
     1321 aagaattact ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc
     1381 cctacaatgc cgttgtaaaa attggggaaa agggatatat tgattttatc tctttttcaa
     1441 aataaacatg gggctgaccc aaaagtagct cctatatgaa aaatagaggt ctttccattt
     1501 agatagtagt ggaaagacct ctatttatct tttgaaagtg aatacaaaaa taaagcacac
     1561 tctgctataa tataggtgat taatccattt gagagaggtg ctttatcatg tatcaaaatt
     1621 ataccataaa ccaactttgt ttgcctatag atcttgaaat taaattagaa gaaaatgatt
     1681 ttgctcatgc cattgtgcag tttgttgact ctattcccga tgaagtcttt cttccttatt
     1741 atcaatctat gggtagaccc caatatcatc ctcgtatgct actttccatt attctttgtg
     1801 cctatattca aggggtttat tcgggccgcc aaatacaaaa tatgctgata gatagtattc
     1861 ggatgcgcta cttatctcaa gagcaattcc ctaactttcg tactattaat cgttttcgcg
     1921 ttcatccgat tatgaacgat attctagatc attcatttgt tcaatttcgt gagctactgg
     1981 ttcaaagtgg cttaatcagt ggcagtgctc tatacattga tggtacaaaa attgaagcgg
     2041 atgcgaataa atactctttc gtttggaaaa aaagtatttt aaagtataag gatagccttg
     2101 atcaaaaagc ccttgaaaac taccaacaaa tggtggaaac aaaaatctta cctgagttaa
     2161 tagatgattt aaaggatgaa ctttctatag aagagattga aaggattcgt caatctttgg
     2221 aagaaaagga aaatcaatta attgaagcga ttgaccaaac cgaaacagta gaagggggct
     2281 gacccattat taataaggag tggacaacat gattgatgta aatgagctat tggaagaagc
     2341 tattagagaa actgaaaatc taaatgatgg cgaagttttt cttgttaaag atttattcaa
     2401 gggatatgtg gggaatagga tacccagaaa ggatcgactt ctgcttggaa cgttattttt
     2461 aaaccatgtt agcaaaatga atggtaattt aaaggctatt gaaaagactt catctaatca
     2521 gcagaggtat aaaaagacaa ttgataagtt ttaactatct tttgtgaaat taaaaaaatt
     2581 ataaatatgt tgagtagaag caaaagattt ggcttggaat ttttacagca gtgaatcgat
     2641 aaaaggagca tgcttgatgg tagataatat tattaaatca gtagcagaga aattatcctc
     2701 tctgtcttat atagaaggta ttgttttagg tggttcacgt gcaaggggca cccatacaga
     2761 ggattcggat atagatatcg gcatctatta caattcagaa tcatttgaca taaatactat
     2821 taatcaattc gctacaaagc tggatgatga gcatagaaat aaccttgttg tacctcccgg
     2881 agcatggggt gattggatta atggcggcgg atggttagtc ataaacgggt atcatgtgga
     2941 tttaatttta cgtgatatta aacgtgtgga acaaataatg aaagatacag agcacggaat
     3001 tgttactgcc aattatcaga ctgggcatcc ccatggttat attagtgcaa tgtatcgagg
     3061 agaattagcg attagcaaaa tactatatgc taagaatgaa agcttatgcg aattaaaaaa
     3121 acaggcagaa acttatccca atgctttgca gaaaagttta gttaactttt ttatgtttga
     3181 agcagggttc tctttaatgt ttgtaaaagc aaattcggga acagacgata aatattatat
     3241 tgcgggtcat gtttttcgta tagtttcatg tttaaatcaa gtgttatttg catgtaataa
     3301 tgcttattgt atcaacgaaa agaaagctat aaaactgctt gaaacttttg aacataaacc
     3361 tgaaaaatat accgagaagg taaatcatat ttttgaagta ctcggtatct cactttttga
     3421 atgctacgac atgaccgaga agctttataa tgaagtgaat gaaattgtat cggagataaa
     3481 taacttttta aacgaggaga gttcagatga aagaaaacaa atatgatgat aatatatttt
     3541 ttcaaaaata cagtcaaatg agtcgctcgc agaaaggact ggctggtgcg ggagaatggg
     3601 agactttgaa aaagatgcta cctgatttta agggtaagcg tgtgcttgat ttaggatgcg
     3661 gctatggatg gcactgtata tatgcgatgg aaaacggtgc ttcctctgta gtaggtgttg
     3721 atatttctca taaaatgctc gaagtagcaa aaggaaaaac ccattttcca cagattgaat
     3781 atgaatgctg tgccatagaa gatgtggatt tcccagagga gagctttgat gtaatactaa
     3841 gttcgcttgc gtttcattat gtagcagact atgagaattt aataaaaaag atatatagga
     3901 tgctgaaggc tggtggcaat ttagttttta cagttgaaca tcctgttttt actgctcatg
     3961 gaacacaaga ctggtattat aacgaaaaag gagaaatact gcatttcccg gtggacaatt
     4021 attattatga gggcaaacgg acagctatgt ttttggaaga aaaggttaca aaatatcata
     4081 gaacactgac cacatatcta aatacactgc tttcaaatag ttttataata aatcagattg
     4141 tggagccaca gccgccagag aacatgatgg atattccggg gatggcggat gaaatgcgac
     4201 gcccaatgat gctgattgta tcggcaaaaa agaagatgta ataatataga aaaaataaac
     4261 gaggagtatg taaatgagat cagaaaaaga aatgatggat ttagtacttt ctttagcaga
     4321 acaggatgaa cgtattcgaa ttgtgaccct tgaggggtca cgcgcaaata ttaatatacc
     4381 taaagatgaa tttcaggatt atgatattac atattttgta agtgatatag aaccgtttat
     4441 atctaatgat gactggctta atcaatttgg gaatataata atgatgcaaa agccggagga
     4501 tatggaatta ttcccacctg aagaaaaggg attttcctat cttatgctat ttgatgatta
     4561 caataaaatt gatcttacct tattgccctt ggaagagtta gataattacc taaagggcga
     4621 taaattaata aaggttctaa ttgataaaga ttgtagaatt aaaagggaca tagttccgac
     4681 tgatatagat tatcatgtaa gaaagccaag cgcaagggag tatgatgatt gctgcaatga
     4741 attttggaat gtaacacctt atgttattaa aggattgtgc cgtaaggaaa ttttatttgc
     4801 tattgatcat tttaatcaga ttgttcgcca tgagctgctg agaatgatat catggaaggt
     4861 cggcatcgaa acaggcttta aattaagtgt aggcaagaac tataagttta ttgaaaggta
     4921 tatatccgag gatttgtggg agaaactttt gtccacctac cggatggatt cctatgaaaa
     4981 catatgggaa gcattatttc tatgccatca attgttcagg gcggtatccg gtgaggtggc
     5041 ggaaaggctt cattatgcct atccggagta tgataggaat ataacaaaat ataccaggga
     5101 catgtataaa aaatacactg gtaaaaccgg ctgcctggat agcacatatg ccgctgatat
     5161 agaagagagg cgggaacagt gattacagaa atgaaagcag ggcacctgaa agatatcgat
     5221 aaacccagcg aaccatttga ggtgataggt aagattatac cgaggtatga aaacgagaat
     5281 tggaccttta cagaattact ctatgaagcg ccatatttaa aaagctacca agacgaagag
     5341 gatgaagagg atgaggaggc agattgcctt gaatatattg acaatactga taagataata
     5401 tatctttact accaagacga taaatgcgtc ggaaaagtta aactgcgaaa aaattggaac
     5461 cggtacgctt atatagaaga tatcgccgta tgtaaggatt tcagggggca aggcataggc
     5521 agcgcgctta tcaatatatc tatagaatgg gcaaagcata aaaacttgca tggactaatg
     5581 cttgaaaccc aggacaataa ccttatagct tgtaaattct atcataattg tggtttcaaa
     5641 atcggctccg tcgatactat gttatacgcc aactttgaaa acaactttga aaaagctgtt
     5701 ttctggtatt taaggtttta gaatgcaagg aacagtgaat tggagttcgt cttgttataa
     5761 ttagcttctt ggggtatctt taaatactgt agaaaagagg aaggaaataa taaatggcta
     5821 aaatgagaat atcaccggaa ttgaaaaaac tgatcgaaaa ataccgctgc gtaaaagata
     5881 cggaaggaat gtctcctgct aaggtatata agctggtggg agaaaatgaa aacctatatt
     5941 taaaaatgac ggacagccgg tataaaggga ccacctatga tgtggaacgg gaaaaggaca
     6001 tgatgctatg gctggaagga aagctgcctg ttccaaaggt cctgcacttt gaacggcatg
     6061 atggctggag caatctgctc atgagtgagg ccgatggcgt cctttgctcg gaagagtatg
     6121 aagatgaaca aagccctgaa aagattatcg agctgtatgc ggagtgcatc aggctctttc
     6181 actccatcga catatcggat tgtccctata cgaatagctt agacagccgc ttagccgaat
     6241 tggattactt actgaataac gatctggccg atgtggattg cgaaaactgg gaagaagaca
     6301 ctccatttaa agatccgcgc gagctgtatg attttttaaa gacggaaaag cccgaagagg
     6361 aacttgtctt ttcccacggc gacctgggag acagcaacat ctttgtgaaa gatggcaaag
     6421 taagtggctt tattgatctt gggagaagcg gcagggcgga caagtggtat gacattgcct
     6481 tctgcgtccg gtcgatcagg gaggatatcg gggaagaaca gtatgtcgag ctattttttg
     6541 acttactggg gatcaagcct gattgggaga aaataaaata ttatatttta ctggatgaat
     6601 tgttttagta cctagattta gatg
//
LOCUS       DAPBBV010000083         6177 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.087, whole genome shotgun sequence.
ACCESSION   DAPBBV010000083 DAPBBV010000000
VERSION     DAPBBV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.087"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(440..610)
                     /locus_tag="RD486_002689"
     CDS             complement(440..610)
                     /locus_tag="RD486_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664379.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(625..1158)
                     /locus_tag="RD486_002690"
     CDS             complement(625..1158)
                     /locus_tag="RD486_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDT7664380.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(1179..2123)
                     /locus_tag="RD486_002691"
     CDS             complement(1179..2123)
                     /locus_tag="RD486_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HDT7664381.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            2760..2846
                     /locus_tag="RD486_002692"
     CDS             2760..2846
                     /locus_tag="RD486_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDT7664382.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(2967..3656)
                     /locus_tag="RD486_002693"
     CDS             complement(2967..3656)
                     /locus_tag="RD486_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664383.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(3663..3941)
                     /locus_tag="RD486_002694"
     CDS             complement(3663..3941)
                     /locus_tag="RD486_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664384.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(3901..4815)
                     /locus_tag="RD486_002695"
     CDS             complement(3901..4815)
                     /locus_tag="RD486_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDT7664385.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(4797..5177)
                     /locus_tag="RD486_002696"
     CDS             complement(4797..5177)
                     /locus_tag="RD486_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDT7664386.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(5627..5914)
                     /locus_tag="RD486_002697"
     CDS             complement(5627..5914)
                     /locus_tag="RD486_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7664387.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(5934..6158)
                     /locus_tag="RD486_002698"
     CDS             complement(5934..6158)
                     /locus_tag="RD486_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HDT7664388.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
BASE COUNT         1633 a         1153 c         1043 g         2348 t
ORIGIN      
        1 tcgttttttt aaaattgctt gttatattaa ataatcttag taattttatt atataacatt
       61 ttattatata acaatgatta acgtcataaa aagtagtttt gaattcataa tcgtttaaat
      121 aaaattataa gatcagttat ttaaacagct agtagacata atgtgtatac taccaagtaa
      181 cgcctgtacc aagggatcca ggcgctgatt ttgtgaattt ttattggtct aggttaaaag
      241 ctctttttaa ggcttggttt tctgcggttg tttctttcta attctttgtg aatattgatc
      301 ggtcattttt taaatacttg ttatttttgt ttgtgtttgt tatgcttttt acatatctca
      361 tattcattta ttattctttt ctaaggttaa taataggata atctctttca gaaagactgc
      421 tcgtacgagc agtcttttct tatttatcaa gtttttctac aaatacttcc tcattttgac
      481 tgttgtagta attaggattg agttttagtt cccctttttt atttcctttg ttggccactg
      541 ataataacat tgggctaaag cttaatattc ctagtaggat agaaccgaat agcaagtgtt
      601 tttttgtcat aagtatttcc ttcttcattt ccatagctgc caccattttt tccaattctt
      661 tgtttgttcg tccattgttt ctgttgcttc agaaagagtc gttgaactat tctctgaaga
      721 ctcttccgta taagtcaact gcagttgctc ctgaagtttt tcgatttgtt ggttggcttg
      781 cagggtgagt tgttgttgct ggtcgagtag tttttgtata tgagaattat tttgctcttt
      841 gagggcaagt tgttctcgta aaaattcatt ttcttcacgc aactgatcta gcaacttgtt
      901 tgcaaccacg tttttgtttg gtatataagc atttttatcg ttgttttgtt catgtttatg
      961 caacttatct agcaaccttt gattgtctaa gttgcgagca agttgcaata ctccagaacg
     1021 caatacaacc ttataaccac gctcattttt agctatcatg gaagaatcta atttttggat
     1081 atgtttcgat attgcttgcc tactcatctt aaaaagatct gacaattcct ttattgtaaa
     1141 ggtttcttgt ggttgcatac tggttgcctc ctaggttgct actggaataa attatctaaa
     1201 tcagataata aacttttttt ctctttttcc gaaagtgcgg actctgtttg tttttcaaga
     1261 gcttttttct ctttttctag ttgtttgatt tgttggagga gttcaagttc tcgtttcttc
     1321 tgtttgattt tttcgttaat tgttgtagcg ggttcttcgt attctttttg tttatcagct
     1381 aaagccaatg ctttattttg gtcttctttg gttggtgcat gtttgttaaa gtcgtctgct
     1441 tttttgatct caggtttgaa cgtaaattga tagccaataa caggttttcc ccgtcctttt
     1501 ccgtatttct ttttgattgt tagtcctttg aagattgcag ttagttcttg acgtataggt
     1561 tttataactc gtttatctat atcaggttgc ttataacttt taggaatatc taataattca
     1621 agaaagtctt ctttggagaa atatgcgaaa cctttggttc tgtattgctt taacagacga
     1681 aacatagtct ttgcatagcc actttgtagc tcgttgaatt gttgtaaaga atagcgtacc
     1741 cactcgtcta aattatttaa caaaggcagt gctttttcgt aaattcgtat atctacgtaa
     1801 ggattttcta cgtccccgtt gattttaaat tctgtaaaca ttacaaacat atcgtaagaa
     1861 agcccagact cacttctacg accaaagcgt aaagataaga ttttttcata agttgctttt
     1921 aaatcttcta caaatcgtac atttgcagtt gctttgtagt tacttaaatc ttttagttgg
     1981 tcaaacgtaa aacgaactgt cttatcccct ttttcacgca ttctagacac gatggaaaaa
     2041 aacaaattca tttcaaccgg tgtaaatttt cttaaaggaa ttgtatttaa ttcatggtgg
     2101 tattttacaa tctcattagc catataatca cctcaatcca attatgaatg acatttttta
     2161 aatgtcaaga cattcatatt tgacgttcaa acagacaaaa tgtccttcat aaacagacaa
     2221 aatgtccttc ataaacagac aaaatgtcct tcataaacag acaaaatgtc cttcataaca
     2281 ttctgtatcc attggtagag taaggacaca gcttacggta aagaggttta aaaagaggtt
     2341 taaaaagaga tataaaaaga ggggggctaa ttttcccgcc taaaaaccac ttcttttttc
     2401 tttaaacagg ttcgcgcatt tttcaaaact gccaatccaa aaccttgctt cctacggtcg
     2461 ccaaaaaggt gtgatcgcta cgctctcaca ttgtactgcg cagtcgccta aaggctcctt
     2521 tgctaaaaac atgttggtaa agaggccttt gagcggttct gaatgcttat ctaagccgtt
     2581 ttaagacagt cttggataaa aatccttatc tagctttaaa gcgccttaca ggcggtcagg
     2641 gcaagcccta acaaccctaa aataagcgat acttaaaaac accacacaag tttaattttt
     2701 taagatataa taacttgtcg cctatccgac agtcttgcga ctggaaggag gtgtatctaa
     2761 tgtttgaatt gttcatttgc ccccttctta tagaagtttg tgtctcttta ttcagttatt
     2821 ggttgaataa ccgaaacaag aagtaaaatc aataaaggcg acatcaacct gaaaaaaagc
     2881 cccagagaat ccgacctctc tggggctttc gtgtatctaa tgtttgatca tttgcatgtt
     2941 tagtttaaca tgattgccga tcaaattcaa ttttgctgtt gctgatctaa ccattccttg
     3001 acacttttta gataatttaa tgccgtttct tttttcgttg gattttgtat gttcgttgct
     3061 tgctgaagca gtgctttata acgttcgtag gtaactgatt gttgccgttc ttttcgttcc
     3121 tgttcactag ttgaaaaagg gattgtatca ctgaataaat tataacaagc ttcttctgtc
     3181 tgcgtatctt taaaatattg cacgtctttt ttggttcgct catagttgtc ttgaacctct
     3241 ttttgctgtt tttctggcaa gttttgataa agacgagtga gtttttccat gtttttatcc
     3301 gtcaaacgtt tttcttgatt cacaaaaata tcgttcattt cctcataaca agtggtaaac
     3361 tcttccattt tttgtgttaa cacttgctcc tttttctttt tatcacatgc tgcttcatac
     3421 ttttgagtga tatcccctaa taaaatactt cttgaaatac gtttatttcc ctctaaaacg
     3481 ccgaataaac cacttaaaac gattgataat gtaaatataa cccctggcaa caaaaacctc
     3541 ttaaatcgaa ttttagagcc ttttaatgaa tatcttgttt gataagcctt atagctaagc
     3601 caaataattc ctaaaatact ggcaaaaatg agtagatagg gtaaatagaa tgccatttct
     3661 atttattctc cccataccag ccaaaaggct aacagtgtca tgattaagca acataagggg
     3721 gcaagaatat ccattgatcg ctgcataatt acttttttct gttctttatt tcgctggttt
     3781 aatagcgcat ggtggaattt tttgacttgt gaatcaattg tagtttgtat tctttctttg
     3841 gtataaggtg caagaaaagc acgttgtttc tttatttcat tttctatgtc ttgtaacgtt
     3901 ttagaacgat aattcttgtt ggtagtctgc tcctctttca acgtgttggt catggtttct
     3961 tcgagtcggt ctaatttccg gttgttcagt cgtaagagtt cgttgttctc ttcgtacttc
     4021 ttttgcagtt tcgcgaatgc tagctcgagc tcttcgtagc tcgttggttc gttgttgatt
     4081 gtaggctcgt tctcgtctgt ccagctcatg taaaatcgtc tccttttcgt aatcctttcc
     4141 tagtttgttg gatcgtactt ttttcttttt gtggatcaat tcgtaagtaa aatttttccc
     4201 acgattcaag caatgaatgc cgaatgtttt aagagaatca caaaattggt tatacgttcg
     4261 agtttttttg tttttcattg tttgatcaat cgcaaaccga atttcgtctt tccaaacagg
     4321 ttcatttttt tcttttaatt tgatttcaga catggttcgt ttttcgggtt tcttccctcg
     4381 ttcagtgatt gttaagtcat gttcaagaca aatctcgtca tttaggtcat aacatttgtt
     4441 taaaaatgct tgaccatggg cttgaaattt gttcccagtt tccagattga cggagttaat
     4501 gacaatgtgg ttatgaatat ggtctttgtc tgtatgtgtg taaatcgcga tttggtggtc
     4561 aggggctatt tttttcgcat actctgcccc tagttgattg gctttttcag cggtaatttc
     4621 tcctggtcga aaagactgga tcaataagtg tgcttgtaca cgatcgtctt ttccatacag
     4681 catgcgaatt tgtttcattt cgcttttggc ataatcaatg tcacagttta tccctgtttt
     4741 gacggttgct cgtggttcgg cgtaattgat cgctcggcta caagaagtgg ttcggcttac
     4801 tttaactgtt gccatatctt ttgtagctcc ttttgcatga tttttaggtt ttcggataag
     4861 cgttgggcgt cgccaggatc aacgtcgtgt tggtgtgtgt tgcaccactt ggcaatttga
     4921 ttgatattcc cgccagcttt ggctaaatcg cgcgcgattg cctgagcaat gtctggcgcc
     4981 actttcggtg tcaccagacg cgcgttttgt gccttggctt tcacgaaagc cggcacactc
     5041 atttgcaaag cttcagctga ctgcttcagc tttgcaaatt cggattcgct cactcgaaaa
     5101 ctgatttgtt ttggctcgga tcgataggta tattttttag aatgattgct agccaaatat
     5161 tgattttgtt cgctcataag tcccaccctt tcagtacgtc ctacggacgt atcgttcgca
     5221 ataccattgt acctaaaaag gtacaataag taaagctcac taaagctcac taaagggctt
     5281 ggcaagctct atatttgcta gccaaatacc tacgtatttg gtgcaaataa ccgcttgtca
     5341 aaggggcgca agctccccct tgaatccccc tcccccccac tctccacaat acaaaaaaga
     5401 ctagcaaatg ctagccactt tttgtaaagt ttcgcttgtt tcaccttcgg tgaaattgtt
     5461 gcaaatcaat aattaggtag agctacattt ttttcgttgt tcaaagattc ttatgccatt
     5521 tactattaat aaatctataa atatgataat ttttcggctc tataatttat gggactgatg
     5581 aatcagaatt gattcttcag tcccattttc attttattcc aaagaattaa ctccaaatac
     5641 caatagaagc ccatcctcta tatacttgag attccttact aacaatttct tgtaattcta
     5701 ttaaagattt aggtaatcca aatttatgtt ttaaaatata tcttccaaga aaactactta
     5761 atttcatact aacttcacca acactttttc cctcactgat ttctttagaa taaagaaaga
     5821 gcttttcttt taagtcagga tagtcatcta tagttgcttc attgtatact ttactaattg
     5881 catttaaaag tttttcttct ttagtaaaat ccattataat aacctcccta ccactacctt
     5941 ctaggtgccc atggaccatg attaacccaa ccattaacaa taatttttcc aatttctcct
     6001 ttagcttgat tccaatctac ccaacatttt tctttgttac aataaagacc atttccatag
     6061 taagtagctg catcaacttt tattcctgta ccgatgccag ctagacaagt tcctaatatt
     6121 cctagaataa cacaatgttt taatactttc tttttcatga ttgtttttcc ttttcgt
//
LOCUS       DAPBBV010000084         6144 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.088, whole genome shotgun sequence.
ACCESSION   DAPBBV010000084 DAPBBV010000000
VERSION     DAPBBV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.088"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(258..1763)
                     /locus_tag="RD486_002699"
     CDS             complement(258..1763)
                     /locus_tag="RD486_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7664389.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1760..2446)
                     /locus_tag="RD486_002700"
     CDS             complement(1760..2446)
                     /locus_tag="RD486_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7664390.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2639..4060)
                     /gene="gndA"
                     /locus_tag="RD486_002701"
     CDS             complement(2639..4060)
                     /gene="gndA"
                     /locus_tag="RD486_002701"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDT7664391.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            complement(4230..4409)
                     /gene="rpmF"
                     /locus_tag="RD486_002702"
     CDS             complement(4230..4409)
                     /gene="rpmF"
                     /locus_tag="RD486_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDT7664392.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(4467..5036)
                     /locus_tag="RD486_002703"
     CDS             complement(4467..5036)
                     /locus_tag="RD486_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDT7664393.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            5222..6124
                     /locus_tag="RD486_002704"
     CDS             5222..6124
                     /locus_tag="RD486_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7664394.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
BASE COUNT         1747 a         1290 c         1032 g         2075 t
ORIGIN      
        1 aaataataat atagcaatct ctttataaaa ttgcaataga aaattcccta tttttattta
       61 ttatttttaa acacgaatat tacagcattt tattgttttt tcgttcatct aaaagatact
      121 tacatttaat taacggatgt tattctattt aattgttcgc tagttttttt ataatgacat
      181 ccctgaattt ctcacttgct tgtattttgt accttattct ttgttggata tataaaaaaa
      241 caagtaaagc acatgcttta cttgtcttct gcctttgcga taggaataaa gattctaaaa
      301 attgtccctt gccctactac actttctgct aagatacgtc ctttatagtt ttcaaccagt
      361 tgtttagcga tagacaaccc cagaccattt ccacccttcg ttctagctct tgctttatcc
      421 actcgataaa aacgattgaa gatcttatta aggtcttctt tgggtattcc ttcgccaaag
      481 tcctgaatcg cgatctcaaa ttcattcaga gtggaagaaa tagagatatg gacttctttt
      541 cgtgtagttg aatactttac tgcgttatcc aatatgataa tgattaattg ttcaaagtga
      601 ttacgataaa tttgcagggt cacttctttt gtcaaatcat catctaaagt gatcacatag
      661 tctggatata atatcttgaa attattataa acttgatagg tgacttcttt tcctttagtt
      721 gtttcattcg cataatgaac atctacttgt tctgctcttg ataagtctag catctcttga
      781 actaagcttt tcatacggct gatttcttgc atgctggcgc ttaatgattc ttctaatatc
      841 tcaggatcat ctttccccca acgatttagc agactaagat gcccttcaat aattgcaaca
      901 ggtgtcctta actcatgaga tacgtcttcc acgaattgct cttgttgttc aatatacaaa
      961 cgcatacggt caagcatctc attgaatatt tcagctaaat ctgccaattc atcatttgtg
     1021 tcgatttcag gcatgtggat atctgattgc ggatctttac gtatagtatc cattgtatct
     1081 ctgagtacct tgagtggttt taagaaataa gaagataaaa agaaacctaa aatactactt
     1141 aagatcaaag aaacaacttc taaaacaata agagtcaata atagcttatt tcgaatatca
     1201 tagaaagaag ataattcata gaagctttgc gcatagccga tcttttctct tgtaccttta
     1261 gaatatatag gctggataga taaaaagcca gtttttcctt ctagtgtaac gatcgttgga
     1321 actttacgtg tagtctgaat caggtttcga ctgttttcat gggttttaaa aatcaagttc
     1381 tcgtccaaat cataaacata aagatccatt gatggctgcc ctagctcagc tataaaggaa
     1441 tcgatcttca ttaagtttcc ttcgaccagt gaagtatgat ctacgacctc atctccgtca
     1501 tttgtcgctt tcgtcagatt acgatacgta tttactaatg tcagttcttc atccgagtta
     1561 gccaaacgag aagctacttc tgaaatcgta cgctctacat tgtttctttc ttttgccaca
     1621 atcagattga tagatgattt ataggtaatg acagcgaaaa ttgtaaacac aacgaatatg
     1681 aagaaagaac tcgcaaaggc ccacttgatt gtcaaggagg gccctttcag ttctcttttt
     1741 tccgattttt tcggctttat cacgagcgca tcacataacc tgttccgcgt acagtttgga
     1801 tatagctttc ctccccggga acgtcaattt tgttgcgaag ataacgaata tatacgtcca
     1861 ctacgtttgt ttcaacttct gtttcgtatc cccacacttt atttagtaaa acgtcacgtg
     1921 ctaataccac gttcacgttt tccattaaag taagcagcaa ctcgtattct ctttttgtta
     1981 gttcaattac ttcatttccg cgacgtacga cacggttttc tttttcgata gtcaaatcgc
     2041 gataagtaat agtagtttgt ttagccacat ttttatcgcc ttcaatatcg attcgacgca
     2101 acaatgcacg aagacgtgct aataattctt cgatagcaaa tggtttgacg atgtagtcat
     2161 ctgctccgtg gtcaagtcca gatacacgat cgatcacaga atctcttgca gtcatcataa
     2221 tgattggtgt atttttgact tggcgtacac gtctgcagac ttctaaaccg ttcaattctg
     2281 ggagcatcag atccaacaat atggcatccc actcattatt taatgccgca tctaaaccag
     2341 ttcggccgtt gtagtggact tctgcgttat acccttcatg cttcaactct agctcgacaa
     2401 atcgtgccaa gttcttttca tcttcaatga ttagaatatt gctcatttat tattttatcc
     2461 tttctattct actggctttt taaaaactct atcattatac cgataatatg cttaaaaatc
     2521 tatagtcatt ttattatgga tagcaatttt aaaaaagagc tgaagtctac tcataacaat
     2581 cgacttcagc tctttcgtcc tctttttatt ttctcatttc ctaacagccg aaagactatt
     2641 attcttcatg gtaccatgag taatggaaga ttccttcttt gtcgacacgc tcataggtat
     2701 gtgcgccaaa gtaatcgcgt tgggcttgga ttatatttgc aggcagacgt tctgctctgt
     2761 atgaatcgaa gtaagcgatg gctgatgaga aagtcggtac aggtacgcca gcttggacag
     2821 ccaaggcaac gacgtctctg actgattgct gatatttttt cgtgatttca acgaagtaat
     2881 catctagcaa taaattttcg atctcaggat ttttgtcata ggcatccgta attttttgca
     2941 agaatcgagc tcggatgata catccagcgc gccagatttt tgcgatttca ccaaatggca
     3001 agtcccaatc aaattctttt gaagcgacac gtaattgagc aaatccttgg gcataactca
     3061 tgattttact gaaatacaac gcttctcgga ttttttcgac caattctttt ttgtctcccg
     3121 tgaactcaaa atcgttcgta cgagacaaaa tcttgcttgc ttgtacgcgt tcttctttat
     3181 aagcagaaat atagcgggca aatacagatt cagtgatcaa tggaagtggc acacctaagt
     3241 caagcgcgct ttggcttgtc catttacctg ttcctttatt cccagctgca tcaaggatca
     3301 catctactac tggtttacct gttccttcat cgtctttacg tgtcagaatg tcagcagtga
     3361 tttctatcaa atagctgtct aattcgcctt gattccattc tttaaagata tcagccattt
     3421 cttctactga aaggtttaaa atattcttca ttaagtcata agattcagca atcagttgca
     3481 tatctccata ctcaataccg ttgtgtacca ttttcacata atgtccggct ccatttgggc
     3541 caatatatgt gacacatggt gctccgtctt ctgcttttgc agaaatttgc tctaagattg
     3601 gtgcaactag cgcataggct tctttttgtc caccaggcat gattgaaggt ccttttaaag
     3661 ctccttcttc accaccggaa acgcctgtac cgataaagtt gatgccagag ttggctaact
     3721 cttcattacg acgcatcgta tctttaaaga atgtatttcc tccgtcaatc aaaatatcgc
     3781 ctttatcaag gtgaggaagt aactcttgga ttgttgcatc tgttgccggt cctgctttga
     3841 ccattagcaa gatccgacgt ggtttctcga tagattctac aaattcttcg attgtatatg
     3901 ttgctttgaa atttttatct gggtgttctt ctactacagc ggttgtttta gcccctgtac
     3961 gattgaataa agccactgaa tagccgcggc tttctatgtt caaggctaga tttttaccca
     4021 taacggccat accgacaacg ccgatttgtt gttttgacat atgaactcct cctacatacg
     4081 ggatttctcc ctaatctctt acattatagc ttaacacggc tacattgcaa actaaagaac
     4141 aacatatttt ttatttaccg actacaaaaa aataaacctc aaggctccat ggttagcctt
     4201 gaggttttac attttctaat taaaatgtat taagcttctt ttgacattac gtccttacca
     4261 tcatagtaac cacaatttgc acatacgtga tggctttttt tcatttcacc acagtttgga
     4321 cattcgttta accctttgat tgtcaatttg tagtgtgtac gacgttttgc ttttttagct
     4381 tttgatgttc ttctagctgg tactgccatt ttgctacacc tccttgtaaa gtcttgtatc
     4441 taaattagac acaatatatt ccaatcttac ttgttatcgt cgtcttttga tttagaatca
     4501 aaaagttcag atagttttgc aagacgagga tcaattttat tctcggcttc ttccattttt
     4561 ctgcgctggt attcttcttc ggaaacaact tcccaatcat tgccttttgg aagttctgtt
     4621 gctgcttcct cttcttttgt caatacccgc attggaatcg ccaataagat gttgtcttca
     4681 atcgactctg ctaaattcaa taatggacct tcaattagca aaatctcatc tgcagacatt
     4741 tgttcatctc tactttggaa ttgttcttct gtcatgaata cttcgtctac agaaaaatcc
     4801 atgggcagtt caacaggttc tagtgaacgt gttgaaggaa ctgtcaaagt cgtctgcaca
     4861 gtgtaatgaa cgatatagcc tttcttatca actgagacca aaccttcgac ttccactggc
     4921 gcaacatcaa gtattaaatt gtctcgcttc atgagagcgg ctttcaagtc gagcgtctca
     4981 tgaaaagtta acggtgtctc ctggtatttt ctcaattcca ataaagacca tttcattttt
     5041 catcactcct aagcaacaaa agcaattata cagggcaaaa agcatgttgt caatgaaatt
     5101 ttcttgacac cttgcagttc ataaaaaaac agaaaaatct ttattagaaa gcctctgttt
     5161 gctatcatcc tcagaatcat ttacaataat cattattcca ttaaaggagc ggatgatctt
     5221 catgaacacg aaagatatcg aatactatgt ccaaatcgtc aaacaaaaaa attttacgaa
     5281 agtggctaat tatttccgtg tgagccaacc tactattaca tatgcattac aacgtcttga
     5341 aaaagagttt gacaccgtac ttattacaag agatcgatcg catcacgaat tgatcgtcac
     5401 gccttctgga aagcagctgt ttctccatgc acaaaccatt ctccaagaga tttctactgc
     5461 aagagctgaa atcactcagt tgcaaaagaa aaagcttcgt tttggcatgc ctcctattat
     5521 cggcaatgaa tactttccta aactgtcaag ttactttatc aagcatgaat tgatgaatca
     5581 aattgagatt accgatggag gctctcggga cttatacggg atgatccgac aagggaggat
     5641 cgatttagct gtattaggct caacacagcc aatcgtggat caatatttag aaacagagtt
     5701 acttttggac aaacgtttca tgatcgtcgt gccacctaca catcctcttt ccaagcagga
     5761 tactgtctct ttcaaagata tagcagatga acagtttgta ctattgaacg aacattatgt
     5821 ccaccccgca gcattcacta agctttctaa acaaacacat actcatccaa aagttgttta
     5881 tcaaagcaat gacttgacga ttttaaagag tatggtccga gaaaatgtgg gtatcggttt
     5941 tttggcagag attgctgtcc atcctgaaga tcatttagtt tgcctccctc tttcagatga
     6001 agttcagcct cgcttcttga tttcattggc aaaacgaaca cagcagatcg tcacgcctct
     6061 tcaagaacaa gtagtccaag ttatccatga attcgttaca gcacaaaaaa acagctcttc
     6121 gtaaaagaag agctgttttt attt
//
LOCUS       DAPBBV010000085         6128 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.089, whole genome shotgun sequence.
ACCESSION   DAPBBV010000085 DAPBBV010000000
VERSION     DAPBBV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.089"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            196..921
                     /locus_tag="RD486_002705"
     CDS             196..921
                     /locus_tag="RD486_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664395.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="RD486_002706"
     CDS             911..1420
                     /locus_tag="RD486_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664396.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="RD486_002707"
     CDS             complement(1490..2938)
                     /locus_tag="RD486_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7664397.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="RD486_002708"
     CDS             complement(2938..3654)
                     /locus_tag="RD486_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7664398.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="RD486_002709"
     CDS             complement(3635..3985)
                     /locus_tag="RD486_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDT7664399.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="RD486_002710"
     CDS             4129..4902
                     /locus_tag="RD486_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7664400.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="RD486_002711"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="RD486_002711"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(5744..>6128)
                     /locus_tag="RD486_002712"
     CDS             complement(5744..>6128)
                     /locus_tag="RD486_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7664401.1"
                     /translation="LKPEGRKAVDIENSINEWLQSVLKNLFKSITFDCGKEFSNWKSI
                     SNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMDFHQVNQGFISSVASKRNHI
                     PRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT         1775 a         1189 c         1070 g         2094 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt ttttttaatt attatttgtc aaattaagcg agacaaaact
     5761 ttccatttac gtaactcaaa aaaacttcta atggtgtttg gtaatttagt gattttctag
     5821 ggatatggtt tcttttggac gcaacggatg agatgaatcc ttgattgact tggtggaagt
     5881 ccatttcttt tggtagtcca tcttttcgga ggagtccgtt tgaatgttca tttaatcccc
     5941 gttgggaagg cgttcctggg tctgcgaaat aaatatcaat atcattcgta ttactaatac
     6001 ttttccaatt agagaattct tttccacaat caaaggtaat tgatttgaaa agatttttga
     6061 gtacggattg aagccattca ttaatcgaat tttcaatatc aactgcctta cggccttctg
     6121 gtttcaag
//
LOCUS       DAPBBV010000086         6068 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.090, whole genome shotgun sequence.
ACCESSION   DAPBBV010000086 DAPBBV010000000
VERSION     DAPBBV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.090"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            832..1566
                     /locus_tag="RD486_002713"
     CDS             832..1566
                     /locus_tag="RD486_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7664402.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="RD486_002714"
     CDS             1582..2751
                     /locus_tag="RD486_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7664403.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="RD486_002715"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="RD486_002715"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDT7664404.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="RD486_002716"
     CDS             3841..4767
                     /locus_tag="RD486_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDT7664405.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="RD486_002717"
     CDS             4786..6036
                     /locus_tag="RD486_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7664406.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2027 a          997 c         1246 g         1798 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacaa caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agttaagt
//
LOCUS       DAPBBV010000087         5897 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.091, whole genome shotgun sequence.
ACCESSION   DAPBBV010000087 DAPBBV010000000
VERSION     DAPBBV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.091"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(976..1149)
                     /locus_tag="RD486_002718"
     CDS             complement(976..1149)
                     /locus_tag="RD486_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664407.1"
                     /translation="MSMLVRKLPLSVREFLFYLVCLIASGFKLIEHIFIFAYVLAMIA
                     FLSGGWLIIYLLS"
     gene            complement(1152..1550)
                     /locus_tag="RD486_002719"
     CDS             complement(1152..1550)
                     /locus_tag="RD486_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664408.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1766..2821
                     /locus_tag="RD486_002720"
     CDS             1766..2821
                     /locus_tag="RD486_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HDT7664409.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2841..3194
                     /locus_tag="RD486_002721"
     CDS             2841..3194
                     /locus_tag="RD486_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664410.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQAHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3376..3672)
                     /locus_tag="RD486_002722"
     CDS             complement(3376..3672)
                     /locus_tag="RD486_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664411.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3676..4494)
                     /locus_tag="RD486_002723"
     CDS             complement(3676..4494)
                     /locus_tag="RD486_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7664412.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4720..4941
                     /locus_tag="RD486_002724"
     CDS             4720..4941
                     /locus_tag="RD486_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HDT7664413.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            4943..5209
                     /locus_tag="RD486_002725"
     CDS             4943..5209
                     /locus_tag="RD486_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7664414.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5322..5861
                     /locus_tag="RD486_002726"
     CDS             5322..5861
                     /locus_tag="RD486_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664415.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVGTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKLQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVT"
BASE COUNT         2064 a          983 c          874 g         1976 t
ORIGIN      
        1 acttttgttt cgtgttaagt ttctttacat tcctacgcac ctcgagtgta aaatttcttt
       61 attcctccca cgctccatgt tattttatat ttcctttttc atgttatttt tatccagaaa
      121 ccgatcaagt ttttacctat tcccaaaatc catttattcg ttattttttt cactgattaa
      181 gaataattat ttgatgctta aattagctaa aaaagcgatt tgttactgat ataatcatga
      241 tattgcagct gaattaggcg gaaagataaa atgttcgcaa aatcaaagta tcaattatct
      301 tgttttttta taaatttgta agtaaaaatc taaaaaagtt ttcttttaat tggtatatgt
      361 attaaaatca catttaatca cccataaagt atgcgctttc atttttttgg atgagattaa
      421 tatcaataaa taacgatgta aaaatcattt attatgctct tttataagga tattaattga
      481 tctaatttga aaaaaatcaa aatttaaatg ttttaatatt acaaataaaa tcatgttatt
      541 gtaaaatggt ataaaaaagc taaatattct atttttgtta ttttattagc aggaaaattt
      601 aaatagtttt acaagaatcc gtagaaatat attggttttg ccttcagatt aatactggat
      661 catattaatc tgaatataat atatgaacta ataaatagct taacctcgct attttgtttt
      721 ttctgatcac tatctataca gcattagtaa atagaatttt aaaaataaaa aaattaagac
      781 aaaaaagtat caacataaac atatacatat acacgtttat gttgattcac ttaatttgtc
      841 ctttaaaaag cacttatttt aatataatgt tattttataa tcttattaca agctgattgt
      901 taggcgttgt cctttcatta catttattaa cggttatttt attgtttaat ttattaatta
      961 tttttgatct aaaacttagc ttaacaaata aataattaac caaccgccag ataaaaatgc
     1021 gatcattgct aatacataag caaagataaa aatatgttcg atcagcttaa accctgatgc
     1081 gattaagcag accaagtaaa atagaaattc tcttacagat aatggtaatt ttctaactag
     1141 catactcata attaacaccc caaagtaata ttgtattttg aacattttac atccaataca
     1201 gcatcaatca accattgcca atcaaaaata caaggcttca ttgaagtatg tttttcagat
     1261 gaaaagatat aatataattt cttcggaata atattttcag ttgttgggat caagctaaat
     1321 ctaataccgt ctaactcata gctaccagct ttctctccat taaaaatttc cttagcactt
     1381 tcttctaaag aatcaaaata tttttcgaca gcaatctttg aagcttttac tattgaagca
     1441 tttccctttt cgataaaatc tgcttttgtt ttaccgacaa taagtaattc ttgatcagta
     1501 aaatcttcta aaataatggt agtgtaattc ttatttcttc tcaatcgcat caggatcact
     1561 ccttaatata atttatgttt ttataatatc atactaagat aaatttgcaa gcatttattt
     1621 acaccttttt atttacactt tattataatt aattagactt ttatgattgc atttttttct
     1681 tataaacagt tgcaactaat agtaaatagg tgtaaactat tttcgtaccg aaataccata
     1741 aacacaaaca gaaagaggtc ataccatgaa agaaccatta ttgttttccg ttgacttagg
     1801 gaataaatca gtaaaagaaa tgagtacaca cgtttctcca ctctcacttc cctctcgtat
     1861 tttgaacaaa aatatcatta attcaggacg tttttctaat ataggttcct cattaaaacg
     1921 atcactaaac gtttctgaat atagcctagt aaacactact gaaagctatt actttgggaa
     1981 ggatatacac gagctaggaa aagatgacta cgtgatagaa tcactaggtt ttgggatcag
     2041 cagatacaag caggaaacct accaaaatat cctatctttc tctttagcta acctagcacg
     2101 tttagaagat caatctgatg acgttttaac cgctaatcta gttttaggtc tgccttcatc
     2161 cgactatacc gaaacaatcg tcaaatacgt gatgcaacaa gccacacgac aacattcagt
     2221 tgaagttgac ggtaaagctt ataatataaa cgtagatacc gtttgggtac tgccacagcc
     2281 gattggaaca ctatataacc tcctacttgc tgatgatggt agtgtacaag atgaaacatt
     2341 gatcagtcag aagatcggtt ttgttgatat tggtggtggc acgaaacttt ttgatgttgt
     2401 ccaaaatttt gaaattgacg aaaacaaccg tgaacaaaag gataccggta tttttacttt
     2461 atataatcgt atcgtaaata tgcttgacct tccgatcagt cctaatgctt tccaacttga
     2521 aaagattatc cgagaaggca aagaaaaagg cgtatatcta tttaaaccaa gcggaaatga
     2581 aagttttgat atttcagaag tagttgaaag agaaataaaa acatacacca atatggttgt
     2641 tgcagaagtt ttagctacat tcaaaaactt cacaacctta gataaagttg tctttactgg
     2701 tggtggggct tctattatcg acaaacaact tgtaaaagat aaaattccgc ataccttgtt
     2761 tgttgaagac agtgaatttt ctaatgtaaa aggcttttac aagtttggtt taactcaata
     2821 aaacagcgaa ggagatcaac atgaataagg gaaaatcaga gcgttatgta gttataatca
     2881 atagagaaaa ggttagcgag ttacctttag cagagtttct tgaatctgaa tatgaaacac
     2941 taggcgttaa atactctcag acgatcaaaa aagctttgaa tctatatcgg cgtgtaaaga
     3001 acaatgaagt tacaattatt gaagcaggca acgatagaaa cgatagcaaa gtagctgaag
     3061 taaagaataa accaactgat cataacccta ttcaacaagc gcatccttca acggttacat
     3121 ccgatcattc agcaaagaaa gaaaagccaa tgctaaaagg gttcaatgca ccaagtaaca
     3181 aagacttact ttaaaaataa aaaggcgagg ttacaatacc tagccttttt attatgtaca
     3241 aatacaaaca taaacatata cgtatacatg tatataaaca tgtatacgta tatatccata
     3301 aacacgtata cgaaatttag ttaagctata cctaaccgct tattccaata aaaaaagtga
     3361 tcagctttaa actgatcact caccaaaaac ttcatcatac aagttatcta tcatttcacc
     3421 aagtaaagct gaatctgatc gaattcctaa cttttcgctg attttagata gtttctttct
     3481 ttgtgatggt tgaagcgtga attgataatt tttcttcttt tcagaactat cactttttag
     3541 tttagctacc aaagaacttg ttgtttcttt aggtgtttgt ttaggttctt caactgcttc
     3601 aaccacttca ggaacttctt ctacttcagc ttcagcgaat tttttaaatc tattttcttt
     3661 cacttcaatc actccttatt cttgtgccgt atcaattatt ttgttgtata gcgtaaacgt
     3721 gctttcaaag aaatccttat tcttacgata gatattctta tccttagcga actcagcaat
     3781 attcttacct tctaagctag ttgcattaag caattccttc tcttgtacat atccaagata
     3841 attagataac gttggtacca attctaggaa ctcacgactt gaattagtat tatgtttgat
     3901 cctgctaccg atcgtagcgt atttagtttc catcagtgtt tcaccagtct taatatcaat
     3961 caactgtttt gctagtgcat caatatcttt accaagctta agcaaagctt caaaaccatc
     4021 tttagatgga tcagaaatgc ctacgacaag atcagataca gcccaagcat tttgagctag
     4081 tagacctgca tcattatgag tatcaatcag aattagatca tacttctctt taagctgttc
     4141 atagttaaca acgatccatc taaacagtag ggttctgttg ttaggcatat cacgcatttg
     4201 catctcaact tgttttaaat cttcacctgc tactaaaata tccatgttct catttatagc
     4261 taaaggttca gctgatccat gaagatataa atgattgatt gtattctctc ttttcgcttt
     4321 actgaaagca tcaggaaatc gttttgatag gttttgcgac ttatcttcat caatatacag
     4381 caccttcata cctaaatttt cgacagcata tccacctaga ttgtagattg ttgttgtttt
     4441 acctgttcca cctttttcaa tgtttccagt aatgattgac aacttctttt ccatgattaa
     4501 acctccctta ttaatctttt gtaactccat tatacactat aaacacgttt atgtatatat
     4561 ttatatacat aaacgtgttt atatttatat ttgcttttat attctacaac ataaacatat
     4621 atatgtatat gtttatgttt atgtatatat tcaaatatat aactattgca tttgtcatac
     4681 aatcgtagta caatgtaatt gaaaaggagt tgataaacta tgccagtaat aagtattcgt
     4741 gtatctaaag aagaaaaaga ttttcttgaa aaagttgctg aattcaacgg agataacatt
     4801 tctgaattta tgcgtagtaa ttccctgcaa acagcagaaa cgttagtaga ctttgccacc
     4861 tacaagcaac taatgaaaga gcatgaggaa aacgatcaaa gtatttccca cgaagatatg
     4921 ctaaaagagt taggcttata agatgactta ccaagtaaga tatgaacgtg aagctcaaaa
     4981 agcgctaaaa aaaatggata agtttcaggc aaaggttatc ctaaactgga tcgagaaaaa
     5041 tcttgtaggc actgatgatc caagaaagca tggtaaaggt ctaacagcta ataaatcagg
     5101 ctactggcga tatagggtag gtgcataccg tataatagct gatattagcg agcatgaagt
     5161 gacaattctt atattgtcta ttggtcacag aagtgaagtt tataagtaac agacaagctg
     5221 ataaggcttg tctgtttttt tgttaaccca acaaaatcac tgtttacgat cccactttac
     5281 ctaaaaaaga acaatatcct cttgatatta tacacaccag tgtgtataat ataagtgtaa
     5341 acaagctaat taactttcaa aaggagcgat tttttatggg atggtatggt gattattcat
     5401 cagcaaatga agtgatcgaa gaaaagaaag ggtacgccaa aaatggtttg gaaatcgtag
     5461 gtaccaaagt aacgaagacc tatggaatta tccttttcaa agatgcagaa ggaacctacg
     5521 atattgacag cttcatcttt cgagatgaaa tgtacaaacc aatctacttc ttaaatgaca
     5581 gtcctgctta ctttaagaaa attccgaaaa aatggttgaa attctttgtc ggtgatcaag
     5641 aaaaaatggt taagctacaa ctagatagaa ttaaagaaga aagcaataaa ccaaaacttg
     5701 atgacttatt agttgcaggt aaaacttact caatctggga tggatcgtat gtcgctgtct
     5761 atcagtataa actcaaacgt agctttattt ttcgactaca agatggatca ctcactcggt
     5821 tcactcgact atcagcagga gatgttaagg aagtaaccta aaacttaaat acataaacat
     5881 aaacgtgtat acgttta
//
LOCUS       DAPBBV010000088         5342 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.093, whole genome shotgun sequence.
ACCESSION   DAPBBV010000088 DAPBBV010000000
VERSION     DAPBBV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.093"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..2618)
                     /locus_tag="RD486_002727"
     CDS             complement(<1..2618)
                     /locus_tag="RD486_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDT7664416.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISD"
     gene            2764..3339
                     /locus_tag="RD486_002728"
     CDS             2764..3339
                     /locus_tag="RD486_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7664417.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3553..4248
                     /gene="vanR"
                     /locus_tag="RD486_002729"
     CDS             3553..4248
                     /gene="vanR"
                     /locus_tag="RD486_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDT7664418.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4226..>5342
                     /locus_tag="RD486_002730"
     CDS             4226..>5342
                     /locus_tag="RD486_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7664419.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVEL"
BASE COUNT         1665 a         1010 c         1019 g         1648 t
ORIGIN      
        1 tcatccgata tataattcaa aataaagatc gttttttcta ttcggcccat ctcacgtaag
       61 gctgtagcta agctgttttg tcttgaatag gaacctagct tccccataat aagggatgct
      121 gaaactgttc cctcccttat agaatgagct aatcgcaaaa catcctcata attttcttta
      181 atgacctttg tatttatttg tccacgtaaa atggcttcta gttttggata ctcacttgct
      241 ttatctatcg taaataattt tgagtccgat aaatccctta ttcttggggc aaatttaaat
      301 cctaataaat gagtcagtcc gaatatttgg tcagtgtaac cggcagtgtc tgtataatgt
      361 tcctctatgt ttagatccgt ctcatgatgt aacaaaccat ccaaaacatg aatcgcatct
      421 cttgaattag tatgaataat ctttgtgtag taagaagaga attgatcact tgtaaatcgg
      481 tagatggtgg ctccttttcc agttccataa tgtggatttg catctgcatg tagtgatgaa
      541 acacctagct gcattctcat accatctgac gaagatgttg taccgtcgcc ccaatagaaa
      601 ggcaattgta atttatgatg aaagtttact aatatggctt gggctttatt catggcatct
      661 tcatacatgc gccattgaga tacattggct agttgcttat atgtaagtcc gggtgtggct
      721 tcggccatct tgctcaagcc aatattcatt cccattccta aaagggcagc catgataatg
      781 attgtttctt ccttatctgg ttttcgatta ttggaagcat gagtgaattg ctcatgaaat
      841 cctgttatat gggccacatc catgagtaaa tcagttaatt ttattcttgg tagcatctga
      901 taaaggcttg cactaaattt ttttgcttct tctggaacat ctttttctaa gcgtgcaagt
      961 gatagctttc ctttttcaag agaaacccca tctaacttat tggaattggc agctaaccac
     1021 tttaaccttt cattaaagct gctggttctc tccgttatat aatcttcgaa tgataaacta
     1081 actgataatc tcgtattccc cttcgattga ttccatgtat cttccgaaaa caaatattcc
     1141 tcaaaatccc tatattgtct gctgccaaca atggaaacat ctcctgcccg aacatgctcc
     1201 cgaagttctg ttaaaacagc catttcatag taatgacgat taattgttgt accatcatcc
     1261 tcgtataaat gtcttttcca tcgttttgaa ataaaatcca caggtgagtc atcaggcact
     1321 tttcgctttc cagattcgtt cattcctcgg ataatctcaa cagcttgtaa aagtggctca
     1381 tttgcctttg tagaatgaaa ttccaatact cttaatagcg ttggcgtata ttttcttagt
     1441 gaataaaacc gtttttgcag taagtctaaa taatcatagt cggcaggacg tgcaagttcc
     1501 tgagcctctt ctactgaaga gacaaaggta ttccattcaa taaccgattc taaaacctta
     1561 aaaacgtcta atttttcctc tcttgcttta attaatgctt gtccgatgtt cgtaaagtgt
     1621 ataactttct catttagctt tttaccgttt tgtttctgga tttcctcttg agccttacga
     1681 ccttttgata acaaactaag tatttgccta tcatgaattt caaacgcttt atccgttagc
     1741 tcctgagtaa gttgtaataa atagatggtt aatatcgaat aacgtttatt ttcttgaaag
     1801 tcacggaatg catacggctc gtatcttgag cctaagcgag acagctgcaa caggcggtta
     1861 cggtgcaaat gactaatttg cactgtttct aaatccattc ctcgtatgta ttcgagtcgt
     1921 tctattattt ttagaaaagt ttcgggtgaa ggatgacccg gtggctcttt taaccaaccc
     1981 aatatcgttt tattggattc ggatggatgc tgcgaggtaa taatcccttc aagcttttct
     2041 ttttgctcat ttgttagaga tttactaacc gtattaaata gcttcttttc agccattgcc
     2101 cttgcttccc acaccattct ttcaagtgta gtgatagcag gcagtataat tttgtttttt
     2161 cttagaaaat ctatgcattc atgcagtaga tgaatggcat caccattttc caaagctaat
     2221 tgatgaaggt acttaaatgt cattcgatat tcactcaggg taaaagttac aaagtcgtat
     2281 tcacttcgaa tttctttcaa atgatcccaa agtgtatttt ccctttgagg ataatgatca
     2341 agcgaggatg gactaacacc aatctgtttc gatatatatt gtatgaccga atctgggatg
     2401 cttttgatat gagtgtatgg ccaaccggga taccgaagaa cagctaattg aacagcaaat
     2461 cctaaacggt tttcttccct ccttcgctta ttaactattt ctaaatcccg tttggaaaaa
     2521 gtgaagtagg tccccagtat ccattcatct tcagggattt gcataaaagc ctgtctctgt
     2581 tccggtgtaa gcaattctct acctctcgca attttcattc agtatcattc catttctgta
     2641 ttttcaattt attagttcaa ttatatatca atagagtgta ctctattgat acaaatgtag
     2701 tagactgata aaatcatagt taagagcgtc tcataagact tgtctcaaaa atgaggtgat
     2761 attttgcgga aaatcggtta tattcgtgtc agttcgacta accagaatcc ttcaagacaa
     2821 tttcagcagt tgaacgagat cggaatggat attatatatg aagagaaagt ttcaggagca
     2881 acaaaggatc gcgagcaact tcaaaaagtg ttagacgatt tacaggaaga tgacatcatt
     2941 tatgttacag acttaactcg aatcactcgt agtacacaag atctatttga attaatcgat
     3001 aacatacgag ataaaaaggc aagtttaaaa tcactaaaag atacatggct tgatttatca
     3061 gaagataatc catacagcca attcttaatt actgtaatgg ctggtgttaa ccaattagag
     3121 cgagatctta ttcggatgag acaacgtgaa gggattgaat tggctaagaa agaaggaaag
     3181 tttaaaggtc gattaaagaa gtatcataaa aatcacgcag gaatgaatta tgcggtaaag
     3241 ctatataaag aaggaaatat gactgtaaat caaatttgtg aaattactaa tgtatctagg
     3301 gcttcattat acaggaaatt atcagaagtg aataattagc cattctgtat tccgctaatg
     3361 ggcaatattt ttaaagaaga aaaggaaact ataaaatatt aacagcctcc tagcgatgcc
     3421 gaaaagccct ttgataaaaa aagaatcatc atcttaagaa attcttagtc atttattatg
     3481 taaatgctta taaattcggc cctataatct gataaattat taagggcaaa cttatgtgaa
     3541 agggtgataa ctatgagcga taaaatactt attgtggatg atgaacatga aattgccgat
     3601 ttggttgaat tatacttaaa aaacgagaat tatacggttt tcaaatacta taccgccaaa
     3661 gaagcattgg aatgtataga caagtctgag attgaccttg ccatattgga catcatgctt
     3721 cccggcacaa gcggccttac tatctgtcaa aaaataaggg acaagcacac ctatccgatt
     3781 atcatgctga ccgggaaaga tacagaggta gataaaatta cagggttaac aatcggcgcg
     3841 gatgattata taacgaagcc ctttcgccca ctggagttaa ttgctcgggt aaaggcccag
     3901 ttgcgccgat acaaaaaatt cagtggagta aaggagcaga acgaaaatgt tatcgtccac
     3961 tccggccttg tcattaatgt taacacccat gagtgttatc tgaacgagaa gcagttatcc
     4021 cttactccca ccgagttttc aatactgcga atcctctgtg aaaacaaggg gaatgtggtt
     4081 agctccgagc tgctatttca tgagatatgg ggcgacgaat atttcagcaa gagcaacaac
     4141 accatcaccg tgcatatccg gcatttgcgc gaaaaaatga acgacaccat tgataatccg
     4201 aaatatataa aaacggtatg gggggttggt tataaaattg aaaaataaaa aaaacgacta
     4261 ttccaaacta gaacgaaaac tttacatgta tatcgttgca attgttgtgg tagcaattgt
     4321 attcgtgttg tatattcgtt caatgatccg agggaaactt ggggattgga tcttaagtat
     4381 tttggaaaac aaatatgact taaatcacct ggacgcgatg aaattatatc aatattccat
     4441 acggaacaat atagatatct ttatttatgt ggcgattgtc attagtattc ttattctatg
     4501 tcgcgtcatg ctttcaaaat tcgcaaaata ctttgacgag ataaataccg gcattgatgt
     4561 acttattcag aacgaagata aacaaattga gctttctgcg gaaatggatg ttatggaaca
     4621 aaagctcaac acattaaaac ggactctgga aaagcgagag caggatgcaa agctggccga
     4681 acaaagaaaa aatgacgttg ttatgtactt ggcgcacgat attaaaacgc cccttacatc
     4741 cattatcggt tatttgagcc tgcttgacga ggctccagac atgccggtag atcaaaaggc
     4801 aaagtatgtg catatcacgt tggacaaagc gtatcgactc gaacagctaa tcgacgagtt
     4861 ttttgagatt acacggtata acctacaaac gataacgcta acaaaaacgc acatagacct
     4921 atactatatg ctggtgcaga tgaccgatga attttatcct cagctttccg cacatggaaa
     4981 acaggcggtt attcacgccc ccgaggatct gaccgtgtcc ggcgaccctg ataaactcgc
     5041 gagagtcttt aacaacattt tgaaaaacgc cgctgcatac agtgaggata acagcatcat
     5101 tgacattacc gcgggcctct ccggggatgt ggtgtcaatc gaattcaaga acactggaag
     5161 catcccaaaa gataagctag ctgccatatt tgaaaagttc tataggctgg acaatgctcg
     5221 ttcttccgat acgggtggcg cgggacttgg attggcgatt gcaaaagaaa ttattgttca
     5281 gcatggaggg cagatttacg cggaaagcaa tgataactat acgacgttta gggtagagct
     5341 tc
//
LOCUS       DAPBBV010000089         4868 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.094, whole genome shotgun sequence.
ACCESSION   DAPBBV010000089 DAPBBV010000000
VERSION     DAPBBV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.094"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(207..1169)
                     /locus_tag="RD486_002731"
     CDS             complement(207..1169)
                     /locus_tag="RD486_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7664420.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="RD486_002732"
     CDS             complement(1171..2610)
                     /locus_tag="RD486_002732"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDT7664421.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="RD486_002733"
     CDS             2795..4741
                     /locus_tag="RD486_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HDT7664422.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1559 a          826 c          795 g         1688 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatt
//
LOCUS       DAPBBV010000090         4809 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.095, whole genome shotgun sequence.
ACCESSION   DAPBBV010000090 DAPBBV010000000
VERSION     DAPBBV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.095"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(91..1176)
                     /gene="xerS"
                     /locus_tag="RD486_002734"
     CDS             complement(91..1176)
                     /gene="xerS"
                     /locus_tag="RD486_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HDT7664423.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3252..3770)
                     /locus_tag="RD486_002735"
     CDS             complement(3252..3770)
                     /locus_tag="RD486_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HDT7664424.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1579 a          786 c          731 g         1713 t
ORIGIN      
        1 tataaaaatg ataatgaagc ttgcctttaa agttgggctt ttatctaatt ttagagacag
       61 gcttcattat tatactattt tttactacat ttacaaagcg ttcaaagcat caattgtagc
      121 tgcattgtct atatgagtat ataaagttgt tgtatttgta cttgtatgtc ccaattgttg
      181 ggcagttaat accaatgaat ttgtctgttg atagagtcta gtagccaaag tatgacgtaa
      241 tttatgtgga ctgacttgga ctctgaatcc ttttgaatat tttgctacca tccgttcgat
      301 tgcaataccg gatatacgct tggcttctcc ttgataaatt gctagaaata aagctttttc
      361 gttttctgtt actttgtatc gttctttccg aatagctaga taattagcta aatattccat
      421 tgcaaatgct gctatattta ctgcgtctct cttatttcct tttctagtta ctaccacatt
      481 attcttttct aaagataggt cctctaaatt aatatttaca acctcggaga gtcttaatcc
      541 agatcctaaa atcaatgcat tgatcgccag gtctctttct acatctcgtt gataatagat
      601 caaagctcgt ttgctcaaag tttttttata ttcattggca atataatcta gataattttg
      661 tgtatcttcg tctagaaata attttttctc gattgcgttt gcacgggcag ctaacgtagt
      721 tttatctgtg atagttgcta cttgatccat aggattattt tctaagtatg gttttcctaa
      781 aggattattg gaacttttcg aaagatattt aaatagaacc tttaatgctg tgatatttct
      841 attgatagta gaagtagata gacctaagtt attattatct ttgagcttag tttttgttgt
      901 ctcttttttt acattttcct ttgtgcgacg tttcaaatga gatttgtaca agtttagatc
      961 ataggcagtt aactgtctta tcgaggtgat tgaagtatcg ggaacgatag actcactcag
     1021 aagccattca taaaagagct tataattttt tagatattct aaagtagttc gaggtgattg
     1081 atctttatcc tcacgatctt gaacaaaatc ttttatataa tcgggcatat gaagtatgat
     1141 tgtatctatt ttttgatata tttctgtatt tttcatgtta ttcatccttt cgataagtag
     1201 gggagaggag tatctctata attggactat accaattata gagtgttttg tcaattggta
     1261 tactctgaaa tttattaatt tatttcaaaa aagcagataa ataggtatag atttaataat
     1321 ttaaaataaa tggtatacat gaataggaaa ggaaacagaa ggaggcaatc ttaatttttt
     1381 aaattgtcta aattatatag aaagaacaat ctttctatat aattagacat aagagggact
     1441 acggttgatt tgatattaac aagcgtatat gaatgtatat acaaataaaa aaggggaggg
     1501 agaagttaaa gaaaattcag agaagtgggg cactcagtag tattaacaat ttaaaaggaa
     1561 tttcttaaag aaaatgggtt gcatcctgga gatacaattt ttttagataa agaaaaaatt
     1621 caagcaacaa ttcaaaaaaa tcttaactgc tgagattgat gtagcaatat ctcaatcatc
     1681 aacaaagtac gatcctgcct ttcaaaagct tattgataaa tgtttattca ttataaaaat
     1741 aaaagaaaaa tttatgtcag cttttttcat caaagtggta atgataattc gtctattaat
     1801 tgtatttttt aggaaatatg gtataattgt tttaacgaaa aggtaattca tgatacacca
     1861 aaaaccacta gctggcgggc tagtggtttt cttttacgtt ctattcagat taacgggtag
     1921 gcttactgtc ttttttggca ataattttgc aatcaagcca tttacagatg taatgcgcgg
     1981 atacttctgc taagattgca aaaaacatat cgaaaaggta attcataata caacctcctc
     2041 cccttgccat aataggccgg ggtagcagac agcataaata ttataccata actgaaaatt
     2101 tcattttagt acatttcaat atattgatga accagcacaa taaaacatgc catgactaac
     2161 agaaaaaaac ttattaaacc agatataact tgtaaacatc caactatata gaaaacgtaa
     2221 attttctata tagttggatt aagataacga ctatttattt tatcatattt ttactatacc
     2281 ctatactttt acttggtata tttatgaata atcgcaaatt tacccctata ctactagttt
     2341 gtaagttaga ttaataaaaa tactaaagtt atttgttctt ttattaaata cacctacaac
     2401 ttataaattg atggtattta gataacacga aagaataaaa ataacagctg atagtaaagt
     2461 ttgttgacga ttgctactca atcgaaagtg agttagtgcg tatgaacttg cttctgaaaa
     2521 cttatgaaat gaaagacctt ttacatcttg cagaaatcgg tactgggatt aaactaagca
     2581 ataaaaacta atgttcccct cattctttga acttctacta tttgatttat ttattctgat
     2641 aaatgacgat ttcaccttca ggatcttcaa atcccgtata gaatttattt aagatctctt
     2701 cagtatcagt aataggatag gcgataggcc acataccctt tgatggttag aataaactgc
     2761 tcaaaatctg tatcgtatgt tggctttagc atattaacaa aggctatctc caaattataa
     2821 accataagcg ttgaatcgtt cttaacaatt tcaattcttc ctaacccaaa gtcagaagat
     2881 ataattaccg gacttgcctt acccttcatg tgggttgttg agattccata tttaaaggga
     2941 attgtcggta ctatcggcgg tctgaaaaac atcccaaaaa taaaaaaatc tttcccctgc
     3001 tagtctccta agtccctttg tagcggatat ggcaccataa tctcatttta tcgaagtgag
     3061 tcatggttta tctgttggcc aaccaaaatt gatacaatct aacgatgcac cctctacggc
     3121 attctagggg agtgcacttg cattcaccca ataaaaaccg gcagttagca aagaacttat
     3181 gtagtcgtat gttcttactg ttaacataca agaggtctcc tttccacaat tgcttagcag
     3241 taaacgggaa tttacaaagc taatctcttc cattttctta tctttgttct aaaagtccca
     3301 aatggagcaa ctgtatttac atgaataaat ttatatactt cccatacagc cgttttggtt
     3361 gcctcgtctg cccattttct tttgtgtgca gtgaatagat cttcatcact cattgaatca
     3421 atcatcatgt taatatcatc aatattacga ttgagaattt cctctaattc tttcaatggt
     3481 agatgtgcat aggtatttgt aaaccactta tataactctc ctaactgatt ccatttaaat
     3541 tgatcagaag gcgttttaac agataatcca tttctttcat cattttccca ttttagaatt
     3601 aaattcgtcc aaccaacttg atatgctaaa ttttcagcag gtgttctatc cacttcctca
     3661 actcttttat ccttcaattc ttcaggaata gtttcaaatt ctaaaatata tttagtataa
     3721 gtcctattta tttctttttt taattcttct ttatttttat atgttctcat tatattacct
     3781 ccataaattc ctaattgtct cctttaattc atctataatt tcatccacga tattttaatc
     3841 cgttctacaa tgcatatctg atatgcattg actgtctaac tcatatgtga atgatttata
     3901 aaatatccca acgtctcatc taaagaaatg ttgatcgtca gcaaggagct aaaaaatacg
     3961 aatatatttc ttttgtagta aaatcggact ggtttgcata tcattttctt cgtaaatatc
     4021 aaaatcatgt taactactat caattactaa taaaaactac cactttaagc gttaagaact
     4081 gttaagttta gttaagtgag gatagttcac aaaatccatt gttaaacttc acgaaagtgg
     4141 taaaactcaa aatgctttat ataggattac agcatcgctc tttcttcgat tgcgcgttgg
     4201 gtaaaaaata ttatgaagta aaaattgacg atgacacgtt ccttacggct catcagatga
     4261 aacagctaca aaaacgaaat gatcaactcg aagaaaattt aattctaaaa aagcgattgc
     4321 catattcacg cctcgctcga cgaactatta aaggtcaaga tttacctgaa gatcatcctt
     4381 tttaggaaat tgaagctttt tatgttgcac aatgcattta taatactaca atgatgtttt
     4441 caccagatat tcttctaggg tgcggtgtaa tgaaacagat acacttgcaa aagaaaattc
     4501 accgcgaatt tactaaaatt atgaataatt atgttaatct tccgaaattt ttttccaaaa
     4561 ttaagggatc aagctggtgt tatagattgt ttaaggttgg caaaaaaata acttcttttt
     4621 aaacaattat agaaaaccga tactctgtta agttggttga cacggtgtcg atttttatga
     4681 ctttcttatt ctgaaacttc actaacggac agtacctaaa aagtctatag tatggacgtt
     4741 tacgagtact attttatcaa aaatgctgct catttcaact tatatgtttt agtgaactac
     4801 ccccactta
//
LOCUS       DAPBBV010000091         4805 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.096, whole genome shotgun sequence.
ACCESSION   DAPBBV010000091 DAPBBV010000000
VERSION     DAPBBV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.096"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(52..1200)
                     /gene="nagA"
                     /locus_tag="RD486_002736"
     CDS             complement(52..1200)
                     /gene="nagA"
                     /locus_tag="RD486_002736"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDT7664425.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1276..2112)
                     /locus_tag="RD486_002737"
     CDS             complement(1276..2112)
                     /locus_tag="RD486_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7664426.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2296..3513)
                     /locus_tag="RD486_002738"
     CDS             complement(2296..3513)
                     /locus_tag="RD486_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7664427.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3662..3841)
                     /locus_tag="RD486_002739"
     CDS             complement(3662..3841)
                     /locus_tag="RD486_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664428.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3896..3979
                     /locus_tag="RD486_002740"
     tRNA            3896..3979
                     /locus_tag="RD486_002740"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3930..3932,aa:Leu,seq:gag)
     gene            complement(4219..4797)
                     /locus_tag="RD486_002741"
     CDS             complement(4219..4797)
                     /locus_tag="RD486_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664429.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1459 a         1001 c          775 g         1570 t
ORIGIN      
        1 accttaaaac caaacttaag aagtttagtt ttaaggttaa cttaaattat attatgcgtg
       61 gaaacgttcc acgccatcta gataagttgc ttccaatgtc atatcagggt tcaatacgat
      121 aaagtctgca tcgcgtcctt gagcgatttt tccacatgta tcatcgattt tacagctgat
      181 tgctggaatc agactagcca tcatgactgc ttgttctggt gttgctaatc cccagtctac
      241 aacattttta attgcttctt tcaatttcaa tatacttcca gctaagttgc cagattctag
      301 acgtgctgtt ccttctttta ctactactgg aaattcgcct aaattgtaat ttccatcagg
      361 catcccaccg gccatcatac agtctgtaat taatgcgaca tgatcatgtc ctgctttttc
      421 cattaggatt cccgcagcat ttggatgtac atgatggcca tcacaaatca attcagaaaa
      481 gacatgttct aaagataata acgcacccac catacctggt tcgcgatgat tcaatccacg
      541 cataccattg aaagcatgga caaatacact tgcgcctgct tcaacagctt tttgcgcttc
      601 ttctagtgta gcattactgt gtcctagaga aacaactact ccttcttcag tcacttgttt
      661 gacaaactct tctacacctt gacgttccgg tgctaaagca atttttttga ttaaaccacc
      721 tgaagcttct tgccattcat ggaaagtatc caaatcagga tccccgaaat aacttgggtt
      781 ttgtgcccct ttgtgttctt ctgtgaagaa aggaccttca aaatagattc ctttgatttt
      841 agctcctggt gcttcctgat acattttgcc gattgtctca gctacatctt ttaaacgttc
      901 tttgcttgac gtcaatgttg ttggtaaaaa tgaagtcact ccacaagata acagaccttc
      961 agacatcact ttgatgcctt ctgcatcatt atccattaca tcatgattca tatagccgtg
     1021 aatatgtgta tctaccaaac caggagcaat ccatttgccg ctttggtcaa tgatgttgac
     1081 ttctccctca ggtagttctt tggtgtattc accaaaaagt ccatcggtaa tttcaagata
     1141 gcctgcatgt ttgacacctg acgctaaaaa gaatttgtca gcatagataa aagttctcat
     1201 tctattctct ccctttgttt ttctacctct aaagtactct tatttagaga agaagtcaag
     1261 aatggtctac accatttaca aattttttga aatttgtttc acagcttgtg ctaagccttc
     1321 atagaatgct gctctttctg gttcttcttt acgcttgtat attaagcttt taagcacaaa
     1381 taaatcattg aggtaatagt agctattctt ctcttgagcc caatagattc cttgattcac
     1441 ctgttctaac gcttcgtcga tttcattttg atggaataag aaatttccat aattataaaa
     1501 aatttgcgaa aattcacttt ttgatcgttc atcagctgat tgatgcagca gttggatgct
     1561 tcgactcaaa tagtagcgtg cttcagccgt ttttcctgcc acaccatata tttttccgat
     1621 acaactaatc agttgtattt ctgtgtcaga aacatggatt ctttcttttt ggctagagta
     1681 gcttaatgct tctttcaaat aataaaggga ctgagagata ttttgacgca acgtgaattc
     1741 gcaaacaccg agataataat aatagcgttg aaagtcagtt gcttgataca gattttcaga
     1801 aatatcagaa gattttagta cttgttctaa cttccgataa tcacgttttt ggaaacaact
     1861 atccaacagt tcaaataatt tatcgtttgt ccgagtagtt tttcgagaga gattcatcac
     1921 atgatcaatc gttaccccta gccgttgaca aatctgcatc atcaccaata cattcggcag
     1981 ttcctcatta ttttcgatcc gacttaatac actttgtgaa caaatatcat gcgaaagcat
     2041 tttttgcgtc attttttgtt cttttcgaat ctctttaatg atcgttccaa aggactcgat
     2101 taacgtttcc ataagtatcc tccccaaaat atgcgtattc gcattctatt cgtattttac
     2161 tttaggaagt cgcaaacttc aagaaaagac ttgcaactaa ataatatact ttagttattt
     2221 aagaaaactc cactagaaag agagcctcag tgtgtttgtc tgtggccctc ctactgaaaa
     2281 atttggtttt taaaatcatt tttggcgata ggttgctagg aattctctca ttttcttagc
     2341 tgtttgtttc aaatcatcca ttttaggaag ataaacgatt cgaaaatgat ctggctggtt
     2401 ccaattaaat ccaccaccat gtacaagtag aatatgatgt tcatgtaaaa agtccaaaac
     2461 gaatttttca tcatccaaaa tattgaatcg ctttgtatca atttttggga atatataaaa
     2521 agcagctttt ggttttacgg ctgaaagacc aggaatatca ttgattgcat tatagatata
     2581 ttctctttgt tcatagatcc ttccgcctgg caggagcagc tcatcgacac tttgataacc
     2641 gcctagcgcg gtttggataa tttgctgaga caatacattg gaacacaaac gcatggagga
     2701 caacatattc agcccttcta tatagccttt gacgtgtgac ttatctccac ttaggaccat
     2761 ccagcctact cgaaatcctg ctacacgatg agatttggat agaccgttca gcgtaacaac
     2821 gaacaaatca ggcgctaatg tagcaatcgg aatatgttct agaccatcca tcactaagcg
     2881 atcatagatt tcgtcggaat aaataatcag gttattttgt cgagctactt caacgatttc
     2941 ttctaataat tcttttggat aaagtgcccc agtaggatta ttaggattaa tgataacaat
     3001 agcttttgtc cgactcgtta tttttgattt gatatcatca atatcaggat accattctgc
     3061 ctcttcatcg caaatataat gaacaggtgt gcctccagct aatgcaatag aagccgtcca
     3121 caacggatag tccggcattg gaaccagtac ttcatctcca ttgtccagca acccctgcat
     3181 acacatcgtg atcaattcgc tcactccgtt gccggtgtag atatcattga tcgtcacatt
     3241 cggaaaatgt ttcagttggc aatattgctc aattgctttt ctagcagaaa agatcccctt
     3301 ggaatctgag tagccttctg agtcacgggc attcatgatc aaatcacgaa tgacttcgtt
     3361 tggtgcttca aatccaaaag gtgcgggatt tcccgtgttc aattttaaaa tactaatgcc
     3421 ctcttcttgc atccgctccg cttcttctag aacgggaccg cgaacatcgt aactgacacc
     3481 ttctaatttg ttggattttt caaattctct catcacttag ccaatccctc atttcaaaaa
     3541 gttagaactt tccaaatttt ttgttattta ctatttcaat atcatactcc atcctagaaa
     3601 attttgccac ttatttagga aaaacgtaag tattaaaaaa acacaaacaa gcgttgagaa
     3661 cttaattgtc atgatagtca ttccatagat tcgctgccca atccattgca attccacaaa
     3721 tgattcctag cataaaacca agcaaaaaac gtccgaatgc aagtccaatc aatacaccta
     3781 agatcattcc cagtcctgaa aattctccgt catatttctc catcttaata agtcctccca
     3841 tttttgagct tgacaactat gtaaaacctc gctatcatta gtgtgttatt attacgcaga
     3901 tgtgttggaa ttggcagaca agcatgattg agggtcatgt gagcgttagc tcgtgtgggt
     3961 tcgagtccca tcatctgcac tacaactcgt gaagttaatt ttgcttcacg agtttttttg
     4021 tttgaacgtt tctttatgcc attatataca tatcactgta tcctttacaa aaagaacgta
     4081 caatcatgta aacagcctga ggtgagtata tgaaggtcgg aaacaagcta ctcgtagaaa
     4141 cttgcaagtg ttaaaacaat taatcgaaaa acgagtaaaa tccctcacct aatactaaag
     4201 cgagggattt tttgtatatt atctgtttat caccgttatt ataaaggtac aaataccaag
     4261 cacggttaat ccaaattgca taaattcatt tttttgtaca ctcatgcttt tcattagctc
     4321 tttaactgcc attagtacta agatggcgat aacaacataa agtatatagt acgtccgcat
     4381 tccggaagcc catactgtgg gagaaaatcc cataattaac cttgaacaaa atcccattat
     4441 catcaaaata actaaaaaaa tagaagtttt cttattgtca aaacttaaat aaattccaac
     4501 aattaaacat agtaataatg ccaagactac taaagtagct atccaagtac ctggataaaa
     4561 aagtgacagt ttcgttccta actctgtaaa gagattattc aggttactac tactccaaat
     4621 cattgccctt ttatttccat tgacgtaagt aaagctttga cccattgtat taccaaaata
     4681 aataatcagg tttaagaaaa acggtaatgc agtcaatata cgcacataat agttttgaca
     4741 tttcctatat gttagaagga aaattaagaa aaatagcaat aaaaataaga tattcatgtc
     4801 taaaa
//
LOCUS       DAPBBV010000092         4525 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.097, whole genome shotgun sequence.
ACCESSION   DAPBBV010000092 DAPBBV010000000
VERSION     DAPBBV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.097"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..218)
                     /locus_tag="RD486_002742"
     CDS             complement(<1..218)
                     /locus_tag="RD486_002742"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7664430.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRPQRSNKP"
     gene            complement(329..583)
                     /locus_tag="RD486_002743"
     CDS             complement(329..583)
                     /locus_tag="RD486_002743"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7664431.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(776..1051)
                     /locus_tag="RD486_002744"
     CDS             complement(776..1051)
                     /locus_tag="RD486_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HDT7664432.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(1023..1976)
                     /locus_tag="RD486_002745"
     CDS             complement(1023..1976)
                     /locus_tag="RD486_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7664433.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            2588..4081
                     /locus_tag="RD486_002746"
     CDS             2588..4081
                     /locus_tag="RD486_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HDT7664434.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            4216..4512
                     /locus_tag="RD486_002747"
     CDS             4216..4512
                     /locus_tag="RD486_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HDT7664435.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
BASE COUNT         1478 a          752 c          792 g         1503 t
ORIGIN      
        1 atcggtttat tagacctttg aggtctatat tttttaacta caatcgacct taaatttaat
       61 tgtttcatta gcttttggac atgtttaaga gatactgaaa tcccttcttt taataaaact
      121 tgatggatct ttgtggcacc atagcgttgt ttattcgtaa aaaaaattgt tgaaatcttc
      181 tttttcaact tattatttct gatttctgta gctgtcaacg gtttattctt ataaaaataa
      241 tagacacttc tagggatttc taataaccga cacaacaaag aaacagtgta atccttacac
      301 catttttcaa taaattgaac aagcgaattt aggttttccg agagaatatg gctgcggctt
      361 tttttaagat ttcaagttcc tcatttaaac gagcattttc ttttctcagt tcagctactt
      421 cttttccagt cagtcctgtg gactgatcag gtaaatataa attcttccat ttgtaaatcg
      481 ttgcttcaga taagccatat tctttcgcta accctcgaac agaacgtcca gtttgattca
      541 gttcaacaat catttgttta aaattttctt catatcgggt cataaaaatt catcctctcg
      601 tagataagtt taatttattc ttgtctctac gaaaagctgt ctaagatttg atactaacac
      661 caaatgttgt atacccccaa acaatacaca tattttgaag gattaggatt aataaagcta
      721 aaaatatagt aagtatacta aatatattta ctatatctag tatacttact atattttaat
      781 cttttgatcg tctattatat ataatccgtt cctcgtcgtt taaagtatca acataggcgt
      841 ccattgcaag tttgactatt tcatacatag gaatatcttt tgcataacta agatcccgaa
      901 tggtttttag tacgggagga tctacttgaa ctggttttct ttctttcgca gtgtactttc
      961 gttcccctaa ctcgacatta atatcatctt taattgaaat atcttcagca ccaattttct
     1021 tcttatcttt gttcgttggt aataatgcca tttagtttaa tctcctttcc aagaggtagg
     1081 atatgattgg ccattgagtc agcatattta ggtgtataat caaatccttc aatatcacca
     1141 tgttgttcat agtattcaat tctttcttct aattctgtaa agatgtctgc aaaaatagcc
     1201 caccatcttc gatctacata atcatttaat tggataccat tctcaccata catttctaac
     1261 cgatccgagc ctttaacaat gcttttaaaa atgtttgatt caccatactt atcaattgtt
     1321 ttttgatagt ttgcgtgttg agaggaacgt cgcactgaga aaagaacagg caaaattcca
     1381 atgatttgaa gatgagactc ttcaaaattc gtgacaatcg gaactaaaac tttattaata
     1441 aaatcttctg ttccttccat tgcgtaccgt tttaattctt gcattgcaat aatataatct
     1501 gcagcagtta agaatgcacg aaccacatta tctgttgatg gtgggcagtc gataaagata
     1561 taatcgaaat tttttctcaa ttcttctaaa ggtttaatga aggccaatga tctcttacga
     1621 cgatcaggat atttttcgga caagtattca ttaagttctt cagatccagg agagccagcc
     1681 ataatatata aatgtggact tacttgagta atacctgaaa cccagtcccc ttttttgatt
     1741 gctgcagaca tggatcgatc aaagctagta atttgatacg ttgatccaat gttggaagta
     1801 gtatttcttt gttggtcata atcaattagc aacacgtctt tttcaaaaag ttgactagaa
     1861 acaatcgcta ataaatcatt gtctgtagtc ttaccaatgc cgccttttct acctgtaagc
     1921 attacaactt ttcctagttt atctgatgtt ttaaatgcag tccgtaagtt ttccatagtt
     1981 ccctccaatt tcctatacta aatatattta gtatacttca tatacttaat atattcgata
     2041 tatctaatat actccaaatt gataagaatt cagactttat aaggaatata gtggatatac
     2101 taaatatatt tgctatattc agtatatcag atatattcaa aatgtcaaaa tatatttgtg
     2161 cgttttgcgt tgacaattta gagtgaaaag aggtaaactt aattctatag aaaccacaga
     2221 taattcacta tttacaaagt agcaaaagca gtggtactct ttaaacagaa aaattacata
     2281 aaaaaaagag acggaaataa ttgattttag cagaatcaat tatttctgaa tcacatggtt
     2341 aggacatgtg ttcacgctcg tctcaagaat atgtaagtag ctaccaacta cttatattaa
     2401 aagttgatcg gatacctttt ccgattgcct ttattctacc aaaaaaaggc gagcaactca
     2461 acagaagaac gtttatttag tgtacttaaa ttaaatattc ttaaacactg aagagagaac
     2521 acatactatg gctgagatta aagctaaact gtgttctctt tttgtttgag aaaggacgtt
     2581 acaatcgatg ttgagcgaaa tttattcagc tattcttaaa aacggcttac gtacatacaa
     2641 atatcgaaac agcaccatga aacctgcagg tcatattgat tccagtagga gtggtgctat
     2701 ctttgcgtac cgtagcaagc aattaatgaa tgttgggcgt ggtatggtca ttacttcgga
     2761 agaagctatt ttagagaacg aaaagaaact aacgcattgg acacctaata cctatcgctt
     2821 tggtacttat gcggatgatt atcgaacagt ggttaaaggt cattctgaga aaaacttaag
     2881 tcaaatcaac acatttgtag ttgatatcga ttcaaaagag aaccatcaag gcgaaattat
     2941 tttagcctgt ttagatcaag tgggctacat gccaacgcta attttagaat cagatcatgg
     3001 ttatcaagtt tattttgtac taaagacacc aggctatgtc acaaagaaaa gcaatttcaa
     3061 ggtgatcgat gtagcaaaaa aaatttcaaa aacaattcgt ctacagttgg ctgaaaaatt
     3121 gtccggagtg gatctaggat gtaaccactt cggaattgct cgattcccac aagaaaataa
     3181 tattgttttt aaagaaatga actatcagta ttcttttgct gactggattc aatggtcgat
     3241 gaagcttgaa tcagatcaaa aaacaaaaga agatcgagaa cgaaaactaa ttgtctttcc
     3301 tgagaaaaaa gaaattcgtc aagtagatga accgtggttc gatatgttac ttcataaagc
     3361 aaacatcgtc ggcggagaag gacgtcttgg tcgaaataat gtgattttca cgctttcttt
     3421 agcttattac tcttcaggtt atgcattgga tacttgcgaa tacaatatgt tcacattcaa
     3481 cgaacggtta caggaaccgc tatctgaagc agaattagta aagattgtac gtagtgctta
     3541 ttctggtaat tatcaagcag caagcagaga attcattatt gaattgtgcc agcaatgggt
     3601 ttcaccaacc ttaaaaaata atgatctgtt cattcaacga cgtggctggt ggaaatttaa
     3661 aaagccacga gatcaaagaa aatatagtca taaaaatgaa tggaaagaag atctattggc
     3721 ttatctaagc gaaaaaagtc ttgctagtga gccttatttg aacctgtcaa aaaaagaatt
     3781 ggcttcacaa ctaacgatgc ccaagcgaac acttgataag atcttaaatg agttacgaga
     3841 ggagaataaa gtcttctaca aggtaacacg aggaagaaat ggcggaatga tcattgcttc
     3901 agtcaaaacg ttgttcgcga gggttattca actaagtaaa gaaaagagac tagattattc
     3961 aacaaggatc acagaggtat ttggactcaa cgagagctta gtagaagaga catttagaca
     4021 attatcaacc cccttgaacc ctcttaaaga agtgaatctt tttgaagtag atacaggttg
     4081 aaaaataaaa ggtgcaaatt gccttataca atatatctat gatacttctg taggtgttgc
     4141 tccctttgcc tagctacgtg taggtggtat acttataact gcgtatgcag tcttatgtat
     4201 catggaggaa gttgtatgtc gttaaaaaat tatgtctatt cacatcctgt taatgtgttt
     4261 atcattggtc gtttgggatt atctgtggaa gtgttctgtg agctttatgg ttttaagcag
     4321 gggactttgt cttcttgggt taccagggaa aaaacagttg cttctttgcc gattgagttt
     4381 cttcatgggt tgtccttagc ttctggggag actatggatc aggtatatga ttgtttgtgt
     4441 gtgttagagc aggagtatat tgagtataaa atagctaacg agttaagaaa aaggaagaag
     4501 tatatccagt agtagttttt attta
//
LOCUS       DAPBBV010000093         4414 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.098, whole genome shotgun sequence.
ACCESSION   DAPBBV010000093 DAPBBV010000000
VERSION     DAPBBV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.098"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(37..1257)
                     /locus_tag="RD486_002748"
     CDS             complement(37..1257)
                     /locus_tag="RD486_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HDT7664436.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1888)
                     /locus_tag="RD486_002749"
     CDS             complement(1277..1888)
                     /locus_tag="RD486_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDT7664437.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="RD486_002750"
     CDS             complement(1931..2863)
                     /locus_tag="RD486_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDT7664438.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3284..4144)
                     /locus_tag="RD486_002751"
     CDS             complement(3284..4144)
                     /locus_tag="RD486_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7664439.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
     gene            complement(4291..>4414)
                     /locus_tag="RD486_002752"
     CDS             complement(4291..>4414)
                     /locus_tag="RD486_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7664440.1"
                     /translation="STTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT         1254 a          888 c          729 g         1543 t
ORIGIN      
        1 tttattcttt atttaaagct ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttgtcaaccg attttatata tttttttata taataaggta
     3001 attttaatat aaaattttat attgtaaaaa aacaaataag ggaaacaaac aacacatttt
     3061 tgtgtgttgc ttatttccct ctaactatcg ttttctattt gatggttaac ctacttaaaa
     3121 taaatactgc aacgacaaac ggagatcaag catgctttgt aacgtatttt acgagaatta
     3181 cgactttatt ttattactct atcttgctgc catacccgtc tatccctaat catctttggt
     3241 gaattttttc aaagttagca taacaaaaat aagtattttt tccttagtta atcaatagta
     3301 tcattttttt catatgattt aattcatcaa ttaatttttt gtttttatta attttagcaa
     3361 aagctagtgc atcttgaatc aattcgagca cttctgcctt cgacttattt ttagcctgtg
     3421 cgttcttcgc taattgggca gcagctcgtg ctaagtaata agtcaaatgg ttatccgaac
     3481 aaatatcgat tgcgtaattt agtagtgcat cacttgtttc caaatcaccg tcttgcgcaa
     3541 aaaaaacacc acaatgaaag acgatattta acacccgcca gatatcttct gttgtacgaa
     3601 tcggatacgt ataaattttt tcaaacactc gattgaaata aacttctgct ttttccaact
     3661 ctttttctct agcatagacc attccaatac ctgtatatgc caataaacga aacaacgtgt
     3721 tggctgtttc tgccatcaac aactgatcaa aatggaacaa cacatccgta attggtgcat
     3781 tcgtaaaaat catttcaaat ccttttagat agtagtaacg tgcaatcagc tcagactcgt
     3841 caattacctt gggatcaatg gctgctaaaa tctgtgtcaa ttgttcatat tcactcgtaa
     3901 tcagtgaaaa ctctgctttt tctagctgtt catcaagttg tgtattgatc acgttcatcg
     3961 aagaaaaaag ttcaactaac ggaagattga ttcgattaca taatttgatt aaaattttta
     4021 acgaagggac ttgaccattg ttctcaaatt tacttaatgt tgcttgtgta caaattcctt
     4081 cagacacttc tttttgagat aagttggcag cctttcttgc cgtaataaat ttttcaatgt
     4141 tcattatttt ctctccaatc agacctcaca cgaaaatcat ttctgtctcg attttagcat
     4201 gttttctttg ggaatgcttt aattggttaa gatatcggtt ctgttgcaaa gttttaaata
     4261 aagaataaaa tcccttacgg tatctatgat ttaagctggg attcccaata ataccttgat
     4321 ttcagtacag accgaaaacc cgaagagagt gccttctttt cgggttttct tatataatcc
     4381 tcgaatggct tccatgcctt taatcgtggt agag
//
LOCUS       DAPBBV010000094         4147 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.099, whole genome shotgun sequence.
ACCESSION   DAPBBV010000094 DAPBBV010000000
VERSION     DAPBBV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.099"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            50..388
                     /locus_tag="RD486_002753"
     CDS             50..388
                     /locus_tag="RD486_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664441.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYEWLADYLNLPDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHRHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            392..754
                     /locus_tag="RD486_002754"
     CDS             392..754
                     /locus_tag="RD486_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664442.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDGLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            975..2381
                     /locus_tag="RD486_002755"
     CDS             975..2381
                     /locus_tag="RD486_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDT7664443.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQTNIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPNLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     HLMADFGWERELVGTNKIKDVHEYKEIMSEISELRQAAVKERESVSDELRYISRQREE
                     NEREKALVASERVKIEEEKKNMLNVKKEMAVIFQKDIVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
     gene            2828..3802
                     /locus_tag="RD486_002756"
     CDS             2828..3802
                     /locus_tag="RD486_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7664444.1"
                     /translation="MSKRGTIVNEWEKLNRISNRRLKYQSLTLPLKMQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMRLNEGNGYLKAVGNNGWQLLDQHEENIAYVEILKF
                     HEGKGRIDFNPNKINQFLSGSMKNFIHDLFLEPHFSRADIACDIVDIPDDFVSQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKIVPPEITTWWRLELQ
                     LRRGKATDWHEMVHESLDSFASPHYFPPNTKVTERIMVKGLLYDHSEWGNLAKNTKKK
                     YRDLLKQESQNDELTNHLRESFAESADDLKRELDTWLQGLDVTEVGAE"
     gene            3799..>4147
                     /locus_tag="RD486_002757"
     CDS             3799..>4147
                     /locus_tag="RD486_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664445.1"
                     /translation="MSNPVEKMTIKNLADELGVSKNTVRNQLVNSGFDLAQYKENGII
                     MLDKELIGVVRSIYRSKSDQFTGQLPVNNTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQ"
BASE COUNT         1445 a          599 c          929 g         1174 t
ORIGIN      
        1 aaaaaaacga tcagttgtta ctagaaaatc aagaattaaa aaatcgaaaa tggtggcaat
       61 tctggaagtg aggtgtgaca tggataaaat tgatttgaga gaagaaacag tcgatagaat
      121 tgaattgatg tatgaatggt tagctgatta tttgaatttg ccggatgaag ataattatag
      181 tgaaatgctt gaacgaatga tggatgttct caactcggtt atcaatgctg atctagcaaa
      241 atcttcagtt ttgactaatg aatttgttca taggcattta gcgcaaacaa ctgatgaatc
      301 agaaaaagaa ttttggttga aattaatgag tcatgttatg cagttaaacc aaatttccgt
      361 tattaattcc aaagaaaagg agatgtagtt tatgggaatg actttagcag atattaaagc
      421 gcaagaagaa aaattaaaaa aagaacaagc gaaacttcgt caacagaaaa aacgcttgat
      481 tgagaaagaa aatgctgcaa tgggcaaggc tcttcgcaag cgttttgggt ttgaatcttt
      541 tgctgatttt gagcggtggt tatcgtcaat ttctgacgat cagcaacacg aaaaaacagt
      601 ggataatgag tggcttgctg atgaaaaatc agcgccaagc gaacgagatt atcccgatga
      661 atctgacggc ttattcggag tgataccgaa taagaaaagt cagatgagtg agagtaaatt
      721 tacgtcaata tttaatgacg tgaatttacg ataagcgatt attttgcgtg aagcaaaata
      781 aagcgtaaaa ggagttgata gcgtgatacg ctttcggctc cttttttcgt tgtcacttgt
      841 gacagcgaaa accctcggag agcgtttgga attgtgacat ctatgtcaca attaggaaaa
      901 cgttactctt tgacaaagag taacagaaag gtttacaatc tttttattag cgacagccga
      961 aggagggttt taacttgggg ttcagtattt cgttcaaaaa gggaacaaag aatacaagca
     1021 tttctcataa taatcgtgag ttaactgata gccaaaaaat caatgactgg cataagcata
     1081 ttgatttcac aaaatcggat gaaaatatct atttagaaca aacaaatatt cgtgaaaaat
     1141 atgaagaatt attcggtgaa gccgtagaaa aatataatgc aaagcagaaa agagccgata
     1201 gaaaaatcga ggactattta gcaaaggttc gcaaggataa aaaattggaa ccacagcgag
     1261 aatttatcgt gcaaattggt actcttgatg attttcgtac tactcgtgat gatggttctt
     1321 ctactggcat atcggaacaa caagcagaac aaaatcgagt gattgccaac aaaattttag
     1381 ttgagtattt caaagaattt aaagaacgga atcctaattt atccgtctac aatgctgtta
     1441 ttcataatga cgaagtaagt ccgcacctgc atttgaatat tgttcctgtt gctgaagggt
     1501 ataaacgggg tgttcaaaag caaccaagtt ttaacaaagc cttgcaacag cagggtttac
     1561 gagcagataa agagaatggt cgagtgattt ggaataattt taggaatcag gaagttgagt
     1621 caattgaaca tttgatggca gattttggtt gggagcgtga gttagtcggt actaacaaaa
     1681 tcaaagatgt tcacgaatat aaagaaatca tgagcgagat ttcagaattg cgtcaagcgg
     1741 ccgtaaaaga gcgtgagagc gtttctgatg agttgaggta tatttctagg caaagagaag
     1801 aaaatgagcg agaaaaggct ctggtggctt ctgagagagt gaagattgaa gaagagaaga
     1861 aaaatatgct gaatgtaaaa aaagagatgg cggtcatttt ccaaaaagat attgttcctt
     1921 tagaaagttt caagaggctt cctgatggtt cgtatcattt atctgggaat gattttgttg
     1981 atttgtatca acgagctacg agagcaacaa atgccaagag aaatgctgat aacatgagtg
     2041 agcaatattt acagatgctt gagcaaaata cagaattaaa tgagtatgta gctgcattgg
     2101 aagaagagcg tcatttgtct ggtagaaaac aattagcaga tttacaagtg gaaaataaaa
     2161 agctgaaaga agaaaatcgc tctttacgcc agcgtttaga gcgattaaaa aacgcatttc
     2221 aaaaatcgat cactcgtttg tctatccgtt ttggtcttgc agaaaaggat atggggcttt
     2281 ctgaggaatt agaagtatta gagcaggaga aaaccttatt ttatcgtcaa aacgtctcac
     2341 agcataaatt agagcgttct gaagatgaga tcgagtggta gttacgatgt gcagtcaacg
     2401 gtaccggagg cggtttgtgc cgaggataag gagttgacgg ctaaaccact agcctattaa
     2461 gctgacattt gctaaaaaat ggccagtcca ttttttggcc aacctagcgt tagcgaagtt
     2521 tgggggcgcc ctttttaaag ggtgcggttt tatgttttta tatatttgca tagcaaaaga
     2581 gaagtgctat tattgagtta gcgaacaaat gaactggaaa aagagaaaaa aataagtcga
     2641 gcaacgctac caacgttctc gacctttacg gaaactactt gtactagctc cgtaactcat
     2701 actcattata cgaatatttt tagatttctt caagactaga gattttttgg taatgaattt
     2761 ttaagagtta cgtgaacttt tgaaaattct ttccagaagt ctctttttct ttgaggagga
     2821 acaaaatttg agtaaacgtg gcacgatcgt gaatgagtgg gaaaaactta accgcatttc
     2881 taacaggcgg ttaaagtatc aaagtttgac ccttccctta aaaatgcagt ggtcaattga
     2941 ccgaattacc atagtcggaa aactgaaaga aaatatttat tatcacactc caaatgatgt
     3001 gttgatttta aattttgaac agcttatgcg tttgaacgaa ggcaatggtt atttaaaagc
     3061 tgttgggaat aatgggtggc aattattaga ccaacacgag gaaaatatag cttatgttga
     3121 gattcttaaa tttcatgaag gaaaagggcg gattgacttt aatcctaata aaatcaatca
     3181 atttttatca ggttccatga aaaatttcat tcacgattta tttctagaac ctcatttttc
     3241 acgtgcggat attgcttgcg atattgtaga tattcccgat gactttgtta gtcagtatcg
     3301 tgtagttgat cctgtgtcct ttaaaccaat ttatgggcgt tctggtaagt tagaaacggc
     3361 atattggggt agtcgtgcca gtgaacgaca aattcgaatg tacaataaaa aattggaaca
     3421 agaaagaaaa cgtaaaattg ttccgccgga aataacgaca tggtggcgac tagaattgca
     3481 gttacgaagg ggaaaagcaa ctgattggca tgagatggtt catgaaagtt tggatagctt
     3541 tgctagtcca cattattttc cgccaaatac taaagttact gaacggatta tggtgaaagg
     3601 tttgctttat gatcattctg agtggggaaa tctagctaag aatacaaaga aaaaatacag
     3661 ggatttgttg aagcaagaaa gtcaaaatga tgaattgacg aatcatttgc gagagtcatt
     3721 tgcggaatcg gcagacgatt tgaaacgaga attagataca tggctccaag gacttgatgt
     3781 aacggaagta ggtgctgaat gagtaatcca gtagaaaaaa tgaccataaa aaatcttgct
     3841 gacgaattgg gtgtatcgaa aaatacagtg cgcaatcaac tggtcaattc agggtttgac
     3901 cttgctcagt ataaagaaaa tggcattatc atgctagata aagagttgat tggtgttgtt
     3961 cggtcaattt atcggtcaaa aagtgatcaa tttactggtc aattaccggt caataacaca
     4021 ggcagtgatt ttcctttaga aaaagagaat gagtttttgc gtgatcaatt agctgagaag
     4081 gacaaacata tttctgaatt aacagaaatg attcgtgatc aacaaaaatt gaccctgctt
     4141 cagcaac
//
LOCUS       DAPBBV010000095         4104 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.100, whole genome shotgun sequence.
ACCESSION   DAPBBV010000095 DAPBBV010000000
VERSION     DAPBBV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.100"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..542
                     /locus_tag="RD486_002758"
     CDS             <1..542
                     /locus_tag="RD486_002758"
                     /inference="COORDINATES: protein motif:HMM:NF024997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7664446.1"
                     /translation="SKENLLNQDFSTETICEKWAADITYIPTKKNGWCYLSSIMDLHT
                     KRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNKI
                     RHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIHS
                     SIHYLTPQEFEELAKEKMA"
     gene            complement(1015..1587)
                     /locus_tag="RD486_002759"
     CDS             complement(1015..1587)
                     /locus_tag="RD486_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7664447.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1603..2208)
                     /locus_tag="RD486_002760"
     CDS             complement(1603..2208)
                     /locus_tag="RD486_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HDT7664448.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(2329..2586)
                     /locus_tag="RD486_002761"
     CDS             complement(2329..2586)
                     /locus_tag="RD486_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDT7664449.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(2579..2848)
                     /locus_tag="RD486_002762"
     CDS             complement(2579..2848)
                     /locus_tag="RD486_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7664450.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(2979..3158)
                     /locus_tag="RD486_002763"
     CDS             complement(2979..3158)
                     /locus_tag="RD486_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664451.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(3539..>4104)
                     /locus_tag="RD486_002764"
     CDS             complement(3539..>4104)
                     /locus_tag="RD486_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664452.1"
                     /translation="EQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEK
                     YIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDD
                     YYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYT
                     YDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         1225 a          830 c          622 g         1427 t
ORIGIN      
        1 tttcaaaaga gaatctctta aatcaggact tttctactga aacgatctgt gagaaatggg
       61 cagctgacat tacgtacatt cctactaaga aaaatggttg gtgttactta tcttcaatca
      121 tggatttaca cacgaaaaga attattagtt atacattttc aaaacgaatg actgtggatt
      181 gtgtcattca aacattgaat aaagcaaaaa tacattatca cattccagaa ggaatgattc
      241 tacacactga cttgggcagc caatacacag caagagaagt ggaacaatgg cttaaaacca
      301 acaaaataag gcattcttat agtagaaaag gaacacctta tgataatgct ggaatcgaat
      361 ctttccatgc ctcattgaaa aaagaagaag tctacacgac tagctactca gattttgaag
      421 aagcaaatcg agcgctattt agctacattg aaggatttta taaccgaaat cgaatccata
      481 gctcgattca ctatctaacc ccacaggaat ttgaagaatt agcaaaagaa aaaatggctt
      541 aaccgtctct actaaaatgt gtccaagata ttgactcaaa tccagtaata tcacaatagg
      601 aatgctgttt attatattag cagcagtgct gatttttatg atagttattt ggttcttaaa
      661 tgaaagatct aaagacaatc aacaccgtag ggatatggag ataaaatcaa tagagtcaat
      721 agattattta tcgataataa cactaaaaaa gccacgttcc taaacgtgac ttacgctgaa
      781 cgatatgtgt tgtttggtag acgaacaaat cgttcattat aaatatatga tggtatccta
      841 atatagtaag cgtggctagc atacctttaa ttactttacc ttttacagtt accatacaca
      901 ttttttgagc agaaatcaag taaataaaaa aatattatat ttcacaacat gctaatagac
      961 tcatatctag aacgcattaa gtatttacct gtctggttcg ctgagacttc ttttttaact
     1021 ttcttcaatt ttcttcttta ttctaaaaag cgtactgcga ctgaaaccgg ttatagcttc
     1081 aacttcctta tacgatttac ctgaagtaag cagttcatat gcgtgcctct tcttcggtgt
     1141 gattgttgct ttcggacgtc cttctctgaa attaggatta ttctttcttg caaacatttt
     1201 tccttcttgg gtacgttcca caatcatatc acgttccatt tctgctacac tcaacaacgt
     1261 ccgtgtcacc attcgcccca tggacgtatt ttcaatcgtt cctagattca aaaccttgat
     1321 cgttacgtta tcatcgagta aaggttcaat gatctctaat gcttctctcg tgttacgagc
     1381 aaatcgatca agcttcgtaa caactatttc atctccaggc ttcagaccag ccaacagctg
     1441 attgaatttt ggccgatccc gttttgtacc cgtaaatttt tctgaaaaaa tattcttctt
     1501 ctctacgccg ttctcaagca actgttgaat ttgttctttt gtactttgag aagcggttga
     1561 gacacgtgca tatccatatt tcgtcatttg gtccacctac ttttacaaat catctatcgt
     1621 atactcagaa tacccttcat agaaatagct gacatcgatt cctttcatat ataactcgcg
     1681 atcgtcaatt ttatcagtca gagcattgga aattagatag cgtatttcca aatcgtttat
     1741 gggacttcgc tccattgcag aaagatagtc tgctttatcg attaagttcc aatctacaac
     1801 tttttgcaat tcttccttta aaatgagatc cagccaaatt ctagtacttc ggccatttcc
     1861 ttctcgaaat gggtgagcga tattcatctc cacatatttc ttgataatct cttcaaaaga
     1921 agtttgtggc atctgatcaa tatgctgtaa cgaatgttct aaatacataa ctggtgcaaa
     1981 tcgaaaattt ccttttgcaa tattgaccga tcggattttt ccggcaaaat cgtaaatatc
     2041 cgaaaataga aattcatgaa tttcagataa acctttaaat gtaccaactt cgatttcatt
     2101 tatttttcca caatcgtaca attctttcgc tttttgttta ctgagttttt cttcaacctt
     2161 agccaactca acttgattgg ttaatcccaa tttattctct aaaatcatgc gaaatctcct
     2221 taactttatg acataagttt atgaaacact ctcaacccca ttatatcgcg attttgttta
     2281 tgtgtcaaaa actattaagt ttctgaccct ttccttactt ccgattggtt aatagtgatc
     2341 ttttgcagaa taaataaata tcgtttcatt ttcaactcta tatatcagtc tatgttcatc
     2401 tgtaattctt ctggaccatt ttccagataa atcatgcttt aatggctcag gttttcctaa
     2461 tccagcaaag ggggaacgat cgatatcttt tattaacttg ttaatctttt ttatattgct
     2521 tttgtttcct tgctcatgcc aataaagata atcatcccaa gcatcatcag accaagcctt
     2581 aatcatcaga ttcaacctcg attaagtcat gtgttttaaa tgcacctttg gagaattgtt
     2641 catctcctcg acgaattttt tccatgacgt aattattaga aagtgttctc aacgtttctt
     2701 gcatagaatc ataatctctt tttgataata caacaactgt atcttctaca tctttacttg
     2761 ttacaataag tgtttcagca tcctcattaa cttgtttcat ataactacgt aaattttggc
     2821 ggaaatttga ataagctact gcttccattc ctttcacccc ttatttattt ctataaaaca
     2881 attgtacatt atattgtaca attaagcaaa tgattaatat tctaacttct tataattaaa
     2941 agtgctatca cttttagttt ttaggataaa aagtgacgtc actttttgag tgctggtacc
     3001 tcaaatcctg ctttttcttg ggcaatcaat aaatctaacg caatacacat aatcctggat
     3061 tcacttttgc cgtacttctg ctttagttgc tgcaattctt tttgtctctt ttcatccaac
     3121 gtaacgggta accgtttatt tcctattgca attggcatta gtactctctc ctttcatcga
     3181 aataacccta tgaaaaatat ggctgcaatc atcttgaata gtagactcac aagggctaat
     3241 acaaagcgcc aaaagatcaa acaaaatacc agtattgcca aaaatactac gaagtttaaa
     3301 tgcacagctg cagcatggcg cataagtatt tcgccaacaa ataggactaa caatagagga
     3361 atgattttat tcatatggat ctccttcttt ctcttaggtt atcgggtgtt gcccgcttat
     3421 ttcgcaccac ctaagcggcg ggggcggttg gagcgattgg tgcgaaataa gaaccattcc
     3481 cttagttact aggttttttg tccttatttc acacattctc acttttcggt ataaatgatt
     3541 attgcctttt tttcctttca aatcgttgat atggcattcg tttacggtca agttcatttt
     3601 ggatttcttc tgtatcgtcg taagtatagg tgtctaaaaa atcagttaaa gtcgtgtacc
     3661 agtcgtcgcc tgggttatct acttcttcta catattccct caaaaatgct tcgggtacag
     3721 cgagttcata atccattccc attaacacga tagattccgt tccacacgtc aaaaatctag
     3781 taaatacaag gtaataatcg tctatcgtcg catctttgct gtttagctct tccatttctt
     3841 cttccattaa ttccatgctc tcaaaaattg aataatattc tgattctgag taatagtgtt
     3901 tcctgcaaat cgtgtagctg acaaagtttt cgaccagctc actcctttct aggtaaacat
     3961 tcatgatgta tttttctgtt tctagtcgta gaagctccgt tccttttttt accgtttcag
     4021 gacgacgttt atacacgtct aaacgattat ggctgactgt gaccttcgtt tgactcgttt
     4081 cactttccaa atacaattgt tctt
//
LOCUS       DAPBBV010000096         4047 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.101, whole genome shotgun sequence.
ACCESSION   DAPBBV010000096 DAPBBV010000000
VERSION     DAPBBV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.101"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            234..1109
                     /locus_tag="RD486_002765"
     CDS             234..1109
                     /locus_tag="RD486_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7664453.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1213..1977
                     /locus_tag="RD486_002766"
     CDS             1213..1977
                     /locus_tag="RD486_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HDT7664454.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            1964..3406
                     /locus_tag="RD486_002767"
     CDS             1964..3406
                     /locus_tag="RD486_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7664455.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            3417..>4047
                     /locus_tag="RD486_002768"
     CDS             3417..>4047
                     /locus_tag="RD486_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HDT7664456.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIY"
BASE COUNT         1331 a          591 c          855 g         1270 t
ORIGIN      
        1 tcttatagag agttgctata ttttttttgt ttttatgtaa ttacctccaa atcaattcga
       61 tacaagtatt atcataaaac gagtaaaaaa gatattgata acgcttttat tatgtgttaa
      121 actatttttg taaattatgt agggtgctac tattcaatta ggcacgacct aagaaagggt
      181 tctttcttag gtcgtttttt gtctttaaaa attgtttgga gacaaaaata tgtatgaagg
      241 agtctgcaag ttgttttgtt ttatcatata gaggaggtga attaacggtg tatgtgatga
      301 aaaagctgaa tcataatgct gtattgatcg atgacgatgg aatagaaaaa attgcgatgg
      361 ggaaagggat tggcttttct gctaaagtga gtaagccatt tgatgttgag gatgctgaca
      421 aattatttgt attagattct aaagaaaaga tcaaacgatt cagtgagata gtctcgcaga
      481 ttccaatcga atttatggat tttgcggaag aagtgattga actgataaca gctaggatct
      541 cctctccatt agattcaaat atctatatta cattgacaga tcatatttat tttgctattc
      601 aacgaaaaag agaagataga gatgtcacag caattatgtt gccagaaatg agattccttt
      661 atccaaatga atatgatata gcagtagaag tggtcgagcg aatcaatcat cgatatcaaa
      721 ccgagttagg gtcaaatgaa gtaggattca tcactatgca tatcattaat gctgagctag
      781 gagagcctaa tagtttaaag agcttaaaaa tagtagaaat gacgaccacg attttgtccc
      841 atctagaaaa atcctattca aacgtttatg ataaagaatc actgacttat catcgcttaa
      901 tggttcatat caaattcctg gttaaacgct tgatttatca ggaagaaacg ccagtagaaa
      961 atattggttt ttttactgaa acatttaaac atagcaaagc gtattgtaca gcactaaaga
     1021 ttaaagatat catcgaacag caatttcaac ttgccattca agaaaatgaa atcatctatt
     1081 tggcaattca tctagcaaga atctattaaa ataagggcgt aactatctat aggcgcaacc
     1141 aaatgacaca tagtaaatgg actatgatta tttggttgcg cctattttag tagaaaaaag
     1201 aaggagaatg aaatgggaaa agtgattttt aattcggatg attttggcta tagccatggt
     1261 gtgaattatg ggattatgga tgcttatcag cgaggaattt tgacatcaac tacattgatg
     1321 gcaaatatgc cgggtttcga gcatgctgtg aaactaagaa aggaaatgcc taggctaggt
     1381 gtaggagtcc atttaacatt gacgtgtggc aaaccactcc tcaaaactgt cgatactctt
     1441 atcgaaagcg gagagttcag atccttatct tattatcagc atccatttaa cattgacaaa
     1501 gatcaactgt atcaggaatg gaatgctcag attcaaaaaa tttatcatgc ggggatcata
     1561 ccaactcatt tagacagtca tcatcatact catactttgg atgaaaatca ggaggtagtt
     1621 gttacattag caaaaaaata tgatttgccg gttcggagca actttgaacg aaaagatgaa
     1681 gttcgtcatg tcgattattt tgagccttgt ttcgatgtcg taggagaaac tgatgaaaaa
     1741 aaacgacaaa tcaatacgag tgtggaagaa tatttggcaa gtttactcat gatattgaga
     1801 gaagataaaa cgatcgaagt catgtgtcac gcagcgtatt tggatcagga attgttaaat
     1861 ggttcaagtt ttgtgtatcc tcgtacccac caagtcgaat ttttaattca ttcagcattt
     1921 gctcaaaaag tgaaaaatga tcctttgatt gagttagtaa catatgagga tatttaatag
     1981 aggaggaata aaaatgaatg ttaaatcaaa tgtgcagaag cttggaagag cgatgctact
     2041 tccagttgca gcgatgccat tagcgggatt gatcatgcgt ttatcagctg acgatatgct
     2101 gaacatccca gtaattggtg cagctggaaa tgccgttttt ggaaacttgg atatcttatt
     2161 tgctatagga gttgcaatcg gttttgtcaa aaataaggac aaaggaatac ctgcacttac
     2221 tggtttttta gcgattgcta ccttgaaaaa aggcttagaa attatggacc cagaagtgaa
     2281 tatggggatt tttggtggaa ttatttccgg tttagtagcg gcatggacgt ataatcgctt
     2341 taaagaacaa aaattaccag tagttttttc ttattttgcg ggcgaaaaat tcccattgac
     2401 tatggtgatg attctacaaa caatcgcagc tgtttttttg ggctttatct ggccgctcat
     2461 ccaaattggg attgataatt ttgcaaaact gctcgttgat atgggagcat taggtgtggg
     2521 gatatttatg tttttgaatc gtttgctgat cccctttgga ctgcaccatg tgttgaatac
     2581 gtatatttat tacgatttag gaagctatac atctcctagc aaggaagttt tcagaggaga
     2641 gatgacacgc tttatcaacg gagatcctca ggctggactg tttttatcag gtttttttgt
     2701 agtaatgatg tttggtatac cagctatatg tctagctatc tataaagcag cttataaaga
     2761 aaataaagag atggtcaaag gaatcatggg aagcggtgca ggaacttcat ttattgcaaa
     2821 tatcactgag cctgttgaat ttagtttcat gtttctttct cctatgttgt acgtgatcca
     2881 tgcacttttt gccggtttag cagggattgt ctgttactta ttcaatatac gaattggttt
     2941 tacattcgga gcatgtattg ttgattatct catcaatttt cgaatcgcta ccaatgctat
     3001 tttgattctt ccaatcggaa ttttcttttt tgccttgtat tacgttactt tttattattt
     3061 gatcaataag agaaacattc agacattagg acgtgaagct aaggcagagt ttggcaatga
     3121 agtaacctta gaagaaacag agttagggtt agcaagtaaa aattatgaat atatggcaac
     3181 aaaaatgcta caagcgtttg gaggaaaagc caatatcctg gatgtctata gttgtaatac
     3241 acgcctacgg gtagaggtag tggatcccac catggtcgag gaacagcgaa tcaagcaatt
     3301 agggataagc gggatcatta aaccaactga aaaaaattat caaattatca tcggcttaga
     3361 agtgacttat gttatggcag aattcaataa attattagaa gaatagaaag gaaaagatga
     3421 tgatgaaaaa acagattatc actatagctg gaggcgggag tacgtataca ccaggaatcg
     3481 ttcaagccat tttgaacaat gaaaaacggt tgccattatc tgaaatacgt ttatatgata
     3541 ttgatgaaga aagaaatatg gatatgtact tgattgttaa atttatgctg aaaagaaaag
     3601 gtttttcaaa tattcgcatt cgtgcaacgg atgatccaaa gcttgctttt acaggatgcg
     3661 attttgtttt ctcacaaatt cgtgttggag gattggagat gcgagaaaag gacgaaaaga
     3721 ttccacttaa acatggatta gtaggacaag aaacgtgtgg actcggagga tttgcttatg
     3781 ggatgcgctc aatcaaaggt ttattggaaa ttgtcgatca tatacaagac tatgccccca
     3841 aagcatggat tttgaattat acaaatccag agtcgatcgt ttctgaagct gttcgtcgta
     3901 aatatccgaa tgtaaaaatg attaatgcct gtgatatgac tatttcaatt gaagaaacga
     3961 ttgcagtgaa ttacggttat gatcgtaaga attggatcgt tacgtattat ggtttaaacc
     4021 actttggctg gtatacatcg atttatg
//
LOCUS       DAPBBV010000097         3479 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.102, whole genome shotgun sequence.
ACCESSION   DAPBBV010000097 DAPBBV010000000
VERSION     DAPBBV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.102"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..203
                     /locus_tag="RD486_002769"
     CDS             <1..203
                     /locus_tag="RD486_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7664457.1"
                     /translation="PLNENSNGILRRNGLPKSMDFREVNQTFISSVSNQRNHIPRKSL
                     NYRTPIEIFLSYVQEAFYSSLI"
     gene            697..984
                     /locus_tag="RD486_002770"
     CDS             697..984
                     /locus_tag="RD486_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664458.1"
                     /translation="MEIKEIKVRGINKKYVQEIDHRCVELTEQTGQKWSRNDYLKLLI
                     ENDFERPLMDYKKDQFDRLLEKFTDVQLHNTKVLEAYTNEVKNLIEILIAH"
     gene            1002..1424
                     /locus_tag="RD486_002771"
     CDS             1002..1424
                     /locus_tag="RD486_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664459.1"
                     /translation="MVKAIEKHITFYEAHDEVLKHIMETQPTVKNYSEAIRFLCMNYD
                     PEIEKNNNMTNAKLNAMGKEISILIEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKSINESVHARVDPFDPTKFLKR"
     gene            1444..3036
                     /locus_tag="RD486_002772"
     CDS             1444..3036
                     /locus_tag="RD486_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664460.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMGNGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQNSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQIEQERQ"
     gene            3292..>3479
                     /locus_tag="RD486_002773"
     CDS             3292..>3479
                     /locus_tag="RD486_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664461.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         1386 a          537 c          664 g          892 t
ORIGIN      
        1 gcccattaaa cgagaattct aacgggattc tgcgtcgtaa tggactgccg aaatcaatgg
       61 attttagaga agtgaatcag acatttattt ccagtgtcag caatcaacgt aatcatattc
      121 caagaaaatc attgaattac agaacaccaa tcgaaatatt tttgagctat gtacaagaag
      181 cattttattc tagcttaatt tgacaaatca tatgaaaaaa gtatataaaa aatgtttatg
      241 gatcagctat atcaccctag gtatagctgt taaagagatg ggagaaaaca ttaaccacga
      301 ttctaacaca aacatcaagc acataaaaca tttaacactc ctcctttctg gctgaagatt
      361 tcaaccaaac aggaagacag cgtatcaatt atagcataca ctttttctta aattcatttt
      421 tcatatgaca aaatatttcc ttctaatcga caaagttaga aggatttttt attgtctaaa
      481 tacacaaata accttaattt ttaaagagca taaggaaacg tgggaacact ttttaaaaaa
      541 agtgttccaa taggctgtgc ctattacgtt tctctaaaac aaaagtgggt acaaaatatt
      601 cgatttatgg atagtgtatg gatagtaaaa cagctataca tggatagcat atggatagac
      661 tccatagact atccatactt ttttcggagg gtgaaaatgg aaattaaaga gattaaagta
      721 agaggtatta ataaaaaata tgttcaagaa attgatcata gatgcgtaga attaacagaa
      781 caaactggtc aaaaatggag tcgaaatgat tatctaaaac tattgattga aaacgacttt
      841 gaacgtcctt taatggacta caagaaagat caatttgatc gtttattgga aaaatttaca
      901 gatgttcagc tgcataatac aaaagttttg gaagcataca cgaacgaggt caagaactta
      961 attgaaatat taatcgcaca ttaggaagga gataatgttc tatggttaaa gcgatagaaa
     1021 agcatattac attttatgaa gcgcacgatg aagttttaaa acatattatg gaaactcagc
     1081 ctacggtaaa aaactattct gaagccattc gatttttatg tatgaattac gatccagaaa
     1141 ttgaaaaaaa taataatatg acgaacgcaa agttgaacgc aatgggaaag gaaatttcta
     1201 ttttaataga aatggtttca gagtttgcgg atcttcattt gaaagataca ggaatattaa
     1261 ttggtacaaa ttcaactgtc tatcaagaag caaaagagcg tgtggaaggg aaaataaaag
     1321 cgaatcaaac gaagaagtat tctcctaaaa tcaagaaatc aataaatgaa tctgttcatg
     1381 ccagagtaga cccgtttgat ccaacaaagt ttttaaaaag ataaaaagta gaaggggaat
     1441 atgatgaata aatcgcctgc agtcattctc acttgtcaat ttaccttgcc caataaaaaa
     1501 tctttttcaa catacattga ttatatgaca agagaaaaag cgctggaaga aatggaacga
     1561 cgtacgcctg aagaagaaca ggaactgcaa cgaatcaaga atgctttaga ggatttttat
     1621 attcctgaag gagaaacttt ttcggagagt aagacggata aagaattcag cgaaacgtcg
     1681 aatgaagctc aatctttgat gggaaatgga atcaactttg acaagttaga ggaacaagat
     1741 tttaccaaat atctttctta tatgacccgt cactatgcgt tagaacaaaa gaaagaactg
     1801 acgcaaagtg aacaaaaaga ataccaacgc ttgaaccaag caataaaaaa atatcaaaca
     1861 gagccacaca aaaaagcttc aggaaacctt cctggagttt tttctatggc ttcagacgaa
     1921 gtgaaaggaa gtgatctgaa ggagattaag caaatcttcc aaagaggaca acaaaaaggc
     1981 tcaatcattt atcaagatgt tgtctctcat gataattcgt atcttgaaaa aataggattg
     2041 tacgatccca aaacagatac tttagatgaa gaaggattaa aagcagctgg aagaaaaatg
     2101 atggagacat tattcgagaa agagcaactg aacgaaacag gctactggat ggcaacgatt
     2161 caccgtaata ccaaacatat ccatattcat tttgcagttg ttgaaaaaga aaatacgcgt
     2221 aaaccttaca cggaggttga aaatggtgtg agttatatcg taccgaaagg taagagaaga
     2281 caagcaacat tagacgcaat gaagaccaat tatgtacatg agttagaacg tttttcttat
     2341 gaaaaggatc gaatgattgg tatggagaaa cgaaatttat tgacgcggaa aagtgatttg
     2401 cgtaacacct taacaaaagt ggtaaaagag ccagcgcgtt acgatcgaca cgcaatgaac
     2461 ttattaaatg aagtatataa aaccctacct gacaaacgtt cggaatggca ttatggggat
     2521 gaaaaacgaa ccaaactttc accatacaca agagagaaac tcgatgagtt aaccaaatat
     2581 gttttaacaa aagaacctga atatcaagaa tatatacaga tttcaaaagc attgaaagaa
     2641 gaagcaaaaa gtctttatgg ggaaagcaaa agagaatcaa aggatgcaga aaaaaatgct
     2701 ctctttgatt tgaaaaagcg cacaggaaat gccattctaa cagaactgaa gaaacagaat
     2761 agtcaaataa aacctttaat agaaagtatg gatcagatgc aatctattta caatgaacga
     2821 tcctttcgaa cgcttaaaca gttaccaacg aatgaataca aatatagtta cgaagaattc
     2881 atgaagcgca ggaaacaatt ccaacaaaga gttgtcacgc aacggagttt gcgtcaatta
     2941 aatcgaacga ttaatgccca tgaagaaaaa taccacgcaa gtaaagccta cgaagagcaa
     3001 caacgaagaa tccaaataga acaagaaaga cagtaaagac agtaaagtta gcgccttatt
     3061 atactacttg ggaaatgaat gaagagggga tcaataactt cccgtgtaaa agcattgaag
     3121 agtctatttc actcacagaa tgttagttgt taagtgaata aaagaagtaa aagagtcctg
     3181 aacgtaattg tccaggactc tttttttcaa tgaattgttt tccgccaatt caatgagtgg
     3241 tgcgatttgc gactacatta tatcaaaaga aagagaaggg aggaagaaga aatggcttat
     3301 tcaacgattg gagttgttgt tgaaaaaagc agagacaatc tcgtttttgt gacagaaatt
     3361 caaacaggca gagcttttgt cgtcacagac aaagcggcaa aagcgtatca aaatggcgat
     3421 attttaacgt taaatctgac tacgaagacg ttcgtcgatg cggcagaaga ttatccatt
//
LOCUS       DAPBBV010000098         3400 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.103, whole genome shotgun sequence.
ACCESSION   DAPBBV010000098 DAPBBV010000000
VERSION     DAPBBV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.103"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..278
                     /locus_tag="RD486_002774"
     CDS             <1..278
                     /locus_tag="RD486_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HDT7664462.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            421..642
                     /locus_tag="RD486_002775"
     CDS             421..642
                     /locus_tag="RD486_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7664463.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            658..1500
                     /locus_tag="RD486_002776"
     CDS             658..1500
                     /locus_tag="RD486_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664464.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1563..3365
                     /locus_tag="RD486_002777"
     CDS             1563..3365
                     /locus_tag="RD486_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HDT7664465.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
BASE COUNT         1231 a          468 c          702 g          999 t
ORIGIN      
        1 aagaactcat caagctggct aataagggtc aagattatga acatctagca gatgagattg
       61 atgagctgag agacaagcga cagctccttt tagtagaaga tgcctccctc agtggcgaga
      121 acgagcgaat caatgagctg attgaattta tccgcaagaa caaattccgt accttagagt
      181 acgatgataa gcttgtaagg aagataatcc agagcgttac agtctatgaa gaacacttcg
      241 tcatatcctt caaatctggc atcgaaatgg aaatatgaaa accagaagta aatagcctat
      301 gattctacag tagagtcgtg ggttttcttt tgcttgctga ttataataat attttaataa
      361 ctattgttat tataaaccaa atgatttata atattcttag cgtaaacttg gaggtgctgt
      421 atgactacgg cagaaatgat taaagaactg tgtgagcaaa tgaatataag tgtttccgaa
      481 cttgctagac gtattggaca gactccacag aatttcaata agaaattaca acgagaaacg
      541 gtaaccttag atgagttgaa agcgattgct gatgtgctag gtgtcaagtt tgtgcaggct
      601 tttatattgc ctgatggcaa tgaaataaag ataggtaatt aggaggtgta atttgtattg
      661 aaaatcataa caataaatga tgttgagtat gctgtatttg ctgctaatga aggtacttcc
      721 aaaccacaac ctcatatcat agaaacgaaa tctggtacta ttccagaagg aaaacaactg
      781 agtttattaa aagaatatct taagcagaat gatatttccc caataaaagg agcaacaaca
      841 tattggtgca ttgacaaggt tcttaagctt gattcaagta aagaaaaaac tataagtgaa
      901 acaatccata aacaaaaata cttatcttta actgaagaaa atattgagaa acagcataag
      961 tttgtaggtg caagctctaa ttatgggaaa gaaggtctaa taatacatga tgttttgaat
     1021 gcatttcctc ttcataatga tttaaatact attgcgatga agattgcggt aattgatgta
     1081 acaaattcaa cacatctttc tcaatataag agcaggttgt ctctatatga tttggctaaa
     1141 gtaattctgg agattccaaa ttttgatgat cggttggcaa aaggagatcc tcagttgata
     1201 aatattatcg caaggaacat tggtgcagtt aatatgttct catttgcatc caagtactgt
     1261 acatatcata atgtggaagt gtgtgggaga gatgattact ccatctttga tggtatcgtt
     1321 aaaaatactc ttccacacta tatccaagga ctaactacga ataagattga tacgtggcga
     1381 agaagttttg attacgaggc atttaacgaa tgtgttggaa aactacttga tgaaaataat
     1441 atacatattc cttttagaag aagaaagtta gatcacttct tgtggtatgc gaataggtag
     1501 aatataagaa aaaggcatcg taaaagtgat tctggataaa attaatgggg gaggaaataa
     1561 tagtgggatt atttgatttt ctaaagaaaa aacaaggaaa ggttagtaaa cacgttgatt
     1621 atcaactggc ttctagtcta tttcgtactg gtaaagtttt tgctgaaaaa ttggaagtgg
     1681 acatatcaaa tgtagatgag tttcgtaaaa cttttatcgc ttttgatgtg gaaacaactg
     1741 gcctaaattc ttcttcagat agaattgtag agattggtgc ggtgctattt aaagaaggag
     1801 ttccaattca atcattcgga actcttgtca atccaaaagt tagaattgca gcctcagctt
     1861 cggcaataaa taatataact aatgaaatgc taaactctgc tccaaatgag caggaagttt
     1921 acccccagtt ggtagaattt ttaggagatg cactagatgg aaaaatcact atgtgtgcac
     1981 acaatgcaag tttcgatttt ggatttttaa gtaacacatt ttctagactt gggtatgatg
     2041 ctaaaattaa gtatgttgat actctgagtc tctctagaaa acatataaaa ggcattgtaa
     2101 atcataagca agagactgta gcggaatatt tcggattaat aaatgacact gcccatagag
     2161 cggaatcaga tgcagatata tgcggaaaga ttttttgggg tgttttagat attattgagg
     2221 agtcgttgga agaacaaaaa aagcaaatag aaaagatgac tccagacata aaagaacttg
     2281 aagcttgtgc ttttattcaa gatattattg agaaaaaagg atgcgacacc agttggatca
     2341 ggtatcgaaa aaacagtaat aattatgtcg atgtaacttg tctatataca ttcttaaagt
     2401 ttaagtttgc taagaaggga aattacatca ttattagaaa agatgctaca aatggaattg
     2461 atttacctat agaaccttgt actgtaagtg aaggcggtac aacaaatgtg cgagtctatt
     2521 ttcgtagccc ctttgactta acgcctcttt caaattatat tttcagtgct tatagcgatt
     2581 gttataattc tatgaatgaa tatatgagtg ttagtaatta cactaaaaaa gaagcagagc
     2641 aaagccttag tatgctgaaa tctatttcaa aatcagcgat gaaagagtta ttattcgatg
     2701 caaaaaatcg tggatatgat gagactgaag ttaacctaaa tattgaaaaa gtgatatcta
     2761 gagaagatgt aattattaac gggttgcata atcgagtttc attaaacaag atacgaaata
     2821 tagggaattg ggagaaagga tttgatgcag gttatccata ttgggaacgt ggagaaactg
     2881 ctaggaaaaa tggcaaagta gatgaagcta ttgcactttt tgataaagct cgatataacg
     2941 gctatgatgc tcctgcgcta tatgattctt atgctaaagc ttatcgaaaa attaaggatt
     3001 acgataatga aattctcatt cttgatgaag gaattatgcg taaaacacgg cacgatgttg
     3061 gtactttaga ggctcgtagg gataaggcaa ttaagctatt atttgctaaa caagaggcag
     3121 agcggatagc taaggaaaaa tctgattttc taaaagcgaa caaaaaagag gatgcgatta
     3181 gtgagcctag caagaagcgt ggaagacaga ttattcaaat gactgatgat ggaacaataa
     3241 taaaagaatt cgatactata gcttctgctg taaaagaagt tggcgttaac tcaaaaagta
     3301 ttagggatgc tgcaaatgga gttcaaaaac atgctggagg atactactgg aaatacaaag
     3361 attagcagat aatctaagat aacctaggat cttcttaata
//
LOCUS       DAPBBV010000099         3359 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.104, whole genome shotgun sequence.
ACCESSION   DAPBBV010000099 DAPBBV010000000
VERSION     DAPBBV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.104"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..584
                     /locus_tag="RD486_002778"
     CDS             <1..584
                     /locus_tag="RD486_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7664466.1"
                     /translation="AFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIELS
                     KKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMAN
                     SGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHVL
                     EGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(661..1854)
                     /locus_tag="RD486_002779"
     CDS             complement(661..1854)
                     /locus_tag="RD486_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7664467.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1918..2298
                     /locus_tag="RD486_002780"
     CDS             1918..2298
                     /locus_tag="RD486_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDT7664468.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2372..2734
                     /locus_tag="RD486_002781"
     CDS             2372..2734
                     /locus_tag="RD486_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664469.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1145 a          552 c          638 g         1024 t
ORIGIN      
        1 tggcattccc acaactagat ttaaaaagtg aaaaaggacc aaaagctgtt atcaaaacaa
       61 accgtggtga cattactgtt caattattcc ctgaactagc accgaagacg gttcaaaatt
      121 tcattgaact ttccaaaaaa ggttattatg atggcgtgat ttttcaccgc gttattcctg
      181 atttcatgat ccaaggcggc gatccaactg gaacaggaat gggtggcgaa agtatttatg
      241 gcgaaagttt tgaagatgaa ttcagtcgtg aactgttcaa ccttcgcgga gctttatcta
      301 tggcaaattc aggtccaaac acaaacggaa gccaattctt tattgtaaat aacacaaatg
      361 tgccagctaa tatgcttgga caactagaag gtgctggatt cccatcagaa atcattgaag
      421 cgtataaagg tggcggaact ccttggctag atttccgaca tacagtcttt ggacatgtac
      481 tagaagggat ggacacagta gatgaaatcg caaatgtaca acgtggtcca caagaccgac
      541 ctgtacatga tgtagtgatt gaaacaattg aaatttcaga atagtttggt atggtacgga
      601 gtaattatga aaaaggacga aacctagtaa ggtctcgtcc ttttattttg aataaatgat
      661 ttaatcgatt gtctctaaag catacttgat tcgattaagt ccttccagta aagtttcttc
      721 tggacaagca atattcaagc gcatatgccc atgaccggaa ggaccaaacg tgatgccagg
      781 atttaatacg acttttcctt tccgaacaag agtgttctcc aattcttggt cgtctgaaat
      841 ataggcggta aaatctaacc acattaagta agttccttca gggttcatta ttctcacttt
      901 cggaagatac tgttcaaaaa actgattaac tgtttgaaca tttttttcta gataaggaat
      961 cagttggctt aaccattctc cacccgtctc ataagccgct tgggttccaa tcagtccaaa
     1021 agtgttgatt tcgtgctgtt ggttcatcac taaatgtttt tcaaaatcag ctttcatctc
     1081 tggatttttg ataaatacca ttgaattttt gattgcagct agattgaaag tcttggttgc
     1141 ggaagtaaaa gcaactagta gatcatctaa attaggatca atcgttagca tggaagtaaa
     1201 tgtatgatcg aataaagtta aatcttgatg gatctcgtca ctaaacagaa tcacttgatg
     1261 ttttaaacac aattcgctta actgtttcaa ttcttctttg ctccaaacac gccctccagg
     1321 attgtgagga ttgcataaaa tcattgcttt tacattgttt tcttcgattt ttttctccat
     1381 gtcagacaag tccatgatga aatgattatt tttttctagc aaagagcttc gaacgatgtg
     1441 acgttgattt gtttctataa tagaggaaaa tggaggataa actgggtcat gaatcaaaat
     1501 agaatcgcct ggttttgtaa aagtttgtac tgctgcagct aaactggtta acacaccact
     1561 tgtaaaaacg atattttctt tcgtcaactc cacagcatgg tgttggcgtt cccaatgaat
     1621 gatagcctga tatagtttat cagacagagt ggcataacca aagattccat gtttgatgta
     1681 ttcactaaac gctttagcta ccccaccggg agacaagaag tccatatctg ctacccacaa
     1741 aggaagtaag tcatccattt gatatgtctc agcaattgcg tcccatttta cactttctgt
     1801 atcttttctt gaaatctgtt tatcaaattc gatcatctta agacctccag tcattttcgt
     1861 cgcttctttt tttgagctat ttacagtata atgataaatg cgaagagagg gaagtagatg
     1921 acttataaaa ttggacaaat aattgaagga aaagtgacag ggatacagcc ttatggcgca
     1981 ttcgtttctc ttgataacga gacgcaagga cttattcatg tttcagaagt acaatccggt
     2041 tatacgaaaa atatccattc attgttaaaa gtcggacagc cagtaacagt tcagatcatc
     2101 gacattgatg aatattccaa aaaaatcagt ttatctttaa gaacgttaga aaaaacaaat
     2161 ccagctgttc catatcgcag aaaaaggtat ttcacgaata aaaatcgtaa gatcggattt
     2221 accactattg cggagcagtt acctatttgg atagaagaag cattatctga actagaacgg
     2281 aaagaaaata agaaataaaa agtgtatttt ttctgaaaat gtgctagaat ttttatgtaa
     2341 gccatagaac aagttgatcg aggtggaaat tttggcaagc aaaagagttg ctggtacaat
     2401 tatgttgcat ttggaggatg gtactaaaaa atttttggtc cattcaattg atgacaagtt
     2461 ggaatttgcg ttagcggaac tttctgaagg aaagactggt ttagcgaata tacttaattt
     2521 cttaaaagaa atagttcata tcgatgttag caagattagt ttgatggaat tgacaaatac
     2581 acatattaaa gaggaaaatg ttccgttgtt tgtctttgaa actgaacaaa agaatcaaag
     2641 agaagaatta ggcgaaggat atatttggga agaaccaggt caaatgcgct ctgttcttgg
     2701 aacttacgaa gtagagggag tgcctttctt ctaaaataca gattaagcga acaaagaagt
     2761 ttgaattttt ttcaaacttc tttttttatt gtttggtcca aaaaatacaa tgaaatgttc
     2821 tgctaaagat agttttttag tgcattttat tttcaaaata tgttgaaaac ggttgtataa
     2881 cgaataataa taattgatcg aaaaatcatt tcacaaagta atgcttaatt tatagttgac
     2941 caaggaagaa atacatgata aatttaacag cgttgattct gaagtggatg ttatatcaca
     3001 tttctaaaaa atttaaaaaa tagttattga catgttacta acgacatgat aagataactg
     3061 agtcgttaaa aaagaaccac ttgcgaagct tgattctatc gaaaaaaact tcaaaaaagt
     3121 tcttgacaaa taacaaacga taagttatga taaatgagtt gctgaaagat ttcgaaaaac
     3181 gaaatcgaaa aaaactttta aaaaagagtt gacaatcgct tgtctctctg atatgatata
     3241 aaagttgcta cggcagccaa aaacgaatcg ggaaacactc ccgatgaagt agacctttga
     3301 aaactgaaca aagtaagaca aaccaaatgt gtagggcgtc ttgattcaat tcaagacaa
//
LOCUS       DAPBBV010000100         3254 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.105, whole genome shotgun sequence.
ACCESSION   DAPBBV010000100 DAPBBV010000000
VERSION     DAPBBV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.105"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(594..1985)
                     /locus_tag="RD486_002782"
     CDS             complement(594..1985)
                     /locus_tag="RD486_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HDT7664470.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2198..2584)
                     /locus_tag="RD486_002783"
     CDS             complement(2198..2584)
                     /locus_tag="RD486_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HDT7664471.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(2640..>3254)
                     /locus_tag="RD486_002784"
     CDS             complement(2640..>3254)
                     /locus_tag="RD486_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HDT7664472.1"
                     /translation="YIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMKKYS
                     TSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTHRLT
                     ESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDRRLD
                     IEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
BASE COUNT          988 a          695 c          549 g         1022 t
ORIGIN      
        1 atctgttcta acattctcaa ctttgtcagt ttaccatagg aaaatgggaa aatctacgaa
       61 agctctcaac agaatcgtcc tacttaaata cgcttttctt taataataaa taagttggtt
      121 gtttttgtta tttgcgcttt cacttttcgg aataaataat gtgtatttat atggaataaa
      181 taaaaaaaga ggtcgtgact aaaaacaagt cacaacctct ggtaaacggt gttctcctga
      241 caactcctcg gtcacaagac acaatattca acaaacatga gaagctattt tttgaaattg
      301 ctctttgtga ctcagagtga aacggcaggc tcacgacctc tttcttaaac ggtgttcaaa
      361 agcttgcatc tgcggtaata agctcaacca aacgtaaaat atgaggaact atttttgttt
      421 ggctgttctt attacttgat gcagggcagc tttttcacaa cctcttattc acggtgtttc
      481 agaagtagct tctcggaaat aagccgaaat ttcacaaaaa tttgagaaac tatttttagg
      541 aaacttcttc ttatttctta aagctgacca cttctatcac aacctctttt tgactatgca
      601 ttcacatcga tcactttaga atcatcattg atgacatcgc gatctaaatc tttgatgcgt
      661 gcacttgtca cgataccagc taccatgcta ccgctgacgt ttactgctgt acgtgccata
      721 tcgattaatg gttcaacaga gataactaac ccaacgattg ctactggcaa gttcattgcc
      781 cctaaaacga tcagtgaagc aaatgttgcg cccccaccga ctccagctac accaaaagaa
      841 ctgattgtta caattgccac aagcatcaaa ataaattcca aactaaagac attcactcca
      901 gctgctggtg cgacgatcgt tgccaacata gctggataaa cgccagcaca gccgttttgt
      961 ccaatagaca aaccaaaact tgctgagaaa ttagctgttg catcatctac tcctaaagct
     1021 tttgtctgag tctcgatatt caatggcaaa gctccagcac ttgaacgtga agtaaacgca
     1081 aagctcaata ccggaaaggc ttttttgaaa tagttgattg gattgacttt tgcaccaatc
     1141 aaaatcagtg agtggacaat caaaacagca agcaatgcta cgtaagaagc aacgacaaat
     1201 ttacctaaat tgacgatagc tgcaaaatca cttgttgcca aaacgtttgt catcaaagca
     1261 aatactccat aaggtgtcaa acgcaaaaca agcgtcacga tccgcataat gattttatac
     1321 agactgtcga ctaaatctga aaagaatgct gcttcttttg gcgcttttct tttcacgcct
     1381 agataagcga ttccgacaaa tgccgcgaaa ataacgactc caatcgtact tgttgcacga
     1441 ctacctgcta aatcagcaaa aacgttttta gggataaagg ataaaatctg ctgtggaatc
     1501 gataagtttt caactgtttc ctgacgtgtt gccagttcag agattcgtgc tgtttctgca
     1561 gctccttgtg tgaatttagc tccttggagt ccgaacagca ttgttgaacc aattccgatc
     1621 aatgctgcaa tagctgttgt tccaagtaaa gaagtcaata cagtcgcact aattttccct
     1681 agcttttcag aaactttcat ttttgtgaat gcaccaatga tcgaaataaa cactaaaggc
     1741 ataactagca tttgcaagaa tgatacatat ccttgaccta caatcccgat ccattccatt
     1801 gattgagtaa cgactttgtc gtctacacca aagatcaatt gaagcagacc gccaaagacg
     1861 ataccaactc ctaatgctgt aaagacgcgt gttgaaaatt ttgtatggcg cttttgcata
     1921 cgatagaaca catataataa tgccgcaaaa actagaacca ctaaaactgt gatgagtgtt
     1981 gtcatttttc tcctcctcat attattaatg acaagtccat cgaaggaagt aaaggttccc
     2041 gagaatgatt cttcaaccat cctcctgaaa aaattttttt cagtgacttt tatattttag
     2101 acgattttta tcgaaatgac attctttttg cttacaatta gtaataaaaa aacatacctg
     2161 tgatagcttt aatctatcgc aggtatgttt ttactgtcta ttcttgtttt tctgattgaa
     2221 aattcaattt taccccaggc tgatctaagg cgatctctgt cacctcataa gacattcggc
     2281 gtacgatatc gaataacggt gctactagct cgtccacttc ttcttgtgtg acatcatttt
     2341 gaccttcaat tttccgattg aggatatgat tgatctgact cacacttcca gataaaacat
     2401 atgtatcaaa cactaaacgg aactctaagc gtgctcctac gatgctatgt tctttcggat
     2461 agttttcgat cgtttctttt aaaggcgaga agcctacttt caaatctgtt tctacttctt
     2521 ggttcggcaa tctcatatca taatgaaatg cttctacaac ttctttttgt cttctgattt
     2581 ccatataatt ttatcactcc tttatgaaaa ttataacata tctcctttga aaggggatac
     2641 tactttttaa tgatgctctg caaggtaagg atttcattca gatttcctac cacataatct
     2701 gccgggatct cacccagaaa atgatcgatg tcgtaaagac aagtagcgac tcctgcattt
     2761 ttccctgctt cgatatctaa acgacgatcg ccgatcatca tcgtgtctgt tctttctaaa
     2821 tgaaaagtat cgatcaaata atttaaagat gctggatcag gtttacgagg aaagtcctga
     2881 tcgatcccta ctacttcctc aatcagatgt gccaatcgat gttcttttaa caggccccat
     2941 gttgattctg tcaaacggtg ggtcaggatg aaatgacgac cgccgttgtc ttttagcatt
     3001 tccagtactt gtttcgtttc tggaaatgga cgggaaactt ccgtactttc tttttcatat
     3061 cggtgaaata attcattaaa ctctctggca ttcaagtttg attcattgat caaataacta
     3121 gtagaatact ttttcatttt gaagtagatt tcttttttgt ccatactgat accaaaatct
     3181 tttagtgctt gccatgcacc atctaccatt gcgggatacg tatcaaacaa tgtaccatca
     3241 aagtcccata tata
//
LOCUS       DAPBBV010000101         3124 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.106, whole genome shotgun sequence.
ACCESSION   DAPBBV010000101 DAPBBV010000000
VERSION     DAPBBV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.106"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..101)
                     /locus_tag="RD486_002785"
     CDS             complement(<1..101)
                     /locus_tag="RD486_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7664473.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQE"
     gene            complement(175..456)
                     /locus_tag="RD486_002786"
                     /pseudo
     CDS             complement(175..456)
                     /locus_tag="RD486_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
     gene            918..2299
                     /locus_tag="RD486_002787"
                     /pseudo
     CDS             918..2299
                     /locus_tag="RD486_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(2533..>3124)
                     /locus_tag="RD486_002788"
     CDS             complement(2533..>3124)
                     /locus_tag="RD486_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7664474.1"
                     /translation="KEFPIPISWTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGG
                     ALQEGRFIEGFSHPEMGHMLVVPHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQ
                     EVAEDDPYWEIEASYIAQCAYNTTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNG
                     YVETPELSKYIVTPALEDNAGTLGCLALAREAVLHS"
BASE COUNT         1065 a          597 c          543 g          919 t
ORIGIN      
        1 aattcctgaa cttcacgata gcttagattg taacgcaggt agtaaccaac agcgacaata
       61 atgacgtctt ttttgaattg tttgccttta aaatgattca ttactctgcc ctctctgtct
      121 tttttctcaa ttttacacta aaatagattt tttggaaaac tttgcaacag aaccgaaatg
      181 agtatagtat gaattagtaa tttggttttc atctaagttt agctttgatt tactaaaatt
      241 gatatctcga tacatgttca atacatctaa tacaaatcga gaatcttctt tcggaaatgg
      301 ctcagaaaga tcactccaaa tttcatcatc ataatgatac tcgtaacctt ctctcaatat
      361 ttcgattttt ctttcataat aagatctgtt ttggtcctca aatttagcca ataactcaaa
      421 ttgatttact agtgacaatc tctgaaaact gtccattaaa tgtttcttcc tatcttgttc
      481 attaacaaaa aattataagc ccttacaacg aatattatat attaaattta attgtaggtg
      541 aacacgaatt ttataaatat ttatggtgtt aatgacaaat gatatccgac tcctcttcat
      601 acgttctgga ctatttgcta atagattaaa atttcagcat ctatttctga ccataaataa
      661 atgagctgcc gaaaagctgc caaatcagac ttgaaaataa aggatcaaaa acttttaagt
      721 ttctgacccc gtaactcaca cttcaaaatc ttacttaaaa aggagtctga aagaaaaaaa
      781 gagtattcaa aatttttttc taactagcta catcacatct atgcattgac actcaaagaa
      841 ccagaataag tcatcagaaa gcaagggggt gcggacataa tcctggacga aaaaataaac
      901 ttaggaggaa tgtccgtgtg ttttcccaca aagagcgtgt aagggcaatt cagttatttt
      961 taaaatacga ttgctcttat gctgcaacca ttcgagaatt agggtatccg tcgattggtg
     1021 cactacggaa atggtataaa gagtatttgg aatccggaga gctccatcag gagcaccgaa
     1081 aaaaatcaaa gtattctgaa gaacaaaaac gaatagcggt gaatcattat tttgaatatg
     1141 gtcaatgtta tgcacgaacc attcgcatgc ttggttatcc taatagagag tccttgcggc
     1201 agcggtgtga agaacttgca ccaggagcta gaaaactccg aaaaagtgcg gtaaagttaa
     1261 cacaagatca aaaagaagct gtgttgaaaa aattctataa accgcaaact aataggaaaa
     1321 atttagcaga atctgaagga attagtagag ttactctata tcaatggaaa aacacggttc
     1381 ttggaaagga ttttccattg cgtatgactt taaaaaatca ggaaaaacaa aaagagctac
     1441 ttttaaagga agtagaagac ttacaaaaac aagtacacca attacagctc gaaaaaacat
     1501 tactcgaagg agcggctgaa ctgctaaaaa aagaaaaagg cgtcaatctt ctttgtctat
     1561 caaatcaaga aaaaacgata ttgattgatg ccttacgaaa tcagttcacc ttgaaagagc
     1621 ttcttcaaca gctccagttg cctaaaagca gctattttta tcaaaaacaa gcacttgaga
     1681 aaccagataa gtattacaaa gaacgtcaat taattatcac gattttcaat cataacttct
     1741 gtgcgtatgg ttaccgtaga attcaccaag ctttaaaaaa tatgggtaaa aagctttctg
     1801 aaaaagttgt acgtagattg atgactgagg aaaatctatt tgttaaattt tctagacgaa
     1861 aaaagtattc ttcgtatgct ggggaaattt ctcctgcaca ccccaattta ttaaatcgga
     1921 attttaaagc aaagaagcca aatgaaaaat ggttaacaga tattactgaa tttagaattc
     1981 ccgcagggaa aatctactta tcaccacttg tcgattgtta cgatggtgct attgttagtt
     2041 ggactattgg aacaaagcca acttgcttca ctctatgtct aaaaagggtt attcaccaga
     2101 taattcagcg tgcgaaggtt tctttggacg attaaaaaac gagatgtttt atcaacgtga
     2161 ctggaagaat acaacaatca atcagtttat aaacaaattg gatgattata ttcattggta
     2221 taataatcaa cgaattaagt tatctttagg agggctaagc cctcttcaat atcggaagaa
     2281 gcaaagatat atttgttaaa aaggtccaaa aaaatatccg cacccccttt ttttgtaaaa
     2341 aactattgca caatacaagt ggcctacggc tatcgaaatt tccataactt tcgagcaaga
     2401 acttatctca ttcaaggctt gatcttccaa gtaaaacaaa aaccagttaa gcactctgcc
     2461 taactggtta tgactaaatt ttcagttgta tctttctcta ccaacactaa atgtcgaaga
     2521 gccttttttc gtttatgaat gtaagaccgc ttctcgagcc aatgccaaac aaccgagcgt
     2581 tccagcgttg tcttctaatg ctggggtcac gatatatttg cttaactcag gtgtttcgac
     2641 atacccattg accaattttg caaatgcgtc gtggacgttt tgcagcatat ggcgttgttt
     2701 catcacacca ccgccaaaaa tgatcacatc tggagaaaac atcaaggttg tattgtaggc
     2761 acattgagca atataggagg cttcgatttc ccaataagga tcatcttctg caacctcttg
     2821 tccttttttc cctaagcgtt tttcgatggc gggtccagcg gccatccctt ctaaacagtt
     2881 gccatgaaat ggacagctgc cagcaaagtc atcttttgga tgagggacga cgagcatatg
     2941 ccccatttct ggatgactaa acccttcgat aaagcgccct tcttgtaagg caccgccgcc
     3001 aacacccgta ccgatcgtat agtaaacgac actgctcaat cctttgccac tgccgaagac
     3061 atactcacca taggcagccg cattgacatc tgttgtccaa gaaatcggga tcggaaattc
     3121 tttt
//
LOCUS       DAPBBV010000102         3013 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.107, whole genome shotgun sequence.
ACCESSION   DAPBBV010000102 DAPBBV010000000
VERSION     DAPBBV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.107"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            177..359
                     /locus_tag="RD486_002789"
     CDS             177..359
                     /locus_tag="RD486_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDT7664475.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            462..746
                     /locus_tag="RD486_002790"
     CDS             462..746
                     /locus_tag="RD486_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664476.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            762..998
                     /locus_tag="RD486_002791"
     CDS             762..998
                     /locus_tag="RD486_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664477.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            1020..1274
                     /locus_tag="RD486_002792"
     CDS             1020..1274
                     /locus_tag="RD486_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664478.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            1356..1541
                     /locus_tag="RD486_002793"
     CDS             1356..1541
                     /locus_tag="RD486_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HDT7664479.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            1608..2003
                     /locus_tag="RD486_002794"
     CDS             1608..2003
                     /locus_tag="RD486_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HDT7664480.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            1993..2370
                     /locus_tag="RD486_002795"
     CDS             1993..2370
                     /locus_tag="RD486_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664481.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            2392..2766
                     /locus_tag="RD486_002796"
     CDS             2392..2766
                     /locus_tag="RD486_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664482.1"
                     /translation="MKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLWKYKILFL
                     FWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVISDAGIERN
                     IKRVSFKITLNKPTDKKLSEAF"
BASE COUNT         1059 a          507 c          523 g          924 t
ORIGIN      
        1 tttatgttta tgtatatgta tatgaatata aacgtattag gtacgaacac ttttaaattc
       61 ttttctgggc tttgttttta gggtagggct aaaaaaaaca tcaccatctg atccaaaaca
      121 gctcagaaac gcatttaaac gtatctgata ccaatattac agaaggagtg tatcgtatga
      181 ttaacctatt tcttttagtg acagctagta cattattctt tactggaata tcactgataa
      241 tttcctattt gatctataag aaagccgaaa atcacacaag caaagcaatc ggactagccg
      301 tttcatcctt tttaactttg ctgactttat ttgttacttt atcgttttct tttgtttaga
      361 acagctgatc cattagcacc tttttctctt tacattatac acactgttgt gtataatgta
      421 tttgtaaaca agctaattaa cttttaggaa ggagtgacaa gatgctaaca gctactttac
      481 agcaacctac tcacgttgct attgcagaaa gttatacaat taatgcaggg atcgttaaac
      541 agctgatcaa ggatcgagaa ttcaaaaagt ttaacagtcg gcaagcgtat aacagacagc
      601 taaagaaagc tattctaaag cacaaagatt ccttcatcgg gaacttggaa agtgtagatg
      661 ttaaaactgt ttcaacggca ttttcagttg ttgaagtgac tattgacggt cgcttgattt
      721 ctctatttgc ttttggaatt aattgatagg gagtgtgaac tttggaaggt aagacttttg
      781 cagaaatttg gactgaattt attgaggtac caactcgcat tgatccgata acttctgaaa
      841 aggtattgga tgcagacttc tacaatctca aagcaggtac tagccttgaa tgcgtttgga
      901 tgtatttaga agagcatttc aaaggcgtaa cgctcggtca cgtcttatac cacaatggtg
      961 ccgagtggga tgcaattgga aatatccatt tttcttaata taagaaagga gaacacaata
     1021 tgaattatac cgatgaagaa caaatcgctt tggaatacgt tttcacaaat gaagaagggg
     1081 aggaaattga aaaagtcttg atcatttcat caaaagactt ggagaaggct ttggcttatg
     1141 aaccatacga atcaaccgta actgtcattg aattcttaga tacctatact tctaatgata
     1201 cttgggaaat tatgaatatt tgcaacgcta ataacattca atttgctgaa aaaaccaata
     1261 aatcatttta ttagttttgc aataaaacat cctctttttc tattgattcc atacacaaca
     1321 atgtgtataa tagattttgt aaagggaggg tagctatgcc taagacagca agagaaattg
     1381 taaaaattct caaatctaac ggcttcaaaa agactggaca aactggcagt catgcaaaat
     1441 tttataattc caagactaaa agaacggtcg ttgttccgat ccacaatggt gatgtaccac
     1501 taggaacaga agctaatatc tggaagcaag cagggcttta acagccttgc cttcctattt
     1561 ggtattaggc atactatcct ctcttacact agaaaaggag cgaggaaatg aagacaaaaa
     1621 atatttttta tccggcaatc ttcgagaaag aaggagaagc ttataacatc gttttccctg
     1681 acttaccgga aatatctacc tttggaaata gtcttgaaga agcatattta aacgctaagg
     1741 atgctttagg attagcgcta tatagtgtac cagatgcaga atttcctaaa ccatcagcag
     1801 tggaagaatt aactttgaaa gccaaccaag tggtagtaat catccaacta aacattaaac
     1861 ttttccgaag aagcttaaat acaaaaacaa ttagaaaaaa tgttagtgtt ccggaatggt
     1921 tagttctttt agggaaggag aaaaacataa acttctctca actacttcaa aaagcactag
     1981 aagaagagtt gcttgaaaag taaaaaggag accgaaccta tgaaagctac acacttaaac
     2041 tatttctctc gaacgttaat caataatcta ttaaaagata caactggcat tagcgttagt
     2101 accaaacact ttgccaatga tctaattatt tttgaggata ataacttgcg aattgagatg
     2161 tttattgaac aggcaacccc taactcaata cctgaattct gctatacgca cactgaaaaa
     2221 atgaaacatg caaaatcagt taaagatgtt gaagcattaa gtgaatcact aacgaacgct
     2281 ttaaacctcg ttaagaaggc aaaattgtta tttgaatttc aaaccgacta ccacaatgag
     2341 ttgcttgctc aatctgaaat tttagattaa ttgaaacagg agaagagaaa gatgaaacaa
     2401 acacaaacag aaaccgttaa cgatacgctt gctgatcaat tagcaggtta ttataaatta
     2461 tttgagatgg gtaaagcaca gcgcttgatc cactatcttt ggaaatacaa aattttgttt
     2521 cttttttggg aatcaacact aacattctca gttctttttt ataagtcaga tttttataat
     2581 caacacttag ttttagggag ttttttgctt atctacacca ttttgatgct taatttatat
     2641 acctacatca cacttgaaga acacttagta attagcgatg cagggatcga gagaaacatc
     2701 aaaagggtat ccttcaagat cacgttaaac aagcctaccg ataaaaagct ctcagaagcg
     2761 ttctgagagc ttttgacatt ttcttgtata attttatcct aacacattac aaagcaccta
     2821 attcgagctt atatcaagca aatttgctat ttattactca atacatatct aaaaattact
     2881 tgatggaaaa ttagatacat ggtaagcatg aaaagaaaat caatttgagc agatgcagta
     2941 caatacatag caatttaaaa gctctcagaa ggcttctgag agcttttaat atattctttg
     3001 ataatttgtc ttt
//
LOCUS       DAPBBV010000103         2894 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.109, whole genome shotgun sequence.
ACCESSION   DAPBBV010000103 DAPBBV010000000
VERSION     DAPBBV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.109"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            255..1223
                     /locus_tag="RD486_002797"
     CDS             255..1223
                     /locus_tag="RD486_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HDT7664483.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1216..2247
                     /gene="vanA"
                     /locus_tag="RD486_002798"
     CDS             1216..2247
                     /gene="vanA"
                     /locus_tag="RD486_002798"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HDT7664484.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2253..2861
                     /locus_tag="RD486_002799"
     CDS             2253..2861
                     /locus_tag="RD486_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7664485.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          856 a          555 c          707 g          776 t
ORIGIN      
        1 tccagcgatg ccagacttgg ttgataaaag gaggtcctaa gagatgtata taatttttta
       61 ggaaaatctc aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa
      121 cggctcgttc ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga
      181 gaaagatttg acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag
      241 ggttggtctt aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg
      301 cagatgcatt ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca
      361 acgtgtcgga atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata
      421 aatcagagat ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt
      481 ctacccgaag catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca
      541 ctgtcgacaa tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc
      601 ttatggcagt acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt
      661 tggacagcga ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc
      721 agataggcaa agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata
      781 gtcgcagccg aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg
      841 atatcgttac gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac
      901 aaatacagag aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag
      961 atacctatga gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg
     1021 tattggaagg agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc
     1081 aatttttact taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt
     1141 ataccgagca agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg
     1201 aaaggagaca ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag
     1261 gagcatgacg tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa
     1321 tacgagccgt tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct
     1381 tgcgcggaat gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg
     1441 cacggattac ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt
     1501 tcagctttgc atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc
     1561 ggtatccctt ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg
     1621 acatacatcg ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa
     1681 gatgataggc cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca
     1741 ggctcatcct tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa
     1801 tcggcaagac aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc
     1861 ggttgtgcgg tattgggaaa cagtgccgcg ttagttgttg gcgaggtgga ccaaatcagg
     1921 ctgcagtacg gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac
     1981 gcagttataa ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg
     2041 gcaaaaaaaa tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta
     2101 caagataacg gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac
     2161 agtcgttatc cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc
     2221 ttgatcgtat tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg
     2281 aaatagtaca cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa
     2341 aaccggttga cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc
     2401 ttttgaaggc aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt
     2461 accgtcctaa gcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc
     2521 tgacaaagga aagttattat cccaatattg accgaactga gatgatttca aaaggatacg
     2581 tggcttcaaa atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag
     2641 acacgggtga gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc
     2701 atgcggcaaa tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca
     2761 tggaaaacag tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg
     2821 aaccataccc caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg
     2881 acaaactata taag
//
LOCUS       DAPBBV010000104         2674 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.110, whole genome shotgun sequence.
ACCESSION   DAPBBV010000104 DAPBBV010000000
VERSION     DAPBBV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.110"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(531..848)
                     /locus_tag="RD486_002800"
     CDS             complement(531..848)
                     /locus_tag="RD486_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7664486.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYEMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(849..1103)
                     /locus_tag="RD486_002801"
     CDS             complement(849..1103)
                     /locus_tag="RD486_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7664487.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            complement(1363..1581)
                     /locus_tag="RD486_002802"
                     /pseudo
     CDS             complement(1363..1581)
                     /locus_tag="RD486_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2142..2228)
                     /locus_tag="RD486_002803"
                     /pseudo
     CDS             complement(2142..2228)
                     /locus_tag="RD486_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          880 a          481 c          372 g          941 t
ORIGIN      
        1 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtca
       61 ttcctcctgc tatctttttc tattattcta ccttatttga tagtagattt aaaactttgc
      121 aacagaaccc ccatagatat attggacttc ctcttttaaa acacaaaaat aaatactacc
      181 ttatttaggt agtatttatt aaaagttacg tcaattttga ttaaaaatat actacttgaa
      241 cctctcatga gtaaagtcac gaaatttttg ggaatagagc gtacttgata tcttattttt
      301 tcactaatag cagtgtctct tattcaccaa gcgatccccg tagttcctac ggttcttaat
      361 ttttctctag actaatgatt gtatctttag accttcggcc ataacatgga gcaaaataaa
      421 aaggtactaa gtcttatata tcaatcttcg agtaaccgat ggttaacaac catatcgagc
      481 ggcattaatc acccacctgt agaggatgag cgacttttgc ctaattattg ttaaaagcct
      541 agtttcattt gtttagattg gaaaatacgt cctacaagta tctctttttt ttcatggtcg
      601 atccgataaa ataaggcata gcttttgccg atcacgatcc gatatgttgg gatatccatt
      661 tcatagattt cggaaacttc ctcatgcata gttggaaaat ttttggttag ttctaaagcc
      721 ttctggatcg cacctacaaa tctttttatg ctggctggag aaagagcaag ctcattttcc
      781 cattcttcta ttatcgtttc aaggctggtc tggaaacttt tagaataaac tagcgtgtac
      841 tctttcatct attcactcca gccgtatttt ccgaaagctt ttaccatttc aatttctgaa
      901 actgttaaac ctttctcaaa gtcttggaaa ctttcttcaa tcaatttgcg atcgtgttct
      961 tttgctattt gagtagtatc taatatgaat aagttgcctt cttgtttggc ttggatagtg
     1021 tctccgcttt ttaatccaag agagcttgga aggatcactc ccacgctatt gccgatcttt
     1081 ctaaccttta gttcttttcc catgttatca cactcctttt agtttttgat aaataaatta
     1141 taacatgtta taacaacaat tgccaacggt gtttcttaag ggattccact ccatattatt
     1201 attggacaaa ataagccact tagaacgctg aaaacatata caaacgatat caaaatacga
     1261 gtgaactact caccatacac ttccgttaac atccatttaa gtaggtattt ttattatata
     1321 tagatttaac atatgtcggt cggttgattg atatagctaa agttataact caaccgaagc
     1381 cgatttatct acacgaataa agttgcgagt gttctcggct aattcataaa aattgttatg
     1441 tgttccatat agcaatactg gaataacttt attttcttga atctcagaag caactctata
     1501 cacggtgacc gcatacttaa atccattaga ccaattacct gataaacctc cagttttttg
     1561 ctcttactta aatggatcaa tagaaatttc atcacaaacc tatagaggat gagtgacttc
     1621 tgcctaatta cgttaaaaaa tattgaaagt aactctatgt agcaaaaaat atctagaatt
     1681 tcatttcctc aaaactgatc gatattgtat ccaaaaatat atactaccta aaataggtag
     1741 tatatattaa aatatgtgct tttgttagaa aaatcaatac ataaattatc atatctgtat
     1801 atgtcattta ggtattttag ttatgttata atagttttgc tgtctgctac cccggcctaa
     1861 tctggcaagg ggaggaggag atataatgaa ataccttttt gattttgttt ttgcaatcaa
     1921 gccatttgca gaggtaactg cacactacat ctgcaagtgg cttgattgca aaattgccaa
     1981 aaaagacagt aagcctaccc gttaattcta taatatagaa acgtaaaaaa aaaccccatc
     2041 agcctgcacg ctgatggggt ttggtgatat aatgaaatac ctctttgtta ctcataatta
     2101 taccataatt agtcacgaat gcaaccaata gaaaaaacta cttagaacgg tagatcatcg
     2161 ctaataacaa tgcattgtcc accaaatgga ttttgtgaag cattaaatac attgttatta
     2221 attgtcgctg cttttaacta ggcctctccc cttctattat aaaagaagat atatatcatt
     2281 tcttaattac ctactacctt aaaccaaaat ttaagtacta cctaatttaa gtagtactta
     2341 aataatctaa aaaatagtta tcccaattgt tatgatttta taatacgatt atttgtaaca
     2401 aaatgaatat tatataatta aacactacca tatttaggta gtgtttaatt attagcaaaa
     2461 caaaaaatat ttattctatt ctcttaactt caactaagtt atgctgcaca tctttatata
     2521 aatcatatgc aactcattag ctagacaaac tacaagcatg tagttttatc tgttaattat
     2581 gtactaccta aataaagtag tttataatta acaagtatat atatttaaaa atttaaaatt
     2641 aattttttta tgacttgtac aaatttatct gata
//
LOCUS       DAPBBV010000105         2445 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.112, whole genome shotgun sequence.
ACCESSION   DAPBBV010000105 DAPBBV010000000
VERSION     DAPBBV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.112"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(29..577)
                     /locus_tag="RD486_002804"
     CDS             complement(29..577)
                     /locus_tag="RD486_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664488.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(578..1435)
                     /locus_tag="RD486_002805"
     CDS             complement(578..1435)
                     /locus_tag="RD486_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7664489.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(1721..2008)
                     /locus_tag="RD486_002806"
     CDS             complement(1721..2008)
                     /locus_tag="RD486_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7664490.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKIIPVLLCGTHEKFYEQLKKLI"
     gene            complement(1998..2327)
                     /locus_tag="RD486_002807"
     CDS             complement(1998..2327)
                     /locus_tag="RD486_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7664491.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT          709 a          484 c          327 g          925 t
ORIGIN      
        1 aggtagttac ttagttcttc tttgattatt atctaacttt attattcatt ccccaccctt
       61 tgcgcagtga gtcttcggta tcttgtttta tctgactggt agttcttatt atttctccac
      121 gatcatctaa ttctggaaca attggatatt tttctctgaa caagtctagt tctttcacca
      181 cgtcattaaa caaatcttgc ttatcttctt gcgtaagatt ctgtttaata tactcatcta
      241 aagcttttct aagcaattca tctcttgtca tattagtctc atacttttct actaaaactc
      301 tggaagtcgc atttaacaaa gtcgacagtt ttaaaggatg cttggtggaa taaaccttat
      361 caaactttct gattggtgcg ccaacttttt ttgttcttcc tctactctgt ctttcaacat
      421 tggaggaagt ttttatttct tgaacttggt gcacttctaa ttgcttattt tcagatggtg
      481 taattgcttg ctgctttttc tttgcttctg cttctttttt tattttggcg agtcctttat
      541 tgttcccaaa aatatcaagt cctttgatgt cagccaatta ctccacctcc gcataccaat
      601 tctcgtgttc ttccaattct ttcaaaatac tgataaataa ttcgtggctt ttgcgatccc
      661 attgttttaa gagacctttc tttgtcttct ccatcgtaat acctgatccg tcgtatcgtt
      721 ttaagcgcgc atttttgagt acaacatttt taatcaaatg ttccccataa atctcttggg
      781 cttgtttata catttcctga tctactgcgt caccgctttc caacatgaaa ggaataacac
      841 cagcaacata taaatttgta tcaaattctt tcacaaaaaa gtccatatac tcaagatatt
      901 gcatcgcatt tctcatcgat tttacttggg tctgtaagac gacgattgcc cagtccgcaa
      961 tgtacatcgc ggatttacta tatacagaaa tagaaggtgg gacatctaaa tagatgacgt
     1021 caaactcatc aaataatggt tctagctttt ctttcatata tttgaattgg gataatgaat
     1081 cattatattg gtctttgatc caatcatcat acatttcaaa ggacatgtct gctggaagta
     1141 tatagaggtt attgattact ttatagacag cctctttagg tggaagattg tttatcaaca
     1201 cgtcagtcac agtattttcg taaacaatcg gttcaccttc tccgcctcct tcttcgttag
     1261 tgaagttcat atgcgttaag ttcatcacat cagaagtatt tccttgcata tccaagtcaa
     1321 ttatcaaggt tctttttcct tcattaactg ctgattcaaa ccctaacatt tgcgcgcacg
     1381 tacttttacc tacgccacct ttaaaattac cgattacata tttcttcgct accacgttcc
     1441 tacctctttt cttttagcaa tattcatttg atactattat aacatattta tttttagtta
     1501 ctaccaaaaa aaagatatat atgtactacc ttataattaa taaggaaaag gtagtacata
     1561 aataaggaaa agctgaaata tattgattta tagctttcct caaagtaatg acgttattta
     1621 atttatcgag aagcagagaa tactcgcgac tttagtcatg tagacgaatc agattttcga
     1681 taaaaaagaa gccgtccttc ttaagaacga caacaaatca ctagattaat tttttcaact
     1741 gttcataaaa tttttcatgc gttccacata acaatactgg aataatcttg ttttctataa
     1801 tctcgtaagc tactctatat gttgtgcccg catatttaaa cccactagac caaatacctg
     1861 ataaatcccc agttttttgt tcacccttat atggatcaat cgcaatttca tcataaatta
     1921 aattcaaaaa tttttctttc aatggcttct cttttagctt ttttaaatac ttaatgacat
     1981 gttttgaagg aacgatttca taagccaatt tctgttgcca actcctcttt agtcattact
     2041 ttagaattag taagtgtatc ttcagcaata tctctaaagg aagaatgcat tttgtttttt
     2101 ctattcttaa attctacaag aatctcatct ttatcgtagc cttctgcaat tatatcagac
     2161 aaaatatctt cgctaaaatc ataaaattct ttttgtggtt caacaaattc ataaagaata
     2221 ccattctcta ccaactttgc ttcaacttcg actccattag gaacattaaa atctttaggt
     2281 actgtcaaca tgattgaatt gccttgtttt cttgtttttg taatcattta aatccctcat
     2341 ttctaacagt atgtaattac ttagtaaata cattatacca cgagataatg tatttacaag
     2401 taattactgt gactcgtaat gcgtccttgc tgaataaatt tcaac
//
LOCUS       DAPBBV010000106         2400 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.113, whole genome shotgun sequence.
ACCESSION   DAPBBV010000106 DAPBBV010000000
VERSION     DAPBBV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.113"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            207..2069
                     /locus_tag="RD486_002808"
     CDS             207..2069
                     /locus_tag="RD486_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7664492.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="RD486_002809"
     CDS             2069..>2400
                     /locus_tag="RD486_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7664493.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DAPBBV010000107         2389 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.114, whole genome shotgun sequence.
ACCESSION   DAPBBV010000107 DAPBBV010000000
VERSION     DAPBBV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.114"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(493..1785)
                     /locus_tag="RD486_002810"
     CDS             complement(493..1785)
                     /locus_tag="RD486_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7664494.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2059..2319)
                     /locus_tag="RD486_002811"
     CDS             complement(2059..2319)
                     /locus_tag="RD486_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664495.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          788 a          448 c          361 g          792 t
ORIGIN      
        1 ttatattata aattcacatg attatcgaat tttattaagt tagtttttct tgtaaatctc
       61 tgttcccaat gaaactcgag acacttattt taaagaggaa acaatgtggt atttaaatag
      121 ccctcttgta tgggctactc tgtgatactt attagccatt aaactatttt acccacatag
      181 catatatttt gaaatcgttc attccgtaaa ttcaactaaa tatgcctaaa aaaataaaaa
      241 atctaagata gaataagatt tattcagtct tagatggatt tatagcaact ttttcgtaac
      301 aactttaaaa aatacgaaaa gaaagagctg ttttactctg actacgttgc taaattgtcg
      361 tttaatcatt catttaaacc aaatcttttt ttatagaatt cgttttaatc ctcctgaatc
      421 caaaaactat gaaaaccgta attaaatagt taagagtttt taaccaccat aattctctcg
      481 gctattttga aatcagataa attttgatcg gacacatagt tgaataaacc taccgttgtt
      541 acggaaggta aatcgcatac ttttcattct agaggagaag gtctcgttga tcattaactg
      601 attaagcacc atagcccagt tttgaattcg accacctgac cacttcgcgt gtaattcttt
      661 cgtgcgtaaa taaagtagtt ttaggagtgc attctcatta gagaacgctc ctttttttgt
      721 gacttttctg aagctggagt ggacactttc aaccgcattg gtagtgtaca taatttttcg
      781 aatggcacta ccataatcaa atagttgttc aacatgtgca aagttccgtt tccagacatc
      841 tacagcacca gaataatgag accaccgatt ttgaaaactg tcaaaagcag catgtgcagc
      901 gtttagagaa gaagcaccgt agaacttttt catatctcgg cagacttcct tatagtcctt
      961 acttggaata tagcgcaatg catttcgaac aagatgaaca atacagcgct gaacaattac
     1021 cgatggaaag atcgcttttg cgccttcttc gaggccagaa acaccgtcca tcgaaatgaa
     1081 aaagacatct tcgacaccac gtgctttcag ttcatcaaat acttgcatcc agcgattttt
     1141 agattctgtt tgatttaacc ataatcctaa aatctcctta tttcctttga gatcatagcc
     1201 aagaatggtg tatacagcat attctttggc ttcataattt tctcgtaaag taacatacat
     1261 acaatcaacg aatagaaagg cataacactt tgctaggggg cgggcttgcc attcttccaa
     1321 ttcaggaagg acagcgtcag tgatatctga aatcatttca tgggaaatat caaagccata
     1381 aatagcttcg acggttgcgg caatatctcg ttgactcatt cctcgtgcat acatggaaag
     1441 aaccttccct tcgatgtcgg agacatctcg ttttctctta ggaattaact ctggttcaaa
     1501 ggaagcttcc cggtctctag gaacatcaat agctacttca ccaaaactgg ttttaagcgt
     1561 tttagttcca tagccatttc gacggttatc gtgttcctta ggctctttag aatgggcatc
     1621 ataacctaaa tgattattca attctccttg aagcattttt tcaaaaaggg gcccaaacac
     1681 atctttcaaa gcatcttgca tgtcatcgac agattcaggt tgataggcat tcagaatgga
     1741 ttcagctaac ttttcggcat caggatttct tttctttcta gccatcgtgt aatcacctct
     1801 tgatcttatt gtagaaaaag aaaaaccgcg aagcaaccac ctgcctagga ttaatggtta
     1861 cttacacggt ttatattaca ctctcatcat taaaaaagta tctttcgata ttactaaaca
     1921 atgaaattat ctatttgaaa tttaaatctg ataatatatt gagtgttcca atgagggctt
     1981 tgatcctatt atccatatct ttttcagttt taatattgat acacattata agaaaaagaa
     2041 acttttggtt aatttatttc atcccagtgc aaaatataaa aaagtaaaat agaccatagg
     2101 caatagatta acaattaata taatacaagc aaatattcta ttcattgtat ttctgctttc
     2161 aaaaagttct aatattgaaa gtataattcc acaaatgcct ataataagta tgggaataag
     2221 attagaaaat aacaccccga gccaatctgt gaaaattact atatttacta atatccctat
     2281 taacatacct atcatattta ttaaatcaat ttttttcatt agatatttct cctttattaa
     2341 atctgaagta cttatattaa aataattcta aactatttac ctcaaaaag
//
LOCUS       DAPBBV010000108         2367 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.115, whole genome shotgun sequence.
ACCESSION   DAPBBV010000108 DAPBBV010000000
VERSION     DAPBBV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.115"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            152..1453
                     /locus_tag="RD486_002812"
     CDS             152..1453
                     /locus_tag="RD486_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7664496.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(1557..1757)
                     /locus_tag="RD486_002813"
     CDS             complement(1557..1757)
                     /locus_tag="RD486_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7664497.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            2153..2302
                     /locus_tag="RD486_002814"
     CDS             2153..2302
                     /locus_tag="RD486_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664498.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
BASE COUNT          768 a          454 c          408 g          737 t
ORIGIN      
        1 ttcgtacaaa aaaaccgtct tttcttggct ctataatttc taggactgat agaaaatcat
       61 tctatcggtc ccttttgagc atgaaaaaac aaaacataca gaagctccgt tagaattgaa
      121 tcaccacaac acaatcaaag gagcgttctg tatgcctgat cttcatcata tcaaactact
      181 acttggaatc aaagataaaa acattttcat cacaaatgtg gaatcgaaga gcattaagaa
      241 tatcaagagt cttgttgttt ctgcgacgtt aagtaaagaa attcgtcgct gtcctttgtg
      301 taaacagatg aatcatgaag gcatgatcgt taagaacgga aagaaaaaat cgctcattca
      361 acttaataaa tgtgcgaacc aactgactta tcttgcttta gcgaaacaac gctaccactg
      421 tcgtggctgc cacacctatt ttacggcgaa tacctacatt gtcgatagaa actgctttat
      481 cgctaaacaa gtgcgctata aaattttaga agagctaact gaaaaacaag caatgacgac
      541 aattgctaag cattgcggcg tttcttggtc gaccgtttct cggacactcg cttctctgat
      601 ccccatgaca aaagtaaaaa gaaattggtt accgcgttgt ttattaatgg atgaatttcg
      661 ttcactgaaa aatcaagtcg gtccctactc cttttcttgt atggatggcg atactggaaa
      721 attactggat attcttcctt cacggaagaa aaaggctctc gtttcttatt ttatgcaatt
      781 tgaacgacgc gcacgattga aggtaaaggt catcgtgacg gacatgaatg tttcttatgc
      841 ctctctgata aaggaatgtt ttccaaaggc aaaactcgtt gtggatcgtt ttcacattgt
      901 caaacatctc attcgtaaat ttgaggatat tcgcgtacga atcatgaaaa gctttgatcg
      961 aaacgatcca acacaagcca aatattatcg acaattaaag gcgttgtctc ggcttctgat
     1021 caaacgacag gacaagcttg tttatgacaa atggaccaaa tggcgcaatt ttggttgggc
     1081 gtatctcacc gaaagtgaag tggtggatcg tctgctttcg atctctgacg aattacgaat
     1141 cgcctatttt tactatcaag aaattcttca agcgtttcac gacaaagagg cggacacttt
     1201 ctttaaactt gtaagaacga tgcccaattc cgttccaaaa gaactgcatt ctataaaaaa
     1261 agcttttata aactatgaat ccggcattcg tttagccctc gaattgcctt attcaaatgc
     1321 caaaatagaa aatctgcata cccacatcaa agcattgaaa cgagtcgctt atggctttcg
     1381 aagctttcgg aaaatgaaga ccagaatttt cttactaaat aatctgatta cctatgaatc
     1441 aaaaaacatc taaagtagaa aaggaattct accttagatg ttcttatctc actctatcag
     1501 tcctatttga caaagagccc ttttctttcg aaaagacggt taaaagtcaa tttttattaa
     1561 gctttaacaa tgtttgttgc ttgagggcca cgttgaccat cttcaacatc gtaagacact
     1621 gcttggcctt cttctaaagt tttgaagccg tcaccttgga tagctgaaaa atgtgcaaat
     1681 acatcatttc catcttcacc agtgataaag ccaaaacctt tgtctgcgtt gaaccatttt
     1741 actgtaccgt tattcataaa taaattcctc ctgatacgta tcaatgtacg ttttttcgtt
     1801 gcaataaata tttgataggc aaaaggagtt ttatctatgt agatatatcg ctcaaattac
     1861 gtttcaaaat agattactca tttaatatat catgcttttt ctaataacac aaggataatg
     1921 caatgaaata taaaattcat tgtcttctat tgtcttcgaa tcgaagaaaa agttgaataa
     1981 ccgcgattga ttcacttttt gttttcttgt ttatttgctt ttatctgcaa cttttgactt
     2041 taaaatttct taactatgaa aacctttcaa ttggtggtat acttataaat ggaatttcgt
     2101 tatcaacgcg ttcgttgcct ttcagcaagt atttaaagaa aggagaatgg ctatgacatt
     2161 ctataacaaa gatatacaat atcgagtaac cttggataca gatttgaatc tatttgtcgt
     2221 ttttgacaaa gaaaatacca atcatgtagc gacaggtgtt acgatcgaac aagcagtgca
     2281 agaattaaaa aaatctgcat aaggagtgga aaccctcata tggacgattc tcgttcttct
     2341 ctttaaacgc atctactggt agataac
//
LOCUS       DAPBBV010000109         2157 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.117, whole genome shotgun sequence.
ACCESSION   DAPBBV010000109 DAPBBV010000000
VERSION     DAPBBV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.117"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..147
                     /locus_tag="RD486_002815"
     CDS             <1..147
                     /locus_tag="RD486_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7664499.1"
                     /translation="EILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDILSA
                     IRVF"
     gene            complement(434..919)
                     /gene="vanZ"
                     /locus_tag="RD486_002816"
     CDS             complement(434..919)
                     /gene="vanZ"
                     /locus_tag="RD486_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HDT7664500.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(1072..1983)
                     /locus_tag="RD486_002817"
     CDS             complement(1072..1983)
                     /locus_tag="RD486_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HDT7664501.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT          682 a          411 c          306 g          758 t
ORIGIN      
        1 gaaatactta ctgctagtgt cgctacaacg tcacaccatt tacgtttttt aaaaaaacat
       61 ggaatggcaa aatcacgtca agatggaaaa gtagtttatt actctttagc gaatgaagac
      121 atcctttccg ctattcgtgt tttttaaagt tatcagaaaa tctatctatg aaatcttagt
      181 ttgggggtac cgtcaggaaa atgcggattt acaacgttaa ggaaatttat taaagagacc
      241 aattcctcag cactaaaatt gataattggg ctttctttgt tactatagtg ttaggtaagc
      301 tttttacttt atcaccggtt ttcccctcac ttcacaccta cgggcgagtt tccccacatc
      361 ccgttttcca tctaatccaa ttcattcaat atctttatgt gtatgaaaga tcagattgct
      421 tgatttagac atcttacacg taatttattc ttaaatgggt acggtaaacg agcaataata
      481 cgagcaaaag tatacctaca aaaataataa ctctgtctaa ttttttttga ttcatatgct
      541 tattgcttaa accatataat ttcagtccaa gaaagcctcc aacagtattt gtaattacat
      601 ctgttatgtc tgtcgctcca atagcgaaga taaattgaat tatttcaaaa gtaagactta
      661 aaaccagtac aaaagcaaac ttaggtaaaa atccgatttc tttaaaattg acattcaaaa
      721 gcaagccaaa tggaataaag attataacat tatctatcat ctctctgaaa ttcccagtag
      781 cagtaaatgg agtcaagtta agacttcttt gatgataatt aaatactgat aaaatattgt
      841 attgtaattt gaataacact aaccagatta gtgtcactaa atataaagct agcaatcctc
      901 tagataatat ttttcccaat ataatttcct ctaattcttt tgtttaagtt gtatcattag
      961 tatagcaatg tcctagttaa cgtgggtttt aaattaaaaa gctaacgtta ccccaaaagt
     1021 gctagtacaa taatgctgtt cattaatttc gttggtttca ttccgccatc cttacctcct
     1081 tgaattagta tgtgttgatc cgggaaacac tgtcacaatt acaccgtcta tattgtttcc
     1141 tgatatctca taacgaagat tagtcggcac atgaatggtg gtatttttag taacaggata
     1201 ataaaagatc tcatattttt ccccatttac actaacagaa atggtttttt cttcttttag
     1261 gtaatccata tattcctcga gaacgaaatt cttttctttc ataatcgcac tatgtggtaa
     1321 accaacatag cgaatatgcc atggttcata ttgaattcct gttaactctg ttttgtcctc
     1381 tggataacgt aaaatgaacc cgtatttcca agcattttct tctatccact ttccttcagg
     1441 ggctcgttcc attttcgtca agcttgatcc tacatctagt gataaacctg aattatgctc
     1501 actataacct gctggtaagg catactcagc ccccatttct tggtaaagca cactttgctc
     1561 atcaaagtct cgatagccac tattaataat aaaatgacta acgccaccct ttacagcatc
     1621 attgaccatc tctgaaaatt tttgtgctat ttcttttgac atataaatat tactatcaag
     1681 caacccgtat ccatttatta attcgtcatg tttagataaa ttcacgatat ctgacttcac
     1741 actttcttgg cgaacaggat atttactatt gattaatagc agatttcctt gataaacctg
     1801 ttcttctgta attgttttct cttgggtatt ttcagaagtc ccactatttt ctaaatgttc
     1861 tttgggattt tgatcataat tttgaaattc gactttttcc tgagaaaaca gtgcttcatt
     1921 aacgtagtca taacctaagt atattaagaa taacaataac aataaaaaaa acaacttctt
     1981 cattttcagt ctcctcctta actatatagt tggaagtatg aaatatttct agaatcttcc
     2041 ccttaaacgg cacaatctcg tttgagattg tgccgttttg ccccgtaaat tacagtcaat
     2101 tatttcgccc tactggattt actattatca ccaatgtaga tgaattttca taagtga
//
LOCUS       DAPBBV010000110         2123 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.118, whole genome shotgun sequence.
ACCESSION   DAPBBV010000110 DAPBBV010000000
VERSION     DAPBBV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.118"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            250..861
                     /locus_tag="RD486_002818"
     CDS             250..861
                     /locus_tag="RD486_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7664502.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YMNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKN"
     gene            complement(1906..>2123)
                     /locus_tag="RD486_002819"
     CDS             complement(1906..>2123)
                     /locus_tag="RD486_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7664503.1"
                     /translation="PGTPSQRGLNEHSNGLLRKNGLPKEMDFNQVNQGFISSVASKRN
                     HIPRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT          740 a          296 c          369 g          718 t
ORIGIN      
        1 atagagcccc tttaaacggt agttacttag ttcttctttg atttgcgtga aatagagggg
       61 atttattttt ctggttacgt gattaaaaaa tccaaaaaat gagcatagga acggttatga
      121 ttttagggtg tgttttaatg agatattgtg atttcattaa caagtgtatg ataatcggtt
      181 cttttgcaaa gttttccaaa aaatctattt tagtgtaaaa ttgagaaaaa agacagagag
      241 gacagagtaa tgaatcattt taaaggcaaa caattcaaaa aagacgtcat tattgtcgct
      301 gttggttact acctgcgtta caatctaagc tatcgtgaag ttcaggaatt gttatatgat
      361 cgtggaataa atgtttgtca tactacgatt tatcgttggg tacaagagta cagcaaagtc
      421 ctctattatc tttggaagaa gaaaaataga caatccttct attcatggaa aatggacgaa
      481 acctatatca aaattaaggg acgttggcat tatctttatc gtgcaattga tgcggacggc
      541 ttaaccttag atatctggtt acgaaagaaa cgggatacgc aagcagccta tgctttctta
      601 aaacgactcc ataaacagtt tggtgagccg aaagcaattg tgaccgataa agcaccttct
      661 cttggctccg cctttagaaa gttacagagt gtgggtttat atactaagac agagcaccga
      721 actgtgaagt atatgaacaa tttaatagaa caagaccatc gacctattaa acgacgaaat
      781 aaattttatc aaagtctccg tacagcctct tccacgatta agggcatgga gaccattcga
      841 ggaatatata aaaagaactg aagaaatgga acgctcttcg gcttttcggt gtctactgaa
      901 atcaaggtat taatgggaat aacagcctaa gatatttgga gttcagagag ggcgcgtttg
      961 attttcaaac ttcgcaacag aacccattag caatatataa aagaaggtat caagagtcac
     1021 agtgaattta ttccgaaaag tgaaaagagc aaatataaaa tttaataaaa ataagaacta
     1081 aataggaaaa cgtagacgta attttctacg ttttcctttt catatatatt aaatattacg
     1141 gaaaattata taaactaatt tagtgttttg tttgtaattc ctaattttgc tccactttta
     1201 gataattttt aggtctattt aactcattag acattctatg ctcatttttc tccaaatttg
     1261 tttcaactct ttcgtactta attttgcgta tttgaaaatt cttcttttag agtactttta
     1321 ttacgatact agtatgatat atatctacag caaacagtta aaatcttcct aaaataagcg
     1381 aatagcattc ctaaaaccta taaaattttt agatgaagcg acaagtggac aattaataaa
     1441 ctacttgaac atgaaattat ggatcacctt tcaaatttag aaaatggaat tcttatactt
     1501 attgcgcaac atttattgat tgcaaaatta tgtgacaaaa agaactagta gaagaaggaa
     1561 taatggcttg ataataaagt actacctatt aaaggtagta ctttatttaa tttagtataa
     1621 attaacatac tactatattt taggtttcat attatataaa ttaataatat actaccattt
     1681 gttggtagta taatttaaag gtaataagtt attcttttat tactatgttt gggttttata
     1741 gcaaagaaag tttaataaga gtttggacct agcaaacaat attaatgagg tcattaaatc
     1801 ttattatctt tagtgatata atgaaatatc tacacgacaa aattatgatc ttgcgtaaag
     1861 ttataaaata ttaataaaaa tattttatta atattatttg tcaaattaag cgagacaaaa
     1921 ctttccattt acgtaactca aaaaaacttc taatggtgtt tggtaattta gtgattttct
     1981 agggatatgg tttcttttgg acgcaacgga tgagatgaat ccttgattga cttggttgaa
     2041 gtccatttct tttggtagtc cattttttcg gaggagtccg tttgaatgtt catttaatcc
     2101 ccgttgggaa ggcgttcctg ggt
//
LOCUS       DAPBBV010000111         2055 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.119, whole genome shotgun sequence.
ACCESSION   DAPBBV010000111 DAPBBV010000000
VERSION     DAPBBV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.119"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..330
                     /locus_tag="RD486_002820"
     CDS             <1..330
                     /locus_tag="RD486_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7664504.1"
                     /translation="DFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLTNIENKGQQP
                     SFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVTIGKVIQAIY
                     GEKCKFN"
     gene            complement(844..1011)
                     /locus_tag="RD486_002821"
     CDS             complement(844..1011)
                     /locus_tag="RD486_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDT7664505.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(1099..>2055)
                     /gene="tet(S)"
                     /locus_tag="RD486_002822"
     CDS             complement(1099..>2055)
                     /gene="tet(S)"
                     /locus_tag="RD486_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HDT7664506.1"
                     /translation="NNVLGDKKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFE
                     ISDSDPLLQYYVDTVTHEIVLSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPL
                     KKSEFTIDIEVPPNPFWASIGLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRY
                     GCEQGLYGWKLTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLS
                     FEIYVPQEYLSRAYNDASKYCANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNG
                     RSVCLTELKGYQVTNIKSAFQPRRPNNRIDKVRHMFNKINLH"
BASE COUNT          660 a          335 c          346 g          714 t
ORIGIN      
        1 gatttcaaac cattgggtct tgcgattaaa gaagcccgtc ttagtaaagg attgactcgt
       61 gagcaggtag gatcaatgat ccagattgcg ccacgctatt tgacgaacat tgaaaataaa
      121 ggacaacagc caagttttca tgttgtatat gatttagtga ctttgctaaa tatttctttg
      181 gatggattta ttttagggga agaaaacagt cataaaagct ccaaacgtct tcaagtagaa
      241 gcacagttgg attgtctgga tgaagatgaa ttagtgacga ttgggaaagt gattcaagca
      301 atttacggag aaaaatgtaa atttaactag ttcaataata cacaatggat taattaatac
      361 tatcaggaaa gattgattac aaagatgtaa tgaatttttt ctgatttttg ttaatcataa
      421 atagaaaatg aatttatctt tgttacactt aggaactaga gcgaatgata aatagttctt
      481 tggttactct tatcgctgca aagtacagtt cattttttgt tgttgggaaa attttctgga
      541 tttattgcat atcacttcat ccgactaaaa atttttgatt cccatagcga agttcgtttt
      601 tgttccttag gaaaaacttg actgatatac tagttttgaa atgacgagta actctgtact
      661 tcatcaataa tcaagtattg aattttaatt gtatactttt tatgcttgag ggatgtctac
      721 tgtaatacag ctactgcaaa aaaaatcagt acacttattt tcttataaag gatatcaaga
      781 actaagctca atggtatgca tagaaaagaa aaagccgata aaatgagatt ttgatatctc
      841 gaattatcgg ctctgcgtct ttgcgtctgg ctctgtaatt acagttattc taaacttcgt
      901 tatttcaatt aaaatttctt gtctgcattt aggacaaaat agagggaaat tttttaattc
      961 agtatcttcc ctcattttta aacgggtctt attgccacat atagggcaca gtatccacct
     1021 agtatttaca atatctatat cctcctgttc taattaacaa ctcaatattc attttaaaaa
     1081 tttctcttta gttcactatc aatgtaagtt gattttatta aacatatgcc ttactttgtc
     1141 tattctatta tttggacgac gtggttggaa agcagactta atgttagtaa cctgataacc
     1201 ttttaactct gttaaacaga cactgcgtcc atttgtaaag aaagttaaac tgtttcgata
     1261 ctcttgaata caacgggctg gaatttcacc aatgagaatg acctcgttac cttttaactt
     1321 agtatttaaa atatttgcac aatatttgga agcatcatta tatgctctcg aaagatattc
     1381 ttgtggtaca taaatttcga agctaagata tggctctaat aactctgtac cactctttct
     1441 aaaagcctgc tctagtacaa taggcgcaag cattcggaaa tctgctggcg tactgacagg
     1501 gctgtaatat agaccatact taaaacagat cttacagtct gttaatttcc aaccgtacaa
     1561 tccttgttca cacccatagc gtataccttc cataactgca ttttgaaatg attgatttaa
     1621 ataacctaga gaaaccaggc tctcatactg aatgccacta cccaaaggaa gtggtgttac
     1681 agataaacca atagaagccc agaaaggatt tggaggtact tcgatatcaa tggtaaattc
     1741 agattttttt aatggtcttt ccatataaat gacagttggt tttcttgttt ctatctcaat
     1801 atgatatttt tcttgaatca gagtacaagt tacctccatt tggacctcac ctaaaaaaga
     1861 tagcacaatt tcgtgagtta ctgtatctac ataatattgt agaaggggat cactatcgga
     1921 tatttcaaaa agtgcatcta gtaacttttc tctttgtact gatttacatg gttcaattgt
     1981 tgtttgtaac ataggaagag gattctcaag aatttctcta tgtggtaatc tttttttatc
     2041 tccaagtacg ttatt
//
LOCUS       DAPBBV010000112         1948 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.120, whole genome shotgun sequence.
ACCESSION   DAPBBV010000112 DAPBBV010000000
VERSION     DAPBBV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.120"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            25..696
                     /locus_tag="RD486_002823"
     CDS             25..696
                     /locus_tag="RD486_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7664507.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="RD486_002824"
     CDS             755..1195
                     /locus_tag="RD486_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664508.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="RD486_002825"
     CDS             1207..1875
                     /locus_tag="RD486_002825"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDT7664509.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
BASE COUNT          707 a          312 c          400 g          529 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaatt
//
LOCUS       DAPBBV010000113         1928 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.121, whole genome shotgun sequence.
ACCESSION   DAPBBV010000113 DAPBBV010000000
VERSION     DAPBBV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.121"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            198..1163
                     /locus_tag="RD486_002826"
     CDS             198..1163
                     /locus_tag="RD486_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7664510.1"
                     /translation="MSKKGIIVNEWEKLNRISNRRLNVQNLNTPLKLQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMQLNEGNGFVKSVGKNGWQIVDQYEENIAYIELLQF
                     HEGKARIDFNPNKIGQFLASSMKNFIHDLFLEPHFSRADIACDMVNVPDEFIMQYRVV
                     DPVSFKPIYGRSGKLESAYWGSRASERQIRLYNKKLEQETKRKVVPKEVETWWRLEMQ
                     LRRGKATDWHNMVQESLNSFASLHFLPIDTTPTDRIMLAGLMSDQNFWSLLSRNSKYK
                     YRELLKEESQNDELTNHLRETFAESADNLKQELDTWLLGLDVTEK"
     gene            1363..1566
                     /locus_tag="RD486_002827"
     CDS             1363..1566
                     /locus_tag="RD486_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664511.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSAKEGFNLGFSISFKKGTKN
                     TSISHNNRELTDSQKINSLSGRK"
BASE COUNT          630 a          294 c          438 g          566 t
ORIGIN      
        1 aaaaaaatag tcgagcagtg ttgacgcact ctcgaccttt acggaaacta cttcacctag
       61 ttccgtaact caagttcatt atacgaatat ttttaggttt cttcaagcta gagatttttg
      121 gatgtggatt tttagagtta cgtgaactct ggaaattctt tccaagaatc tcttttttcg
      181 ttgaggagga gctatttttg agtaaaaaag gcataatcgt aaatgagtgg gaaaaactta
      241 accgtatttc taacaggcgg ttaaatgttc aaaatttgaa caccccccta aaattacagt
      301 ggtcaatcga ccgaattacc attgttggaa aattgaaaga aaatatttat tatcacacac
      361 caaatgatgt cttgatttta aattttgagc aattgatgca attgaatgag gggaatgggt
      421 ttgtcaaatc agttggtaaa aatggctggc aaattgtcga ccaatacgaa gaaaatatcg
      481 cgtatattga gctcttgcaa tttcatgaag ggaaagcacg aattgatttt aatcccaata
      541 aaattggtca gtttttagcc agttcgatga aaaatttcat tcatgatttg tttttagaac
      601 cccatttttc gcgggcagat atcgcttgcg atatggttaa tgttccggat gagtttatta
      661 tgcaatatcg tgtggttgac ccggtatcgt tcaaaccgat ttacgggcgt tctggaaaac
      721 tagaatcagc ttattggggt agccgtgcca gcgaacgaca aattcggcta tacaataaaa
      781 aattggaaca agaaaccaaa cgaaaagttg taccaaagga agttgagact tggtggcggt
      841 tagaaatgca actacggcgt ggcaaggcaa ccgattggca taatatggtt caagaaagtt
      901 tgaatagttt tgcgagcctg cattttttgc cgattgatac aacacctaca gatagaataa
      961 tgctcgctgg tttaatgtct gatcaaaatt tctggtctct tttgtcgagg aattcaaaat
     1021 ataaatatcg ggaattgctg aaagaagaaa gtcaaaatga tgaattgacg aatcatttgc
     1081 gagaaacgtt tgcagaatcg gcagacaatt tgaaacaaga attagacacg tggcttttgg
     1141 gtttggacgt gacagagaag tgataccgaa taagaaaagt cagatgagtg agagtaaatt
     1201 tacgtcaatg tttaatgacg tgagtttacg ataagcgatt attttgcgtg aagcaaaata
     1261 aagcgtaaaa ggagttgaga gcgtgacacg ctttcggctc cttttttcgt tgtcacttgt
     1321 gacagcgaat accctcggag agcatttgga attgtgacag ccatgtcaca attaggaaaa
     1381 tgttactctt tgtcaaagag taacagaaag gtttacactc tttttattag cgacagcgcg
     1441 aaggaggggt ttaacttggg gtttagtatt tcgttcaaaa agggaacaaa aaatacaagc
     1501 atttctcata ataatcgtga gttaactgat agccaaaaaa ttaatagttt gtctggtaga
     1561 aaataattag cagatttaca agtgggaaat aaaaagctga aagaagaaaa ttgcatttca
     1621 aactacattt tctacaataa ctctaaaatg gcatattttg cgttctgagc ggttttagcg
     1681 tttatttcgt ttagttatcg gcacaatcgg tgaaacacgt tagaggagcg aaaatggagc
     1741 ctgtaaggcg actggtagcg gaacggtcgt gttagattgt gtagccgata gctgaacgaa
     1801 ataaatgctg gcagcgccat tctatttcgg caggaggagg ctcaaggggt tcggggaatg
     1861 aaattccctg aggtcttttt attttttcta gaggagtgct ataatcaaag aaaatgagaa
     1921 aaaagagt
//
LOCUS       DAPBBV010000114         1719 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.122, whole genome shotgun sequence.
ACCESSION   DAPBBV010000114 DAPBBV010000000
VERSION     DAPBBV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.122"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(93..164)
                     /locus_tag="RD486_002828"
     tRNA            complement(93..164)
                     /locus_tag="RD486_002828"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(129..131),aa:Glu,seq:ttc)
     gene            complement(176..249)
                     /locus_tag="RD486_002829"
     tRNA            complement(176..249)
                     /locus_tag="RD486_002829"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(213..215),aa:Ile,seq:gat)
     gene            complement(262..332)
                     /locus_tag="RD486_002830"
     tRNA            complement(262..332)
                     /locus_tag="RD486_002830"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(298..300),aa:Gly,seq:tcc)
     gene            complement(337..409)
                     /locus_tag="RD486_002831"
     tRNA            complement(337..409)
                     /locus_tag="RD486_002831"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(374..376),aa:Phe,seq:gaa)
     gene            complement(413..485)
                     /locus_tag="RD486_002832"
     tRNA            complement(413..485)
                     /locus_tag="RD486_002832"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(450..452),aa:Asp,seq:gtc)
     gene            complement(504..577)
                     /locus_tag="RD486_002833"
     tRNA            complement(504..577)
                     /locus_tag="RD486_002833"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(541..543),aa:Met,seq:cat)
     gene            complement(590..679)
                     /locus_tag="RD486_002834"
     tRNA            complement(590..679)
                     /locus_tag="RD486_002834"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(641..643),aa:Ser,seq:tga)
     gene            complement(702..773)
                     /locus_tag="RD486_002835"
     tRNA            complement(702..773)
                     /locus_tag="RD486_002835"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(738..740),aa:Glu,seq:ttc)
     gene            complement(795..882)
                     /locus_tag="RD486_002836"
     tRNA            complement(795..882)
                     /locus_tag="RD486_002836"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(846..848),aa:Ser,seq:gct)
     gene            complement(907..980)
                     /locus_tag="RD486_002837"
     tRNA            complement(907..980)
                     /locus_tag="RD486_002837"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(944..946),aa:Ile,seq:gat)
     gene            complement(994..1064)
                     /locus_tag="RD486_002838"
     tRNA            complement(994..1064)
                     /locus_tag="RD486_002838"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1030..1032),aa:Gly,seq:tcc)
     gene            complement(1066..1141)
                     /locus_tag="RD486_002839"
     tRNA            complement(1066..1141)
                     /locus_tag="RD486_002839"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1106..1108),aa:Asp,seq:gtc)
     gene            complement(1160..1233)
                     /locus_tag="RD486_002840"
     tRNA            complement(1160..1233)
                     /locus_tag="RD486_002840"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1197..1199),aa:Met,seq:cat)
     gene            complement(1246..1335)
                     /locus_tag="RD486_002841"
     tRNA            complement(1246..1335)
                     /locus_tag="RD486_002841"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1297..1299),aa:Ser,seq:tga)
     gene            complement(1359..1432)
                     /locus_tag="RD486_002842"
     tRNA            complement(1359..1432)
                     /locus_tag="RD486_002842"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1396..1398),aa:Ile,seq:cat)
     gene            complement(1446..1519)
                     /locus_tag="RD486_002843"
     tRNA            complement(1446..1519)
                     /locus_tag="RD486_002843"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1483..1485),aa:Met,seq:cat)
     gene            complement(1547..1619)
                     /locus_tag="RD486_002844"
     tRNA            complement(1547..1619)
                     /locus_tag="RD486_002844"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1584..1586),aa:Ala,seq:tgc)
     gene            complement(1639..1712)
                     /locus_tag="RD486_002845"
     tRNA            complement(1639..1712)
                     /locus_tag="RD486_002845"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1676..1678),aa:Pro,seq:tgg)
BASE COUNT          479 a          466 c          398 g          376 t
ORIGIN      
        1 ttagcacaat catccataaa gataactctg ctaagctttt taaaatcatt ctttcagata
       61 aaaagaaaaa gatactcaaa aagtatcttc catgacccgt acgggattcg aacccgtgtt
      121 accgccgtga aagggcggtg tcttaaccgc ttgaccaacg ggccaataaa ataaatgggc
      181 ctaaatggac tcgaaccatc gacctcacgc ttatcaggcg tgcgctctaa ccagctgagc
      241 tataggccca taaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga
      301 aggctgtggt tttaccacta aactacaccc gcataatggc gcgggacaga atcgaactgc
      361 cgacacatgg agcttcaatc cattgctcta ccaactgagc taccgagcca aacggttccg
      421 acgggaatcg aacccgcgat ctcctgcgtg acaggcaggc atgttaaccc ctacaccacg
      481 gaaccaatgt ttttagtttt taattgcggg agcaggattt gaacctacga ccttcgggtt
      541 atgagcccga cgagctacca gactgctcca tcccgcgata atatgaaaaa ggaggataag
      601 ggattcgaac ccttgcacgg ttttacccgc ctgacggttt tcaagaccgt tcccttcagc
      661 cggacttggg taatcctcca tgtaaaacta tattaaatta atgacccgta cgggattcga
      721 acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg gccaggtaaa
      781 acaaaatatt gaaacggaga aggagggatt tgaaccctcg cgccggtttc ccgacctaca
      841 cccttagcag gggcgcctct tcagccactt gagtacttcc ccaaaaccaa taagattttg
      901 tactaatggg cctaaatgga ctcgaaccat cgacctcacg cttatcaggc gtgcgctcta
      961 accagctgag ctataggccc ataaaaaact aaaagcgggt gacgagaatc gaactcgcga
     1021 caacagcttg gaaggctgtg gttttaccac taaactacac ccgcatggcg gttccgacgg
     1081 gaatcgaacc cgcgatctcc tgcgtgacag gcaggcatgt taacccctac accacggaac
     1141 cagtgttttt agtttttaat tgcgggagca ggatttgaac ctacgacctt cgggttatga
     1201 gcccgacgag ctaccagact gctccatccc gcgataatat gaaaaaggag gataagggat
     1261 tcgaaccctt gcacggtttt acccgcctga cggttttcaa gaccgttccc ttcagccgga
     1321 cttgggtaat cctccatatg aaacttacaa cgccacaatg gaccttgtag gactcgaacc
     1381 tacgaccgga cggttatgag ccgtctgctc taaccaactg agctaaaggt ccaggctctt
     1441 aaaaatcgcg gcggagggga tcgaaccccc gacctcccgg gtatgaaccg gacgctctag
     1501 ccagctgagc tacaccgcga aaaagatatt cattatttaa atgaaatgga gcctagcggg
     1561 atcgaaccgc tgacctcctg cgtgcaaagc aggcgctctc ccagctgagc taaggccccg
     1621 tgtttaaatt tataattatc gggaagacag gattcgaacc tgcgacccct tggtcccaaa
     1681 ccaagtgctc taccaagctg agctacttcc cgtttaatt
//
LOCUS       DAPBBV010000115         1681 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.123, whole genome shotgun sequence.
ACCESSION   DAPBBV010000115 DAPBBV010000000
VERSION     DAPBBV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1681
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.123"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            107..1276
                     /locus_tag="RD486_002846"
     CDS             107..1276
                     /locus_tag="RD486_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7664512.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          604 a          266 c          265 g          546 t
ORIGIN      
        1 aagatagcgt aaaatatttt gtgtaaatag aaatttaggg tagaaaaaaa agtccattct
       61 gtaaaattaa agttaccaca cagaaatttt ataggaggac tttctcatga ctaaatttac
      121 tatagaaatt atgcaaacac tactcaataa aggggattta gatgaattat ttcaggatca
      181 tttagagcga gcgattaatt cacttctaca agcagagcta actgcttttt tagattacga
      241 aaaatatgat cgaaatggat tcaattcagg aaattcccgt aacgggaatt attcacgtac
      301 atttaaaaca gaatatggcg agttgaattt aactattcct agagatcgga atggcgaatt
      361 ttctcaacaa acactaccag catataagcg aaccaatgat tcattagaaa cgaccattat
      421 ccaattattt caaaaaggca ttactatggc tgaaatctcc aaattaattg aaaaaatgta
      481 tggtcaccac tatacgccac aaacaatctc caacatgagt aaattggtgg ctgaagatgt
      541 tttagctttt aaagaaagaa cgttagaagc caattattcc gttatattta tggatgcgac
      601 gcatatccct gtgaagcgac agactgtttc gaaggaagca gtgtatatta cgattggtat
      661 tcgtttggat ggaaccaaag aagttcttgg gtttactatt gccccaactg agtctgctta
      721 tatttggaaa gaagttcttc aagatcttag aaaacgtggg ttagaagaag ttttattagt
      781 agtgacagac ggattaagct gtattgaaga aagtatccat agtgtgtatc cgaatgccca
      841 atttcaacaa tgttgtgtgc atgtatctag aaatatcgct cataaagttc gtgttcgagg
      901 tcgaaaagaa atttgtgagg atttcaaatt ggtttaccaa gcgaattcaa aagaagaggc
      961 attggatcac atcgacttta tgactaggaa atggaaaaag cagtatccaa gagtcgtcaa
     1021 tttactcttg aatcctgccc tattaacctt ttataatttc cctcacgcca tcagacgaac
     1081 aatttattcg acgaacctga ttgaaggctt taataagcag ctaaaacgat atactcgaag
     1141 aaaagaacaa ttccctaatg aagaatctct agagagattc ttcatttctc aatttaatca
     1201 atataaccaa aaatttttag gtagaattca caagggattt aaagaaattc aggatacatt
     1261 agagtcgatg atttaactgt aattaacaga atggattttc catttacaca taattcttga
     1321 cgctaccata atctaaataa ccatcatatt catctactac ttatataatt gagttttatt
     1381 aaacttttta agtttctatt ctatcaaata tttaaacaat ctctgcatcc gaaaagacta
     1441 cctcgtatag ttttactaac aatattttta ttagcgtgtt caaatcctga tttcttgtat
     1501 caattatttt ctgttcactt tcaataagaa aaaagtcttt acttccatgg ataataataa
     1561 gtctctattt ttcaataact attgcaaaat tatatcttaa ttaagaaaat atttttattt
     1621 taaagataaa aaattcttca tcctgcaata ctttatattc tatattgtaa ttattcagaa
     1681 t
//
LOCUS       DAPBBV010000116         1652 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.126, whole genome shotgun sequence.
ACCESSION   DAPBBV010000116 DAPBBV010000000
VERSION     DAPBBV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.126"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            78..193
                     /gene="rrf"
                     /locus_tag="RD486_002847"
     rRNA            78..193
                     /gene="rrf"
                     /locus_tag="RD486_002847"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            203..276
                     /locus_tag="RD486_002848"
     tRNA            203..276
                     /locus_tag="RD486_002848"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:237..239,aa:Asn,seq:gtt)
     gene            316..405
                     /locus_tag="RD486_002849"
     tRNA            316..405
                     /locus_tag="RD486_002849"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:350..352,aa:Ser,seq:gga)
     gene            420..491
                     /locus_tag="RD486_002850"
     tRNA            420..491
                     /locus_tag="RD486_002850"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:453..455,aa:Glu,seq:ttc)
     gene            507..579
                     /locus_tag="RD486_002851"
     tRNA            507..579
                     /locus_tag="RD486_002851"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:540..542,aa:Val,seq:tac)
     gene            589..661
                     /locus_tag="RD486_002852"
     tRNA            589..661
                     /locus_tag="RD486_002852"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:622..624,aa:Asp,seq:gtc)
     gene            697..772
                     /locus_tag="RD486_002853"
     tRNA            697..772
                     /locus_tag="RD486_002853"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:730..732,aa:Phe,seq:gaa)
     gene            774..854
                     /locus_tag="RD486_002854"
     tRNA            774..854
                     /locus_tag="RD486_002854"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:808..810,aa:Tyr,seq:gta)
     gene            861..934
                     /locus_tag="RD486_002855"
     tRNA            861..934
                     /locus_tag="RD486_002855"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:893..895,aa:Trp,seq:cca)
     gene            937..1009
                     /locus_tag="RD486_002856"
     tRNA            937..1009
                     /locus_tag="RD486_002856"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:970..972,aa:His,seq:gtg)
     gene            1021..1092
                     /locus_tag="RD486_002857"
     tRNA            1021..1092
                     /locus_tag="RD486_002857"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1053..1055,aa:Gln,seq:ttg)
     gene            1138..1208
                     /locus_tag="RD486_002858"
     tRNA            1138..1208
                     /locus_tag="RD486_002858"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1170..1172,aa:Cys,seq:gca)
     gene            1229..1313
                     /locus_tag="RD486_002859"
     tRNA            1229..1313
                     /locus_tag="RD486_002859"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1263..1265,aa:Leu,seq:caa)
     gene            1375..1447
                     /locus_tag="RD486_002860"
     tRNA            1375..1447
                     /locus_tag="RD486_002860"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1408..1410,aa:His,seq:gtg)
     gene            1457..1528
                     /locus_tag="RD486_002861"
     tRNA            1457..1528
                     /locus_tag="RD486_002861"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1489..1491,aa:Gln,seq:ttg)
     gene            1546..1630
                     /locus_tag="RD486_002862"
     tRNA            1546..1630
                     /locus_tag="RD486_002862"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1580..1582,aa:Leu,seq:caa)
BASE COUNT          388 a          375 c          431 g          458 t
ORIGIN      
        1 actcggaaaa aaacttatgt gacttcaaat ccagttttga gtgaacaaaa tttactcaat
       61 aaaagataac accacagtgt ggtggcgata gcgagaagga tacacctgta accatgccga
      121 acacagaagt taagcttctt agcgccgatt gtagtgaggg gttgcccctt gtgagagtag
      181 gacgtcgcca cgctgatgtt attccggcat agctcagttg gtagtagcgc atgactgtta
      241 atcatgatgt cgtaggttcg agtcctactg ccggagttct cattttgaga aagagtattg
      301 agcttctttc actctggaga gttgtccgag aggccgaagg agcatgattg gaaatcatgt
      361 agatggtgcc aaactgtctc aagggttcga atcccttact ctccgtagca aatttacctg
      421 gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg gttcgaatcc
      481 cgtacgggtc attttaattg aatgttggag gtttagctca gctgggagag catctgcctt
      541 acaagcagag ggtcagcggt tcgatcccgt taacctccat aatgaactgg ttccgtggtg
      601 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
      661 gtcgttcttg ttattcaatt aataatttta aaatatggcg cggtagctca gttggtagag
      721 caacggattg aagctccgtg tgtcggcagt tcgattctgt cccgcgccac catggaggag
      781 tagcgaagtg gctaaacgcg acggactgta aatccgttcc ttagggttca gtggttcgaa
      841 tccactctcc tccattttat aggggcatag tttaaaggta gaacagcggt ctccaaaacc
      901 gttagtgtgg gttcaattcc tgctgcccct gccatggcga atgtggcgaa gtggttaacg
      961 caccggattg tggctccggc attcgtgggt tcgattccca tcattcgccc tttttattct
     1021 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
     1081 cagctacccc agtttctata atttattctt tattttatag attgataata gtataatggc
     1141 ggtatagcca agtggtaagg cagaggtctg caaaaccttc atcaccggtt caaatccggt
     1201 taccgcctta gtactaataa atcaacttgc cggcgtggcg gaattggcag acgcgctgga
     1261 ctcaaaatcc agtgcccgtt gagggcgtgc cggttcgacc ccggccgccg gtattgacta
     1321 agatgtcttc atcttagttt tttattgaga aattaaataa catcttttat gatggcgaat
     1381 gtggcgaagt ggttaacgca ccggattgtg gctccggcat tcgtgggttc gattcccatc
     1441 attcgccctt tattcttggg gtatagccaa gcggtaaggc aagggacttt gactccctca
     1501 tgcgttggtt cgaatccagc taccccagtt attattttta aatttgccgg cgtggcggaa
     1561 ttggcagacg cgctggactc aaaatccagt gtccgttgag gacgtgccgc ttcgaccccg
     1621 gccgccggta taattatcaa tatagcaact tt
//
LOCUS       DAPBBV010000117         1652 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.127, whole genome shotgun sequence.
ACCESSION   DAPBBV010000117 DAPBBV010000000
VERSION     DAPBBV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.127"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            55..1602
                     /locus_tag="RD486_002863"
     CDS             55..1602
                     /locus_tag="RD486_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDT7664513.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
BASE COUNT          557 a          299 c          340 g          456 t
ORIGIN      
        1 gtttcttgtg gtattctgta acaaaatcag ttcgattcaa ggtggtgaaa aattttggaa
       61 actacagata cgttgcttca gttgcttcaa gaagcccata aaaccaatca agcacaacaa
      121 caaaccattc agaatcttac aactgaaatc caactattga atgaaaaggt caattattta
      181 accaacaaat tatttggacg ctctaaagag actctctttg aggaaacgaa tgggcaattg
      241 aatcttttta gtgatgaaga aatttctgta agtgttccag aagcagctgc caccattatt
      301 ccagtaaaag gacatcaacg agttgtagga acgaaagcag acaaaatcaa acacttacct
      361 ataacagaga aagaacatct ccttcctttg gaagaacaat tttgtgaaca ttgcggttca
      421 cagatgaaag atatcggacg gacaaaagta cgagaagaaa ttcgtttcca tcaggctatg
      481 ttggattgtc tcacccatta tcaacatacc tattgttgta aaagctgcga aaaagaagga
      541 ctttcttctt ttaaaaaagc gatcgttcct aaacctttga tttctaatag cttaggttcc
      601 aatagtttag tggcggaaac gatccggatg aaatttggtc agaaagttcc tgcctatcgg
      661 caagagaact attggaaaca aacacatggg ttggatattt cgagagataa tatcaccaat
      721 tggcatatta aagcagtgca aaacgcgtta gaccctttag gagaacgatt aagagtctat
      781 cttaatcaag aagagattct acacggggat gaaacaagtt atcgtgtgat tgaaagtgcc
      841 aaaacagata cctattactg gcagttttgt acaggaaaag acagtcagca tcccatcgtt
      901 tattatcacc acgacgaaag tcgtgctgga gatgttccga aaacttttct caaggagttt
      961 acagggtatt tacactgtga cggctatagc gggtataatg ccgtggaaag tgtacgactt
     1021 gtctattgtt tcgcgcatgt tcggcggaaa tttttcgaag caattccaaa aggaaagaaa
     1081 aacacggata ttcccgcagc tcaagcagtc aaacaattgg ataaatggtt tgtcctagaa
     1141 aagaaatgga aagacttttc tcctgagaag cgattaagct gtcggcaaca agaactgcgt
     1201 ccattattta ttgcttttta tgagtggatg gcaacgatag atcctgttgc aaaatccaag
     1261 ttggatgcag ccgttcaata tgcgtgtaaa ctacgaagtg gttttgaacc tatttttgaa
     1321 gatggtcgtt tagaactcac aaataatcgt gcggagcgaa atatcaaaga gctggtgata
     1381 ggacggaaaa attggttgca ttccacaagt cttgaaggag cacgaacttc aggaatcatt
     1441 ctgagtgtat ataaaacagc agaacttaac ggattgaatc ctgtaaagta tctagagttt
     1501 ctatttgata agataccaaa tcttcccgta ctttcagcag aaactttaga tcaactgttg
     1561 ccttggaaca aggatgtaca acaacatttt tctcgtaact aaaaacgcca aacattcccg
     1621 attctattct ataggtcggg ttatttgacg ta
//
LOCUS       DAPBBV010000118         1599 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.128, whole genome shotgun sequence.
ACCESSION   DAPBBV010000118 DAPBBV010000000
VERSION     DAPBBV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.128"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..105
                     /locus_tag="RD486_002864"
     CDS             <1..105
                     /locus_tag="RD486_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7664514.1"
                     /translation="MEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
     gene            156..452
                     /locus_tag="RD486_002865"
                     /pseudo
     CDS             156..452
                     /locus_tag="RD486_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337995.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            482..646
                     /locus_tag="RD486_002866"
     CDS             482..646
                     /locus_tag="RD486_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664515.1"
                     /translation="MKLTKIAVILAVIAGIILYFVLPANQFFLYFGIPAILIVNGVRI
                     FEQRKKCSST"
BASE COUNT          483 a          267 c          312 g          537 t
ORIGIN      
        1 atggaagcca tccgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt
       61 tcggtctgta ctgaaatcaa ggtattattg ggaatcccag cttaaatcat agataccgta
      121 agggatttta ttctttattt aaaactttgc aacagaacca tgctggttat agatgttaca
      181 aaatgagtta ttatgtaagt ccttctaaat gcaaacaatt ggctcgccaa actaataaac
      241 ttaataccgt ctcagctatt gcaaacttta ttggactatc tggattaaca ccggggatta
      301 tatcattagt tttcggatca gcagttagtg ctaataatgt atttgttaca gccgctagaa
      361 gaggaaaagg cgttcaatta aattatattg cccattttag taataccact acctataatt
      421 atagttctaa ccaaaattat gttataaaat aattaaaact ttaaactagg aggaatgctt
      481 tatgaaatta acaaaaattg ctgtaatttt agctgttatt gctggcatta ttttatattt
      541 tgtattgcct gctaatcaat tcttccttta ctttggaata cctgcgattt taatagtaaa
      601 tggcgtaaga atctttgaac aacgaaaaaa atgtagctct acctaatcgt tacaaaacaa
      661 caatttcacc ttcggtgaaa taagcgaaac tttacaaaaa gtggctagca aatgctagcc
      721 actttttgta ttgtagagcg tgaattttga gggggattca agggggagct tgcgcccctt
      781 tgacaagcgg ttatttgcac caaatacctc cgtatttggc tagcaatcct tctaaaaaat
      841 acacctatcg atcagagtca aaacaaatca attttcgagt gagcgaatcc gaatttgcaa
      901 agctgaagct ttgcaaatga gtgtgccggc ttccgtaaaa atacatatgg ctataatttg
      961 cgttttaagg cgttttaaac gttctggtat ataattatac caaaacaact ttaaaacgcc
     1021 ttagatctaa ttttagaggt cttatagaac attttagggt tgttagggct tgccctgacc
     1081 gcctgtaagg cgctttgaga acaagataag ggttttatac taagactgtc ttaaaacggc
     1141 ttaaacaaac gctcagaact tttcaaagga gttctttatg aactgttttt aagcaaagga
     1201 gcctttaggc gactgcgcag tataatgtga gagcgtagcg atcacacatt tttagtgacc
     1261 gtagggagcg agtttcccag tttagaaaaa ttcgcgaact tgtttgagga aaaaagcagg
     1321 agttttttag gcgggaaatt ttgcctcctc ttttataatc tctttttaaa cctcttttta
     1381 aacctcttta ccgtcggctg tatgcttact ctcccaaggt gtgcagaatc ttttgggggt
     1441 ctttttgtct gtttttaggg gtctttttgt ctgtttttgg gggtcttttt gtctgttttt
     1501 aggggtcttt aattaggggc ttgaccccta ttagaaagct ctttataatt ttgttaagta
     1561 gttaatcttg aaggaggatt ttatggcaaa tgaaattgt
//
LOCUS       DAPBBV010000119         1482 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.129, whole genome shotgun sequence.
ACCESSION   DAPBBV010000119 DAPBBV010000000
VERSION     DAPBBV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.129"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            367..921
                     /locus_tag="RD486_002867"
     CDS             367..921
                     /locus_tag="RD486_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7664516.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            1175..>1482
                     /locus_tag="RD486_002868"
     CDS             1175..>1482
                     /locus_tag="RD486_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664517.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     "
BASE COUNT          592 a          156 c          256 g          478 t
ORIGIN      
        1 atgaaaagtt tggtagcacg gttattcata tgctaattta tttcacttta tagtaagggg
       61 agttcttagt atattgttca aacttaaatt tcatataatt taattatgta aattagctat
      121 tctaagaact tctacggata actgcccgtc taaaatttaa ataagagctt agaatcttca
      181 tataagtaag gttaattttt ttgtacaaaa aagtcggaat attctgagtt actgaaatga
      241 tataaaatca taaactaaac cccttgattt tcttcacttt taacagagta tatatataag
      301 ttcatgatta tggtaaaata tatatataat catgaactca gaatattttt aagaagggaa
      361 acaatagtga gctataatgt acaaccgtta aggacaaatg aagagataca agattttcag
      421 ttttggctaa gaagaacaag taatccagaa agagatagtt ttttattttt gtttggaatc
      481 aataatgggt tacgtatgtc agatattata ggattaaaag ttggagacat acgaggtaaa
      541 agtaagccta ttattgttga acataaaaca ggtaagcgaa aaccgatttt tatagataat
      601 ttgagagaag agattttatt atatactgaa ggtaaagaag aaaatgattg gttatttcca
      661 agtcggcaac aaggtcgaca tataacaagg gatcgtgtct atcagatata tgcagatata
      721 gcagaaaaat taggaagaga tgatatagga acacatacat taagaaaaac ttttgggtat
      781 cactactaca agaaaactag agacattgct accttaatgt ttatttttaa tcatagctcg
      841 caagcaatta caaaaaggta cattggtata actgaagatg aaataggggc atcgttacgt
      901 ggttttaaat tgggaggcta attgagatat taggatatat tttttgtgta taatgaaaac
      961 ttagaaggtg agattaatga agataactga attttcggaa gtatttaaaa cgtttagtaa
     1021 catttacaat agaataccag agatagaaca aaatgttgta gttgataatg attattatat
     1081 agagaatgat tttaataaac caagaaaata tgacaaccta tacaatttta tacacaatag
     1141 aacaacaata aataacaaca gtaacactcg agttttgatt aattcagcat attttcatat
     1201 taaatattta aagaaatatg agtatgaaga agttgtatta gattatgggc taaatagaca
     1261 gtcattttta atttatgcaa taaataacgg aaatttgcca agcaataaaa agaacataat
     1321 tattgaaaca tatgcctatc tggagggggg atctaaaaaa ctaattaagt catgtaatat
     1381 agagtatcaa ttatcagtag gagaaattaa atgtgttttc gaagaagatt tagaacttga
     1441 cttaaaaaaa atttttgcca gcattcatga ttatataggt tt
//
LOCUS       DAPBBV010000120         1352 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.130, whole genome shotgun sequence.
ACCESSION   DAPBBV010000120 DAPBBV010000000
VERSION     DAPBBV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.130"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            306..848
                     /locus_tag="RD486_002869"
     CDS             306..848
                     /locus_tag="RD486_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664518.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            1004..>1352
                     /locus_tag="RD486_002870"
     CDS             1004..>1352
                     /locus_tag="RD486_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDT7664519.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          524 a          163 c          258 g          407 t
ORIGIN      
        1 aggcttacca gcgagataga gatcgacgat ttgttgtttg aattcttttg aataggttct
       61 tcgttgacgt cttggcatga aaaatcctcc agtgtgtttt ttattattct acacacctta
      121 ttttttctgt ctagtctagt gtagccgatt caagttcttc gtgttctctt agacataaaa
      181 attcctcctg gtatgttttc ttctagtcta cacaccttaa tttttctgtc tagttaattg
      241 tagcctatcc agtttggaaa aataaaaaat tatatttcat caacgtttca taaaaggtgt
      301 gtagaatgtt attgaaagta gctataaaat gctattgtgt aaaaaataaa ggaggaataa
      361 tttatgaaaa aatagtacca agaggagcat gcctattact tgcattatgt ttgagcttaa
      421 gcgcagttgg gtgtcaaaaa agtaatgaaa acaataaaat aaaagaagga caatccataa
      481 gttctgaaga ggaaggcatg tcaattaatg caaatggcaa aaatgaaact tttaagccat
      541 cagattatac attggaggca aagaaagaat atgtttatga atatttaggg cttaaattta
      601 aactctcaga caaatttaga aattatatag ctgataaaaa gatagcgatg ttagatgatc
      661 aaagtcctat agataaagaa ctaaagtatg ctattttgac atttgagaaa atgacagaag
      721 aacaaaagaa tgcagttata gaaaagatgg gcgatggata taaaaattgg caaaatgagc
      781 ttgaaagaat tgggactatt ggtatatttg aaaaaaatac atcagaagaa aaaaatctaa
      841 aattataaaa tgtgatactc atactaaaat aggagtttca agtgatggaa aatacgattg
      901 ctatttaagc acaaatagcg gagctgaaag taatcttctt gatgaattaa aaagaactga
      961 gattcaaatt atagataaaa aagaacgtcc taaaaatggt tttgtgctat cagaaaaaac
     1021 tgatttagaa aatacagaag catttaacaa agaatcggtt aaagatttac gtaaactacc
     1081 aacaaaggac ataaatggca aggattttac aagtaaagat tttgagaagt atgatcttac
     1141 tatggtaaat gtatttgcaa cttggtgtac agcttgtgta aaggaaattc ctgatttggt
     1201 tgaggttcag aatgaaatga aaagcaaggg tgtaaatatc gttggagttg ttacagatcc
     1261 tgttgatgat aacggtgaaa acaaggaagc aattgaaaag tcaaagttaa tacatgaaaa
     1321 gacaaaggct tcatatcctt tcttaatgcc ag
//
LOCUS       DAPBBV010000121         1339 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.131, whole genome shotgun sequence.
ACCESSION   DAPBBV010000121 DAPBBV010000000
VERSION     DAPBBV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.131"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(69..1208)
                     /locus_tag="RD486_002871"
     CDS             complement(69..1208)
                     /locus_tag="RD486_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HDT7664520.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT          350 a          289 c          249 g          451 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtttatta
       61 aaaaaatctt acgctaagta ggataaaata attccttgat atttttcgat catatccaaa
      121 taattatcga tttcaacata ctcatctact tgatgaggca aagtaacgac accaggccca
      181 aagacgacaa agtcgaagga atggttagct ttcgtaaatt cggctgcatc cgttgttgct
      241 gccgctccaa ctaaaggtaa tggctggctg aattgttgct gaatgcaatg aatcaaagga
      301 gaatctggat cagctttgac aggtattttg ttgtaatcga tcatcaattc caaatgatag
      361 tctgtctctt gattcaattc attgacgatt gattgcagca atgcaatgat tttatcattt
      421 gggtattctg gaatcgatcg aatgttccct tggagctgcg catggcttgg gatgctgttg
      481 acttgattcc cgccactgat caatgtaaca ttatggattg tttttcctag gacaggattc
      541 tcgattgttt cagcgaggtg attcatttca gcatttgctt tcgtaatgaa ttcatttagg
      601 tgattgattg cattataacc ttggtctggc atagagctat gcgcttcttt tccgtgcgag
      661 gtgactgtat agttgattga tcccatgtgc gtatacatca aactgtaatt ggttggctct
      721 ccgatgatca aggcatctaa gtcatctaca tagcctgctt tcgtgagctg ttccccacct
      781 agttcaccca cttcttctcc gacagtggct aataatttga ctgttccgtt aaatggtttt
      841 cctgactctt tcagttcgat catggcaatc accattgctg ccaagccact cttcatatct
      901 gtagcaccac gtccgtacaa acggttccca tggatttctg ctgcaaaggg tgcataggtc
      961 caagacgatt catcaccagc cgccacgaca tccatatgcc cagataggcc taacactttt
     1021 cctgattggc ccttttggta acgagcaatc aaattatctc taccatctct gtaagaaaca
     1081 atctctcctg ttatgtcatg ctttgccaaa agcttattca aataggctgc tacttcacct
     1141 tcgtttccat tcactgattt aattcggata atctcttgta aaatcgcgat tttttcttct
     1201 tttttcatct aatcctctcc cttgccattt ctttttattg tatttgagtg tgctcgaatt
     1261 ttcaaatagg agcaaccaaa gtaaaaatga agaaagagag ccactttatg aaaaatatgc
     1321 tgctacttcc ctcctattt
//
LOCUS       DAPBBV010000122         1329 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.132, whole genome shotgun sequence.
ACCESSION   DAPBBV010000122 DAPBBV010000000
VERSION     DAPBBV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.132"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            66..>1329
                     /locus_tag="RD486_002872"
     CDS             66..>1329
                     /locus_tag="RD486_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7664521.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIM"
BASE COUNT          416 a          264 c          256 g          393 t
ORIGIN      
        1 tatagaaaag acaccctgaa atcctttaga attaatttgg ctaccaattc ataggaggat
       61 tcaagatgtc tcatactcag cttatcaaag ataccctaaa tattctagac ctaaatatct
      121 atttcgagga aaattgttta actaaagaaa aatacaaagg gcaaatttgc ttgatttaca
      181 aaggaactct tctgtacaag ccagaagagt gttcccattg tctttgtgtc gtcccctcta
      241 ggatcattcg ttgggggacg acaaccgttc ggttgttact gaatgatgtg tctgagtatc
      301 gcacttatct ggagctgaag aaacaacgat ttaaatgtaa gtcttgccaa agaacattcg
      361 tagcggatac ctctgttgct gaaaaacact gtttcattag tcaaaaagtt cgttggtctg
      421 tcattgctcg cttaaaagag aatacttcca tgacggaaat cgctcgtcag aaaaatattt
      481 ccacttcttc ggtctatcgt gtcatgaagc gattctaccg cccattgaat cctttcaaac
      541 agactttgcc aaaggtctta tgctttgatg aattcaaatc ggttcgaagt gttgccagtg
      601 caatgagttt tatcatgatg gacggacaaa gccatgcatt attggatatt gtcgaaaatc
      661 gacgcttgcc ttatttagaa cgctattttt ctcggttttc attagcgact cgtgaagccg
      721 ttcaattgat tgttattgat atgtatgcgc cttatgtttc gttggtgaaa aagcttttcc
      781 cgaatgctca gttgatcatc gatcgtttcc acatcgtcca acatattggc agaactttct
      841 tgaatcatcg agtgaaagaa accacggtac gacttaaagg aaattcccac tctcaacgag
      901 ggttagggaa aaaattgaag cgctattgga aactcctaca aaaagaagaa gcaaagttaa
      961 actatgaaaa acgggtttgg cgtgccagtt ttaaagatta tttgactgaa agtgagattg
     1021 ccgatcgact gttagctgct tgtcccaact tacgccaagg ctatcagtta taccaagaca
     1081 ttctttatgc ggtaaagaaa agagatcagt cactatttga ggattgttta actagagaca
     1141 ttagcggtct gccagaaacc tatacaacca ctttacgaac gtttaaaaag tttctgccac
     1201 agatccaaaa tgcgcttcac tacagctatt caaacggacc attggaatgc ttaaacaacc
     1261 acatcaaagt attaaaacgc aatgcgtacg gctttcgcaa cttttacaat ttcaaactac
     1321 gaattatga
//
LOCUS       DAPBBV010000123         1320 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.133, whole genome shotgun sequence.
ACCESSION   DAPBBV010000123 DAPBBV010000000
VERSION     DAPBBV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.133"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            82..>1320
                     /locus_tag="RD486_002873"
     CDS             82..>1320
                     /locus_tag="RD486_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HDT7664522.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKS"
BASE COUNT          448 a          258 c          251 g          363 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
//
LOCUS       DAPBBV010000124         1304 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.134, whole genome shotgun sequence.
ACCESSION   DAPBBV010000124 DAPBBV010000000
VERSION     DAPBBV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.134"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            139..>1304
                     /locus_tag="RD486_002874"
     CDS             139..>1304
                     /locus_tag="RD486_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664523.1"
                     /translation="MELLEKAYSSTELIDSYEYEDLKYIKDQRNYSAHPVVTYNGNTW
                     ELRDITKETCQDVIRKSYEIIFLKNPILGKKVTIEIIQYASRIHAMSVTPEEFHSALK
                     NSYLNKLSEKAKENLCKTAFKFVFQLSYGNEEADRDRESTFRLLNALIFDNKEFYLNI
                     LKKEIAKYRFTAESREEINKSLGENQQITYTKGFFLLTFIATHPELQHDFSDETIQNL
                     QISINDFKPKQQVLTEIEYYYRLRSLAVLGNNNEELQNHLNSLVDPILQQKMRVSSLP
                     SSTLETIYNQYLYFGEKEMFIDFMIEHLTDASSFRLADKDMEVLPWIYNKLNQEQFNK
                     LLYNLNGNNQFYKNSNFPPFISNLLDFYNQKFQVNLRKHYSGLLYPNAVTMDQG"
BASE COUNT          523 a          192 c          192 g          397 t
ORIGIN      
        1 aattacagtg cgcttatttt agatttaatt gataaattat ctgatttagc aaatatttac
       61 gaggataata cttctaagaa aattttagaa gatatagcta gactaagaaa aagtgatcca
      121 aactctccaa aatgggaaat ggaactacta gaaaaagctt atagttcaac tgagctaatt
      181 gatagctatg aatatgagga tttaaaatat attaaggatc aaagaaatta ttcagctcat
      241 cctgtagtca cttacaacgg taatacttgg gaattaagag atataacaaa agaaacttgt
      301 caggatgtta tacggaagtc ctatgaaatt atattcctaa aaaatccaat attaggaaaa
      361 aaagtaacga tcgaaattat acaatatgca agtcgcatac atgctatgtc tgttacacct
      421 gaagaatttc actctgcact aaaaaatagc tatctaaata aactaagcga aaaagccaaa
      481 gaaaacctat gtaagacagc ctttaagttt gtttttcaat tatcttatgg aaatgaggaa
      541 gcagatagag atagggaaag tactttcaga ctacttaatg ccctaatttt tgataataaa
      601 gaattctatt taaatattct aaaaaaagaa attgcaaagt ataggttcac agctgaatca
      661 agagaggaaa ttaataaatc acttggtgaa aatcaacaga tcacgtatac aaaagggttc
      721 tttttactta cttttatagc tacccatcca gaattacaac atgatttttc agacgagaca
      781 attcaaaatt tacaaatatc aataaatgat tttaaaccga aacaacaagt actaacagaa
      841 atagaatatt actaccgttt acgttccctt gcagttctag gaaacaacaa tgaagaatta
      901 caaaatcact taaatagtct agttgatcct atactccagc aaaaaatgag agtttcttcg
      961 ctaccatctt caacattaga aacaatatat aatcaatatt tatattttgg tgaaaaagag
     1021 atgttcatag attttatgat cgaacatctt accgatgcta gttcattcag gttagcagat
     1081 aaggatatgg aagtattacc atggatttac aataaattaa atcaggagca atttaacaaa
     1141 ttactataca acctaaatgg aaataatcaa ttttacaaaa acagtaattt tccgcctttt
     1201 atttctaatc tgttagactt ttataatcag aaattccaag tgaatttacg taaacattat
     1261 agtgggcttc tatatccaaa tgcagtgact atggatcagg gttt
//
LOCUS       DAPBBV010000125         1283 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.135, whole genome shotgun sequence.
ACCESSION   DAPBBV010000125 DAPBBV010000000
VERSION     DAPBBV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.135"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..964)
                     /gene="tet(S)"
                     /locus_tag="RD486_002875"
     CDS             complement(<1..964)
                     /gene="tet(S)"
                     /locus_tag="RD486_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HDT7664524.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIIL"
     gene            complement(965..1018)
                     /locus_tag="RD486_002876"
                     /pseudo
     CDS             complement(965..1018)
                     /locus_tag="RD486_002876"
                     /inference="COORDINATES: protein motif:HMM:NF019687.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          404 a          233 c          174 g          472 t
ORIGIN      
        1 ttaaaataat aatctcacca ggctctgcct tatctatctg gcgtaattct ccatttattg
       61 aagtatacat ttctgtaact tttatttttt ccttttctga tatattgact gagtctcgca
      121 aatgtagcgt tccactataa agacgtacat agacaagccg ttgaccatca tctgaatatt
      181 ctactttaaa aacatttcca caaagtttat ctgaattgag ttgtgtgggt gaaaataatt
      241 tgctagtaat tacctctata agttgtttaa ttccaatatt attctttgca cttccgtgat
      301 aaacaggata taaggagcaa ctttgaattc tttcgttttc ctccttttca agttctgcaa
      361 tattcaatgt tttcccaatg gtatattttt ctaataaata atcatttccc acaattactg
      421 tctcccattg ttctggttca gtataatcta ttacataagg tttcaaattt agattcacag
      481 tctgcttaat tatgatgtcg tcagaaagtt tgtccttaat atcttgataa acatctggca
      541 aatttattcc attttgatca attttgttaa taaaaaatat tataggtatg ttcatctttc
      601 taagtgcatg gaatagtata cgagtttgtg actgtactcc atcttttgca gagattagca
      661 aaatagctcc atccaaaaca gataatgaac ggtatacatc tgccaaaaaa tccatgtgtc
      721 caggagtatc tacaatattt actttaacat tttcccgttg aaaagatgtt attgcggtct
      781 gaatagtaat acctctctgg cgttccaaaa acatagtatc cgttttcgtt gtaccgctat
      841 ctacacttcc taactcttta attgctccgc tactgtatag taagctttct gtcaaagtag
      901 tttttcctgc atcaacatgt gctaagatac cgatattaat aattttcaat tttatttcct
      961 ccattcaaaa gctcaaaaag cagaaaaaat cccagtgata aatactctta tcactgggat
     1021 tttaatacaa aaatagctgt atactacaca ctgatagcca cagatgcttt atgataaaat
     1081 gataaaagta ttcttaaact gggcacaaaa aaccagtcct tattttaaat aaggatgctt
     1141 aattaattat tcccgctatc taattgacag tttatttaag aataccttgc cgcattttta
     1201 ttatctcctt ttgaatgtta tcttaattct atcatatgat agaatgcttg taaagccaac
     1261 catatttttt gaacgaaagg gaa
//
LOCUS       DAPBBV010000126         1241 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.136, whole genome shotgun sequence.
ACCESSION   DAPBBV010000126 DAPBBV010000000
VERSION     DAPBBV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.136"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            40..1212
                     /locus_tag="RD486_002877"
     CDS             40..1212
                     /locus_tag="RD486_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HDT7664525.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          460 a          228 c          221 g          332 t
ORIGIN      
        1 tgtttttaac gacaaaaaca tacccaggag gacttttaca tgacccaagt acattttaca
       61 ctgaaaagcg aagagattca aagcattatt gaatattctg taaaggatga cgtttctaaa
      121 aatattttaa caacggtatt taatcaacta atggaaaatc aacgaacaga atatattcaa
      181 gcaaaagaat atgaacgaac agaaaaccga caaagtcaac gaaatggcta ttatgagcgc
      241 agctttacga cacgtgtagg cacgctagaa ttaaaagtac ccagaacacg tgatggccat
      301 ttttcaccca cagtgtttga acgttatcaa cgaaacgaaa aagccctcat ggcttcaatg
      361 ttggaaatgt atgtatcagg cgtttcaact cgtaaagtat caaaaattgt ggaagaactt
      421 tgtggtaaat ccgtctctaa gtccttcgtt tctagcttaa cagaacagct agaacctatg
      481 gttaacgagt ggcagaatcg tttattatca gaaaaaaatt atccttactt aatgaccgat
      541 gtactctata taaaagtacg agaagaaaat cgagtactct caaaaagctg tcatatagcg
      601 attggaataa ccaaagatgg cgaccgtgaa attatcggct tcatgattca aagtggcgaa
      661 agcgaagaga cctggacaac attttttgaa tacctaaaag aacgcggttt acaaggtacg
      721 gaactcgtta tttctgatgc gcacaaagga ttagtctctg ccattagaaa atccttcacc
      781 aacgtaagtt ggcaaagatg ccaagttcac ttcctaagaa atatctttac caccattcct
      841 aaaaaaaatt caaaatcttt cagagaagct gttaaaggaa tttttaagtt cacagatatt
      901 aacttagcgc gtgaggctaa aaatcgattg attcatgatt atatcgatca accaaaatat
      961 tcaaaagctt gcgcatcatt ggatgatgga ttcgaagacg cctttcaata taccgtacaa
     1021 ggaaattccc acaatcgact aaagagtacc aatctaattg aacgactgaa tcaagaagta
     1081 cgcagaagag aaaagattat tcgcatcttc cccaatcaaa catcagccaa tcgcttaatt
     1141 ggagccgttc ttatggacct acatgatgaa tggatttatt cttcaagaaa atacatcaat
     1201 tttgataagt agaaatggta aaaacattgt atagcatttt a
//
LOCUS       DAPBBV010000127         1194 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.137, whole genome shotgun sequence.
ACCESSION   DAPBBV010000127 DAPBBV010000000
VERSION     DAPBBV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.137"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..1076
                     /locus_tag="RD486_002878"
     CDS             <1..1076
                     /locus_tag="RD486_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDT7664526.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tctt
//
LOCUS       DAPBBV010000128         1191 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.138, whole genome shotgun sequence.
ACCESSION   DAPBBV010000128 DAPBBV010000000
VERSION     DAPBBV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.138"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            82..>1191
                     /locus_tag="RD486_002879"
     CDS             82..>1191
                     /locus_tag="RD486_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HDT7664527.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREK"
BASE COUNT          393 a          221 c          233 g          344 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa g
//
LOCUS       DAPBBV010000129         1188 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.139, whole genome shotgun sequence.
ACCESSION   DAPBBV010000129 DAPBBV010000000
VERSION     DAPBBV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.139"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            141..398
                     /locus_tag="RD486_002880"
     CDS             141..398
                     /locus_tag="RD486_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664528.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="RD486_002881"
     CDS             complement(630..1061)
                     /locus_tag="RD486_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HDT7664529.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DAPBBV010000130         1092 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.140, whole genome shotgun sequence.
ACCESSION   DAPBBV010000130 DAPBBV010000000
VERSION     DAPBBV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.140"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="RD486_002882"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="RD486_002882"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDT7664530.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          136 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta ac
//
LOCUS       DAPBBV010000131         1061 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.141, whole genome shotgun sequence.
ACCESSION   DAPBBV010000131 DAPBBV010000000
VERSION     DAPBBV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.141"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(36..992)
                     /locus_tag="RD486_002883"
     CDS             complement(36..992)
                     /locus_tag="RD486_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664531.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DAPBBV010000132          836 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.142, whole genome shotgun sequence.
ACCESSION   DAPBBV010000132 DAPBBV010000000
VERSION     DAPBBV010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.142"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..>836)
                     /locus_tag="RD486_002884"
     rRNA            complement(<1..>836)
                     /locus_tag="RD486_002884"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          183 a          261 c          188 g          204 t
ORIGIN      
        1 tctctcaggg atcttacttt cttaaagaaa tgggaaatct catcttgagg tgggcttcac
       61 acttagatgc tttcagcgtt tatcccttcc ctacatagct acccagcaat gcccttggca
      121 gaacaactgg tacaccagcg gtaagtccat cccggtcctc tcgtactaag gacagctcct
      181 ctcaaatttc caacgcccgc gacggatagg gaccgaactg tctcacgacg ttctgaaccc
      241 agctcgcgtg ccgctttaat gggcgaacag cccaaccctt gggaccgact acagccccag
      301 gatgcgacga gccgacatcg aggtgccaaa cctccccgtc gatgtggact cttgggggag
      361 ataagcctgt tatccccagg gtagctttta tccgttgagc gatggccctt ccatgcggaa
      421 ccaccggatc actaagcccg actttcgtcc ctgctcgact tgttggtctc gcagtcaagc
      481 tcccttctgc ctttacactc ttcgaatgat ttccaaccat tctgagggaa cctttgggcg
      541 cctccgttac cttttaggag gcgaccgccc cagtcaaact gcccatctga cactgtctcc
      601 caccacgatt agtggtgcgg gttagagtgg ccataacgca ggggtagtat cccaccagcg
      661 cctccatcga aactagcgtt ccgatttcta cggctcctac ctatcctgta catgcggtac
      721 agacactcaa tatcaaacta cagtaaagct ccatggggtc tttccgtcct gtcgcgggta
      781 acctgcatct tcacaggtac taaaatttca ccgagtctct cgttgagaca gtgccc
//
LOCUS       DAPBBV010000133          811 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.143, whole genome shotgun sequence.
ACCESSION   DAPBBV010000133 DAPBBV010000000
VERSION     DAPBBV010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.143"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..672
                     /locus_tag="RD486_002885"
     CDS             <1..672
                     /locus_tag="RD486_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7664532.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          298 a          126 c          152 g          235 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaac cgtcaggttt a
//
LOCUS       DAPBBV010000134          763 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.144, whole genome shotgun sequence.
ACCESSION   DAPBBV010000134 DAPBBV010000000
VERSION     DAPBBV010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.144"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(237..716)
                     /locus_tag="RD486_002886"
     CDS             complement(237..716)
                     /locus_tag="RD486_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664533.1"
                     /translation="MCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNSL
                     DVEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKCFESAVVKFPQFKLNP
                     AASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          260 a          102 c           85 g          316 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttacctttgt aaaaatattc gattgaatat tctatttggc acgactcact tggcagtata
      541 tgtatgtcaa tatttttcat ctgtttcata ggtatttcaa catctaaact attaaaaaca
      601 tataattccc tgtaattatt tacatctaac tctactaaat ttatctttgg aacaatagat
      661 cctccaccca ttccaccata ataaaaaaaa tcttgttctc tatcaaaata gcacatatta
      721 agctcagttt gtttatcatc ctcaataatt ttataaatca aac
//
LOCUS       DAPBBV010000135          706 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.145, whole genome shotgun sequence.
ACCESSION   DAPBBV010000135 DAPBBV010000000
VERSION     DAPBBV010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.145"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..436)
                     /locus_tag="RD486_002887"
     CDS             complement(<1..436)
                     /locus_tag="RD486_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664534.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHF"
BASE COUNT          231 a          133 c          108 g          234 t
ORIGIN      
        1 caaagtgaat aaacgtcaat aaaaaatcct tcactccttt tgttgttctt ccagattgtt
       61 caatttgttt tattaaagtc gctagaattg catttacaac aattaaatcg aataggcttt
      121 tgaaaagttt tcctgctgtt aatttttgcc tggtaaattg catgactaat tgagtaaaaa
      181 tagacaatag catgacaaaa atcaacgtca ttagcactgt aaaaatgtct gatgctgcaa
      241 tcctattggg atcatttatc aagtaataag ccgttccaaa tactccaatc gagtaaacgg
      301 ttaaatcaag aataagtcgt gccccgtaac tacaaagttt tcctaatggc cataattgca
      361 atacccaaaa tttctttcgt ttgctatttc ttttcagagg aagccaggtg tgttcaatcc
      421 agtcgtccga tttcatttcg atttcttccc taaattcttt cctttaacgt tttcctttgc
      481 tactttagca gcgataggtt gctcaatgaa ccaatttttt aagtacgccg attgtaaaat
      541 taagctagac aactaaaaaa gtcatttgtg ctacactcaa aatagttccg tccaaagaat
      601 tataaggagt gagtacaaat gacctatacc catcttacaa cggatgaact tgtaatgata
      661 gagtcttatt tcaaaataaa tcaatctgtt gcgaaaactg cgcatt
//
LOCUS       DAPBBV010000136          697 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.146, whole genome shotgun sequence.
ACCESSION   DAPBBV010000136 DAPBBV010000000
VERSION     DAPBBV010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.146"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(54..629)
                     /locus_tag="RD486_002888"
     CDS             complement(54..629)
                     /locus_tag="RD486_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7664535.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          230 a          151 c          125 g          191 t
ORIGIN      
        1 aatgaaaaaa cagagccaga ttagcattat tttgctaatc cagctctgtt tattcagcct
       61 atttttcttt ttgaatatat caagcgttgg ggcaacatag tgatgactaa tgaaacaacg
      121 acgatagaca acaagcgatc aaggtagtct gtacccgcct gtaccaagat cacacttgtt
      181 gtctgactta aacctaaccc atgtaatagc tgaacgatca tactggatcc tgaggaggtg
      241 atcccgccaa ataactgaac ggtaatgatc gaagaaacga tcgttccagg taccgacaaa
      301 atcaaagcga gtaataacag tttcaagctg tttttatctt tgccgagata tcttggcaaa
      361 atcaatccag caagcaagcc tgtgagaatt tggattggcg aataatacag agaaaaaata
      421 tctgtagtca ctccacttaa aataccgctg gacaatcctg tcagcattcc aggtacaggc
      481 ccaagcaatg caccagcaaa aatcgttccg atagaatcga gatagattgg caaacgaagc
      541 cataaagcaa tcgttcctcc aatataattg atcccaatac acaaagccat cactgtaagt
      601 acgcgagttg ccattttgtt tttattcatt ttgttagccc atctttaacc tttccaaatc
      661 tttcataatc gtttcttctt gtgcatttaa aagaacg
//
LOCUS       DAPBBV010000137          687 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.147, whole genome shotgun sequence.
ACCESSION   DAPBBV010000137 DAPBBV010000000
VERSION     DAPBBV010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.147"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>687
                     /locus_tag="RD486_002889"
     rRNA            <1..>687
                     /locus_tag="RD486_002889"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          216 a          135 c          199 g          137 t
ORIGIN      
        1 ggagccgatg aaggacggga ctaacaccga tatgctttgg ggagctgtac gtaagctatg
       61 atccagagat ttccgaatgg gggaacccaa catctttaat aggatgttac gattgtgtga
      121 atacatagca cattcgaggt agacgcagag aactgaaaca tctaagtacc tgcaggaaga
      181 gaaagaaaat tcgattccct gagtagcggc gagcgaaacg ggaaaagccc aaaccagcaa
      241 gcttgcttgt tggggttgta ggactccaat atggtagttc tttcagatag tcgaatgact
      301 tggaaaagtc agtcaaagag ggtaaaaacc ccgtagacga aatgtggaag acacctagga
      361 ggatcctgag tacggcggaa cacgagaaat tccgtcggaa tccgggagga ccatctccca
      421 aggctaaata ctccctagtg accgatagtg aaccagtacc gtgagggaaa ggtgaaaagc
      481 accccggaag gggagtgaaa tagaacctga aaccgtgtgc ctacaacaag tcaaagcccg
      541 ttaatgggtg atggcgtgcc ttttgtagaa tgaaccggcg agttacgatt gcatgcgagg
      601 ttaagttgaa gagacggagc cgcagcgaaa gcgagtctga atagggcgtt tgagtatgta
      661 gtcgtagacc cgaaaccatg tgatcta
//
LOCUS       DAPBBV010000138          670 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.148, whole genome shotgun sequence.
ACCESSION   DAPBBV010000138 DAPBBV010000000
VERSION     DAPBBV010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.148"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..639
                     /locus_tag="RD486_002890"
     CDS             <1..639
                     /locus_tag="RD486_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HDT7664536.1"
                     /translation="IAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRGVQEVLL
                     FITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAVYQANSK
                     EEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIESFNKQI
                     KRYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          245 a          121 c          114 g          190 t
ORIGIN      
        1 attgccattg gtatacgaga agacggcact aaagaagtac tgagttatgc gattgctcca
       61 actgaatcaa catacgtttg gaatgagctg ctacaggata ttaactccag aggagttcaa
      121 gaagtcttgc tttttattac ggacggctta aaaggcatga aagatactat ccatcaaatt
      181 tatcctaaag caaaatatca gcattgttgt atccatgtat ctcgtaacat cgctcataaa
      241 gtacgtgtca aagaccgaaa agaaatctgt gatgacttta aggctgttta tcaagctaac
      301 tcaaaagaag aagcgaatac cttcttatcc ggcatgattg agaaatggaa gaaaaactat
      361 cctaaagtga cgcagtcact catagaaaac caagacttat taacttttta tgattttcca
      421 cctagcattc gtagaaccat ttactcaacc aatctaatcg agtctttcaa taagcaaatt
      481 aaaagataca gccgtagaaa agagcagttt caaaatgaag aatcactaga acgctttcta
      541 gtcagcattt ttgatacata caatcaaaaa tttctaaaca gaagccataa aggttttcaa
      601 caggtaaccg atacattagt ttcaatgttt actgagtaac taattatttt gcaggaggac
      661 aatttattta
//
LOCUS       DAPBBV010000139          643 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.149, whole genome shotgun sequence.
ACCESSION   DAPBBV010000139 DAPBBV010000000
VERSION     DAPBBV010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.149"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(26..379)
                     /gene="tnpB"
                     /locus_tag="RD486_002891"
     CDS             complement(26..379)
                     /gene="tnpB"
                     /locus_tag="RD486_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDT7664537.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(369..563)
                     /locus_tag="RD486_002892"
     CDS             complement(369..563)
                     /locus_tag="RD486_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664538.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          183 a          137 c          111 g          212 t
ORIGIN      
        1 acattttttg tgttaacccc ccagcttaaa aaactccttt ttttcctggc aaaatagctc
       61 gaggttgatc gatacttaat ccttctaaca accatcgaac ctgttggttc gttaaggttc
      121 gaacttcgtc tttcgtccga ggccatttta acttgccgtt ttctatccgc ttataacaga
      181 gaagaaaacc atcaccgtcc caatagagaa gtttgaaacg gtcttgacgg ttcccgcaaa
      241 ataaaaaaac ggcatcttcg taaagctcga gttgatactc ttgttgaata agactggcaa
      301 gaccatcaat tccttttcgc aaatctgttt ttccgcacac aatataaata tgtttggttt
      361 gaagtaaatc ataaagcatt ggacaacagt tctttcaaaa tagcttgaag aatataattg
      421 ttaataccgt tatagatcaa aacttcagaa ccattctctc ttttgatgcg catcgctaac
      481 ttggcagccg cgggtttacc tttttctggt gcactctttt cgtttcctaa ttggacagga
      541 acaatctcat ttaatttata catagaaaac ctccagactt cttgatagct caagtatatc
      601 ttgaggtgca tttgttagta aggtactgtt ctatggggcg ctt
//
LOCUS       DAPBBV010000140          641 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.150, whole genome shotgun sequence.
ACCESSION   DAPBBV010000140 DAPBBV010000000
VERSION     DAPBBV010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..641
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.150"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>641
                     /locus_tag="RD486_002893"
     CDS             <1..>641
                     /locus_tag="RD486_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HDT7664539.1"
                     /translation="FPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSP
                     LCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVK
                     VLETLSEEANLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQ
                     RKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL"
BASE COUNT          224 a          118 c          111 g          188 t
ORIGIN      
        1 actttcctag taggagtcga ttcactcgct taagttcaaa cttagcttac actatcaaga
       61 ttattcgata ctttttcatc aagaagctca ccaaaggtga actagtcgga attatagata
      121 gttttcctag tccattatgt aaaccagtta gaaatagaca agcaaaacta ttgaatcaaa
      181 tagccaaagt tggctataac tcaacaaaaa aatcttattt ttatggtctt aaaattcata
      241 tgatcgttac taagactggc tttccgatta cttactcaat cacgaatcca ggtgtccatg
      301 acgtgaaagt gttagagact ttatcggaag aagcgaatct tcccaatatc ctaggggaca
      361 aaggatatat tagccataaa atccatgaaa agcttgccct taagggcatt actatatccg
      421 ttccgccacg taaaaacatg gataaatcag aaaaactaga ccacagctta cttggaaaac
      481 aaagaaaaac agttgagact gttttttctt ccttagaaaa attaggttgt caaaatttca
      541 actcacgttc tgttaaaggg ctagagagta gatttgaaag catattactg gcttacagtg
      601 ttctattaag tcgagcacaa cgacgttttg aaggaacttt g
//
LOCUS       DAPBBV010000141          636 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.151, whole genome shotgun sequence.
ACCESSION   DAPBBV010000141 DAPBBV010000000
VERSION     DAPBBV010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.151"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..>636)
                     /locus_tag="RD486_002894"
     rRNA            complement(<1..>636)
                     /locus_tag="RD486_002894"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          128 a          209 c          134 g          165 t
ORIGIN      
        1 ccaacactta gcactcatcg tttacggcgt ggactaccag ggtatctaat cctgtttgct
       61 ccccacgctt tcgagcctca gcgtcagtta cagaccagag agccgccttc gccactggtg
      121 ttcctccata tatctacgca tttcaccgct acacatggaa ttccactctc ctcttctgca
      181 ctcaagtctc ccagtttcca atgaccctcc ccggttgagc cgggggcttt cacatcagac
      241 ttaagaaacc gcctgcgctc gctttacgcc caataaatcc ggacaacgct tgccacctac
      301 gtattaccgc ggctgctggc acgtagttag ccgtggcttt ctggttagat accgtcaagg
      361 gatgaacagt tactctcatc cttgttcttc tctaacaaca gagttttacg atccgaaaac
      421 cttcttcact cacgcggcgt tgctcggtca gactttcgtc cattgccgaa gattccctac
      481 tgctgcctcc cgtaggagtt tgggccgtgt ctcagtccca atgtggccga tcaccctctc
      541 aggtcggcta tgcatcgtgg ccttggtgag ccgttacctc accaactagc taatgcaccg
      601 cgggtccatc catcagcgac acccgaaagc gccttt
//
LOCUS       DAPBBV010000142          617 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.152, whole genome shotgun sequence.
ACCESSION   DAPBBV010000142 DAPBBV010000000
VERSION     DAPBBV010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.152"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            48..617
                     /locus_tag="RD486_002895"
                     /pseudo
     CDS             48..617
                     /locus_tag="RD486_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          253 a          102 c          117 g          145 t
ORIGIN      
        1 aaattaaggt gtgtagacta gaagaaaaca taccaggagg aatttttatg tctaagagaa
       61 cacgaagaac tttttcacaa gaattcaagc aacaaatcgt caatctttac ttagctggaa
      121 agccacgtgt agaaatcatt cgagaatatg aactaacggc ttcagcattt gacaaatggg
      181 taaagcaatc taaaacgagt ggttcattca aagaaaaaga taatcttacg cctgaacaaa
      241 aagaattgtt agaactacgt aaaagaaacc agcaattaga aatggaaaat gatattttaa
      301 agcaagcagc gctgatattc ggacgaagag acaagtaatc gatgcgaata agcatcttta
      361 ccctatatca gcgatgtgca gaatattagg tctatcacgt cagtcctatt attatcaatc
      421 aaaaccaaag aaagacgaat cagaacttga agaagtagtc gctgaagaat ttatccgcag
      481 ccgaaaggcc tacggctcaa gaaaaataaa aaaagcctta tcaaaacgag gcattcagat
      541 cagccgacga aaaattagta gaatcatgaa aaatagagga ttaaaatcga gctatactgt
      601 tgcttatttt aaagtac
//
LOCUS       DAPBBV010000143          616 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.153, whole genome shotgun sequence.
ACCESSION   DAPBBV010000143 DAPBBV010000000
VERSION     DAPBBV010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.153"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            51..>616
                     /locus_tag="RD486_002896"
     CDS             51..>616
                     /locus_tag="RD486_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HDT7664540.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTT"
BASE COUNT          223 a          103 c          120 g          170 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccac
//
LOCUS       DAPBBV010000144          581 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.154, whole genome shotgun sequence.
ACCESSION   DAPBBV010000144 DAPBBV010000000
VERSION     DAPBBV010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.154"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>581
                     /locus_tag="RD486_002897"
     CDS             <1..>581
                     /locus_tag="RD486_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7664541.1"
                     /translation="VVQGWTPDVIVGRAAFPISCSARTIYRMFKKGLFDSSDLPMKGK
                     RKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHLEGDTIVGLKHKSAVITLVERLS
                     KVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIY
                     FADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSV"
BASE COUNT          187 a           99 c          120 g          175 t
ORIGIN      
        1 gttgttcaag gatggacacc cgatgtgatt gttggtcgtg cagcgtttcc tattagttgt
       61 tctgctcgta ccatttatcg tatgttcaaa aaggggctat ttgattcttc tgacttaccg
      121 atgaaaggca agcgtaaacc gaatggacat caagaaagac gtggaaaaca aactttccgc
      181 cgctctattc atgaacgtga aaaggattat agccaattct caaatgagtt tggtcacctt
      241 gaaggtgaca ctatcgtagg tctgaaacat aaaagtgctg taattacctt agttgaacga
      301 ttatcaaaag ttatcatcac attgaaaccg tgtggtagac aagcgattga tattgaaaaa
      361 aaattaaatc aatggtttga atctgtaccg aaaaacctat tcaaatccat cacttttgat
      421 tgtggaaagg aattttcaaa ttggaaacag atcagtaatg tcaatgatat tgccatttat
      481 ttcgctgatc caggaacgcc gtctcaaaga ggcctaaacg agaattctaa cggattgtta
      541 cgtagagatg gtttattgaa atctatggat ttcaattcag t
//
LOCUS       DAPBBV010000145          528 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.155, whole genome shotgun sequence.
ACCESSION   DAPBBV010000145 DAPBBV010000000
VERSION     DAPBBV010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.155"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(5..90)
                     /locus_tag="RD486_002898"
     tRNA            complement(5..90)
                     /locus_tag="RD486_002898"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="RD486_002899"
     tRNA            complement(107..178)
                     /locus_tag="RD486_002899"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="RD486_002900"
     tRNA            complement(190..262)
                     /locus_tag="RD486_002900"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="RD486_002901"
     tRNA            complement(280..361)
                     /locus_tag="RD486_002901"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="RD486_002902"
     tRNA            complement(369..441)
                     /locus_tag="RD486_002902"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="RD486_002903"
     tRNA            complement(445..517)
                     /locus_tag="RD486_002903"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAPBBV010000146          519 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.156, whole genome shotgun sequence.
ACCESSION   DAPBBV010000146 DAPBBV010000000
VERSION     DAPBBV010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.156"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
BASE COUNT          170 a           87 c          117 g          145 t
ORIGIN      
        1 tatccataaa actaatataa agcttggtac gattctgttt gtaagacata cgaatagtat
       61 cagaggtagg agccaagctg cctgatatta aattatcgat aaagtagaaa ggttaagcat
      121 tagccgctgc aataactaat gctaggagac agcaacgtgt aaccattacc gcacgtgttt
      181 ctgaatggtg gtagcgaccg atttgaacgg ctagggcgga aatacggtgc aaatgcacgg
      241 tggtttcatg caatgcttac agggcgtatt ttgtaagggt atgtaacgga gataattccg
      301 acggtaatgg atgtgagagg ccaagccgac gctgacggta gggcaaacaa acatagttgc
      361 actctagcga tcgttattta tttttaacgg tcaaactagg gtacaactat gcttaaaaca
      421 cttcgcctca acttctggta gcaaaagtga ttttgaaagt caaaatattt tttatgagtt
      481 atttacaatt ctaaaaaaca agtgtattaa tctactaat
//
LOCUS       DAPBBV010000147          490 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.157, whole genome shotgun sequence.
ACCESSION   DAPBBV010000147 DAPBBV010000000
VERSION     DAPBBV010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.157"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..415)
                     /locus_tag="RD486_002904"
     CDS             complement(<1..415)
                     /locus_tag="RD486_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664542.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFF"
BASE COUNT          187 a           78 c           62 g          163 t
ORIGIN      
        1 aaaaaaacgg ctttccaaat gatgaaatac ctaaatctaa cttattaaga aagttgaaat
       61 ttttatattc aggaaaccat ttattaattt catgtgcagc acgtaatgca ttccctggag
      121 ttgtcaaaga gaaaattaat tctgctaagc ttattattga aaatactgat aacttataat
      181 tatatcgtcc attgacaatc aaatataaac taactatact tgttagaaca aaaaaacagg
      241 cgttgacttg ttcttgatta gttaaaaata tcaataaagg aatacttacc caatatattt
      301 ttctatttat ttcttctcct cttaagagtt gaaaaaacgg ataaaaagtt agtaaactaa
      361 atgctactgg ccactgatag ttcaaggtgg ttgctctcca accggtttcc cccattactg
      421 tcaatggtat taaacagtat atagagcaaa ccaataataa atttttaaca tttattttct
      481 caaaaacata
//
LOCUS       DAPBBV010000148          440 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.158, whole genome shotgun sequence.
ACCESSION   DAPBBV010000148 DAPBBV010000000
VERSION     DAPBBV010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.158"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            11..>440
                     /locus_tag="RD486_002905"
     CDS             11..>440
                     /locus_tag="RD486_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7664543.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          168 a           57 c           88 g          127 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag
//
LOCUS       DAPBBV010000149          437 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.159, whole genome shotgun sequence.
ACCESSION   DAPBBV010000149 DAPBBV010000000
VERSION     DAPBBV010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.159"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            33..>437
                     /locus_tag="RD486_002906"
     CDS             33..>437
                     /locus_tag="RD486_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7664544.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMS"
BASE COUNT          162 a           83 c           71 g          121 t
ORIGIN      
        1 gacaaccaat tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc
       61 aaactctagt cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga
      121 taaacacact cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca
      181 ctggttttaa ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat
      241 atggtgaatt aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt
      301 taccagccta caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa
      361 aaggtgttac gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata
      421 ctccacaaac catgtcc
//
LOCUS       DAPBBV010000150          415 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.160, whole genome shotgun sequence.
ACCESSION   DAPBBV010000150 DAPBBV010000000
VERSION     DAPBBV010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.160"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(<1..339)
                     /locus_tag="RD486_002907"
     CDS             complement(<1..339)
                     /locus_tag="RD486_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7664545.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAPBBV010000151          404 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.161, whole genome shotgun sequence.
ACCESSION   DAPBBV010000151 DAPBBV010000000
VERSION     DAPBBV010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.161"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>404
                     /locus_tag="RD486_002908"
     CDS             <1..>404
                     /locus_tag="RD486_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664546.1"
                     /translation="PEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDK
                     SDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVV
                     VTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          166 a           60 c           92 g           86 t
ORIGIN      
        1 ccagaagata aacttccagt gttgaaagca aaagatggtt atacagatgc gaaatggcca
       61 gaggaagcaa ctcaaccaat tacagcagat gatacagaat ttgtatcaag tgcaacaaaa
      121 ctggatgata aatctgacgc tgacaaatat aatcctgaag gtcaaaaagt gactacagaa
      181 ttgaataagg aaccagacgc atttgaggga attaagaaca aagaagattt accaaaagat
      241 actaagtata cttggaaaga aaaagtagat gttagcgcag ctggaaataa aaaagggact
      301 gttgtagtga catatccaga tggatcatct gatgaagttg aagtagatgt tacagtgaca
      361 gacaatcgtt ctgacgccga taaatatgag ccaacagtag aagg
//
LOCUS       DAPBBV010000152          401 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.denovo.162, whole genome shotgun sequence.
ACCESSION   DAPBBV010000152 DAPBBV010000000
VERSION     DAPBBV010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.denovo.162"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..>401
                     /locus_tag="RD486_002909"
     rRNA            <1..>401
                     /locus_tag="RD486_002909"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          125 a           87 c          117 g           72 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt c
//
LOCUS       DAPBBV010000153        13728 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.061, whole genome shotgun sequence.
ACCESSION   DAPBBV010000153 DAPBBV010000000
VERSION     DAPBBV010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.061"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(101..544)
                     /locus_tag="RD486_002910"
     CDS             complement(101..544)
                     /locus_tag="RD486_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HDT7664547.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(739..2079)
                     /locus_tag="RD486_002911"
     CDS             complement(739..2079)
                     /locus_tag="RD486_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7664548.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2361..3257
                     /locus_tag="RD486_002912"
     CDS             2361..3257
                     /locus_tag="RD486_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDT7664549.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            complement(3400..4341)
                     /locus_tag="RD486_002913"
     CDS             complement(3400..4341)
                     /locus_tag="RD486_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDT7664550.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4467..5588
                     /locus_tag="RD486_002914"
     CDS             4467..5588
                     /locus_tag="RD486_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7664551.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            5846..7348
                     /gene="eat(A)"
                     /locus_tag="RD486_002915"
     CDS             5846..7348
                     /gene="eat(A)"
                     /locus_tag="RD486_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDT7664552.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            7376..7942
                     /locus_tag="RD486_002916"
     CDS             7376..7942
                     /locus_tag="RD486_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7664553.1"
                     /translation="MVKENFVNEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQALAEKVVDLPVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELISYE"
     gene            8154..9215
                     /locus_tag="RD486_002917"
     CDS             8154..9215
                     /locus_tag="RD486_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7664554.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9218..10114
                     /gene="murQ"
                     /locus_tag="RD486_002918"
     CDS             9218..10114
                     /gene="murQ"
                     /locus_tag="RD486_002918"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDT7664555.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            10128..12110
                     /locus_tag="RD486_002919"
     CDS             10128..12110
                     /locus_tag="RD486_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7664556.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="RD486_002920"
     CDS             complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="RD486_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDT7664557.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            12837..>13728
                     /locus_tag="RD486_002921"
     CDS             12837..>13728
                     /locus_tag="RD486_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7664558.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLII"
BASE COUNT         4457 a         2489 c         2896 g         3886 t
ORIGIN      
        1 cacaacctct gattcacggt gttccagaag tagcttcttc ttatttcttg aagttgatca
       61 cttctggaac atcctctttt tttatttgga tggataatgg tcattccatt tctttgatca
      121 tttttttcat tttgtcgatt tcttcttctt gtgcctgaat gatttcttcc gctaattttt
      181 ttacttcagg atcttttaaa tcagctcgtt tacttgtcaa gatagcaata gagtgatgag
      241 ggatcatcgc cttcatccac gccgtatcgt tgacagttgt ttggcttcgt accataaata
      301 aggaaccggc aaaaacaaga agactagcgg ctaaaatcat agcatttatc tttttgtttt
      361 catacatttt ccacatgaac aacaacatga tgactgccat gactgcaccc atcatcaacg
      421 ccatgaatac acgtgtgcga ctgaagaaga tatgatcaag cgcataaaca ttcaaataca
      481 tcataccaaa catgactacc gtcgaaacac caatcatcaa caaaaacttc caatactttt
      541 tcatttaaaa caaactcctt tttcttcatt cctttcttct atcatgtcat gagcgtggag
      601 aacaatcaat taatctgcac agatggtttt tgaacaccgt ttattcggaa aaaagaactg
      661 caacaatttt tgtcgcagct cctttttttc aatagctcca gatattcaat ataaatagaa
      721 taaaattctc tattggtttc attcattcgt caagacgaaa gcatcattct ttttttgata
      781 actgaaataa atgaacaggt aaagcaaacc ggtcaataca gttaccccaa tggagttcgt
      841 gaataggata ccaaggaaaa tcaaccataa gactgctaat gcaaaaaagc tgattccttt
      901 gtcccataac gttcctttcc ttagtgtcag tacaaaggac gcagcactga taatgatcca
      961 gatcaataat actgtatagg aaagagaacc tgccagatag ccaaataatt tgtcaccgac
     1021 aaaataagaa agagccacac ctagataaag aacactggta caaaacagca cagcacgttg
     1081 cggtacttga tgcttgttta aaacagctag ttttctagag gaacctttcc gatctttcaa
     1141 gcggaagaac aaaattctcg aagaagcata tacacctgaa ttgatagacg agaacagagc
     1201 aagaacaatc acgaaattga cgatatctgc cgcaaatgga atattcattt tttcaaatac
     1261 catcacaaaa ggactaacgt tcgtgcctgc taaagtattc caaggaaaaa taatcaaaag
     1321 caaaaataaa ggaataatgt aaaaggaaat gattcttccc atgacgcctt tgattgcttt
     1381 aggaatcgca cgtttaggat catctgcttc gcttactgtg atagcaatca actcagaacc
     1441 gccgtaagaa tagataacta caagcaaaga actgatgatt cccttcatac cgtggggagt
     1501 aaaaccacca tgatcagtta attgttgaag ggtagggaaa acaccagtac ccaacatttg
     1561 ctgaccgaca agataagcag caaaaatgat caataggata atgacactga ttttagcaaa
     1621 ggccagccaa tattctgtct ctgcgaataa tcgtaccgaa taaagattga tgatagtagt
     1681 taaaacagcc aacataaaaa caaataccca agctgggatg tgggggaacc acaactgtaa
     1741 aaaggaagca gctgcaacag cttcagcaat gatattgata atccacatgg accagtagac
     1801 ccaatcggta aaatcggcag catgagcacc tagatatgga cgaatcaatc cagataatcc
     1861 gtggtgcgta tcaccaccac ttaaaacaat ttttcccaga cctttcatca cgatatataa
     1921 aattatgccg ccaatcaaaa aagcgatcaa tacagaaggg ccggcgattc caatcgcttc
     1981 gccacttcct ttaaatagac ctgcaccaat cgctccacct aaagctagca tggtgatatg
     2041 tcgggagcta agttgttttt tcaatttttt atcttccata aataacctct ttcttttaaa
     2101 ttcacaatca aaatgcatag taagaataaa tagtaagaat aaatagtaat aataataatg
     2161 actaatgata acaaattttc agataattac aactattcag aaaacttttg ggcatatttt
     2221 aatggaagaa tgatttattt catcgtattt tcatagaaat gttaaatttt tataaaaata
     2281 ataggaagcg ttttactggc tttttactat ttaaacaggc tatcatagga aaaagtgaca
     2341 gagaaagtga ggcggaacag atgaacaaaa acgacgtatt gctaattgcg aaaaataaat
     2401 cactttattt ttttccttcc atccgctctt tagatgtttg gtccggaaaa gatttactac
     2461 agtcggaatt cattaaatca gctcgacaac agttggcaaa ttatcagctg atcgtttttt
     2521 tagattatgg atttgatatg gagatggctc gacgcgtgcg tccatttacc aatgcaaaaa
     2581 tcgtgttatt tttttggaac cactttaaag cagaacacga ggcgatgctg aagcaggcac
     2641 aagatgaacc ggcaatcgat gagatttatc attttgattt tttagaagcg aaagaacttg
     2701 gactaaaaca taatagttcc ttttattcga aacatatgga tttttcttct agcgaaccaa
     2761 agacggatct attttttggt gcaacaaata acggcagaaa agaacgggca gaaaaatata
     2821 agcaggaatt tacaaaaaga ggtgttacga ccaattactt tattcttccg cttcgaggaa
     2881 atgaacaacc tggatacctt acttatgaag aatatctgaa aaaaaccggg gaatcgaggg
     2941 ggattctaga actgttgcgg gaagggcagc aaggagtgac tttgcgaacg tttgaatcta
     3001 tgtattttca aaagaaacta gtgacagata atcaagccat agctcattat cagttttatc
     3061 attctgaaaa tatttttttg cttcaagaac gtgatttaga tgaattaccg gaatttttgc
     3121 atacgccatt tcaaccaatc ccatcagaac tgttggaatt ttttgatgca gaaaattggg
     3181 caaaacgttt tttcactact gactccgcta tttatgaaca atatgaatac gatctttcct
     3241 ctgttaaaaa taaataaaag tgccaaccaa tcatagatga aaataaacaa gcgcaattct
     3301 tatggcaaca tgagaattgt gtttttcttt ttgaactttc atgggggtaa aaaaatgaga
     3361 accagctgct gatccagctg attctcatca gagagccttt tattctgcgc caaggattcc
     3421 ttcttttgca tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt
     3481 ttgtcctttt cgccaaacgg caccattgat gtagtcgatt tcagtcaaac gatggttttt
     3541 gatcaggtct tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga
     3601 agcaatatgt tggtacactt cttcttgatc taatgtgatt ccttcttttg ctgcgataga
     3661 agcaaactca gatacaatcg ttcgaaccat gccctctgcc gctttttgcg cacctaattc
     3721 agcaatatta caatccaata tcgtgcataa tccatttaat gttccgttta cacaagcttt
     3781 tcgccaaatg gaataacgaa cattatgact atagattgga ttcaattttg cttcttgaaa
     3841 gacttctaca actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat
     3901 ttctccatca cctaataatg tgacttttcc gggaccagct agaccagctg tccacatcgt
     3961 gatcccaaat aagatatttt tctttggtac atatttttcc agtacatctt catgacctaa
     4021 tccattcagt aaacacaaaa cataagtatt ctcagtaata atggattgga tcgaacgaaa
     4081 catatcatct aattgattcg cttttgtcaa ggctacgatc aaatccacgt gtttgttgct
     4141 ttcgatgatt tcttctggtg aatagattgg cagttttgca actacttctt tgccattaaa
     4201 gtcagcaatc aatccatttg tacgaatggc ttcaatgtga gcaggccagc gatcgatcaa
     4261 gacgacctca tttccgcttt gatgcaacat taatccgatt cggctgccca ttgctccggc
     4321 tccagctatt gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta
     4381 tatagaaaaa cagaagaaaa tagcattgtt ttgtttgaaa aaagtgaaaa aaagtgtctt
     4441 acttaagaag aaagtgaggg atatagatgg atattttggc ggcaatcgat tcatttaaag
     4501 gaagtgcttc ttcatttgaa ttaaatcagg cagttctaaa tggttgggaa gaccgtaaag
     4561 gaagaaaaat caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt
     4621 acgcgctcgg gggaacctgg cgtacgattg atgggatgga tctcttattt cgtcagcgaa
     4681 aaatcagtta tttattgacg aactggcaag gaaaaaatac cgcagtcatt gaatctgcac
     4741 aagtattagg attagattta cttgataaac caacggatca aaccatccga cttgcttcta
     4801 gttatgcctt gggagagctt atcaaagata cactgcttca agaagtggaa caaatcattg
     4861 tcactttagg aggaagcgga tgtagcgatg gtggtctagg attactccaa tctttgggtg
     4921 cttctttaga agggtacaca gaaggaaatc ctttgttatc tactagaaaa cttcatttgg
     4981 atcgaaggaa cgttcttgtt tctaaagtaa aagtgatcat cgctgcagac gtgaccaacc
     5041 catatacagg tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaacggata
     5101 cgacgttagc tttcttggat aaacaagctg aaaagattgc tcagcagata aaagatgttt
     5161 gggaggtgga tttagatgac atcccaggaa gcggagcagc aggcggtatt ggcggagccc
     5221 tttttttgtt aggagcgaag atggtctctg gttttgagtt ggtcagccaa atcactggat
     5281 tagaaaaaca gatcgaacaa gcggatgtca tcattacagg agaagggcgg attgatcagc
     5341 aaacaatcca cggaaaagtt ccatatggcg tagcagtgct tgcaaaaaaa tatcgaaaac
     5401 caataatcgc tatttgcgga agtagagacc gagagctgga aggactcttt gattttctcc
     5461 ccattgtctt aagcattcaa ttaggaccaa tcgatttaga ggaagcaatg gaacacaggc
     5521 aaacattaga aaaaacagaa atcttaggac agacactcag cagatttttc aacattctcc
     5581 cgaagtagtt gacaaaaaca atttctttat gctatcgtaa tttcaaatat aggacaaagt
     5641 gagggatccg tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct
     5701 tgtggagaca agggagcagt gtgcagattt tcgggattgg cttggttctt tcgatgtatg
     5761 ggtctttttg tgtgccccaa cccttgcatc ctctttagcc agttctgaaa ataggactgg
     5821 tcttttttta cgaggtgatg gaataatgtc taaaatcgaa ataaaaaatc tgacattcgg
     5881 ctatgacagc caaggcacat tattatttga acaagccaat ctaaactttg acacacaatg
     5941 gaaactagga cttatcggac gaaacggtcg aggaaagaca actttactga atatcctgca
     6001 aaacaaactc ccttatcaag ggcaagtgat ccatcagcaa gcgtttgtct atttcccgca
     6061 gcaaacaaaa gataaagagc gtttgaccta ttatgtgtta aatgagatta tggattttga
     6121 gatatgggaa attgaaagag agctccaact gatgcaaaca gatcctgaaa tcttatggag
     6181 agaattcagc acactatcag gaggagagaa gacaaaagtc ctactggcac tcttatttgt
     6241 ggatgacact catttcccgt taatcgatga accaacgaat catttggata tctctggcag
     6301 aaaacaagta gcggcttact tgaaaaagaa aaaacaagga ttcatcgtgg tgagtcatga
     6361 tcggggattt atcgatgaag tagtggacca tgttttagca atcgaaaaga gccaactgga
     6421 actttatcaa gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga
     6481 aatagctaaa aatgaaaaat tgaaaaaaga agtcagcagg ctaaagaaaa cagcagctga
     6541 aaaagcagaa tggtctcgtt cccgagaagg ggacaaaaca aagaaaaaag tcggattcat
     6601 cgatacggaa tctaggcgag tgaataaagg agcagtaggc gctgatgctg cacggacgat
     6661 gaaacgatct aaagcaatcg tgaatcggat ggaaacccag atcagtgaga aagaaaaatt
     6721 attaaaagat atcgagtata tcgatgcttt gacgatgaat agccaagtgt ctcatcataa
     6781 acggctgtta agcgtagaaa atcttcaatt agggtatgaa aatctgttat tcgagccagt
     6841 tcattttacg atcgaacctc atcagcggat ggcaatttca ggtcctaacg gcgcgggaaa
     6901 gtcatccatt atccattatc ttctggggac attcaacggc aaggttgtag gagaaaaatc
     6961 ccagcccaaa catttgacca ttagttacgt acgccaaaat tatgaagaca atcgagggac
     7021 attggcggaa ttcgcgaaga aaaaccgagt agactatcaa gcatttttga ataatctccg
     7081 aaagcttggg atggaaagag atgtttttca taataaaatc gaacagatga gtatgggaca
     7141 acggaaaaaa gtggaattgg ctaaatcttt atcccaacca gctgagctct atatatggga
     7201 tgaaccattg aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgattttgaa
     7261 cgtgaaacct gctatgttac tagtggaaca tgatcaaacc tttctagata aagtatctac
     7321 tgagattatt tctcttgaga aaatctaaac cttgtaatct caaagacaac aaggtatggt
     7381 taaggagaac tttgtcaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga
     7441 aacaacttgg aacgcacaag gattagtttg cgggcgagca gatgtgccgc tgactgaaaa
     7501 aggacagatg caggcacagg cactagcaga aaaggtagta gatttgcctg ttccaatcac
     7561 gaaaatcatc cattcccctc ttcaacgagc aagagataca gcacaagcag tagttgatcg
     7621 tctcaatttg ccgatgaccg ctgatgagcg attggtagaa atggattttg gggattatga
     7681 cggactgcca agcaaagatg aaaactttca aaaagcgcgt ttagcgtttg ctgtacgttt
     7741 cccaaatgga gagtcggtct tagatgtgta cgcacggatc gttcctttat tgaaagaatg
     7801 catggaagac gaagaaaatg tctacttgtt agtctgtcat aatgccttga taagagtgat
     7861 caatgcttat tttcatccaa tgcctaatga agggttcttt acattcatgg tagacaatac
     7921 agaattaatt tcttatgagt aattagactt ttgtgttatt taaataaaat gtttcaaggc
     7981 actgcttttg cttagcagtg ccttttttgt ggctgtgtca attcttttgg cattataaat
     8041 ccaattttta gaaataaaat ttaattattt taacaaaagt attgaaattt tgtttcttta
     8101 gatatatact ctagtcatag aaatgaagac ggatacagaa aaagagggat aatatgtttg
     8161 gcttttcaat atttatgaat gattctttgt cagaagagaa gaaacagtat atccgccaaa
     8221 tggcatccaa tggctttgtc ggtattttca cttccatgca tataccggaa gatgatgttt
     8281 cggcttatca aaatcgattg atcgaactag gaagcgaagc gaaaaagaat aaactagagt
     8341 tgatggtcga tatttcagga gaggcattga aacgagctgg cttttcatta gaagatctaa
     8401 cacccttgaa agcaattggt gtaacagggt taagaatgga ttatcatatt tctaatcagc
     8461 agatcgccga ctggtcacat caattgaaaa tcagtttgaa tgccagcacg atcacgccta
     8521 atgatatcga tgagttgaaa gaagcagcgg ctgatttctc acagattgaa gcttggcata
     8581 attattatcc acgtcttgaa acagggttgg acaaagaatg gtatcaggaa aaaaatcaat
     8641 ggctcaaaac tcaaggattc cttgtacaag gctttgtacc aggagataca gagttgagag
     8701 gtccactgta tcaaggatta ccaactttgg aagaacatcg agggatccat cctctggcag
     8761 gtgctcttga tctattagca agtaacacgg atattgttta tatcggagat gcaggtctgt
     8821 cagaacacgt tcaggagcaa tttgcttctt tccaaaaaga acagacagtc ttgctccata
     8881 cggaacctgt agatgaagtt ttttacgaat atatattagg aaaacatacg aatcggcaag
     8941 atgatgcaag agatgtcata cgaagcgcag atgcgcgttt tcgagagatt ccgccaatcc
     9001 cagtaagaaa tacagctaag cgtatgaaag gatctattac tttagataac gaaaagtatt
     9061 tgcgctatat gggtgagatc caattaacta aatatgattt gccagcggat gaaaaagtga
     9121 atgtagtagc caaagtcatc aaagaagaac taccgctgat caaccaaatc aaagctggta
     9181 tgaactatca atttataaga aaagaaggaa gataaaaatg agcaaaatca atttagagaa
     9241 cctaacaacg gaacgcagaa accaagaaac ttttggatta gatgaaatga gtatttctca
     9301 agcagtccaa ctcatgaaca aagaagatca gaaagtggcc gctgctgttg aaaaagaact
     9361 gccaagtatc gagccagtga tcgccaacac gattgaatcc tttaaaaaag gtggtcgctt
     9421 gatttatatg ggagctggaa cgagtggtag acttggtgta ttagatgctg ctgaatgtgt
     9481 accgacattc ggtgtagaac cggaaatggt cataggccta attgctggtg gagaagaagc
     9541 aatgactgta gccgtcgaag gagccgaaga ttcttatgaa ttagggcaag aagatctaat
     9601 caagctgaat ttaacaaaaa atgatatagt tattggtatc gcagctagcg gtcgtacacc
     9661 atatgtgatt ggtggattag attacgcaaa atcgattggt gctgttacag gaacgatttc
     9721 ttgcaataaa caagcagaaa tcagcgagca tgcggatttc ccaatcgaag tcgatgcagg
     9781 accagaattt ttgacaggct ctactcgatt gaagtcagga acagcacaaa aactgatttt
     9841 gaatatgatt tctactatca gtatgatcgg tatcggtaaa gtattcaata acttgatggt
     9901 cgacgtcaaa ccaacaaatg aaaaactaat tgaacgctca aaacgaatca tcatgcaagc
     9961 gacagaagct gactacgaaa cagctgaaaa gtactttgag gaagcagatc aaaatgtcaa
    10021 actggctatc gtcatgattt tgacaaatag tgataaagag gcagctcaag caaaattagc
    10081 tgaagcaaac ggttttgtaa aaggaacctt atgaggggga aaagaccatg gcaaaaaacg
    10141 aattgacttt ggaagaactg gcaaaacaaa tttatcaagg agcaggcggt atgggcaatg
    10201 ttgaaagcat tgtccactgc atgactcgtg tacgtatgaa ggtcatcaat gatgatcttg
    10261 taaatgtctc ggaattaaaa gcgattccag gagtacttgg cgtagtagag gatgaacagc
    10321 tccaagtcat catcggacct gggaaagtga acaaagtagc gcaggaaatg gttgacttag
    10381 caggcgtgaa attaggagaa aaacttcctt ctgctagtgc aactacagca agttcttctg
    10441 catctggaaa agaccgtgta aacgaacggg cacaagaaat gaaagcggca caaaaatcga
    10501 aacaaaaacc ctctaaaatc aaatcggtat taaaagacat ctctaatatc tttgtaccaa
    10561 tgatccctgc atttgtcggc actgggatcg tggcagggat tgccgcagtt ttagcaaact
    10621 tagtcacagc tggaacacta gacgcaggaa catggcaaca atatatcgat gtgatgaaca
    10681 tcttgaaaaa cgggatgttt agctatctag ttatctatac aggtatcaat gctgcacaag
    10741 tttttggtgc aacgccaacg cttggtggag ttatcggggc tgttgtgatg ctgacaggga
    10801 tgaatccaga agcaccactg aaaaacttgt ttaccggtga agctcttgca actggacaag
    10861 gcgggatctt aggtgttatc ttcgcagttt ggttattgtc aatcgttgag aaaaaactgc
    10921 ataaagtagt acctgatgcg gtagatatca tcgttacgcc aactctttcc ctgattgcca
    10981 tcggtctgat cgaaattttc ttcatcatgc ctttagcagg gttcatttct gacggcatgg
    11041 tcggtgggat caactgggta cttggtgttg gaggagcatt tgccggcttc gttctaggta
    11101 cattattctt gccaatggtc atgttcggac tacatcagat cttgacgcca atccatgtac
    11161 aaatgattga tgaaactggt cgtaccttat tgcttccaat ccttgcgatg gccggagcag
    11221 gacaagtggg tgcagcattg gcattatgga tccgctgcaa aaaagacaaa gaattaacag
    11281 aaatgatcaa aggggcttta ccagtcggaa tcttaggaat cggcgaacca ttgatttacg
    11341 gagtaacatt acctctagga cgtccattta ttactgcttg tatcggtgga ggtatcggtg
    11401 gggcagtgat cggaatgatc ggaaatgtcg gagcaatcgc tattggacct tcaggagccg
    11461 ctttgattcc attgatctct gatggtaaat ggttaggcta tatccttggt ttattggctg
    11521 cttacgctgg tggcttcgtt gctacattct tcttcggtat tcctaaagac cgtttagaaa
    11581 aagaagaact agcgaccgaa acagccacag taaatgaagt acctgaaaaa gcagtacctc
    11641 aagcttcagc tgaaagtgtg actatcttat catcagttgc tgacggaaca gttgtttctt
    11701 tagataaagc aagtgaccca gtttttgcac aaaaaatgat gggtgaaggt tactttgtag
    11761 aaccagaaaa cggacatatc tattccccgg ttactggagt aataagttct gttttcccaa
    11821 caaaacatgc tatcggcatt acgacaccaa atggcttaga aatcttgctt cacatgggca
    11881 tcaacacagt tgacttaggc ggtacgccat tcgatgtgaa agtaacagaa ggacagcaag
    11941 tgacacctga tacgcttgta gcagaagctg acttagaagc aatcaaagca gcagacaaag
    12001 aaacctccat gatcgtcttg gtaaccaata tggatcgtgt aaaaaacttt gtcttggaaa
    12061 aaacaggtaa agcgaaagca aaagcacctg tgatggatgt caaagcttaa taagaataga
    12121 aacaatagag aacataaaaa gaagaagccg aaatttattt ttcagcttct tcttttgtgt
    12181 tatttatttt tttctgccaa aatttgataa acgcgtgtca catcagatgg tgttccccgt
    12241 aattcataat ctgccaagaa aggaaagccg aatctttgtg cgtattgttt ggctgtcaga
    12301 caatattgat tgttgaagtt tttattaccg ctaccgacta caccaaggca aagtttatga
    12361 ttgtcttcgt attccagata ttcgcgcatc gtttcggtca agatttctgt gtcaccgttg
    12421 tctaacccat tcccgccgtc taaataagta ggaacgaaag taaaaaatgg ttctgtttct
    12481 ttcgtaaaat cactattttc atggatttct tttaaagtaa cttcaggatt gacaggatct
    12541 tctgcatgca ttttttcagc atattctgct agatgtttgg caaaagcacg cgtatttcct
    12601 gaaatcgata tatataaaat gttcatggat catcccccaa ttctttccct ttagtatagc
    12661 atctttttaa gtttttttgg tggtgtaatt tggaaaggga ctaggcgctt tgcttgtata
    12721 atgagaaaaa agtcggtaga attatatttc tattaaagtt tttattaatt aagtaaaaat
    12781 aaaaaaggtt tgttatactt tttgataaaa gcggttttac tttggaggat gcttacatgg
    12841 atacagagca acagaaaaaa ggaattggtt tgattccact tgctgcctta gtgattggtt
    12901 cagcgattgg aggtggcgta tttggtatta tgacggacat ctccggatcg gctggtggcc
    12961 cagctatctt cagctgggta ctcgtaggaa cagcaatgtt gatgctctcc ttatcgatca
    13021 ataatatcaa taaaaaacgt ccagatttaa aaggcgggat ctttagttac gcagaagaag
    13081 gttttggccg tttcgctggt tttatcagcg gttggggtta ctggctcaca tgctggttag
    13141 gaaacgtggc gttcgcaaca ttgttgatga gtgcattagg ttatttcttc cccgtattcg
    13201 aaggtggtca aaatgtggca tcgatcgtga tgagtacgat cttcttatgg ggatatgcat
    13261 ggctagtgaa tcgtggagtt gaaaatgcta gctttgtcaa tgctatcgtc acattttgta
    13321 aattagtgcc attattttta tttattgtag tagctatcag caccttttcg atccaacaat
    13381 tcattaataa cttttctagc gatatcatat tgaatgcgaa tgggcagccg atcccgtttt
    13441 ctagtcaagt attgagttgc atcatggtga tgctctgggt attcgttggt attgaaggag
    13501 cttctgtcgt aggttcacga gcaaaaaaac aatcggatgt tgggaaagca acgattctag
    13561 gaatattcgg tttgatcatt atttacgtct tggtttccat gcttccatat ggcacaatga
    13621 cgatgaatca gctgcaaacg atcaaagcgc aacctgctat gggatatgta tttgaaatga
    13681 tggttggtaa atggggggcg gtcgtgatca acggcggttt gatcattt
//
LOCUS       DAPBBV010000154        13213 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.063, whole genome shotgun sequence.
ACCESSION   DAPBBV010000154 DAPBBV010000000
VERSION     DAPBBV010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.063"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(204..2162)
                     /locus_tag="RD486_002922"
     CDS             complement(204..2162)
                     /locus_tag="RD486_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7664559.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="RD486_002923"
     CDS             complement(2159..3031)
                     /locus_tag="RD486_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7664560.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="RD486_002924"
     CDS             complement(3373..4245)
                     /locus_tag="RD486_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7664561.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="RD486_002925"
     CDS             4373..4942
                     /locus_tag="RD486_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDT7664562.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="RD486_002926"
     CDS             5009..5746
                     /locus_tag="RD486_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7664563.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="RD486_002927"
     CDS             5977..7245
                     /locus_tag="RD486_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7664564.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="RD486_002928"
     CDS             7732..8196
                     /locus_tag="RD486_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7664565.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="RD486_002929"
     CDS             8180..8809
                     /locus_tag="RD486_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7664566.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="RD486_002930"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="RD486_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDT7664567.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="RD486_002931"
     CDS             10688..11134
                     /locus_tag="RD486_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDT7664568.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="RD486_002932"
     CDS             complement(11333..11848)
                     /locus_tag="RD486_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7664569.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="RD486_002933"
     CDS             11965..13167
                     /locus_tag="RD486_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7664570.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DAPBBV010000155         7959 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.078, whole genome shotgun sequence.
ACCESSION   DAPBBV010000155 DAPBBV010000000
VERSION     DAPBBV010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.078"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            128..1564
                     /locus_tag="RD486_002934"
     CDS             128..1564
                     /locus_tag="RD486_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7664571.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="RD486_002935"
     CDS             1753..4200
                     /locus_tag="RD486_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7664572.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="RD486_002936"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="RD486_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDT7664573.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="RD486_002937"
     CDS             complement(5690..6793)
                     /locus_tag="RD486_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7664574.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="RD486_002938"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="RD486_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDT7664575.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2665 a         1359 c         1729 g         2206 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DAPBBV010000156         6706 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.084, whole genome shotgun sequence.
ACCESSION   DAPBBV010000156 DAPBBV010000000
VERSION     DAPBBV010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.084"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            111..194
                     /locus_tag="RD486_002939"
     CDS             111..194
                     /locus_tag="RD486_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HDT7664576.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="RD486_002940"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="RD486_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HDT7664577.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1226..1486
                     /locus_tag="RD486_002941"
                     /pseudo
     CDS             1226..1486
                     /locus_tag="RD486_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1649..2314
                     /locus_tag="RD486_002942"
                     /pseudo
     CDS             1649..2314
                     /locus_tag="RD486_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2350..2595
                     /locus_tag="RD486_002943"
     CDS             2350..2595
                     /locus_tag="RD486_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7664578.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2698..3567
                     /locus_tag="RD486_002944"
     CDS             2698..3567
                     /locus_tag="RD486_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDT7664579.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3548..4282
                     /locus_tag="RD486_002945"
     CDS             3548..4282
                     /locus_tag="RD486_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7664580.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4315..5223
                     /locus_tag="RD486_002946"
     CDS             4315..5223
                     /locus_tag="RD486_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HDT7664581.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5220..5762
                     /gene="sat4"
                     /locus_tag="RD486_002947"
     CDS             5220..5762
                     /gene="sat4"
                     /locus_tag="RD486_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HDT7664582.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5855..6649
                     /locus_tag="RD486_002948"
                     /note="aph(3')-IIIa"
     CDS             5855..6649
                     /locus_tag="RD486_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HDT7664583.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT         2349 a         1009 c         1401 g         1947 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 aacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 attcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac tactgacagc
     1141 ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat aaggggtaca
     1201 aattcccact aagcgctcgg gaccccttgt aggaaaatgt cctaagtgtg gcaacaatat
     1261 tgtattaaaa aaatcgtttt atggttgttc aaattatcct gaatgtaagt ttactttagc
     1321 tgaacatttt agaaagaaaa aactaaccaa aacgaatgta aaagaattac tggagggaaa
     1381 agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag ccctacaatg ccgttgtaaa
     1441 aattggggaa aagggatata ttgattttat ctctttttca aaataaacat ggggctgacc
     1501 caaaagtagc tcctatatga aaaatagagg tctttccatt tagatagtag tggaaagacc
     1561 tctatttatc ttttgaaagt gaatacaaaa ataaagcaca ctctgctata atataggtga
     1621 ttaatccatt tgagagaggt gctttatcat gtatcaaaat tataccataa accaactttg
     1681 tttgcctata gatcttgaaa ttaaattaga agaaaatgat tttgctcatg ccattgtgca
     1741 gtttgttgac tctattcccg atgaagtctt tcttccttat tatcaatcta tgggtagacc
     1801 ccaatatcat cctcgtatgc tactttccat tattctttgt gcctatattc aaggggttta
     1861 ttcgggccgc caaatacaaa atatgctgat agatagtatt cggatgcgct acttatctca
     1921 agagcaattc cctaactttc gtactattaa tcgttttcgc gttcatccga ttatgaacga
     1981 tattctagat cattcatttg ttcaatttcg tgagctactg gttcaaagtg gcttaatcag
     2041 tggcagtgct ctatacattg atggtacaaa aattgaagcg gatgcgaata aatactcttt
     2101 cgtttggaaa aaaagtattt taaagtataa ggatagcctt gatcaaaaag cccttgaaaa
     2161 ctaccaacaa atggtggaaa caaaaatctt acctgagtta atagatgatt taaaggatga
     2221 actttctata gaagagattg aaaggattcg tcaatctttg gaagaaaagg aaaatcaatt
     2281 aattgaagcg attgaccaaa ccgaaacagt agaagggggc tgacccatta ttaataagga
     2341 gtggacaaca tgattgatgt aaatgagcta ttggaagaag ctattagaga aactgaaaat
     2401 ctaaatgatg gcgaagtttt tcttgttaaa gatttattca agggatatgt ggggaatagg
     2461 atacccagaa aggatcgact tctgcttgga acgttatttt taaaccatgt tagcaaaatg
     2521 aatggtaatt taaaggctat tgaaaagact tcatctaatc agcagaggta taaaaagaca
     2581 attgataagt tttaactatc ttttgtgaaa ttaaaaaaat tataaatatg ttgagtagaa
     2641 gcaaaagatt tggcttggaa tttttacagc agtgaatcga taaaaggagc atgcttgatg
     2701 gtagataata ttattaaatc agtagcagag aaattatcct ctctgtctta tatagaaggt
     2761 attgttttag gtggttcacg tgcaaggggc acccatacag aggattcgga tatagatatc
     2821 ggcatctatt acaattcaga atcatttgac ataaatacta ttaatcaatt cgctacaaag
     2881 ctggatgatg agcatagaaa taaccttgtt gtacctcccg gagcatgggg tgattggatt
     2941 aatggcggcg gatggttagt cataaacggg tatcatgtgg atttaatttt acgtgatatt
     3001 aaacgtgtgg aacaaataat gaaagataca gagcacggaa ttgttactgc caattatcag
     3061 actgggcatc cccatggtta tattagtgca atgtatcgag gagaattagc gattagcaaa
     3121 atactatatg ctaagaatga aagcttatgc gaattaaaaa aacaggcaga aacttatccc
     3181 aatgctttgc agaaaagttt agttaacttt tttatgtttg aagcagggtt ctctttaatg
     3241 tttgtaaaag caaattcggg aacagacgat aaatattata ttgcgggtca tgtttttcgt
     3301 atagtttcat gtttaaatca agtgttattt gcatgtaata atgcttattg tatcaacgaa
     3361 aagaaagcta taaaactgct tgaaactttt gaacataaac ctgaaaaata taccgagaag
     3421 gtaaatcata tttttgaagt actcggtatc tcactttttg aatgctacga catgaccgag
     3481 aagctttata atgaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag
     3541 agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat
     3601 gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct
     3661 acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat
     3721 atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct
     3781 cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga
     3841 agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta
     3901 tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa
     3961 tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta
     4021 taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg
     4081 gacagctatg tttttggaag aaaaggttac aaaatatcat agaacactga ccacatatct
     4141 aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac agccgccaga
     4201 gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga tgctgattgt
     4261 atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat gtaaatgaga
     4321 tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga acgtattcga
     4381 attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga atttcaggat
     4441 tatgatatta catattttgt aagtgatata gaaccgttta tatctaatga tgactggctt
     4501 aatcaatttg ggaatataat aatgatgcaa aagccggagg atatggaatt attcccacct
     4561 gaagaaaagg gattttccta tcttatgcta tttgatgatt acaataaaat tgatcttacc
     4621 ttattgccct tggaagagtt agataattac ctaaagggcg ataaattaat aaaggttcta
     4681 attgataaag attgtagaat taaaagggac atagttccga ctgatataga ttatcatgta
     4741 agaaagccaa gcgcaaggga gtatgatgat tgctgcaatg aattttggaa tgtaacacct
     4801 tatgttatta aaggattgtg ccgtaaggaa attttatttg ctattgatca ttttaatcag
     4861 attgttcgcc atgagctgct gagaatgata tcatggaagg tcggcatcga aacaggcttt
     4921 aaattaagtg taggcaagaa ctataagttt attgaaaggt atatatccga ggatttgtgg
     4981 gagaaacttt tgtccaccta ccggatggat tcctatgaaa acatatggga agcattattt
     5041 ctatgccatc aattgttcag ggcggtatcc ggtgaggtgg cggaaaggct tcattatgcc
     5101 tatccggagt atgataggaa tataacaaaa tataccaggg acatgtataa aaaatacact
     5161 ggtaaaaccg gctgcctgga tagcacatat gccgctgata tagaagagag gcgggaacag
     5221 tgattacaga aatgaaagca gggcacctga aagatatcga taaacccagc gaaccatttg
     5281 aggtgatagg taagattata ccgaggtatg aaaacgagaa ttggaccttt acagaattac
     5341 tctatgaagc gccatattta aaaagctacc aagacgaaga ggatgaagag gatgaggagg
     5401 cagattgcct tgaatatatt gacaatactg ataagataat atatctttac taccaagacg
     5461 ataaatgcgt cggaaaagtt aaactgcgaa aaaattggaa ccggtacgct tatatagaag
     5521 atatcgccgt atgtaaggat ttcagggggc aaggcatagg cagcgcgctt atcaatatat
     5581 ctatagaatg ggcaaagcat aaaaacttgc atggactaat gcttgaaacc caggacaata
     5641 accttatagc ttgtaaattc tatcataatt gtggtttcaa aatcggctcc gtcgatacta
     5701 tgttatacgc caactttgaa aacaactttg aaaaagctgt tttctggtat ttaaggtttt
     5761 agaatgcaag gaacagtgaa ttggagttcg tcttgttata attagcttct tggggtatct
     5821 ttaaatactg tagaaaagag gaaggaaata ataaatggct aaaatgagaa tatcaccgga
     5881 attgaaaaaa ctgatcgaaa aataccgctg cgtaaaagat acggaaggaa tgtctcctgc
     5941 taaggtatat aagctggtgg gagaaaatga aaacctatat ttaaaaatga cggacagccg
     6001 gtataaaggg accacctatg atgtggaacg ggaaaaggac atgatgctat ggctggaagg
     6061 aaagctgcct gttccaaagg tcctgcactt tgaacggcat gatggctgga gcaatctgct
     6121 catgagtgag gccgatggcg tcctttgctc ggaagagtat gaagatgaac aaagccctga
     6181 aaagattatc gagctgtatg cggagtgcat caggctcttt cactccatcg acatatcgga
     6241 ttgtccctat acgaatagct tagacagccg cttagccgaa ttggattact tactgaataa
     6301 cgatctggcc gatgtggatt gcgaaaactg ggaagaagac actccattta aagatccgcg
     6361 cgagctgtat gattttttaa agacggaaaa gcccgaagag gaacttgtct tttcccacgg
     6421 cgacctggga gacagcaaca tctttgtgaa agatggcaaa gtaagtggct ttattgatct
     6481 tgggagaagc ggcagggcgg acaagtggta tgacattgcc ttctgcgtcc ggtcgatcag
     6541 ggaggatatc ggggaagaac agtatgtcga gctatttttt gacttactgg ggatcaagcc
     6601 tgattgggag aaaataaaat attatatttt actggatgaa ttgttttagt acctagattt
     6661 agatgtcggt tctgttgcaa agttttaaat ctactatcaa ataagg
//
LOCUS       DAPBBV010000157         5422 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.092, whole genome shotgun sequence.
ACCESSION   DAPBBV010000157 DAPBBV010000000
VERSION     DAPBBV010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.092"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(39..2657)
                     /locus_tag="RD486_002949"
                     /pseudo
     CDS             complement(39..2657)
                     /locus_tag="RD486_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2803..3378
                     /locus_tag="RD486_002950"
     CDS             2803..3378
                     /locus_tag="RD486_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7664584.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3592..4287
                     /gene="vanR"
                     /locus_tag="RD486_002951"
     CDS             3592..4287
                     /gene="vanR"
                     /locus_tag="RD486_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDT7664585.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4265..5416
                     /locus_tag="RD486_002952"
     CDS             4265..5416
                     /locus_tag="RD486_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7664586.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPGFCCKVLNKE"
BASE COUNT         1693 a         1022 c         1031 g         1676 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaacctt catccgatat ataattcaaa
       61 ataaagatcg ttttttctat tcggcccatc tcacgtaagg ctgtagctaa gctgttttgt
      121 cttgaatagg aacctagctt ccccataata agggatgctg aaactgttcc ctcccttata
      181 gaatgagcta atcgcaaaac atcctcataa ttttctttaa tgacctttgt atttatttgt
      241 ccacgtaaaa tggcttctag ttttggatac tcacttgctt tatctatcgt aaataatttt
      301 gagtccgata aatcccttat tcttggggca aatttaaatc ctaataaatg agtcagtccg
      361 aatatttggt cagtgtaacc ggcagtgtct gtataatgtt cctctatgtt tagatccgtc
      421 tcatgatgta acaaaccatc caaaacatga atcgcatctc ttgaattagt atgaataatc
      481 tttgtgtagt aagaagagaa ttgatcactt gtaaatcggt agatggtggc tccttttcca
      541 gttccataat gtggatttgc atctgcatgt agtgatgaaa cacctagctg cattctcata
      601 ccatctgacg aagatgttgt accgtcgccc caatagaaag gcaattgtaa tttatgatga
      661 aagtttacta atatggcttg ggctttattc atggcatctt catacatgcg ccattgagat
      721 acattggcta gttgcttata tgtaagtccg ggtgtggctt cggccatctt gctcaagcca
      781 atattcattc ccattcctaa aagggcagcc atgataatga ttgtttcttc cttatctggt
      841 tttcgattat tggaagcatg agtgaattgc tcatgaaatc ctgttatatg ggccacatcc
      901 atgagtaaat cagttaattt tattcttggt agcatctgat aaaggcttgc actaaatttt
      961 tttgcttctt ctggaacatc tttttctaag cgtgcaagtg atagctttcc tttttcaaga
     1021 gaaaccccat ctaacttatt ggaattggca gctaaccact ttaacctttc attaaagctg
     1081 ctggttctct ccgttatata atcttcgaat gataaactaa ctgataatct cgtattcccc
     1141 ttcgattgat tccatgtatc ttccgaaaac aaatattcct caaaatccct atattgtctg
     1201 ctgccaacaa tggaaacatc tcctgcccga acatgctccc gaagttctgt taaaacagcc
     1261 atttcatagt aatgacgatt aattgttgta ccatcatcct cgtataaatg tcttttccat
     1321 cgttttgaaa taaaatccac aggtgagtca tcaggcactt ttcgctttcc agattcgttc
     1381 attcctcgga taatctcaac agcttgtaaa agtggctcat ttgcctttgt agaatgaaat
     1441 tccaatactc ttaatagcgt tggcgtatat tttcttagtg aataaaaccg tttttgcagt
     1501 aagtctaaat aatcatagtc ggcaggacgt gcaagttcct gagcctcttc tactgaagag
     1561 acaaaggtat tccattcaat aaccgattct aaaaccttaa aaacgtctaa tttttcctct
     1621 cttgctttaa ttaatgcttg tccgatgttc gtaaagtgta taactttctc atttagcttt
     1681 ttaccgtttt gtttctggat ttcctcttga gccttacgac cttttgataa caaactaagt
     1741 atttgcctat catgaatttc aaacgcttta tccgttagct cctgagtaag ttgtaataaa
     1801 tagatggtta atatcgaata acgtttattt tcttgaaagt cacggaatgc atacggctcg
     1861 tatcttgagc ctaagcgaga cagctgcaac aggcggttac ggtgcaaatg actaatttgc
     1921 actgtttcta aatccattcc tcgtatgtat tcgagtcgtt ctattatttt tagaaaagtt
     1981 tcgggtgaag gatgacccgg tggctctttt aaccaaccca atatcgtttt attggattcg
     2041 gatggatgct gcgaggtaat aatcccttca agcttttctt tttgctcatt tgttagagat
     2101 ttactaaccg tattaaatag cttcttttca gccattgccc ttgcttccca caccattctt
     2161 tcaagtgtag tgatagcagg cagtataatt ttgttttttc ttagaaaatc tatgcattca
     2221 tgcagtagat gaatggcatc accattttcc aaagctaatt gatgaaggta cttaaatgtc
     2281 attcgatatt cactcagggt aaaagttaca aagtcgtatt cacttcgaat ttctttcaaa
     2341 tgatcccaaa gtgtattttc cctttgagga taatgatcaa gcgaggatgg actaacacca
     2401 atctgtttcg atatatattg tatgaccgaa tctgggatgc ttttgatatg agtgtatggc
     2461 caaccgggat accgaagaac agctaattga acagcaaatc ctaaacggtt ttcttccctc
     2521 cttcgcttat taactatttc taaatcccgt ttggaaaaag tgaagtaggt ccccagtatc
     2581 cattcatctt cagggatttg cataaaagcc tgtctctgtt ccggtgtaag caattctcta
     2641 cctctcgcaa ttttcattca gtatcattcc atttctgtat tttcaattta ttagttcaat
     2701 tatatatcaa tagagtgtac tctattgata caaatgtagt agactgataa aatcatagtt
     2761 aagagcgtct cataagactt gtctcaaaaa tgaggtgata ttttgcggaa aatcggttat
     2821 attcgtgtca gttcgactaa ccagaatcct tcaagacaat ttcagcagtt gaacgagatc
     2881 ggaatggata ttatatatga agagaaagtt tcaggagcaa caaaggatcg cgagcaactt
     2941 caaaaagtgt tagacgattt acaggaagat gacatcattt atgttacaga cttaactcga
     3001 atcactcgta gtacacaaga tctatttgaa ttaatcgata acatacgaga taaaaaggca
     3061 agtttaaaat cactaaaaga tacatggctt gatttatcag aagataatcc atacagccaa
     3121 ttcttaatta ctgtaatggc tggtgttaac caattagagc gagatcttat tcggatgaga
     3181 caacgtgaag ggattgaatt ggctaagaaa gaaggaaagt ttaaaggtcg attaaagaag
     3241 tatcataaaa atcacgcagg aatgaattat gcggtaaagc tatataaaga aggaaatatg
     3301 actgtaaatc aaatttgtga aattactaat gtatctaggg cttcattata caggaaatta
     3361 tcagaagtga ataattagcc attctgtatt ccgctaatgg gcaatatttt taaagaagaa
     3421 aaggaaacta taaaatatta acagcctcct agcgatgccg aaaagccctt tgataaaaaa
     3481 agaatcatca tcttaagaaa ttcttagtca tttattatgt aaatgcttat aaattcggcc
     3541 ctataatctg ataaattatt aagggcaaac ttatgtgaaa gggtgataac tatgagcgat
     3601 aaaatactta ttgtggatga tgaacatgaa attgccgatt tggttgaatt atacttaaaa
     3661 aacgagaatt atacggtttt caaatactat accgccaaag aagcattgga atgtatagac
     3721 aagtctgaga ttgaccttgc catattggac atcatgcttc ccggcacaag cggccttact
     3781 atctgtcaaa aaataaggga caagcacacc tatccgatta tcatgctgac cgggaaagat
     3841 acagaggtag ataaaattac agggttaaca atcggcgcgg atgattatat aacgaagccc
     3901 tttcgcccac tggagttaat tgctcgggta aaggcccagt tgcgccgata caaaaaattc
     3961 agtggagtaa aggagcagaa cgaaaatgtt atcgtccact ccggccttgt cattaatgtt
     4021 aacacccatg agtgttatct gaacgagaag cagttatccc ttactcccac cgagttttca
     4081 atactgcgaa tcctctgtga aaacaagggg aatgtggtta gctccgagct gctatttcat
     4141 gagatatggg gcgacgaata tttcagcaag agcaacaaca ccatcaccgt gcatatccgg
     4201 catttgcgcg aaaaaatgaa cgacaccatt gataatccga aatatataaa aacggtatgg
     4261 ggggttggtt ataaaattga aaaataaaaa aaacgactat tccaaactag aacgaaaact
     4321 ttacatgtat atcgttgcaa ttgttgtggt agcaattgta ttcgtgttgt atattcgttc
     4381 aatgatccga gggaaacttg gggattggat cttaagtatt ttggaaaaca aatatgactt
     4441 aaatcacctg gacgcgatga aattatatca atattccata cggaacaata tagatatctt
     4501 tatttatgtg gcgattgtca ttagtattct tattctatgt cgcgtcatgc tttcaaaatt
     4561 cgcaaaatac tttgacgaga taaataccgg cattgatgta cttattcaga acgaagataa
     4621 acaaattgag ctttctgcgg aaatggatgt tatggaacaa aagctcaaca cattaaaacg
     4681 gactctggaa aagcgagagc aggatgcaaa gctggccgaa caaagaaaaa atgacgttgt
     4741 tatgtacttg gcgcacgata ttaaaacgcc ccttacatcc attatcggtt atttgagcct
     4801 gcttgacgag gctccagaca tgccggtaga tcaaaaggca aagtatgtgc atatcacgtt
     4861 ggacaaagcg tatcgactcg aacagctaat cgacgagttt tttgagatta cacggtataa
     4921 cctacaaacg ataacgctaa caaaaacgca catagaccta tactatatgc tggtgcagat
     4981 gaccgatgaa ttttatcctc agctttccgc acatggaaaa caggcggtta ttcacgcccc
     5041 cgaggatctg accgtgtccg gcgaccctga taaactcgcg agagtcttta acaacatttt
     5101 gaaaaacgcc gctgcataca gtgaggataa cagcatcatt gacattaccg cgggcctctc
     5161 cggggatgtg gtgtcaatcg aattcaagaa cactggaagc atcccaaaag ataagctagc
     5221 tgccatattt gaaaagttct ataggctgga caatgctcgt tcttccgata cgggtggcgc
     5281 gggacttgga ttggcgattg caaaagaaat tattgttcag catggagggc agatttacgc
     5341 ggaaagcaat gataactata cgacgtttag ggtagagctt ccagggttct gttgcaaagt
     5401 tttaaataaa gaataaaatc cc
//
LOCUS       DAPBBV010000158         2975 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.108, whole genome shotgun sequence.
ACCESSION   DAPBBV010000158 DAPBBV010000000
VERSION     DAPBBV010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.108"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            296..1264
                     /locus_tag="RD486_002953"
     CDS             296..1264
                     /locus_tag="RD486_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HDT7664587.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1257..2288
                     /gene="vanA"
                     /locus_tag="RD486_002954"
     CDS             1257..2288
                     /gene="vanA"
                     /locus_tag="RD486_002954"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HDT7664588.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2294..2902
                     /locus_tag="RD486_002955"
     CDS             2294..2902
                     /locus_tag="RD486_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7664589.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          885 a          568 c          719 g          803 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccgc ttccagcgat gccagacttg
       61 gttgataaaa ggaggtccta agagatgtat ataatttttt aggaaaatct caaggttatc
      121 tttacttttt cttaggaaat taacaattta atattaagaa acggctcgtt cttacacggt
      181 agacttaata ccgtaagaac gagccgtttt cgttcttcag agaaagattt gacaagatta
      241 ccattggcat ccccgtttta tttggtgcct ttcacagaaa gggttggtct taattatgaa
      301 taacatcggc attactgttt atggatgtga gcaggatgag gcagatgcat tccatgctct
      361 ttcgcctcgc tttggcgtta tggcaacgat aattaacgcc aacgtgtcgg aatccaacgc
      421 caaatccgcg cctttcaatc aatgtatcag tgtgggacat aaatcagaga tttccgcctc
      481 tattcttctt gcgctgaaga gagccggtgt gaaatatatt tctacccgaa gcatcggctg
      541 caatcatata gatacaactg ctgctaagag aatgggcatc actgtcgaca atgtggcgta
      601 ctcgccggat agcgttgccg attatactat gatgctaatt cttatggcag tacgcaacgt
      661 aaaatcgatt gtgcgctctg tggaaaaaca tgatttcagg ttggacagcg accgtggcaa
      721 ggtactcagc gacatgacag ttggtgtggt gggaacgggc cagataggca aagcggttat
      781 tgagcggctg cgaggatttg gatgtaaagt gttggcttat agtcgcagcc gaagtataga
      841 ggtaaactat gtaccgtttg atgagttgct gcaaaatagc gatatcgtta cgcttcatgt
      901 gccgctcaat acggatacgc actatattat cagccacgaa caaatacaga gaatgaagca
      961 aggagcattt cttatcaata ctgggcgcgg tccacttgta gatacctatg agttggttaa
     1021 agcattagaa aacgggaaac tgggcggtgc cgcattggat gtattggaag gagaggaaga
     1081 gtttttctac tctgattgca cccaaaaacc aattgataat caatttttac ttaaacttca
     1141 aagaatgcct aacgtgataa tcacaccgca tacggcctat tataccgagc aagcgttgcg
     1201 tgataccgtt gaaaaaacca ttaaaaactg tttggatttt gaaaggagac aggagcatga
     1261 atagaataaa agttgcaata ctgtttgggg gttgctcaga ggagcatgac gtatcggtaa
     1321 aatctgcaat agagatagcc gctaacatta ataaagaaaa atacgagccg ttatacattg
     1381 gaattacgaa atctggtgta tggaaaatgt gcgaaaaacc ttgcgcggaa tgggaaaacg
     1441 acaattgcta ttcagctgta ctctcgccgg ataaaaaaat gcacggatta cttgttaaaa
     1501 agaaccatga atatgaaatc aaccatgttg atgtagcatt ttcagctttg catggcaagt
     1561 caggtgaaga tggatccata caaggtctgt ttgaattgtc cggtatccct tttgtaggct
     1621 gcgatattca aagctcagca atttgtatgg acaaatcgtt gacatacatc gttgcgaaaa
     1681 atgctgggat agctactccc gccttttggg ttattaataa agatgatagg ccggtggcag
     1741 ctacgtttac ctatcctgtt tttgttaagc cggcgcgttc aggctcatcc ttcggtgtga
     1801 aaaaagtcaa tagcgcggac gaattggact acgcaattga atcggcaaga caatatgaca
     1861 gcaaaatctt aattgagcag gctgtttcgg gctgtgaggt cggttgtgcg gtattgggaa
     1921 acagtgccgc gttagttgtt ggcgaggtgg accaaatcag gctgcagtac ggaatctttc
     1981 gtattcatca ggaagtcgag ccggaaaaag gctctgaaaa cgcagttata accgttcccg
     2041 cagacctttc agcagaggag cgaggacgga tacaggaaac ggcaaaaaaa atatataaag
     2101 cgctcggctg tagaggtcta gcccgtgtgg atatgttttt acaagataac ggccgcattg
     2161 tactgaacga agtcaatact ctgcccggtt tcacgtcata cagtcgttat ccccgtatga
     2221 tggccgctgc aggtattgca cttcccgaac tgattgaccg cttgatcgta ttagcgttaa
     2281 aggggtgata agcatggaaa taggatttac ttttttagat gaaatagtac acggtgttcg
     2341 ttgggacgct aaatatgcca cttgggataa tttcaccgga aaaccggttg acggttatga
     2401 agtaaatcgc attgtaggga catacgagtt ggctgaatcg cttttgaagg caaaagaact
     2461 ggctgctacc caagggtacg gattgcttct atgggacggt taccgtccta agcgtgctgt
     2521 aaactgtttt atgcaatggg ctgcacagcc ggaaaataac ctgacaaagg aaagttatta
     2581 tcccaatatt gaccgaactg agatgatttc aaaaggatac gtggcttcaa aatcaagcca
     2641 tagccgcggc agtgccattg atcttacgct ttatcgatta gacacgggtg agcttgtacc
     2701 aatggggagc cgatttgatt ttatggatga acgctctcat catgcggcaa atggaatatc
     2761 atgcaatgaa gcgcaaaatc gcagacgttt gcgctccatc atggaaaaca gtgggtttga
     2821 agcatatagc ctcgaatggt ggcactatgt attaagagac gaaccatacc ccaatagcta
     2881 ttttgatttc cccgttaaat aaacttttaa ccgttgcacg gacaaactat ataagcggtt
     2941 ctgttgcaaa gttttaaata aagaataaaa tccct
//
LOCUS       DAPBBV010000159         2565 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.111, whole genome shotgun sequence.
ACCESSION   DAPBBV010000159 DAPBBV010000000
VERSION     DAPBBV010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2565
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.111"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            complement(39..341)
                     /locus_tag="RD486_002956"
                     /pseudo
     CDS             complement(39..341)
                     /locus_tag="RD486_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1055..1345)
                     /locus_tag="RD486_002957"
     CDS             complement(1055..1345)
                     /locus_tag="RD486_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7664590.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1553..2244)
                     /locus_tag="RD486_002958"
                     /pseudo
     CDS             complement(1553..2244)
                     /locus_tag="RD486_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          759 a          472 c          356 g          978 t
ORIGIN      
        1 atggattttt tcatttacac aaaatatttt atactctcaa catacttgca aagtaatact
       61 acaattccta acataatcgt agaatttaat aatttccata gcataaagtg tttagaaaag
      121 aacattaaga atagttctat aataattctt gaactccatg tcttataatg ttctatcgaa
      181 gcacccaaat agccaagttc atctaatcta cttgcataaa ctacgtcatc cgctctcata
      241 gtcggcatat acatattaaa gagtaaaaag ataccccaaa tccctattag taacaagatc
      301 agttctttgt tattcgttat ttttctatta tgtttgttca tttttatact ccttcttata
      361 tttcctaata gagtataaca tagctttaag cattacttaa agataactta aaagttatct
      421 tttaaatact taattgttaa ataccttatt tgatgcaaaa gaaatctacg atagtcaaca
      481 aaaaaatttt cattatatcc agaaaaattt ttcttagtta aggacctatg gattgcagta
      541 atgcagaatt cgtcgaataa actgccaaag acatacaatc atattgcttt taaaattgac
      601 gaacaagata tagattcgtt tgtctcaaaa atccaaatgt taggtttaac tgtcgaacca
      661 ggacgttctc gtgtgaaagg cgaggcttct tcaatttact tttacgacta tgataatcac
      721 ctcttcgagt tacataccgg tactctccag gaacgtttaa aatcctacaa ttccactacc
      781 tgagactagt aatgactagt ctctttttat ggcctctgat ccccccattg agcgaatact
      841 aatagggctt cgaattgatc tgttcaatct ttaagcaata tccctcaaat gagtttggaa
      901 agtttagtga ttcatcacaa atacttaaat acatgtagtt atatatagat tgaggttctt
      961 gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc atccatcttt ccaaaacaag
     1021 cggctaggac atttttgtct cagccgcttg ttttctagtt tattctttca tcttgtcgga
     1081 ccttttttct tgggtataga cttttctcat attctaccac aattttgggt ttccctaaca
     1141 catgatagga tctcacaaca aattgctttc tattattata ataacctgta acgactaact
     1201 tcatcccttc gtctacttca gctaggaagt tcaaactatg ggaagcaatc aaacaattga
     1261 ccccatttaa actgaaacgg atcaacggtc tggcactaac ttgcaaagta cggatcttat
     1321 ctactgttcc atattttttc tccataacct tcacctcaat accattatac gaacatacat
     1381 tccctttgta aagaagaaac tctgttttat ctttttgact ttttgtctat tacctttctt
     1441 aaaatcatat tggcacttcc tgcgaagatg aaggacatgt actaaaaaaa agaggcagca
     1501 gtatagatta ctgttgcttc tttactaatt taggtttact tgttaagaaa gattatttac
     1561 gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt atcttccact tcatcttttg
     1621 ctttttctaa cttttgaata tattgtttca agcttgagtt ttcagcagtt gcttcgtcta
     1681 atttcttttg tgtatctgtt aactgatttc tacatttgtt ttttcttgtg tcagtgttgc
     1741 gatttgttga ttcaaaccat ttacagtatt ttgtaattct gaaagttttg cttgtgcttc
     1801 ttgtagtctt gctgtccaat ctgcattcag atgattgatt tcatcatttt tttggttgat
     1861 ctcatctagt ttgacattga tttcattttg tttgctttgt agttgtgcat ccttgctgac
     1921 taattgactt tctaagtttt gtttttctgc tgccgattga tttttttggt tttctaattc
     1981 atttactttt gtttggtatt cttggacatc tgcctttgaa tcttgcaatg tctgttcttt
     2041 ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct ttatctgtca atgtatgatc
     2101 aagctgtgtc agattctcat tgattgtatc aatatctgtc tctccacccc acaaaataat
     2161 ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat agaaatgcaa cgacaatccc
     2221 accagtaata aatttctttt tcatttgcat agctccttaa tccaatactt ttacatgcta
     2281 aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa ttacatatgt aattttaata
     2341 taaatactat caaatactca tttaatcctc cttttttatc tatttaaaaa atctttttta
     2401 tagagaaaaa tgcaggttaa tactttctta aataaatatt tatggtgaac aaaaacaaaa
     2461 aagcaagttt tattaaacgt aacccttttc atttcataga ttactgtatt tattacaaaa
     2521 aacgcggatt tgtcataaat tgtcatgctt cttttaccta tgaaa
//
LOCUS       DAPBBV010000160         2239 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.116, whole genome shotgun sequence.
ACCESSION   DAPBBV010000160 DAPBBV010000000
VERSION     DAPBBV010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.116"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            216..1127
                     /locus_tag="RD486_002959"
     CDS             216..1127
                     /locus_tag="RD486_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HDT7664591.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1280..1765
                     /gene="vanZ"
                     /locus_tag="RD486_002960"
     CDS             1280..1765
                     /gene="vanZ"
                     /locus_tag="RD486_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HDT7664592.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(2020..2239)
                     /locus_tag="RD486_002961"
                     /pseudo
     CDS             complement(2020..2239)
                     /locus_tag="RD486_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT          786 a          318 c          424 g          711 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccgt atcacttatg aaaattcatc
       61 tacattggtg ataatagtaa atccagtagg gcgaaataat tgactgtaat ttacggggca
      121 aaacggcaca atctcaaacg agattgtgcc gtttaagggg aagattctag aaatatttca
      181 tacttccaac tatatagtta aggaggagac tgaaaatgaa gaagttgttt tttttattgt
      241 tattgttatt cttaatatac ttaggttatg actacgttaa tgaagcactg ttttctcagg
      301 aaaaagtcga atttcaaaat tatgatcaaa atcccaaaga acatttagaa aatagtggga
      361 cttctgaaaa tacccaagag aaaacaatta cagaagaaca ggtttatcaa ggaaatctgc
      421 tattaatcaa tagtaaatat cctgttcgcc aagaaagtgt gaagtcagat atcgtgaatt
      481 tatctaaaca tgacgaatta ataaatggat acgggttgct tgatagtaat atttatatgt
      541 caaaagaaat agcacaaaaa ttttcagaga tggtcaatga tgctgtaaag ggtggcgtta
      601 gtcattttat tattaatagt ggctatcgag actttgatga gcaaagtgtg ctttaccaag
      661 aaatgggggc tgagtatgcc ttaccagcag gttatagtga gcataattca ggtttatcac
      721 tagatgtagg atcaagcttg acgaaaatgg aacgagcccc tgaaggaaag tggatagaag
      781 aaaatgcttg gaaatacggg ttcattttac gttatccaga ggacaaaaca gagttaacag
      841 gaattcaata tgaaccatgg catattcgct atgttggttt accacatagt gcgattatga
      901 aagaaaagaa tttcgttctc gaggaatata tggattacct aaaagaagaa aaaaccattt
      961 ctgttagtgt aaatggggaa aaatatgaga tcttttatta tcctgttact aaaaatacca
     1021 ccattcatgt gccgactaat cttcgttatg agatatcagg aaacaatata gacggtgtaa
     1081 ttgtgacagt gtttcccgga tcaacacata ctaattcaag gaggtaagga tggcggaatg
     1141 aaaccaacga aattaatgaa cagcattatt gtactagcac ttttggggta acgttagctt
     1201 tttaatttaa aacccacgtt aactaggaca ttgctatact aatgatacaa cttaaacaaa
     1261 agaattagag gaaattatat tgggaaaaat attatctaga ggattgctag ctttatattt
     1321 agtgacacta atctggttag tgttattcaa attacaatac aatattttat cagtatttaa
     1381 ttatcatcaa agaagtctta acttgactcc atttactgct actgggaatt tcagagagat
     1441 gatagataat gttataatct ttattccatt tggcttgctt ttgaatgtca attttaaaga
     1501 aatcggattt ttacctaagt ttgcttttgt actggtttta agtcttactt ttgaaataat
     1561 tcaatttatc ttcgctattg gagcgacaga cataacagat gtaattacaa atactgttgg
     1621 aggctttctt ggactgaaat tatatggttt aagcaataag catatgaatc aaaaaaaatt
     1681 agacagagtt attatttttg taggtatact tttgctcgta ttattgctcg tttaccgtac
     1741 ccatttaaga ataaattacg tgtaagatgt ctaaatcaag caatctgatc tttcatacac
     1801 ataaagatat tgaatgaatt ggattagatg gaaaacggga tgtggggaaa ctcgcccgta
     1861 ggtgtgaagt gaggggaaaa ccggtgataa agtaaaaagc ttacctaaca ctatagtaac
     1921 aaagaaagcc caattatcaa ttttagtgct gaggaattgg tctctttaat aaatttcctt
     1981 aacgttgtaa atccgcattt tcctgacggt acccccaaac taagatttca tagatagatt
     2041 ttctgataac tttaaaaaac acgaatagcg gaaaggatgt cttcattcgc taaagagtaa
     2101 taaactactt ttccatcttg acgtgatttt gccattccat gtttttttaa aaaacgtaaa
     2161 tggtgtgacg ttgtagcgac actagcagta agtatttctg cggttctgtt gcaaagtttt
     2221 aaatctacta tcaaataag
//
LOCUS       DAPBBV010000161         1664 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.124, whole genome shotgun sequence.
ACCESSION   DAPBBV010000161 DAPBBV010000000
VERSION     DAPBBV010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.124"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..977
                     /gene="vanA"
                     /locus_tag="RD486_002962"
     CDS             <1..977
                     /gene="vanA"
                     /locus_tag="RD486_002962"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase"
                     /protein_id="HDT7664593.1"
                     /translation="SVKSAIEIAANIKKKKYEPLYIGITKSGVWKMCEKPCAEWENDN
                     CYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKSGEDGSIQGLFELSGIPFVG
                     CDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPVAATFTYPVFVKPARSGSSF
                     GVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCAVLGNSAALVVGEVDQIRLQ
                     YGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETAKKIYKALGCRGLARVDMFL
                     QDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELIDRLIVLALKG"
     gene            983..1591
                     /locus_tag="RD486_002963"
     CDS             983..1591
                     /locus_tag="RD486_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7664594.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          498 a          322 c          406 g          438 t
ORIGIN      
        1 tatcggtaaa atctgcaata gagatagccg ctaacattaa aaaaaaaaaa tacgagccgt
       61 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
      121 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
      181 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
      241 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
      301 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
      361 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
      421 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
      481 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
      541 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
      601 tattgggaaa cagtgccgcg ttagttgttg gcgaggtgga ccaaatcagg ctgcagtacg
      661 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcagttataa
      721 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
      781 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
      841 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
      901 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
      961 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
     1021 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
     1081 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
     1141 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
     1201 gcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
     1261 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
     1321 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
     1381 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
     1441 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
     1501 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
     1561 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
     1621 taagcggttc tgttgcaaag ttttaaataa agaataaaat ccct
//
LOCUS       DAPBBV010000162         1660 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VREC-023
            SAMN36683413-rid18909703.guided.125, whole genome shotgun sequence.
ACCESSION   DAPBBV010000162 DAPBBV010000000
VERSION     DAPBBV010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683413
            Sequence Read Archive: SRR25390896
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831665.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831665.1
            Genome Coverage       :: 302x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 21:08:44
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,965
            CDSs (total)                      :: 2,898
            Genes (coding)                    :: 2,823
            CDSs (with protein)               :: 2,823
            Genes (RNA)                       :: 67
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 36 of 75
            Pseudo Genes (incomplete)         :: 36 of 75
            Pseudo Genes (internal stop)      :: 18 of 75
            Pseudo Genes (multiple problems)  :: 11 of 75
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1660
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683413-rid18909703.guided.125"
                     /isolate="VREC-023"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Edinburgh"
                     /lat_lon="55.96 N 3.19 W"
                     /collection_date="2016"
                     /collected_by="NHS Lothian"
                     /note="genotype: vanA"
     gene            <1..973
                     /gene="vanA"
                     /locus_tag="RD486_002964"
     CDS             <1..973
                     /gene="vanA"
                     /locus_tag="RD486_002964"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase"
                     /protein_id="HDT7664595.1"
                     /translation="VKSAIEIAANINKKKYEPLYIGITKSGVWKMCEKPCAEWENDNC
                     YSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKSGEDGSIQGLFELSGIPFVGC
                     DIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPVAATFTYPVFVKPARSGSSFG
                     VKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCAVLGNSAALVVGEVDQIRLQY
                     GIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETAKKIYKALGCRGLARVDMFLQ
                     DNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELIDRLIVLALKG"
     gene            979..1587
                     /locus_tag="RD486_002965"
     CDS             979..1587
                     /locus_tag="RD486_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7664596.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          496 a          321 c          406 g          437 t
ORIGIN      
        1 ggtaaaatct gcaatagaga tagccgctaa cattaataaa aaaaaatacg agccgttata
       61 cattggaatt acgaaatctg gtgtatggaa aatgtgcgaa aaaccttgcg cggaatggga
      121 aaacgacaat tgctattcag ctgtactctc gccggataaa aaaatgcacg gattacttgt
      181 taaaaagaac catgaatatg aaatcaacca tgttgatgta gcattttcag ctttgcatgg
      241 caagtcaggt gaagatggat ccatacaagg tctgtttgaa ttgtccggta tcccttttgt
      301 aggctgcgat attcaaagct cagcaatttg tatggacaaa tcgttgacat acatcgttgc
      361 gaaaaatgct gggatagcta ctcccgcctt ttgggttatt aataaagatg ataggccggt
      421 ggcagctacg tttacctatc ctgtttttgt taagccggcg cgttcaggct catccttcgg
      481 tgtgaaaaaa gtcaatagcg cggacgaatt ggactacgca attgaatcgg caagacaata
      541 tgacagcaaa atcttaattg agcaggctgt ttcgggctgt gaggtcggtt gtgcggtatt
      601 gggaaacagt gccgcgttag ttgttggcga ggtggaccaa atcaggctgc agtacggaat
      661 ctttcgtatt catcaggaag tcgagccgga aaaaggctct gaaaacgcag ttataaccgt
      721 tcccgcagac ctttcagcag aggagcgagg acggatacag gaaacggcaa aaaaaatata
      781 taaagcgctc ggctgtagag gtctagcccg tgtggatatg tttttacaag ataacggccg
      841 cattgtactg aacgaagtca atactctgcc cggtttcacg tcatacagtc gttatccccg
      901 tatgatggcc gctgcaggta ttgcacttcc cgaactgatt gaccgcttga tcgtattagc
      961 gttaaagggg tgataagcat ggaaatagga tttacttttt tagatgaaat agtacacggt
     1021 gttcgttggg acgctaaata tgccacttgg gataatttca ccggaaaacc ggttgacggt
     1081 tatgaagtaa atcgcattgt agggacatac gagttggctg aatcgctttt gaaggcaaaa
     1141 gaactggctg ctacccaagg gtacggattg cttctatggg acggttaccg tcctaagcgt
     1201 gctgtaaact gttttatgca atgggctgca cagccggaaa ataacctgac aaaggaaagt
     1261 tattatccca atattgaccg aactgagatg atttcaaaag gatacgtggc ttcaaaatca
     1321 agccatagcc gcggcagtgc cattgatctt acgctttatc gattagacac gggtgagctt
     1381 gtaccaatgg ggagccgatt tgattttatg gatgaacgct ctcatcatgc ggcaaatgga
     1441 atatcatgca atgaagcgca aaatcgcaga cgtttgcgct ccatcatgga aaacagtggg
     1501 tttgaagcat atagcctcga atggtggcac tatgtattaa gagacgaacc ataccccaat
     1561 agctattttg atttccccgt taaataaact tttaaccgtt gcacggacaa actatataag
     1621 cggttctgtt gcaaagtttt aaataaagaa taaaatccct
//
